LOCUS       DAFKHN010000001        94653 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFKHN010000001 DAFKHN010000000
VERSION     DAFKHN010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 94653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.001"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="LY912_000001"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="LY912_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBM6953728.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="LY912_000002"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="LY912_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBM6953729.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="LY912_000003"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="LY912_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBM6953730.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="LY912_000004"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="LY912_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBM6953731.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="LY912_000005"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="LY912_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBM6953732.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="LY912_000006"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="LY912_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBM6953733.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="LY912_000007"
     CDS             complement(8557..9027)
                     /locus_tag="LY912_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBM6953734.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="LY912_000008"
     CDS             complement(9073..9498)
                     /locus_tag="LY912_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBM6953735.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="LY912_000009"
     CDS             complement(9565..9834)
                     /locus_tag="LY912_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBM6953736.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="LY912_000010"
     CDS             complement(9845..11440)
                     /locus_tag="LY912_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBM6953737.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="LY912_000011"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="LY912_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBM6953738.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /locus_tag="LY912_000012"
     CDS             complement(14993..15553)
                     /locus_tag="LY912_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBM6953739.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="LY912_000013"
     CDS             15906..16880
                     /locus_tag="LY912_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBM6953740.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="LY912_000014"
     CDS             17050..18450
                     /locus_tag="LY912_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBM6953741.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="LY912_000015"
     CDS             complement(18528..19250)
                     /locus_tag="LY912_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6953742.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="LY912_000016"
     CDS             complement(19329..19835)
                     /locus_tag="LY912_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBM6953743.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="LY912_000017"
     CDS             19958..21757
                     /locus_tag="LY912_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBM6953744.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21825..23399)
                     /locus_tag="LY912_000018"
     CDS             complement(21825..23399)
                     /locus_tag="LY912_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBM6953745.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="LY912_000019"
     CDS             complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="LY912_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBM6953746.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="LY912_000020"
     CDS             complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="LY912_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBM6953747.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25176..25814)
                     /locus_tag="LY912_000021"
     CDS             complement(25176..25814)
                     /locus_tag="LY912_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBM6953748.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25815..26465)
                     /locus_tag="LY912_000022"
     CDS             complement(25815..26465)
                     /locus_tag="LY912_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBM6953749.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="LY912_000023"
     CDS             complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="LY912_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBM6953750.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="LY912_000024"
     CDS             complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="LY912_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBM6953751.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29608..30348)
                     /locus_tag="LY912_000025"
     CDS             complement(29608..30348)
                     /locus_tag="LY912_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBM6953752.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="LY912_000026"
     CDS             complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="LY912_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBM6953753.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31719..32657)
                     /locus_tag="LY912_000027"
     CDS             complement(31719..32657)
                     /locus_tag="LY912_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBM6953754.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32650..33141)
                     /gene="def"
                     /locus_tag="LY912_000028"
     CDS             complement(32650..33141)
                     /gene="def"
                     /locus_tag="LY912_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBM6953755.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33156..35564)
                     /gene="priA"
                     /locus_tag="LY912_000029"
     CDS             complement(33156..35564)
                     /gene="priA"
                     /locus_tag="LY912_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBM6953756.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35817..36122)
                     /locus_tag="LY912_000030"
     CDS             complement(35817..36122)
                     /locus_tag="LY912_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBM6953757.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="LY912_000031"
     CDS             complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="LY912_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBM6953758.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37228..37512)
                     /locus_tag="LY912_000032"
     CDS             complement(37228..37512)
                     /locus_tag="LY912_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953759.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37530..38420)
                     /locus_tag="LY912_000033"
     CDS             complement(37530..38420)
                     /locus_tag="LY912_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBM6953760.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38440..38658)
                     /locus_tag="LY912_000034"
     CDS             complement(38440..38658)
                     /locus_tag="LY912_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBM6953761.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38628..40328)
                     /locus_tag="LY912_000035"
     CDS             complement(38628..40328)
                     /locus_tag="LY912_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBM6953762.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40595..41368
                     /locus_tag="LY912_000036"
     CDS             40595..41368
                     /locus_tag="LY912_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953763.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFLKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="LY912_000037"
     CDS             complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="LY912_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBM6953764.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42084..42186)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42192..43163)
                     /locus_tag="LY912_000038"
     CDS             complement(42192..43163)
                     /locus_tag="LY912_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBM6953765.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="LY912_000039"
     CDS             complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="LY912_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBM6953766.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45133..45951)
                     /gene="purR"
                     /locus_tag="LY912_000040"
     CDS             complement(45133..45951)
                     /gene="purR"
                     /locus_tag="LY912_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBM6953767.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46118..46942)
                     /locus_tag="LY912_000041"
     CDS             complement(46118..46942)
                     /locus_tag="LY912_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBM6953768.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46915..47595)
                     /locus_tag="LY912_000042"
     CDS             complement(46915..47595)
                     /locus_tag="LY912_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBM6953769.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47618..48556)
                     /locus_tag="LY912_000043"
     CDS             complement(47618..48556)
                     /locus_tag="LY912_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBM6953770.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48801..49664)
                     /locus_tag="LY912_000044"
     CDS             complement(48801..49664)
                     /locus_tag="LY912_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBM6953771.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="LY912_000045"
     CDS             complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="LY912_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBM6953772.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52520..53326
                     /gene="proC"
                     /locus_tag="LY912_000046"
     CDS             52520..53326
                     /gene="proC"
                     /locus_tag="LY912_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBM6953773.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53405..54961)
                     /gene="rny"
                     /locus_tag="LY912_000047"
     CDS             complement(53405..54961)
                     /gene="rny"
                     /locus_tag="LY912_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBM6953774.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55372..56421)
                     /gene="recA"
                     /locus_tag="LY912_000048"
     CDS             complement(55372..56421)
                     /gene="recA"
                     /locus_tag="LY912_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBM6953775.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56530..57771)
                     /locus_tag="LY912_000049"
     CDS             complement(56530..57771)
                     /locus_tag="LY912_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBM6953776.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58011..58589)
                     /gene="pgsA"
                     /locus_tag="LY912_000050"
     CDS             complement(58011..58589)
                     /gene="pgsA"
                     /locus_tag="LY912_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBM6953777.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58798..59721)
                     /locus_tag="LY912_000051"
     CDS             complement(58798..59721)
                     /locus_tag="LY912_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6953778.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60460..61746)
                     /locus_tag="LY912_000052"
     CDS             complement(60460..61746)
                     /locus_tag="LY912_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBM6953779.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61739..63007)
                     /locus_tag="LY912_000053"
     CDS             complement(61739..63007)
                     /locus_tag="LY912_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBM6953780.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63259..63720
                     /gene="mscL"
                     /locus_tag="LY912_000054"
     CDS             63259..63720
                     /gene="mscL"
                     /locus_tag="LY912_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBM6953781.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63779..64225)
                     /locus_tag="LY912_000055"
     CDS             complement(63779..64225)
                     /locus_tag="LY912_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6953782.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64318..64563)
                     /locus_tag="LY912_000056"
     CDS             complement(64318..64563)
                     /locus_tag="LY912_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBM6953783.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64677..65255)
                     /locus_tag="LY912_000057"
     CDS             complement(64677..65255)
                     /locus_tag="LY912_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBM6953784.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65332..65862)
                     /locus_tag="LY912_000058"
     CDS             complement(65332..65862)
                     /locus_tag="LY912_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBM6953785.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65866..66726)
                     /gene="rlmB"
                     /locus_tag="LY912_000059"
     CDS             complement(65866..66726)
                     /gene="rlmB"
                     /locus_tag="LY912_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBM6953786.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66719..67114)
                     /locus_tag="LY912_000060"
     CDS             complement(66719..67114)
                     /locus_tag="LY912_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBM6953787.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67111..68523)
                     /locus_tag="LY912_000061"
     CDS             complement(67111..68523)
                     /locus_tag="LY912_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBM6953788.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68520..69056)
                     /gene="cysE"
                     /locus_tag="LY912_000062"
     CDS             complement(68520..69056)
                     /gene="cysE"
                     /locus_tag="LY912_000062"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBM6953789.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69142..69381)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69378..70838)
                     /locus_tag="LY912_000063"
     CDS             complement(69378..70838)
                     /locus_tag="LY912_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBM6953790.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71008..72165)
                     /locus_tag="LY912_000064"
     CDS             complement(71008..72165)
                     /locus_tag="LY912_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBM6953791.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72199..73569)
                     /gene="radA"
                     /locus_tag="LY912_000065"
     CDS             complement(72199..73569)
                     /gene="radA"
                     /locus_tag="LY912_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBM6953792.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73632..74159)
                     /locus_tag="LY912_000066"
     CDS             complement(73632..74159)
                     /locus_tag="LY912_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBM6953793.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74389..75195
                     /gene="proB"
                     /locus_tag="LY912_000067"
     CDS             74389..75195
                     /gene="proB"
                     /locus_tag="LY912_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBM6953794.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75192..76439
                     /locus_tag="LY912_000068"
     CDS             75192..76439
                     /locus_tag="LY912_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBM6953795.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76515..76859
                     /locus_tag="LY912_000069"
     CDS             76515..76859
                     /locus_tag="LY912_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953796.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76976..77302)
                     /locus_tag="LY912_000070"
     CDS             complement(76976..77302)
                     /locus_tag="LY912_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953797.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77917..79119)
                     /locus_tag="LY912_000071"
     CDS             complement(77917..79119)
                     /locus_tag="LY912_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6953798.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79236..79751
                     /locus_tag="LY912_000072"
     CDS             79236..79751
                     /locus_tag="LY912_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBM6953799.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79950..80396)
                     /locus_tag="LY912_000073"
     CDS             complement(79950..80396)
                     /locus_tag="LY912_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBM6953800.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80443..81921)
                     /gene="msr(C)"
                     /locus_tag="LY912_000074"
     CDS             complement(80443..81921)
                     /gene="msr(C)"
                     /locus_tag="LY912_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBM6953801.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82275..82904)
                     /locus_tag="LY912_000075"
     CDS             complement(82275..82904)
                     /locus_tag="LY912_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBM6953802.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82888..83352)
                     /locus_tag="LY912_000076"
     CDS             complement(82888..83352)
                     /locus_tag="LY912_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBM6953803.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83839..85107)
                     /locus_tag="LY912_000077"
     CDS             complement(83839..85107)
                     /locus_tag="LY912_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBM6953804.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85338..86075)
                     /locus_tag="LY912_000078"
     CDS             complement(85338..86075)
                     /locus_tag="LY912_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBM6953805.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86142..86711)
                     /locus_tag="LY912_000079"
     CDS             complement(86142..86711)
                     /locus_tag="LY912_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBM6953806.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86839..87711
                     /locus_tag="LY912_000080"
     CDS             86839..87711
                     /locus_tag="LY912_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBM6953807.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88053..88925
                     /locus_tag="LY912_000081"
     CDS             88053..88925
                     /locus_tag="LY912_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBM6953808.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88922..90880
                     /locus_tag="LY912_000082"
     CDS             88922..90880
                     /locus_tag="LY912_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBM6953809.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91212..92063)
                     /locus_tag="LY912_000083"
     CDS             complement(91212..92063)
                     /locus_tag="LY912_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBM6953810.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92186..92653
                     /locus_tag="LY912_000084"
     CDS             92186..92653
                     /locus_tag="LY912_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBM6953811.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92916..93398)
                     /locus_tag="LY912_000085"
     CDS             complement(92916..93398)
                     /locus_tag="LY912_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBM6953812.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93498..94361)
                     /locus_tag="LY912_000086"
     CDS             complement(93498..94361)
                     /locus_tag="LY912_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBM6953813.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT        26428 a        20365 c        16991 g        30869 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgccacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ctgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttgattaatc attcttacat gctgacagca
    21841 aagtcagggg caaaccattg aactgaacca acttttacgc tttcgcctgg ttgaggagca
    21901 tggatatatt gtcctccgcc taaagcaatc gctacgtggt aagttccgcc ttgtgacccc
    21961 cagaataaca agtctccagc ttttgcttga gaaactgaaa tttttgttcc agctgattct
    22021 tgaggaactg tccaaccacc gatgtcacga ccagttactt gcatgtaaac atagcgtgtg
    22081 aaccctgagc agtcaaagcc acttggatct ttaccgcccc aaacatatgg agtaccaata
    22141 tatttgtaag cttctgctac gattgctgca ccattcacac ttccagaagg agctggagca
    22201 ggtgttacag gttttggttg ttcaggtgtt ggtgttggcg ttggagccgg agtactactt
    22261 cctgtgccgt ttcctgtatc aacactttga tctgttgatg gtgttgtagg cgcaggtgtt
    22321 gttgattctt ctgttgttga agattcaggc actgttgttg attcttctgt tgctgaagat
    22381 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcgctgttgt tgattcttct
    22441 gttgctgaag attcaggcgc tgttgattct tctgttgaag attcaggtgt tgttgattct
    22501 tctgttgctg aagattgtgt agctgatgat gattcttcag tcattgaaga ttgtgtagct
    22561 gatgattctt ctgttgctga gctttgtgca gtagatgaag cttgagtagc ttgtgcttca
    22621 gcctctgctt gttcgcgtgc ttctttttca gctttttctt gtgcagcttg ttgacgagct
    22681 tgttctgcta gacgttgttg ttcacgaata cgagcttgct ctgcttcagc ttctgctttt
    22741 tgacggttca agtcagcttt cttgtcttca gcagttgctt gttcagcagc taatgaagtt
    22801 ttcagtacgt tcaaatcagc ttgtttagat aaaagatcgc ctttttgaga ttccaaagca
    22861 gcttggtttt cagctaattc ttttagttta gcatcgtttt cagctttttt gtcttctaca
    22921 gcttttttat cttgtttttg ttgttccatc aagtcgttgt ttgcttttac catcgttgtc
    22981 attgcttgaa cgcgtccaat agcatctgct aatgaatcag cattcaatac agcatcgatg
    23041 tagtttgagc ttgtgttgct tacttgtgct tcgcgtgctt gtttttggat tgtatcttca
    23101 cgtttttcaa tacgttcttg taaatctgca atgtctttta ctaattgtgc agattcttga
    23161 cgcaatgtat cttgttttgc taataggtct tgtgcttgtg tgttgatttc agaaacttgg
    23221 ctttctaagg catcgatttg tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc
    23281 ttttgatctt gctgttgtat ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat
    23341 gctacggcag tcaaggtcat tgaacatacc attactgctg atattaaact ctttttcact
    23401 cttcattcct ccgactggct taatttaata aatatctaaa tatatttaag tctttcttaa
    23461 cgatataaaa attgtaccat agcagtgtgt caacgatata atagttatgt tacaaaaatg
    23521 tttcaaaaca acttttaaaa atgacaaaac tgttcgtttc agaaaatgat catgaaaaag
    23581 ccgcgttaag tctagcattt cttaagataa caacgattct ttttcgcttt cgacctaaaa
    23641 ataaaaaaag aaattattca tcactgaata atttcttaaa gggaaaaatg aataatacaa
    23701 atataatcat gttcaacagc agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat
    23761 ttactactgc taatttaaaa atcaactgga ccaccatcgt aaacaattca taacccgtga
    23821 caaagatgat catactgaaa aattcagtaa agatgttgac atggataacg tctttcatta
    23881 catacatcaa ccatacaatt aaagggagag ctactgcata gataccgata acgccaatat
    23941 agtaagcgtc atagatagcc ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa
    24001 acgccatact gcaacataat aatgccaata tcagaaagtg ggcatttgac atataggtgc
    24061 ctttcgacca ctcccctagc attcttgtta aatgaccatc tatcaacatc aaaaagaaca
    24121 aaacgattgg cagatagtac ttcattgttt ctttcttcaa catggactaa tcctccgcta
    24181 gccgttggac aatcgtcaca actgacacgt catacatttc tgcataaggt ttcacataaa
    24241 cttcccgatc cagcccataa ctatctggtt tcgttttaat aaccgtaccg atcggcaagt
    24301 tagctggaga attccctcca agaccggatg tctggacaac atccccttct ttgatatccg
    24361 tatcaccagt taattgggtc accactaagg catggagctt ttcatcatag tttttaagca
    24421 aaccaaacgc ttcgccatta gccgaagata cccgtactgg aaaatgattg gagctttcat
    24481 tagaggatga cagtaattcg attttagacg aagccgtatt gacctcgatc actcggccaa
    24541 tcaatccttt ttgcgacatg actgccatat ttgcttcgat accgtcttta gaacccttgt
    24601 ctacgatcag catgtcctgc caactgtcag gcgaacgagt aatgacattt gccgttactt
    24661 tttcgtaact agtcagcgtc tgattcaact caagttcttt tttcaacgct tcgatttctc
    24721 tctcgtaatt cttgttttgc tgtgaaacgt catcatagct atcgattttt tcttttagcc
    24781 gctcattttc ggcataagtt gaaaaaagat tatggacaga atctactcca tttcgtaccc
    24841 accgtactgg ggcagagatt gttttatcaa ccattgcaac actgtcatta acgatggatt
    24901 ggaagaaatt gggctttcct tcattcgctc gctgcgcagc ggtcacactt agtatcgtca
    24961 ccacgatgat aacaataacc aaggtaataa taatattttt attaggattg aacttcttca
    25021 caaagacacc tcgaattaat tagactcttg tgttcaattt tatcactaaa tgccgtgaaa
    25081 caaaaggtaa gttgctcctc ttaagctttt ttttagcaaa taatagattc tgtcattttt
    25141 agcctgaaag acaaattttt ttatttgttt atggatcaat ctttgctttg aataactgca
    25201 atcataccat ctgaaaaaga aaattctgcg gtatctgaaa gaaattcgtt acttgcataa
    25261 gatgtcggat attctacttc tttattttcc aatacatact tgctgccttt taatgtaaga
    25321 ttcgagacgg gagtcaagca gcaataagct aaatacttca tatctggtat ctgtcttact
    25381 atatgctctc caggcaaata ataagacaaa taattttgac aatctctgat aataagctga
    25441 tgggcaaagg gtttgaagcg aggttccata cctaaccaga gattggctaa aagatgatcc
    25501 aatcttccgc ccgtagctcc aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt
    25561 tttaagatac ctaactgtgt atctgtatcg tctttttctg caggggaacg ggtatactct
    25621 ttggcttttg caaatacttc cttctgctct tcgttcgaca atgaatcaaa atcacccact
    25681 gccagatcta ctgggtagcc tgcttgaagc aggtacagcg caccacggtc tatcccgaca
    25741 taggcatcgt atttggacag cagagactgc ggccagtttt gcggattacc tccagcagct
    25801 aataaaattt tcatttagtc taatgcctct tttaatcgtt cgatttgtcc gactggattt
    25861 tcggctccat agatatatga tcctgcaacg aagacatccg cccctgcatc tttacagatt
    25921 tttgctgttt ctggaacgat tccgccatct acttcgattg cataagtcca attgttctct
    25981 ctacgtagat cagcgagttc cgtaattttt tctactgttt cttcaataaa gctttgtccg
    26041 ccgaacccag gattgacagt catgactagt acttgatcag ccaaaggcaa aacatgtttg
    26101 atcatggaga ctggtgttcc tggattgata actactccag ctttaactcc taagcttttt
    26161 gtcatttgaa gtgcccgatg aatatgagga gttgcttcga cgtggacagt aatgatatct
    26221 gctccagctt ttgcaaatgc tggaatgtag ttttctggat caacgatcat cagatggacg
    26281 tctaacggta atttagtaac aggacggatt gcctgaacaa tatttggccc taatgtgata
    26341 tttgggacaa atcggccatc cattacatct acgtggatgt aatctgcgcc tcctttttcc
    26401 actaactcaa tgtctctttg taaattggca aaatctgcac tcaaaatgga tggtgctatc
    26461 ttcattcttg tttcctccta ttttcgttta ccttcttttt ttgcatacat tggttttctt
    26521 ttttcgattt cttgtaagaa ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct
    26581 gtttctactc tatgttttac ttcgcagcca ggttctttag catgcatgca ctctctaaat
    26641 ttgcaatgga cagaagcttc tacaaattca ggaaattgtc tcggcagttc tcctgcttca
    26701 attgtcaaaa agtcaatcga gctaaatcct ggtgtatctg ctactaaccc gccatagata
    26761 ggaatcagtt ccacatgacg tgttgtatgc cgtcctcttc caagtgcatc agaaatctct
    26821 cctgttgcta aattcagttc cggtgatatt tgattcagta gcgtcgattt tcctgctcca
    26881 gactgaccca taaagaccga tagccgttct gggaagtaac ggatcagttc tgtcgtatca
    26941 cccgtatgat tgggtacaat caccggatag cctattttag tataggtttg cttgatctct
    27001 tcgatttttt ctgggtcgtc tgacaagtcg gtctttgtca aaaaaataat cggttcgatc
    27061 gactcgtatt ccaaggtaac tagaaagcgg tcaagtagat tataagaaaa tgcaggctct
    27121 acgatacttg tgacaatgat tccaagatca acatttgtga ctggtgggcg aactaattga
    27181 ttttttctcg gcaagatttc cagaagatag ccgtctgttt gattttcact ctcaaagatc
    27241 acctgatctc cgacaagcgg cgtgattttc cgattccgga aatttcctct tcctcttgtt
    27301 tgataggtct ctccgtttgc gtatacatag taaaaaccgc tgattgcttt tctgatttgt
    27361 cctttgataa gtgccacctc cgtttttgtt tattttacca tacgaagagg aaagtaggtg
    27421 ttattccatg caaacttctc aaagtatatg gcttgaaaat tgatcaaaag agatagaaac
    27481 acaaaaaaga gaatgcaaca aatcaatgtc gcattccctt ctgatatatt ttattcagca
    27541 cttattttga actttctgag gtgctagctg atgaacttgt ggagctggaa gattcttctt
    27601 ttgaagagtt gcttgtgcta ctggagctac ttgagctgct agaactgtct gaagagtctt
    27661 tttcagaact agaagacgct ggatctggtc ctttagagta aattacgttc acaaccattc
    27721 ctttggtaat tgtcgttcct gcccctggta ctgtacgaat cactttatct ttatccaccg
    27781 tgtttgaata ttcggaagtc tcatgcccga tatattctgc accgacacta gctaaataac
    27841 tttgtgcttc gctttttgta tagccggaga tatcattcaa tttaggctct gttccttggc
    27901 ttacgacaaa attgatgtaa gtttcttctg ctacaacttc acccgaggct ggatcctgac
    27961 tgatgatcga acctgatggt acagtgtcgc tatagtcata agtagcacta atattattga
    28021 tattgaatcc ttgtgtaaca agccaattac gaacagtttc gtagttttct cctacatgac
    28081 tactcaaagt cactgtttct ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag
    28141 gatcgacttc tgtatcttct gatggagatt gcgaaatgat cattccgctt tctacctctg
    28201 aactgaattc ctcttctttt tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg
    28261 cttcggcatc ttcataactt ttaccactgt aatcatctaa tttgattttt ttcgtgccgc
    28321 tactaatata cagagtgact tcgcgttttt gcttgactgt cgttcccgct gccgggtctg
    28381 tcttcactac attaccttct tcgattttgt catctgcaat ttcttctgtt tttgttgcta
    28441 cttctaattt cgcttttgcg agtgtttctc tagcagaagc ttcagaaaga tcagaaacat
    28501 caggaacaac aacttctcct cgcccgccag aagcaaagaa tacagctgtt ccgattccta
    28561 aaacagcaag aatagctaat aggatcagcc accatttttt ctgtcctttc tttttaggat
    28621 caggcagaac ttcttcctcc tctggtaagg tttcgttttc tggcttgtct tttggcagag
    28681 gcatagattt gaatgaatca ggcattggtg catcttccgt aaggggtgtg ataacttttg
    28741 tttcattatc catcacatga ggctgccatt tttcttcgtt tgcacgagct ggtgataata
    28801 ctgtagaaag atcatcagac atttcctcgg ctgacttata acggtctgca ggttctttag
    28861 ccgttgcccg taaaatcacg ttttccagtg cttgtggcac atttggatca agtgctttta
    28921 tagatggaag atcatcttga aaatgtttta aagcaattgt tacagcagat tcaccatcaa
    28981 acggtacgct acccgtcaac atctcataaa ggatgatccc taaagcataa atatctgact
    29041 gcttcgttgc catacttcct ctggcctgct caggggacag ataatgaaca gatcctagca
    29101 tcgtattcgt ctgcgtgatc gatgtttcag ataaagcgat agcaatcccg aaatccgtga
    29161 tttttacaac accttcatta tcgatcagta cgttttgggg tttcaaatct cggtggatga
    29221 tttgatggtt atgagctaaa gaaatagcag aaaggatctg ctgcataata tttactgctg
    29281 tttcataagg aacaggataa tgtgtttgga tatatcgttt caagtccatt cctttgacgt
    29341 attccatcac cagatactgc atgttgtctt cttcaccaac atcgtaaaca ctaacaatgt
    29401 ttggatgaac gagttctgtt gctgctaaag cttctctctg aaatcgtcga atcgcagtct
    29461 ggtcattttg aaagtcaaat cgtaagactt taactgctac atcacgatcc aagattaaat
    29521 cgtgcgccaa aaatacattt gccataccac cgctaccgat atttccagtg atttgataac
    29581 ggccatttaa ttttttgccc aactcgatca tacactgtcc tccttatatt cgataagaag
    29641 aacggtgata ttatccgctc cgcctgcttc attggcacga tcaatcagct cagttacttt
    29701 atgagacaat gggccttctt gattgatgat cgttcctatt tcttcttcag acagcatgtt
    29761 cgtcaagcca tctgaacata acagcagtcg atcttttagt tgccaaagat gagtagaaac
    29821 atctacttcg actgttccag gcatgccgac agaacgtgtt aaaatatttt tccttggatg
    29881 gttcactgcc atttcttcgc tgatttctcc tgatttgact agttcattga ctaaagaatg
    29941 atcctccgtc aattgcatga ttttatcttc acgaatcaaa taagctctgc tatccccaac
    30001 attggcaatc gtgaaccagt catctgacag agcggccgct acgattgttg ttcccatacc
    30061 gttatattcc ggctgttctt gtccacgctg ataaatcagc atattttctt cttgaatcga
    30121 ttgaatgaac cattgggcga ttttttcatc gtcaacagct tcttgttttt cccaagcttc
    30181 gcctagattc gttaccgcca tctgactggc aatgtctccg gcacgatgac cacccatccc
    30241 gtctgctaat acagcaagct tgagacctga acggctggta aatacactgg catagtcttg
    30301 atttgtgtta cgtcgtcttc ctacatctga ttgatattca atctgcattt tttcacctca
    30361 ttactttttg cgcaaacaac aaatgaaaaa tccatctgtg taaaactgat gcggatacaa
    30421 agtcaacatt ttctcttcga ttgatgattg tagcatagga ttggtcaaaa catcaatcct
    30481 ctcaaaatca gggtgtcttt ccaagaaagc agaaacaacg tcttggtttt cttcttttaa
    30541 gatcgtacaa gtgctataag tcagaatacc ggaagacttt aaagttggtg cgcagctttc
    30601 taaaatttcc aattggattt ttggtaaatt cgctaattca tccggctgtt ttttataacg
    30661 aatatctggt tttcgccgaa gcagcccaag acctgaacaa ggcgcgtcta ctaaaatccg
    30721 atcaaactgc tctgcttcga actgtttact gacttctcta gcatccatct tttgagcgta
    30781 gacagcagaa gagacaccta gacgtgctgc attatcttca atgagtttga ctttgtgttc
    30841 gtgtacatct aaagcgacca cttctccacc gcatgacgga tctaaaaaag aagcaatatg
    30901 cgtcgtctta cctccgggtg ctgcacaggc atctaagaca tgatgttcag gctcgatttg
    30961 catagacggc gctacaagca tcgaactttc atcttggatc gtcatgacgc catcgtggaa
    31021 caatgagcta gaagctaaat gccctttttt cgctactata ccgtatggac tgacttggct
    31081 tttttcagct gtgatctctt cttcttgcaa aacagtgatg gcctgatctc tggaaagtcg
    31141 gcgtgtatct actcgggcac tagcatggct aggctgatat agcgataaac cgagcttttc
    31201 agtttcttcg tatccgattt gatccaccag tcgtttcgtc atccatagag gcaggctgat
    31261 tttgacagaa agtctttcga taggatcagc aatgccttgc agatctggtg ctccttgacg
    31321 ctgataattc ctcaagacac catttacaaa tttccctgtc ccaggatttc cttttacttt
    31381 tgcgatttcg accgcctcgt ttaaaatagc atgtgcaggg actttatcta aaaattctaa
    31441 ttggtataca gaaagataaa gaagcatctt gacccagtca tccacttttt ttgctttagc
    31501 gatcaatggt gcaacgtaaa attccaatag tcgctgatgg ctaatcgtac catagatcaa
    31561 ttctgtaaat aaacccacat ctttttgatt tagctcgctt tgtttgatca tctcattcaa
    31621 caaaagattc gagtaggcgc cacccttgtt cactcgctct aatgtcagta atgccatata
    31681 tcgtactgat tttttcattt ttttagggat ttttttcatt atttcacctg ctgaccaatc
    31741 tgaacttgct gaccgcttcc gttaaggaaa tcatgtacgg cctgttttcc tttaccagct
    31801 ggctgtaatt cattgatggc taagacggtc tgtttaccgc aagcaatcca tagatttttt
    31861 ttgtctttcc ggatgatcgt accaggtgct ttgtctgtag tttctgccaa tacttcaacc
    31921 gataataatt tccagcgtat gccctcatag gtcgtgaatg caattggcca aggacgcatt
    31981 ccgcgtactt ggttgtcaat ttcttctgca gttttatgcc aatcgattgc ttcttgttcc
    32041 cgtgtgatgt ttggcgaaaa agttgcttct gactcgtctt gaggtactgg tttttgtcca
    32101 tccaaaatat tgggcaatgt ttctagcaat agctttcttc ctaaaaggct aagcttttca
    32161 aacatcgtcc ctacatcatc ttgtttagtg attggtatgc tttcttgcgc atagattccg
    32221 cctgcatcca tttttttgat catttccatg atcgttacac cagtttcttt ctccccattc
    32281 atgatggcat aatgaacagg cgcacctccc cgatatttag gaagtaaaga agcatggaca
    32341 ttgattgccc ctaattttgg tacttgcaat aacttttcag gcaagaattg gccaaatgcc
    32401 gcagtgacga tcacatcagg caccaattca atgatttctt ccatttctgg cgaaccggag
    32461 attttctctg gctgcagcac acggataccg tgcttcagag ccgctttttt taccggtgtc
    32521 ggcgtaatta ctcgtttccg cccaactgga cggtcgggct gtgttaccac tgcctggatc
    32581 tcgtaacctg attctatcag cccttcaaga atcggcacag aaaaagcagg tgtgcccata
    32641 aatactagct tagtcatcaa gatgttcctc catatattct tcaagttctt cttccgggat
    32701 ctgctgtatc attttctcaa tgaacaagat accgtctaag tgatcgattt catgctggaa
    32761 ggcacgggct aaatagccaa aagccgtcac ttctatctct tctccgtctc gatcataata
    32821 acgcacggtc acttcatctg ctcgcttgac cgttccatag acatgcggaa tactgagaca
    32881 accttctacg tcaaggcttt caccttttgc ttcgatgatt tctgggttaa tcagttcaaa
    32941 tttctcgcct tcatctactt cgatcacagc aattctcttg ttttgtccta cttgaggagc
    33001 agcgatccct attccgtcat tcgcaatcat tgtctcatat aaattgtcta ataaagcgat
    33061 tgtctcgtcc gtgattacat cgattggctg agcagttctt tttaatttat cattagggtg
    33121 gatcaatata ggatagcgca taatttggcc ctttcttaaa taaagtttaa tggttcgttg
    33181 tcaattgcca caaaaagacc ttgtcgctgt tctttctggc ttccattcaa aatttcatcc
    33241 aaaacatgag gaagattcgg ttcatgttta tatttgatga ttagttgata ataatatcgg
    33301 tttttcactc tcaaaatcat gctgggcgtt ggccctaata gcaagctttg agggcttaac
    33361 acttctttta gctgattggc aatctgaaag attttctttg ccgctacttg ttcttcagga
    33421 tggctggcgg ttattttcac agtaaagtaa taaggaggat agcctccacg atgccgtaca
    33481 tgcatttcct gctgataaaa ctgctcataa ttttgttttt tagccaattc tatggcgtaa
    33541 tgttgaggat tgaatgtttg gatcacgact tcgcctgctt tttccgctcg ccctgctcgt
    33601 cctgaaactt gggtaagcaa ttggaatgta tgctcactag aacgaaaatc cggtaaattc
    33661 agggaggtat cagcattcaa caccccaact aatgtcactt ctggaaagtc caaaccttta
    33721 gcaatcattt gtgtccctaa taatatatct gcttcttttg caccgaattt ttgtaaaatc
    33781 tgttcgtgtg ccccttttct tcgagtggta tctacatcca tacgcaaaat cctagcttgc
    33841 ggataaagtt ctcggagttc ctcttctact ttttgagtac ctgttccata gtagcggatt
    33901 ttattgccgc cacaattagg acagcgattg ggaataggtt cttcatgtcc gcaataatgg
    33961 cagcgcattg aacgtgtatc catatgcagt gtaagagaga tatcgcaatt aggacatgga
    34021 agaacaaatc cacagtccct acacatcaca aaagacgaat atcctcgacg attgagcagt
    34081 aggacagttt gttctttttt gtctaatcga ttttgtattt tttcctgcaa attagcagaa
    34141 aaagtagagg tccgatgatt ctgaaactct tcacgcatat ctacgatctc aatagctgga
    34201 agctgtgcag ctgctttggc tcggtggttt aactgcaata actgataaac gcctttttga
    34261 gctcgtgctc ttgattctaa agagggcgtc gcgcttccta gaactattgg gcaatgatga
    34321 tatttactgc gccaaattgc tagatctctc gcatgataac gcggtgtctc atcttgtttg
    34381 taacttgatt catgttcttc atcgataatg atcagcccga tatttttcag cggggcaaaa
    34441 atagcagatc gtgcgcctac tactacttgc gcttcttccc gctcaatctt gcgccattca
    34501 tcatattttt caccttggga aagtccgcta tgtaagaccg caactgattc tccgaagcgt
    34561 cctttgaatc gctcgaccat ttgcggagtc aatgcgattt caggcactaa cataatagcc
    34621 gttttatttt ctgacaaaac atcagcgatt gcctgaagat atacttctgt tttcccgctg
    34681 ccagtgattc cctccagcaa aaagacctga tctttttgct gctgacctgc tgtgatgatt
    34741 tgttcgacag catttttttg ttctgcattc agttccaatg ccgtcgtttg gtcaaatact
    34801 cggtctttat aagggtcgcg ataacgttct gattctataa actccagcca gcccttttct
    34861 tttccttgat tcaagacagc agtactgatt cctttatttt tgaaataagc aattggttct
    34921 tcttggctca gttcagataa acacaaaaga agttcttttt gtttcttggc attttgccgt
    34981 aattttgccc attcttcttc gatttgcttt tcagttaaca aagaacggac caaacgaatc
    35041 gtttttactt tatttcgtgt atggacttca tatttgatat ctactaattg ctcttggcgc
    35101 cagcgaatca attgagaaag gctgccttct tcttctgctt ccttccagga aatcacttct
    35161 cgctgatcaa acaatacctg aacttctggt gtgtctgcca aaggatagat caatttatca
    35221 tattctgctt tcatcacact cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa
    35281 gtaatttttt tcatataatc agctaatgaa agtaattctt cattgaccac cggagcaagg
    35341 tctagcaaac gaataactgc cttcaaagat ggattagctg attcttctga tttttggata
    35401 gccataacaa atccttggac atgacgattg ccattaccaa aagggacttc tactcgcatc
    35461 ccgacttgca aagctgtttc catttcagag ggaaccaaat aagtgaatgg ctgatcggtc
    35521 tgcatagtag gtacgtccac aatgacttca gctgttaatg tcatggttcg tttcctcctt
    35581 tttttgtctt ttcttatcaa gcgacaaaaa gttccttgcc tattttacta gagatcgatg
    35641 gatttgtctt atcttctgcc aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag
    35701 aactgtgtca aaaagttcag acacagcctt ttctaccaga caataagtgg cgaatgtttg
    35761 aaaaggaaac agctgggttt gcttttcttt ttagatgttc gctctatttt tctttattac
    35821 attttttgct cttcacggat acgtgattcc aattcgtgtt gttcacgctc tttttgtgct
    35881 tgacgttcct cttcttccat cttcaaacgt tcacgtttta attcaggatg tggatcattg
    35941 actacatttc ctgcatcgat ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa
    36001 gaatctagag taggctgtgc acttgcatcc aattcatgcg cgcgtttact tgctaaaatc
    36061 actagagaat attttgaatt tacacgatct aatagtgagt caattgaagg ttttaacatc
    36121 ataagactac atctccttta acattttaat atatttaccg attacgcgat ctactcgaaa
    36181 atgttcactg gcaataatgt ttttgattcg ttcaactgct agcggcactt catcatttac
    36241 aacagcatag tcgtaaagag ccatcatttc gatttcttct tttgcaactt tcattcgttt
    36301 ttcgattact tcatctgcat ctgttcctcg gcctacgatc cgtgatttta attccgctaa
    36361 atctggcgga gtcaaaaaga tgaatacacc atcgggcact ttttctttga cttgttttgc
    36421 tccttggact tcaatctcca agaaaacatc ttttccttca tccaatgtct tgttgacata
    36481 tgacaaagga gttccataat aattcccgac atattctgcg tattccagca tctctccagc
    36541 ttcgatcatt gattcaaact cttctttgct tcggaagaaa taatcaacgc cttcgacctc
    36601 cccttcacgc attttacggg tagtcattga gatcgaatac tgaaaatcat tatcctcact
    36661 ctcaaaaatt gcttttcgta ctgtgccttt tcctacaccg gatggaccag acaacacgat
    36721 taataatcca cgctctgaca tgacgacgtc ctttcaacta gtctttttgt acttatcgtt
    36781 tattttgcac tttttttctg caactttcaa ggttatcttt aattatagct agaaattggt
    36841 aaaaaagcta ccctgtacca agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa
    36901 cagccaaaca taaacagctt ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc
    36961 aagcttttga acgccgtgta taagaggtcg tgaagaagcc gattagtttc gagtatgaag
    37021 aaaaattttg tgaaaatagt ttctcacatt tttgcataaa tttggcttaa taccgagaaa
    37081 atggtttttg aacatcactt attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca
    37141 acctttaaat gtattcctag agcaaagaag ctaagcgaag aaatccaatt ctgtttattt
    37201 attgtatttc tttgttcagc atccttgcta aaagcccata ttggacaaag tattcactac
    37261 acccatgatc tcatcttttc gagaacgtgc tttttctgtc ggatcttcta cctcttctgt
    37321 gtcaattcga acaataaatt tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat
    37381 aaacagttcg ttctcattat agtctgcaca ggcatctttc catacgtcaa agccgttttt
    37441 ttcagaaggg atatcccgtt taaccacagt ttttccactt aattcgtgga acgttacgtc
    37501 ataatatttc attatctcta cctctttcgt cattcaatat tttgtacttg ttctctgatt
    37561 ttttctaaga tcgtcttaga ctggacgact tgatttttaa tttcgattgc atttgatttg
    37621 gaaccgatcg tgttgatttc ccgattcatt tcttggatca ggaaatctaa ttcccgacct
    37681 acaggacatt gtgcttcgat aagttcatct agtttttgta catggatcgc cagacgatcc
    37741 agttcctcgt gaatatctcc gcgttccaac aagatggcta gctccgtcaa caaccgttgc
    37801 tcatcgactt tcgctccaag aaattcctcc agcttttttt gataccttat ttgaaattcc
    37861 ttttcataga tttctacaaa actatcgagt ttttttagta cttctttgaa ttcttcagta
    37921 ttctttttca acactaaagc taaagcttga ccttcttttt ctcgactcgc ctcaatagaa
    37981 tcaagtgcgc ttttcaatgt atctagagct aactgtgcca attcttccat gctctcttcc
    38041 ggtttttctt ctaccgttac gaagttttcg tccagcacga agcgttccgc catccgacta
    38101 attgacactt gattttgact accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata
    38161 agtgaatcaa tcaattccca gttgatgacg atctgttttt cgtttttgcc aatataagct
    38221 agattcacaa atacttcgat tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa
    38281 tcgttttcaa caaagttcag gattttagga cttcgtattt gaacatctag aaaacgctgg
    38341 ttgacacttt ttatttcaat atctaactga tacgcttttg tttcgcggat ggctttgcca
    38401 aaaccagtca tacttttcat tcgacagggt ccttcctcat tacatatttt ctattgcttt
    38461 ttgcagttgt tcaaactctt cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc
    38521 tggcgcccaa tctcgaagat cgaattttgg cgggcgacca ttccagctga ctaggttcag
    38581 ttctttacgc caccccttgt tgttttctga caatatagcg atttcttcta cgatttcata
    38641 tgaaaattct tgtgccatgg ttgttcctcc ttgagataat ataaatatag gatcagtaat
    38701 gtgtcaactg gttgcttaag caattcatgc tgcaaacgat ccttgcgttt tccttgtagc
    38761 agataatcaa aataaacagt tttcgtgcgc tcattttgta ttttttgctg gtattttcga
    38821 taccttcgcc attcttcagt acttaattga ccaatttgtg ccaataaatc atccggcata
    38881 ctttttatat cttgttggca gatcatttga atcatcatgt ctacttgata gatttcattg
    38941 ggcagtaaaa aatgtttttt tgctaaaagt tctagcatcg ccaatccgca tgtctctggt
    39001 acgaccctgt tcttatataa attacgcagt ttttgccaaa attttatgct tttgaaaaaa
    39061 gataattcta actgaatttc ttttgttaag taagacaaaa atcctcgcca gtatgttctt
    39121 gcaggtttaa cagaatgaaa tgtataccag ttcccatagt aatagcctaa tcgttttttc
    39181 atttccagat agcctaattg taaatttaat tggttccttt ggctatcaaa aagcagaaag
    39241 ctgcctagtg tccacaatgt ttgacatttc caatggataa aaatgtctgg catacgaatt
    39301 tttttcgctg ggcctggccc ttgcacatct acgacaaatg cctctgttgc tcctttgtta
    39361 atcgcaatat caataggtat tttgttgcga tacccaccgt ctgcatattt attttttccg
    39421 atctttcgat aagccatagc gggataaaat gaagcagagg cgagtatcca atctggtatt
    39481 tcttctgttt ttgtctgttg gatatcagtc actacttccg ctagttctgg cagtttagta
    39541 gacaccgtat ataaacgtat tttgggatta tgtttgagta aggacaaatc caaattgtct
    39601 ttgaccatct tttccaatgg agcagaagaa accccgcctt caattagtgc tgttttcgtc
    39661 atttggcgtc tttctcgata gaagcgttca cgaaggtctt caactgcagc catttctggt
    39721 aacgcaagca cttgtcttgt cgacagcttt ttccataaat tcacagcttt tttcatatct
    39781 ccttgtaaaa tcaatgcgcc gttcaacgca cctaccgagg tacctgtgat aatctcaaag
    39841 ttgatatcat gttccttcag cgcctgccac acaccaatct gataagcacc gtgcgctcct
    39901 cctccaccta aaacaagtgc tgtatgatag accagctttt tatttaattg tgtggttcct
    39961 tgatagccgt ttttatgaaa aatacgcaac cattcttctg atagaggaga ttgaaataaa
    40021 aaacaacagt tttctttaat aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt
    40081 ttccattcaa aagtttcacc ttcaatcaac agattattaa aaataacatc tcctctactt
    40141 ttagcaatag taaaatagac ggtatatttt ttcgatactg ctttaaaagc acattgcttt
    40201 tttgcagaac gccaaaaagc gtctctactt tcttgatgac tttgaaaaaa tggaaggggt
    40261 tgttttgctt gctggatagg cgaatacagc gacattttct gtgaaaagta aacttttttt
    40321 atctccatcg cgctctcctt tttcttcaag tataccagta cgtcataaaa aggtcatgag
    40381 tctcgtattc gactttgtag attccataag aaaacaattc ataaaacctc ctttaaataa
    40441 aaaaatacaa aaatcacaaa aattaattga aaatgagagt gttttcaatg aaaacgtgat
    40501 tttgtaatgg aattttaaaa taaaagaaac aagctttttt aatgcaaatg ttgtaaaata
    40561 aaagagatta agaggaaata agaggaggaa catgatgact gagtcagttt atgtacatat
    40621 tgataccaca agtaatgctg ttttaacaaa agggctgact gctactgact ttgcaaacag
    40681 tatcgtgcat tttcctcaaa acttgctctt gcttgatcca tctgcttctg ctggagaata
    40741 tgaatcccat acagggctga aagtaatccg tggtacagaa aatattcagc gtttcttttc
    40801 ctcttctcgt aacaggcgtg gattcgatga attgaagtgg atcgacttta ctgatttaac
    40861 gatgctgaaa gaattgacac ctttagaaat ttcagaatta ttatattttg gtcatatgaa
    40921 aacacatctt cattcgccgt ttttttataa actacagaat aattttgtat acttcgatct
    40981 taatgatcag ctgaatcgga tttattatcg ctatttagat gaattttata ggatttttgc
    41041 tagtaaatta agttcgatct tgtcagataa gatcaatgta aaaaaatctt ttttaaaaaa
    41101 agaaacacct gttgaaaaaa tcagtgtgga attattgaaa gaaatgcgta atttgatgca
    41161 ggaagggatc attttttctt ttgatcaagt tggtttgatc gatggtaaat atcgtatccc
    41221 aatctatgtg attgaagatt atatttggaa attaaaaggc acccggtatc gagaagagga
    41281 aatcatcgct actttaatct actctgtcac cgatcgacac tggcaattgg tagaagatgc
    41341 cgatctttct tatctgccat tgaagtagat ctatttctta tcaaaaaata aaaaggaaac
    41401 aagaaactag gacatgattc tgtctcaagt ttcttgcttc ttttttattt acagctcctg
    41461 tcgtttatct ggcacaaaaa tcgaaggagt cgtttgttgg atccctaata aaacgatgat
    41521 cgttacaata gctgtactca acccgctggc accattcatt acgaaagaaa agagccaagg
    41581 attcatcccc catagtgcat acgctcccca gaaaaccact cctgcaataa aatgccaaaa
    41641 atatctggaa agtgcgccaa tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt
    41701 attatcgtct acatagcctt tttggacatt tgaagccatg agccctgctg cgcctgcaaa
    41761 agtataggca atcgggtact caatcaacac ttgaacgaca cttaaataat aaacttgtcc
    41821 caacggaaaa tgtaggatgc cccaaatgaa acctgccagc atccctgcct ttgtccctct
    41881 tcttaacgca aaaagagtca atggaatctg ccctaatgaa atagaaaaac tgctgccgat
    41941 ctggatcgga atcaacgaca acaccatcgc taacgctgca acaatcgttc cttctaccca
    42001 aactctattt tttcccataa aaaaacttcc tcctttgaat aaaaaagtca caaaggagga
    42061 agcagctttc gaaaatagtc aaacagctgt ttattcacaa ttcctacgct cgcataaccg
    42121 atacaggtac gaagggttta gaaatagatt caatctcagc ccaattggac tcccctttgt
    42181 gagtttattt attatttatt ttttgtttca aacaatggac taactggttt gttttcatgg
    42241 atacgtttga ttgcatctcc cattagtccg ccaacactta cttcatcgat tttgtcgatt
    42301 ttacgatctt ctggaagata gatcgagtct gtaacaacta gacgctcgat agctgaatct
    42361 tctattcttt gtaaagcagg gccggataat actggatgtg tacatgaagc atacacacta
    42421 gttgcaccag cttctttcaa agcattggca gccaatgtga tcgtacctgc tgtatcgatc
    42481 atatcatcga tcagtacaca agttttgcct ttgacttgtc caatgatatt cattacttct
    42541 gcaacatttg cttttggacg gcgtttgtct atgatcgcaa tcggagattt caaaaattcc
    42601 gctaatttac gtgcccgtgt gacaccacca tggtctggtg aaacaacgac aacatcatcg
    42661 cctttgattc ctttttctaa gaaataattg gcaataagtg gcgcacccat caaatgatcg
    42721 actggaatat caaagaaacc ttggatttgg actgcatgaa ggtccaaagt cagcattctt
    42781 gttgcaccag ctttttgaat catgtttgct actaatttcg ctgtgattgg ttcccgtgca
    42841 cgtgctttac ggtcttgacg cgcatagcca taataaggca tgactacgtt gattgttttt
    42901 gcacttgctc gtttcagtgc gtcaatcatg atcagcaact ccatcaagtt atcattgact
    42961 gggctgctcg ttgattgaat aacatagaca tgcgatccac gaatactttc ttcaatgttt
    43021 acttgaattt ctccatcact aaattgagta acagatgatt ttcctaactc gacgccgact
    43081 gctgctgcaa ttttctctgc taatgggcga ttggaattta acgcaaaaat ttttaatctt
    43141 gggtcaaagt aatgttttga catggggacc tccactttct ttttcacaac tctagaattc
    43201 tacctaataa atagtagtca tattttttaa ataaatcaag tgattttgca aaagtcttag
    43261 tttagataag ggagtttttt tgcatatcct tctttattga cttgtcttgc tctcgcaatt
    43321 gccagcgcat attctggaat attgtctgta attgttgacc cggcagcaat cgaactgttt
    43381 ttagctacct cgacaggtcc gatgatattc gtgctagaac caataaagct gtggtcgccg
    43441 acagtcgtat gatgtttgtt ctttccatca tagttgacga agacaacacc acatccgaca
    43501 ttgatttctt ctcccagcgt agcatcacca acataagtca agtgaccgac tttagttcct
    43561 ttgccgattt gagcattttt cacttccaca aagtttccga tatggacgtt ttcgccaatt
    43621 tcagcttttg gtcgtaaatg tgcataaggt cccacatctg catgtttctt gacatggctg
    43681 ctttcaatga ctgagttttc aatgacgacg tgatcctcaa tcctactgtc tacgattttt
    43741 gaatgtgacc cgatgacaca atcagaacca atgactgtat ttccttggat ttgtacacct
    43801 gcttcgatca atgtgtctgg accgatttct acgcctgcat cgatgtatgt cgttgctgaa
    43861 tcgacaaagc ttacgccatt gaccatatgc atctggttaa ttcgctttct catgatctca
    43921 tttgctttag ctaacgcgat ccgatcattg actcccattg attcttcaaa atcatccgtt
    43981 tgataagcag caactgtatg gccttcttct tttaagattt cgatgatatc tgttagatag
    44041 tattcacctt gagcattgtt tgttccaact ttgcttaacg catcgaacaa agcttcgttg
    44101 tcaaaacagt aagttcctgt attgatttct tgtacaagag cttcttctgg tgttgcatct
    44161 ttttgttcca cgattttttc tacgatccca atatggtcac ggatgattcg tccatatcct
    44221 gttgggtttt ctgcttgtgc cgtcaagatc gttgcacttg cattttttcc ttggtgatat
    44281 tcaaaaagat tgttcagcgt ttcagtagtc aataatggtg tatcgccact gataactaac
    44341 gttgttcctt tttttccttc caagaaagaa gcagcttgca aaacagcatg tcctgttccc
    44401 aattgttctg cttgtaacgc atatttactg cgttctccta gttgtgcttt aacttgttct
    44461 gctccgtgtc caacgatcgt aatcacttca tctggtttcg tttcactgac ccgattaatg
    44521 atatgttcta ccataggttt accagaaacg ggatgtaaaa ctttatataa ttttgacttc
    44581 atgcgggtac ctttccctgc cgccaaaata attgcataac gtgcgtccaa ctgcgtcact
    44641 cctaaatata gtttgctgat ttcagtttat cccagtatac ccattttttc aacaaaacaa
    44701 gtgattttct tttatcccag cgttttctgg ataaaaaaat agatagacca taacgggcct
    44761 atctatttgg taaccggtgc tctcctgcca actcctcggt cacaagtcac actactcata
    44821 aaacatgaaa agctgttttt tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt
    44881 acaacctctt cattaaacgt ttttcaatca gctgaccttc ggtattagct caataaacgg
    44941 caaaatatga ggagcaattt ttccgtttat tgagctaata ctcaggacag gacgctgatt
    45001 tcacaacctc tagataaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat
    45061 gaaaaaatgt ggaaagccat tttcacaaaa tttttcttac tactcgaaac taagcggctt
    45121 tttcacaacc tcttattctg aaaaataatt tcctggcaca accgtaatat ttttcgtttg
    45181 agtatctaca tctttgacat aaagcagtga cgtataatca tcgatggcgc gatgaccgtt
    45241 gaattttgat tcggcaaata cagtgatgcc aacaagttct gattcgaatt cttcaatcaa
    45301 gctcttcatt ccgttgactg ttccgccgcc tttcatgaaa tcatccacta caaggacacg
    45361 tgaaccacgt ttcaaacttc tcttagacag ttccatcttt tcaattcttt cagaagatcc
    45421 agacacatag ttgacactta ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat
    45481 aacgaatggc gcattcagat aataggacac agcttgggca ataggtacgc cttttgtggc
    45541 tacagtcatt acagcatcga ttttttcacc aaggtattta gaagcaatga ttcttccaac
    45601 ttgacgcagc agttcaggtt ctcctaacaa atcagagaga taaacatatc ctcctggaag
    45661 cagacggtct tgttctgata gacgttctgc tagagattca atatattttt tcgcctcttc
    45721 atatgaaatt tcagggatga acaatacacc acctgcagca cccgggattg tttccaaggt
    45781 tccataccct cgttctttaa atgttttctt gatgattccc aaatcttcac tgatagaaga
    45841 tttagcagat tcataacgtt cggcaaagct tgttaaggaa atcaattcat gcgggtgatt
    45901 caataaatac tgtgtcatgt caactagacg ttcactgcga cgtactttca cctattccaa
    45961 ctccttttaa gaaattttat cgttttacat tatataagtt tttcttcaaa aattcgagca
    46021 ttttatgaaa aaataagaaa atagttcggt atttattaaa ataaaaagaa gcctataaaa
    46081 aatttttcgt ttttataagg cttcttttct ttataattta gttatttttt cttctgaagg
    46141 caaccaatat tcgtttgatg atatttacaa tcaggaacaa agcaataaag actaatgtga
    46201 ttgttgctcc tggaggtgta tctagataaa acgagctagt tagtcctgac agcatcccta
    46261 gaaatcctac acaaacactg atagcaatca cgacattgaa gcttttgcct aatcgcatac
    46321 cgattgctgc gggaagaacc atgattgcgg atatcaaaag tgcaccggca atcgggatca
    46381 tcacagcaat agccacacca gtaatcacat tgaacatcat cgacatcaaa tgaacgggta
    46441 gcccatccac gtgggcggta tcttcatcaa aagtcagaac atacatcggc cgtttgaata
    46501 aaaagaacaa tataccgatg gcaacgaata agattcctaa aaagatgact tgctcccatg
    46561 taatggtcac gatcgaacca aacagatagg attggatact tgttgctgaa ttccctccgc
    46621 tcaaattcat caatactaac gctagcgcca aaccaccagc cattaaaatg gcaatggaga
    46681 tttctgaata ggttcggtag atcgttcgca gatactccaa tatcacagct gctaatacaa
    46741 cgactagcat ggtcgtaagt gtaggattaa ggttcaaaaa gaatcctaac gctacccctg
    46801 ctaaagagac atgagaaagc gtatcagcca tcagcgattg tcttctgatc actaaaaaca
    46861 cacctagcat cggggcgatt ccggcaatga agatagcggc aagaaacgct cttctcatga
    46921 attcatatga aagcaacgcc attgagaatc ctcctttctc accagtcgga tctgtctgtc
    46981 cgcatactgt ttgatatctt catgatcatg ggtgatcatt agaactgatt tcccatggac
    47041 atgcgcacta tgtcggagaa gacgataaaa ttcatttctg gattcttcat ccatacctgt
    47101 tgttggttca tcaagaacaa ataagtcagg gtcagtagca aaaatacgcg ctaaactgat
    47161 tcgctgcttt tgtccgccag acaattcacc tattcgccga tttcgcatat cccacatccc
    47221 tacagcttct aaagcacgct gtacatgttg atgatctttt tcagagagac gcttgaacca
    47281 gcggcctctt ggatatcttc ctgaacggac taattcgatc accgtactag gaaaacctgc
    47341 attgaaagat gcaacttgtt gaggaatata accgatactt aatttttttc cttcttgatt
    47401 tttctcagca atctttatca ttccttttga aggtttcagt aatcctaacg atgctttcac
    47461 caaggttgac ttggctgctc cattttctcc agttaaaatg acaaattcac ccgcatctac
    47521 atgataagag acatcttcta gtacaggttc atcatcatag taaaaggtca aatcagatat
    47581 ttcgatataa cgcaccttac aacctccatt ctaaaactta attgatactt tcttttaaag
    47641 ctttcagatt tttttccatg acagaaatat aattttcgcc tgctttgatt tgttcattag
    47701 tcaagctttc taaaggattc aacacttcta gcttcactcc tgtttcattc gacaatgtct
    47761 cagctacctt cgaagaggca ttttcttcaa aataaatcac tttgatgttg tttttcttca
    47821 caaattcttt tagctcagct aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg
    47881 aaatcgctac ttgttttaag tcgtattgat tcgctaaata agcaaaagca gcatgctgag
    47941 tgacaaatgt gcggtttgtt gcatctttta gctcatcgga gtatttttga tccagtgctt
    48001 caagcttttt gatataagca tcggcattct tcgtaaaagt ttccttttta tctggatatt
    48061 tttcgcctaa ttcttcagca atcgttctga cttcttttat agctaatacc ggatcgagcc
    48121 aaacatgtgg atcgtattca tgtgaatgac catgcccttc ttctgattct tcatgttcgt
    48181 ctgcttcttg cgattctaaa cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt
    48241 tgctatccac tgaatccttt aacgaatcca caaaaaattc catgtctgaa ctattataca
    48301 cgaaaacatc tgcatcggaa atttctgctc tttcttttgc acttggttcg aaatcatgcg
    48361 gctccgttcc agcagggatc aaaagtttca cgtttccttc atcccctacg atctcttttg
    48421 taaaatcata catcggataa aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt
    48481 ccttgttcgt atttccacat gctgcaaaca gtaaagcacc tatcattacc gtagctgtca
    48541 aaagatattt tttcatttat atgctccttt caatgaacaa atcggaattt tacgatttat
    48601 taacgtgaac taatgtatca aaataaaaaa acacagtcaa tagaaatcca tcaatttctg
    48661 atttaagcat gtatattctt gattaaatcg taaaatggat gagttgctgc tcatatctag
    48721 ccatttcact acaataaaaa actgaagaat accattttag gattcctcag tttttcatca
    48781 cctattttac ttcttatatt ttattgcagg gttcgtacta aataaacttc ctcacaaaaa
    48841 ccttttaacc cattatatac tctctgcgct cttgaataat gttgacacaa ggcaaaaacg
    48901 gttggtccgc ttccactcat caatgcagca tctgctccgt acttgatcat acgctctttg
    48961 atttgatgga tgactggatg ccgctttccc gttatatctt ctaaactgtt tcccattttt
    49021 ttgatcatct gctgataatc ttgctctcgg atggcttcag caagtccgtg gatgtcttga
    49081 tgttggatgg cttgcgtatc tacttctcta aacactgtac gtgtagagac actcattctt
    49141 ggtttgacca acacaaccca gcactgtggc atagaaggta atacttggat ttcttcccct
    49201 ttgccaccga caaatgccgt acttccgtag acacagtaag gaacatctgt accgacttcc
    49261 aaaccgattt ctgccagttc ttctaacgaa cagcccagat tccataattg gttgatccct
    49321 cttagagcag ctgcacagtc tgtacttcct ccgcctaatc cagctgctac tggaatattc
    49381 ttcttaacaa agatcttgac accggttttg atattgtatt tattttttag caataaagca
    49441 gcttgataaa cattgttccg ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg
    49501 attttgtctt ctgttatttc ttcaaaaaat agatgatctg ccaagtctac gctcgacatc
    49561 accatttcca actcatgata cccatcttgc cgtctatata atacatccag tcctaaattt
    49621 atcttggctg gcgctttttc aatcaattcc atcctctcac ccattcgaaa agtctaagtc
    49681 gcaagtattc tatcataggg aaaaataaaa gtatagctta tgtctgccta gtggttgatt
    49741 ttgtcatcgt ttcaacagct ttcacagaat tttctcttca taatccaaac aagttctagt
    49801 gattcttata attctgtgag cacttcttct gccaaactcg gaacatttcc tttttctttt
    49861 cctatcagac tgagtagctg catggtagca aatccgaaat tacttccttt cctataagca
    49921 aaataacgtc cttcccaatg atcgacatat tttaatttct tttcataagc agactggaag
    49981 gaatagaaaa aattaccata attatatacg atatgcatga ctttttcttg aaagaaagaa
    50041 aaatctgttt ctccaacatt agctaatgga gctaagccta gattggcttc cgagtagccc
    50101 attttctcgt atacaataaa cagattggct aacagatagt cagctaattc ctcagattct
    50161 ttaggtaaga cccgcaacaa atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg
    50221 atgaagccaa cgactttttg atctttacgg acaataccga caccgctaga taatacatat
    50281 gatttatcaa atcgtcccac agagaagtat ttttctcgtg caccttgaag ccatttttgt
    50341 gaaacttcat ttacagcttg atgtaattct tccggcagtt gatcgtacca agtaaaatgg
    50401 tatccttctt tcatcaaacg ttgatattca agttgctgac tcagccgaga caagtcttct
    50461 gttgctagat caacaatccc tgcttcacct actttcgtga agtgaaaacc caattcatga
    50521 agcatcacta cgtagctttc tgatatctta taaaacgcaa gctgatagcc taaacaatct
    50581 gcttgtttca taaactgatt cgttgctgcc cgcatcattt taggattgcc aactggatct
    50641 cctaaaacaa agcatttgtt tcctttgatc tgataaccaa aaacgacttg atcttggtcg
    50701 tcttcttggt aataaaaata actgtaacct gacaagcgaa gctgatggct tgtagctgtg
    50761 cctccgtatg tttccaataa acggtcaaaa cggtcttttt cgtactcact gccaagcttc
    50821 gtagtatctt cagctaaata ttgataaagc gccactaaag ctagcaatga gatgcccaaa
    50881 ccaataagcc ctgagaacca cacatcatct gaaggaaaca aaataaaatg atttcctgtt
    50941 attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa
    51001 aagccgaaca agctagcatc aaagattata gctccccaag aataaacgaa ttttgttcga
    51061 taaaattctt ttctggataa ccacacagct aacagaatca agacatatac caatatcaac
    51121 tgccaagata acgtacgtgt gattgtattt aaaataccaa aagatagtaa agcaatcgta
    51181 ggcagaaatg cctttttgac ttttactgaa agtgctctag caaggccgag taataaaaag
    51241 ccaaccaata gattcactgt ctgatctaaa aaattgaatg agaacggcaa taatacttga
    51301 aatagccgac tgattgcaga cagattagtg attgttgata gaagtaccat catgatcccc
    51361 gcaaaataga cagcacttac gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga
    51421 atgttatcta aaaatcgatt gattttgact cctgtatgtg tgatgaacaa tagaagtccc
    51481 gtcataaaag gtagaacata ataaaacaac cgataatata atagccaaac tactgctaca
    51541 tcttgccgaa cagacaattg actcattcct aagatcatca aaacgtcaaa agtccccatt
    51601 ccacctggga ccatcgtcag cattcctatc aatgtagcaa tcatgaacat aggatagatc
    51661 gaaagcatcg aaatatctat tctcatcaac ttgccgatga tcaaaaatac cgcaagggct
    51721 cccgtccatt gtccaaagga tgccagtagc agaccaagca agccttttgg ataaaactcg
    51781 aagaacaatg tctttctctt tagataagca aaaaagaaaa tgactggtgc taaaaaacta
    51841 ccgccgaaaa gccagatcca atagcttcga aaaatacttt ctgactgaat aaaaaagaca
    51901 tcaataaatg taagaaacga ccatacagac aaaccagtca gcataaatag tgcgactttt
    51961 gatacagtgg ctaaaaccat ttttctattt gtctgctttc cataaaaact agcccgcaga
    52021 cttgctccta ccacaccacc aaaaccggcg agattgttga tcgtgtttgt tacccacgca
    52081 gcaagaagaa actcttttct ttccattttt ggttttcctt gtttttctaa gactctgatc
    52141 gtcacccaat catacaacaa catcggagtg acacccagca gtccagccag aatcatgagc
    52201 aggatcgtca tgcggctttg ttgtcccatc ctttgccaaa tatcttgcca actcatgcca
    52261 ttagcaatat ttgcgacttg atttgccaca aagactaaca cggagccgaa aaaaatcagt
    52321 tttaaaatca gactatgttc ctttatccat tgcagcatca agtatcgttt atttttcaca
    52381 ttttcccatt cctaacttgt atacttttgt gtcatacccc aatgttatct tatttatttt
    52441 aatttttcca ctttagacct gttctttgct tgcgatgata gaaaaagaaa gatatcctaa
    52501 tgctaaagga gaggataaca tgaaagtagg atttatcggc acagggaata tggcacaagc
    52561 tattattgat ggtttattaa aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag
    52621 tggacatttt gaaaatgcac aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag
    52681 taatcaggaa gttgcatcac aatcagatat cgttctttta gccgtgaaac caaaaatcat
    52741 tgaaaaagta ttggaagaac taagagaata tagccagaaa gtcttattca tttctattgc
    52801 ttcaggaaaa tcattaatag atttagaaac agcgcttgaa gatcctcagg cctccatcgt
    52861 acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa
    52921 tgaagctgcc acggaggaac agcttcagca agctacgatg atttttgaag caatcggcag
    52981 cgtctatcct ttagcagaat cagatttcag tacattcatt ggccttgctg gcagctcacc
    53041 cgcattcgtt tacatgctga tcgatgcgat gggacggact ggtgtactga atggtttgtc
    53101 caaacagaca gccactgaga ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct
    53161 ttcaagtgat aaaaatccat gggaacttgt agaccaagtt tcttctcctg gcggtacaac
    53221 tgttgcaggt gtagttgcct tagaagaagc aggattcatc ccagcaatca tcaaaggaat
    53281 caatacgacg atcgagaaag atcttgagat gttgaataaa aaataatgat agcaatgttt
    53341 tttcgtgcct tacaaaaaaa gaagagctgt ggcttttgcc gcggctcttc ttttgtattt
    53401 tttattattt agcataatca gttgcacgag tttcccgaat aacgattact ttgatgtgtc
    53461 caggataatc cagttcttct tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt
    53521 ctaaatccga gatttcttct ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg
    53581 cgtaacttga ttctacaccg gcgaagctgt tcgaaatatt ttccagactt cttaaacgac
    53641 ggatgtagtt ttctaatgat tcacttcgcg caccaggtct tgctgctgag agcgcatctg
    53701 ctgcagctac aaggacagag ataacagaag tagcttccac atctccatga tgagaagcga
    53761 tcgcgttgat tactactggg ttttctttgt acttggcagc taattccgca ccgatctcaa
    53821 cgtgagatcc ttcaatctca tggtcaagtg ctttcccaat atcatggagc aacccggcac
    53881 gttttgctaa ttggatatct tcgccaagct ctgctgctaa gataccagct aattttgcaa
    53941 cctcgaccga atgcttcaag acgttttgtc cataactagt tctgaatcgc agacgtccga
    54001 tgatcttgat tagatctgga tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc
    54061 cgtattcgcg aatacgttca tccatttctt tacgagattt ctcgaccatt tcttcgatac
    54121 gcgctggatg gattcgtcca tcttgtatca gtttttccaa ggtcatccgt gcgatttctc
    54181 ttcggattgg atcgaatccg gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat
    54241 cgataccagt cagcgtctca agcgttcgaa tattacgacc ttctcgtcca atgatacgac
    54301 ctttcatttc atcattcgga agggtaacga ctgaaacagt cgtttctgaa acttgatctg
    54361 ctgcgcagcg ttgaatcgct aatgataata agtttttcgc tttgcgatct gcttcttctt
    54421 tggcacgctg ttcagattct tttaccatta gagttaactc atgattcagc tcttcttcag
    54481 tcgatttcat gatgacatct cgtgcgtcct cttttgataa accagcaatt ttttctagtt
    54541 ctttttgttg atcttcaatc attttttcaa cgtctttttc tcgctcttca attaattgct
    54601 gttttgaact aagtgcttct tctttacttt caagtgagtt ctcgcgtttt tctaacgagt
    54661 catctttacg attcagcgtt tgttcgcgtt gaatcaaacg attctcttga gattttaatt
    54721 ctaacttact ttctctcagc tcactttcaa cttcagaacg gtatttctga ttttcttcct
    54781 tagcttctaa caatgcttct ttttttagag tttctgcttc tttttttgca ctatcgatga
    54841 ttccagcagc tgatgattgt gcaccagcta tttctttctc gtgacgtgac tttgcgacca
    54901 taaaccctaa accaagaccg acaattaaac cgatgatagc gaggagaatg ttgaatacca
    54961 taaaatccac ctccatacta tctttttcat ttttatcatc tatacagctt ctatgataaa
    55021 ttattctaaa ctcgtcaata tgcatcttcg catatatgtg tacaaaaaac atgcacaact
    55081 ttattctaat gtttgtaccc cgtagtgtca actttaaata aacaaagaaa cggctttcta
    55141 cttattcatt aaacgatggt ttttaaaata aatgacacta gtttcatata ggtaaacctt
    55201 taaattgaga aacttttcta ttaaattatt ctttgtagat gaacagatat ttttatttta
    55261 tgtacccact cgtataatta aataactcac gatttcttta ttcaataaaa aaacggcagg
    55321 tcaaggagag tacctactct tcagaccagc cgtttttgtt tatcataatt tttattcttc
    55381 tactaaaggc aattcttctt gtcctttttc atcttctggg acagcgactt cttcaccaat
    55441 accataagct gctctaacta gagcagaaac ttctgccatc atttcaggat gattagccat
    55501 atagatttta gcgttttccc gtccttgacc aatccgatct tctttataag aataccaagc
    55561 accgctttta tcaacaatgt ctttttctac tgccatgtct agaagttctc cttcttgtga
    55621 gatccctaaa ccatacatga catctacttc agcgattttg aaaggaggtg ctactttgtt
    55681 ttttacgact ttgatctttg tacggttacc aacaatatct gtaccttgtt tcaattgttc
    55741 tgcacgacgt acttccaaac ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt
    55801 gatttctgga ttcccaaaca tcacgcctac tttttcacgg atttggttga tgaaaatagc
    55861 gattgttttt gttttgttga tcgaaccaga gagtttacgc aatgcttgag acatcaaacg
    55921 tgcttgtaac ccgacatgtg agtcacccat ttcgccgtcg atttctgctc gtggaactaa
    55981 agcagcaact gaatcgacta ctacgatatc tacagcccca cttgatacta aagcatcagc
    56041 gatctctaga ccttgttctc ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac
    56101 acctaatttt tgtgcatatt gcggatctaa cgcatgctca gcatcaatga aagcggccgt
    56161 tccgccattt ttttgtactt ctgcaatagc gtgtagtgca actgttgttt tacctgaact
    56221 ttcaggtcca tatacttcga tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac
    56281 atctaacgca agagagccac ttggaattgt agagatttgt tggtcgattt tttcgcccaa
    56341 tttcataata gagcctttac catagctctt ttcaattttt ttcagtgcag catctaaggc
    56401 tgctttacga tcatctgcca atacgataat cctccttata tttacaaatc agagcaacat
    56461 ttcattatcc ttatcatatc ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat
    56521 tcgcatttat cattttctta aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc
    56581 attatatctg atagcagcac gatctctggc aaagtgatat ttttccgaaa ccacgccgtc
    56641 tttagatgaa atagcgatcc atactgttcc tgcagattga ccttctaacg tgtccggtcc
    56701 agccactccg gtgaaagcta cactgtaatc tgttcttgct atctcacgtg cttgaatggc
    56761 catctgctcc acacattctt tgctgactgt tccatattct gctaatagct ccggatcaat
    56821 ctccagaaaa ccagcttttg tttggagcga gtaggtaacg aatccgcctg gaaatacttc
    56881 agatacacca gcaatgtcgc ctaatgcggc ttggaaggcg ccggctgtca aactttccgc
    56941 tgctgttaca gtctgcttgt tttctttcag tagttccact acgacttttg ctagcgaatt
    57001 atcatcgccg tatccataaa aatattcccc tactcgttct tggatttttt cttctaatgc
    57061 taaaagagct tgattccctg cctgaacatc atttgttttc actgtcagtc gtaatgtcac
    57121 ttcatttggt ttggcatatg gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt
    57181 tagctcagtg accagtcgcg attcaccaat cccataaaag cgcaaaactt tagaaattag
    57241 tttttcttca gaaggaaaac gttcctctag taaaggacgt acttgttcca caaacattgg
    57301 tttcaactca ttaggcggac cgggaagaag gatatacgca tgtgtatctg tttgataaaa
    57361 agtccctaaa gcaagccctg tacgatttgg tagaggaacc ccgccttcga taatctggga
    57421 ctgttgcaga ttgtttttgg tcatttttcg atgggttgtt tcaaaatatg ccaataattt
    57481 tttgtatcct tccgtatttt gtatgagaga cttaccgagg tgagccgcag ttgcttcttt
    57541 tgtcaggtca tcttctgtcg gtcctaatcc gccacataag agtatgagtt cacttcttgt
    57601 ttcagctaga gcaatcaact cttctaaacg ctgctgatta tctcctacaa ctgtttgata
    57661 ataaacttcg atacctagat cagctagctg ttctgacaag aaagtggcat tcgtattcac
    57721 gacttgtcct agtaaaagtt ctgttccgac agctattatt tctgctttca ttacttcccg
    57781 ctcccttata tagtatacgc tgtattttta tattttttta tttaaaaaga gggcaaggag
    57841 ctgtgacaaa aatcttgtca cagctccttg ttccaaataa acagtgttct cctgccaaaa
    57901 cctcggtcat aagtcacaat atacataaaa catgaaaagc tgttttttga aattatccct
    57961 tgtgactcag agttagacgg caggctcaca acctctccac taaacgatac ttacattgat
    58021 cctttgaaca caccgctgtt tttgatgaag taatccacac ctgaatagat agtaaagatc
    58081 agacaagcat aaagcatgat ttgatctact ggaataccga tcaggctgaa tgggatatta
    58141 ttgataaaca gcaagataat agcaaccatt tgtgtagccg tcttgacttt tcccggccaa
    58201 gctgcagcca tgacttctcc atgttcgaca agtagtaaac gcaagcctgt gacggctaat
    58261 tcacgacaga caatgatcgc tactacccaa ccaggggcct ttccttggtc aaccaacatg
    58321 ataaaagcag tcataactag cattttatct gccaacgggt ccgcaaactt gccaaaatta
    58381 gtgacaaggc ctcgcgcacg ggcaattttt ccatctaacc agtctgtgat actagctaaa
    58441 gcaaaaataa ctgcacctac tagctgtgtg acagccagtg tggtgtctcc tacgttaaat
    58501 tgtccccaat ctaaaggtaa acctacaacc aaaatgaaaa tcgggatcat acaaattcta
    58561 agtacagtta atttatttgg taaattcaca ctatcgactc ctttcttccc tattctacgt
    58621 gactatcagc gaagtttcca ccgatattat ttacttttcc aaatgaattt attcaaagga
    58681 gtatttttat tgaaattgat ctttttgaat taacgaagaa ggaccgcgac acagatttgt
    58741 cacgatcctt cttttttata cctacaagta aacagatgcg taaactaatt tatacgatca
    58801 ttctgcgtat tgaagagtaa ggttcacatt ttttggactc tgattgtttt cccctggatt
    58861 aactggtacg gattctccat tcgctttgat cgttgcattg cttgctgcac caatcgtgat
    58921 ggtcgcattt gttgctgttt ccggtaacac ggtactctgt gtttcatttg ctgccagtgt
    58981 cccttgataa acataggcat tgtctactag cacacctaac catacacgat tgacagcagt
    59041 aaattcaagg gttacaggct tggtagcgtc tgtgatattt actgcgatgg cactgccaga
    59101 atcttctcct gtagctattg ccattttctt ttcttcactt gattttgttg ttgattctac
    59161 tgtagaagac tctttggtct gcgtgctttg ctctgaggaa gaggactcct cgactgatcc
    59221 ttctacttta agcgaagaag ctgtgtctcc gattattgga tcagcttgac gatcttgcca
    59281 agtcatatag cccacgacaa cgacaatcgc caaagcaacc aatcctaata aaatgacagg
    59341 aagacttgtc caaaagcgac ttggatgcga ttcttcctga tgcattgctt ttctagaagt
    59401 acttactgtt tcaggctgcg gacgttcagg gaccgatcct gtcaatttgc ttttcccatc
    59461 aaaaacatcg actaaatggt ctccatcttc tcctacagct tcagcgtatt gccgaataaa
    59521 tgcccgcacg taaaatttac caggcaattg gtcaaaatca tcattgtcga ttgcttccaa
    59581 ataacgtttt tgaatttttg taatctgctg taattcatct aaagatattt ttttattcag
    59641 gcgtgcttgc cgtaattttt ctccgatggt ttcaaaagcc actcgttcat cttctccagt
    59701 ctgtttgatt ctccgaagca tctgctgttg caacgaaaga cgttatgttt gggtgctgtg
    59761 acaaaagtca tgtcacagct ccttttttcc gaataaacat tgttctcctg ccaactcctc
    59821 ggtcacaagt cacaatatcc aataaatata agaagctgtt ttttgaactt gttccttgtg
    59881 actcggagtt aaacggcagg ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc
    59941 ctcggtatta gctcaaaaac cggcaaaata taaggagata tttttccgta tgtttctcta
    60001 atactcaggt caaaacgctg atttcacaac ctcttcctta aacggtgttc aaaagcttgc
    60061 atctgcggta ataagtccaa ccaagttaaa aacattaaga agctgttttt acttggctgt
    60121 tcttattact tgatgcaggg cagctttttc acaacctctt ggtacacggt gttccagaag
    60181 tagcttcttc ggcaataagc cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt
    60241 ccttcttatt tcttgaagct gaccacttct gtcacaacct ctttgattac ttcgtttgat
    60301 tttattttaa tataagttga ttaaaagaga gcatgatttg ttttattttc tcactaattt
    60361 ttccaacaca actaagaata ccataaaagc tgattttgga ggaggttcct actacaagtc
    60421 taaaacgaaa tttaagactt ttcctcataa aatactggtt tattttggtc tcatgtaaaa
    60481 ctcgctgaag gcctcttcac ttataaatgc ttccccagct gccagtacgt ctttcatttg
    60541 gatcgaatcg atgatttcag gaagatcaaa taaagttcga tcgccaaata aactttgcgt
    60601 aaattgattg gcaatatatt cgatcgaatt taatgattgg aaatattgtc caagcatttt
    60661 cttcttcagc aaatcgagat ttgtttctga cacttccgga tcatcagcga atccaagaat
    60721 gatttctttg actttttctg ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc
    60781 aaagtgaaat tcacgatcca agctgaattc aaaaccaaag ctgtcatcga taattccttg
    60841 attgtacatc gctagatagt ttcgagaagt attgcctaaa atcatttgga acaacagatt
    60901 gattgctgtt ttatagcgta acagttctgt tccttcttgc ggcaatgtgt ctaatccttt
    60961 aataccaagt acaaatttat ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat
    61021 ttcttttgtg ttttcaggga aataacgtac aatttcttgc tttggaggga aattttttgc
    61081 ttcttggttt tcccgaataa gtttcatcaa tttctcaggc tccatcttac caactacaaa
    61141 taaaaccata ttgcttggct gataaaacgt ccgatagcac gtatacaagt cttgagctgt
    61201 gattttgtcg atactttcaa ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata
    61261 caagttattt agtatgccaa aaaacatccg ccagttaggg tcgtcttcat acatttggat
    61321 ttcctgaccg atgattcctt tttccttgtt tacagtttct tctgtgaagt aaggtgcttg
    61381 tacaaaatcg atcagagtcg tcagattctt ttctacctga tccgtcgtag aaaacagata
    61441 gctggttttc gtaaaacttg tgaaagcatt ggcggaagct ccttgtttcc caaataattg
    61501 aaagacatca ccatcttctt tttcaaacaa cttatgttct aaaaaatggg caattccatc
    61561 tggaactttc accttttctt tttcaccata gggaataaat tcgttatcga tcgaaccata
    61621 attcgtactg aacaaaccat atgtcttgtg atagtcattt ttaggcaaca aatacacggt
    61681 caaaccgttt ggcagtactt catgataaag tgtttcattg atttgctcat attctgtttt
    61741 attcatttgc atttcctcct gctaaaaaga agattgcctg caattcgatt tgctcagcta
    61801 cttgttgtat ctctttgatc gttacgctct ccatacgttt caaccattct tcatcagata
    61861 attttgtttc cggcagccag ctgtccaaaa aagaagcttc gattgccgct tgcggagagt
    61921 ctagagaaag cagatattgg tttctcagca ttgcttttgt ctgagacagt tccaactctg
    61981 ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat cagatgaagt acttgatttc
    62041 ggttcttttc atcgataccg gtttggacac tcatgaatcc tcggaacgta tccacgctac
    62101 tagaggcata ataagctaga ctttctttct ctctgacatt catgaaaagt ttagagtgag
    62161 gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat
    62221 acacatttgt ctgataagct aggttcagct ttgcttgaac gattggctca cgtacttgtc
    62281 gttccttcac gatattcact tgaggttggg tataaaacag atctggataa actgtttccc
    62341 gcgactcaaa tggtaattgc ccaactgctt cagctgcttt gtccggatca acatcgccga
    62401 caacaaaaat gtcgatttga tcatttgcca tcatttcttg atagtaggac gctagcgaac
    62461 tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc tgggatcttt tgttccgggc
    62521 tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa agtttgttta tcttccttca
    62581 aactttccaa atatagacgc agattgttct tttccaagtc aaacgtcaac tgatcaaact
    62641 gatgattttt aatatttgga taaaataaaa cctcttttaa aaaatctacc gcttgagaaa
    62701 aaaggtttgg atcattgaca tattcaccat tcacaaaact gatccctgcg tttagccaat
    62761 gtaaatttcc tttttttcta actgataatc caaagcttgc gccataaagc tctgcaagtt
    62821 gcgcacttaa ctttgtctga tccgaataat tcaaactatt tgtttccaac atgctgctga
    62881 gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc
    62941 ggatcgtttt gtattgtttt gttggtaaga catgaagatt cacgccttct gccaattgat
    63001 acaccatatt tatatgctcc ttttcacagt tgattgcccg cttactcttt taatgggtca
    63061 acctgccttt tttacttatt cctctgcttg aaatttataa gttcaggcaa ttcgccgttt
    63121 tttctaaatg atgttacact ttatagtata gcatagatgt tttttatcaa aagaaacaga
    63181 cggctaaaag cgtatattgt ttttttattt tttatttttc gatatactaa agacaaataa
    63241 aagaagggag ggtcattcat gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc
    63301 ttggatcttg ctgtcggcgt tgttattggt agtgcgttta caagcatcgt aaaccaagtg
    63361 gtgcaaggct tgatcacacc actaataggt tggtttgtcg caatgatcac aggtacttct
    63421 gatttagaag gagcactttc aattcttgac tggtcgccga caaaaggcgt cacatttgcg
    63481 tttggtaacg ttattagtgc tatcattaca tttctgatca ctggttttgt cttattctta
    63541 gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca aagaagagca agtggaagtg
    63601 gaagaaactc ctactgcaga agattatctt agtgacatac gcgatcttct tgccaaacaa
    63661 gtggcagaag acaatacaca tccagtagag caaacaaatc tttccgatac ttctaaataa
    63721 taaagaatct aaaaaaaaga aagccgattt tcagtgtcgg ctttcttttt ttagattctt
    63781 aacttgctac ttgttccttt ttcatgtcga tatgtggaat atcatcttcc aaatacacat
    63841 ctgagattgc cttgaatcca aacgactcat aaaaagcttg taggtattct tgtgcgccga
    63901 tcacgattgg tttttctgga aaatttttct ggatcatgtt aatcgtttct tgaacaatct
    63961 ttcttcctaa accatcttta cggttgtcct gatgaacaag gacacgtcca aaatggatac
    64021 tctccgcttc ttcatatact cgcgtgtagg caaggatctt cccatcagta tcttgaaaaa
    64081 acgtatgcca agcttctcca tcaatgtcat caacttcttg ataaggacac tgttgttcca
    64141 caacaaaaac tgcgattcgt tctttgacga tcgcgtaaaa ctctgctgtt gacaattctt
    64201 caaatttctt tacctgatat tccactaagc aaacgccccc tgctttttta ttcttagcat
    64261 accgattcgc acacaaaaaa gcaaacgaac cttacgaatc tcaggctcgt ttgcttttta
    64321 aactgcttca gttaaaaatt cgatctcaac tgtccgagta agtacatctg aatagctgta
    64381 agatactcgt tcaaaagaat tttcttcagg atccaaatca acaacgaata ctgaaggata
    64441 ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa
    64501 catgattggg ctgccgatac gaccttctaa atctttcttg attgaagcta aagttgttgg
    64561 catacagttc acctctacta tcaactatac cacatatttt taaaattttc aagtttacca
    64621 taaaaaaaaa gaaatgcaat aaaaataaat aagaagctca ttaagatttt tctaaattat
    64681 tcctcattat aaaatttcaa gtgttttttt attttgagtt ttactctccc gtaagcgctc
    64741 attacttgct tgtgatccat tgctaaacat tcagccatgt ctacaaaatc aacgccttgc
    64801 atataataat gaaaaatttt agcttctatt tttgaaaact ggatttcgca attttcgatt
    64861 gcttctttta ataaaagatg ctgaattgct aaaggttctt gcaatgtgat ctctgctaaa
    64921 aagtctggtc cttctgtctc tattttttgg tcgattgaga cttcatcttt ttgatcacga
    64981 cgcttcagcg cgttctgctt cctcaacaga gaatagattt gattgcttat aacgctttta
    65041 taataacttc caaagctaac acctttgctt ttttcgtaag ttctcaatgc ctgatataaa
    65101 gcgatccttg cttcttgttc ccaatcctca gaaacataat ttcttaaata ataggtgttt
    65161 ttcaaacgta gtaaaagtgg aaaatatttt tgatacaggg cagcaaatgc ttcttcgtca
    65221 ccattacgtg cagcgcgcaa taactcctca gacataaaat aattcctcca taaattcgtt
    65281 tatggaggaa tcttatcatc aatgattcat cgaactgatt agaacgatat gttatttatt
    65341 ttttctcatt aaatcgtcca atttttggga caattttttt aactgctctt cattccatgg
    65401 agaattacgt cggaaatcaa taaaatgcat atctttattt tcttgggcta ttgttttttc
    65461 cgtttttttt atcgtcttat ataattcata agcagaagtt cgtaatgctc cttgggaaaa
    65521 gatcatccac tgttctgcta aatcgcttgt cgccactgtc acttgtgtca aacggtcatt
    65581 cagctgacca gcgattctct cgatataact gtcagccgtt tcgtcttctt tcgtaaaaac
    65641 aacatccaac tggtatttct tataattttg ttggatgccc ggaactagtt gggcatcgaa
    65701 gacaacgatg acttccattc cttcatattt cgcataattt gataaacgat gtaaaagagc
    65761 ttctcttgca tccgccattt tgtcctgctt tttaagctgg acaagttccg gccacgaacc
    65821 aatcatgttg tagccgtcta caatcaacag ctgttttttc atggtctact ccccctgacg
    65881 ttgggaaaaa gcctgataca taagcaaacc agcagcaaca ctggcattta agctctggac
    65941 gtgcccggtc atcgggatcg tcagcaattc atccatttct tttttcaatc ctggactcat
    66001 tcctttgcct tcattaccaa tgactaaagc aattgatcct ttggcattcc atttttggaa
    66061 gtttgtgccg gtcatatctg tgccaaatac ccaaaatcct gtttctttga gctgttgcac
    66121 agcttgtacc aaattcgtca cgcgtgcaac agggacatgt tcgactgccc cagtggaagt
    66181 ctttgttacg ataggtgtga ttccaactgc tcggtgtttt ggtatgatca caccatcgac
    66241 gccacttgcg tctgctgtcc gtaaaatcga cccaaaattg tgtggatctt cgatgctatc
    66301 caaaatcaaa aagaaggggt cttctttttt ctcttttgtt cgttcaatca gttggtcaag
    66361 ggataaatat tcataaggtg taatcgcaag aacgactcct tgatgcacgc cgtgatcgct
    66421 caaagtttct aatttttgtt taggaaccca tttgactggc acagcttgtt cacgtgcgat
    66481 ttctttcagt tcttctactt tttctcctcg tgaatcttct tgaagaaaga gtttattccc
    66541 tcgcccttgt tgtagcgctt ctactgcggc atggtgccca aagacgaaat tatcttctaa
    66601 tgcttcttca ttttgatcag aaactgactg atttcgtcca gtttgctttt tatttgaata
    66661 tctattttgt tttttgtctt caaatccacg tttcgattga tgtttgtttg ttctttcttt
    66721 acccattttt ttcaccaact ttctgaatac accagcggat caattcttcc atccgctcgg
    66781 tttgttttgt caaatgcaga tagcccatga gcgcttcgaa ccctgttgcg acccgatacg
    66841 tcgtaacatc agcatttttt gcgctcgtat ggcttttagc atttcttcct ctgcgataat
    66901 aaagttcttc ttcttctgtc aaaagatgtt cttccagcat ttgctgaatc aaaaaggctt
    66961 gtgcattcgc agaaacataa ttcgttgccg cacgatgcag cttattgggt tttgtttctc
    67021 cttgatcaat caggtggtca cgaacataga tttcgtaaat cgcatctcca acataagcca
    67081 aggctaaacc gttcaattgt gtgtaatctc tcatgcttct cttctccatc gggttccttg
    67141 cggtgtatct tctaataaga tccctttttc tttcaacaaa tcacgaattt cgtcgcttcg
    67201 gacaaaatca cgattgcttc ttgcttgatt tcgttcttcg atcaattgtt caatctcttc
    67261 atctaataac tcttctgctg taaataaaat accgaagatc gaaagccatt gcgagaataa
    67321 agcttctcct tgtgccaaga cagcggcaga aactttcggc tggtctagat aagtgttcag
    67381 ccacttagca agctcataga ccactgtgat cccatttgct gcattaaaat catcgtccat
    67441 ttcttcgatg aatcgctgtt ctaaattttc taacaaagcg attttatccg catcatctgc
    67501 caaattctct gaggcagttt cttggcggaa tttcaaattg tcaaacgtat tcttcagtcg
    67561 ttgtaaattg gtggctgctt ctttcatcgt cgtttcactg tagcggatcg gacgacggta
    67621 ttgtgtggtc gccatgaaga aacgcaagac ttgtggatca acgtttttga tcatttcatg
    67681 tacagtgatg aaattcccta gagatttact cattttttca tcgtcttcgc caatcgttac
    67741 atagccattg tgcatccagt aattagcgaa ttttttccct gttttcgctt cactttgtgc
    67801 gatttcattt tcatgatgag gaaattctaa atcttgcccg ccaccatgga tatcgatcgt
    67861 ttctcctaaa tgttttgttg ccataacgga acattcaata tgccaaccgg gacgtccttt
    67921 gccccatggt gaatcccaag aaatctcgcc aggttttgct tgtttccata aagcgaaatc
    67981 taatgggtct tctttttgct gctgttcttc ccctgtacgc tgacttgctc cgacttccag
    68041 ttcatcgatg gattggtcac ttaatttccc ataattttca aatttacggg tacggtaata
    68101 cacatcacct gaagattcat aagcatagcc tttttcaacc aacacttgaa taaatgctaa
    68161 aatatctggc atatgatcca tgactcttgg atgcagtgta gcaggttcga cattcaacgc
    68221 tttcgtatct tcttcaaatg ctcggatgaa acgatcagca acttctggtg ctgtaatacc
    68281 taattcgttt gctgtacgga tgattttatc gtctacatcc gtgaaattcg atacgaaatc
    68341 gactttatag cctcgatatt caaaatagcg tcgaattgta tcgaaagcaa tggtgctacg
    68401 agcatttccg atatggatat aattatacac agtcggtccg cagacataca taccgacatg
    68461 tcccttttgt atagggatga attcttcttt ttttctggtc aatgtattgt agatttttat
    68521 cattctgatc tcctcacttt ttctcctttg attcgaacga cttttgctgg tactcctacc
    68581 gctgtagcgt cgtctggaac atctttcaac acaacggcac ctgcaccgat tttggcgttt
    68641 tttccgatcg ttaccggtcc taatatctgc gcattcgcag agagcatggc tccttgttta
    68701 acagttgggt gtcttttacc cgtttctttt cctgtgccgc ctaatgttac gccatggaat
    68761 aaaatcacat cgtcctcgat ttctgcggtt tcgccaatga cgattcccat tccatggtcg
    68821 atgaacacgc cagttccaat cgttgctcct ggatggatct caacaccagt taggaaacgc
    68881 cagaattgag cattgatctt cgccaataaa aagagccggt gctgatataa aaaatgagag
    68941 aaacgatgcc aaaacaaggc atgaaaacca gggtatgtca aaacgatctc agctgtcgaa
    69001 cgtgcagccg gatcgtttct ctttgctgca tcaatcgctc gggtaaacca actcatgact
    69061 ttccactcct ttcgtaagaa ttttatgtag gaaatcatct tcttataaag aaaagaagcg
    69121 ccttttaaat aagtttcctt atcaaaagac gctttccgcg tggttccact tttcttcata
    69181 atcaatgatt atctctgaca gctaacgcct gttatacgtt cttggctact ttgtttccta
    69241 taaaacagtt tttcctgttt tctgtgtttc gccaagacca ctcccagagg catttcggca
    69301 accattcatt gataccttgc accacccggt atctctcttg taatgatcag ctgcttactt
    69361 ttttctgttc atcgtgttta gttcagtact tgatttaaat gtgctaatga tttttcacga
    69421 ccaagcaatt cgatcgtttc aggcaattct ggaccatgca tttgtcctga tacagctaca
    69481 cggattggca tgaaaagatt ttttcctttt acgccagttt ctttttgaac agctttgatg
    69541 gcagctttga cagttggagc atctactact tccatttgtt ctagctgtgc tttgaatgcg
    69601 tggagaacag taggaactgt ttcaccagca agtacttctt ttgctgcttc attcaataca
    69661 ggatgttcat tgaaaaatag cgtagacaga tcaacgattt ctgcagcata gctcatttga
    69721 ggttgataca ggctaacgat cttcttcacc cattcgattg tcttttcatc tgggttttct
    69781 gctacacgtc catcagcgat tagataaggc agacacatgt cagtaaatgc atctagatcc
    69841 attgctttga tgtaatggtt gtttacccat tgcagttttt tcgcatcgaa agctgcgggt
    69901 gatttactta ggcgttttgg atcgaacatt ttgatcaatt cttggtgttc gaagatttcg
    69961 tcttcgccca caggtgacca gcccaataat gcaataaagt tgaacattgc atctggtaga
    70021 tagcctaatt cgcgatattg ttcgataaat tgcaagattg attcgtcacg tttgcttagt
    70081 tttttacctg tttcactgtt gatgatcaat gtcatatgtc cgaaggttgg tggtgtccag
    70141 ccaaatgctt catagatcat cagttgtttt ggtgtattgg caatatggtc atctccacgt
    70201 aaaacgtgag tgattttcat caaatgatca tcgaccgcaa cagcaaaatt ataagttggc
    70261 ataccatcgc gtttttggat gacaaagtcg ccaccgatat tatcggattc gaacgaaata
    70321 gcgcctttca ccatatctgt aaatgcgtat tctgtattgc gaggcacacg gaaacgtaca
    70381 acagattcta gaccttgtgc ttctttttct gcttgttctt caggtgtcaa gttcgcacat
    70441 gttcctgcgt aatgaggcat ttctcctctt gcgcgttgtg cttcccgttc tgcttctaat
    70501 tcttcttctg tgcaatagca tttgtatgct cgattgctag caagcagctg atcaatcagc
    70561 ggttgataga tttctttacg ttcagattga cggtaagggc cgtattctcc aggattttca
    70621 ggagattcat cccaattcat tcccaaccaa gcaaggtttt ccaactggct tttttcgcca
    70681 tcttcgatat tacgtttttg gtcagtatcc tcaatacgaa taataaagtc tccatcattg
    70741 tggcgggcaa acaaataatt gaataatgca gttcttgcat ttccaatatg caggtgccca
    70801 gttggacttg gtgcatagcg tacgcgtact ttcgtcattt tcttcctctt ctttcaaact
    70861 agactttgac taacagcaaa aattccgtca gttacggctt ctcaaatatc atttatttaa
    70921 agccactcag cacaaatttt accttttcta aggtaaatag taaagccaac tggttgaatt
    70981 tccttaccag ttggctgaat ttctttttta ttttgattgt ttagtctttt tctctgtctc
    71041 ttttttattg tcgattcctc gtcctgcatg tgcaggttta gcaaagatca tgcgtccagc
    71101 agctgtttga agggcacttg ttacaacgac ttcgatacgt tcattcatgt aatgctgtcc
    71161 atcttctacg acaaccatcg tgccgtcatc aaggtaggct actccttgtt ggcgttctgt
    71221 cccggctttt actactagaa cattcatcgt ttcaccaggg atgacgactg gttttacggc
    71281 atttgccaac gcattgatat taagaacagg tacattttgg aattcagaga ctttattcaa
    71341 gttatagtca ttggttacaa tgacaccatc taaaagctta gccaatttga tcaatttgct
    71401 gtctacttca ctgatatctt caaagtctcc atcgtacatt tcgacagata taccctcttc
    71461 tttttgcaag gcatttagga tatctaatcc gcgacgacca cgcacacgtt tcaaactatc
    71521 ccctgagtcc gcgatgtatt gtagttcgta aagaacaaaa ttagggatca tcaaggttcc
    71581 ttctaagaat ccagtctttg taatatcata aatccgaccg tcaatgatca cgcttgtatc
    71641 caagatttta tatttatgga aattttctcc tgattttcgt tctaacagtt gactctcaac
    71701 ttgactagct gtttcttgct cgattttttt gcttcgtgaa ccaaaaactt tcttccattc
    71761 ttcgattcgt gtcgttccca ttctcaatcc cagatagcct aagatgatca tcagtaaaat
    71821 cggcaataca ctattgacga atggaatttc catattgtaa agaggggtcg agatcacaac
    71881 acctaaagtc aatccgatga tcgcaccgat cgcaccgaag agaagataag tcaagctgac
    71941 ctcacttagt ttttgttcta cttgtttgat aatagctgag atatgtttgg ccaacagcaa
    72001 agataataaa aagaaaataa gtgcgcctaa caggctgttg gtaaatgtat tattcagcca
    72061 tccgtttgac tgttgaccga ttgcctgcca agctgagggt aaaaatgaaa tacccaagct
    72121 tgcgccgaca atgatcatca gcaaagtaat gacacgtttt tgcatcgttt ttcctccgtt
    72181 tcgacaatca tttattagtt agcggaacac acgcttcaac gtttcagcca aagttgctac
    72241 tccaactatc tcgattcctt ttggcgcttc ccagttacct aagttgtttt taggtaggta
    72301 tacttttgtg aagccgagtt tttggacttc tttgactcgt tgttcaatat gactgacacg
    72361 tctgatttct ccagtcagtc caatttcacc gatgaaacat tccgttggct gtgttccttt
    72421 ttctttatag cttgaagcaa tactgacagc gatagctaaa tcaatcgctg gttcatttaa
    72481 ttttacccca cctgcagctt ttaagtaagc atcttgattc tgaagaagca acccagctct
    72541 tttttccagc actgccatga tcagagatac ccgattgaaa tcaagacctg ttgttgttcg
    72601 tttggcattt ccgaacatag taggtgtgac taatgcttgg atctctacca aaattggacg
    72661 tgtcccttcc attgccacaa cgatagcaga gccagttgca ccgtctaggc gttcttctaa
    72721 gaaaatctgt gaaggattag cgacttcttc caatccatgc tcatgcattt caaaaatccc
    72781 aatctcattc gttgagccaa atcggttttt tactgctcgc aaaatccgaa aactatgatg
    72841 ttgttcacct tcaaaatata acaccgtatc caccatatgt tctaacattc ttgggccggc
    72901 gatcgagcct tctttggtaa catgaccgac gataaaaatg gctatcccat ttgttttagc
    72961 ggttttgagt agttctgcag tggtttctct tacttggctg acacttcctg ccacacttgt
    73021 gatgtctggc tgcgtcatcg tttggatgga atcaatgata acataatcag gggagatatg
    73081 ttcgatggca cgactgattt cgttcatatc tgtttcagcg tatagataaa attctgtgtt
    73141 gatacttccg aggcgttccg cgcgtaattt tatctgctct gcgctttctt cgccggatac
    73201 atataagact tttccgccta tggctgctaa ttgctgagaa acttgtaaca gcaaagtgga
    73261 tttcccgata cctggatcgc caccaatcaa gaccatagac cctggcacca cacctccgcc
    73321 taacacacgg ttcagttctt ctaattttgt tttgatccga ggttcttttt tagggacgac
    73381 gtctgcgatt tttgttggtt ttgctttttc tcctgtcaaa cttgtccgag ttctgcggtc
    73441 cgttgtatct tgttcgattt cttcgaccat cgtattccat tttccgcaat ttgggcagcg
    73501 tcccaagaac ttaggcgaca catacccgca attttggcaa acaaattgta cttttgattt
    73561 ttttgccatt gtaccgcctc cttttatcct aatcatgaga cattaaatca agcttaagta
    73621 tctttaacgt tttatttact ggaagaacca aatccgcctt gacgttgagc agtcgtttga
    73681 tcttgatctg cttttaaaaa cggcaaaaag atcccttggc cgatacgctc gccttttttg
    73741 atcactacat ccttgaaacc aaagttggtg aattggaaca tgatatggcc ttcatttgcc
    73801 tcattattgt aataatcact gtcaatcaca cctactccgt ttgtcaacac taaaaaccgc
    73861 ttcaacggat tgcttgaacg gttagcaagc tgcaaaaatt catcttctcc catgtaagct
    73921 ttgattccag taggcacgag ggttggtttc aattgttttt cattttctga tacatctttt
    73981 ttcaatccat ctgcgactgt ttccaacccc tttttccagc ctgctttcca gatacttgga
    74041 atcacgacct cttctgctgc ttcaaaatca tagccagcag catgatgtgt agcgcgctgc
    74101 ggtagattga tattttgatc tttatattta gaaataactt caaatcctct ttttctcacc
    74161 ggttttcctc cctaaataaa ctactcctat tctaacatat ccgaggctgt aaaagacttt
    74221 ctttacaaat tcttcaagaa attctgctat cttaaagtaa accattaatt cgttcttttt
    74281 ccaaacgact gcaagttgta caaaaaaact attttttaca tgactttact cgtcaaaaca
    74341 agtagaatag aacgaaatta atgagtggat atttgattga ggtgtcacat gcgtaaagaa
    74401 attaaaaatg caaaacgaat tattgtcaaa gtaggaacaa gtacattgat ttatcccaat
    74461 ggaaatatca atcttgcggc aatcgatcag ttagcttttg tcctttctga tcttagaaat
    74521 cggggaaagg aagtgatctt agtctcatca ggagctgtag gcgttggtat gcataaatta
    74581 catttgtcag aacgtccgac tttgattcct gaacagcaag ctgcggcggc tgttggtcaa
    74641 gccgaactga tgaatatcta taatcaaaga ttcagtgtat ataatcaaca gacggcacag
    74701 atcctcgtga caagagacgt ggtagattat cctgaaagtc gtaaaaatgt gaggaataca
    74761 ttggaacagc ttttgattat ggacacgatc cctatcgtga acgaaaacga tactgtagca
    74821 gtggatgaat tagatcatct gacaaaattt ggcgataatg atcagctgtc agccatcatg
    74881 gcaaaacttg tcgcggcaga ccttttgatc gtcctttctg atatcgacgg gttttattca
    74941 gataatccga ctacaaatcc cgaggctcag atgtatcgct atatcgataa aatcgatgaa
    75001 aagattctgg cacaagcagg tggtgctggt agcacatttg gaacaggcgg tatgcagagt
    75061 aaattaaaag ccgcttctag gatatttgaa gcaaacagcg caatgatttt agcaaatgga
    75121 aaaaatccgg caattatttt tgatattctt gcaggaaaag aagtaggtac tttatttaag
    75181 gaggacttga aatgactgac ttgatgcaat taggacaaca ggcaaaagat agcgcgcaac
    75241 aactagcact tatgcctaca aaccgcaaaa atgagctact tgttcaaatg gcacaaacca
    75301 tcaaaaagaa tcaacaagcg atcattgaag caaatcataa agacttagaa aaagcagtcg
    75361 aaaacaatat cagtgaaacg atgcaagacc gcttgcagct gacacctgag cgaatcaatg
    75421 ccatggctac agagatcgaa aaaattgctt cgttagacga tcctattgga aaagtagatg
    75481 agatgtggac gaacaccgac ggattgagaa tcggcaaaaa gcgcgtgcca ctaggcgtga
    75541 tcggcatcat ttacgaatct cgtccaaatg tcacgacaga tgcagctagt ctagcattca
    75601 aatcagggaa tgccgttatc cttcgcggtg gcaaagaagc attcttctcg aatcaattat
    75661 tagtccaatt attgcagcaa gtactggtca gtgctggcga atctccttat gccatccagt
    75721 ttgtcgatga tacttctcat gaaactgcag gacagttgat gcgattgaca gaatacttag
    75781 atgtgctgat tcctcgaggc ggagcaaaat taatccaacg agtcaaagaa caggcaacgg
    75841 tacctatcat tgaaacaggt acaggaaata atcacgtata tatcgataaa gaagcacagt
    75901 tatctatggc agtgaacatc atcgtcaatg caaaagcttc ccgtccatct gtctgtaacg
    75961 cggcagaaac attgctgatc cattctgaga tcgcaccttt tttcttgcca gctattgaaa
    76021 aagaactggt agaacacggg gtctctttac gtgcggatgc tcgtgcgtta gaatatctag
    76081 agacggctgc tttagcagaa gacacagatt gggatactga atatctagat tatatccttg
    76141 ctgtcaaagt ggtcgattct ttggatgaag caattgcaca tatcaatcgg cataatacta
    76201 aacattcaga aacgatcgtg acagatagtt atgcggctag tcaacgtttc ttaaatgaag
    76261 tggacgcggc ggctgtctat gtcaatgcct ccactcgttt tacagacgga tcggtatttg
    76321 gttttggtgc agagattggt atctctactc aaaagttgca tgcccgtggt ccaatggggt
    76381 taaatgaatt aacttccaca aaatatatca tttatggcga tggacaaatc cgcgaataat
    76441 gtttcgtgtg aaacattatt cccgcctttt gccttttttc tgtaaaggtt ctatccaact
    76501 agaaaggtgt caatatgttt gaaattttaa tgattttttt tatttacctt atttctctga
    76561 atatcgctgc ttttctggga gtcggtattt tatccctttt ctttcaattc aaaaaacgaa
    76621 gcatagggag tcaacgggaa aaatggtcgc agtattttga caaaatcggg caaaaagggc
    76681 tggttacacg cttgcacatt agttacatgg ttgcattatg cttattagcg acaatcaatt
    76741 actattcttt tttcgatcat tcaatcgctt atacgattac gctactgatt gctgggattt
    76801 ttcacttatc ttataaatat cagctgaata aaaaccactt gaatcggact ttccgctaaa
    76861 aaatatccgt acgataagta gagtgccttg aagatcggca aaaaactgcc ggacttttta
    76921 gaggctgtga caaagatttt gtcacagcct ctttttccat ataaacggcg ttcgcctacc
    76981 agctgcctgg taaatctgtt tcctcttcgt taagaagcga aaatccgtca aatgtttcgc
    77041 catcataata acgaagcagc tcatccatgg acaagttcat cgttttttct ttttcttctt
    77101 ccgctgattc agccagtagc tgttcccgat acacctgata cataccagct attttttgct
    77161 gcatcgcttt tctagtttca ccttccgcat tgattattgg caattctttg atatagccac
    77221 gataaatcaa ccgatcatct gaaaattcaa tgggtaattc aacgagtgtc aacccgactt
    77281 cctgaaaata ttcttccagc atctattatc cccccattct ttttcttaaa tgaattttag
    77341 cttacctact gaaaattttc cagtttcatt attttgagaa aaaaagggaa tgtgacaaaa
    77401 atcgtgtcac atcccctttt tccgaataaa tggtgttctt ctgccaactc ctcaatcata
    77461 agtcacaata ttcaacaaac atgagaaact gttttttgaa attgttcctt gtgattcaga
    77521 gttaaacgac agtctcacaa cctcttggta aacggcgttc aatcagctga ccctcggtat
    77581 tagctcaaaa aacggtaaaa tatgagaagc tatttttccg ttttgtttct ctaatactta
    77641 ggataaaacg ctgattttac aacctctgtt aaacggtgtt caatcagctg tccttcggta
    77701 ttagctcaaa aaacggcaaa atatgaggaa ctatttttcc gtttgtttct ctaatactca
    77761 ggacaaaacg ctgattttac aacctcctga taaacggtgt tcaaaagctt gcatctgcgg
    77821 taataagccc aaccaaacga aaaatatgag aagctatttt tgtttggctg ttcttatgac
    77881 ttgatgcagg acagcttttt cacaacctct gatttcttat tcttcttcat ttgtagcaaa
    77941 ataattacgg tgataaatga tacaacatac actgataaga acaatggcac ctgcaaaata
    78001 aaacgcatag ctttcaccaa tatgttcacc aatcacacct gcaataaatg gtgctaaagc
    78061 tccaccgaaa aagcggacaa aactatagct ggacgaagca acgtttcgtt gcagacctgg
    78121 tatttccata gcaatcgtcg tcaacagtgt attgataatt ccttggaaaa atcctgctaa
    78181 cacaatgctg atcggtacaa ggactggcat agaagttcca gctcctaata acagcaaaca
    78241 aataatgaat aagacaaatg ctgctaaaat tgtccgataa gtcgtaaact tccgctcaag
    78301 agccggtgca acgaaaatcg aagcaatagc cagaagcaca ccccagccaa aaaatacaaa
    78361 accgacttct aattcagaat agccaatcaa taaaaatggc gcatacgcaa gtaaagtaaa
    78421 gaatccgaaa ttatataaca atgcgattag tccaactgaa cgaagtttat gattgcttaa
    78481 cgctttgaca ccttcccaaa ggcctacttt tctctttggt ttctcagttt caggtaaaag
    78541 taccgctagg gctataaaac cgcaaaacat caaaaatgct accccaaaaa atggataacg
    78601 ccatgaacca ctgcccaaga ccccaccgac tagagggcca acagccattc cgcagccaag
    78661 tgctgcttca tacatcatga ttgctttttc tgtgttacca actaaaatac tgacgatcgt
    78721 tgctaaagca gtagagacaa ataaagcatt cccgacaccc cagccggcac gtaacccaat
    78781 cagcattccg atattcccag ataatccgcc aagaccagcg aatacaacga tgataaacaa
    78841 tcctgtcatc aatgtttttt tcaaaccgat ccgactagat aagaaacctg taaatagcat
    78901 caccacacca gtgactaaca tgtaactagt aaataacagg gtcgtttcag ctggcgtagc
    78961 gtttaactgt gcagcaatcg tttttaagat tgggtctact agacccactc ccataaaagc
    79021 gatcatacag gtagctgcta caactagcgc tgaacttttc ccctttgttt cttcatttgt
    79081 ttgttcttgt atatctattt gattctccaa tatttccatc cctttctctc tattagcatc
    79141 atacatgatt tattttacat gtcaatatgc acatgtaaaa cgtggaaact ttactgtgat
    79201 ataataaaga aaataagacg agaggtagga tttttatgaa tactttagcc tatatattat
    79261 tatgcgtgct tttatccaaa ccacgttctg ggtatgaatt gaagcagctg atcacaattt
    79321 tttgggaagc ccatcacagt cagatctata caacgcttgc caagttagac cagcagggtt
    79381 atgtgaccgt tttggacaaa gacgagcact ctcaaaaaaa gatctaccac ttgactgatg
    79441 aaggacgtgc tcttgtagag gaatggatca aagaggaaac tcccgctcct acgcaaaaag
    79501 atgaatttct agcaaaaatc tatgcttttt cgacgctcga taaaacaaca gctactggac
    79561 tgctattcac tagagaacaa cagctgaaca aaatcatgca aaaaaatcaa aaaaaattga
    79621 atgacctctc gctagacaag aaacaagaat ttggacgtta tgttgtgatc cagcgcagaa
    79681 ttatgctttg tcagcaggaa ctccaatggt gtcagcaagt aagagaacaa atgcagcagt
    79741 tttttgagta agggataaac agaacctttc tagaaatatc tattgaagag caaattatct
    79801 tcaataaaag agcaatacag ttggaaaaga aaaagcgatc cgaacgacag gccaaaacct
    79861 atcgttcgga tcactatttt tctagaactg cattcaagag actatgacaa aaagcatgcc
    79921 aaggcctttt ttcaaataac agtgttccat cattcattac tttgaattgc ttttagcaca
    79981 cttcttgaaa gcgggccaac gatgatcaac tgcaacggta aagcggcaat cacattcatt
    80041 ttccaagcat tcatataagc agagaataat tgatcaggta ttccttgttc catgatcaca
    80101 ccgaataaag acatacatgt caccattcct aaaaccatca agcatgaaat agttaagatc
    80161 atttggacct tgctttctgg atttactggt agtttaaagg caattttttt cgccagcaca
    80221 ccgatgatga agacatccaa aatgaaagcc accacgaatc caggcactag accaatcaac
    80281 aaacttgata aatgaagatc ttgatgcagc cataaattat acgcgctcat ccccaagacc
    80341 atcaaaaaac acatcattgt tgtaaaaatt attccttctt ttttatttgt aggcaatctg
    80401 taccactcct ttaaatttgt cacgaaaatc atcgtagcac atttaaaaat ttctcgtaag
    80461 tacttttttt attttctgcc cttttatttc ataaacttca tcagccgtac gctcgacaaa
    80521 gtaagaatca tgagaagtaa acaaaatcgt tcccggatat atttgcatta gcttctctaa
    80581 agcttcgatc gttgccatat caataaaatt agtcggttca tctaacagca acacattact
    80641 tggcttagta aaaagcaaag caatcgtcag acgggtcgct tctcccccac ttaatgtaca
    80701 taacggtttc gtcaaagttt cctgagcaaa ccctaagtga ttcagcaaac tacggacaag
    80761 cgattctgaa aactctgttt gtctcatgac aaaacgaatg atggattctt cagatgtcat
    80821 ttgataaccc ttttgctgat atacttgaaa gcttactttc ggagagagaa ggattccttc
    80881 tccttgtttg cggatatgtt ctaataaggt tgtcttacct gaaccatttt caccgacaat
    80941 cgcgattttt ttacctaaag aaaactgaaa atcaccattt accagtaatg ttctcccact
    81001 tctttccaat tggacatttt gtcccatgat gggatagcgg ctgtggagtt caagagattt
    81061 tggtactgga aaacggattt gtttcatctg ctgcggcttg gttgtttctc ctattttttg
    81121 gagtcttctc tctaatgttt tcgcattctt ttggatggct ttttgtacac tgtctttttg
    81181 tttagaggaa gacaaccgat ccagtctgat ttgttgcttt ttctttttac tggacacttt
    81241 ttccaacttt tccgcttgtt ttttcttttc ttggatcgat ttttccaatc gttttttctc
    81301 tttcatgatc gactctgctt ctcgtagctg agtctttttc tccaattcct tttgagtgag
    81361 ataggcacta taattccccg aaaactctcg gatttctccg tcttttactt cccagatttt
    81421 cgatgctagc tcatctagaa aatagcgatc atgactaaca aaaaccagcg taccataata
    81481 ataacgaagc tcttcaatca gtcgatcaat actttttcta tctagatggg ttgttggctc
    81541 gtctagaagc atcccttgtt cataagaaga aagaagacgt atcaactcga tctttcgttc
    81601 ttcccctccg ctccatttcc gctctgaagt ttcttccagt cttaactgga aatgactggc
    81661 taattccaaa tttaggtcct ttgcttcagc gagataggtt aattgaggca ggtagttgaa
    81721 ggtgatctct gtttggattt tcccatgatc gggaaaaagt tcaccggcta ttagtttgag
    81781 caaagtcgat ttaccgacac cattttctcc tatgatccct atacgatctt gctgatagac
    81841 acgaagagaa tcaatagata gttctagctg gttgccaaag ctgacttgta gatttgttat
    81901 atttactgct aaattttcca tatgttttac actcctattt catgtaaaac aacaattatc
    81961 gatactaaaa aagagcagaa aaatctgttt gcaaaaaaac tgcatcacat cttttcctac
    82021 tctgaacgaa ataactatga ctaaatcacc aaatctgtca tagctttcac ctattctact
    82081 gtcgttcgaa aaaatggaca tactccatcc atgaaattgt tgtttataca tgtcttttga
    82141 atttatttag ttgttattca aaagttcgaa acgtaatttc atcgatgcag tcatttttcc
    82201 gacctccttt tttattaggt taccacacac gattcaaaaa aagcaatagc tactgaatag
    82261 taactgaaaa ccttttattc gaacatagtg atcttttctg gtgctaaacg aacagactcg
    82321 taaccttctt ctaccgcttt tcctattgat aaaataataa ctggaacata acggtcttta
    82381 tccaaaccaa atgcctctgc caactgatct gcttcgaatc caccaattgg atttgtttca
    82441 tagccatgat cacgcgcaac taacatgaat tgcatagccg ctaagctaga atcgactttg
    82501 actacatcgt tcatttcttc tcttgaaaaa ctcttgtaat aaggaatgat cgcagctaat
    82561 tgttgatctc tgacttcttt tggcatcttc cctgattcgt aagcttggtt gtagatttct
    82621 tcgccatatt cgtaacattg catatcgcca aaaatcatga ccattgcaga agaagtatca
    82681 ttttgtctcg tattgaaacg gatcaaagga cgcaagattt cttttgcttc ctcgctttca
    82741 gcgaccacaa agcgccatgg tttcatattg acagaagaag gtgcagtcgt cgcttctttg
    82801 atcatttcca gcatttcttc gtgtgggatt ttgtatgttt catcatatac gcgaacggat
    82861 cttctaccag tcataattgt tgaaaaatca tttttttgtt ccattattat taacctcttt
    82921 cgtttctgtt gttatattgc aaagttgggt attcaattta tctaaaagtg ttagaaattg
    82981 tttcatttct acatcgctga aagccgggga tagcacggaa cctgtatctt tatggtccat
    83041 ttcacaatgc ttgattttct tctgggcttt ttctgttagc gctacataca cttcccggtt
    83101 gttctgagga tttctctgac gcgaaacata gccatttgct tccaatacct tcagatgacg
    83161 agtaactgct ccttgatcaa tctgcaactt ttcttgcaaa ctgctttgta gcaatggatt
    83221 ttcttctttc agtctcatca tgatctcgta tctagtaaga cttataccga tattttcttc
    83281 aaagatctgg acgatttttt gatcggctaa tttgatttga tataaaaggt gactaatctc
    83341 ttctaaagac ataatttcct cctttctaat aattgactcg tcaacgattg acttgtcaat
    83401 aatagaataa aaaaagaaaa aagtcaaaga atcagctgtg taataaaaaa aacgctctca
    83461 atagaaaagt atagagaaaa gaaatttttt gtagaatgaa cggaaaaaat gataaagaaa
    83521 gcacaacgct aaaaccaaga ttattgattc ttatcaaact atagaagata gctcttctgc
    83581 agtagataat tttacaccgc caaaaatttc cgaaatcgcc ttttgcaaga atcccgtcga
    83641 atattagaaa ttggatcagt atgcttaaac agtaataaaa aagttatgac aagatgttgt
    83701 cacaaccttt tttgagtaaa cggtgttcaa aaacttgcat ctgcggtaat aagttcaacc
    83761 aaacaaaaaa catgaaaatc tgtttttgtt tggctgttct tactacttga tgcagggcag
    83821 ctttttcact acctcttttt aataaccata aaatcctatt ccttcatatc tccagcccat
    83881 cggtgttagc caatctcttt ccttagcact caaggtatag tgatgggtac cagttttttc
    83941 atttggatta aatagtcgat aaattggctt ggaaccacca gaataaaaac ttagaccttc
    84001 ataacgccaa ccgatttttg ttaaagagtt gatctcagat tgtgccattg tgtaatgatg
    84061 gtctccactg taaggattgt ataaacggta gacaggttgt ccgctgtttg gtgcttgcca
    84121 agcaatccct tcatattccc agcctacagt tggcagataa tttttttctc cggcattcaa
    84181 tgtatataaa tgttctcctg tatgacggtt atacagacga tacatcggag aagttgaagt
    84241 tggtgctgta tcatactgtg tcagattata ggtttcgatt acattgttca atgtagaacc
    84301 ataattaggc gcagtggcat aacgacctgt tagccaagcc gtagcatctt tgtaagagtt
    84361 cgtattgctt ttccatgcac cggaatagta gtaaacgcct ggctgaaaag aagtcgtctt
    84421 caataccgtt acgttatctt gcaatgattc tttgtacgaa ggatattttc taaaagcggc
    84481 attcaccgta atccattgcc cattcacata ttccgaagta ggcatcgtaa cagattggcc
    84541 attatagctt cctttaatcc caaatagatt gtaattaggg gcagaagcca aagtactgtt
    84601 cccccagcca ctttcaacga tggcttgagc aatcatgact gatgcatata agtcattggc
    84661 acttgccaaa ctttgtgcag ttgaggcaat actatcaatg aacgcttgtt gagaattagc
    84721 agatgagcga gcataaaaag catagccagt atagttttcg aattcagaca aatctgcttg
    84781 atgggtatgt gtcaatgttt gcccatctgt caattggttc gtgatttctt ctgcattctc
    84841 tggattgttc tgagcttctg ctgatgtact gtcttcggtt tgtgtttgtt ctgttgtttc
    84901 agttgttggt tcttcggttg aaattgtatt ttctgagaca gtagctgact gcaaagtact
    84961 ttctgtatcg ttttcaattc ctgtttctga agaactcgat gtctgagttg cgacagtttc
    85021 tgtcgattct tcagctagca ctgttgtgtt ggcaactgct agatttccta aaagaataac
    85081 gctaaataat aaattctttg ctttcatctt ttttctcctt tgaattatga aacttttcct
    85141 aaataacagt gtaactaaaa aagtaaaagc aagtcaatgt ccatatttaa ataacatttg
    85201 tttcttttta ataaatttgc tttttctgca taaaaagacg taaatgaaga atattcttct
    85261 ccattcacgc cttaaattga tggtcgtttg aataactatt taacaagtaa ttctctctgg
    85321 atattatccg ttatggatta tacttcctgt gtcgtcggac ggataatcat gttgctgaca
    85381 gacatccggt ctggcgtttc tatcgcaaat gctacagcag aagctatatc ttcagatgtt
    85441 aatccccatt ctttttgcgc ttcatgaagt tcaagagcag cctttttgtc gctgatggtt
    85501 tgatataatt cagtttgaac agctcctgga gagatgatcg tagatttgat gttattttgc
    85561 cgttgctctt gacgtaatcc ttccatgatt gcacggacag caaattttgt tccgcaataa
    85621 acggcggaat caggataaac aacatgtccc gccacagaat cagttgaaat gatatgccca
    85681 gatttttgtt tttccatgat tggaagtacg gcggaaattc catttaacac acccatgatg
    85741 ttgatatcaa gcatattttg ccattcatca cggtgacctt caactaatgg agcggttggc
    85801 atgattcctg cattattgta caatacatcg attcgaccga acttttccat cgctaaatcg
    85861 ataactgctt ggacttgtgc aaaatctctt acatctgctg tttgaatata tagctcagct
    85921 tctggtaaag attcttttat tgcttttagg cgatcttctc ggcgtgcagc tataactagt
    85981 ttagcccctt tttctgctaa tagcttcgtt gttgcttcac cgattccgct tgaagcgccc
    86041 atgatgacaa tcactttttc tgataaatca ttcattctat tctcctcctg ttttgaaaaa
    86101 tctcttgctt atactcacta tctcttattt catcttactg ttcaaataat ccgttcgaca
    86161 ggtttgacga ttttggcagg gattcctgca acgatggtat tgtctgggac atctttcgta
    86221 acagttgcat tcgctgcaac aatggcattc tcgccaatcg ttacgcctgg cagaatagtt
    86281 gctcctgctc cgatccaagc atttttcttg atgtggattg gctttactga caagcctctt
    86341 cgttcttttg gatcggttag atggttcacc gtgatgaggt tgacacgagg accaatcaat
    86401 actgaatctt ctaaacagat gccacctaag tcaacgaaca tcacttgacg attgataaag
    86461 acatttttcc ctatactaat atgtttgccg aaatctgtat aaaaaggcag cagaacagtc
    86521 accgtatcat ctactttgtc actaatgata ttttctagcc gtttgcggat atctgctggt
    86581 tcatggtacc cagtattcag cgctgctaaa ggctcttcgt tttccgcttg gatctgatgg
    86641 atcacttcaa agagcggatc cgttactcga atctctttat tgacgatttg tttttcgatg
    86701 aggcttgtca ttttgctccc tccttttatc cttactttat aacggacggc ttatgatgtc
    86761 taatacttat aaaacatact taactattcc ttttaactat acttagtggt atgctttttt
    86821 aaaaacagga gggaaaaaat ggatattcgt atactgacgt attttttagc agtagctaga
    86881 gaaaaaaata tcagccgagc agcaaaatct ctgcatatca cgcaacctac tctctcaaaa
    86941 caactgaaag atttagaaga agaacttggt gtgacacttt tcactcgagg ctcccgagag
    87001 atacagttga cggattctgg tcgatatctt tattcaaaag gaaaagaaat cttgtcgttg
    87061 gtagaaaaaa cggcgaacaa tttaacaaat gacgcaatca tctctggaga aatctacatt
    87121 ggcggaggcg aaactaaagc aatctctttc atttctgata gccttcattc gttgatcaag
    87181 gcgcatcctg atatccagtt tcatttatat agcgggaatg cagatgatat catagacaaa
    87241 ctggatagcg gattacttga ttttggactc gtaatcgaac cgacaaacaa acaaaaatac
    87301 cagtcatttc gactgccagc ccaagatcgt tggggacttt tgatacatcg gaatcatcct
    87361 ttagcaaagc aaacagtcat ccatccgcag gaactgaaaa ctgttccttt gatcatttcc
    87421 cggcaaacgt cagtggacag tcaactagct gaatggctag gtttcagcat agatcagtta
    87481 tcgatcgtcg gaacatataa cttattgtac aatgcttctt tgatggtcga taacgggact
    87541 tttggtgcat tagctctaga tgggatcatc aatacttatg ggacggaaaa agtattcatc
    87601 ccactcgatc cgccattaca agcttcactg aatctcattt ggaaaaaaga ccagcctctt
    87661 tctcctgctg ctcgtaaatt tttagatgtc ctaacggaga aatacagtta agtagagttt
    87721 ttttccttcg ctttcagctt tttaacaacg aataagttaa gcaaaagatc caatgattaa
    87781 ataacataag tttcttaatt tgttccttcc ttttatttct gataattcca gtaaattact
    87841 ataattataa aaaaagaatt gacaaaacat aactgtctat ataaaattga ttacgttaac
    87901 aataattcgt ttcatgtgac tagatcatac taggcatgaa aaatctctga ggaacatggt
    87961 ttccctagga ggtttttcgt gtctattttt gtttggccgc aatcaactgg tctagcaaac
    88021 gtgaaaacca aatcttcaaa aagggtgcgc gcatgaaaat caaaaagatc tttaatcaaa
    88081 atgcagtatt ggtagatgac ggtggacagg aaaaagtagc tattggaaaa gggattggat
    88141 ttgacagaaa aagaaatgat ttgatttttg atcgtgatgt cgaacggata tttgtcatgg
    88201 aaccagaagg tcaaatcaag ttgcaaaatt tacttaatca gattgatgaa cgctttttat
    88261 ttgcagcaga aacgatcatt gatcatgcgg aaactgtttt gatggaaaag ttgaatgaac
    88321 atgtattgat cgctttgacc gaccacattg ctttttctgc ggagaacatt aataacggta
    88381 tcgtcatccg caacaaactt ttaagagaaa tcgaagtgct ttacagtgat gaattcagta
    88441 ttgctcaatg ggcagtagag tatctgacaa aagagcttgg gattccatat acttatgacg
    88501 aagcaggata tatcgcaatc catattcaca gcggacgaag cggtcggaac aataaccatc
    88561 gcagtatccg tgaagtgacg attgtatctg acatcatcca tttagtggaa tcagaattgg
    88621 aaacagatat ccattcagaa ccattttcac tgaattattc aagactggtg aatcatttac
    88681 gactgcttct acaacgaacc catgcgcaac aatatgctgt tttagacacg gaaatcgtag
    88741 aaatggtcaa acgaaaatac ccagaaagct ataagatttc taaaaaaatc cgtgtgttgc
    88801 tgaccaaaga ataccagctc gcgatcacga aagaagaact gggttacttg gccatccata
    88861 tcgagcgttt aagaagcgca atcgtacaaa caaatgttaa caatcatgag gaggaaaaaa
    88921 attgaaagca tatctacaac gaatgggacg ttcccttcaa cttccagttg cggtcttacc
    88981 tgctgctgct ttactagtag ggatcggaaa ctggtgggca tcttatagta acgacattgt
    89041 cgctcatttt ttacaagctg gcggtaacgc agttttaggt caattacctt tgctgtttgc
    89101 cgttgggtta gcactaggga tgtcagtgga caaatcaggt gctgctgcct tggcaggttt
    89161 ggtcgcattt gaagttccag taaatgtttt aaaaactgat tcagtagcta ctttattgaa
    89221 tatcaaacca gaatcagttg atccatcttt tgctcagatc agtaacgtat ttattggtat
    89281 tattgccgga ttgattgcgg cagctcttta taatcgtttc cacgaagcaa aattaccgat
    89341 ggctttatct ttctttagcg gcaagcgtct agtgccaatc ttggctgcct ttgtcatgtt
    89401 gctgatcagt gcagtgctac tgctcgtatg gcctccggtt tactctgctt tagtttcttt
    89461 tgctaaattc attttgagtt taggctgggg tggtgcaggt ctttatggct tcttcaaccg
    89521 tttactgatc cctacaggat tgcatcaagc aatgaactcc gtgttctggt ttgacgtagc
    89581 aggaatcaat gatattggta aatttttggc ttctgaagga acaaaaggcg taacaggaat
    89641 gtatcaagct ggatttttcc caatcatgat gttcgggctt ccagcaggag catatgctat
    89701 ttacagaaat gcacgtccag aaaacaaagc aaaaacagct tccttgatgt tagcagcagc
    89761 ttttgcttca ttctttactg gtgtaacaga accacttgaa ttctcattta tgttcgttgc
    89821 ttggccatta tatgtcttgc atgcaatttt cactgggatt tctttagcag tgagtgcatt
    89881 cttccattgg acagcaggat ttgcctttag tgccggattt gtcgattact tcctatcttt
    89941 gaaaaatccg attgcgaatc agccattgat gttgatcgtc caaggattag taacagcagt
    90001 gatttactac tttggcttta actttgctat caaaaaattc catctgatga ctcctggccg
    90061 cgaggaagca gatctttcag atgacgatac tgcaacgact aattcagaca ataaatatgc
    90121 ggcacaagca agcaaaatct acgctgcatt aggcggagcc gacaatgtaa cttcgatcga
    90181 taactgtact acacgccttc gtttgcaagt caaagataca ggcctgatcg atcaaaataa
    90241 aatcaaagcc actggcgtac ctggtatgaa gatcatcgac ggaaaaaatg cgcaagtcat
    90301 cgtaggtaca gaagtacaat tcgttgcaga tgagatggca aaactacatg gtggtgctgc
    90361 aacacgacct gcacaaacaa acaccgtggt taaaacagaa acatttgccg gtggaacgat
    90421 cgaacaagat atttacgcta tcgcaaatgg gaaactgatt ccaatcactg aagtttcaga
    90481 tgatgtattc gcggaaaaaa tgatgggtga cggctatgct gtattaccag aaaatggaga
    90541 aatcttctct ccaatcgctg gtacgatcac aaacattttc ccaacgaaac atgctgtcgg
    90601 aatccaaaca gatgctggta tcgaagtctt gcttcatatg ggcatcaaca ctgttgactt
    90661 aaaaggcgaa ccattcactt tatatgtaaa agaaggtcaa aaagtcgcaa gaggtcaatt
    90721 gattgcttta gttgatcttg ccgctattca atctgcaggc aaaaacacgg atatggtcgt
    90781 tgtattcaca aatggcgaca aagtccaaag cttagaaatc gaacccgcac gtgatgtaaa
    90841 agcaaatgat aaaatcggct ctgtttccaa caaagcctga gccatcgtct tccccagact
    90901 tttttatcga taaacaaaca ggagctgaga caaaaatctt gtctcagctc ctttttccga
    90961 ataaaaacgg cgttctcctg ccaactccgc ggtaataagt ccagccaaac gtaacatatg
    91021 aagagctatt ttttatttga ctcttcttat tacttgatgc agaacagctt ttttacaacc
    91081 tctgataaac ggtgttcaaa aaccagttta tcggtatgaa gtcaaattta tgcaaaaatg
    91141 tggaaagcca ttttcacaaa atttttcttc atactcaaaa ctaatcggct ttttcacaac
    91201 ctctttatac attattcctg atccaatatt tcttttaatg ctgcttcaag agaagttaat
    91261 ggttttccca atactttttc taaatcatca gaggaaatag ctaactgatc ctttttaata
    91321 tcatgttgga tcgctaaaaa catgtcagct gcttcttgag ggaatccggc ttcttttaga
    91381 ttttcgacaa acgctgcatc acttgcttca ataatttcta actttttacc tgtcgcacgc
    91441 tctaatgcct tggctaattc ttcatagtca gttagattgc cggataattc taagatttct
    91501 ggagagtcac tttctactag tacttttgct gcagcttctg catattcacg tttcaatgcc
    91561 caacctgttt ttccatttcc tgcagcataa acgaattgac cagtttttaa agcctgccca
    91621 atgataggta attcattctc tacataccaa ttattccgta aaaatgtatg ggaaatacct
    91681 gaatccttaa tcattttttc agtgaattgg tgatctggcg ctaatacact gatcgagtga
    91741 tcggcatctg caaaacttgt ataagcgata taagataccc cagctgcttg tgctgccttc
    91801 actacattct tatgttcggc ttgacgattt cctggaacgc cagagacaaa aagcaatcga
    91861 tctattcctt tcaacgcttc tttcattgag tctaaatcat cataatcacc aatacgtata
    91921 ttaaatccag cttctttcag tgcttctcct ttttcttcac tacgtactag tacatagatt
    91981 tcattttgtg gaaccatctt ttttaagaat tccagcgcat aaccaccaaa acctccagtt
    92041 gctcctgtta ctaaataatg catatttgcc actccctatt ctttttattt gttaagattt
    92101 acagctgtac atttataaat tacaccttta tcataaagag tgtggtaaga taagtcaagc
    92161 aaaaaaaatg aaaggatgac aactgatgaa gtattctctg caatttagtg atgcaatcca
    92221 tgtacttgcc tatattgaaa tgtttcaaga tacccgatca ctttctagtg agatgattgc
    92281 cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc atgagtcagc tcaaaaaatc
    92341 cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc cttgccaaaa gtccagatca
    92401 gatttcttta ctagatgtct atcgcagcat cgaaggtaat acacagctta tccaagtcga
    92461 tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc caagaagctt tagaagaaag
    92521 ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct aagatcacac ttgatagtct
    92581 gatacataaa atagccgttt tggaaaaaga aaaaagacca gaaaacacag gcctcgtaga
    92641 gagattttta taattctctc tactgtgcct gcatttttct gatcggaatc gtctacataa
    92701 attcttttat tctccggggg acaaaagcct tgtcatgccc ctttttcctc tctaatgctc
    92761 aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg ttcaagtagc tgaccctcgg
    92821 cattagttct gaaaaatgca aaatatggaa agctatttcc catttttcct ctctaatgct
    92881 caggtcaaag cgctactttc acgacctcta tattatcatg gtttattgac taccggtatc
    92941 cagatttctc ccatatattt cccgttggta actcccattt cgactacagc atttggaccc
    93001 ccaacatagg cgtaatcttc tacttctctt aaaacatgcc caaaggccgt attcgtcaaa
    93061 tcatttctta attcttcagg cgattctgct aaagcgatta caacaagata cgttcctttt
    93121 gggaatggga tgattcgggt agtgtttgga acatcctgac tcgtttgaac accgacatag
    93181 tacatcattt tcccgttata gggttcgttg actgtaaaga aataatgatt ttcagcagct
    93241 tgtttcaatg catctattgt tccattaccg ataacttttt gctcaaatgc ttgtttctct
    93301 gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt ccacaccaat acccgtcacc
    93361 gtaaaatctg gtttttcttc gatcctatac tttgccattt ctcccaccct ttctattata
    93421 ttaagttcat cttacataaa attaaaggga aatgacacga ttacgctctt ttttctaggg
    93481 atatttttat tttttaacta tttttttgct ttcactgcaa tccaaatctc actgtaaaca
    93541 ttactgaaat cctctcccca ttttgtaaaa gagatctcgg gagcttcgac taactcataa
    93601 tctgaagaag gaagccattc tgcatagatt ttcccccaag tatcttgtaa agtttgggga
    93661 aatggccctt tattaggaaa aatggcccaa gtgtgttctt ctatagcaag catttctaaa
    93721 tcagcgtacg gattttcttt tgtcgtagca aagccaatca tgtgcatcaa actgcccttt
    93781 tcttccaagc gggctccatc aaatccataa gaaacgttga ttacttgatt tggatataaa
    93841 tctcctaact tatgcatctc ttccctttga gtctccgtga tcgtctgcgc taacttttgt
    93901 atttcttgat tgactccttc aaatttgaca ggaacttttt tcgccacacc tgccacataa
    93961 aactgttctt tcttttcgat acgaaattcc atcgattttc ctcctctgac atcaataaaa
    94021 aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc tgatttctga aggcagatat
    94081 cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg tttcatatcc atatctaaac
    94141 gccgtttctg tcactcttga tccatctagg agatcgcgat tagccaaagc caatctacgg
    94201 tttttgatat agtccattag cgacatccct gcaataaacg taaagatgcg ttttaattga
    94261 tattcagaga ttcctgtatt ttcggctatt attttatagg aaagtccttc tgtcaaatgt
    94321 tcttcgatgt aatcgatcaa ttggttcaga tctttaagca tatttatctt cctccttgct
    94381 tgccttttta tcatattatc aaagaaagtc aattacttga tgaatcagga accaatttag
    94441 tcagatgtag aaaatgttgt atggatctaa agaaaattct caagcagcgt ttcgtaacgg
    94501 ataattggta ttatctgcct atctatgttt tacctttaga aaaataaatt ttggggaaga
    94561 cacattctaa gtaaacaaag cggtaaaaat atcttttatt cccttagtta atccgcttac
    94621 tacctactgt acaaagcaaa ttgttgttca aac
//
LOCUS       DAFKHN010000002        87285 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFKHN010000002 DAFKHN010000000
VERSION     DAFKHN010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 87285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.002"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(108..956)
                     /locus_tag="LY912_000087"
     CDS             complement(108..956)
                     /locus_tag="LY912_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBM6953814.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(980..1666)
                     /locus_tag="LY912_000088"
     CDS             complement(980..1666)
                     /locus_tag="LY912_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6953815.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(1659..2693)
                     /locus_tag="LY912_000089"
     CDS             complement(1659..2693)
                     /locus_tag="LY912_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6953816.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(2756..3012)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3088..3426)
                     /locus_tag="LY912_000090"
     CDS             complement(3088..3426)
                     /locus_tag="LY912_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBM6953817.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(3428..3784)
                     /locus_tag="LY912_000091"
     CDS             complement(3428..3784)
                     /locus_tag="LY912_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBM6953818.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(3790..4977)
                     /locus_tag="LY912_000092"
     CDS             complement(3790..4977)
                     /locus_tag="LY912_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBM6953819.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(5168..6013)
                     /locus_tag="LY912_000093"
     CDS             complement(5168..6013)
                     /locus_tag="LY912_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBM6953820.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            6247..7212
                     /locus_tag="LY912_000094"
     CDS             6247..7212
                     /locus_tag="LY912_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBM6953821.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            7712..8755
                     /locus_tag="LY912_000095"
     CDS             7712..8755
                     /locus_tag="LY912_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBM6953822.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLFYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(8817..9281)
                     /locus_tag="LY912_000096"
     CDS             complement(8817..9281)
                     /locus_tag="LY912_000096"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBM6953823.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            9527..10474
                     /locus_tag="LY912_000097"
     CDS             9527..10474
                     /locus_tag="LY912_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBM6953824.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(10685..12757)
                     /locus_tag="LY912_000098"
     CDS             complement(10685..12757)
                     /locus_tag="LY912_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBM6953825.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLNLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERIPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(12690..13067)
                     /locus_tag="LY912_000099"
     CDS             complement(12690..13067)
                     /locus_tag="LY912_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBM6953826.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(13196..13774)
                     /locus_tag="LY912_000100"
     CDS             complement(13196..13774)
                     /locus_tag="LY912_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6953827.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINDFIATLP"
     gene            13906..15198
                     /locus_tag="LY912_000101"
     CDS             13906..15198
                     /locus_tag="LY912_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBM6953828.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMSFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            complement(15258..16376)
                     /locus_tag="LY912_000102"
     CDS             complement(15258..16376)
                     /locus_tag="LY912_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBM6953829.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVNPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16390..17811)
                     /gene="arcD"
                     /locus_tag="LY912_000103"
     CDS             complement(16390..17811)
                     /gene="arcD"
                     /locus_tag="LY912_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBM6953830.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(18057..19178)
                     /gene="mnmA"
                     /locus_tag="LY912_000104"
     CDS             complement(18057..19178)
                     /gene="mnmA"
                     /locus_tag="LY912_000104"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBM6953831.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGDMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            19582..20181
                     /locus_tag="LY912_000105"
     CDS             19582..20181
                     /locus_tag="LY912_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBM6953832.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELITQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(20319..21605)
                     /gene="efmA"
                     /locus_tag="LY912_000106"
     CDS             complement(20319..21605)
                     /gene="efmA"
                     /locus_tag="LY912_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBM6953833.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(21876..22220)
                     /locus_tag="LY912_000107"
     CDS             complement(21876..22220)
                     /locus_tag="LY912_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBM6953834.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(22357..23502)
                     /locus_tag="LY912_000108"
     CDS             complement(22357..23502)
                     /locus_tag="LY912_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBM6953835.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(23681..24655)
                     /locus_tag="LY912_000109"
     CDS             complement(23681..24655)
                     /locus_tag="LY912_000109"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBM6953836.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(24735..25610)
                     /locus_tag="LY912_000110"
     CDS             complement(24735..25610)
                     /locus_tag="LY912_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBM6953837.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            25740..27647
                     /locus_tag="LY912_000111"
     CDS             25740..27647
                     /locus_tag="LY912_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBM6953838.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNEQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIQYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(28065..31355)
                     /locus_tag="LY912_000112"
     CDS             complement(28065..31355)
                     /locus_tag="LY912_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBM6953839.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGPDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKDHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERLTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNQATGEVLENAKDLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     ASYETKEILHTVDYRKPNYSTVYVTPEGSDTGNGSRQNPLSLTQALRYAYAGQTIVLA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWVLR
                     GFDVTNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVVIK
                     NSVAYRNGWVPGVEGEGNGNGFKMGDSSLSGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDFHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTVSKDWIESLNTHSQEGQQPVTRYANGSIHVHGLMQIKPEN
                     RQTEKGRVDGLPLSVGATFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVV
                     YVMKQRKK"
     gene            complement(31626..32171)
                     /locus_tag="LY912_000113"
     CDS             complement(31626..32171)
                     /locus_tag="LY912_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBM6953840.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(32183..32875)
                     /locus_tag="LY912_000114"
     CDS             complement(32183..32875)
                     /locus_tag="LY912_000114"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBM6953841.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(32894..33178)
                     /locus_tag="LY912_000115"
     CDS             complement(32894..33178)
                     /locus_tag="LY912_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953842.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(33191..33754)
                     /locus_tag="LY912_000116"
     CDS             complement(33191..33754)
                     /locus_tag="LY912_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBM6953843.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            33982..34644
                     /locus_tag="LY912_000117"
     CDS             33982..34644
                     /locus_tag="LY912_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBM6953844.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            34768..35964
                     /locus_tag="LY912_000118"
     CDS             34768..35964
                     /locus_tag="LY912_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBM6953845.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(36065..37441)
                     /locus_tag="LY912_000119"
     CDS             complement(36065..37441)
                     /locus_tag="LY912_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6953846.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVIILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(37478..38344)
                     /locus_tag="LY912_000120"
     CDS             complement(37478..38344)
                     /locus_tag="LY912_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBM6953847.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(38433..39458)
                     /locus_tag="LY912_000121"
     CDS             complement(38433..39458)
                     /locus_tag="LY912_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBM6953848.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(39476..40150)
                     /locus_tag="LY912_000122"
     CDS             complement(39476..40150)
                     /locus_tag="LY912_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6953849.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(40334..41227)
                     /locus_tag="LY912_000123"
     CDS             complement(40334..41227)
                     /locus_tag="LY912_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBM6953850.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(41301..42998)
                     /locus_tag="LY912_000124"
     CDS             complement(41301..42998)
                     /locus_tag="LY912_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBM6953851.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(42991..44304)
                     /locus_tag="LY912_000125"
     CDS             complement(42991..44304)
                     /locus_tag="LY912_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBM6953852.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(44304..47822)
                     /locus_tag="LY912_000126"
     CDS             complement(44304..47822)
                     /locus_tag="LY912_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBM6953853.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(48115..48573)
                     /locus_tag="LY912_000127"
     CDS             complement(48115..48573)
                     /locus_tag="LY912_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBM6953854.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(48870..49388)
                     /locus_tag="LY912_000128"
     CDS             complement(48870..49388)
                     /locus_tag="LY912_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBM6953855.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(49390..50007)
                     /locus_tag="LY912_000129"
     CDS             complement(49390..50007)
                     /locus_tag="LY912_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBM6953856.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(50004..50858)
                     /locus_tag="LY912_000130"
     CDS             complement(50004..50858)
                     /locus_tag="LY912_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6953857.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(50855..51766)
                     /locus_tag="LY912_000131"
     CDS             complement(50855..51766)
                     /locus_tag="LY912_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6953858.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(51807..53141)
                     /locus_tag="LY912_000132"
     CDS             complement(51807..53141)
                     /locus_tag="LY912_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6953859.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            53349..54179
                     /locus_tag="LY912_000133"
     CDS             53349..54179
                     /locus_tag="LY912_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBM6953860.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(54423..54741)
                     /locus_tag="LY912_000134"
                     /pseudo
     CDS             complement(54423..54741)
                     /locus_tag="LY912_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(54863..55057)
                     /locus_tag="LY912_000135"
     CDS             complement(54863..55057)
                     /locus_tag="LY912_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953861.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(55562..55747)
                     /locus_tag="LY912_000136"
     CDS             complement(55562..55747)
                     /locus_tag="LY912_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953862.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(56597..56938)
                     /locus_tag="LY912_000137"
     CDS             complement(56597..56938)
                     /locus_tag="LY912_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBM6953863.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(56938..57168)
                     /locus_tag="LY912_000138"
     CDS             complement(56938..57168)
                     /locus_tag="LY912_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBM6953864.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            57455..57793
                     /locus_tag="LY912_000139"
     CDS             57455..57793
                     /locus_tag="LY912_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953865.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(57998..58237)
                     /locus_tag="LY912_000140"
     CDS             complement(57998..58237)
                     /locus_tag="LY912_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBM6953866.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(58213..58560)
                     /locus_tag="LY912_000141"
     CDS             complement(58213..58560)
                     /locus_tag="LY912_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBM6953867.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(59292..59873)
                     /locus_tag="LY912_000142"
     CDS             complement(59292..59873)
                     /locus_tag="LY912_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6953868.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(60056..60682)
                     /locus_tag="LY912_000143"
     CDS             complement(60056..60682)
                     /locus_tag="LY912_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBM6953869.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(60704..62035)
                     /locus_tag="LY912_000144"
     CDS             complement(60704..62035)
                     /locus_tag="LY912_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBM6953870.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(62190..62591)
                     /locus_tag="LY912_000145"
     CDS             complement(62190..62591)
                     /locus_tag="LY912_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBM6953871.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(62677..62883)
                     /locus_tag="LY912_000146"
     CDS             complement(62677..62883)
                     /locus_tag="LY912_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953872.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(62978..64480)
                     /locus_tag="LY912_000147"
     CDS             complement(62978..64480)
                     /locus_tag="LY912_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBM6953873.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(64498..64953)
                     /gene="argR"
                     /locus_tag="LY912_000148"
     CDS             complement(64498..64953)
                     /gene="argR"
                     /locus_tag="LY912_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBM6953874.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(65051..65668)
                     /locus_tag="LY912_000149"
     CDS             complement(65051..65668)
                     /locus_tag="LY912_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBM6953875.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            65889..67262
                     /locus_tag="LY912_000150"
     CDS             65889..67262
                     /locus_tag="LY912_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6953876.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            67337..68449
                     /locus_tag="LY912_000151"
     CDS             67337..68449
                     /locus_tag="LY912_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBM6953877.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(68521..70158)
                     /locus_tag="LY912_000152"
     CDS             complement(68521..70158)
                     /locus_tag="LY912_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBM6953878.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(70326..70934)
                     /locus_tag="LY912_000153"
     CDS             complement(70326..70934)
                     /locus_tag="LY912_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBM6953879.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(71318..72469)
                     /gene="queG"
                     /locus_tag="LY912_000154"
     CDS             complement(71318..72469)
                     /gene="queG"
                     /locus_tag="LY912_000154"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBM6953880.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(72488..73240)
                     /locus_tag="LY912_000155"
     CDS             complement(72488..73240)
                     /locus_tag="LY912_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953881.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(73381..74331)
                     /locus_tag="LY912_000156"
     CDS             complement(73381..74331)
                     /locus_tag="LY912_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBM6953882.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(74332..75171)
                     /locus_tag="LY912_000157"
     CDS             complement(74332..75171)
                     /locus_tag="LY912_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBM6953883.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(75168..75914)
                     /locus_tag="LY912_000158"
     CDS             complement(75168..75914)
                     /locus_tag="LY912_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBM6953884.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            76152..77522
                     /locus_tag="LY912_000159"
     CDS             76152..77522
                     /locus_tag="LY912_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6953885.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(77577..78473)
                     /locus_tag="LY912_000160"
     CDS             complement(77577..78473)
                     /locus_tag="LY912_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBM6953886.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(78587..78757)
                     /locus_tag="LY912_000161"
     CDS             complement(78587..78757)
                     /locus_tag="LY912_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953887.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(78754..79431)
                     /locus_tag="LY912_000162"
     CDS             complement(78754..79431)
                     /locus_tag="LY912_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBM6953888.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(79522..80427)
                     /locus_tag="LY912_000163"
     CDS             complement(79522..80427)
                     /locus_tag="LY912_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBM6953889.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            80602..82056
                     /locus_tag="LY912_000164"
     CDS             80602..82056
                     /locus_tag="LY912_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6953890.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            82072..83103
                     /locus_tag="LY912_000165"
     CDS             82072..83103
                     /locus_tag="LY912_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBM6953891.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            83110..84297
                     /locus_tag="LY912_000166"
     CDS             83110..84297
                     /locus_tag="LY912_000166"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBM6953892.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            84453..85835
                     /locus_tag="LY912_000167"
     CDS             84453..85835
                     /locus_tag="LY912_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBM6953893.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            85962..86192
                     /locus_tag="LY912_000168"
     CDS             85962..86192
                     /locus_tag="LY912_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953894.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(86392..87060)
                     /locus_tag="LY912_000169"
     CDS             complement(86392..87060)
                     /locus_tag="LY912_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBM6953895.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        24898 a        18322 c        15597 g        28468 t
ORIGIN      
        1 tcttttattt attattaaac aattttgatt tctaaattag aataggtata aaaaagatga
       61 gaaataagcc attacagact tatttctcat cttttttgtt ccatacctta ttttgcatca
      121 gcctttactg gtttaacaga gccgccccat ttgtctgtga tccattcttg gacttctttg
      181 cggtgaagca cttcaatcag ttttttgatt ttgtcactgt cttcatcacc tttacgagtc
      241 gcaataatat tcacgtaagg agagttgtcc ttttcaagca atacggcatc ttctaatgga
      301 ttcaaccctg cgccgtaagc gaagtttgcg ttgattgcaa ctaggtcacc ttcatcattt
      361 tggtacgtag aagctaaaag tgatgggtcg atcgtatggt tgaacttcaa gttcttaggg
      421 ttttcttcaa tatcatcgaa tgttgctgtt tccagatcta ctccatcttt gactttgact
      481 aagccagcat cttgtagaat tgtgatgatg cgtccccagt ctgattcaga atttgaagta
      541 atgattgttg caccatcttt taattcggaa acatctttga cttttttaga gtacaagccc
      601 attggttcga tgtggacagc accggcattg acaaagtcat atcctttttc tttgatttct
      661 ttgttcaaat aaggaatatg ctggaagtaa ttggcatcaa tgtcgccttc ttccaaagat
      721 tggttcggta atacatagtc atcgaatttg acgatttcaa gatcgattcc ttcatctttc
      781 aataatggtt tcacatgttc caaaatctct gcgtgcggtg tcggtgaagc gccgactttc
      841 aatgtcgtgt cgtctgcttt atttgctgaa tctttgctgt cgctgttgtt accgcatgct
      901 gctaatccta cagtcagcaa aagcgctgct gcaaatccaa aaattttctt tttcatatcc
      961 tacatccccc tatatcctat tatcttttgt ctgttttctt agttaagaaa tcaccgattc
     1021 cttgaacgat aaatacgatt agtaaaataa ttaaagtcgc aacgaatgtc actgtcagat
     1081 taccacgctg gtagccttcc tgccaagcaa gacctccaag tccacctgcg ccgatcgcgc
     1141 cggccatcgc agtaaatccg atcatcgaga tcgttgtaac tgttaatcca gaaatcaatg
     1201 cgggaatact ttctggtatc aagaccttcc agatgatttc ccagtaactt gctcccattg
     1261 catctgctgc ttccagtaca ccagggctga cttcacgaaa agcaatctct actagacggg
     1321 cataaaatgg tgctgcggat aaaacaagag ctggaatggc tgcttgcgca cctagcatag
     1381 tgcctacgat tgctttagta aatggaatga tcaaaaccat caggatcata aatggcgttg
     1441 accggaaaat attactgatg atcgatacga ttccataaat gattcgagca tacggtttgt
     1501 ttttgcgtcc aatagagtaa aggatcaatc ccaaaactaa tccgatgatc gtcactaaga
     1561 ccattgagat taatgtcata tatagtgtat caaggatagc ctgattcatc gtttccgggt
     1621 tgatttgttt aaaatctaga tatgtttctg aaaagctttt atccacgatg gatcacctca
     1681 attcctactc cttgttcttt gatgaacact tctgcttgat ctaattcttt ggtttcacca
     1741 gtcatcaaga cagtcaatga accaaaggaa ccttctttca cttgtttgat ctttccatac
     1801 acaacgttga catcgatgtt atagcgtcga atcgcttggg aaatgactgg ctcgttggca
     1861 tttctttcgc taaaggtcaa agttgccaaa cggccgcttg gattttcttt gatgagttca
     1921 gctaatagtt ctgtcgaatc agcttctggt tcgatgtctt gttgtacaaa gcgtttggtt
     1981 acttcttttt tcggttgtct gaagacagtc aatacgtctc cttcttctac gactttcccc
     2041 aactccatca cagcgacttt gttgcagatt ttgcggatca cattcatttc atgtgtgatc
     2101 aagacgatgg tcaaattcaa tttcttattg atcgctaaca ataagtctaa tacttcttct
     2161 gttgtttgcg ggtccaatgc gctagtagcc tcatcacaaa gcaggatctc aggatcattt
     2221 gccaatgctc gtgcgatacc gacgcgttgt ttctgtccgc cggaaagttg tgaaggatat
     2281 gcttgtccgc gtccttctaa cccgactaaa cgcaacagtt cttctgcccg ttctttacgt
     2341 ttgctctttg gtacgccagc taattccagc ggcagctgga tattttcaag tacagttctt
     2401 gaccataaca ggttgaaatg ctggaagatc ataccgattt tctttcggaa tgtacgtaat
     2461 tctttgtttt ttaattttgt aatatcttga tcgtttacga tcacttcgcc gctcgtggga
     2521 agctcaagtc cattcaggag acggactaat gtactttttc ctgcgccaga atagccgacg
     2581 attccataaa tatccccttt ttcaacgttt agtgaaacgt cattgacggc ttggatgttt
     2641 ccgtttttcc cattgaatgt ctttttgaca ttcgttagtt ggattaatga catgccattc
     2701 acatctttct cttatgattt ttcaaacaaa aaagccttcg ccctcttgcc ttaagcaaaa
     2761 ggacgaaagc ttgaacttcc gtgttaccac cttgatttac cgttacttcg caataacagc
     2821 ctcttccagt acttggactt agcttctttc cgtatactgt cgcgctgtaa cgggcactcc
     2881 cgtagtaagt ttgcttacgc tcgcttactc tgctctaaga ccatcttcca tctcattttc
     2941 gttacccatt ttcagcaaac agggctctct tcaaacgtcc gtgacatgta ctcttctttt
     3001 caaagctttc tcgtttcata taggattgct tatgattata gcaactggaa gaatcagtgt
     3061 caactttttt caagtgattt tctgatttta taattcgtca aattcttttg gatcaacatc
     3121 tttgaaactt aagatccacg cattcatttc atctgaatca ttcaagatat tgatatcttc
     3181 accgatttta tcattaacag aagaaactgt acccgttagc gggctggcaa attcattgac
     3241 cgctttttcc gcttcaactt cgatcagagg ttcatctttt tttagcgatt gtcctgcttt
     3301 tggcagattg gcaaacgtga tgtctccaag ttcttcttgc gcttcatttg tcaaaccaac
     3361 acagtattct tttccattaa ataagatcca aaggttgtcc tttttcttca aatgcttgcc
     3421 tgccatttta tatcagttct ccttcataaa ttttttcatt gaatccaatt gcaacaagct
     3481 ggtcctctcg taagatcagt ggccgcttga tcagcatacc atctgtcgat aagacttggc
     3541 tcgcttttga agccgtaaac tcgcctactt gatctttcag tccaagttcc cgatatttca
     3601 tcccgcttgt gttgaacagg cgacggattg gtacttgact cgtttctagc caagtctcaa
     3661 tcgttgaggc cttcggtact tctttgatca tatcaacagt ttgataacta acgccatgct
     3721 ggtctaacca cgctttggct tttttgcatg ttgaacattt cgggtaccag taaaaggtgt
     3781 acaattttct tacctccttg aagatcttgc aggtgcttca ttttggtatc tcatcgataa
     3841 tatcaacccg ataccgatca tgttccctaa aatcgaagat cctccctgac taatgaaagg
     3901 caatgggatc cctgttaaag gaagtaatcc gatatttgct ccaatattct caaagacatg
     3961 gaacagcagc atcatgatca aaccgcttgc gatataggcg taaaattcat tattcgtatc
     4021 gaaacacacc cgaatcatac gatagattaa aataaaatac aagaaaatga cgaatgcacc
     4081 accgataaag ccgaagtttt caccgataac ggtaaaaatc atatcggact cacgaacagg
     4141 cacataaata ttgcttacgt tgaatccttt accaaacaag ccaccggtac caattgccaa
     4201 aagtccttgg gccggctgat aactcattcc tgacgtatca tggaaagggt ccagccatga
     4261 atcaatacgt gcaaactgat aagatttgaa gccaactttg taaagcaagt ctcttccgcc
     4321 ttcagtcgta accaagaaga tcgttcctgc tccaacgact actgccaaga ttactacagg
     4381 tgcgatgatg cgccaagaga ttccagacat caagaaaatc ccgccaaaga tcgcaagaaa
     4441 gacaagcatc gttccaaagt catcttgggc catgatcaat gctaaaaccg gtattgtcac
     4501 gatcaagagc ttcccaatca gccaaaagtc cgatttcatc gtccgttctt ttacttgcgt
     4561 attatgttta gttacgatca gtgccatcat caagatgtac gcaatcttca tcaactctgc
     4621 tggctggaaa gtaaacgcac cgaatcgaaa ccagttttta gaccctgttg aagcagctaa
     4681 attctgatca tagaatttga gcaagagtcc cattaccact aaccccaaac cataaaggta
     4741 aggagtcagt ttccagatcc atttggaatt caaatgcatg atgacaacga ttgctgccgc
     4801 tccaactaaa taccagacaa cttgcatccc tacgcctttc aagactgctg gattgttcgg
     4861 atcatggcta agtgctacat ataatgagag cagaccaatc aaacataaca gaaagactgg
     4921 taaaatcacg ccataatcaa tacgattatc gttcgaagct tttaattttt tttccatgtt
     4981 tcatcccttt tcttaaaaac catactgctg attattatag cggtccagtt agataatgga
     5041 aagtctttcc atagacattt gggaaaaatt aactttccgt ttgtgcagtt gcttgagcaa
     5101 atgcagtaca aaagcctact gcttatcttt agtgtatcat agaacttttt ttgatacatg
     5161 caattatcta ccagctgaga ttctcctcgc tgtgagaagt ttctgtgctt tcattgtatc
     5221 gaaggatctc ttcggcaatc tctagcagct gatcagaaac cagattggtt cgttggatga
     5281 aataaaaata tcgatggaaa ttcaacggag tcattggcac attttctgga acagagcgct
     5341 tagacaaaat cgagcgaccg attccttcct tcagcaacgc aacaattaca tcgttacttt
     5401 tcacgatcat cttcttatct tggatattca tctcttcaaa ataacgctgc gtataatgaa
     5461 aaacaccaga gtttgcttct cttacaagcc acaatttgct ttttgggtcc ccagcgatga
     5521 ctagctggtc ttccatcaaa gagtatcttt gtacgccgga agtctctaat ggcttttcga
     5581 taaaaccaaa atcggattca tgtttcgcta cttgttctaa tgattcatga gaattcgcga
     5641 tttcgatctc aaaatgcact ttaggaaacc ttttgatcag atgtttcatc aactgaggca
     5701 aaagatagac agcaaaggtg tgggaagcaa cgatccgaca tacttcttct tcattttgtt
     5761 cattgagcaa tttttgctga gtttcttccc attcttctaa caaaaccagt gtccgttcat
     5821 ataataagtc ggcttgctta gttggaagca tctcttttct tccgttacgt tgaaaaagat
     5881 cgatattcaa ttcccgctcc aactgtttga tttgattcga gactgctggt tgagataaaa
     5941 acagtacttc tgctgctctg gaaaaatttc ttgtttcata tactgctcga aaagtcgtta
     6001 ataacttaaa catggcacca cttccataac tttttatgat aattactata aaaactattt
     6061 gatttaaata tacaaaaaac catctataat agaaatgtac aacaaaacag ttgctgatcc
     6121 aactagtaac ttagatgaag acaatcagct gtctgcttgc tcgtaatcat acattcctat
     6181 tcattttaca atgtattcgt tcatcttggt actaaaatct attaaataaa aaggagaata
     6241 ttatatatga agaacttttt gaaaattatt ccgatcccga tctgcgggtt gatccttggg
     6301 ttagcttccc ttggaaatct gtttaaagac tatcaccatg ttgctttagg caatctaact
     6361 ggcggtatct ctatgattct tatgatattc atttttgtta aattgtttat cttattcgaa
     6421 cacacgaaac aaacgttgca tgatccaatc atcgcctccg tttcaccaac ttttacgatg
     6481 tcactcatgg ttatttgtac ttattttgtt tcatatgaaa gtattgcacc aattgtcaaa
     6541 ttcatttggc tgtgcgctgt tatcttccaa gtgatccttg tcttttattt caattatcac
     6601 catgttatca aagctgatct ttcaattgaa gcaatttatc caagctggtt tatcatttac
     6661 gttggatttg gggtcatcac tgtaactgcc gggaacttct tcccgcttat tggaaaaatt
     6721 ttcttttgga tttcattgat ctgctatgcg ttcttattgc cgatcatcat caaacgtgtc
     6781 tttttcgtaa gaaatatggc tcatccgaca cgtccgctga ttacgatcgt tgcagcacct
     6841 ggttctcttt gcctaacagg ttatcttaaa aactttgctg aacctaattt ttatcttgtc
     6901 gtagcattgt tcgctttatc tcaagtattg tatttcgttg tgctgtctat gcttccacgt
     6961 ttgttcaagc ttcgttttta tccaagctat gcagccttta cattcccgct tgttatctct
     7021 gcaacagcta tatttactac tgttcattac ttcaacagtt taggtatcta tagtagcgta
     7081 ttggatttct taaaagttgc ggaatgtctg tttgcaagtg tagttgtctt ctacgttctt
     7141 gctcattacg tacgtttctt aattaaagaa catagcaaac atggaaaatt tgtttctaaa
     7201 aaaatcgctt aataatcgat tcaataggtt gtgaaaaagc tgttctgcat caagtaataa
     7261 gaacggccaa acaaaaacag ctgttcatgt ttttgtactg gttgggctta ttaccgcaga
     7321 tgcaagcttt tgaacaccgt ttaccaagag gtcgtaaaag aagtggtcag cttcaagaaa
     7381 taagaaggaa tttacgaaaa ttgcttctca aatttttgtg aaatttcggc ttatttccga
     7441 agaagctact tctggaacac cgtttaccaa gaggtcgtga aaaagccgct tagtttcgag
     7501 tattaagaaa aattttgtga aaatggcttt ccacattttt gcataaattt ggcttaatac
     7561 cgagaaactg gcttttgaac accgtttatt cgaaacaaga ggtcgtgaca agacttttgt
     7621 cacgacctct tgttcttttg tcaaaatact ggtttagtgc tactatgttc gagtatgctt
     7681 ttagtattta ttgacgaaag gaaccgatca aatgaaatca ttgtcacatc caataaaatc
     7741 tgtaaaggat tcagcggtcc gcgaaatctt acccggttta ctgctttctt ttgccatcgc
     7801 tgccttcagc aggcttcttg ctatttatct gccacagtta ggtggagcga ctattgctat
     7861 tttattgggt attttattag gaaatacttt ttttaaacag cctgttctag caatcggcac
     7921 aaaatttgct gaaagcaaac tattagaatt ctctgttttt ttactaggtg caactgtcac
     7981 agctcaaacg attgctcaaa ttggtataaa aggaattgtt tttgtgttac tgcaaatgtc
     8041 agtcactatc atcggtgctt acttgattgg taaaaaactg caattcagcg atacttcttc
     8101 tttgatgatg gctggaggaa acgctgtttg tggttcttct gctattgctt cgatcgcccc
     8161 ttccatccat gcgaaagagg aagaaaaagg acagatcatc acactagtca atctactggg
     8221 tactgtgatg atgttgactc tcccttttct tggattacag ttgtttggtg gaaatctcat
     8281 tgaaaaaagt gcacttttgg gtggcacact ccaatctgtt ggtcaagtag tcgctggggc
     8341 aagcttactt gacaattctg ttgtcgaatt cgccatgcta tttaagattc tacgtattat
     8401 gatgctcgtt gttgttgtct atctgtttga aaaattcatg cacaagaaac aaccagctct
     8461 gtttgaaacg ccaactgata cgcagaaaaa acgaaaatta ccacttcctt ggtatgtatt
     8521 agggtttgtg atcttttgtt tggtcaacag cttgttttct ttacctgtag ttattgacca
     8581 atcggcacat tttatcagca gctggtttga gatcactgct ttagcggcaa ttggtctgcg
     8641 tttagacttt gcaaaattca tgaaagaagg tacacgcttc ttattttatg gattagctgt
     8701 cgggcttctc caaacagtga tggctttact atttatttgg ctgatcaaag tttagaatga
     8761 acatgaaaaa acagttgtga ttctcgcatg gaacaatgtc cgaatcacaa ctgtttttaa
     8821 ttttgcagat atccttctaa caacaacaat tggcgtttga tttcaacccc atctattgcg
     8881 tttcccatat atcctgtcag ttttccattt tgcccgatca ctcgatgaca aggaataacg
     8941 attggcaatg gattggttcg atttgcctgc ccaatcgctc gcacagcttt cggactatca
     9001 acagcaacgg ctacttcttt atacgttcgg atttctccat aaggaatggt cgacaaagct
     9061 ttccagacat tttgctgaaa aggcgtacct ctctttatag ataaaggaac atcaaattct
     9121 tttctttttc ccgcaaaata ttcttcaaac tgttcttgtg tgcgcgttaa aatttgctga
     9181 ttcgctgatt cgctttctga aattggctga aaagatacag cagtcaatcc ggattcatct
     9241 gcatctaacc ataaaaagcc gataggtgtg tgtattttca ttttgtttgc ttctagtcaa
     9301 tagactggaa cttcctcctt tttctctatc caaaactact tgccaactaa taaaaattgt
     9361 tcttaaaagt ttgataaacc gaggaaacat ggtaaactaa atacgttagt ttacaaaaag
     9421 aatacctgtt cttttacgta aaatcaaatt ttaaaggtgt tatttaaggt ttattaaatt
     9481 ttgaatgtaa accatatata aacatacgat tgaaaggata gaaacgatga aagtatcaat
     9541 tgttgtccca tgttttaatg aagaaaaaac tgttcctctt ttttttgatg aggttgaaaa
     9601 attcaaaggt gcccatgagt tcgaatattt gtttattgac gacggatcaa aagacggtac
     9661 gttagcagca atcaagaagc tagcctcagc ttatccttat gtccgctttg tctcattttc
     9721 cagaaatttt gggaaagaag cggctctata cgctggattg caagcttcta caggagattt
     9781 agtgaccgtg atggatgttg atctgcaaga tccgcccgaa ttgcttcctg agatgatcaa
     9841 ccggatcact acttctgata tcgattgtgt cggcacccgg cgttcgactc gtgaaggcga
     9901 gcctgcgata cgcagtttct ttgcgaaaaa attctaccag ttgatcaata aaatcagcga
     9961 tacagaaatg gtcgatggcg ctcgtgattt ccgcttgatg actcgtcaaa tggtggatgc
    10021 cgtcctagaa ttaacagaat acaaccgatt ttcaaaagga ttatttagct gggtcgggtt
    10081 taaaacagaa tatatttctt atgaaaaccg cgaacgtgtg gctggcgaaa catcttggtc
    10141 cttctggaaa ttattcaact actcgattga tggtatcgtg aacttctcgg atgcaccgtt
    10201 aacgattgct tcatttatcg gcgctttgtc ttgtgtcggt tctggtattg caattttgtt
    10261 cattattttg cgggcattgt tgtttggtga tcctacatca ggatggcctt ccatggtctc
    10321 gatcttcctg ttcattggtg gaatccaatt gttatgtctt ggaatcatcg ggaaatatat
    10381 cgggaaaatc ttcttagaaa cgaaacagcg tcctgtttat atcataagag aaacagaaaa
    10441 agtgaagcca aatgaattga agcctcacca ataatatacg tcaaatgaag taaacatttt
    10501 tttaaatgaa aaaggactgt gacaaaagtc ttgtcacagt ccttttttcc gaataaatgg
    10561 tgttccagaa gtagcttctt cggaaataag ccgaaatttc acaaaaattt gagaagcaat
    10621 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttcatat
    10681 cttattattt cttcattgcc gcttttagtg ctgctgctaa tgggctttct tctggttctt
    10741 ctgcttgtgc atattttttc agcaagcgtc gttcttcatg tttggtcatt ttcttcttct
    10801 gctctttttt atcaagcatt ttttctgtcg ttccatcgta tttacaacgg aaataagcac
    10861 cgtttttacc ttcgatgatt tccattttcc ggtgacattg cgggcatcga tgattagaga
    10921 cttttggatc ttttcttctg cggtagttgc aatctgaatt ggtgcagaca tagattttgc
    10981 cgtcacgtgt gtttttctcg cgcagattgg ccccacattc tgggcatttc ttttgggtaa
    11041 tcgagaaatc ttgatattct tgtttgcttg atttgatctc attcaccaag cgttttgttt
    11101 ctttttcgat tccattcaag aaggttcctg cttgtttctt tcctgcagca atagcttcaa
    11161 ggtctttttc ccagctttct gtcaaatctg gtgttactaa agagggattt accaatacta
    11221 ataattgctt acctttagga gatacttgca gtccttgagg gatacgttcc atcagttcag
    11281 atttgattag tttctcgata atctctgcac gcgtagctgg ggttcccaga ctgtattttt
    11341 ccatttgacc aagcaagctt gcttctgaca atggtttagg cggtgcagat agttcttttt
    11401 tgatggcgaa atcgggattg attctcattc ctttttccca tttgactgtt tccgtctcag
    11461 tttcagtttc gcctttccat cctgcttgga cgacacgatt ttgccgaaaa atgaatcgtt
    11521 ctttaccaaa ttcaaccgta acttttgttt ggctgacttt atggggttga gcaaacagtc
    11581 ctaaaaaacg agagacaatc atttgataga ttttttgctc ttcattactt aatttttcat
    11641 aacgtgctct gttttcagtt ggcaaaagtg catggtgatc ggtcacttta ctgtcttgga
    11701 atacttttgt ctgttggacg atggctccgt ttttcaaata ctgcttgacc tcaggagcaa
    11761 agtcgctgac tgcttgcaat cgttctttca tcgtactttt catgtcattt gtcagatatt
    11821 tgctgtctgt acgcggataa gtaacgatct tatgggtctc atacaaactt tgtacaagat
    11881 ttaatgtttt ctttgcagaa tagccatagc gttgattggc ttctctttgg atctctgtta
    11941 aatcataagg caatggcgca gattccgttt ttaatttttc ttggacttct gtgacagttc
    12001 ctttgcttgt actgatcaat tgaacaagtt tttgtgcttc ttcttgtgtt tttaaagcaa
    12061 attgattttt ttgaagcatt ttggcttgtt cttttccagc ttgcaacgtg atcgtgaaat
    12121 acgtttgtgg acggaactgc tcgattttct tttcttggtc tctcactaat gctagtgtcg
    12181 gtgtctgcac acggcctgct gataaattat ccgcgtactt cacagttaag gctctggtca
    12241 cattcaatcc taccagccag tccgcttttg cccgggcaag agcagattca tacaatgcat
    12301 catattcttt cgcaggtctt agttgcttga atccagtttt gattgcttta tctgtttgag
    12361 aagagatcca taaccgcttc actggtttat tgaaatgcac atactctaag atccagcgag
    12421 caacaagttc cccttctctt ccggcatctg tcgcaatgac tgcttctgag acatcttttc
    12481 gctgagctag ctgcttgatt gcttttaatt gatgtcctgt tttaggaagt ggtttgattc
    12541 ctagtttttt agggatcatt ggcaacgtgt ccatttgcca gctctgccat tccttattca
    12601 gatcttccgg cattttcaat cctaataaat gaccaagggc ccaagtaacg atcaccttgg
    12661 gtccttcata ataatttttg tgcttttgat tagcaccaag caccttgctt aggtctttcg
    12721 caacgcttgg tttttccgct agaattagtt gtttcataaa attcctttcc gctttctact
    12781 gtgatgggct gatgattttt caacaacgca agtcctttgt attgctgtaa atcatcgtca
    12841 cactcttcac accagcgctc atctccgtca ttccaaaagg cgctgagaaa gttacttttt
    12901 gcattgatat attcataatt ttgatggatt tcgttccatt gtttttcgta cgcttgtcgt
    12961 gcttcttcga aagactcgaa tgtttcttct gcttcaatat cttcttccca gtcttcaaaa
    13021 aaccaccaag gctcattgtc cccgaacatg gtaattactt gatacatact cgtgctcctt
    13081 ctttcagctt ttctagactc atcttagtca cttttcaaga aagttgcaag aattttctct
    13141 tataaaaggg tcatttaatg aacatcttaa aattgttaca aatgaatctg attgtttaag
    13201 gcaaagtagc gataaagtca ttgatcatcc aaaaatagct gtcttctgga tcgattgttg
    13261 gttcttttgt aaagtatcct aaaaaacgta aggaaagata accgtggatc atactacgaa
    13321 gttccctgct tcgatgaact ttttcttctt tcgttaattg aaaagcctca aatatctgca
    13381 aaatgatctg attcgtttca tggattccat ctaataaaac agcttcattg gtatgcggta
    13441 cactgatcag taactcatac actgcttgat ttgaaaaagc aaaggatcga taagtttctg
    13501 catagatctg cagtgcttcc tgaccacttt ttcctacaag agcccgacgc agctggtcat
    13561 taagttcctg cagaagtttc gctgttagcg ctgttttgac atcacgaata tttttgaaat
    13621 ggttatacag cgagggagcc ttgatatcca agcgtttggc taaatgctga aaggttattt
    13681 gctgaacatc catctcttct gctagttctc gaaagcagtc gatgattttc tcttgagaca
    13741 gatttctttt tttcatttcc atgtttcctc tcataaaata aatccttcac tctttcagtt
    13801 taccacgaaa aagaaagaga aaaaagagac tttcattgat aaactacata ttgtagttta
    13861 taataaagat ctgtagatga aaattttcag aaagaaggag tctaattggc tgcaagaata
    13921 aaggaaaaat tatttaggaa aagagaaact tgggaacaaa acttgtttgt cttatggttt
    13981 ggaacattta tggctggtat cggatttagt ttagtcatgc cttttatgtc actttacata
    14041 gatacgttag gtaattatag tacgtcacaa ttgaactttt ggagcggatt gactttttca
    14101 tctactttct tggtgactac gctgatctct ccttggtggg gaaaattagc cgaccaaaaa
    14161 ggaagaaaat tgatgctgtt gcgtgcttca ttaggaatgg caatcgtcat ttctttgatg
    14221 ggttgcgtga ctagtgtgta tcaattagtc gcattgcgtc tgcttcaagg gattttttct
    14281 ggttatatca gtaatgccac tgcccttgtc gcaactggga cgccaaaaga aaaaagtggt
    14341 caagttcttg gaaccttagc aactggttct gttacaggaa cattacttgg accgcttctt
    14401 ggcgggatct ctgcttcagc gtttggctat cgccctacct ttttcattac agggatcatc
    14461 ttatttttcg tcttcttgtt gagtctgttt ttcgtccatg aaaaatttgt cccagtgaaa
    14521 aaagaaaaca tggtttctgc caaacagatt ttcaaagact tgaaatatcc acacgtcgtc
    14581 atcggtatgt tcgtcacaac gatgatcatc caagcatcca acaattccat tagtccaatc
    14641 atcagtctgt acattcgcca attgctgcat ggacatggga atgttacgtt gatcagcgga
    14701 atcatcgctt cgatacctgg gattgccact ttgatagccg ctccaagatt tggtcgctta
    14761 ggtgacaaga tcgggagtga aagaatactt gcgattggtt tgggttttgc gattctggtt
    14821 tatatcccaa tgtcattcgt cacgaatgtt tggcaattag ctgccttacg ttttttgatt
    14881 ggtatctctg atgcttgtct gctccctgct gtccaagcat tgatcacaaa atattcgcct
    14941 catcaagctg ctggacggat cttcagttat aaccaatctt tccaagcaac tggtaacgta
    15001 gtagggccta tgatcggctc cagtgtttcc agtgcatttg gttatcgtgg cgtttttctt
    15061 tcgacttctc ttcttgtttt ggtcaacttc ttgcttgtac gacacaatac acaagaaatc
    15121 catcagcaag aaactgcaga agaaaaagct tcaggagtct ccatatcttc agggcactct
    15181 ccttctcata gacaataagc gtaaatgaaa aacactgctt gaacagttgt cacagactgt
    15241 ccttgcagtg tttttgttta ggcctgtttt ttcaagaact cagataagag gaataatccc
    15301 ttttccaagg tttctttttt acaacagtaa cctagtcggg catgcttcgg taaatcaaag
    15361 gcacttcctg gtactaatag tactcctgtt tcttctaata aattgataca aaatgtctgg
    15421 tcatcttctt cgatggctaa tttaatgaaa gaagtagaga cgtaattggg agcgacaagt
    15481 tcaactttcg gttcattggc tacccattgt tttaaaatca caaggttctc tgtaatgatc
    15541 tttttgtttc gctccaatat tttttcttta ttcttcaatg catgtacagc aagatcatct
    15601 gacaggactc cgccgcaaat catcgtgtag tctcgatact ttcgaaaaac ttctgccaac
    15661 tcaggtccag tagctgtcca gccaatacga atacctggaa tggagtaggt tttggatagg
    15721 gaattggttg ctataccttt ttcatagaca tctacgatcg acaagaattc acctttatcc
    15781 gttaaaggcg catatacttc atctatcaat acatatgcat ctactgtacg agcaatttct
    15841 gcgatttttt ctaaagtttt ccgatctagc aatgtgcctg taggattgtt tgcactattc
    15901 aaacagatga tttttgtttc aggtttgact aaggcttcta gctgttctaa atcaaactgc
    15961 caatcttctt cttccttcaa atgaacaaag tcaacagcgg cacctaaaga tttggggatg
    16021 tcatataatt gctgataagt aggaagcatc gaaacaacat ggtctcctgc ttccactaac
    16081 gcgtatagag ctaaaagatt agcaccagtc gctccattcg tttgtaagat gttttccgga
    16141 ttgacggttt gataaagaga agcgacttct tgtttgaaaa catctgatcc ttcgatccag
    16201 ccatagtcca atggttcgtt tttgcgtttt tcgaaaaatt cacttacgct agtcccatct
    16261 aagccaacga gttcgtctaa tgtcaatgct tcgatcgagc tttgtgcaat atcatatacc
    16321 gctttctttt cccatttatt tagccattct tctacaccga aatttgcgat tttcatgttt
    16381 ctttccccct tatatcttga tccagcctac agcaagcaac ccgattgaaa gcagtgcggc
    16441 cacacaaatc agcccaatca ttactttttc ttttcccgta atttgatgtt tggtttcacg
    16501 acaagcgatc cagtagaagc aaaaaccagg aagataggca atactacata aaaggacata
    16561 agaaaatcct gctaaaatga tgcccatcaa ttcaaaaact acagcaatcc caccgatcac
    16621 tacttgtttt ttgattcctt cttttaaaga aaactggact tgatagatcc cgacaagtag
    16681 ataacaaatc aaaattgccg ctgtacataa agaataggca aattgatagg cataatcagt
    16741 aactaagaaa gtcaataaga atagattagt caagattgca gtaacaacta acgaataagt
    16801 tggggcattt tttttattcg tttttcccca acctttcggc aacagaccgt ctcgagccat
    16861 caacatcgtt gtttctgctg ggagcatcgt ccaagacaac caagaaccaa tgatcgaaat
    16921 aatcaagccg atattgatca gcgctgctcc ccaatttccc acgattcctt ttaaaatatt
    16981 tgccatagca ggttgtgaaa tagttgctaa ctcttcttga gataagacgc cgtatggcaa
    17041 gatcgaagca aggatataga taaacaataa acaaagcaga ccaatgatcg atgcttgctg
    17101 ggcttctgaa cgtttcttcg cgcggttggc taaaacactt gcgccttcga tccctacaaa
    17161 gacccacatc ataaccatca aacaaccttt aatctgcaac cagatcgttc cttgctgccc
    17221 tgttccattc actagattat cagatacgtt accccaaaaa tcagcagtga atatattcac
    17281 tttaaatgcg ataaatacaa atattaaaaa taggaataat ggcactaatt tacagatcgt
    17341 cacgattgta ttgatgacgc tcgctccttc aactccattg tttactaata aagtcagacc
    17401 ccaaataaaa atacttgcaa ataaaataga aggaacattt tgtccacctt tgaatatcgg
    17461 gaaaaattct cccatggcgc tcatcagcat cgttgcaaag gcaacatttc ccagccacgc
    17521 agacaaccag taaccccaac cactgatgaa gccacctaat ttaccaaatg aagcttccgc
    17581 gtaaccgaaa ataccaccat ctagatctgg acgtttttct cctaaatgat tcagcgataa
    17641 taccaaagct aaaataccaa tcccaacgat tatccatgaa aggatcgctg gccctggagc
    17701 tgcagaacta gccagatcac ttgtgatccc aaacacaccg cttccgattg acgaactgac
    17761 aaccagagca accagtcccc atttgctaat acccgtcgat ttcttttcca tttccatcac
    17821 cctcacttat aaaattgaac aaatcacttg caaaagattc ccttctattt tgcaactgct
    17881 cttgcttaac aaaaagcaac tttattcata ttattggata ttatgaactt tttacacaag
    17941 tatttcaagt ataaaatgaa taaaaattaa ttttattgca aaaaaacagc tatgctatcc
    18001 aaaagaaaag gtgtttcttt tgttagccat agctgttttg attcatttaa tatcgcttaa
    18061 acgtattgta aaacttttgt ttcttgatat gcgtggtcga tcaaaccacc acccagacat
    18121 tccattccat cataaaatac aactgcttgt ccaggagtga ttgcacgtac aggttcgtcg
    18181 aatacgactt ctgcacgatt atcatccaat aagcgaactg tcacaggaac gtcttgctga
    18241 cgataacgga atttcgctgt acacttgaat tcttttggca ttggttcatt cgtcgtaaag
    18301 tggatttcac ttgcatccaa gcttgtggca tacaatgcag gatgatggaa cccttgcccc
    18361 acatataatg tgtttgtcgc tagatctttt cctacaacaa accagggttc ttgcgaatct
    18421 cctccgccac cgatccctag tccttgacgt tgaccaatcg tataatacat caagccagca
    18481 tgttgtcctt tgacttcacc atcaagagtg accatatctc ctttttttgc tggcagatag
    18541 ttgctcaaaa attgtttgaa gttcttttca ccaataaagc agattcccgt tgaatctttt
    18601 ttcttagcag tcgcaaggcc tgcgcgttca gcaattgccc gtacttctga tttttccatg
    18661 ccgcctagag ggaacatcgt ttttgaaagc tgttcttgtg ataattggct aaggaagtaa
    18721 gtttgatctt tattattgtc tactccacga agcatgtgga ccacgccgtt ttcatcgcga
    18781 gtgacttgcg cataatgtcc agtagctaca taatcggcgc caagatccat tgcataatcc
    18841 aagaatgctt tgaatttgat ttctttgttg cacatcacgt ctgggttagg tgtacgtcct
    18901 gcgcggtatt cggctaggaa atattcaaat acacgatccc aatattcttt ttcaaaattc
    18961 acagagtaat aaggaatccc gatttgagca gctactttcg ctacatcctt ataatcttcc
    19021 gtggccgtgc atacaccgtt ttcgtccgtg tcatcccaat ttttcatgaa tattccgatc
    19081 acgtcgtatc cttgttcctt taacaaaagt gctgttacag atgagtcgac accgccgctc
    19141 atccctacga caacgcgtgt tttgctgttg tctgtcatga tatcaccatc atttcaatta
    19201 gattctgaaa catctacgag ttgaaggtcg caacttttca gtattttaca ttatacgtca
    19261 tatttctgaa aatttcatcc cttaattatc aagtcgtaaa aatactgttc tactggacct
    19321 attcagtaca caaacatgat agtcaaccaa aaaatcactc atcttttgag cattcgatat
    19381 aaaaaattgg catactcata aaaagggcca gcctttcggc aataaggaat aattttgtaa
    19441 attgtgaaaa actatttttc aaaattgctt cttatcgctt aaagctgcac gtctcattta
    19501 caaccttttc tttttagatg ttatgagttg ctcagataag tgattttgtt tactctaaga
    19561 aaaaagggag gcaagagata catgaattac tttaccagtg atatgcactt tttccatgaa
    19621 cgcttattag gaaaaaacga ctttgctccg cggctctttg caaatgtgga tgaaatgaac
    19681 caacagttga tcactagctg gaatgcagta ataaaagaaa ccgaccatgt ttatcatcta
    19741 ggcgaccttg ctatgcatcc gcaatatgaa aaagcaaatg cagaaatttt ggaactgatc
    19801 actcaactgc aaggaacaat ccacttgatc aaagggaacc atgacagtcg tgcttttttc
    19861 cgttatttag aaaaaaatga tcctaggctt actgacggaa gtcccaaatt ttatttttat
    19921 gatgtaggtg ccatcgttaa attcgaccat caacaatatt acttgactca ttatccgatg
    19981 ttgctcgggc ctaacgacac tatccgcaat cttcatggac atatccatca ttacagcgta
    20041 cctatcgaga acgatgtcaa tgtaggcgta gacgcaccgg aaagagaact cttaaaggaa
    20101 aaactaccat ttggcactcc gttatctgag caacaaatca aagaaatcta tgaagcaaag
    20161 aggaagtacg ataggtcgtg aaaaaactgc cctatatcaa gtattaaaca aataaagata
    20221 attactcata tttttcattt gagtaggctt attgccacag gaacattagg atcagaaatg
    20281 gagttgtaac aagacttctg tcacaactcc attccatact attcgtcttt ttgctcatgg
    20341 tgttctttta ccaatttttt ctgtaattct ttatcataat ttcgagcagc tgacgttaaa
    20401 aataaaacga ttccgcataa taaaatcccg attccagaaa acaagaacat tttttctact
    20461 cctaaacgat cagctaatgg tcctgcaaat aataatccaa ttggacctgc caggttcatc
    20521 aaagagttga agttccctaa gacacgacct aaaacattcg attcataact ctgctggatc
    20581 attgccatca gcagtgtatt gaaatatggc gttgcacaac ctgctcctgc attcaagata
    20641 agaaagtaca agaacccttg actatcgttt ggaaccaatc cgcttgcacc gatcgtcagg
    20701 cccataatga tgtaggctat aataataggt ttcattcggt ctttccatgt tcctataaaa
    20761 ctgatcagtg caccgcctaa gagcattccg actgcgtaga ctacttccac tgctcccgcc
    20821 tgtccaacgg aaccaccaaa gtaatctagc gtcatcaatg gatacagact gattgctggc
    20881 atgaacaaca gcatcacaaa tgcaccattg atcgttatgt accataaccc tttgttatcc
    20941 atcaattgct gcagcccaaa ttttgcatct ttaaaaatag taagcggaac ttccaatatt
    21001 tcaggagaaa cttttgggat cttcacaaaa atcaataagc cgacaccaaa aactgccccc
    21061 aatacatcta ataaaataag gtaattgaca ggaacgactg aaaacaaagc cgcacctaga
    21121 gctggcgcaa tgatgaaatt cgctgactgg accattccta actgtccatt cgtccttgtt
    21181 atgtgagaag atggaacgat tgtcggcata atcgactgga tcgttggcat ttggaatgtt
    21241 tgtgcgaccg aacgcataaa caaagacaca aaaactagcc aaatcgggaa ggattctgaa
    21301 atcgttccga ctactgctaa aataagcgcg aaaatcgcta caataatatc cgtgacaatc
    21361 aaaagagctt ttttatccca gcgatccact agcggtccta caaatgggct tagtaaaacc
    21421 atgggaatca ttcctagtaa agtagcaaaa ctcaaaattg tcgccgaacc ggtttctctt
    21481 gtcaaatacc agatgatcgc atattggacg accatactag tgattcctga caaaaactgt
    21541 cccgataaaa agaacaaata atttctcttc caattcgtta aaacgaccga ctgttcattt
    21601 tccataaaca tccctctttt ctttttcatt ttgtatagcg tttgcacaac aatcattata
    21661 cgggattctt ttttcaaaaa ataccttttt ccctaaataa caatcgtttc aatttaaatt
    21721 tctttactta gaaacaataa atcagcaaaa tattaaaaat aacaacatgt gttaaattta
    21781 aaaataaaaa agacaactaa tttgcgtcgt ccttacaaag ttagtcatct aacaataggc
    21841 cgtttcaaaa ctagttgtct ttttatatcc acagatcatt cgactttttc gaataaccca
    21901 cggctaatca tcccatccat cagaaaataa aatttatctt ggctcatttt ctgttttgga
    21961 tctttgaaaa tattgactgc tttcaatcca tttgctgtag tgatcgacat tttcaatgtt
    22021 tgaatatctt ttgatacagt gatttttaat ttgaatcctt ctttgctttg cggcgtggca
    22081 tctaatggtc ggatcaattg ataattgcct ccgtttgttt ctgtaaatcc attatcgcgc
    22141 aatgtatatc tttttgcatc aggatgcaaa cgatagctaa ttggtgcgcc cagtaccgtt
    22201 gctgttgttt caaatgccat gattttcacc tcgataaaat tagtttctct ttattataaa
    22261 agtttatcct gatttttact aggtttttca gttaagttcc ctaaaaaatg aaggcgttct
    22321 ctcagacatc tgttcatata agaatgactt cactagttat tttttgacag cacgaactaa
    22381 ttgatcaagg aaatactgga tgtcgtcttc ggtatttccc aaaccaaagc tgatacggat
    22441 ggattctttt agtatcggtg tatcttctcc atacattgct tctaatacgt gtgaaggctc
    22501 gatatttcct gctgtacaag ctgaaccagt agaaatagcg accccattaa gatcaagctt
    22561 catcagtagc aaatcatttg cttcgccaat taagcgaaga ttcaacacat gagggagttt
    22621 attcgttaaa tcaccattta cttgataagg gatttcgttt gcttctaatg tatcaagaat
    22681 caattgctgg aatcctttat atttgttgtt acgtgcttca cgttcttcag atgacagcag
    22741 ttcaactgct tttgccatac cccagatccc tgctaaattt tctgtacctg cacgccgctt
    22801 ttcttcctgc tccccgccta aaagcaatgc agggatattt actccgtctc gtttatataa
    22861 gaaaccgacg ccttttggcc cattgatttt atgagcagag atacttaata aatcgattcc
    22921 taattcttct ggatggatcg tttggtttcc gtacgcttgt accgcatctg tatggaaata
    22981 agctgggtga tccgctaaaa gttcaccgat ttctttgatt ggcatcaaat ttccgatttc
    23041 attgttcccg tacatcacag agaccaagat cgtatcttct cgtaacgctt ttttgacctc
    23101 ttcgatcgac agattccctt tttcatctac aggcagatat gtaacgtcaa acccctttgt
    23161 ctctaaatat ttcatggtat taagaacagc aggatgttcg atagctgtag tgattagatg
    23221 tctgccttct ttttgacgcg agaacgctgt ttctaagata gctgtattat ccccttctgt
    23281 tccaccacta ttaaagatga tctcgtgagg ttttgcttgc agactgtctg caatgatttg
    23341 tcttgctgtt tccaattttt catgcgcgtg gcgaccaaat ccatgtatgc ttgaaggatt
    23401 tccaaacgtg tcttgcatga ttgccgtcat cgcttcaatt acttgtggat gcatgggggt
    23461 agttgccgca tgatccagat aaatagtttt cacttcattc atcccttcca aattattgct
    23521 aggcacattc tagcataaaa tagcgaacaa accaaagaag agctcatttt tgtctagagg
    23581 acgtttcatg ggcatagaaa aaaggagctg tgacaaaagt cttgtcgcag ctccttgaag
    23641 ctgctcactt gtgtcacaac ttctttccct ctttttttgt ttattcgaat tctttttctt
    23701 ccagacggaa taacggactc atcggtgtat tttcatggat gcgtttgacc gcttctccca
    23761 ttaattctga acatgtaacg attgttaagt tttctggatg acgattttct tctgtgaaaa
    23821 cagaatcagt gatacaaata tctttgattg gtgcattgtc taaaatactt ttcgcatgat
    23881 cggacaataa tccatgtgac gcacaggcat atacttcttt tgcgccgttt tcttttaata
    23941 catttgctgc tcgtgcaagc gttgctcctg tgttcaagat atcatctacc atgatacatg
    24001 tctttccttg aacatcaccg atcacataac caccctcagt tgaagcatca tctgcatgat
    24061 ctacgatggc taatgtgctg ttcaaatatt ctgaaagact acgtgcacgc tgaacaccgc
    24121 tgttttttgg cgaaacaact acgatgtcat ctcccgtcag acctaattga cggtaataat
    24181 gagcaaacaa cggcatcgta aataaattat ctacaggaat atcaaagaat ccttgtactt
    24241 gaaccgtgtg cagatctaaa gtcagtactc gagttgcccc tgcttcttcg atcaagttag
    24301 cgatcaattt cgcagtgatc ggttcatgag gtttcgccgt gcggtcttgc ctagcatacc
    24361 catagtaagg caatacgaca ttgatcgttt tcgcacttgc tcgcttcatt gcatcgatca
    24421 tgatcagtag ttccatatag tagtcattga caggtgcatt cgttgattga acgatataca
    24481 catgatcccc tcgaatactt tcttcgatat tgatggaaat ctcgccatca ctaaattgct
    24541 tcacgacgct tttacctaat tctgttccga acactttcgc gattttttca gctaatggac
    24601 ggttgccatt caaactaaaa atcttcaacg tgtcatcctg atacttatta ctcatgtagt
    24661 cctccccaaa acttctctat tcttcgatag tttaacatat ttttccaaga ttttctgtta
    24721 atttcagcaa attcttaagg aagtgaaact gttccgttac tccaactggc aggaatgact
    24781 ttatgataat cgccccagtt gtcgtgtact ttgtaataac gttctcctgt ttcagtttca
    24841 aaataagcgt acgctgtcac ccaatgattg ccatatgtac tgccaagtac tttcaaaata
    24901 ccaatcatca caggtttgcc ttcacgtata cgttttgtag ctcgctgcca tgaacctaga
    24961 agagttgctc gtgcacgctc atgattgcca ttcttcttta aaaaactaga aatccctgta
    25021 ctaacctgaa aaggaatcgt aggaagtcct agtggttgga tctggctacg caatgccttc
    25081 gtcaaaacca acgaatcagc cgtatttttc ttgcgaatct catttggaag catccacccc
    25141 ttacgatagt cttgataata ggcaaggaga actgctgccg cgtaagtacc acaaagatag
    25201 cctgaggggg tagcccattt cttatacctc aaaaaacgtt cttctggcaa tcccacccag
    25261 caatttgcga gttcctttcc tgaccttttt tcttcgatca aaacgggaat atcttctttt
    25321 ctgttgatcc atctagataa ctcgattggc tcttcattga tcagcttcca ttttttacaa
    25381 gaaagaccct cttgataagt atattttgct ggagaatatt ctaccggatg tcctgattga
    25441 tcgataatca cataactttg atcttcaaaa accagagcta aaaaaagcaa tttacttttt
    25501 cttgactgca gctgctgagt gctggctaat tttttaattt ttttatctac tttgaaatat
    25561 aaaggtttat ccactacttg attcagttgg gatcgcctcc tttttttcat tataagtgaa
    25621 ggattgaaaa aaacaaatca gtttgattgt tcgaattttc aattttttat gttctatttg
    25681 ttaattcctt cattttgtaa gataatgggc acacgaaaca aaaaaggagc gatcgatgaa
    25741 tgaacaaaga acgattgaaa caagatttct atgaagcagt caatgaagaa tggcaaaaaa
    25801 cagcaaaaat ccctgcagat aaaccagcta caggcggttt ccaagattta gttgacggga
    25861 tcgaccaact tttgatggga gaaacagacg atctgcttgc ccatccagaa aaagtgtctt
    25921 cagaaaaaat gaaacatttc cttgcatatt atcaactggc aaacgattat gaccgaagaa
    25981 atgagttgca tgctcaacca cttcaaccta taatcgaaaa agttgaatca ttgcagtctt
    26041 tcgacgaatt gaatgagcaa tttccagaat ggctgttgga tacattacca ttgccattta
    26101 atctggatgt agatgcagat atgaagaatg cgcaaacgaa cgccttcttt gcttatccgc
    26161 cttctttatt ccttccagat aagacgtatt atgcatcaga ccatcccaac ggtgcacaac
    26221 taataggcgt tttctttgat atggctgttc agttattaga gcttgccggc aaagaaaaaa
    26281 gtcaggcaga agcaatcacg gaacaagcag tgcaatttga taaattgatt gctcctcatg
    26341 taaaaagtgc agaagaaaac gcagattaca gcaaaatgta taatccgcaa tcttttgata
    26401 catttattca atacacagat aaactggact tgaaaaaact tgtcacgggt ttgattggga
    26461 caactccaga taaagtgatc gtaactgatc cagtgtactt cgatcatttg aatgacatcc
    26521 tgacagaagc tcattttccg ttattcaaaa gctggatgat cattaaaaca gtacgttctc
    26581 ttagtggtta tctatcagaa gaattccgcc aagtcagcgg aatctattct cgcgtattgt
    26641 ctggaacaga cgaagcaatg cctcagaaaa aagcagcgta ttaccttgcc tctggacaat
    26701 tcgatcaagt agttggcgat tactacggaa aaaaatattt tggcgaagct gctaaaaaag
    26761 acgtagaaca aatggtgaaa aaaatgatcg ccgtttataa aaaacgtcta gaagaaaatg
    26821 actggcttgg ggatgcaaca aaagaaaaag ccgtcataaa attaaataac ttaggtatcc
    26881 aagtaggcta ccccgataag atcccagcat tattcgacca gttcaaaaca gtacctgcag
    26941 atcagggtgg tactttgctt tcaaatactc ttgttttcag caaactcaca ttaaaagatc
    27001 gtttcagcaa atggaacaaa ccagtggatc gttcagaatg ggaaatgagt gctgacacgg
    27061 tcaatgctta ttatcatcca tttcggaatg tgatcgtctt tccggcagcg atccttcaag
    27121 caccatttta cagtctagaa caatcaagct ctgctaatta tggtggaatc ggagctgtta
    27181 tcgctcatga gatttcccat gcatttgata ataacggcgc tttatttgac gaatatggca
    27241 acttgaacaa ctggtggaca gaagaagatc ttacacaatt tcaaaacaaa gcacaagcaa
    27301 tgatcgaaga attcgatggt ctgccttttg ctgacggaaa agtaaacgga aaattaaccg
    27361 tttcggaaaa tattgctgat gcaggcggtc taagctgtgc attggaagca gcaaaaacgg
    27421 aatcagatct ttctatcgag gaattttttg tcaattgggc aacgatttgg cgtacaaaag
    27481 caaaaaaaga ataccaacaa cttttactgc aaatcgatgt ccatgcccct gctaaactcc
    27541 gagcaaacgt gcaaccaaaa aaccttgacg aattctatga aacatttggt atcacggaac
    27601 aagacgctat gtatctagcg ccagaaaaaa gagtgcgaat ctggtaagag gttgtgaaaa
    27661 agccgcttag tttcaagtag taagaaaaat tttgtgaaaa tagctttcca catttttgca
    27721 taaatttgac ttactactga gaaactggct tttgaacacc gtttatcgag aggttgtgaa
    27781 atcagcgtcc tgacctgagt attagagaaa aaaacggaaa aatagttctt catattttgc
    27841 cgtttgttga gctaataccg agggtcagct gattgaacac cgtttagtgg agagattgtg
    27901 aaaaagctgt cctgcatcaa gtaataagaa cagccaatca aaagcagcaa ggagaacctc
    27961 atctataaaa agatagaagg aagtgagaca tctattggtc tcatttcctt ctatttttac
    28021 tttcctcagt caattgtttt acatcataaa aggagaaatt ccacttattt ttttcgctgt
    28081 ttcatgacat aaacaactac accgattaac aaaattcctc cagctaatgc tagcaacggg
    28141 ttattaaatt ctcccgtttt tgggagtcct tgagtgccat ttttttcact ttcttttgct
    28201 gtcctatccg gatgagaagg ttttccattt ggttttccat ttggttttcc atttggtgat
    28261 tcatttcctg gattttctct ttctggtttg tcatttcccg ggggcacatc ggcagtttct
    28321 cgcacagtga tcgctttttg ctgggtaaca gattctgtat gagcagacca tttttcccca
    28381 tcaaatattt ccgaacgata agtgacttct agcgtatatt ctccttttga aggtgctgaa
    28441 aaaatagcgg tatgattaga aaattgagca cttgactgtg tttcaacgat ttggatcttt
    28501 tctgggaaat aacgcatatc ttcaaagaca ggcgttcctt gatttggtgt gaaagttgac
    28561 acaaaaactg taaaaggctt cagttcaatg atatttcctt ctgcattctc cgccacacca
    28621 tttgcttctt gtataataat cggattattt tgttcatttg gttttgtctg atttggttct
    28681 tgtacgattg catattctgg atactccgaa gacggtgagg tttctccgtc aaaagtagca
    28741 cctacagata gtggaagacc atctactctt cccttttctg tttgacgatt ctccggtttg
    28801 atttgcatca atccatggac atggatgctt ccattcgcat agcgagtaac aggctgctgc
    28861 ccttcttgcg aatgtgtatt tagagattcg atccaatctt ttgatacggt atgtccaaga
    28921 gtattttctg attgtttctc tcgttcattc caatagtagt tcaacgagtg atagatttga
    28981 tcttcgtttt gattcaatgg gcggatctgc tctctcatct caagattttc tgttcggaaa
    29041 gataagatac cagaagcatg gaagtctgtg tttcctgccg aagaggtata aagagccaca
    29101 ttatatgaac cgttattaaa acttgtactg ctattgacga taatatctgt tccgctattg
    29161 gaatcgattc cttttgcaag attttcgaaa gacaaactat tgatcaattc atgagggccc
    29221 gataaagagg aatcacccat tttgaatcca ttaccgttcc cttctccttc aactcccggt
    29281 acccaaccgt ttcgataagc aactgagttt ttgatgacta ctttcccgat tgaacctgtt
    29341 tcatttttag caaaaagatc ccaaccatca tctgcattat gataagcgat acaaccgtca
    29401 aatacattcc cttctcctat tgtcagtttg gccgcaaatc catcggcatc ttcaaatcct
    29461 ggatcggcat tttcaaaaga tgtacagttc ttgactaagt tatgcgctgg ccatgcttcg
    29521 aaaggatcat ttgagctacc actgatttgg attcctgtat ttccattccg ataagcatgg
    29581 atctcttcaa tcaaattatg gtttccagaa atctgcaatc ctttttgcat agcggcacta
    29641 tttgtaacgt caaacccacg taaaacccag taatgactaa acagtgtcat cccatttcca
    29701 gttcctttaa aatcaagtac aggtcgcttg ttttctggat ttttctctgc aatcaattga
    29761 atcgggtttt ctcttgtccc gttaactcct tttggaatcg tcaatcctct ttcaaaggaa
    29821 taagttccag gagccaggac gattgtctgc ccagcatatg cgtatctcaa tgcttgcgtc
    29881 agagataacg gattttgtct gcttccgttt cctgtatctg acccttccgg tgttacataa
    29941 actgtcgaat agttaggttt acggtagtca actgtatgca gaatctcttt tgtttcataa
    30001 ctagccatct ctacgtattc ttctggcgga tagtttttat ctggtgtaaa actgaaagta
    30061 aattcgttcg ttccttccat cagttttgtc tgataatcaa attcccgatt tgcagtgatt
    30121 gccaagtctt ttgcgttctc aagtacctct cctgttgctt gatttttgat tgttaataat
    30181 ccgtcagcat ttgctctaaa ggacatagta tggtcttggt ttcctgaatg attactagag
    30241 gtcacagtgt aaatcggatc aatcaagcga gtaagtcttt cttgcccagg aggatctgtc
    30301 gcaggatccg agtaagcaac ttcgattcct tctaccttga tcgtcatatt ccttgctgca
    30361 gcaaatcctg cataaataac cgattcatct gaagcgtata atttttccca gtcatacatg
    30421 atgtcagaag ccatttcttc tcctgtttca ggatcgtaat aatatgcctc taaaccagta
    30481 ttcgtttttt tcatctctac gtccagttta gtaatcgagt tcgtggccgg aaacagattc
    30541 ccatgaccgt ttccgaatat attataagaa cctgtttctt tttccaagaa ccctgctgaa
    30601 gtctctaaag gtgttgtttc cactgagaca ctcccaggag ctggcgcagc ttgcggatct
    30661 tcagatgata ttcctgtgat tgcccgtgtc cctaatccaa gtcgcatcgt atatttgctg
    30721 ccgctcgtgt tgaccacttc ttgtctatcc gagtcccaga catattcgat ccgactgcct
    30781 agtatggcaa atgaatttga ataaaatgcc tgcccaaaca aatgatcttt tggtactgcg
    30841 tctcttacca ttaaagcaaa tccttcttgg gcattcgtat aggtccaaga ttctatttcg
    30901 atcgtcgccc gcatcctaaa gttgatgtct ttggggattg cttgataata ataggtcatt
    30961 ccatctggtc cgcttgactg gaattttccg ccgttattcg tggaagagag ccgcacgccg
    31021 tcttctaatg gttcaatggc atacctacta gcacttgtgc tttctccgaa aacaacccct
    31081 ttccactctt catttgcttc ttcagattgc ttttttgtct tttcattttc tgattctttc
    31141 atcataggat catttccttc ttccgtatcc atatcttcac tagttcttgg tacttcctcc
    31201 attgttgaca tcccttcaat gttcacgtgt gcattttctt cgttcacaga ctgttgttcg
    31261 ttagcagcaa cttcaacgac agaaattaaa accggggtac tgagcataag gagattcatc
    31321 attagcgcac tgtattttat acgttttttt aacaagtgta ttcctcccgt aacaaattag
    31381 aaagcgttta cttaaagtat tacctaattt atttttactg tcaataaaaa acaaaattat
    31441 aataagtgta ttttataaaa agaaaaaata taacttaagt tgttgataat aaagagattt
    31501 attaacggaa aaagaataag tttttttaaa ataacgtata aaaaagagca taaaacaaag
    31561 tcgtttgttt tatgctcttc ttttattatt ttgtgctttt tattttatca aatcactttg
    31621 tttttttata aaatttctgc gcctagtgtg gactcaaaat gtctcaatgc ccattcatgt
    31681 ccaacgggat cgaaacttgc cacggaatct ttgaaaatat ggagtttgta tcctagatta
    31741 tacgcatcga ctgctgtatg caacacacag atatctgtac atacgccggt caaataaata
    31801 tctgtgatct ggcgttctcg caaacggatg tctagatctg ttccactaaa agcggaataa
    31861 tgccgtttgt ctatccaata aacattttcc tcttgctcat agtcttggta taaacttttt
    31921 aaagagccgt acaattcccg tccacccgtt cctatcacat tatgcggagg aaataagcgg
    31981 ttctccggat gaaaggaatc ttttggatca tgcgcatcaa tggcaaaaac gacaaaatcc
    32041 ttttgatcaa taaacttctt tgtatgagca gtcagctttt tttcaattac ttgtcctgct
    32101 gtcccagtag tcagctttcc atcctctgca acaaaatcat atgtgtagtc aatcgagatc
    32161 aatgcgttca tcttagtcct ccttatacga gatgtttgac aaattcgatc accatttctg
    32221 ctgatcgttt gcctgcgtct tcgataaatt cgtcaaagct ttgtgtcgcc gagtgatctg
    32281 ctgtgtcgct cattgcacgt acgatcaaaa atgggatatt gaactgacga gctgtttgtc
    32341 caacagcggc tccttccatt tcgcaagcta atgcttcagg gaaattcgtt aagatttctt
    32401 tgattttatc tggcgagtcg acaaatgtat cacctgtaac gatcaatcct tcttttgcgt
    32461 tcaaattcgt tgcttttgct gctttaacca tttcactgcg caaatatgtg cttgcttcat
    32521 aatatagagg cattcctggt aattgtcctg ggttgtagcc aaatcctgtt gcatctgcat
    32581 caaaataagc tactttgtct gatataacga tgtcacctac ttgtaagcct tcaccgattc
    32641 cgccagctga acctgtattg atcaccatgt tcacgccgta ttgttggatc aacagacttg
    32701 tggtaataga tgctaagact tttcctatac cggaacgtac gacgatcact tcgtggttac
    32761 ctaatgaacc tgaaataaat aaagcgcctg cgcgttccca tgataatggt tcgcttaggt
    32821 tctctctcaa aatttttact tcttcttcca ttgcgccgat aataccgatt ttcatctttt
    32881 taattccttc tttctatata aatgcgattg ctaaaaaaac cacacataac attaggataa
    32941 caataataag agatttcatc aaaaaagagt tccatttggt cgtcttttcc cgttcgctga
    33001 tccttgtttt cgtgattggt ttattctttt tgctttcttt acgataaaag ctggcaatct
    33061 ttttttcttc ttgctgataa gctgtttctg cttttcgctg tttttttaat gactcgcttg
    33121 cttgtgcttg ttgtcgcttg cgaagttcgc ttcgcgtaat aagcggtcct ttggccataa
    33181 gccgatccct ctactttcct ttggtcaata gttcccagta ttgaatcgca taaatcgtct
    33241 ttgcatcaca aatcaactga tctttcatcg cttgttgcgc ctcttcaaga gttagatgat
    33301 acaactccag tacttcgtct tcatcttgtg ctaaaggatt ctcgaccttc tctacccctt
    33361 gtgcatgata aatatgaagg acttcatttg caaaacctgg tgaaagatac atcgaagtaa
    33421 gatggctcag cgacttcgca cgatagccag tttcttcttc taattctcta gctgctgtca
    33481 tttcgggatt ttgtccttct cctggatcga tttttccagc tggaatctcc aaaatcactt
    33541 tttctaaagg ttttcgaaat tgtttgacaa gaagcagacg atcttgttcg tcaaaagcaa
    33601 tgatcccgac accgccagga tgaaatacca gttctctctt cgaagttcct ccatctggca
    33661 aacgaacttc gtctacagca acatcaataa tttttccgct atagatttct ttgcgactga
    33721 ttgttttttc ttcaaattgc tcattgttca gcatatcttc tcctgctttc tttgtaatca
    33781 taactgcttt tttttcattt ttcaattttt ctcaaaaact ccttattagt ttaccataga
    33841 taaaccttag attttctcta aatatagaaa atccttcttt agtccgatac tctttctagt
    33901 agtccgtatg ctaaaataag tatgtaatcg aataacgaaa agaattcaat actcaacgat
    33961 aaatgacatg gagggtttat tatgataaaa cgaaattggc cgtggcttct agcattggtc
    34021 ttgctatttc tctttgtccg aaacaatagt ttttcttttg ttctaggact tttattgata
    34081 ggtgtagttt tagttttgtg gggactcttt ggttcgcgca ggaaaaaggg aaaacaagaa
    34141 gaaattcctg cactgactga cgaacttgaa actcactatg aaaaaagcgg tatgacagcg
    34201 aatgaaattt cattttttcg acaaacaatg aatcaaacaa aaaatgagat caatcaattg
    34261 caaatgaata tgcagcagac agccaaactt aaagcaatcg atctccgcca tgatccagtc
    34321 aaagcagcga aagctttatt caaagaattg gtgaaagaac caaaccgact gcatgaagca
    34381 agtcagtttc tttatacgca tctgccgaat ctagttgatt tgacaaataa gtataatgag
    34441 atcaatgacc atgagatcaa aaacaaacag acctatgaaa aactagaaga aagcgcgcag
    34501 atcatcgacc agctgtcagc tttaatcgca caagattatc aaaaattcgt tgctgaggat
    34561 ctagatgata tcgacgtaga gatatctgtt gcgaaacaga gcttaaagcg tgataataaa
    34621 tatgaaccag aacaaaagga ttaactcttt tgttcataaa agaagactcg gaacattcag
    34681 atgatgtctg gctgtttcga gtactttttc taaagtagag acattcatgt aagaatcgag
    34741 aacagattca acaaggagga attttttatg gatcataaac cgactgaaac aaaagatgtt
    34801 acaccagtta acgatacact tgaagattta ttgaacaacc cgttttcaac tccaacagat
    34861 acgctgacca cttcacaaca agcggagatt gatcagctcc aagagcaaca gacagctgct
    34921 cgtttaattg acaaactacc ggcggaacgc caagaacaag ctaaacagct agcagcaaaa
    34981 atcgatgcta atgatgcaca gtctgtcatc agctacggat cggctgccca agcaaaatta
    35041 agtgaattct cacaatcgat gttgaatcat gtgcaagcac aagatattgg tcctgtagga
    35101 gattccttaa ctgaactgat gtatcgtctc caagaagcca atcctgacga actgcgtgcc
    35161 ggagaaggga acatcttcca gcgtgtcttc gggaaggtca aacaatcgat ctatgaagtg
    35221 acagcaaaat atcaaaagat tggtgcacaa attgacaaga tttcagtgaa attagataaa
    35281 gaaaaagacg gtctgctaaa agataatctg atgttagaac agctttacca gaaaaacaaa
    35341 gactactttg atgcactgaa tatttatatc gctgctggag aattgaaaat ggaagaactt
    35401 caaacaacga tcattccaga agcgatgaaa agagcagaag aaactggcga tcagatggat
    35461 gttcagattg ccaatgatta cacgcaattc ctagatcgtc tggataaacg tacgcatgat
    35521 cttcgcttag ctagacagat cacgatccag caagcaccac aaatccgttt gatccaaaac
    35581 acaaatcagg ccttggctga aaagatccaa gcatctatcg ctacagccat tccgctgtgg
    35641 aaaaaccaag tcgtgatcgc attgaccttg cttcgtcaaa aagatgcagt aactgctcaa
    35701 cgccaagtct ctgaaacaac aaacgactta ttgaagaaaa attcagaaat gctgaaaatc
    35761 tcagccatcg aaacagcgaa agaaaatgaa cgtggaatcg tggatatcga gacccttcaa
    35821 accactcaaa atgatttgat cgaaacaatc caagagacat tgcgtatcca aaaagaagga
    35881 aaagaaaaac gtcgtcatgc agaagtagag cttggacaca tggaagaaga tctgaaacaa
    35941 aaactgttgg atttaaccca atagatcacc tttcgcttgt tactaaaaca aacgcccaac
    36001 aacagtttat tacaactgtt gatgggcgtt tttcttatct ttcttctaac ttctccattg
    36061 gagtctattt ctcattcatc ttgctgtgtc catagccata gccaaaataa atgatcagtc
    36121 caataaccat tacgataccg aacacgatcc atgtcacagt ttgcagacga agcatcaata
    36181 caatacaagt caagatggag acgattggca atagcggaac gaatggcact ttgaattctc
    36241 cagcttttgg tttgccaaac atttttctca acttcagtaa gcctagacta acaagcatca
    36301 aataggcgag cgccatgata ttcgttagtt ccgctaatac attcaatggg aaaaatccgg
    36361 caaagaatac agctgccaca ccagcggcat aagtcgcttt tttcggtgta cgatgctttt
    36421 gatcgatttc tgtcataaac ttaggaagta agccatcctt gctgacagca aacagtaaac
    36481 gagcaagtga atacatcatc gagatcgtta ccgtcagtag cgttaaaatt gcccctacag
    36541 cgatcaccgc gcccactgtt ccatgtccta catacctcat tgcaaaagcc actgggtcat
    36601 tgactcctag ttcagtatac ggaacgattc ctgtcaagat cagcgtcacg atgatgtaaa
    36661 ggacagtagc aatcagtatc gaaccaatga ttcctcttgg cacatctttt tgcgggtttt
    36721 tgacttcctc ggctgccatt gcaacggcat caaatcccaa gaaagcaaaa aacacaagag
    36781 ctgcaccatc tagcacaccg gaaaaaccaa aaggcatgaa tggctgccag ttatcaggtt
    36841 taacgaaaaa tattcctaca atgataaaca acgcgatgat accaaatttg acatatacca
    36901 tggcattatt caaacgtaat gctttcttgg cttcaagcga cacgatgtaa gtgacgaata
    36961 tcactacgag caccgcaatc aagtcaatgt atgtaccatt ttccggattg tacccgccag
    37021 ttaatgcttg tggaagttcg gcccctaaac ttttcaaaaa accttgcata tagccagacc
    37081 atccggaagc aacagaggaa accgctagta aaaattcccc gatcaacaac caccctgtca
    37141 gccaggcagc aaattcacca aatacaacat acagataggc atatggccca ccaatcactg
    37201 gcactcgcga agcaaattct gcgaaactta gtccagacaa aatgataacg attgcagcta
    37261 agacaaatga aagtgacagt gctggaccag cattttgatt ggccgcaacc cctgtcacca
    37321 caaatattcc cgtaccgatg atcgcaccaa ttccaagcat gatcaaatca gacgttttta
    37381 gttctttttt catctcactc gtatgattga gattgatctc tttcttacga aacaaatcca
    37441 ttgaagttcc tccccatttt aggttggaaa acagcgatta aactgttttc atatacccta
    37501 aaaggatacc acctaaaatg actaaaaggc aaccaacaat aacataaatg agctcttttt
    37561 tcgtttttct ttcgccaagg atgaaaatcc cacctaaagt agagataatg atccccattt
    37621 gtgaaagtga gaagccaaca gctaaaccaa gtgatttgac tgttagaagc atgcagatgt
    37681 ttcctaagcc ccataataat ccacagatca tgtttttcca cacaaactga tcgactttaa
    37741 ctttacggaa agcaaagaag cttgcgccta agatcattcc gatactttga ggtaagataa
    37801 ttgacatcgc atccaaattc gcccagttga cgatgatggt atatacacca taaccaatcg
    37861 tagagaagat caatgctcta aaacccttac caaaatcaag cattttatta tctgtatcta
    37921 tttttccttc gtcatcttgt cgggcagtca aatacgcacc gcttacaaga agagctaaag
    37981 caataatacc gtatacataa tctttcgttt gtgtccattc atggaagaaa acggctcccg
    38041 caatcgtatt caaaattaat tgaaaaccag tagacaatgg tagccctaca gaaacaccca
    38101 tgtacttcat tccatggaac tgtccatttt gtccaacact ccaagctaag ccggataaaa
    38161 atccgatcaa gaaaatccaa ggggtgatta caggactaac aacgaaaaag acaactaaag
    38221 aaaacagaaa tgcaccgatc gtcattccta gtgtttgttg attggcatcg ccaccaattt
    38281 taccacttac taaaccaata ctaccccatg ccaacatagg gactaatgct attaaaattt
    38341 ccataaccaa tctcctttta tttcacatga taagaaactt atcagcgaaa acgttaacaa
    38401 cacaagcact ttttttcgtt tctaacgatt ttctaacgtt tttcattata aaaatttaag
    38461 attgggaaaa ataaagtcat tgttgtccct tttccttcag ttgattcagc cgtcaaatgg
    38521 atacctaatt tttcggccag attttttgct aaataaagtc ctaatcctgt tgaatgtgtt
    38581 ttgctaagtc gaccatttct cccagtaaat cccttatcaa agatccgttt caagtcttcc
    38641 gctgggatac cgatccctga atctttaact gaaaggctga ctccttgcgc ttccttttct
    38701 atgctcacaa tgatgtttcc gtgatccggc gtatatttga tggcattact aagcaattgg
    38761 ttgaagataa aagcgatcca tttagcatcg gtcaaaacag tatgatcctc accaacgatc
    38821 tcgtagcgaa tatttttttg gataaaataa tttgcctgac tgcgtatcac aggctgaatg
    38881 attcctttta gtccatattc ttggatgagg tagtcccgcg agaaactgtc gagtcttgca
    38941 taatacaaaa cttgttctac gtattcatcg atttttgata attcattttc tagtaatgta
    39001 tacttttgat cgtcaatatc gaactcgatc gaacgaacta gcaatttaga agcggaaagt
    39061 ggcactttga tttcatggac ccatgagtca atataatctt tttggtcttg ttgattactg
    39121 attgctgatt gcattacttc ttggtgttca cggatcagct gattgatata ttcttctacc
    39181 agtttttctt cttctgtcct cccaccactc aaataatttt gcaaagggga agttttttgt
    39241 atgtcggcta attttcccca ccatcttctc ttgctcaagt aaccacccag cagataaaaa
    39301 atcagaaaga cgccctcaat caaagctaaa taagcaattg tgctcaaatc aactttgatg
    39361 tttggcgcca gccacatcac aaagatcgtc aatgcaataa aaaacagcca tcccaagatc
    39421 aatgtccact gatctttcaa atatttaaaa aaattcatct taaccgctca tcctttcagg
    39481 gaacgatata tccctgtcct acttttgttt cgatatatcc ttggatacct gcctgttcga
    39541 tttttcggcg taaccgattg atgttgactg tcaatgtatt gtcatctaca aatcgttcgt
    39601 catcccacag tgctcgcagc aatttttccc gacttaagat ctttccattg tgcttcatca
    39661 aaataaataa tagacgatat tcatttttgc tcaaatcaat gatctctccg ttgatttcca
    39721 tacttccgtt gtcaacattc aacgtaatgc cattgtggct catcatttca ctagataatt
    39781 ctgtgtagtt gtaagaacgg cgaagtaatg cattgatttt tgcaatcagt acatcgattt
    39841 ggaaatgttt tgtcacaaaa tcatctgccc ccatgttcat agccatgatc atatccatat
    39901 tcgtattcct gctggagata aaaatgatcg gtactttcga tacttcacgt attttttgac
    39961 accaataata gccatccaaa acgggaagat taatatctag taatacaagc tgtggttctt
    40021 ctctttcaaa gtctgagaac acttgattga aatcggtcgt tccaaaggtt tcaaattgcc
    40081 atttctcaag ttcctccatg atcaattgtc gaatgatctc ttcgtcttcg actaccatga
    40141 tttttgccat aaaaaatccc tccatctttc ttcttgctac tacaatatca aagaagccct
    40201 tgtgaaacaa gttggcttac ctggaaaatg tcattttagc aaacgttaaa aaaaactgga
    40261 aatatgcgat ttaatcgcgt ttgtctcttc caagcagctt aaatttatta tgttattctt
    40321 aataattggt ctattatctg ttatttttct ttcgttgttt ttgtctttta aattttcgat
    40381 aacaccaata accgaaaagc gttagcacta gcaatatacc tagaaggagt ataagtaatc
    40441 gataaagatg gtattttttt gtctgttcta tctttgaaga gacttcttct gtaaagggaa
    40501 ctcgtcttcc tgtcactagt aatcggtgag tgttcacggt gtaaggtgta caagtgataa
    40561 gtgtgactag atcctgcttt tctctaattg ctaatgtatt tgtttttgtt ggaaggacaa
    40621 caattttctc aacgacttca taagcgagca tccgaccata cacttcaaga tagaatcggt
    40681 catcttgctc catttcttca agatccgtaa agagtttttt ctcagcaata ccgctatggg
    40741 cggtaatcac ggaatgtgta ctctctcctc cagttggaaa agaggtgcct tgcaggactg
    40801 tcgctcctct atctaacaaa agatcattcg tttcatcaaa taaaggcaag ctaacattga
    40861 ttttcggaat atagatggct ccgatcatat gttgttcgta atattctttt cctggatttt
    40921 ggacatttct aaccgcttgc tcaaaaggat ctttgacttg tcccattcct gggattactg
    40981 atgtatgagc aagcgtctga tttttctttt catgcactgc taattgttgc tcatgttttt
    41041 cttctttatc gcgttcaagc tgcttttgat aattctcgat ccttctttga tccaaataat
    41101 tgctgagagc atctgctaaa aatggatatg taaaaactgc agctccggca agaaacatca
    41161 ctgccataaa taattgtaat aaaagactga tttgggtttg aggtctatta cctattttct
    41221 ttttcatttt cttcaccttc ttatttaaaa aaactgcagc aacctttata aaaccgattg
    41281 ctgcagctta tttttgttgc ttatacttca gacttcattt tagatttacg gtaccagctg
    41341 tacgctccaa tcatcaaact tattccgatt agtaagaatg ccaagagccc gttcccacca
    41401 gtagcaggaa gtgacccgcg tttcatattc ggtactcttt ctggccctgg attttctact
    41461 cctacgatct gaatttcttc attatagctt ccataagaga tgataaattc agtaaaggct
    41521 gcctcacctg ttggaagtac ataaccttct ggcgccatgg tctctttcat ttgataggtt
    41581 ccataatcta acccttgaac ctcaaagtat ccatttccat ctgcgacaaa ttctgttgct
    41641 tgtccgcttg ttgcccactc aattctatct gctcctgatt cataaacagc taaaggcgac
    41701 tcccctttat aaaatattgc gtattcagaa cggtcttcat tccacaattc gaatcttgca
    41761 tctttaagca attcactgct tgatgcatca tatttttcaa actttcttcc acctgttgtg
    41821 actttctctg gcggctctac tccttcttca taatcaaatt catcatttcg tccgatttca
    41881 ataaccgctg tgttgttatg gaaatcatcc gcttctagtt ctgtggaaac cttcaaatta
    41941 tacgtgatcg ttaaatctcc tccacgtgca tctgctaatc tacctaaagt atctactttg
    42001 gctactccat tttcttctgt caaaatcgtc acgacaaacc cgttgcttac tacttctact
    42061 atataatctt gtccttttgt taaaatcgtc tcgccggctc gcacttctat ttcctgatca
    42121 taataagtta gaccaactgt aggcgtatct gtgattttgt aatttttgat aacagcgctt
    42181 ccgttttcaa ggacagaatc gatgaaataa ggaataggtg ctgtgatcgt gtaagaagcc
    42241 gtttttcctc tttctagatc aatataagaa atcgtttctt gttctccagc ttcattaata
    42301 atcgttactt gtctaaggtc gctttcctct acattcatct gtttatctgc ttctctgatt
    42361 tcgtttttcg gatacaaatg cacatctgta ttgtatgtgt ctttccatgt agaaccatcc
    42421 cacacgccat ccaccatatc aggcatcatc actggcatca taacaaccat tggagacgcg
    42481 attctggaaa tatgagctgg cgaataagtt tctaagaaaa gatagacttt atctctagaa
    42541 gaaggtgctt cttccgtcac ttggacggta gagaataccg cttctccagc ttcattcgtt
    42601 gtttgtttgt caatacttgt cagtcgatat tttaaaaacc aactttctgt gtgccgtttt
    42661 tgaatccatt caatcgcttc ggcagaatta agaccgtctt ctcgttccgg tgttaaagga
    42721 ttatctcgaa tcaaatcgta atatacttcc gttacgtcaa acaaatcaaa atcgactcct
    42781 ggaatatttt cttcaccaaa atccgtagaa accaatccgc tattcggtcg ttcttccgga
    42841 acagatgaga aacctttttt gtgtaatgta atcgtcactt cacttggttt ttgtgcgact
    42901 tcttcggctt tgactagttt tccgttcccg aaaatcccta ttcccgcagt aacgagtaac
    42961 agtacactca ttcccgtgac aatcattttt ttattcattt ttttctcccc gttctttttt
    43021 tattaataaa acagcaccta acaataaaag aattcctagt aaagaaatca acgttcttgc
    43081 ttcattcgtt tgcgggaata cggaccattt tcctgattga cctggattgc ttggaccact
    43141 cggctctttc ggtttgtccg ttgtttcttt tacggtctcg ttataaacac gtggtgttgc
    43201 ggattcatag gcagagactg gaactttccc ggattctaat tcagccatct cctgtccgtt
    43261 aactactaca tattgtggtt ggccttttgc atccacccaa aattcaggga tgatgacctc
    43321 gattctctta cttgcttcat ccatctcgta accttccaca ccttttaatt cttcaaaata
    43381 ataggtgcca gaaggcaaga aacgttgtcc tgtcgtaaca aggccctctt tatccgaaat
    43441 gaatttgctt acatttttgt cattcaaagg atcattgtct gctggtttga tccattgatt
    43501 tttcaagtca ttagcaggag ccatatctaa ataatatttc cccccttcta tcatctgata
    43561 tagagcaaaa acagcacctt ctaatggttt tcctttttca gttgttcctc tttgacgtcc
    43621 atacttgaag aagtatggat ctcttagata accgacattt ttaggataga tatgaatctc
    43681 ttgcagttcc tcggttgatt ctgtcgggtg ataaattggc aaaatagcag caattgggat
    43741 agctgtctga tcgatatcaa catccaatcc aacttctgga tcaatcgatt cttcgaaaat
    43801 caaataaact gcatcccgat cttggttttt cttaggtgct ttgatacgtg caatcccgtc
    43861 tcctaatccg ccaaccgtat ctttcccagt tgttaccgaa gtccctattt ggacaagcct
    43921 ttcttctgtg attagctgac ggatattgtt tctgttcgtt tcagcgattt gctggacgaa
    43981 ttctttagga gtcatgtttt cagcagcttt tttttcatga taataatcgg tcatgtcgta
    44041 aatggcaaat gtcgctccat ttagtggcac cgtctgtgaa atgatatctg ctgtttcccc
    44101 tgcttcctca gagatagcca agccatcatt ttcatggtat tcaaattgat cgttataatc
    44161 gatatctcga atcatccgtt tatgcaacac gaattccacg acatcttccc ctgattcttc
    44221 tgccgacatc gcatgtggaa gaaggactgc tgcaagcggt agtaaaacaa gtaattgaag
    44281 catcaaacac aacagctttt tcattacctt gctccctcct ttttagattg tctgacaaac
    44341 aaaccatagg ctgctcctgc aagcgccatg aagaatgcag caagcaggat atagaataat
    44401 cgtccggatc ctcctgtagc aggcaacgga ttttcaggat cgttcccgac actaagctgt
    44461 aatctgattc gatttgtctc caaaagttca tattctaact cttgctgtag atcaggcgtc
    44521 tctgcttctt cgtttggata atacgaaatc tcaactttta gtgtacccgc ttcttttcct
    44581 ggaactaccc gatcattttc tatgtcaggt tcttctcgat aactaatttc taaaataaag
    44641 taacctggaa gttttctata gctgtcaggt gacttcactt ccttgatccg atagacccct
    44701 tccaacaagt ctgaagcatt gaatagggaa gaatcgtttg gatctggtgc caagcctccc
    44761 tcgatgattt catactctcc tgcactattt tgtttctcaa ttgaaaattc tgcgccttca
    44821 agacgtcggc tattcatact gtcaattttc aaaagttcca aatcgattgg cgctagttca
    44881 tcttctaagg ttacttgtag tacaccatcg atgatttcat agccttccgg caagggagca
    44941 gtttcgtctt cgatgaccgt atcttcaatg ataaacttac cttcttcatt cagtgcaaac
    45001 tggaacactt gatcagatag ccgataccca tttggtgcga cagattccga gacctcatat
    45061 tcaccaatag acagatgcag aggttggtcg taatttaaat cgacatactt ttctactcct
    45121 acggcacgag aatagaagta tccgatccca ggcaaacgtt tcgattcttc tggttctaac
    45181 ggattaccag tgtatgctcg atacagcggg aaggaagaat cccccacttt cctgatatcg
    45241 aaacctgcac catctaatgt atggccttca tggtctaatt ttctaactcg gatctcccga
    45301 taatcaaacg tattgtaagc agtgaatgct acccataaac gatcctcttc atctgttgta
    45361 tacgtgagat attgccaatt ttcttcacct gtttgcttga gttggatagt ccctatagca
    45421 ttatcgtaaa gtcgcaagat ccatgtgtca ttttcatcag gttctttgaa accttctggg
    45481 ttctggctct caatgatttt gtattctgca tagttggtag tttcttcact atccttataa
    45541 acaaatgaat ctggctctcc gattggatga ataactttct caccatccac gattacatat
    45601 ttcccgtctt catctactga atagaacgtg agtctccctt tctcttcctc tacttcgttc
    45661 acaccagaaa gccctttcgc tactggatat ccgatttcca gtccgttacc atctgtttca
    45721 taaagttcaa actctgcgcc attgattggc atattactgc cttcaattag tttattgata
    45781 ttcatgtgga ttggcttgaa ttcatttcgc atttccagtt tgacatacaa ctcatcatac
    45841 tctgtgcctt ctatgttagg ctcttgtaca acagaaagct tgtgatattc tccttcataa
    45901 taggaattcg gatctttacc ttccggtccg ccgactctcg aaccagatgt atattcatct
    45961 acaagctcgt agtgacctaa catctcatct tcgttggctg catatttttt gatttggaat
    46021 tgatacgtct catctactaa ctgataacgt ggtggtccag cgatctctct gatccaaaat
    46081 atgtcgctga ctgctccagt ttcatctcct aaaatcggca tcttcgtttc aaagatcgct
    46141 attccgtccg tggtagtttt acttgtttcg attggttcgg cttccccact ctctggattt
    46201 tggtcatata atgcaaattc gactccagcc aacggctcgc cattttgacc cttcttgctg
    46261 acttggaaat tacggccttt atgttcgtaa cgaatggaag aagatgggaa atacatccgt
    46321 ccagtagtga tatcattctc ataatcctcc aggttctgaa tataggccat attgttcact
    46381 gtgcaaaaat ttccgtcttg agctcccgca tcaagtttta cttggtactt gatcctgacc
    46441 atttcccctt cacctaaaga aatcggagaa aatttataag cttggttttc ccgtccgaca
    46501 tacgttgtcg gagtcgccac tacttctggt ggggcttgtc catgacgttc ttcatcccat
    46561 atttctggct cttggtactt catgccgttt tctcctggat ctagatggta aaactgaata
    46621 tctgccgatc tgccagctcc aaatggtgag acattaaaac cagtttcatc ataaagtgtg
    46681 gcttgctgga tcgttctctt gaaggtagaa gagatatcct ccaaggctgt aacaatgtca
    46741 ttcttgttgt tcgcattgta atatcgcggt gttacgccat cttcttctaa atcagcaata
    46801 tttttcaata catttcgtcc aatagcatct agtcgttgtc tcccgctaac gtttccatcg
    46861 attcctaaac caatggagaa gatacttggc gggttctctt gatacttgtt tttcagccaa
    46921 tgatgataag caactgtgtt gatcgcagat gacttttctt gcgaagtagg actgccattc
    46981 gtattgttat tagaagaacc atcaccaacc cagtgagtcg ctttattatc tccttctttt
    47041 acctctccat aacgatagtg tacatttact tcatcttctg gacggttaaa gtcagatgca
    47101 taggtaactg gatgagtaaa ccctgcatta gaagtattcc cagaaaactc ctcaaaattt
    47161 ctgaacaaaa cgtcattatc ttcagcaatc ttatcttcca tcacagtcca gttgctccaa
    47221 gctccattag tgctcgtacg ataacttgac tgaatcggtg cataactgaa ggtcggtgtc
    47281 ccatctccca caacgattag gattttttct ggatttctat tttctccgcc attgtcttta
    47341 tacaatgttt catagccatt tttaagccct agtgtaagcg gagttcctcc gattggtgta
    47401 cgatttaatg ctgtattctc acttcccgtc aaacgattga tatcatttgt caatggaaag
    47461 atgtccgaac tgatttgctc atggttattg atagctgtac tattatggta aaaattcacc
    47521 ataccgattc gaatatccag actcgggtca gagagcagat ctttactcat ttcgtttact
    47581 gcctcaatca acgcagcatt tttagtttga ctattggtcc cagcggttaa ttcactcata
    47641 ctcgctgact tatctagaac aaaaacgata tcgattggac tgatttcctt tttctcgccc
    47701 ccgatgacat ctagatagac attgtaaagg gttgttgcat cttcaggatg tagatcagat
    47761 gctgtgctgc ttggcagaac aggttctacc cattttttga tgtacgcccc gttataatcc
    47821 aagtaactgt tttcaaaatt ccgttcattt ccccaaagct gaacggtttg agctggaacg
    47881 tttctatctt cttcgcctgc agttgatcca ttattagtag catagtcgta atttcgccag
    47941 ttcgctcccc cgtttgtata atcactatca tcgatcaagt tctctccgtc atatggcgag
    48001 cctttgtctc cttgatagcg ttcattgctt tgtgtccaat ttcctaacac ttttgtatag
    48061 tcattcgttg taaacttcat ctattctttc atcaaccacc acttgaagag gtagttaccc
    48121 ttcgttcaca tcggggatct tttctgtttc aaaaatcaat gtgccggttt ctgcttcttt
    48181 tgaataaact tttccgacat accattcttg accatcgatc gtctcgactt ttaggtcttc
    48241 tccatcttca tcataggagg atagacctgt tccacgaacg ttttttacgg taccaatccc
    48301 ggcggctgcc gcatcgattg ctaaacgtat tctaccttca ttggcacttt cctttttttc
    48361 aaaagccaga tgccattcaa gggtttcttc tttttcaata tacttccctt caatttttgc
    48421 atagtcctca tctaagaata cctcatcctc ctttgtttct gttgactcag cagctacatc
    48481 cagggtcgtc atatgataga ctgactggaa atatggtcca aatagcaaac tgacagttac
    48541 taactgcaaa agcttcaatt ttaacccttt cacatcctta tactcctttc aaaaatattt
    48601 gtcttctttc acaacaatca acaaaacaat gcccatctaa ttataattta atttaatttt
    48661 aattttaaat caaatgatat cctttttagt taaaaacacc aattatacaa catttattat
    48721 taaaattaaa ttataaaatt ttataacgtt ctcatttaac aaaacttaag ttattaagac
    48781 aaatgaataa acaactacgc tttcctcgaa acaaaaaaat aaagcacaaa tgcgcattta
    48841 cgcactcatg ctttattcgt acaattaatt cagataacgg cagcgcatag gatgccaata
    48901 acacttccta aaatagctcc tcctaaaatg tcagtaggat aatgtaaaag taaaaaaatc
    48961 ctcgaataag cgatcaaaca agcaaataaa aaggctaata ttcctgcaac tggacttaat
    49021 tcgaacaacg cagctactga taaaaaggct agcgctgtat gtcctgaagg aaaagaagaa
    49081 gtcttcggtt tacttgtgta aaggacaagc cgacgatttt tttcataagg tcttttccgt
    49141 cttgtcgttt ttttgataaa aagcaaacca acaaaaaaat agatcaaact gccgataaga
    49201 atggctagac catattctct agtatcaggt atcaagacta aaacagcagc aaggagcaac
    49261 caaataaaac caccattaga gatattactg ataaatttca aaaaattgat ttttcgacta
    49321 tccgttttcc gttgcttggc gaacttgttg ataatactat catcgatttt agcaatcaaa
    49381 cgcaacatgt tattcctcct ttttaagaac cttttcttgc gtacgatgga taaaaagcag
    49441 gacttgaaaa taaaacaaga aactgaaacc taataaagca aaatagattg gtcctgcaaa
    49501 ccagaatgcg acaagaagga tcaacgtgcc tgccaaatag aaaagcgcgc ttttgaaatc
    49561 attaaaaaac aagaaaaatg cagtaatcca agaagcttct ttttgttcca gttgaagcaa
    49621 gattttgtaa ctaaagagaa gcgcgcttaa tagaagcaaa aacaacgtag tatacatcaa
    49681 tgtatagcca attcccccac cccaatagcg gaaaatctga taatcgatca atagaagaag
    49741 aaaataaaca cttgctaaac tatcttgctt tccataaaga gagaagttct cacgaaactt
    49801 tttccagaat agtgaaccga gctttttctc ttcatttttt ttgtaatgat aaatcatata
    49861 cagaactgtt cgacttgcag ttcctaatgt gaaaacaggc aagacgcaca ggaaccatag
    49921 tagctgtaaa tggataagac gtggaatcca ttcaatgatt tctaagaaat aatcattggc
    49981 ttttttacca atcgatcgat tcatcatcct tttgaacctc ctgtcaaatc catcccttca
    50041 atgaaataac gttgtgcaaa aaagaacagc aaaatcgtcg ggatcaagac aagtgttgct
    50101 cctgccatca gataattcca ttgtgtcgtt gcttggttct gaaaaacttg caagccaatc
    50161 tgtaacgtgt atttttcttg atcttggata tataacagag gacctaagaa atcattccaa
    50221 gctgcgttga aggaattgat cgcaatggta atcaaggcag gtttcgtcaa tggaagcatc
    50281 aaatgactcc aaatatacaa atgattcgct ccgtcgattt cagcagcttc gatcaattca
    50341 ttattgatcg ataagtaaaa ttgacgcatc agaaatatat tgaacgcatt gccgaagaac
    50401 gatggaacga tcaggggcaa ataagtacct acccagccga tcttggagaa taatacatat
    50461 tgagggatca tcgttacaaa ccccgggatc atcatcgtag aaagaaccaa agcaaacatc
    50521 agctttttcc caggaaaatc aagcttcgca aatccataag caataaaaga atttgaaagg
    50581 acattaccga tcactactag cacagtgatg aataatgtat ttcttgcata gcgccaaaaa
    50641 ggaaaggcgg caatcgtatc cagatagttt tcccatacga ttttttctgg gaaaaaggtc
    50701 ggaggataac gaacgatttc ttccattggt ttcaatgaag taaacaccat ccaaagcaat
    50761 ggaatgatca aaatgattcc tattactgtc atgaggacat aacttagtat tttttttgtt
    50821 tgccgattca cactggtctt tttgaaataa tccatcattt gccgtcacct ccagaataat
    50881 agacccactt aggtgcaagc ttcaaattga caaacgtcag aaccaacacg atcagaaaca
    50941 ggatcattga catagccatc gcataaccca tatcaaaagc tacgaacgcc ttgttccaca
    51001 tatgcagatt ataaaaaagc aaagaatttg caggtccgcc tgttccattt ttcgtcatga
    51061 cataagcttc ttgaaaaatt tggaaagaac cgatcgtaga ggtgatcaca tcgtaaaaaa
    51121 taataggagt gattaatggc aaagtaatac ttttgaactt tccccaaacg cctgctccat
    51181 cgatttctgc tgattcatat aaagatctag gaacattttg taatgtagct aagtaaagta
    51241 gcattgctcc tccagaactc catattttca tcaaaatcaa cgcaggtttc gtccattgtg
    51301 gatcaaacag ccaagctggt ccagggatat ggaaccagcc cagaaatgtg ttgatcaatc
    51361 ctgcagatgg agaaagcagc tgcatccata agatgtagac tgctactcct gataagactg
    51421 ccggtaaata gaaagctgta cggaatacac tgattccttt gattttttga ttgagtactg
    51481 tggctaaaaa cacactgaaa atcgtcgtca gcggtacatt gaagatgacg aaataaacgg
    51541 tgttgtataa cgatttccaa aataaatcat cgtgaacgaa cattcttttg aaatttgcta
    51601 gaccaatgaa attcatcttg gatgtcaaat tataatcggt gaaactacca ataactgaaa
    51661 aaagcatagg ccctagcata aataccaaga acccgataat aaaaggcgag ataaataaat
    51721 aggcccatct tgcttctttt ttctttcgga tagataaacg cttcaaattt tcttgcctcc
    51781 tctgtaccta gacagtcaaa aatggattat tgattttgct tgactaagtt ttctactgct
    51841 ttttgtgcat ctgccaatcc ttcttttggt gattttgttc ctaaaagaat ctggtcaatc
    51901 tgttcattca ctaatgtcgt gtaatccgga gcatctaaag gaactggtgt gatcaccgta
    51961 tttttaaagt tttcgtccgc catttgatag atcatttttc ctttatccgt taggttgtca
    52021 ttattcacta aattctcatt ggctgtcttg ctcgccatga tatcaaaact tttttcgccg
    52081 aatttttctt gtacttctgg agaagaaaga tatttgatga attcataaga ggcctcagga
    52141 tcttttgctc cgtatggtac ttccaagacg aatccgccac cccacgacca atggcctgaa
    52201 ccttcttctt tttctgggag ctgcatcacg ccaaaatcaa aatcatccgg tgcattttcc
    52261 atcaaactag agtaataatt gatattttgg gcacgcatgg ctactaatcc ggaaataaat
    52321 ggatcagata caccagaccc aaattcggct tctaatttat tgatcgtatt tttcccataa
    52381 taatcttgcc agtcttggat ccactccaag gcttccactt tatttttagt atcaatcttg
    52441 actttttcat ctttgtcaaa ccaactagtc ccgttatctg cgtttagcgc ccatacatca
    52501 gcccctaaat tccataatgg ataaaaaccg atgcgtgtaa attcttttcc ttctttttta
    52561 tctagtttac gtgctgtttc ttctaattca tcccaagttg tcggtagatc ttgttcactg
    52621 attccagctt ctttaaataa ctttttatta taaaaaatga cttgtgtatc tgtattgaat
    52681 gggatcgcat aaggatcacc ttcatattct actgtatccc aaagctgcgg ataaaaatcc
    52741 ttagaagtgt ctttttctac atatttggag agattagttg cttgctgtgc ttctgctctt
    52801 tgggcaacgg aatttatgtc ctgtacaata acatcgggtg catttccagc tgttattgca
    52861 gataaagatt tagtccagat gtcaccccat ggctgatact tataatttac atggatctcg
    52921 ttttgtgatt gattgaaatc ctcaatgatt tcttcgatag cttcttttcg tgcaccggat
    52981 ccccaaaagg accagaaatc aatatttttt cttccatcac ttgttttttc agaagaattt
    53041 gctgcacttg aactggcatc gcttgcatta cttgatccgc atcctcctaa taaaaacaat
    53101 gctgaacttg ccagcaaccc tgtaaacaat aattttttca tattttacct ccaaatttta
    53161 atgtaaccga tgccggtttt aatataacga tatcattttg ttctgaaaat aacaatttat
    53221 aaggtatgat tctaaaaaaa ttattaatga taccaatact ttatataatt cgcgagcgct
    53281 ttctttgaat tttttaatct ttcgtagcag aatgagaatg tattaaaaat agattaggag
    53341 gaattttgat gtttagacac cagaaagaat tgcagtttga agcaaaacca gatcgtccga
    53401 atccattaat cgcgaaatat ctgcaggagc tgatcggcgg ccaatatggc gagatgagtg
    53461 tagctatgca gtacctgttc caaggctgga gctgccgagg agaagaaaaa tataaagata
    53521 tgctgatgga cattgcaaca gaagaaatcg gccacgtgga aatgttggcg acaatggttg
    53581 ctcgtttatt agagggtgcg cctgttgaag atcaagaagc agcgatgcaa aaagatccaa
    53641 caatcggtgc cattatctct ggaatgaatc cacagcacgc gatcgtagct ggcttaggac
    53701 ctcgtcctgc tgacagcgtg ggcaatccat ggagcggtgc ctatatcatt gcgagtggca
    53761 acttgttagc agactttaga gctaatttaa atgccgaatc acaaggaaga cttcaagtag
    53821 cacgtattta cgaaatgatc gatgatcgtg gcgtaaaaga tatgctgtct gttctccttg
    53881 caagagatag ctatcatcaa aatctatggg aatgtgcagt gaaagaatta gaagaaaaag
    53941 aaggttcaat cttagtccca agtactttcc cgcgtgacaa agaacgaaaa gacattgctt
    54001 atgacttcta taacttctca gagggagacc aaagtagtga aggttcttgg gctagtggca
    54061 aagcactgga tggcgaaggc gaatatcaat ggttgaaaga acctaagatc gaaggcgctg
    54121 caccaaaatt agaaccagta acaccaaaaa tgtatgggac acctccattc aagaaataaa
    54181 tatctacccg tagaaacacc cgttttttgt tccacacgct ttgtgagcaa aactgactaa
    54241 agtcattaat cataaccacc cttcaaaagg gtggttttct ctagagctat aagctcaaat
    54301 caccggccag cgcctaaaga cgctggcttt catattttat gttcaagcca tattgccttt
    54361 gccagttttg cccacctctt aaaaggttta tgtactactc cttagccctt aaaaggatcg
    54421 tcttactctc gtacactcag cttatctaac gcactatcat gtttttcttg ttcttgaatg
    54481 tactttttga tggtcgcttc attttgtcct acttttgtca catagtatcc ttccacccaa
    54541 aagtgtcgat acccaaattt atattttaga tttgcacaat ctcttgatga tctcctgaat
    54601 attggctcga tattgattat aaattatttt tcttctatac tttggtgtga atacaatgtg
    54661 gtatttacac atctactttg tacgggctaa actatttccc tttattgctc cacccgcata
    54721 gcaagtggtt ttgtatttca atcgctcggc gcgctcaatt aggtctaaag acaataaatc
    54781 taaaaacccg ctgcttcact gacagaaaca acgggttttc agaaaaaaat gaaatgaaaa
    54841 agatctctta cggcaatcta ttttattttt ttgatttttt ataaatggaa aatgcttcaa
    54901 gaagtccaag aaataaagcc gtataaaaac aagaacctat gaaatcttta tttattagat
    54961 attcaacaga aatcccgata acactagcca acaatatatt tatcagaagt gtaaaataag
    55021 gatgcttttt atagaataga actagtgttg ttttcataga ctctcctttc ttcatatttc
    55081 caattaatca caaattcacg gcattactag aaaaattaaa ggggcgcaga agtggaaaaa
    55141 tactcttcga ctttccctac aaaccaggcc atcttgtgtt taataactat accaaatcta
    55201 aggtacctct aaatctaaat tccatttgtg gcggtgacct ccaattttta actcttctat
    55261 ctcccatcca gtatacataa ccttgatact tcgaccactt atatatcgaa cacacaaata
    55321 cctatccatt gcaggagtac tacctaactt agttgctact tgcatctaaa taacagctga
    55381 aaagatagga cttactctta gtaaagtatc tgaactatta atttttaaac tatcattttt
    55441 atcctcaact acatgcacat ctgttgcaac ttcactttct gtctcatcca gataaatgat
    55501 taaggaatcg ggaattgcaa tatcttcagc tgacgctgga atagttgagc taaattagtc
    55561 atcatatctt tattataaaa taaccaacag caaaaaatac aatgaaaaac aaacttggaa
    55621 ctaatgtatc attaataaat gttgaaaaat tcagcaactc attactgtat gattttagca
    55681 gcccaaccaa catataccct ataaaagcta ataagatggt taggaatcct ttagaatttt
    55741 tactcattca tagacacttc cttaaataac ttttattata gaaggtattg taaataataa
    55801 tattgacaaa aagtgactca aaataaaaaa aaccttacat tatactggaa tgaactgtat
    55861 tgatagtgta cctaaaagct ctactgacat aagatcgtgt aatcggtaaa gtaattttat
    55921 taattatacg ggatgtaatc aattagagaa taaactaatc ataaaaggta cttttacatt
    55981 cataattgtc gctttgagat tctactttgg ttcactatct gacccaattg cacattttcg
    56041 atcattacaa gtattggtgt cgttagaaca actaaataaa aactagcggt agatttttca
    56101 gaatctatgc taatttctgt atggatgttc cagtgatggc aaatttctct tttcattgtt
    56161 tttcttgtcg catgatatgc ctttttgtgt tattcagtta aactatagaa attctttcct
    56221 agacagatct tgatcccaaa ttttacgttt ttgagcatcg atatagttta aaatgacatt
    56281 actcatatct aaagagttta gattttttag gactaaaact gtcagttgtt ctttttcttc
    56341 tttctgttaa agtattgtcg cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa
    56401 gttttgtgac acaaaaaaac gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat
    56461 gctatatatt ctttagttta agatacggaa attaatgcca tcgaccacac tagtagaatg
    56521 aacgacattt acttggcctt tttttaattt cgttatgttt agcatataaa aatattatag
    56581 agtttactta caatgcttaa aacatatact gtataatctg atcaatttta gccatgtctt
    56641 gcaatggtaa gttttctatt tttttgagtt ttcgttcctt aaaatcaaga gattttaatt
    56701 gtgtaataat tacttgtcct tttatatcta gctcttcagg taatgagtaa cgtgtcggta
    56761 aattctttat agtggaagta attggacata tgaccgaaaa cattgtttta cggttaaatt
    56821 cataacgaga gacgactagt cctggtcgtc ttttttgaat ttcttttcct acggagggat
    56881 caaaatcaat ccatacaata tcaccttttt taggaatata aattctttct tctgacacta
    56941 taaaatttct ctcccttcag gagttaaatc ttcccattcg tctttctcat aatactcggc
    57001 ctcttcccca ccactaaatg gatcttcaat ttttggaact aacgtaattg ttccatcatc
    57061 agaatacaca acgatatatt cttggttttc tgaaggtttc tttccgttat cagaaggtaa
    57121 agttaccact acagaacttc cttgtaatct agattttgta acaagcatta tcatcactcc
    57181 cttaataaaa gtatactata taacactaag taacgcaaaa ttcccctttg taaactatct
    57241 agaaaattgt tttgtttaaa gtatatctta ttggatataa atagaaataa attgtagcca
    57301 gttcattttt tctttaacta aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa
    57361 gctacccaaa tactatagct aaccccccgc taccttcaat tttgcagata aaacgctttg
    57421 ggagaaaatt tcaaagacaa caggccatcc tatcatgccc gattataaac aaaaagctgg
    57481 ctattccttt tgctctgaca aatttcaatt gggaaagttc acgaaactag caggtgaaga
    57541 agtttcaact gttcggatca aagaatgccc gcttcaaata gaaacattgg ttcaacgaat
    57601 ttcaactaga caagactttg ctattgtaga acgtgagatc gtagctattt ttgtagaaga
    57661 agggatttta catgatccaa ctcatatcaa tgtggataaa tggcaacctc ttatctataa
    57721 attcagagaa tatacaactg ccaaccagtc gttaactttg aattttagat tccaagaatt
    57781 caaagagtca taatgataaa catcgttagg tataaataaa aaagactcgc agcacgagta
    57841 aaaaacaaat agaagctata cattagaaag gtcgactgtg accctataga tgcagtatat
    57901 gcagcttatg agcatttctt ctgttctctt tgtttttggg atctgtgctg aagtcttttt
    57961 cgttttttgc cgctctttct ttgaaaaatc gattatgtta taccttctcc attactaatt
    58021 caggcatctg ctgagtaatg atttttcgcg caaaagaaat atctgttacc caaggttcga
    58081 tttgttcttc agtcaagaca agcggcattc ggtcatggat tggtgcgact gtgcggttag
    58141 gttcagtagt cattatgatt gattctgcca ttttttcatc ctgatggcta cgataaaaac
    58201 cgccaatata cactattttt tccttatttg aaaacataaa tttgtctttt tcttcattcc
    58261 actcattggg aaaacacaac gattttgcaa aaatggttga tgaaaggtct ttttttcttc
    58321 tactgtctct gcacgggcat taatcatcaa ttgtcctttt ttaaatccgg taaatcccca
    58381 cttcatgatt tccggagtga ggatgttttc ttcctctttt cttaacgtca caacaagatt
    58441 tgacggaaaa acttctccag ctgctaattc tgctgcctgc ttcggttgtt tcgtctgggc
    58501 ttctcgataa taattctgaa ggagctctga ctctagatca aaaaaataac gaccacacat
    58561 cctaatccct cccaatcttt ttttctatca tacactgcaa caagaagttc gcaccaacaa
    58621 aacgctttca atttttgtag aactaaaaaa gttgtgacaa gtgacaaact ctccagtgaa
    58681 tggtattctc ctgccaactc ctcggtcaca agtcacaata ttcaacaaac atgagaagct
    58741 gctttttgaa attgttcctt gtgactcgga gtgaaacggc aggcttacga cctctgggta
    58801 aacggtgttc aaaagccagt ttctcggtat taagccaaat ttatgcaaaa atgtagaaag
    58861 ctattttcac aaaatttttc ttaatactcg aaactaagcg actttttcac aacctcttcc
    58921 ttaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg aaaaatatga
    58981 gcagctattt ttatttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc
    59041 tccactaaac ggtgttcaat cagctaacct tcggtattag ctcaaaaaac ggcaaaatat
    59101 gaggaactat tttgccgttt gtttctctaa tactcaggtc aaagcgctga tttcacaacc
    59161 tctaatacac ggtgttccag aagtagcttc ttcgaaaaat aagccgaaat ttcacaaaaa
    59221 tttgagaagc aattttcgta aattccttct tatttcttga agctgaccac ttctgtcaca
    59281 acctctaatt attaaagaac cttttgcgaa gttaacaatc tttctttgat caattgaaaa
    59341 ttctgcctaa gtagtgatag atcctgtgtg actttcaaca ataagatact tccctggatt
    59401 tcagcaatca acgctttggc ttgacggtct gcttcttcat cggacagttt ttcttcagaa
    59461 agtgccagga tattttgttt cgtatacttg acccattgat tgactaattc tagtagcaac
    59521 agacggtatt cttcatccac tgtactcaac tcaataatca aattacctac aggacagcca
    59581 tgataagtga tctgtgtctc atgatcagcg aaaatccagt ccaacatttc ttctaatgct
    59641 tcttctggct gttttccagc atttaagatg tcttcgaaca attctgtctg ccatacgtcc
    59701 atatgcgcat ggatcaccgc tagacaaact tctttttttg aagaaaagta ataataaaat
    59761 tgaccttttc ctgtatcaga agctgctaga atatctcgga ttgacgtttc atgatagcct
    59821 tttttataaa taagatcttt ggtcgcttcc aagatctttt cctttgtttt caatgatatt
    59881 ctcctttttc atttctcata gtcctatatt atacagtaaa ttcatcattt tttcttctta
    59941 atcgtttaaa aaagactgtg ccaaattatc tgacacagcc ctcactataa aactgttctc
    60001 atatagctag atgttcattg attcaagaac tgcgaggaca aaagcaattc ctatcttatg
    60061 atagttgctc taatacttcc tctgttgtca tcacttgatc tgcaataaag ccaaagttcg
    60121 tcaacgctgc atccattgct tcttggccag gagcaccaat tgcatctgtc gctaccacaa
    60181 cattgaatcc actctctacc aattcacgca tatgggaatc gctacacaag tttccgttca
    60241 ttccaccaag aattactgtg tcgattccat tttttctcaa ttggagcgcc aaatcattgc
    60301 tttctggtcc aaagatttta tgaggagagc tgatgatcgt attttcatcc aaataaggtt
    60361 tcaattcttc gataaaatcg gctcctgaac cttcttccac tgattcatat tgactttttc
    60421 tagcaaacat ctgctgctca agcatcatat gttctcctgc accgccaaat tgccatttat
    60481 ggtcatgtgg gtaaaaataa tgaggagaaa taaagagttt gtatcctttt tcttttgctt
    60541 gttttaccat ttcaatcata ttttcgatcg tattgtattt ttctaagata tcttttgtca
    60601 aaccaaagcc accgcctgct ggtttcaaga actcgacttg cgggtcagtg agaactactg
    60661 ctgtattttt attattgaac atggtggatt ctccattcgt tatttatttt aatacatcat
    60721 ttagagcttc actcattgtc ggatgagaat agatttgatc tctcaataac gtataaggaa
    60781 gttttccatt catagctagc gaaatcaagt tgatgacttc atgagaatct tccgcataga
    60841 tacttgcccc tagaatcaag tcagtttcag ggtcgactaa aactttgaat acacctttag
    60901 gatcttctaa tacttgtgct ttagggacac cgcttgtcat atacttgaat aatttgtaat
    60961 tgacgccttg tgctttggct tgtttttctg ttaaacctac attggataaa gtcggagtga
    61021 taaatacact gtaaggcaca gctttccggt tattcgttgt tcgtttattc tcgcccttca
    61081 actgatccat aatgattcga taatcatcta gagagatata agtgaactgc aatccgcctt
    61141 tgacgtctcc aatcgcccaa atgttgtctg catctgtacg aaggtattca tccacagcga
    61201 ttgctccgcg atctgttagt ttaacatctg tattttctaa tccaagtgat gctgtacttg
    61261 gttttcttcc agttgcagcc aaaacttttg acgcttggat tgttacttct tggccatctt
    61321 ctgtaaaggt gacggcagct gttgattctt ggtctgctac ttgatctaca gatacaccta
    61381 gatggaattc gattcccgca tttgtcatgt cttctaaaat catttgcgcg atatcttcat
    61441 cttcacgtgg aagaaattca gaatgggcat caagaacgac aactttagat ccgtattcat
    61501 tgaacattga tgcaaattcc aagccaatat atccagcccc gatgatcact aatttttccg
    61561 gtaattgttc ctgatccatc gcttgcgtag aatcaatcaa gtagcgactt gtattcaatc
    61621 ctttgattgg taaaatgatt ggttcagaac cagtattgat gaaaatccgt tcgccttcaa
    61681 caatcacttt ttcaccatta ttcgtcactt cgatttgatg gttagaaaga aaacgtgctg
    61741 taccgtccat cactgtccca gttgcctcat cgctgatcat atgataattt ttggcgcgaa
    61801 gcatgcccgt caatttttct ttccgagcaa cagcctctgt aaagtcgatt cctctttctc
    61861 cattgaaaat caatgattta gaaggaatac agccgatgtt gatacatgtt ccgccataca
    61921 tacgtgttga cttttcaacg actaaaaccg attcaccttt tgaagctaac gccttcgcta
    61981 aagtcttacc gccctttcca aaaccgatca caatattttg atatttttcc atcatttttc
    62041 cctcgcttct tttttaccta ccgattggta caaaaatatg ataaccgata attgtctatt
    62101 ctccaaatca tctgctttat ttgtcaaaaa aaaccagaca aaaagcggtc ctttcacgtt
    62161 tttagtctgg ttcgatttcc tttattcttc taaacaatcg ttacttctac atcgatattt
    62221 cctctagttg ctttggagta agggcagaat tcatgcgcat cttctgcaat tttttgggct
    62281 tcttcttcgc tgatgccatc gatatgcact tctaatacta caccgatctg atagccgcca
    62341 tcatctaaat tataaagaga gacacgtgct tttactgtgg actctgctgt cattcctgct
    62401 tctttgatca tatgttgtac cgccccattg aaacaagaag cataacctgc tgcaaataat
    62461 tgttctggat ttgttccttc tgcatggatt cctggaggag tgattttcat atgcatcgag
    62521 ccatttggtg cctcgacttc tccattgcgc ccgccatggt tgatcattgc tgtttcgtat
    62581 gcttttttca ttgtactgct cctttcgatt gaccatttgc tacttggcta taattatagt
    62641 gtatgacaag taaggcgctt tctacaaaaa ttctgcttat tcgaatacca gaatgccgtc
    62701 ttctactatt tttccaaaaa acaaaaaaat actactcgtg aacaacagcg tcatatttgt
    62761 tccaaaataa atagcaatct tttctacata atcttttata tgattgattt taagatacat
    62821 atataccaga aagttgaccc cataaaccaa tactgttaaa aaaataacca tattcgttac
    62881 cattttttcc tccttttgct ggtctcccta ccagcactcg atttaaccat accacttttt
    62941 ttgccgtcca agcaactagc ctttcaaaaa gactggttta ttctgctgtt aatgattcaa
    63001 gatcagaaaa atgtccgaat aattttgcta attttactaa cgccaacttg ttctttccga
    63061 attcatcatt ttctatctgt aatactagta acggctcatg taagcttaaa cggatcaaaa
    63121 accagccgtt tccgtatggc tcttctagat catatcgaat accttcttca ttttccgggt
    63181 cgaagttcat ccctttttct tcttccaaca gtcgcttcat ttcttctaat atcttgtttc
    63241 cttgttcgcg tggttcatcg ctgaacaatt ttaatcggat ttcttgtact tctacgggct
    63301 gtttcaactc tttgatttgt tcatctaatg tgataccttt tctttttaat tctggcaaaa
    63361 gcatcaggat ctttgcgatg acatatgcac catcatccag aaaatagttt tccttgaatg
    63421 cagcgtgtcc gcttgtttcg atggctagct gtgtatcttt cccaagacgg ttaagttcta
    63481 atgctttatt gattacattt cgatagccgg aaatataacg aacttggatg cctccttttt
    63541 cttcaatgaa tctttgtaga tgagaagaag taggggaatt cgtcacgatt cttgttcctg
    63601 gatgctcttt taatacgatt gtacttaata ctgcgatcaa attatttcga ttgatcactg
    63661 ttccagaagc actgacaact gcagaacgat ccacatctgt atcgaaaatg atcccaagat
    63721 ctgcttcatt tgctaaaaca gcctgcttga tactttccat cgcttcttta ttatcaggat
    63781 ttgggatatg attaggaaat cggccatctg gttccaaaaa ttgggaacct gttgaatccg
    63841 cacctaagct attcaatact ttttcagcaa agaatccacc agcaccattt ccggcatcaa
    63901 caatgatttt ccaaccattt agtggtttgc tttctagtgt tccaatcccc tttttaattt
    63961 ttgtgactaa atcttgcgca taaggtgtca aaaggtctgc tttttctacg cttccagttt
    64021 gttcgctttt tattttttgc tgctgtgata ggataaaagc aatatcttct ttttctgctc
    64081 ctccttctga ggtaaagaat tttattccat tataataata gggaagatgg ctagcagtca
    64141 gcataaccgc agcatcgcac gagaactgtt caaattgagt ggacataaac atagcaggcg
    64201 tagtagctaa ttcgaaatcg atgacatgta tcccttgttc tttcagactt tggatcaacg
    64261 cctctttcag tgctggtccg cttatcctac tgtcatgacc aatcccaatc gtccattttt
    64321 tatttggatc ggttgatttc ttctttttct ttatccagtt tgctagtccc cagccgatct
    64381 tttttaccat gtctgtcgtc aagtttactt catatccttc aactggtaat gcgattcctc
    64441 gaatatccga tccattttgc agcgctttca tatctttcat ataaaagtcc tcctcattta
    64501 ttccctcatt ttttccagct tttctgcaaa tcgctgtgct tcttcttctg agcggcaaat
    64561 aataatgaat gtatctacac cggccatcgt tccgacaact tcagggtaag ccacttcatc
    64621 tagccaattc gttaccacat cggcaccatt tcgttcagtc aatacgataa ccatgaactg
    64681 aacagactgg atacgcaaaa cctcgcgtct aattgctgta cgcaaacgtt cttcatttaa
    64741 agaaacagat ggctggttaa ataatgtata gcgtactatt ttgttttcat tttgactttt
    64801 tactaacttc atttctcgaa tgtctcgaga aatcgttgct tgagtcacat cggcgcctgc
    64861 ttcatgcagc cgcgcaagca gctcttcctg tgtcccaata ggttgttctg taatgatctg
    64921 gcggatcagt gcttgtcgct gtttcttttt catattagac acctctcaat gttgattata
    64981 gcaaaagata agtaatattt cttcatattt tggtattttt tacttttatt ttttgttttc
    65041 attcaggttg ctaacctttt tctattttaa cacgcaaaat cgtcttcatt ttttcaggtg
    65101 ctgattttct tggatcgctg atgtaaatct ctttgtgttc tttagaagct ctttcatagc
    65161 cttcttttgc gatgaatgct tctaatttct caaacgttgc tggttcttcg gcatagggcc
    65221 cgacgtgtaa gatttgggca caaagacctt cttccatctt tttgaatact acttgttctt
    65281 tcaagtcttc cggaagtttg ctagaacgct gaatggcttc ttgtgctatc gcttctgtaa
    65341 caaagtcagg ctgtcggatc atcaattgat aagaaaaatg ttcttttttc atcactggtt
    65401 catgcaaata cttttcttgc agtccccatt gtccttccag tggatagaca gtatacatct
    65461 gataatcagg aatcagccaa ttttttttag gcgacatgcg tattgcatag ctgactgcat
    65521 atagacaggc tactcttcgt ttaaagtctt cctgattcgg gtcgccgatc cctctgatgc
    65581 taaagaatga ttttttagga acctctagta tttgcgggct ttttttcata ctatagctct
    65641 tgtctttacg ccattcaatt ttttccattt ttcttcctcc gcgaaattcc atttagttat
    65701 ttattatcat acctcttttt gagtgacttg gctaatcgtg ttgacactat ttttcagttt
    65761 gtgctagaat aagtgaagta aataaatcgt acagataaca cgtttcggcg tgtcgagaga
    65821 gaggcggttt ctatttttat aatagaaatc actctctttt tttacgaaat tttttagagg
    65881 tgatgtaaat gacaaaacaa aaacagctgc ttttagtacc tgcagtaatt gcaacaggga
    65941 tgatgtcttt tgcgggcgta ttgatcgaga cggccatgaa tgtaactttc ccaactctta
    66001 tcagacagtt tgatttaacg actgcacaag tccaatgggt aacaacgatt tatcttttga
    66061 tgatttcgat cattgttccg ctgtctactt atttgaatcg caattttagt ctcaaaaaac
    66121 tctttttagc ttcaaatctg cttttcttgg caggtataat gatcgatttc ttctctccta
    66181 ccttcatggt cctattgttt ggtcgattgc tccaaggtgc agcgacaggt atcgctcttc
    66241 cgttgatgtt ccatattatc ttgacatttg cccccctcaa tcgacgaggc gcgatgatgg
    66301 gtgtcggtac tttgacaacg gccattgctc cagcaattgg ccccacttat ggaggcatta
    66361 tgacttcaca ttttacatgg aatcatatct tcctgtttct tgtgcccgtt ttgtttcttt
    66421 ctttgattat cggctggttt gctattcccg agatggcagt acaaaaaagt ggttatttgg
    66481 attggataag cgttttagga atttgtcttt tgtttagtgg aagtctaaca tttttgagta
    66541 cgttgggaac agtttccagc tggattgctt taatcatcgg cggtattggc tggttccttt
    66601 tttactatcg aagtaaaaaa gtggagcatc cactgatccg actgtctatt ctttcaaata
    66661 aaacattccg cttgtttttg attggcttct tagtttatca gtttttatta cttggtgtat
    66721 cttttgtctt gccgaatttc cttcagatcg ttcaaggaag tagtcctttt gtcgctggat
    66781 tagcgatgct tcccggcgca gcggttggtg ctttgctttc tcctttttcc gggaaaatgc
    66841 tggatcaata tggtccgaag aagccaattt ttgctgggct gattctttct ttgattggtt
    66901 ggctagcatt attcctactc ataggacacg cttcagtggg tgtattgatt gcttgtcatg
    66961 tgttttatat gatcggtatc ggattatctt acagcaatat gatgaccacc ggaatgaatg
    67021 cactgaatga agaactacaa ggagacggga acgcaatgtt caataccttg cagcagtttt
    67081 ctggcgctgt ggctacttca ttagtagcgg tcattatcaa ttacgtccag catcatactt
    67141 cccataacta tgaagtgtct actacattag gatcaaaagc agcattaggc gtcttgttgc
    67201 tgttgcttct cgtaagcttt gctcgattcg cctattatct gttctttgct aaaaaagcgt
    67261 agattccata tacggcaggt gttgcatctg ccgttttttt gtgtgaaaat ggttgtttgt
    67321 aaaaggaggc ttttttatgg aaaaaattgc cattatcggt ggcgggatca ttggtatgac
    67381 cctagccagt tacttagata catcaaaatt caatgttgct ttatttgatg aagggacagg
    67441 acaggcaact aaagctagcg ctgggattat ctccccttgg ttgtcgaaac gcagaaacaa
    67501 acaatggtat cgtctggcta aagacggcgc tgcttttttc cctaaactta taaaagattt
    67561 ccaacttgat caaacgattt acgcacaatc agggacactt ttgcttcgac ctgaaaaaga
    67621 tttagctgaa ttggctgttc ttgccgagaa acgaaaagaa gaagcgccag aaattggaaa
    67681 catcgaatgg ctttcacctg aacagacatc tcaagcactt ccgttattga aaccagcagt
    67741 ttcactgcgt atcagtggtg gtggtcgtct ggatggaaaa gcatatttag aacatcttgg
    67801 tcagcgttta gcacaaaaac aaatggagca gatccaggca aaagtcactt tgcataagaa
    67861 gagcgattct tggctcatca agggaccgtt tggagaatac acagctgatc gtgtaatttt
    67921 gacacctggc ccggcactta agcctttatt acaagaatta ggctatgctg cagatatacg
    67981 tccgcaaaaa gggcagctct tagcatttca gacatcttat aagatgagtc aagactggcc
    68041 tgttgctatg cttgacggag aagctgattt cattcctttc atggatggaa agatcctttt
    68101 aggtgctacc catgaaaacg atcaaggctg ggatttggct cctactagcg aagcttataa
    68161 gggattgact aagagtacag aacagttctt gactgatcca gatcagataa aaaactggcc
    68221 atacgagttc cgtgtaggta cccgtgctta tacgtcagat ttttccccat ttttcggcgt
    68281 actgccagat gatccaagct tactggctgc tagcggtcta ggctcttctg gcttgaccac
    68341 aggtccttat atcggctatc tattagccaa cttcttaaat actggtcatt ggcctacgga
    68401 agattatcaa aaggacatct ccacctatat tacgaaaaat ccatcataga aaaacagctt
    68461 tttcaagtaa ggatcccgag cgatattgcg catggattac ttcttgaaaa agctgttatt
    68521 ttagttcaat ttctgaatca aattctccaa actttctttt gcttcatctg gcaagagatc
    68581 ttttcctatc tgagcttcaa tgaatcgtaa acgaatatca agtcgttgtt tcaccagatt
    68641 tttataggac gtatcctcaa aagaaacagg aaaatctggt ataggtaaat agtggatgtc
    68701 ttcaaatgga ccaaacgact tgaattctgc cgtttgttgc acgattcttt caacgattga
    68761 caatgtcgtt tcaggtttga tttttttatc atcgaaatat ccagtattca ggacatagca
    68821 ggctgtttgc tgtttcaaaa acaactctcg aaaagcttga tagtcttccc taagaggata
    68881 gacacggaaa ggattagcaa atggttcaat gactagctca tctagctgtc tttttgtagt
    68941 gatattttcc gcgtctgatc gttttgttgc taatgttgca ccaaaagacg ctgctaaaac
    69001 tgggtcattg atcttgataa ttggcggaag cgaatcatct ttcatgatcc aaaaaacagc
    69061 atcgatcttt tcgctaagat gatcgactcg gtcgggtgtc gcataacgtg atttgactgt
    69121 ccgcccattt ccgtttcgta tatctcctgt tactaggact ttttctcctt tacttgtaca
    69181 tgtcacgccc acattctgac aagtaaggaa agaagaaatg gccggatcat cagacggata
    69241 gtcttgtgtt ttatcaaagt aagaaggttc caaggcagta gcaaaaccat tttttcgaga
    69301 aataacgaaa gcatcgtcat gcaagatcga aacagagtga ccttccgtat gttttgctaa
    69361 ggtaatcgtt gattttccag aaccggacaa cccaaataca gccatcgtat aggtctggtc
    69421 attactagca tattgtttca tcccaccgtg gcaggcaata aagccattgc gatttcccaa
    69481 tgcccaagca agcgtcaaag tcgctttttt taattctcca aagtaacgta atcctagcac
    69541 agccgctgta ttatggagag catcaaacaa aatgagtcca tttggaaatg tttcatgtgt
    69601 ccattcggga tcacaaaaga tataaagatc tccctcatca aaggaaacag acttttgata
    69661 agtctctaag atcttcgaat tcgctggctg aaaattcagc aaataagaat acaaattgtt
    69721 ctcaaatcct tctggaatca gcaaatgact ttgcacagaa aattcttcag ataggccaac
    69781 gattactttt gtatggtaaa actggcgctt gcgactttga tacacagctt ctcttaaaat
    69841 tttctcgtat ttgctttgtt ccttgtctaa gtcctcaaag atccgccgag cacttgctgt
    69901 tcttcccaca atgcttccat cattgaatac tagtgtccta acatcagctg gtaaatctag
    69961 ttcttcagca tgtgagattg ttaaatctgt gatgatcgtt cctggactcc cttttgctag
    70021 ttgataagct gtcttcctat caaaaacttc atgaacatta ttaccgtaaa atgtcgtttc
    70081 tacaatcgat cgaatactgg ataacagtgg atttccactt gtgatttcgt ttaattcgag
    70141 actctctttt gtactcatgg ctcctcctca ttccctaaac aaaaaaacgt tttctttatt
    70201 atacattatt cgagttttta tttgtactgc tgcgctgtgg gaagcaaacg agttattttt
    70261 cacacaaaaa aaccgagaac ttgaataaac aagtttctcg gtttcatcat tttcctttta
    70321 tcggcttagt accagccgtt tgctaaccag aatgttttag cagcatccca tgaaccataa
    70381 cgagatgtta catattgttc tgctacacgt tcttgattgg cagctgaata gtcgccgttt
    70441 aagtatgaag catctaattg ataacggccg atgtaacgtc cgttagtagc tgtgtatgaa
    70501 ccgcctgatt ctttttgtgc gatccattct tttgcagagc ttgaagttgg cgctgttgca
    70561 gcagctgggg cagcaggagc tacttcaact gtttcaacag gtgcaacgta tgtatgttct
    70621 tgcgttgctg tttcagttgt agatgctgta ttttctgttg ttttgttttc tgttgttgct
    70681 gaagaatcat ttgaagttgg gattgttaat tgttcaccaa cataaatgcg gttgatgttt
    70741 gcgatcgaat ttttttcagc aattgcatcg atcattgagt tgtctcctgc aaatttttgt
    70801 gagatcttag ataatgaatc acctgatttt actgtataaa cttcatcagc gtgagcattt
    70861 gtagttccta caaacattgc agtagcacca gcagcaaaag ttgtacctaa aacaattttc
    70921 ttaaatgaat tcatattaaa ctcctttttt tctccgtttt ttattctttc gacgctatta
    70981 actttatcat ttagaaatat ttcataggta aaagaaacat gacatttaat gacaaaataa
    71041 cgaattattt aatatttgta acatttaaac aaatattttt ttgatacaaa accataaaag
    71101 ccttgttgta taagcaaagt aatcgttttt ctatgttttt ttatttttga atgaaaaacg
    71161 cagattctgt aacattcact gcaataatcc ataaaaaaaa gcaaaaaaat ttttgatttt
    71221 tatcaaattc tcttaaaaaa atgtaaaaaa tacaaaaaaa ccagtaattg ttacaacaat
    71281 tactggacaa aaactttgaa taatgttaac tattttttta ttttaacttt ctccgcaata
    71341 atttctgggc atgttccaat tcgtttataa cgacttcttc tgtttcttta gctaatattt
    71401 catctaatac atcaagccat ttttccggtt cttttgttcc tagacgtcca atagcccaag
    71461 ctgctgttcc tctgatgaca gggcggacat ctgttaaaca ttctgaaatc tcaggcaatg
    71521 ccgttcgatc acctagatta gctaaagcaa tcaatgcgtt tctctgcaaa ggtttcttcc
    71581 cacgccatga accagctaaa tgcccaaatt gctgtttgaa gtctttatta gacatcgaaa
    71641 gcattggctt taattttgga tatatttcgt ctacttttgg ttccatctct tcatgaaaat
    71701 gaaaatcttt tccttgattg taagggcaga ctaactggca gatatcacat ccataaatga
    71761 catttcgcat ttttttacga tattcttccg gcatcatccc ttttgtctga gtttgataag
    71821 acaaacatcg ctgggcattc attcttccgt caccaagcaa tgcttttgtc ggacaagcag
    71881 tcacgcagcg catacagtca ccgcaaccaa attctcctgg tttatcaggc tcaaatacaa
    71941 tattagtaac gatctcacca agatagacaa atgaaccgaa ctcttcagtg atcaacaatc
    72001 cgtttcgtcc aataaatcct aaaccagctc gctgtgctac agcgacatcg atcagttctc
    72061 cagtatctac ttgcggagct agacgccatt cctcttcttt ttgccatttt tctgctcttg
    72121 tttggatgaa ttcgatcaat cggttcaaac ggtctctgag tatatcatgg taatcgatcc
    72181 cccaagaagc acgagcaaac tgcccgcgtt tttcatccct aggcacttct tcatggatcc
    72241 tagtaggata cgcaagtgca atggaaatga tcgatttcgg ctgatcaaat gtcatttctg
    72301 gataaagacg ctcatcgata tttggatgtt caaagccaga agtatggcca gctgcttttt
    72361 gttcttccaa cgattctttt aatgaatcaa aaggttccgc cgtggtgaac ccgattttgt
    72421 caattcctaa tcgtttgctt tcttgtatga tttcttcttt taatgtcatg gtcttcctcg
    72481 cttgctgtta acggctgtat aacccataat atagtttttc ttttttcagc tggacaaact
    72541 ggatctgctg atcggcaatc ttcttttctt ccatccattt ttttcttgca gcaaatactt
    72601 cccaataatt tgttgaaatt aattttcttt tgttatctaa tgcattaaaa aaattcaatg
    72661 aaactggttt tgtacttaac agttcatgga gccttacctc ttcccatggc gaaaactcag
    72721 acagatcgcg ggaatacaat acttcttcat agagattttt ttgctgtgtg tacgtgaatg
    72781 tttgcgggat tttcccaggc ctagcaattt ctactagacg attataaaac atattcatta
    72841 atttgctgtt ggcaataaat tgacttttat aataggccga ctggatcttt ttgattactc
    72901 cttctgcttt gatgactgaa aataatgcag gccatgcttt gacggttatt tcgtcgtttt
    72961 gtttaactaa tacgccaggt gtgaagccga ctggagaaag gaacacaaaa taaccgatac
    73021 cggtattttc atctaaaggc tgaaattcat caaacaacca tttgcctatg tacagctctt
    73081 catctggttc tgttgtctca ttttgatttg ctatgaataa tttagctaat tctgcttcaa
    73141 gaaattgaag gtcttgatcc ttgtcggtat tttcctgctg gctgatcaat cgaaagactt
    73201 cttctttaat cgtatattta tctttacgtg taaaattcat agccacacct tccttcctta
    73261 ctctaactat aacggaattt cttcaaaaaa ggtatctgta cgacgaaaaa cagcataatt
    73321 ttttttcata tctcttataa aaaatgcaag gtctgctcct caagctagac cttgcacttt
    73381 tcagctttct tttgtttgtg acaaaccttc atggatcgtt tcaatattcc atttcatcat
    73441 ctgatagtaa gaatctcctt gttctccttc ttttgctatg gaatcagtga acagtttatc
    73501 atagattttc aaacccgttt cttttgctac ccgttccatg cttcttgagt ctacactggt
    73561 ttccacgaat aaaaccggta cttcttttgc tcttatctga tcaatgatcg ctttcatttg
    73621 atcaggcgta ccttgacttt ctgtattgat ctcccatata taagctgctg gcaaatcata
    73681 tgctcgtgaa aaatacttga atgccccttc acttgttact aataattttt tgttctcttc
    73741 gatagaagca aaactttcct tcgcttgtgt atctaattct tttagttttt ccacatatgc
    73801 ttctgcattt tttttataga gtgtcgcatt ttctgcatct ttttcagaga atatacgtgc
    73861 gatttcctcc acatatttta ttccgttaga taggtctagc caagcatggg gatctgcttt
    73921 tgtatgttct tcaccgctag ttaaataaag aggttctaca tttttgctaa ctgcaaaata
    73981 atcttttcct tcttcttttt tagccgtttc catcaagtta tcgaaccagc tgttacctgt
    74041 ttcaagattc aaaccgttgt ataaaataac atctgcatcg cttgcctttt tgatgtcttc
    74101 tggtagtact tcatattcat gcggatctgt tccgactggt acgatactgt ggatatctat
    74161 ttgatctgtt ccgacctctt ttgccatgtc cgccaagatc gaattggtag ccacgactga
    74221 caacttttct ttacttcctt catccgcttg gtcagaagcc tgctttccgc aaccggctaa
    74281 taccaagaaa ctaactgcca agattaaaaa gagtgatttt tttgttttca tctatctgct
    74341 tcctttctga aataaaattc cttttgttgg agaaaataaa aaagcaagga taaaaaatgc
    74401 ggtacatgct aacacgatcg tagctcctga tggccaattg taactataac tgaaaaacac
    74461 accgacaact gcacttagca taccgattcc tgcagctgta atgatcattt tcagtaaatg
    74521 gttcgttagc aagtaagccg tggcggctgg tgtgatcaac atggcaatca ccaagattgt
    74581 tcctactgtc tgtaaactga ctacagccac taatgtcaaa aagaacatca aaagataatg
    74641 gatcagcgat gtgttcagcc cataagcttt tgccattgtc ggatcgaatg atgtgatctt
    74701 caattcttta taaaagaaaa agacaaatat caagacgatt ccactaacga gtgctgtcag
    74761 caacaaatcg ctttccctaa cagctaagac attcccaaat aaaatatgat acaaatctgt
    74821 cgcactctgg gcatatgaaa tcaagataat ccctaatgca aaaaaggagc taaagacaat
    74881 tccaatcgct gtatcatttt tcaatcggct ccgctgagtc acgaaaccaa tcactgctgc
    74941 tgttagcatc ccaaaagcag tggctccaaa gatgtaacta aaaccaaaca tataagaaat
    75001 ggctacacct ggaagaactg cgtgagagat agcgtctccc atcaaagaca tccctcgtaa
    75061 aataataaaa gaaccgatga ctccagaagc aagtcctaca agcatggaag tgaccaaagc
    75121 gtattgcagg aattgataat tcattaatcc atcaataaag gattggatca ttttttctct
    75181 cctcctttta ctaaatgtct gatgatctca ccataggcca attgaaggtt cttcgatgta
    75241 aagacttctt gtactggacc ggaagcgatc agctgtttat ttaaaagaat aacctcatcg
    75301 aaatattctt ctactttatg aagatcatga tggacgatca aaatcgtttt tcctgaattc
    75361 ttcaattcct gcaagatgtc aaagatcttt cgttcactta acgcatcaat ccctacgaat
    75421 ggttcatcta aaaagatcca ttctgctcct tgggctagag ctcttgcaat aaaaactctc
    75481 tgaagctgtc cacccgatag ttcgctgatc tgtcttttgg catattcttc catccctact
    75541 tttttcaaag cttgtcttgc acgttctttt tcttttttcc caggtctttg tccaattcgt
    75601 aaagatggat atgttcctaa aagtacaacg cctaatacat caattggaaa ggaaagatcc
    75661 aattcacttc gctgttccac gtaggctatt tttttacgga ctgagtttac cgactgtcca
    75721 gaaaaggtga ctttaccagt agtagctggt atcaactcta gcaaagattt cataaatgtt
    75781 gattttcctg caccgtttgg tccgataata ccggtaattt tttgtggatt tatcgtcaag
    75841 ttgatagttt tcaaaacagt tttcccttga taagcggctg aaaggtcttg aattacaatg
    75901 gccgtacgtt ccaaatctta cactcctttt taggtttacc taacttttta tttaaatata
    75961 gtttaactaa aatggaaagc attttcaagt agaatgatga aaaagttttt ttcgaatttt
    76021 cctcgcattt tatgaaaatt ttctgtagaa tcacatcaag agttcaataa ggctaaccta
    76081 ataatgaaaa acatgtgttg aaacgtttga ttattttttc ttgttgactc aacaacgaaa
    76141 ggagtttttg tatggaagaa gaaaagttaa ctcgaagtct tagtgcccgt catatccaaa
    76201 tgatcgcact aggtggaacg atcggtgtcg gtctgtttat gggtgcctcc tcaaccatac
    76261 gttggacagg gccctcagtg atgggagcct atgcgattgc aggattcttt ttgtatttga
    76321 ttatgcgtgc tttaggcgaa atgctttacg ttgatccttc gactggttct tttgcaaatt
    76381 acgcgagcga gtacatccat cctgtggctg gctacttgac cgcttggagt aatatttttc
    76441 aatatattgt cgtaggaata agtgaagtga ttgctgtagg atcttatatg aattattggt
    76501 ggcctgattt gccggcaatt attcccggaa tcattgtcgt cttgtttctt atgctggcaa
    76561 atcttatttc tgtcaaggcg tttggcgaat tagaattttg gttttcgatc atcaaagtca
    76621 taacgatcat tttgatgatc attgcaggtc ttggggtaat cttatttgga tttggtaatc
    76681 atggtcaggc agtagggatt tcaaatcttt ggaaaaatgg tggattcttc actggaggcg
    76741 tcaaaggatt tttctttgca ttatcgatcg ttgttgcttc ctatcaagga atcgaactga
    76801 tcggaatgac tgctggtgaa gcagagaatc ctaaaaagac gatcattgaa gctgtccagt
    76861 ccactatcgg tcgaatcttg attttttata ttggtgctat ttttatcatt gtgagtatct
    76921 atccgtggaa tcaattgagt gagattggtt caccttttgt acaaactttt tctaaagtcg
    76981 gcattacatt tgctgcagga ctgattaatt ttgtcgtgat tacagcggca ttatcaggtt
    77041 gcaattcagg gattttcagc gcaagtcgta tggtctatac acttgccata aatggaaaga
    77101 tgtctaaaaa atttctgaaa ctatctcgtc acggtgcgcc tttttatcct gtcgtagcaa
    77161 tctcaggtgg aatcttaatt ggtctgatct taaattatct tctaccaatg ttcatcaacc
    77221 agtcagaaaa tattttcgtt ttcgtataca gctcaagtat tttgcctggt atggttcctt
    77281 gggtagtgat tttgatcagc gagattcgct tcaaaaagaa gcacgcagat aaaatgcatg
    77341 atcatccttt taaaatgcca ctatctcctt atacgaatta tgtgacactt gcttttttag
    77401 ctatcgtatt gattttcatg tttatcaatc ctgaaacgag aatctcattg attattggac
    77461 tcgttttctt gctttacatg acgatccatt actttgtacg cgaaaaaaga accggaaaat
    77521 aaaaaaagaa cgaagcttca ccttagtgga agcttcgttc ttttttattg cttttatcaa
    77581 ttcaatttta gcgtctcacc gggagtcagg aaataattct ccatgctcat cccattcagc
    77641 gacaagatcg tttctactgg tacgccagtt cgttcggcta tttgatttgg accttctcct
    77701 tccaaaacta cggttgtcgc agcctgtgaa gtcgcgctgt tggtattagt ttcagaggaa
    77761 tctgttgtgt cttgtgttgt tcgagcttgc atttcagaag cttctaccga ctctgctgtc
    77821 tcagaatcag aagatgttgt gtcttgtgtg cttgttgact ctgcttgaag agaggcgcta
    77881 gtctgcaaat aaatatcgga aatcttagcg acatgattcg tataattagc cgataattga
    77941 ttgatcaaag tatctaagtc tacaccgtct ttattttctg ctgcctgata cgctgcacgt
    78001 aattttctga tcccttcgtc ggagattgct tgaagctcac gtgctttttg gttagcaact
    78061 gctgataaac cagctattcc ctcttgattt ccctgaattt ctgtctggta ttcttcaatc
    78121 aatgcaggcg tcttttcttc gatctttttc gaataatcat ttacgattgc ttgaagttgc
    78181 tctggcaaac catttgctgt tttttcttca gaagtttgtg tctcttttgt tttagttgat
    78241 gactcacttg tttgtttcgt ctctgttttc tttgtcgttg tttccgttat ggtcgtactt
    78301 ttcgcttctg acgaattttt tccatgaaaa tatagacccg caactcctcc tgctatgatc
    78361 aaaaacacgg caactgctgc cccaatcatg atcatccgct tacgagctgc ctgtttttgc
    78421 tgtcttcttc gggtcatccg aacattttct ccccactcat tttcatcata catttttttc
    78481 accaccaatt tttatgtata atagcgttat caaacgcttc atattcttat tgtagcaaat
    78541 aattgtcgct gtgcacattt ttatctttgt tatttataag aaaatttcac cagttgagat
    78601 gattccaaga ttgtccgtcg atttctcctt gcagctgcat tgttcgttcg tctatctcag
    78661 ccatcagttt ctttatttca tataagagcg cacggtcttg atattctgat ttttcgctta
    78721 attcatctaa ttgttggatc agccaatcat ttgtcataat gaagttcctt tcatttcttg
    78781 cagtgtaaag gtcaagtctt cgatctgctc ttttgcctca gtcagtgctt ctacgatata
    78841 tgcttgtttt tcagattctt cttcctgcat tttctgattt tcctgtactc tttgaataaa
    78901 ccagtcaatc cgctgagtca gcgatggttt gccttccaat gagagatact gctgataagc
    78961 aattagcttc tcccaacgtt tttcctggga taaatacata aattgtgcta aaacgaatgg
    79021 cggaagatag gtcatatgga atttatttgc gattcgctga tacggcctca aaaattcgga
    79081 aatcgtatat tcttcttttc ctccagcttg gtattctttt tccgccacac ctgttgtcaa
    79141 tacgattcct agttctttcc cttttaatac atgtgctgct cgttccaaga cattatcttg
    79201 ccaaattttt aaatgagcag gagaactata ccagtaaaac ggaaactgga aaatgatccg
    79261 atcatgctgg gccaagagct gtagttcagt ctctatatct atttttccgt ctggataact
    79321 tgattccaaa tgatgccaag tagctggtaa accagcagaa gcttctttga aaaattgctg
    79381 atttaaagat tcttcgatcg ttggatggct aatgatgata agtgtacgca tcccttttcc
    79441 tcctttttag tcttcgcttt acagtgtagc ataaccgcca caagtttctt ttgccgatgc
    79501 ttgtcatttt aaccagacta atcaggttgt ccaagaaact gcggtttgtt tttccaactg
    79561 ttttttcaag gtatccaaag caatattctt aaaattttcg tttttcatac gtttacgata
    79621 gttcgtagcc gtttctccgg tactcttttt gaacattcgg ctaaatacga ctagactatt
    79681 gaaccctact tgataggcaa tactttccac ggattcatcc gtcagagaaa gaagaaacgc
    79741 ccctcgattg atccgtaccc cgatcaaata ttccttgata ctggtaccca tatgattttt
    79801 gaatactcgc gacaaatggc tccgattgac cgctaaatgc tgggcgattt cctcaacaga
    79861 caatttttca gcataatgtg cctcgatgta tttgactgtt tcaacagcta aagaggaatg
    79921 aaccttttgt acaccaccgc tgacctttcc gccatctttt aaaaggactg ataaaaaacg
    79981 gtaggttaat gctgttaact gtaattcatt ttccaaggtt tcttccgtat ctttcatgca
    80041 ttctaaaata atgtcgatat atttttgtat gtcagaagag accatcgtgt attggtcttc
    80101 tctgaaaagc gactgccgaa tgatttcttc tgcagcactc ccaccaaatg aaagccagca
    80161 atacatccac ggatcttctc catctgataa gtaaaacgtc gagtctcctg gacgaatcaa
    80221 gaacagatca ccttttttca attggaattg ttgatttttc acatgataag atcctttgcc
    80281 ttccatcacg acatgcagga tgtaatcatt gcgaatagca ggaccaaaag aatgaaacgg
    80341 catcgtttta gagaaaccac aaaaatcaaa atacaattct ttttctactt gttgatgttc
    80401 cttttttaaa aaaatcgatt gctccacgtc tatccctcct tactccttta gtataatgca
    80461 acaaaaagtt aaataaaagt cacagaaata tattaaaaag gaagcgattt cttgttaagt
    80521 ttaagtcatt aaaagatctt tgttattcgt tgtaaccggt ttacttagta ttatatattg
    80581 aacaggagag gaatacagat tatgaaaagc aaaatgatcc aacgtgtgtc ctacgcttta
    80641 ggcgcttttg gacacgacac attctatgtt acattaagca cttattttat ggtattcgtg
    80701 acaagccaga tgttcgcagg aacagataag gcaacgaatg caaaaatgat tgctacagtt
    80761 acaagcttag ttgtaggtat ccgcttagtt gaaattattt ttgatccttt gattggtggc
    80821 atcatcgata atactcgtac aaaatacggt aaattcaaac catggttagt tatcggcggc
    80881 gttgttagtt ccgtactctt ggtagcaatc tttaccaatt tctttggctt agctactcat
    80941 aatacgactt tatttatcat attatttgca atcgttttca tcttattgga tagtttttat
    81001 tcatttaagg atatcgcttt ttggtcaatg attccagctt tgagtacgga aacaaaggaa
    81061 cgtgaaaaat ttgctacgtt tgctcgtttc ggctcttctc taggtgcaaa tggtactact
    81121 ctagtcgttg tccctatcgt tactttcttt acctatcttg ttactcataa acatattgaa
    81181 ggcgcttcag gctggttctg gttcggtgtg attgctgctg ttatttcagg cggtactgcg
    81241 attatcactg ccttgggcac aaaagaagtc gatactgcga tccgtcagca aaatgaaaaa
    81301 gctgggatca aagatgtgtt caaagcagtt gctcaaaatg atcagttgat gtggcttgcc
    81361 cttgcttata tcgcttatgc gattgccaat gtagcaacaa ctgccgtatt attctacttc
    81421 ttcaaatatg tacttggcca accaactgaa ttttggatcg ttggtctagt tgctgcctta
    81481 cttggtttag tagctgttcc actattccca atgcttacac gcgtcatctc tcgtcgctac
    81541 gtttaccttg gagggatcgc aatgatgatt tcttcttact ttttctttac gatcgcaggt
    81601 tcaagtttgc caatcgttat catcgggcta gtattgttct acttccctca acaattgatt
    81661 ttcttatccg ctttgatgac gatcacagac tctgttgaat atggtcaatg gaaaaatggt
    81721 atccgtaacg aagctgttac tctatcaatt cgccctttac tagataaaat cgctggtgct
    81781 ttgtctaacg ggatcgtagg gtttgtcgct atcgcttctg ggatgactgg taatgctact
    81841 gctgctgata tcactgctca tggcgtaacg actttcaaag cttatgcatt ctatgctcct
    81901 gctgctttga tgattttctc cgctattatt tttgcttgga agattacatt gacagagaaa
    81961 aaacatgcac aaatcgttga gaaattggaa aacaaattgg ctccagctga tacaatggaa
    82021 gatgaacttc acgatgcagt agttccttcc cattaagaaa ggatcttgaa aatgaagatt
    82081 acagaaaaag attttggcca aggttatcac ttgataacct tggagaacaa aaacaagcta
    82141 gcactttcta tctctgattt aggtgctaga atcgtcagtt taaaatcaaa tgatcgagaa
    82201 ttagttttgg gatttgacac cgctgaagaa tatatcgaaa aagatccgta tatcggtgct
    82261 tctatcggtc gcaccgcagg gagaatcgaa aatggccgct tttctctcaa tggaaaaact
    82321 taccaattag ccacagatcc aaaaactgga cataatctgc atggtggtgc tcctggattt
    82381 gaattaaaaa aatggtctta tgtcattttg aatggcgaaa atgaagcttc tgtcattttt
    82441 actactacaa gtcccgacgg agaacatggt tttccaggta caatggatgt ggaaatccgc
    82501 tatactttga caaaagataa tatctggcga gtgacctctc gcggcaccag tgaccaagat
    82561 actttattca atccgacaaa tcatgtttac ttcaacttga cgggagatgc ttctcagtca
    82621 atcgatcaac atgagctttg gctcaatagc gaagcttatg ctcctttgcg aacagatagt
    82681 attcctatag gggtaaaaga aaatgctgca ggaagtgctt tcgattttca aatacctaaa
    82741 aaattagcgt ccgtttttgc tagtgatttg gatcaaaaaa atcttgttga cggaatcgat
    82801 catccatttt tcttaaaaga aaccggcttg ggtaaagaag ccgctcgctt gactagcccc
    82861 gataaaagaa tccaagtaga tattgctaca gatgcttcta gtgtggttat tttcactgca
    82921 aatttcggca cagaaacacc agaaatgcgc aaccgaaaac tggcacatca cggtggcatc
    82981 acatttgaga ctcaaacagc tccaggtgca gagcgcttct cagcatttgg ttcgattcat
    83041 ttaaaagccg gatcagtatt tgaaacagta acagaattca aaatcaaaac aagaaaggaa
    83101 taactcatca tggaaatcaa aagaagctta aacacaaaat ttgccgaaac attcggacct
    83161 aaaaaaacta cacaatactt ctcaccagga cgcatcaatt tgattggtga acacacagat
    83221 tacaatggag gccatgtctt ccccgcttcc atcacttatg gaacgcaagg tgtagcagca
    83281 cctcgagacg ataataaaat attagtttat tccacaaact ttgacgatat cggtgtcatt
    83341 agttttactt tagatgagct agaatatgat aaaaaagcaa actgggcaaa ttacgtaaaa
    83401 ggaatggtcc ttaaattaaa agaagctgga cactcaatcg atcatgggtt tgagttatta
    83461 gtggaaggaa caatccctaa tggtgcagga ctttccagta gcgcttcatt agaattatta
    83521 gtaggtgttg tattagaaga tctgtttgat ttaaaaacag atcgcttgga actagtccaa
    83581 acaggtaaaa aagtagaaaa tgaattcatc ggtgtcaatt caggtatcat ggatcagttt
    83641 gccatcggct tcggtgagct agatcatgca atcttattag atacaaatac gctgaaatac
    83701 gaaatggttc cagtgaaact agatggttat gcaatcgtca tcatgaatac gaataagcgg
    83761 cgggaattgg cagattcaaa atacaatgaa cgccgtagcg aatgcgaaga agccttggca
    83821 cgtttgcaaa aaactttgcc tatctcttct ttaggagact tagatgaaga agaatttgaa
    83881 tcaactattg accaaatcgg cgatgataca ttgatacgca gagctcgcca tgccgtttct
    83941 gaaaatcagc ggactttgaa ggcaaaagct gaattagaag ctgggaactt agaagcattt
    84001 ggtcaactgt taaatgattc tcaccactct cttcgctatg attatgaagt aactgggatc
    84061 gaattagata cactagtaga tgctgctcaa aaacaagaag gtgtcttagg tgcacgaatg
    84121 acaggagctg gatttggtgg ctgtgcgatt gctcttgtca aagaagaaaa tatacctgcc
    84181 ttcaaaaaca atgtctatga tgaatacatg aaagttgtcg gctatgctcc ggaattttat
    84241 gttgcacaca ttggaaatgg gacaacaaag atcgatccag aagctgttca tgtttgataa
    84301 aaaaatcaac gatctcagct aaaaacaaat agataaaaat aacctctcag caatttccaa
    84361 atgtgagcct tttgctcgta tttgaaaatt gctgtttttt attgacacgg aaagagaacg
    84421 tgtgttctaa ttgtgttgaa gaggtgattg ttatgtgggc gaatcaaaat ccggtatttg
    84481 tttatgaaaa agaaccttca agagatattt tatgtattga ctgcaaatct ttttacgcct
    84541 ccgtagagtg cgttgaaaag gatcttgatc cccttacaac taaattagta gtcatgtcct
    84601 atccgtccga ttcgacagaa acacggggta gcggattaat cttggcttcc agtcctgcag
    84661 caaaaaaagc ttacggcatc accaatatca gccgtgccag agatcttccc ttcccctatc
    84721 caagtgattt atatattgtt gccccaagga tggcctatta tatggaaaag aacagagaaa
    84781 tcaattctat ctataaaaaa tatgcagacg aagcgaacca tcatgtctat tccgtcgatg
    84841 aaagcttcct tgatgtaaca aatagcatgg cactctttgg taaaacaaat gcgtacgaca
    84901 tggctaaact gatccataaa gatgtgtttg agcagaccgg aatctacacg actataggaa
    84961 ttggcgataa cccgctactt gctaaactag ccttagacaa tggctcaaaa gacggaaagc
    85021 aaatgtttgc tgaatggcgt tatgaagatg taccagaaaa gttatggaaa atctcagata
    85081 tcactgactt ttggggaatc ggcaaacgaa cagcaaaacg tctgaaacaa atgggtatac
    85141 attctgttta tgatttagct cacgcggatt attatcactt gaaaagcaag ctaggggtca
    85201 tcggtactca gctttatgcc catgcttggg gcatcgatcg aagttttttg ggacaagaat
    85261 atacaccaaa atcaaaaagt atcggaaata gtcaaatcct agatagagat tatacaagac
    85321 gagaagaaat cgagatcgtt atcaaagaaa tggccgacca agtcggcact cgcttgagac
    85381 gatctgcagc aaaaacacaa gtagtcagct tatgggtagg atactcttta ggctatcttg
    85441 atccaaatgg caagaccggg tttcaccagc aaatgaaaat cgaagcgaca aatgctagca
    85501 gagatctagc agatgcttta ttgaccattt tccaccagca ttaccactac caggatattc
    85561 ggcgtgtagg cgtgaactgt tccgacctcg tatacgcgac aggtttacag cttaaccttt
    85621 ttgaagatcc tgaaaagcag ataaatgaag cgaaagttga ttttgttgtc gatacgatta
    85681 gaaaaaaata cggctttcaa tcaatcatcc atgcgcatag tctcttgcaa ggaggacgcg
    85741 ccatcgcacg tagttctctc gttggcgggc atgcaggtgg tatgagtgga ttagaaggtg
    85801 gaaaagatga gacggacagc aaaaaaattc attgactata acgagtatcg agatcggcca
    85861 tttggattaa aatgggggac tgcttttgcg atggaagaac tagtcaacgg tatcaaaaaa
    85921 atgaagaaga agcacgcaaa cagcctcttc ctaaacaaca aatgacattg caagaaatcg
    85981 atagtatact gacagaagcc tttttatctc gtaaagcagt aatcattcag ctcaatttaa
    86041 aagatgaatt tggaagactc ttggatgagg tcgaagggca cttcattggt gaagcctatg
    86101 aagattactt tatgattgac catcagccga tattgtggga agacgtacgg tatattgagt
    86161 taaaggaaac aaaaaaatgg tttgtgacat gagaggttgt gacagaagtg atcaacttca
    86221 aaaaataaga aaggattttt cgaaaattgc ttcttaaatt tttgtggaat tttggcttat
    86281 ttttcgaaga agcaacttct ggaacaacgt atattagata tcagaggttg tgaaaaagtc
    86341 gcttagtttt gagtaacaag ccaaggcgct gatttcacaa cctctgtcta tctatccatc
    86401 tattcggtaa gattcatgca tgacgtcttc tttatttagt atgtagagcc ctttttcttc
    86461 tgaccattca acataaatca gctgttttac atctgcatag ccttctttct tcaagttctc
    86521 cataagccat gcttcagtca attgattgga ctgaagcact ttatgctgaa tttgcccttc
    86581 atctacaagc aggatcgata aagctttgtc ttcatctgat tttttcaata cactcatttg
    86641 accggcattc tctaggataa catgtttggc attttcaaga aaaaagcatt cttgctgtct
    86701 taagattgct cgcaactgct ccatctcgat atggttattt gtcaactctg tcatgttgat
    86761 gacgccgtct ttgattagaa cagatggctc gcctttgacc caacgattga ccttttcatt
    86821 tttttggacg atacgttcga taccataaat cattactgcc caaagcgcaa tggcaaatag
    86881 gacatgccct acatggacat tgtcatcata ggttgattct tctaagatcc cacctaaaac
    86941 aagcgtatag actaaatcaa acggtgtgat ttctgacatg gatttcttcc caagcaaacg
    87001 taccactaat aataaaccga tcaacccgaa caccagtttc attgtaattg aaaaaatcat
    87061 tttttctccc cctaactatc tgttaattaa attatatatg ctttctcacg aacacgcatg
    87121 gaatatacaa ggaagaaatg tatcctttta ctaaaaaaag gactgtgaca ctgtagtgac
    87181 ccccaaaagt tagacttttt tggagtggag aaatccactc ctttttttta tgctctaaaa
    87241 tgatattttt acacaaccgt tacggttgtt ttacgaaatt ggacg
//
LOCUS       DAFKHN010000003        86160 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFKHN010000003 DAFKHN010000000
VERSION     DAFKHN010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 86160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.003"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(440..943)
                     /locus_tag="LY912_000170"
     CDS             complement(440..943)
                     /locus_tag="LY912_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBM6953896.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1302..2327
                     /locus_tag="LY912_000171"
     CDS             1302..2327
                     /locus_tag="LY912_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBM6953897.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2650..3528
                     /locus_tag="LY912_000172"
     CDS             2650..3528
                     /locus_tag="LY912_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBM6953898.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            4004..4120
                     /locus_tag="LY912_000173"
     CDS             4004..4120
                     /locus_tag="LY912_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBM6953899.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            5048..5386
                     /locus_tag="LY912_000174"
     CDS             5048..5386
                     /locus_tag="LY912_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953900.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5480..5710
                     /locus_tag="LY912_000175"
     CDS             5480..5710
                     /locus_tag="LY912_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953901.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            6110..6481
                     /locus_tag="LY912_000176"
     CDS             6110..6481
                     /locus_tag="LY912_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBM6953902.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(6755..7447)
                     /locus_tag="LY912_000177"
     CDS             complement(6755..7447)
                     /locus_tag="LY912_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBM6953903.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7450..8235)
                     /locus_tag="LY912_000178"
     CDS             complement(7450..8235)
                     /locus_tag="LY912_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBM6953904.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            8472..9872
                     /gene="lacG"
                     /locus_tag="LY912_000179"
     CDS             8472..9872
                     /gene="lacG"
                     /locus_tag="LY912_000179"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBM6953905.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            9897..10214
                     /locus_tag="LY912_000180"
     CDS             9897..10214
                     /locus_tag="LY912_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBM6953906.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            10227..11900
                     /locus_tag="LY912_000181"
     CDS             10227..11900
                     /locus_tag="LY912_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBM6953907.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            11914..13545
                     /locus_tag="LY912_000182"
     CDS             11914..13545
                     /locus_tag="LY912_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBM6953908.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(14036..15601)
                     /gene="guaA"
                     /locus_tag="LY912_000183"
     CDS             complement(14036..15601)
                     /gene="guaA"
                     /locus_tag="LY912_000183"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBM6953909.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(15660..16583)
                     /locus_tag="LY912_000184"
     CDS             complement(15660..16583)
                     /locus_tag="LY912_000184"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBM6953910.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            16779..17384
                     /locus_tag="LY912_000185"
     CDS             16779..17384
                     /locus_tag="LY912_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBM6953911.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            17692..18708
                     /locus_tag="LY912_000186"
     CDS             17692..18708
                     /locus_tag="LY912_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBM6953912.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            18849..20150
                     /locus_tag="LY912_000187"
     CDS             18849..20150
                     /locus_tag="LY912_000187"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBM6953913.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            20196..20858
                     /gene="deoC"
                     /locus_tag="LY912_000188"
     CDS             20196..20858
                     /gene="deoC"
                     /locus_tag="LY912_000188"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBM6953914.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            20879..21277
                     /locus_tag="LY912_000189"
     CDS             20879..21277
                     /locus_tag="LY912_000189"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBM6953915.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            21343..22425
                     /locus_tag="LY912_000190"
     CDS             21343..22425
                     /locus_tag="LY912_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBM6953916.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            22637..24199
                     /locus_tag="LY912_000191"
     CDS             22637..24199
                     /locus_tag="LY912_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6953917.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            24192..25325
                     /locus_tag="LY912_000192"
     CDS             24192..25325
                     /locus_tag="LY912_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6953918.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            25325..26281
                     /locus_tag="LY912_000193"
     CDS             25325..26281
                     /locus_tag="LY912_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6953919.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            26380..27546
                     /gene="deoB"
                     /locus_tag="LY912_000194"
     CDS             26380..27546
                     /gene="deoB"
                     /locus_tag="LY912_000194"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBM6953920.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            27570..28388
                     /locus_tag="LY912_000195"
     CDS             27570..28388
                     /locus_tag="LY912_000195"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBM6953921.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            28405..29112
                     /gene="deoD"
                     /locus_tag="LY912_000196"
     CDS             28405..29112
                     /gene="deoD"
                     /locus_tag="LY912_000196"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBM6953922.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(29410..30096)
                     /gene="gpmA"
                     /locus_tag="LY912_000197"
     CDS             complement(29410..30096)
                     /gene="gpmA"
                     /locus_tag="LY912_000197"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBM6953923.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(30268..30849)
                     /locus_tag="LY912_000198"
     CDS             complement(30268..30849)
                     /locus_tag="LY912_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6953924.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(30982..31665)
                     /gene="rpiA"
                     /locus_tag="LY912_000199"
     CDS             complement(30982..31665)
                     /gene="rpiA"
                     /locus_tag="LY912_000199"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBM6953925.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            31984..32397
                     /gene="rpsL"
                     /locus_tag="LY912_000200"
     CDS             31984..32397
                     /gene="rpsL"
                     /locus_tag="LY912_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBM6953926.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            32481..32951
                     /gene="rpsG"
                     /locus_tag="LY912_000201"
     CDS             32481..32951
                     /gene="rpsG"
                     /locus_tag="LY912_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBM6953927.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            33045..35132
                     /gene="fusA"
                     /locus_tag="LY912_000202"
     CDS             33045..35132
                     /gene="fusA"
                     /locus_tag="LY912_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBM6953928.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            35304..36491
                     /gene="tuf"
                     /locus_tag="LY912_000203"
     CDS             35304..36491
                     /gene="tuf"
                     /locus_tag="LY912_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBM6953929.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            36898..37206
                     /gene="rpsJ"
                     /locus_tag="LY912_000204"
     CDS             36898..37206
                     /gene="rpsJ"
                     /locus_tag="LY912_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBM6953930.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            37237..37866
                     /gene="rplC"
                     /locus_tag="LY912_000205"
     CDS             37237..37866
                     /gene="rplC"
                     /locus_tag="LY912_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBM6953931.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            37894..38517
                     /gene="rplD"
                     /locus_tag="LY912_000206"
     CDS             37894..38517
                     /gene="rplD"
                     /locus_tag="LY912_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBM6953932.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            38517..38807
                     /gene="rplW"
                     /locus_tag="LY912_000207"
     CDS             38517..38807
                     /gene="rplW"
                     /locus_tag="LY912_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBM6953933.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            38846..39679
                     /gene="rplB"
                     /locus_tag="LY912_000208"
     CDS             38846..39679
                     /gene="rplB"
                     /locus_tag="LY912_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBM6953934.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            39722..40000
                     /gene="rpsS"
                     /locus_tag="LY912_000209"
     CDS             39722..40000
                     /gene="rpsS"
                     /locus_tag="LY912_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBM6953935.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            40023..40370
                     /gene="rplV"
                     /locus_tag="LY912_000210"
     CDS             40023..40370
                     /gene="rplV"
                     /locus_tag="LY912_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBM6953936.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            40384..41040
                     /gene="rpsC"
                     /locus_tag="LY912_000211"
     CDS             40384..41040
                     /gene="rpsC"
                     /locus_tag="LY912_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBM6953937.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            41043..41477
                     /gene="rplP"
                     /locus_tag="LY912_000212"
     CDS             41043..41477
                     /gene="rplP"
                     /locus_tag="LY912_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBM6953938.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            41467..41655
                     /gene="rpmC"
                     /locus_tag="LY912_000213"
     CDS             41467..41655
                     /gene="rpmC"
                     /locus_tag="LY912_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBM6953939.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            41680..41946
                     /gene="rpsQ"
                     /locus_tag="LY912_000214"
     CDS             41680..41946
                     /gene="rpsQ"
                     /locus_tag="LY912_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBM6953940.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            42004..42372
                     /gene="rplN"
                     /locus_tag="LY912_000215"
     CDS             42004..42372
                     /gene="rplN"
                     /locus_tag="LY912_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBM6953941.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            42409..42717
                     /gene="rplX"
                     /locus_tag="LY912_000216"
     CDS             42409..42717
                     /gene="rplX"
                     /locus_tag="LY912_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBM6953942.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            42745..43284
                     /gene="rplE"
                     /locus_tag="LY912_000217"
     CDS             42745..43284
                     /gene="rplE"
                     /locus_tag="LY912_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBM6953943.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            43303..43488
                     /locus_tag="LY912_000218"
     CDS             43303..43488
                     /locus_tag="LY912_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBM6953944.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            43524..43922
                     /gene="rpsH"
                     /locus_tag="LY912_000219"
     CDS             43524..43922
                     /gene="rpsH"
                     /locus_tag="LY912_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBM6953945.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            43954..44490
                     /gene="rplF"
                     /locus_tag="LY912_000220"
     CDS             43954..44490
                     /gene="rplF"
                     /locus_tag="LY912_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBM6953946.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            44651..45007
                     /gene="rplR"
                     /locus_tag="LY912_000221"
     CDS             44651..45007
                     /gene="rplR"
                     /locus_tag="LY912_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBM6953947.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            45028..45528
                     /gene="rpsE"
                     /locus_tag="LY912_000222"
     CDS             45028..45528
                     /gene="rpsE"
                     /locus_tag="LY912_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBM6953948.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            45543..45722
                     /gene="rpmD"
                     /locus_tag="LY912_000223"
     CDS             45543..45722
                     /gene="rpmD"
                     /locus_tag="LY912_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBM6953949.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            45766..46206
                     /gene="rplO"
                     /locus_tag="LY912_000224"
     CDS             45766..46206
                     /gene="rplO"
                     /locus_tag="LY912_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBM6953950.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            46206..47501
                     /gene="secY"
                     /locus_tag="LY912_000225"
     CDS             46206..47501
                     /gene="secY"
                     /locus_tag="LY912_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBM6953951.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            47563..48210
                     /locus_tag="LY912_000226"
     CDS             47563..48210
                     /locus_tag="LY912_000226"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBM6953952.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            48401..48619
                     /gene="infA"
                     /locus_tag="LY912_000227"
     CDS             48401..48619
                     /gene="infA"
                     /locus_tag="LY912_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBM6953953.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            48652..48768
                     /gene="rpmJ"
                     /locus_tag="LY912_000228"
     CDS             48652..48768
                     /gene="rpmJ"
                     /locus_tag="LY912_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBM6953954.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            48786..49151
                     /gene="rpsM"
                     /locus_tag="LY912_000229"
     CDS             48786..49151
                     /gene="rpsM"
                     /locus_tag="LY912_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBM6953955.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            49179..49568
                     /gene="rpsK"
                     /locus_tag="LY912_000230"
     CDS             49179..49568
                     /gene="rpsK"
                     /locus_tag="LY912_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBM6953956.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            49648..50586
                     /locus_tag="LY912_000231"
     CDS             49648..50586
                     /locus_tag="LY912_000231"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBM6953957.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            50614..50994
                     /gene="rplQ"
                     /locus_tag="LY912_000232"
     CDS             50614..50994
                     /gene="rplQ"
                     /locus_tag="LY912_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBM6953958.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            51266..52105
                     /locus_tag="LY912_000233"
     CDS             51266..52105
                     /locus_tag="LY912_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBM6953959.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            52081..52950
                     /locus_tag="LY912_000234"
     CDS             52081..52950
                     /locus_tag="LY912_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBM6953960.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            52940..53737
                     /locus_tag="LY912_000235"
     CDS             52940..53737
                     /locus_tag="LY912_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBM6953961.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            53940..54686
                     /gene="truA"
                     /locus_tag="LY912_000236"
     CDS             53940..54686
                     /gene="truA"
                     /locus_tag="LY912_000236"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBM6953962.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(55141..57810)
                     /locus_tag="LY912_000237"
     CDS             complement(55141..57810)
                     /locus_tag="LY912_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBM6953963.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(58048..58236)
                     /locus_tag="LY912_000238"
     CDS             complement(58048..58236)
                     /locus_tag="LY912_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBM6953964.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            58506..58868
                     /locus_tag="LY912_000239"
     CDS             58506..58868
                     /locus_tag="LY912_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBM6953965.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            58920..60602
                     /locus_tag="LY912_000240"
     CDS             58920..60602
                     /locus_tag="LY912_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBM6953966.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            60719..62755
                     /gene="recG"
                     /locus_tag="LY912_000241"
     CDS             60719..62755
                     /gene="recG"
                     /locus_tag="LY912_000241"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBM6953967.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            62804..63805
                     /gene="plsX"
                     /locus_tag="LY912_000242"
     CDS             62804..63805
                     /gene="plsX"
                     /locus_tag="LY912_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBM6953968.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            63927..64169
                     /gene="acpP"
                     /locus_tag="LY912_000243"
     CDS             63927..64169
                     /gene="acpP"
                     /locus_tag="LY912_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBM6953969.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            64437..65441
                     /locus_tag="LY912_000244"
     CDS             64437..65441
                     /locus_tag="LY912_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6953970.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            65442..66386
                     /locus_tag="LY912_000245"
     CDS             65442..66386
                     /locus_tag="LY912_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6953971.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            66386..67348
                     /locus_tag="LY912_000246"
     CDS             66386..67348
                     /locus_tag="LY912_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6953972.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            67375..68289
                     /locus_tag="LY912_000247"
     CDS             67375..68289
                     /locus_tag="LY912_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6953973.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            68315..70096
                     /locus_tag="LY912_000248"
     CDS             68315..70096
                     /locus_tag="LY912_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBM6953974.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            70444..71130
                     /locus_tag="LY912_000249"
     CDS             70444..71130
                     /locus_tag="LY912_000249"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBM6953975.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            71150..74731
                     /gene="smc"
                     /locus_tag="LY912_000250"
     CDS             71150..74731
                     /gene="smc"
                     /locus_tag="LY912_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBM6953976.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            74740..75549
                     /locus_tag="LY912_000251"
     CDS             74740..75549
                     /locus_tag="LY912_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBM6953977.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            75560..76558
                     /gene="ftsY"
                     /locus_tag="LY912_000252"
     CDS             75560..76558
                     /gene="ftsY"
                     /locus_tag="LY912_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBM6953978.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            76745..79012
                     /gene="gshAB"
                     /locus_tag="LY912_000253"
     CDS             76745..79012
                     /gene="gshAB"
                     /locus_tag="LY912_000253"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBM6953979.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(79101..79553)
                     /locus_tag="LY912_000254"
     CDS             complement(79101..79553)
                     /locus_tag="LY912_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBM6953980.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            79703..80653
                     /locus_tag="LY912_000255"
     CDS             79703..80653
                     /locus_tag="LY912_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBM6953981.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            80646..81605
                     /locus_tag="LY912_000256"
     CDS             80646..81605
                     /locus_tag="LY912_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBM6953982.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            81602..82357
                     /locus_tag="LY912_000257"
     CDS             81602..82357
                     /locus_tag="LY912_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6953983.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            82380..83333
                     /locus_tag="LY912_000258"
     CDS             82380..83333
                     /locus_tag="LY912_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBM6953984.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(83977..84273)
                     /locus_tag="LY912_000259"
     CDS             complement(83977..84273)
                     /locus_tag="LY912_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBM6953985.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            84628..84984
                     /locus_tag="LY912_000260"
     CDS             84628..84984
                     /locus_tag="LY912_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBM6953986.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            84994..85893
                     /locus_tag="LY912_000261"
     CDS             84994..85893
                     /locus_tag="LY912_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBM6953987.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        27858 a        15383 c        18498 g        24421 t
ORIGIN      
        1 acttctaaaa actactgttt ttttcctttg aaatgccttc aaaaagtagg atcaggcaga
       61 atatactggc agaatcaagg agaagggagc ctaaataagg agaaaaacca tagaaaatat
      121 aaagtaatta cttataaaac aagcttttta tagaaaaata atatacctga gtagggtata
      181 aattaagacg gaattccttt ctagattgag atattgacta ggaagaatgt taagatttta
      241 agcctttaag ctaaaaaaaa accctttttg ttaaataagg ggaatatagc ctgtcagttt
      301 caaactgcaa gtcgtcctgc tgcaataata tagtagatta gagatgaaaa tagatttttt
      361 taaaccaatg actgaataaa aagaccgtca tagatacaca ttggaatgtg tctattacgg
      421 tcttttttta cgaacgattt tattgaagac ggacagttcg ggtcaaaaat aaaaaagcta
      481 cgatcagaaa taagaataaa atgtatccca aaataatggc tagacggtct aacttatttg
      541 tcgatagatg tttgtttaga agttgatagg cccataaacc tatcagtcct cctgttgtat
      601 tagttatcaa atcagtgatg tccgctacgc caataccgaa taggaattga atcaattctg
      661 ccaagaagct tacaaggaaa ataatcccta attttttaga aaaagaaagt ctcttgaaat
      721 tgacattcaa aagcacccca aaaggaaaaa agacaatcaa gttataagtg gtctcacgta
      781 ataccgtcgt attttcaaaa gaaaaagtag aaaaagggac gagattgaca ttgctgtaag
      841 aataagtgag aaattgtgga agattaaatg atagcttgaa taaaatcaac cataatagaa
      901 agaataaata aatccctaat aaaaattttg atacataccg catagacatc tcctccattt
      961 aaaaagtata ccatcgaaaa ccgctgaaaa atcataaaaa agtatgaagt ttaaggacca
     1021 acgtagttat cgtacgaaaa ttagaagctt ttttttgttg ggaatccggt ttctttaaca
     1081 aagctaagat agcgagttgc ttggaaaagt tgctatcttt tttctgtcaa aacgactcgg
     1141 aatgttcgtt ttttgttcta atttctccaa gttgtttact ttttgatact aagtttatga
     1201 aaaatcaaga aatagttgtt atactaggta atgctgacaa acgggattgg catttcatct
     1261 tggttcagct ttttttccaa ttactaggaa ggagggatag attgttcaag acttattttc
     1321 gtttcaataa aatacaagat aatccttttc gtatcatgaa tctgatgcta cttatcttta
     1381 ttgtattatg gttaggttac ataaatcatg attttttgat ttcaagtttt tcatcattag
     1441 ggatctttac ttttttctat tatcaaaaca taccgatgaa atatttgctg aaacgtatgt
     1501 ttctgatcgg ttgcggactg ttggttgctt tcgttttggg gatcttatcg acttatgttt
     1561 tatggcttga accatttgcc gtagctttgg ttgctttttc cagcagattc gtgttgcgat
     1621 tattccatat ttctaaacca ggtggcttgt tttttgcgat gctttctgcc atgggaacga
     1681 gcatgcagct gccaatcgct caattaccga tcgtctcact ttattttttt atgggtgtcg
     1741 tttttgccct gattgcggca gtgattacaa aattactgga ttcacggcct gagcagacaa
     1801 ttgaaaaagc aactttaaaa gaaagatttc acgaagagcc tttagtgatc attgattctg
     1861 ttttctacag cgctgcctta tttctttccg tttatgtcag tcacggcttg aatctgcata
     1921 atccttattg gttgaccttg tcatgtgcat cgattttgct agcagaaaac ttggatgcga
     1981 tgaagcatcg acaagtccaa tatctgattg gatcgatggg tgggttatgt gtgtcggcat
     2041 tcttgtcatt tgtgccgttt acgcagttgc agaccatttt tctgatcact tttctatatg
     2101 gaatcgcaca atttctagtt gctagaaatt atgcagttgc taatattttt cttaatccga
     2161 tggcgttgat gctatctaca cttattcgtg gagcatactt gatttctttg atcgaatatc
     2221 gttttttagg gatcgtcata ggaagtttca tcggtttagg tgttgcgtgg gtaatgacgg
     2281 ttggtttgca acattattta acggttgttc gtcaaaaatt agaatagaag gacaaatata
     2341 tgtgccaaaa gaggttatga caagattttt gtcacaacct ctaattcaag gtgttcaaaa
     2401 gccagattct cagcattaag tcaaattcac acaaaaatgt ggaaaggaac tttcaaaaaa
     2461 attttatatt tattctatca aaaaattttg tttatgatgg taactgaata aactttcctg
     2521 agatggtcaa tgctttcctt gaaagtctta cagatattct ttcttcatag aaagtttaag
     2581 ttttatagtt agtgtacaat aaaagtatgt ttataccata tggtgtccgg ataatcagtc
     2641 atttaaacaa tgaggttcaa agatatgaaa aggggaaatt tgatgaagaa aataagcaat
     2701 gaaatccaaa ttctggcaga aactttaact cttcccaaag tcgttataga gcaaatgatt
     2761 gtacaagcaa aaaacatcct tgatgaggtg tttgagcaat atagtcatga actaatggat
     2821 cctaataaag caaaggcgac tgcaaagaaa atagacaaag tctatgaaga ggaacctttt
     2881 gcagcattag ctatttatct atatgcagct tctcaaagtt ggaaaaaaat ttatcaacca
     2941 ttgaagattc caagaactat ctatttggca acaatgaatg cttttactag atttattcat
     3001 gaacatttcc aagtaacagg aagctatcgc tttgaccgtg gtttttggat ttggcattac
     3061 actagtggct tgatctttcg gattggtgaa ttggagtacg aaatgacata ttttccgaaa
     3121 gggtacacgg atctaagatt agaaggaaag cagtgccttt ctcttcatat tccttccgat
     3181 gcagatttat ctcagaataa gataagagat agttacgaaa gtgccattcg tttttttgaa
     3241 ctttattttc ctgattacca ttaccaagtg atgtacacag atacttggtt actatcaccc
     3301 aatcttacta aatggttgaa aaaagagtca aaaatctgtc tttttgcagc cgattatcga
     3361 ttattatcag ttgatgaaca ggacgatagt ggagtccctt ggatctttgg acgagtagat
     3421 gcccaaatac atgattatcc agaaagtacg agtttacagc gacaagcaaa agagcaattg
     3481 cttgcaggcg agcacattgg ctctggctta ggtattctta cttcataagt ttagtacttc
     3541 gaaatagttt aaaagagcgt gagacaaaag taaagaacac ttttgtctca cgctctaaac
     3601 acgtataaac ggcggaagca gaagcaactc cttcggaaat aagctgaaat tcacaaaaat
     3661 ttgaaaagca attttcgtga atttcttctt gtttcttgga gttaaacgct tctgtcccag
     3721 cctctttttt agtgttctat cgaacacaca gtacgttcaa taggtaaact agctataaca
     3781 atagatatta aagttaacgg acaagagggc cttttttagg tagctaaaac gtaataatga
     3841 aaatttattt ccagagatag gagtcaatca gctagtctga tcgactgttt taacaagttg
     3901 actttcattt taacttttga taccatttaa aacacaaatc gtaattgttt cgatttgtgt
     3961 tttttagcat gactacaatc aaagaagaaa gtgggtcgtc catatggaaa aaacagatat
     4021 ctcaagtgca taccgccgct tgaaaagccc aaatatcaaa acacgaaaac gtgcgctgaa
     4081 gatcatcaaa gatgtgaaac ggaatagtgg gaaaaggtaa gaagaaggaa acttaattaa
     4141 aaaaatagcc gaaaaacgtt tttcggctat tttcaataat cggtttttgt gtaaggtttc
     4201 cgaaagaact gctgttgatt ttccattttt aacatatgat aaattggtag aatctttctt
     4261 ttcaaattga taccattccc taattccagt tatatagtta actacagaac cacaaagcac
     4321 gtacgtttat aaaagtatta tctgtagtta tttttcaatt ccctttcaac ctcttatttt
     4381 gaccagtagt attgatcact ttacctttta acacctttgt tcgtttttga aacattttta
     4441 gtcaagaatg gaaacgtaac tacataatca aaggttttgc gaaatatttc atgaaatatt
     4501 tcatgtagaa gcgagcaata cggttgcaaa taaccattat cgtttaataa gcagttacga
     4561 aagctcccaa tatctctaac gttcagctca ctccatttct tttcttcaaa aaaatcagtg
     4621 attcgtatct ctttctattt gtcgaaaaag ttaactttaa aaagtaacgc cgaaaaaata
     4681 tgcaaaaaaa taaaaaagca gttactattg ctagaataac atcaaggaat aataagtttt
     4741 ggttttcaga taatagtcga taagttgtgt attggaattt tagatacagt aataaagtat
     4801 ttttcatgaa attttgtgag aatcactatt acaagtatct ttaattaaat taatggttaa
     4861 ggaggaactt aaagtagaat gtaaatgaat agttgtagtc agtcgattgt gatactagac
     4921 tcaaagttgc aggaataagt ttttcaattt gtgattggaa gataaaaaat gaaaaagaag
     4981 ggcttttttt tatactttgt tgattgtagt gtttattttc cctctgttta gccaagtaac
     5041 attttctatg actcaaccag tttcaagtga ggaacatgat aacctttttc gtgctacaga
     5101 agagtttaag aaatatcagg aaaatattgt tccggagact ccattagcta gtgagccaat
     5161 tactgatatt gatggaaacc aaataggatg gtatatacag tacgaagtta tggtggtaaa
     5221 taatgactca atagtaaaaa atacagtagg cttagagcta acaccgattg aaaaggtgag
     5281 ttcattgtta acgtatattt atactgatga aagtgacgag actgagatca ttttaacgga
     5341 ttactcaaaa attgctactg ataaaaagta tatattgtgg atgtagacac tagtgaaata
     5401 ctttatgata tagaaattga tgaaaattta ctagatgtag cacaagaaat cgatcatcaa
     5461 aagcaggaag ctattcgata tgctggtaga aaagggaaaa gaaaatattt attacgtgaa
     5521 tgtagcaaaa gttagagaag atgaaaatga gtggaaagaa ttcaagagtc gctactcaat
     5581 taactcgact ccgacattta cagtttacag agaaggatcg atagaaaaaa ctgttttttg
     5641 gactaaagaa agtggaatgt ctttagctga agtagaagag tttttggatt atgttagtat
     5701 gcaacagtaa gggagttctt attatgaaaa attttgacac atattatgtt attgtttttt
     5761 cgatatcttt gctgttaata ttactaactt taatgcagta taaagagtat ccagagtatt
     5821 ttattttaac ttttgtatat ttagtaagta gctacacact tctatataaa ttcagaagtt
     5881 cttctagagt ttctaaagtt tgtttcttaa ttagcttatt gattctataa tatttttgat
     5941 ttatatagga aattaaaaat attatagaat caacactcag agaacgggtt ggtttttaat
     6001 agatttaata agtactgata atgaaatttc tcctggttgg gaaaacgaag ttggttaccc
     6061 tgtagaagaa ttttttcaag attactttgc ggagtatgcc gataggataa tgagagatta
     6121 cgtaacagat aaaactcaag aagtcatcaa tcaatcccag tcattaaatg aattatctga
     6181 taaggcgaaa gaagaagcag ttgccattat ttcttcaggg attagtgact atattgatat
     6241 gagtggtgaa atcaattatg gcgataaaga caaaattgta cgcatgataa aagcttttat
     6301 caaaactttt gatgtgaagg cagatcttaa gtttaatgat acttacctag taggaaaatt
     6361 aattaatatc cttgggacag agaaagatac ggaaacgttt atttcctctt tgtctatgtt
     6421 gtttacagat aagcattttt caactcagct tggtggagag gaactagtgg aaatctttta
     6481 accattacgc ccagcattaa taaaagtata tcaaaaaagt actcctgatg atttttaaga
     6541 ttggtttgag aaataatgtg aaaacactat ttttaatgtt aattatagat agagatgaac
     6601 gcgtcatatg gttaaaagaa tgaaaaagtc aaagatacac tgctatattt cactaaggat
     6661 atagcagtgt atctttcatg tcgtttcact ggcagttttt tataaaagga ggtgtgcatt
     6721 tcagttgctt ttctttggta gttagttgaa tcgtttaaga attaacggat gtggcagaca
     6781 ggtgctctgt ccaaaaacca gtaaaatctt tgatggttcc atctttattt agctgtgcct
     6841 gttcaaatac tgttttgttt ttaccgaatg gatcaattgc aataattgtt ccgatccccg
     6901 cacgtttggc agcaagtaat cctgagtaag catcttcgat aacaagacaa tcagccggag
     6961 ctaagctcag tttgtctgcc gctttaagaa aaatatccgg ttgcggtttc ccagggaaag
     7021 agccgtcgtc atagacaatc ttgtcccagt caaaccagcg ggctaaatcg aaaatatcaa
     7081 aataaaaagc aacattctct ttgacagtag ccgtggcaat cgttaatgga atctgttggt
     7141 cagtcagctg gtcaagagtc gcttcaagcc cttttgtcaa ctgaagctcg ttttcatttt
     7201 gcaagcaaag catacgataa tagctttctt tttcttctga caatacggcg atctcagagg
     7261 cggtcaaatg ctctgaaatg aaatgtttca aaatctccgt attcgtccga ccatgaatat
     7321 tttttaaaat atcctcgtct gataaaccat cttttgtatg atcatgtatc atatgcagcc
     7381 aagcagcttc atgcagatga gagtccaaaa acattgttcc gttgaaatca aatataatcc
     7441 ctttcatagt tacgctccta tagtggtatt ttcggttgaa tcagcaattt gcagatcgac
     7501 atattgtgca tagtgctctt gaacctcccg cgagatctgg cgatccgtaa tgagcagatc
     7561 gaaatcatgc aaattataaa acacataaaa atcatctcga ttgaattttt tattatcaac
     7621 gagtagatat ttcttacggg aattatttag agcgatctgc tgtgcttctc cttcttcggt
     7681 actgtaagta gagatcgctt cgttgtgaac gccatttgaa ctgataaatg cttttgtaaa
     7741 ctttagtctt cttaaattgt cgttggtgat cggtccgaca aatgcgccgg tatttttccg
     7801 gaaatcaccg ccaatcagta gaatttctgg tccatctgct tgagcaagaa tatcaaaaac
     7861 tggataatta tttgtaatga tccgaatttt cttgttcagt aaatgcgtcg ccaatagttc
     7921 gattgttgta cctggtccta agaaaatcgt ttctccctcg tgaatcaagg aggctgctgt
     7981 ggcagcaatt tctttttttt cttgaatctg cagagtggct ttttcagtgt gagaaagttc
     8041 ttgatctaaa gtgtaggaaa gactttgagc ccctccatgg acacgcagca gcttgcccga
     8101 tttttctaat tcatctaaat ctctgcgaac ggtcatatca gaaacatcta attgattgat
     8161 gatttcatta acggtaagga ttcctttttt attgaccatt tctacgatag taagcaatct
     8221 ttcttttttc aacattgtct tcacctctaa tttaaggata atctatcata taaacggaca
     8281 acagtcaatc taattcgaac aaaagtaaac atttagggtg gtttttatgt ttgttacaat
     8341 agattttatt gctgttttct ggtttttatg attatttgtg tttgtttttg ttgacaaatg
     8401 ttttggatgc gtttacaatg caatcagtta gaaagagcga aaactgatta tagatttgag
     8461 gagagatgta catgcttaaa ttaccagaag attttatttt tggcggagcc acagcagcct
     8521 atcaggttga aggagccact aaggaaggtg gcaaaggcgc tgttgcttgg gatgactttt
     8581 tagaggaaca agggcgattc agtcccgatc cggcaagtga tttttatcat caatatgcaa
     8641 aggacattga attgtgtgaa cgttttggtg taaatggtct aagattatcc attgcttgga
     8701 gccgcatttt tcctgatgga gctgggaaac caaatccaga aggaatcgct ttttatcatc
     8761 gtgtgttcga agaatgtaag aaaagaaacg taacgccgtt tgtgacgttg catcattttg
     8821 atacccctaa acgtttgttt gaccatggag attttttgaa tcgagaaaca atagaagcat
     8881 ttgtttccta tgccattttt tgttttcatg aattcaaaga agtcaaggtg tggagtacct
     8941 ttaatgaaat ctatccagtt gcaaccaatc aatatttgtt aggtgttttc ccaccaggaa
     9001 tcaaatatga ttttacaaag atcgtcgcct gtcttcataa tatgatggtt gctcatgccc
     9061 gtgtagtgaa ctatttcaaa gaaaacgaac ttccgggtga aattggtgta gttcactcat
     9121 tagagacgaa atatgcggca acagacgcgc cggaagataa gcatgctgcc tttttagacg
     9181 atgcattgtc gatccgtttc ttattagatg ctacctattt aggctattat tcaactgaaa
     9241 ccttgactgc tcttgatgag atatgtgaag caaatcaggc cagctatcat tttcctgaag
     9301 aagatttcgt tgaattgaaa aaagcatcca cgcgtaatga ctacttaggg atcaatcact
     9361 accaatgcca ttttgtcaaa gcttacgatg gagaaaatgc aatccatcat aacggtacgg
     9421 gtgaaaaagg gacctctgtt tataaagtga agggaatcgg agaacgtatt tataaagaag
     9481 gaattcctcg aactgattgg gactggctga tttatccaga aggtctatat gacttgttgc
     9541 tgcgaattaa aagcgattac ccacattaca acaaaatcta tatcactgag aacgggatgg
     9601 ggtataaaga tcagtttgaa gatggcatta ttatggatca gccgagaatc gactatttga
     9661 gagtctattt ggaatcctta agcaaggcga taacagccgg ggtaaatgtg aaggggtatt
     9721 ttttgtggtc gcttatggat cttttctcat ggacaaatgg gtataacaaa aggtatggct
     9781 tgttttatgt tgattttgaa acccagaagc gttacccaaa agaatcagct tactggtaca
     9841 agttggtcag tgaaaccaaa acgattattt aataagtgat aatggaggaa gaaaagatga
     9901 ataaagagga attacaaatg cttggttttg agatcgttgc atattcaggc gacgctcgca
     9961 gtacattatt gaaattattg aaagaagtaa gacaaggaaa ctttgaacat gttgattcgg
    10021 cgttgaaaga agccgacgaa aatttaaccc ttgcacataa ttcgcaaaca aaaattttag
    10081 cggaagaagc atctgggaaa gagatggaga tgggattcat ttttatccat gggcaggatc
    10141 atttaatgac cactttattg ctgagagatc tgattcaaga ctttattgta ctgtacagac
    10201 agaatcaagg ataggagaag aacgctatgg atggaatcat taaacaaatc gaaaaaggga
    10261 aaccattttt tgaaaaaatc tcacgtaata gttatttagg agccgttcgt gacggatttt
    10321 taacagcgat gccagctatt ttattttcaa gcattttcat tttgattgct gcggttcctg
    10381 agatttttgg ttaccaatgg cctgaatctg tctccacatg gctatggaaa gtctataatt
    10441 attcgatggg tgttgtaggg ttactcgttt cagcaaccac tgctcgctgc ttggctgatt
    10501 cgatgaatcg tcgcttaccg aaaaacaaag taatcaacac cacctctgtg atgctggcct
    10561 ctgtggtaag tttcctgttg ttaagcgtct ctccgattga aggtggattt tcaacggaat
    10621 atatggggac aaagggacta ctggcttcct ttgtcgctgc atttttaaca gttaatttat
    10681 ataagttttg tgtgctgaaa gatattacca ttaaaatgcc taaagaagtt cctggaacga
    10741 tttcgcaaac cttccgagat atttttcctt tctctttttc agtatttgcg gccgttttaa
    10801 ttgatttagg cattcgacaa atcttccaaa tctcatttgc agaagcaatc attacggtgc
    10861 tgcagccgct atttacagca gctgacgggt acttaggaat cgctattatc tggggagcga
    10921 tggcgctgtt ttggtttgtc ggtgttcatg gaccgtcgat cgtggagccg gcaattgcgg
    10981 caattatcta tgccaatgtg gaaaccaatc tgcaattgtt caattccggt gaacaagctt
    11041 ctaaagtact gacggtgggt ttagggaatt ttgtaggaac tatgggagga actggggcaa
    11101 cattggttgt tccttttatc ttcctactct ttgctaagtc taagcagttg aaggcagttg
    11161 ggaaagcttc ctttattcca gtaagtttcg ctgtcaacga accattgcta tttgcggcac
    11221 ccatgatttt gaacccttat ttttttattc catttttgtt aacacctgtt gtaaacgttt
    11281 gcctgttcaa gttttttgtc gatgtattgg gcatgaacag ctttatgtac gttttgcctt
    11341 gggcaactcc agcaccgatc ggtttggttc taggaacggg catgggtatc ttagcttttg
    11401 ttctagcagc ggttctaatc gtcgttgact tcctgatcta tctaccattt tgcaaagcat
    11461 acgatgctgt cttagtagag aaagaagcac aaaaagcaga ggtgatcgca accgaggaag
    11521 gtgcttctgc cgatgtacgt gaggaagtac ctgtggcagc gagtcaagtt atcagcgatg
    11581 caaataaaga aatcaatgtg ttggtacttt gtgctggcgc agggacaagt gcgatgttag
    11641 ctaatgcttt aaaaaaaggt gcatctgaat cgaaagcacc gatcagtgca atggcgggtg
    11701 cttatggttc tcattacgaa atgctgcagg attttgatat ggtggtctta gcaccgcaag
    11761 tcaattctta ctatgatgat atcaaagaag acaccgatcg cttaggaatc aagctggttg
    11821 cgacaaaagg agcagaatat atcggattaa cgagagatcc tgaaaaagct gttcagttta
    11881 ttctgaacca atttcaataa aggaggagcc ataatgaaaa tgggaatttg gttgcgtaaa
    11941 gctgttttat ttgcagctgt gttaggggct ttgggggctg tttcaaaaac tgttgaagca
    12001 tctgccagcg aatttattcg cggagcagat atttcgatcc tgtcagatat ggaaaaatct
    12061 ggtgcaaaat attatgaaga cgatatttca aaagatgcct tagagatttt aaaaaataat
    12121 ggtgtcaact atgttcgact gcgtttgtgg caggatcctt ataatagtaa tggagaaagt
    12181 tatggagcag ggacaaatga tctggaaacg acgattgacc ttgcaaaacg agcaaaaaat
    12241 ctgggactta aggtgctgct ggattttcac tacagtgatt tttgggttga tcctgggaaa
    12301 cagaatcttc ctaaagcatg gcaaggtctg acctttgaag aaatgaatac ggcattgtac
    12361 gactatacaa agaacgttct gtcggaaatg aagcagctgg acgtttatcc tgatatggtt
    12421 cagatcggca atgaactgaa tagcggaatg ctctggcctt atggcaagtc ttggggagaa
    12481 ggcgggggag aatttgatcg attggctgct tttttgaagt ctggtatcca agctgttcga
    12541 gacactcaac ctaaaacaac tccagtaatg ctccacttag ctgatggtgg cgatacagga
    12601 gcatttactt ggtggtttga tgaaatcacg agtcgaggtg tgtcatttga tttaattgga
    12661 gtgtcgtatt atccgtattg gcacggttca atgaatgaac ttcaaaccaa tatgaatgcg
    12721 atcagccaac ggtatggtaa agaagtgatc gtagttgaaa cagcttatgg gcatacaaca
    12781 gcgaatgccg atactatgcc aaatgctttt ggtgaagccg aagcagctgc ggggggatat
    12841 gaaccaacac cgacaggaca agcagagtat ttgctggatc ttgccgatcg gattcaggca
    12901 gtaccgaata atcgcggggc gggcttcttc tattgggaac ctctttggta caacggaaat
    12961 gtgagttggg caacacaagc aggtatgaat tatctcagtg ttcaatccac tatgggaaac
    13021 gaatgggaca accaagcgat gtttgatttt gctggaaacg ccttgccaag cttgcgtgcg
    13081 tttaaacaag caggggcgca aataaatcta gttaaaaatg caagtttcga aagcgatgga
    13141 ccaacgacca gtccttccaa ttggcaaacc tggtttcaac aaggaaccgc taagggtacg
    13201 atcaaaacgg aagcgggcac tttttttggg gactacaaac taactttttg gcaggatcaa
    13261 gcatacgagg catcagctta tcaaaatgtt agtggcataa gcaaaggaac ttacacattg
    13321 agtgcctatg taatgtctgg gggagagttt gatactaatc agttatatat caaaaattat
    13381 ggtggagcgg aactaaatac tgcggttgtt aaaacaagtg aatggacaaa aattacaatc
    13441 aaagacattc caattacaac aggtgtttgt gaaattgggg tttatagcaa ggcttcagga
    13501 aatgcttgga cgaacgttga ttttgtttca ttggtgaaac aatagactgc ggatcgtttc
    13561 gattcaagat cggaggttcc cttcagccac atcgttagcg tagaaggcag gaatcgaacc
    13621 tgcacctcgc ctttgccaaa aataaccaga aacgatttcc agtcattttt accaaaacga
    13681 gtaaagcacc agacttcatc tacactttgt attatgctaa agagagttca acgatttcgt
    13741 aagaagcaat gaaaaaattg caaaaagttg tgcagataac ataaagtttg tttaagaaag
    13801 ggtaacctta gaattccgtc gtgaatatga tttgagcact tagatggata gaaaaaagtt
    13861 ctcggaaaac agttcgtttt tcgagaactt ctttttatga taagaatgaa acaaattaac
    13921 ttatattata gtctcttttg gtagggaacc atcttatttt taatgaaaat caagcatttt
    13981 agctattgaa gaatgttgat ttatagggat tccccctcca tattatgttg gctctttatt
    14041 cccactccac tgttgctggt ggtttagaag tgatgtcata cacgatacgg ttgacgtggg
    14101 ctacttcgtt tacgatacgt acagagattt tttgcaagac ttcccatggg atacgggcaa
    14161 agtcagcggt cattccgtcg attgaagtta cagcacggat accgactgtg tagtcgtaag
    14221 tacgtccgtc acccataaca ccgacagagc ggatccctgg aagaacagtg aaatattgcc
    14281 agatatcacg gtcaagtcca gcagctgcga tttcttcacg caagatagca tcagattcgc
    14341 gtacgatttc tagcttgtct tcagtgattt cgccaagaac acgaatacca agaccaggac
    14401 cagggaatgg ctgacgccaa acgattgaat caggcatgcc taactgagtc cctaattcac
    14461 ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa ttcaaattgc atatcttctg
    14521 gcagtccacc tacattatgg tgagatttga tcgtctgtgc tgtttctgta ccagattcga
    14581 taacgtcagt atacaacgtt ccttgtgcta ggaaagagac gccttcttca ccagcaagtt
    14641 ttgttgcttc gtcatcaaaa acatatacga attcattccc aatgatttta cgtttttgtt
    14701 ctgggtcaga tacacctttc aacttgtcta agaagcgatc tcttgcattg actttgatga
    14761 tgttcaagcc gaattttccg cctagacttt ccattacttg ttccgcttcg cctttgcgta
    14821 gcagaccgtg gtcaacaaag atagatgtca attggtcacc gatcgctttt tgtaaaagaa
    14881 ccccaacgac actagaatca acgccacctg aaagaccaag caagactttt ttgtcaccaa
    14941 cttgttcacg gattttttct acttgcatat cgataaagtt atccattgtc cagttacctt
    15001 cacagtgaca aacatcaaag gcaaagtggc gcagcaattc gattccgtat tcggaatgac
    15061 gtacttctgc atggaattgg ataccataaa aattacgtgt tgtgtcttgg atagaagcaa
    15121 tcggacaatc tttgcttgtt ccgactgttt caaagccttc aggaacttta gttaccaagt
    15181 caccatggct catccatact gtttgttgtt ttggtgtttc tttaaacaag acagcttgat
    15241 cgcttgttac ttctaacaag gctttcccat attcgcggtt tttagcaggc tctacggaac
    15301 cgccaagttt gtacgtgatc aattgcatac catagcaaat ccctaataca ggaataccta
    15361 aattgaagat ctcaggatcg atcccaaatg cattctcatc atatacactg tttggtccgc
    15421 cagaaagaat gattcccttt ggattcatcg cttttacttc ttctgcagta atgcggtggc
    15481 tcaataattc ggaaaagact ccaagatcac gaatacgtct tgtgatcaat tggttatact
    15541 gactaccgta gtctaatacg ataatctttt caacgttcgt catatcggca acgtttgtca
    15601 aatttattac ccctatccct ttaaatttta tctcaaaata gtcaaactat tttaaaatgc
    15661 taatattttc gcatgaaaat cgaatcgatg atatgatttt cagttttatg gagaattata
    15721 tcggctcttc ctcgtgtagg caagatatat tcctgtaaat ttttcaaatt cacatttttc
    15781 catacatctt ttgccatttt aaaggcttct tcacgatctc cgatagcaaa acgataataa
    15841 taattctctg gattttggaa agccgtatcc agtaacgcac caaaacgatc caaataccat
    15901 ttttcgatca gcacgggatc ggcatcgaca tagacagaaa aatcaaaaaa gtcgctgacg
    15961 tagatttgct gattcgcagg taattgaagc gtattgatcc cctcaacgat caagatatca
    16021 ggctgctgga tcaattcgta cttgtctgga atgatatcat acacatcatg tgagtaaaca
    16081 ggtactttta tctcttcctg accagatttt acacggttca agaaatcgat cagcatctcc
    16141 atatcataac tttcaggaaa tcctttacgg tccatgattc cacgctcttt taatatacga
    16201 tttggataaa gaaatccgtc agtcgtgatc agctgaacgt ttcttcgttt gaaggtacga
    16261 gacaaaatcg tctgcagcag tctggctgtt gtactttttc caacggctac acttccggcg
    16321 atcccgataa taaaaggcgg tacttctacg tatttatgaa gaaataaacc tttactcaag
    16381 aacaaagatt caaattcttt catataaaga taaatcagat gagcaagagg tacatagata
    16441 tctcgaacat cctgcatgga aatgcggtca ttcaaacttt tgatattatc tagttcatct
    16501 tgtgtcaaag gtgcttgccc attacgataa aattctcgcc attcttctct tgccacacgg
    16561 tagtagttca ttggatcatt catattagcc tcctgcgttc tcccatcaat ggaactattt
    16621 taacacaaaa taaacgcaaa ccccaccact taagagagat tgccgatctt tttgtataat
    16681 ctttataata gaaagaaacg gagtcttatt cttgacttgc gcacggatac ataaaaggat
    16741 agactgttgt catgaaagaa atgagaagga tggaagacat gacaaatcat tactattctg
    16801 aacgcccaga tacggcgcac gattttgaac aatgggcttt tgagttaaaa ggcagaacct
    16861 ttcaatttgt aacagattct ggtgtatttt cacgtgaaac agtggattat ggttcacgtg
    16921 tcctgattga tgctttcgat tgggaagagt tacctgatga aggaaagatc ttagatgtgg
    16981 gatgcgggta tggaccgatt gggttagctt tggcatttgc gacacagcgg tttgttgaaa
    17041 tggtcgacat taatgaacga gcggtaagtc tagcgcaagg aaacgcaaag cgtaaccaaa
    17101 tcgaacatgt tgatatccat caatcgaata tctatgaagc agttcatgaa gaaacctatg
    17161 cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa agttgtacat gaaattttga
    17221 caggcgcata tcctcggttg aagaagggcg gtacactgac aattgtgatc cagaagaaac
    17281 aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt tggtaatgca gaaatcgtca
    17341 caaaagataa aggatattat atcatcaaaa gtgtgaaaga ataactagct gaaaaatagt
    17401 ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt acgtatcagt tctttttttg
    17461 ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa aaagaaatag taggaacaga
    17521 gtcgttgttt tttacgataa aataaataag atacagaact tgtatagaag gctgccaagt
    17581 cggtagataa aggaggtttt tatcaaaaaa catactttcc ttttttctct attcttttct
    17641 tgggggtttt ggtacactga tagggaattt agatagaagg gagccaatag gatgaagctg
    17701 accatcagag atatcgcaga aatggcaggc gtatcagtaa caactgtctc acagattttg
    17761 aataacaaag gaagcagatt tagtgataag acaagaaaaa aagtgttgtc gatcgtgaat
    17821 gaacatcatt ataagcccga ttatttcgct tcaaatgtga tcaatcgaca ttcaaagacc
    17881 atcggaatga tcgtccctga tgtcactgat ttcttcttct ccaaactgat cgaaggtgta
    17941 gagagctatt tgaatccttt gggctatgtg atcatgttat gcaattctcg tcatagccaa
    18001 gaaaatgaga tcaagtattt acaagagctt tcccaccgct cagtggacgg aatcttgctg
    18061 gccacaccaa atattttacc tgagaaatat gcattagaca gcggttttta tcaaaaaatg
    18121 ccaatcattt taatcgatcg cggattgaat cgtcgggata acggacggct tatcgtaaag
    18181 gaatatgagg gcgcctatca agctgtttcg ctgtttattg aaaatggcca tacgaagatc
    18241 ggcatgctga aggaaaccac tggatactat caattagaag aacgtttcaa cggatatcgt
    18301 catgcgctga aagatcatgg cctgcctttt aatgggaaat ttgttgaaca tggagagttg
    18361 actgtccaag gtggatatac tgcatcaaaa aaattactca aacataaaga tatcacggct
    18421 attttttgcg ggaatgatgc catggcgatc ggatgctatc aggcgatcga tgaattgggc
    18481 aaaaaaatcc cagaagatat ctcagtcata ggattcgatg gattaaagct gtcagaatac
    18541 atgattccgc aattgacgac agtgcagcag ccaagttttg atattggatt ttatgctgca
    18601 cgtttcctga tcgatacgat cgaatttcct caaagaaaag ttccgaacaa agtgttcgaa
    18661 acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa agggctaact cggcggtata
    18721 ttgcttatgt aagcatttac aaaggctagt tagtgctttt tttattttta gtaaaccagt
    18781 ttactaaagt ggtttacctt tcctaaaaat aatgtataat accgaatgaa gacaaggagg
    18841 atcaggcaat gcgaatggtg gatctgattg aaaaaaagag ggatggaaac gagctgtcga
    18901 aagaggaaat cgagtacatc gtcacgaact atacgaatgg aaagattcca gattatcaag
    18961 tcagtgcatt attgatggca attttttatc aagacatgac aaatgaagaa atcacgaact
    19021 taacattggc gattgctaat tctggtgatg tcatcgattt gagttctctt gaaggaataa
    19081 aggtagataa gcattcgaca ggtggcgttg gtgacacgac cacattgatt ttagcccccc
    19141 tagtagctag tgtcggagtg acagtggcta aaatgtctgg acgcggtcta ggttacacag
    19201 gtggtacact agacaagcta gaagcaattc ccggatttca gatcgagctt tcggatgaag
    19261 aatttgtacg cattgttaat gaaagtaaag tagcggtaat tggtcaatca ggaaacttgg
    19321 caccggcgga caaaaaattg tatgccttgc gtgacgtcac agcgaccgtt gattctcttc
    19381 cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc aggagcagat gcaatcgttt
    19441 tggatgtgac cactggagac ggtgctttca tgaagaacat cgaagatgca agacgtctgg
    19501 caaagaccat gacgagcatt gggaaactgg ctaaccgaga aacagtggcg gttatctcag
    19561 atatgtcaga acctcttggc gaagctatcg gaaatagtct agaagttgtc gaggcaatcg
    19621 aaacattaca aggaaatggt ccagaagatc tagtagaaat gtgctacgcc ttaggaagcc
    19681 aaatggttgt tcttgctggc aaagctaaga caaccgatga agcaagaacg ttgcttcaag
    19741 aagctctgga atcaggtaaa gcgttagcaa aattcaaaga aatgatccaa aatcaagggg
    19801 gagacccagc gatcgtggaa catccagaac gaattttgac tgcacgctac acaatggagc
    19861 ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc aaatgaatta ggaattgctg
    19921 caatgatgct aggtgctggg cgtaaaacca aagaagaaga tattgatcac gctgttggat
    19981 tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg tgagtcacta ttgacgatct
    20041 atagtaacga cgaagaaatc acttctgtca ttgaattatt atataaaaat attgaaattg
    20101 gtgaatcggc aatgaagcca acgttgattc atgacatcat cacagaataa aggaaaaaag
    20161 cggactttac cgttttaaag aaaaggggaa aagaaatgga actaaaccga atgatcgacc
    20221 atactatttt gaaagcagac gcatctaaag aagctgtgat gcaaattatc gaagaagcaa
    20281 aaaaatacca tttttattct gtctgcatca atccagcatg ggttgcgcta gcgaaagaac
    20341 aattacaagg tgagccagta gccgtatgta cagtaatcgg gtttcctcta ggagcaaaca
    20401 cacccgagac aaaagcattt gaaacaacag atgccatcaa taacggtgca gatgaagtcg
    20461 atatggtcat caatatcggt gctttgaaat caaaggatga tcaacaagtc caaaaagata
    20521 tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt caaagttatt attgaaacat
    20581 cgttattaga tagagaagaa atcatccgag cttgcgaaat agcaaaagct gcaggcgctg
    20641 attttgtcaa aacatcaact ggtttctcaa caggcggagc aaaggtagag gatgtccgtt
    20701 tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc ttccggcggt atccataacg
    20761 aagaagaagc aatggcaatg atcgaagctg gtgctacaag aatcggaaca agcgcaggag
    20821 tagcaatcgt atctggttca actggtgaag gctattaatt ttttcaaagg agaagctcat
    20881 ggcagaactc aaacaagaat ggatcaacac agctattgaa gcgttagata aagcctatgt
    20941 tccttattcc cattttccgg taggcgcttg tctcgtaacg gaatcaggca agatttatca
    21001 aggcatcaac attgagaatg catcatttgg attaacgaat tgtgccgagc gcacagcttt
    21061 tttcaaagca gtatctgaag gagaaaaaac atttacgcat ctagtcgtag cggggcacac
    21121 ccccgatcct atctctcctt gtggtgcatg tcgacaagta atggcagaat tctgttcccc
    21181 tgatatgccg gttacgctag taggagacaa tggtgtgacg aaggcaacga ccgttcgtgc
    21241 actgctgcct tatgcattta ctgaaaaaga tctataactc atgttcattc agtcagctga
    21301 ctgttgaaaa ataaaacaat tattttagga ggctttacag aaatgaaaaa agcaaaatta
    21361 tttggtttag gtgctgtcgc actagcagca gggttatttt taggtgcatg cggcaacaac
    21421 ggctctactg attcatccgg tggcaaaagc tcatcagaca caacaactgc agcattgatc
    21481 acagacacag gtggtgtaga cgaccgttca ttcaaccagt cagcttggga aggactagaa
    21541 aaatggggga aagatcaagg actttcacga ggaaatgatg gcttccaata tttccaatct
    21601 tcaaatgaat cagattacat cccaaatatt gaccaagcat tgaatgctgg attcaaaacg
    21661 atttttggta ttggttataa actaaaacca gcgatccaag aacaagcaac aaacaataca
    21721 ggtacgaact ttgttattat cgatgatgtc atcgatggat tagataacgt tgtatctgca
    21781 actttcaaag acaacgaagc ttcttatctt gcaggtgttg cagcagctta tacgactgaa
    21841 acaaacgtag tcggctttat cggcggtgta aaaggtgaag taatcgatcg ttttgatgct
    21901 ggattcaaag ccggtgttga tgcaggtgcg aaagaattag gaaaagaaat caaagtattg
    21961 aatcaatatg ctggtgactt ctctgctcca gataaaggac gttcaattgc tcaaggtatg
    22021 tatgcacaaa acgcagatat catcttccat gcttcaggcg gtacaggtaa cggtgtattc
    22081 caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag tttgggttat cggtgttgac
    22141 cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg aaaagaaaaa cttcacattg
    22201 acatctacac tgaaagcagt tggaacagta gtagaagatt tggcacaaaa atcagcggac
    22261 ggtaaattcc ctggcggcga acacactgtt tatggattga aagaagacgg tgttggtcta
    22321 acagaaggac aactttctga cgaagcgaaa aaagcagttg atgaagcaaa agaaaaaatc
    22381 atttcaggtg acgtaaaagt tccagaaact cctgaagaaa actaaaacca tttctatagc
    22441 cttgttagac acatgtttga caaggctatg gtttgattag aacaagaatt gttcatttat
    22501 ccaagctgcc ttgtgacagt ttggataagg gaacaactcc ctgaagtaat gtttgtttca
    22561 aaagaagaac gctcactaag cgtgaatctt agtcaatcgt tgccctagat agaaatcgtt
    22621 aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata gaaatgcaga atattaccaa
    22681 agaatttgga acattcaagg caaatgacaa catcaattta caagtaaagg caggagaaat
    22741 tcatgcgttg cttggagaaa acggtgctgg caaatctaca ttgatgaacg tgctttccgg
    22801 attattagag ccgacatcag ggaaaatttt gatgcgtggg aaagaagtaa agatcacaag
    22861 tccgaccaaa gccaaccaat tagggattgg gatggtccat cagcacttta tgcttgttga
    22921 tgcctttact gtaacagaaa acatcgtgtt gggaagcgag cctagtcgcg cagggatgct
    22981 tgaccataaa aaagcacgaa aagagatcca aaaagtttct gaacagtatg gattgtcagt
    23041 caacccagat gcttacgttc gtgatatttc agttggaatg gaacaacggg tagaaatttt
    23101 aaaaacactt taccgaggag cagatgtact gatttttgat gagccgacag ctgtattgac
    23161 ccctcaagaa attgatgaat taatcgtgat catgaaggaa ttagtcaaag aaggcaagtc
    23221 gatcattttg attacgcata agttagatga aatcaaagca gtagctgacc gctgtacagt
    23281 tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa gacgtaacct cacaacaatt
    23341 agccgatatg atggttggaa gaacggtttc attcaaaacg atgaaaaaag aagcgaagcc
    23401 tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa gaaaatcgtg gattagaagc
    23461 cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta cttggtatcg ctggaatcga
    23521 tggaaacggg cagtcggagt tgatccaagc tttgactggt ttgcgaaagg cagaaagcgg
    23581 acatatcaag ctaaaagggg aagacatcac taataaaaaa ccccgaaaaa tcactgaaca
    23641 tggtgtagga cacgtgccag aagaccgtca taaatacggg ttagtcctag atatgacatt
    23701 atctgaaaat atcgcactac aaacctatca tcaaaaacct tacagtaaaa acggcatgct
    23761 gaattattca gtaatgaatg aacatgccag agaattgatc gaagaatatg atgttcgaac
    23821 aacgaatgaa cttgttcccg caaaagcttt atcaggcgga aatcagcaaa aagcaattat
    23881 cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt gcaaatccaa ctcgtggact
    23941 ggatgtaggt gcgatcgaat ttattcataa acgtctgatc gaacaaaggg acaaatacaa
    24001 agcagtgtta ctgatcagtt tcgaattaga agaaatttta aatgtttcgg atcgtattgc
    24061 tgttatccat gaaggagaaa ttgtcggtat cgttgatccg aaagaaacat ctgaaaatga
    24121 attaggtcta ttgatggcgg gctatacctt agaagaagca cgaaaagagt tagaaaaggg
    24181 ggctggcgca catgaatgat cgcagcgaaa aattccgtaa tttattagtg cctgtacttt
    24241 cagttgtttt aggattgatc ttaggcgcga tattgatggc tgcttttggt tttcagccca
    24301 tccaaggtta ttcttctatg ctagatgcag cccttggttc gcaaagaggg ataggtgaaa
    24361 cgttaaggca agcaacgccg ttgattttta cagcattagg tttttctgta gctaactcag
    24421 ctgggttttt caatattggg ctttctggac aagcactttg cgggtggatc gtcagtgtct
    24481 gggtggcact tgcgtttcca gatctgccaa aagttgtttt gcttccgtta tgcgtgatct
    24541 taggtgcctt agctggtgcg atggcagcgg ctgttccagg tttacttcga gcattttttg
    24601 gaacaagtga agtgatcgta acaatcatga tgaactatat cttattatac gtaagcacat
    24661 ttgctttaca tgaagtgatg cctgaaagct atcgctcaag tttggactct tccaatatga
    24721 tcagtcaaaa tgcctcactg cggttaccat ggttaacaca agcttttggc ggctctcgcg
    24781 taaactcagg attattttta gcaatcatcg cgcttatttt cgtttggctg ctgatgaaga
    24841 aaacgacttt aggatttgaa atccgttctg ttggattgaa tccttttgct tctgagtatg
    24901 caggaatgag tagtaaacgt acgatcgttt tgtcgatggt catttctggc gctttggcag
    24961 ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa cttctttgtt caaacgactt
    25021 cgctatctat tggatttgac ggaatggctg tttccttgct tggttctgga tcagcaatcg
    25081 gtattctttt atcagcgatc ttgttcagta ttttgaagat cggtggactt ggcatgcaga
    25141 caggagcagg tgttccgttt gagatcgtca atgtatcgat tgctttgatt atcttctttg
    25201 tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt cttccaaggg aaaaaacaag
    25261 aagagatcgt tgcgacaata gaatcgaaac caacgaatca aaaccatgaa gggggcgaac
    25321 tataatgtcg actatcgaat taattgcctt gatccttact tctacactgg tttattcaac
    25381 accgctaatt ctaacgtcac taggcggaac tttttctgaa cgaagcggga tcgtaaacgt
    25441 agggctagag ggaatcatgg tcatgggtgc ttttagttcc atcgttttca acttgacgat
    25501 gagtccatca cttggttcta tgacaccatg gatcgctatt ttagtgggtg gcgtcgtagg
    25561 tatcctattt tctctgattc acgcagtagc aacagtcagt ttgcgtgctg accatattat
    25621 cagcgggaca gtaattaatc tgatggcacc tgctttaggt gttttcttga tcaaagcatg
    25681 gtatggtaaa ggtcaaactg ataacatcac gcagaatctg gggtattttt ctttcccagg
    25741 attagcagat attccggtca ttggaccaat tttctttaaa aatacattct tacctgctta
    25801 ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc ttcaagacga aattcggctt
    25861 gcgcctccgt tcagttggtg aaaatcctca agctgccgac acattaggta tcaatgtata
    25921 tgctatgcgt tattcaggcg tactgatttc tggcttgtta ggcggtatgg gcggtgctgt
    25981 ttttgctcag tcgatttccg gtaacttttc agctggtacg atcgttggac aagggttcat
    26041 ctccatggct gctatgatct ttggtaagtg gaatccttta ggggcaatgg gtgcctcatt
    26101 gttctttggt tttgctcaaa gcttgagtat cattggcgca caattaccag ttatttcttc
    26161 gattccgcca gtattgctgc aaattgctcc atatttgctg acaatcattg tgctggttgt
    26221 tttcttaggg aaagcttctg gtccaaaagc aaacgggaag aactatatca aatcaaaata
    26281 atcttttagc gaataaaaag ggtgggttac gggaagtgtt tttcgtctcg ccctttttgt
    26341 tttaaaggca ataaaaataa aaagaaagaa ggaataatca tgtttaaacg cgtacatctg
    26401 atcgtcatgg attcagtagg aattggagaa gcaccagatg ccgataagtt cggtgatgtt
    26461 ggttctgata cattaggaca cattgcgaaa gaagcaggat tgaacgttcc acatttagag
    26521 cagcttggtt taggaacgat ccgtcctctt gaaggtgtgg aatcagtgaa agatcatcaa
    26581 ggctatgcga cgaaattaga agaagtttct gtagggaaag atacgatgac aggccactgg
    26641 gaaatcatgg gattgaatat caaaactcca tttcgtgtgt ttcctaatgg attccctgat
    26701 gatctgatca aacaaatcga agaattttct ggccgtaaag tcgtatgtaa caaaccttat
    26761 agcggaacag ctgttattga cgattacggt gaacaccaaa tgaaaacagg cgatttaatt
    26821 gtatatactt ctgccgatcc tgtccttcag atcgcggcac atgaagaaat cattccttta
    26881 gaagaattat atcggatttg ccaattcgtt cgtgatataa caaaagatga tccgtatatg
    26941 attggccgaa tcattgcacg tccgtacgtg ggtgaaccag gagacttcac acgaacaagc
    27001 aatcgccatg attatgcgtt gaatccattc ggacacacag tccttgattc tttgaaagaa
    27061 gcaggaaagg acgtgattgc tgttggaaag atcaacgata ttttcaacgg acaaggaatc
    27121 actgaatctg tccgcacgaa aagcaatatg gatggcgttg accagctgct gaaagttatg
    27181 aaaaacgatt tttcaggaat cagctttacc aatttagtag attttgatgc attatacggt
    27241 catcgtcggg atgtagtcgg ctatgcgcat gcgattgaag aatttgactt acgaattcca
    27301 gaattgcttg aagcgatgga agaagacgac ttgctaatga ttacagccga tcacggaaac
    27361 gatccgacgt ttactggtac cgatcatacg cgagaatatg taccgttatt ggtttacagt
    27421 aaaaaaatga aagaacaagg ggcattgcct caaggatatt attcagatat ttcagcaacg
    27481 attgctgaga actttagtgt ttcttcgact gaaaatggcg aaagcttctt gaaattatta
    27541 aaataatctt tttaaatagg agaaagcaaa tgaccaagtt aagcgagatg ttacaagaaa
    27601 cgacccagtt tatccttgat aaaggagtaa aagaaattga ttttggtttg attctaggtt
    27661 caggattagg tgaattagca gatgaaatcg aagatgctgt aatgatttct tatgatgaga
    27721 tcccgttctt tcctgtttcg acagtagttg ggcatgcagg aaagctagtt tatgggtctc
    27781 tggcaggcaa gaaagtgtta gccatgcaag ggagattcca ctactatgaa ggtcattcca
    27841 tgcaaacagt gacctatcca gtacgtgtga tggccggact aggggcccat tcagtcattg
    27901 tgactaatgc atgtggtggt gtcaacgaat catttgtacc aggagatttg atgctgatta
    27961 ccgatcatat caattttact ggtgaaaatc ctttgatcgg tccgaatgaa gatgcaatgg
    28021 gccctagatt tccagatatg agtcaagctt atacgcctga ctatcaagca acagcaaaag
    28081 cagcagcaga aaaactaggt ttggatctta aagaaggcgt atatatgggc tattctggac
    28141 caacttatga aacgcctgcg gagatccgaa tgtctcggac aataggagcc gatgcagtag
    28201 ggatgtcgac tgttccagaa gtcatcgtag cagctcacag cggattaaaa gtgttaggaa
    28261 tctcttgtat taccaactta gcagcaggta tgcaagcgaa tctgagccat gaagaagttg
    28321 tagaaacaac tcagagagtc aaacaatctt ttaaagcatt ggttaaagaa acattgacat
    28381 tattgtaata ggaggaacaa taaaatgagt gtgcatattg aagcgaaaga aggcgagatc
    28441 gccgataaga ttttacttcc gggagatcct ttgcgagcta aatatattgc ggagactttt
    28501 ttggaagatc cagtttgtta caatcaggta cgcggtatgt taggctttac cggcaaatat
    28561 aaaggagaac gtatttctgt tcaaggaaca ggaatgggaa tgccatcagc caccatctat
    28621 gcccatgaat tgatccagtc gtatggtgta aagaaattga ttcgagtagg tacatgcggt
    28681 gcattgtcaa aagacgtcca tgttcgtgat ttagtactag cacaaggtgc agcgaccagt
    28741 tcttcgatga tcgaaaaaaa tttccaagcc tttcattttc ctccaatcag tgatttcaat
    28801 ctattactga aagcatatga gatagctaaa gaaaagggct atacggttca tgtaggaaat
    28861 gttctttcgg aagattcttt ctacaaagat gatttgacag agacgttcca attagctgaa
    28921 cttggcgttt taggagtgga aatggaagca gcggctcttt attacttagg cgcgaaatac
    28981 catgtgcaga cattaagttt gatgaccgtt agcgaccatt tgatcaccgg tgaagaaaca
    29041 acagctgcag aacgtcaatc tacgttcaat gaaatgatcg aagtaggatt ggaaacagcg
    29101 atagcagaat aagaaggaaa tgaaaaagct gccctgcatt aagtaataag aacatccaag
    29161 caaaaatagc tcctcatgtt tttgacttgg ctggacttat tattgcaaat gtaagctttt
    29221 gaacaccgtt taccaagagg ttgtgaatct gccgtttaac tctgagtcac aaggaacaat
    29281 ttcaaaaaac agcttttcat gtttgatgaa tattgtgact tgtgaccgag aagttggcag
    29341 gagaaaaccg tttatacgaa aaaagggact gtgacaaatc gtgtcacagt ccctttttta
    29401 tagtgttttt tataggtagt attttttagc aactgttaag tcatcattta attcataaac
    29461 aagtggttga cctgttggaa tttcaagatc catgatgtct tcgtcagaga taccttcgat
    29521 atgtttagct agggcgcgta atgagttacc atgtgcagct actaaaacag ttttgttgtc
    29581 tagtaatgct ggagcaattt catcttgcca gaatggcaaa gcgcgttcta atgtcacttt
    29641 caagttttct ccaccaggaa tatcgcgttt gtctaacatt gcgtaacgac ggtcatttgc
    29701 tgcagaacct tcgtcagttt cttccattaa tggaggaaga gtatcgtaag aacgacgcca
    29761 gatgtgcact tgttcgtcgc cgtatttttc agctgtttct tttttgttca aaccttgtaa
    29821 tttaccatag tgacgttcgt ttaagcgcca tgatttgatt tgtggtaccc aaagttgatc
    29881 tgaatattct aagatcaagt tacatgtttt gattgcacga gttaaaacag aagtgtaagc
    29941 aacatcaaat tcgattccag cttctttgat tttgcgtccg ccttcttttg cttcttcgat
    30001 tccttctggt gctagattta catcagccca accagtaaat tggttcaatg cattccattc
    30061 actaagaccg tgacgagaaa aaactaattt tggcatgttt agctctcctt ttaagatagg
    30121 tttatatttc tgaaattttc agttctgttt tattgtacaa ttttttggaa gagatttcca
    30181 tcgaaaaatt agataagatt ctatgagaaa acaagtagag aatataaaaa aacgaacagt
    30241 gcccacgcaa ctgttcgttt ttaggtatta gatgcataat tgctcgattt ctttttcagg
    30301 taaattgata tatttataac atgttccaac tgaaacaccg cattttgaag aaataaattg
    30361 gatcgtttct tttttttcat aatagagacg tcggattttt ttgatcgttt ttgcatcgat
    30421 ttttggtctt ccgccgattt ttcctttttt acgagcttca tctaatccaa ctaatgtacg
    30481 ttctttgatc aatgcgcact ccatgtttgc taggttttcc attaattgga aatagatttt
    30541 tcccatttcg cgcgtatcga ttccttcatc aagactaatc aagtgcagcc cgcgatcttt
    30601 gaataattgc gtgagttctg ttaattgccg cgtagatttg cctaatcgat gaagttggca
    30661 aatgactagt gcatcgcctt gttgcatgtc agcgatcact gactccaaat gaacagcagt
    30721 agaatcattt tgttccactt catatgtctc atggaaaatt tcttgacaac caaagtcaga
    30781 taattgatca acctgagttg ttaaatcaac gtcatttatg gttgtgcgtg cataaccaat
    30841 aattttcatg gtgattcctt tctagcagtg attttctaac tggatataac agtaaaaatg
    30901 tagcataaag tacgtcaaaa agatagtttt ttcgcaaatt ttccgctgtc tttttttatt
    30961 ggatgatcaa gcagtttttc tttatttacg acggattgcg tcaagaatct caacgccttt
    31021 ttctgagccg acaactactt tagaaaccat gtttaggaaa agcccatgtt ctactacccc
    31081 aacaagttca tctaaatagg tagctaagct ttctggctgt tcgatgactt ctagatgcag
    31141 atcaatgatg taatgaccac catctgtggt taagacttct ccgttttcgt ctgtacgcaa
    31201 gacgggttgg aatctttttt cttcaaaaat atgaagtagc tgttgggagc cataagggat
    31261 cacttcaact gggagtggga acttcccaag tttatcgact aatttagaag aatcaacgat
    31321 ccaaatcgtt tcttttgagt acgtagcgac tattttctcg aaaagcaaag cagcgccgcc
    31381 gcctttgatc ccttgaaaat cagcactgat ttcatcagca ccgtctattg tcaaatcgac
    31441 tacggggact tcatcaatac tctttaacgg tattcctaat ttttccgctt gttcttttgt
    31501 cgcatttgaa gtagtaactc ctgtgatacg taaaccttct tcacgcatac ggcgaccaat
    31561 ctcttctacc atataatagg cggttgaacc ggtcccgaga cctacgatca tcccgtcctt
    31621 tacgaatttc gcggcttcaa tgccagctaa ttgttttaaa ttcatctttg cgtccacctt
    31681 tttttagttt gagcatcgtg ctttcctcac tattttagcg tgatttacgg taaaaagata
    31741 ccattctttt ttattccaat aaagcttttt caaaaaaaat tgcatctctt gttgacatgt
    31801 tttttcattc gtgatattct aacaaaggtg ctttatctac aggtttctgt gaagaaacgt
    31861 gctgactgtt tatcaaagca tatttgataa ggatgcagac attgcattta ttttttatca
    31921 caaaaaaaga accacctgga tgtgtggaac tagacgcaaa tcgtgggaag gaggaaacaa
    31981 ggaatgccta caattaacca attagtacgt aaacctcgta aatcaaaggt ggaaaaatct
    32041 aattcacctg ctttgaacaa aggatataac agctttaaga aaactcaaac taacgtaaac
    32101 tcacctcaaa aacgtggggt agcaactcgt gtgggtacaa tgacacctaa aaaaccgaac
    32161 tcagctttac gtaaatatgc acgtgttcgt ttgtcaaact taattgaagt tactgcttat
    32221 atcccaggga ttggtcataa cttacaagaa cacagtgttg tattattacg cggtggtcgt
    32281 gtaaaagact taccaggggt acgttaccat atcgttcgcg gtgctttaga tactgctggt
    32341 gttaacgacc gtaaacaaag ccgttctaaa tacggaacta aaaaacctaa agcttaattt
    32401 taattattaa acaaatgaaa cttgcttcta ctatatagaa gtaattacta tgaacaatat
    32461 ttcggaagga ggagttacgg atgccacgta aaggtcctgt tgcaaaacgt gatgttttac
    32521 cagatcctat ttataactca aaattagtaa ctcgcttgat caaccgtgta atggttgacg
    32581 gaaaacgcgg gattgcagct aacattatct ataatgcctt tgacttgatc aaagaatcta
    32641 caggtaacga tccattagaa gtgtttgaac aagcaatgaa aaacgttcaa cctgttcttg
    32701 aagttaaagc acgtcgtgtt gggggttcaa actaccaagt accagttgaa gttcgccctg
    32761 aacgccgcgt tactctaggt cttcgttggg tagtaaacta cgctcgcttg cgcggtgaac
    32821 acacaatgga agaacgctta gcaaaagaaa tcatggatgc tgcaaacaac acaggtgctt
    32881 ctgttaaaaa acgtgaagac actcataaaa tggctgatgc caaccgtgcg tttgctcact
    32941 atcgctggta agattctctc tgtttggtcg gcttttataa gtcgacctca gatagtgtcc
    33001 ttatttttag caactagata gtaaagagag gagaaacaag gagaatgacc agagaatttt
    33061 ctttacaaaa cactcgtaat atcggtatca tggcccacat cgatgctggt aaaacgactg
    33121 ctactgaacg tatcttgtac tatactggta aaatccataa aattggtgaa actcatgaag
    33181 gagcttcaca aatggactgg atggaacaag aacaagaacg tggtattacg atcacttctg
    33241 ctgctactac agcacaatgg aagggtcacc gaatcaacat catcgacaca ccaggacacg
    33301 tagacttcac agttgaagtt gaacgttcat tgcgtgtact tgatggtgct gtaactgttc
    33361 ttgatgcaca atcaggtgtt gaacctcaaa ctgaaacagt ttggcgtcaa gcaacaactt
    33421 atggtgtacc tcgtatcgta tttgcaaaca aaatggacaa gatcggtgct gacttcttat
    33481 attcagtatc aactttacat gaccgtttgc aagcaaacgc tcacccaatc caattaccaa
    33541 ttggtgcgga agacgacttc acaggaatta tcgaccttgt aacaatgaag gctgaaatgt
    33601 atacaaacga tcttggaaca gagatcgaag aaacagaaat tcctgaagaa taccgcgaat
    33661 tagctgaaga atggcgcgaa aaattggttg aagctgtagc tgaaactgat gaagaactta
    33721 ctttgaaata cttagaaggt gaagaaatca ctgaagctga gttaaaagaa ggtatccgcc
    33781 gcgcaacagt taacgtagaa ttctacccag tactatgtgg ttcagcattt aagaacaaag
    33841 gggttcaatt actattggac gctgttcttg attacttgcc atcaccgtta gatatcccag
    33901 ctatcaaagg gattgaccct aaaactgatg aagaagtaga acgtcctgca gacgacagcg
    33961 ctcctttctc agctttagca tttaaagtta tgactgaccc attcgtaggt cgtttaactt
    34021 tcttccgtgt gtactctggt gttttacaat caggttcata cgtacaaaac gcaacaaaag
    34081 gcaaacgtga acgtgttggt cgtatcctac agatgcatgc caactctcgt tcagaaatct
    34141 ctgaagttta cgctggagat atcgctgctg ctgttggttt gaaagacaca actactgggg
    34201 acacactatg tgatgaaaag agtctagtta ttcttgaatc catggaattc ccagaaccag
    34261 ttatccaagt cgctattgaa cctaaatcaa aagctgacca agataaaatg ggtgtggctt
    34321 tacaaaaact atctgaagaa gatcctactt tccgtgctga aacaaacgtg gaaacaggcg
    34381 aaacaatcat cgctggtatg ggtgaacttc acttagatat catcgttgac cgtatgcgtc
    34441 gtgaattcaa agttgaagct aacgtaggtg cgcctcaagt atcttaccgt gaaactttcc
    34501 gtgctggcac tcaagccgaa ggtaagtttg tacgtcagtc tggtggtaaa ggtcaatacg
    34561 gtcacgtatg gattgaattt acaccaaatg aagaaggtgc tggtttcgaa tttgaaaatg
    34621 cgatcgtcgg tggggttgtt cctcgtgaat acattccagc tgttgaaact ggtttgaaag
    34681 atgctatgga aaatggtgtc ttagctggct atccattagt agatatcaaa gctaaacttt
    34741 acgatggttc ataccatgat gtcgattcaa atgaaactgc cttccgtgtt gctgcttcta
    34801 tggcattacg tgcagcagct aagaaagcta atccagtaat ccttgaacca atcatggctg
    34861 tagaagttgt tatccctgaa gattatttag gtgatgttat gggtcacgta actgctcgtc
    34921 gtggacgtgt tgaaggtatg gaagctcgcg ctggcggcca acaagttgtt cgtgcgatgg
    34981 ttccacttgc tgaaatgttt ggttatgcta caactcttcg ttctgctact caaggtcgtg
    35041 gtacatttac aatgacattt gaccactacg aagatgtacc aaaatcagta caagaagaaa
    35101 tcattaagaa aaacggcgga aaagctgaat aatttcttga aaccggatag tcctgcaaag
    35161 agattatcca aagagactat atttttaata tagtttcgtg taaaataatt atcgatgata
    35221 tgggcatgtg gtgtaccttg tgtacatcat atacctatca gacaaataaa aaatatattg
    35281 tatttttagg aggacatttt aaaatggcaa aagaaaaatt tgaccgttct aaaccacacg
    35341 ttaacattgg tactatcgga cacgttgacc atggtaaaac tacattaaca gctgcaatca
    35401 caactgtact atctaagaaa aacggcggcc aagctatggc ttacgatcaa atcgatggtg
    35461 ctccagaaga acgcgaacgc ggaatcacaa tctcaacagc tcacgttgag tatgaaacag
    35521 atacacgcca ctacgctcac gttgactgcc caggacacgc ggattacgtt aaaaacatga
    35581 tcactggtgc tgctcaaatg gacggagcta tcttggtagt ttctgctgct gacggcccaa
    35641 tgcctcaaac tcgtgaacac atcctattgt ctcgtcaagt tggtgttcct tacatcgttg
    35701 tattcttgaa caaagtagac atggttgatg acgaagaatt actagaatta gttgaaatgg
    35761 aagttcgtga cctattaaca gaatacgaat tccctggtga cgatgttcct gtagttgctg
    35821 gatcagcttt gaaagctcta gaaggcgacg cttcatacga agaaaaaatt cttgaattaa
    35881 tggctgcagt tgacgaatac atcccaactc cagaacgtga caacgacaaa ccattcatga
    35941 tgccagttga agacgtgttc tcaattactg gacgtggtac tgttgctaca ggtcgtgttg
    36001 aacgtggaca agttcgcgtt ggtgacgaag ttgaagttgt tggtattgct gaagaaactt
    36061 caaaaacaac agttactggt gttgaaatgt tccgtaaatt gttagactac gctgaagctg
    36121 gagacaacat tggtgcttta ctacgtggtg ttgcacgtga agacatccaa cgtggacaag
    36181 ttttagctaa accaggtaca atcacacctc atacaaaatt ctctgcagaa gtatacgtgt
    36241 tgacaaaaga agaaggtgga cgtcatactc cattcttcac taactaccgt ccacaattct
    36301 acttccgtac aactgacgta acaggtgttg ttgaattacc agaaggaact gaaatggtta
    36361 tgcctggcga caacgtaaca atggaagttg aattaatcca cccaatcgct atcgaaaacg
    36421 gtactaaatt ctcaatccgt gaaggcggac gtacagttgg tgccggtgtc gttacagaaa
    36481 tcaaagctta attcacttaa gttttaaagt aaagcaacat ttattcggac gtaatcgctc
    36541 ggaacgaagg tcttaggatc tttgttccga gcttttttat ttattgcagg atcaggaaaa
    36601 aagacaggag tattataaat agaagaaaca cgaaataaaa gagtcagtat tttctaaatg
    36661 aaactttatg aaaacaaaat gttttttaca agaaaaagcc ttgctttgtg agtttatata
    36721 tattataatg acaaaggtgc gtttacttta gtgaattgca cagacgtaat cagaatgatt
    36781 tcgtcggcta agaaacgaga ggttgcgaca cgcccggacg ctttgccacg aacgagcgtg
    36841 acggaaattt tcgtggagct atgtctactt ttcaaaatag gcgaaggagg gaacaagatg
    36901 gcaaaacaaa aaattcgtat ccgtttaaaa gcgtatgaac accgtatttt agatcaatca
    36961 gcggataaaa tcgtggaaac tgcaaaaaga actggagcta gcgtgtctgg tccaattcca
    37021 ttaccaactg aacgcagtct ttacacaatc atccgtgcga ctcataaata caaagattca
    37081 cgcgaacaat tcgaaatgcg tacacacaaa cgtcttatcg acattgtgaa cccaacacca
    37141 aaaactgttg atgctttgat gaagctagac ttaccatctg gtgtaaacat cgaaatcaaa
    37201 ttataaaact aaaacaaaaa taatggaggt gtactcatga ccaaaggaat cttagggaaa
    37261 aaagtgggaa tgacacaaat cttcactgaa tctggtgaat taattccagt aactgttgta
    37321 gaagctactc caaacgtagt actacaagtg aaaacaatgg aaacggatgg ctacgaagct
    37381 attcaagttg gttaccaaga tatgcgtgaa gttttatcaa acaaacctgc gaaaggtcat
    37441 gttgcaaaag caaacacggc tcctaagcgc ttcattcgtg aattcaaaaa tgttgagcta
    37501 ggagaatatg aagtaggaaa agaaattaca gtagatgttt tccaagcagg agacattatt
    37561 gatgtaacag gtactacgaa aggtaaagga ttccaagggg ttatcaaacg ccacggacaa
    37621 agccgcggac caatggctca cggttctcgt taccatcgtc gtcctgggtc aatgggtcca
    37681 gttgcaccta accgtgtatt taaaaacaaa cgtcttgctg gccgtatggg tggcaaccgc
    37741 gtaactatcc aaaacttgga agttgtacgt gtcgatgcag aaagaaatgt tatcttgatc
    37801 aaaggtaatg ttcctggagc taaaaaatct ttaattacta tcaaatcagc tgtgaaagct
    37861 aaataattgt aggaagaaag gaggaactaa ggaatgccga atgtagcatt attcaaacaa
    37921 gatggaagcc aaaacggtga aatcacactt aacgaagaaa tcttcggaat tgaacctaat
    37981 gaaagtgttg tttacgatgc aatcgtaatg caacgtgcgt cattaagaca aggaacacac
    38041 gcggttaaaa accgtagcgc tgttcgcggc ggcggacgta aaccatggcg tcaaaaagga
    38101 acaggtcgtg cacgtcaagg atctatccgc tcaccacaat ggcgtggagg tggcgtagtc
    38161 tttggaccaa caccacgttc ttacagctac aaacttccta aaaaagttcg tcgtttagca
    38221 atgaaatctg tattgtcaga aaaagttgct gaaaacaact tggtagcaat cgaaggcttg
    38281 aacttcgacg caccaaaaac aaaagaattc aaacaagttc ttgctaactt atctatcgac
    38341 tctaaagtat tggttgttct agaaaaaggt aacgactttg ctgctttatc agcacgtaac
    38401 ttaccaaacg tttctgtagt aacttctgat aatgtgagtg tgctagacgt tgtatcaaat
    38461 acaaaagtgt tagcaacaca aactgctctt actcaaattg aggaggtgct tgcataatga
    38521 acttactaga cgtaatcaaa cgcccagtga tcactgaaaa atcaatgctt gccatggatg
    38581 acaagaaata cacttttgaa gtggacactc gcgcaaacaa aactttagta aaacaagcgg
    38641 tagaagctgc ttttgacgtt aaagtcaaaa acgtgaacat cgtgaacgta cgtgcgaaat
    38701 tcaaacgtat gggcaaatat gcaggatata caaaaaaacg tcgcaaagcg atcgttacat
    38761 tgactgaaga ttcaaaagaa atccaattat tcgaagctgc tgaataagca ctaatagata
    38821 actcattaaa ttaggaggga aaaacgtggc gattaaaaag tacaaaccta cctcaaatgg
    38881 tcgtcgtaac atgacaggtt ctgattttgc tgaaatcaca acatcaacac ctgaaaaatc
    38941 attgttacaa ccattgaaaa accatgctgg acgtaacaac aacggccgca tcactgtacg
    39001 tcatcaaggt ggcggacaca aacgccaata tcgcgtgatc gacttcaaac gtaacaaaga
    39061 taacgttgtt gcaactgttc aaacgatcga atatgatcca aaccgttcag ctaacatcgc
    39121 gttagtacac tatgaagatg gagtgaaagc ttacatctta gcacctaaag gactagaagt
    39181 gggtatgaaa cttgtttcag gtccagaagc agatatcaaa gtcggaaatg ctcttccatt
    39241 agaaaacatt ccagttggta ctgttatcca caacattgaa atgaaacctg gtaaaggtgg
    39301 acaattgatc cgttctgctg gtacaagtgc tcaagtactt ggtaaagaag gcaaatacgt
    39361 attgatccgc ttgaactctg gtgaagttcg tatgatctta gctgcatgcc gtgctacaat
    39421 cggttctgta ggtaacgaac aacacgaatt aatcaacatc ggtaaagctg gacgctctcg
    39481 ttggatgcgt aaacgcccaa ctgtacgtgg tagcgtaatg aaccctaatg atcacccaca
    39541 cggtggtggt gaaggtaaag ctcctatcgg acgtaaagca ccagtttctc cttggggtca
    39601 accagctctt ggttacaaaa ctcgtaacaa aaaagctaaa tcagacaaac ttattgttcg
    39661 tcgtcgcaaa aataaataat tactttgacc atgtgtcgca cattttgaga ggaggttcac
    39721 catgggtcgt agtttaaaga aaggaccttt tgtcgatgag catttaatga aaaaagttga
    39781 agctcaagca ggggttgaaa agaaaaaagt tatcaaaact tggtcacgcc gttcaacagt
    39841 tttcccaagt tttgttggat ataccatcgc agtttatgat ggacgtaaac atgtaccagt
    39901 ttacatccaa gaagacatgg taggacacaa attaggtgaa tttgcaccta caagaactta
    39961 tcgtggacat gctgctgacg ataagaaaac gaaacgctaa tttgagggga ggataaatcc
    40021 aaatggcaga acaaatcaca tcagctaaag caactgcaaa aacagttcgc acttcacctc
    40081 gaaaagcccg tttagtaatt gaccttatca gaggtaaaag tgtcgcagat gcaatttcaa
    40141 tcttgaaatt cacaccaaac aaatctgctg gaatcattga aaaagtattg atgtcagcag
    40201 ttgcgaatgc agaaaataac tttgacttag atgttgaaaa cttggtagta agcgaagctt
    40261 ttgttaacga aggacctaca atgaaacgtt tccgtcctcg tgcaaaagga tcagcttctc
    40321 caatcaacaa acgtacaagt catatcacgg tagtcgtatc agaaaaataa ggagggataa
    40381 tcagtgggtc aaaaagtaca tccaattgga atgcgtgtag gcatcatccg cgactgggat
    40441 gctaaatggt atgctgaaaa agagtatgct gagttcttac acgaagattt aagaatccgt
    40501 aaatttattt caactaaact tgctgatgct gctgtatcaa cagttgaaat cgaacgcgca
    40561 acaggtcgcg taaacatttc aattcacaca gctaaaccag gtatggttat tggtaaaggc
    40621 ggttctgaag tcgaaagcct aagaaaagaa ttaaacaaat taactggtaa aagaatccat
    40681 atcaatatcg tggaaatcaa aaaaccagat ctagatgcaa aattagtagg tgaaggaatc
    40741 gcacgtcaat tagaaaaccg tgttgctttc cgtcgcgctc aaaaacaagc catccaacgc
    40801 tcaatgcgtg ctggcgctca agggatcaaa actcaagtat ctggtcgtct aaacggagca
    40861 gatatcgctc gttcagaagg atactcagaa ggaactgttc ctcttcatac tttacgtgcg
    40921 gacattgatt acgcatggga agaagcagat acaacatacg gaaaactagg agttaaagtg
    40981 tggatctatc gtggagaaat tcttccaact aaaaaaaaca ctgagaaagg agggaaataa
    41041 tcatgttagt acctaaacgt gtaaaacacc gtcgtgaatt ccgcggaaaa atgcgcgggg
    41101 aagctaaagg cggaaaagaa gtagcattcg gtgaatacgg tttgcaagct gttgattcac
    41161 attggatcac aaaccgccaa atcgaagctg ctcgtatcgc aatgactcgt tacatgaaac
    41221 gtggtgggaa agtatggatt aaaattttcc ctcacaaatc ttatactgcc aaagcaattg
    41281 gggtacgtat gggttctggt aaaggggcac ctgaaggatg ggttgcacca gtaaaacgtg
    41341 gtaaaatcat gtttgaaatc gcaggcgttc ctgaagaagt agctcgtgaa gcgttacgtc
    41401 tagcttctca caaattacca atgaaaacta agatcgtaaa acgtgaggaa atgggtggtg
    41461 aatcgaatga aggttaaaga aatcagagaa ttaaccactg ccgaaatgct tgatcaagaa
    41521 aaacaattaa aagaagaatt gtttaatctt agattccaat tagcaacagg tcaattagaa
    41581 aacactgcac gtattaaaga agtacgtaaa tcgattgcac gcatcaaaac tgtgttgcgt
    41641 gaacaagcta agtaattatg gaaggaggcc attaagcgta tgactgaagg aagaaatcaa
    41701 cgcaaagttt atcaaggtcg cgtggtttca gacaaaatgg ataaaacaat taccgttgct
    41761 gtcgaaacaa agaaaaacca ccctatctat ggcaaacgca tgaactattc taagaaatac
    41821 aaagtgcatg atgaaaacaa cacagcaaaa gttggcgaca tcgtgagaat tatggaaact
    41881 cgtccattat cagctacaaa acgtttccgt ttgttggaag tagtcgaaga agcagttatt
    41941 atctaataac acgagatttt cctatataga ttgaatgcaa aatctgaaag gaggatacac
    42001 aacgtgatcc aagcagaaag tcgtttaaaa gtcgctgata actcaggcgc acgtgaaatt
    42061 ttgacgatca aagtccttgg tggatctggt cgtaaaactg ctaacatcgg tgatgtgatc
    42121 gttgctacgg ttaaacaagc aacgccaggt ggggttgtca aaaaaggtga cgtcgttaaa
    42181 gccgttatcg ttcgaacaaa atcaggagct cgtcgtacag acggttcata tattaaattt
    42241 gatgaaaatg ctgcagtgat tattcgtgat gataaaagcc ctcgtggaac acgtatcttt
    42301 gggccagttg cacgtgaact acgtgaaaac aacttcatga agatcgtttc actagcacca
    42361 gaagttttat aatcttgaga cacttatcaa aggaggtgcg aaacagttat gtttgttaaa
    42421 aaaggcgata aagttaaagt tatcactgga aaagacaaaa acaaagaagg cgttgtacta
    42481 gcagcgttcc cgaaaaaaga taaagttatt gtcgaaggtg taaatgtcgt taaaaaacac
    42541 caaaaacctt ctcaagctgc tcctcaaggt ggaattgttg agatggaagc gccaattcat
    42601 gtttctaacg tgatggtggt tgactctact ggtgtagctg gccgagttgg ctacaaagaa
    42661 gtagacggca aaaaagtccg tgtttctaaa aaaaccggtg aagttttaga taaataaaag
    42721 tttaaggaag gagggtctta ctgaatgaac cgcctaaaag aaaaatatct taaagaagta
    42781 actccatcat tgatggaaaa atttaactat agctctgtta tgcaaacacc taaagttgaa
    42841 aaaatcgtca tcaacatggg tgttggtgat gcggtatcaa acgctaaaaa cttagataaa
    42901 gcagttgaag aattaacttt gatcactggt caaaaaccaa tgattacaaa agctaaaaaa
    42961 tcaatcgctg gattccgttt acgtgaagga atgccaattg gtgcaaaagt tacattgcgc
    43021 ggagaaagaa tgtacgaatt cttagacaaa ttggtttctg tttcactacc acgtgtacgt
    43081 gacttccatg gtgtaagtaa aaaagccttt gacggtcgtg gaaactatac tttaggtatt
    43141 aaagaacaat tgatcttccc agaagtagat tatgatttag tagataaagt acgtggtatg
    43201 gacatcgtta ttgtaacaac agcaaactct gatgaagaat ctcgtgagtt gttgacacaa
    43261 ttaggcatgc cattccaaaa ataattaaag gaggcgaact acgtggctaa aaaatcaatg
    43321 attgctaaaa acaaacgtcc tgcaaaattt tcaacacaag cttatactcg ttgcgaacgt
    43381 tgcggacgtc cacattcagt ttatcgtaag ttccatcttt gccgtatttg cttccgcgaa
    43441 cttgcctata aaggtcaaat tcccggcgtg aagaaagcta gctggtaaaa agtaaattcg
    43501 cataagaagg aggtaaaaga tcaatggtca tgacagatcc aattgcagat tttctaactc
    43561 gtatccgtaa cgcaaacatg gttaaacatg agtctttaga agtacctgca tcaaaaatta
    43621 aacgtgacat cgctgaaatc ttgaaacgtg aaggtttcgt tcgtgatgtt gaatacatcg
    43681 aagatgacaa acaaggcgtg atccgtgttt tcctaaaatt tggtaaaaac ggcgaacgtg
    43741 ttatcacaaa cttaaaacgt atctctaaac caggtttgcg tgcttatgtc aaagctgacg
    43801 aagtaccaaa agtattgaac ggtttaggta tcgcaatcat ttcgacttct gaaggtgttg
    43861 tcactgataa agaagctcgt gaaaaaaata tcggcggcga agttatcgct tacgtatggt
    43921 aatcaagtag aatctacaag gaggtgtctt taagtgagcc gtatcggaaa taaagtcgtt
    43981 gttatccctg aaggagtaac agttactcaa gacggaaaca acgttacagt taaaggacca
    44041 aaaggtgaat tgactcgtac tttttcagca gatatcaaaa tgaatatcga aggaaacgaa
    44101 gtaactttca ctcgtccaaa cgacagtaaa gaaatgaaaa caattcatgg aacaactcgt
    44161 gcgaacttca acaacatggt tgtaggtgtc agcgaaggtt tccaaaaagc gttagaacta
    44221 atcggggttg ggtaccgtgc acaattacaa ggatcaaaac ttgtattgaa cgttggttac
    44281 tcacatccag tagaaatcac accaccagct ggagtaactg ttgaagtacc agctaacaca
    44341 caagtaattg ttaaaggtgc gaacaaagaa gaagttggcg aattagctgc aaacattcgt
    44401 ggaactcgtc ctccagaacc ttataaaggt aaaggtattc gttatgttgg cgaatatgta
    44461 cgccgtaaag aaggtaaaac tggtaaataa tcgtttagaa aaattgcata gaagccagca
    44521 gcaggaaaaa ggcatttggc tgaagtttac cttcaaaaaa atacattttt acttgtgccg
    44581 cagcttctat ttttcgaaac gtatttactg cttgaaatag tagtacaata aaaataaaga
    44641 ggtgacaatt gtgattacaa aaccagataa gaacaaaaca cgtcaaaaga gacatcgtcg
    44701 tgtacgtaac aatatctctg gtactgctga gcgcccacgc ttgaacgttt ttcgttctaa
    44761 caaaaacatc tacgctcaaa ttattgatga cgtagcgggt gtaacgctag caagtgcctc
    44821 taccttggat aaagaaattt caggtggaac aaaaacagaa gcagcacaag ctgtcggtaa
    44881 actagttgct gaacgtgcag ctgaaaaagg cattaaagta gtagtctttg accgtggtgg
    44941 atacctttac catggccgtg tgcaagcttt agctgaagct gctcgcgaaa atggactaga
    45001 attttagaag aaggaggaat accattcatg gtttatatcg atccaaaaca tttggaatta
    45061 gaagaccgcg ttgttgcaat taaccgtgta acaaaagttg ttaaaggtgg acgtcgtcta
    45121 cgttttgctg ctttagttgt tgtcggtgac aaaaacggac acgtaggatt tggtacaggt
    45181 aaagctcaag aagttcctga agcaatccgt aaagcaattg aagatgcgaa gaaaaactta
    45241 gttgaagtac ctatggttgg ttcaacaatc ccacacgaag taatcggtgc ttttagtggt
    45301 ggtagaatcc taatgaaacc tgctgtagaa ggttctgggg ttgctgctgg tggaccagtt
    45361 cgtgccgtat tagaattagc tggggtagca gatatcactt ctaaatcttt aggctcaaat
    45421 acaccaatca acgttgttcg cgcaacagtt gaaggtttga aacaattgaa acgtgcagaa
    45481 gaagttgcag aacttcgcgg caaatcagtt gaagaattaa tcggataagg aggacaacaa
    45541 taatggctga attaaaagtt actttaaaac gcagtattat cggacgtcct caaaaccaac
    45601 gcgatacagt taaagcgtta ggtcttacaa agattaacag ttcagtggtt aagccttcta
    45661 atgaagcaat taaaggcatg atcaatactg tttctcacct agtggacgtt gaagaaattt
    45721 aatttagaaa aatcataact agaacattaa ggaggtgcca aacctatgaa acttcatgaa
    45781 ttaaaacctg ctgaaggttc acgccaagta cgtaaccgtg ttggtcgtgg tacttcatct
    45841 ggtaacggaa aaactgccgg acgcggacaa aaaggacaaa aagctcgttc aggcggcggt
    45901 gtgcgtttag gatttgaagg gggacaaaca ccattgttcc gtcgtttacc aaaacgagga
    45961 ttcacaaacg tgaaccgtaa agactatgca gtcattaatc ttgatgtatt gaaccgcttt
    46021 gaagacggag ctgaagtaac tcctgttgct ttagttgaag ctggaatcgt gaaaaacgaa
    46081 aaagctggaa tcaaagtatt agctaatggg gaactaaaca agaaattaac tgtgaaagca
    46141 gcaaaattct ctaaagcagc tcaagaagca attgaagcgg ctggtggatc aatcgaggtg
    46201 atctaatgtt tagactatta aaagatgctt ttaaagtaaa agacattaga tcgaaaatcc
    46261 tatttactgt atttgtgttg tttgtatttc gcctaggtgc acatattact gtaccaggcg
    46321 taaatgctgc ttcattgcaa aacctttctt ctttgccatt tttcaacatg ttgaacttgg
    46381 taagtggtag tgcgatgcaa aacttttcca ttttctcaat gggggtttca ccatacatta
    46441 ctgcttctat cgtcattcag cttcttcaaa tggacatcgt gcctcgattt gttgaatggt
    46501 cgaaacaagg ggaagttggt cgtaaaaaac tgaatcaagc gactcgatat ctgacattag
    46561 tattggcatt tatccaatct gtcggtatca ctgctggatt caatcaatac gctcaattag
    46621 gtttcgtgaa taatcctaac gtagcaactt acgtaacgat cggtttgatt ctaacagccg
    46681 gtacgatgtt tgttacttgg ctaggagaac agatcacaga aaaaggtatc ggaaatggcg
    46741 tatcaatgat catttttgca ggtatcattt ctagattgcc tgaaagtatc agagaaattt
    46801 atgaagatta ctttataaat attgatcctt cagacatatg gaaatctgct atttttgtgg
    46861 ccattttact agtagcggtc ttgttgatcg tgacattcgt aacatttttc caacaagctg
    46921 aacgcaagat cccgatccaa tatacgaaac gcgtagctgg cgcgcctaca agcagctatc
    46981 tgccgttgaa agtaaatgca gctggagtta ttccagttat ctttgctagt tcgtttattg
    47041 ctacgccaaa tgctgtttta caagcattga gcggtagatt cggttctgaa aactggtaca
    47101 aagtgatgat ggagatcttt aactataata cagcacctgg tgctacgatt tatacgattc
    47161 tgatcgttgc cttcactttc ttctacgcct ttgttcaagt aaaccctgag aaattagcgg
    47221 aaaacttgca aaagcaagga agttatatac caagcgtacg ccctggtaag gggactgaag
    47281 agtatgtctc aagattactg atgcgtttaa gtacagttgg tgcagtcttc cttggtttag
    47341 tggcattgct tccaatcatt gctcaaatgg tttgggatct tccacaatca atcggattag
    47401 gcggtacaag cttactgatc gttatcggtg tagctttaga aactgcgaaa cagttagaag
    47461 gcttaatgct gaaacgtaaa tatgttggat tcattgagta agaaagcgtg ttgaggtttc
    47521 ccctcaacac acgttctcac acatttatta ggagggaaaa caatgaacct cattttaatg
    47581 gggctgccag gcgcaggtaa aggaacacaa gctgaaaaaa tcattgatgc ttatggtatt
    47641 ccgcacatct caacaggaga tatgttccgc gcagcgatgc aaaacgaaac agctcttggc
    47701 ctggaagcaa agtcttatat ggataaaggt gcattagttc ctgatgaagt aacaaatgga
    47761 atcgtgaaag agcgactagc tgaaccagat acagagaaag gcttcttatt agatggcttt
    47821 ccacgtacgc tagatcaagc aaaagctctg gacgcaatgc taaaagattt gaataaaaaa
    47881 attgatgctg tcatcgatat ccatgttggt gaagaaatct tggtcgaacg tctagccggc
    47941 cgatttatct gcagcaattg tggagcaact taccataaaa ttttcaaccc tacaaaagtt
    48001 gaagacacat gtgatcgttg cggtgggcat gaattctatc aaagagaaga tgataaacct
    48061 gagacggtta aaaatcgtct ggctatcaac atcaaaaata gtgaaccaat cttggcttat
    48121 tataaagaac aaggtttgct aaacactatt gatggtgctc gtgaaatcga tgctgtattt
    48181 gcagatgtac aaaaaatcat tgaaaaatag cacgattgcc cgtagccgac ttgcattatg
    48241 cagttactct tgtcaagttc aataaattat gatagaatat gtcagtccga cttctagaga
    48301 atcctctaga tgatccattt tgagaatttt gaggtgggaa ctgcagtttc cgccatttta
    48361 tcgtgtgaaa atgcgaaaca agtacaagga ggtactgtgc gtggcaaaag aagatatgat
    48421 tgaagtcgaa ggtacagtcg tcgaaacttt gccgaatgca atgtttaaag ttgaactaga
    48481 aaacggacac caagttcttg ctactgtttc aggtaaaatt cgtatgcatt acatccgtat
    48541 cttacctggt gacaaagtaa cggttgaatt gtctccatac gatcttaacc gtggccgtat
    48601 tacttatcgc tttaaataat tgtactccgt aaaactacag gaggtattat catgaaagta
    48661 agaccatcag taaaaccaat gtgcgaacat tgtaaagtaa ttcgtcgtaa aggacgcgtt
    48721 atggtgattt gcccagcaaa tccaaaacat aaacaacgtc aaggataatt ggaggtgcta
    48781 taaatatggc tcgtattgca ggagtagata ttcctcgtga taaacgtgta gtagtttcac
    48841 ttacttatat ctatggtatt ggtaacacta ctgctaaaaa gatcttagct gatgctggtg
    48901 tatctgaaga tgttcgcgtt cgtgaattaa cgaatgaaca aacagatgct atccgtgcag
    48961 aagtagataa attaaaagtt gaaggggatc ttcgtcgtga agtgaacttg aacatcaaac
    49021 gtttgatgga aatcggttct taccgtggaa tccgtcatcg ccgtggattg cctgttcgtg
    49081 gacaaaacac gaaaaacaat gcacgtactc gtaaaggccc agctcgcgct atcgctggca
    49141 agaaaaaata attcttaagt gaaggaggtt aaaacttcat ggcagcaaaa aaagtgaatc
    49201 gtaaacgccg tgtgaagaag aatatagaag caggtattgc acatatccat tctacattca
    49261 ataacactat catcatgatc actgatactc acggaaatgc attagcgtgg tcatcagctg
    49321 gttcattagg tttcaaagga agcaaaaaat caactccttt tgccgctcaa atggcagcag
    49381 aaactgctac aaaagcagca atggaacacg gattaaagac tgttgaagta acagttaaag
    49441 gacctggttc tggacgtgaa gcagcaattc gttcattaca agctacaggt ttagaagtga
    49501 ctgcaattcg tgacgtgact ccagttcctc ataatggtgc ccgccctcca aaacgccgtc
    49561 gtgtttaatg agtgccgctc attttgagtt ttatcagtaa cgtcattgaa caagacactt
    49621 ttcgttttga aaggggtaaa gataagaatg attgagttcg aaaaaccaag aatcgcaaaa
    49681 attgatgaag aaaaagatta tggcaagttc atcgttgaac ctcttgaaag agggtatggg
    49741 actactttag ggaattccct acgtcgtatt ttattatctt ctttgccagg tgctgccatc
    49801 actaatattc aaatcgatgg tgtactgcat gaattctcta ccatcaaagg tgttagagaa
    49861 gacgtcactc aaatcatctt gaacattaaa ggcttagcgc tgaaaatgta tggccaagaa
    49921 gaaaaaaccc ttgaaatcga tattaccgga cctgctacag taactgctgg cgatattatc
    49981 gttgatagtg atgtagaaat tcttaacaaa gatatgtaca tctgtagtgt ctctgaagga
    50041 gctacgttcc atgctcgctt aacagtgaaa cctggacgtg gttatgttca agcagatgaa
    50101 aataaaaaag aagatatgcc aattggcgtt cttccagtcg attcaatcta cacacctgtt
    50161 cgtcgtgtga actatcaagt tgagaacaca cgtgttggac accgtgaaga ttttgataaa
    50221 ttgacgatgg agatttggac agatggttca attgaaccgt tggaagcaat gagtttgtct
    50281 gcgaaaatca tgactgaaca tttggatatt tttgtgaact taactgatga agcaaaaaat
    50341 gctgaaatca tggtcgaaaa agaagaaaca caaaaagaaa aaatgttgga aatgacgatc
    50401 gaagagttag acttgtctgt tcgctcttac aattgtttga aacgtgcagg aatcaatact
    50461 gtacaagaac ttacaaataa atctgagcct gaaatgatca aagtccgtaa cttaggacgt
    50521 aaatcattag aagaagttaa agcaaaattg cacgacttag gtttaggttt acgtaaagaa
    50581 gattaaaacc ttttacgaag gagggaaacc aacgtgagtt atcgtaaact aggacgcaca
    50641 tctagccaac gtaaagcgat gttgcgtgat ttaacaactg atttattaat caacgaacgt
    50701 attgtgacta ctgaagctcg tgcgaaagaa gttcgctcaa ctgcagaaaa aatgatcact
    50761 ttaggtaaac gcggagattt gcatgcacgt cgtcaagctg cggctttcgt acgtaatgaa
    50821 gttgccagcg tgcgtgaaga aaatgaggac atcgtcattg aatcagcttt acaaaaactg
    50881 ttcaacgata ttgcacctcg ttacgcagaa cgtcaaggcg gatacacacg cattttgaag
    50941 acagaaccaa gacgcggtga tggtgcacca atggttgtct tagaacttgt ctaaaatcac
    51001 actaataaca tcactttata gatgattctt ttagagtgtt atgatgttgg aagatatttt
    51061 tccgagtcta gctcagcgct gctcctcaag cgaatatcgc ttggggagta agcactcatc
    51121 ataaagtgtt tttttatacc ttcaattacc tgtcatgaca gatatgtttg aaggcataaa
    51181 aaaacatttt aagcgagaaa taattgaaaa ttttgtcttt ttttgatagt gttagtagga
    51241 actttaggat gaagaaggag taatcatgga gccaattatt gaattagaaa agataaatta
    51301 taaataccag ccagatgatc ttcgccccgc attgaaagat gtctccttta caattgataa
    51361 aggtgagtgg atcgctatta ttggacacaa tggttcagga aaatcgacac ttgccaaaac
    51421 gatcaatgga ttgcttctgc cagaatcagg gatcgtgaaa gtgggaaatc aaatattgga
    51481 tgaagaaaat atttggacga tccgacagat ggttggaatg gtttttcaaa atccagacaa
    51541 tcagtttgtt ggttcgacag tagaagatga cgttgctttt ggtcttgaaa atcaagggat
    51601 tcccagagaa gaaatgctag tgcgtgtgaa agatgcactt gagaaagtta gaatggctga
    51661 gtttgcttca cgcgagcctg ctcgtttatc aggagggcaa aaacaacgtg ttgccattgc
    51721 cggcgtggtt gccttacgac ctgatatcat tattttagat gaagcaacca gtatgctaga
    51781 tccagaaggt cgtgaagaag tgatctctac gatcaagaag atcaaagaag aaagtcaatt
    51841 gaccgttata tctatcactc atgatattga tgaagcagct aatgccaatc ggatactagt
    51901 gatgagacaa ggcgaacttg tccgtgaagg tacaccaaaa gaaatttttt ctgctggtcc
    51961 tgaactgatc gacttaggtc tagatctacc atttcctgaa aaactgaaga gcgcactgaa
    52021 agaacgtggg gttgatgtgc ccagtgaata tatgacagaa gaaaggatgg tggattggtt
    52081 atggacatcc gttttgaaca agtagacttc acttatcagc cgaatacacc atttgaacaa
    52141 agagccttat ttgacatcaa tatgacgatc aaagaaaaca gttatactgc attagtaggg
    52201 cataccggaa gcgggaaatc aaccttactt cagcatttga atgcgcttgt taagccaaca
    52261 agcggtacag tccatattgg agaacgagat attcagccgg atacggataa taagaattta
    52321 aagcccatcc gaaaaaaagt tggcatcgtc tttcagtttc cagaagcaca gctattcgaa
    52381 gaaacggtag caaaagacat tgctttcggt cctaaaaact ttggtgtcag cgaagaagaa
    52441 gcactagtcc tagcaaaaga aacattagaa caagttgggc tggatgaaag ctatttggaa
    52501 cgttcgccat ttgaactttc aggagggcaa atgcgtagag tagcaatcgc tggtgtgctt
    52561 gccatgaggc cggaagtact tgtattggat gaaccaacgg caggacttga tccccagggc
    52621 agaaaagaaa tgatggagat gttttggcgt cttcataagg aacagcagat cactattgta
    52681 ttagttacgc atttaatgga tgatgtagcc aattttgcag attatgtcta tgtgttggaa
    52741 aagggacgaa tcgttaatag cggggagccg caagaggtct ttcaaaacat tgaatggcta
    52801 aaagaaaaac aactaggcgt acctactgcc accgagtttg cagaagaatt aatggctaaa
    52861 gggatgaact ttgctacctt gcctttgaca gctgaagaat tagcagacgc tatcgtccat
    52921 tatgctggag gaaatgccca tgatgaataa attgatattt ggtcgttata tgcctggaga
    52981 ttccttgatc catcgattgg atccccgagc taaattatta gccagttttt attttatcgg
    53041 aatcattttt ttagcaaata attgggaaac gtaccttttg ttggcatttt tcacattact
    53101 ttctgtcttc ttgtcaaaag tagatttgaa attttttatc cgaggcattc gcccattgat
    53161 ctggctaatc ctcttcactg tagctttgca ggtcttgttt acaagtggcg gagaaactta
    53221 ttggagttgg ggtgttttcc atatcactga atttggtgtg atgaacggcc tctttatttt
    53281 ctgtcgattc gtgttgatca tttttatgtc gactctactc acgcttacta caccgccttt
    53341 ggaattatcg gatgcgattg agtacttgct tcgtccattg aaagccgtac ggttcccagt
    53401 ccacgaaatt tcattgatgc tgtcgattgc tcttcgtttt gtgcctacat tgatggacga
    53461 aacagaaaag atcatgaacg ctcagcgcgc tcgcggtgtt gattttggtg aaggaaacct
    53521 agttcagaaa atgaaagcag tcattccttt gctgattcct ttatttgtca gcagcttcaa
    53581 ccgtgcggaa gatcttgcga ctgctatgga agcaagaggc tacaaaggtg gggaaggaag
    53641 aacgaaatat cgtgtattgc attggcataa tagagacacg atggttatca ttgcttttgt
    53701 attattaact gtgctactga tctttttaag aggataaacg ttcagtgggc cgctatctat
    53761 tcttttcttg ctgatctgtt tgcaagaaag gatgcaagca gtgtatgaca agaaatatta
    53821 gggtctgtgg cagactaagg tcacaggcct ctttctttta tctgaaaaga aagaacgaaa
    53881 aaattttata gaaaaatcat tattccagat aaccttttag gaacaaagga gagaaaaaca
    53941 tggtacgtta caaagcaatc attgcgtacg acggaacaaa ttttaatgga ttccaaaaac
    54001 agccaaatgg gcgtactgtt caagaagaag tagaaaaaac attacaaaaa atggcaaatg
    54061 gaaaagaaat cacggtcttt ggttcgggaa ggacagatgc cggagtacat gcgatcgggc
    54121 aagtaatcca ttttgattat ccagaggagc gtccgttaga acgaatgcgt ttcgcgctag
    54181 atacccagtc accagaggat attgctgtaa gacaagtaga aattgtttca gaagacttcc
    54241 acgcaagata tttggtcaaa gaaaagacgt atcaatttcg agtggatata gggaaaccac
    54301 gcagtccttt tcgacgccat tatgcaagtt attttcctta cccacttgat ttggaaaaaa
    54361 ttcagcgggc gcttcctgat ttattaggga ctcacgattt cacctctttt tgtgcatcag
    54421 gaagctcgat agaggataaa atacgtacga tctacgaggc taagatggag gtaaatgaaa
    54481 caaaagacga attgttgttt acatttaggg gaaatggctt cttgtataag atgatacgga
    54541 tcttagtagg aacgcttttg aaaattggca atggccgatt gcctgaagat agtatcccag
    54601 atattattgc gaaaaaagat cgtaatgcag caggacctac agcacaccct gaaggacttt
    54661 atttgtatga agtgaaatat gaataagagg ttatgataga agtggtcagc ttcaagaaat
    54721 aagaaggtat ttacgaaaat tacttctcaa aattttgcaa aatttcggct tattttcgaa
    54781 gaagctactt ctggaacacc gtttaaggaa gaggtcgtga aatcagcgtt ttgacctgag
    54841 tattagagaa acaaacggga aaatagctcc tcatattttg ccgtttgttg agctaatacc
    54901 gaaggtcagc tgattgaaca ccgtttaaga aagaggtcgt gagcctgtca tttaactctg
    54961 agtcacaaag agcaatttca aaaaacagct tctcatcttt gatgaatatc gtgacttgtg
    55021 gacgaggcgt tgataagtga atcatctttt tgttacctat tttttctgta accaaaaaac
    55081 gatggaacgt tgttttgatt gcccttggtg cggacagtct gaacaggttc catcgtttct
    55141 ttattttcta cgtcttcttc tgtgtgtgtt tcgtggttgt tcttctattg ctggatcaat
    55201 cgtgccataa aaggggcgat tgcggtcaag gtaccagaca taaagaataa acaatgcaat
    55261 acataggaca aaaaggattg cacctatcgt aaatccttca ggcaagtaac tgaaagtgac
    55321 agtatgttta cctgctggaa cttttatcat caagaatgcg tctttgaaat tgctgacctt
    55381 gactggtttc ccatcaattt tagctttcca tcctttgtca taaggaatag ttgtcaccaa
    55441 catggaatct tcagcggtat ttacagtccc agaagctttt ctgccagtgg cttccatttc
    55501 gacacctttt tctttgatct gattcattgc ggcttgatag gctacaacat ctagaccaac
    55561 gactttaggc tccatgaaac ttatttcttt cgtcccataa aaacttgcag taaatgtcac
    55621 tgttgtctct tgaggataat agccaagatc atagtattga ccagaaatgt tgatttgcgt
    55681 ttttcgcgat gtaccattga cagtgatcgt cgcactagaa ctttctaatt gcgcaaaatt
    55741 ggttgggaac aaacttaagt aagcttgtgt atttgcaggc acatggactt cccaagtgag
    55801 ctcttttggc tggttatctg ctgtttctga gtaagtgacg ccagtcgttg tctttgtgat
    55861 cgtcgtattc aactgattct tcaaagtagg tgtatagaat gtaaaatact gttcatttag
    55921 accagacaat gtattgatca agtttgtctg actggtcaaa ttatctgtca ctggctgctc
    55981 aacatcatta acggacaacg gtgcagtaaa tgctagtggc aatgcattga cattctgata
    56041 cagtgtatag tcgccgcttt gaccagcttg gcggaagcca tatttactga acgtgctttc
    56101 gtttttagaa atgttatatt tgattcctgt aaacccatcc atcagcaaag tattattgtt
    56161 ataacggata ttcaaatttg tccctcttga acggaaacct aatttatcca ggtaagagga
    56221 agaattacga tttcttatag aagaaaacaa actgatacca ctgtaaccat agttgatcga
    56281 atcgtttgca gatactggat ccagattttc caagcggtaa aacgagtcgg aatctttttt
    56341 tgtttcattt acaagagctt tcaagtcagg ataaggatca gtatataaac tgcgggaagc
    56401 ataattccaa tcatcaagaa tgccatggat catactgttc gtattgacca gtgcttcagc
    56461 agacatgatc aataataaca atatactcag atgattgaat gaaagttttt tatgctgata
    56521 aaatcccaca gcaaaagcat aaatccctaa gaaaaccact gtcaatacaa aggaagtcat
    56581 cgtcacatag gtgtagcttc cttcaggttt gatgccccat gccaccgcaa agagagcagc
    56641 tacgaccaaa atgattccta acaacagccc acgatcgtct tgttctatct tttcccatcc
    56701 ttttcctgca agcaggagca ctaagaaaga gaacagatag gcataacgga ataaaaacat
    56761 attcggtgca tgcataccat gccagaacaa attcaatgga acaagataaa aacttgcgat
    56821 aagtatggcg aaaagactgc cgtacaaaaa tttatttttc aacggtactt tccgactggc
    56881 aaaataaaac agacagagga ctaatggtag cagacctgcg taaacgaacg gaatcgatcc
    56941 gtattttgtc gtgtcataaa caccaatcat atttttcatg attagatcca gataagaagt
    57001 cgcttctgtt ttcaacgtag tgatctgact cagtgcctcg ccatttgacc gaagatccag
    57061 cactgctggc aatacaatga tcattgaagc gccgcctgcc agtaaagaag tgataccata
    57121 aggaacaatc gtttttttat attctgacca gtttgtcaat agacgggcga taaaatataa
    57181 gaaagaaaat acgccaatca taaaacccat ataaaaactg gataaaaaca agagtaaata
    57241 actgataaat aaaagtttcg gccgtttaag atccataaca cgatgaatcc ccaaaatcac
    57301 taatggaaga taaacaaatg catccagcca catgatgatc tccgaatgtg cagtgataaa
    57361 tgagatcaat gcgtaactga cgctaagtgc aacatgcccc cagcgaggaa tcttgaacgt
    57421 acgtgcaaga aaccaaaaag ccaatccggc acagccgacc ttaagcaaag tcagaacata
    57481 cagtgcatct ggcatcatct ggtttggaaa aaagaacacc agtggcgtga agatcccgcc
    57541 tagatagtaa gaaattaaag ataaataatt caatcctaga gaagcattcc atgtataaaa
    57601 aatactttgc tttccaagaa gaacatttcg gaagctggca tgaaaattag aaaactgtga
    57661 aaaggcatca cttgccaaaa tacttctgct gcttccagga tagattccga tacttagata
    57721 aacaagtgct aaaatcaaaa acggaatcag gaaactagct gctgcgtagc gtccgttttc
    57781 tctaaagaat gactttaaat tttttttcat atttattttc caccaaattt ctatgaagtt
    57841 gtattcagtt tatcatatcc ttgtttttct ctgcttaaaa agagtctagt tttcacaaaa
    57901 aaataaaatt tagaataaat aacttcataa tttgttcgta taacaaaaat aaacgcaaaa
    57961 aaagggtagg aatcaaaagt cccaccctta aaaattttta ttaaataaaa aaccgttcac
    58021 tatctgaacg gtccaagtat cattcaatta aacgcgttca acttttcctg atttcaaagc
    58081 acgagttgac acccaaactt ttttaggttt tccgtcgacc ataacgcgaa ctttttgtaa
    58141 gttaggttta acagtacgtt ttgttgagtt catagcgtgt gaacggttgt ttccactttt
    58201 tgtcttgcga cctgtaaagt aacaaacttt tgccatggta atttcctcct ttgccttgat
    58261 ttggagcaat agaataattc agctcatacc agactaacat atcatataga atgggaattt
    58321 gcaagtacat tttcatagat acaattgaca attgagaaga ataattgtaa attaaacaag
    58381 gttatacctg aaattttgca aggtttttga gtactttggg taactgcctt ttatttcaag
    58441 ttgcgctatg ataaaatatg atagaagaaa aatgggagtt ttttacccgt taaggaggct
    58501 cattcatggc tgtaaaaatt caaacgtcag ctggaaccat tgaaattacc aatgatgtaa
    58561 ttgcaacagt tgttggtggc gccgcgacag atgtgttcgg tgttgtagga atggccagca
    58621 aaaatcaaat taaagataat attactgaga ttttgcgtaa agaaaattac tcaagaggag
    58681 tagttgtccg ccaagaagat aatggtattg ctgtagatgt ttatacgatt atcagctatg
    58741 gtacgaaaat ctctgaagtt tcccgcaacg tccaagaaaa agtgaaatac aatctagagg
    58801 cattattagg cgtaactgcc aattcagtta atgtctttgt acaaggtgtt cgtgtactgc
    58861 cagactaggc aggagactgg ctggtaactc agcagtcgat ctgaaggagg attatctagg
    58921 tgagtgtaac agaaataagt gcaagccagt tccaggaaat ggtccaggca ggtgcgaatc
    58981 gtctgcaagt aaatgcagaa tacgtcaatt cattaaatgt attccctgtg ccagatggcg
    59041 atacgggaac aaatatgaat ctatctatga ctagtggagc taaggcagta gtagattcaa
    59101 cctcagaaaa agtaggagaa ttagcagcaa tgctttcaaa aggattgctg atgggtgcgc
    59161 gcggaaattc cggcgttatt ttgtctcaat tgtttcgtgg attttctaag caaattccag
    59221 atgttgtctc attaaatgct tctgatcttg ctgcagcctt cactcatgga gttgaaactg
    59281 cgtataaagc agtaatgaaa ccagtagaag gaacgatttt gacagtagct agagaagcag
    59341 cgaaagctgg agaaaagaaa gcaaaaagta ctgatgatgt cgttgaagta atgacagctg
    59401 ttgtaaaagg agcaaagcgt gctttagcta aaactccaga cttgcttcca gtcctaaaag
    59461 aagtcggtgt cgtagacagt ggagggcaag gactgctgtt tgtttatgag ggctttttaa
    59521 gtgcattgaa tggagaattc caagcggatg aaacatatga accttctcca gcagaaatgg
    59581 atgatatggt caatgcagaa catcatcgca gtgtccaagg tcaaatggcg acagaagata
    59641 tccattttgg ttactgtaca gaaatcatgg taaaaatcgg agaaggacct acagtcgata
    59701 gtacattcga ttacgaagaa ttccgtaact atttagatgg tataggagat tctttacttg
    59761 tggtcaatga tgacgagatc atcaaagtcc acgtgcatac agaaaaccca ggagaagtct
    59821 tgaattatgg acaaaaattc ggttcattag tcaaaatcaa agtcgacaac atgcgcttgc
    59881 agcatgagac gattttggaa cacgatgaag aagtgaacga gtttgcgaaa aaagaaatac
    59941 cacgtatccc gtatggtatc gtagcgatcg ctgctggtaa aggcgtccaa gagctgtttg
    60001 aaagtttagg cgctaattat gttatcagtg gtggacaaac aatgaatcca agtacggaag
    60061 acattgttaa agcgattcaa gaagtaaacg cagataaagt gattgtcttg ccaaacaata
    60121 agaacatctt catggcagct gatcaagcag cagaagtagc agatatccca gtagcagttg
    60181 ttccttcaag aacgatttcc caaggattga cagctatgct ttcattcaat gatcaagctt
    60241 ctttagaaga aaacaaagaa acgatgacag aaatgttgtc tagcgttgtg agcggtcaag
    60301 tcactcacgc gatcagagat acctcaattg acggtgtaga gatcaaagaa ggagactttt
    60361 tgggcatgat cgatggaaaa atcctgatct ctaacccaga tatcacagca acagcgttaa
    60421 gtacactaga acaaatgatc aatgaggaca cagagatcgt aacgatcttg gcaggtgatg
    60481 aaggaacagt tgaacaagca aatgaatttg ctgagaaact aacagaaaaa catcctgatt
    60541 tggaaatcga gatccaccaa ggagatcagc ctgtctatcc ttatctattt tctgctgaat
    60601 aatttctgtg tcagaatatc tttctaacac agtattcatt cataaaaggc cttcggttag
    60661 tgatcaggta tgatcgctga ccaagtcctt tttttgttaa aggagggagg aaaaatttat
    60721 gcgttcttta gatgatccaa tcactatgct ggcaggagtc ggagaaaaaa gagcagctag
    60781 tcttgccagc ttgggcatcc aaacgattga agacttactg acttattatc cttttcgcta
    60841 cgaagatatt caggaaagaa atctaaacga gatccaggat caagaaaagg ttactttgaa
    60901 aggaatcgta gtctcgcctc ctgtgatgaa tcgatttggt tataaaaaaa gccgattgca
    60961 atttcgtatg atgcaagaac atgatgtgtt caacgtttct ttttttaatc aaccttatct
    61021 aaaagaaaaa gtcattttat cggaggaaat cgccgtatac ggtaaatggg atgcaaagcg
    61081 taaagccttg aacgggatga agattttagg ttctcaaaca atggatgact tttcgccgat
    61141 atatcacgtc aacaaatcaa ttcgtcaaac gacattagtt gatctaatca aaaaagggtt
    61201 tcaagaatac ggcacattga ttgaagaaaa tctgccaaac aaccttgtgg agaaatatcg
    61261 actgcttgac cgagcttctg ctgtaagaag tatgcatttt ccaaaagacc acgaagaaaa
    61321 ccatcaagcc aaacgacgtg tcgtttttga agagttcttt ttatttcaaa tgcgtcttca
    61381 aggattgaaa aaagcagaaa aagcagaaac gaatggtttg gagatccttt atgatgtcca
    61441 aaaattgaaa caatttactc aaaagctacc ttttgaactg acaaatgcac aaaaacgtgt
    61501 aacgaatgaa atctgtcggg atcttcgcag tccgcagcat atgcagcgac ttttgcaggg
    61561 agatgtaggt agcggaaaaa cagtggttgc cgcgattgcg ttatacgcta ccgttacagc
    61621 aggtttccaa ggtgcgttga tggtgcctac agaaatcttg gcacaacaac atatggaaag
    61681 cttgcaacag ctgtttgatc ccaatgaagt aaccatcgca ttgattacgg ggtcaacgaa
    61741 agcaaaagaa cgacgtgagc tccttgaaaa actagagcaa ggggaaatta acgtcgtgat
    61801 cggcacacat gcattgatcc aagatggagt cgaatttcag aatttaggtc tagttattac
    61861 ggatgagcag caccgttttg gcgtgaacca gcggaaagta cttcgtgaaa aaggctggcg
    61921 accagatgtc ttatttatga cagcgactcc gattcctaga acattagcta ttacagcata
    61981 tggtgagatg gatgtatcta tcattgatga acttccagct ggacgtatcc cgatcgaaac
    62041 acgctgggta agaacacctc aattggacag tgtactggat tggacgaaaa aagaactggc
    62101 aagaggacat caaatgtatg tcatctgtcc gctgattgaa gaatcagaag cattagatgt
    62161 aaaaaatgca gtggaaatct atgaaaaact tcgtgaacta tttgcaccaa aatatgaagt
    62221 tggcttgtta catggtaaaa tgaagaatca ggaaaaagaa gtaatcatgg aagccttcaa
    62281 agacaaccag atgcagatat tagtttcgac tactgtaatt gaagtagggg taaacgtgcc
    62341 gaacgcgacc gtcatgctga tcatggatgc ggatcgattt ggattggcac agctgcacca
    62401 acttcgtgga cgtgttggac gcggaagtga tgcttcctac tgtatcttag ttgctaatcc
    62461 taaaaatgaa ctaggtgtgg aacggatgaa aatcatgaca gagaccacca atggttttgt
    62521 actaagcgaa aaagatctgg aattacgtgg tcctggtgaa gtatttggct tccgtcaatc
    62581 tggtctgcct caatttgcga ttgctgactt ggtgacggat ggaaatgttt tggaggtagc
    62641 cagagaagag gctgcagccc tttggcaaat aaaggattgg cagatgcttc ctgagtatca
    62701 gcctttagcg caaagcctcc aaatagaaaa tcaggataat cgttatttcg attagcagac
    62761 tgtgctatac tttatactga tgacggaaaa aggagtggaa acaatgaaaa ttgccgtaga
    62821 tgcaatgggc ggagatcacg cacctcaagc aattgtagaa ggcgtggctt tagcgcagca
    62881 agattttcca gaagtagaat tcttacttta cggaaaagaa gcagaaatca agaaatactt
    62941 aacaaatgaa aaaaacatca cgattatcca tacagacgaa aaaatcaata gtgatgatga
    63001 gccagtaaaa gcaattcgac gaaaaaagac tgcatcaatg gtccttgctg cacaagcagt
    63061 gaaaaacggt gaagcagatg ctgtattttc agcagggaat acaggcgcgc tactagcagc
    63121 agggttgttc atcgtaggac gtatcaaaaa tatcgaacgc cctggcttga tgtctacctt
    63181 gccagtagta gggaaagaag gtgccggttt cgatatgctg gatcttggcg ctaacgcaga
    63241 aaacaaacca gaacatttgt tgcaatacgg tattttaggt tctttttatg cacgtaaagt
    63301 ccgaggtatc ggacgtcctc gtgtcgcact cttaaacaac ggaacagaag caacaaaagg
    63361 tagtgaagtg acgaaaaaag cctatgaact ccttcagaat gaaacaagct tgaattttat
    63421 tggaaacgta gaagctcgtg agctactcaa tggtgtggct gatgtagtgg tcacagatgg
    63481 atttacaggc aacgctgttt tgaaatctat tgaaggaaca gcaatgaata tgatgaatct
    63541 attaaaatct gctattctaa atgaagggat caaaggaaaa atgggcgcta tgcttttaaa
    63601 agacggctta cgttctttga aagcagaaat ggattattcc aaacatggcg gtgccgtttt
    63661 gtttggcttg aaagcaccag tcattaaaac tcatggagca acaggccccg atgctgttcg
    63721 ctatacgatc cgccaaatcc acacaatgct tgagacagat gtagttggac aattagtcga
    63781 acaatttgaa aaaagcgaag aatagtattt ggatatctga agcgatccgt tccattgaaa
    63841 aaaaggtgga cattcctgaa aaatgccagt aaaattagcc atggtgtagg taattgacaa
    63901 gtgtatgatt cttggaggtg aaaaagttga ctcgcgaaga agtatttaac aaagtagcga
    63961 aaattatttc aaatcatttt gagatagata ccgataaagt gacggatgaa ttgaacatca
    64021 aagatgattt aaaagctgat tcaattagta ttatggaatt cgttttagag cttgaagatg
    64081 aattcggtac ggaaatttca gatgaagacg ctgaacaaat tgaaacagtc ggtggcgcag
    64141 tagattatat cagcagccat cttaaataat ttcaaataaa agcaaagaag gataaaaagc
    64201 tgcatgcagc tttttatcct tcttttttta atctttttga cacgtaaaag tcatttttct
    64261 gataattctg gcgataaaca gaaattatgt tgcaaagtaa agcggttttc tatataatta
    64321 ttaataattc attacacaaa gataagaata acctttgtta taaaacgatt tattctgtgt
    64381 aatgtccttt tttattaaga aaaacttcca tttaggaagc agagaggggt attcgattgt
    64441 ccgataacca attattagaa gttcagaacc tacatacagg attccgactc aaagatgact
    64501 attacgatgc agtagatgac gtttcattta ctttagacaa aaacgagatt ttagcaatcg
    64561 ttggggaatc tgggtgcggg aaaagtacct tggctactac gattatggga ttacttgatc
    64621 ctaataacac aaaaattaca ggtgagattt tatataacga tctgaattta atcgacctga
    64681 acgaaacgct ctataataaa atccgcggaa atgatatcgg aatgattttc caagatccgt
    64741 tgtctgcatt aaatcctctc atgagaatcg aagaccagat caaagaagga ctttcctatc
    64801 acacaaagat gaatgcagaa cagcgtcaag ctcgtgcact agaattgcta gaacaagtag
    64861 ggattcctaa tcctgcgaga gttggacgcc aatatcccca tgaactatca ggcggtatga
    64921 gacaacgtgt catcatcgca atcgcaatcg cctgcaaacc tccaatcgtc attgcagatg
    64981 aaccgacgac agccctagat gtaaccatcc aagcacagat tcttgattta ctgaaagacc
    65041 ttcaggaaga aacaaaaaca gggatcatct tgatcactca tgacttagga gtcgtagcag
    65101 aaatggctga tcgagtggca gtgatgtatg gcggacagtt cgttgaagta gcaggtgtaa
    65161 aagaactgtt tgatcatcct aagcatcctt atacacgctc tttactgaac tctataccac
    65221 aagaaggaaa tcatgatgca gaactccatg tgatcgaagg tgtcgttcct tctctgaaaa
    65281 acatgcctcg taaaggttgt cggtttgcac cacgtattcc atggatacca gcaagcgatc
    65341 atgaagaaga gcctatcctt catgaagtcg caccgaacca cttggtacgt tgctcctgct
    65401 ataagcattt ccactttaga gacgaaaaag gagaggtgta gatgacagaa ttaatcacaa
    65461 tcaaagacct gaaagttcat taccctattc gcagtggatt cttcaatcga gtaacggatc
    65521 atgtatatgc tgtagatggt gtggatttta ttatcgaaaa aggaaagaca tatggtttag
    65581 tgggagagtc tggctctgga aaatctacta cgggaaaagc cgttgtggga ttagaaaagg
    65641 taacagccgg acaaatcatg tatgaaggaa aagatgtaac gaagcgaagc aaccgcaaaa
    65701 aaatgggtta taacaaggat gtgcagatga tcttccaaga ttcaatgtcc agtttgaatc
    65761 ctaaaaagcg agtgttggat atcattgctg aacccatccg aaattttgaa cggttaagcg
    65821 atcaagaaga aaagaaaaag gtaaaaggac tgctagatat cgttgggatg ccggaagatg
    65881 cgctatataa atatcctcat gaattttcag gcggacaacg tcaacgtcta ggagtagccc
    65941 gtgctgttgc taccaatcca aaactgatcg tagccgatga acctgtatct gctctggatc
    66001 tatctgttca agcgcaagta ttgaatttca tgaaacgaat ccagcaagaa tacggcctca
    66061 gctatttatt catttcacat gatttaggtg tagtaaaaca catgtgcgac aatatcgcaa
    66121 ttatgtacaa aggtcgattt gtagaaatcg gtacaagaga agacatttat aatgacccgc
    66181 gacatatcta tacgaaacgt ctgctttcag ctattccgca aatcgatgta gaaaataggg
    66241 aaagccacaa agaaaatcga cgaagagtag aacaagagta tatccaaaac caaaaagaat
    66301 actatgatgc gactggtcga gtctacgatt tgcgtacgat cacaactaca cacaaagtgg
    66361 cgttgaaaga tggaggtgca agctaatgtg gaaaacgatt ctgcgacgtg ttttattgat
    66421 gatcccgcaa gttattattt taagtgttct gatcttctta ttagcccaag cgatgccggg
    66481 ggatccattt accggtttga tcaatccaaa tcaggatccg gcagtgatcg aacagatgcg
    66541 acaagcagct ggcttgaatg acccatggta tgtccagtac ttccgttgga tcggaaatgc
    66601 tttgcaaggc gattttggtc aaagtttctt atacaaacgc tctgttgctg acttgatcgg
    66661 cgaacggatc atcaacactt tatatctatc gatcttgaca gttgtcctta cttatttgat
    66721 tgctgtgcct ctggggatgc ttgctggccg gtatcaaaat tcaatcttgg ataagattgt
    66781 cgtaatctac aacttcttta gttttgctgt tcctttattt atcttcggct tgatcatgct
    66841 atttgttttt ggttatcgtt taggctggtt cccaacaagt ggatcacaaa cactaggttt
    66901 gcaaggtgga tttatcactc aatggataga ccgtttgaaa tatattctgt taccatcaat
    66961 tacccaagca tttttggcga ctgccgtcac aatccaatat ctgcgaagtg aagtaatcga
    67021 ttcgaaatcg ctcgattttg tcagaacagc ccgttccaaa ggggtaccga cgaataaagt
    67081 attcagtcga catattttcc gaaatgcagc gttgccgatg gcttctcaaa tggggtatga
    67141 aatcacttcg ttgattgctg gttctgtagt tatcgaaaag atttttggtt atccgggagt
    67201 cggaaaacta tttattgatt ccatcggcca acgggactat accgtgatca catccttagt
    67261 attgatttta ggaatcgcga cgctagtggg gacattactt tcagatatca tcatgagtat
    67321 cgttgacccg cgtattcgga ttcaataaaa ccaatcagaa aggagaatgg atcgatgagt
    67381 gaaaaaaaca atacagcagt tcaagaaagt attcctccta tggggatacg aatgattgct
    67441 cgagaattta aaaaagataa aattgctatt ttttcattag gtttgctagt ggttttatta
    67501 ttagtgatct ttatcggtgc gatgctgacc gatcaagaca aagtgatgta tgttagtatc
    67561 ttcgacaaat acgctgcacc aggaacagtt tcgacacaag gacaaaagtt cattctggga
    67621 gcagatgaag gcggacgtga tgtattagga caattgatca taggtgctag aaactctgtt
    67681 acgatcggat ttgcgatcac gatccttact tcgatcatcg gggttggatt agggatcatc
    67741 tctggctact acggagggat cattgacaac atcttgatgc ggatcgttga ttttatcatg
    67801 attctaccga tcatgctgat cattatcgtc ttcgtatcga ttatttccag atacaatgtc
    67861 tggtccttta tattcatcat gagtgcattt tattgggtag ctaaagcccg attattccga
    67921 agcaagacat tatctgaagc aagaagagat tatgtcagtg cctcaaaaac aatgggaacc
    67981 aatgatttta aaatcatgtt ccgcgaaatc atgccgaatc taagttcatt aatcattact
    68041 aatttgacga tgaactttgc ggcaaacatc ggtatcgaga caactttgac tttcttaggt
    68101 ttcggcttgc cggcaaatgt acctagttta ggtacattga tcggttatgc aagtaacgga
    68161 gaagtcttag tgaatcggca atggatctgg ttacccgcat caatccttat tttagttttg
    68221 atgttgagta tcaattatgt tggacaagca ttcaagcgtt ctgcagatgc gcgccaacgg
    68281 ttaggctagt atagaagcga agggggaaat aggaatgaag aaaacgattt ttggatttgc
    68341 agcgctgatg tctgctgtcg ttcttgcagc atgcgggggc ggaggtacag atacctctgg
    68401 aaacaactct ggaggcaacg gcaataacaa agaggaatta acttttccaa ttgcaacaaa
    68461 aaataatgat gatgcaatcg aagacggcga attagaagct gcggtcgcaa cggacagtca
    68521 gtttaaagga ttgttccagt gggagtttta ccaagattca tatgatgcag cttttatggc
    68581 tccttctcat gaaccgctat ttgcaaacga tgacgatttc agaatcacag acgacggagc
    68641 tgcaacgctt gatctagatg aagatacgaa aaaagcgaca atcaaagtaa aagacaacgt
    68701 caaatggtca gatggtgaag atgtaacggc ggacgatgtg attttccctt acgaaatcat
    68761 tgggaataaa gattacactg gtatccgtta tgacgacact ttccgtaaca tcgtaggtat
    68821 ggaagaatat catgatggaa gtgccgacac aatctccgga atcaaaaaaa tagacgacaa
    68881 aacagttgaa atcgaatata aagaagtaaa cccaagcatg cttcaatcgg gtggtggtat
    68941 ctggtcatat gcagcaccaa aacatacgtt agaaggtgta gcaatcaaag atatggaatc
    69001 aagcgatcaa gtacgtaaaa atccagtgac ttttggccct tattacatga gtaatatcgt
    69061 tgcaggagaa tcagtagaat acttgccaaa cgagcactac tggaatggta cgcctaaatt
    69121 gaaaaagatc acgatgaaat ctgtaccgat ggcaagtgca actgaagcat tgaactctaa
    69181 attatatgat atgattttcc aaatgccaac agatacttac gatacctata aagaaattgc
    69241 tggctataca aacttaggcc gtgaacaaac ttcttatact tatctaggat tcaagttagg
    69301 taaatggaat gcagatacaa agagtgtgga atacaatcca gattcaaaaa tggctgataa
    69361 atcattacgt caagcaatgg gctatgcatt agataataat gcagtaggtg aacgtttcta
    69421 tgcaggtttg agaagcaatg cgacttcatt gattcctcca gtattccagt cataccatga
    69481 tgatgagatg aaaggattca cacaagatct agacaaagcg aaaaaactat tagatgatgc
    69541 tggctacaaa gatgtggatg acgatggttt aagagaagac aaagatggaa ataaactaac
    69601 aatcaacttt gcttcgatgt ccggtgggga aacagcgcaa ccattggcag attactatat
    69661 ccaacaatgg aaagaaattg gtttggatgt ccaatacaca acaggtcgtc tgatcgaatt
    69721 caattctttc tatgataaat tagaaaacga tgatcctgaa attgatgttt accaagctgc
    69781 ttggaataca ggaactgatc caaatccaag tggactatgg ggaccaaatg ctgcgttcaa
    69841 ctacactcgt tatgaatcag aagaaaatac aaaattgatc aacgatatca gttcaagcaa
    69901 agcatttgat gaagagtacc aaaaagaagc atatcaaaaa tggcaacaat atgcatttga
    69961 agaagcattt gcgattccaa cgttgttccg taatgaagta ttgccagtca acgaccgtgt
    70021 caaagactgg gattggtctt atgatgtacc aaacccatgg gcaaatgttt ctgttacagc
    70081 agattcacgt tcataatcac taaaaatgac cgaaaaaggg cgatgtcctt tttcggtttt
    70141 ttgatatttt tctgtttatt tctctaatat tcaggtcaag gcgctgattt catgacttct
    70201 ccaataaacg gtgttcaaag tccagtttct cggtattaag tcaaatttat gcaaaaatat
    70261 ggaaagccat tttcacaaaa ttttttcttc atactcgaaa ctaaacgaat ttttcacaac
    70321 ttctcgtcaa tcactaggat tattaaagct ttacttacct tttgaccgaa ccatttcaaa
    70381 tttgacaaaa aaccagtata ataaggaagt atcgaaaaaa tatccataaa aggaatgtgg
    70441 aaaatggaca accagctgac aaaagaacta aaagaaaact ataacatcgt ttttcacgat
    70501 ctaaatttgc ttgaacaagc ttttacccat tcatcctatg tgaatgagca tcgcaatctg
    70561 caattatcgg ataatgagcg acttgaattt ttaggagatg ccgttttaga actgatggtt
    70621 tctcagtatt tattccgttt atatcctcat ttgccagaag gaaaattgac aaaaacacga
    70681 gctgcgatcg ttcgcgaaga cagcttgtcg aaatttgcca aagaatgtca ctttgatcaa
    70741 tatgttttgt tgggcaaggg agaagagaat tcaggaggac gtacgcgacc agcattgctt
    70801 tgcgacctat tcgaagcttt tttaggcgcg ttatatcttg accagggatt cgacacgacc
    70861 catgcattca tcgaaaaagt gatttttcct aaagtcaaag caggtgcttt ttcacatgag
    70921 atggatcata aaacaaaact acaagaagtc ttgcaaaaat caggtgatgt atcaatcgaa
    70981 taccgattga tcaatgaaga aggtccagct catgaacgag tattttggat cgaagtttat
    71041 gtagatgatc aattgattgg cactggacaa gggaaatcga aaaaattagc agaacaagct
    71101 gcggcggaaa atgcattggc agcactgtaa aagtaagtga gggaaagctt tgtatttgaa
    71161 acgaattgaa atagccggtt ttaaatcatt tgcagacaag acagtcattg attttgaaaa
    71221 tagcgtcaca gcagtggttg gaccaaatgg cagcggaaaa agcaatatta cagaggctat
    71281 ccgctgggta ttaggagaac aatctgctaa aagtctgcga ggcggaaaaa tgccggatat
    71341 catctttgcc ggttccgata cccgtaagca gctgaatatt gcagaagtca cagtgatttt
    71401 agacaatagt gatcattatc tgccattgga gtacaatgag atcagtgtaa cccgccgtta
    71461 tcgacggact ggggaaagcg agtttttcat caataaacaa agctgcagat taaaagatat
    71521 ccaagaattg ttcttagatt ctggattagg aaaagaatcg ttctcaatca tttctcaagg
    71581 aaaagtagaa gcgattttca gtagtaaacc ggaagaccgt cgtgggatct ttgaagaagc
    71641 agctggtgtc ttgaaataca agcagcggaa aaagaaagca gaacagaagc tttttgaaac
    71701 agaagacaac ctcagccgcg tccaagacat catccacgaa ttggaagaac agttaactcc
    71761 tttggccgcc cagagtgagg cagcaaagga gtttttacgg ctaaaagaaa cactgactca
    71821 aaccgatgtc tctttgatgg ttgctgaaat caagacagca aaaaaagatt gggacaacaa
    71881 acaagcacag cttgcgaaat tcaatctaga attaggcaaa ctatctgagt cgatccaaga
    71941 acaagaatcc attttggcga agcagcgtaa agaaaatgcg caagccgatc gtctgatcga
    72001 aaaaaatcag caagtattat tagatctttc ggaaaaactg aagcagacag aaggacaaaa
    72061 agatgttttg caggagcgga caaagcatac acaaaaaagc tcgcaagaat atcaaacttc
    72121 attagcagaa gcacaaaaaa aggttaaaca ttttgaaaag cttcaagaaa gcttgatgaa
    72181 agcagcagca gaaaaagaaa cagagatcca aaaagctgaa gcaaatctca taaaaacaca
    72241 gcaagaatta gaaaaatacc aaaaatcaac gaaagaatta ttggcagaat taagagatca
    72301 atatgttgat ttgatgcaag aacaagcagc tgtaggaaac gaactgaagt atctagaacg
    72361 tcaatatata caagaaacag caaaaagcaa gcagacgtta gccaagcaat cggaagtaga
    72421 agcatcagta gaccgattga tcttacaaaa agaagaattg acacaaaagc aggcgcagct
    72481 aaaatcatct ttaactgaaa caaaagagaa gttagaaatg atccaacaaa acgggaaaaa
    72541 gttccaagaa gcattagcaa aagaacagcc taaaatgtat caattaatga atcaagtcca
    72601 gcagctacgt gctcgtaaga aaagccttca agaaatccaa gaaaactatt ttggttttta
    72661 ccaaggggtt cgattggtct tgcagcataa acagcagctt tcgggtattg tcggagcagt
    72721 ggctgaactg atcgatgttc ctgcagattt cacgttagct atcgaaacag ctttaggtgg
    72781 ggcagcccag catgtcatcg ttgaaaatga aaaagatgct cggcaagcca tcacgtattt
    72841 gaaacagcaa agaggaggaa gagcaacatt ccttccactg acgacaatca aaccaagaca
    72901 attaccggct catatattga cacaagcagc agctgtagaa gggtttatag ggattgccag
    72961 tgaacaagtc agttatcccg atcaaatcca aactgtggtt caaaacctgc taggaacgat
    73021 ccttttagcc aaagacttaa ctagtgccaa tgcaatcgcg caaacgatcc gctatcaata
    73081 tcgagtggtt tccttagaag gtgatgtgat gaatgccgga ggatccatga caggtggagc
    73141 gaataaacga ggaaaccaag gcagtttgtt tgtacaaaat caagaattga aacagttgac
    73201 tagtgaattt gaagaagcag ataaacaact ccaagcacaa gaaaaaaaag ttcaggagct
    73261 gcaacaagaa acagctcgtt tagccgaaga acaagaagtt ttgcgtacac gaggcgaaca
    73321 attacgtttt gaagaacaag aagcgacaaa tcagctacaa aacatcataa atgaacttga
    73381 acgttttgaa aaagaaaagc aaatctcaac ttttgagaca cgtgaactgc agcagtttat
    73441 cgaagattac gaaaagcaaa cgaacgaatt gaaagacaaa caaacagatc ttgaatcgca
    73501 acgacaaaaa atcgacgaag aaatcaaatc gttaagtcaa gaaagcgacc agatggaagc
    73561 cagaagagca caagtacaaa gtcaaaaagc acaagaacaa gcagatcttg ctgtcttgaa
    73621 agagcagttt aatcatctgc agatccagct ccgcggtgcc cgagtccaaa aagcagaggc
    73681 aaccgaacgt caagaagcga tagaaaagca gttggcgaca ttgacagcag acttttctga
    73741 tcatgaagtc acagaagaaa gtttggaaaa acaaattaac gaattatctg ctcagcgaga
    73801 aacattaaaa gccgagttgg caaaagccaa agagcagcga gatagaaggc aaaaggagat
    73861 cgataagctt gaagcagtct tggcagagcg taatcgtgag caaaaagcac gactgtcgga
    73921 acaatccaaa ttagaagtcc aaaaagaccg agctgaaatg attttagata atcatttgac
    73981 ctatctgcag tcagaatatc agctgacatt tgagaaagct tcccaagact atcaagaaac
    74041 aaccgatatc gaagacagta gaacaaaggt ttcatcctta aaagaacaga ttgaaaaact
    74101 gggaccagta aacttaaatt caatcgaaca atacgaacaa gtcagtgaaa gacatacatt
    74161 cttagcaaca cagcgagatg atctgttagc agcgaaaaac caattgtttg aaacgatgga
    74221 tgagatggat gatgaagtgc ggacaagatt caaagaagta tttgaagcta tccgtcaaga
    74281 attcaaaatt gtctttccaa atatgtttgg cggcggtaaa gctgaattag tactgacgga
    74341 accaactgat ttgctgaaaa caggtattga gattgaagta caacctcctg gcaaaaaact
    74401 gcaaagtcta agtttgcttt ctggaggaga acgagcactt acagccatcg cgttgctctt
    74461 ttccattatc cgtgtctgtc ctgttccgtt ttgtatctta gatgaggtag aagcagcgtt
    74521 agatgaagcc aacgtgaaac gttttggtcg ttacttgagc gatttccaag atgacacaca
    74581 atttatcgta gtcacacacc gcaaaggaac gatggtcgca gcagatgtac tgtacggagt
    74641 gacgatgcag gaatccggtg tatcaaaaat cgtttctgta cggatggaag atatcaatga
    74701 agaggcgaaa atcaacgaaa cgaaagtgta ggaacgaaaa tgatcaaatt agtagcaatc
    74761 gatttggacg gtacattatt aaatgaacaa aagctgattt cagatgagaa taaacaagca
    74821 ttagcacaag caaaacagca aggggtcaag atcgttctat gtacaggacg ccccttagct
    74881 gcgatggcgc attatctgca agaattagga ctggtagatg aaggtgacta cagcatcact
    74941 ttcaacggcg gtttggtaca aaaaaatgat actggtgaaa tcatggaaaa gaaagtgatg
    75001 gaagtatcag atatccaacg cttatacaaa ctggctcagc aattggatct gccactagat
    75061 gttttgtctg acaatgtggt tttacagctg cctagtgccc caaggaagca atccttgtac
    75121 aatgtgttga ataagctgct gcaattccaa ccagcggata taagcgatat tacagatgaa
    75181 tttgtgctta ataaggcagt aatcgcttat gaccaagaag aattagatcc taaaatcaaa
    75241 gaaataccag cagaattcca tgaaatgtat gagatcatca aaacaagaag tatgcttttg
    75301 gaatttatgc caaaaggtgt tacaaaagct tatggtattt ctttattggc aaaagatctt
    75361 ggtttgaaac aagaagaaat catggcgatc ggtgatgagg aaaatgattt accgatgatc
    75421 caatatgctg gactaggcgt agcgatggag aatgctgtgc ctttcgtcaa agaagcagca
    75481 gatttcgtga cagccagcaa tgaagaaaat ggcgtagcca aagtgatcca aaaatttgta
    75541 ttagagtagg gggagtcaaa tgggattttt tgataaaatc aagcgtgctt ttactggcga
    75601 agagaaaaca gaagaagttg aagtacagga gaagtacgac aagggtttag aaaagacgcg
    75661 taaaacattt ggtgaacgga tgaatgagtt gtttgccaat tttcgaacag tcgatgaaga
    75721 cttttttgaa gaattagaag aaacacttat cggtgcagat gtaggttttg aaacagcgat
    75781 acgaatcacc gaagcattac gtcaagaagt gaaactcaga aatgcgaaaa aatcggcaga
    75841 agtccaaaat gcgatcatcg agaaacttgt ggatctctat gaagcggaag gaatcaatga
    75901 agtaaatgaa ctaaatatcc aagaagacgg actaacagtt attttgtttg tcggtgttaa
    75961 tggtgtaggg aaaacaacaa gtattggtaa acttgcccat cagttcaaaa acgaaggtaa
    76021 aaaagtattg atggcagcag cagatacctt ccgcgctgga gcaatcgacc agttagttgt
    76081 ctggggcgaa cgcgctggtg ttgaagttgt tcgtggcaat gcaggaggcg atccagcagc
    76141 tgtcgtattc gatgctttgg aaagagcaaa gacagagcag gcagatgttt tactagttga
    76201 tactgcaggc cgactgcaaa ataaagtgaa cttgatgaac gaattagaaa aaataaaacg
    76261 agtaatccag cgggaattac cagaagcacc ccaagaaaca cttcttgtat tagatgcaac
    76321 cactggtcaa aacgcgatgg ttcaagcaaa acaattcaaa gaaacaacag atgtgaccgg
    76381 tcttgttttg acaaaattag atggtacagc aaagggcggt atcgtacttg ctatccgtaa
    76441 tgaattgcat ttaccagtga aattggtcgg tcttggtgaa ggaatcgatg acttggagcc
    76501 gtttgatcca aatgattttg tcgttggatt gttcaaagga ttactaaaag aagaataacc
    76561 catgtctaaa aagcaggagc tgtgacaaaa gttgcagctc cttgtttgaa tgattgtttt
    76621 taacatagct gtgtttttga tgccttcatt tttatactta tttgtaagcg gttctcaaac
    76681 aatttcgttc tttttcttag actttttgat tataattaga ttcatatgaa ttggaggtca
    76741 cttaatgatg aattttaagc aattattatt gcatgtcaat gcgcgccctt ttatcgacca
    76801 agctcgattt ggtatagaac gggaaggaca gcgggttgat cttgcaggaa atctagcaaa
    76861 aaccgatcat ccagcaatct ttggcgatcg atcctatcac ccctatatcc aaacagattt
    76921 tagcgaaaca caaacagaga tgatcacccc tgttaccgat tctattcccg aattatttca
    76981 gtatctcgct gctgtttatg atgtgactgc tcgttctata ccgaaagaag agatgatctg
    77041 gccattaagt atgccacctg ccttaccgga aaaagacgaa gagatcatta ttgcaaaatt
    77101 aaaaaatttc gaagatgtct tgtatcgacg ttatttagca aaagaatacg ggaagcgaaa
    77161 acagatggta agcggtattc atttcaattt tgaatttggc gatgagttgc taagaacatt
    77221 gttcagccat caggaagaat ttcaagattt ttccgaattc aaaacagaac tttatttgaa
    77281 aacagcgaga aactttatgc gctatcgctg gatgatcact tatttattcg gtgcttcacc
    77341 aatgagtgag aagaactact ttttagatga atcacatccg caagaacctg ttcgcagtat
    77401 tcgcaacagt gcgctgggct atacgaatca tccaaatgtg aaagtttcct atgcttctat
    77461 gaaacagtat ttagcagata tcgagcgaat gatcgaagaa gggaaacttt cggaggagaa
    77521 agaattttat acaccgcttc gtttccgagg cggaaagaaa gtcgcagatt tagcaacaac
    77581 aggtgttcgt tatattgaat tgcggaatat cgatttgaat ccttatgcaa gattgggtat
    77641 caatccagag caagttcggt tcttacaatt attcctgatg tacatgttat ggacagaaga
    77701 aaaagaagac tgtgaccaat gggtagcaga aggtacgact cgaaataaca aagtagcact
    77761 agaacaacca tcagatcaaa cagaatttca tcaagaaggt agagaaattc ttgaaggaat
    77821 gaagcaaatg ctggttgaat tggattggtt ggattctctt tatttagtag aggaagcatt
    77881 gactcaaatg gatcatcctg aacaaacgtt agcagcgaaa ctctatcaag aagcacagct
    77941 atcgagtcag caagaagttg ctgtggcatt gggacatcaa tattataaag aaagccatga
    78001 acgtccctat cagttggccg gttttcgcga aatggaactt tctactcaga tatttatgtt
    78061 cgatgccatc caaaaaggtg tccaagtcaa agtattagat gagtcggatc aatttttgcg
    78121 tctgcaattc caagaccatg tagaatatgt gaaaaatgca aacatgacaa gtaaggacag
    78181 ctatatcgtc ccacttatca tggaaaacaa aacagtaacg aaaaaagtct taaaagaagc
    78241 tgggttccgg gtaccaggag gcgcagaatt ttcatccatg gaagaagcgg taaaagctta
    78301 tccgagattt gccgagcagg catttgtgat caaacctaaa tcaaccaatt acgggttagg
    78361 tatcacgatt ttcaaggaag gagctagtct ggaagattat caagcaggtt tagccattgc
    78421 ttttcgtgaa gacagttcgg ttttagtaga agaatttatg ccgggaacgg aatatcgttt
    78481 ctttgtgatc gacggagaag tccaagccat catgttgcga gtccctgcta atgttattgg
    78541 tgacagtatc cgaacagtga aagaacttgt tgaagaaaaa aatagtgacc ctttgcgtgg
    78601 aacgaatcat cgtgcacctt tagaattgat ccaattaggt gaattagaac aattgatgtt
    78661 gaaagaacaa gggttgacga tcgaatcagt tccccaagcc aatcaaattg tttatctaag
    78721 ggagaactca aatatcagta caggtggtga ttcgatcgat atgactgatg aattttctga
    78781 agcttacaaa aaaatcgccg tttctgcggt agaagcacta ggagctaaga ttagtggtat
    78841 cgatttgatt ataccagata aagaaatcga tcctacaact gataaaaaag catatgggat
    78901 catcgaagca aatttcaatc cagccatgca tatgcatgtt tatccttttg caggaaaagg
    78961 cagaagattg acgatgaatg tattgaaatt gttatatcct gaagtatttt aaaagaaaaa
    79021 gcttttgaca gattgtccta tttgatgtca atctgatcaa aagctttttt tgcatgtaaa
    79081 aatttatgtg ttttttcgtt ttaaaataaa cgatcccaga agcttttttt cttttttggt
    79141 ttttcttttt cagctggcga agagttttct tctgggtatt ttttttcgat atcaatcaca
    79201 ggttcattta ctgcttcttt tgctgttaag agcaatccga attcctcagg atttgcagtg
    79261 acgtaatcgt tgactacagt gaaacggcta ttgtttttcg ttgctagctg gatatattgg
    79321 ttttggacag aaaggggtag agccccattc aagagtatgg aagcatctgg atgttttttg
    79381 agttctttta aaaagttttc tttgtttttt ggttggatca tttcagcaac agtcatacta
    79441 agatagcagc gttccctgaa tgtccctaaa tatttatgct gttcttcagg gttcactaaa
    79501 ggtgtaccat aaagtccctt atccaaatgg ctttttacat catcttgtgc cataaaaaat
    79561 accctccttc ttctctttgt ctttcttacg attatagcat attcccaata atacctaaaa
    79621 catatgaaaa agcggttgct tttgttcaac gattcactta aaataagaat gaaaatcatt
    79681 ctcaattaga aaggtggatt ggatgcgcta cggacgacta gtagcattat tagttatttt
    79741 aagtagtatt tcattgttca tcggagtatc gaatgtacaa ttgtcagaac tgctccagtt
    79801 agatgggcaa agcttacaaa tcttgctagt gactcgtttg ccacgaacga tttgtttgat
    79861 ccttgtggga gcgaccagta gtatttgtgg gttgatcatg caacatttga cccaaaataa
    79921 atttgtttca ccaacgactg cgggcacgat ggatagtgcg cgtttaggta ttttagtggc
    79981 tatgattttc ctacctggtg catccttgat tgtccgatcc ttgacagcat tttgctttgc
    80041 ttttgcagga acattgcttt ttttatccct tacgcgattg ttcctccaga aaaatcaatt
    80101 gatgcttccg ttgattggag tcatgttagg gaatatcatt ggttcagttg ctactttttt
    80161 tgcttatcaa ttccagttgg tacaaaatat gacttcatgg cttcaaggga attttgcgac
    80221 tgtgatacga ggaaattatg agttattgta tgctgttgtt ccattgttgc tcttggtttg
    80281 gctatttgct taccgattta cgatcattgg tctgggcgaa tcgtttgcag taaatctggg
    80341 aatagattac cagaagatgc agtttttagg cattggctta gtatcattgg ctagtgcagt
    80401 catgttgatc atggtaggaa gcattccttt tatcggagtg atcattccga atcttgtctc
    80461 tagaatatat ggagatcaag tgcacaaaac aattggcgta actgctttag caggtagttt
    80521 gttcttagta ttttgcgatc ttgtcgctcg cgtgttgatt tttccttatg aaataccagt
    80581 cagtgtgatc gttggaatca tcggtggggc tatcttcctt tatcttctga taaggggacg
    80641 acgatatgct taaaaaaaag ccatctattt ttattggtat gcttgttctt gttttatttg
    80701 ttacaggaat gtacttgacg atccatacat atggaaactg gcattttgca tgtgcattga
    80761 ggagtaagaa aatttttgca tttatccttg tctcgctagc tgtcagcagt gccacaatca
    80821 gctttcagac aattacgcat aaccagtttt tgactccttc agtattggga cttgagtcgt
    80881 tatatgtcct tgtccaaacg gtccttttct tctttatcgg aggagtgacg atgcttcagc
    80941 agacaggtac agtttttttc ttattgaacg ttgggctgat ggtcgggctg agtctattgt
    81001 tatttttctt tcttttgaaa aaaatgagag cgaatctttt tttattactg atgtcaggga
    81061 tgattttagg tacgcttttt ggtagtgtca gtaccttttt acaagtcatc atggatccga
    81121 atgaatatga tttgcttcaa ggcagattat ttgcaagctt tggcaatatc cagagtcagt
    81181 atcttttgcc tgcttctttg atcattatcg gctgctggta cctgttattt cgatatcgac
    81241 atgtgctaga cgttttccat ctcggaaatg aacaagcagt aaacctcggg atagacacag
    81301 atcgttttga atttttgatt ttatgttgtg tcagtctttt gacagggaca tcaacggctc
    81361 ttgtgggtcc agttactttt ttagggttta ttgtcgcaaa tatcagttat cgtgtctttt
    81421 ctacttatcg tcatggtcag ctatttatcg gaagctttct ggtagctatg ctgtttctga
    81481 caggaggaca gctcgcagta gagcagattt tcggctggaa tacaacagtg agtgtcgtcg
    81541 ttgaatttgt cggaggaatt tattttgtca caaaattgat tcgcgaaagg aagagtatcc
    81601 tatgattgat ttacaaaagg tcaataaact gtaccatgga aaatcagtgg ttaaagatgt
    81661 acagttaacg attcctgaaa agaagttgac tgcttttatc ggtccaaatg gtgctggaaa
    81721 gtcaacggtg ttgtcgatga tcagtcgttt gataccaaaa gatacaggtg aaatctattt
    81781 agaccataac gaagtaaagg cttggaaatc caatgaatta gccaaaaaat tatcgatcct
    81841 acgacaatcg aatgaaataa atgtccaaat caccgtgaaa gaattagtag aatttggacg
    81901 atttccttat acgaaaggaa aattgacgac aaaagacgag gaaatcgttc aggaatcact
    81961 ggaacacatt gggttagaag aaatagcgga tcaatcgatt gacactcttt caggcggtca
    82021 actccaacgt gcgtatattg caatggtgct agcgcaagac acggattata ttttactgga
    82081 tgaacctttg aacaatctag atatgaattt tgcggttcaa atcatgcaga ttttaaaaaa
    82141 tttagtacaa gaaatcggga aaacaattgt tattgttctt catgatatca actttgctgc
    82201 aagttatgca gacgaaattg ttgcaatgaa agatggacag ttatttacgc aaggaacgac
    82261 ccaagaaatg ataaaaaaag atgtattgga tgaattatac gaaatggaca tacggatttg
    82321 tgagattgaa ggccgcagat tctgtcttta tttctaaaac taacattagg agagaagaga
    82381 tgaaaaaatt agtagtaggt atcttgattc tagcatcatt tggtttagca gcatgtggaa
    82441 atagcaacaa caccagtcag gcagacacaa aaaaaagcag cacacaaact gaaactacat
    82501 tgacgataac agatagtaat ggagaccaaa tcgaggtgcc aaataatcca gaaaaagtcg
    82561 tcgtattcga caatggttct ttagatacga tggatgctct tggtgttgga gataaggtag
    82621 ttggagcagc tacaagcagc cttcctgagt atctttcatc ctataaaaaa gtagaatcag
    82681 caggtggaat aaaagaacca gacttagaaa aaattaatca gcttcagcca gatctaatca
    82741 tcatttctgg ccgacaaaga gattttcaaa aagatctaag tcaaattgct ccgaccattt
    82801 tcctttcttt agatgcgaaa aatccatggg aatctttcca gcaaaatgtc actgctttag
    82861 gggagatctt tggtaagcaa gaagaagcta aaactcaatt agaggaatta tctagtgcaa
    82921 tcgatcagac gaaaaagaaa gcagaagcta ctgacaaaaa agcactagtc acacttgtga
    82981 atgaagggca attatcagcc tacggatctg gttctagatt cggtttcatc catgatttat
    83041 ttggctttga acaagcagat gatcaaatcg aagcatccac tcacggtcaa agtgtttctt
    83101 atgaatatgt gctggaaaaa aatccggata tcttatttgt agtagacaga acaaaagcta
    83161 ttggtggaga cgacagcaaa gatgatattt ctgccaatga actggtagca caaacgaatg
    83221 ctggtaaaaa tcagcagatc atctcccttg aaccagatgt ctggtattta agcgggggcg
    83281 gtttagaatc aatgaaactg atgatcgaag atgtgaatca agcatttaaa tagcataaat
    83341 aacagaggat taaactctca tactatgtaa caataatgtt tcttacattc ttaaatagca
    83401 agagcctatc ctcaaagaag ttatcaaaaa ccatccgtaa aatcgtattg atgattttac
    83461 ggatggtttt tatttatttg agaaatcttt tttcaacgtg aattcattat ctacatcata
    83521 cgggttgatt ctagaatggg gagtggcaaa aaatagtgtg atccattttt tcagcatcaa
    83581 gatcgcctcc tttgatttga atcaaaggta caaagcgaaa cttagataaa acttaaattt
    83641 agatattttt attttgtacc gatctcttct ttaaacgatg ttccatctgc tgcttctcgg
    83701 caataagtcc actagactag aaaatatgag aagctatttt ctgtccagcg ttcttattac
    83761 tcaaaacaaa tcgcagttgt cacaatctct tctaaacgat gttccatctg ctgcttctcg
    83821 gcaataagcc cactagacta gaaaatatga gaagctattt tctgtccagc gttcttatta
    83881 ctcaaagcaa atcgcagttg tcacaatctc ttctaaacaa tgttcaatca gctgaccttc
    83941 ggtattagct caaagcactg atttcacaac ctctatttag gcatgtgtct cagcaagcgg
    84001 ttgatagttg atgatctgca tttttcgata aaaatcggcg ggaagcttac tccaccgttt
    84061 tagtaattga tagaaataac tctcttctgc tttgatttta tactcgctta atatcaatcc
    84121 aaaactattc gttttttttg aagctaattt tttataaata tccaatgctt tggttttatc
    84181 ttcattgaca aagagtgttt ttacttcaat ataagaaccc tcgatatttt gtgtttcttc
    84241 gataaaatag atgtttttta tatattcctt catagtgatt cctccaaaga agtcttttat
    84301 ttgataagtt tactctaccg aagagttgtt aataatccgt gaacaaaaag taattctttt
    84361 tccaatagtt gttaaaggtt ttttattttt tatagtattt tttgttattt aagaaaggaa
    84421 taaggttaaa caaataacag gttgcttttt gggtcttttt ccgttcaaga aactgaacga
    84481 agaaaaggga aagttgtctc ttttgtgata agagaaatca taataaacga atgacttact
    84541 ttccaataaa ttgagaacag tcagaaccag acaaattagt tgcatctgat gaataaagtg
    84601 attattctat gacatgaggt gatacagatg aaattagaag tgacaaaaga agcacaagaa
    84661 gtattgaaga ataaattaga agcagacgat caacttttat tagatatcga aaacggtgac
    84721 ggtccatttg cagaaagcca agtcagttgc caattggata cggcatttcg attgatcatt
    84781 gtcaaaaaag atacacaaac agatctaagt ctttattctg tagtggctga tacaccagtt
    84841 ggaccaatca aaatcaaaga cagtgcaata ctttacatgg atgatccatc cacacttgct
    84901 ttagaaccaa cttataatag tttacaatta aaaggaccaa gcggcttgag aaaaggcaac
    84961 ttgcaagttg ttcgaaaaga ctagagggat aaaatgggaa aattggcgat catcagcgac
    85021 ctacatgtgg acatcaataa attcggcgaa tcagagctga tgcagctttg gcaagttttg
    85081 caaaagcaca agatcactcg gcttcatcta gccggagata cggctaataa agtagaccgt
    85141 tgcctagctg ttgtcgaatt tttcgtcaat aaaggattat ctacgacatt tcatttcggc
    85201 aatcacgagt tggcagatgt gcccaatgaa cagatgatgg accattttcc agacccacat
    85261 tttttaaatg aacggtatat tgctttaaat gagcagaccg ttcttttagg gatgaatggc
    85321 tggtacgact atcagttttc cgaattgaaa gattacgagg caatcgtacg aatgaagcgt
    85381 ttgtattggt atgatcggtt catccagcgt gggaaaacag atctcgaggt caatgcagaa
    85441 atgcttgcag ctgcaaaaaa tttgctagac cagctggaag caaaaaaact tgaggtgatt
    85501 ttatccactc atttcgttcc taaacgggca tttatcatgt atcaatctgc tccttatgag
    85561 cgttggaaca aattaaatgc atttttagga tcagaatcat tcggagaatt acttgaccgt
    85621 tattcaaata tcaaacaagt agtttttggc catacgcatc gtcgctttga agataaatcc
    85681 atcggtcaca cgatttacag ctgcagacct tttggttatt attatgaatg gcagctgacc
    85741 cgagattttg tcttgaaaga acagttgcta gacagctatg atcctatgaa attacgtgtc
    85801 ctcttgcgtg cccatcaccc agcttttcag gcctatcaaa cacaacattt gcaagaggaa
    85861 tttgaacaag cgatgacaat cgttccgtat tgagacagca ttagtaatgt gtaaaagaaa
    85921 ataccttgta aaacataagg ataagtaaga gcagtagatc catttatcgt ggatatgctg
    85981 ctttttttgc ggaaaataat cagcgaatgt ttatttgatc ggatgatttg taactcgcag
    86041 agtactagat gcaagcgtgt attctttttt tgaacgataa tcacaaaaaa aaatataata
    86101 tacatttttt atttaattat aattaatatt gattgaagtc taggcagtca agtcgagagt
//
LOCUS       DAFKHN010000004        59805 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFKHN010000004 DAFKHN010000000
VERSION     DAFKHN010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.004"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(233..1081)
                     /locus_tag="LY912_000262"
     CDS             complement(233..1081)
                     /locus_tag="LY912_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBM6953988.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="LY912_000263"
     CDS             complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="LY912_000263"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBM6953989.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3582..3761)
                     /locus_tag="LY912_000264"
     CDS             complement(3582..3761)
                     /locus_tag="LY912_000264"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBM6953990.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="LY912_000265"
     CDS             complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="LY912_000265"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBM6953991.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGVKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5909..8188
                     /locus_tag="LY912_000266"
     CDS             5909..8188
                     /locus_tag="LY912_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBM6953992.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETEIDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8281..8928)
                     /locus_tag="LY912_000267"
     CDS             complement(8281..8928)
                     /locus_tag="LY912_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6953993.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNNVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9107..9826)
                     /locus_tag="LY912_000268"
     CDS             complement(9107..9826)
                     /locus_tag="LY912_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6953994.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9957..11108)
                     /locus_tag="LY912_000269"
     CDS             complement(9957..11108)
                     /locus_tag="LY912_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBM6953995.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKTTGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTYSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDVGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11325..12065)
                     /locus_tag="LY912_000270"
     CDS             complement(11325..12065)
                     /locus_tag="LY912_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBM6953996.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEIFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12069..12425)
                     /gene="rsfS"
                     /locus_tag="LY912_000271"
     CDS             complement(12069..12425)
                     /gene="rsfS"
                     /locus_tag="LY912_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBM6953997.1"
                     /translation="MIDSKEQLKIAVEAADSKRAEDIIALDIRNVSLLADYFMICSAN
                     SERQINAITEEIIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERSFYNLE
                     KLWSDAPLVDLSEWLD"
     gene            complement(12449..13042)
                     /gene="yqeK"
                     /locus_tag="LY912_000272"
     CDS             complement(12449..13042)
                     /gene="yqeK"
                     /locus_tag="LY912_000272"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBM6953998.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13026..13676)
                     /locus_tag="LY912_000273"
     CDS             complement(13026..13676)
                     /locus_tag="LY912_000273"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBM6953999.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="LY912_000274"
     CDS             complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="LY912_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBM6954000.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="LY912_000275"
     CDS             complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="LY912_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBM6954001.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15119..15646)
                     /locus_tag="LY912_000276"
     CDS             complement(15119..15646)
                     /locus_tag="LY912_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBM6954002.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15873..16658)
                     /locus_tag="LY912_000277"
     CDS             complement(15873..16658)
                     /locus_tag="LY912_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBM6954003.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRFDQHELLEKRYKRFRQY"
     gene            complement(16651..17520)
                     /locus_tag="LY912_000278"
     CDS             complement(16651..17520)
                     /locus_tag="LY912_000278"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBM6954004.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHML
                     LELHTQKGWIDRG"
     gene            complement(17521..18900)
                     /locus_tag="LY912_000279"
     CDS             complement(17521..18900)
                     /locus_tag="LY912_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBM6954005.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDHF
                     GNVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18908..19327)
                     /gene="fabZ"
                     /locus_tag="LY912_000280"
     CDS             complement(18908..19327)
                     /gene="fabZ"
                     /locus_tag="LY912_000280"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBM6954006.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19352..19828)
                     /gene="accB"
                     /locus_tag="LY912_000281"
     CDS             complement(19352..19828)
                     /gene="accB"
                     /locus_tag="LY912_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBM6954007.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPETMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19831..21066)
                     /gene="fabF"
                     /locus_tag="LY912_000282"
     CDS             complement(19831..21066)
                     /gene="fabF"
                     /locus_tag="LY912_000282"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBM6954008.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIIGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21085..21822)
                     /gene="fabG"
                     /locus_tag="LY912_000283"
     CDS             complement(21085..21822)
                     /gene="fabG"
                     /locus_tag="LY912_000283"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBM6954009.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21834..22751)
                     /gene="fabD"
                     /locus_tag="LY912_000284"
     CDS             complement(21834..22751)
                     /gene="fabD"
                     /locus_tag="LY912_000284"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBM6954010.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22858..23082)
                     /locus_tag="LY912_000285"
     CDS             complement(22858..23082)
                     /locus_tag="LY912_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBM6954011.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23135..24097)
                     /locus_tag="LY912_000286"
     CDS             complement(23135..24097)
                     /locus_tag="LY912_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBM6954012.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24107..24547)
                     /locus_tag="LY912_000287"
     CDS             complement(24107..24547)
                     /locus_tag="LY912_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBM6954013.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24853..25818
                     /locus_tag="LY912_000288"
     CDS             24853..25818
                     /locus_tag="LY912_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBM6954014.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRAQLPDLQ
                     EMTFEQKKKELQGLFQGQNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKHFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMIASADVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQSEIELLNKKEAEKQLN"
     gene            complement(25875..26105)
                     /locus_tag="LY912_000289"
     CDS             complement(25875..26105)
                     /locus_tag="LY912_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBM6954015.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26191..27078)
                     /locus_tag="LY912_000290"
     CDS             complement(26191..27078)
                     /locus_tag="LY912_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBM6954016.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27167..28390)
                     /locus_tag="LY912_000291"
     CDS             complement(27167..28390)
                     /locus_tag="LY912_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBM6954017.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28407..29453)
                     /locus_tag="LY912_000292"
     CDS             complement(28407..29453)
                     /locus_tag="LY912_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBM6954018.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYSIRVPIQAISNGIDLEKYRPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29617..31344)
                     /gene="ptsP"
                     /locus_tag="LY912_000293"
     CDS             complement(29617..31344)
                     /gene="ptsP"
                     /locus_tag="LY912_000293"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBM6954019.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(31344..31610)
                     /locus_tag="LY912_000294"
     CDS             complement(31344..31610)
                     /locus_tag="LY912_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBM6954020.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            32089..34323
                     /locus_tag="LY912_000295"
     CDS             32089..34323
                     /locus_tag="LY912_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBM6954021.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34471..34791
                     /locus_tag="LY912_000296"
     CDS             34471..34791
                     /locus_tag="LY912_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBM6954022.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34996..35220)
                     /locus_tag="LY912_000297"
     CDS             complement(34996..35220)
                     /locus_tag="LY912_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBM6954023.1"
                     /translation="METEWQIRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35418..36998)
                     /locus_tag="LY912_000298"
     CDS             complement(35418..36998)
                     /locus_tag="LY912_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBM6954024.1"
                     /translation="MNNPELKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37399..38775)
                     /locus_tag="LY912_000299"
     CDS             complement(37399..38775)
                     /locus_tag="LY912_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBM6954025.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38903..40021)
                     /locus_tag="LY912_000300"
     CDS             complement(38903..40021)
                     /locus_tag="LY912_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBM6954026.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            40163..40443
                     /locus_tag="LY912_000301"
                     /pseudo
     CDS             40163..40443
                     /locus_tag="LY912_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(40521..41054)
                     /locus_tag="LY912_000302"
     CDS             complement(40521..41054)
                     /locus_tag="LY912_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBM6954027.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41148..42326)
                     /gene="mutY"
                     /locus_tag="LY912_000303"
     CDS             complement(41148..42326)
                     /gene="mutY"
                     /locus_tag="LY912_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBM6954028.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42319..43116)
                     /gene="recX"
                     /locus_tag="LY912_000304"
     CDS             complement(42319..43116)
                     /gene="recX"
                     /locus_tag="LY912_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBM6954029.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNRGKSQKELLRKIQQTLMTKGFSQEVIQQAMADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43223..44605
                     /gene="rlmD"
                     /locus_tag="LY912_000305"
     CDS             43223..44605
                     /gene="rlmD"
                     /locus_tag="LY912_000305"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBM6954030.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMICEINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44779..45357)
                     /locus_tag="LY912_000306"
     CDS             complement(44779..45357)
                     /locus_tag="LY912_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBM6954031.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45679..46149
                     /locus_tag="LY912_000307"
     CDS             45679..46149
                     /locus_tag="LY912_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBM6954032.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(46257..47483)
                     /locus_tag="LY912_000308"
     CDS             complement(46257..47483)
                     /locus_tag="LY912_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBM6954033.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(48237..48437)
                     /locus_tag="LY912_000309"
     CDS             complement(48237..48437)
                     /locus_tag="LY912_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBM6954034.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(48571..49179)
                     /locus_tag="LY912_000310"
     CDS             complement(48571..49179)
                     /locus_tag="LY912_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBM6954035.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(49264..49734)
                     /locus_tag="LY912_000311"
     CDS             complement(49264..49734)
                     /locus_tag="LY912_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBM6954036.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(49782..50696)
                     /locus_tag="LY912_000312"
     CDS             complement(49782..50696)
                     /locus_tag="LY912_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBM6954037.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            50842..51645
                     /locus_tag="LY912_000313"
     CDS             50842..51645
                     /locus_tag="LY912_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBM6954038.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            51823..52770
                     /locus_tag="LY912_000314"
     CDS             51823..52770
                     /locus_tag="LY912_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBM6954039.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(52838..53131)
                     /locus_tag="LY912_000315"
     CDS             complement(52838..53131)
                     /locus_tag="LY912_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBM6954040.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(53159..53824)
                     /locus_tag="LY912_000316"
     CDS             complement(53159..53824)
                     /locus_tag="LY912_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBM6954041.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(53964..54596)
                     /locus_tag="LY912_000317"
     CDS             complement(53964..54596)
                     /locus_tag="LY912_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6954042.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(54603..55670)
                     /locus_tag="LY912_000318"
     CDS             complement(54603..55670)
                     /locus_tag="LY912_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBM6954043.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(55667..56398)
                     /locus_tag="LY912_000319"
     CDS             complement(55667..56398)
                     /locus_tag="LY912_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBM6954044.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(56566..57045)
                     /gene="greA"
                     /locus_tag="LY912_000320"
     CDS             complement(56566..57045)
                     /gene="greA"
                     /locus_tag="LY912_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBM6954045.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(57181..58356)
                     /gene="mltG"
                     /locus_tag="LY912_000321"
     CDS             complement(57181..58356)
                     /gene="mltG"
                     /locus_tag="LY912_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBM6954046.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            58521..59681
                     /locus_tag="LY912_000322"
     CDS             58521..59681
                     /locus_tag="LY912_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBM6954047.1"
                     /translation="MSKGKHRKKQKISISFLVILLLSVSFFSTGIIIGGQLTKIPHSQ
                     TYKAEPTQLTSNLTPDEQRLASKIDQLLQKSDYIGSIYVRKNNRVLLEKGYGYANLRV
                     KESNSPSIYYQIGSIQKAMTALLILKQIQAGKLTFDTKLAEFYPQIPGSQQITIKNML
                     YMRSGLHRTASPDKPMSDSEIIQFALHHLKLTDYDTYHYEPLNYTLLTGILIKLTNQP
                     YETLLKKEIIRPLHLEHTDFYDNVKNSPQHAVSYQMSATDDYSKALIEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGGIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVVAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVHLSN"
BASE COUNT        17325 a        12592 c        10075 g        19813 t
ORIGIN      
        1 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
       61 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
      121 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
      181 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
      241 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
      301 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
      361 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
      421 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
      481 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
      541 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
      601 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
      661 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
      721 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
      781 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
      841 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
      901 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
      961 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     1021 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     1081 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     1141 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     1201 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     1261 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     1321 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     1381 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     1441 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     1501 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     1561 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     1621 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     1681 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     1741 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     1801 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     1861 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     1921 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     1981 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     2041 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     2101 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     2161 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     2221 tagaccatca tgtgatgagg gcagttcatt ggacgaagaa caagcatttc gccatctccc
     2281 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     2341 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     2401 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     2461 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     2521 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     2581 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     2641 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     2701 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     2761 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     2821 tttgaaagaa cacggcgttc gattggcaga ttttctttga cgattttcat catttctgct
     2881 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     2941 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     3001 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     3061 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     3121 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     3181 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     3241 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     3301 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     3361 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     3421 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     3481 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     3541 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     3601 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     3661 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     3721 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     3781 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     3841 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     3901 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     3961 aaaaatacaa ataaagatgc caatcagtac agactgttta gctattctca tcgtatctct
     4021 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     4081 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     4141 aagtgctgga gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     4201 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     4261 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     4321 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     4381 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     4441 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     4501 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     4561 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     4621 tgcactagct gcatacagaa gtagctcttc tttttttact ccattgactg gctgaatcgc
     4681 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     4741 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     4801 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     4861 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     4921 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     4981 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     5041 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     5101 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     5161 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     5221 ctgatcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     5281 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     5341 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     5401 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     5461 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     5521 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     5581 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     5641 tcctctttta tgtaacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     5701 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     5761 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     5821 ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt
     5881 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     5941 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     6001 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     6061 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     6121 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     6181 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     6241 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgtgc
     6301 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaat
     6361 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggtcgtat
     6421 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     6481 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     6541 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     6601 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     6661 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     6721 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     6781 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     6841 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     6901 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     6961 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattgcc
     7021 tttacatcat agactctctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     7081 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     7141 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     7201 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     7261 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     7321 tctaacacga cataaaatca gcgagaccag atggcaggaa catttgacaa ctgttcgtac
     7381 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     7441 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     7501 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     7561 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
     7621 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
     7681 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
     7741 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
     7801 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
     7861 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
     7921 acaacaagtc cagctgattt taaatgagag tgactttatg aaacgttcca ttattttact
     7981 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
     8041 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
     8101 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
     8161 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
     8221 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
     8281 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
     8341 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
     8401 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
     8461 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
     8521 gtatgcacta tcgatcacat tatttttttt cgtgtctatc ttctcatttc tttcgataag
     8581 aattttttca ggacgatgct tcaagctcca ctctaatagt agaaagaaag cctccatccg
     8641 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
     8701 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
     8761 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
     8821 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
     8881 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
     8941 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
     9001 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
     9061 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
     9121 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
     9181 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
     9241 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
     9301 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
     9361 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
     9421 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
     9481 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
     9541 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
     9601 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
     9661 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
     9721 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
     9781 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
     9841 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
     9901 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
     9961 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    10021 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    10081 atagaaatct cttttttttc ttttaagaat cttcttccaa catcggtaaa tccaagtagt
    10141 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    10201 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    10261 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    10321 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    10381 tacggccaat aagattccca agtctgcagc gaataagttg aaagatcttc ttctgtctga
    10441 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    10501 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    10561 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    10621 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    10681 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    10741 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    10801 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    10861 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    10921 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctcgt
    10981 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttgt ttttcgtgcc
    11041 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    11101 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    11161 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    11221 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    11281 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    11341 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    11401 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    11461 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    11521 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    11581 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaatttc atctacttga
    11641 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    11701 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    11761 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    11821 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    11881 tctaaccctg tcactttata tccatctttt gcaaaggcaa ctgctaatgc tccagtaccg
    11941 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctagc
    12001 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    12061 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    12121 tccagattat agaaacttcg ttctggtgca tggaaaacat gtacgatcac atctccaaga
    12181 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    12241 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    12301 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaatgtctaa agcgataatg
    12361 tcttctgccc gttttgaatc tgctgcttca accgcaattt ttaattgttc tttactatct
    12421 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    12481 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    12541 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    12601 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    12661 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatttct gcatcggtga
    12721 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    12781 aattcaataa ctctggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    12841 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    12901 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    12961 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    13021 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    13081 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    13141 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    13201 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    13261 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    13321 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    13381 gtttcaatct gcaaaaaagg attgtcttcc acagctaatt ccaacatgtt gagtcgatgt
    13441 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    13501 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    13561 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    13621 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    13681 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    13741 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    13801 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    13861 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    13921 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    13981 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    14041 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    14101 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    14161 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    14221 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    14281 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    14341 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    14401 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    14461 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    14521 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    14581 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    14641 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    14701 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    14761 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    14821 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    14881 accacattga cgatcaatgc atctttctgc cctaattcat tcagtaagcg caaaaagtcg
    14941 tcatccgtta atgagacatc ttggatctca ttataatggc gtaatctgaa acaacgctga
    15001 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    15061 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    15121 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    15181 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    15241 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    15301 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    15361 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    15421 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    15481 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    15541 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    15601 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    15661 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    15721 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    15781 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaag cgagcaagac
    15841 cattctttac tctttgctta gttgttaaac acctaatatt ggcggaacct cttgtatcgt
    15901 ttttccagta attcatgctg gtcgaatcga acaagttccg tcaatctttc aatcaacgct
    15961 tttttcataa tgtgtgcgac tttatatcgt ggcaactgct cgccgttgaa cgtttcagga
    16021 ataactcgat caacgattcc taactcgcgt agttctggcg cagtaatttt catcaactca
    16081 gctgcttctg cggcgcgact accgtctttc cacaaaatcg acgcaaatcc ttctggagaa
    16141 agcacagcat aaatcgtttc ttccagcatc cagacttcat ccgctaaacc tagagcaagg
    16201 gcaccgccac ttccaccttc accaatgatg atggcgatga tcggtacctt taaatcagac
    16261 atttcgagca gatttctggc aatagcctct ccttcgccgc gctcttctgc tcctacaccg
    16321 caatatgcac ctgctgtatt gatcaatgta atcaccggtc tattgaactt ttccgcttgt
    16381 ttcatcagtc gtaaagcttt tcgatagcct tcaggatggg gagaaccaaa atttctgcgg
    16441 atattttcct gcagatcccg tcctttttga ataccgatca ctgttaccgg tttgccatct
    16501 aatcgagcga ttccaccaac aatcgcttcg tcatctgcaa acaaacgatc accatggcat
    16561 tcctcgaaag aatcgaagat ctcttcaaaa aaatccaagc ttgtccatcg ttctttagct
    16621 cttgctaact gaacgacatc atgtgctgtc ttatccacga tctatccatc ctttctgtgt
    16681 atgcaattca agaagcatat ggattttctg cttcaattcc atgcggggaa caatctgatc
    16741 gacaaaacca tgagataata agaattcagc cttttggaaa tcttctggaa gttcctgctt
    16801 gatcgtctgt tcgatgacgc gtcttccagc aaaaccgatc aagctttggg gttctgctag
    16861 aatgatatcg ccttccattg caaaactggc agttactcct ccggtcgtcg ggtccgttaa
    16921 aacagttaga taaaaaagac cttcattgct atgccgtttg acagcagcag agatttttgc
    16981 catctgcatt agagaaaaga ttccttcttg catccgtgcg ccacctgaag ctgtgaacaa
    17041 gacgactgga agactttcct ttgttgctcg ttcgaataat ctggtgatct tttctccgac
    17101 aatcgttccc atacttccca tgataaaatt aggatccatc actccaataa tgaagggaat
    17161 cccttgaatg gttgctttac cagtgaggac tgcttcatga agtcctgttt tatcttgcat
    17221 ttttttaatt ttttccgtat attcgggaaa tgctagcgga tctttggtta caagatccgt
    17281 atcccattct tcaaaacttt tttcatcaat aatcaaagct agacgctgcc atgcaccgat
    17341 tcgaaaagcg tatccgcaat gagggcatac tttttcttca ccgatgtctt tcgtataaag
    17401 gatatgtttg caatttggac actttgccca catgttatca ggaacagatg gcgagttagc
    17461 aggtttgctc tctctattag gattgatccg aatatatttc tttttcttaa acagagccat
    17521 ctatgcgcct cctatctccg tttctggtgt ccaattcggt aaaaattctt cttgtaaaaa
    17581 tgctgtgctg taatcacctg ctatgactgc agggtgacta atcaaatcca tctgaaattc
    17641 tgcgttcgtg atgattcctt ctgtgataaa ttcacttaag gctcgctgca tcttcattaa
    17701 tgcttcaaaa cgcgtatttc catggacgat tatttttgca atcattgaat cataatatgg
    17761 cgggatcgta tatcccgggt aaactgcact gtctacccgc agtcccatcc cacctgctgg
    17821 aagcagtaag ttttggatct tccctggaga aggagcaaaa tggaaagcag gattttctgc
    17881 attaatccgg cattcgattg cgtgtccttg gaatactact tcttcttgac acacattcaa
    17941 aggctcaccg gctgctatct ccacctgttt ttttactaaa tcgattcctg tgaccatttc
    18001 tgttactgga tgttccactt ggattcgagt attcatttcc atgaaataaa aatcgccttc
    18061 ttcatccatc agaaactcga tcgttccggc attttcataa ttgactgctt tagctgctcg
    18121 aacagcagcg tctcctagtg cttctctttt tgtttgtgag atcactacag aaggagattc
    18181 ttccagtact ttttgattat tacgttgcaa agaacaatct cgttctccta aatgaatgac
    18241 attgccaaaa tgatcaccta aaatctgaac ttctatatgg cgagcaggat aaatgatttt
    18301 ttccaaatac atatcatcat ttccaaatgc cgctgctgct tcttgctgag ctgaagaaaa
    18361 atgctgtggg agctcttctt ttgattgaac tttccgaatg cctttcccgc caccacctgc
    18421 agctgctttc agcatcactg gataaccaat tctgtctgct atttccaatg cttcttctac
    18481 tgtagataat acaccagtac ttcctggaat gactgggaca tttgcttctt gcatcaattg
    18541 acgcgcattg atcttatttc ccattgcatc gatcgttgca cttttaggac caataaatgt
    18601 gatattgcac tcttcacaca tggaggcaaa tcggctattt tcagataaaa aaccaaatcc
    18661 tggatgaatt gcttcggctt ttgtcacgat tgcagcgctc agtacttcct gaacattcag
    18721 atatgaatca acggcttttg ccgggccaat gcagattgct tcatctgcta actgtgtatg
    18781 aagtgcttcg gcatctgctt ctgaatatat cgctacggtt tggatcccta gttcgcggca
    18841 tgcacgaatg atacgtacag cgatttcacc gcggttagct atcaatactt tagaaaacat
    18901 atttcaccta tccaatcata aaggttaatt ccgcttcggc tactttttta ccgtctactt
    18961 tagcgattcc tttgcctatt ccggctgaag ctttcacttt caatatctca acttcaaggt
    19021 ataaggtatc tcccggtgta actttcttac ggaattttgc tttgtccaat ccgccgaaat
    19081 aagccgtctt tcccttgaat tgttcaagag aaagtaatgc aactgctcct gcttgagcca
    19141 tcgcttcaac aattaatacc cctggcataa caggttcttc tggaaaatgt ccttgaaaaa
    19201 agggctcatt gatcgttaca tttttcttag caacgatccg ttctccttca accatttctt
    19261 ccactcgatc aatcaaaagc attggataac gatgtggaat gatttctttt atttcttgta
    19321 tgttcattga tttccctctt tcctgctttg cttatttttg ctgaatccta aagagtggct
    19381 gtccatattc gacaactgac tcgttttcta caaggatttc tgtgatcact ccgtcggcct
    19441 cactagttat ctcattcatc agtttcatcg cttcaataat gcagataact tctcctttgg
    19501 caacttgatc acctactttt ttgaaagctg gtttgtcggg cgccggttgc agataaacga
    19561 ttcccacgat tggcgaaaca acctcgattc catcaaatac tgccgattct ttttctttca
    19621 ttgtttctgg agcagttgtt gcttgttcag gtatgacatt gactggctcc gaaactggca
    19681 acgtttcgtt tgtttgaacc atattcatgc ctcgacttgt tttattttta ttcatataca
    19741 attcaaattg accttcacgc aaatcgaatt ccgttagcga ggattgatca aattgactga
    19801 ctaattctct gatttcattg atatccaaaa ttattcctcc cagcgtttca tgcacagaac
    19861 cgcattatgt ccgccaaacc ctaatgaatt actcattgca taagtaaaac ttgcaggttt
    19921 gctttcgttt ttgacaactg tcaagtcaat ctcaggatct tgtttttcta cattgatcgt
    19981 aggtgggata aattgatgtt ctaatgccag caaagttgcc aaggcttcga tcccgccggc
    20041 tgctcccaat aaatgtccag tcatcgattt cgtgctgctg acgtaagtat ctctgaaatt
    20101 ttcacctaat gcgatttgga ttgcttttgc ttctgcctgg tcattggctg gtgtacttgt
    20161 tccgtgagca ttgatatatc cgacttgttc cggctgtaca ccagcttctt ccatcgcaag
    20221 cttcattgct ttagacgcac cagaaccatc tggagtagga gctgtcatat ggtaagcgtc
    20281 acagtttgca ccgtatccaa tgatttctcc atagattttg gcaccgcgag cttgtgcatg
    20341 ttctaaagat tcaagaacta gaacacctgc tccttcaccc atcacaaaac catttcgatt
    20401 ttcgtcaaac ggaatcgaac cacgattagg atcagttgat tctgagagtg ctgttaaagc
    20461 tgcaaatcca gcaatcccca tctcacaaat cgttgcttct gttcctccag caagaatgac
    20521 atcagaatag ccatgtttga tgttacggaa tgcttcccca attgaattcg ttccgctagc
    20581 acaagctgtt acgatagctg tacaaatacc ttttgcacct acgcgcaaag caatatttcc
    20641 agctgccatg ttggcaatcg ccattggtac gaacattgga gaaactcgtt ttgcaccttt
    20701 ttcatgtaga cgaataactt ggttttcgat tgttggaaga ccaccgatcc cagatccgat
    20761 gatgacgcca aaccggtctt gattcatttt ttctttatct aaaccgctca tctccattgc
    20821 ttctaaagca gcgtagattc catagatcga aaacatatcc attcgtttgc tatctttttt
    20881 aataaaatat ttatcgtaag ggaaatcttt gacttcaccc gctaaggtaa tccctgtttc
    20941 tgaagcatca aatttagtga tcggtgcgat gccattcgtc ccctctttta agctattcaa
    21001 aaagctgtct gcgtcatttc caataggtga agtgactcca tagccagtaa ttaccactcg
    21061 attcatttgt ttgctctcct tttcttatcc gtgcatgacc aatccgccat cgacattgat
    21121 gacttgtccg gtgatatatg gattttgtgc taagaaaact gctgtttgtg caatatcttc
    21181 tacttgtccg aaacgctgca tcggaatttg cttttccgct tgttccttga ctttgtctgc
    21241 taaaacttcc gtcatatcag ttgtgatgaa tcctggcgca atggcattac atgtaatgcc
    21301 tctagttgca gcttctcgtg ccacagattt tgttaatcct actacgccag ctttactagc
    21361 tgcataattt gcctgaccaa tatttccaat caacccagat acactagaga gattaatgat
    21421 ggccccttct cgctgcttca tcattttttt caatacgtgc tgcgtcatat tgaaggttcc
    21481 aatcaaattg atatcaagac attttttgaa atcttctgca tccattcgca tcacaagttt
    21541 gtcatttgtg attccggcat tgtttactaa cacatggatc gatccaagct tttcttctgc
    21601 ttctttgatc atttgtcccg ctttctcata atcagagatg tcaccggaaa ctcctacgca
    21661 ttttacaccg aatgcttcga tttcttctat cttttctttt ggaatctctc cgcgaccatt
    21721 caaaatgata tttgctccag cttttgcaaa agctaaggcc atcgctttgc cgattcctct
    21781 tgtactacct gtgataaata cattttttcc ttttacatcc ataacgttcc tccttatagt
    21841 attgctattg tttcatcaaa tgtctgctta ttctcaacac gcagaactgg tattgtttta
    21901 tcgatttttt tcataaatcc gcttaatact tttccggggc cgacttcgat gacttgttcg
    21961 atgccgattg tttttaactt atggatactc tcatagaaac gaacaggttg catgacttgc
    22021 tgttcaagta gtcccgcgat tgtttctttc ttcattattt ccgttgttgt gttgcttatg
    22081 ataggaaaag aaggttcaga gaattgaatc tgacttaggt ccttcgccag tttttttgct
    22141 gccggttcta aaatagctgt atgaaaaggc ccgctgacat ttagagggat cattcttttg
    22201 aacccttttt cttttaatag taaaacagct tcgtctactg ctttttcttc gccaccaatc
    22261 acgatctgct gaggtgtatt ataatttgca ggagatacga tgccgtactt gctagcttca
    22321 tgacagcttt cctcgatcgt ttcaatcggc gcattcatca ctgcaaccat tttcccgctt
    22381 ccagctgggg cagcttctgt catataagcg cctctttttg ctactaacgc aactgcttca
    22441 gtgaaggata gcgcattact agctactaat gccgaatatt ctcctaaact cagtcctaaa
    22501 gctgcatctg ggatgattcc atgctccttc aataagcgat aatacgcgat gctgactgtt
    22561 agaatagctg gctgtgtata ttgcgtctga tccaaacgtt cattttctgt aaagcaaagt
    22621 tcagccatat cgtagccgag aatctcactt gcttcatcaa atgtctgctt tacaacggct
    22681 tcttcatata aatcttttcc cataccttga tattgtgcac cttggccact aaataagaat
    22741 gctgttttca tgtttttctc caatatatcc agaatatatg tttgattctt cctattcaaa
    22801 aaggccgaga cattcctatt tcaggaaatg tcccagcccc caacctaatt ttaatgatta
    22861 tgcagtttgt ttttctacgt aagtcactaa atcttgaacc gttttgattc cgtcttctgt
    22921 ttcgattttc acgtcaaatt catcttcaat ttcattgatg atttggaata aatccaagct
    22981 gtcagcttct aagtcttctt ggatgtcagt agtcaatttg atttcttcag tttcttttcc
    23041 taattcttct gcgatgattt cttgaatttt ttcgaatacc ataataatat attcctccga
    23101 tattgtttgc tttttatttt tataatttaa cagtctacaa ctccatgaga atacttcccc
    23161 atgttaaacc tccgccatag cctgtaaata ttactttctg ctgttttccc aaggtgatct
    23221 ttccactaga aactgcttca tccaataaga tagggatgct tgcagcagat gtattcccat
    23281 atttatccat attggtcagg aacttttctt gcggcatctt tacttttcgg gcaattttct
    23341 caataattct gaggtttgcc tgatgcaaaa gcagataatc aactggtttg tctttcatga
    23401 cttcttggat attgtttgca acgtctcgta cggcaaaatc aaaaatatct ctgccagtca
    23461 tttgcaaata atacgaacct tctgaatctt ctgaatagaa cggattttta ttttgctggt
    23521 agccagcggt caatgagcta cttctggtac cgtcagctgc taatttttct ttcagcaatt
    23581 ttttctgtgg attcgcttct aagagaatcc cacctgctcc atcgccaaac aacacagcag
    23641 tcgtacgatc agaccaatcg attagcttag atagtgtttc accaccaatc actagtccct
    23701 tagttgagcc gcagcggatc attttttcag ccatgcttaa cgcataaaca aatcctgagc
    23761 acgcagcact gatatcaaaa gcgatagcat gagttgctcc caatttccct tgtacttgtg
    23821 ctgctacaga tggcgtcgtg taatcgggcg acattgttgc tactaaaata aaatccaaat
    23881 ctttagggtt tagatttttc tgttttatca atttttccgc cactaaaatg cataaatcag
    23941 aagtctcctg atttgttaca catcttcgtt cacgaatacc cgtccttgac gaaatccatt
    24001 catcagaggt atccatcatc ttggaaagat cattattagt aataatcttt tcaggaagga
    24061 cgctggctgt tgcagtaatc attccaaatt gttccattaa atatcctcac ttatagtctt
    24121 gcaagaagtc gtgcaagttt ttcagtgcat ccagcaaggc atgctgttcc tccgtagcca
    24181 ttccgtctaa gatgttcttg accatttcac gatgaaaatg ctgatggacc cgaaatagta
    24241 actttccttt tttcgttagt cccaacttta caacgcggcg gtcatcttca ctgcggatac
    24301 gttcgacata gccttttttt actaacttgt taatagcagt ggtcaaggtc ccaacagtaa
    24361 ttgatagttc tttggctact tctgaagttg tttttttctt gtacatcccg attgcctcga
    24421 tcgtgtgcat ctctgtgatt gacagatctt tgaattgaga ttttttcagc tcagactctt
    24481 cgattgtcaa aatatcattg aagacactaa caagataatc atttactgtt tttaaatctg
    24541 gttccatgtt ccaccgtcca ctaattagtt tgattatcaa atcttttgat gttcaaacta
    24601 tatcttaact tttttcaaaa tgcaacctta aaagatcatt tttttactat atgagctttt
    24661 tttaagattt tactcattta aaacaactga taaatcagca tttataattt cttttattag
    24721 aaaaatcatc tatctcacat attttgatta tcaaagtatt ttctgtgaac agaactatag
    24781 aattccttaa aacttgtcca ttatttcaaa atttgttata gtctttttat tcaaagcgta
    24841 aaaggagatc ctatgttaaa agaaaaaatg aaaactctcc ccatgctgcc gggtgtctat
    24901 cttatgaaag accgtgatgg taaggtcatc tatgttggta aagcaaaacg gctcaaaaat
    24961 agagtaagca gctattttca tcagaataaa cagcattcaa aaaaagtatt acgtatgatt
    25021 catcatataa cagattttga tttcgtcgta gtagacacgg aattagatgc tttattgctc
    25081 gagtgtcaat tgatccaaca ttaccgtcct ttttataacc gacaaatgaa ttatttcagt
    25141 aattataatt atgtacatat taccaataag ggatttgtat taacagatac tcctacggct
    25201 cgaacatacg ggccttttcg tctctataaa aaaatgccgt ctattttgcg tataatggaa
    25261 gaaacttatc aaatgccttg gttgtctgaa attagtttgt tagctttgcg agcccagctt
    25321 cctgacctac aggaaatgac ttttgaacag aaaaaaaagg aactccaagg gctgtttcaa
    25381 ggccaaaata aaaagctact aacttacttg aaaaaaagac aacaacattt catctatcag
    25441 ttgaatttcg aaaaagccgg tatgcttcaa aaagatatcg aattagttac ttattttatt
    25501 agacggatcc aggaacaaaa gcatttttta agaacaccat cgctcacctt cagcatgcca
    25561 ttagcagcag atgagagtca gaaaaagcac tacctcgttt gttatggtca acttgcagaa
    25621 acaatgattg cctctgctga cgtttctcct gacttctatt atgaaaagaa agaagctcat
    25681 ttatctttga aacgtcaatt gtcaaaagaa gaaatcgatc ctgtacaaat cttgatcagt
    25741 taccgcaaaa aattagaaaa agaacagtct gaaattgaac tgttaaacaa aaaagaagct
    25801 gaaaagcaac taaattagtt gcttctcggc ttcttttagg catcttcaac ttcaaatgtc
    25861 aattatccta aaatttattg gattaagtca tagatttcca tcgctacgat atcgatatta
    25921 tcaaattcgt attgctgatg agtatctgtt tcagttaatt caaatgtatc ggtcgcttta
    25981 tcataagtta ctgtacactt ctctacgcct tctttttcaa aacggcgaac ttgcagttca
    26041 ttatctgctg actcgaccat agcctccagt cgttttatga ttgcgactaa ttgtgaatgt
    26101 gtcatcggag gtcctccttt tcttatttct gttatattgt atcaaaagca tagcctactt
    26161 gcattgattt tctctaaaaa aactcgtttt ttatgatttt ttttctggta tttttccttc
    26221 aggccaccaa agtttgatca aagcttgggt tccgtcattc tcaaaacctt tatctgccaa
    26281 ctcttcatat agtttcaatg cttgggtagt tgctggcaat acaaggtcca ttttttctgc
    26341 ttcttctaat gcaatcttta aatctttgat aaaatgtttg acaaaaaaac caggtgtgta
    26401 atcttctttt aaaatacgag gagaataatt gcttaaagac cagttagctg cacttccacc
    26461 tgaaagcgtc tcaatcactt tctttaaatc aagtccgttt ttttgtgcat agacaagcat
    26521 ttccgtcatt cctgtcatcg tacctgcaat catgatctga ttagccattt ttgtatgctg
    26581 acctttccca gcagaaccat gcaatgtaaa tgtcgtacca aattctttga ataaaggcag
    26641 tacttgatca taaacggctt cttctccacc gaccatgatc gtcagtgtac cattctttgc
    26701 tcctaagtca ccaccggata ccggtgcatc taacgcatct gcgccttttt cttttgctgt
    26761 ttttgcaatt ttttctgcca ggcttggtgt acttgtagtc aagtcaacta aaatatgtcc
    26821 tgagatatct gcagaaaaaa tccccgactg tccatagtag atttcttcta catctttggg
    26881 gtaacctacc attgtaaaga gaatattact ttgttctgct accgcttttg gtgtatctgc
    26941 ccagatagct ccttctgtta ctaaaggatc agcttttgct tttgtccgat tatagacagc
    27001 tacttcgtgt cctgcttcta gtagatggcg tgcgacagca cttcccatga cgcctgttcc
    27061 gataaaacca agtttcattt tttcgacctc ctaaaaatca aaaatccttg cttctatgct
    27121 agtatacgct agaaacaagg attttttcat aaaaaatgtt tgaattttat cttttaaatg
    27181 aatttaattt tattttgatt cgttcaatcg agtcttcttc ttcttttctt cgcatctctt
    27241 cttcatgata aacaaccatg tcttgataaa attcgatcat agcttcgccg aaatgtgtag
    27301 atgaaatatc ataaagttta gcttctaaaa cttttggatc tttaggaact tcactggaaa
    27361 tataatcaat aagtgctggt gcaaagtctt cgtcggtttc aaaagttttc cctaatgaag
    27421 gatgatcaaa caatcggttc aaataagcat ttccttccac gacacaaggt gttccggctg
    27481 ccatcgcttc tgtataagta agcccttgtg tttctgaagt agaagcactg acaaaataat
    27541 ctgccgcttt ataataaagt gctacatcat tgttgtccac ttctcctgtg aactgcacaa
    27601 attcttctaa ctgcagttct gagatcaatt cctctaactc ttctacataa ggtccttttc
    27661 ctacgataac taatctggcg ttaggataag cggagatgac ctgaggaaac ccattaatca
    27721 aggcttggat atttttttca taagaaatcc tgcttaaaga aagaatcatc aaatggtttt
    27781 cctgaagacc tagtgactcc cttaatttgc tgatatcctg ctgagtgata tcagaacgtt
    27841 tgaatttttc aatgtcgata ccagtaggaa tcacgcgaag cggtgctatt acaccatagc
    27901 tacgtaatgt atcaataaca cgttcacttg gacaaactac acctgtcgta tgatttgcaa
    27961 ataatctaga caagtatttt acatgggatt gcctgatcac ttttccttta ccgatataat
    28021 gaaggtagtc ttcatacatc gtatggtaag tatggatcag aggtattttc aacttcttag
    28081 ctaccatctt cccaagtatc cctgctccga attctgtatg ggtatgaata agatctagtt
    28141 ctagttcttt ggcaaccaaa taagcatacc acatgcctct aacaacaact cttcgatcct
    28201 tgaaagaaat aaatggtaca cttggcattc gaatcacatc tttttccaac ttatccgcat
    28261 taggatcggt cgttgtaaaa atatagactt catgcccatg tctttctaat tcttgtttta
    28321 atgttttgat cgatgtagca actccgctga cttgcggaaa gtaggtatcg gtaaaaaagc
    28381 cgattttcat gtttttcgcc tccaaactag tccttgacct gatttacttt ttttaatttg
    28441 ctagagactt tttcattcag tacactttcg tatacatttt taagttcttc accgatttta
    28501 ttgatacttc gctcttttgc tgtttgataa ccggcttgtg tcgtactcgg tagttcttga
    28561 ttggtaatct gttggatcag tcggataaat tcttcgtttg tcttccccat atagcagttc
    28621 ttgctatctt ctaaccagcc attatacact ggaatatctc gaacaagtac gttttgtttg
    28681 cttgctaaag cttctaaaac aacgatccct tctgtctctt cataagaagg gaaaaagaat
    28741 agatctgcac ctgaatacgc accttctatg atctctccac gaatgtaacc aggaaacagg
    28801 acattttcag gatgatcttc ttttacaatt ttccggatgt tccgaggaat cgagtacatg
    28861 ggaacatgac caaaccaaat aaatgtgtat tcgggcatct tcttagcaat ttctacgaaa
    28921 tcaatgattc ctttacgttc gaaaaacaaa ccgacacaaa tgattacttt ttgatccgga
    28981 gacagtttga aatattctct gaacttttgt tctttcattg gatcagggcg atatttctct
    29041 aagtcgatcc cattggaaat agcttgaatc ggcacacgga tactatagct ttccaacaac
    29101 tgttttgaat aaggtgttgg cgtgatcaga tagtccgctt tttggtacaa tcctaccaga
    29161 tattttttta cgataggaga aagctggttc gatccgataa aggaatttcg gaaatcttcc
    29221 tctgtagaat gcgcatgata gacaactttt tttccttctc ttctggcttt attgaccata
    29281 ttatgactat tgattccgta tgtattgatg tgcaggatgt cataatcttc tttttcatct
    29341 agtgtataag agataccgac ttccgtcaga gcacgttttt gatgatcaag cgcacgcccg
    29401 attccagatt ttgcaagcat cttttcactt tcaaaatata ataatacctt caccttacgt
    29461 cccccttcac ttatatagta taacatagcc tacaaactgt cactcaaact taagccctat
    29521 ttttatctat tcttactgac aaaaacgttt tcttaaaaaa gaacaaaaaa actggcgtag
    29581 ctcttttaca agccacacca gcttttgata cgttgtttat tttacatatt catgaacaag
    29641 ttcaacgact tcttccatcg tatcgcattc tttcaatgca cgatcagcaa gttcagccat
    29701 tttcgctgtg tccaagcgtt tcattaaact acgcgtttta agaatagatg tcgcactcat
    29761 tgagaactca tctagaccca tacctactag caatggaaca gctgtttgat ctccagccat
    29821 ttctccacac atacctgccc attttccttc agcgtgtgct gcatcaatta catttttgat
    29881 caaacgtaaa attgatgggt tatatggttg gtacaagtaa gaaacgcgtt cgttcatacg
    29941 gtctgctgcc attgtgtatt gaatcaaatc gttcgtacct acagagaaga aatctacttc
    30001 ttttgcaaac ttgtctgcta agactgctgc tgctggaatc tcgatcatga tgccgacttg
    30061 gatcgtatca gatacttcct tgccttcact gatcaatttt tgtttttctt cttcaaagat
    30121 cgcttttgct gcgcggaatt ctttgagtgt agctaccata gggaacatga tacgtaagtt
    30181 accatgaaca gatgcacgaa gcaatgcacg catttgtgta cggaacattt cgtcgccttg
    30241 ttcagataaa ctgatacgca atgcacgata tcctaagaat ggattcattt catgaggtaa
    30301 ttgcagatat ggtagttctt tatctccacc gatgtccatt gtacgaacaa ctacaggttt
    30361 tccttccata ccttctaata cagctttgta agcttcatat tggtcatctt ctgttgggaa
    30421 gtctggagaa tccatataca ggaattcagt acggtacaga ccaactgctt ctccaccatt
    30481 attatggaca ccaactagat cttttggtgt tccgatgttt gcagctaatt caaaatgctt
    30541 gccgtcagct gtgacagttt ctgcattttt taatttttcc cattctgctt tttgtgctgc
    30601 gtaatctgca cctgcttttt caaattcagc tttttgttca tctgtaggat cgatgattac
    30661 atcgccttcg atcccgttga cagccaaaat atcgccttct ttgactttag cagtaatttc
    30721 ttttgtacca acgattgctg gaatttctaa agaacgtgcc atgatagcag aatgtgaagt
    30781 acgtccacca atgtctgtta caaacgcttt tacaaaattg cgatctaatt gtgctgtatc
    30841 acttggagtc aagtcatgtg caacaacgac cacttcttcg ttgatcattg atggatttgg
    30901 taaagtaacg cctaataagt gcgctaaaat acgtttagca acatcacgaa tatctgcagc
    30961 acgctcttgc atataagcat tatcttccat tgcttcgaac ataccgatat acatatccgt
    31021 tacttctttt agcgctgatt cagcatttac gctgttgtct ttaatatttt gcttgatttg
    31081 acctaccatt tctggatctg aaagaaccat caaatgggca tcaaatactt gcgcttctgc
    31141 ttcacctaag ctttgcgctg ctttttcacg aatttgctgc aattcttcag tagatttagc
    31201 taatgcagca tccaaacgag cttcttcagc cgcagtatct tctactgttg ccttactgaa
    31261 tgttaaatcc ggttgaacta gcaggtaagc ttttgcaacg gctacaccgt cactagcggc
    31321 aatccctttt agcatttcaa ccattattca gataagcctt ctttcttcat tgtttcaacg
    31381 attgctgcca ttgcatcagc ttcgtcagca ccttctgcag taatagtaac atcagaacct
    31441 tgacctacac ctaaagacat aacgcccatg attgatttca agtttactga tttaccttta
    31501 tactctaagt ttacatcaga gttaaatttg cttgctgttt gtactaatag tgtagctgga
    31561 cgagcgtgga tcccagtttc tgctactacg tgaaattctt tcttttccat attaatcggt
    31621 ctcctttaag tgagtgttgt ttttatgtga gggttttctt ttttagtaat tcagagaatc
    31681 ctaacaaatg ccaccctttc atctgtaaag attaacattt tttttcgtta gatacaacag
    31741 ttttcattca atttcagata aaagtattca aattattccg gattcttttt catccttttc
    31801 ttcacatttt ataacaaaag tgtttatttt ctttttcttg tcgctttctc ttctcctgac
    31861 gtttatcatt ctttcctttg accctctttg ttttcatatg aaacgaatta cttgcttccc
    31921 tttttatttt tagtataata agagtcaaag gtcaggaatg gtcaatagag atttcacctt
    31981 ttctacctca taaatctctt aaaaaactag gggttattct tttacctcat gaaaaacgag
    32041 atgtaaaata tggatgtacc catttttgtg aaaggacgtg aatgattcat gctttgtcaa
    32101 aactgcggca agaatgaggc aacgattcac ttgtatgcca ctgtcaatgg tcagcggaca
    32161 caactcgatt actgtcagag ctgttatcaa aaaatcaaaa atcaacaaaa tggaggtctg
    32221 actaatatgg cccaaaatga tccatttgga tttggcagtt tggacgatct tttccgttcc
    32281 atgtctcgcc aaatgcaaca gcaaggaaat tatgagcaaa caccaccaac acaatttggc
    32341 ggaaacaaca acttcaatgg tggtcagcca cctcaaggca atacagaagg tttattggga
    32401 gaatacggaa tcaatatcac agaacaagca cgacaaggtg atatcgatcc tgtgatcgga
    32461 cgcgatgacg aaatcaaacg agtcattgaa attttaaatc gccgaaccaa gaacaatcct
    32521 gtcttgattg gagaaccagg tgttggtaaa acagcagttg ttgaaggttt agcacaaaaa
    32581 atcgtagatg gtgatgtacc gcaaaaatta atggacaaag aagtcattcg tttagatgtc
    32641 gtatctttag tccaaggtac tggtatacga ggacaatttg aagaacgtat gcaaaaattg
    32701 attgaagaga tccgtcaagc agaaaatgtg atcctattca tagatgaagt tcacgaaatc
    32761 gtcggtgctg gttctgctgg tgatggaaat atggatgctg gtaatatttt aaaaccagct
    32821 ttagctcgag gagaattgca aatggttggt gctactacct taaatgagta ccgcatcatc
    32881 gaaaaagacg ctgctttaga acgtcgtatg caacctgtac gggtagatga accaactgtc
    32941 gaagaaacga tcagtatttt gaaaggtttg caaaaacgtt atgaagacta tcatcatgta
    33001 aaatatactg atgaggccat cgaagcagcc gcaactttat ccaatcgtta cgtccaagat
    33061 cgcttcttgc cggataaagc catcgatttg ctagatgaaa caggttctaa gaaaaacttg
    33121 acgatccaaa tcgttgatcc taaaacaatc gagaaaaaac tgcaagaagc agaagaacaa
    33181 aaagttttag cttctcgaga agaagatttc gaaaaagcag cttattatcg cgatcagatc
    33241 aataaacttc aaaaaatgaa agaacgtcag ctcactgaag aggaaacacc tgtgattacc
    33301 gaaaaagata tggaaaaaat cgttgaacaa cggacaggta ttccagtggg tgaattaaaa
    33361 gaaaaagaac agacacaact gaaaaactta gcagatgact tgaaagctca tgtcatcgga
    33421 caagataacg ctgtagatcg agtagcgaaa gcgattcgtc gaaaccgtgt tggattaaac
    33481 aaacagaatc gtccaatcgg ctccttctta tttgttggac caactggtgt aggtaaaaca
    33541 gagcttgcga aacaacttgc ctacgaacta ttcggttcac aagattcaat gattcgtttc
    33601 gatatgtctg aatatatgga aaaacatagt gtctctaaat tgattggttc tcctccaggt
    33661 tatgtcggat acgaagaagc tggtcaatta acagaaaaag tacggagaaa tccttacagt
    33721 cttgtcttgt tagatgaagt agaaaaagct catccagatg ttttgcatat gttcttgcaa
    33781 atcttagatg atggtcgatt gacagatgca caaggaagaa cggtcagctt taaagatacg
    33841 atcatcatta tgacaagtaa tgccggaact ggtaaagtag aagcaaacgt tggttttggt
    33901 gcggcacgcg aaggtgttac tcgttctgta ttgaaccaat taaacaacta ctttacacca
    33961 gaatttctga accgttttga cgggatcatc gaattcagtg cattatcaaa agaaaacttg
    34021 atgacaatcg tcacactaat gctagacgat gtcaaccaaa tgctggcagc acagcaactt
    34081 cacatcgaag ttcctacgaa tgtcaaagaa aaattagttg acttaggcta tgatccatct
    34141 atgggtgctc gtcctcttcg acgcacgatc caagaacaaa tcgaagatgg tatcgctgaa
    34201 ttttatcttg atcacccttc tatccatgag ttgaaagcaa aactggataa agatggaaaa
    34261 atcatcgtta cttctaaacc agaacgtttg gctaaagaat cagccgaaga aacggctgaa
    34321 taaatccagt tttatagcgt gagacggtat ttctttgaga aatgccgtct cattcttttt
    34381 tcagaaaagt caaaatactg ttcattttat aaaaaagaaa ttataataag agaaacaagc
    34441 aattaaaaat acataaaaga ggtgagcgcc atgaaattgg taaatgtaac aaacagccat
    34501 tcccgtcttg tattaaacca gcttgaaaac actgatgccc atctagtcaa ggtctacaca
    34561 gccggaaata ccactattgt ctacactgaa gcccctgaac ataatgaaat tctgctgatc
    34621 aatgacaaac gtaaaatcca gccgaaagaa atcgaagatg ctaaaaatta tttcttagat
    34681 aaaatcaaag acgccgttta ccacgaggat gaaatcaaag taatcgaatt ggcaggcctt
    34741 gttgaaatct cgattccaaa acatgaatta ggcgctacat tagccgtgta aacaaatttt
    34801 gaacataata attaaagagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
    34861 acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctaaa attcacgaaa
    34921 attgcttttc aaatttttgt gaattccagc ttatttcttg gagttaaacg cttctgtctc
    34981 agcctctttt tctttctagc tttttgattt ttctcttttc ttttgtactt ttctcttttc
    35041 attttcagtt ctacgcgtgt ctttattttt aactttttcc tctttatgga tgattgatcg
    35101 tactttttgt gcaatttgct cgtttttgtc ccagtctttt acatctaata atcgacataa
    35161 tcgtaacatc tcttcttttt tctgtttttt tctttcacgt atttgccatt ctgtttccat
    35221 gtgtcacact ctcctttctt taatcatatg tacgcaaaat aatttttata tttttttgat
    35281 tagacatttc tatgatttta atatagtaaa aagagccgtc acggaaaatc cgtcacggct
    35341 ctaaacaaaa tatgagaggc tgtttttgtt tggctattct tattacttga tgcagggcag
    35401 cttgtgtcaa gacttcttta catcaaactt tttaatttta cattaggata tttatccgca
    35461 aaccagcgtt ctgcaaattg gttctcgaat aagaacaatg gttggtcgaa acggtcacga
    35521 gccaagatat tgcgacttga actcatcttc tcatccaaat cttctggatc gatccagcga
    35581 gcgattttgt gtcccattgg agacatgatt acttcggcgt tatactcatt taacatacga
    35641 tattggaata cttcgaattg tagctgacca acagctccaa tgatatattc ttccgttaga
    35701 tatgttttat aaagctgaat cgctccttct tgaactaatt gatagattcc tttgtggaag
    35761 gatttttgtt tcatgacatt ttttgcagtc actttcataa acagctctgg agtaaatgaa
    35821 gggagttctt cataagcaac ttttagtttt ccttcgaaca atgtatcccc aatctgataa
    35881 ttgcctgtat catatacacc gatgatatcg cctgctactg ctttttcgac gttttctctc
    35941 gaatctgcca taaattgtgt gacattgctt aatttcagtt ttttatttgt acgttccaac
    36001 cagacatcca ttcctcgttc gaatgttcca gaacagattc ggacaaaagc gattcggtca
    36061 cgatgggctg gattcatatt tgcttggatc ttgaatacga aacctgaaaa ttcttcctca
    36121 taaggactta ccatctgatc atcttgtgtt ttgtgtccat aaggagctgg tgccaattca
    36181 acgaaagtct ctaaaaaagt ctgtacaccg aagttagtca atgcagaacc aaaaaatact
    36241 ggtgtctgat cgccacgagc aattttttct tgattaaatg catctccagc ctctttgatt
    36301 agttctactt cttctaagac ttgttcatat aaggaatttt cagttagagg atgattttcg
    36361 ggaagcagtc catcttcatc caattctact aatcgttcat cctgataatt ttccggacga
    36421 taaaactcta cacgattatg gtagatatca taaagacctt ctagcccttt acccataccg
    36481 attggccaat tcatcggata agattcgata tctaatagct cttctaattc ttctaacaat
    36541 tccaatggtt cacgaccatc acgatctagt ttgttgataa aagtaaatat cgggatgcca
    36601 cgttttttta caacttggaa taatttcttt gtctgtgctt cgatcccttt tgcactatcg
    36661 attaccatga ccgcactatc cacggccatc aaagtacgat aagtatcttc agaaaaatct
    36721 tcatgtcctg gtgtatccaa gatatttact cgtttccctt gataatcaaa ctgcataaca
    36781 gaactagtaa cagaaatccc acgttgtttc tcgatttcca tccagtctga tttggcaaaa
    36841 ttacctgttt ttttgccttt tacggtcccg gcttgacgga tagccccacc aaacaatagt
    36901 aattgttctg taatcgttgt tttcccagca tccggatggg aaatgatcgc aaaagttctg
    36961 cgattgtcca cttgttgctt taattctgga ttattcataa cctaactcca tttcttccat
    37021 tcaattattt atattttctc taggcacaga ttgtccgatc tcttaaagaa agacaatttc
    37081 atatagggct gtgacaaaag ccgtgtagca gtctcttttt ccgagtaaac ggcgttctag
    37141 agacagccta tcagcaataa gcccacccaa gccaaaaata cgaaaagctg tttttgcttg
    37201 gctgctctta ttacttaatg caggatagct ttttcacaac ctttgtcaac tactacaact
    37261 gaatcagtat agcatggatt catcgaatga aaaagccacc aaaccataag agtcaaatat
    37321 ttttttgtca gctgactaaa agaaaagacg tgttgcttgt ttattcaagc aacacgtctt
    37381 tcataaccaa gtttccaatt atcttcttgg ctcgtcatct tcgaattctt ttctgaagta
    37441 tcttcgttct tcttcaggtt ccgcttctgt ttcttccgga tcatgaaaaa tgacacggat
    37501 tttaaggatt cgagaacctt ccatttcttc agaaaccagc gtaatattat cgacatcaaa
    37561 cgataacttt tcgccttcat ccggaatcat gcctaatgct gtaatcaaat aaccagccat
    37621 cgtatctaca tcactcatat gcagatcact gtcaaaagct tcattgaact catcaatcag
    37681 catacgtcct tggatgatat attcgtgttc atcgattttt tcataaagat tctcaacttc
    37741 atctgattca tcatcgattt ctccgacgat ttcttctaaa aggtcttcta gtgttgctaa
    37801 cccaacgacg ccgccatatt catctaataa aatagccatc tgattctgcg tctttttcat
    37861 ttcatataac agatcatcaa taaagaccgt ttcaggaacg aataaaggct cctgcatgat
    37921 tttcttgata tctaaattat caaaaccgaa tttatgggca gcttttagta aattctttgt
    37981 atgaaggatt ccgactactt tatctttgtc ttcgttataa acagggattc ttgaatagtt
    38041 ttcggataaa acttcattca cattttcttc cacagtgtcg ttgatatcaa tcataaatgc
    38101 atccgttcgt gggaccatga cttctcgggc aactttcgta tcaagagaaa aaaccccttg
    38161 gagcatttct aattcttcat tattcaatac gccttcgttt tcaagcatat aacgcatttc
    38221 atctctggtc atttttgaat cttcatcatc aaaagtcatc ggcgtgatac gcgccaataa
    38281 acttgtggaa gcagaaagca gccagacgaa gggcttagct actacaccaa tcaagcgtat
    38341 cagccctgaa gtgaactttg cgacttcttc tgatttattt aaagcaatac gtttagggta
    38401 caattctcca aaaacaatcg atacataggt caaaatagcc agcacaatga tatttgcaat
    38461 attttttgcc gctgtgccgc cacctaatac cggagctaac cgttccgata aagtattagc
    38521 tagtgaagca ccagacaaaa tgttgaccaa agtgattcct acttggattg tcgataggaa
    38581 attatttgga ttctgcaata tttttaaaag cttttgagat ttcacatctc cttcatcagc
    38641 tttttgctcg attcgattct tattgatcga aacaacagca atttcggaag ctgctaaaaa
    38701 agcattgatc aatgtcaaaa cgatcaataa taaaatctgc gctaacagcg actgactctc
    38761 agggtcagca ttcataatcg cattctctcc ttataaaatt aatttttagt ttacgataga
    38821 aaaaaacgtg gcactatagc cacgttaaaa tggtatcaca aagcaatttt ctttgcaata
    38881 aaaacaagtg tactaaaact acctacgagg tcgtagcaat tttcttcttg ttttcatttt
    38941 gcttgtcttc tttgacgatt ttgattatat aggaaatgat cgtcttgcag attgcgtaaa
    39001 aaggaacacc taagaagata ccaagcaatc cggcaatatt tccagctact agaagaacga
    39061 taatgatcgt taatggatgg attttcagtg atttcccaat tacattagga taaatgatat
    39121 tcccatccaa ctgttggacg attagcacaa ccacacaaca aagtaatgct tttaccggat
    39181 cattgaagac tgttactaga aatgcaggtg ctagtcctag ataaggtcct aaatatggaa
    39241 ttaggtttgt caatcccgca atgaccccaa ataagaaagc ataatccaca ccaattacca
    39301 tatatcctaa aaatgtgaag gtaccaacga ataaacattc gattgcttgt ccgctaatgt
    39361 aattagccaa tgttttattc agttgcccca ataactccac aatttggttt cttctttttt
    39421 ctgggaaaaa ctgttggatg tttggcacta gtttttctcc gtctttcaac atatagaaca
    39481 agatgaatgg tgctgtaatg attactacgg ttgccgaagc gatcgttcca acgatcgaac
    39541 ctaaactatt ggatactcca ctaaggaatt gctgaatgat tgtcccgtaa gaaatgtcta
    39601 attgctcaaa atatttattg atatctactt ccttgaacaa aggcaattcg gctacctctt
    39661 ttaaccagct ttctacctgt ttgatgaaat caggcatatt agatgccaat gaggaaattt
    39721 gctgtactag acttgggatg acactaagta aaatccaaat aattgctgca actaaaagga
    39781 gcagcacaat tgcgacagcc catattcttt tgatttttgc tttcatcaac agcttgacaa
    39841 taggattcaa taaatagtaa agaaagcctg caatcagtac aggtgcaaat aacgtggaaa
    39901 aaaatgtccc gatcggttcg aaaataaagt ttatttctga tgaaatcatg atcaatgcag
    39961 ctatgatcaa taattcaagc gaccaaaaca ttagtttaga ctgtctaagt ttttcaaaca
    40021 atagatttcc tcctttcttt cttactagta tatattatat tcgttaaaaa ttcttttatt
    40081 ctttttttat ttttgaaaac ttgccatact ttttatttgt tttattttcc agtatactat
    40141 acgaaaggaa ggtggctaga ccatgaaagt tgtacaaaca aaagatacaa tgagcaatat
    40201 ttacttagat gctgtacgga tcaggcatca agtttttgta gtcgaacagg gtatgccttt
    40261 gtctcgagaa atagacaaag atgaagccca ttgtatccac ttcgtcctgt actcagataa
    40321 aaaagaaccg caaggaactg tacgtctttt gcctttagaa aacggaaaaa tgaaattaca
    40381 gcggatggcg atccttttga agatgctggc atgcctcata tttatatgaa aaagacttta
    40441 taaaaattta tttcgaaaaa agcaaaaaac agcaagcttt tgagaaaaat ctctcactgg
    40501 cttactgttc ttttttgtgt ttacttacgc gacaattgct tgtaacggtt ataccaaata
    40561 tcaatatagc cttccgagaa cgggccatct ccattattga tccagtcaac cagaatcttc
    40621 acattttctt ttaggatgaa gtcaatatcg ttcggataat tcatcatttt gctgtgcatc
    40681 tcatattcat cgacatccaa tagtcgtttc tcgccgtcag gaaatacctt gatatccaag
    40741 tcatagtcga tatatttcaa ggcctcatcg tccagcaaaa aaggtgaagc tagattacaa
    40801 taataggaaa cccccttttc tctgatcatt gctattacat tgaaccagta ttttttatga
    40861 aaataaacaa tcgctggttc gcgcgttacc catcggcgtc catcagattc agtgactaat
    40921 gtgtgatcat tcacgccgat catagagtgt tcgcttgttt ttaataccat ggtatctcgc
    40981 cacgttcgat gcaatttgcc gtcgtgcttg taactttgga tcgtcacaaa ctctccttct
    41041 tttggaactc ccatagcaac ccttccttaa gcagcatttt gtgctttgtg tttgggtgtt
    41101 cattacaccg acatcataat tattatatca ataaaaatga gctttgccta gaaaggattc
    41161 ctattgtttc gatttttctc taactgatct accagtttca tttggacctt aggaaaaacg
    41221 accgaatcaa atgcatcagg cttcaaccac ttcgaagttt tgttctcggt aaattcttgt
    41281 tctgctccct cggttgcccg tccgtaaaaa aggagaacat gccatttcag atgactaaaa
    41341 atatgagtaa cttctcctaa atgtcgtgtc tgccaaacaa agagttcctg cttttcaaat
    41401 gggagatttt gctcttcttc tgctactagg tcatcaaaca gatcgatttc tggctttgtt
    41461 tcccattctt ttttcaatcg ctcatactcc tcttgtgtca cttccatcat tggaaatgtc
    41521 cacatattcg ccagcaattt ttggctatct ctttcttcaa aataatacgc tccagaatga
    41581 ttttgaagag ccgcactgat ataataaacg tcttttggct ttgctttttt tgtttttaca
    41641 ggaaaactcg tttggattcc tcgtttgtta gctaaacaaa aggcttggat cggacaagtc
    41701 tcacactttg gagaagttgg tgtacagata gctgaaccta gatccatcat tgcttggttg
    41761 aattcacctg gatgcttttc atcaatgatt ttccgcatcg cttcatcaaa gattttcctg
    41821 ctagaagctt ttgcgatgtc tgcttcaatg caaaacaatc tgctgactac tcgcatcacg
    41881 ttgccgtcaa ccgcgggttc tggaagtcca aatgcgatac ttgcaatcgc gcctgtcgta
    41941 tatggtccta ttcccttcaa tgagctaatt tcttcaggcg tttgcggcat ttccccatca
    42001 aattctgaca tgatctgttt agcagcagct tggatgttcc gggctcttga gtaataacca
    42061 aggccctccc atgcttttaa aagcttttct tctggagcat ttgctagctc ttcaattgta
    42121 ggaaaccatt ccatgaaacg ataaaaataa tcgatcactg tgtctactct ggtttgctga
    42181 agcatgatct cagagatcca gatacgataa ggatcacgat tatagcgcca aggcaggttt
    42241 cttttttctt gttcatacca ttgaatgaac tgatcttgaa attcttttgt ttctttatct
    42301 gtccattttt cccattcttt attcactttc ctcttccttt tccgtaatga atcgctggat
    42361 catatccaaa tcaaatcctt tttgatataa gctttgcttt acttttagat ttcttttttt
    42421 aggttcaaac cttaaatttc ttcgccatag tttatctcct tgtttgacta aataatcata
    42481 ttctatttct tgatctgctt cttgcggaag atcagccatc gcttgttgga tcacttcttg
    42541 agaaaaacct ttcgtcatca atgtttgttg gatttttctc aataattctt tttggctttt
    42601 tccgcgattt tttccaaacg ctttttcggc tgtctgatgt gcattttgaa cttggtcttc
    42661 aaatgtatat tggctgagcg cttgttcaat gatttcaggt ttcaaacctt tttgctgcat
    42721 ctgctgcgct aatttctttg gtcctttgtc acttaagcgc atattcgtgc gcacataact
    42781 ttccccatag accaaatcat cgacaaggtc caattctttt aagcgggcta cgattttatt
    42841 tcgatcttct tgaaggattt ccttttcttt taagtatgtt cggatttctt tttccgatcg
    42901 caactgataa cttaagtaat tcattgctag gtgaaaaccg aaatcagctc cgctactctt
    42961 cttgatctct tggatagttt cttcgtctaa ttcccgtcct tttaataatc gatagcgtac
    43021 taatacatct tcagatactt gtaaagcttc tccttcagat aaatctacgc gatagaaagg
    43081 gcctttgcct ttactgattc tcgtaacggt taacataaac atcctcctcg aacatatatt
    43141 ctctatcata ccacagaaaa tccccgtaat caggtattat atgttagaat aaaccacaga
    43201 aaaaagaaaa agggagatac ttatggcaga aacaattgtc aaaactggac aaacggttcc
    43261 tttgaaaatc aagcgtttag gcataaatgg tgaaggaatc ggttatttca aacggttgat
    43321 catatttgtt ccatatgcac taccaaaaga agaagtacta gtgaaaatca cgaaagcaac
    43381 tcctcgctat gcagaaggag aattaataaa agtcaaaaaa acaagcaaag atcgcgtagt
    43441 ggcaccatgt cctgtttact atgaatgcgg tggctgtcaa ttacaacact tagcttatca
    43501 agctcaattg gattttaaaa aggatctgct tttgcaagca ttggaaaaat tcaaaccagc
    43561 aggctttcga tcttatcaac ttttgccgac gatcgggatg gatgagcctt ggcattatag
    43621 aaacaaagca caatttcagt tacgaaaaaa taagcagact caaaaaattg aagctggttt
    43681 atacgaagca aactctcatc agttagtccc tataacagac tgcttggttc aagaacctcg
    43741 aacacaaaaa gtaatgaata ctgttgttca actattgaat aaatttgatg cacccatcta
    43801 tgatgaacgg acaaacagtg gaatcttccg cacaatcatg gttagaatcg gtgttaaaac
    43861 tggggagtta caagttgttt ttattactcg cagtaaaaaa ttcccgcaaa aaaacgcaat
    43921 gatctgtgag atcaatgaac gactgcccga agttgtttca atcatgcaaa atgtccaggc
    43981 acaaaaaacg tctctcgtga tgggggatga aacgatccac ttatggggaa aagaagccat
    44041 tgaagaacaa atcaatgaag tgactttcga tctttctcct cgtgccttct ttcaactcaa
    44101 tcctcagcag accgaattgc tttatggcga aggaatcaaa gcattagatg tccagcctaa
    44161 tgaaacgatc gtggatgctt attgcggagt tgggacgatc ggcttaagtg tagcaaaaca
    44221 agccaaagaa gtacggggaa tggataccgt tcctcaagca atcgctgatg caaaaaaaaa
    44281 tgcggaaaga ttaggatatc acaacactcg atatgaagtc gggacagcag agcaagttct
    44341 gcctaaatgg ttgaatgaag gttttcagcc tgatggtatc atcgtagatc caccacgtac
    44401 gggtttggat aacgcattga tccaatcatt attgaaatac cctccaaaaa aacttgttta
    44461 tatctcctgt aatgtttcta cacttgccag agatctggtt aatttaagta aaaagttcaa
    44521 gattgaatat ttacagtctg tcgacatgtt tcctcagact gcacgttgtg aagttgtcgt
    44581 gaagatgacg agactcgctg actaaatgaa agaggttgtg aaaaagtctg ccctgtatca
    44641 agtaataaga acagccaaac aaaaatagct cttcatgttt tatgaatacc gtacttgtga
    44701 ccgaagagtt aacaggagga cactatttat ttaaaaaaag ggttgtgaca tagtttttgt
    44761 cacagccctt tttgattatt attggatatt cacgtctatc acttgataaa atgcatttgt
    44821 cgtatcgctg atattccata ctgctaaaat cacattatat ccttttcgat cctgcggaag
    44881 tgtgatcgtt tggttgactg tttttggtgg aacagttgct ttgtcgtcta tttttgtgat
    44941 caattcaaaa tcactaaatt tcaaaggttg attaggattc caagttggtt tggtaatgta
    45001 gtaatcccaa gtacttgtcc gatgttgtgc tgttaaattc caagtaatat ttaatgttcc
    45061 tggattaacc atgtttttat gccatctgtt agatgtctgt tcatctaaag gctcaaagcc
    45121 gctgactcct gcactagcaa tttttccatc aatgaatgta tttttggtag cttcgatact
    45181 ttgcggttcc cattgtgctc ttccgacatt ttgatttaag tttcctgctg ctgatgttcc
    45241 taggtatgca cggcttcctg gagaagtaat ataaccatgc gcaaaacctg gaatgctaaa
    45301 accgaacaac cctaaactaa ctaacccaat aaacaataac gtactaatct ttttcatgta
    45361 gaaacctcct tcatttgata accacattgt aaacgcttta ttgtattaac acaaacatta
    45421 tgcttttata attttatgtt gaagtaaaaa aggtgaaaaa agtaagatgc agattataac
    45481 agaagtagac gagaaaagta caaatagaaa acatgagaac caaatcatat gatctttttc
    45541 aaaaacatca ttcatataaa caaatgttca actttttaat aacaacaatc atcaattttt
    45601 ttcttacttc acaaactaaa tacaggtctt gctgtgagcc ttcatggtaa actactatta
    45661 tagaaaggag ttagtaaaat gaagatgata aaagatattc gtttttgggt ttgtgttata
    45721 ggaattgtca tattaggctt tttatcaggg ttgcttagcg gaaatcccgg agaatattac
    45781 tattctttgc aacttccacc atttgcacca cctagctgga tatttgggcc gatgtggacc
    45841 ttactgtata tattgatggg tatttctctt tatttgttac ttaatcacaa caacaaaaaa
    45901 cagcgaaaca atcttgtcgg tctttttgtg attcagttca tttttaattt tatatggtct
    45961 gctctatttt ttaatttaag aaatattttc attgcagcaa tcgatattac acttttagtt
    46021 attttcttgt cagtgcttat gtatcagttg tggctacatc atcgcctggc aatgtggctc
    46081 atgattcctt attatttatg ggtactattc gcaactctat tgaattattc aatttatttt
    46141 ttaaactaag cgctaaaaag agacgtcctg taatttaaca catagaaaaa gtgccaccta
    46201 agttagattt tttgtctaat ttaggtggca ctctttatta accaaactat ttttttctag
    46261 tacccacttg ttgttccata ctcattattc tggtcataac cataaccatt ttgttcctgt
    46321 ccagcgtaag gatcataact ttgagtatct tgacttggtg tatagtactg acttgtatct
    46381 tctgtttgct gataataggt attcggatct tggtactgat catatgtgtt ttctgaatag
    46441 gaagaataat cggtgtaccc ttcactattc gatccatcac cgtttgtcga atcgccatct
    46501 tccgaatcat caaagaacat cattgaagca ttctcatttt tcaaattagg taatgtatcg
    46561 cttgttttta tatttaattg tttcttcagt tcattttgga tcgaaagaag atcatttttt
    46621 cctaaaattt gatagtagat atcattgatc atttgtcctt cgccttgcaa ctggtcttgt
    46681 ttgattgttt caaacgcagg ggtgtagttc gtcgctacat caagcatgtc atcccaatct
    46741 aagtccgtcg tcacattgtt ctcaactgct tttaaaattt ttctataatt gcttacgcca
    46801 tctaaactta aaactttatt gacgattttc gtcactactt cccgctgacg acgttgtcga
    46861 ccgatatcgc cttctggatc ttcgtgtcgc attcgagaat aggctaaacc tttttctcca
    46921 ttcaatgttt gttcacctac tggtacatgg acaccatcca aagtaaagtc aattttatta
    46981 ttcactttga tgccaccgac cgcattgatc aaatcttcca tgccatccaa attgatcgtt
    47041 acataatgat caataggaat atcgagcagt tgctcaattg aatccatggc catttcgaca
    47101 ccaccaaatg cataggcatg atttaattta tctaccgttc cataacctac gatattcgta
    47161 taaatatctc ggtccaaact gatgatcgtt gatttttttt gtttcggatt aactgttact
    47221 accatcatcg tatcagaacg tccttgttcc gttcttccta atccaccggt atctaaacct
    47281 aatagcaaaa ccgaaaaagg ttctttgtca tcaatgctta ctctctcaga acgtttggag
    47341 gatattcgat tagagttttt agaaattttg tttactgttt ggctcgcttc tcccataaat
    47401 ctgattccgt atgctgataa tccggcaatc agcaaaacaa atacccctaa caaggttaat
    47461 agaacttttt gccatcgctt cataatacac ctctgtttca cattttctaa aatattgtct
    47521 catataactg ttcaatcagc aaattcactt tttaatcata agaaaacttt aaaaaacatt
    47581 tttgtgtaac gattactatt ttttaaaatt tctcaaaatt cttaactatc ataccatacc
    47641 gtgaaaaaga tcgaaagacc gaatacacgc agttcgcaat cgttttatct ttttttacgt
    47701 attttttcca gaaaaagcga acaacaaggt attttccaaa taatcgtgca gtaaaatgat
    47761 cgcacatacc tttcccatct ttttaacagt ctttgcctac cgttcagatt atcattcgat
    47821 ttcacgaaaa tttcttccta tgactggtcc ttttgttaaa cccatcttct attcgtttta
    47881 tttccagctc actgcatggc tcttaaaatg actcgaacta gtgatttcat taccatcatc
    47941 ttttaatgga tagatatgct cctcttcaaa gtaaaacgat tttcttttaa agtaatagaa
    48001 ttgacatggt aatgagtatg tatactagtg gtttcacaaa tggtctttta ttcaacatcc
    48061 aaaaactgaa atttctttaa aatccattac taacgaagaa aatgttcctt gcttgataat
    48121 tagttaggac atgtcaagtg aacaaatgca tttacttagc caaaaaatct aaaaacttca
    48181 taaatagaca aaaagacacg actctctaag aagtcgtgtc tttattcaac aaattattat
    48241 aatttagtca cttcagcagc ttgaggtccg cgtgcacctt caacaatcgt gaattctact
    48301 tcttgacctt cttctaggct cttgaagccg tctccttgaa ttgctgagaa atgaacaaat
    48361 acgtcatctc cgccgtctac tgtaataaac ccaaatcctt tttcattgtt gaaccattta
    48421 accgttccgt gttccataaa tgtatagcct ccaaaaaagt tcttgcaagt aaccttgcaa
    48481 gaacattata cccaatttag aaaacgctag caagctttcg ctcttttatt ttccaaatta
    48541 tttttaagac tgatatgacg gaggaaatgg ttattttgct gcttcgaaac gtttgtttac
    48601 ttcatcccaa ttaataacat tccagaatgc tgcaatataa tctggtcgga catttttata
    48661 tttcaaataa taagcatgtt cccaaacgtc caaacctaga attggtgtct ttccttccat
    48721 caatggagaa tcttgatttg cagtagaggt aatagctaat tttccatttt ccattacaag
    48781 ccaagcccat ccagaaccaa atcgtccagc ggctgctttt ttgaattctt ctttaaaaga
    48841 agaaaaatca ccaaaagctt cattaatcgc ttcttttatt tctcctgtag gttcgccacc
    48901 agcatttggt gccatgattt cccagaaaaa tgaatggtta gcatgtccgc caccattgtt
    48961 acgtacagct gtcttgatat ctgttggaat agcgtccata tcagataata attcttctat
    49021 tgttttttcg cctaattctg ggtatttctc aattgctgca tttaaattcg tcacataagt
    49081 attgtgatgc ttatcatgat gcagatgcat cgtttcttcg tcaatataag gttccaatgc
    49141 gtcatatgca taaggtagat ctggtaatgt gtaagtcata aaaaaattcc tcctcaatgt
    49201 tttctttata atgtctacat tacaaagagt aacaaagaga aggaaattct tcaattgtta
    49261 tgcctagtcg tctttttcac tttgacctac ttcttcttca aaaacctcag tttctttaaa
    49321 aataaacaac ttgctgaaaa tatagttcgc taggataaca ataatttgag tgatgatttt
    49381 cgccacatac tcattgctgt tcataacatt gatcaacaat accattgccc ccatgtccaa
    49441 tccgtaagaa aggatacggt agaagaagaa cttaccgcat tcaataagtg catgtgtaaa
    49501 attcggtgat tttgaatgga atacccaaag tttgttcgtt acaaaagcaa acaatacaga
    49561 acaaaaccac gaaatagaat tggataaggc catacttaaa tcaaaatatt ggcgtgcgag
    49621 agcaaaacta acaaaattta caatcgtagc caaaccacca aaaaagagat agactagtat
    49681 ctcccaatat ccttttgctt ctaaatatcc ttttaactgt cgatactgct tcatgagcca
    49741 acctacctta ttaaaaattc ttatttatca tactctatat ttcaataact ttcatcttta
    49801 tttaaaaaaa ttaatttttt ttgatccttt gcctttgtct ctgcttggat cgtcacatgt
    49861 gtaataccat attttaattt taataaagaa attatacgag gatatatctt ttcaatctcg
    49921 cttagtagct gatcttcaaa atcaatatgt ccgtcgaaaa taattatctt ttcgctatac
    49981 tgccaaatat ggacatgatg aacattcttt accccatcga ttgcttcaat ttcttgttcc
    50041 attttttcat agtcaatagc aggtgcactt tgtatcaaaa tagcggcagc ttttttgatc
    50101 accattatcg cttctatcaa tatatatatc gaaatgatca gtgtaataac tggatcgatc
    50161 cagtagatat cgaaaaaacg gatcaaaatt gctccgataa tcacacttac cgaagacagt
    50221 gtatcactta acaaatgcaa ataactagat tttatattca aactttcatc tgcttcttgt
    50281 cgtaataata atactgagaa caaattcgcg agcaatccaa taactgctac tgttagcatc
    50341 aaatgactat ttatcttttc tggtgaagtg aaccgcttga atgcttcaac ggttaaaaac
    50401 aaggataata tgatcaatat gaatgagttg atgaaagcac tcaatatttc taaacgctgg
    50461 tagccatacg tacgtttttt atttgcttct tttcgggcca ttttttgtgc cccgtaagaa
    50521 aaaataattg ccaatgtatc actaaggtta tggaaagcat ctgaaacaag agacaaactc
    50581 cctgacataa tccctccaat aaattctgat aaagtgatca ccgcattcaa aaccactact
    50641 ccaaatagtt tttttgatga tctctgtggc tgtgtaggca ctattccttc ctccatttta
    50701 tttatattgg atagtcttta gacaagaata acattttttt gatatttcac caatcattca
    50761 gatgtttccc taaagcactt gtatttcact tgatacttcg ctagaattgc aagtgatgac
    50821 actactagat gaggagtact tatgacaaca aaacaattaa ttatcagttc ctttatacga
    50881 ttcaaagacc taaaggaggc gagaaatgtc ccattttgga aagccattgt ctatctttta
    50941 gttttgagta taattatggc tttgccaatc tcttttcaag tttttcaagt cttaaataac
    51001 attcaattgg atgggcaaaa gattgctact cgcattcctg attttacaat ccaaaacggg
    51061 cagcttcaaa ccgaagaaaa agaaggattc atttaccaaa caaactccat tatcttcaca
    51121 tttgatccag agggaaaacg aacagaacag gacatctcta ctgatttgat ggggaatttt
    51181 gttagtgtcg ggatgttaaa aaacaaactt atcatagctc ttcctaatac aggcacgact
    51241 tctgctttgt tgaacaataa ccaattagaa cttccctaca ccaatgaatc tttaaaaaac
    51301 ttaacaggta agcagctccg ttctttttta agtgaagcat ctataccact ttggataaaa
    51361 gtcctgacat ttatattttc tatttatcct agttttctga atctgctgat cactttgcta
    51421 tttaccaaca ttgctgcttt tctctatgca cgctttcgac taacaaaagc tacttttctt
    51481 gattgtttaa aaacattgat ctattcaatt tcattgccta ctataattgc aacaatcttg
    51541 atggtctttc ttccttcttt tgacactagc gccttcattg cttttgcagg aatctttatt
    51601 tttgctcaag ctgtcaaagg atgggcaaaa atatcgatca attaagaaat aaagacaact
    51661 cgttatttct acttaaatag acccttttag aggttgtgac atttttttgt cacagcccct
    51721 tttttatttg aaaaatattt ctttctcaaa aaacaagcaa ggcgcttcaa agttcttctt
    51781 gtatgcgcta cacttagagt aaagaaaggc gggaaattaa ctatgtcaga aagaatcatt
    51841 tatgcagatc gtccatttcg tgatgaattt atcgaagaaa tccatactat agcgcctggt
    51901 tatatcttta aaacagaatt acaaccagag gatctacaaa atgtagagat cagtttgggc
    51961 tggaactcag actaccaaga aaaactatta gcctcttcta ccttgaaatg ggtccaatct
    52021 atctcagctg gtgttgatca gctacccctt gagacttttt caaagaaaca tattttactt
    52081 tcaaatggta gtggcatcca cagtgaatcg attacggagc atgtcttagg aatcatcctt
    52141 gggtattctc gtggtctttt tcaagcacaa aaggcacaga gtgacatgaa atggttaggt
    52201 tcatcggtcc attaccaatc tatccaaggg aaaaaaatac taatcattgg aactggccat
    52261 attggaaaaa tgattgcaaa aaaatgcaaa gcattagaca tgaactgcta tggaatcaat
    52321 acatccggtc atccagcaga aggaatggaa aagacttttt ctttaaatca actaaaggaa
    52381 gttcttcctg aagtagattt cgtagtcaat atcttacctc taacggagga aacaactggg
    52441 ctctttgatc agcatatgtt tgaacacttt gatccaaaat ctgtattcat caatgttggc
    52501 cgtggtgctt ctgttaagac acaagatctg gtgcaggctt taaataacca gcaactttcc
    52561 tttgcagcat tagacgtttt tgaggaagag cctcttccac aagatcatcc tctttggaaa
    52621 atggacaatg tactgattac ttcccacatt gcaggtttga cacctgattt tcaaaagaaa
    52681 ttaatggcta tttttttaac caatctgaaa agctactttg ccacccatga gcttcaaacc
    52741 aatcaagtaa aattgtctgc aggatattaa tagctgaaaa caatattttc aaaagaaaaa
    52801 agagaaggtg acaaaaattg tgtcaccctc tcttttttta ttgtttttta aagtgatagg
    52861 ttggctcctc caggttggga tcataatcaa caagtaaatc atatccttta aagaaccatt
    52921 catctgcttc ctcgataaaa aaaagtgtcc catccatttc cactttcttt acaggatgtt
    52981 ctggctgttc aactgacatt ccaatcgaaa aaccatcatg aacctctgtt ttgccgtaga
    53041 cttttccaaa aaaacgtatt ccgtaagttt ctggcagatc aatttctgag tcaaaccatt
    53101 tttgtgcttt tggcgttacc gttaatttca tcccaacaac ctactttctc ttttctttct
    53161 attgattcat cttatcgtct agaatatcca catcgcctgt ctctccaata accagtagat
    53221 tatcattttc acgaacatat tcatctgctg caggagaagc gataaccgtt tgatctactc
    53281 ttcgtatggc gactactgtt aagtcaaaac gttgcctgaa atttaattca gctaatgttt
    53341 tgttgaaaaa tttaggattg gagactcgga tttctgctaa agaatattta tctgacagct
    53401 ctaagtagtc tagaatattc tttgatacta agttatgtgc aatccgtatc cccatgtctc
    53461 gctcagggtg tacgacacga tctgctccga tcttctctag tacacgggca tggtactcat
    53521 tttgggcttt tgctaaaata ttcggtacgc ccatttcctt taccatcaga gtaactaaga
    53581 tgctggcttg gatatcttct ccaatagcga caattacatg atcgaaattt cttataccta
    53641 atgaacgaag tgtcatctca tcctgtgcat ttgccacaac agcatgggtg gctatattca
    53701 tatattcatt gactcgatct tcattactgt caatagccag tacttcttgt ccagcttcga
    53761 tcagtgtacg gcagatgctt ccgccaaatc gtccaaggcc tacaattgca aaattttgtt
    53821 tcaccatttt cctcctttag tatcttcttt tctcagtata acaaagcctt tccaaaaaca
    53881 aaagcaagca tcattattgt aaaaaagcca agaaaaataa tagttatttt ctcagctttt
    53941 gattatcctc tttatcatcg tttttatttc accaaaccat gtttaaacgc atagatagct
    54001 gcttgagttc ggtcttctac ctctaactta gctaatatat tcgacacatg cgttttgact
    54061 gttttcagtg tgataaacaa ttcatccgcg atttcctgat tacttttccc ttcagaaatc
    54121 agcatcaaaa tttcattttc tcgattcgtt aattcttcat gcaatactgg atcatttcgc
    54181 cgactcattt tttccatcat ttttgttgtc acttcaggtt ctagtactcg ctcgccgcgt
    54241 tgcgtagccc ttatagcatc agctatttca tgtgctgtag acgtcttcaa caaatatcct
    54301 gctgctcctg cttcaattgc aggataaact ttttcatcat caataaaact tgtgacgata
    54361 atgattttgg cttttggcca atcttttaag attgcttttg ttgattcgat gccatccatt
    54421 tcttccatga ctagatccat taaaatgaca tccggtcgaa gtgccatcgc cttttcatag
    54481 ccttgacgtc cattttcagc ttctccaatc acttcaatgt cttcttggat agataaataa
    54541 gaagagacgc ctaagcgtac catttcatgg tcatctacta ataaaacttt tatcatcttt
    54601 atctatgcct ccttcatcaa agggaccttg gtctccacgc tcgtaccttg ccctttaaaa
    54661 ctaatgattt ttactgttcc accaatacca gctactcgtt ctttgatatt gttcaatcca
    54721 taacttcccg ttttggtttc attcatatta aatcctgtcc cgtcgtcaat gatacgtaat
    54781 aaaagattgt tatctatttt atgcaaatag acttctaatt cattagcctt agcatgtctt
    54841 aatgtgtttg ataacaattc ttgaacgatt cggaacaagt gatcctcaat ggaactagtt
    54901 aattttacat cttctacctc ccattttagc gaaatctgga ttttattctg caattccttc
    54961 aataactgct caatgccttg ttttaaactt ttttcttcta aattgactgg acgcagatga
    55021 agaagcagcg cacgcatctc agactgggaa gcgttgatga tctctgccac cattttcaac
    55081 tgcttacgga acatttctgg tgtctcactt ttttctgctt gctccgtcaa tgccgacatc
    55141 atcatcatcg ctgcaaataa ttgctgtgaa actgaatcat gaagctcacg agctaatcga
    55201 tgcctttcta attttaaaat ctcttctttg gtttgtccat ctacatattg aggacggcta
    55261 gtcataatct gtaattcact ggatacttcg atcatttttt cttttatttt agtaatttcc
    55321 atatcaatat ctttgatgta cagatcatcc gacgcgcttg ggatcggctg atgcaaaagt
    55381 ttggattcat aattgccaga agaaagtgca cgaagctttt cttcgatttt cccgtatttt
    55441 gccttttgaa taagtgataa caatagaaat acgatcaatc ctacacctaa tgaaattgcc
    55501 atcaaatgga agataagcgg aacgtataat aaacgcgcac gcagcaattc tccccaccaa
    55561 tgactttggt tactggcata aaaataagtg aaaagtgaaa atagaataat aaggaaagcc
    55621 gcaatccccg aataaacagc tagcattgct ttggatattc ttcccatcat attcgtatca
    55681 cctcgacatc tccaaccaaa gtattggtaa tgatcttcaa tctgcgagga ttttcatcat
    55741 aatcactgct gcagattttg atctgttcgt tttttaagga aaactgctct tcttcaaaca
    55801 agacatttcc tactaatgtc gcatgctcta aacgaatagc cactcccagg ggtactaaga
    55861 tccgtgttct gcctatccct tttcttacaa tcacaatatt atcatctttt ggcaaaagtg
    55921 tattgcccaa atcgatgata gtatcaccag aaatgatggc aatgttgata tcatcccatt
    55981 catagacgtc gtttccaata cgttggttac caaataattg ctgtctttta cgctcattat
    56041 tatgtgtttt taattgctct gtttggacca tcatgatctg tttttttcgc caaaaagcat
    56101 tttttgtcaa atctattcct gaaatctcta cacctttcag cccgataaat aaaacggcca
    56161 atacaaccat catccataaa gcaggactgt tgactaagct aaaaaaaatg accaagctcc
    56221 ctaagatcaa ttgaaaattt tgaaatttag tacgaggata tttgcgcata gctagatata
    56281 tattgaaaat accgaatatt actaaaagca aaagtccagt attgtttacg atttgccaaa
    56341 cagcaaataa cagcagcagt gcttcgacta ccacaaaaaa acgccaagaa ctattcatcg
    56401 ctttttctcc ctcctgacac attctcattt catcatacct atttttttga ctgttggcta
    56461 taggacttta gatgtaagat cgttcagtga aacctgcaat actcaaagag aaaagatcta
    56521 gagtgcgtca tcagtaagat gaactctcta gatctttcag tcagactacg cttgttctac
    56581 tttgacgatt ttaactaaca tatcgccacc tggtgtagca atggttactt catcattttt
    56641 acgtttgcca atcaatgctt gcgcgatagg agaatcattg gaaatctttc cagaaaacgg
    56701 gtctgcttca gcacttccga caatcgtgta ctcttcttca tctccatcag gcaactcgat
    56761 gaacgtaact gttttaccga tcgatacctc atctgcatct acgccgtcat tatcgatgat
    56821 ttgtgcaaaa cggatcatat tttcaattgt tgtgattctt ccttcaacaa atgcttgttc
    56881 atctttagct gattcgtatt cggagttttc ggaaagatct ccgaaaccgc gagcgatttt
    56941 gattcgttca atgatttctc cgcgtttaac tgtttttagt tcttctaatt ctttttctaa
    57001 tttttcttta ccttctagag tcattggata aactttctct accatgtgta acgtctcctt
    57061 ttttcgataa aataccgcaa aaggtaatct tttgaggaat atagtccaaa aaagattacc
    57121 acgcttttct taaaatgtaa atgtttttct aaaaatgatc aatgactagc ccctgttttt
    57181 ctaagaatta tttacatatt tttgcactag ttccatatgt tcttcatacg ttttagcgaa
    57241 ataaacattt ccagtgctcg tatctgctac gaaataataa tagtcatttt ctgctggttc
    57301 taatactgcc ttgattgcct cttcgcttgg attgtcaaaa ggaccaggcc catagccggt
    57361 attggtatac aaattgtatg gtgaatctac agctgtatct tcatacgtca ccaattcttt
    57421 atgttctcct aatgcatata aaacagagat atctgactga agtggcatat ttgccttgat
    57481 tcggttaaag aagacttgtg caatattttt acgatcattt tcttttacgc cttctttttc
    57541 aactagagaa gccaaagtta aaacttcttg tacagtcaaa tttttctgtt tgatagctga
    57601 ataatagttt tgcatgaccg tatttgtttt gttcaccatc tcaatcacaa gatccttaag
    57661 cgaagtactc gtgtagtaat cataagtagc tgggaataag tagccttcca aacggtattt
    57721 tgtgttctca gctttagagg cactttccaa caattctggg aatttttgat acaactcgtt
    57781 aaagaaagtc tcatcattta ctaaatctaa aaattctttc ttgtctttac cagttacctt
    57841 cgctacccgc tcagcaatct gatcgatgtc gtagccttct ggaatggcaa ttttcccatc
    57901 tgcaactttt gttggctcag aagtgccgcc ttcttgcagc tgtttgccaa tctcgtcaag
    57961 agtcatatta ggcgctaact gataatagcc agcttgaaag ccagttaaat ttttaaattt
    58021 tgtataataa ttgaaaacaa tcccgctttt aataatattg tccttctcca aaatctcacc
    58081 aatctgcttg ttagaagagc cactcgggat ctccacttgg actaattggt catctgattt
    58141 atctaaaggc ttcaacccgc tatctacata acgatacacg gtaaatccaa gaaatccgcc
    58201 aataattaat aatgtaagag caatcactaa aatgatcttc ctcacaatct tatcttcttt
    58261 tttacgcaga tttctccgct tgtcgattat atctgctgta gctgccttac tggcttcttt
    58321 tttatcttta cttgggtgtt gtttgtttcc tgacaaaaca actcctcctt actatcatct
    58381 tcgtaactct gtttattata catgaaattt ctactgccgt gaattatttt accaaatatt
    58441 atgtcaaaat tgtaagtggc aaatactctt tttgaggatt acaatgaaaa atagttaaaa
    58501 atggatagaa aggaattaac atgtcaaaag gaaaacatcg aaaaaaacaa aaaatttcta
    58561 tttcttttct tgtaatttta ttattgtctg tcagcttctt ttcaacaggc atcattatag
    58621 gaggtcaatt aacaaaaata cctcattccc aaacttataa agcggagcca acacaactta
    58681 cttccaattt aacgcccgat gagcagaggc ttgctagcaa aattgatcaa ttactacaaa
    58741 aatcagatta tatcggttcg atttatgttc gcaaaaataa tcgcgtacta ttagaaaaag
    58801 gatatggata tgcaaatctg cgcgtaaaag aatcgaattc accttctatt tactatcaaa
    58861 tcggttcgat tcaaaaagca atgactgctt tactgatact aaaacaaatc caagctggta
    58921 agttaacttt tgacacaaag ttagcagaat tttatcctca gattcctgga agtcagcaaa
    58981 tcacaatcaa aaatatgctt tatatgcgct ctggtcttca tcgaactgct tctcccgaca
    59041 aacctatgtc ggatagtgaa atcattcagt tcgcccttca tcatttgaaa cttactgatt
    59101 atgatacgta tcattatgaa ccattgaatt atacattgct tacagggata ttgatcaaac
    59161 taacgaatca gccttatgaa actcttctaa aaaaagaaat cattcgtcca ctccatctag
    59221 aacatacaga tttttatgac aatgtaaaaa attcgcctca acatgctgta tcttaccaga
    59281 tgtctgcaac tgacgattat tcaaaagcat tgatcgagcc tgaaaccgac atccgaaatg
    59341 aattaggtac aggaaacata agtatgtctg tttatgactt gaacaaattc tttaccagtg
    59401 ttctttctgg cggtatcata ccaaaagaac tacttttctc attgtggcaa aataatggtg
    59461 ataaacatcc ttacagcggc ggtgtttaca gtggaaacga ttatatcctt gctcagggga
    59521 atatcaatcg attccatgca gtagtggcga tgaaaaaaga cactaaagat gcaatcgtca
    59581 tggaaagtaa tatccaatcg gataagaaca tcaaattgcc ggccactgat ttaagaaatc
    59641 agatttatga actgatggaa ggtgttcact tatcaaatta aattttgaca taatattagt
    59701 tgtcatctct gtatagtcaa tttagttagt actctatctg aaaagtagaa ataaattaac
    59761 aaatattatc tgtccttatt atttgttaat ttatttctta tttta
//
LOCUS       DAFKHN010000005        59090 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFKHN010000005 DAFKHN010000000
VERSION     DAFKHN010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.005"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            86..1387
                     /gene="murA"
                     /locus_tag="LY912_000323"
     CDS             86..1387
                     /gene="murA"
                     /locus_tag="LY912_000323"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBM6954048.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1400..1576
                     /locus_tag="LY912_000324"
     CDS             1400..1576
                     /locus_tag="LY912_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBM6954049.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            1711..2007
                     /gene="yidD"
                     /locus_tag="LY912_000325"
     CDS             1711..2007
                     /gene="yidD"
                     /locus_tag="LY912_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBM6954050.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2192..2659
                     /locus_tag="LY912_000326"
     CDS             2192..2659
                     /locus_tag="LY912_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6954051.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            2744..3628
                     /locus_tag="LY912_000327"
     CDS             2744..3628
                     /locus_tag="LY912_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBM6954052.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            3742..3978
                     /locus_tag="LY912_000328"
     CDS             3742..3978
                     /locus_tag="LY912_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBM6954053.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4066..4146
                     /locus_tag="LY912_000329"
     tRNA            4066..4146
                     /locus_tag="LY912_000329"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4100..4102,aa:Tyr,seq:gta)
     gene            4153..4224
                     /locus_tag="LY912_000330"
     tRNA            4153..4224
                     /locus_tag="LY912_000330"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4185..4187,aa:Gln,seq:ttg)
     gene            4349..4519
                     /locus_tag="LY912_000331"
     CDS             4349..4519
                     /locus_tag="LY912_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954054.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            4739..5446
                     /locus_tag="LY912_000332"
     CDS             4739..5446
                     /locus_tag="LY912_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6954055.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5505..6149)
                     /locus_tag="LY912_000333"
     CDS             complement(5505..6149)
                     /locus_tag="LY912_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBM6954056.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6275..6562
                     /locus_tag="LY912_000334"
     CDS             6275..6562
                     /locus_tag="LY912_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954057.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6670..6990
                     /locus_tag="LY912_000335"
     CDS             6670..6990
                     /locus_tag="LY912_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6954058.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7071..8384
                     /locus_tag="LY912_000336"
     CDS             7071..8384
                     /locus_tag="LY912_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBM6954059.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8381..9100
                     /locus_tag="LY912_000337"
     CDS             8381..9100
                     /locus_tag="LY912_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBM6954060.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9228..9779
                     /gene="raiA"
                     /locus_tag="LY912_000338"
     CDS             9228..9779
                     /gene="raiA"
                     /locus_tag="LY912_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBM6954061.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10001..12535
                     /gene="secA"
                     /locus_tag="LY912_000339"
     CDS             10001..12535
                     /gene="secA"
                     /locus_tag="LY912_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBM6954062.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            12661..13762
                     /gene="prfB"
                     /locus_tag="LY912_000340"
     CDS             join(12661..12732,12734..13762)
                     /gene="prfB"
                     /locus_tag="LY912_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBM6954063.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            13867..14553
                     /gene="ftsE"
                     /locus_tag="LY912_000341"
     CDS             13867..14553
                     /gene="ftsE"
                     /locus_tag="LY912_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBM6954064.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14537..15430
                     /locus_tag="LY912_000342"
     CDS             14537..15430
                     /locus_tag="LY912_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954065.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15582..17030
                     /gene="cls"
                     /locus_tag="LY912_000343"
     CDS             15582..17030
                     /gene="cls"
                     /locus_tag="LY912_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBM6954066.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17367..18224
                     /locus_tag="LY912_000344"
     CDS             17367..18224
                     /locus_tag="LY912_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBM6954067.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18339..19259
                     /gene="pstC"
                     /locus_tag="LY912_000345"
     CDS             18339..19259
                     /gene="pstC"
                     /locus_tag="LY912_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBM6954068.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTITTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19259..20143
                     /gene="pstA"
                     /locus_tag="LY912_000346"
     CDS             19259..20143
                     /gene="pstA"
                     /locus_tag="LY912_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBM6954069.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20158..20964
                     /gene="pstB"
                     /locus_tag="LY912_000347"
     CDS             20158..20964
                     /gene="pstB"
                     /locus_tag="LY912_000347"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBM6954070.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            20980..21738
                     /locus_tag="LY912_000348"
     CDS             20980..21738
                     /locus_tag="LY912_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBM6954071.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            21751..22428
                     /gene="phoU"
                     /locus_tag="LY912_000349"
     CDS             21751..22428
                     /gene="phoU"
                     /locus_tag="LY912_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBM6954072.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            22666..23697
                     /locus_tag="LY912_000350"
     CDS             22666..23697
                     /locus_tag="LY912_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBM6954073.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            23694..24461
                     /locus_tag="LY912_000351"
     CDS             23694..24461
                     /locus_tag="LY912_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBM6954074.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24561..26129
                     /gene="liaX"
                     /locus_tag="LY912_000352"
     CDS             24561..26129
                     /gene="liaX"
                     /locus_tag="LY912_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBM6954075.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26426..26746
                     /locus_tag="LY912_000353"
     CDS             26426..26746
                     /locus_tag="LY912_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBM6954076.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            26746..27096
                     /locus_tag="LY912_000354"
     CDS             26746..27096
                     /locus_tag="LY912_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBM6954077.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27263..28201
                     /locus_tag="LY912_000355"
     CDS             27263..28201
                     /locus_tag="LY912_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBM6954078.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANKNGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28216..29046
                     /locus_tag="LY912_000356"
     CDS             28216..29046
                     /locus_tag="LY912_000356"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBM6954079.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29090..30115
                     /locus_tag="LY912_000357"
     CDS             29090..30115
                     /locus_tag="LY912_000357"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBM6954080.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30130..31068
                     /gene="galU"
                     /locus_tag="LY912_000358"
     CDS             30130..31068
                     /gene="galU"
                     /locus_tag="LY912_000358"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBM6954081.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31193..31633
                     /locus_tag="LY912_000359"
     CDS             31193..31633
                     /locus_tag="LY912_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBM6954082.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            31636..32238
                     /locus_tag="LY912_000360"
     CDS             31636..32238
                     /locus_tag="LY912_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBM6954083.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32297..33403)
                     /locus_tag="LY912_000361"
     CDS             complement(32297..33403)
                     /locus_tag="LY912_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBM6954084.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            33613..34614
                     /gene="ccpA"
                     /locus_tag="LY912_000362"
     CDS             33613..34614
                     /gene="ccpA"
                     /locus_tag="LY912_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBM6954085.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(34951..37296)
                     /locus_tag="LY912_000363"
     CDS             complement(34951..37296)
                     /locus_tag="LY912_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBM6954086.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            37575..38477
                     /locus_tag="LY912_000364"
     CDS             37575..38477
                     /locus_tag="LY912_000364"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBM6954087.1"
                     /translation="MLLGSHVSMSGKKMLLGAAAEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            38690..40465
                     /locus_tag="LY912_000365"
     CDS             38690..40465
                     /locus_tag="LY912_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBM6954088.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(40531..42117)
                     /locus_tag="LY912_000366"
     CDS             complement(40531..42117)
                     /locus_tag="LY912_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBM6954089.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETVEEIE"
     gene            42368..42592
                     /locus_tag="LY912_000367"
     CDS             42368..42592
                     /locus_tag="LY912_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBM6954090.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            42733..44484
                     /locus_tag="LY912_000368"
     CDS             42733..44484
                     /locus_tag="LY912_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6954091.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTK
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIVMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPVKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            44484..46268
                     /locus_tag="LY912_000369"
     CDS             44484..46268
                     /locus_tag="LY912_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954092.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRTTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVLVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            46594..47445
                     /locus_tag="LY912_000370"
     CDS             46594..47445
                     /locus_tag="LY912_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBM6954093.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            47541..49421
                     /locus_tag="LY912_000371"
     CDS             47541..49421
                     /locus_tag="LY912_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBM6954094.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEAEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVSFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYIMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVRQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(49461..50363)
                     /locus_tag="LY912_000372"
     CDS             complement(49461..50363)
                     /locus_tag="LY912_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBM6954095.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            50594..51997
                     /locus_tag="LY912_000373"
     CDS             50594..51997
                     /locus_tag="LY912_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBM6954096.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            51997..53430
                     /locus_tag="LY912_000374"
     CDS             51997..53430
                     /locus_tag="LY912_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBM6954097.1"
                     /translation="MGFRKDFLWGGATAANQCEGAYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSNN"
     gene            53575..54501
                     /gene="trxB"
                     /locus_tag="LY912_000375"
     CDS             53575..54501
                     /gene="trxB"
                     /locus_tag="LY912_000375"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBM6954098.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            54715..56442
                     /locus_tag="LY912_000376"
     CDS             54715..56442
                     /locus_tag="LY912_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBM6954099.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            56457..56807
                     /locus_tag="LY912_000377"
     CDS             56457..56807
                     /locus_tag="LY912_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBM6954100.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(56899..57759)
                     /locus_tag="LY912_000378"
     CDS             complement(56899..57759)
                     /locus_tag="LY912_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBM6954101.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            57851..58279
                     /locus_tag="LY912_000379"
     CDS             57851..58279
                     /locus_tag="LY912_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBM6954102.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            58441..58617
                     /locus_tag="LY912_000380"
     CDS             58441..58617
                     /locus_tag="LY912_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBM6954103.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            58644..59090
                     /locus_tag="LY912_000381"
     CDS             58644..59090
                     /locus_tag="LY912_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBM6954104.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT        19232 a        10266 c        12732 g        16860 t
ORIGIN      
        1 aggtactatt ttaaaagcaa ggatgttata atagaaaaga ttttgagtaa gtgtatgctc
       61 attggaattt tttggaggga acaacatgga agagatcatc gtaagaggtg gcaatcaatt
      121 aaatggaaca gtaagaattg aaggagctaa aaatgctgtt ttgcctattt tagctgctag
      181 tttgttagca gaagaaggta ttacgacatt agacaacgtt ccgattcttt ctgatgtctt
      241 cactatgaat caagtgattc gtcacttaaa cgtagatgta gattttgatg aacaaaagaa
      301 tcaagtaaca atcgacgctt caagacaatt agaaatcgaa gcgccttatg agtatgttag
      361 tcaaatgcgt gcttcaatcg ttgtgatggg tccgctactt gccagaaatg gacatgcaaa
      421 agtagctatg cctggtggat gtgcgattgg taaacgacca atcgatttgc atttaaaagg
      481 atttcaagct ttaggagcaa aaattattca aaaaaacggc tatatcgaag caattgcgga
      541 tgaattgatc ggtaacacga tttatttaga tttccctagt gtaggtgcta ctcaaaatat
      601 catgatggct gccgtaaaag caaaaggaac aaccatcatt gaaaacgtag ctcgcgaacc
      661 agaaatcgtt gatttagcaa acattttgaa taaaatgggc gctcaagtct atggagctgg
      721 tactgaaaca atgcgtattg aaggcgtgga tcatttacat gcagtcaacc actcaatcgt
      781 acaagatcgt atcgaagcag gtacctttat ggttgctgct gcaatgacac aaggcaatgt
      841 gctgattgca gatgctatct ctgaacataa ccgcccattg atttctaaat tgatcgaaat
      901 gggtgcagaa atcattgaag aagaaggcgg agtccgtgtc atcggaccaa aacatatctt
      961 acctacagat gtaaaaacga tgcctcatcc tggtttccct acagatatgc aagctcaaat
     1021 gacagctatc caattagttg cagaaggtac aagtgtagtg actgaaacag tgtttgaaaa
     1081 tcgtttccaa catttagaag agatgcgccg tatgaacgct catgtcaaaa tcgacggaaa
     1141 tgtagcaatc atggatggaa accatgaatt gcaaggtgca gaagtatatg caacagactt
     1201 gcgggcagca gcagcattag ttttagctgg cttgaaagca aatggaatca cacgtgtgcg
     1261 taacttgaat tatctagacc gtggatatta taatttccat atcaaactac agcaattagg
     1321 tgcagacgtt gaacgtgtag acatggatca aacttctgct gaaaaaacag cacaaacgat
     1381 tgcttaagga agtggctgaa tgagtaacca acgatatatc ttattaactt tgataaagat
     1441 tttaatggtg atcttattgc ttatccttct ttttgtggcc ggaacgatga tcggatatgg
     1501 tgtcatcggt ggcggcaatc catttaaagt atttcagcca agtttgtgga ttcatattcg
     1561 agactttttt cattgataaa taagaatcac agtggttcta gtcgatatga agtgagccat
     1621 gaagcagaac atgataaaag aaaacagaag ggaacgttga cgttagtcgc gatccctttt
     1681 tttagtaaaa gaaaagaagg aatctaattg atgaagaaga tattgattta tttagttaga
     1741 ggatatcagc gctttatttc gcctgcattt ccacctagct gccgttatta cccaacctgt
     1801 tccaattata tgataaaagc aattcaaacc catggcgcgc taaaagggac ggtaatgggg
     1861 actgcacgga tcttacgctg tcatcctttt gtcaaaggcg gtatcgatta tgtaccattg
     1921 acattccgat taacgcgaaa taagaaagat aaaaaagaac cagattataa aaaggttgtg
     1981 aaaaatacgg gtagcactga gcgataaaga aacaatttgg aaaatagctt cttatatttt
     2041 gcaaaattgt gagttattgc cgaagtgttg gattttgaac accgtcaaaa aaaaggttgt
     2101 gaaaaatacg gctagcactg agcgataaag aaaaagagga aatttattgt caaagtaaca
     2161 actccgcaac tacttatatg ggggacaaaa aatgatcgaa gaactaaaca agaaagattt
     2221 accatggtcc ttgttattag atgcagatcc tgataaagaa aaagttcaag tatatgtttc
     2281 cagagggagt ggctggatat ggaaagaaaa agaaaaaaca ataggtgtac tgatctatgt
     2341 ggcaagggaa aaagaatacg aaatcgtcaa tgtagcagta accccaacgt atcaaggaaa
     2401 ggggattggc ggaaaattac ttgagacagc ttttcagaag ctttcacaac tcgcttccag
     2461 tcaaactcag atcatcatac gaaccggcag tactagcagt gcggcgttac atctctatca
     2521 aaaaatgggc tatgtggaga ttggtcgagt caaagactat tttatccatc attactctga
     2581 gcccattttt gaaaatggag atcaattaag ggatcaagtg attttagcaa ttcacttacc
     2641 taaaaatagc tttaactaat aaaatttcaa ttcaagaaaa tgctttcaaa tgctaaatag
     2701 atacattaca atagctttag caaacaaaaa ggagaatatt tttatgggaa tattagtttt
     2761 tgattttggt ggatcggctg tcaaatatgg ttgttgggat ggcaaagaga ttaaaggtaa
     2821 gggacaattt gcaacgcctg aatcttggga agaaatgaaa gcgcaattat ttcaagttta
     2881 taaaaaaata ctcgtttctt ttgaagtcga aggaattgga atcagctctc ctggagtagt
     2941 gaataatgag aaacaggtga ttgagggaat cagtgcgatt ccttatattc atggatttaa
     3001 tattttccga gatttggaaa ctctgtttca acttccagta acgattgaaa atgacgccaa
     3061 ctgtgccgga atggctgaat tttatgaagg tgctgcccgc gattatcaag atgttgcttt
     3121 tgttgtggca ggaactggga ttggcggggc gttgttcacg aaaggacaaa tcaataaagg
     3181 ggcacatctt tacggtggag aatttgggtt gatgttctta aatggcgata agacattcag
     3241 taaacttggt acagcggtac agatggcttg gcgttattgt gaacgcaaag gtctcgataa
     3301 aaatgcttat accggaaaag atgtctttga attagcagaa actggagatg caatagcaaa
     3361 agaagaagtt gagagttttt atacgtatct tacaaaggga ttattcagta ttcaattttc
     3421 gtttgatcca gaagtgatcg tattaggcgg cggggtttct gcaaaagaag ggctcattga
     3481 tgagatcaaa agccgaatga agaagctgac agaacaattc gatctgcatg atttcgaacc
     3541 gcagatttta ttatgtgaat acagaaacga tgctaatctt gtaggtgcag cagcaaacta
     3601 tctcgctgta cgtcaagggg agaattaaga gctttagaga aggtgcagct tgcataaaag
     3661 aagtgaatga aatgaatagg agatttttac ctaaggaatg ttttatttgc tgcagtatga
     3721 taaaatatct gagaggtgaa aatgatgtca aaaaaaaata aagatattga agtgcgtata
     3781 gaagaagtga aaaaagatat caaaggtaag aattatgaag tcactcagtt atttataggg
     3841 aaaaaaatga ttggtgagat cttagcctat ggaccaaaag aatatgaaat tttctttggt
     3901 gaagaagatt ttggaaaaga aaaaagtctt gaaaatgcga tagaaacagt gattcgacac
     3961 tggaatctgc acgaataaaa aaatatcaaa aaaactttca ataaagggtt gcaaaaatct
     4021 ggaaaattag gtattataac taagtcaggt tgatacaaac ctttcggagg agtagcgaag
     4081 tggctaaacg cgacggactg taaatccgtt ccttagggtt cagtggttcg aatccactct
     4141 cctccatttc attggggtat agccaagcgg taaggcaagg gactttgact ccctcatgcg
     4201 ttggttcgaa tccagctacc ccagtatacc acaatcgtaa gctctcgtta gttcgagagc
     4261 tctttttttt gctttgctac cttgttcctt gaagattctg ctgatttaag atagagttaa
     4321 gttaactaca agaattggag ggatccacat gaaatggaaa gaaaaagtag acgaagcagc
     4381 tgaaaagtta tatgatttgg tcaaatcaga aaaatacaat attgaagtga atattccgaa
     4441 aaaaggcgga aaagcggtcc gggtaaaatc aaaacgccca acgaatcata caaaaaaatg
     4501 gatggctaaa aaccgctaat aataacaaaa gatccataag tcggcatttt catcgatttt
     4561 agggtctttt gttattttct aggttggaca tatctaaaaa attgtttctg acaataggag
     4621 taggaagaac gatgtgtgtc taaatcctct gttgatggat agaaaccttt atctttttca
     4681 gttgtgaatc aggtatatac cagttataat agaagaaacg aaaggacggg tgtacgttat
     4741 gtcgaatcaa ttacctgtat atatacagat tcatgaccaa ttaaaaaatg aaatcgaaca
     4801 aggtatatgg aaagtcggag accgtcttcc ttcagaaaga gaattagcag tgaaattcaa
     4861 tgtcagccgt atgacgttga gacaagcaat tcaaaacttg gcagatgaag gaatcttaga
     4921 aagaaagatc ggttcgggta catatgttgc acgagaaaaa gtacaagaaa aaatgtctgg
     4981 tgcaacaagt tttacagaaa ttatggaatc acaaaatcga gtaccgtcta gtcggacaat
     5041 ctcttatttc ttgacttcgc caagctcaag tgaaatggaa aaactaaact tgagtaaaga
     5101 tgacacgatc ttgcgaatgg aacgtattcg tttcgcagat gatgtcccta tttgttttga
     5161 agttgccagt gtgccacaaa agctgatcga tggctacagc aaagcagaga ttactgaatc
     5221 gttgtatcgc acgctagaag aaaaaggcgg gaaaaagatc ggtccagcga atcaaacgat
     5281 tactgctgtg ttggcttctg agaaaattgc tgactattta gaggtaaaac gaggagatgc
     5341 agttcttcgt ttgcgccaga tttcttattt tgaagacggt acgccgtttg agtatgtgcg
     5401 tacgcaatac gtaggaaatc gttttgagtt ttatttggaa aaataaaaaa caggtgatcc
     5461 ctgattccgt attagaaata aaagagaatc agaatcacct gtttttatat atgatcagtt
     5521 accagttgct cgtgataaga aacaggaccc tcttcaaatt ggacttgtcc gttcagcagc
     5581 tcaatgatgg attctttaaa gtggtcagca cttttttcat ctacagcaca gatgacgcta
     5641 acttgatcag tatattggat ttcttttata aaaaaatgtt ggagttcaag ataattctgt
     5701 aattttccta gttgcggata cgtgatcatc acagagatct cctgttgcaa ggtaccttct
     5761 acgattccaa tgtcagacaa tgcttgagag accgcatgag tgtatgctcg tattaatccg
     5821 cctgtgccga gtttcgttcc tccaaaatat cgagtgacta ctgcagctac attgatcagt
     5881 tgattttttt tgaggacttc caacatcggt atgcccgccg ttccacttgg ttctccatca
     5941 tcgctgcttc gctggatttc atttttttct ccaatgatga aggcgctgca gttatggttc
     6001 gctttccaat gttctttttt tatttcttga atgaaacttt ttgcttcgtc ctctgattct
     6061 attcgtctaa gagaacagat aaagcgtgat tttttgatct cgatctcact ttgtccattt
     6121 tcttttattg tacgatagcg ctcgatcatc ttgtcacctc ttttttcatt ttctttattc
     6181 agtataaata aagttctagg ttgtttcaac actgtaacgg ttgcgcaatt gctgtagtat
     6241 gcgataataa agacaaaggc aggtggatct ggggatgcag gaacgaatga aaaagtacga
     6301 tgcaattacg cattatttga agaacaatgg cggctctcaa gtaacgttga cctttaccca
     6361 atttgacgaa ctgctgtttc ccagtaacgg acttcccaaa acagcaaggg aaagtacaga
     6421 ttggtgggca aatgattata aacaccctga aaaaggtgcc tatggctgga taaatgcagg
     6481 ctatgaagta gttgtcatca atttggacaa agaatatgtc gtgttcaata aattagtgaa
     6541 atctagttgg ctatttgatt aaataaaccg cgtttagaaa acgttgacaa atttctttct
     6601 ttttatataa tagagtaaca gacgcgaaga aaacgtttgc gtagtttgtt ttaaaaagga
     6661 gagaaaagta tggctaaaaa aacaatcatg cttgtatgtt cggctggtat gagcacaagt
     6721 ttactagtaa caaaaatgca aaaagctgct gaagcaaaag gaatcgactc tgatattttc
     6781 gctgtgtccg cttctgacgc agataacaat cttgcaaata aagacgtgga tgtgttgtta
     6841 ttaggcccac aagttcgctt tatgaaagct gattttgaga aacgtctgga accaaaaggc
     6901 attcctttag atgtcatcaa tatggctgat tatggtatga tgaatggcga aaaagtgtta
     6961 gatcaagcaa tcacgctcat aggtgaataa atagaacagt ataactatcg aacaagcgat
     7021 ccaaaaaata gatcgcttgt tttttcgtat atttttttag ggcgaataat atgaatcatt
     7081 tttggggtag aaggcttctg acgagagata ttaaagcaat agactgtgag gaggtaaatt
     7141 taccaaatta tgagaagatc gcagcagtgg aacgtttgag caactggatt ctttgtcatc
     7201 gctgtggaat gagaacgtcc gtcattgatg gacagcttgc agattacggt tatttttgta
     7261 cacattgtct atatttaggg cgatgcgaca ctcaacaaga tttatatttg tttgatcagc
     7321 ctgaagcaaa acctcgagaa gtcgtctttt tttggacagg acagcttact gaaaaacaaa
     7381 cggaaatctc aaagagaata ctttgccatt cagaaaaaag acatcatctt atttgggctg
     7441 taacaggtgc agggaaaaca gagatgcttt atcctatttt agtggaaact ttaaaagctg
     7501 gaggaagagt agcgatttgt acaccgcgag tcgatgtttg taatgaattg tttttacgct
     7561 atcgttatgt ttttccagaa gaaaaaatca cgttgctcca tgggaataca gcaacggctt
     7621 atacctttac ttcttttgtt atctgtacga ttcatcagct ataccgtttt tatcggtcct
     7681 ttgatttaat agtgatcgat gagatcgatg cgtttcctta taacggggat gcaggattag
     7741 ctcatgctgt gcaaacagcg attaaaccag acggacgatt catctactta agtgccacac
     7801 ctgataaaaa gttactaaag gagatcaagc agacgtttga catccacaaa cttgctttac
     7861 gctttcatcg gcgtttgctt cctgaacccg tcttggtttt catgaataat tggcgacaaa
     7921 aatgcaagaa caagaagaag ataaaatctt tggtgcggat cattcatcaa ttaattaaag
     7981 aaaaccatat ccttttattt tgtccaagta tcacgatgat gcatcgtttg aaagccacac
     8041 ttcaagaggc tcttccgaga tatgagatca cagatgtttc ttcaagagac aatcagcggg
     8101 cggaaaaagt ccagaaaatg cgagaagcaa aatatgacat actgttaacc acgatgatcc
     8161 ttgaacgtgg agtcacattt gaaagaatat ccgttatcgt tttaggagcg gatcatccgg
     8221 tttttactaa atcttctttg gtacaaatcg caggaagagc cgatcgtaaa gggccttata
     8281 cgaacagtca agtatatttt ttctatgaag aaaaaactgc agctattcga aaagcttgtc
     8341 aggaaatcaa agaaatgaat gaagaaggga agaagatact gtgaggtgca gttgctgcag
     8401 taaagatatc gtccaaaatt taacattcag cgagattatt ggtgtttcga aatacagatt
     8461 acctcagact tgttcagttt gtcgcgcaca atttcattta ttggaaacaa gaggctgttc
     8521 tggctgtcaa aaaccaatcc atttcaatct agagagtacg aaaaagaaag taaattctat
     8581 ccccgtttac tgcagtgact gtcaagaatg gaagaagaaa tatccgacct atgattttca
     8641 gcaccgtgcc ttttttgtgt acgatgaaaa tatgaaggcc tggctcaatc aatacaagtt
     8701 tatgggagat atccgactag caggcacctt tgcatataaa tggacgcaga taaaaaaaga
     8761 atacccgaca tacatctatt gtccaatacc tttatctgaa aaaaggcgaa cagaaagagg
     8821 attcaatcaa gtaagcgaga tgttgaaagc agcaagaatt ccttttcaga tgctactcaa
     8881 aagagagaag catctgctgg ctcaagcaaa aaacacgcga aaggaaagat tggagatgcc
     8941 tcaacctttt gaacttgcag tcaccttttc taagatacaa aataaaaaaa tattgattat
     9001 tgatgatgtc tatacaacag gacagactct tttccacgca gcagattgtt tgcagatcgc
     9061 acagccgaaa atcatccgaa ctatttcttt ggcgagatga attagatgtg gaaatttgat
     9121 agcgatttaa tttgcaaata acctagagtt cgatataata gaattaagaa gagggaaaga
     9181 gtggtccttc tccttcttga ttgtggtaga cgaaaggggt aatttttatg tttagatata
     9241 atgtacgcgg cgaaaatatc gaagtaactg aagcgattcg cgactacgtt gagaaaaaag
     9301 taggcaaact agaacgctat ttcagtgacg cacccgatgc aacggcgcat gtgaacttaa
     9361 aagtttatac agaaaaaaca gcaaaagtgg aagtaacgat cccattacct tatcttgtat
     9421 tacgtgccga agaaacttct ccagatttat acgcaagtat cgatttggtt gttgacaaat
     9481 tggaacgcca aatccgcaaa ttcaaaacaa aaattaatcg taaatcccgt gaaacgggca
     9541 tgaatactgc aaatgctgct gctttattca atgaagagga cgaaaacgaa aatgattctg
     9601 aattagatat cgtacgtacg aaacgccttt cattgaaacc aatggatagt gaagaagcag
     9661 tcttgcaaat gaacatgctg ggacataact tctttatttt tgaagatgca gaaacaaatg
     9721 gtacaagtat cgtttaccgc cgtaaagatg gaaaatacgg actgattgaa acagactgat
     9781 cagccttact taaataacaa cgaaaacttg cagcagctac tgacagctgc cgcaagtttt
     9841 tttgagtttc ctcctctttt agatgaaata tgaataaatt atgaagttct tactttaata
     9901 cgcttaagat atttcaatta tctataacta atgataaaat gaaaagtaaa gtctacatag
     9961 tctggataat acacagaagg aaaaggagat tacacaacgc atggccaatt tgattcgttc
    10021 acttatcgaa aacgataaga aagaactaaa acgtttagat agcattgcaa aaaaagttga
    10081 agcatacgct gaccaaatgg cagcattaac tgatgaacaa ttacaggcaa aaactgctga
    10141 attcaagggc agataccaaa aaggagaaac attagatcaa ttacttccgg aagcttttgc
    10201 agtcgtccga gaagcagcaa aacgtgtatt aggtttatat ccataccacg tacaattgat
    10261 gggtggaatc gtgcttcacg atggaaatat ccctgaaatg cgtactggtg aaggtaaaac
    10321 cttgaccgca acgatgccag tatatctaaa tgctctgact ggcgaagggg tacacgtagt
    10381 taccgtcaat gaatatttag caacccgtga ctcgacggaa atgggcgaac tttataattt
    10441 cttaggatta acagtggggt tgaatatcaa ctcaaaatct tcggatgaaa aacgcgaggc
    10501 ttataattgt gatatcactt atagtacgaa taatgaatta ggatttgact acttgagaga
    10561 caatatggtc gtttaccgcc atcaaatggt acaacgtccg ctgaattatg ccattgtcga
    10621 tgaagttgac tcaatcttga ttgatgaagc gagaacgccg ctgatcattt cagggcaagc
    10681 agaaaaatcc acagctttat atacaagagc agacaacttc gtgaaacgtt tgaaagaaga
    10741 agaagattat aaaatcgatg tacaatcaaa aacaatcagt ttaaccgaag cagggatcga
    10801 aaaagcagaa gaaacattcg gtttggataa cttatacgac attgaaaata ctgcattgac
    10861 ccatcacttg gatcaagcat tgagagccaa ctatatcatg cttttagata tcgattatgt
    10921 tgtccaagac ggaaaagtac tgattgttga ccagttcact ggtcggatca tggatggacg
    10981 ccgttattca gatggacttc accaagcaat cgaagctaaa gaaggcgtag agatcgaaga
    11041 cgaaacgaaa accatggcga cgatcacttt ccagaactat ttccgtatgt acaagaaact
    11101 tgcgggaatg actggtacag ctaaaacaga agaagaagaa ttcagagaaa tttataacat
    11161 ccaagtatac cagattccga caaatcgtcc ggttatccgt gatgatcgtc cagatttgct
    11221 ttacccaaca ttacaaagca agttccacgc tgtcgtgcaa gatatcaaag atcgctaccg
    11281 caaaggtcaa cctgtgttag tcggaactgt tgcggttgaa acatctgagt tattatcaga
    11341 tatgctgaat caagaacgta ttcctcatga agtgctgaat gcgaaaaatc actttaaaga
    11401 agcagagatc atcatgaatg ctggtcaaaa aggtgctgtg acgattgcta ccaacatggc
    11461 tggtcgggga acagatatca agttaggact tggggtaaga gaacttggtg gtctagcagt
    11521 tatcgggaca gaacgacatg aatctcgtcg tatcgataac cagcttcgag gacgtgcagg
    11581 acgtcaagga gaccctggta tgtcacagtt ctacttgtca ttggaagatg atttgatgaa
    11641 acgattcggt tcagaacgaa tcaaatcttt cttagatcgg atgaagatcg gtgaggaaga
    11701 tgctgttatc caaagcaaga tgctgacgaa acaagtagaa tctgcacaaa aacgtgtaga
    11761 aggaaataac tatgacacac gtaaaaacgt cttacaatac gatgatgtga tgcgtgaaca
    11821 acgtgaagta atctataaac agcgacaaga agtaatcatg gaagaaaaaa gcttatccaa
    11881 gccactaatg aacatggtca aacggacaat cagtcgtgta gtagatgcgc atacacaatt
    11941 agagaaagaa aattggaatt tggaaagtat catcgatttt gccggcagta ctcttgtcca
    12001 tgaagatagt attactcttg cagatatcga aggaaaaaca gctcaggaga tcaaagagta
    12061 tctaaacgaa cgagcacaag aagtatttaa taccaaagcg gctcaactaa atggtccaga
    12121 gcaactgttg gaatttgaaa aagtcgtgat cttgcgtgtt gtggactcta aatggacaga
    12181 ccatattgat gcaatggatc aattacgtca gtcaatcggc ttacgtgctt atggacagaa
    12241 caatccatta gtcgaatatc aaacagaagg ctataagatg tttgaagata tggtaggcgc
    12301 catcgagtat gaagtcactc gaatctttat gaaagctgag atccgtcaaa acgtacagcg
    12361 tgaacaggtt tctcaaggaa cagcttctca ctcagaagac ggagatgcca aagaaaatag
    12421 taatactagc gcgaaaaaac agccaatcca tgtgaacaag gtcggaagaa atgatccttg
    12481 tccttgtgga agcgggaaaa aatataagaa ctgtcatgga aaaaatgcaa actaatttct
    12541 gacagcagga ttggtgagac aaattctttt tttaagaatt cgtctcacct tctttctgtt
    12601 atttgctgat tctgttagac tagatataat gaaaaaagta tagtgaaaga aggaaaaaac
    12661 atggaaatat ccgaaattcg aaatctcctg acagaaatgc aggaaaaggt cacaagcttc
    12721 aggaggtctc tttgacttag accagctgga agaagacatt gcggaagcag aagcaaaaat
    12781 ggctgaacct ggtttttggg atgatagcga agctgctcaa aaagtgatca gtgaaaacaa
    12841 tgcaaataaa gaaacttatg atcaattcca ttctcttgct gaagaactgg aagaaatcga
    12901 attgatggtg gagatgttgc aggaagaacc tgatgcagcc atgcaagaag aagcagaaac
    12961 acgtatcaat gcgctagatg aaaaaatgaa gacatatgaa ttatctatgt tgttagatgg
    13021 tccttatgat cgaaacaacg ccatcgttga attgcatcca ggggctggcg gaacggagtc
    13081 ccaagattgg ggcagtatgc ttttacgtat gtatacacgc tgggcagagc agcatgggta
    13141 tcaagtagag acactagatt atcaagcagg tgatgaagca ggaatcaaga gtgtgaccct
    13201 actgatcaaa ggacacaacg catttggtta tctgaaatca gaaaaaggtg ttcatcgcct
    13261 tgtacgtatc tcgccttttg actcagcgaa acgacgtcat acttcttttt gttcggtaga
    13321 tgtgatgcca gagcttgatg aaacgatcga tatagaaatc aatccagatg atttgaaaat
    13381 cgatacgtac cgagcaagtg gtgcaggtgg tcagcacatc aataaaacag aatctgctgt
    13441 acggatcact cacttgccta caggaacagt agtagctagt caggcacaac gttcacaatt
    13501 gaaaaaccgt gagcaagcga tggggatgtt aaaagctaag ctttatcaat tagaagtgga
    13561 aaagaaagaa caagaagcag ctgcacttcg aggagaacaa aaagaaatcg gctggggttc
    13621 acagatccgt tcttatgttt tccatccata ttctatggta aaagaccatc ggacaaacgt
    13681 agagacagga aatgtccaag cagttatgga cggtgacctt gatttattta ttgacggcta
    13741 tttaaaaatg catctacaat aagaacccat tgttaaattg aaataaaatt gtaagatttt
    13801 gcaagcatgt tgaaacattg ccatgctata atagctaaag actgaaaaag atatggagag
    13861 aacgccatga ttgaaatgaa ggatgtaatg aagaagtact caaatggtac gaccgctatc
    13921 cgcaatctct caattgtcat cgaacaagga gagtttgtct atgtggttgg tccgtctgga
    13981 gccggtaaat ctacattcat caaattgatg tatcgagaag aaaaagcttc aaaaggaact
    14041 ttgaacgtcg caggtcatga tctaatagca atcaaaaacc gcgaagttcc ttatctacgc
    14101 agagaaatcg gcgtggtgtt ccaagactat aaattattac caagaaaaac agtatatgaa
    14161 aatgttgcgt acgctatgca agttatcggc agaaaacctc gggatatcaa aaaacgagta
    14221 atggaagtgc tggaccttgt tggtttgaaa cacaaagttc gagtctttcc tagcgaatta
    14281 tccggtgggg aacagcaacg tgtctctatt gctcgggcaa tagtgaatac gcctaaagta
    14341 cttatcgcgg atgaaccgac aggaaatctg gatccagaaa actcatggga aatcatgaaa
    14401 ttattagatc ggatcaatgc ccaaggaact actgtcgtga tggctacaca taacagtacg
    14461 atcgtaaata cgattcggca ccgagtaatt gctatcgaaa acggccgcat tattcgagat
    14521 caagcggaag gggaatatgg atacgatgat tagaaccttt ttccgccatt tattagaaag
    14581 tatcaagagt ttgaaacgta acggctggat gacagttgct tcagtcagtg cggtaacgat
    14641 cacattgact ttagtcggtg tattcatggc agttatcatg aacgcaacta aattagctca
    14701 agatatagaa ggaaacgttg atgtctctgt attcgtagat atcggtacaa aagacgaaga
    14761 gatgaaaaag ctagaaaaag aattgaatga cttagatcat gttaaaaaag ttgaattttc
    14821 aagcaaagaa caggaattga aaaaaatcca aaacgaaatg ggtgattcct ggaaattgtt
    14881 tgaaggtgac aataacccgt tatatgatgt gtatgtagta agtgctactg atccttctta
    14941 tacaaaacaa gtagcagaag aagcagcaga tttgaagaat gtttctcgtt ctgattacgg
    15001 tggagcttcc tcagatcgga ttttccaaat cgctggtgca gttcggacat ggggattagt
    15061 tgcagcggca ttgctgctgt tcgtagcgat gtttctcatt tcgaacacga ttcggatcac
    15121 gattttgtct agacagcgtg aaattcaaat catgcgttta gtcggtgcaa aaaatggata
    15181 tattcgctgg ccgtttttcc ttgaaggtgg ctggatcggt ctgatcggtg cgattcttcc
    15241 gattttgatc atcacatttg gttatgcatg gtttttccaa ttgatcaatc catcattatt
    15301 acgttcccat tattcattga ttcatccaca aaatatcgtt tggaaaatca atcttttaat
    15361 ggtcggcatt ggtgtgatca ttggttcact tggctcgatc atttctatga gacgtttctt
    15421 gaaattctaa taccacaata taaataaaat gagaaagttg gacagtttcg ttccagcttt
    15481 ctttttttat tggctaggag aatagaagga agcggctttt ttccctttac tttaaaaaac
    15541 aacttgggta ttcttaagtt ggtagaagaa gaggtgaagc cgtgaaaatt atcgttgaca
    15601 atttttttac gatccttttg attatgaata ttttgctttc ctttatcatc gtttttcgag
    15661 aaagaaagga aactgctcaa acatgggcat gggtgctcgt tttgatgttc attccagttg
    15721 taggatttat tttatatatt tttttaggaa gagggatttc caaagagaaa atctttgatt
    15781 tgaagatcca agggaaaatc ggtaagaacc tggaaattga agaagacaaa caggcattga
    15841 tgcgagggct ttatcctcat ccgcctactg gacaagtaga tgtgaaacaa ttgatctata
    15901 tgctcacggt atttgaaagt acgctctata cgactaaaaa tgaaatcact ttatttacag
    15961 atggtcgtga aaaattcgat gcgctgattg aagatatcaa gcaggcagaa gaccatatcc
    16021 acttccagta ttatatttat cgcagtgatg cattaggtga agaagttcga gatgcattga
    16081 cagaggcggc aagacgaggg gtaaaagtca gagtccttct tgatgcatgg ggttccacac
    16141 aagtttcttc cagctttttt cagaatttga aaaaagcagg cggagaagtc gcatttttct
    16201 ttcctctatt tgttccgtat attaatcctc ggatcaatta tcgcaatcat cgtaaaatcg
    16261 tagttattga tgggaaaatc ggatatacag gtgggttcaa tgttggaaat gaatatctag
    16321 gattggtaaa gaaatttggt tattggcgag acaatcattt gcgtatttac ggagaagcgg
    16381 tgtatacctt gcaaaaccgt tttttgatgg actggaattc tcagcataca aaagaagtag
    16441 gctattctcc caaatttttt ccgtccattc actctactgg tgatatagct gttcaaatcg
    16501 tgacaagcgg accagatacc gaacatgaac aaatcaaaat gacttatttg aaaatgattt
    16561 cgttagccaa acgggagata ttgatccaaa cgccttatta cataccggat ggatcgattc
    16621 atgaagcact gaagttggct cttctttcag gcgtaaaagt tcatatccaa atacctaaca
    16681 aaccagatca tcttctcgtt tactgggcaa cgtattcttt cgctgcagag ctaatcgagt
    16741 atggagcaag gatcgaaaca tatgagaatg gatttattca tgcaaagacg atgattatcg
    16801 atggtggcat tgtttcagtt ggctcagcaa atatcgatgt tcgttcattt cgcttggact
    16861 ttgaggtcaa tacactggtt tatgatgaac gaatggcttc acgtgtaaga aaagcttttt
    16921 ttgaagactc gaaaatttct acgcatctca caaaagaaat gtatgaaaac cgaggaataa
    16981 tcatcaagat gaaagaagga ttagcaagat tgatttcgcc gctcctttaa aacataaaaa
    17041 ggacatgaga accatcaaca gatggagatc tcgtgtcctt ttctaacggg gccatttctg
    17101 agagtacgtc agaaatggag aaagcgtctc gcatgagcga aattaacttt ggggtatctc
    17161 ttgttttttg gggaaagcaa gaaataagct aatatatgct attaaaagag acacatttca
    17221 aagccagtat agcatagaaa cttttaatga gatagttttt tttacaatta tgagaattta
    17281 ttttgttatt taatgatttt gattcgtttt catcaagtaa tgaaaatgat aaaataaaca
    17341 tactttagga ttaaaggaga tttctaatga aaaaacttaa attattctta ccaataatag
    17401 gattagctat tcttttatca ggctgttcaa agtggattga tcgaggagaa tccattacgg
    17461 ctgttggctc ttctgcttta cagcctttag tagaaacagt tgctgaaact taccagacag
    17521 aaaatcctgg aaaattcatc aatgtacaag ggggcggaag cggaactggt ttgtctcaag
    17581 tacagtcagg agcagtcgac atcggaaact ctgatttgtt tgcggaagaa aaatcgggga
    17641 tcgatgcctc agcattagtc gatcatcgag tagcagttgt tgggatcact cctattgtga
    17701 acaaggatat tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta tttacaggcg
    17761 agatcaaaaa ctggagtgaa gtcggtggaa aagatcagcc agtagttata ttgaaccgcg
    17821 cttcaggaag cggaacccgt agcacgtttg aaaaatgggt attggacgga gaaacagctg
    17881 ttcaggcaca agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc gacacacccg
    17941 gtgcaatcag ctatgttgct ttttcttatg tttccgatga tgtagatacg ttgaatgtta
    18001 acggtgtaga accgacagat gaaaatgtga caacgaacaa atggacgatt tgggcatatg
    18061 agcatatgta cacaagagat catccaaaaa aactgacaaa agaattttta gactatatct
    18121 tatctgatga agtacaagat aacatcgttg gagaactagg ttatatccct gtttctcata
    18181 tgaaagtcga acgtgattgg caaggaaata tcgttaaaga gtaatcttta cacaaaattt
    18241 acaaacttag ctaaactttt acatgttatt aaaaccaaat tgatgttcaa tttgtacact
    18301 gagtgagtat gttaaacctg attaaggggg agtcatctgt ggaagatgtg aaaaaagtat
    18361 tattaacaaa atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc agttttttat
    18421 gtatcgcgct gatcgtgttg gttgtattat ctatttttta ttttgtagct agtaaaggat
    18481 tggccacctt ttttactgat aagatcaatg tatttgattt tctgtttggt acagattgga
    18541 atccaagcca aatcggagca aatgggaaac caatggtagg ggcattgcct atgatcacag
    18601 gttcgtttat tgtgaccttt ttatctgcta tcgttgccac gccatttgcc attggtgcag
    18661 cagtattcat gacggagatc tctcctaaaa acggaacgaa gatcttacag ccggtcatcg
    18721 agctgcttgt aggtattcct tctgtcgttt atggttttat cggtttatca gttatcgtgc
    18781 cttttgtcag aagtattttt ggcgggactg ggtttggtat cttagctggt acatttgtgt
    18841 tgttcgttat gatcttgccg actatcacaa cgatgactgt tgatgcatta aaggcagtgc
    18901 cacggcacta tcgggaagct tcattagcgc ttggtgccac aagatggcaa acaatctaca
    18961 aagtcgtgct acgagcagcc gtgcccggga ttttaacagc agtcgttttt ggtatggctc
    19021 gtgcgtttgg tgaagcctta gctatccaaa tggtcatcgg taatgcagca ttgatgccaa
    19081 caggtcttac tactcctgct tctacattga cgtccatctt aacaatggga atcggaaata
    19141 caatcatggg aacagttgaa aataatgtgt tatggtcatt agcgctgatc ttgctattga
    19201 tgtcattatt ctttaatatc gtgatccgta tgattgggaa gaaaggagag ctgaaataat
    19261 gaacgcaaaa cgctcagata aaattgctac aggtgtttta tatatagttt cggggatcat
    19321 cgtattgatt ttagcagctt tactacttta tatcttagtt cggggaatac cgcacatttc
    19381 atggtccttc ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa tcgggatcca
    19441 gctatttaac tcgatttatt tgcttttgat cacgatgatc atcagttttc ctatttcttt
    19501 aggtgcgggt atctatcttt cagaatatgc tggaaaaaac tggctaacag atgtgattcg
    19561 cacgtcgatt gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat tcggtttctt
    19621 ggttttcgtt attcaattcc agtatggttt ctcgattatt tctggtgcat tggctttgac
    19681 tgtattcaac ttgcctcttt tgactagaac agttgaggag tctttacaag cggtccatta
    19741 cacacaacga gaagcaggat tggccttagg tttgtcacgc tgggaaacag tgataaaagt
    19801 ggtggttcca gaagcgacac cagggatttt gactggtgtg atcctaagtt ctggaagaat
    19861 ttttggtgaa gcagctgcat tgatctatac ggctggacaa agtgcacctg cgttagattt
    19921 tacgaactgg aatccattaa gtgtttcaag cccgatcagc attttccgtc aagctgaaac
    19981 attagctgtc catatttgga agatcaatac agaaggcacg atgcctgatg gtgtttctgt
    20041 ttcggctggc gcttctgccg tgttgattat tgctgtttta ctgttcaact tcggcgctcg
    20101 tgcgattggc aaacgattat accgaaaaat gacttcagcc taaggagaag aagcaaaatg
    20161 aaaaaatata actggaatga aacaaatgtc atcaccatgc caaaagagaa agaagtagca
    20221 ctatatacgg atgatctaca tgtctggtat ggcgacaatg aagcaatcaa aggagtggat
    20281 ctggaatttg aaaaaaataa gatcactgca ctgattggtc cttccggctg cggaaaatct
    20341 acgtatcttc gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa aatcactggg
    20401 aaaatcatgt atcaaggcgt agatattaat gcgcctcaag tggatgttta tgagatgcgc
    20461 aaacggattg gcatggtttt tcaacgtcct aatccgttca gcaagtcgat ttatgacaat
    20521 attacatttg ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga tgaaatcgtt
    20581 gaaacaagct tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt ggacaaaagt
    20641 gccttggctt tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc gatcgcgatg
    20701 aaacctgata tcttgctgct agacgagccg gcaagtgctt tggaccctat ttcgacagga
    20761 acggttgaag aaacacttgt aaacttgaaa gaagactata cgatcatcat cgtgacgcat
    20821 aacatgcaac aagcagctcg tatcagcgac tatactgcct ttttctattt aggaaaagta
    20881 atggaatatg acaaaactaa caagatattt accagaccaa aaattcaggc aaccgaagat
    20941 tatgtgtccg gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga gattatttca
    21001 tctaaagatc ttcatctgta ttatggaaag aaagaagcac taaaagggat cgatctaagc
    21061 ttcaatcaag gggaaatcac tgcgatgatc ggtccttctg gttgcggaaa atccacttat
    21121 ctgcgttctt tgaaccggat gaatgacctg attccgaatg taacgatcac cggaagtgtt
    21181 ttatataaag acaaagacat ctatggtcca aaaacagatg ttgttgaact aagaaaagaa
    21241 atcggcatgg tattccagca gccaaaccca tttccttttt ctatctatga aaatgtcatc
    21301 tatggattga aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt agttgaagaa
    21361 agcctgaagg cagcgtctgt ttgggatgat gtgaaagaca aattgcataa aagtgcttta
    21421 tctttatccg gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc agttaatccg
    21481 gaaatcatct tattggatga accaacaagt gcgcttgatc ctgtttctac tgggaaaatc
    21541 gaaagtatgc tgttagaatt aagagagcgg tatacgatga tcatcgtgac ccataatatg
    21601 tctcaagctt cacgtatttc agataagacg gcattctttt tagatggtca cttgatcgaa
    21661 tacaatgata cgaagaagat attcatgaat ccagaaaaac aagagacaga agattatatt
    21721 tcaggtcgat ttggataagg aggaaacgga atgctacgta cacaatttga agaagaattg
    21781 ctgaatctcc ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc cgtgcacaag
    21841 tcagttcgtg catacatcaa acacgataaa atcttagccc aagaagttat cgaaaacgat
    21901 ataaatatca ataacatgga aacacgcttg gagaagaaaa gttttgaaat gatcgcattg
    21961 caacagccag ttacaactga tttgcgtatg atcattacgg tcatgaaagc tagctcggat
    22021 ttagaacgta tggccgatca tgcggtgtct gttgctaaat ccacgattcg cgtaaaaggg
    22081 cagacgagaa taccggaaat cgaaaaagag atctccgata tgtccgatta tgtgaaaaaa
    22141 atggtggaca acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc acgtacgatc
    22201 gccaatatgg atcaaagagt caatgactat ttcaatcgaa tctataatgc aacaatcaaa
    22261 aatatgcagg aaaatcctga gacagtcatc agtggaacag actacttgaa tgttgccagt
    22321 tatctagaac ggatcggaga ctatgtgaca aacatctgtg aatggatcgt ctacttggct
    22381 acagggaaaa tcactgagtt aaatacgaac cacaatgaga ttttctaaac tgaagctgtg
    22441 attatgccgt ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa aagctgttct
    22501 gcatcaagta ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg
    22561 acttattacc gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa
    22621 aacatgtcac aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt
    22681 agcatcatca ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagcc
    22741 gctttatatg aagtacctgt catcgagata gaaaaagtac gaataaaaga ggatcatcaa
    22801 ttgattacag gaaaactgat gaacacggat caaaaaggag aatcgattta tttatcggtt
    22861 ccttatcaaa aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc
    22921 caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa atgatggctg gcttttcttc
    22981 ttcacaagta tcttcattgg cgccatgttg cttattggtg gaaaacaggg tctatttgct
    23041 ttaggaagtc tcatcatcaa tatcgtttta cttttacttt tgttgctcat ctttactaaa
    23101 acagaaggga tttctctatt aaatatatct atcctgttcg tcgttatagg gatgattatt
    23161 agcatattgg ctttagatgg atggaataga agcagtataa tcaaaatttc agctgcagtt
    23221 acgagtgttt ttttagcatt ttttatttgt cttttgacaa tgaatcattg gaaagaccaa
    23281 ggactgcgct atgaggaact gaattatctg acacgaccgt atcgttctgt ttttctttct
    23341 agcgtactga ttggaacagc tggaggaaca ctcgataccg ttatcacagt cattgcgaca
    23401 ttagaagaat tgactaagcg acaaccagaa ataacagcga aacagttatg gctttcagga
    23461 aggcaagtgg gtcgagatgt gattggctcg atgaccaata tccttttgtt cgtctatatc
    23521 agtgggtcag ttccatcgct tcttttatat ttaggaaatc aatggtcgtt caaagaaacg
    23581 atagaacagc atttatcatt ggaattttta cgcgtcattg ctggcagctt aggaatagta
    23641 ttatcgatcc ctatctcggt cctctttttt ctgactgtaa ggaggctgaa acgatgaatg
    23701 tacttattat acttgttggg attttagcaa tcagcgtgct acttattggc ggtacgcaag
    23761 gtatgtatat tcttttaggc ttattcatca atttagggat ctttttcctg ttgttattcg
    23821 gttatcatca gaagtggccg atactggcat tgtcggtcat aggattttta ttgattgctg
    23881 tggttatctt attttttatc aacggttata atctaaaaat gcgtgcagct tttgtgagta
    23941 tactgatctt tttattttgt ttcctactat tgcttcctat cactgatttt ttagcaatcc
    24001 aaggttttac atcggtagaa ctagaagaat tatctggctt agataagact ttagcgattg
    24061 attttagatt acttacgaga tcgttgcttc tgattagtct tagtggtgct gttttagatg
    24121 cgagtgtagc aatttctagt gggacattcg aagtatatca ggcaaatccg caattatctt
    24181 tttaccaatt gcgccattct agtttcgcta ttgctaaaaa aatattggcg tcaacagtaa
    24241 tgacacttct ttttgcattc atgggaagtt ctttagcgtt gatcctctgg tttattgatt
    24301 tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt tgttctagaa tatacgatgg
    24361 ctattcttac cacattgtcc gcactacttg ttcttccttt aacctgcgtg actacagcat
    24421 atctctttac aaaaaagaaa gaacaactca agatggagta aaagttacaa cttaagtcct
    24481 atgacatttt tactgaatca gtgcataata tggatgtaag gaaaagcttg caaacaattt
    24541 tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat tttagattta gtgaaaaaag
    24601 gaatcctttc gactgaagaa ggcttagatt tattagaaag catggcaact gaaaaagacg
    24661 aaaagcaaat caaaaaagaa gcagacaagg taactgctag tcataaagaa aaagatcagg
    24721 caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga aatttctgag ccagttgatc
    24781 caaaggaaag agaaagacaa gatcaagaaa acttagaaaa gatcttagat gaactagcaa
    24841 ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa tgctcaattc gctgacaata
    24901 aggcagcacg caatgagaaa caggaagcat tgatgcagct gaatacaaaa gaagaattag
    24961 gcgagttgac agaagaagaa ttagcacagc gtcagacgtt agaagcagaa atcaaagaat
    25021 tagaagctag tggcgataca ctgttagaag aacaattgaa attagaagca gaattaaaag
    25081 atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt tactgataag tttgaattgc
    25141 cagatgattg gaaagatcaa gcaacagata cactgaatca agtaggcgaa aaaatgtcag
    25201 aagctggatc acagttaggc aaattcttga agaaaacatt ccaaactgtt tcagaaacag
    25261 tgaatgacaa catggaatgg aaagatgtca gcttacgtgt ccctgggatt gcgacaacga
    25321 aatttgagca tgaattttac tatgaagctc ctgcagcaag tatccttgat atcaaggcag
    25381 caaacggaaa cgtgacgtta aaaacgtggg acagcaacga tgtgaaagtt gaagctaaga
    25441 tcaaacttta cggaaaaatg ggtgctgaac catttgaagc attctctgaa cggagccaga
    25501 ttgaggttaa tgaagatcat atctccttcc aaattccaaa taaacgtgtg cgtgcagacc
    25561 ttgttttcta cttacctaaa cgagtatacg accacgcagc tattaaactt ctaaatggca
    25621 acatcatgat tgaaacattg gaagctaaag atatttatac aaaatctacg aatggtaaca
    25681 tcatcgtgga ccaattaact gcaacgatgc tggaagtaga aggtgtaaac ggcaatatcg
    25741 atattcgaaa cgggaacatc ttagattcta ttatcgaaac agtaaatggt acagtgacat
    25801 ttggtgcgac agcagaaaac ctttctgtgt ctttggtaaa tggtgatgta cgtcttacga
    25861 ttaaagaaga taatttgaaa aaagtagaag caagttcagt gaacggaaat gtcaaagtcg
    25921 ctttaccaga tggcatcggt ttggaaggac atgctaaaac aagtcttgga agtatcaaca
    25981 gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga acggacaaac caaatgttgc
    26041 aattccgtcg tgtttcagat ggtgaaatcg cgcaagtgca actttcaacg acaacaggaa
    26101 gtatctattt aaaagataca gataaataaa gaggttgtga aagagatgtt cagccttgag
    26161 caataagaag cgattttgta aaatagcttc ccctatttta caaaattgtg ccttattgcc
    26221 gatagtctat ctcttgaaca ccgtttacca agagattatg aacctgccaa ttatcgccga
    26281 gtcacaagga ataatttcag aaaaagctcg tcacgtttta tgaatatggt aatttgtgac
    26341 cgagaatttt gcagaaagac accgattaag aagaaggttg tcacaacgat tttcttcatt
    26401 taaaatagta gaacagaggt gagacatgat gaaaaaaaag ttgacaaaat ctaataaaaa
    26461 tgttgttttg acagggactt tagcaggaat aggagaatac atcgggattg atccgactgt
    26521 tatccgtgtg ctttatgtat tcctgagctt agttgctttt ggaagtccaa ttattttata
    26581 cattttatta gctttgatta tcccatctgc gcgttctgca cgaacaaact atggacataa
    26641 caatgcatat tatgaaaaaa acaattatcg tgaacaaact cgtgaacaaa caaaaaaacg
    26701 caaagaagcg gaaaaaatcg atgatgacga atggagtgac ttttaatgtc gtactttcaa
    26761 cgtattttag ttaatacgtt aacattcata tcattggctg ttctttttcc tgcgatggtc
    26821 catgtgagca gtatttggac ggccgttctt gccagcttcg tattgtctgt gttgaatatg
    26881 tttgtcaaac cgattttgac gatactgtcc ctgcccttta cattagtcac attgggattg
    26941 tttacgtttg ttatcaatgc agcgattctt aaaatgacct ccttttttgt gggagcagaa
    27001 cattttagtt tttcttcatt cggtgcagcg ttgttagtag ctatcttgat gtcgcttgtc
    27061 aatgtaattg tcagcgaaca taacagtaga aaataaaaga aagctgtgcc gaactatcgg
    27121 cgcagttttt ttatttagaa tcaggaatgc gttttctatt acattggtaa ttaaataaaa
    27181 acgttttttt taattggtag tacttttggc tagacaatga taaaatgata gagaacactc
    27241 taatagaaat gaggtagcat gaatgtcaga agttgtaaaa gttagccaat tagtgaaaaa
    27301 attatctttg gaaatcgtga caggcgacga gaaaagctta gaccgtgtca tcgtaactgg
    27361 ggacatctca cgcccaggac tagagttgac tggttatttt aattattatt cccataatcg
    27421 tttacagcta tttggcagta aagaaatcag ttttgcggaa cggatgatcc cagaagagcg
    27481 tttgatcatc atgagaagat tatgtagtga agatatgccc gcatttatta tttcaagagg
    27541 attaccagct ccagaagaaa tgatccaggc agcaaataaa aatgggatag ctgtactgcg
    27601 ttctcccatc tcaacttctc gtttattagg agaattatcc agttatttag atggtcgcct
    27661 tgcccctcga acaagtgtcc acggtgtttt agtggatgtt tacggattag gtgtactgat
    27721 tcaaggtgac agtgggatag gaaaaagtga aacagcgttg gagttgatca aacgcggcca
    27781 tcgattgatc gcagacgatc gagtagatgt ttatcagcaa gatgaattaa cggtgatcgg
    27841 agaaccgcct aaaatcctgg aacatctgat tgaaatccga ggaatcggga tcattgatgt
    27901 aatgaatctt tttggtgcga gtgcggtacg tggctctatg caagtccagt tggctgttta
    27961 tctggaagca tgggcaaaag ataagaaata cgaccgtctg ggctctgaag acacgaccgt
    28021 tgaaatcgcg gaagtgggca ttccacaaat aaaaatccct gtcaaaacag gacgaaacgt
    28081 tgcaatcatc attgaagtag ccgcgatgaa tttccgtgca cgtacaatgg gctttgacgc
    28141 aacgaaaaca tttgaagaaa gattaagtcg cttgattgaa gaaaactcag gcaacgacta
    28201 gcaaggagtg acaatatgtt agcacaaatc aatcgagttg cttttgagct tgtagggatt
    28261 cctatctact ggtatgcatt gatcatcgta tcaggtatca ttatcgctat gtggcttagc
    28321 agcagagagg ctgttcgggt aggattaaaa gcagatgatg tgacagattt tatgttgtgg
    28381 ggattgccta tctccattat tggcgctcgc ttatattatg ttttatttga tcttccccag
    28441 tatatagctg atccaatcca aatattcaat atccgttcag gaggcttagc tatttatggc
    28501 ggactgattg caggcgcgat cacgctgtat ttttttacta aatatcattt tatttctttg
    28561 tggacttttt tagatatcgc tgcaccaagt gtattattag cacaggcaat cggtcgttgg
    28621 ggaaatttca tgaaccacga agcatatgga ccagacacga cgcgaagctt cttagaaagt
    28681 ctgcatttac cgcaattcat cattgataat atgtatatcg aagggatcta tcgtcaacca
    28741 acatttcttt atgaatcact ttggagtttg attggattta ttttgctttt gtttttacga
    28801 aagaaaccac accttttgaa aaaaggcgaa gtccttttat gttatctaat gtggtatagt
    28861 ttcgggcgtt tctttattga aggattacgt acagacagtc tttacttttt aggtgtgatc
    28921 cgtatttctc aattattatc tgctgtgtta tttgtcggta cattgattct atttatttgg
    28981 cgcagaaaaa aaggaaattt accggattat gaccgctcat taggaaaaaa tcaacaaatt
    29041 atctgatttt tagagcgtta aaaatgaaaa aaatttcagg agtggtaaaa tgaattatag
    29101 agtagcggtt ttaggaccag gctcttgggg tactgctttg gcacaagtcc tcgccgaaaa
    29161 cggacatgac gttcggattt ggggacatcg tgcttcacaa gtagaagaaa tcaacaccca
    29221 acacacgaat caacgttatt taccagatca ttatctaccc gattccatcc aagcattcac
    29281 caatatggaa gatgcagtaa aagacgcaga tgcggtgcta ttcgtcattc caacgaaagc
    29341 aatacgttct gttgcaaaag aactagtgcc taaattgaat acaaagccag tgatcatcca
    29401 tgcaagtaaa ggattagaac agggaacaca taaaaggatc tctgacatct tgttagagga
    29461 aatcccagca gaaaaaagaa aagctgttgt tgttctttct ggaccaagcc atgcagaaga
    29521 agtagcaaaa catgacatca ctacgatcac agctgcaagt acagatgcaa aagcagcaaa
    29581 atatgtacaa gagctgttca tgaataatta ttttcggatc tataccaatc ctgatgtgat
    29641 cggtgtagag atgggggcag ctttgaaaaa tattattgct attggtgctg gcgctattca
    29701 cggcttaggg tttggcgata atgcaaaggc agcaatcatg acgcgcggat tagctgagat
    29761 cagccgttta ggtgtagcaa tgggtgccaa cccgctgacc tttatcggat taagcggaat
    29821 aggcgatcta gtcgttactt gcacaagtgt tcattctagg aactggcgcg caggcaactt
    29881 gttaggacaa gggcagcccc tagaagaggt gctagccaat atgggaatgg tcgttgaagg
    29941 tgtgaatact acccaagcag cgatggaact agcccaaatg atggaaatcg aaatgcccat
    30001 cactcaaaca atctatgaag tgctgtatga acaaaaagaa atcaaaacag ccgcaaaaga
    30061 aatcatgtta cgtgatggaa aaaaagaaaa tgaattctca ttaacaattt tttgaaggag
    30121 cgaatgtata tgaaagttaa aaaagcagtt attccagcag caggattagg aacaagattt
    30181 ttaccagcaa caaaagctat ggcaaaggaa atgttgccaa ttgttgataa accaacaatc
    30241 cagttcatcg ttgaagaagc gttgaaatca ggtatcgaag acatcttgat cgttacagga
    30301 aaagctaaac gaccaatcga agatcacttt gattcaaata ttgaattaga aacaaaccta
    30361 agtgaaaaag gaaagaccga attattgaaa ttagtagaag aaacgacaga tgtcaacttg
    30421 catttcatcc gtcaatctca tccaaagggt ttaggacatg ccgttcttca agcaagagcc
    30481 tttattggaa atgaaccatt tgtcgttatg ctaggcgatg atataatgga agacgaagta
    30541 ccattgacac agcaattaat cgatgattac gaacgtactc atgcttctac gatcgccgtt
    30601 atgcaagttc ctcatgatga aacttcaaaa tacggaatta tcaatccagg agaagtattg
    30661 gaagatgggt tatacaatgt caaaaacttt gttgaaaaac cagatccaag caaagcacca
    30721 agtgatttag ctattattgg acgttactta ttgactccag aaatttttga tgtattgtcc
    30781 gagcaacaac caggagccgg aaatgaaatc caactaactg acgcaatcga tacattgaat
    30841 aaaacacaac gcgtatttgc ccgtaaattc acaggtaaac gttacgatgt cggtgacaaa
    30901 tttggtttta tgaaaacaag tattgaatat ggtctaacac atccagaagt aggtgcacct
    30961 ttacgtgagt acatcctgtc tttaggtaaa acattagaag cagaaggaag caagatcgat
    31021 cataatccaa aaggaataac agaaatcaaa gaagaaaaga aaaaataacc cttttttcta
    31081 acgagcttca gctgctaatt gaataaaaag tagttgaagc tcgtttttat ttgtttaaaa
    31141 aacacgaaaa tgctatcctt atagaaaaga gagacaagaa gggagtttga tcatgtcagg
    31201 aggagaaatt gcaggattga tcgcagcaat cgcctttgcg atacttgtcg tttttatcgt
    31261 tcgtgtgttg ttgcaagttt ctaaaacttt agaaaaagta gatcagactg tagcagaagc
    31321 aaatacgacg atcgaaatcg tcacaaaaga cgtagatctt ttgtctagac aagtagaagg
    31381 cttactggtc aaaagtaatg aactgctctt ggatatcaat ggaaaagtcg caacgatcga
    31441 tccattgttc acagcagttg ctgatttaag tgaaagtgta tcagaactta atcattctag
    31501 taaaaacatc gcgacgaaag tcggcggaat cggtaaaacg acagctaaag cgacggttgc
    31561 cggaaaagtc ggtgggacag cgatgaaatt ttttaaaaac aaaaaacata ctgaaacgac
    31621 aggaggaaaa taaaaatggc taaaaaaggt ggatttttat taggtgcagt agtcggaggc
    31681 acagccgcag caatcgccgc gttattgtta gcaccaaaat ctggtaaaga acttcgggat
    31741 gaattagctg cccaagcgga tgatttgatg gatatggctt cagattacac agatatggcg
    31801 aaagaaaaat cgactgagtt aacaggtatt gcaaaagaaa aagcgcaaga tctttctcaa
    31861 caagcaggtg atctagcagg tagtgtcaaa caaaaagtaa gtgaatcagc agatgaagca
    31921 ggaagtgaat ctgacgatat cttgttaaat cttaaagaac aatcagctga cttatctaat
    31981 cgtttcaaaa aaacggcaga agatatgaaa aaacctgcag atgaattagg aagtattgct
    32041 aaagatactt cagaagatat catgattgat gtaaaagacg ctgctggtaa agcaggagat
    32101 actgtcaatg aaggaatgtc agaagcaaaa ccagttgcag atgactcaaa agaaatgatg
    32161 aaaatggcaa aagaagatgc gaaagaagct aaaaaagaaa taaaagatac aatgacagat
    32221 tcatctacaa atcactaaaa tcacaaattt atagaataaa aaggtgggag cggactagct
    32281 ctcacctttt ttactcttat ttttctaaaa caagtaattc ttttggtgta gtcgtgaatg
    32341 gcacacagcc atcgcttgtc acatatacac agtcttcgat acgtacccct actttttcag
    32401 gaatatagat tcctggttca agagagaagc acatcccttc ttcgattact aagtcatttc
    32461 cttctacaag ggaagggaat tcgtggacgg ttgttccgat cccgtgacct aaacggtgat
    32521 tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga tcaagttcac
    32581 ctgctgtcac acctggacgg acggcttctt gtgcggcaag ctgtgcttca agagtgatgt
    32641 tgtagatttt ttcttggaag tcggttggtt tttgataagc aattgtacga gtagcatcac
    32701 tgcaatagcc attccaaaca acgccaagat cgaataacac aagttcattc ggtgaaatct
    32761 tcgtatttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg actaatgtgt
    32821 cgaaagacat ttgtgaaaca ccttgttttt tcaattggta ttcaatttct gcaatgatcg
    32881 cttgttcagt cacgccttct ttcactgctt taaagccaat ctcaaatgca acatcggccc
    32941 atttaccagc ttcgatcagt ttgtcttttt cctctagagt tttgatcagt tgtagacgtt
    33001 ggatgatgga agttagatca gtgtaagaat ccgttcccgt caagatatca gagatagcat
    33061 cgaagcgctc gacagtcaag gcgttctttt caatccctac attgccaggc tgaccatagc
    33121 gagcacgaag ttcttttccg atgatctccc aagggttttc gctgtctaaa tagccacgga
    33181 catcatacgc ccaactactg ttttgagcat cttcaacttc caaagcagga gtgaaaagga
    33241 aaggatcttg ttcaagaggg ataaaaagag ctagtacacg ctcatgagga tcactttcgt
    33301 atccggaaaa gtaagcgatg tggccagggt cgctgatata agccaattcg acttggtgtt
    33361 gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa cctactttct
    33421 aaattaattt tgtattcaat aattgtacca ctgatttatt aaaagaccaa cgttctaaaa
    33481 actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat tcttgagatt
    33541 atttgatatt ctattttaga aatgtaagac gtattttcag aaaacatata aaatatgaat
    33601 aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag agaggcaaat
    33661 gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgttaa accagcaaca
    33721 agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaacgc agttgcgcgt
    33781 ggcttggcaa gtaagaaaac aacaacagtt ggtgtaatca tccctgatgt cagcaatatg
    33841 ttctttgctt ctttagcacg tggtatcgat gatgtggcaa caatgtacaa atacaatatt
    33901 atcttagcaa attcagatgg caacgaccaa aaagaagtca atgtattgaa taacttactg
    33961 gctaagcaag tggacggcgt gatcttcatg ggtcaccata tcacagacga aatccgtgga
    34021 gaattttcac gttcaaaaac tcctgttgta ttagctggct ctattgatcc agatgaacaa
    34081 gtaggtagcg taaacattga ttatgtatcc gcaacaaaag atgcagtaaa caaattggca
    34141 aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt tgatcgatcc catcaatgga
    34201 caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa ataacctacc atatagcgaa
    34261 ggattgatct ttgaagcaca atacaacttc aaagatggtc tatctctagt cgatcggatc
    34321 cataatagcg gtgcaacagc tgtctatgtt tcagatgatg aattagccat cggtattttg
    34381 gatggtttat tagaccgtgg cgtgaaagta ccggaagaat tcgaaatcat cacaagtaac
    34441 aattcactac tgacagaagt agctcgtcct cgtttaacaa gtatcacaca accattatac
    34501 gatttagggg cggtatctat gcgcctattg acgaaaatga tgaataaaga agaagtcgaa
    34561 gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatctacaaa ataataaaag
    34621 gacaaccatt cagaggttgt gtgcctgccg tttaactctg cgttacaagg agcaatttca
    34681 aaaaacagca tctcatgttt gatgaatatt gtgactcgtg attcggagtt ggcaggagaa
    34741 caccgtttat ttgggaaaag gggttatgac aaaattttgt tataatcctt tttttgtgtc
    34801 ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta tataaaacaa tccgtgtata
    34861 gatgctgcat tttgttcacc accatcaaaa aaataaggga ctgtgacaat actattgtca
    34921 caatccctta ttactgtgta ttctattaaa tcaatcatct ttctcatctg attctttagt
    34981 tgcttgattc gctcttgcat aagctgaagc ggtgttccag taatctgtat agttttcatc
    35041 ggtaccgcca acgccaaatt taaaggcgct tttcttcggt ccatttttcg cccatagcga
    35101 ttcaactgtt tttcctggtg tttggatgga ttttttattg acagtaactt ttccaggtgt
    35161 ttgaccagta aatccagata cttttttctt catcacatca gatgataatt cgaatttctc
    35221 atcagtgcca aaaatgtcag gttttgcttg gtaagcttga ttgatcagat tggcaagata
    35281 attagccgaa cgtatccttg ctttgctgtc cattccagta ttgtcatcgt gccctgccca
    35341 gctactgatg gtaatagacg gagtagagac aattagccat gaatctcggt attcattggt
    35401 agaaccagtt tttccgaccc aatctgcttt tcctagattt ccgtttaagc ttgagatggc
    35461 atctttgaat ggtgtagtga tttttgcatt gatcacacta cgcatcatgt cattcatgat
    35521 cgatgccgtt gcttccgaat agatccggac agagttgctt tcgtgtttat aaattacatt
    35581 tcctgcgtta tctgtgatgg aatcgatgat atagccttct tcatagacgc cgccgtttgc
    35641 taaagcctga aatccgttgg tctgttgaag cgtcgtgaca tctactgtac ctaaaggagc
    35701 agattcaacg ccccaattgt catttgccgg gtagttcatc tttgccaagt agtgctcgta
    35761 agcatattgt ttcgatccac cggaattcaa cacatcttga tataagtgat aagccgggat
    35821 attgttggac cattctagtg actcacggac ggtttggaag gtgttcgatc cttcgttagt
    35881 agcattgacg attttctcgc cagcattttc tccttcttgc caagttgttg cataatctga
    35941 tacacgggat tctgatccga taagccccat gtcgattgca ggtccataaa caagaactgg
    36001 tttgattgat gagccagctt gacgttctgt atcgaaggca tggttatttt gattctgact
    36061 gtaattccgt ccgccaacga atccgtagat gcggccagtt ctgttatcca tcaatacatt
    36121 tccggtttct acttgactgc cagcaccatc atctaacatg tatccataat tttcaacgcc
    36181 attttgcaat gcagcataga catctttatc gattgtcgaa tggattgtat atcctttatt
    36241 ttggatcgtt tgctgtgcct tttgataata agcgtcactg accgatgaat cagacatatc
    36301 agcgttgtct ttttcagcca attgttgtgc aatgattctt gttgcttcat tcatcacagt
    36361 ataatacaag aattctctgt cagtctgttc tgcgatttgt tgtggtagaa agtcttttgt
    36421 aaggtcatag gcttttgctt cttcgtattg ttctttcgta atttggcctt cacgatacat
    36481 actgaataaa acaaaatctt ttctggcaag gccggcagaa agatcttctt ttagcgcgcc
    36541 tgtgttcgtg tatggactat acgtgatcgg gctttggggt aatccagcga tataagcagc
    36601 ttgcggcagc gtcacatctt ttgcatctac accaaagatt ccttttgcag cttcctggac
    36661 tccagcaatg ttttgtccct tattattacg accaaatggt gagacattca aatacgtagc
    36721 aatgatctca tcttttgaaa agtatttttc tacttgtgca gaaagaatga tctcgtttgc
    36781 tttacgtttg aatgttgttt catctgtaag gatctgctgt ttgactaatt gctgtgtcaa
    36841 agttgatcca ccagaagagc caataccagt agcttcagat actaatgctc gtaaaacagc
    36901 tttaggaacg taaccttggt gtttatcgaa gtattcatcc tctgtgctga taattgcagt
    36961 tttcaataaa ggtgaaatct tatcagatga aatagtcgtg cgcatcagat ctgtctggat
    37021 ttttgatatc tctgtattat ctgcataaac aatctttgac gtttctgtaa tgtttcctag
    37081 ttctgtctgc agtgcttttt tagtcggcaa ttgtgtgtct tcgacgagat aggcaaaata
    37141 gccagcgcct attccaatac ctagagctgc gaacatcaaa agaagaacag taataaaaac
    37201 agtcaatgat tgaaaaactc taaaaataat cttaggaaca aaccattttt ctttttttct
    37261 tctattctgt ttttttcgag tatttttgcg tggcaaaagg gtcacctcaa ctaatggttt
    37321 tatttcgcta attatagcaa ataatagaac aaaaaaacag acaaggctgt ttttggcagg
    37381 aatttctttt ttaaaagagt taaaacgtga gaaaatgatc tttattataa aagagttctt
    37441 aagcttttct ttagagaaaa tttcagttac tatggagaac agggcaaaga aaaatcaatc
    37501 attttctttg tatatcatct taccaatata taggaattgt tagtaacaat tgcctttcaa
    37561 ggaggaatcc atccatgtta ttaggctcac acgtcagcat gagcggaaag aaaatgctgt
    37621 taggagcagc agcagaagca gccagttatg gatcttcgac ttttatgatc tatacaggcg
    37681 cccctcaaaa cactagaaga aaagccatcg aagagatgaa tattgatgcc ggaaaagcgt
    37741 acatggcaga aaacggtcta acaaatatcg tcgttcatgc cccttatatc attaatttgg
    37801 ggaatacgat caaaccagaa atgtttcctt ttgccgtcca atttctgaga gaagagattg
    37861 ttcgtgcgga agctttaggc gctactcaaa ttacacttca cccaggtgct catgtagggg
    37921 caggaacaga agccggaatt gctagaatta ttgaaggctt gaatgaagtt ttgacaaaag
    37981 aacagacggc acaaatcgct ttggagacaa tggcaggtaa aggtacggaa atcggtcgaa
    38041 catttgagga attagcgcaa atcatcgatg gagtaaaatt aaatgaaaaa ttatccgtta
    38101 cttttgacac ctgtcatacg aatgatgccg gttataatat taaagaagac ttttcaggtg
    38161 taatggaaga gtttgataag atcatcgggt tagatcggct taaagtactc catatcaatg
    38221 attctaaaaa tccgcaaggt tcgcataaag accggcacgc caatattggt tttggaacaa
    38281 tcggattcga cacgctgaat aagatcgtcc atgatccaat gtttgacaat atttcgaaaa
    38341 tcttggaaac tccctatgtc ggcaaagata aaaagaaagc ttacgcacca tatggaaaag
    38401 aaatcgccat gttcaaagca caaatattcg atccagaagt gtttcctgag ttattagcag
    38461 aagaagtgat actctaagat tttctatctg acagcagcaa aaaaggacca ggcacattgc
    38521 cttgtccttt tttgtttaag aaacaaagga gtactttttg cagtcttttt catcatgcat
    38581 cttctccccc ctctttttaa atttagacaa acaaggtata ctgttagaaa agtaaaaaaa
    38641 cgaaaagttt cacaagcaag tggcaaaacg tgattggaag gacgaaaaga tgctgaacac
    38701 tttaaaaccc ttgatcaacc aactaaaaaa gaaacataca tactttattc ttggcatagc
    38761 cctattattt acaattattc gtttgtattt atatagtaaa gcaatctatg gaacagacat
    38821 gtcggcaacc tatgatgacc agctgctgat tcgctatgct caaaatattt tggacggtaa
    38881 atggctaggg gagtatacga ctacaacact ttccaaagga atctcctaca gcttattttt
    38941 agtacttgca cataaactgc atctttctta tgctgttttg ttcggcatgt tcagtatttt
    39001 tgccagtata ttggttgcac tcgcgtttaa accgatcgtg aagaacaagt atcttctttt
    39061 aagtatctat ttttattttt tgttttctcc gattagtttt acacatgaat attccactcg
    39121 aacatatcgt aatgccctcg tgattccggc tgttgagatc attatcgctt gtttactagc
    39181 tatttattac cgcaaatacg gttctagcag aaaattgctg ccatggtttt tagggctttc
    39241 tgtcgctttt cctttctttt ggttcattcg cgaagattct atctggcttc ttccttttac
    39301 tgtagtagct ttgggtatca gtttcgtcca gatcttgcta gggcaagact tttctttcaa
    39361 agaagtaaag aagttaaaaa aacgactctt tcttctctcg aaacgggaat ggctgaaact
    39421 ttcattgttt ttacttccta tagttggctt ttccatcgtc tatcagtgga tcgaatataa
    39481 aaatgagaca acatacggta ttgcaaccat caatgaccgt tccagtggag aatttggacg
    39541 tttgatgaaa caactgatcc gaatagatga tgaaacgaac ttgaataaag aaaacagtga
    39601 gatatgggtc tcacatgctg cactaaataa agcattagcc gcatctccta cattccatac
    39661 tgtttctacc cgtattgacg aattatatac gactcacgcg tggactcaag gtggaaaagt
    39721 aaaagaatta cccggagata tcatcttttg ggcattgcga gatgtggtaa gcgaatctgg
    39781 ttattaccaa aacaatgcaa aagaaaccaa tgatttttgg aaaaaagtca accaagaatt
    39841 agaagaagcc tatcacaagg gaaccatcaa aaagaaaaaa gagttctatc tgatgggatc
    39901 aggagatgga aagacgatga gtgatctgcc aatcgtattc gatttccttc aatcaggata
    39961 cgcttatgca tggcgatata aagatttcca tcaaggagga aattatagtt tcggaacgca
    40021 agaacaagtc aaacaggctc aagaattatt aaaccttccg ctaatggaga attggatcga
    40081 tagtaatgaa ccgagaacac ctaatttcca attaacaaaa tcagcaaaag tcgcgaatgt
    40141 catcataaaa atttaccaag ttctggctat tcccgtgctg attgcttcaa tagcagggat
    40201 attacttatg atactaggaa ccgtatttgc aaaagctgat cgtgcctatt atagttcctc
    40261 tttgattgtg gtcaccggat taatactgac acaattggtt tttcttttcg gtgtctcgtg
    40321 gttttgttct tatgcgccag aaaaaaagga ttatttttta agtgtctaca ctggcgcagg
    40381 cgtgccatta acgcaattca tcgtagtaac aagcatgcta gttttcagta aattaaatct
    40441 gaaaaaggct ttatcttcta aataaaaaga cccttggtag ctagattttt aacctaacta
    40501 tcaagggtct ttgtgtggaa aaatcagttt ctattcgatt tcttctaccg tttcctgcaa
    40561 acgctgttca tattttttgt ttcctttata taaatcacca atcgtccatg ccaacaggag
    40621 aaggacaaga acaatgatta cataagcgat gtgatcagcc aatgctagtt gagcagaagt
    40681 ggcttgttca ccaaagaaac tttcgatctg tcctggtaat cctcgtaagt tcaagtaagt
    40741 tagactaatc acagagaacc agccaagaag ttttacgatg aatgaatttt taaatcggct
    40801 acccatctcc gcttggctgt tggtcatcat cagtaaaggg atcatcgaaa acggcaacgc
    40861 aaaagccaag aacacctggg attcattcat caagttattc aaagcggtat gttcttcgat
    40921 cgttcctttt gtacttgtaa acaaaacaca aatcaataca ggaatcacag aaagcaatcg
    40981 tgtgaccagt cttcttagcc aaatcgggat acgcatatgg atgaagcctt ccatgatgac
    41041 ttgaccggtc aacgtaccag taatagtaga gttctggcca gaagcaagaa gtgctacagc
    41101 aaataaagtg gataagatac cagattttgc tacagcaatc aagataccat tgctcatagc
    41161 tgatggatca gataaggctt catacagacc aaaaaaggaa ggatcttgga cagaaccggt
    41221 tttgaagaca gcgacaccca tgatcaatag cagtgcattg actagaaaag ccatcgacaa
    41281 ttggatatta gagtcccaag tagaaaaacg tacagcttgt gctacatctt cttcgtcttg
    41341 gtgatcaatc ttccgagttt gagaaactgc tgaatgaaga tataagttat gcggcatgac
    41401 tgttgcacca ataatcccta aagctccagt cagcggagtt tcgccgccga tgaccggtga
    41461 gtctgagaat gtatgactgt tagggataaa gccagcaaat aaactgtgcc aatctgggtt
    41521 agacaagcca acttgataga caaaaacgaa taaaatgacg aaaattaagc agacaaccag
    41581 tgcttcgatc ttacgaaacc cgacttttgt cagtagtaag agaacgaaaa catctaatac
    41641 agtaataaag acggcaatca ccaatggaat atcaaaaagt aagtagaggg cgattgctgc
    41701 accaatgact tctgcgatgt ctgttgccat aatggctaat tcagtcaaga tccataaaat
    41761 gacacccaat gtcttacttg tgcgtgctcg gattgcttgg gccaaatcca tttgggtcac
    41821 gattcctaat tttgctgcca tatactgtaa aagcatagca atcagactag acatcaaaat
    41881 aactgacatc aataaatatt ggaaattttg tccaccagtg atcgaagtgg accagttacc
    41941 tggatccata taaccaactg ctactaatgc acctggtcca gagtaagcaa gaagtgtttt
    42001 aaaaaaactt ttcccctttg gtacatcaac tgttccattt acttcagcta aagataaacc
    42061 atttgtatgt tcaataagtc gatgcttatg aaattgtttg ttggattgat tattcaagaa
    42121 aaaaccacct ttcctattta tctacgatta cattctacac ctcaaaaaga aaaaattaaa
    42181 gaaaaatatt cggtatgcct aatttatttt cgtggcgcgt cttgttagat gacgaaagaa
    42241 attttgttct cctctaaaaa aaccactatt ttttgcatga aactaaagaa tacgcctttc
    42301 ttttttcaat aaactttagt aaaataagtc attgagagca attcggaaat agaaaggaga
    42361 gatttatatg ttatcaacag gtattgtcgt acttattgct attattgctt tgctaatcgg
    42421 cgcagtaggt ggctttttcc tagcgcgtaa atatatgaaa gactatttag aaaaaaatcc
    42481 tcccgttaat gaggacatgt tgcgatcaat gatgatgtca atgggacaaa aaccatctga
    42541 gaagaaaatt cgccagatga tgcagcaaat gaagaaccaa gggaaaaaat aggttctgac
    42601 ccaacgactt tttacgggct gattttttca gtccgttttt tattttgtaa tttgttagac
    42661 tattcagatt attcagcaaa aagacaagca cagacaatcc taggctcttg ataaagacaa
    42721 aggaggagta aaatgtcgat ttttagaaag ttaggctggt tttttcgtca ggaaaagaaa
    42781 cattatttaa ttggggtttt ctcgctattc gcagtggcct tggtacagtt agttcctcca
    42841 aaagtgattg ggatcatcat tgatgagatt gccgataaaa atttatcagt aaagatcatt
    42901 ttcgggtgga tcttcctatt gattatcgct gctttcttac aatatctttt tcgttatatc
    42961 tggcggacga atatttgggg aagtgcagct cggttggaga aagaacttcg gcagcagtta
    43021 ttcaaacatt ttacaaaaat ggacaatctc ttttaccaaa aatatcggac tggggatttg
    43081 atggctcatg caacgaatga tttgaatgcg atccagaatg tagcaggagc tggtatcttg
    43141 acctttgcag attcagtgat tacgggcgga acaacgatca ttgtgatgat tttgtttatt
    43201 gattggcgct taacactgat tgcgctgatt cctctgcctt tgctggccgt cacttcacga
    43261 gtgctggggt cgaaactcca tgatgctttt cgtgattcgc aagaagcttt ttctagtatc
    43321 aatgataaga cacaagaaag tatcactggg atcaaagtca ttaaaacatt tggacaagaa
    43381 aaagaagatc tagcggattt tgaagaaaag attgaagatg caattattaa aaacaaacga
    43441 gtcaattttc tagactcctt atttgatcca ttcattacct tgattatcgg tctgtcttat
    43501 gttgcaacaa ttattttagg tggaaagtat gtcttggaag gcacgatctc gatcgggcag
    43561 atggtctcat ttattagtta tatcggtatg cttgtttggc cgatgtttgc gattggtcga
    43621 ttgttcaacg tattggaaag aggaaatgct tcttatgatc gcgtcaatga acttttgcat
    43681 gaaaaaacgc atatcgtgga acaactgggt gcagtgcaga ccccggtaaa aggcgagctg
    43741 aatgtagcta tttcctcttt taattatccg aaagaagaat caccagcatt agaacaaatc
    43801 aagtttgcaa tccaagaagg agaaacatta ggtattgttg ggaaaactgg tgcgggaaaa
    43861 acaacgatca tcaaattact gatgcgtgaa tacgatgatt atcaagggaa aatccaattt
    43921 ggcggacgtt cgatcaaaga atattcattg aatgctttat taggatcaat cggctatgtg
    43981 cctcaggatc acttcttgtt ttcgatgacc attcgagata atatccgttt ttctaatcca
    44041 aaactttcag aagaagaagt agagcatgcg gcttctttag catttatcaa caatgaaatc
    44101 aaggaattac caaaaggtta tgatacctta gttggagaac gtggagtctc tttatctggc
    44161 ggacagaaac aaaggatttc gattgctcga gcattgatca aaaatcctga attattaata
    44221 ttagatgatg cactttctgc agtagatgcc aaaacagaag aagctatctt gcataattta
    44281 aaagaaataa gaaaagagaa aacaactatc attgcagctc accgtttaag tagcgtgatg
    44341 catgcaaaag aaatcattgt tgtcgatcaa gggaaaatca ttgaacgagg aacccatcat
    44401 gagctgcttg cactaggcgg ctggtatgaa caaatgtggg agaaacagca attagaagcg
    44461 aagatagaag gaggcgaggc ctgatggatg aaaattatca atcggaatgg acaaaatcga
    44521 ttccacttaa agaacagaaa aagatcatca aacgactgat gaagttcgcc aaacctttta
    44581 gaacaacgtt catcgttgct atcttatttg cgtttgctct gtctgtgatc aatgtcctat
    44641 tgccaaggat catccaaact tttatggatg atcatctggc taaacagtcg gctacgacac
    44701 aagttatttt gttttttgct ggtatgtact tatttggagt cctagtaaaa agtatcattt
    44761 ggtttttcca atggtatttg tattccatgg cttcattgaa gacctatcag tatattaggg
    44821 taaaattatt tgaaaagctg catacactag gtatgcgtta ttttgatcag acaccggcag
    44881 gatcaaccgt ttctcgagtg acgaatgaca cagaaacgct atttgaattt tggtacgtct
    44941 ttttgatggt attgactggg atctttgcag tcgtttcttc attcattgcc atgtttcaaa
    45001 tcaatggaga aattgccttg tggactttgg tgttcttgcc gattttagga attgtcatct
    45061 ggtattacca gaaatttagt tctcgtattt accgaaatat gcgggaaaaa ttaagtcagc
    45121 tgaatacaaa attgaatgaa tcgatttccg gcatgcgtat tatccagcag tttcgccaag
    45181 aagctcgttt agctaaagaa tttgaacaag tgaacaatga gtatttagac acgcgctatg
    45241 cgatgatcaa aacgaattcg attctgttaa gtccgatcat caattttcta tatgcattgg
    45301 cgattgcgtt ggcgttgact ttatttggga tcgatgcgtt gcattctccc gtagaagttg
    45361 gactgatcta tgcatttacg acttatgtcc agggattttt taatccaatg tctcaaatga
    45421 tggacttttt gagcatcttc acagatggga tggttgctgg tagtcgtatc ttgaagatta
    45481 tggatacgga agaatatgca ccacaacaaa accctggagc agatcaaatg attacttcag
    45541 gtaagattga gtttcgcaat gtaagctttt cttatgatgg agagcacaat gtattaaaca
    45601 atatctcttt tgttgctaat ccgggagaaa ccgttgcatt agtgggacac accggaagtg
    45661 ggaaaagctc gatcatcaat gtgttgatgc ggttttacga attttatgaa ggtcagatat
    45721 tgattgatga tcatgacatt cgagaatatc caatggaaga gttacgtaag aaaatggggc
    45781 tggtcttgca agatgctttc ttgttttatg gggatatcgc aggaaatatt cggatgatga
    45841 atccagctat cacagacgaa cagatacgcc atgcggctga gtttgttcaa gcaaacaaat
    45901 tcatcgatga attaccaaaa ggatatcact caaaagtgat cgaacatggt gccagctatt
    45961 ctagtggaca acgacagctg atcacttttg cgcgaacaat cgtgactgat cctaaaattc
    46021 tagtattgga tgaagcaaca gcaaatatcg atactgaaac agaaggattg atccaagaag
    46081 gattggcgaa aatgcgacaa ggacggacaa cgattgcgat tgcccatcgg ctgtcaacga
    46141 ttcgagatgc agaattgatt ttagttttag acaaaggtca tatagtagaa cgcgggaatc
    46201 atgaaacact tctagcgcaa aatggtttgt atgcagatat gtacaaactg caaagtagtg
    46261 gtatataaaa gatgttgtga cagtagcatt ttgacctaag cactagagtg aaaataaaac
    46321 atagcttccc atatttttca tctgtgagag ttagtgtcgt agttaccaga tttaaaaaag
    46381 acgacgtcag ctagtcagaa gtgcctaata gcccctaaga aagcgttgac aaaatcgttt
    46441 gctttcgata atataaagaa aacgatacaa cttggatagt gattgcctga tgcaagctaa
    46501 acctgatgag tctcccatgg tttcatggac ggctttttgg gtttttcttt ttgttttgga
    46561 tacagcccta tatatcatgg aaaggagcaa aacatgctga ttgagaaagt actgaataac
    46621 aacgtcgtaa taacaaggga tgaaagagat cgggaaatga ttgtgatggg aaaaggattg
    46681 gcattcaaaa agaaggtggg tgacccgatt cttgactcat gcatcgacaa aaaatttcag
    46741 ttgacaaatg acggactttc acaacagttc caagaattgg cacaagcgat tcctcttgag
    46801 tacttagaaa tttcttgtga aatcattgaa tatacaaaag aggctctgca agtccattta
    46861 aatgattctg tgtatatttc attgacggat cacttgtata cagctatcga acgtcaaaaa
    46921 atggggatct ttgtgccaaa tgtattgctg tatgatatca aacaactgtt tcctaaagag
    46981 tatgccattg ggaaaaaaac agtgaagaaa atctcggata aataccacat caagttatca
    47041 gaagacgaag ccggatttat cgcattgcat ttagtcaatg cacaaggcat tcaaagccag
    47101 caagacaata cctacctgtt taccacaaca atacaggata ttttaaatat cgtccgctat
    47161 tactataaga ttacatttga tgaagattca gtccactttt ttcgattcgt cacacacctg
    47221 cgtttttttc tgacacgtgt cctagatgga gcgaaatcag aagatggaga agtttctgag
    47281 gaattgttcc aagttattca aaaaaaatat aaggatacgt ttggttgcgt tgagaaaata
    47341 gcagactttt taaccggggc tttcgactac cagatgtcca cggatgaaaa aatgtattta
    47401 acgatccata ctgcgcgttt agtgcatgag aatcgttgta aataaataaa aaaggaggac
    47461 aaattaacaa gaacgtatga aataagggta gtgacattca gttggctaaa ccttccacta
    47521 attaattgga gggaatagaa atgggaaaat accaggaatt agcagaaaac atcgtaaaga
    47581 atatcggagg aaaagaaaat atccgtagct tgacacactg tgtgacgcga cttcgtttca
    47641 aactaaagga ggaaaataaa gcaaaggatg atgttttgaa aaagatggaa gggatagtca
    47701 ccatcatgaa aagcggcggg caatatcaag ttgtaatcgg gaatcatgtg ccagatgtct
    47761 atgcagaagt actgacagta gccgggattt ccgatgaagc agaagaagag gtttcttcaa
    47821 gtagtaatct gttcaatcga ttaatcgaca tattaagtgg ctgtttccag ccttttttag
    47881 gtgctttggc tgcagcggga atggtcaaag gattaaatgc tttgttcttg tttctcaaat
    47941 tttatactga aggatcgggt acgtacatca tgctgaatgg gataggggat gcaatttttt
    48001 atttcatgcc agtgatctta gggtacacag cagcgaaaaa atttcatctg aatccgatgg
    48061 tggggctcgt gattggtgca gcactttgtt atccgactgt acaaggagca gcactacaaa
    48121 gtggtttccc tgatggcagt cctgcgcctt atagcttgct gggtcttccg gcttatgaaa
    48181 catttttggg tatcccatgg gtgggcagca gttatactag tagcgtcgta cctgttatct
    48241 tcattatcgc atttgccgga caagtccaaa aaattgccaa gaaatggatt cctgcagtcg
    48301 tccagacctt tttggtttct ttttctgtgt tattaatcgc acttcctgct ggctttttga
    48361 ttatcggtcc gattgtcagt atactgacag atctattaag cacgggattc caagcattga
    48421 tggacttttc tccagctgtg tatggtgcag ttctagggtt tctttggcaa gtactggtga
    48481 ttttcggact tcattggagt attatccctc ttgcgattat gcagctagcg caaaatgggt
    48541 ggagtcagat gttagtaggc gtttatggcg cgagttttgc acagacagca gtggtattgg
    48601 cgatgtattt caagttcaag gatcaaaaaa tgaaggcgct ttgcatgcca gctgtgattt
    48661 caggaatctt cggcgtaaca gaaccggcta tttatggaat caccttaccg aagaagaagc
    48721 catttattta ctcgatgatt ggtggtgctg tttcaggaat ctatttgatg gcatctggaa
    48781 caatcagcta cataatgggc ggattaggga tttttggggt ggtaaactac atcacggaaa
    48841 cagacgccag tggtatgttt caagcgttta tcggcattgc tattgcttcg gtaatcgggt
    48901 tttcgctgac ttttttcttt tggaaggatg aagcaggtga aacagatgct atacagaaaa
    48961 aatcaggtaa agaaattgta aaaacaccga tacaaggaca aatcgctcca ctaaatgcag
    49021 cgaaggatgc agcttttgca caaggaacac taggtcgagg aatcttaatc taccctgaaa
    49081 aaggagaagt acgtgcccct tttgacggaa cagttatgac cctgttcccg acgaaacatg
    49141 caatcggaat ggtttctgaa acagggctgg aattgctgat tcatgtcgga ttggatactg
    49201 tgcagttgga agggaaatat tttgaaagct tagtgcagca aggagaaaga gtgagacaag
    49261 gcgatctgtt gctacgcttc gacaaaaaga aaatcgaaaa ggaaggatac agtttagaaa
    49321 cacctgtgat cgtcaccaat tacacggatt atttggatat tttggaaaac caaggggaga
    49381 cggtcgggcc agacgatgca cttatcaccg cactgacctg aacggttagg tgaagaatgg
    49441 actaggctta actattcttt ttattccact tctttatttt caaaattgaa aggctctttc
    49501 atgatggctg agctgatagg gcgtttatcg aatttttgac cgacagaaat tagatggact
    49561 aaattctgtt gataattttc tgcaaaaaca caactatata acacgtctag aagataacaa
    49621 attgatgtat tgatcgtaaa attaccaatt tttgaataca gtcgctcgcg tgtcgtaagt
    49681 cgcaaagcgg ctgtactcat tgcagatagc gttgaatcac cgatactggt caaagctaaa
    49741 attggaacat cattttgttt caatatttct gcggtacgaa ggatcacatt gttttcaccc
    49801 gtataagaaa tcagaatccc gcacatatcg ctcgtacaat tgtacgcttc atagaatgat
    49861 tcaccaaaag tggtgacaat tgtgacatcc attttgatgc gcttcatttt cagcatgaaa
    49921 tcttgagaaa tcaaagtatt cgagttactg gcgaagatca cgattttttt tgcctggagc
    49981 agtaaatatt tagctttttg cagttggtca tgatgaatga gagaaagtgt atcatgaatc
    50041 gtcatctgtt ctaaagaagc cattttattt gcgattgtca taataccgtc tgtggtggaa
    50101 aaaggaagat tcgcatctac gtcttgaaaa ttcccttcaa gataggctgt ttcagctaaa
    50161 aaagcattac gaaaactgac ccagccatca aaacccattt tttttgctac acggatgagt
    50221 gtagacgggt ggacataaca tcgctcagct atcgcttgga tggtcatttc gccaagtgct
    50281 ggagaatcgc ttaagagaaa ctggatcact tcattttctg aaggagaaaa ggagatttct
    50341 ttgatttttt cacgtaataa catgtagata ccttcttctt atttttttac gtaaattata
    50401 acttttttga aaatgttttg taaacggatt tatactatat aacttaaaat aggctttttt
    50461 tgacaagata tttacaaaaa tccactagaa aacagtaact tttgtaaatg ttactggaaa
    50521 gaaacggatt tctattgttt gttttgttta caaaaaagat aatgaaagtg taaaaaagta
    50581 aaggagtgag aacatggcaa aaggaatcaa aatcgctacg attggtggag gcagcagtta
    50641 cacccctgag ttgatggaag gatttatcaa aagatatgag gaattaccga tacgagaaat
    50701 ctggctcgta gatgtagaag aaggaaaaga aaagcttgag atcgttagtc agatgtctca
    50761 gcgtatgtgg gatgcttctc catatgaagt caagatctat gcaactctgg atcgggaaga
    50821 agcattgaaa gatgcggatt ttgttacgac tcagtttcgt gtcggtcaat tagatgcacg
    50881 aatcaaagac gagcggatcc ctagttatta tgggatgatt gggcaagaaa caaatggtgc
    50941 tggcgggata ttcaaagctt ttcgtaccgt tccagtcgtt ttggcaatcg ttgaggacat
    51001 gaagcgttta tgtccaaatg cttggctgat caatttcgcg aacccaagtg ggatggtgac
    51061 agaagcagtt atcagatatg gcaaatggga taaagtgatt ggattatgca atgtgccagt
    51121 gatggcgatg atgacagaac cagcaatgct tggcaagaaa aaagaagagc tgatctacaa
    51181 gtttgccggt ctaaatcatt tccattggca caaagtagca gataataaag gaaatgaccg
    51241 cacggcagaa ttgattgatc gtttatacga tgaagataat ggattaccga aaaatatctt
    51301 tgatatcccg tttttcaaag aacaattaaa acaaatgaac atgatccctt gtggctacca
    51361 ccgctattac tatcgtgaag aagaaatgct ggaacatgct ttagaagaat atcaaacgat
    51421 tggtacaaga gcgcagcaag tgaaagaaac agaagcagag ctatttgaat tatacaaaga
    51481 tccagaatta gaccataaac ctgaacaatt gcaaaaacga ggtggcgctt attattcaga
    51541 cgctgcctgt gaaacgattg cttcaatcta tggaaataaa gaaacacaga tcgttgtatc
    51601 tacaaagaat gatggagctg ttcctgacct gtcggcagat tgtgttgtag aagtcactgc
    51661 ctatgttggc gcacaaggag cgagaaatgt agcgtttggt tctcttcctg ctgctgaaag
    51721 aggctggttg caagtaatga agaatatgga attgctgacg atcgaagcag ctgtgactgg
    51781 tgattatggg acagctttac aggcgtttac gatcaatcca cttatacgat caggaaagac
    51841 agcaaaacgg atcatggatg agttgtttat tgcacaccag cagtatttac cgcaattcaa
    51901 ggaaacaatc agccgattaa aagaagaagg aatcgaagtt caagatgaac tggcaagaga
    51961 attatcaggt aatacacata taatggagga agtataatgg ggttcagaaa agatttttta
    52021 tggggcggtg ctacagcagc caatcaatgt gagggcgctt atgatgaagg tggacgcgga
    52081 ctagcaaacg tagatgttgt gccaatcgga aaagaccgtt ttcctgttat caccggaaag
    52141 aaaaaaatgt ttgaatttga tgaggatcat ttttatccag caaaaattgc aatcgatatg
    52201 tatcatcgtt ataaagaaga tattgctttg tttgcagaaa tggggttcaa gacttatcga
    52261 atgtctatcg cctggagtcg tatttttcca atgggggatg agaaagagcc gaatgaagct
    52321 ggcttgaaat tttatgagga tgtctttaaa gaatgccaaa agcacggaat tgagccactt
    52381 gtgacgatta cgcattttga ttgtccaatg catttgatca aagaatatgg tgcgtggcgt
    52441 tccagagaac tcgttggttt ttatgaaaat ctgtgtcgag tcatcttcaa tcgctataaa
    52501 ggacttgtca aatattggct gacattcaat gagatcaata tgatccttca tgcaccattt
    52561 atgggcgcag ggctgtattt tgaagaagga gaaaatgaag aacaaatcaa atatcaagcg
    52621 gcacatcatg agttggttgc aagtgccatc gcaacgaaga ttgctcatga agtagatccg
    52681 gagaacaaag taggctgtat gctggcagca ggagcatatt atccatacac ttgcaatcct
    52741 gaagatgttt gggcttctag aaaatcagat cgagaaaatt atttcttcat tgatgtccag
    52801 tcacgaggag aatatcccgc ttatgcattg aaagaaatgg agcgaaatgg cattcagatc
    52861 gaaatggaac caggggatgc cgcattgctg aaagaacata ctgttgattt tatctctttt
    52921 tcttattatt cttcacgagt ttcgactacc gacaacgaac tcttggaaca gactgcagga
    52981 aatatctttg cttctgtcaa aaatccatat ctgcaagcaa gtgaatgggg gtggcaaatt
    53041 gatccattag gcttgagaat aacgatgaat gatatttatg atcgttatca aaaaccatta
    53101 tttattgtag aaaacggctt aggtgcagtc gatacgccag atgaaaatgg ttatgtggaa
    53161 gatgattacc gaatcgatta cctggcagcg catatccagg cgatgaagga tgcagtagaa
    53221 ctagacggag tcgatctatt aggctatacg acttggggat gtatcgattt agtatcagct
    53281 ggtaccggtg agatgaagaa aaggtacgga ttcatttatg tcgatcgtga taaccaagga
    53341 aatggcacat tagcccgttc aaagaaaaaa tcattcaact ggtataaaaa agtaattgat
    53401 tcaaatggag aaaatctttc gaacaattga tcaatgattt ataaaagtct attgtttttc
    53461 agcggatttt tcgagtataa taaagctatt cgagaaacgc aagcagaaca atagactttt
    53521 tttcgcattg gctgtaaagt atgcttactt gattaagtaa aggagaatct acatatgtat
    53581 gatgtaatcg ttattggcgc aggtcctgct gggatgactg ctgctttgta tgcttcacgt
    53641 tcaaacttat ccgtattgat gatcgaacaa ggtgcccctg gcggccaaat gaacaatacg
    53701 gcagaaatcg aaaattatcc tggattcgat tcgatcatgg gccccgatct agcttataag
    53761 atgtatgaaa gtgtctcaag atttgggaca gaaaatgctt atggaatcgt tcaagatatc
    53821 aaggatcacg gcagccataa agaagtcatc tgtgaagata aaagttacga aggaaaaaca
    53881 gtcattatcg caacaggctg tatccaccgt aaattaggcg tacctggcga ggaagaattt
    53941 gctggacgag gcgtttctta ctgtgcagtc tgtgatggtg cgtttttccg taacaaacgt
    54001 ctagtagtca tcgggggtgg ggactcagca gtagaagaag ccatctattt gacacaattt
    54061 gcttctgaag tagtgatcgt ccaccgtaga gatgaattac gtgcacaaaa gatcatccaa
    54121 gaccgtgcat ttgcaaatga aaaaatttcc tttatgtggg atacagtcgt tgacgaaatc
    54181 gttggaaacg aaatggtagt gacaggtgtg aaagcacgta atgtcaaaac cggcaatgaa
    54241 tttgatttag cagcagacgg agtattcatc tatgttggac tggatccatt aactgcacct
    54301 tttagagaag caggtttgac gaacgaagct ggctggattc caacagacaa cgaaatgaaa
    54361 acgaatatgc caggcgtttt tgccatcgga gatgttcgtg aaaaagattt gcgacaaatc
    54421 actacagctg ttggtgacgg cggtattgct ggacaacaag tgtataaata cttggagtct
    54481 ttagaagaaa caacagcata agtttaaaaa gagtgaaaga acggtttcaa ttgttctttt
    54541 actctttttt ttcgcgtgaa atccactgaa tccgatttat gtgaatactt gcaatcatgc
    54601 ttgataaaag aatcctttct tgatttaagc gttttttggt cctcatactt tcatatctaa
    54661 taagtgaatg ctatacttat taagaaccat atttcagaaa gaggtgttat tttcatgtct
    54721 tgggaacaag tgtatgaaca atgggtacat gaagaaaatt tagaagaaaa cttaaaaaaa
    54781 caattaaatg atctgggtga agatcctgaa aaacttgaag atgcttttta tgcaccgttg
    54841 gaattcggta ctgcaggcat gcggggaatc ttaggacctg ggatcaatcg aatgaacatc
    54901 tatacggtaa gacaagcaac agaaggacta gcacgtttca tggatacaca aggtgaagaa
    54961 acaaaacgcc gaggtgtcgc tatcgcttat gactcacgcc atcagtcacc agaatttgca
    55021 atggaagcag ccaaaacact ggcacatcac aatatcccgt cttatgtatt cgaaagtctg
    55081 cgtccaacac cagagctttc ttttgcagtt cgtcatttga agacgtttgc gggaatcatg
    55141 gtaaccgcat ctcacaaccc agcggcttac aatggatata aagtctacgg agaagatggc
    55201 ggacaaatgc ctcctgcaga cgcagatgca ttgacgaaat atgtccgtga agtcagcaat
    55261 ccgctaaaag tcgaagtatt atctgacgaa gaagctaaac atagcgggtt gatcacgatc
    55321 atcggagaag aagtggacgc tgcttatcta gaagaaatca aagcagtgac gattgatcgt
    55381 gaattggttg aaacaatggg gaaagatttg aaacttgtgt acacgccact tcatggaaca
    55441 gggaaaatgt tgggcgaacg tgcgttgaaa caagctggat tcgaacaatt cgtactagtt
    55501 cccgaacaag ctgtggcaga tccagatttc actacggtca aatcgccaaa tccagaagaa
    55561 cattcagctt ttgaatatgc tatacgactt ggagaaaaag agggagctga cttgctgatt
    55621 gcaacagatc ctgatgcaga ccgtttaggc gcagcggttc gtttgccaga tggttcttat
    55681 gaagtattga ctgggaacca aatcggagca ttgtttgctc aatatatttt ggaagcacat
    55741 caatcaagag gcactttacc agaaaacgca gcggtattga aatcaatcgt ttccagcgaa
    55801 ttgcctacag caattgcgga acactacggt gctactatgt tcaatgtgtt gacagggttt
    55861 aaattcattg ctgaaaaaat ccaacaattt gaagaagacc attcacatac ttttatgttt
    55921 ggattcgaag aaagttatgg ttatttagtt aaaccttttg ttcgcgataa agacgcgatc
    55981 caagcattgc ttttattagc agaagtagca gcttactata aaaaacaagg caaaacgttg
    56041 tatgacggct tgcaaacgat ttttgaaacc tatggctatt tcgcagaaaa aacgatttct
    56101 gtgacaatga gcggacaaga aggttctgcg aaaatctctg ctttgatgga aaaattccgt
    56161 aaagaagcac cgacagaatt tgccggagca aaagttattc aaacagaaga ctttaaagaa
    56221 ttgacgagaa cagaccgtga aggaaacgta gaaaaactaa caacaccgcc atccgacgta
    56281 ttgaagtata cattggaaga aaatggctgg atcgctatcc gcccttcagg aactgagccg
    56341 aaaatcaagt tttatattgg tgtaaaagga agctctacag aagacgcagc cgaaaaagta
    56401 gcctcttatg aagcgattat caaaaagatg acagaagaat aaaaaacttg agactgatgg
    56461 aaaaagtggt aaactttaga agtcagtctt ttttcaagtt ggaggtgaat ggattgccag
    56521 acacgcaaaa atcaaaagta gagaaagtca gtcaattatt caaaatgttg agtgacccca
    56581 ctcgtcttaa aattctgcta tatctgaaag acggggaaca aaatgtgaca gcaatcaccc
    56641 aagcagtgga aatggagcag tctgctgtat cgcatcaact acgtttatta agagaaaatc
    56701 atgtcgtcaa gtctcatcgc gagggaaaag cgattttgta tagtcttgat gattctcatg
    56761 tactggatat tttgaaccag acactcaaac atgtggaaca tcaataacga taggtgcaaa
    56821 tagataaaca ctggagtgtg acaacgaaat ttcttcgttg tcacactcca gtgtttttta
    56881 agaaaaagac aaaaatgatt aatcgctttt ttctgttgtt tcagttccat aataactatg
    56941 atcttctagg tctaaagcat tcaaaataag cgaagccgtt tcttcaatag ataaagatgc
    57001 cacattgatc actacacatc ctagtttttc ataaagatca ttcgcaaaat caagttcagc
    57061 tctaattttt tcgatatcgg aataagcagt atcagggttt aatccgtaag agcgcatccg
    57121 ttctttacgg atattattta aaatatctgg gttattcgtt agtcccacga tttttttagg
    57181 atcgatctcc caaagctgtt tgggaatatg tgcttgtggg atcaaaggta aattggcaac
    57241 ttttaaattt ttgttagcta aaaacaagct caaaggcgtt ttggaagttc gggatacgcc
    57301 tagcaaaacg acatctgctt ctaaaaaacc acgaggatct ttcccatcat cgtattttac
    57361 agcaaattcc attgctttga tccgtttgaa atagttctca ttcaataaat ggagggcacc
    57421 aggttgccga attggcttga taccagttaa acgttcaatt tctgatatcg gtggcgtcat
    57481 cacatcaaaa ctaaataatt gatgttcttc acaaaaagaa cgtgttatct cgatcagttc
    57541 ttgattgatt aatgtatgca ggacaagtgc tttttcttct aatgcatctt gcaatgcctg
    57601 ccttaatgtt ttttcatctg tcacgaacgt tctgcggaat aggttgaact caacggtagg
    57661 atactgagcc atagtagctt gcgctagttt tgtcgcagtt tctccagcag agtcggagat
    57721 gacaaaaaaa gtaacgattt ctgtagaatc ggaagacatg gataaaacct cacttgcatt
    57781 ttttttatgt ttattatacc atactctaga atgcgtactt cgtaatcatt ttgatttgga
    57841 ggaataagtc atgaaaaaac agacattgat cgaacaatca ttagaaacat tgaaaaataa
    57901 cggttttaaa tatactaaaa aaagagaagc attgttaact tatttagtga agcgtaaccg
    57961 ctacgtatct gctaaagaag tttttgacta tatgaatcag gaattcaaag gggtaagtta
    58021 tgatacgatt taccggaatc tccatgattt tgcagagatc gatttactgg aagaaaccga
    58081 tttaaatgga gaaatgaagt ttcgttttca ttgctgtcag gggaaaatcg gccatcacca
    58141 tcattttatc tgtacagtgt gcggaacaac gaaagaaatc catatgtgtc cgatgaatta
    58201 tttcgaagaa cagctaggtg gatgcacgat cgaagggcat agattcgaga ttttcggaag
    58261 atgtgaaaat tgtcaataag gatttaaata aaataacatt tgataatttt aaaaaaaagc
    58321 aagatttcct tgacggtcaa aacagcatta gatataatat ttacaggaca gtcttgtttt
    58381 ttgagatata tttcaataac aattacggtt actttttaag ctcggaggga gggaattaac
    58441 atgtcaaaaa cagtcgttcg caaaaacgaa tcacttgacg atgctcttcg tcgcttcaaa
    58501 cgttccgtgt caaaagcggg tactttacaa gaatctcgta aacgtgaatt ctacgaaaaa
    58561 ccaagtgtaa gacgcaagaa aaaatctgaa gcagctagaa aacgcaaaaa attctagttc
    58621 tgtgatgaat tggagttggt agtgtgtcac tactaagtag attaaacgat gacatgaaag
    58681 cagcgatgaa agcgaaagat aaggaatctt tacaagtcat ccgaatgatc aagtcatcta
    58741 tacaaaacga gcagattaaa gaaggtcacg acttgacaga agaagaagaa ctaacggtgt
    58801 tgtctcgtga aatgaaacag cgacgtgatt ctttgcatga gtttgaagaa gcaggacgtg
    58861 acgatttagc tgaaaaagta aaaagtgaaa ttgtaatagt cgaaaaatat atgccggaac
    58921 aactttccga cgaagaaatt cgacaacttg ttcaagaagc aatcactcaa actggtgctt
    58981 catcaatgaa agaatttggc aaagttatgg gtgcaattat gcctaaagtc aaaggaaaag
    59041 cagatggaaa ccaagtgaat gcgattgtga aagaactatt acaatcttaa
//
LOCUS       DAFKHN010000006        58906 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFKHN010000006 DAFKHN010000000
VERSION     DAFKHN010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 58906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.006"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..962)
                     /locus_tag="LY912_000382"
     CDS             complement(<1..962)
                     /locus_tag="LY912_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBM6954105.1"
                     /translation="MGSIIKIASKSRSIHNTISYMLNKQEDSELVTGIGVSNDLNAIE
                     EFKRTNEIFGDKGKIKLWHFTQSFDPLEDISAEKAHELGVKWAEKMFPNQSILVVTHT
                     DKGHVHNHFGISPNDQLTGKKMDIRKNDIRVLQAWNDNILIDNGINPLDMYKYNHLVA
                     DRENWKEREFRTENKISNREKIKLAVSEVAQYAKNYDDFHAELKKNHSIETYRFAKNQ
                     RIGYKLLDSEGELILKIGGKRLGQNYDMNYLDDLFTENKKAEQIQSKEVLTEIAIRHL
                     GKSLNGRADSRFNWQERAQRFELDNENIPFLRSSKDYEEFYDKY"
     gene            complement(947..1444)
                     /locus_tag="LY912_000383"
     CDS             complement(947..1444)
                     /locus_tag="LY912_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954106.1"
                     /translation="MAIDVSKLPLEERRKRYKRNEDSRRQNRPIKFRVDDYQYQELEK
                     TADIFGLSVPMYVKKIAVDNAGKSLKYTDRQYKEINFHLLAIGRNLNQLVKTANYLRV
                     QLNKKDTEIQKEEHQSVYLSFTTKQERLKRLYAEKNDLMIQIKSISDPLNRLEKELNK
                     LWARL"
     gene            complement(1593..1931)
                     /locus_tag="LY912_000384"
     CDS             complement(1593..1931)
                     /locus_tag="LY912_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954107.1"
                     /translation="MARKKQKSIADLKKELAELERKLYPELGKYVYEKTGISSVKEFE
                     ETFEINQKGTQEKWQKAVNFANSEFTLVHEFLASDQLMETKFQQFLRRKGETAYRIFY
                     REEAQEESVR"
     gene            complement(1935..2120)
                     /locus_tag="LY912_000385"
     CDS             complement(1935..2120)
                     /locus_tag="LY912_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954108.1"
                     /translation="MQLILQISTHDFLELDELCESVKKATNEKITVTNYIELMIQEEL
                     MMKNELMNELSHIQKGA"
     gene            complement(2134..4686)
                     /locus_tag="LY912_000386"
     CDS             complement(2134..4686)
                     /locus_tag="LY912_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954109.1"
                     /translation="MKIIKKKIDNRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TESQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAVVDGIQNMIPEVLDLF
                     SFVESAGLNKVYQSVLNTVVIGLMVLSLVIIGYKMVTGKGTVDLKSVGMNVVMSIVLI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     MIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENSTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISTNIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNSGGNDQTEGEERKPERNFGQSLSQKANKTGKTLGYARERGLSGLASDGATMAS
                     ERATKPFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPIVAKNKEDETGKYADSMPI
                     RLSDRKDGAKIENADRIMSSSERMREAMKNIAESNTNYASAIQQKVQQDIEERKNAMH
                     GQAKSAEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKN
                     SNTGLEKSVKENLQNSTSSQDRRSVDVRENLHNTTSSQSGNRTVDVRENVQSSSTGQT
                     RTVDVRLNLQDTTSSQSGNRTVDVRENVQSSAPNQPKTVEVRETRAEASQGDKTQKIN
                     IVEERKERPNEKVIVEQEVKEKKRQRFTYENNPLFQDISDKPNPLFDSLFKK"
     gene            complement(4673..4891)
                     /locus_tag="LY912_000387"
     CDS             complement(4673..4891)
                     /locus_tag="LY912_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954110.1"
                     /translation="MIENHLVDKIYCLDHNADTLELIESICSNTIVLDLRAVNDDYVT
                     HIIVNKKMAQKLSESLKKWAEGGNNENN"
     gene            complement(4884..5624)
                     /locus_tag="LY912_000388"
     CDS             complement(4884..5624)
                     /locus_tag="LY912_000388"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954111.1"
                     /translation="MREKLKKLGDKKRHTFQGTFEFNGYKKDKYKFGQEYENATFMLS
                     NLKIVQGDNLELVTDHIWMNLTKQFLKFGWLKKGDMVQFDGRIKSYSSKKGINYKIER
                     PSKVKVFRKGTEINESSALKISTRYEIVEDIKRQNREYYEARDFFFENYFSVPRYFKL
                     KEKWPEIQAVVAINENRYTSEQFKQVFKDRDSLVDLYKKIQETDKYNLQKEFYNGLVS
                     NKNRIDLNEVEGYLHKIENFDYGRGYFD"
     gene            complement(5757..6632)
                     /locus_tag="LY912_000389"
     CDS             complement(5757..6632)
                     /locus_tag="LY912_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HBM6954112.1"
                     /translation="MAEKRMLAKSFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYTKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKFDMILQSGQVEPLRVDLMEKWYPAGIPCDVKSDTQLSQDQNSQDQ
                     TNQDKDSIEEINQDQNSFFENIINQKGIQIITRLGDRYTEVQREKYLKLIASMKDSIE
                     REYKIEIRGQDYFDITNKMLTRLFNSINEKLNLGEEIDEMKFINTTARNHWEDIAKQE
                     KASRLDMLETLKKIG"
     gene            complement(6802..7083)
                     /locus_tag="LY912_000390"
     CDS             complement(6802..7083)
                     /locus_tag="LY912_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954113.1"
                     /translation="MEQIGVSVMLNTDQTNQLKTHVFEVTKEAIDQARIDSGLERPFL
                     KGKEMAKFLNVSYGTFLKFKRLGLPIIVVDTIELYSKEEVKKWMLQHQI"
     gene            complement(7138..7335)
                     /locus_tag="LY912_000391"
     CDS             complement(7138..7335)
                     /locus_tag="LY912_000391"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6954114.1"
                     /translation="MFQINEDFSIRIRERRGKLMITKTKAAELIGISRQTLKKIECFE
                     VQSVSKNVYQKIIGWLLKSDY"
     gene            7502..7876
                     /locus_tag="LY912_000392"
     CDS             7502..7876
                     /locus_tag="LY912_000392"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6954115.1"
                     /translation="MTQKNRIKETREEQNLTLKELSNLSDIPYQTLRNYEIGKRKPRN
                     DEVWWKLGTILNVRGPYLKGEDSFKTNDELHIYYLKKSHTNFELSKKEEIIDIIDKLN
                     EDGLDEALRQLALLSKIDDFKR"
     gene            7966..9132
                     /locus_tag="LY912_000393"
     CDS             7966..9132
                     /locus_tag="LY912_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBM6954116.1"
                     /translation="MSIQKYKTKSGTRYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDMGYHRPSNDLFRTVYEEWLPSYKNRVQETTYQRTKDLFRLHILPKFG
                     DKSISKITPIYCQNAINEWAVKYTNIKQLKSYSSQIFEYAIFAELLQRNPMTNTKLPK
                     QEKKESENYFSLEELKEFLEILNKEESLKHILIFQLLITTGVRKGELSALRWADINFE
                     EQLLHIGKSYATIRTEDPNATRKTIRIQKNTKNVSSERILPIDTQTIEMLKLWKKEQA
                     EVLLQFGINANTKKQLIFTYVNANGDVNQPLHADYSNNIMRRLEKKYKFKHVTIHGLR
                     HTHATLLLEGGASIKEAQDRLGHKNAETTLNTYSHVTEKAQRNAVDKFIAYTGL"
     gene            complement(9231..9623)
                     /gene="rpsI"
                     /locus_tag="LY912_000394"
     CDS             complement(9231..9623)
                     /gene="rpsI"
                     /locus_tag="LY912_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBM6954117.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(9639..10082)
                     /gene="rplM"
                     /locus_tag="LY912_000395"
     CDS             complement(9639..10082)
                     /gene="rplM"
                     /locus_tag="LY912_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBM6954118.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(10601..11068)
                     /locus_tag="LY912_000396"
     CDS             complement(10601..11068)
                     /locus_tag="LY912_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBM6954119.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(11188..12726)
                     /locus_tag="LY912_000397"
     CDS             complement(11188..12726)
                     /locus_tag="LY912_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBM6954120.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            12806..13492
                     /locus_tag="LY912_000398"
     CDS             12806..13492
                     /locus_tag="LY912_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBM6954121.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(13693..14220)
                     /gene="msrA"
                     /locus_tag="LY912_000399"
     CDS             complement(13693..14220)
                     /gene="msrA"
                     /locus_tag="LY912_000399"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBM6954122.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14304..14981)
                     /gene="pgmB"
                     /locus_tag="LY912_000400"
     CDS             complement(14304..14981)
                     /gene="pgmB"
                     /locus_tag="LY912_000400"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBM6954123.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(14978..16108)
                     /locus_tag="LY912_000401"
     CDS             complement(14978..16108)
                     /locus_tag="LY912_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBM6954124.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(16108..18291)
                     /locus_tag="LY912_000402"
     CDS             complement(16108..18291)
                     /locus_tag="LY912_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBM6954125.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(18288..19313)
                     /locus_tag="LY912_000403"
     CDS             complement(18288..19313)
                     /locus_tag="LY912_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBM6954126.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(19358..20185)
                     /locus_tag="LY912_000404"
     CDS             complement(19358..20185)
                     /locus_tag="LY912_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBM6954127.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(20182..21249)
                     /locus_tag="LY912_000405"
     CDS             complement(20182..21249)
                     /locus_tag="LY912_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBM6954128.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(21275..22111)
                     /locus_tag="LY912_000406"
     CDS             complement(21275..22111)
                     /locus_tag="LY912_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6954129.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(22108..22977)
                     /locus_tag="LY912_000407"
     CDS             complement(22108..22977)
                     /locus_tag="LY912_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6954130.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(23047..24330)
                     /locus_tag="LY912_000408"
     CDS             complement(23047..24330)
                     /locus_tag="LY912_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBM6954131.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(24344..26029)
                     /locus_tag="LY912_000409"
     CDS             complement(24344..26029)
                     /locus_tag="LY912_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBM6954132.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            26304..27329
                     /locus_tag="LY912_000410"
     CDS             26304..27329
                     /locus_tag="LY912_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6954133.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(27924..31598)
                     /gene="rpoC"
                     /locus_tag="LY912_000411"
     CDS             complement(27924..31598)
                     /gene="rpoC"
                     /locus_tag="LY912_000411"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBM6954134.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARILMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(31656..35273)
                     /gene="rpoB"
                     /locus_tag="LY912_000412"
     CDS             complement(31656..35273)
                     /gene="rpoB"
                     /locus_tag="LY912_000412"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBM6954135.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            36001..36969
                     /locus_tag="LY912_000413"
     CDS             36001..36969
                     /locus_tag="LY912_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6954136.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            36987..37892
                     /locus_tag="LY912_000414"
     CDS             36987..37892
                     /locus_tag="LY912_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954137.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            37889..38695
                     /locus_tag="LY912_000415"
     CDS             37889..38695
                     /locus_tag="LY912_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6954138.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            38831..39820
                     /locus_tag="LY912_000416"
     CDS             38831..39820
                     /locus_tag="LY912_000416"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBM6954139.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(40137..40661)
                     /locus_tag="LY912_000417"
     CDS             complement(40137..40661)
                     /locus_tag="LY912_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBM6954140.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            40948..42816
                     /gene="scm"
                     /locus_tag="LY912_000418"
     CDS             40948..42816
                     /gene="scm"
                     /locus_tag="LY912_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBM6954141.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSSDSSTSSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSST
                     TTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNR
                     TNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(42971..43957)
                     /locus_tag="LY912_000419"
     CDS             complement(42971..43957)
                     /locus_tag="LY912_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBM6954142.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(43980..44546)
                     /locus_tag="LY912_000420"
     CDS             complement(43980..44546)
                     /locus_tag="LY912_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBM6954143.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(44560..44976)
                     /locus_tag="LY912_000421"
     CDS             complement(44560..44976)
                     /locus_tag="LY912_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBM6954144.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(45433..47367)
                     /locus_tag="LY912_000422"
     CDS             complement(45433..47367)
                     /locus_tag="LY912_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBM6954145.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            47648..48604
                     /locus_tag="LY912_000423"
     CDS             47648..48604
                     /locus_tag="LY912_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBM6954146.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            48694..49797
                     /locus_tag="LY912_000424"
     CDS             48694..49797
                     /locus_tag="LY912_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBM6954147.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            49810..50763
                     /gene="menA"
                     /locus_tag="LY912_000425"
     CDS             49810..50763
                     /gene="menA"
                     /locus_tag="LY912_000425"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBM6954148.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(51698..53044)
                     /gene="gor"
                     /locus_tag="LY912_000426"
     CDS             complement(51698..53044)
                     /gene="gor"
                     /locus_tag="LY912_000426"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBM6954149.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(53178..54431)
                     /locus_tag="LY912_000427"
     CDS             complement(53178..54431)
                     /locus_tag="LY912_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBM6954150.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(54437..55360)
                     /locus_tag="LY912_000428"
     CDS             complement(54437..55360)
                     /locus_tag="LY912_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBM6954151.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(55581..58073)
                     /locus_tag="LY912_000429"
     CDS             complement(55581..58073)
                     /locus_tag="LY912_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBM6954152.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(58080..58547)
                     /locus_tag="LY912_000430"
     CDS             complement(58080..58547)
                     /locus_tag="LY912_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBM6954153.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(58683..58756)
                     /locus_tag="LY912_000431"
     tRNA            complement(58683..58756)
                     /locus_tag="LY912_000431"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58720..58722),aa:Arg,seq:acg)
     gene            complement(58814..58887)
                     /locus_tag="LY912_000432"
     tRNA            complement(58814..58887)
                     /locus_tag="LY912_000432"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58851..58853),aa:Pro,seq:tgg)
BASE COUNT        16981 a        12419 c        10472 g        19034 t
ORIGIN      
        1 ttatatttat cataaaattc ttcataatct tttgatgatc taagaaatgg tatattctca
       61 ttatctaatt caaagcgttg cgctcgttct tgccaattaa atctactatc cgctctacca
      121 tttaacgatt taccaagatg tcgaatagca atttcagtga gtacctcttt agattgaatt
      181 tgctccgctt ttttattttc tgtgaacaaa tcatcaagat aattcatatc atagttttgc
      241 cctaaacgct ttccgccaat ttttaagatt aactcgcctt cagaatctaa gagtttgtac
      301 ccaatacgct gatttttggc aaaccggtaa gtctcaatag aatggttttt cttcaattcc
      361 gcatgaaaat catcataatt tttcgcatac tgagcaactt cagaaacagc tagttttatt
      421 ttttctcgat ttgaaatctt attttcagtt ctaaattcac gttctttcca attttcacga
      481 tctgcaacta aatgattata cttatacata tcaagtgggt taattccatt atcaataagt
      541 atattatcat tccaagcctg caaaactcga atatcattct ttcgaatatc cattttcttt
      601 cctgttagct gatcgtttgg cgaaatacca aagtgattgt gaacatgccc tttgtctgtg
      661 tgtgtgacaa ccaaaattga ctggttagga aacatttttt ctgcccactt aacacccaac
      721 tcatgtgctt tttcagcgga aatatcttct agtggatcaa agctttgtgt aaaatgccaa
      781 agctttattt tccctttatc accaaaaatt tcattggttc gtttaaattc ctcaatagca
      841 tttaaatcat tcgatacgcc aattcctgtc acgagttcag aatcttcttg tttatttaac
      901 atatatgaaa ttgtattatg aatactccta ctttttgaag caatttttat aatcgagccc
      961 ataacttatt caactctttt tccaagcgat tcaatggatc gcttattgat tttatttgta
     1021 tcattaagtc atttttttca gcatatagcc gctttaatcg ctcttgctta gttgtaaaag
     1081 ataagtaaac actctgatgt tcttcttttt gtatctcggt atctttttta tttaactgaa
     1141 cacgcaaata atttgctgtt ttcactaatt gattcaaatt tcttcctatt gctagtaaat
     1201 gaaaattaat ttctttatat tgtcgatcgg tatattttag acttttccct gcgttgtcta
     1261 ctgcgatttt cttcacgtac attggaacag ataaaccaaa aatgtctgct gttttttcta
     1321 gctcttggta ctgataatcg tctactcgaa actttatcgg cctattttgt cgtcgactat
     1381 cttcattacg tttatatcgc tttcgccttt cttctaatgg tagtttactg acatcaattg
     1441 ccatgcgcac ttctcctttt caatattatt tttaagttca aaagaagcaa gcgaggggaa
     1501 agggaaccct tccccgcttg tcgagggagt aaactcccta cgagcaccct catgctccgc
     1561 attttatcga gattagatag ccgataaatc agctacctaa cactttcttc ttgcgcctct
     1621 tctcgataga aaattcgata cgctgtctct ccttttcttc tcaaaaattg ttggaatttc
     1681 gtttccatca attgatcgct tgcaagaaat tcgtgtacta gggtaaattc gctattcgcg
     1741 aaatttaccg ccttttgcca tttttcttga gtaccttttt gattaatttc aaaagtttct
     1801 tcaaactctt ttactgatga aattcctgtt ttttcataga catactttcc cagttcggga
     1861 taaagttttc tctccaactc ggcgagttct tttttcaaat ctgcaattga cttttgtttt
     1921 ttccttgcca tttttcatgc tcctttttgt atgtgactaa gttcattcat aagctcattt
     1981 ttcatcatta attcttcttg aatcatcagt tcaatataat ttgtgaccgt gattttttca
     2041 tttgttgctt tctttactga ttcacataat tcgtcaagtt ctaagaaatc atgtgtacta
     2101 atctgtagaa ttaattgcat gacaatcacc tctttatttt ttaaatagac tatcaaacag
     2161 cggatttggt ttatcagaaa tatcctgaaa cagtggatta ttttcataag taaatcgttg
     2221 acgtttcttc tccttcactt cttgttctac aatcactttt tcgttaggtc tttcttttcg
     2281 ttcctcgaca atatttattt tttgcgtctt atctccctga cttgcttcag ctcttgtttc
     2341 acgtacttct accgtttttg gttgatttgg cgcactactt tgtacatttt ctcgtacgtc
     2401 tactgttcga tttccacttt gactacttgt agtatcctgt aagtttaatc gaacatctac
     2461 cgttcttgtt tgacctgtac tgctactttg cacattctct ctgacatcca ctgttcgatt
     2521 tccactttga ctacttgtag tattatgcaa gttttctcga acatctactg agcgcctatc
     2581 ttgactactt gtagaatttt gtagattttc tttaaccgat ttttctaatc cggtatttga
     2641 atttttagct tcttggattc tttctttggt caacgcttct ttttcgtcca tattagctcc
     2701 tgtacgccct tctacacgtt tccttaacat ttcctcacga ttcattgctt caggcgtgta
     2761 ttttgcttcc tgtcgcttct gattaattaa ttcttcagca gacttagctt gaccgtgcat
     2821 agcattttta cgttcttcaa tatcttgttg aactttttgc tgaattgcac ttgcataatt
     2881 agtatttgat tcagcaatat ttttcattgc ttcacgcata cgttcagaac tagacataat
     2941 tctatcggca ttctcaatct tagccccatc ttttctatcc gaaagacgta ttggcataga
     3001 atcagcatat tttccagttt catcttcttt gtttttagct actataggtt tgctattttt
     3061 attaatagcg gacacggtac catcatctaa accttctttg aatttattct tggtatcatt
     3121 agccatatca cgcatactct taaatggttt tgttgctctt tcactagcca ttgtagctcc
     3181 atccgaagct aagcctgata atccacgttc acgagcatac ccaagcgttt tccccgtttt
     3241 attagctttt tgagaaagtg attgaccaaa gttgcgttca ggttttcgtt cttccccttc
     3301 cgtttgatcg tttccaccac tatttttccc acctttagat cggttcatgc cacctgttcc
     3361 tttacgaaac agcattgcac ccattccaaa agcagaagca agttgcccat agccttcttt
     3421 gagtccaata tccacaccaa agtaacgcat gactgttcca ctgcctttga ttaaaacaaa
     3481 cacagcacag atataagcaa ttgtttttat aaaaatattt gttgagatac cttcgccagt
     3541 atttaagtaa tttatgaaca ttgcaaacat agataatcca aacccttgaa atccgactgt
     3601 caaatagcac tgtaaaatat ctgacaaaac ttgttttgat cgttgtcctg tttctaagtc
     3661 agtagcaaat actaaaactc cgagtacacg tttgaatgct agctcgagta ttgctgtaat
     3721 tataatgaaa gcactaaaaa catacgctac cgctaaagca atcaatccaa atgaaattcc
     3781 ccacaggttc gcttgatagc gataatatcc tgatttgata ccatcaacaa aggttgacaa
     3841 aaaattatct gaaaatttag tagcaacaaa ttcattatca gaattttcaa ctaattcata
     3901 acgcaggtta tcagctgttg agttctcttt ttccatttta tcaattacat tatctgtcaa
     3961 tacttgcgta agatccgttt tccaaaaatt ttcttttgtt agattgttcc gatcattcgt
     4021 tttatcgatc atggaatatt gatccgtttt attgatataa gctaaatcag taaccccttg
     4081 ttcaatcagc gaccatgcca caccgccatc ttgattgtta atactagttg cgtcattata
     4141 aagagtcttt gcaaacatta ttcctgaaag tttttctgtt gatccaatca aagtcggcat
     4201 taaaagaatt aatactatcg acattacaac attcattcca acagatttta gatcaactgt
     4261 tccttttcca gtcaccattt tataaccaat aatcactaat gagagtacca ttaaaccaat
     4321 aacaactgta tttaaaactg actgatagac tttgttcaat ccagcacttt ccacaaagct
     4381 aaacaaatct aaaacctcgg gaatcatatt ttgaatgcca tcgacaacag cgaacattga
     4441 ttttataaca gaccaaccta tccacatacc gaactggctg taaaaatttc cgttatattt
     4501 tttaagataa ttctgataaa gtggattagt taaaaactca gtttgactct cagtatcatc
     4561 aaaccagttg aaaatactgc cttctgcaac gttactcgta aaaataatca tagctatgag
     4621 aataagaaaa ctaatcaaca accaatttat ttttctatta tcaatctttt ttttaattat
     4681 tttcattgtt acctccctca gcccattttt ttaggctctc agaaagcttc tgagccattt
     4741 ttttattaac gatgatgtga gttacgtaat catcattaac agctcttaaa tctagaacaa
     4801 tagtatttga gcagatactc tcgattaact caagagtatc tgcgttatga tcaagacagt
     4861 aaatcttatc tactagatga ttttcaatca aaataacccc tcccgtagtc aaagttctca
     4921 attttatgaa gatatccctc tacttcattt aaatcaattc tattcttatt gctgactaac
     4981 ccgttgtaaa attctttttg tagattatat ttatctgttt cttgaatctt tttatataaa
     5041 tcaaccaggg agtccctgtc tttaaaaact tgcttgaatt gttcgcttgt atatcggttt
     5101 tcattaattg caacaactgc ttgaatttca ggccattttt ctttcaactt aaaataacgg
     5161 ggaacgctga aatagttctc aaaaaagaag tctcgtgctt catagtattc tctattttgt
     5221 ctttttatat cctcgacaat ttcgtatcgt gtagagatct tcaaagctga actttcgtta
     5281 atttctgttc cttttcgaaa gactttcact tttgaagggc gttcaatttt ataatttatc
     5341 ccctttttac ttgaataact tttgatacga ccatcaaatt gaaccatatc tccttttttt
     5401 aaccacccaa attttagaaa ttgtttagtt aaattcatcc aaatgtggtc tgtgaccaac
     5461 tctaagttat ccccttgaac aatttttaaa ttcgataaca taaaagtagc attttcatac
     5521 tcttgaccaa acttgtattt atccttttta tatccgttaa attcaaaggt accttgaaat
     5581 gtatgccgtt tcttatctcc taattttttc aatttttctc tcaaaataat caactccatc
     5641 atttaatata tttttgtgat ggtagatact ctcgattaac acaagagtat ctgcgttgta
     5701 atcaagacaa taaatttgat atattaaccg tttttcaatc atattattaa tcctttctaa
     5761 cctatttttt tcagtgtctc tagcatatcc agtctactag ctttttcttg cttagctatg
     5821 tcctcccagt ggttcctagc tgtggtgttg ataaacttca tttcatcaat ttcttcaccg
     5881 agattcagtt tttcatttat agaattaaaa agtcttgtta gcattttgtt tgttatatca
     5941 aaatagtctt gacctcgaat ttctatttta tattctcttt caattgaatc tttcatacta
     6001 gcaatcaact taagatactt ttctctttga acttcagtat atctatcacc tagtctggta
     6061 attatttgaa ttcctttctg atttataata ttttcaaaaa aggaattctg atcttgatta
     6121 atctcttcta tactatcctt atcttgatta gtttgatctt gactattctg atcttgactt
     6181 aactgtgtat ccgatttgac gtcgcatggt ataccagctg gataccattt ttccatcaga
     6241 tcaactctta atggttctac ttgaccagac tgcaaaatca tatcaaattt tattggcttt
     6301 agctttgaga aaaattctgg ttttaagttc aataacttga atcgataaat agaaggttta
     6361 tacctatcga ttcgtatatt ttgattttgt aaccagtggg gtagaaacgc taacaaatct
     6421 tcatttaaaa aaaatacaaa accttttgta aaaagtatct ttacatcatc atcgggtgtt
     6481 ccgagcattt tcgtgtatgg ataagcttcg acaattccgt catcatctgc gtttgtgttc
     6541 agatatacgt ataataattt tgctgaatct gacatcttca taaaacttgc attatttaaa
     6601 aatgatttag ccagcattcg tttttctgcc ataaaaatca cacttcttcc tatttgaatg
     6661 ttaaaatgta gtcaaataaa gtttagctag aactttatta ttgagcgttc ctagtggtct
     6721 gcaaactaac gggaacactc ttttttattc ttattaaaac cagcaatact agttcacctt
     6781 ctttcatcct tttacatcca attaaatttg atgctgtagc atccattttt ttacctcttc
     6841 ttttgaatat agttcaattg tgtcaaccac gataataggt aatcctaacc ttttaaactt
     6901 cagaaaagtt ccatatgata cgtttagaaa ttttgccatt tcttttccct taagaaaagg
     6961 tcgttctaat ccgctgtcta ttcttgcttg atcaatagct tcttttgtca cttcaaacac
     7021 atgtgtcttc aactgatttg tttgatcagt attcaacatt acactgactc cgatttgctc
     7081 cattaaaaat tcccactttc atattttcat caataagcca actcgccaag ttgtttgtta
     7141 ataatctgat ttcaataacc aacctattat tttttgataa acatttttcg acacactttg
     7201 aacttcgaag cattcaattt ttttaagagt ttgccttgaa attccaatta attctgctgc
     7261 tttagttttc gtaatcatca actttcctcg tctctctcga attcttatac taaaatcctc
     7321 attaatttga aacataaaca tccctccatt tttatttttg catttatccg tttatccgat
     7381 gtcggataaa tagattttag tatatattat tttgatagtc aattaaaaat atacattttg
     7441 gataaaattg ttcatttttt tatccaaatc atatattata gatagtaaga ggtgaacttc
     7501 attgactcaa aaaaacagaa ttaaagaaac tcgcgaagaa cagaatttaa cacttaaaga
     7561 acttagcaat ctgtcggata ttccgtatca aactttgaga aactatgaga ttggtaaaag
     7621 aaaacccaga aatgatgaag tttggtggaa gttaggtacg attttaaacg tccgtgggcc
     7681 ctacttaaaa ggagaagata gttttaaaac aaatgatgaa ttgcatattt attatctaaa
     7741 aaaaagtcat acaaattttg aactgtctaa gaaagaagaa attatagata taatagataa
     7801 actaaacgaa gacggtttag atgaagcctt acggcagtta gcactattat caaaaataga
     7861 tgatttcaag cggtaactta cttatcatca tgtagactat caggtatcat aaactaattc
     7921 ctcaatcagc caactcgcca agttatcaga ttggagagat tagttatgtc aatacaaaag
     7981 tacaaaacaa aaagcggtac acgatatagt gtccgcttat atgttcgtaa agatgaaaat
     8041 gggaagcaag aatactatgt aaaaaaaggc ttcaaaactg aaaaagaagc caagttacac
     8101 gaagcaagaa aaaaggtcga gattgaagat atgggctatc acagaccttc taatgactta
     8161 tttagaacag tctatgaaga atggttgccg tcttataaaa atcgtgtaca agaaacgact
     8221 tatcaacgaa caaaagacct ttttcgcttg catatcctgc caaagttcgg agacaaatcg
     8281 atttctaaga ttactcctat ttactgtcag aatgcaatca atgaatgggc tgtaaaatat
     8341 acaaatatca agcaacttaa atcctacagc tctcaaatat ttgagtatgc aatcttcgca
     8401 gaattgttac agcgtaaccc tatgacaaat accaaactgc caaaacaaga aaagaaagaa
     8461 tccgaaaatt atttctcact agaagaatta aaagagtttt tggaaattct caataaagaa
     8521 gagtctttaa aacatatcct gatctttcaa cttttaatta ctaccggtgt tcgcaaaggt
     8581 gaattatcag ccctacgctg ggcagatatt aattttgaag aacagttact acacatcgga
     8641 aaaagttatg caacaattcg cactgaagat ccgaatgcta ctagaaaaac aatcaggatt
     8701 cagaagaata caaaaaatgt ctcttccgaa cgaattttac cgattgatac tcaaaccatc
     8761 gaaatgctga aactttggaa aaaagagcaa gcagaggtac ttttacaatt cggcattaat
     8821 gcaaatacca aaaagcaact tatctttacc tatgtaaatg caaatggcga tgttaaccaa
     8881 cctttacacg cagattattc caataatatt atgagacgtt tagagaagaa atataaattt
     8941 aagcacgtta ctattcatgg attgcgacac actcacgcca ctttactttt agaaggcggt
     9001 gcgagcatta aagaagcaca agatcgattg ggtcataaaa atgctgaaac tacgctcaat
     9061 acttattccc atgtaactga aaaagcgcaa cgaaatgcgg tagacaagtt tattgcttac
     9121 actggattat agacaaaaaa gttgccgtca ttaccttttt cattaccaca acgaaaaaaa
     9181 gcaccttcca actgaatgga aagtgcttga aatcgttggt ataacaacga ttaacgctta
     9241 gagaattgtg aagctttacg agctttctta agacctggtt ttttacgttc gaccatacgt
     9301 gcgtcacgag taagtaagcc agcacgttta agagctaaac ggaagtcagg atcaacttct
     9361 agcaatgcac gagcgatacc atgacggata gctcctgatt gtccagcgta tcctccgccg
     9421 tttacgttaa caaatacgtc atatgcgcct tttgtttcag taacagcgaa aggttgattg
     9481 attacttcac gcaagtcagc atgtggaatg tattcttcaa catctttttt atttacagta
     9541 attttgccag ttcctggtac tagacgtacg cgagcaactg cgtttttacg acggcctgtg
     9601 ccgatatatt gaacttgtgc caatgaaatt ccctcctatt agattaagtt tgtgatgtct
     9661 aaaacttctg gttgttgtgc tgcatgtgga tgttctgctc caccgtatac gttcaatttt
     9721 gtaaattgtt tgcggcctaa agtgttttta ggaagcatac cttttacaga agtttcgatc
     9781 aaacgacgag aatttttagc acgcaattcg ccagcagtga ttgatttcaa tcctcctggg
     9841 tagttgctgt gacggtaata aattttgtca gtcgcttttt tacctgttaa tttcactttg
     9901 tctgcattga tgacgatgac gaaatcgcca gtatccaaat gaggtgtgaa agttggttta
     9961 tttttaccac gtagtacaga tgcaacaact gttgaaagac gtcccaatgg aacatcagtt
    10021 gcgtctacta cataccattt acgttctact tcgcctggtt tggccatata tgttgtacgc
    10081 acgttatttt cctccaattt aagttctgat gtttgacata cacttcgagt ttccggggct
    10141 ctttgtgggg caaacaatac catttaacat attacccgct aatctagtca atgtcaacgt
    10201 ttttctgctt gattgaaaaa tttatatgaa actttacttc ttttctttct tttatataaa
    10261 agggtcgttt cctgtcaaaa tgaaaaacaa aaagaggctg tgacaaaagt cttgtcacaa
    10321 ccccttattt tgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatc
    10381 cataaaacat aagaagctgt tttttaaaat tgtttcttgt gactcggagc tgaacggcag
    10441 gcttacaacc tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa
    10501 cggcaaaata tgaggaacta ttttgacgtt tgtttctcta atactcaggt caaaacgctg
    10561 atttcacaac ctctttttcg gtcaagttca acaacagttt ttacgcgtcg atctctggcg
    10621 ctttgcccaa atgagcttgg atcatccaga tacgtttttc tgtggctgtt ttgaattcga
    10681 taaagatatc ttgtgttgga tcgtcgcctt cttctccaga aacttcgatt cctttttggt
    10741 aaagatctgc tagataacga tagcctgcaa caagtgtttc caaacgttct ggaatagtac
    10801 gatcccagcg gccaatttca tcagggattt ttgtgttatc tgcaaattca cgcaatgtag
    10861 aataaggtga accgtctaat gtgatcaagc gttcggatac ttcatctaac tgagcgttca
    10921 aatcatccat gaactcatcc atcattgggt gcaatgtaag gaaacctggt cctctcatgt
    10981 accaatgtgt ttggtgaaca acaacagaca tttggcttag atctgcaact aattgattta
    11041 atacttcttt ggtttgttgg aatttcatct ttcttgcctc ctaacatttt cttacactta
    11101 aaataatagt agactttcaa tgaaaagtac aacaaaatca tttacctgag aacgattttc
    11161 agttcgcttt tttatccgta aagccaatca tttttcagaa tcagctaatt cttctcgcag
    11221 ttgagcaaat tgctgataag tctgtgctaa atgcttttgt gtcgaaacaa ataatggata
    11281 gattttctga tattttttat gatcagtttc ttgtactcca acttgctctt tcaattctat
    11341 caattcctgt gcttcactga tactttggat ctttccgatg cttctccagc ctaaaatcac
    11401 agctcctaat gcggatgctt ctgtgacagt agggaaaaca agcgggtaac ccagtacatc
    11461 agccatcatc tgacgaaaaa tcggagattg agcaaacccg cctgtagcac ggatctctgt
    11521 gagctgattt tcctggcaaa ctccttttaa aatccgataa aggttgagac agatcccttc
    11581 tagaatcgcc ttcatcattt ctttttctgt atgttgccgc tgtaaaccga taaaactgcc
    11641 aaacgcatct gcgtcccaaa gcggtgctcg ctcaccaagt aaatagggat gaaaaatcag
    11701 accattggca cccgctggca caaaagcgat agccgaaagc agtgcatcat atggattttc
    11761 tcctttttct ttagcagatt gaacgacttc ctgtaaaaat gtatgccctg cccaatcaaa
    11821 gatgccagca ccattgctag tcgctcctcc cactacccaa tgtttctgat ccagaacata
    11881 acaaaacgtc tccatttctg gatggaactg aggctgagta gtaataaaac gaagtgctcc
    11941 gctcgttcct acggtcaaag cggcgatcgt atcaccaaaa gcacctaacc ctagattaga
    12001 aagcggcccg tctgcccctc ccaaaacaaa tgatatatca tttggcaaac ctagttctgc
    12061 tgctgttttt gatggtagac ctgttacttg ataggtggaa ggaaagactt gcggcaattg
    12121 ctctattcga atgttcaagt agtcaagcac ttcttctgcc cattggaatt catggatatc
    12181 aaaatatcca gttcctgaag ctgttccgta gtcgctgatc agttcgccaa acaatctata
    12241 aaagatatag tctttgatac cgacaaaata agcagttttt ttgaataatt caggttggct
    12301 gttttgcagc cacttgattt tgttcaatgg tgtcattgga tgaatcggcg tcccagtctg
    12361 ccgataaaat tctttgccaa gcacggtata tttcagtttt tctgcttcgt ccgctgctcg
    12421 gttatctgcc caagtgatca ttcgagataa cggtgttttc tcttcatcca acaatatcag
    12481 gccatgcatc gcagaggaga aggagacaaa ttgaatgatt gtgtctgaag gcaactgttt
    12541 aattacttct tttataacgg tgcagacacc ttgaaagatc aattcctgat cttgttctgc
    12601 catcccttgt gtttcttgga tcaaagggta gcgaaaataa gcggatgctg cttcttgggc
    12661 ttcatctgtg aaagcaactg ctttggtttg tgtggttccg atatctaatc cgattgaaac
    12721 gttcattttt tcacctcaaa ttttatgtat gtacaaaaat ttagtttaag cttgcgtatc
    12781 ttggttttga aaagggggag atggcgtgtt actttatttt atcattggtt gctgtatcgg
    12841 atcattttta tgtttaaccg cccagcggat tccgttaggt cactctatta tttatcctag
    12901 atctcattgt gtcaaatgct gtcgttcgct ttcttggtat gaattgattc cgattctctc
    12961 gatcatcgtc caacgatttc gctgccgcta ttgcaggtgt cggttgccct tctactattt
    13021 gttggcagaa gccttatgtg gtggtctttt tgcctggttc tttacttttt cttccgcaag
    13081 aaatttttcg acgttcatat ggatgctttc ggctttgcta ttttcgttga tggatttatt
    13141 ttacttcatg gtccattctc acacgctatt ctgttcttgg gcaattttat ggattttttg
    13201 gttgcaggcc ggcgtcttcc aatggcaaag tgtgctgtta acgtttatcg taggcggtgt
    13261 gtgccttcgc tatggtcaat cctatctcgg agctggcgat actctgttga tgctttcttg
    13321 gagtggtggc ttgtctctag aagagttgct tcagatcttg tttcttgcta gtctgtttgg
    13381 aatatccgtt ttttctgttt actttatctg tcataaaaaa aagttggaaa agctgccttt
    13441 cattcctttt ttgagcagtg cgttgctgat tgtccttcat cttaggtatt gaaaaaaggt
    13501 tgtgacaaac gacttgtcac aacctctgat atatagtgtt ctcttaccaa atccttgtga
    13561 cttggagcta ggcgacaggt tcacaacctc tccactaaat ggtgttcaat cagctgaccc
    13621 tcagtattag ctcaaaatgc tggttttaca acctctgata tacggtgttc cataagtagc
    13681 tttttcggct tcttatttct tgacgcccca atgtcgacga aggaaacctg cacgtccaga
    13741 accttctcga taaagattgt aatggagctt gtttttcttg taataatcct gatggtaatc
    13801 ttctgcagga taaaattcgc ttcttggttc gatttttgtc acgattggct tatcgaatcg
    13861 cccgctgtct tgcaatgctt gttttgaacg ctctgcaata tttcgttctt cttcatcatt
    13921 atagtagatc actggacgat aagaatcacc gcgatcagcg aactgtccta atgcgtcagt
    13981 cggatcggtt tgctgccaat agatttccac caactgatca taagaaataa cttctggatc
    14041 atattcgatc tctactgctt ctgtatgccc tgttgtgcct gttgttactt gttcataagt
    14101 tggatttggt acatgcccgc cagtataacc ggatgtcaca gaaatgatcc ctggctgctc
    14161 ttcaaatggt ttgaccatac accaaaagca tccgcctgcg aaaactgctt tttttgtcat
    14221 ataaaatccc ccttttttct catcatacct tgatttccaa aaggaggata acgttttgct
    14281 tgtgacagaa aaaacggaaa ctattatata cgtgatacgg cttctgataa atgccaaaac
    14341 gaacgtactt gatcaaaaac ggttaaatca ggaatcacat attcagcaga aggaagattt
    14401 atgttttcac ctattcccaa tacatgcatg ttaccagcca aagctgcttg acaaccagct
    14461 tctgaatctt caatgaccaa gcatgcattt ggcggtacat tcaattgctg tgctcctttg
    14521 agaaaaactt ctggatcagg ttttgctttt gatacttgcg tgccgtcaat aaggacatca
    14581 aaataacttg tcaaattcgt tttttctaaa atgaggcgtg catttttgct tgctgatccc
    14641 aatccgatct tgatgtttgt ttttttcaag tactcaagaa cagctattgc accaggcaaa
    14701 acggatgttt catccatttt ttgaatcgct tgaagatata gattgttttt ttgctcagca
    14761 aaggctgatt tctctttttc tgagaatttc tgttccattt ttccaaatga cagcaatcgc
    14821 tctagtgact cggttctgga tattcctttc agttgctcgt tttctttctc agtgaatgga
    14881 atggacagct ggttagctaa aaccagccac gcttcgtaat gataacgagc tgtgtctaca
    14941 agaacgccat ctaaatcgaa tagtgctgct ttgattttca tcgattacct ccttgaaaat
    15001 gaacgacttg aagtaaagat gcgatgtttt tagctgtgcg atgaagatta tcagtggctt
    15061 gctgtaaagc ttcttgtaaa ggcacagctg caggaaggat cggaaaaacg gccgaaatgc
    15121 caacatctgc tgctttttcg cttcctttac caacacttcc gcaaatagct atcacaggaa
    15181 cgccctctgg tactcttcta gcaatcccaa ctggcgcttt tccttttaga ctttgtccat
    15241 ctagacgtcc ttcgcctacg attacgaggt ctgcttgctg tacccgttta tcgaactcca
    15301 gtaaatccaa tacgtagtcg atgccagaga ctattttccc tgaagcaaat gctaacagtc
    15361 ctgcacccat tccaccacca gcactactgc ccgatgcctc gattacttga ggggcaaatc
    15421 tcatataaaa atcatgcatg gcttggtcag ccactgctaa ttcattttct ttcaagcctt
    15481 tttgtggtcc gaaaacaaaa gaagcgcctt cttttccgca taaaagatta gtaacatcag
    15541 taatgacagt gattttggct ttaatcagct caataggcac gttcgtttta tcaactgtag
    15601 caattttacc tagattttct cccagtgctt ctactttttg attatcttga tcgtaaaaag
    15661 cataacctag accttctgcc atgccgatgc cgccatcgtt ggtactactt ccgccaacgc
    15721 cgatgatgat gtgtcgaaca ccttgttgca acaattgtcg tatcagttct cctactcctc
    15781 gcgtggataa cctaagtggc tgttgttggt ttagtgggac atctttcaat ccgacgattt
    15841 ctgccatttc aaaaatcgca gtttgaccgt ctgaagcgta ctggatttct ttgtttttgc
    15901 caaatgcatt agtaacgact gctgtttgcc gcttcaacct taaactgtct gctaatgatg
    15961 aaaccgttcc ttctcctcca tcgcctatag gtagcagatc atattcagcc tgaacaaaaa
    16021 cttcttgaaa acctgattga atggcttgtg ctgcctctaa ggctgtcaga ctttctttga
    16081 aagaatctgg cgcaatcaga atacgcatta ttttcccctc cgttccaaga tcagttcttt
    16141 ttccagctgg tattggtctc cattgacaaa aataggtaat gtttctttcg tctctttttt
    16201 tattactatt tgtttttttg tcaaaacaaa tagcaacctg tgatttttcc aaataaaagg
    16261 aaaagaaatt ttttcccatg ctgaaggaag tcttggagaa atagaaagag ttccattcgt
    16321 tactgtaata cctgaaaaac caaatataac tgctagccat agtgctccta atgaagcagc
    16381 atgaattccg tcatctgatg aatgcggatc tggtcctaaa tcaatcaggc acgcttcttg
    16441 gaataaatga tacgcccatt ccatttcttg gatacggcaa gcctctatgg cgtgaatcgc
    16501 tttactcaac gatgagtcgt ggattgtttt gttttcatag taatgcaaat tcttagaaac
    16561 gattggttga gaaaaatact caggtaataa gtataacagc atgacaagat ctgcttgctt
    16621 gctgacttgg agttcattta cttcgctacg ggcataatca agtaaaatag actggctgcc
    16681 aggacgttct ttgtaagtgg tcaaatcaat aactggctta ctgagatacg tgtcatcttg
    16741 cggaatcagc tgttctttgt taggcactgg caaatataac ttatctaaaa aattttgaca
    16801 ttctttcaaa aaaagcggat cgccagcttg atatttaaca gctaaggcca cattataatg
    16861 cgccagatag ttcgtatatg cattattgtc gatatattct gtgtattcat ctggaccaat
    16921 gactctgtgt atctctaaat gatcatcgac ttttacagct ctgctcagcc aaaaagctgc
    16981 tgtttcatga atgagcgttt ttccctttgt ttctaaaaac gattgatcct ctgttgcttg
    17041 gacatactct tgaacggcat aagcaaggtc tgcactgata tgatgttctg cggcagctga
    17101 agcaacttct tgtcttgttc cggttttgat attcaatgca gcaaatttgg gtgtctcttc
    17161 ctgaccagtg tgtgcgcttt cccatgggaa aagtgcacct tgatagtgat aatctcttgc
    17221 tttttgccgt gcgccttcta atcgatcata acggtacagc agcaaattct ttgctacttc
    17281 aggaaactga tataaaaaga aaggcaggat aaaaatttcc gtatcccaga aaacatgccc
    17341 tttataacct tcgccagtta gtcccttcgc ccctacacta acacttggat cattgcgggg
    17401 agtcataatc tgtaaatggt aagcagcgaa gtccatcgct aactgatcga aagaagaatc
    17461 gccttggatc gttatccgat gctgatgcca aaaatctgtc caataagaca tcgactgctc
    17521 taaaatttct gtataactaa cgcttttctg ggcttgggca atacttttct taaacgggtc
    17581 tgtttgctga agagaggtag agagcacgat gatcttctcc agcgtaaagg acgtattttt
    17641 tctgatcttt tctgaaaagg aagcggtgat ccggcgattt tttgcttgga atacacctgc
    17701 tttattgaat ttagctgcaa tcccaatatc aattttactt tctgttgtct ggtaggatgc
    17761 actgatcaaa tcgtcaccaa atactcgcag ttctttttca accaactgct gtgtaccaaa
    17821 attggtttgc tgtccatcga tacccgtttt cacatctact tggcagtctt cggtcaacgg
    17881 cttgatgacc actttcaggg ctgcctgatg gagattattt tgatcagcaa cacgacaagt
    17941 aatgacttcc actttttttc cttgagcagt ttcaatgagc gcatagcgtt taagctctcc
    18001 catttctaaa tctagtgccc gctcgtatgc aagaactttc atcgtctcaa gagaaaaatg
    18061 ttcaccgtcg atttttattt cccatctgat gacatctggg agattcacta actcggctga
    18121 ttctgctcct aaaggtcggt tatatacacc agctgcaaac attcccctta cttgattccg
    18181 atagtcttcc tcctggcttc ctctgatacc aaaaaatcca tttccaatgg tcatctgact
    18241 cgcatactta ttgatatact ctaaatcaaa ctgtttttct tctactttca taaggtaata
    18301 acttctcctg tttctgccga acgatataaa ttttccacca gattctggat gacatatcct
    18361 tgccagccat ctgcaatcat ctgagtctgg tcaccgagcg cccgattcac aaaatgagcc
    18421 atacttagtt catgtgggtc attaactggc gtggtctttt gtaaggaaac cagctttcca
    18481 tctacatctt cgaatagttc gcctggatac agattagcac ctgcctgatc gccacaaaaa
    18541 gccacattca gtttgtcttc tctgatattc aaagcaaacg aagtattcag ttggatgatc
    18601 ttgccgtttt ctaattccag tgtgccaaaa attgcatctt ctactgtgaa tttgcttgga
    18661 tcccatttcc cgaatttccc tgaatttttt ttcgtaccaa ttttttggaa gctgtacgcc
    18721 cgaacgcttt ttactttagg aaatccagta atatacatcg ctgtatcaag catgtgaatg
    18781 ccataatcga tcaaaggccc gcctccttga agttctttgt cgataaacgt tccccagcct
    18841 ggaacaccag accgacgaag cgcattcgct tctacgtaat aaatatcccc gagaacatca
    18901 agatgattct tgatcattgt tgcttcgtca gaaaaacgat gctggaatcc ataagccaaa
    18961 atctgcccgt ttttatcggc tgtctctgcc atctttcttg cttgatcagc tgtcatagct
    19021 ggtggtttct cgcacatcac tgaagcatta gcttcgaggg cagccaatac atgttcgaag
    19081 tgaaagcgat tgggtgtaca gacactcacg atatcgggag aaatctcatt cagcatttgt
    19141 gtaactgatg tatacgcatg agaaaatcct gtacgtcggc aaaagtcttc tgctcgctgg
    19201 ctgactggat caaccacagc ggccaattct aagacatctg atcttttttg ataataagca
    19261 gcatgtactt tttctgctac ttgtccagcg cctatgattg ctactttctt catttatttc
    19321 tccctccttt gcttatttac ttattgttat tctttctcta ttctttctct aaatcattta
    19381 aatgacgcgc tgtttccaga cagtttttca agtattgcaa tgattcctga taaattttca
    19441 cttcattttc tcctcgcaaa cgacattcat ataccatata accttcatac tcattttgaa
    19501 gtagcgtttg aaaatggcga gtaaaatcaa ttgcgccaga tcctggttgg tagcgatgat
    19561 tatctgctaa atggatatga cccacatact ctttttgcgt agtcaatgct tttgaaatat
    19621 catcttcttc aatattcata tgataaaaat cagcgatgat ctgcacatgt ttcaattgat
    19681 tagagtcaat gtaatgacgc gcatccgcta acaaattgat catatggtct tggtatcggt
    19741 tcaaaggctc caaataaata accgtacctg tttcttcggc tactttatct aaataacgaa
    19801 gtgattcgct gactgcttta tagtctcctt ctttgcttcg gggtgaaacc atcggcggta
    19861 atcgataagt gaacattccc caagctgctg ggataacgat tcctttgcct ccaacctcgc
    19921 ttagtgcacg caaaatctca gcaatttgac gtacaccatt aagacgccgt tcttcgataa
    19981 agtcaccgat ccacccatcg tagccgttac aagctgtcac tactgggatc cctgtttctt
    20041 tgattgcctg tttgactgtg tcgatatttt ctattaacaa cttaccgtcg atttcgtatt
    20101 cttcaaatcc acagtctttg ataaatctaa atttttctaa aatgtctctt gggaaaaatg
    20161 cttgatcttg cgtaccgaat ttcattgttc tcctcctcgg acttgaacgc ccattttgat
    20221 actttcttct gggtgctggt ctacataacg catgtaagct tctgcgcttt ctgcaaatgg
    20281 cacaactgga tcaatgattt cttcacaatc caagtaaccg ttcatcaata attcccaaca
    20341 tgtgtcctcg attcgtttac ggttccatct tgggtaatct gggtttggtt cactagatgc
    20401 tcgagcaaag acgatttttg cattattgaa atgtgcttcg cgaccaagat taaacccagc
    20461 tggaaaaggt ttagcaaagg caacataaga aatgatcccg ccatagccga tccctcttaa
    20521 agaagcttgt aatgcggcag cactgccact cgtttcaata actgaatcta ctccacgttt
    20581 atctgtcaat tcctttagac gaaaaccgac atctgctttc ataggatcta gcgtgtaatc
    20641 ggcaccgtat ttttctgcta attctctacg ctgcgctatg ggatcgatcc caacgatggt
    20701 agtagcacct gcttttttag ctaattgaat cgcaatttgc ccgatagcgc ctaaaccgaa
    20761 gattgctaca gcatcacctg ctcgaacatg tgcttcccgg ataccaccta aagcgaattg
    20821 agcaggatcg taacatactg catttttcca ttgatccaac cgatcaagtt tacgtagttt
    20881 ataattatca acaccgtttg taatcagcgt ttcacgaatg ggtccataag tgcagactaa
    20941 ctctcctttt tgatactctg tcaccaaact gcccgtttct tcgatcgtac cgacaatcat
    21001 atttcctaat tgaaattcgc caaataccac accgcgttgg cttccttctt ctcttggcaa
    21061 gaataggcgc cattcttctg aaaattcttc atcgataaat ggacttaatc ctctaaagtc
    21121 gacaatttct gttcctggtt ttggagtagc gaaaattact cggatacgta cttcgttctt
    21181 ttcgatctca cggtcttcgt aatctttgaa tccggctatt cttggttcta atgcaactaa
    21241 ttttttcatc ttttctttcc tctttctttt ctttttatcc ttttacgccg ccttcgacta
    21301 aatcaccttt aataaatcgt tcagataacg catacataat gatgactggt aaagcggtca
    21361 ccaatgaagc ggccatcatt cgtccccaaa tgtagtctgg tgtactgaat aatgtgttca
    21421 aaccgattgg taaagtaaat ttttcggagg tcgacaggaa aatcgaagca aataaataat
    21481 cattccacga aaccataaag caataaacga agacagaaat gattccagaa atagccaatg
    21541 gtataatgat ccgaataatg atctggatcc ggctaagacc atcgatcatt gctgcttctt
    21601 caatatcagt cggaatcgtg tcaaaataac tttttagcat gaatatcgca gtaggaagtg
    21661 tttgaacgac catcgtgata atcagtgctg tattggtatc atacaaacct agaccggaaa
    21721 tgattttaaa taatggaaca acgatcaaaa taccggaaaa catataaacg gtgtaaaagc
    21781 tagcattgat tttcgagcga gctttgaagc gtagttttga caaagcgtat gccccgctga
    21841 tcccaatcac tactgcagtt acggaggcta tcaaggagat cactaaacta tttttgaaat
    21901 acatgatgaa tggaaaaatc tcagcattga aaatatcctg ataatgttca aaagtccatt
    21961 ctttcggaaa aatagtttgt gtcgttgcaa ttgcttcttg tgaatccttg aatgatgtca
    22021 tcagcatgat caaaaatgga aacaaattga cagctaatag caacaaaatc gtcgcgtaaa
    22081 ataagatttt cctgctcttt ttatttttca tttcaagtcc accttctttc gtgagagcaa
    22141 gacgaccgct gcaataatga tgaacaatag aatcgatata gctgctgctt ttccaagatc
    22201 attgaacgca aaggctgtct gatacaaata aacgcctaag atattgactt tattcgtcag
    22261 tagatagaca tctgtaaaca tatagaacat ccagatagat cgtaaaacaa tcacagttgc
    22321 tagtactggt ttgattgccg gcagtgtcac gatcttgaac ttctgccaag catttgcacc
    22381 gtccatttca gctgcttcat aaagcgtttt gtcgactgtt tgcaaaatag ccaaaaatga
    22441 aataaacgca tacggatagt atctccagat agcaaacaaa acgaccataa agaagctagc
    22501 aactggctgg tcgaaccaca gcggtgcttc gttgaaaagc tgcaacctat ctactaacag
    22561 atcattgacg attccataac tattattgaa catatatttc caagcaaaaa tcaaagaaat
    22621 agatggcgta acataactta ataaaatcag tgaacgcacc gttttcctaa atctgaactt
    22681 gcggttaagc aaaatagcta cggctaatcc taaagctgta ctgcctgcta caactaagaa
    22741 tgtgtaagca actgttaaac ctaaagaacg ataaaattca ctatcactta aaatttcaag
    22801 ataattgctt aatccgataa aaacggcgtc tgagttagga ttcagcggca tatcgaaaaa
    22861 actgatctga atattggaaa gcattggaat cagcactaaa acagctaata aaagcatgct
    22921 tggtgctaaa agtcccatgg ctaattttaa gtcagaatgt ttccttggac gattcattga
    22981 aacctccccc tgataatctg ccaatagcta tctacttttt tcgaacacca ttggcagaac
    23041 ttcttgttat ttcgtatttt tttgtgcgtc agctaaagct tgatcgacat cttcgtttcc
    23101 gacagttact tggttcactg cttttccgat cacacctgag cttgtgatat ctcccatttt
    23161 cgtgaaattc ttttccccga ctagtccaaa gacttgtact tcatcaaaag cactagcaat
    23221 ctcagatggc agctcgccaa aagacttgat gacttcattt tctttgtaac catccagttc
    23281 gactacttgt ttattcactg gttgagcacc accaggagac atcaagaccc acttttccat
    23341 gtttttcggt tgagataaga aagctgtgaa tgcttcagca gcctcttttt gtttctcgtc
    23401 tagaccagaa gaaatcgtca atccagatac tgtgccatag acagcttgat ctttttgtgt
    23461 tgggatagca aaaccgatat tttctgagtt ccccgcttca taaacagaag gcaaaatgta
    23521 agttgaatag attgccattg gtgctgttcc attcatgaaa gcatctttga tttctgtcac
    23581 atcattagag cctggcatcg tgtattggga taagttttga taaaacgaca atgcttctct
    23641 catcttttcc gtatcgatcg ttacctcgcc ttcatcatcc aaaacatttg ctccatttga
    23701 caaagcaaat tgagagaacg cttgctcact cattgttcct tcagcagtag gcatagcaat
    23761 tccatattgt ttattctctt tatctgtgaa atgttgagca atttttaaaa tatcatccca
    23821 attttctggt tctgaaaaac cagcttctga taatttttct ttgtcatacc aaataccttg
    23881 aacccagccg ctaattggtg cagcaatata gctttttcca tcttctgaac gaacaaggtt
    23941 tttggctccg tcataataat tatcttctcc agcttcctcg ataacgtttt ggactgccgt
    24001 ctgatcaatc agttcatctt tatccatcac tttagcaaaa tcctgactga cttccattac
    24061 ttctggtaat ttaccggaac gagctaacgt aacgattttt gtattgaacg ctgattcttc
    24121 taccggcact tgcttgattt tgatgtctgg attttctttt tcaaaatcag caaccagttc
    24181 attgatcaca cttaatcgtt cctgttcgac agaagagtgc atgaattgaa tcgttgtctg
    24241 ttgtgattcg ttagagcttt gactttcacc acaagcagta agaagaaatc cagtagctag
    24301 cagacaggta gtaacaataa tttttttcat ttttttccac ctcttatttt attattttca
    24361 gccacatata ttcatacggc tggaatatca actttcgttc ttgactgcaa tggataattt
    24421 gtccagaaaa caggtctagg taatctcctt ttggtaaaag ataacctgct gattgattgg
    24481 aaaaattatg gataactaag actttctctt ccttcgcttc gcgaataaaa ctgataaaag
    24541 aatctgctga gtccagtaag taaatcaaac tattcggatg gaaggctttt tctttttttc
    24601 gaatagatag catctgggtc aattcaccat atactgctgt tcttaatgga tctgtctgca
    24661 actctttctc aatatctgct aacaaaaatt tttgccgatt gatttttcga ttctctcctg
    24721 ttttttctac gcctttgtaa tcatttcgac ttcccagcac actttgaata taaattgccg
    24781 gcacgcctgg taacgttacc aaaaatgaat gagcagctaa aaagcgtttg cttctccatt
    24841 ccgtcgtatc tgttggagaa cttaacgcat ctagatacgt agcgtttatc tcatatggac
    24901 tggtcgttcc atctgggttt ttcttgtagt ttactcgggt accctctttc ttcagctgtt
    24961 ccactaattc aaggatcgtt ttttccggca gaatacctcg taccggattc aatccgatac
    25021 cgtcatggga ggctaaaaaa ttaaaaaaag ttgttttttt cgatgcgaaa tcgatggttt
    25081 ttaaccattc tttcaactta cttgtattac ccgaacgaat cgcttgaagg gtcaaaggtg
    25141 gtagcgaaaa ctgatagacc atctgtgctt cattctcgcc attcccaaaa taactgatat
    25201 tatctttgtg tggcacattt gtctcagtga tcaataccgt tcctggagct gcttcatcag
    25261 cgattgcacg gaataattgg atgattttat gcgtttctgg caggtgtata caagaagttc
    25321 ctagttcttt ccataaaaat cccacagcgt ccaagcgaat aaatgaagcg cctttttcta
    25381 agtaaaacaa aagaatatcg atcattttca ataaaacttc tggattttta aaattcaagt
    25441 ctacttgatc ttcgctaaaa gtcgtccata cgtgtttttc tttcccgttt ttgtcaatga
    25501 acgttgtaag taacgggctg gtccttggtc tagtcacgct gcttgtatct gtatccagtg
    25561 gcaaatcaat aaaaaaatct ttgtacgtat cattcaagtt taaatattcc tgaaaccaag
    25621 tactttcggc agacatatga ttgcagacaa agtcgaacat taaccgtgtt tcgcttctca
    25681 tttcttctat atcttcccat gtgcccaaac ggtcgttgat tgcctgataa tttacaacgg
    25741 agaaaccatc atcagatgta tatgggaaaa atggcaagaa atgtacaact ctaaatgtat
    25801 ctgccaaata cttttgataa aatttcttaa atgtacgcaa agttggttgc tgctcttcaa
    25861 aaaattgatc cccataagta atcaagaaaa tatcttcttc gtcccaatgc agtttgcctg
    25921 cctggccttt cttctgctga taaacactga ctttttgttc aatcatagag gcggttttct
    25981 cagacaaatc tgagtcgcga taaatcgctt gtaaaagttt tgtatacatc ggattcccct
    26041 ttcttttttg ggagcgttcc caacgatttg atcatattat ggaaaacgct tactgtcaat
    26101 agcatttttt taaataattt tgatatacac aaaaatacaa ataagaaagc ttatgtatca
    26161 ataattaata gcttcttaaa aaaatatggt ctctcatgat catgcaagct attcctaaat
    26221 tttcaaaatc atagacaaaa aagaatgtct attgtactat ggaattattc taaaacgctc
    26281 ccaaaaagga ggtgcatata aaattgaaac ctactattta tgacattgcg aaaaaagcta
    26341 atgtctcaaa atcaactgtc tccagagtat taaataacca gccaaatatc tctgataaag
    26401 caaaagcaag tgtacttcaa gcaatcaaag aattgaatta tgaaccgagc aaaattgcaa
    26461 gaggactgtc aggaaatggt tttgacgcga ttctagcatt atctcatcgt acttctcata
    26521 cgacctatgg caatcctttt ttttcagatg ttattcaatc catttctgcc gtttctgaac
    26581 aaaataactt cgacttgatt ctacaaacgg caaaaacacc agaagaagag ctagaaaaat
    26641 gcgcgaaaaa gatccaagaa aaaatgatcc gaggaattat tattttaagc tctacgatgg
    26701 atgaaacact tctttttgaa ttggatcaat acaatattcc tattgtggta atcggaaaag
    26761 tcggaaacga ctacacgaac atctactcag tggacacgga taatttccag gatagttacg
    26821 atttggtgga aacactgatc aagaatggac accgtcatat cggctgtctc catgctccga
    26881 cagaagttta tgtatccaat gatcgtctca atggttaccg tcaatgctta tttgatcacc
    26941 acctagatat ccgtaatgaa tggattatag acggcggctt tcgcttagaa gatagcatgg
    27001 cagcaatgaa tgatttaatg aagctacgag aaagaccaac tgcgattttt tctaccgatg
    27061 cattaaaatc attgagtatt tacaaagtgg cagaacaatc tggaaagcag atacctgatg
    27121 atctttcgat cgcaggattc agtgatccct tattgtcctc cctattttcg ccacagttga
    27181 ctcggataga cattccgaca aatcagttag gaatcaaagc cacagaactt ttattccaac
    27241 taatccacca ccaataccct gaagaaaaaa gaatcattct ttcaaccgag attactctca
    27301 cagattcgat ccaacaacaa gaaatgtaga acagaattat aaaagaacag aaacactgag
    27361 gataagtcag ttactctgtt cttttttcaa tcactcatcc ctcgttaccc cctcccggta
    27421 ttttagcgaa tttttcttat tttccatctg ttttagatag ctgtggataa ctataatgtt
    27481 tgtgttaaac tattttttcc acagggaaga aaaaactatt tttaaccacg ttgtgtataa
    27541 gtttttatag ttcgtttttt taaacacatt tacccttatt tcaatccatg ttatttgggg
    27601 atacttatct ctaaaacata aatagaataa cagacatgtc tactggtttt gttttattcg
    27661 aggaattatt caataatagc tagcaaaata ttaaaaataa ccgctctatc ttcccatcaa
    27721 tttattttgc attcaaaaaa tgatctatct ttacttttgt tgattgactt ctcttggaag
    27781 atgatcgttc cgatacctta attggatacg aaccgatgtt gttaagatcc tttcccactt
    27841 ttcttctagt tagacaaatt attttagaca aaccaaaaaa gaggttgtga caataatttg
    27901 tcacaacctc ttttttaaaa tatctatttt gtttgattgt tcattgcgtc ttctgcagcc
    27961 atttgcgctt caatatctga aatactgtag acattttcgc ttgctacacc gacttctttt
    28021 ggttccatgt cacgataacg ttgcatacca gtaccagctg ggatgatctt acctataata
    28081 acattttctt tcaaaccaag aagaggatct ttcttaccgc ggatcgcagc atccgtcaag
    28141 acacgagttg tttcttggaa tgatgcagca gataagaaac tatttgtttc taatgatgct
    28201 tttgtgatac ctagtaagac aggtcgagaa gttgcaggaa cgcctcctga gactagcgta
    28261 ttgtagtttt gatctttaaa gtctgcgatg tctaataatg tacctggtaa gatatctgta
    28321 tcacctggat ccattacacg aactttacgc agcatttgac gaaccattac ttcgatatgc
    28381 ttgtcgccga tttctacccc ttgcatacgg taaacacgtt gtacttcacg aagcaagtag
    28441 ttttcaacag ataatacatc gcgaacttgc aacaattgtt ttggatcgat tgatccttct
    28501 gtcaatggtg caccacggtg gatcatatcg ccttctgcta ctttcatacg tgctgtataa
    28561 ggaacagtat acgtacgtgt atctgttttt cctttgattg ttacttcttt ggtacgtgtt
    28621 gcaggatctt ctgagatatc gatgacatcc cctgttactt ctgtgatcac tgcttgccct
    28681 ttcggattac gtgcttcaaa gatttcttgg acacgaggaa gaccttgagt gatatcgtct
    28741 ccggcaaccc cacctgtatg gaatgtacgc atcgtcaact gagtaccagg ttcaccgatt
    28801 gattgagcgg cgatcgtacc aactgcttct ccgacttcaa cgtcagagcc agttgcaagg
    28861 ttgcgtccgt aacaatgttt gcagacacca tgttttgtat tacatgtgaa gacagaacgg
    28921 attgtcactg tttcgacacc tgcatcaacg atttgttttg cgatgtcttc ggaaatcaat
    28981 tggtttcctg caatgatcaa ttcatttgtt tcaggatgac gtacttcttt acgggtgtaa
    29041 cgtcccacta aacgatcttc taatgattcg atgatttcat ttccctcgcg gatggcttgg
    29101 atttcaagac ctcggtcagt accgcaatct tcttcacgga tgattacatc ttgggccacg
    29161 tcaaccagac gacgagtcaa gtaacctgaa tcggcagtct tcaaggctgt atcggtcatc
    29221 cctttacgag ccccgtgagt tgagataaac atttccaaga cggatagtcc ttcacggaag
    29281 ttcgaaatga ttggcaattc catgattcga ccattaggag cggccatcaa accacgcatt
    29341 ccggcaagct gtgtaaagtt ggaaatgtta ccacgagctc cagaatcaga catcatgaag
    29401 attggatttt tcgcttccaa accttccatc agtttttgtt ggatgctgtc ttttgcagca
    29461 ttccaaacag caatgacacg ttcataacgt tcgtcatctg tgatcagacc acgacggaat
    29521 tgttttgtaa tagtttcaac ttgtttatgg gcattttcaa tgatttcttg tttttcattc
    29581 agtacactga tgtcagcgat ccctactgtg ataccggcat gtgtcgaatg tttgtaccct
    29641 aagtctttca tacggtcaag catcttagaa gtttctgtta ctttgaatcg tttgaagact
    29701 tctgcgatga tgtttcctaa gtttttcttc ttgaacggta atactaattc ttgctctttg
    29761 atatgtgcag gaatatcagt accagcttca acaaagtatt tgtccggtgt ttggacggtc
    29821 aagttgaagt ctgttggttc attcagataa gggaattcag gaggcatgat ctcgttgaag
    29881 atgatcttac caactgttgt gatcatcgta cgttcttttt gccattcagt aaatggtttt
    29941 tcacctaatg agttagggtt cacaccgata cgtgaatgta aatgaacata tccgttgcgc
    30001 catgcgataa cggcttcgtt ttgatctctg aagaccattc cttcgccttc gcgtccttct
    30061 tcttccattg tcaagtagta gttacctaga accatatctt gggaaggagt aacaactggt
    30121 ttaccatctt tagggttcaa gatgttttga gcagctaaca tcaatatacg tgcttctgct
    30181 tgtgcttctt cattcaatgg aacgtggaca gccatttggt ctccatcgaa atcggcatta
    30241 taagcttcac atacaagtgg atgcaaacgg attgcgcgtc cttgtactaa aactggttcg
    30301 aatgcttgga taccaagtcg gtgaagcgta ggtgcccggt tcagcaatac tgggtgttcc
    30361 ttgattacgt cttctaaaac atcccatact tcgtcttctt gacgttcgat tttacgtttc
    30421 gcatttttga tgtttgaagc tagttcgcgt tgaacaagct cacgcatcac gaatggtttg
    30481 aataattcaa tggccatttc ttttggaagt ccacattggt acatcttcaa gaaaggtcca
    30541 acaacgataa cggaacgacc tgagtagtcg acacgtttac ctagcaagtt ttgacggaaa
    30601 cgaccttgtt tccctttcaa catatgagaa agagatttca atgggcggtt acctggtcca
    30661 gtaactggac gtccgcgacg accgttatcg atcaatgcat ctactgcttc ttgcagcata
    30721 cgtttttcat tttgaacgat gattccaggt gcattcaagt ctaacaaacg tttcaaacgg
    30781 ttattacggt tgattacacg acggtaaaga tcattcaagt cacttgttgc aaaacgtcca
    30841 ccttctaatt gaaccattgg gcgtaaatct ggtggaataa cagggataac gtccataacc
    30901 atccagcttg gttgatttcc tgaagcgcgg aatgcttcta aaatatccaa acggcggatt
    30961 gcacgtgtac gtttttgtcc ttgtgcagat ttcaattctt ctttcaattc ggctgcttct
    31021 gcatctagat caacattatc aagtaattgt ttaatcgctt ctgcacccat agcagcttgg
    31081 aattcttgtc catattgttc acgtttttcg cgatattcgc gttctgtcaa caattgtttt
    31141 ttctctaaat tcgtatttcc tggttcgatg actacatatg aagcaaaata aatgatttct
    31201 tccaaagcgc gtgggctcat gtctaataca agacccatac gtgaaggaat ccctttaaag
    31261 taccagatat gtgaaacagg agctgctaat tcaatatgtc ccatgcgttc acggcgaact
    31321 ttcgaacgag taacttccac tccgcatcga tcacaaacga ttcctttata acggatacgt
    31381 ttgtattttc cgcaggcaca ttcccagtct tttgtaggac caaaaatccg ctcacagaac
    31441 aacccttcgc gttcaggttt taaggtacga tagttaatcg tctcaggttt ttttacttca
    31501 ccgtaagacc agcttctgat tttttcggga gaagccaaac ctatttgcat actttcgaat
    31561 ttatttacat cgatcaaaag gggttccctc catttcattt aatggcaaac cgcaagacgg
    31621 ctgatcttcg accgccttgc agctcataga ccggattagt ctaaattatc ttctgcggtt
    31681 tcaaagtttt ggatgacatc gtctttttca tcttccactt gttcagcagc tttcttttct
    31741 aattctttgg cagtttgctg ttcggcaaat tttgtcaaag catcaacagt gatcaaatcg
    31801 tcgtcttcat cgtccatgtc gcgaagttcg atctctgttt cttcgatatc caagacacgc
    31861 atgtccagac ctagtgattg caattctttc accaatacgc ggaatgattc cggtacacct
    31921 ggttttggaa ttggttcacc cttgacgatt gcttcgtatg ttttcacacg tccgactacg
    31981 tcatctgatt tgtatgtcaa gatttcttgt aaagtataag ccgcaccgta agcttccagt
    32041 gcccatactt ccatttcacc aaaacgttgt ccaccaaatt gagctttacc tcccaatggt
    32101 tgttgtgtaa ccaatgagta aggtccgatt gaacgtgcat gcaatttgtc atcgaccatg
    32161 tgagcaagtt tgatcatgta catcacaccg acagacacac gtccatcaaa tggttcacct
    32221 gtacgtccgt cgtacagaac agttttcgca tcgctggcca taccggcttc acgaactgtt
    32281 tcccatacgt cttcatcact tgcaccatca aatactggcg ttgctacgtg gatacctaac
    32341 tgacgtgcag ccatacccaa gtgtaattcc aatacttgcc cgatgttcat acgtgaaggc
    32401 acccctaaag gattcagcat gatatcgatt ggtgttccat caggtaggaa tggcatatct
    32461 tcttccggca taatacggga tacaacccct ttatttccgt gacgaccggc cattttatcc
    32521 ccttcatgga ttttacgttt ttgaacgata taaacacgaa ctaacatgtt tacgcctggt
    32581 gacaattcat ctccagcttc acgagtaaag attttcacat cgtgaacgat accgccgccg
    32641 ccatgtggta cacgtaatga tgtatcgcgg acttcacgag ctttttcgcc aaagatcgca
    32701 tgcaatagac gttcttctgc agataattct gttacccctt ttggcgtgac tttccctaca
    32761 agcaaatcgc catcttggac ttctgcacca atacggatga tacccatttc gtctaaatct
    32821 tttaatgcgt cttccccgac attagggatt tcgcgtgtga tttcttcagg tcctaatttt
    32881 gtatcgcggg cttctgattc atattcttca atatggatag aagtgtatac gtcatctttt
    32941 accaaacgac ggctcatgat gatcgcatct tcatagttgt acccttccca agtcatgaaa
    33001 ccaactaaaa cgttttggcc tagagccatt tcgccttgtt ccatagatgg tccgtctgcc
    33061 agagtatccc ctttttcgac tttctcaccc aaatgaacga ttggacgttg gttgtagctt
    33121 gttccggagt ttgaacgacg gaattttgtt acatcgtatt tatctaatgc accgttgtcg
    33181 cggcgtacgc ggatttcaga agcatcaacg tattcaacga caccgtcatg tttacataac
    33241 aaagcagctc ctgagtcatg cgctgatttg tattccatac cagtaccaac ccatggtgct
    33301 tgaggattga tcaacggcac tgcttgacgc tgcatgttgg cacccatcaa ggcacggttg
    33361 gagtcatcgt tttccaagaa aggaatacat gctgtcgcaa cggcaactac ttgtttaggt
    33421 gatacgtcca tgtagtctac tttatcaata gatacttcta agttttcact ttgagcacga
    33481 gccataacaa cgtcttgagc aaatgttcca tcttcattca atgggctgtt tgcttgggct
    33541 acgatgtaat ggtcttcgat atcagctgtc aagtagtcga tttggtcagt aacacgacct
    33601 gtttcacggt ctacacgacg ataaggtgtt tcgataaatc cgaatttatt tactttcgca
    33661 taactggaca aactattgat caacccgatg tttgggcctt caggagtttc gatcggacac
    33721 atacggccat agtgggagta gtgaacgtca cgaacttcat aaccggcgcg gtcacgagtc
    33781 aatccgccag gtcctaaggc tgaaagacga cgtttgtgtg tcaattcgcc aagagggttt
    33841 gtttgatcca tgaactgtga caactgagaa gaaccaaaga attctttgat acttgccaca
    33901 actggacgga tattgatcaa ttgttgaggt gtcaatgttt cagtatcttg gatcgacatt
    33961 ctttcacgaa ccacacgttc catacgtgct agcccgatac ggaattggtt ttgtaaaagt
    34021 tcaccgactg aacggatacg acgatttcct aagtggtcga tatcatcgac attgccgata
    34081 ccttccatca agttcaagaa atagctcatt gaagcaatga tgtcggctgg acgaaccgtt
    34141 tttacagctg cttctggata gccgtttccg atcacgttta cttcacgttc agggtctctt
    34201 ggtgaaaata ctttgatgac ttggacagtc attggatctg tgaccacacc gtcttctgat
    34261 ggatagtaag tcactgaatt taggccatta tcaatgaaag gagctagtgt ttccatgact
    34321 tggtgagtca gaactgttcc tttttcaacg atgatctcgc ctgtttctgg atcaactaat
    34381 gtttcagcta atgtcagatt caatagacgt gttttcaaat ctaatttttt gtttactttg
    34441 taacgaccaa cgtttgctaa gtcgtaacgt tttggatcga agaaacgagc attcagcaag
    34501 ttacgtgagc tgtctgctgt ttttggttcg cctggacgca aacgttcgta aacgtctttc
    34561 aaaccttctt ctgttcttga gtcgcttgcg tttttatgca agtctttttc gactgtattg
    34621 cgtaatgttt cgctgtcgcc gaagatttca aagatcgtat catcggaacc aaatcctaac
    34681 gcacgaacta atacggttaa aggaatctta cgtgtacggt cgatacgtac ataagagatg
    34741 tcttttgcat cagtttccat ttctagccaa gctccacggt tagggataac agtagaaccg
    34801 aatccttctt ttccgttttt gtcgactttt ccatggaaat agacacctgg tgaacggact
    34861 aactgagaaa cgattactcg ctctgccccg ttgatgatga atgttccttg ttctgtcatt
    34921 aatgggaaat caccgaagaa tacttcttgt gctttgattt cgccagtctc gcggtttgtc
    34981 aaacgcaatg ttacatgtaa tggtgcagag tagtttgcat catgcgcacg agcttctgct
    35041 actgtatact ttggttcttt caattcataa tctacaaatt ccaaagatag attgccattg
    35101 aagtcatcga ttggcaaaat gtcttcaaac atttctctaa gtccctcatc taagaaccat
    35161 tggtaagagt ctgtttgaat ttcgatcaaa tttggtaatt ccaacacttc actgattctt
    35221 gcgaaacttc tacgttcgcg atgttttccg tattttacta cgtgtccagc caagctcttc
    35281 acccctctaa aatgtcattc aaaaagacta cccgatcaat tgttacaata atatttcaaa
    35341 tattattttt aggtaacaac agacattttt tgcggctttt aggcaaaaaa aaaccaaaaa
    35401 tagaacattc tcttgaaacc ttacttcgtg agcttctact tttgtttcct tatattaaag
    35461 ccgaaacgga caatatttcg tttctgcctt ttcttcatca gatagttttt gcaacttcat
    35521 atactacact tattttctat aaaagtcaac acttcctggc gtttcttctg ctttttcgca
    35581 acattttctt aatgttttca attttatgtt ttcaattatc tgacaattct taattgacag
    35641 acctttttat ctcggttata ctttagaaaa ttcattttgt ggaggaactt ctatgcgaac
    35701 caacatcaac caaatcgcac caacacaact gaataacttt tactttagct actttagata
    35761 ggtttgtatt catcatgatg gatacaaacg ttaaacgaca gtttgtatct atgatggcta
    35821 aagaactttg tattgcagca aaaagccacg tagacaaaat gctaagtggc tgagcagtga
    35881 aaatacaaag taaaagtatc aagcattcta ctttttcaat ttattttccg acttttcaat
    35941 ccatttggac attttgtctg aatggatttt ttgtttccca aaattaagga ggaaaaagaa
    36001 atgaaaaaaa atataatcat cggattaggc gctgccctgc tactagcttt aggaggttgc
    36061 gcacaaaaag acaattccgc agaggcatca gatggacaaa aaacaattgg cgtattgcaa
    36121 cttgtacaac ataactcgtt agatgctgcc tataaaggat tcaaagaagg attagcagaa
    36181 gaagggtata aagaaggcga taatctaaca atcgattatc aaaatgccca aaacaatcaa
    36241 gacaacctga aaagtatgag tgagaaactc gtcaaagaag atcctgattt gctacttgga
    36301 atcgccactc cagcagcaca atctttatta aatgaaacaa ccactatccc gatgactgtc
    36361 acagcggtca cagacttgga acaagcccat ttagtcacat ccaatgaaaa acctggcggc
    36421 aatgtgactg gcacgacaga tatggtgcca atcgaaaaac aaatcggctt actgttaaat
    36481 atcgtgccag acgccaaaac aatcggcatc atgtataaca acggtgaagc aaactctaag
    36541 atccaagctg atttggcaga aaaagaattg aaaaaagcgg gcgtcaaagt caaagtactg
    36601 acagcaaatt ccacaaatga tgtccaacaa gtgacgaaaa gtctagctaa agatgtagat
    36661 ggaatctata ttcctactga taacacgttc gcaagtgcgg caagtgttgt cggtgaagtc
    36721 gcaaaagaaa caaaaacacc tgtcgttgct ggcgcagttg atcaagtcaa agacggcggt
    36781 ctagcaacag taggaatcga ctacgaaagc ttgggtaaac aaacagggat catggcagca
    36841 aaaatcttag acggcaagaa tccaagtgaa cttcctgtcg aaacagcgaa tgatttggaa
    36901 ctgtatgtca ataaagacat ggccaaagca ttaggcatca atccagacag catcaaagaa
    36961 gctgaataaa acacaggagg attctcatga caaatttgct ctctcttttc ttatcatctg
    37021 catcgcaagg ggtcttatgg gccctacttg cgattggtgt atacgtcact ttccgtatct
    37081 tggacattgc cgacttgact gctgaaggaa gctttccttt aggtgcaggg atcgcggcag
    37141 taagtattac aaatggctat catccattga cagcttgtct tctaggcttt ttagggggtg
    37201 cggcagcagg gcttgtttcc ggactgcttc acacaaaatt gaaaattccc gcccttcttg
    37261 cagggatcat caccatgact ggtttatatt ctgtcacatc ccgtgtgatg ggtgcgccga
    37321 acatctcttt attgggtcag ccaacgatct ttcattgggt cgagtcattc ggcataacaa
    37381 aagacaacgc tgtactgatc gtcggtctgc tttttgcttt gatcgttgta tgtttacttg
    37441 ttttgttctt acgtacagaa acaggacttg ctattcgtgc aactggcgat aatctggcaa
    37501 tgagcgaagc aaacgggatc aacacagata atatgaagat catcggttat atgatttcta
    37561 atggatgcat tgctctttct ggctccttgc ttgcgcaaaa caacggcttt gctgatttaa
    37621 attctggtat tggaacgatc gtaattggac ttgcttctat tatcatcgca gaagttttgt
    37681 tacgtaacca gccactattt ctccgtctct tgactgtcgt tttaggtgcg gtcatttatc
    37741 gttttatttt agcgttagtc ttcgaactga atgttgaacc aagtgattcg aaacttgctt
    37801 ctgctttcgt gctagtgatc tgtctttctt tcccgcagat ccagcaaaaa ttccatttac
    37861 ctcaaaaaaa gaaaggcggt agtgtcaaat gaatgacgtc ttaacattgg aaaatctcca
    37921 tcataccttt gaaaaaggaa cgatcaacga aaatcatgtc ctgaaaggca ttaatctttc
    37981 cttagatccc ggcgacttcg tgacgatcat cggtggaaat ggggctggta aatctacttt
    38041 gctgaacagc atcgccggta cattttctgt cgatcagggt caaattttat tgaatggaaa
    38101 aaatatcacg aaaaaatctg ttgtcgaacg ttcgaaatcc atcagtcgcg tattccaaga
    38161 tcctaaacta gggacagccg ttcgtttaac ggtagaagaa aatcttgctc ttgctatgaa
    38221 acgaggaaaa aaacgcggct tcttccgtgg tgtcaaacca caagaccgaa catttttcaa
    38281 agaccagctg gttcggctaa atttggggtt ggaaaatcgt ttatcctcag aaatcggttt
    38341 gctgtctgga ggacaacgtc aagctattac gttattgatg gccacattac agcgtccaga
    38401 actgatctta ttagatgaac acactgcagc gcttgaccct gctacttcca aaacggtgat
    38461 ggaattgaca gaaaagctga tcactgagca gaatctcact gcttttatgg tcactcatga
    38521 catggaagac gcgatccgct atgggagtcg actgatcatg ctgcatcaag gaaggatcgt
    38581 cgtagatatc cagcaagagg aaaaacagca gctcacagtg ccccaattat tagcgttgtt
    38641 caaacaaaac agcggcacgg cattaaaaga cgatcaagta cttttatctt cataatcaga
    38701 aagaggatgg gacaaaaaat gaacgcccac cctcttcttt tttctctttc cttctttcgt
    38761 ttttgcttta tgtatcaacc gttgtttctt cgaaaactat tttgttctct ccttcttcct
    38821 gatagaatgg atgggaaagg agcttgatgc catgacaacg aaagacaagg tacttcaatt
    38881 attgaaaaag acaccagatt ttctttccgg agaaaagttg gcacagcaac tggaagtttc
    38941 ccggacaagt atttggaaag ccatcaaaga attggaaaag gcaggctatc gttttgagca
    39001 cgggcctaca gggtatcgtt acctgccctc tgacgtacta gatgcaaaag aaatccagca
    39061 agagctacgg tcgtttattc ctgatttgaa agtacaaacg atgttgactt ctgaatctac
    39121 gatgaaagat gtcaaactgg cagcagctca aggagattct gtttcgaagt tatttgttgc
    39181 tgatacacaa gaacaagctc gtggacgttt tggacggcct tttttcgctg aacctggacg
    39241 aggaatctac atgagtctct tgctccatcc agacaaacgg tttgatgaat tgcctcaata
    39301 tacgatcatc gcagccagtg cctgtgtgaa agccattgaa tctgtaaccg gtcgttctgc
    39361 ttcgatcaaa tgggtcaatg atatctacat ggatggaaaa aaagtctgtg ggattttatc
    39421 tgaagcagtc agtgatatgg aaagcggcag gatcagtcat atcatcattg ggatcgggct
    39481 taatttttct gttcctcaaa atcattttcc agctgatctc caagaaaaag ccatctctgt
    39541 ctttcccgac ggacaagcta gtgtcacaag gaatcagcta atcagcaaaa tctggcaaga
    39601 attgttcact tatctttctc acccagaaaa agcgttggac ttctataaag aaaaatcatt
    39661 cgtattggga aaaaccgtgt cgttcaatca aaaaggaacg acttatgtcg gtcttgcaaa
    39721 agaaatcggt gatcatggcg aactgatcgt ccaaacaaat gaacagaaga tgagtttgtc
    39781 ttctggcgaa atcagtctca catctatccg tacgcaataa ttatcagatt tcacaaaagg
    39841 acacctgatc tcatacagtg tccttttttc tgaattctct tcaaaagact ctccttattc
    39901 tatcagctga cagtttctct atcctctaga aaaaggtatt ctaaaaatat ctataaagca
    39961 tggtacactt tctttaaatg aatcaatgca aaaaacaaga gagtcatcag tttacacgat
    40021 caaaagagat agcaggccgc ttcctttttc aatcttatag atagaccatg ggtaacgata
    40081 aaaacaaaaa agaacttgcg acttattttg ccgtaagttc ttttttagct agtgccttaa
    40141 tctcttaatc ccaacaaacg tctcgcatag atcacctgac cagagtgcat agcagcatca
    40201 tcaataatag aaacgagacg cattcctcgt gtgactggtg gtgtccagtt ctcgtcaatt
    40261 acttcatcta gctcggaagg ttccagcctt cttaagtaag aaatagcaaa atcagcagct
    40321 cctcgcaagt atcctagcag atcttctatt tgattagctt ggatctgctt tgcttgttcc
    40381 agactatgct tccaatcttg ttcgttatct gctatcgtca tcggaaaccg gctttcccag
    40441 tcttgactat gccaaattgg agaagttcct gctaaatcag caatctggaa atctaattct
    40501 cgagcggtat gccaagccag ccaagtcatt gatttgatct gcggggctct atcttccact
    40561 ggaaaacgat tggcctcctc aatagagacg ccttcaaaca aacgttcaaa ccgatcgtat
    40621 gcccgatcca cactctcgca tagcatatct aaataatcca tttattttcc tcctttttat
    40681 ttatcctact tactttttcc taattctagg atacctactt atatgttact acacaccctt
    40741 attttttaca ctttaacagt caccatcatc aatagtttgg agattgaaag aaaaagatag
    40801 tgtcgaacta tcaattgaac aagaagcaac aatatgaacg tttcattaat attctttaaa
    40861 taaacaatga tttttcaaac gaacagttta agactaggag aaaaagagta taataggaaa
    40921 atgtttgaaa ggaaaggaag gggaaaaatg aaaaaaaggg caagtttact agtcctagtt
    40981 gctttgttgt tcaatatctt ttcgtatggt gtggccgttt cagcggaaac atacattcct
    41041 aaagaccctg ggaatattta taatgatcta actggtaact atggcttgtt aggaattgct
    41101 agtcaattcc acgtatttgc taaaaataag acaactgtga atgcacatac agacggaaat
    41161 atagcaacac atgaacttga tgcaaaaaat aattttggta cagagcttca tgaaggttta
    41221 ttgaaccaag aaataaatta tatacaaaaa actgattctt tcgctaattc ttcaggcata
    41281 cctacaggta gcacaagaat gaataaattt gtcgttggca gtaacgtgga tgtagcactt
    41341 caagatggtc atcctacagt caatggatcc aggcttgatc acttaactcc agatgatttt
    41401 tataaagatc gtgctgggca tgaatatatt gatttcgagc aggaatttgc taaattgaat
    41461 gtagcagcaa atgatcttgc aacgatcact ccagctaaaa catatactgc tgcagatttt
    41521 ccagacatga acaatcggac aatcgattta actgatttat cagataccgg gtttttattg
    41581 gtaaatatcg atgcagaagt gttaacgatg aatacgccac ttcaaatcat taatccaaat
    41641 gatcaagtag ttgtatttaa tgtcatcaac agttcttctg cattgaacgt acagtcacca
    41701 atcaaataca atgatcgttc aaatcatgaa acagaagatt tttcggatgc gaatatctct
    41761 tggaattttg gaaatgagat gactgatttg acaatcagtg ctccttttca aggaacaatc
    41821 cttgcgccta atgctactat ccgcattact caaaaccaag acggaacgat tataggaaca
    41881 aatgtgattt tagatgcagc taccaatcgt tgggatccta acgaaatatt tatcagcgac
    41941 aatggtacag atacgacaga cacaagcgac agtacagata catctaccac aagtgatagc
    42001 tcagattcat caacttcaag cgacagtaca gatactacct ctaccacaag tgatagctca
    42061 gattcatcaa cttcaagcga cagtacagat actacctcta ccacaagtga tagcacggat
    42121 acatcagctt caagcgacag tacagatact acctctacca caagtgatag cacggacaca
    42181 tcagcttcaa gtgacagtac agatactacc tctaccacaa gtgacagcac ggacacgtca
    42241 gcttcaagcg acagtacaga tactacctct accacaagtg atagcacgga cacatcagct
    42301 tcaagtgaca gtacagatac tacctctacc acaagtgata gcacggacac gtcagcttca
    42361 agcgacagta cggatacatc taccacaaca agtgatagca cggacacgtc agcttcaagt
    42421 gacagtacag atactacctc taccacaagt gatagctcag attcatctac cactacaagt
    42481 gatagcacgg acacgtcagc ttcaagtgac agtacagata catcctctac cacaagtgat
    42541 agctcagatt catcaacttc aagcgatagt acagacacgt cgtctaccac aagcgataca
    42601 cgtcatgcaa gtgtctcctt ctcaaaaaca agttcggata acaggacgaa ctttaactta
    42661 actaataaaa caagcaatga caatggaaac aaatcaaaaa gagcacttcc taaaactgga
    42721 agtcaatcga ataattggat aacactcgca ggcgttatat tacttgtaat cggtttaaga
    42781 atcactttta tgagttataa gaaatcgaaa aggtaaaaaa atattcaaga taaaaaagag
    42841 caacgtcgct aacggacgtt gctctttatt tttgcttttt atcataaata caagaactac
    42901 aattcaattt gtcaaaaaac acgtagattt ccttctgaga aatttattta cgtatcgaac
    42961 ctttccctat tcagtctttg cgatccaaaa tcagttgggt aagggaaaag agattctctt
    43021 ttgttcgaag agaggtggca ggtaatttct ttatttcctt caaagccttt tctgtgtaag
    43081 aggccgctaa cttcctagct tcttccacgc ctcctgtatg ttcaacgatt ttgcgtacgg
    43141 cgtcgacatc ttcttctgtc attgccgctt tcttctctaa ataaggtagt agctttggtt
    43201 tgtttttttg caaagagtag atcaacggta aagaatagac cccttgacgc atgtcttcta
    43261 gtacaggttt gccgatttcc tggctctctt ttgtataatc taaaatatca tcgataatct
    43321 gaaaggccat cccgatagaa agtccgatat ctcctgcttt ttttgcgaag cgctcgcttg
    43381 ttccactttc aaaagcgcca acagaacaac ttaattggaa cagttcagct gtcttacctg
    43441 aaatattttc caaatattct tttacagaaa gttcataatt atagcgatca tccatctgcc
    43501 ctaattcgcc attcaatact ttttccatac tgcgagaatt caattggaga cttttcaagg
    43561 aagtggagta atcagacaat agtttaaaac agcagacaaa taaatagtct cctgcataga
    43621 cagaaacgac attaccaaac tgactacgga tattaggctg accacgtcgc agatccgctt
    43681 catcaacgat atcatcatgg atcagtgtgg ccgtatggag catttcgata gaagctgcca
    43741 aagcgatggc tttgtctcga tcttgctctg gtccaaattg tgagaacaat agctgatagg
    43801 caggacgcaa cagctttccg ccggcatgga tcgtttcttt gattgcttgt tcgacaggtt
    43861 tgtttttcag gcggacagtt tcttccatcc gttttagtgt ttctgtcaat tctttactta
    43921 aagcaggata gttttcccac attggatgta gcttcataaa aaaactcctt gtgtgacgat
    43981 tattttttgg taaacattgg gctccatttt tgtttggttc cctgctcata atctttttgg
    44041 aatcgttgaa gtgtctgcac atgtcgtaaa agataattcg ctgcgatccc gattgcaatc
    44101 cctgataaaa tccctaaaac tgaaaggact ggcaagtaca acatgactgt ccatgattgt
    44161 gcaatgaaag aagccatcaa aagctgtccg acattatgca tgaaaccgcc ggccgcacta
    44221 attccgatga tactgacacg ttttggtcct aattgcttga ccaataacat tccaaaataa
    44281 ctaagcaaag caccactcat actataaagg aatgtggaaa tcgttccgcc tagcaaagta
    44341 gtcaggaata gtcgtagcca aagtagtaag aagctgtctc gttttttcat ggtaaaaatg
    44401 gcaacgatcg tgattagatt ggctaagcct agttttgcac caggcgcaaa agaaaaagga
    44461 taagggatca tattttccaa taaaccaatg atcactcctt gtgcaacaag tagcgaaata
    44521 taaatcattt tttgtaattt actcatggtg tgtgaaggtc taataaatca gactgtcttc
    44581 gtcacctcca tctgttgaac ggacttcgat cactaattta tgtggcaaac agacgatggt
    44641 ttcgccattt ttcgttgccc agcctcgacg tacgcagatc tggtcatcgc aatctgcttc
    44701 ttttatccgt actcgatcgc catctatctc gatcaagtta taatctccgt gttcatcttt
    44761 gtaagtatat gtgttgctct cttctccagc catcaaaggg aatgttttga tttctgtgcc
    44821 atccacacgc agtaccgctt ctttttctgc tgttgcggtg ttttgctgaa gaccaaaaat
    44881 catgactggt aaaaaagaaa gaacagtcaa aagcaaaata ataaaaacat cccaaggttt
    44941 gagcagactt ttttcagcaa attctttaag gctcattttt gttctccttt ttccagatta
    45001 actcacccaa ttttagcata aaaacaagag gttgtgacac ctgtgtcttg ctttgagtaa
    45061 taagaacgaa gaatagaaaa cagctttcca tgttttctaa ttctttgggc ttattaccga
    45121 gaagcagcag gtggaacacc gtttataaca agaggttgtg acagaagtgg gcaacttcaa
    45181 gaaataagaa ggaatttacg aaaattactt ttcaagtttt tgtgaaattt cggcttattt
    45241 ttcgaagaag ctacttctgg aacaccgttt ataacaagag gttgtaacag aggttgtgac
    45301 acctgtgtct tgctcatgga ggcttatctc gggcatctta ttcctttaat tttacataaa
    45361 aaggaggctg tgacggtttg tctcagcccc tttctattga aatcttgcat tcaaataacg
    45421 ttctttatct atttatttct tgccgtactg ggaacttggt ctaccgtacc accaattacc
    45481 tagtgtacgt tgtagccatg gaattaccca gcgatccaac ccaatcgcac gtccggaacc
    45541 gttcatcaat gcgaaagcaa caaaaatgaa ccaaatgttt acccagtaaa acatgcctga
    45601 taagcagaac gtgatcacca atacaatcgt tgtcgcactg catagccatg tgaataatcc
    45661 agcaatcaat gctaatgcca aggcaatttc aaagaatacc atgaattttt ggaagaacat
    45721 tgctacatca ttgtttggca tgatcacttg catgatcttt gtgaaccagt ctggtgactt
    45781 ctcaatcaca gccattggtt cttcaccgta tgcataactc aaaccaaaat gtgcagcttg
    45841 agtcgctgct tctccggcac ttgcccctgc tccgctggca gctgtggttg catcaccagc
    45901 agcagaagca ccactggcaa catctgttac attgtattcc catgtccaag ggaacacact
    45961 gtttccagtg aaccatgatc cttcaccaaa ccaagtactt ggtttgaaca cttcaccatt
    46021 cccaatgatt tttttggaag cttcaacgaa ccaaactaaa ccatagaaaa tacgaagtgg
    46081 cacactccat aagacattgc cgtaacgaga agaatgtcct cgagtcacgt tgcgatcatc
    46141 tttgatatgg aaaaactcat gcattaaata ttggaacata taataaccag aacgaatatc
    46201 aaagaagtat ttcaaattca cgatatgttt cattacgata gctaaaaatc cgcttaaatg
    46261 gatcttatca aataggttag ctacccccca tttggcacca atagaaacca taaatccttg
    46321 atagtttcct ttaaatttat gcttttctcc gcctttgatc gaagccacga tattcgctgc
    46381 ggctgtgtgt cctgtttgtt cagcagcttg aacgatctgc ggtgtcggtg ttcctgggaa
    46441 ttcttcataa aagactaaat caccaatgat atagatgttt ttatcttcgt agccttttgc
    46501 ctgcatatat tcattggcga tcaaccgctg tccgcgtgct gattctaatc caaagtcagc
    46561 agcgtcagaa gttcctttga caccagctgt ccaaatcagt gtgtgagtcg gaatgttgcg
    46621 tccgtctttc aatttgatat gatcagcagc cacttctacg attggtgcat tcaataataa
    46681 ttccacgttg tgcttacgca aatagcgttc agcttttgca gcatcatttc gatccaacat
    46741 attcaagatc gtcggcattg cctctacgac catcagtgtg atttcgtttg gatctaattt
    46801 ataatctttg gctaggcgat ttttccagtc gatcagttcc ccaatcattt caataccggt
    46861 aaatccagaa ccacagacaa cgaaagtcag catggcttta cgcagttcat catctggttc
    46921 caatgcagct tttgctactg tcttctcaat atgttcccga atccttacag aatcttcaaa
    46981 tgaccaaagg gtgaatccgt gtgctttgac accaggtgta ccaaagtcat tcggctctcc
    47041 gcccattcca aggatcagct gatcaaaagg ataggaacct aatttggtct tgacgatttt
    47101 tcgttcttta tcgataccga ttacagtgtc tgtgacaagt tgtacattct tttgacgagc
    47161 aaacaaatgc tgcagatcgt attggattgc ttctggttct acacgtccgc cagctacttc
    47221 atgcaactcg gtcatcatag tatggtacga atgacgatcg atcagagtaa ttgctacatc
    47281 ttcttttttc agtttctttg ccaagtattt tgtagctgaa acaccggcat atcctgctcc
    47341 tacaacgaca atattttgct ttgccattga tcatccgctc cttatagact atctatataa
    47401 tgaatatatg ataattcttt tagtttgata cttattacac aatctccata tattatatag
    47461 atgttctgtt cttttgtcta actccttttg gatttttttc aaattttaaa ataaagcgtt
    47521 ttttcacgaa atttgctgaa agaaaacgtt tgaaatatta catgggttat ttatcaaaaa
    47581 tagttgactt ataggctaaa aagattagaa tgtataatga atcacaaaga aaaattgtgg
    47641 actagaaatg gaatggtggg gtattaaaat gaagaaaaaa cgttttgtaa ctggatttgc
    47701 cgtattagca ttttcagctc tagtgttagg cgcttgcggc gcagatgaca acggaagctc
    47761 aaactcttct tctgaatcat ctacagcaca atcttcgact gcaaaaagca caacagaatc
    47821 atctgcaaaa gttgtagctg gcggagattt gcaagacggc acatataaat tagaagaaaa
    47881 aaattattca aatggttacc gtgcagtctt tgaaatggtt gtaaaagacg gcaaaatcac
    47941 tgaatcaaaa tatgataacg tcaatgaaaa cggcgaatca aaaacaaaag atgcagaata
    48001 caacaaaaac atggaagcaa aatctggcac aaacccagaa aaatacattc ctgagttgaa
    48061 tgaccaattc ttaaaagcac aaagcgcaag cggtgtggaa gtcgtaactg gagctactca
    48121 ctcatctgaa agcttccaaa actacgcaca acaattgatc caagctgctc aagctggtaa
    48181 cacagataca atcgaaatcg acaatggtgc tgatttgaaa gacggcactt acaagcttga
    48241 agaaaagaac tactctaacg gctaccgtgt gcaattcgaa atgacagttg ctggcggcaa
    48301 agtaactgaa tcaaactttg attatatcga caaagacggt aaatcaaaac aagatgatac
    48361 agaatataat gaaaatatga aagcaaaaag cggtacagaa ccaaaaactt acatccctac
    48421 tctgaacgac gaattcgtca aagcaatggg cgaagaagat ggctcacctg ctaatgtaga
    48481 agttgttaca ggtgctacac acagctcaca ttcattcatc atgtacgcac aacaattagt
    48541 gaatgcagct gaaaaaggcg acactcaaac aatcgaagta gataatatcg taacagaaaa
    48601 ataatcacat aatcatacta ataaaagttg gagggtggga cgatagccag attaggcagt
    48661 cgtctcacct ttcaaaatga agagaggaaa aagatgcgga aaaaactact attttcctta
    48721 atcacactgg gcatctcttt tatggtgcta actggctgca gcaactcagc aaataaaaca
    48781 accactgaaa gttcagcagc taccaagata ttgaaagatc catattctga tgaacagttc
    48841 ttgttaggga cttacgttcg tatccgtgtg tatgatgaag gcaaagaatc agcattgaaa
    48901 cctgccttcg atcgagtaaa agaacttggt gataaaatca cgatcaatca aaaaggttct
    48961 gagatcgatg aagtgaatga gcaagctggg atcaaaccag taaaagtttc tgatgacgtc
    49021 tacacgttag tcaagcgggc ctacgaatat agccaagatt ctcaaggcgg attcgatatg
    49081 gcgattggtg caatcacaca attatggcga atcggttttg atgacgccag aaaaccttcc
    49141 caagaagaaa tcgatcaggc attgaaatta gtggattatc ataagatcga actaaatgac
    49201 aaagaaaaaa ctgtttatct aaaagaaaaa ggaatgatca tcgatttagg tgcaatcgcc
    49261 aaaggttaca ttacggacga agtagtgaaa gtcttgaaaa aacaaggagt gaccactgcc
    49321 atcgttgact tgggcggtaa tgtctatgtc ttaggccaca gcccaagagg cgaaaaccaa
    49381 gactggacag tcggcatcca agatccgaac atggctcgcg gatctgtttt aggttctatt
    49441 aaagaacgga acaaaacatt agttacctct ggaatttacg agcgttattt agaagtagat
    49501 ggcaaaaaat accatcattt gtttgatcca aaaacgggtt atccgttcga caatgatatc
    49561 gcaagtgtca cgatcataac agataaatca attgatggtg acgggttgtc tacagcagtc
    49621 ttttcaatgg gtgtgaaaaa aggactggaa tacgtcgaaa gcgaattgaa taacgggacg
    49681 gaagcgatct tcgtgacaaa agacgataaa gtatatgtga ccgatccaat caaagacacc
    49741 ttcaaattat cggaggactc ccattacacg atgggtgacc gttctgaact aaaataagga
    49801 gtacgaacca tgacactaaa aatcttttta gaagtagttg aaatacgaac aaaggtggct
    49861 agtgtatttc cttttgcggt aggggtatta ttctctatcg ctttttttca tgagatacat
    49921 tggctaaaca cttttttatt ttttattgga atgctagttt ttgatttagc gactaccgct
    49981 atcaataatt acatggatta tgaaaaggct cattctgaag tatataagta tgaagaaaat
    50041 gtcattggcc gcagaaatct atctcctgta ttgattcgaa acatgatttt agctatgatt
    50101 gcatttgttt ttgttatcgg cgttattcta acgatcaata cgggttggct tttacttttg
    50161 atgggattta tctgttgttt tattggagta ttctatacat tcggaccgat tcctttatct
    50221 cgaatgcctt taggggaaat tttcagtggg gtgactatgg gccttggaat ttttgccatg
    50281 gtcgtttatg tcaatacatt cggttcagat gtctatgatc tgacagtcaa cttttcatct
    50341 ggacaatttg ctttggtagg aaatctttgg gctatagcag caatcgtatt agcttcctta
    50401 cccttggtgt ttacgattgc caatatcatg ttggctaata atttgcggga tcttgaccgt
    50461 gatattgaaa atcatcgcta tacactagtt ttttatatcg gacgtcctgc gggaacagtc
    50521 ttattccagc tattgatgta tgcttgctat ttcgtgattt taatggggtt gttgagcggt
    50581 atctatgaat ggccgatctt ggtcaccttc ttgaccttgc caattgtgaa gaagcatttg
    50641 gatcaattca agcaaacgtt accccagcct atcagtttca gctattccat caaaaatatg
    50701 gtcttattca atgccagtta tgtattgggg ctattactaa caatcattat gcaagccatt
    50761 taacagcatg aagaggttgt gaaaaaactg ccctgcatca agtaataaga acagccaaat
    50821 aaaaatagct ccttatattt ttcgtttggt tgggcttatt accgcagatg caagcttttg
    50881 aacaccgttt atcaggaggt tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt
    50941 tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga aactggcttt
    51001 tgaacaccgt ttatcagagg ttgtgaaaaa gtcgcttagt ttcgagtatt aagaaaaatt
    51061 ttgtgaaaat ggctttccac atttttgcat aaatttggct taataccgag aaactggctt
    51121 ttgaacaccg tttatcagag gttgtaaaat cagtgttttg tcctgagtat tagagaaaca
    51181 aatggaaaaa tagttcctca tattttgccg ttttttgagc taataccgaa ggacagctga
    51241 ttgaacacta tttgttcgga aaaagtgact aactatgaca caattttttt cacagtccct
    51301 tttttcactt gatttgattc gtaccagcga acttgacgag aactttcttg gtttggtaac
    51361 tatatggtat tcttttaaca tcctcgtttg cttcttctaa tttatttata caaagtcaca
    51421 cttttttaaa catctgttct tcgatacatt tctatttctt ttaaacatcg ataccaatat
    51481 tttgaactta agagtgcata ccaaatggat tcatttactc ttcgtcagtt acgaagataa
    51541 tcaaaatctc caacttccct acttatttcg ttttgagaat tatcgaagca atcttacata
    51601 aataactaaa aaacaaaaaa ccagaaaatc agtatactga ttttctggtt ttacatggtt
    51661 tgttcaataa aaagctgttg gaactgttaa tattaaatta tcgcatcgtt acgaattctt
    51721 ccgctcctgt tggatggatg gctactgtat tgtcaaagtc ttctttagtt gcacccatct
    51781 tgatagccac ggcaaaacct tgcagcatct catcgacacc aacaccaata gcatgtaagc
    51841 cgacgattct ttcttctttt ccgacacaga tcaatttcat ttcgcatttt tggcgataat
    51901 catttaatgc aaagtacatt ggggtaaagc gtgaacgata aactttcaat tcattttcgc
    51961 catatttttc caatgcttct tcttctgtca aaccaattgt tgcaattggt ggatgcgtaa
    52021 agacgactgt cggaacaagt ttatagtcaa gataagaatc tttctttcca ttaaataaac
    52081 gttctgataa acgtctacca gctgcgattg caacaggagt cagatctaat ttaccgatca
    52141 catcaccaac agcaaaaata tgttcatccg ttgtattttg gtatttatct actttgataa
    52201 accctttttt gtccaattcc acatttgtat tttccagacc taatttttcg gtattcggta
    52261 cacgtccacc ggcaaaaagt acacaatcac cagttaaggt ttcaccattt tcaaatagca
    52321 ccgtatattc gtcattgttt ttagtaattt ctttagcaat atgatgtgcg taagttttta
    52381 ttccagcttc ttggtacatt tggatcaaat tgtccgaaag cattttatca aacgttctaa
    52441 gtggtcgttc ttttcgatat gcccacatga cttcactacc taaaccacga aatacacctg
    52501 aaagttcagc cgcaatgtat ccagcaccta aaacgattgc tctcttaggt aactctgtta
    52561 attcaaaaaa tccatttgaa tcaattgcgt attctccacc aggaatggtc attttacttg
    52621 cacggcctcc agtagcgatc aagattttag gagcacgata ggtttcaccg tttacttcga
    52681 tcgtttgact atcgataaaa gtagcgtaac cttttatagc ctcgacatga ttgctatcta
    52741 atcctctttg ataagcaccg tgtagaaaat caatatattt ttctcgtctt tctactagac
    52801 cggcgaaatc aacatttttt aaatctgctt ggataccgta acttgaggca tctcgttcaa
    52861 ttgtttccaa aatcgtactt gcttgccaca taactttttt aggtacacaa ccgacgttga
    52921 cacatgttcc gcccaattca ttcgcttcaa tcagcaaaac ttttgcgcca tgcatccctg
    52981 ctctgtttgc tgaagcaata ccgccagagc cgccaccaat tacgatgtaa tcatatattt
    53041 gcattttgtt cctccttatt gaagagatca atcaaaacct ttatttaacg atcctttttc
    53101 tacagaaaac aagtgtaaca cttttcttga attttgtatg cgaagatgct taaaacaggg
    53161 atatatcagc tttttcctta tttacgtttt cggatcatat ctccaggttt caccggctgt
    53221 gcgactggca tagttaaaat catcattgga tttggtgctc ggtcaatgga ttcgccttct
    53281 tcattatgca taacttcaac ggtttgactg aaatgactga atcctggacc ataaaattcg
    53341 atttcatctc ctacagaaaa caagtttctc tgacgtatcg tagcaatctg tgttgcctca
    53401 tcataagata atacttcacc gacaaattta tatactggga ttttacgacg ttcaccgaat
    53461 aattgttcgt tttcagttgg tgtattgtag taaaaacctg tagctaattc tcgttgtgct
    53521 actttccata actcgtcgat ccattcttgc ttgcagacat agttttcagg atcttccata
    53581 taactgtcta cagccgcttt atagacattt gacaccgtag atacataatg gatcgatttc
    53641 attcttcctt cgatcttgaa gctgtctacg ccgttttcaa tcaattctgg aatatgttcg
    53701 atcattgaca tatccactgc actcatcgag aattcttctt ccacttcgcc tgtatcagtt
    53761 aaactgtttc gttcttgacc aaaaggcata tcgaacaatc catacttcca gcgacaagat
    53821 tgagaacatc cgccacggtt tgcatcccgc atcgacatat ggttggacaa tgtgcatcga
    53881 ccagaataag agatacacat ggcaccatgg ataaatgctt cgatttcggt atccgtattt
    53941 ttacgaatct ctgccacttc ctccattgaa acttcacgag ctaaaacgac acgttccaac
    54001 ccttcttctt tccagaattc caatgtctca aaattagttg ctgaagcttg agtggataaa
    54061 tggatcggca gacctggggc ttctgtcgca caaatttcga tcaaagctgg atcagaaaca
    54121 atcactgcag aaataccgac atcacgcaaa ctgcggaaaa attcccctgc tccatcttca
    54181 tttccttcat gggtgaccat attagcagca acgtatacct tcgcatcatg ttcttttgca
    54241 aaagcaactc cttcagccat ttcttcataa gtaaaattac ctgcacggct tcttaaacca
    54301 tatgcattcc cgccaatata tactgcatct gctccataat ggatcgcggt ttttaacttt
    54361 tccagtgttc ctgctggcgc taggatttct ggtcgtttca attttctttt tactgtcatt
    54421 tctttcatca tactccttat ttgatagcag aaggatcaat ataaaagaat cctgtatcta
    54481 attcacggtt ttcaggatgc aatttactga tttcgctagt cattttttcc gctttttctt
    54541 gatcccagct accttctaaa atttgttttt ttgcttcggc gaatagtcga gtgatgttta
    54601 cgaatttttc gcctggagta aataatccgt ccaatttcca tgtacagtaa tgatgctgat
    54661 aaagttcatt caattcattc gagagattca gatcattgct ggcaaaaata tgtgtgccat
    54721 gactatcttc ataaatagaa taatgtgtct cttctttttt aggttccgag ataaaaagac
    54781 ctctttcacg atctttttgt tcgtcttgtt tcgtatagtt atagtaattc tgtagcagtg
    54841 gacgtttgga ttgatggatg catgtagcac catacacaag ggtttctaca ggaatatcga
    54901 gtttttcttc catcgccttc atctcttcaa aaggaacttc acgagcaagt actgctccaa
    54961 ctgcgccttt tttcgcccag aaattgattt gacgtgcgct cgttactaat gtttcagcat
    55021 cataaatata cggtatacgc aattcaggat tttttttcat cgtataaata atacctgtat
    55081 caccaactgt gatcacatct acgtttattt cttttaaaaa agccaaatat tcaggtacat
    55141 ttttcatttt ttcaggatga atgatcccat ttacagcaat attcgctttt ttaccatact
    55201 tgtgtgctaa ttctaccaat tgtcgctgtt cttctcgtgt aaatgaagca ggcagacgca
    55261 atccaaattg ctcttcaccg aaatatagtg tatctgcacc tgcagcaagc aactgttctg
    55321 cttgttcaat agtttctact gtggttatga gttcgatcat aattttctcc tcctacaact
    55381 tcataatagt agcatagctc taaaaacttt ccaatacttc ttctatttaa agtcggattt
    55441 ttgaaaatta tttcacaaaa aatcaaaata aagttcgata tattctgtcc aaatataaaa
    55501 agagattgtg acaaaaatct tgtcacaacc tcttaatcaa gtcttactat tataaaaatt
    55561 cagctacaca ggccaagtaa ctatagggaa cctactgttt cctttttagg tccgcgaaca
    55621 ttcaatgtga tcttaccttt tgaagcacct actgttacgt ggtcacctaa acgaatttct
    55681 ccgccaagca aagcctcgct caatcgatct tcaatttctt tttgaagtgc gcgacggatt
    55741 ggacgtgcac catattcagg atcaaatcca gctttcccga tcacatcgat tgcagatggt
    55801 gtgattttca cttgaatatc ttgttctttc aatcgtttga taatcgcttt gctcatgatt
    55861 tggacgattg tatggatttc atctttactc aatgaatgga agacgacagt ctcatcgatt
    55921 cgattcaaga attcaggtcg gaaagctttc tttaactctt ctaagatacg tttttgcatg
    55981 gctttgtgat ctttagtaac atcttggaca ttgaatccga catttttttc ttctcgaatt
    56041 tgtgtcgctc cgatatttga agtcataatc atgattgtat ttctaaagtc cacttttcta
    56101 cctttagaat ctgttaaatg accatcatcc aatacttgca gaagtaaatt gaaaacgtct
    56161 ggatgtgctt tctccacttc atctaagaga atcactgaat atggtttttg acgaattttt
    56221 tctgtcaact gtccaccttc atcataccct acgtatcctg gaggagaccc gattaatcgg
    56281 cttgtactgt atttttccat aaattctgac atatcaacac ggatcagggc atcttcactt
    56341 ccaaacatga cttctgaaag tgctttggcc aattctgttt ttccgacacc agttggtcca
    56401 aggaacatga atgaaccaat tggacgatca ggatctttca atccgcttcg tgcacggcgg
    56461 atcgcacgtg aaactgcttt gacagcctca tcttgaccaa cgacacgttc atgcagaagt
    56521 ccttccagtt ctaacaagcg ttcgctttct tttttctcca actgctgtag agggacacca
    56581 gtccactccg atacaactgt agcaacatct tcttctgtta cacgatcaga ataaccttgc
    56641 tcctgttttg cttcaattgc agaaactttt tgcagctttt tacgtagtgc tttttcttgt
    56701 ctgcgtaatt gagcagcatt ttcaaagtct tgtttttgga tcgctgcttc cttttcttgt
    56761 actagttcat cgatttctag tttgatcaca gttgattttg ttaagtgatc ggtttgatcc
    56821 aaacggactt tcgctgctga ttcatcgatc aaatcaattg ctttatcggg tagttgacga
    56881 gaagtgatat aacgaacaga aagattgact gctgctcgta cagcttcatc tgtgatctcc
    56941 actccatggt gctcttcata tcttgtacgt aatccttgaa gaatcacttc tgcttcttca
    57001 ggagttggct catctacttg aatgcgagca aaacgtcgct ctaatgcaga atctttttcg
    57061 atatattttt gatattcatc tagggtcgtt gctccgatcg tttgtaattc tcctcgagct
    57121 aacgccggtt tcaagatatt cgaagcatca attgctcctt ctgctccacc tgcaccaatt
    57181 aaggtatgca attcatcaat gaataagatt acttgaccat cattatagat ttcgtcgatg
    57241 acctttttca ttcgatcttc aaattcaccg cgatatttcg taccagcaac caaagatccc
    57301 atatcaagca tcatcaggcg cttttcttgc atgtcttctg gcacttcacc taaaatgatt
    57361 ttttgagcta acccttcagc aatggctgtt ttgcctacac caggttcacc caccagtaca
    57421 gggttattct ttgtccgtcg gctaagaatc tggataagcc gtttcacttc tctcgaacga
    57481 ccaacaactg ggtccagctt gttttctttt gctaatttcg tcaaatcacg tgctaatgaa
    57541 tctagcgtag gtgttccttg cggtgtttgc cgtttatctt gtacatttac atttctacga
    57601 cgattcattc cttttccagc agaatcacca gctagcccca ttttttgttt cagaacttga
    57661 cgggcttttg aaaggctgat acctaagttg atcatgattc gagtagccat gatactttca
    57721 tcttttaata agctcatcaa aatatgttct gttccaactt tttgagaacc agttttcttc
    57781 acttcgctgc tagctaaagc aaaaacttgt ttcattcttg gtgaatatgg aagaaagact
    57841 cctttagggt aagaacggat accaccataa ccaatcagat gttcaatttc ttcataaatt
    57901 tccgtttcat tcaaatccat ttcacgtaat acttttccag caattccatt ttgctcgacc
    57961 actaaggcta gtaaaacatg ttctgaacta actgattgat gtttcaaccg ttttgcttct
    58021 tcttgtgcaa tttctaatac tgcttgggct ctttcagtaa aaagttcttc catctaatct
    58081 cacttcccat cttcataact taaacgttcc agaaatgctc ggagaatccg agcacgtgta
    58141 tgatcttcat attcattgaa attcaatgtg ttttttgcaa ttgcactcaa catcaagttt
    58201 ccttcttttt ttgtaattat ttggtcttca taaagttttt gaataatagc aaaagcattt
    58261 ttctcactga ttgtatcatc aaataactga tttatctgct caagtaattg ttttttatct
    58321 gaaatcctta cttttgcaat tcgtatataa ccaccaccac cacgtttgct ttctactaga
    58381 taaccacgtt ggatggtaaa acgggtatta atcacatagt tgatttgtga aggaacacag
    58441 ttaaagaggt ctgccatttc aatccttcga atctcgatca tttcactatt ttccagaatt
    58501 ttctttatat atgattcaat taaatccgag gtattctgat gtgccatctt attcattccc
    58561 tttgactaat attgacctta attataacga atttgataat agaaagaaag aagaacgctt
    58621 tttgttaaat aaatccttta gaatcaacaa aaaaaaatac ggaatatact attccgtatc
    58681 gacgcgccca agaggagtcg aacccctaac cttttgatcc gtagtcaaac actctatcca
    58741 gttgagctat gggcgcatat tcaatttaaa aaaattataa atcatttgaa aacaaaaagc
    58801 aagataaaaa aaatcgggaa gacaggattc gaacctgcga ccccttggtc ccaaaccaag
    58861 tgctctacca agctgagcta cttcccgttt aaaaaataaa aaagac
//
LOCUS       DAFKHN010000007        55340 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFKHN010000007 DAFKHN010000000
VERSION     DAFKHN010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.007"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..597)
                     /locus_tag="LY912_000433"
     CDS             complement(<1..597)
                     /locus_tag="LY912_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6954154.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
     gene            790..1821
                     /gene="queA"
                     /locus_tag="LY912_000434"
     CDS             790..1821
                     /gene="queA"
                     /locus_tag="LY912_000434"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBM6954155.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            2440..5079
                     /locus_tag="LY912_000435"
     CDS             2440..5079
                     /locus_tag="LY912_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBM6954156.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(5247..5945)
                     /locus_tag="LY912_000436"
     CDS             complement(5247..5945)
                     /locus_tag="LY912_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBM6954157.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            6162..7307
                     /gene="tgt"
                     /locus_tag="LY912_000437"
     CDS             6162..7307
                     /gene="tgt"
                     /locus_tag="LY912_000437"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBM6954158.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            7404..7784
                     /gene="yajC"
                     /locus_tag="LY912_000438"
     CDS             7404..7784
                     /gene="yajC"
                     /locus_tag="LY912_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBM6954159.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            8089..10686
                     /gene="adhE"
                     /locus_tag="LY912_000439"
                     /gene_synonym="adhC"
     CDS             8089..10686
                     /gene="adhE"
                     /locus_tag="LY912_000439"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBM6954160.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            10915..12021
                     /locus_tag="LY912_000440"
     CDS             10915..12021
                     /locus_tag="LY912_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBM6954161.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            12038..13066
                     /locus_tag="LY912_000441"
     CDS             12038..13066
                     /locus_tag="LY912_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBM6954162.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            13072..13551
                     /locus_tag="LY912_000442"
     CDS             13072..13551
                     /locus_tag="LY912_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBM6954163.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            13567..14862
                     /locus_tag="LY912_000443"
     CDS             13567..14862
                     /locus_tag="LY912_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBM6954164.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            14873..15697
                     /locus_tag="LY912_000444"
     CDS             14873..15697
                     /locus_tag="LY912_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBM6954165.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            15862..16761
                     /locus_tag="LY912_000445"
     CDS             15862..16761
                     /locus_tag="LY912_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6954166.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(16887..17756)
                     /locus_tag="LY912_000446"
     CDS             complement(16887..17756)
                     /locus_tag="LY912_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBM6954167.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            17909..19369
                     /gene="rhaB"
                     /locus_tag="LY912_000447"
     CDS             17909..19369
                     /gene="rhaB"
                     /locus_tag="LY912_000447"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBM6954168.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            19366..20622
                     /gene="rhaA"
                     /locus_tag="LY912_000448"
     CDS             19366..20622
                     /gene="rhaA"
                     /locus_tag="LY912_000448"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBM6954169.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            20636..21481
                     /gene="rhaD"
                     /locus_tag="LY912_000449"
     CDS             20636..21481
                     /gene="rhaD"
                     /locus_tag="LY912_000449"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBM6954170.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            21483..21794
                     /gene="rhaM"
                     /locus_tag="LY912_000450"
     CDS             21483..21794
                     /gene="rhaM"
                     /locus_tag="LY912_000450"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBM6954171.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            21876..23027
                     /gene="fucO"
                     /locus_tag="LY912_000451"
     CDS             21876..23027
                     /gene="fucO"
                     /locus_tag="LY912_000451"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBM6954172.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            23154..23912
                     /locus_tag="LY912_000452"
     CDS             23154..23912
                     /locus_tag="LY912_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBM6954173.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            24012..24656
                     /locus_tag="LY912_000453"
     CDS             24012..24656
                     /locus_tag="LY912_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBM6954174.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            24663..25670
                     /locus_tag="LY912_000454"
     CDS             24663..25670
                     /locus_tag="LY912_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBM6954175.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            25686..26528
                     /gene="kduI"
                     /locus_tag="LY912_000455"
     CDS             25686..26528
                     /gene="kduI"
                     /locus_tag="LY912_000455"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBM6954176.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            26548..27351
                     /locus_tag="LY912_000456"
     CDS             26548..27351
                     /locus_tag="LY912_000456"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBM6954177.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(27600..28664)
                     /locus_tag="LY912_000457"
     CDS             complement(27600..28664)
                     /locus_tag="LY912_000457"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBM6954178.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(28661..29746)
                     /locus_tag="LY912_000458"
     CDS             complement(28661..29746)
                     /locus_tag="LY912_000458"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBM6954179.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(29759..30736)
                     /gene="mvaD"
                     /locus_tag="LY912_000459"
     CDS             complement(29759..30736)
                     /gene="mvaD"
                     /locus_tag="LY912_000459"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBM6954180.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(30729..31673)
                     /gene="mvk"
                     /locus_tag="LY912_000460"
     CDS             complement(30729..31673)
                     /gene="mvk"
                     /locus_tag="LY912_000460"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBM6954181.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            31989..32648
                     /locus_tag="LY912_000461"
     CDS             31989..32648
                     /locus_tag="LY912_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBM6954182.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            32733..33638
                     /locus_tag="LY912_000462"
     CDS             32733..33638
                     /locus_tag="LY912_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBM6954183.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(33640..34272)
                     /locus_tag="LY912_000463"
     CDS             complement(33640..34272)
                     /locus_tag="LY912_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBM6954184.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    34423..34548
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            34592..35116
                     /gene="infC"
                     /locus_tag="LY912_000464"
     CDS             34592..35116
                     /gene="infC"
                     /locus_tag="LY912_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBM6954185.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            35188..35388
                     /gene="rpmI"
                     /locus_tag="LY912_000465"
     CDS             35188..35388
                     /gene="rpmI"
                     /locus_tag="LY912_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBM6954186.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            35441..35800
                     /gene="rplT"
                     /locus_tag="LY912_000466"
     CDS             35441..35800
                     /gene="rplT"
                     /locus_tag="LY912_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBM6954187.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            36052..37389
                     /locus_tag="LY912_000467"
     CDS             36052..37389
                     /locus_tag="LY912_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBM6954188.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            37437..39566
                     /locus_tag="LY912_000468"
     CDS             37437..39566
                     /locus_tag="LY912_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBM6954189.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            39541..40230
                     /locus_tag="LY912_000469"
     CDS             39541..40230
                     /locus_tag="LY912_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954190.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(40638..41324)
                     /locus_tag="LY912_000470"
     CDS             complement(40638..41324)
                     /locus_tag="LY912_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6954191.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QVKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(41460..41654)
                     /locus_tag="LY912_000471"
     CDS             complement(41460..41654)
                     /locus_tag="LY912_000471"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954192.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(41704..42144)
                     /locus_tag="LY912_000472"
     CDS             complement(41704..42144)
                     /locus_tag="LY912_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBM6954193.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(42148..42993)
                     /locus_tag="LY912_000473"
     CDS             complement(42148..42993)
                     /locus_tag="LY912_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBM6954194.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            43142..44560
                     /gene="pepV"
                     /locus_tag="LY912_000474"
     CDS             43142..44560
                     /gene="pepV"
                     /locus_tag="LY912_000474"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBM6954195.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(44617..45564)
                     /locus_tag="LY912_000475"
     CDS             complement(44617..45564)
                     /locus_tag="LY912_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBM6954196.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(45787..46137)
                     /locus_tag="LY912_000476"
     CDS             complement(45787..46137)
                     /locus_tag="LY912_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBM6954197.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            46337..47416
                     /gene="pepA"
                     /locus_tag="LY912_000477"
     CDS             46337..47416
                     /gene="pepA"
                     /locus_tag="LY912_000477"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBM6954198.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            47560..47880
                     /locus_tag="LY912_000478"
     CDS             47560..47880
                     /locus_tag="LY912_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBM6954199.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            47902..48366
                     /locus_tag="LY912_000479"
     CDS             47902..48366
                     /locus_tag="LY912_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBM6954200.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            48571..49176
                     /locus_tag="LY912_000480"
     CDS             48571..49176
                     /locus_tag="LY912_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBM6954201.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(49215..50504)
                     /locus_tag="LY912_000481"
     CDS             complement(49215..50504)
                     /locus_tag="LY912_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBM6954202.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            50932..51411
                     /gene="rlmH"
                     /locus_tag="LY912_000482"
     CDS             50932..51411
                     /gene="rlmH"
                     /locus_tag="LY912_000482"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBM6954203.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            51764..52078
                     /locus_tag="LY912_000483"
     CDS             51764..52078
                     /locus_tag="LY912_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBM6954204.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            52094..52480
                     /locus_tag="LY912_000484"
     CDS             52094..52480
                     /locus_tag="LY912_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBM6954205.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            52509..53894
                     /locus_tag="LY912_000485"
     CDS             52509..53894
                     /locus_tag="LY912_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBM6954206.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            53897..54050
                     /locus_tag="LY912_000486"
                     /pseudo
     CDS             53897..54050
                     /locus_tag="LY912_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            54073..55278
                     /locus_tag="LY912_000487"
     CDS             54073..55278
                     /locus_tag="LY912_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBM6954207.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
BASE COUNT        17556 a        10114 c        11872 g        15798 t
ORIGIN      
        1 cgcttcatcc atgtcatggg ttacaaatac gatcgttttt cccaaacgct cttgtaaatc
       61 tttgacaagg tcttgcaagg aatcacgagt gattggatca agcgcaccga atggctcgtc
      121 catcaagatg atatcttgat tcgctgcaag ggcacgaacg actccaatac gctgctgctg
      181 accaccagat aattcatgtg ggtagcgatc taacatctca cggggcaatt ccacaagatc
      241 aatcattttt tcagctgttt tattccgttc ttcttgactg actttcaaca atttttggac
      301 aagagtgata ttttcacgga tcgtcatgtg aggcatcaat ccaatacttt ggataacata
      361 gccgatctga cgtcgcaatt ccactggatc aatttcttgg atggattttc catcaatcaa
      421 aattttccct tgtgttggat cagtcattcg gttgatcatc cgcatcgtcg tcgtttttcc
      481 gcttccgctc gtaccgataa aacaaatgaa ctcacccttt tcaaatgaaa gattgacgtc
      541 ctctacagcg acttttccac ctttataaat ttttgacaca ttttgaaatt caatcatggt
      601 gccacctctt tttctatttt caatgaagaa ctatctatta ctagtatgcc taaaacaatg
      661 aaaaaataca aatagggtag tttttttatt taggaaaaca aaaaatagaa gtgaaaaagt
      721 gctgattttg ccaacagaac gaaaaacatg atagaatgat gaagcacatg atagaaagtg
      781 agtgacgata tgttaacaac agaagatttt gattttgact tgccggaaga attaatcgca
      841 caaacaccat taaaagaccg cgatcattct cgtttacttg ttttggatcg gaaaactgga
      901 gagatggaag ataaacattt ccatgaaatc attgaagagt tacagcctgg tgatgcgcta
      961 gttatgaata atacacgagt tctgcctgct cgtttatatg gagaaaaacc agatactggt
     1021 gcgcatttag aagtccttct tctaacgaat acacaaggag atacgtggga gacattgatc
     1081 aaacctgcga aacgtgccaa agttgggaca agaatctctt ttggtgatgg cagattgcaa
     1141 gcagtagtga aagaagaatt ggaacacggc ggacggatca ttgactttga gtatgaagga
     1201 atttttctag agattcttga atcattggga gaaatgccat tgcctccata tatcaaagaa
     1261 cgtctggaag acccagatcg ctatcaaact gtctatgcga aagaaaatgg ttctgctgca
     1321 gcgccaacag ctggattgca ttttacgaaa gaattacttg atgagatcga agcaaagggt
     1381 gttgaattag tctatctgac actacatgta gggttaggta cattccgacc tgtcagcgta
     1441 gataaaattg aagaacacca tatgcatagt gaattctacc gtttgacgga agaagcggct
     1501 gagcgattga accaagtacg taaaaatggc gggaaaatcg tggctgtcgg aacaacttca
     1561 attcgaacat tagaaacgat tggaacgaaa tttaatggag aaatcaaagc agacagcgga
     1621 tggactgata ttttcattac gcctggctat gaattcaaag tggtagaagc tttctcaact
     1681 aatttccatt tgccaaaatc gactttagtc atgttagtta gtgcctttgc aggaagagaa
     1741 ttgactttat ctgcttacca gcatgcgatt gaagagcgct atcgtttctt tagttttgga
     1801 gatgcgatgt tcgtgaaata aggttatgaa aagccgctag ttttgaataa caaaaaagct
     1861 ttacaaagat tttatgacaa agaaaaagcc gagctctcga taagctcggc tttcttgtac
     1921 ctcggaagga ttcaaataaa cagaaatgat tgtaactttc catcatacat gcaaagcacg
     1981 gtgttgaatt tcttcatgtt aaacaaaaat tttgttttcg ttacatcttc aacatttgaa
     2041 acatctcttg ttcctattca attttcagac gtttacgtta ttcaattgtt acgtatcgca
     2101 ttacttcttg tttcggatac ttcgtgatcc aaacatccat acgcattcac tatttatagg
     2161 tttgtactct acacgcatgt ctgggtgaaa cctgtacttc taacaacttt gtttgcttac
     2221 actgttctat cgagaaattc ttctgtctat ttgatggtat cctccttcct tacatctata
     2281 taatagcatc ctttggtagc gtttgcaaat ataagcactt taaattttac gctttcttaa
     2341 caaataatcg ataagccctt tatttgaagt aaataaaaaa aggatgttat agtaaaataa
     2401 gtaccttttt ttgtacgaag attttaaagg aggaatagga tggaagaata caagcagaca
     2461 atagaagaag taaagaaggt aacagaagca gatccagata ctgggttgtc ttcacaagaa
     2521 gtggatgaac ggcgaaaaaa gcagggattg aataaattcg atgaggcgcc gaaagaatcg
     2581 atgatcaaaa aattctttcg aagcttgtcc gattttacaa cgatcatcct tcttgtagca
     2641 gcggtgattt ccttttatac cgcatttgct acagaacatg gggatttatt tgaaggactg
     2701 ctgatcatcg ctatcgttgt gatcaactcg gtattggcga ttgtccaaga aggaaacgca
     2761 gaaaaagcac tggaatcctt gcaagatatg aataaacaaa cggcaactgt catacgagac
     2821 ggcaaagtga ccactgttga gtcagagcaa ctggtagtgg gtgatattct tgttttagag
     2881 tccggtgatg ctatttctgc cgatgcccgt ttgatcgaag catcacaatt acgtgtagaa
     2941 gaatcggcgt tgactggaga aagtgaagca gttgaaaaag atgcagcatt tattgctgaa
     3001 gaagatgagt cattaggtga ccaacttaat atggtattta aaggatgtac ggttgctgca
     3061 ggtcgtggga aagcgatcgt cactgccatt ggcatggcta cagaaatggg taagatcgcg
     3121 gatcttttga acgaaaatac tatgcaaaaa acacctttac aggtccgatt gaatcagcta
     3181 ggcaaacgaa tcagtatgat cgctttagcg gctgcggctt tagtatttgt gattggtgaa
     3241 ctgcaaggag aaccactcct tgagatgttc atgacttcga tttccttggc tgttgcagct
     3301 gtaccggaaa ccttgactgt tattgttacg ttgacacttg catacggtgt gcagaagatg
     3361 gcgaggaaac atgcgatcat ccgacagttg ccagcagttg aaacgctagg aaccgctaat
     3421 gttatctgct cagacaaaac aggaacgctg acacaaaatg aaatgcgcgt ccgccgggta
     3481 tggagcaaag aagatgaagt aacgaatatc gaagattcaa tgacgaacag cgcgatggaa
     3541 atattgaaaa tggctgcact atgtacagat gtgacggtcg agcaagaaga tgacgacctt
     3601 gttatcaaag gtaatccaac agaagtagcc atcgtaaggg ctgttgaaga gaattatcat
     3661 acaaaggcag aattagaaga aaaatatcca cgagtaaacg agcttccttt tgattctgaa
     3721 cgaaaaatga tgacaacagt tcaccaaatg ggcgaaaaat acatctcaat caccaaagga
     3781 gcattcgatg ttcttgctcc gcgctttagt tcaggcgatg tagaacaagc ggcgatcgtt
     3841 aatgatcgct ttggtaaacg ggcactgaga gtgattgctg ttggttatgc tacttatgac
     3901 gaagaaccgc aagatatttc ttctgaagca ctggaaaaag acttacgttt gattggtctg
     3961 atcggaatga tcgatccacc acgtccagaa agtaaaggag caatcaagcg agcgaaaaag
     4021 gctggcatca aaacagtcat gatcactgga gatcatgtgg tgactgccag tgccatagcg
     4081 aaagaattag gtatcttgaa tgatccgtca gaagcacttt caggatcaga actgcatcaa
     4141 ttatcagacg aagaattaga tgcgcgtgtc aaagctctct ctgtctatgc tcgggtaacg
     4201 ccagaagaca agatccggat cgtcaaatct tggcaacgta cgggtgcagt cgtagcgatg
     4261 actggggatg gtgtgaatga tgcaccagcg ttgaaagcaa gtaacgttgg gtgtgccatg
     4321 gggatcacag gaacagatgt ggcgcaaagt gccgcagata tgattttgac ggatgacaac
     4381 tttgcgacga tcgtagacgc tgtcagtcaa ggacgttcgg tttatcagaa tattcgtaaa
     4441 gctatcaact ttttgctaag ctgtaatatt tcggagatct ttattgtttt gattgcgatg
     4501 ctgttaggat ggggagcacc atttacagct gtgcaactac tgtttgtcaa tgtagttgct
     4561 gatggacttc caggatttgc tttaggaaga gagccagcgg aacacggcat catggatcag
     4621 ccacccattc cgaaaaatga agggatcttt gctcgaggtt tattgcaaaa aattgccata
     4681 aatgcagggg tcttcaccat cgtaaccttg tttggttatt atttaggtag ttatgtcgat
     4741 actatcagcc catgggtaga cgcaagtcag catgtcggtc aaactgttgc attcttgatc
     4801 ttagcttatt catcgattct gcatgtgttc aatgtacgca gcagccaatc gatcttcaaa
     4861 gtcaatttag cgaccaataa agctttggta gaaatggcgt tactggcatt agctattaca
     4921 acggctgttg ctttgctgcc atttacgcaa gaactattcg gcctagtaca catcagtttg
     4981 aatcactggt tcttggtagg gattttatct atcgtaccaa tcgcggtgaa tgaactgatc
     5041 aagttccatc gattaccgga agcagaagaa gaggaatgat taactgtttc taagttgatt
     5101 ttctttttac tggaactata caaaaaggag gtgtgacatg aatgttgtca cacctccttt
     5161 ttgctaatgg gctgaatgtt tcttttactg cctctcgata aacggtgttc tcctgccacc
     5221 ccctcggtca caagtcacac tctcttttaa atatcttttg gcaattgttc ataaaatgct
     5281 gcttttgttg cagaaatgta tgggctgagc catagataac caataccagc agttgctaat
     5341 gctaagatat gccagccgat aaatgaaaga tctaaccaga aaagttgtcc tttataacca
     5401 tccatcaatt ttcgacttgc agtgatcgta tccagtactt taggtgtttg tcctgtttct
     5461 tggacgatat cgtagtaaat aaaatagctt tgagaataag aatagctttt aatgattcca
     5521 ggaataacta atagcaaacc ccataatgtt gtaaagatcg agatcagcac agctaagctg
     5581 atcactccgc cgataaacaa acctttgaat ccacgaaatg catctttgaa tggttcgatc
     5641 tgatcttttt gtccacgtaa aatatcaaga taagtccaag aaataccgct catgaacaaa
     5701 gcgctaatga tgctggaaat aattccgcca ccgcctcctg aactaccgcc tcctgaagtt
     5761 gtcgcttctg agacgctcgc tgatccatca tatatggtgg tggcaaacaa gataatagga
     5821 atcataataa gaagaatagt agcaatacca atcaatgtag ggattagatt tagtaaaaca
     5881 gcttgtcccc aacgtccttt tagactctct tttgcttggc gttttaattc tgcagaagat
     5941 tgcatgattt ttccctcctt ttctttaata acaccaatat accatgtatc aaaaaatatt
     6001 tctgtcataa tgtttttctt ttttttgtta ttcataaaaa aaggataaaa aaagaatatt
     6061 aaataaagta gaaggaagcc gagggaactt gcaaaaagca cttgaaacga ttatgatggt
     6121 gggagttgtc aagatatttt atatagaaag tagggaaatg aatgacgcaa cctgccattc
     6181 gctatcgttt aatcaagaaa gaaaaacata ctggcgcgcg tttaggggaa ttgatcacgc
     6241 cacacggaac tttccccaca ccaatgttca tgccagtagg aacattagct acagtaaaaa
     6301 caatgtcccc agaagagttg aaagaaatgg gtgctggcgt tattttaagt aatacatatc
     6361 atttatggct acgccctggt gaagacttag tagaagaagc tggcggactg cataaattta
     6421 tgaactggga tcaaccgatt ttaacagatt caggcggctt tcaagttttt tcattaagtg
     6481 atatgcggaa tatcgaagaa gaaggcgtgc atttcaaaaa tcacttgaac ggttcgcgta
     6541 tgtttttatc accagaaaaa gcaatcaaca tccaaaataa attgggctct gatatcatga
     6601 tgagttttga cgaatgtcca ccattcgatg aaagttacga ctacgtgaaa aaatcagtag
     6661 aacgtacgtc tcgatgggca gaacgaggat tgaaagctca tgctaatcca gaccgtcaag
     6721 gattatttgg aatcatccaa ggagcagggt ttgaagatct tcgtcgtcaa agcgcgaaag
     6781 atctagtcgg gatggatttc cctggttact caatcggcgg gttatctgtc ggggaaccta
     6841 aatcagaaat gaatcgtgta ttagaattca ctacaccgtt gatccccgaa aacaaaccac
     6901 gttacttgat gggtgtcggt gctgctgatt cgttgatcga tggtgttatc cgtggagtag
     6961 acatgtttga ctgtgtcttg cctactcgaa tcgctcgaaa tggcacatgt atgacttctc
     7021 aaggccgtct agtagtgaaa aatgcgaaat atgcccatga tttccgtcca attgatgaga
     7081 aatgtgattg ttatacatgt aaaaactata cacgtgccta tatccgccat ttgatcaaat
     7141 gtgatgaaac atttgggatt cgtttgactt cttaccacaa tttatacttc ttgttgaatc
     7201 taatgaaaca agtacgtcaa gcaatcatgg atgataattt gcttgaattt agagaagcct
     7261 tttttgaaga atacgggttc aataaagaaa acgcaaaaag cttctaaagg aaaatctttt
     7321 aaaaattaag taaaaaacta gtgttatcag catttttctg ctaaagtgtt ttttgtagat
     7381 acagaattag tgaggtgaaa aaaatgggaa cattaccaat gcttgtgatg tttatcgcgc
     7441 tattagcaat gtggtttttt atgtcacgtt cgcaaaagaa acaacagcaa gaacgtcaaa
     7501 acttgttaga tagcatgaaa ccaggtgatt cagtcgtaac gatcggcgga ttacatggag
     7561 ttgtttcaga aatcgacaat gacaaacgga cagttgtttt agactgcgaa gggatcttcc
     7621 ttgagtacga tcgtgcagca atcaaaacgg tcaaaccagg gactgtcgta acaaatgatg
     7681 caacgactac tgttgaaaca acagaagaac cagctgagac agttgaagta aaaactgaaa
     7741 caacagaaac gctggaagag acagaagaga aggaagaaaa ataagtatca aagcttattt
     7801 aaagacgagg tagggcagaa agatgtccta cctcattttt tattcaaaaa agaaagagat
     7861 aagagcatgg gatatattgc tcaatattga ataatcgggt gtgtcatata aataataata
     7921 aataacttta tatatttttc tatacaaaca cctgtaaata aagcaatttt atatttaaaa
     7981 ataactgtga aaaaaatcac aaaaaagtgt ttacatagaa aaataaatat tgtatgatat
     8041 acatgtgaat tatttaacaa ataaccatga cccattagga ggataatgat ggctaaagta
     8101 atagaaaaag aaaaaacgaa gacaattgac gtacaagcaa tgattgatga tttggcagaa
     8161 aaagcaaatg cagcattgaa agaaatggaa agctttgatc aagaaaaagt agaccatatc
     8221 gtgcatgaaa tggcaatggc agctttggat caacatatgc cattagcgaa gatggctgta
     8281 gaggaaacag gccgcggtgt ttacgaagat aaagcaatca aaaatatgta tgcgtccgaa
     8341 tatatttggc ataatatcaa acatgataaa acagttggtg tgatcaatga agatgtccaa
     8401 aaagggttga ttgaaattgc tgaaccagtc ggtgtggttt gcggagtaac tccaacaacg
     8461 aatccgactt ccacaacgat tttcaaatca atgatcgcgt tgaaaacaag aaatccaatc
     8521 gtttttgctt tccatccaag tgcccaaaaa tcttctgcag aagcagcacg agtggtacgt
     8581 gatgctgcta tcgctgccgg agctcctgaa aattgtatcc aatggatcga acatccttcg
     8641 atcgaagcga cttctatgct aatgaaccat ccaggtatcg cgatcgtctt agcgacaggt
     8701 ggagctggaa tggtcaagtc tgcttactct acaggaaaac cagctttagg tgtaggtcca
     8761 ggtaacgtac cagcttatat tgaaaaaaca gcaaaaatta aacgtgcagt gaacgatttg
     8821 atcgtttcga aaacatttga taatggaatg atttgtgctt ctgaacaagc tgtgatcgtg
     8881 gataaagaaa tctatgcagc agtaaaagca gaattccaag cacaccaagt ttatatcgta
     8941 aaaccagatg aattgcaaaa attagaagat gcagtgatga acgaaggaaa atatgcggtc
     9001 aatccatcaa tcgttggaca ttctgcgatg gaaatcgcaa aattggcagg aatcagtgta
     9061 ccaaaaggaa cgaaaatgct gattgctgaa ttggaaggcg taggcccaga ttatccgcta
     9121 tcaagagaaa aactttctcc agttcttgcc atgatcaaag ctaacaacac ggaccatgcg
     9181 tttgatttgt gtgaaggtat gttgaatctt ggaggattag gacatacagc agttatccat
     9241 tcagaaaacg aagagttgca tgtcaaattc ggtcttcgaa tgaaagcttg tcgtatttta
     9301 gtgaatacac catctgcaga aggcggcatc ggtgatatct ataacgaaat gattccgtca
     9361 ttgactttgg gatgcggttc ttatggtaag aactctgttt ctcgtaacgt ctctgctgta
     9421 aacttaatca atgtcaaaac tgtagcgaaa cggagaaata acatgcaatg gttcaaatta
     9481 ccgccaaaaa tcttctttga aaagaactct ctattgtact tagagaaaat ggaaaacgtt
     9541 gaacgtgtca tgatcgtttg tgaccctggt atggtccaat tcggttactg cgatacagtt
     9601 cgtgaagtat tggcacgacg taaaaatgat gtgaagatcg aagtcttctc agatgttgaa
     9661 ccgaacccat cgacaaatac cgtatacgca ggaacgaaac tgatggcaga cttcaagcca
     9721 gatacagtaa tcgctcttgg aggcggttct gcaatggacg cagctaaggg aatgtggatg
     9781 ttctatgaac acccagacac atctttcttt ggtgcaaaac aaaaattctt ggatatccgt
     9841 aaacggacat ataagatcga caaaccagaa aaaacacaat tcgtatgtat cccgacaaca
     9901 tcagggactg gttctgaagt aacgccattt gcggtcatca ctgacagtga aacacatgtg
     9961 aaatatccgt tagcagatta tgcattgacg ccagatgtcg caatcgtcga tcctcaattc
    10021 gtcatgtcag ttccagcatc tgtcacagca gataccggga tggatgtgtt aacacatgca
    10081 atcgaatcct atgtttcagt catggcttca gattatacac gtggattgag cctacaagca
    10141 atcaagttag tctttgacta tttagaaaaa tcagtaaaaa cacctgatat ggaatcacgt
    10201 gaaaaaatgc acaacgcttc tacaatggct ggtatggcgt ttgctaacgc attcctaggt
    10261 atttgtcact cagtcgcaca taaaatcggc ggggaatacg ggatccctca tggacggaca
    10321 aatgcgattc ttttaccgca tattatccgc tataatgcaa aagatccaca aaaacatgcg
    10381 atgttcccta aatatgacta tttccgtgca gatacagatt acgcagatat cgcaaaattc
    10441 ttaggtctga aaggcgaaac aacagaggaa ttagtcgaag ctttagcaac ggctgtttat
    10501 gaattaggaa aatctgtcgg catcaacatg agtctaaaag ctcaaggagt cacacaagaa
    10561 acactagata caaccgtaga ccgtatggct gaattagctt acgaagacca atgtacgaca
    10621 gctaatccga aagaaccatt gatctctgaa ttgaaacaga tcatcattga tgcttacaac
    10681 ggataagcaa aagaaagcgt agaaaaaaga taagaaaata gatgaaaaag aacttggaaa
    10741 acgttgtttc tccaagttct ttttttaatt tccaagtaac tgaaagttac ttttgttatt
    10801 taacatttag gtcaatttta gacagttttt gttcaaaaag cgatatttat agtggacggt
    10861 attactgcta tattaaggat ataaaatgaa agcgtttaaa aaggtggcgt aaagatgatt
    10921 attaaagaag agatttttgt acctaaagaa ttagtgaaag aaaaaattga cctgctcgtt
    10981 gaaaacctga caacgatcaa agacgataat ggtgaatttt tgttggactt tgatggactg
    11041 aaagtagatg acaaaagctg gacagtgtgg aattggccac aaggtgtcgg tctatatggt
    11101 atttataaaa attaccagat gacaaaaaat cctcgcgctt atcaagtggt caatgaatgg
    11161 tttgaggatc gtatggaaga aggcgctccg cccaaaaacg tcaatacaat ggcaccgcta
    11221 ttgactatgg cttacttgta tgaagacacg aaagattcac gctatttgcc ttatttagaa
    11281 caatgggcag aatgggtcat gaatgacatg cctcggacaa atgaagacgg gttacagcat
    11341 gccacatatg gaccggaaaa taagaatcag ttgtgggacg atacattgat gatgacagtg
    11401 cttcctttgg caaaaatcgg gaaactgttg aatcgcccag aatatttaga agaagctcgt
    11461 taccagttta tgatccatat caaatacttg atggataaac gaacaggatt gtggtatcac
    11521 ggctggacgt ttgaaggaaa tcataactat gccgaagcat tttgggctcg tggaaactgc
    11581 tggttgacga ttgctattcc agagatcatt gaaatcttag aattatcgaa agaagatgca
    11641 ttgcgcaaat tattgatcga aacacttgaa gcacaagtgc gtgcattaaa aacttatcag
    11701 tctgaaagcg gtttatggca tacgttgttg gatgatcctt cttcttacgt agaatcttct
    11761 gcaactgcag gatttgctta cggtattttg aaagcggtcc ataaacgtta tttaccacaa
    11821 gaatataaag aagtcgctta tcgtgctatc caaggattgc ttgaacaaat cgatgaaaaa
    11881 ggagaagttc aaaacgtttc aatcgggaca ggaatggggg acagtttaga tttttatcgg
    11941 aatatcggaa tcacagcaat gccttatgga cagtcgttaa cggtgctttg tttgacagaa
    12001 ttgctcgtct cttattgtta aaagaaagga aacccatatg aaaaaaacat cactgctgtt
    12061 tgcagcaagt tcgcttagcc taggtctgct aggtctaagc ggctgcggaa ataattctag
    12121 tgtggcaact gtcgcagatg cagatgtaaa tgagatagtt accttgcgct ttgcttatgc
    12181 aagcaacagc cagccagtaa ttgatgcaat gaatgaattt gggcgtttag taaaagaaaa
    12241 aacagatggt tccgtacaga tccagtattt cccagatgga caactgggtg gagaacgtga
    12301 actgatcgaa ttgacacagt caggagcagt agatttcaca aaagtaagtg cctcagcgtt
    12361 ggaaagtttc tctaaagatt attcgatttt ttcagttcct tatctattca atgatgaaga
    12421 acatttcttt aaggtgatgg ataatgaaga aataatggag ccaatctacc aatcgaccaa
    12481 aaatttagga tttaccggat tgacctatta tgattctggt cagcgcagct tttatatggt
    12541 agacggtccg atccatacgc cggaagattt gaagggaaag aagatccgtg tgatgcaaag
    12601 cgaaaccgct atcaaaatgg tagagctttt aggcggttcg cccgtaccta tgggaagtga
    12661 tgaagtgtac acgtctcttc aatccaattt gatcaacgga tcagaaaaca atgaatttgt
    12721 cttgtataca gctggacatg gtggtgtggc taaatactat tcctatgatg agcatacacg
    12781 tgtgccagat atcatcatca tgaatgatgc catcaaagaa cagctaactg atgagcagga
    12841 aaaagccatt gaagaagcag cgaaagaatc aacggttttt gaaattgaag cttttgcaaa
    12901 agcaattgaa gaagaaaaag ctttagcaca agaagaacat ggagtccaat tcaatgatgt
    12961 agataataca ccgtttcgag aggcagttgc cccacttcat gatatattca aaaacgatcc
    13021 tacctacaaa gacctttatc aaaagatcca agagcaagga gcgtagctgt gatgaaaatg
    13081 attttaaaca aggtattaga gatcctggga gctgttttgc ttgttgggat ggtcgctgtt
    13141 gttttatggc aagtattttc cagaacggtt ttaggaaatc caaatacggt cacggaagag
    13201 cttgttcgat tcggtcttgt ctggtttgcc atgttgtctt ccgcgtatgt tgtgggacaa
    13261 aaagcacatt tagccgtaac ggttttaagt gaaaaattaa ctggcaaaaa aagtaaaatt
    13321 ttagaagttg ttgttcaaag tttatttctg gtatttgctg cgatgatcat ggtgtatggc
    13381 ggatggaatg ctgtcacatt gacaatgggg cagatctcgc cttctttaag tattcctatg
    13441 ggatatgttt atctgtcagt acctgtatcg ggggtactca tcattatcta tagcctgatc
    13501 aatctaatcg atacattaag caacaagcca gcaattcaag aaaaaatata aaaatggagg
    13561 aataaaatgg caatagaagc cggattagtg ttattttttg tatttgttgt gttgcttgta
    13621 ttagggatgc cgattgctat aagtattgca ttctcatcga tgatgacttt attgttagtt
    13681 ataccgtttg atgtttctgc ttttagttca gctcaaaaaa tggtgggaag tatcaatagt
    13741 ttttcgctga tcgctattcc gtttttcgtt ctctcgggca ttatcatgaa taatggaggg
    13801 atagctaaga aactagtgga ttttgcgatg ttgttcgtcg ggcgcgtgcc gggggctttg
    13861 gctcatacga atgtgttagg gaatgcttta tttggttcca tctctagctc ggccattgcc
    13921 gcttctaccg cgattggcgg agtgttgatc cctcagcaag tggaagaagg atatgaccgg
    13981 aagtttgcga cagcggtcaa tatcgcgtca gctccgacag gtatggtcat tcctccaagt
    14041 actgctttta tcatgtattc acttgttgct ggtggtgctt cgatctctgc tttgtttatg
    14101 ggaggttatc tcgtaggcgc tttgtgggcg ctaggaatca tgctagtagc attcatcgtt
    14161 gctaaaaaga ataaataccc tgttgtcgaa aaaggacaga tggctcatgc tggaaaaata
    14221 ataaaagagg cgattcctag ccttctattg attgtcatca ttatcggtgg tatcttgacg
    14281 gggatattta cagcagtaga agcttcagcg atagctgtca tttactccct gttgattgct
    14341 atgttttact ataaaacggt aaaactaaaa gatataccta atatgttgtt tcaatcagta
    14401 gcaatgtcag ggacgatcat gttcttattg gctacttctt ccatgatgtc tttcgccatg
    14461 gcgtttaccg gtattcctca ggcaattagt tcgttgatta tgggcgtaac ggataataaa
    14521 tttattattc tgttattagt caatcttgtg ttattactgg tgggtatgtt tatggatgtg
    14581 gcgcctgcta tcttgatttt tacaccaata tttttaccaa tcgtcacaag tgtaggggtt
    14641 gatcctgtac attacgggtt gttttcaatc atgaatctgt gtgtaggctc catcacgccg
    14701 ccagtaggta caggactata tgtcggtgca agtgtaggag gcgtaaaagc agaggcaatg
    14761 ctgaaaccgc ttcttccttt ttatggggtt atcttagtcg tcttgttttt gattacttac
    14821 ttcccgcaaa tcgtcatgtg gctacccaat atgctgagtt aggagaatag ttatgttgaa
    14881 cattacaatt agaggacatg atctttccga agtccaaacg atagaagatc ttgcagaaaa
    14941 aacaaaagaa caagggattc atacactgca gctcgcctta ggtctttcgt ttcctgaaat
    15001 accttctggc gcaaatgaga tcaattctgg gatgggaaat tatgtcaaac gagttttaga
    15061 aaagcaagaa gtgaccgtag gaattttaag ttgctatatc aatatgattc atccagattt
    15121 aacgatacga caagagttgc tgacaaagtt cgagcagtat cttcgctatg cttcttcctt
    15181 tggtgcgtcg atggttgctt cggaaactgg atgtgttttg ccggaaatcc aatatacgga
    15241 agaaaatttc acagatgaag catttgctga agctgtgtcc gttatccgtc gcttggtaaa
    15301 agctggagaa aaataccaaa tgatggtggg gatagaacca ggtttgaatc atccggtgta
    15361 ttctttagca agggtagagc agctgatcca agcagtagat tcggactatc taggaatcat
    15421 tttagatccg accaatttga tcacaagtag tgattatcaa gaacaagtcc aattggtaga
    15481 agaagctttt gaacgttttg gtgaaaagat atgtgcggtt catttgaaag attttcgtgt
    15541 cgaacaggaa aaaatcgtgc cggtaaattt gggagacggt gtgatcgagt acacaaaaat
    15601 caaagaaatc atcatgaaga atcgtccgta cctgtatgtg gttcttgaag aaacaaaaga
    15661 tgatgggatt cgttatggaa gaagtcttct tgaataatgt aaagaagacg ttggttaact
    15721 aatatttaga atggaggggg cggggctaga agatgccacg tctcttcttt tttataagag
    15781 tatataaaag cagctctttt tgattacaaa aaacgtggta taataaaatt gtgcataagt
    15841 gaacaaaagg aggtgcggca catgctccaa aagaaaatca gcggtgaaca agtcaatacg
    15901 atggtttctg atcagtatga aatctatcat gtcaaagatg tcgtcagcca aaataaaacg
    15961 atctatcatc atcatgattt ctatgagatc catgctacat taaagggaga agcgactttt
    16021 tatttgaacg gacgacaatt tacgatcaaa gcaggaagtg tgctgctcat ccattccaat
    16081 gatttgcatc gtatcgtccg ccaatcttca gatgtattcg agcgtgtcta tatctttgtc
    16141 accccttctt ttctagaaag tcgttccacg ccatggtcta atctatcggc ttgttttcaa
    16201 ccaatgggag agaagaggag tcgtgtattg caaatagaac aggaagtatt gaagcaaaaa
    16261 ttatcattta tcgaccatcc tcctgataaa aaaatttacg gtgaagacat aaaatatgaa
    16321 caagctctgg tagaatactt gatttttctc aatcaagttg tacaaaaaga agagagtgcg
    16381 caagaacaga atgctgtagt tcctaatgag cgtgtggaac aaatgttaca atatatctca
    16441 aaaaatttat ctcatccgct ttctttagag gaaatggaaa agcagttttt tgtcagcaaa
    16501 taccatatca cacgagaatt taaaaagtac actggattta cgtttcatca gtatgtaatg
    16561 aagaaaaagc tgatctatgc caagcacttg ttgcgagaat accgcagctc tagtgctgta
    16621 tatagtaaaa gtggtttttc ttcttatccg cattttctga aagcattcaa gagagagttc
    16681 ggcataacgc ctaaagaatt tttgaaacgt gatacacaga aacagttggt tcattatgaa
    16741 cattttgaag atgaacaatg agaatgatca ctaaaaaata accgcagtag ctgctgttgt
    16801 ttacatagaa gcagaaactg cggttatttt atttttatct atatatttca aaatattttg
    16861 aaaaaatgac gtacatatta tatgaatcag ctgaatttac gaaagtctct cggcgatagt
    16921 cctgtttttg ctttgaacag gcggctaaag taagcaaaat tctcaatccc tatttcttcg
    16981 gaaatcattc gaaccgtaaa ttctgtatac cgaagaaggt ctttagcgta agaaagtttt
    17041 ttgctgatca aataatcgat tggtggagaa ccgataaatt tggaaaaatc tttgctcagc
    17101 tgatatttat tcaataagaa ttgttgttct aattgatcaa gtgtaatcgt ttctttgaaa
    17161 tgttcgtcta agtattgctt cagtttgtaa acgtaggcgg gaatatcctc ttcttcgaaa
    17221 tctagctgat acttttgcaa aatcagttca ttcagcaact cgtggatagc tacagaggac
    17281 tggaaatcgg tacgggcatt cgtgccttgt tgcatgtgga tcaattctgt gatcaaatgg
    17341 tggatcttgt tttctgatgg atctcctgtt gaatggaagg tgttatggcc gtcttttgtg
    17401 aactcctgat aaaatgattg gacgttctga ccattcaaat ggatccaatc catttcccat
    17461 ggttcttcgc tgatcgtttg ataacgctga tattcttggc agtcaataaa aaataagtct
    17521 ccagctttta gctgttgctg attatcatta tatgtaagcg aacctttgcc agacaaagta
    17581 aactttatca agtaagaagg taaatgtgct cgttcagtat agtaagggat tggtgctttg
    17641 aagtaaccga tttcttggat ataaaaaaat aaattcctgc ttctttgtgt aggcgtcaag
    17701 atcactcttt ttgagtcttc cgaccatgag tggttggctt tttcccagta atccatgtaa
    17761 acactcccaa cttgtcaaga taatgcaatt atataccaaa atagtgtgaa gcaaaatata
    17821 agattctgta ttatgatagc attgtcaata aatgataacg ctttattaat aaagtgctaa
    17881 tcaacaataa agtaaaagag gtggagaaat gaatccaaca tttgttgcca tcgatatcgg
    17941 tgcatcaagc ggacgactaa tgaaaagtac gagggatgca aaaggttctt tgatcttgga
    18001 agaagtacac cggttcaaaa acggctttcg gaacaaagac ggtcacgatc gctggaagat
    18061 cgattatctt atcaaagaga ttttgattgg atttgaaaaa ttaaagcaga cagggattga
    18121 tcgccttttt gcggggatcg atacatgggc agtcgattac tgtctgattg atgaacaagg
    18181 ggatcggata aatgatccga ttgcttatcg ggacaagcgt accaatggag cagtagaaca
    18241 gttttctgaa atctattctc tagataagtt gtatgagcag acagggattc agatccagcc
    18301 tttcaatacc ttgttccaat tgtttgctga agaaaaagaa aatttggcaa aagcacataa
    18361 attgttactg atacctgatt atttagggta tgtctttact ggtaacatgg tgacggagaa
    18421 aactaatgca tctactatgc agctgctgaa tgcagggaca aaagaatggg aaatagaact
    18481 tcttgaaaaa atcggtgtct cgaaggaatt atttccacca ttgacagagc cgggaacgat
    18541 actaggagat ctgcaaaaag aacaattttc aaaatatgat ttgccagatg tgacctttat
    18601 cacagtagca agtcatgata cggcgtcagc tgtattagga acgccaggtc aaggagaacg
    18661 ttggggttat atcagcagtg ggacatggtc gcttttaggg attgaaacaa agatcgccaa
    18721 tgtttctcgc aatgcttttt ctgaaaatta tacgaatgaa tggggtgccc ataacacggt
    18781 gcgttttttg aaaaacatca tggggatgtg gttgatccag gaagttgccc gaatgcaaga
    18841 gtacgagtac agttatgcgg aattggcaga gcttgctgca aaagaaaaac cgctgcagca
    18901 agtgatggaa atcaatgacc ctcgattttt gaatccccca aatatgatag aagagattca
    18961 gcaatactgt tttgaaacag agcagccagt ccctgtctca tcgggagcta tcgctcgttg
    19021 tgtgtatgat aatcttgctc tttgttacgc acaagagctg atcaaagtag aacacttaac
    19081 tggaacgaaa ttggaaaagc tgcacatcgt agggggcgga tcgaataatc gtctactgaa
    19141 tcaattgaca gcagattatg ccggaatcat tgtagaagca ggacctagtg aagccacagc
    19201 aatcgggaat gttgccatgc aaatgctcag tacaggtcag ttttcgaata tagaacaagc
    19261 aagaaatgta atcaaacagt cgtttccatg tgaaactttt tacccagatg aaaataagca
    19321 aaacacgatg gaatggtacg tgaataaaat caaaggagta atcgtatgaa cacgattgaa
    19381 agaaattacg aacaagcaaa agaaaaatat gcaactatcg gtgtagatac agatgctgta
    19441 ctagaaaaga tacaggacat caaaatttct atgcattgct ggcaaggaga tgatgtcaaa
    19501 ggtttcttga caccggatgg cgaattgacc ggtggaatca tggcgacagg gaattttcca
    19561 ggagccgcac gaacacctga agagcttaga caagatctgg agaaggctta ttcgttgata
    19621 ccgggcaaac acaaattgaa ccttcatgct atctatttgg atacagaaga atctgtcgat
    19681 ctaaatgaaa ttgagccgaa acattttgaa aaatgggtag agtgggcaaa aaaagaagaa
    19741 atcggtcttg acttcaatcc gactttcttt tcgcatccaa tgatgaaaga cggctttaca
    19801 ttggctcatc cagataaaga agttcgtgaa tactggatcg aacacgggaa aagaagccgc
    19861 aaaatcgcgg agtactttgg gaaagaaact gggcaaacaa gtatcaataa cttttgggta
    19921 cctgatggga tgaaagataa tccgattgat cgttttaccc cacgggaacg tttaatggaa
    19981 tcactcgatg aaatttttac agaagagtta gatgaacggt atgtacaaga tgcagtagaa
    20041 agcaaactat ttggtttagg cgctgaagct tatacagtcg gttcccatga attttatatg
    20101 ggttacgggt tgactcgtga caaacttgtt tgtctagatg ctggacattt tcatccaaca
    20161 gaagtgattt ccaataaatt atcttcatta gctttattca gcaaaggaat catgttgcat
    20221 gtttcccgtc cagtgcgttg ggattcagac catgtggttt tgatggatga tgaattgcag
    20281 gaaatcgcta aagaattagt ccgtaacgaa ttgttggaaa aaacaaatat cggtctggat
    20341 ttctttgatg caacgatcaa ccgtatcgct gcttgggtca tcggtacgag aaatacacaa
    20401 aaagcactgc tgaaagctat gctggaacca gttgagcgat tgaaagaaat ggagctggct
    20461 tttgacttta cttcaagaat ggcttatacg gaagaattga aagatttccc gtatgccgat
    20521 gtatggaatt atttctgtta caaaaatcaa gttccagttg gtttggattg gctggaagaa
    20581 gtccaggaat atcaaaaaga cgtgttggaa ttaagaaaat aggagtgtgg ctatattgaa
    20641 aaaaatagat attttacaag cgccttatgt gaaagaaatg atcgaaacga cgtcgaatct
    20701 ttatcgcttg ggatgggatg aaagaaatgg cgggaatatt tcttatttac taaaagaaga
    20761 agagatcaca ccgttcttgg atcctgaaaa agtgatccgc cgcatctcga tgatttttga
    20821 tgccagccgt ttagcaggat gctattttat tgtaactggt tcaggaagat attttaaaaa
    20881 tgtagcgagc gaacctgccg agaatcttgg aatcgttcga gttgctgaag atggcaaaac
    20941 actggaactt ttgtgggggc tggaaaacga atgccttcct acaagcgagt tgccaagtca
    21001 tttcatgagt catatcgccc gtttagaagt agacccagat aatcggatcg ttatgcattg
    21061 ccatgctagt catctattag cgatgagttt tacgcatgaa ttagacgaac gttcctttag
    21121 tcgtacgcta tggcaaatgt gtacggaatg cttagttgtt tttccagaag gaatttccat
    21181 cattccgtgg atggttccgg gaacaaatga gattggggaa gcaacagctg aaaaaatgaa
    21241 agaaactcga ttggttttat ggccacaaca tggaatctac gggtcaggaa aagacatgga
    21301 tgaagtcttt ggtttgatcg agacagcaga aaaggcagca gaagtctata cgtacgtcaa
    21361 agcgcaagga ccaatcttgc aaacaatcac ggacgaaaac ctgtggcatt tagcagatgc
    21421 gtttggtgtc actccaaaag caggttattt ggaggaagtt catacgaaag caggtgtctg
    21481 acatggtgaa aaaagctttt tgcatgaaag tttacccaga aaaacaagaa gaatacaaaa
    21541 aaagacatga tgaactttgg ccagaaatgc gtacagcact tcgtgaacac ggggtcatcg
    21601 actattcgat ctatcttgat ccgagtacaa gtttgttatt tggttactta gtgatcgaag
    21661 atgaaaagtt atgggaaaaa atggcaaata catctatcaa tcaaaaatgg tggaagtaca
    21721 tggaagatat catggagaca aatccagatg cctctccagt cagttgggaa ttgatgccag
    21781 tctttgaact gtagcaacaa gcaactgggc aaccggttgc ttggggttct ttcgttttta
    21841 ttgtgaaaaa taatacaaat taggaggaat agaaaatgag taatcgaatg attttaaatg
    21901 aaacatcgta ttttggaaaa ggagcgattg agtcgatcgt ccctgaattt cagcagcgag
    21961 gattcggcaa agcagctgtc attactgaca aaggattgat cgagcacggt atagcaacaa
    22021 aagtaacaga acttctagat aaagcagcaa tcgcttatgc tttatacgac gggatcgtac
    22081 ctaatccaac gatccaaaat gtaaaagatg gagtggcttt tgttaaagag gcagaggcag
    22141 actgtttgat cgcaatcggt ggaggttcgc caatcgatac ggcaaaagcc attgggatta
    22201 ttttgacgaa tccagagttt tcagacgtca ttagtttaga aggtgttgct gatacgaaaa
    22261 atccatgttt acctatatta gctataccaa cgacttctgg aacagcagca gaagtaacga
    22321 tcaactacgt catcacagat gaagtaaatc accgaaaatt tgtttgtgtt gatcctcatg
    22381 atatcccaat cgtcgcgttc atcgacagcg atatgatgat gggaatgccg aaaaaattgg
    22441 ctgcatcaac aggtatggat gctatgacgc atgctattga agggtttatc acaaaaggcg
    22501 cttgggaaat gactgatatg ctgcatttaa aagcaatcga aatcatcggc cattctttgg
    22561 aagcttctgt agatggcgat caaaatgggc gagaaaaaat ggcattagga cagtatattg
    22621 cgggaatggg cttctcaaat gtcggtttag gactggtaca cgggatggct cacccgttaa
    22681 gtgcatggta caacattcct catggcgtag cgtgtgcagc acttttgcca actgtcatga
    22741 aatataacaa agaatatact ggagaaaagt accgtgagat cgctcttgtt ctagggatta
    22801 aaggagcagc tgaaatgtct ttagaagatg taagagaagc ggcttgtggt gagatcgatc
    22861 ggttgagcaa agcggttgga atcccagaaa ccatttctga attaggtgta aaagaagcag
    22921 atattccagc aattgcagaa gatgctttgc gagatgtatg cacaccagga aatccaagag
    22981 aaacgacagt agaagaaatc attgctttat atcaaagttt gatgtaaaaa cgaagcggat
    23041 cttcaacatt aaattgcctg taaagagaaa tggtagttta tatctggata tctcttttaa
    23101 attgatggta tttccgctat aatttttctt ataaagaaat aggagaatat tatatggaaa
    23161 ataaaaagcc ttatggaact gtattgatca aagcctctaa aatactagac tatttagcgg
    23221 aaaaccaaga tgtctctttg cagacgatcg caaagggtgt gggaatgacc tcttctacag
    23281 tcttgaaaat actagatact ttgttgatga tcggctacgt aaataaaaat tcagagaaaa
    23341 actatcgttt aggtgcaaag cttattcgct acgcgaataa aaacattgaa caaatcgatt
    23401 tggtagagtt gactttaccg tttttagaac agctgcagca aaagatcgat gagactatcc
    23461 acttaggggt attggacaac aatgagatct tgtacgtgaa caaactagat ccaaaacatc
    23521 aaacgatccg catgtcttca aaaatcggaa tcacccgacc attatacaat tctgcgatgg
    23581 gcaaagccgt attagcagaa ttcagtgaag agcagtacac tgattatctt gaaaagcatc
    23641 cgttgatccc ttacacagaa tatacgatca ccaatgcatt acggttgaaa aaggaaatca
    23701 aaacggtaaa agaaacccac atcgcatttg acgatgaaga aatcgaacgt gatatttttt
    23761 gtataggagc ctcaatcgtg aaaaacgaac aaatcattgg tgcatttagt gtaagtatgc
    23821 cgaaatatcg tttaacagat gagacaaaag aacaaataat cagtgccctc aagcaaacaa
    23881 aaagcgaaat cgagcaaaga attcaaaaat aatgaaaaaa gcgtttgcaa tttttctttt
    23941 ctgccgtata atatgggtat agatttccaa gttataaaat aaaatttcta aataggaaat
    24001 aggtggagaa gatgaaaaaa attgatattt tatctcgatt gaaaaacgcc ggagtgattg
    24061 cggtggtacg cggaaaaagc aaagaagaag ctttgaatgc ttgccacgca atcatcaaag
    24121 gtggtctaac tggtattgag ttgactttta cagtccctca agcagatcaa gtaatcaaag
    24181 aacttttgtc attctacaaa gaccaaccag aaatagtgat tggcgcaggc acagtattag
    24241 acgctgtcac agctcgcttg gctatcttag ctggcgcaga gtatattgtt agcccttcct
    24301 ttgatcaaga aacggcagag atgtgcaatc tgtatcaaat tccttactta ccaggatgta
    24361 tgactattac cgagatcaaa acagcgctga aaagcggggt agatatcgtc aaactatttc
    24421 ctggaagcgc ttatggacca agtatcattt ctgccttcaa ggcgccgatg cctcaagtca
    24481 atatcatgcc aactggcggt gtgagtctgg acaatatgaa agagtggttc gatgctggtg
    24541 tcgtaacagt cggagtaggt gggaaccttt tagcacccgc agctacagga gattttgaca
    24601 aagtaacgga agtcgcgcaa cagtatgcag caaaaatgaa agaaatcaag aggtagctgc
    24661 ttatgggaaa agtagtgaca ctcggagaaa tcatgttgcg attgtccaca gagcagggaa
    24721 cccgtatcga ttcaagtgaa cgattcgctg cccattatgg cggaggggaa gcaaacgtag
    24781 caatttcttt agctaattac ggacatgaag cgatttttgc tacaaaagta cctgataacg
    24841 cattgggaaa agcagtcaaa aagcacttgc aatgttatgg agtagatacg aaacaggtat
    24901 tatctggtgg atcaagacta ggtacttatt atatggaaac tggtagtggc gaacgcgccg
    24961 cctcagtgat ctatgatcgt gccggatcaa gttttgctga aatggatcat ttggaatggt
    25021 cgctagagga gttattccaa ggaatagata tatttcatgt ttcaggaatc accccagctt
    25081 tgtctaaaaa atggcaaaaa atgacgaaac aggtgataga agctgcaaaa aaagctggct
    25141 gcctgatcag cttcgatatc aactatcgtg gaaaattatg gacacagcaa gaagccagcg
    25201 aagtaatcca tcagctttta cctttagtag atatctgctc agctggaaaa atggatgctc
    25261 tttatttgtt aggtatcgag aaagcgccag aagcagaaga acaacctcta atttattatt
    25321 atcaaaaaat gcaggaaaag ttcccgaata ttcaggtgtt ttattcgacc aagcgtaccg
    25381 ttcattcagc aagtgaaaat gaattgaagg ggacattgtg gatgaaccat gaatatgtgg
    25441 aatcccaagt ccatagaatc accccaatcg tggatcgagt aggtggcgga gatgcttttg
    25501 caggtggcgt gctccatggg attttatcca atatgtctcc gcaagaaatc attgattttg
    25561 ctacggcagc ttctgccttg aagcatacga tccatgggga ctgcaaccaa tttagtcaag
    25621 aagaagtcgc acaattttta gcatgcggct ctggaaaaat cattcgatag aaggagtaga
    25681 agaaaatgca agaaatggaa acacgttata cacacagtcc agaagatatc cgtcattatt
    25741 caacggaaca attgagaaaa gaatttttag tagaaaaggt atttgaacca gggaaaatca
    25801 gtttgactta tacgcacaac gatcgaatga tctttggtgg agtgacacct actgaaaaag
    25861 aattagaaat cacattagac aaagaactag gtgttgatta cttcttagag cgtcgtgaac
    25921 taggtgtgat caatatcggt ggaccaggat tcatcgagat cgatgggcaa aaagaagaaa
    25981 tgaaaaaaca agacggatac tatatcggaa aagaaacacg acatgttgta ttttcttctc
    26041 aagatgctga aaacccagct aaattctata ttagttctgt tccagctcat cataaatatc
    26101 caaatgtaaa aatcagtatc gaccaagtaa aaccaatgga gactggtgaa ggcctgacac
    26161 tgaatgaacg taaaatctac caatacatcc atccaaatgt atgcgaaagc tgtcaattac
    26221 aaatgggtta tacgatttta gaaccaggaa gcgcttggaa tacgatgcct tgtcatacac
    26281 atgaacgtcg tatggaagct tatgtctact ttgattatgc caatgaagat acacgtgtgt
    26341 tccacatgat gggcaaacca gatgaaacaa aacatttagt tgtagacaat gaacaagcca
    26401 ttatttcgcc aagctggtcg atccattcag gtgtaggtac aagcaattac tcattcatct
    26461 gggcaatgtg cggagaaaat atcacctata cagacatgga tatggtgcaa atggatcaat
    26521 taaaataagc ataagggaga gaaaatgatg gaatttagta tggatatgtt tcgtttagat
    26581 ggaaaagtag cattagtcac cggtgctgtc tatggtattg gatttgagat tgcacgctct
    26641 ttagctacag caggagcaaa aatcgtattt aataacttga atcaagaatc agttgatgaa
    26701 ggtatagcgc attataaaga agcaggcatc gatgcaaaag gttatgtctg cgatgtgacc
    26761 gatgaagaag cggttcaagc gatggttcaa cagatcaaag aagatgtagg ttcagttgat
    26821 attctagtca acaatgcagg gatcatcaaa cggacaccga tgatcgaaat ggatgcggca
    26881 gacttccgcc aagtaatcga cgtggattta aatgccccat tcatcgtttc aaaagcagtt
    26941 attccggata tgatcgaaaa aggcggcggt aaaatcatca atatctgctc catgatgagt
    27001 gaattaggac gcgaaacggt cagtgcttat gctgcggcaa aaggcggatt aaaaatgctg
    27061 acgaaaaaca tcgcttctga atacggtcaa tacaatatcc aatgtaatgg aattggacca
    27121 ggttatattg ctacaccgca aactgctcca ttacgcgaaa cacaagaaaa cggtgaacgt
    27181 catccattcg atcaatttat cgttggacgt acgccagcag cacgctgggg cgagccaatc
    27241 gatttggctg gaccatctgt cttcttggct tctagcgcat ctgatttcgt taacggccat
    27301 gtcttgtatg tggacggagg catacttgcc tatatcggaa aacaacctta aaagagcttt
    27361 agtacactgt ttagtggaga ggttgtgaaa tcagcggatt gaacgaatac cgaaggacag
    27421 ctgattaaac atcatttatt cgaaaaaaga ggctgggaca gaagcattta actccaagaa
    27481 ataagaagga attcacgaaa attgcttttc aaatttttgt gaatttcagc ttatttccga
    27541 aggagttgct tttacttccg ccgtttgtac gtgtttagag cgtgagacaa aagtgttctt
    27601 tacttttgtc ccacgctctt ttctgtgcgt cttccatact tcactaagtc gatccctctt
    27661 gcttcgcacc aatccttcac tggtccggaa aagatcagag attgttggtg tagggccgcg
    27721 gtattcgttg cgccgaccat agtataaagc agacgaagct cttcttgcca ttgcttcatc
    27781 agtataatag tttcttctac gccgtgattc atcagatgcg tcagtacggt tcctgaagta
    27841 cccacggcat ttgcgccgag acaaagggct ttaaatatgt cataggcatt gcggatacct
    27901 ccggaggcta ggatttccat agaagtgtct gcttcatttg cttcaagcaa tgaagagact
    27961 gtcgattgcc cccagtcagc taaataactc agttcccgct tggagcgacg ggcgttttcg
    28021 atctgggtga agcttgttcc gcttcgaccg ctgatatcaa ctgtatgaac tcctaaagca
    28081 gctagatcat tgagcgtttc tcttgtcatg ccaaaaccga cttcttttac gatgaggggg
    28141 acgtcaatgg ctgtttgagt ttcttgaata agtactttcc aattggtaaa atcacggtct
    28201 ccctcaggca taaccaactc ttgaggtgca ttcaaatgaa tctgtaaggc atctgcgtga
    28261 aacaatcgga tagcttcttt ggctctttcg acagaagtcc ctgcaccgat gttggcaatg
    28321 attttcccgt gaggatattc ttgtcgcata atcgtataag tatcggctaa agaagggact
    28381 ttcaaggcag cgctgactga accagtggca atcatcaaat ctgcttctct tgcgacgatt
    28441 gcaagatctt ggttgatttt ttttgttttt tcgcttccgc cagtcatcgc attgatataa
    28501 aatgggctgc ttagtgtaaa cccaactgcc tgtgtactta gatcgacatc agaaactgct
    28561 atttgcggca aagggttatg gatgatccgt acgaagtcaa attcgttttt ttgtttatca
    28621 tgaaaggctt tagctagtga aacatgttcg tcttttcgat tcatcggttt tcctttcttt
    28681 gatcgctata gacatgtaac ggcagtggag tgatttctgc tttttcccat gcactcatta
    28741 aaggaagaat gccagatttc tggtcaacaa ttacgattcc gcaatcgccc ccacctgcac
    28801 cagaagattt tgcggctcct tcatactgtt cagctaaatt acacaatttg ttcaaagcag
    28861 gcgtttcgat gacgacccca gtgattgcag ataaatcatg cagtaattgt cggttttttc
    28921 gaatcatctg ttggatcaac gttacattat tttctttaaa ccctttgatc atttcgttga
    28981 cacattctgt actatttttt aagaaaagct gataagccac cattttatct tctctcgaac
    29041 ggtgaacttg atcgaccaaa tcagaagtag aggcagggct acccgtccaa ccaatcaata
    29101 aacgtaaatc ttcaggagca atcaatggct caatggatag acctggccaa tccagggcaa
    29161 gtaactcact gatagaatgc tgagtttctt gttcttggag ccaaggatgg tcgaaggttg
    29221 agaaagcgat ccagccacca taacagctag cagcgatgtc gccgcaggaa ccattatctt
    29281 gaactgctaa attggctagt gctgcaatct tgaaaatctc caactgagat aaattcaacg
    29341 cgtaaaaaac attcaaggct ttgaccgttg caacggtcac ggcaccgcta gaacccaatc
    29401 catatttccg gccatttgaa ctgtctaact cacttgttac tttcagatca taaaaggata
    29461 aaagaatgtt tttttcttgt gcatactttt cagtcaagcg aatagcagca aggatataat
    29521 gaaaaggatt ttcccgaata tctaaaacta attctccgtt gcgtcttgtc caacgtacag
    29581 gcatcccact atattgtgca gattggatac ttccgacttt tcgtgcagat tctacagtga
    29641 ctgtcacgaa ttgatcgact gcagcgataa ctgctggatg gcctgtttca acaactgcat
    29701 attctccggc aatatagagt ttgcctggtg cagatacttc aatcataaaa atctcccttt
    29761 attcaataat cgcaattcct ggaccagcat gtgcagtaat tacttgttct ttgctaaata
    29821 atttggtaaa tgtttcttgt acctcagata aatggctgtt ttccactaaa actttgacat
    29881 tagggccagc atccatcgta aagtagcatg gaatgccttg ctttctcaat tgtcgcaccg
    29941 catccatcgc ttttaagctg tcaggagacc agtaagtgaa tggaggctgg gcagctaaag
    30001 tcgttccatg catttttagt ccgtttcttt ccatcgtttc tccgagaagt tggaaatctt
    30061 ttgttttgat tgcttgtttc aattgatata gatccccttc aacggaatct aaccagcctt
    30121 gataaaaact ggatgtttcg actgtccgac gcatcccatt tctgctggac acttcttttt
    30181 tctggtcgtt gatcaaaacg aaaaccattg ctaaatcgtc ttcgaaagaa tcggaaggga
    30241 ctggcttagc gtaagaactt aagtcgtcat ggcctttttc ccattcgacg aaaccaccga
    30301 aaatacttcg gcaagctgaa ccagacccgc gtcgagcaaa tcttgaaaga gagagatcat
    30361 ctaatccaag cttaagagca gtattgcaag cgcctgctaa agcagctagc ccgctggcag
    30421 aggaggctaa tccagctgcg gtaggaacga aattctgact gattactgaa gcttttagtg
    30481 agaggccggc ttctttacga aaaaggtcaa gaaactgact gacttttttt gttgcttttt
    30541 cgtcttgcaa ggtgccatct agataaaatt catctaccat atagctatca gaaaagatga
    30601 cttctgtctc tgtataaaat gcatccaatg ttaacgaaag gctgttgttc attggaagga
    30661 tgagttcttc atttttctta ccccaatatt tgattagagc aatgttggta tatgcgcgtg
    30721 ctttgccttt aaacataggt atgtactcct aatccttgta tccaagtttc agcagcaccc
    30781 gcatcttcaa gtgcttgact gatttcttgg gcttttgttt ttgtttgtgc taatgcaatc
    30841 atacagccac cgcgtccacc gccagttaat ttggcaccca atgccccggt atcttttgct
    30901 gtttggatca atagattaag aaaatcattg ctgattgtca gcttttccag aagtgattgt
    30961 gattcatcca ttgtctgtgc caacgtttct ggtgaatttt caatgattgc ttgttttgct
    31021 tgcttcgtca agtatcctaa tttttggatc atttgtccag tttcatgagg ctgggtttca
    31081 aagaggtgag cgacatcttt gacggcttct cttgtttgtc ctttgattcc tgtatcagcg
    31141 acaatcaaaa aagcatcgat gttcaaagaa aagtagtcga aaggatgccc ttttgtaaaa
    31201 taaatcggct gcaagctgct agtagcggct gcatcgattc cactaggatt accgtgggcg
    31261 attttttccg aaagctggac attttctaat agtatttcac gagacaaagg aaatgctaag
    31321 taatcataaa aagcacgagt gactgctgtg gcgactgcag cgcttgatcc cattccacgt
    31381 tcagcaggaa tcgtgctttc aatggtcagt tgcaagtttt tttggatgtc atgctgtttt
    31441 tttaagtgaa tgaataattt tttgatattt tttaatgcat gaggagcttc ggctaaattt
    31501 cctgaatagt aggaagaaac cagttgatcg tccattgcat ccagctcttc aaggaatgcg
    31561 gtgacttttg ttgcatagaa aggaaaggca atcgctggtt ctccataaac aaccgcgtgc
    31621 tcgcccatca atatgatctt tccgcttgat tctccttggc catagtttgc cataatctaa
    31681 ctccttctca cgtaaaagtg atttttaagc aaaaaataaa gcgcccaaaa cgagttgcgc
    31741 tgcttcacga atttttttgt ccactaaggg tctcaaaaaa cattcctcct ttattttact
    31801 aaaaccatct cagaagtaaa actaagaata cgttttctaa agaaaaaaca cttttttctt
    31861 aagaattttt tgactttttt tcttctttga ctagaaaaaa atacaattga cactactaga
    31921 tattgggggt atatttaaaa aggttggagt taaacacaat atttagtgat gaagtgagct
    31981 ggaggtaaat gagcgtgatc gttttagcag gtacaattgg tgccggaaaa tcaagtttaa
    32041 cagaaatgat ggctgaacac tttgatagtc aggcatttta tgaatcgatt gatgataatg
    32101 aagtcttgcc cttattttat gcaaaccctg aacagtatgc ttttttgctg caaatttatt
    32161 ttttgaataa acgttttgca agcatcaaac aagcaatgaa agatgacaat aatgtattgg
    32221 accgttcgat ttatgaagat tcactgcttt tccatctaaa tgcagatcta ggaagagcaa
    32281 cagaaacaga agttcgtgtg tatgatgaac tgctggaaaa catgatggaa gaacttccct
    32341 atgctgccca taaaaaacat ccggatttat tagttcatat tcgtgtatct tttgatacga
    32401 tgttggagcg tatcgaaaaa cgtggtcgtt cgtatgaaca attgtccttt gatccaagtc
    32461 tatacgatta ttacaaagaa ttgaacagac gttacgatca atggtatgaa gaatacaaag
    32521 aaagtccaaa aatccaaatc gatggagacc gctataattt tgtggaagat cctcaagcaa
    32581 aagaagaagt cttgaaaatg atcgaagaaa aattagcaga gattcgccaa accaaagtag
    32641 ccatttgatt tacagttgct caaataaagg gtaaaccttt atttgagcga cttttttctt
    32701 tatactggaa acaaatgtca ggaggataga gtatgcggga aaaacactat tttaatcaag
    32761 accgtaattt ttggatcaat gtacagcaaa acgatgtgct agctgttaaa aacttaaaag
    32821 aagaatatgg cattagtgac gagatgctga cttattctct agataaaaat gaacgggcgc
    32881 gcgtagagta cgattctttt gatgaagcgt tactgcttgt atcaaatgtt ccgcaccagc
    32941 aaaaagtcga taatcattat gaaactagtc ctatcgcttt tattttaaaa gaagacggtt
    33001 tgtttacatt taccacgccg aataccgagt acgtgattcg actaattcga tcgcttttgg
    33061 aacgaatgcc agacatgagt gtatacagtt tattgtttcg tacattgttt ttgatttctg
    33121 attccttttt tcctttaatc gaggaagtga atagtgaacg tcagcggctt aatctgaaat
    33181 taagagaaaa aacaacgaac aagaatctgc tgcaactttc agatttagag atcggtttgg
    33241 tttacttagt tacaggaaca aaacaaaatg tagtactttt agaacaaatc aaggcattgg
    33301 ctatttatcg caagttgtca gaaaaggaaa aagaagagtt ggacgatgcg ctgatcgaag
    33361 cacgacaagc agttgaaatg acgaacttag cttcgcagat tttagaccag ctctctggca
    33421 cttataataa tttgctgaat aacaacttga atgacacgat gaaatttttg acggtctggt
    33481 cgctgatctt gaccgttcca actattgtga caggattctt cggaatgaat ctccagttac
    33541 cctttaccca ttccgttttc ggatggggaa tcgccttgat catcagtttg gtcttatcta
    33601 tttggatgct tattgcactg tggcggcgga ttcgttgatc tagtctttga tctgcaaacc
    33661 aagggcttgg gcgatcacaa gtgcttgctc ttggttgacg attagtcccg ccaaagaatc
    33721 ttgagataaa gcgattgctg tgaagaaatt agtcgtaaag tctaatccct tcagagaagt
    33781 tcgaaaccag ttcgaaccgg tcaactgatt gtcagacaaa aaaaggtttt tccaagtgac
    33841 ctcataaaat tcgctgtctt ctaattgaca atgatcgaag gagacagctt tcaagtttgt
    33901 actactaaag gaagccatcg aagcaataca atcagtgaaa gtacagtctc gaagataact
    33961 ttcggcaaaa ttcgtacctg ttaatttaca ttgatgaaac acgacttggt ggaaactgcc
    34021 accaatccac tccagattgg aaaaatcaca tttttcaaaa atgacattac tgcattcaaa
    34081 atgacgtaaa actgtttttt gcatcgtaag tttttggata tgactctctc ttaataccat
    34141 atttttggca tcgagatagc tttggtcacc cccgttgatc agaagaccag agaagatctc
    34201 ctcatcttct aaataaaact ctccctttgt aagaagagga agagaaggtg gaataggttc
    34261 gatttttttc atgtgggttc acctcgtttt tctttagtat agcaaagaag cgggaatcac
    34321 tgctagaaag tctgctaatc taatcatttt cagaaaagga agacaaactg tatgaaaaac
    34381 attgacaaaa agattagttt ttgctatact gtgatggttg agaaataaaa gcagaagcac
    34441 ccgcttctcg ccttagttga taatgtcact gggctagata gttttcactg gttctattag
    34501 gtgaagtacg cgcgggttct gtaagagaac tcgttttttt attgccgttt attcggtaag
    34561 cttttctttc tctcataata tttggaggtg aatgaccata gcaaaggata tgatggttaa
    34621 cgacggcatt cgtgcacgag agttacgatt gatcggttca gatggtgagc aattaggagt
    34681 taagacaaaa gcagaagcat tgaatattgc agaacaagca aacttggatc ttgtgttagt
    34741 tgcccctggt gcgaaaccac cagttgcgcg aatcatggac tacggtaaat accgtttcga
    34801 acaacaaaag aaagaccgcg aagcgcgtaa aaaacaaaaa gtgatcaatg taaaagaagt
    34861 tcgcttaagt cctacgatcg acttgaatga cttcaataca aaacttcgta atgcacgtaa
    34921 gttcttggaa aagggcgata aagtgaaagc ttctatccgt ttcaaaggcc gtgccattac
    34981 ccataaagaa attggtcaaa aagtcttgaa tcgcttagct gaagaaactg cggatattgc
    35041 aacagtggaa caaaaagcga aaatggacgg acgcagcatg ttcttgacgc tggcaccgaa
    35101 aaacgacagt aagtaatttg aatgactaac tggctgttgg acagccgata gtcggataac
    35161 gaaagatttt gaggaggaaa tatagtcatg ccaaaacaaa aaacacaccg cggatcagca
    35221 aaacgtttca aacgtactgg taaaggcgga ttgaaacgct tccgcgcgtt tacaagtcac
    35281 cgtttccacg gcaaaacaaa aaaacaacgc cgtcaattgc gtaaagcaag catggtttct
    35341 agtggcgact tcaaacgtat tcgccaacaa ctagcaaaaa tgaaataaga agtacaaata
    35401 acagaatctg aagatttatt tttattagga ggaattatac atggcacgtg ttaaaggtgg
    35461 aacagtaact cgtaaacgtc gtaaaagagt gctaaaatta gcaaaaggtt actacggttc
    35521 aaaacacact ttatttaaaa cagcaaaaga acaagtaatg aattcataca actacgcata
    35581 tcgcgatcgt cgtcaaaaga aacgcgactt ccgtaaattg tggattgctc gtatcaacgc
    35641 agcagctcgt atgaatggct tgagctactc aaaattaatg cacggtttga aagttgctga
    35701 aatcgacatc aaccgtaaaa tgttagctga cttggctgtt aacgatgcag cagcatttac
    35761 tgcattggct gaccaagcaa aagaagcttt ggctaaataa gctaaacaat tataaagagg
    35821 aaagaagata acgaaaagtt atgttctttc ctcttttttt atttacaatc ctccatcaaa
    35881 tgaaacagga caataacgta taagtctaaa atagcataat taaggttttt taattgaaaa
    35941 ctgaacattt atggtcaccc tttaatgaaa gcgctaacta cataagttag aatgagtttg
    36001 actgatatat tagtttgctt atcagaaaaa caaaatggac ggaggaataa catgagtgat
    36061 attattattg gtattttgtt agttatctca ttctttttca tggtctggta ctgtgtaaaa
    36121 ggctacaact tgatggtcgg ctttgccatc atggctactg tatggatggg attagcgcta
    36181 gtcggaaaca cgttttcacc aaacccggcg atggaagggc aaggagtaat tgatgtgttg
    36241 acgcatatct atacgacggg gccagctgag tacgccaaat cgatcttggt aaatgtcttc
    36301 tttggtgcct ttttcgggcg tgttctagta gatagcggaa tcgcagctac cctgattcga
    36361 aaggtagttg aacttggagg ggacaagcca agaatcacga tgagcttact atgtattgta
    36421 accgctgtta tattcatgtc gatgacagga atcggaccag tgatttctat tgcagttatt
    36481 gtgttgccaa tcttgatgtc attaggtatt tcagtaccgg ttgcactgtt ctcatttatg
    36541 ggctcgatta tggctggaat ctttgctaat atcgtcaatt tcaaacaata tcaaacgatt
    36601 tatgctggtt tcaatccagc ggctgaaagc tatacttata atgactattt ccaaattggt
    36661 atgattggga tgattgtaag cttagttgtg gtactaacgg tcgctaatat atcaatgaac
    36721 aaaaagaaac gctatgcaat ggcagcaaac gtaccagctg aaggtggcga cgcaccaatg
    36781 atctcatggt tagccgtatt attaccagtt ttaggggtcg ttcttttaga tcttccaatc
    36841 atcttaggtt ttattctagc aggtatctgg gcattgctgt ttactggaaa attgcgcgga
    36901 ggttataaag aaatctgtcg tcagtttgcg aaattattta cagatggcgc agtagatgtt
    36961 gcgccaatgg ttggtttctt gatgacctta gcgatgttca ataattcagc tgcgtatgct
    37021 tctccttatt tttcagctat ttttggagat tggataccgc aatcaccatt agtcttggca
    37081 atcgtatttg ctatattgac accactagga tttttccgcg gtccaatgaa tctagtcggt
    37141 tcaggctcag ctattttagc tgtcgtatta gctgttaatc caacgatgtc gccagccttt
    37201 ttgttcccgt tatttgcaat cacaacgatt gctcctcagc atttagatat tacacaatct
    37261 tgggttgctt ggggattagg ttatacaaaa gtaacttctc gagaatatat gaagaaatcc
    37321 atcccaactg gttggatcat cggagcgatc ttatgcctga tcacgttctt attgtacggg
    37381 aacgcctagt aaacaaaacg tcgataaaaa cgattagatg aatggaggaa aagaaaatga
    37441 aacgttttgt gcgaatggga attgatgttg gcggtacaca tacgaaagca gtcgcaatcg
    37501 ataatgcgac gcacgaaatc atcggaaaat cttcagtgaa aacaacccac gatgatgtcc
    37561 gtggagtagc cgcaggtgtc gttcagtctt ttcaaaattg tttgctggaa aataatatca
    37621 gtccagaaga tgttgtgttt gttgcacatt ctaccacaca agcgactaat gcactgattg
    37681 aaggagacgt agcaaaagtc ggcgtaatcg ggatggcaaa aggtggatta gaaggttttt
    37741 tagcaaaacg acaaactaga ttgaacgata tcgatttagg gaataagaaa aaaatagaga
    37801 ttgtcaatgc attcttacct gtcaaacact taaatgtaga ccgtgtttca gaaacgattt
    37861 cttctttaga aagagaaaga gcggaggtct tggtttcttc tatggcattt ggagtagata
    37921 atggggaacc agaacgagtt gtttatgaag cagcatcggt aaaatcgatc cctacaacga
    37981 tggcttctga catcacaaaa ttatatggat tgacaagaag aactcggaca gcagcaatca
    38041 atgcatctat tttaccaaaa atgctagata cggcaacctc tacagaagat tccgtacgag
    38101 aagcaggggt caatgtttct ttgatgatta tgcgcggaga cggcggagta atggaaatca
    38161 atgaaatgaa aaaacgacct gttttaacca tgctttccgg tccagcagca tcagtcatgg
    38221 gctctttgat gtacttgaga gcgtctaatg gtgtttattt tgaagtaggc ggaacaacaa
    38281 ccaatatcgg ggtcattaaa aatggacgtc cagcaatcga ttattcaatt gtaggtggcc
    38341 acccaacata tatctcttca ttagatgttc gggttctagg tgtggcaggc ggttcgatgg
    38401 tacgggctaa tcagtcagga atcatcgatg tcggtccacg ttctgcacat attgccggtc
    38461 tagattatgc agtatttacg gagacagaaa aaatcaaagg tcctaaggtt gaatttttct
    38521 ctcctaaaga aggagaccct gctgattacg tcaaggtagt gatggaagac ggagaagaag
    38581 tgactattac aaatacatgt gcagccaatg tccttggatt agtgcaagaa gaacattttt
    38641 cttatggaaa tgtcccatct gcacgaaaag ccatccaagc attagctgat tattgtcata
    38701 cgacggttga agacatcgca gaacagatca tggaaaaatc ctatgctaag attgaaccgg
    38761 tgattttaga attggcagac aagtatcact tggagaaaga tcagatttct cttgtaggtg
    38821 tagggggcgg cgctgcctca ttgattactt actttagtaa taaaatgggt gtgaaatatt
    38881 cgattcctga aaacgccgaa gtgatttctt ctattggtgt agcacttgca atggtccgag
    38941 atgttgtaga acgtatcatc ccttcgccaa gtaaagaaga tatacgatcg ttgaaaaatg
    39001 aagcgatgaa taaagcgatt gaatcaggcg ctacaccaga atcgatcgaa gtccacgtag
    39061 aaatcgatcc acagacttca aaagtaacgg ctatcgctac tggttctacg gaagtgaaag
    39121 caaccgatct aaccaaggag atcacaacag aagaagcact agagcttgct gcagaggata
    39181 tgcgattaaa taaaaatgaa gtttgcttat tggaaaatac acctttcttt tatgtatgcg
    39241 gcgaacagaa tcgttcaaaa aatgctggaa gtcttcggat catcgatcaa aaaggattta
    39301 tcaaggtcca acgtggacat gcttcatgta tgaaaacaac tgcagccaat tatatgacag
    39361 ctgtcgaaca actttgggaa gatatggcag tttatcaaac tgaattgatt gcccgaccag
    39421 aattttatct ctgcttagga gcaagagtct ctgattttac agcgacggat ctggaacaac
    39481 tacagctttt gatggatctg gaagtatcta ctatggaacc ggaggaagaa gtgatcgtcg
    39541 ttgccggaaa tatcaaacaa acataagtta gaagagttac taaacgaatt acaacagatc
    39601 cccgaagaaa tttggggatt ctaccagttt cggcgagatt tattttggaa aaagattcct
    39661 ttgtccaagc agaaaattct tatacaacaa tcaatcgatt gtggtatcga aacggcatgt
    39721 agcatcaaaa aaaagtaccc ttttgccgat gtaggagaaa tttgtgaaca aatggctgtt
    39781 ccaatcgttt cctgtgaatc agagcaaata aacgaacgaa tcacttttgc aacttatgca
    39841 gaagatgaag ggattcgatt gatgacggag ccgttagaaa aattaaaatg ttcaggacta
    39901 gcttcgatct ctaaagaaac agcgcaagct ttgattattg gacatgaact atttcaccac
    39961 atcgaagctt ctgttaaggg aatttatacg caaagcgaaa aaattgtgct gtggcggttg
    40021 cctttttata cacatcaatc aaacattcgt gcattgagcg agatagcagc gatgagtttt
    40081 tcaaaagaga tgaatcaaag cgatttttcg ccttatgtat tagaggcagt cttactttgg
    40141 ccatataatg aaattcgtag ccaagggatc ttagaagaaa taaaaaaaat agaaaaaaga
    40201 tgtacggagt atgatttaga ttacaaataa agagactgtg acaaaagtcg tgtcacagtc
    40261 ctttttttcc gaataaacgg tgttctcctg tcaactcctc ggtcacaagt caaaatattc
    40321 aacaaacatg agaagctgtt ttttgaaatt gttccttgtg actcggagat gaacggcagg
    40381 ctcacgacct cttggaaaac ggtgttcaaa agcttgcatc tgcggtaata agtccagcca
    40441 agttaaaaac ataagaagct atttttactt ggctgttctt attacttgat gcagggcagc
    40501 tttttcacaa cctctcaata aacggtgtgc aatcagctga ccctcggtat tagctcaaaa
    40561 aaaacggcaa aatatgagga actattttgc cgtttctttc tctaatactc aggtcaaaac
    40621 gctgattcca aaacctctta tttgatgggt ctgtcctgaa tatcttcaaa ataatcgggg
    40681 taattatgaa tcacgtattc ttgctcctcg ataatcatat gtaaatgcat cgtgcaaaga
    40741 aatccgactt catcaaagtt atgatcaatc attgattgaa gcattgtctg atgttcatct
    40801 aatactcgac cccagtctaa ttctgaaatc gtcaaacgta accatctgaa acggttcaag
    40861 tgcgtactat aactttctag ccaatcccaa atttctcgtt ttccagcaat ttcataacaa
    40921 gttcggtgaa aatcagtatc caaatcaaaa aaagcttttt tattttgagc gattactgcc
    40981 tgatcggttt gttctagtat tttttctagt ttaacttgat cttgcttggt cattttcgca
    41041 ctgcattctt gcaggatcgg tttttccaac ttttcccgcg tataacgggc taatgaagca
    41101 gatcggatat cgatttttga aacataagtg ccggactgtg gaatggtttt tacaagctct
    41161 tgattgcgca gttggatcag tgcttctcga atcggtgtac gcccgatagc tagttgttct
    41221 tctaacactt tatcggagat tttacttcca ggtgctaact cggaataaat gatttgttta
    41281 cgtatagatt cataagcttg ctgttgcaaa ttattgataa ccatttaacc ttcctttcta
    41341 tgcagatata atctattata acataaatcg cttacaaatc gtgtgggcat aaaaacacag
    41401 tctgcaaaaa aagccctgat aggcatgcct attagagcct cgaaaagaaa aatattgaat
    41461 caatctggtc gtacctcttg gatcggtttg acacgaccgc cgattctttt agcaaaagct
    41521 tcggattctt ttttgtcttt gaaaatgagc agattgtcta agtttttttc ccgagtgcga
    41581 cagccagttt tatcgatgta accgtgcatt actttaacga catacatggg gatcacctgc
    41641 ttttttcttt tcattatacg aactactcga cacaatacaa gaaaaatgct tagacggtct
    41701 ttattaagaa tttacatcat ccaaagaagc gtacgcttgg aataactgat ctaactccgg
    41761 attgactttg ctcagcttca ctaatcgttg cgaatcagaa agtaaaaaac agtgtttact
    41821 actgccagta gtttttaatt ttttgtcttc agttcccaca atttcgtagc taaaatccaa
    41881 ccgtgtcccc gtatactttt ggatagttgg atggatgctc actttttctc cgtaatggat
    41941 catttcttta tagctgcaat ttacttccag aacggggatg atgatcccag attcttcgat
    42001 ttttttatag ggaaacccta gatgtaccaa taaggctacc cgagcctctt caaaccagcg
    42061 gatataattg ctgtgatgaa taatccccat ttgatctgtt tcataataaa aaggttctcg
    42121 cacataacct gtaaatttct ccatgactca tgcctcgttt tccattgatt ttttacaaaa
    42181 ataattcatc catttcggaa gtgcttcgct gatttgtgtc ggcaaaacaa tatattgttc
    42241 ttttgccagc tggtctccaa tgaaactatg aagataaata gctgctgcaa tcgtttggtc
    42301 attttgagga aactgggcta aaaatcctgt gatcatccca gctaaagtgt cacccatgcc
    42361 gcccgttgcc atagcagcag aacctaaagg attggtgtag aagtgctggt gaccataaat
    42421 ttttgtctca tgacttttca aaacgagcac agcaccgatt tcctgttgct tctttttgtt
    42481 ttctttatcc cgttgttctt gtatcggtag agaactcaac cgttgccact ccatttgatg
    42541 aggtgtaagt acagtttgtt cgggataggg tagcaaaaga tgattagcag caagtaaact
    42601 taaagcagag ccatcaatca ccagccattg ttcttttgat tggttttcta gtacttgttt
    42661 gaaacgttcc aaactcttag aagaagtacc caatccggga ccaatcaaga gtacatctgc
    42721 ttgctttatt acggaaagaa actggtcagt atccgtccaa actacaatca ttgcttctgg
    42781 cagatgactg tgaagagcac tccgattttt ttcatcagtt actacagtcg tgagacccgc
    42841 tccgctgtgt acggcagcta aagcactcat aatgattgct ccgccatatt gttcattgcc
    42901 gccaatcaaa acgatacgtc caaatgttcc tttatgtgaa atttttggac gaggtgtgat
    42961 gactcttttc actagttgtt cgtttatcag catctaaaaa cctcctttta ctcattatag
    43021 cgtatatttt ttttagagaa aaacagataa gaaaaggaat tgtcagattt tttgaactat
    43081 ttttttctgt aatttgtggt atcatgaaca cgaagactta aataagtgga ggattaactt
    43141 tatgacaatt gattggcaaa aagaagtaga agcacgtaaa gaagacttgc ttgaagactt
    43201 gaaaaatctt ttacgtgtca acagcgagcg cgatgactca aaagtaacac cagatgcacc
    43261 atttggacct ggacctcgcg acgcattgaa acatatgtta gcttatggcg aacgtgatgg
    43321 atttaaagta aaaaatgtcg ataactatgc agggcatatt gatcttggcg aaggagacga
    43381 aacgctaggg atatttggac acatggatgt cgttcctgca ggagatggct gggacacaga
    43441 tccttatgaa ccagtaatca aggatggaaa gatctttgca cgcggatcaa gcgatgacaa
    43501 aggtccaagt atggcagctt actatgcgat gaagatcatt aaagaacttg acttgaaact
    43561 atcaaaaaaa gttcgcttcg tagtcggcag cgatgaagaa agcggctggg gcgatatggc
    43621 ttattatttc gaacatgaag aagaaccaga ttttggtttc tcaccagatg ctgaattccc
    43681 aatcatcaat ggtgaaaaag gaaatgtttc tttagcttta cgcttcaaag gcgacaatgc
    43741 aggagattat gtcttgaaat cttttgtttc cggacttcgc gaaaatatgg tgccaggaac
    43801 agcaactgca gcacttcaag taccaagtgc agatgcagct atcgcgatgg aagaagcatt
    43861 ttaccaattc atcgaagcaa atccagtaag cggaacgatt gaagcggaca atacgtatgt
    43921 aaaaatcgaa ttagttggta aaggcgcaca tggtgcaagc ccacaatctg gtatcaatgc
    43981 aggttctttc ttggcattgt tcttagataa ctatgaattc ctaggatctg ctaaacaatt
    44041 tatccatgta gcagctgctt atgtccatga agatttttat ggagaaaaac taggagtcgc
    44101 ttatgaagat gaaaaaatgg gcaaattgac aatgaatgct ggactatttg cttttgaaga
    44161 aaatggtaca gaggaagcga acttcatcaa tatgaatttc cgttttccaa aaggtgtaac
    44221 agtagacgga ttgcaaagtg acatcgaaca aacagtgggg caagaaggcg caacagttac
    44281 tcgaggtgct cgcgtaatgg aaccacatta cgtaccaatg gatgatccat tggtggctac
    44341 attattgcaa gtctatgaag accacactgg agaaaaaggc tacgaacaaa tcatcggtgg
    44401 cggaacttac ggacgtttgt tgaaacgtgg cgttgcttat ggagcgatgt tcccaggata
    44461 tactgataca atgcatcaag caaacgaatt tatgagtctt gatgacttgt tcagagcaac
    44521 agcaatctat gcagatgcca tctatcgttt ggcgaaataa ttaattaaaa agaggatcaa
    44581 gaattgcaaa ttatttttgc agtcttgatc ctttttttac tttctactgt ggtattcatg
    44641 ataaacatga tatagattca attcatattc tttcttagcg ttcgtgacga ctgtatccaa
    44701 aatcaaccct gttactaatg aaagaagtgc taaagtcatc aatccagtac ttaaaatcgc
    44761 agaagggatg cgtgtaataa agcttgtcag catatattcg cgaatcacag gaatccccgt
    44821 gaccaatcca aataaaaaga agaagatggt ccaaatccca aagaaaagca aaggcttata
    44881 atctttaaac attttaataa tcatcatgat cactttgaat ccgtcagaga atgtattcaa
    44941 ttttgattcg ctgccttcag gacgatcacg ataatcgatt gggatttcaa cgaacttgaa
    45001 ttttttatct aaagcatgga tcgtcaattc cgtttcgatt tgaaaaccag aactcataat
    45061 aggaaaactt ttgacaaaga tacgattgaa tcctcgatag ccggtcatga catcaagaat
    45121 ttttgtttta tacattctag taattgtatt tctaacaagg ttatttccaa aatcgtggaa
    45181 aggtctctta ttctcatcaa agtaggttcc atttgatagg cgatcaccaa tgaccatatc
    45241 tgcttcacca gaacgtaatt tctcgagcaa accatgtaca gcttctgcag gataagtatc
    45301 atcgccatct accattaaat aatagtcggc atcgatatca aagaacattt ggcggatcac
    45361 atttcctttt ccttgacgag gttctttttt tacgattgct ccaccttgaa cggccaattc
    45421 gtatgttcga tcggtcgaat tattatcata gacataaata tctgcttctg gtaattctcg
    45481 tttaaagtct gcaatgactg ttgaaattgt tgcttcctca ttgtaacaag gaatcagaac
    45541 agcaattttt tcttgttgtt ccatttttca ctctccttaa ctatagaaaa caaaagctaa
    45601 attaaaaata cctcataatc aaaggaaatg ctagtttttc ccgctaaata tcatttattt
    45661 aaaaagaaaa tactggaata tatgtttgga aagctctatc taaaaaacca cccactacaa
    45721 aagaaggaca tgatacctct cttttgaata gtgggtgcgt attcgttctc tcactttttt
    45781 gacgtattaa tctgttgcac ctttttttct tgaaatttct aatacggttc ctgtatgagc
    45841 atctgctaaa aattcataat aaacagtttc gccatcttct attcgagaaa gacctccccg
    45901 ataagcactc gaccgaacgg cgaatttcct aataggttcc ttttcaaaag agatccaaga
    45961 accttcgatt gcaccttctt ttagaaaaga tgacttgata ttttcaagta cttggtctgc
    46021 tgacaatact tttttgcgat gataccaaat cgttgaagct accccgctca ataatcctag
    46081 accgattcca actgctaacc cgcctttaaa atagcttagt tcgctttctt catacatgtg
    46141 gacatacctc cttcttctca cttgttactc cttgtgctta ttttaccaca ctctcatatt
    46201 ttctttgaaa taaataaccg ctaccagaaa aaataagcta taataaatac gatcggtctg
    46261 cagaaaaaat catattttat ccgcagatca atataagtct gagaggagtt tagtctgaaa
    46321 tttagacgaa tagcatatgg aagaaaaaac atttcaacga atcaaagagt taacagaatt
    46381 acaaggaaca agcggttttg aacaagatgt tcgcgcttat atggaaagtc atatggaacc
    46441 gctggtagat gagttacagt tagatggttt gggcggcatt tttggtctgc gccatcatga
    46501 agaagcggat gcaccccgtg taatggtcgc agcacatatg gatgaagtcg gattcatgct
    46561 gacacaaatc caagaaaacg ggctttttaa agtcgtacct ctaggcggct ggaatcctta
    46621 cgttgtttct gctcagcgtt ttacacttaa aacctctact ggtaagaatt atccatgtat
    46681 ttcttcttcc gttcccccac atttattgcg aggaacaagc ggacaaaaat cagtagaagt
    46741 aaccgatatt ttgttcgatg ctgggtttga atcaagagaa gaggcaatga gttacggtgt
    46801 ccttccagga gacacaatcg ttccttacgc tgaaacgatc aaaacagcca acggaaagaa
    46861 tattatcagt aaatcatggg acaaccgcta tggctgtaca atggtattag aagctttaga
    46921 agcgttgcaa aatgaaacat taggtcatac attgattgca ggcgcgaatg tccaggaaga
    46981 agtaggcttg cgtggttcta aagcttctgt caataaattc aagccagatc tgttctttgc
    47041 agtagactgc tctgcagcag atgatacagt gacgaaaaat ggcacattcg gacatttagg
    47101 agaaggtaca ttgatgcgta tccaagatcc aggtttgatc atgcttcctc gtttgcgcga
    47161 gtacttgctg gatatcgctg aaacaaacaa tatcccttat caatactttg tttcaaaagg
    47221 cggtacagat gcaggtgctg ctcatacaca aaacgaagga atcccaagta cagtgattgg
    47281 cgtagtggga cgttatatcc atacgcatca aacgatgttc agtattcgcg attttgaagc
    47341 tgcacgagaa atgttgattc aaacactgaa aggtttggat aaatcaacag taaatacgat
    47401 cgtatacgga aaataatgcg atagtgaaac tataaaatct ggcaaaagat tgctttttgc
    47461 cagatttttt ttataaaaag aggatcaatg tttgttagtt cgaaagaaag gtgtataatt
    47521 taattgaaaa atacataaac agaaagtaga ggacaaagaa tgattatccc aaatagttta
    47581 gaagaattag caggctacgt agaaactgga aagagtgtat ttttctttac tgccggctgg
    47641 tgcggagact gccgttttat caaaccgcaa atgcctgaaa ttgaaaatga cttttctgat
    47701 tggcaattta ttgaagtaga ccgtgacaag tacatagatg tagccgctga atggaacatt
    47761 tttggtatcc caagttttgt cgtgatccaa gacggaaaag aattaggtcg tctagtgaat
    47821 aaagatcgta aaacaaaaca ggaaatcgaa tcgttcctag aaagtgtaac aaaaggctga
    47881 catctgttag gaggggtcaa gatgaatcaa gaatataaga atattttagt aggtatcgac
    47941 ggtagtgaac aagcacttgc tgctttcaaa aaagcggtag aagtggctcg ccgtaataat
    48001 gggaaagtat atgtagcaaa cgtaatcgat cagcaatttt ataactttat gggctatgca
    48061 cctattgatc aaaatctagt cgatcagcaa actgaaacag ccaaggaaat gatcgaagaa
    48121 tgtaaagaat atgggaaatc tgttgattac acaaatatag aaggaattat tgcatatggt
    48181 tctgttcgtg aatccatggc agtcaaattg ccaaaaaaat atgagatcga tctaatcatg
    48241 gttgggcagt caggtctaaa tgcagtcgaa cgctttatga caggaagtgt agccagctac
    48301 gtgatacgtc attcaccttg tgatgtcttg atcgtttctg acgaagaaga acagccaagt
    48361 aattaagcaa gtggaacttg tacgaccttt ttaatcaatt aactaaaaca gtaaagggac
    48421 tgtgacaaaa gtcttgtcac agtcccttgt tacgaataaa tggtgttcca gaagaggctt
    48481 cttcggaaat aaagcatgaa aaaaatttca tgcagtgaat gcaatttttt gttaagataa
    48541 atctcagcaa aggataatgg aggaaagaac atgatttttg cttataacaa agcacacgtc
    48601 ggagacacct tgatggttat tatagccgac gataaaggaa cagaaaacac tgttgaacgc
    48661 aaatggaatg ttgctcggat caaagatgaa caaggtcaag ttgttgcttg gaactttttc
    48721 catatctccg atcatctaac aatcgaaggg aacggccaag taagcttaac agatgaggaa
    48781 ttagcgaaat tgaatcgatt gatcaaagaa gcaggattcg aagaacagct tgaagctgat
    48841 catgaaccga agatcgttgt cgggtacgta aaaacatgcg tcccacatcc tgattctgac
    48901 catttatcga ttactgagac agaagtagac aatggtacag tattgcaaat cgtttgcggt
    48961 gcacccaata tcgaagctgg acaaaaagtt gtcgttgcaa aaccaggagc tatgatgcca
    49021 gatggaatga tgatctggcc aggaactttg cgaggggtag atagctatgg aatgatctgt
    49081 tccgctcgtg aattgcattt gccaaatgct ccagcaaaaa aaggaatctt agtattgcct
    49141 gaggatgccg tagtcggaga agcatttcca aaataaagag gttgtgacaa gtctttgtca
    49201 caacctcttt tttattaatt ttcactattt tgattttgtt ttaatgccga ttgatcgatc
    49261 gtcaattcaa cagtagttgt tttttctttc gagccttcat agtaagtgat tttgacagaa
    49321 tctcccactt ttttcttata caaagcagat tgaagttcta caccagaaga aacttctttg
    49381 tcatcgatct tagtaatgac gtcgtattgt ttcaatccag ctttttcagc cggtgtagct
    49441 gtttggacat ttgtcacgat gacaccgtta gttacagatg aaggaatctt caagatttgt
    49501 tcttgttgct gagtagaaac ggcagataag tcgaccattg tgatacctag agctggacgt
    49561 gtcacttttc cgtctttttc cagttgattg atgatattca ctacatcgtt acttggaata
    49621 gcaaatccca ttccttctac gcttacatta gaagtagatt cagaagtact tgcgatctta
    49681 cttgagttga taccgataac ttgtccttcg atattaacta aaggaccacc agaatttcca
    49741 gggttgattg ctgcatctgt ttggatcgca ttgatattga ctgtttcgtt cgattcattc
    49801 gtacttgtca cttgtcggtt caaggaagaa atgattcctg aagtgacaga atttgcatat
    49861 tcagatccta gtggggaacc aatcgcaatc gcaggctcac caaccttcag agcacttgag
    49921 tcaccaaaag aggcaactgt ttcgactttg tctgaattga tcttcaacac cgctaaatct
    49981 gaataagcat ctgttccaac taattcagct tttaccttcg taccgtcttt catcaagact
    50041 tcaagacctt gctggccatc tactacgtga ttattcgtga ctacataagc agtattcccg
    50101 tcttttttgt agatcacgcc gcttccttca ctataagctt ccaaattact atcatctgag
    50161 ctgctacttt cttcttgctg cccgaatagt ccgccaaaac cgcttgattg gttttgactt
    50221 tgtaagttga taacagaaac gacagcgtct tgaactttat ctaccgcttt ggtgatatca
    50281 gaatctacat tgactttgac attttccaca actgtttcac cggcagaatt ctgattgccg
    50341 cttgtagcag tagaactatt gttgccagtg cccatcgctg cataaaaaat gccagctgtc
    50401 agtagtcctc caacgatccc tccaacaagc cccagaccca acttacgcca gaggctatta
    50461 tttttatttt ttttcatctt tggtgtcaca ttttttctat ccatgtgttc ctcctccaat
    50521 tacattcatt tatctactgt tagtatagtc ttatttgttg actttagtct actttgagac
    50581 tttgaacttt ttatgaaaaa ctttaggaaa aatcattgtt ttcagatgaa aatatttgat
    50641 tttctttttc cacagatatt gtgtaaaact acgcggatag gattggaaaa ataagggata
    50701 aaacatatcc acagcctgtg tataaagtgg ataaattctt ataaaacgta tgtttgccta
    50761 atgaatgtga tgaaataagg taaaacaacg ctgttttctg tggataaacc tgtggatgtt
    50821 gtgcataact gttggggaaa tctttttaac aaaaatagtc aaaataaaca tatagacgaa
    50881 aaaattgatt ataataaaca aagtgagcgt gaagatcaaa ggagagaaaa catgaatatc
    50941 aaaattattt cagtaggaaa attaaaagaa aaatacttga tccaaggtat caatgagtat
    51001 gtcaaacggc tgaatgccta tgcgaaaatc gaattgatcg aagttcctga cgaaaaagcc
    51061 ccggagaatt taagcgaagc gcaaatgaga caagtaaaag aaaaagaagg agaacggatc
    51121 ttagcgaaaa tcaaagaaca agaatacgtc tatggcttag caattgaagg gaaaaatccc
    51181 acaagcgaat cttttgctaa acaaatcgac caattaggta tccaaggaaa aagccacctt
    51241 gtttttgtta tcggcggttc tttaggactc agcgaagccg tcatgaaaag aagcaatgct
    51301 cagatctctt ttggcaaaat gacgtatcca catcaattga tgcgcctgat cctcgtcgag
    51361 caaatctacc gtgccttccg gatcaacgcg ggggctccat accacaaata atgatatttt
    51421 ttaagagaaa aatagcataa aaatctagtt atccgcataa aaactggact tatcacactt
    51481 tatcaaggtc aaaaccactc aatttactac taatttacta cttatgaatg agctttgata
    51541 cgacgattta tccttgaaaa gtgaagatat aaagatactt ccaataaaat ttgaatattt
    51601 aataggtaga cacttcaaaa aatgaggtgt ctattttttt acccgatttt gaaaggaagt
    51661 gaacttatga aaacaaaaaa tcaagaatca aaaggtcgtt ccccactctt taagaccatc
    51721 aaacattcat tcagccaata aaaaagaaag gataggtaaa aatatggaac ttaaatttgt
    51781 gattcccaac atggaaaaaa cattcggcaa tttagaattt gctggcgagg ataaagtcgt
    51841 tcagcgaaga atcaacggac ggctaactgt cttatcaaga agctataatc tctattctga
    51901 tgttcaaaga gcagatgata ttgtggtggt gcttcctgct gaagctggcg aaaaacattt
    51961 cggctttgag gaacgtgtga agttagtcaa tccacgtatt accgcagagg gctacaaaat
    52021 cggcactcgt ggttttacaa attacctttt acatgctgac gacatgataa aagaataaag
    52081 aaagagagga aaaatgatga gattagcaaa tggcattgta ttagataaag acacgacttt
    52141 tggagaattg aaattctctg ctctacgtcg tgaagtgaga atccaaaatg aagacgggtc
    52201 ggtttcagat gaaatcaagg aacgtaccta tgacttaaaa tccaaaggac aaggacgcat
    52261 gattcaagta agtattcctg ccagcgtgcc tttgaaagag tttgattata acgcacgggt
    52321 ggaacttatc aatcccattg cggacaccgt tgctactgcc acctatcaag gagcagatgt
    52381 tgactggtat atcaaggcag acgatattgt gctgacaaag gattctagtt cattcaaagc
    52441 tcaaccacaa gcaaagaaag aaccgacaca agacaaatag tcgctaggta gaaaggagac
    52501 tttttcgcat gaaacagcgt ggtaaaagga ttcgcccatc tggtaaagat ttagtctttc
    52561 attttacgat agcgtcactc ctgcctgttt tcctgctggt tgtcggactg tttcatgtga
    52621 agacaatcca gcagatcaac tggcaggatt ttaacctatc acaagcagat aagattgaca
    52681 ttccctattt aattatcagt ttcagtgtcg caattcttat ctgcttgctg gtagcgtttg
    52741 tattcaaacg ggttcgctat gatacggtta aacaacttta ccaccgtcaa aaactggcaa
    52801 agatgatact tgaaaacaag tggtatgaat ctgaacaggt caaaacagag ggtttcttta
    52861 aagatagtgc tggtcgtaca aaggaaaaga taacctactt ccctaaaatg tattatcgac
    52921 ttaaaaatgg cttgatacag atacgggtgg aaatcacgct gggaaaatat caagaccaac
    52981 tcttacactt ggaaaagaaa ttagagagtg gcttgtactg tgagctgacg gataaagagt
    53041 taaaggattc ctatgtggaa tatactttgc tctatgacac catagccagt cgtatttcta
    53101 ttgatgaagt agaagctaaa gatggtaaac ttcgcttaat gaaaaacgta tggtgggaat
    53161 atgataagct ccctcatatg ttgattgctg gtggtacagg tggcggtaaa acttacttta
    53221 tactgacact gattgaagcc ttgcttcata cagattcaaa actgtatatt cttgacccga
    53281 aaaatgctga tcttgcggac ttaggttctg tgatggcaaa tgtctactat agaaaagaag
    53341 acttgctttc ttgcattgaa acattctatg aagaaatgat gaaacgtagt gaggaaatga
    53401 agcagatgaa gaactataag actggcaaaa attatgctta cttaggtctc ccggcacact
    53461 tcttaatctt tgatgaatac gtcgctttca tggaaatgct gggaacaaaa gaaaacaccg
    53521 cagttatgaa taagctgaaa cagattgtca tgttaggtcg tcaagctggc ttctttctaa
    53581 tactggcttg tcaacgtcca gacgcaaaat atttaggcga cggaatccgt gatcagttta
    53641 atttcagagt ggctttaggt cgtatgtctg aaatgggcta tggcatgatg tttggcagtg
    53701 acgtacaaaa ggatttcttc ttaaagcgaa tcaaaggtcg tggctatgtt gatgtaggaa
    53761 caagtgtcat atcagagttt tatactcccc ttgtaccaaa aggatatgat ttcttggagg
    53821 aaattaaaaa gttatccaac agcagacagt ccacgcaggc gacgtgcgaa gcggaagtcg
    53881 caggtgtgga ctgatcttgc tggctggtgt ggcaatagcc acgccagcac ttaacccctc
    53941 ggtatctaac aggggggtac aaatcgacag gaaacagtca aaaaaacatt agaaaatcct
    54001 ttggttacaa gggatttaca aaatttcagc gtatgtcaaa tgggctttaa aagttgacat
    54061 acgccttttt gattggaggg atttttactg aatgaacaaa cttggttaca gcatttaaaa
    54121 gaaaaacgct tggcttatgg actatctcaa aaccgtttag ctgttgcgac tggtattaca
    54181 aggcagtatc taagcgatat tgaaacagga aaagtcaagc catcagagga tttacagcag
    54241 tccctttggg aagctctgga acgcttcaat cccgacgctc cccttgaaat gctgtttgat
    54301 tatgtaagaa ttcgctttcc gacaacagac gtacagcagg tggtcgaaaa catcttacaa
    54361 ctgaaactgt cctattttct tcatgaggac tatggtttct attcttattc agagcattat
    54421 gctttaggcg acatattcgt cctttgctcc catgaactgg acaaaggagt tctggtggaa
    54481 ttgaaaggtc gtgggtgcag acaatttgaa agctatcttc tggcacaaca aagaagctgg
    54541 tatgagttct ttatggacgt tttggtggct ggcggtgtga tgaaacgcct tgaccttgcc
    54601 attaacgata agacagggat tttaaatatc cctgtactca ctgaaaagtg ccaacaggaa
    54661 gaatgtatct ccgtcttccg cagttttaaa agctatcgca gtggcgaact ggtacgcaaa
    54721 gaggaaaagg aatgtatggg aaacaccctc tatatcggtt cattacaaag tgaagtttat
    54781 ttctgtatct atgaaaagga ctacgagcag tacaagaaaa atgatattcc cattgaagac
    54841 gcagaagtaa aaaaccgttt tgagattcga ttgaaaaatg agcgtgccta ttatgcagtc
    54901 cgtgatttac tcgtctatga caatccagag cataccgcct ttaaaattat caatcggtat
    54961 atccgttttg tagataaaga cgattccaaa cctcgttctg attggaaact gaatgaagaa
    55021 tgggcttggt ttattgggaa caatcgtgaa cgattaaaac taaccacaaa accagagcct
    55081 tactccttcc aaaggacgct gaactggcta tctcatcaag ttgccccgac cttaaaggtt
    55141 gcgattaaac ttgatgaaat caaccagacg caggttgtaa aagacattct cgaccatgcg
    55201 aaactgacag accgacacaa gcagattttg aagcaacagt cagtaaaaga acaggacgtg
    55261 ataacaacaa aaaaataact caaatacaaa ttcattgaat atagagagga gaacattttt
    55321 atgaattttg gacaaaacct
//
LOCUS       DAFKHN010000008        54183 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFKHN010000008 DAFKHN010000000
VERSION     DAFKHN010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 54183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.008"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            399..3206
                     /locus_tag="LY912_000488"
     CDS             399..3206
                     /locus_tag="LY912_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBM6954208.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3397..3888
                     /locus_tag="LY912_000489"
     CDS             3397..3888
                     /locus_tag="LY912_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6954209.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3991..4980
                     /gene="manX"
                     /locus_tag="LY912_000490"
     CDS             3991..4980
                     /gene="manX"
                     /locus_tag="LY912_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBM6954210.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            5013..5816
                     /locus_tag="LY912_000491"
     CDS             5013..5816
                     /locus_tag="LY912_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBM6954211.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5837..6751
                     /locus_tag="LY912_000492"
     CDS             5837..6751
                     /locus_tag="LY912_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBM6954212.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6834..7208
                     /locus_tag="LY912_000493"
     CDS             6834..7208
                     /locus_tag="LY912_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBM6954213.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7347..7592
                     /locus_tag="LY912_000494"
     CDS             7347..7592
                     /locus_tag="LY912_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBM6954214.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7764..8828
                     /locus_tag="LY912_000495"
     CDS             7764..8828
                     /locus_tag="LY912_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBM6954215.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9074..9499
                     /locus_tag="LY912_000496"
     CDS             9074..9499
                     /locus_tag="LY912_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBM6954216.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9492..9941
                     /gene="nusB"
                     /locus_tag="LY912_000497"
     CDS             9492..9941
                     /gene="nusB"
                     /locus_tag="LY912_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBM6954217.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10038..10892
                     /locus_tag="LY912_000498"
     CDS             10038..10892
                     /locus_tag="LY912_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBM6954218.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10893..12230
                     /locus_tag="LY912_000499"
     CDS             10893..12230
                     /locus_tag="LY912_000499"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBM6954219.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12235..12459
                     /locus_tag="LY912_000500"
     CDS             12235..12459
                     /locus_tag="LY912_000500"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBM6954220.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12461..13351
                     /locus_tag="LY912_000501"
     CDS             12461..13351
                     /locus_tag="LY912_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBM6954221.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13360..14178
                     /locus_tag="LY912_000502"
     CDS             13360..14178
                     /locus_tag="LY912_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBM6954222.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14285..14734
                     /locus_tag="LY912_000503"
     CDS             14285..14734
                     /locus_tag="LY912_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBM6954223.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14752..16434
                     /gene="recN"
                     /locus_tag="LY912_000504"
     CDS             14752..16434
                     /gene="recN"
                     /locus_tag="LY912_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBM6954224.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(16489..16605)
                     /locus_tag="LY912_000505"
     CDS             complement(16489..16605)
                     /locus_tag="LY912_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBM6954225.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(16678..17634)
                     /locus_tag="LY912_000506"
     CDS             complement(16678..17634)
                     /locus_tag="LY912_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBM6954226.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            17805..18173
                     /locus_tag="LY912_000507"
     CDS             17805..18173
                     /locus_tag="LY912_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBM6954227.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18343..18774
                     /gene="mraZ"
                     /locus_tag="LY912_000508"
     CDS             18343..18774
                     /gene="mraZ"
                     /locus_tag="LY912_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBM6954228.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            18795..19754
                     /gene="rsmH"
                     /locus_tag="LY912_000509"
     CDS             18795..19754
                     /gene="rsmH"
                     /locus_tag="LY912_000509"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBM6954229.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            19759..20160
                     /gene="ftsL"
                     /locus_tag="LY912_000510"
     CDS             19759..20160
                     /gene="ftsL"
                     /locus_tag="LY912_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBM6954230.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            20161..22353
                     /locus_tag="LY912_000511"
     CDS             20161..22353
                     /locus_tag="LY912_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBM6954231.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGIAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            22379..23341
                     /locus_tag="LY912_000512"
     CDS             22379..23341
                     /locus_tag="LY912_000512"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBM6954232.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            23355..24716
                     /locus_tag="LY912_000513"
     CDS             23355..24716
                     /locus_tag="LY912_000513"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBM6954233.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            24742..25830
                     /gene="murG"
                     /locus_tag="LY912_000514"
     CDS             24742..25830
                     /gene="murG"
                     /locus_tag="LY912_000514"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBM6954234.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            25845..27065
                     /locus_tag="LY912_000515"
     CDS             25845..27065
                     /locus_tag="LY912_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBM6954235.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            27221..28546
                     /gene="ftsA"
                     /locus_tag="LY912_000516"
     CDS             27221..28546
                     /gene="ftsA"
                     /locus_tag="LY912_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBM6954236.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            28569..29810
                     /gene="ftsZ"
                     /locus_tag="LY912_000517"
     CDS             28569..29810
                     /gene="ftsZ"
                     /locus_tag="LY912_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBM6954237.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            29827..30504
                     /locus_tag="LY912_000518"
     CDS             29827..30504
                     /locus_tag="LY912_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBM6954238.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            30518..31117
                     /locus_tag="LY912_000519"
     CDS             30518..31117
                     /locus_tag="LY912_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBM6954239.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            31132..31419
                     /locus_tag="LY912_000520"
     CDS             31132..31419
                     /locus_tag="LY912_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBM6954240.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            31468..32250
                     /locus_tag="LY912_000521"
     CDS             31468..32250
                     /locus_tag="LY912_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBM6954241.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            32271..32978
                     /locus_tag="LY912_000522"
     CDS             32271..32978
                     /locus_tag="LY912_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBM6954242.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            33240..36038
                     /gene="ileS"
                     /locus_tag="LY912_000523"
     CDS             33240..36038
                     /gene="ileS"
                     /locus_tag="LY912_000523"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBM6954243.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(36087..37613)
                     /locus_tag="LY912_000524"
     CDS             complement(36087..37613)
                     /locus_tag="LY912_000524"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBM6954244.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(37628..38275)
                     /locus_tag="LY912_000525"
     CDS             complement(37628..38275)
                     /locus_tag="LY912_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBM6954245.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(38459..38788)
                     /locus_tag="LY912_000526"
     CDS             complement(38459..38788)
                     /locus_tag="LY912_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBM6954246.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            38965..39693
                     /gene="sfsA"
                     /locus_tag="LY912_000527"
     CDS             38965..39693
                     /gene="sfsA"
                     /locus_tag="LY912_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBM6954247.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            39709..40722
                     /locus_tag="LY912_000528"
     CDS             39709..40722
                     /locus_tag="LY912_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBM6954248.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            40722..41999
                     /locus_tag="LY912_000529"
     CDS             40722..41999
                     /locus_tag="LY912_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBM6954249.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            42062..44764
                     /locus_tag="LY912_000530"
     CDS             42062..44764
                     /locus_tag="LY912_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBM6954250.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            44916..45233
                     /locus_tag="LY912_000531"
     CDS             44916..45233
                     /locus_tag="LY912_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6954251.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            45263..45583
                     /locus_tag="LY912_000532"
     CDS             45263..45583
                     /locus_tag="LY912_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBM6954252.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            45691..47151
                     /locus_tag="LY912_000533"
     CDS             45691..47151
                     /locus_tag="LY912_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6954253.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            47219..47440
                     /locus_tag="LY912_000534"
     CDS             47219..47440
                     /locus_tag="LY912_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954254.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            47471..47653
                     /locus_tag="LY912_000535"
     CDS             47471..47653
                     /locus_tag="LY912_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBM6954255.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            47653..48066
                     /locus_tag="LY912_000536"
     CDS             47653..48066
                     /locus_tag="LY912_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBM6954256.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            48189..49370
                     /locus_tag="LY912_000537"
     CDS             48189..49370
                     /locus_tag="LY912_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6954257.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(49441..49605)
                     /locus_tag="LY912_000538"
     CDS             complement(49441..49605)
                     /locus_tag="LY912_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954258.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            49759..49832
                     /locus_tag="LY912_000539"
     tRNA            49759..49832
                     /locus_tag="LY912_000539"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49793..49795,aa:Arg,seq:cct)
     gene            complement(49901..51040)
                     /locus_tag="LY912_000540"
     CDS             complement(49901..51040)
                     /locus_tag="LY912_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBM6954259.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGLEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(51339..51974)
                     /locus_tag="LY912_000541"
     CDS             complement(51339..51974)
                     /locus_tag="LY912_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954260.1"
                     /translation="MDNRNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(52087..52722)
                     /locus_tag="LY912_000542"
     CDS             complement(52087..52722)
                     /locus_tag="LY912_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBM6954261.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQIEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(52756..53217)
                     /locus_tag="LY912_000543"
     CDS             complement(52756..53217)
                     /locus_tag="LY912_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBM6954262.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(53347..53778)
                     /locus_tag="LY912_000544"
     CDS             complement(53347..53778)
                     /locus_tag="LY912_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBM6954263.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(53796..54116)
                     /locus_tag="LY912_000545"
     CDS             complement(53796..54116)
                     /locus_tag="LY912_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6954264.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
BASE COUNT        17863 a         9162 c        11390 g        15768 t
ORIGIN      
        1 tttgtcacag ccttttttgt ttataaaaat aaaagttgta gtggaggcta cgaagtttac
       61 tttgtctttt tacacttaat atttttttgc caatttggaa tcaggatgtt ttgataacta
      121 tcgttttcaa ttgatggaag ctatattgtt tgctatcagt gaaataatta tatggtaaac
      181 agtgttcttt ttcttgtttc cattataaaa atcgtatcgg gatttttcgt tcttttaaat
      241 tgaacatttc tatctatccg cgtgttatca acaaaacaaa atcaggtaaa tagttgacga
      301 aacagaaata aatacatagt attatgtttt gaagcctaag tacaatagtc tatagaaaag
      361 gagcgatacc attggcaaaa cgcattgacc gaatttatat gtatgtcaaa gaaaaaaccg
      421 ctcatttaac aaaggcagaa tatgatcaag gagtaacaac acaggaaatt gctgaagtgt
      481 tagggattca gcgaacaaat agcagtaaag atctgaatca gctagtgcgc gaaggaaaac
      541 tgataaagac agacggacga ccagtacgtt acatatatca aacactcgtt acgcacgtaa
      601 agccagttac aaaacatgta gtcagttaca aagaaacgcc ggtctctgaa gaaaaaaata
      661 cactccaaat agatactaag gatatctttg caaaaatcat tggagctaac ggcagcatga
      721 aaaattcagt ggaacaggca aaagctgcga ttttgtatcc gccaagagga ttaaattgtt
      781 tgattacagg acctaccgga tcaggaaaga cttattttgc acacgcgatg tatcattttg
      841 caaaagcgca tcatgtaata gatgaggaaa cggaactgat tgttttcaat tgtgctgatt
      901 atgccaataa ccctgagctt ttgatgagtc atttatttgg gtacgcaaaa ggtgctttta
      961 caggcgcaga tgaagaaaaa atggggatta tcgatcaagc ggatggcggt atgctgtttt
     1021 tggatgagat tcaccggttg ccgcctgaag gtcaagaaat gatcttttac tttatggatc
     1081 atggaactta cagtcgtctt ggggaaacaa cgaaatccca tgaagcaaat gtacggatcg
     1141 taggtgcgac cacagaagac ccaggttctt ctctattaga aacttttgtt cggcgtatcc
     1201 caatcaatat caaacttccg gcttttgaaa aacgtcctgc aaatgagaaa gtcgatttag
     1261 taaaaatcat gattgcccac gaagcaaacc gcacgcagcg aaagatttct ttgacagaag
     1321 atgtagcaaa agcattgatc ggcagtgtga cctatggaaa tataggacaa ttgaagtcaa
     1381 atatccagtt agtatgtgca cgaggatttc taaatcatat gcaatcaccc gaaatctcga
     1441 tcacaatcga tgatttgaca gaagggattc gtagcggatt gattcaatta gcaagcaacc
     1501 gcagtgcaat ggcagagctt tctaaaatat tggagccaaa gataactgta gcaccaaatg
     1561 atacgatcat gaaaatccaa tcggactcct atgagttacc ttataatcta tatgatatca
     1621 tcggagataa agcagcttta ctgaagtcgg atggtttgga tcaagaagca atcaatcatt
     1681 tcatttctac agatatcaac atccatctga agtctttcta taaagaccat ggtttttctt
     1741 ttaatgcaga cagcaaatta gcagaatttg tagatccgaa aatcatagaa gtgaccaatc
     1801 agatttatgt aatggtcaaa agatctttac catatgagtt tcagcaaaac tttatttatg
     1861 ctatgagctt gcatatcagt tcttttttga aaaaaatcaa cttaggagaa gaacggcata
     1921 cgaatgataa catccgtgag atggcttttg attttccaga tgaatatgct gttgcgaaag
     1981 aagtgcgtag ttatatcgaa acgtattttc aagtggagat tccagaaagt gaagactatt
     2041 acttgaccgt tctactcgtc tcgttacggg caaatcaagc aagcggcaga atcggtgtag
     2101 tcgttgcagc tcacggaaac agcacagcaa gcagtatggt ccaagttgtc caacagttgt
     2161 tagatgcaga gaacgtacga gcagtagaca tgcctttgga tatggatccg aaaacagcat
     2221 tggaccgaat tgaacgcaat gtacaagaag tagatgaagg aagcggggtc atactcttag
     2281 tagatatggg gtcccttgcg tcgtttaatt cgcaaattca aagagacact ggaattccag
     2341 tacgtactgt tgatatggta acaacttctc tagttttgga aactgtacga aaggtctcag
     2401 tattagggac agatctagat atgttgcatg aatcattgaa aaattttcga ggttacgcag
     2461 aaatatcttc tgtagaatct gttcaggaag caaaacctat tcataagaaa aaagctgttt
     2521 tggctatctg cgcatctggc gaaggtacag cacaaagaat caaagaattg atcgaacgag
     2581 cggtaaacaa gcgtcaagaa acagaattag aagttctagc tttgtcgatt gtggaagtga
     2641 aagaagaact gccagttatc caaaaagaat atcagatcat agctactact gggattactg
     2701 atttgaatat ccaagcccca tttattcctt tagaacgttt tattgatcaa aatatcgaag
     2761 tcattttgga tcagttgctg atggaatcag aattggagga aactgaattc atctccctag
     2821 atgaagagtc agctaaaaat acgtgtgttg agtttatctc tgataacttc atctttatta
     2881 atggtagtaa gttaatcgat ccaatgtggc aattttctac acaaatctct cagacgacgg
     2941 gaatcggcga tgaagaatat ggattcaaaa tcaacctagt gatgcacaca gcaggaatga
     3001 tcgaacgtat tattcggaat gaaccattga ctgtggaaga aaacgaattg acaaatacaa
     3061 cgaatgatcc tctttatagc caattggcag cctcagttgt tctgttggaa gatcagataa
     3121 aagtaaaagt gccgatagaa gaaatgtatt atctgctacg tctagtccat aatcagttag
     3181 ataaaaaaga atacactgtg ccatgaatac acaaaaacga tacactttta tagtgtatcg
     3241 tttttgtgta ttggttaaga atcctttaaa ttcaattagt gtatcgtaaa aaagttggca
     3301 cgctttttgc ttatagtagt gtgtgctagg aggtggttgt tcacacagaa atgatagggg
     3361 tttctgtgaa gtagtgagga agaaggagtt ttgcagatgg atattcgatt ggcacgtata
     3421 gatgatcgtt taatccacgg gcaagtcgca acagtttggt cgaagcaaac aggtgttgaa
     3481 cgtatcattg tgatcagcga tgtagtcgct caagataaat tgagaaagtt tctactaaaa
     3541 gaagctgcac cgccggggat cacagcaaat gtaataaccg tgcagaaaat gattcaaatc
     3601 tatcatagtg gattattatc acgagcaaaa gtgatgcttt tattcaccaa tccccaagat
     3661 gttgaagcgg ttgtccgctg cggtgtacag ttgaagtcgt tgaatatcgg cggtatgagt
     3721 tttactgaag gcaaatcaat gattaccaat tttgtttcag taaatcaaca agatattgat
     3781 tcctttcgtt acttgaacag tcaagaagtg gagttagaga ttcgaaaagt acctgctgac
     3841 aggaaaatcc ttttgatgga actactagcg aaaatcaaaa aggtgtagca agaatggttg
     3901 ttggaaaagg tcaaataatt ctgttgtaat ggttagcaat tattaatatt tttgaatttg
     3961 ttacaacaaa agtaaatagg aggtataaat atggtaggga ttatcctagc aagtcatgga
     4021 caatttgctg aaggaatctt acaatccggt tcaatgatct ttggcgaaca agaaaacgtc
     4081 aaagccgtga ttttgaaacc aagtgaaggt ccagatgact tgagagccaa attggaagaa
     4141 gcggttgctt cttttgataa tcaagacgaa gtgttattct tagttgattt atggggcgga
     4201 acaccgttca atcaatcaaa cacattattc gaagagcaca aagataaatg ggcaatcgtc
     4261 agcggtttga atttaccaat gttgattgaa gcctacgcat cacgcttttc aatggaatct
     4321 gctcatgaaa ttgcagcaca catcattgaa acagcaaaag acggtgtaaa agtaaaaccg
     4381 gaagaattag aaccggcaga agcaccgaaa gcagcagttg aagacgcaca acctaaagga
     4441 gcacttccag aaggaactgt ggtcggagac ggaaaaatca aatatgtatt agcacgtgtt
     4501 gactcacgtc tgttacatgg acaagttgcg acagcttgga caaaagcagt gcaaccaaac
     4561 cgtattatcg ttgtttcaga tgcagtatca aaggatgatc tgcgtaagag actaatcgaa
     4621 caagctgctc ctccaggtgt aaaagcaaat gttattccta ttagcaaaat gatcgaagta
     4681 gcaaaagacc ctcgttttgg aaataccaaa gcattgcttt tatttgaaaa tcctgaagac
     4741 gtattgacag ctgttgaagg tggcgtagac atcaaagaat taaatgttgg gtcaatggcg
     4801 cattcggtcg gtaaagtcgt tgtaagtaaa gtattgtcta tgggacaaga agacgttgaa
     4861 gcgtttgaga agcttgaaca aaaaggtgtg aaattcgatg tacgtaaagt acctaatgat
     4921 tcacgcgata acatggatga tattttgaaa aaagcaaaag ctgaattagc aaaagcgtaa
     4981 taaataatat taaaatttat aggaggctta tcatgtctat tatttcaata attttagtcg
     5041 tattagttgc ctttctagct ggtatggaag gtattcttga tgaatttcaa tttcatcaac
     5101 cactagtggc atgtacattg atcggtttag ttaccggtaa cctcgaagct ggtatcgtac
     5161 ttggcggtac gcttcagatg atcgctttag gttgggcaaa tatcggtgcc gctgtagcac
     5221 cagatgctgc attagcatca gtagcatcag caattatttt agttttaggt ggacaaggtg
     5281 ttaaaggtgt tccttctgcg atcgcgattg ccgttccttt ggctgttgca gggttgttct
     5341 taacaatgat cgtacgtaca atcgctgttc caatcgttca tttgatggat gcggctgctg
     5401 aagaaggaaa catccgtaag gttgaaatgt ggcacatcat tgctgtatgt ttacaagggg
     5461 ttcgtatcgc ggtcccagca gcagcgttgc tatttatccc agcacaaact gtgcaatcat
     5521 tccttgaatc aatgccagca tggttaacag atggtatggc tatcggtggg ggaatggtcg
     5581 tagctgtagg ttacgctttg gtaatcaaca tgatggctac aaaagaagta tggccattct
     5641 tcgttattgg tttcgttgta gctgcaattt ctcaattaac attgattgct ctaggtgctt
     5701 taggtgttgc attagctctt atttacttga acctttctaa aatgggtggt tcatcaaata
     5761 atggaggcgg aagcaactct ggtgaccctt taggcgacat tttgaatgac tattaatctt
     5821 gaaggaggaa aataaaatgg cagaagaaaa aatcaaatta tcaaaaaaag atcgtttagc
     5881 tgttgcgtgg cgctctacct tcattcaagg ttcatggaac tacgaacgta tgcaaaacgg
     5941 tggctgggca ttttctatga ttccagcaat caaaaaatta tacaaaacaa aagaagaacg
     6001 ttctgcagca ttaaaacgtc acttggaatt ctttaataca cacccataca ttgcttctcc
     6061 aattttaggg gttacattgg ctctggaaga agaacgtgcg aatggcgcgc ctgttgatga
     6121 tgtagcgatt caaggggtta aagtaggtat gatgggtcct ttagctggtg ttggtgaccc
     6181 agtgttctgg tttacagtac gtccaatgct aggtgcacta ggtgcttcat tagctatggg
     6241 aggaaatatc cttggaccaa tcatcttctt cttaggttgg aacattattc gttgggcatt
     6301 catgtggtat acacaagaat ttggctacaa agctggttct aaaattactg atgacctttc
     6361 tggcggattg ttacaagacg taacaaaagg tgcttcaatt ttagggatgt tcgtattagc
     6421 tgcccttgta caaagatggg tatcaatcaa attcttacca gttgtatcaa ctgtaaaatt
     6481 agataaaggt gcttacatcg aatgggataa attgccttca ggtggtgaag gaatcaagag
     6541 tgcatttgaa caagttaata atggcttagc cctttctcct gaaaaggtaa caacattaca
     6601 agacaactta gaccaattga ttcctggttt agctgcatta ggattaacat tgttatgtat
     6661 gtggttgctt aagaaaaagg tttctccaat cgttatcatc cttggtttat tcgtagtcgg
     6721 tgttgttgga cacgtcatcg gacttttata atccataaaa atatagctcg ggcgttgtcc
     6781 cgagcttttt ttatatagta tactgttcat aaacaaatat ctggagggag aaaatggttc
     6841 aatcaatcaa tacaaaagta gacttggtaa ttgatgctac ttcgtttacg ggtctgacag
     6901 attacgggca aatcatgata ggtgataatg gttttgagtt ttaccatgcg cgagatagac
     6961 gcaaatatat ccaaattcca tgggaagaag tggattatgt actagcatca gtcatgctaa
     7021 agggaaaatg gattcctcga tatgccattc aaacgaaaaa aaatggtaca tacacatttt
     7081 cttccaaaga acctaaaaaa gtgcttcgtg cgatcagaga atatgtagat gaagatagaa
     7141 tggtacaatc attgagtttc tttgatgtag tgaaacgtgg tattcgtagt atgtttaaac
     7201 gcaagtaaaa aataaagaaa acttctaaga ggaggttttc tttatttttt tactttgcag
     7261 aagaaaatat gaaatagcaa aaccaattat ttgtcccctt taaatcccat atgctaaaat
     7321 tgattagcaa agaaggaggt tatattatga gttggttatg gacattgatt gttggagccg
     7381 tgatcggagc aattgcaggt gcgatcacca gtaaaggaaa ttcgatgggc tgtgtaacga
     7441 atatcattgc tggactagtc ggttcaagta ttggacaagc gattttcggc gaatggggac
     7501 caaaagctgc aggtatggca cttattccat ctattttagg cgcagtgatt ttggtagcag
     7561 ttgtctcatt tttctttgga aaacgatcat aagtttttac aaaatagtaa actaaaagga
     7621 gttgcagcga gactgtgact cctttttggc tttatttatt taaaataaaa agaagttttc
     7681 cggaaatttt tatttaactg tcgtgtacga agaaaagttt gctataatgg aaaaaagcgt
     7741 gcaaagaaag agggagtttc attatgatgc tacgtgtaga aaaattgcgc aaaaaaatgc
     7801 aagaagaaaa tttggattca tttttggtta ccagtccgta caatcttcgt tacttaacga
     7861 actttacagg tacgacagga ttagctgtta ttactttgga aaaagcattt tttattactg
     7921 attttcgtta taccgagcag gcggcagcgc aggctcaagg gtttgaaatt attaaaaatg
     7981 tcggacctat ttttgatgag gtagcaaact tagtacgcaa agaagaactg cactcattag
     8041 cttttgagga aacaacagtc tcatttttag aatattcggt tttagaagaa atcatcgatg
     8101 cggaattagt acctgtttca cagatgatcg aagaactcag agaagtgaaa gatgaagaag
     8161 aaatcgctat tatcgaaaaa gcatgtcata ttgcggatat ggcatatgat cacatcctga
     8221 aaatgatcca accgggcatg actgagattg aagtcgcaaa tcaactagac ttttatatgc
     8281 gttctcttgg cgcttcaggt gtttcttttg atacgatcgt tgctagcgga ttgcgttcgg
     8341 ctatgccgca tggtgtagca agcaaaaaaa tcatcgaaca aggtgacttg atcacattgg
     8401 actttggttg ctattacgaa gggtacgttt ccgatatgac acgtacattc gctattggtg
     8461 atcctgggga aaaattaaaa gaaatttatc aaatagtctt agatgctcaa ttagcagtta
     8521 ttgatgctgc aaaaccagga atgactggtg tccaattaga tgcagttgct agagattata
     8581 tttcaaaaca tggttacggg gaagcatttg gacattctac aggacatggg atcggtttag
     8641 agatccacga aggaccaaac gtttcttctc gtgcagaaaa gcaatttgta ccaggaaatg
     8701 tgatcactga tgaaccaggg atctacttac caggaatcgg tggagtacgt attgaggatg
     8761 acttgttgat cacagaagat ggaaatcgtg tgttgactcg ttcaccaaaa gaattgatca
     8821 tcttatagtt tcatcaatag aagaagtaag cgtaaaaatc agtgttcaca gactttgtta
     8881 tagaaaatca ctcgatttaa tgatacacta tagaagaact tttaagctgt aagagataat
     8941 aaagttgggt gttttctcca attcatagca gtttgcagct gatcggcggc agttttctta
     9001 ccacgtgatc actatgccgc atcatagaga attcggatgt atctcgtgct taggcaaagg
     9061 gaggaataaa taaatggcag atgaaaaaaa tttgatttta aacgcaaacc aagatttagg
     9121 agagatcgtg atcgctcctg aagtcatcga agtaattatc gggattgcag cttctaaagt
     9181 agaaggcgta tacggaatgc gcggaacttt tgccagcaat gtcactgaat tattaggacg
     9241 tgcagctcac ggaaaaggtg tttacttagc aaacgaggaa gatggcttga aagtagatct
     9301 ttactgttat ctagaatatg gtgtttcagt tcctaaagta gcaatggaaa tgcaggaacg
     9361 ggtcagccag caagtccttt tcatgacgga tatcgattta tctgaagtca atatccatgt
     9421 agtagctgtt gttcctgaaa aattagaaca accaacaatc gaagaacttt ttgaagacga
     9481 agaggaagag aatgaataaa gaattatcaa gacacgagat tcgggaaatg gcattgcagg
     9541 ctttatttcc attagacttc aatgcagacc taacaaaaga agatgcgatt ttcaacgcaa
     9601 tcgaattaga ccaccgcgac atgatcaacg aagatgaatc agagtttgtt cctgtttatc
     9661 ttgatacgct agttggcggt gtctgtgcaa aaaaagatga attggataaa gtgattgaaa
     9721 aacatttaaa aaacaattgg cacatcaatc ggatctcaaa aatggatttg gtgatcttgc
     9781 gtatcgcgat ttttgaaatg acttatgtga cagatgtacc agcggctgtt gctttaaatg
     9841 aagcaatcga gttggcaaaa acatttagtg atgaccgttc acgtaaattc gtcaacggtg
     9901 ttttatccaa tgtattgaaa gaattagaag ctggggcgta agtcctagct tttttctatg
     9961 aatcatcata aacctgttat aaatcgggaa aattctatgg tagaatgaaa acacaaaaaa
    10021 tatctgggag tggttagatg gcagaattga ttaacggaaa agaattagct gaaaaaatgc
    10081 aggcagagat tgctgaaaaa atccaaaaat tgaaagataa tggtatccat cccggattag
    10141 tcgttttatt ggtaggggaa aatccagcca gccaaatcta tgtaagaaat aaagaacgtg
    10201 tagcaaaaga aatcggaatc cattcattgg tagagcgtta tcctgagacg atttctgaag
    10261 acgaactact tgcagaaatt gaaaaataca atcaagatcc tagttttcat ggtatattgg
    10321 tccaattacc attgccaaag catatagatg aagaaaagat cctgttagct atccgccctg
    10381 aaaaagacgt agacggtttt catccgatga atttaggcag actccttgcg ggtaaaccgg
    10441 acaagattcc ttgtactcca tacggcatca tgaaaatgtt tgaagcttat tctatcgatc
    10501 cggcgggtaa acgagcagta gttatcggac gaagcaatat cgtcggtaaa ccgatggctc
    10561 agctactctt gatggcagat gcaactgtta ctgttgctca ttctaaaacc gaaaatctgg
    10621 ctgaactggc acaagaagca gatattttag tcgtagcaat aggacgtgga cattttgtca
    10681 caaaagaatt cgtaaaacca ggtgctgtag tgatagatgt agggatgaat cgtgatgcta
    10741 acggtaagct gatcggtgat gtgaaatttg atgaagtgga gcctattgca ggctggatca
    10801 ctcctgtgcc aaagggtgta gggccaatga ctatcacgat gctgatgtat caaaccgtaa
    10861 aatctgccga agcttttgga gcaggtgaat agatggcaca agaatattta actgtcacta
    10921 cattaacgaa gtatttgaaa agaaaatttg atgccgatcc ttatttagaa cgcgtatatt
    10981 taacaggcga aatatcgaat ttccgtttac gtgccaatgc ccatcaatat ttcagcttaa
    11041 aagatgacca tgcaaaaata tctgctatta tgttcaaagg agcattccaa aaattacgat
    11101 tccagccaaa agaaggaatg aaagtccttg tcgttgggcg tatttcatta tatgaagcgg
    11161 gaggttctta tcaaatctat gtagagcaca tggagcctga tggaataggt gctttatatc
    11221 aagaattgga agaacgaaaa gaaaagctga tgaaggaagg cctttttcaa gggcctaaaa
    11281 aaatgctgcc acgtttccca aagcgaatcg cggtccttac cagtccaagc ggagcggtta
    11341 tccgcgatat catcacgacg gtgaaaagaa gatatccaat tgtccaattg gttttgttcc
    11401 caacagttgt acaaggaaac caagcagcgg acaatgttgt caggaatatc cagagagtag
    11461 aagagatggg caatttcgat acaatgatca tcggtcgtgg gggtggttcg attgaggatt
    11521 tatggccgtt taatgaagag cgggttgctc gggcgattta tcaagctaat acgccggtga
    11581 tttcatctgt aggacatgaa acagatacca cgatcgctga tttagtagca gatgttcggg
    11641 ctgccactcc aacagcagct gcagaattag ctgttcctgt tttgtcagaa gagttgatgc
    11701 gcattcaaga acggcaagct agattgcagc aggcgtttgt acgccagatc cagcgcaaac
    11761 aagaacggtt cgagcgtgct cgacgttcct atgtatttcg gcagcctgaa agattgtatg
    11821 aaggtcagac catcaaatta gaccagttga aacagcgatt atatcaagct acacagcaaa
    11881 tttatcatgc gaaagaaaaa caaacgatcg cattaagcca ccaattggaa caagtggctc
    11941 cgctttatcg agttaaagca gctcgccaag aaactgctta tctagaaaaa cgcttagaag
    12001 agaaaatcca acaatatatg aaacaacagc agcagcgttt tgctcaagct gttcaatctc
    12061 ttgatttgtt gagtccattg aaaatcatgg gaagaggcta cagctatacg acgttaaatg
    12121 atcaagtagt aaaaagtgtc accgagattc atcaagggga tttgctgacg atccattatc
    12181 aagatggaat cgttaaagga caagtacaag agatagacaa aggagaataa aaatatggaa
    12241 aatccaactt ttgaagagtc actgcaagaa ttagaaaaaa ttgtcatgca gttagaacaa
    12301 ggagacgttc cattagaatc agctctagat tcgtttaaac gaggaatgga attaagcaaa
    12361 cattgccaag atacattagc taaagcagaa gagaccttga cgaaaatgat gacagaatca
    12421 aatgaagaag ttgattttga cggaaacgag gaaagctgag atgagattaa ctgacttttc
    12481 agctattcat ctacctgctg tagaaaaaga aatcttgtct tttttagatg agcatacaac
    12541 ggatagagga ctctatgatg cgatgagtta ttcagtgaaa gcaggcggga aaagaatacg
    12601 tcccttatta cttttaacgg ccgttgcttc ctttgatgag cctattgatg ttcccgtcta
    12661 tcaagtagca gctgctttag aaatggtgca tacgtattcc ttgatccacg atgatttgcc
    12721 tgcgatggac aatgatgatc ttcgtagagg aaaacctacc aatcataaag tattcggcga
    12781 agcattagct atattggccg gagatggttt gcttacagga gcattccagc taatcagtat
    12841 ggcacactta ggtaattctc ctaagcttct gctgcttcag caattagctg tttgtgcggg
    12901 atcacaaggt atggttgctg ggcaagctgc agatatcgag ggcgaatcga aaaagctttc
    12961 tttagaagaa ttagcattta ttcatgaaag aaagacaggg catttgattc gttatgcctt
    13021 gctggctggt ggcatattag cgaagcaacc tgaagaaatc ttattgctac ttcaacgatt
    13081 agccgaacat ttaggtttag cttttcagat aagagatgat ctactcgatg tgattggtac
    13141 aacgaaaaca ttagggaaaa cagctggtaa agatgaacgt atggaaaaaa atacttaccc
    13201 gcgtttatta ggcctagaaa agacacgtga ggcgttggag attgagctgt tatccgccaa
    13261 caagatcata gacaaattag aagaggacgt tttttctttt gatggcgggc tgatgcgcca
    13321 gatgatcaag caatttgatg tggagaaatg agggaaagaa tggaaaaaga acgcgtagat
    13381 gtattagcgg tcaaacaagg attatttgaa acaagagaac aagccaaacg ttcagtgatg
    13441 gctggtttga tttacaacga aaaaaacgag cggtttgata aaccgggaga aaaaattcca
    13501 gtgagtagtg aattaagagt caaaggtaaa aaacttcctt atgtttctcg agggggatta
    13561 aaattagaaa aagcactcaa agcatttgat ctatctgttg aaggaaaaac attgttagat
    13621 attggtgcat ccactggcgg atttactgat gcagctttgc aaaatggcgc aaaaatgagt
    13681 tatgctttag acgttggcta caatcagcta gcttggaaaa taagacaaga tcctagagtc
    13741 gtcgtaatgg aaagagtgaa ttttcgttat gcaaaacccg aagactttac cttaggaatt
    13801 ccagaagttg ctgttatcga tgtttctttt atttcactaa aactgatgct gcctccatta
    13861 catgctattt taaaagaaga gggagaagtg attgctttaa tcaaacccca attcgaagca
    13921 ggcagagaag ctgtagggaa aaacggaatt gttcgtgacc ctcagaccca tcaaaaagtt
    13981 ttagaagaca ttttgtcatt tgcggcacaa ggtggatatg atgtgctgga attaagttat
    14041 tctccgatca cggggggaga aggaaatatc gagttcttgg ctcacttgag gaaagtaccc
    14101 gaaagcggaa caatcaattc agctattaat atggcagaag tggtttcaaa tgcacacgaa
    14161 cagtttgacc ataaataaat tgtaactgtg aaaatcaagt gagaagtatg cggattcttc
    14221 tttattatac caaggaaata agctatcatt gattaagaag aatatgctaa ggagcgaaga
    14281 cgtaatgaga aaaaaagatc ggcatcgttt gattactcga ttgttgagtg agcaagatat
    14341 ccgaaagcag gaagaatttg ttgaaatcct gaaaagcaaa ggaatatctg ttactcaagc
    14401 tacgatttcc agagatataa aggaactgaa actgatcaag gtaccggctt cagatggcgg
    14461 ctaccgttat agcataccag ctgaaacaaa cgaagatgta aatactaaat tggaaaaact
    14521 attaaaagac gctttcgtgg cagttgacca aatggaaaaa tttgttattt tgaaaacatt
    14581 gccgggaaat gcttcggcag cagcaaattt gattgataaa cgttacaaga aagaattatt
    14641 ttcgattatc aatgatgacg ataatgtttt gatgattaca cgaactgaag accaggcagt
    14701 tttattgaag aaagacttcc tgcattacct ttaagttgag gagcgaatgt gatgctacaa
    14761 gaaatcagta ttactaactt tgcgattatt ccggaattgc ggctttcttt tcacgaagga
    14821 atgaccgcgc tgaccggaga gactggtgcg ggtaaatcca ttattatcga tgctttaggt
    14881 ctgttagcag gaggaagagg ttcaagcgat tatatacgtc aaggagcaga aaaatgtgtg
    14941 cttgaagggt tgtttgaact accaaaacaa gaaggattct ctgaactgat ggttgaatta
    15001 gggatcgaaa cagatgagga caatctgatt gttcgacggg atatgtcctt aactggaaaa
    15061 aatgtttgtc gagtgaatgg tcatattatc acattagcta atctgagaag aatcggcagt
    15121 tatttagtag atatccaagg acaaaacgaa catcaggaac tgctccagcc tgaatcacat
    15181 cttgctttat tggatcgttt tggagatgta gctttccaac agaagaaaaa gagttatcag
    15241 caagaatata tctcttatcg tgagctggaa aaaagggtac gaaaagtgca gcaaaatgaa
    15301 aaatcctatg ttcagagaat agatatgctc catttccagc aagaagaaat agctgctgct
    15361 gatttgcaag tcggagaaga agagaaatta aaagaagaaa gagaaaaact tagcaattat
    15421 caaaaaattg ctgatggatt agctgcaggt tacggagcac tgacgaataa tgaacaaaac
    15481 agtgtagatg gtgttggctt ggccgtttca gaactgcaag ggatcgccca tctagatgtg
    15541 gagtatgaag caatttatga aaatatccaa agtgcttact atttgctgca agatgcaatc
    15601 ggcgatatga gtcgtcagat tgatttattg gagttagatg agagtcgttt agaagaagtt
    15661 acgcaacgtt tagaattaat ccgacagttg aaacgtaaat acggcgaatc cattgagtca
    15721 atattggctt actatgacga aatcaccgaa gagctagctt cttctgattt ttcagaaggt
    15781 caattggaca aaatgaaaga ggaactagag caaaaagagc ttctacttca gcaacaagcc
    15841 gcagatcttc atgaagcgcg taaaaaaatc gcaaaagaat tggaaaaatc cattctgcat
    15901 gaattgaaaa gtctgtatat ggaaaacact gagtttgagg tacgtttctt aaaagaagaa
    15961 aatagacaat tgaatcatga tggatttgac caaatcgaat tttacattac gaccaatcca
    16021 ggagagccac tgaagccttt ggtgaaagtc gcttctggtg gcgaactgtc tcggatgttg
    16081 cttgctttga aaactatttt ttcttctgag caaggtgtga caagtattat ttttgatgaa
    16141 gtggatacag gtgtgagcgg aagagttgca caggccatcg cagataaaat ttctcaaata
    16201 tcgaaatact ctcaagtttt gtgcatcact catctgcctc aagttgctgc agtcgccgac
    16261 tatcaatatt atattgtgaa agcagtgatt gatggacgta cgcaaacttc tgtttcagag
    16321 ttgaaaacaa aagaaagaga agaagaaatt gcacgtatgc tggctggaag tgagattaca
    16381 aaactcacac tcgaacatgc aaaagaacta ttgaaactcg caaaaaggac ctgagccacc
    16441 tcgcagtggt tcaggtcctt ttcagcagct gatagctata ttttattttt acatgacact
    16501 cattacagca gtcaatacaa cagatccaat cgttaaaatc agcattgtcc aaatgacaaa
    16561 ttttgttact ttagcaaaag tacttgtttg ttttttttca cgcattgttt tcaacctcgt
    16621 cattaattag ttgattcaag tgtacaatct tttttccatt tccacaagag ggctttttta
    16681 taaaaacttc ccttttttta aataataggt agttacgata caaataaata atgttaatag
    16741 aactagccat ataaaggcat catccctttc agcaataggt aacttaatgt tcattccata
    16801 gatactgccg acgattgtcg gtatagttaa aataatcgtt aaagaagtta aaattttcat
    16861 aatattattc agattattcg atacgattgc tgaaaaagtc tgattcattt gttctactag
    16921 ttttaattga atgcgagaag tagtcattgc ctgctctgtt tccaccaata catcacgtaa
    16981 atgatttttc aaagcatgat tttcttggaa aagtttattt tgcgctagtt ctttcaatgc
    17041 atctaaatta gcagaagtcg cttctctgaa ataaacgagg cttttttgga tatccatgat
    17101 ttgataaagt tgtttgtttt cagtggatac ttgaagtttg gcttccaaag tatcgcattg
    17161 agattgaagc gtagctaaat aactgttgta agagagtgtg acctgccaaa tgaattgaaa
    17221 gaagatattg agattaggcg aaatatcact ttttggaaag gtctggctaa agactttctt
    17281 taaaaacagt ggttcatgat tcgtaattgt gataagcttc tttttgggcg tcaaaataat
    17341 agagagcggg tatgtatcca cttgaaaata accgctagga cttgttttag caaaaggata
    17401 ttgtaacaat aataacgctg gctttgtcaa ctttgattga ttgaattctt ctgtacggga
    17461 attttctgca tcgtccaata tggaagtgat gtaatctgac ggaatttcaa attgatgtgt
    17521 cagctgatga atctcttctt gattaggacg ttctacacaa taccagatcg tttggtcagt
    17581 ttcctttccg gtattacgca gtttctcatt atctaatgta aaatatttga tcatgatttt
    17641 cctcctgttg cctgtttctt ttattataac ggatagggaa ttggaataca tggaatgtgt
    17701 ttgtaagata tagaatataa ctgcataaat ttaaataaaa tgaaacagtt gtgtaaagta
    17761 tatacagtat acttgaagca acgataaaaa aggagtttac gttcatgggc acattcacac
    17821 cacttatctt gttttggtat atttacccgg taatcgtttt gtttggttgc caatttcttg
    17881 taaaattatt ttcgttaaat cgtcgtttta aaataaaagc ccctgatttg gcgattcctt
    17941 ttttgtgggg cggtatgcat gcattgtcta gaaatacagg gacaatttct atcttaccgt
    18001 ttttctttat ttctgttttg ctaatgggaa tttgtattgc tgttttccaa gcatattatt
    18061 atgaagaaat tatttatccg cgttatttca agatgacttg gcgtttggtt tttctgttga
    18121 caatcgtctt gtacgctgtc ttgatcattg tgaacatact ttcttaccta tgaaaaaaat
    18181 agaaaagctg taaaaagtct tttaaaaggc tttttgcagc ttgattttta aaaaaatgtt
    18241 tatgaataaa aaaagttgtt cccggatttc ccagaaaagg tggtagaaag tgggggattg
    18301 tggtagacta attttagtta gtggaggaat ggggggcttt caatgttgat gggtgaattc
    18361 caacataata ttgatgcaaa aggacgttta atcgtgccct caaaacttcg tgaagaactt
    18421 ggcgaaaagt ttgttctgac acgcggattg gatggctgtc ttttcggcta tccgatgagc
    18481 gaatgggaaa atctggaagc taaactgaac gaaatgccgt tggctaaaaa agacgcacgt
    18541 acttttgtgc gattcttcta ttcggctgcc actgaatgcg aacttgataa acaaggacga
    18601 atcaatatac ccagcacgtt aagaaattat gcagctttga caaaaggttg cgtagtcatc
    18661 ggtgtatcta accgaattga aatttgggat gagacacgat ggcaagattt ttctgcagca
    18721 gcagaagaga actttgacga aattgctgaa agtatgattg atttcggact ataagaatag
    18781 gaagaggctg actaatgact gaaacatttc aacactatac agtcatgttg aaagaaacgg
    18841 tagatggatt gaacatcaaa ccggatggcg tttatgtaga ctgtacactc ggcggtgccg
    18901 gacatagtga atatttatta agccaactaa gttctaaagg gcatctgtat gcgtttgacc
    18961 aagatcaaaa agcaatcgat cacgccaagc tgcgtttagc ttcttatgtc gaacaaggta
    19021 tggtcacatt tatcaaagcg aacttcagag aattagaaga acgcttgagt gagcatgtag
    19081 ataaggtaga cggcattttg tatgatctag gggtttcctc tccccagcta gatgaagcag
    19141 aacgtggatt tagttatcat caagatgcac cgttggatat gcgcatggat cagtcagctc
    19201 ctttatccgc ttatcacgta attaatgaat attcctacca tgaattagta aagattttct
    19261 tccgctatgg cgaggagaaa ttttccaaac aaattgctcg tgaaatcgaa cgagtacgaa
    19321 aaacaaaacc aatccaaaca actggtgagc ttgtcgaaat cattaaacaa gtcatcccag
    19381 ctcccgcaag aagaaaaggc gggcatcctg caaaaagaat ttttcaagct gtgcggattg
    19441 cagtaaatga cgaactcggt gccgaagagg cctctttaga acaggcaatc cggttattga
    19501 aagtcaatgg aagaatcagc gtaatcacat tccattcatt ggaagacaga attgtcaaaa
    19561 gtatgtttaa agaatatagt acggtacaag atctaccacc gggacttcct gtcatacctg
    19621 acgaattcca accagaactg aaagtcatta ctcgtaaacc aatccttcct tcagaggaag
    19681 agctaacaga aaacaatcga tcacgcagtg caaagttacg tattgcagaa aaaataagaa
    19741 tgaaagagga gtagaatgat ggcagaatta aagaaaatgc aagattacga atatgattta
    19801 cctgaattgg tggatcagcc ggaacaacaa atgcctgatt cttcttcgaa tcaagaaatc
    19861 attcttccac aatcaccggc aaaacgatta aagcagattt ctgctttgga aaaaattgct
    19921 gtggcaagcg tggcgattgc tattgttgct ttatgtgttt taacagttat gctgcgcaca
    19981 aatatcagcg gagctgaaaa agaaatcacg tcaatacaaa cagaaatcaa tgataaaaag
    20041 caagaaaaaa cgagtttaga acaagaaaaa aacgaacttt ctcgtactga acggattaaa
    20101 caaatcgcag aagaaaaagg attgtctatt aatgacgaca atttaaggaa agtgaagtaa
    20161 atgagtctta aaaataaaat tcggcggttt atggaaaaga aaaatctaaa tccgatgaac
    20221 aatcgcaaaa aagtaggtat cattttattt gctacgagta ttggattgtt ctttttattt
    20281 gccgtccgtt tctcgtatat cgttattgga ggtcatgttg ctggtacctc attagctgaa
    20341 aaaacaaaac agttgtacca aggaagtgaa gtagtaaaag caaaaagagg aacgatttat
    20401 gatcgtaacg gtgtggcgct cgcagaagat gcctcctctt attcaattaa agcgatactc
    20461 tcaaaaacat atacctctgg ggataaaaaa ctgtatgttg aagaaaagaa ttttgataaa
    20521 atagcagaaa tcctgcataa gaatctttct atagacaaaa aagatgcact gaatatttta
    20581 gaggacggcg caaaaaaaga gctgtatcaa gttgaatttg gtagctatgg gaaaaatatc
    20641 tcccaagaaa ccaagcaaaa catcgaagcg gacatgaaaa aagaaggtgt cgctggtctt
    20701 tattttgtcg accatcaggc tcggatgtat ccaaatggcg tcttttcttc tcattttatt
    20761 ggatacgcag ttccagacaa agatgagaat ggcttagttg gtaaactagg tttggagtct
    20821 gcttacaatg atatcttgag cggtaaagat ggtaagatta tttatcaaaa agataatttt
    20881 caaaatcctc tgccaggtac agtggcagaa gaagaaaaag ctgtcgacgg acaagatatc
    20941 tacacgactt tagacagcag actacaaagt tatttagaaa cactgatgga tcaagtaaat
    21001 gaagaatatc agccagaaga attgacagca gtcctgatga aagcaaaaac cggagaaatc
    21061 ttggcaatgg gacaacgacc tactttcaat cctgaaacaa tggaaggatt gactggaaaa
    21121 gatgctatct ggcgtaattt cttggtacaa gatagttatg aaccaggatc aaccatgaaa
    21181 gttttcacta ctgcagctgc tatcgaagaa ggagaattca acgagaatga aaccttccaa
    21241 tctggaaaaa tccaagtaga agatgctacg atcaatgacc atgactttgg tgaaaaaggt
    21301 gtgctgacca tgcgtcaagc tctttcatgg tcaagtaacg tcgggatggt catactggaa
    21361 cagcgattag gcggacgatg gtataactat ttacaaaaac tgggatttgg acaaagtact
    21421 cattctggat tagatgatga agtaaacggt gctttaccta cattaaatat tgtcgaccga
    21481 gcaatgagtg cttatggaca agcggtaggt gtgacgaatt tccaaatgat gaaagctttc
    21541 acttctattg cgaataacgg tacaatgatt caacctcgat atatcagcaa agtggtggat
    21601 ccccaaactg gagaagagcg aacaactcaa acagaagttc tagggcaacc tttttcaaaa
    21661 gaaacaacag aaaaagtccg tgaatatatg agagatgttg tcgaaagcga aaactacggt
    21721 attgcttatg gtgtatatag tgtacctgga tacaatgtat cggcaaaaac cggaacagcc
    21781 caaatcgctt ctgatacagg gggatatcaa acaggagata cagcctacct gtattcgatt
    21841 gtggagatgg ttccttctga agatccagac tatgtcttgt atctaacaat gaaacaccct
    21901 aagacatatg atcgaatggc attggctaaa atcgcaaatc cattgatgaa acgggcaatg
    21961 gattttaaag aaactgaaga agattcagat acagaaacaa aaacagaaaa agtatccgta
    22021 gccgattatc gtaatcttga agcggacgtt gcagcagctg atgctcaaaa aagtggactg
    22081 caacctgtag tgatcggtaa tggtaaaaaa gtacaaaaac aatctactgc caacggtgat
    22141 cagttgatct ctggagaaaa actgatccta tatactggtg gtgataagct gatgcctgac
    22201 gtaacaggat ggtcaaaagc agatatcatg aagctgggga aaatcctcgg tattgaagtt
    22261 agttttgatg gagatggtta ttgtgtcaaa caagaacttg ctccatatga aaaaatcact
    22321 gaagacaaac ttagttttac tttagaagaa taagaagaga aataggagag aaaagagcat
    22381 ggaatggaca caagcattga ttcccattgt cagcagttgt gcaatgacaa ttgccgcaat
    22441 gccgctattt attggttatt ttcaaatgaa aaagcaaggt caggcgattc gtgaggaggg
    22501 accaaagtgg cacaatagca aagccggaac tcctacaatg ggcggcttag tgtttctgat
    22561 cggctctatt ttgacaggaa tttgggttgg agcttggcaa aaacagctaa ctcctactct
    22621 tttcatcttg ctttttgtat tagcgttata cggagtaatc ggctttcttg atgattttat
    22681 aaaaatattc aagaaaagaa acatgggact gaactcgaag cagaaattga ttggacagat
    22741 tctaggggga atcatctttt atcttgttta ccgttctgaa ggttatccag gtgtattgaa
    22801 tttcttcgga ctagatctac ctttaggaat catttatggt attttcgctc tcttctggct
    22861 tgttggattt tcaaatgcag taaatctgac agatggcatc gatggattag ttgctggctt
    22921 aggaagtatc tcttttgcag cttacggtct aattgcttgg catcagcatc agtatgatgt
    22981 attaatcatt tgcttaagtg ttttaggagg tttactgggt ttcttcgtct acaacagaaa
    23041 acctgccaag atttttatgg gagatgtcgg ttcattagcg ttgggcggac ttttagcggc
    23101 aatttctata atgctaaacc aagaatggac attgcttttg attggtttga tctatgttat
    23161 ggaaacagca agtgtgatgc ttcaagttac ttcctttaag cttacaggaa aacgaatttt
    23221 taaaatgtct ccaattcatc atcactttga aatgtgcgga tggtcggagt ggaagattga
    23281 tacagttttt tggttgatca gcattgtgac ttcgttgatc acattatgga tcgtttggta
    23341 ggagatgacg ggaaatgaaa aaaatatcaa catatgaaaa taagaaagtg cttgtcttag
    23401 gactcgcaaa aagcggagta agtgcggcca aattattaca tgaattgggc gcacttgtca
    23461 ccgttaatga tggaaaacct tttgacgaaa atccggaagc acaagagctg ctttctttag
    23521 ggataaaagt aataacaggt agtcatccaa tcgaattgtt ggatgaagaa ttttcattga
    23581 tggtcaaaaa tccagggatt ccctacagtc atcctttagt agcaaaagcc caagaaatgg
    23641 gtattccggt aattacggaa gttgagctag cttacgaagt agcggaatgc ccaattattg
    23701 ggattacagg aacgaacgga aaaacaacga caacaacgat gacaggacta ctactgaatg
    23761 caggagcaga tcaaggaatt gcacgtttag cgggtaatat tgggtatcca gcaagtggtg
    23821 tagcgcaaga agcaaaatca gaagataaaa ttgtgatgga attgtctagc ttccaactca
    23881 tgggaatcac agatttccgc cctcatatag cggtgattac caatatctat gaagcacata
    23941 ttgattatca tggtacaaga aaagaatatg tcaaagctaa atggaacctt caaaaaaaca
    24001 tgacagaaaa agattatctg atccttaact ggaatcagtc agaactacaa gaattagcgc
    24061 aaagaacaaa agcacgcgta ctgcctttct cgacaaaaga agtgttggaa gacggtgtgt
    24121 atgctgacga ttactcaata tactataaaa aagaaaaaat aatggaaata tctgaacttg
    24181 gcgtaccagg taagcataat gtagaaaatg cactagctgc tatttctgta gcaaaattgt
    24241 atggtatatc aaatgaagct atacgagaaa cgttgcattt tttccatggc gtaccacatc
    24301 gtacgcaata tgtaggagaa atccaaggca gaaaatttta taatgattca aaagcaacca
    24361 atattttagc gactaaaatg gctctaagtg gatttgaaac gtctaaggtc gtgttattgg
    24421 ctggcggatt agacagagga aatacatttg atgaattaat tccttcatta aaaggaatca
    24481 aagcaatggt cgtatttggc caaacaaaag aaaagttgat ggatgctgga aaaaaagcag
    24541 gcatcgagac aatagtaaca gccgattctg tagaacaagc agttccttta gcattagaaa
    24601 acagtacaga tggtgatgta gttttattat caccagcgaa tgccagctgg gatcaatacc
    24661 caaattttga aactagagga aacagattca tggaagctgt gaaccgatta aaatagaaaa
    24721 agtagaagcg agcgataaaa aatgaaaatt ttggttacag gcggaggaac agggggacat
    24781 atttatccag ctcttgcctt tgtcaattat gtaaagactc aagaaccgaa tgctgaattc
    24841 atgtatgtgg gagcaaaacg aggtctagaa aacaaaatcg tccctgatac aggaatgcct
    24901 ttccatacct tggagattca aggatttaaa cgaaaaattt ccatgcataa catcaagacg
    24961 gtccgattgt ttcttaagag tatccgtcaa gcaaaaaaaa tcctcagtga ttttcaacca
    25021 gatatcgtta tcggtactgg aggatatgtt tccggagcgg tagtgtacgc tgcagccaaa
    25081 atgggtattc caacagttat ccatgaacaa aacagtgtac caggtgttac caataaattt
    25141 ttaagccgat atgtggatcg gatcgctctt tcatttaaag atgcggcttc cttttttcct
    25201 gaaaacaaag cagttcttgt aggtaatcct cgagcacaag aagtagcaga tactaaaaaa
    25261 tcagatattt tgaaaacatt tgatttggat ccagaaaaga aaacagtctt gatttttggc
    25321 ggtagtcaag gagcacttaa aatcaatcaa gcagtatcag tttttttaag tgaatatatt
    25381 ccttcttctt accaagtttt gtatgcttca ggagatagat attatgaaga gatcctaaat
    25441 aaaataaatc ctgaaataca aaatattagt gtccagcctt atatcaaaaa tatggcagag
    25501 gtcatggctt ccagtgatct gctggtgggg cgtgctggtg caacttcgat cgcagaattc
    25561 acagctctgg ggttaccggc agtgttggtt cccagcccat atgttacgaa tgatcatcag
    25621 actaaaaatg caatgagtct tgttcacgca ggagcagcaa aaatgattgc agataatgaa
    25681 ctaacaggtg aatcactaag tcagacagtc aacgaaatca tgggtgatga agaattgcaa
    25741 aagcaaatgt gccgagcttc taaagaacaa ggaatccctg atgcttcaaa acgtctttat
    25801 gacttagtaa aacaaataat caaaaaataa aggcggtggt cttagtgagt aagaaaaaag
    25861 aaccaaaaaa attgtctcat ccgtcttctg atgaaaacaa tttgactcct tggcaaaagg
    25921 ctaaccgaaa atatctggca gaacaagaga tgaaaaacca agagccaaaa aaagaagaca
    25981 taacattaga tacacccctt tcagattctg aagaagaaaa aacggttcaa gaggaacagc
    26041 aagaagaaag ccagtccgag aaaaaaatcg aattttttga agagatcaag caaaagaaaa
    26101 acggtggacc atataacggt tcttttttga accggctgcc caatttaaaa agtcaacggc
    26161 acaaagtact atttcgtcgg ttagctttga tcatcactgt attgggtata ccgctgattt
    26221 ttttgatcta ttatgtttct ccttatagca aattacaagc agttgcagta tcaggcaata
    26281 agacagtcaa cagccaagaa atcatctctg atacaaaatt gtcattagga gaaaatgttt
    26341 ggggacagta ttttcatcga tctacttata tcgatcgcct taaaaaagca cagccaagaa
    26401 tcgaaacagc aaatatacat ttcaaaggga tgaatgaatt cgatttggat gtaacagaat
    26461 ataaagagat tgctttgatc gcaaaaaaca atcaatacta cccagtgatt gaaaatggaa
    26521 cagtattaga tgaaaaagta gcaaatccta caaaaaatct ccctatcttg gaagagttca
    26581 aagactctgc aaaaatcaaa gaattaacaa agcaatacaa tcagttatca tcagaattac
    26641 aaaaagcaat ttctgaaatc aagtacacgc caagagcaag caataaaaat ctgatccaat
    26701 tgaatatgaa tgacggcaat caagttattg taaatatcaa taatcttgcg aaccaaatga
    26761 aatattattc gcaagtagcc aaagatatgg atgaaaaagg tgtgatcgac atggaagttg
    26821 gtatcttctc gcatccttac ggtagcactc aagaaacgga agaatcgggc caatcggaag
    26881 aaacaactga aagtgaagaa aatgcggatc aaacaaacga atcaagtgaa gaggcagaaa
    26941 cgcaaaaagc acaaacacct ggatcgtcta gcacaaacgg atcatctgat tcaaatgatt
    27001 caagtgaaac aagtcaaata gaagataatc caagtacaac tccgtcaagt ttaaatgaaa
    27061 attgataaaa caactttaaa aagtaagaat gtactttcta aaaaccagta atttatggta
    27121 gaattggaag cagtgaatat atctattaat aagtatattt taaaacggac gctagttgtt
    27181 cgcttgtata tggaatagta agtaggaggg aatcccattc atggcaaaaa caggaatgta
    27241 tgtaggcctt gatattggaa cgacatctgt taaagttgtc gtggctgaat atatcgacag
    27301 ccaaatgaat attattggag taggaaacgc aaaatcagaa gggattaacc gaggcattat
    27361 cgttgatatc gataaaacgg tccaagcgat acaacgagca gtacgacaag cagaagaaaa
    27421 agcaggtatc cagatcaaag gcgtaagtgt cggtttgcca gcaaacatgc ttgaagtaga
    27481 aaattgccag ggaatgattg cagttaacgg agattcaaag gaaatcaccg atgaagatgt
    27541 cagaaatgtg gcttcagctg cccttgttcg ttcaatacct cctgaacgtc aaatcgtgtc
    27601 aatattgcca caagatttta ctgtcgatgg gttcgaggga atcaaagatc ctcgtggaat
    27661 gatcggcgta agattagaaa tgtacggtct gttgtttaca ggacctaaaa cgatcatcca
    27721 taacatacgt aaatgcgtgg aaaatgccgg attaatcgtc aacgaaatgg tgattactcc
    27781 tttagcgctg actgaatcaa ttctttctga cggagaaaaa gattttggta cgatcgtcat
    27841 tgatatgggt ggcggccaaa caacaacggc tgttatgcat gataagcaat tgaagtttac
    27901 caatcttgac caagaaggtg gcgaatttgt cactaaagat atctctattg tattaaatac
    27961 gtcatttaac aatgcagaag cgttgaaaat aaactacggg gatgcatacc cagaacggac
    28021 atcaccagat gaagaatttc cagtagatgt gattggtcag tcagaaccag tgaaagtcga
    28081 tgaacgctac ttgtcagaaa ttatttcagc tcgaatggaa cagattttca acaaagcaaa
    28141 agatgcattg gaccaaatcg aagcattaga gttgccaggt ggcgtcgtat tgacaggcgg
    28201 agctgctagt cttcctggtg ttgtggactt ggcacaagaa atcttcggcg taaatgtaaa
    28261 attgtatgtt ccaaatcaca tggggctgag aaacccggta tttacaaatg taataagtat
    28321 cgtggattat tcagcaaact tgagtgaagt gtatcaattg gcaaaaattg ctgttacggg
    28381 tgaaacctca gcagctcgtc aaatggtagt tgaacaagaa acaacaaaca catatgagag
    28441 ctatgaagca cctgaagaaa caatctacga tgagccggaa ccaaaagagt ccggagaaaa
    28501 tgtaaaaaat aaaatcaagg gtttctttac aaatattttt gattaattca tcctgggagg
    28561 aataagatat ggaattctca attgataata atatcaatga cggcgcagta atcaaagtca
    28621 tcggagtcgg tggtggcggt ggaaatgctg taaaccgaat gattgaagaa aacgttaaag
    28681 gtgttgaatt cattacagcc aacacagacg tgcaagcatt aaaaaattca aaagctgaaa
    28741 cagttatcca attaggcccc aaatatactc gtggtttagg tgctggttct cagccagaag
    28801 ttggacaaaa agcggcagaa gaaagtgaac aatccttacg cgaagcttta gacggtgcag
    28861 atatgatttt catcactgca ggaatgggtg gaggaaccgg tacaggtgct gcaccaatcg
    28921 ttgcaggtat cgcgaaagaa ttgggcgcat tgactgttgg tgtcgtgaca cgtccattca
    28981 cttttgaagg accgaaacgt ggccgttttg ctgcagaagg tatcgctcgt ttgaaagaaa
    29041 atgtggatac attattaatt atctcaaata accgtttatt agaagttgta gataaaaaga
    29101 caccgatgct tgaagctttc cgtgaagcag ataatgtttt acgacaaggt gtacaaggta
    29161 tctctgattt gatcacagcg ccaggttacg ttaaccttga ctttgctgac gtgaaaacag
    29221 tgatggaaaa ccaaggtaca gcattgatgg ggatcggtgt ggctagtgga gaagatcgcg
    29281 tagtagaagc aacgaaaaaa gcaatctcct ctccattgct tgaaacatct attgatggag
    29341 ctgaacaagt acttcttaac atcacaggcg gtttggatat gacattgttc gaagcacaag
    29401 atgcttcaga tatcgtagca aatgcagcaa ctggcgatgt aaatatcatt ctaggtacat
    29461 ctatcaatga agaaatgggc gatgaaatcc gtgtgacggt catcgcaaca ggtatcgatg
    29521 aatcaaaaaa ggaacgcaag tctagccgac cagctagaca agcacaaatg caatcacctg
    29581 ctcaaaagac tgtattagat atggatcaag ctaaaccaac ttcttcagaa gaagaaaaca
    29641 gttttggcga ttgggatatc agacgtgaac aaaatgttcg tcctagagtt gatgattcca
    29701 attttgacaa tatcgaaaaa aaagaatttg atacattcaa ccgcgaagaa acaaaatctc
    29761 atggcgatga tgaattaaat acgccaccgt ttttccgtcg taaaaaataa aggagaggaa
    29821 gagcacatga ttgctgacaa cttgcagaaa atcaagcaag aaattcagga ttcgtgtgct
    29881 cttgttcatc gtgatccgaa agaagttaca ttagtagctg taacaaaatc tgttgaatcc
    29941 gctcaagctg aagaattggt tagagctggc gttatgaatt gtgcagaaaa ccgagtagat
    30001 aaattattag aaaagaaaca agatttattt gattttcctg aaataaagtg gcatttaatt
    30061 ggtaatttac agcgcagaaa ggtaaaattg attgtaaatg aaattgatta ctttcatgcg
    30121 ttggacagtt taagattagc agaagaaatc cagaagcggt tagagaaaga attatcctgt
    30181 tttattgaag taaatgtttc tggtgaggaa tcaaaacatg gaatttcacc agatgagctt
    30241 ttaccgtttg tggaatcttt agctgcctgc acaaaaatca aggttgttgg gttgatgact
    30301 atggcgccta aagaagcttc tgatgagcaa atccataaag tgtttggtac gctgaaagaa
    30361 ttgcgtgatc ttgttcaagc aaaaggttat gcccatgcac catgtagtga attaagtatg
    30421 gggatgagtc aagactttca aattgcgatt gaagaaggtg caacatttat ccgtgtagga
    30481 acagcgctat tcaaagacga ataaaggagg aacaaaaatg ccgcttttaa acagaggagc
    30541 aattgctaat tttttcggat tagctgatga ggaagagtac gaataccaag attatcctga
    30601 aacaacaaaa aaggctgtac agccaactaa aaaaaataca acacagaatc aatcaactca
    30661 ttctgtatct gctgcgaata ctcatgaaaa acaaaaaacg gcgacttcac gtcctgtaac
    30721 gcatgaaagt attcagccgg ctgaaaagaa aaaagtaatt gaactacatc aatcacctac
    30781 aaaaactgta gcgaaagaaa gaacagcttc aagaacctct acacaaccta aagcaaatct
    30841 tgctggaaaa atcactgtaa tggaaccaag agcttattct gaagctatgg cgattgctaa
    30901 acgaatcatt gctggagaag caaccttagt gaattttcat ttagtagaag aaaaacaagc
    30961 gagaagaatc gttgattttc taacaggaac agtttatgca ctagatggag atatcaaacg
    31021 tgttggagat gagatttttc tttgtacacc gactgggatg gagattgaca gttcaaccgc
    31081 tcaatctttt gcagatgcga atttgtttga tctgtaagag gaggaactac gatttatact
    31141 attgcactat tacttcattt acttcaacgg gcagcctatt tctatagcat tatcttgatg
    31201 gtatatgcat tgctctcttg gtttccaggc gggtatcaat cagggctagg acgattatta
    31261 gctaagatct gcgaaccgta tatcagtttg ttcgatcgtc tgcctttgag gattggaccc
    31321 ttggatttca caattttagg ggcaatcctg atcttgaact tagccgtaca aggtttagca
    31381 cagatcgtta tatggataac tgtccattta gtttattgat tgaagcaaca aaatctttat
    31441 tctcagaata gataggaggg gaaaattttg gatgcaaatg tataccagca ctttcgggca
    31501 gatgaacgta catttatcga ttcggtaggc gattggattg aacaggttca aggacaatat
    31561 gcaccctatc tgaccgaatt tcttgaccca agacaatcct atattttaga aacactgatt
    31621 cgacaaagca gtgatttgcg tttcatgttt tatggcggat atgaacaggc agaaagaaaa
    31681 agatgtttga ttttccccga ttattacgaa cctgtagagg aagattttga aacagcattg
    31741 tatgaaatcc attatcctag caaatttgcc agcctaagtc atgggaaaat ccttggaact
    31801 ttagtgggaa cggggatcaa acgctcttac tttggcgata tcatctcgga cggtgatcgc
    31861 tggcaagtat ttattgcaaa tgaggtggat cattttgttg ctgcacaagt aacaaagatt
    31921 ggaaaggttg ctgtacgctt ggaaccaatc aaatacacag aaatgattat gccgaaagat
    31981 agctggacac aagaaagagg aacagttagt tccatgcgac tagacagtgt gatctctgag
    32041 atttataata tttccagaca gcggtccaag cagctgatcg aagctggtaa agtaaaagtg
    32101 aactggacag aaaatacaag acctgatttt gtacttgaac tattagatat tatttcagtc
    32161 agaggttatg gcagagtcca gatccaagaa cttgagggga agacgaaaaa agaaaagtac
    32221 agggtactgt tcggtgtatt acgtaaataa aataaaaagg tggtttactc atggctttaa
    32281 ctccattaga tatccaaaat aagacattcc cgacaaaaat gcggggatat aatcaagacg
    32341 aagtagatga tttcttagat ttagttgttc gtgactatga ggaattgact caaagaaatc
    32401 gagaattaga aaaagcagtc aaacattctg aagaaaaact tgagtacttc aatgaattaa
    32461 aagatgcttt gaaccaatca atcatcgtag ctcaagatac ggctgataaa gtaaaaacaa
    32521 gtgcaagcaa ggaatccgaa gtgatcgtta cttctgcaca aaacaaagca gatgagttag
    32581 ttgcgaacgc tgaaaaacgt gcacatcaat taacaactga tgcagaagaa aaagcaagaa
    32641 aaatcttgac agatgcaaca gaaaaagcaa gacagcttgc gacagaaact gaagatctta
    32701 agaaaaaaac acgagtattc catcaacgta tcagcttgat gcttgagtct caattagaac
    32761 aagtgaaaag tccggaatgg gatgaaattt tacaaccatt ctccagctac gtgactgaca
    32821 gccatgaagt gatcaaagaa gttttagcaa aacagcttga caatgaaaat gatactgatg
    32881 taaactcaga cacaggagtc atagaagcac ctatgacggc atttgataca caggctattg
    32941 atatctcgat cgtgcctggt gaaaatgaaa acgagtagaa cagaaaagca ctttgttatt
    33001 cttaaagcga gccgatgaga gtggaagttc ggtaagacac tgcatggtga aagatcctct
    33061 acttgagacc tgcttttccg aaattagagt aagaagcagc ggctgacctc gttattggtc
    33121 acagagagtt tgcactagat agatgcaact aaatttgggt ggtaccacgg catgttcgtc
    33181 ccttgcggct gaacatgctt ttttgtgtcc ggaaaacaaa taaaggagtg tatggttgaa
    33241 tgaaaatgaa agaaaccttg caattaggaa aaacaaaatt ccctatgcgt ggtaatttgc
    33301 caaaccgaga aggcgagtgg caaaaagaat gggaagaaaa tcgaatctac caaaaaagac
    33361 aagagttgaa cgaaggaaaa cctagctttg ttcttcatga tggacctcca tatgccaatg
    33421 gtaatatcca tttaggacat tcattgaata aaatcagtaa agacattatc attcgttcaa
    33481 aatcaatgtc tggctatcgt gcaccatatg ttccaggatg ggatacacat ggattgccga
    33541 ttgaacaagt attggctaat aaaggcgtga aacgtaaaga aatgtccatg gcagaatact
    33601 tggaaaaatg tcgtgaatat gcactttccc aagtagataa gcaacgagca gatttcaaac
    33661 gcctaggagt tgcaggagat tgggaacatc cttatgttac attagatcct tcttatgaag
    33721 ctgcacaagt acgcgtattt ggtaaaatgg ctgaaaaaag ctatatttac aaaggattga
    33781 aaccaattta ctggtctccg tcaagtgagt cttctttagc ggaagctgaa attgaatata
    33841 aagatgtaaa atctccatct atttttgtag ctttcaatgt caaagacggc aaagatattc
    33901 ttgatgaaga tacagctttt gtcatttgga cgacaacacc atggacattg ccagcaaacc
    33961 aaggtattgc tgtaaatcca aaatttacgt atgtattggt ggaagccgat ggccgtaagt
    34021 ttgtcgtagc gaaagatttg ctagaaacag tccaatcaga aatcggttgg gaaaatgtaa
    34081 cagttctaaa agaatttgct ggacaagaaa tggaatatat gactgcaagt catccattct
    34141 atgaacgtga atcacttgtg attttaggcg atcatgttac tttagacgct ggtactggat
    34201 tagtccatac tgctccagga catggggaag atgactatat cgctggtagc aaatataaac
    34261 tatctgtagt gtcacctgta gactcaaaag gattgtttac agaagaagca cctggatttg
    34321 aaggtatctt ttatgacaaa gcaaatccta tgatcactga tctattaaaa gaaaaaggag
    34381 ctttgctgaa gctagatttc tttactcata gttatcctca cgattggcgg acgaaaaagc
    34441 ctgtgatcta tcgggcaact ccacaatggt ttgcatctat cgataaattc cgtcagaata
    34501 ttttggatga agtagaaaaa gtagagtggg ttatcccatg gggtaaaaca cgtttgtata
    34561 atatgatccg tgaccgcggc gattgggtaa tttcccgtca gcgtgcatgg ggagtaccac
    34621 ttccgatttt ctatgctgaa aatggagaag caatcatcac accagaaaca atcgaacatg
    34681 tggcaaaatt atttgctgaa catggatcaa ttatctggtt tgaaaaagaa gcgaaagaac
    34741 ttcttcctga aggatttacc cacccaggtt ctcctaatgg cgaatttaca aaagaaaaag
    34801 atatcatgga tgtctggttt gattctggtt cttctcatga agctgtttta cgtcagcgac
    34861 cagaattatc attcccagca gatatgtatt tagaaggatc agaccaatat cgtggctggt
    34921 tcaactcaag tatcacgact agtgtggcta tcaatggtgt agcaccatac aaatcagtta
    34981 tttctcaagg atttgcttta gatggtgaag gccgtaagat gagtaaatct ttaggaaaca
    35041 tcattgcacc agaaaaagtg atcaaacaat ttggtgcaga tatccttcgc ttatgggtat
    35101 ctagtgtaga ttatgaagca gatgttcgtg tttctatgga tatcttaagt caagtggcag
    35161 aagtatatcg taaaatcaga aatacgatgc gtttcttatt agcgaataca gaagatttcg
    35221 atcctaaaaa agatactgtt tcgtacaatg atttacgttc tgtagacaaa tatatgaccg
    35281 ttcgattgaa ccaagtaatc aaagaaatcc gagaagaagg gtacgacaaa tataacttca
    35341 tgcatattta ccgtacagtt atgaacttct tgacggttga tctatcgtca ttctacctgg
    35401 attttgctaa agatgtagtt tatattgaag cagaagatga ttatcaacgt cgttgcatgc
    35461 aaactgtttt ctatcaaaca gctgtagctt tgacaaaatt attgactcct atcattccgc
    35521 atacagcaga agaaatctgg tcattcctga aagaagaaga ggagtacgtt cagttaagcg
    35581 agtttcctgg ttatgaagag tttgcaaacc aagaagaatt gatggatacc tggactgctt
    35641 tcatggactt ccgtgataat gtcttaaaag cattggaaga agcaagaaac agcaaattga
    35701 ttggtaaatc tttggaagca aaactaactg tttatccaaa acaacaagtt cgtgaaatgt
    35761 taaaagcttt ggatgcagat attgcacaat tattgatcgt ttcaccagac tactttgaag
    35821 ttatggcagc agatgaacaa gtgccagata acgctatggt atttgatgat gttgctatta
    35881 cagtggaaaa agcagacggg gaaacttgcg atcgctgtcg ccaagttcgt aaagatgtag
    35941 gagtagatga aaaacttcct catctatgcg gtcgttgtgc aaaaatcgtt gaagacttct
    36001 atcctgaagc tgtagctgaa ggattcgaag aaaagtaaaa gggaaaaggg ggtgtgacat
    36061 gttctttgtc acaccccctt ttgttatcaa tcgtttaatt ttccacgttc acgataccag
    36121 ttatctggtt gccagatcca ttcgaatccg tctttttcaa gtagttcgaa agctgcttta
    36181 ggtcccattg atccagcttt gtagttggga aaatccggtt gtgtttggtc ccaagctttt
    36241 cgaatgacat ccacgatatg ccaagattga gcgacttctt cccaatgaga gaagttcgtt
    36301 ccatcaccat tcaacgcatc taatagtaat ttttcgtaag cttctgggct attttcaacc
    36361 atttctgcac tatttctaaa ttccaatttg attggttccg tttcaaatcc ttgccctact
    36421 tctttcccat tcaaggataa agaaaatcct tcagttggct gaatatagat cgttagaaca
    36481 ttaggtggaa gtgtcgtatc gtcacatggt tcatcgacag atgttttgaa tacattaaca
    36541 ggaacttgtt tgaatacgat gttgatccga gtcccttttt cagtcaaacg tttgcctgta
    36601 cgtacataga aaggaacacc tgaccaacgg aagttatcga tagtgaattt gcctgcgacg
    36661 aatgtttcag tctctgattg agcatccact ttgtcttctt cgcgatagcc cttgaattgt
    36721 acaccatcca attcaccttg agcatattgc ccgcgaacga agttttctaa cacttcttct
    36781 tcgttataaa tgcggatagc tttcaatgct ttgatctttt ctgtacggat ttctttttcg
    36841 gaaaatgcta ctggcggttc cattgcaagt aatgctacaa cctgtaaaat atgattttgc
    36901 accatgtctt taagtgcgcc actatgatcg tagtagcccc cgcgatcttc tacaccgagg
    36961 ttttcgccaa aagtaatttg gatattgtcg atatagcgat tgttccattg agcctcaaaa
    37021 atattattgg caaaacggat agctgagatg ttttggatca tttcttttcc taaataatga
    37081 tcaatcctga aaatatcttg ttctgggaat acttctctga tttgctggtt caattcaaaa
    37141 gcagactggt aatcagaacc gaacggtttt tctatgatca aacgattgaa gccatttttt
    37201 gtcataatat tttgtgattt caaatgagaa acgatcgttc caaaaaattg aggtgccata
    37261 gccaaataat agacacggtt accgtttaat tgatagtgtc catctaatcg gtcagacaat
    37321 tcttttaatg tctgataatg cgttgaatca tttacatcat gggattgata gtaaaaatgg
    37381 cttgcaaagg tagttgcttc ttcatctgaa ggattcaatg cacggattgt ttctttgaca
    37441 acttcacggt agtgctcatc gctccaggga cggcgagcgg ttccgattac agcaaaatgc
    37501 tcgcctaaat ttccttttct gtaaaggcgg aacaaagacg ggtacaattt acgctgggct
    37561 aggtcacctg taccgccgaa tatcgtaaac aatacatttt tttcattaga catgtggata
    37621 cactccttta tattttatcg acaaaaatcg tgctggccgc cttaaagctg acggggattt
    37681 tctttctatc attttggata gtgatcggtc cttcataagc tgcgatgtca acgatctcat
    37741 attcttcgtt gatattcagg tcaatagtga ctaagtaatc caacaattct ttttcatcaa
    37801 gcactcgtgc gatacgcact tttgtaccga caggatagga ctccaatgtt tgtcggcgtt
    37861 cttcatggac aacttcctct tttttaggaa tcgatcctcc atgaggacaa tgttcaggat
    37921 gattcaaata gttttctaaa tgatctgcaa gatgttccga agtcacatgt tccaatactt
    37981 cagcatcatc atggacttca ttccagctat agtctaaatg ttcaactaaa aaaacttccc
    38041 ataagcgatg tttgcgaatc agactgctag ctttttgcag tccgcttgca gtcaattgta
    38101 caccttgata aggggaatgt tctacaagct cttctttcac aagtttagaa atcatttcac
    38161 tgacagatgc agctgagaca tctagactag atacgatttg tttattgttg actttcgttg
    38221 tatctccacc tagttctaaa atgattttca aataatcttc tcgatttggt gtcatattcg
    38281 atcatccttt catggtaaaa aaccatcatt agtaagtgta acaaaaaaaa cgttaattga
    38341 ctatttttct aaataaaaaa caaaggattt ttagacgttt ttacaacaaa aaacgaaaga
    38401 tgatagagaa gactcattct ttcgtttata aaggatatat atatacattg ggagggatct
    38461 atttttcaga taacaactta tatgaagtgt ctgcagattc gtcataaaga gtttgttcgg
    38521 gataagaaaa gataagataa aaaccatact gatcacgtac gactaaacga tattcatcta
    38581 tttctaccac agatgtgcca agagactgac cgttgatcaa aaacgtgtaa tcagatgtaa
    38641 tctgtaattg ttgtttttgc tggctatcac taaagaacca tgtaccttga tactttgaga
    38701 gtccttctga cttttccgct tgttttttct ttttcaagta aataaaactt gagagaacgg
    38761 taatgagtga accaagaaaa tagatcattt tttttatcac caaatcactc ctttatgaga
    38821 aaataatcgc atagacatat tctttcttct ttatttcatt gtaccgaata aaagctaaaa
    38881 tttctctaag actttcgact ggttttttta ctgtttttct acaaattatg ataggataca
    38941 tagtaggaag aaaggtgaca taatttgaag tatcagcaag tggaaatagc tttttttatt
    39001 gaccgcccga atcggtttat agcacattgt atgaaaaaag acggagaaat aattattgcg
    39061 catgtcaaaa atacaggtag aggaaaagag gtcctgatac caggcgctga agtggctatt
    39121 gtatttgctc ctggacctaa acggaaaacc gcctatgatc tgattgctgt aaaaaagaag
    39181 ggtgactggt ttaatatcga tagtcaattg cctaatcggc tggcaattga tggtatttta
    39241 gacggcacga tccttttacc aggattaact ggtccattta cggtatacaa gcgtgaagta
    39301 acttatcttc actccaaatt tgatatttat ttagagacgg tggtcggaca aaaagcattt
    39361 gttgaagtca aaggtatgac acttgaaaat aaagcgattg gtgcttttcc tgatgcgccc
    39421 acactcagag gattgaaaca tataggagaa ttaacgtatg ccgcacaaga tggttatgcc
    39481 gcttatgtct tgtttattgc tcagttcgaa catcttcatc tggcaacgat ccatgaagaa
    39541 atgcaaccag cactagctga tatggttcga catgcgcagc aaagcggagt tcaaatcctc
    39601 gcctataatt gtcaagtatc ggcagatgag gtaactgtca agcaggccat tccatttgat
    39661 gtagatatcc cttttgaaga tcctatacaa tagaaagaag gtaaaataat gatcaactta
    39721 ggtattatcg gaacaaattg gattactcat caatttgtcc aagcagcttt aagcacaaaa
    39781 aaatatgaat tgacagcggt atattctaga catttggaaa aagcacagga atttggttct
    39841 cattatgaag gggatatcga attcgcaaca gatttgaaga cttttttcaa tattactcat
    39901 atggacacca tttatattgc ttctccgaat agtcttcact ttagtcaagc taagcaagca
    39961 attttggcag gaaaaaatgt gatagttgaa aagccagctt tttcgacgcc aaaagaaatg
    40021 gatgaaatca tccatttggc aaatgaacac aatgtgtatt tttttgaagc agcaagaaat
    40081 atccatgaat caggttttaa aaagattgcc gattacttac cattaaaaga cgagataatc
    40141 ggtgcaaatt tcagctatat gaaatattct tcgcgctatg accaagtatt agatggagaa
    40201 gaaccgaata tcttctcgac tcatttctca ggtggtgcat tgatggattt aggtgtttac
    40261 cttgtatatg cagctgttgc ttggtttgga atgccaaaag aagtccatta tttcccaaga
    40321 aagatttcta ctggtgtaga tggtcttgga tgggggatct tacgttatga gaattttgat
    40381 gtatcgatcc agccaggtaa aatcggtgat tcttatttac cgtcagagat ttattttgac
    40441 tcaggaacgc tagtgatgaa tggagtcaat gcaattgaac aagcacaatt tcatgatcgc
    40501 gcgcataaag aaatcattga tttggcggta acagctgcag aaaatccaat ggcagatgaa
    40561 gcagaggatt ttgccaatgt catggctcat ccgaaagatc cagcttgggg attgttgtat
    40621 gaagagtgga tcgagctagc tagaaatgtg aaccaagtga tttatgattt aagaaaaaat
    40681 ggcggcatca aattcgatgc agataatgag gaagattttt aatgaacgaa tttgtacaag
    40741 tatttcccga aaattggcag aaaaaatatg aggataaagg gtttatctca ccttctctta
    40801 ttcaacgagc agtttttcag ccactaagta ataaacaaag tatagtagcg gtttctccta
    40861 caggttcagg taaaacactg gcttatcttt ggcctctact actaaacgtg gaaccaggtg
    40921 aagcaagtgc gttggtcatt tttgcttctt ctcaagaact agctattcaa gtagcagatg
    40981 ttgcacgtga atggggaaaa gacaaagagt tgaaagtcca atctttggtg ggcggagcca
    41041 acgtcaaacg tcagattgag ggtttgaagg aaaaaccaga aatcttgatt ggtacaccag
    41101 gaagaatatt ggaattgatg aaagcaaaaa aaataaaagc acatcaagtg aaaacaatgg
    41161 tatttgatga agcagaccag ctatttgacg ctgggaacag ccaaatcatt gatcaaattc
    41221 ttcatcaagc tccaacagag tatcagctag cttttttttc agcgacagca gatcgttccc
    41281 ttgaaagcat tgaaaaaatc actgggaaaa cgtttgagac aattgacgtg acagcagagg
    41341 acgattctcg aaaaggactg agacattact ttttacgtgt accgatacga aagaaagatg
    41401 actacttgag acgtctcacg catatagaag attttcatgg tctgattttc tttaatcaac
    41461 tgactgaatt aggcgtaatg gaagaaaaat tgctgtatag aggtgtaccg gtaggaagtc
    41521 tggcctctga tcagaacaag ctactccgaa aagcagcgct agaacaattc aaaaagaaaa
    41581 tggtcagagc acttttgacc acagatgtgg cggctagagg tttagatatt acaggtcttc
    41641 cttatgtagt gaatgcagaa gttccgttaa gtgaagaagc ttatttgcat cgttcgggaa
    41701 gaactggtcg aatgggtaat gaaggaatag taattacact cgtacaagat aataatctaa
    41761 gagatttaaa acggctttta cgtccatcaa atataacact tgaagagatt tttttatacg
    41821 gaggtaagct gcaaactgag cagccaacca aagaagatgc agctcctgca gtaaataaaa
    41881 agtatgcgaa aactttttct ggaaaggagc agaacccaga atataacaaa gaaaaaataa
    41941 gaaaaaaagt taaaaataaa tcaaaaaaag agagaaataa aggagcaagg cgcaaataag
    42001 cgccttttta tgctatgatt atgaaaacgg gaacaaaatt ggttgccaga ggaggggtta
    42061 tgtgaaagaa cgtcaagaag agatcttgca gctattgaca gaaaaccaac aaggattgac
    42121 agcaagtgat gtagctgagc gcttaactat cgatcgaagc aatgcaagcc gatatttaag
    42181 tgaactatac aaggcccatc atattgtaaa aaccgctggc cgaccagtcg tttactcttt
    42241 gccaacggaa aagtcaaaat ctgatgaagt gcatgtcgac tcttctacgc aagtgacttt
    42301 tgaaacactc gttggagaaa atgattcttt aaaagtcagc atacagcagg caaaagctgc
    42361 gattctttat ccaccgcggg ggttgcatac gattattttt ggagaaactg gtacagggaa
    42421 gtcgatgttt gctgaatgta tgtatcattt tgcaatcgat tcagagatgc tttctgcaga
    42481 tgcgccattt gtttctttca attgtgcgga ttatgctcaa aatccgcaac tgctctttgg
    42541 acacatcttt gggatcaaaa aaggggctta cacaggagca gctcaagata gtcccggtct
    42601 aatagccaaa gcagacggcg gtatattgtt tttagatgag atccaccgtt taccgccgga
    42661 agggcaggaa atgctgttta ctttcattga taaaggtatt taccgtccgc ttggagaaag
    42721 tgcacaagta catgaagcat ctgttcagat cattggggcg acgactgaat cttcagaaag
    42781 tttcttatct acgttcaatc gacggattcc tatggcaatc accttgccga atcttgcttc
    42841 acgttcactg gatgagcgtt atgaaatcat ctctcttttt atcaaacaag aagcgaatcg
    42901 tttgaatcaa cgtatcgata tcgaaaaaga agcgattctt gccttcatgc tttatgatgc
    42961 ggaaggaaat atcggtcaag tgaaacgaga cttgaaacta gtctgtgcaa aatctttttt
    43021 acattaccgt actcatcatg agaaaaagct aatcattcga aaagaagaac tttcccttca
    43081 agtacaaaaa ggattactga aaatcaagga aataccggaa cgtctcgacc gattcatgga
    43141 cagcaaaagt cagtatttga catttgaacc aggatttgct gatgttgtct ggtcacaaga
    43201 tccagaacga aacatgcagg tctataacga tattgaggaa aaagtcactt ctctttccga
    43261 aaccggtgtg gagaacattg atctagagac cctcatttca aaagatgtgg atgcttattt
    43321 ccagacatat gtcaaagaat tgactaaaag ttcgattccc aaagatcttt tgccagatga
    43381 aatctggcgg ttaaccaatc aattgtatga tgtggctgaa aaacggttag accgtattta
    43441 taatgaaaaa gctcgttttg cttttgcttt gcatctgcaa agtacattgg atcgtgtgag
    43501 agaaggtcat atgatcgtcc acccagattt gaataacgta cggaaaaatt ttaagaggga
    43561 attccaggta gcaatcgatc tttcaacgat cattgaagaa gaagaacaag ttgagattcc
    43621 ttttgatgaa atcggcttta ttagtatgtt tctttctatc aatctaggag aaagtgagcc
    43681 tgttaaagaa aacaaagtag atgttctcat attgatgcac ggcagacaga ctgcttcaag
    43741 catgttggag atggcacaag aactattagg aacaaaagta gggaaagctt ttaatatgcc
    43801 actggttatg gaagttcaaa caatgtatga agaagtgtta caatatgtca aaaactatca
    43861 agagcatttg acgaatggcc tactcttgtt aacagatatg ggatcattaa acaccttcag
    43921 tgatttgatt tatgaagaga ctggcattcg gacgaaagct atcacgatga caagtaccat
    43981 gattgtgata gaagcgatac ggatggcaag tgttggaaga agcttagaag atatttatca
    44041 aaatatccag ctttcctttg aatcgatcgt acgtgatcag ttcaaagcgg aaaagtctga
    44101 aactttacag cgtaaaaaag ccgtaatcgt gacatgcttt actggtgaag gagtagctgc
    44161 caaattatat cagcgtatta tgccagtgat taatcaaaat aaggtagaac tgatccagat
    44221 gcagttttta gaacgtgaat cattcaaaaa acacatcgat gccttattgg aagaatatga
    44281 gatcaaagca attgcgggaa cagttgatgt tgattatcaa aatatcccat ttttttcagc
    44341 ctatgacgtt tttgatgatg aaaaactaaa tattttaaag cgtatagctg atgatgagat
    44401 cccgacagct aaaattgtcg attcacttgc tggatcatta agcgatgtct tttctattga
    44461 tgaactgatc cgttcattgc aaaagacagt tcagcagatc cagaccgatt tgtcgattat
    44521 cgtggaacct ggagtagata ctggaatcgt tatccattta gccttcatgt tagacggatt
    44581 gatcaaacaa gaaagccatc ggcaatttga gaaactgtct attttctcaa aaatttatcg
    44641 tttggaaatg gatatcgttc gggcaaactt gatggcacta gaacgaaaat atcaggtaaa
    44701 aattccagaa gatgatatcg catttcttac acaaatgttt cttgaaaata aaataaaaaa
    44761 atgaacacac taatcatact gtttacacac taaacatctg tgtgcgcact ataaaaaaga
    44821 gctaaaaagc atgaaaacgc tatttcagct ctttttttta ttggcatgct tcttgcgtta
    44881 tataaaagtg taaaaaaata aaaggagtgt taaaaatggc aaaaaaaaca atcatgttag
    44941 tttgttcagc agggatgagt acgagtttat tggtcacaaa aatgcaaaaa gcagcagaag
    45001 aaaaagggat ggaagccgat atttttgcgg tctctgcctc agatgcagat aataatttag
    45061 aatctaagaa tgtcgatgta ttattattag gtcctcaagt acgtttcatg aaagctcaat
    45121 ttgaacaaaa acttgcgcct aaaggtattc cattagatgt catcaatatg caagactatg
    45181 gcatgatgaa cggagaaaaa gttcttgcac aagcagaaaa tctaatgaaa taaatcaagt
    45241 atgcagttgg gggtataaca acgtggaaga tcaacaaaat ctagaagcca tcatggggtt
    45301 aatcatgttt ggcggtaatg caaagagcga tgcaatggaa gcgattgcgg ctgctaaaat
    45361 cggtgatttt gagttagcgg ataggaaaat cgctgatgca gaagaatcac ttatacaagc
    45421 gcatcatgca caaacagaca tgttgacaca agaagcacaa ggaaatcata tgcaagtgac
    45481 attattgact gttcacagtc aagatcactt aatgacatct attgcgttta ctgatttagc
    45541 aaaagaaatc atcgaacttt atcgtcgcgt atacagcgaa taaatacaac ttcttttttg
    45601 aacggaagaa gaaaaatttt tgaacggatt ttttattttg ttataaggag aactctcttt
    45661 atataaaaaa cttataggag gaagtaaaaa atgaacggac tatcaagttg gatggagaaa
    45721 tacatcctgc cggttgccgc aaaaatcgga gcgcaaaaac atttagttgc tttgcgtgat
    45781 gcttttatcg gcacactgcc cgcaacaatg gcgggatcag tcgctgtaat gatcaatgca
    45841 attattcgtg atttaccgca acagtttaac agtacctatg ctgacagttt agcagcagac
    45901 aaaggaatct ttgccgtatt gaatgtcatc atcggaatca atggttttgt ctggaacggt
    45961 acactagcaa tcgccggatt gatctttgcc ttttcttggg ggtataatct tgcccgagct
    46021 tatggagtaa atgatctagc tggggggatc gttggtttag ctaccttgat tcaaggtatt
    46081 tcctttggtc cagcattatc agcagcatta gatgtgaatg ttccttcaaa tgtcgcagat
    46141 gcaatcaata gttctgagat tggtgcaacg attgcagatg gcacactgtc agttggatta
    46201 tggggttggc taaaactaga tcatttgaat ggaaacgctt attttacagt tatgatcatg
    46261 ggagctattt cagtcattat tttttgtaaa ttgatgcttg ccaacattac gatcaaaatg
    46321 cctgattcag taccaccagc agtatctaaa gcatttgcag ccattttacc agcgacgatc
    46381 gctttatacg tcattgctat tatcaattat atcgtaggtc gtgtagctga tgggcaactg
    46441 atcattgatt tggtgcaaaa atatattgca gaaccattcc taggattatc tcaagggttg
    46501 ggagcagtat tgatcgtcac agtatttgtt caagtattct ggttctttgg tattcatgga
    46561 tcaaatgtat tggcaccagt gctagaggga atctggggac aagcacaact aatcaatatt
    46621 gatattttcc aaaaaggtta taacggaaaa actggtacac cagccgtgtt agatgcaatc
    46681 gaagatggaa aagcttatat gtgggtccgc ggatcgttcg atgcttttgc atggtttggc
    46741 ggatcaggcg gaacgatcgt cttactgata gctatcttga ttttctctaa acgtgcagat
    46801 tatctaacag tagctaaatt atccattggg cctggtatct tcaatatcaa cgaaccagtg
    46861 atgtttggtc tgccaatcgt attgaatgca atcatgttta tcccattctt gattgctcca
    46921 gtagtagcaa cagcaattgg atggacagct acttatcttg gcctagtcgc tccggtatcg
    46981 cagcaagtca catgggtagt accgccgttc ttattgtcat tcttagcaac aggagcggat
    47041 tggcgggcac cgatcgtaac attagtatgt atggtcgtga ctttcttgat ttgggcacca
    47101 tttgtcatct ctgcaaacaa aatggaccct gccgcaggcg aacaacaata agatgaacgt
    47161 gaggagcggg acgctttaag tttcgttcct cataatgaat tttcgaggag gaactgaaat
    47221 gattacaatt gccagtgcaa tgcaacaaga tgaaatcaaa gaattgttag aaggatacaa
    47281 tgaagaagga atgactttta catttaaaga aaaacaagga atcaagctgt tctttgaaac
    47341 aagtgcagaa gatccggaag ttgcggctaa aaaagcaaag gaactaatca aagcacagcc
    47401 ttggggaaca gtcctttatt ttcaatcaac agctgtttag aaaatggttt aaaaagatag
    47461 gatggttgag atgataaaaa acggtttatt tttatgtagt attggttctt tgatcgtgtt
    47521 gtatagtttg aatccacatt cgcaaaggta tgatttgtat agtatggtca caggtctttt
    47581 tctaacagga ttaggaatct atttcttcat gaaggggaaa aaaagagaag aagcaaagga
    47641 gaaaaataac taatggaaat cacgaaaaaa ttaaatattc cagcatcgtt tttttacgat
    47701 aaagttatgg actctgtcct tttcgatgta cgtaaagcga ccggcaaatc agtaactaga
    47761 aaacagctga aaaatttgga gtacgtcaaa caattctcgc aaaataaccg ggctcgcata
    47821 aaaatcgaag aagtcattga aaaccagtct tataagtttc gtacatcgac aacgaagaat
    47881 gaattcgtcg ttcattatca aatcaaacca ttggacgatt cgacctgtga ggttcattac
    47941 acagaaaaaa tggagtctta tggcatgctt caaaagttga atgatatgct tttaggaaca
    48001 atcttgatgt attttaaacg gagacgtttc aaaaaaatgc tagatatgat cgaagcaacg
    48061 tattaaatca atgaaacatg gtactattta gttattgaaa aatgaagtaa gctagaagga
    48121 atttttcata ggaagataga tctttcctgc gaatcctcac tagctttttt gtaggaaggg
    48181 gcagcaaaat gacaaacaaa gtaagagagc taggtgtatc ttcgattgag gaaatgtttg
    48241 atttagccac ttatgcattt aatggggcag atacacctga aaggcgagaa cgttttcgta
    48301 cacttgcgga gaattcttgg aattacggat tttttgatga ggaggatcgg ctaacaagtc
    48361 aagtcatggc gacccctttt ccagtgaatt tttacggaca agagtaccta atggccggca
    48421 ttggctatgt tgcttcttat ccagaagcaa ggggacaagg cgggatcaat cagatcatgg
    48481 aaaagatcct tgaagattgc cgtgatcgta aagtaagctt atcttatctg gcgccattct
    48541 cctatccctt ctatcggcgc tatggctatg aacaatcatt tgataaaatc agttatcaac
    48601 taaacagtcg tgatgtgccg tttatcaaaa aaaaatctgg aaaaataaag cgtatggatt
    48661 ttgaagatgc aaaagctgca atcagaagaa tttatgaaca gatgccggaa aaccaacgag
    48721 ctggtctgaa gcgcgaagac tggtggtata cgtataaatt caagcaaaaa ggcaattacc
    48781 agtttgcttt gcattttgat gataatgagg aagcaacggg atatatcgtt tatcagcttg
    48841 caacgtcttc ctttattatt gcggagtggg gatttttgga tcatgatgct ttttgcagcc
    48901 ttgttcgctt cgtaagttct cacaatggtg cttttgaaac atttgaatat tcatgcggct
    48961 acggcggtaa tgatcaaaat tatctattag aaaatccatt tgcttctgta atgatcacac
    49021 cttatatgat ggcgaggatc gtagatattt ctttgttttt ggaaaattat ccatttaaaa
    49081 agagacaagc tgcatttgcc ctacaaatag aagaagatca ttatgcgaaa tggaatgaag
    49141 gaatcgtgga agtaacaatc gaaaatggaa aaaatcatct ctcaaaagta gaacaaacaa
    49201 aactcccaat cgttcgagga agtatccaac atatcacgca gctattatta gggtatcgta
    49261 aagtggaaga gttggtattc caagaaagaa tacaggtgac aaaagaatat gaagaaacgt
    49321 taagctcaat cttgccacag caacagccaa ttcttaatga ctatttttga taaaaaacgg
    49381 gtgatgacaa tatttttgtc accacccttt tgtttttcat ttggcatttg aaggaaaatg
    49441 ttaaagtaaa tcctcttttt tcgtaaattt gaattttttg ttttcttttg ttttagggtt
    49501 ttcttttttg tggtcttgga ttgcttcttt cgtaatcttt tcccgatttt ttttagatga
    49561 atctaagcgt tctgcgtata ctttttcttt tggcttatca ttcattggaa aggacctccc
    49621 tacattattt cattctacct ctagtttatc atctgttaag gactagtgga aacgttttgc
    49681 ctaacttata agctgatttt tttagcagat aagcttgcaa gtaaaaaaca aacaagctac
    49741 aattgattta ttgaaattgt tcctgtagct cagtaggata gagcaatcgc ctcctaagcg
    49801 ataggtcgct ggttcaattc cagtcaggaa cgtataaata acccctgtat cctttgcggt
    49861 acaggggttt gttttgtatt tgtgccaaaa atgtgccaaa ctagttatca tttttatata
    49921 aactatcgaa cacagtattg attttttctt tatcctgatc ttcaagctct cgaacaatat
    49981 gaagataagt agacattgta gtttctaaac tgctatgtcc taaacgtttc gatacgctaa
    50041 gtatatttac tccttgataa agtaaaatag atgcatgtgt atgccttagt ccatgcaaag
    50101 taaattgctt ttcaagccct aattctttta attttttgcg caaatatttg ctgacggcgt
    50161 ttgatgaaac taatccattt tttaagttga aaaaaacaaa attatgaggg tttttgattt
    50221 caaaattctc gaataattct ttttgattga ttttaaactt ttttaagaga tcaatcgtat
    50281 gtttatcaat ggaaattttc ctatttgaag tttcgttttt tgtttttccc cattcattta
    50341 atttataatt ccatgtttta ttaatagtga tgatttgatc ttcgaaatcg atatcttccc
    50401 atgttaatcc tagaagttca gcaaatcgca ttccagtggc accagcaact aacacgagca
    50461 taggagaaga gtactgcgca gaaaggtttt cttctacgag tttcattaaa gatttaaatt
    50521 gatcataatc taaatattta tcttcttttg gcttcaatga atcttttcct ttgattactg
    50581 cttttctagt tggatcaaac ggaattaatc cttcttctac ggcatctttc aacgacgctc
    50641 taatatggtt attaaactta ataacggtag attttacatg gtctttagca tacttattta
    50701 aaaagcgttg atatcccact ctatctaaat cagaaatcaa taccgctggc atatatttct
    50761 ttatgttcat taacgtatct tcgtattttc tataagtgat aggagatact gttccttctt
    50821 tataaagttg catccaatcc tcaaagtaat ctgataataa tagatttttg cgatcccctt
    50881 taaggccttt gttcaagtta tattctaatt cgttggcggc atcttttgct tctccttttg
    50941 tcttaaatcc tgattttctt atcttcgtgt attttccgtc atcttttttg tatgaaattt
    51001 cgtattgcca actatttcca cgtttgacta atcttgccat aattgaatca gctctctttc
    51061 tctgatacaa taggaactat aaagaagccc attgtttggg ttttattatt ttttgcacat
    51121 cctttttgct tgccggcgca aggatgtgct atttgtcgtt ttaatggtat aattggatgt
    51181 gtattagatc atccaatcag aggtgtttat tatgattaaa gtgattttta aaagaataac
    51241 tgaacttcca gagtttagat tatttgttga ttattggtat gtctggtttt ttattgttgc
    51301 attgctgata ggtctagatg tcatattaga aagaaaactt aagtaagagt tgagttaata
    51361 aattgaattc ctaaatgaga tattttgtag cccatatttt gtttgccgac atcacctaat
    51421 actatggagc taatcgtttt ttctaacaga ccaaaatcag ataatctatt taagctacca
    51481 tctattagct cttgtgaata gccagacatg ctgatatttc cagtgaaatt ttcgtttcca
    51541 cgactcatta agcatgctaa caattgaatc tcaatcgatg ttaattgatt cagtacaaga
    51601 agataatact cctcgttatc ccatgaagcg ttgttaattc gaagtaaaca attcttataa
    51661 agatttttat acatatctat tttattttgt gcctttgatt tttctacctc gtcatttatc
    51721 ccttcgaata ttccaatgag ttggtccttg ttctctaagt tgaaaacatc ttctggaatt
    51781 tgatcgcgaa tgttttctaa tgattcgttt aaatttttgt agaatttctc gatgcgtttg
    51841 aaacgcttct cgtttttaga cccaaaataa agtgactgca caacgccacc aatataagga
    51901 attgctccaa taccgccttc aactattaat tcaagatatt cttttttggt tagtttttca
    51961 tttctattat ccatagttac ctcctatttt gtcatttcct ttacaagcat tgtgactcct
    52021 gatggcactc ttttgtatag gttttattat tgtgcacaat ctaactctta gtggggcgtg
    52081 gttcatttat tttttactta ctttactatt aatcatatcc cattgagcat aggatttttc
    52141 tatgttcgat cctcttgaac taatttctcc tgtaaaagtt actttatcgc cctttgtaaa
    52201 ggtatcagca ttgtttaagt ccttcgcaaa aattacatat gaaactttag gtgttgcaga
    52261 aatatcattc caacttttat catcgtactc tttgtctgct ataatggcta ttctagtagt
    52321 cattgattcg ataacagttc cttcaaaagt atatgtttta ccactaatat atttagtaaa
    52381 agctgtattt tgctcagtag ctggagtaat agaataataa ctatctaaga aagcacccca
    52441 gtcatgatta tttgtctcta aaaattcttc aatttgagtt aggcttttat tgctgctgtt
    52501 agatgtagta gtttgagtat cagatgatga gctttcctgt ttgttattgt catttgcctc
    52561 gtttgatgag gaaagcgaga aacctacggt agtaaaaata atcccgataa taaggagaat
    52621 cataggtgtt ttcttatttg tttttttgat aaatcttaca attaacatga ttaaacctat
    52681 aataaataaa acaataccag taaaaccaaa tataccgtcc attaatagat cctctttctc
    52741 ttttgatatt gaatattata aaccaagcaa ttcttttttc ttaaaatcga attcttcttg
    52801 attaataatc ccttcatcta acaactcttt atacttttta atttcatctg cacttgaaat
    52861 ttgtgtttct ttggaattat tatctaatat agattgttgc ttctctatat atttttttaa
    52921 attttccatt tcattccaat atttttttgt aaacataacg gtgttttcat ctttcgtggc
    52981 cgctaatata cctccgcgac tttcgtttcc gcctagcaag gtaaattgta tataaccatt
    53041 actcatacct ggttttttta attgtacggc tgatatattt ttaaagggga tagttttttc
    53101 tcctttaata ccttgattaa ctaaatttat aaatcctttt ctaataattg aaatagaatc
    53161 atcagttact ttaatcaagg tttttcctgg agattttatt aaaatctctt tttccatttt
    53221 ttcttcctca tttctgtgat atgatttttt ttgtagaagc tcatatatga ggaaagagcc
    53281 cgtgttgcag cacgggcttt tttaatgttt tgctgaaatc ggttttttta ataattcttg
    53341 atgtattcat acatattgcc ttgcgtaaga atattttttc ttaaaatagc attggcagac
    53401 agcataacaa gtgtatctga gcttattctg aatagaataa tactccataa atttttcgag
    53461 attaaactga gattcatcag tcagttcgtt ctcaatatag atatttaata aaattagaat
    53521 agctatttta tctgcttctg tttcaaattt tgagtgaaaa gttgtagaag tatcgtacaa
    53581 aactgaaaat tcaaaatgag aggcgctgaa atgtgcaagt tcatgagata aatgaaaggc
    53641 ttctgcagtt tcaccgtata gattttcatt caaaaaaatg attctgggtt ttggatagta
    53701 gaaaccaggc tctttcatct ccatataaac tactttcaaa ttgtattcgc tcaacatttc
    53761 tttcaatttc aaatacatac aaaccatcac tccaactatt cattttcctc taaagcttta
    53821 gcaattgcaa tcgctttacg cattgtctcc ttagatattt cttttccatc aaaagaaaaa
    53881 acagtatcgt cttctgataa atccacatgt ttaggggttt ctctttcttc tctacctaga
    53941 aggtagtcta cagagacatc gaaatagtca gcaatccgac ttaattcatc tgaattagga
    54001 gtattatttt tccactttgc tagataaccg ttagaatatc caaaattaat ttctaactgc
    54061 cgtatagata tctttttcct cttcgccaag tcttttatta tttcataggt attcatcgat
    54121 aaaacaacct ttctaaatgt ttacaaaaaa agtttagaaa aatacgcaga aataatttga
    54181 cta
//
LOCUS       DAFKHN010000009        53991 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFKHN010000009 DAFKHN010000000
VERSION     DAFKHN010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.009"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(70..1491)
                     /locus_tag="LY912_000546"
     CDS             complement(70..1491)
                     /locus_tag="LY912_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6954265.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1734..3611)
                     /gene="tdc"
                     /locus_tag="LY912_000547"
     CDS             complement(1734..3611)
                     /gene="tdc"
                     /locus_tag="LY912_000547"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBM6954266.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3902..5158)
                     /locus_tag="LY912_000548"
     CDS             complement(3902..5158)
                     /locus_tag="LY912_000548"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBM6954267.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVANRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5270..5475)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5738..7039
                     /locus_tag="LY912_000549"
     CDS             5738..7039
                     /locus_tag="LY912_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBM6954268.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7108..7707)
                     /locus_tag="LY912_000550"
     CDS             complement(7108..7707)
                     /locus_tag="LY912_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6954269.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7961..8842
                     /locus_tag="LY912_000551"
     CDS             7961..8842
                     /locus_tag="LY912_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954270.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8855..10465
                     /locus_tag="LY912_000552"
     CDS             8855..10465
                     /locus_tag="LY912_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBM6954271.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10542..11201)
                     /locus_tag="LY912_000553"
     CDS             complement(10542..11201)
                     /locus_tag="LY912_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBM6954272.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11484..12149)
                     /locus_tag="LY912_000554"
     CDS             complement(11484..12149)
                     /locus_tag="LY912_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBM6954273.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12296..12901)
                     /gene="dhaL"
                     /locus_tag="LY912_000555"
     CDS             complement(12296..12901)
                     /gene="dhaL"
                     /locus_tag="LY912_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBM6954274.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12929..13939)
                     /gene="dhaK"
                     /locus_tag="LY912_000556"
     CDS             complement(12929..13939)
                     /gene="dhaK"
                     /locus_tag="LY912_000556"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBM6954275.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(13914..14360)
                     /gene="dhaM"
                     /locus_tag="LY912_000557"
     CDS             complement(13914..14360)
                     /gene="dhaM"
                     /locus_tag="LY912_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBM6954276.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14463..14783
                     /locus_tag="LY912_000558"
     CDS             14463..14783
                     /locus_tag="LY912_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBM6954277.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14895..15764)
                     /locus_tag="LY912_000559"
     CDS             complement(14895..15764)
                     /locus_tag="LY912_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBM6954278.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(15860..17164)
                     /locus_tag="LY912_000560"
     CDS             complement(15860..17164)
                     /locus_tag="LY912_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBM6954279.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17161..17670)
                     /locus_tag="LY912_000561"
     CDS             complement(17161..17670)
                     /locus_tag="LY912_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954280.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17845..19980)
                     /locus_tag="LY912_000562"
     CDS             complement(17845..19980)
                     /locus_tag="LY912_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBM6954281.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20063..21718)
                     /locus_tag="LY912_000563"
     CDS             complement(20063..21718)
                     /locus_tag="LY912_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBM6954282.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21720..22034)
                     /locus_tag="LY912_000564"
     CDS             complement(21720..22034)
                     /locus_tag="LY912_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBM6954283.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22204..22464
                     /locus_tag="LY912_000565"
     CDS             22204..22464
                     /locus_tag="LY912_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBM6954284.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDRNPEEQAAKLEQAIKMIIKK"
     gene            22478..22792
                     /locus_tag="LY912_000566"
     CDS             22478..22792
                     /locus_tag="LY912_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBM6954285.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(23522..24076)
                     /locus_tag="LY912_000567"
     CDS             complement(23522..24076)
                     /locus_tag="LY912_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBM6954286.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(24202..26131)
                     /locus_tag="LY912_000568"
                     /pseudo
     CDS             complement(24202..26131)
                     /locus_tag="LY912_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(26437..27153)
                     /locus_tag="LY912_000569"
     CDS             complement(26437..27153)
                     /locus_tag="LY912_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBM6954287.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(27154..28977)
                     /gene="glpO"
                     /locus_tag="LY912_000570"
     CDS             complement(27154..28977)
                     /gene="glpO"
                     /locus_tag="LY912_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBM6954288.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(28991..30487)
                     /gene="glpK"
                     /locus_tag="LY912_000571"
     CDS             complement(28991..30487)
                     /gene="glpK"
                     /locus_tag="LY912_000571"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBM6954289.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(30623..32083)
                     /locus_tag="LY912_000572"
     CDS             complement(30623..32083)
                     /locus_tag="LY912_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6954290.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(32073..33368)
                     /locus_tag="LY912_000573"
     CDS             complement(32073..33368)
                     /locus_tag="LY912_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBM6954291.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(33700..34377)
                     /locus_tag="LY912_000574"
     CDS             complement(33700..34377)
                     /locus_tag="LY912_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBM6954292.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(34407..35498)
                     /locus_tag="LY912_000575"
     CDS             complement(34407..35498)
                     /locus_tag="LY912_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBM6954293.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(35599..36033)
                     /locus_tag="LY912_000576"
     CDS             complement(35599..36033)
                     /locus_tag="LY912_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBM6954294.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(36617..38074)
                     /gene="ascB"
                     /locus_tag="LY912_000577"
     CDS             complement(36617..38074)
                     /gene="ascB"
                     /locus_tag="LY912_000577"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBM6954295.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(38071..39966)
                     /locus_tag="LY912_000578"
     CDS             complement(38071..39966)
                     /locus_tag="LY912_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBM6954296.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(40024..41799)
                     /locus_tag="LY912_000579"
     CDS             complement(40024..41799)
                     /locus_tag="LY912_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBM6954297.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(41849..43345)
                     /locus_tag="LY912_000580"
     CDS             complement(41849..43345)
                     /locus_tag="LY912_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBM6954298.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(43539..45161)
                     /locus_tag="LY912_000581"
     CDS             complement(43539..45161)
                     /locus_tag="LY912_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBM6954299.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(45489..46802)
                     /locus_tag="LY912_000582"
     CDS             complement(45489..46802)
                     /locus_tag="LY912_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBM6954300.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(47047..47271)
                     /locus_tag="LY912_000583"
     CDS             complement(47047..47271)
                     /locus_tag="LY912_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954301.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(47291..47713)
                     /locus_tag="LY912_000584"
     CDS             complement(47291..47713)
                     /locus_tag="LY912_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBM6954302.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(47855..48565)
                     /locus_tag="LY912_000585"
     CDS             complement(47855..48565)
                     /locus_tag="LY912_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954303.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(48583..49080)
                     /locus_tag="LY912_000586"
     CDS             complement(48583..49080)
                     /locus_tag="LY912_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6954304.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(49117..49569)
                     /locus_tag="LY912_000587"
     CDS             complement(49117..49569)
                     /locus_tag="LY912_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBM6954305.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(49704..50309)
                     /locus_tag="LY912_000588"
     CDS             complement(49704..50309)
                     /locus_tag="LY912_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBM6954306.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(50759..51379)
                     /locus_tag="LY912_000589"
     CDS             complement(50759..51379)
                     /locus_tag="LY912_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBM6954307.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(51381..52250)
                     /locus_tag="LY912_000590"
     CDS             complement(51381..52250)
                     /locus_tag="LY912_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBM6954308.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(52273..52680)
                     /locus_tag="LY912_000591"
     CDS             complement(52273..52680)
                     /locus_tag="LY912_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBM6954309.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(52699..53988)
                     /locus_tag="LY912_000592"
     CDS             complement(52699..53988)
                     /locus_tag="LY912_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6954310.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        15296 a        11441 c         9266 g        17988 t
ORIGIN      
        1 aaaaactatt cacttggcag gacctcctac taaatcagcg acaaaacgtc ggctgaaaga
       61 cttatttttt tatttttctt ctaaactttt ttctacctca atcccccaag aatctttctt
      121 gaagtgattg atgatcaatg gaataacgaa catgaccact gtgatagctg ctactaataa
      181 tgcatcactc aatgtcgctg tacctaatgt agcaaatacg acaacgatga tagagaagat
      241 cagcatgcag ctgactaccc aagctaatcc gtttccgttt ttaccaattc ggtaaggacg
      301 ttcgaattct ggatgtttct tacgcatttt aagcaatgaa acagcaatca aaatgtacac
      361 gatacaataa ataacagttg tagcatttgt aagtgtcaag aatacagcac ttacgtcatc
      421 cattacacca taaagcaaag caaataatga aataacgatt gattgtgtta gaacgacatt
      481 tctagatacg ccgtatttgt tttctttatg gaatccgaat tttggtggaa ggaatccttc
      541 acgagctact tggatgattg tttttgatgg tccagtaacc caagctgata attgtaaaag
      601 cacaccaata aataccatga agctgaagat atttccgatc acttctggta agcctaggat
      661 ttgacagtca atcaagatag gctgcgtgat atttgctaat tccatttttc catctggtac
      721 gacatttgct acaagcatcg cattgatgac attcaataaa actaatccga tcaaagcgat
      781 aaatacgcct tttgtataat tttttgttgc gtctttcaaa cgaggcatgt aaacagaact
      841 catttcgatc ccaacaaaaa taaatgtgat accagctaag tatttcaatg aatcaatatg
      901 ttccaagtca gggaaagctt ttgaccatga aaagtcacct agatagccgt ttgagactag
      961 tccgactttg aaggctgcca aaacacctaa aacgaacatg atgactactg ggatatatac
     1021 ccctagccat acaccgatgt tcccgccgac ttttgccata tcgaatttca agttcaagat
     1081 cgtgatgatc cagtagataa ctaaaataca acctaaaacg aaccagtgat tattgccaag
     1141 ttctacatta ccaaatgtgt ttcctaacaa tggtcctaaa gtagaagcga ccattaccat
     1201 acctgggaac atttgcaccc ataatagcca tgcaacgaca aatccccatt tgctgcccag
     1261 tgctgttttt acccataact gaggaccgcc ttcttgagga agcatcgtgg aaagctcacc
     1321 ggaaaccatt gatatcggac cggcaaaaaa caaaactgca aaaattgaat aaaaaatcaa
     1381 tgtccaaccg actgcggcta acgtaggaat actccgaacc gttgcacaca gtgccattgt
     1441 cagaccgata aaggtcccaa gacccatttt acttacttca gatttactca ccgttgacac
     1501 tctccttgat tttttggata aaataacggt gtctttgaag tagtttcagc aataaacgaa
     1561 acaattcagc gaatatttga ggggattctt tgagtttatt gcttgaaggg tttcttcaaa
     1621 gacaacctca aaacaaaggg atcgaagagc ttaggtctcc ccttgctctt cagatccaaa
     1681 catgcgtcag aaacagttag tattcaagct gttttctaac atgattacct tgcttatttt
     1741 gcttcgcttg ccaataattg gtctgcgtag attttttcca atttttcttg aagagctgct
     1801 ttgatttttt cagcatattc ttcaaagtgt tcttctttgt tcatgtatgg tgtcattacg
     1861 ctggcacgca atacagttac ttttccggca cggttccatt cttcatctga gaatcctagt
     1921 tggttcacaa attgtaatgg gctgttgcca tagtctggga tagcaaagtc agtatgtgaa
     1981 gttaagaact cattaccgta aatgcttcct ttcacgtatg aagaataatc atatacgtca
     2041 tggttcaatt tattcattgc aactaagtca tcgttgcctt tttctttgaa tacatagtct
     2101 accatattga aatctggata agttaatgga tgaacttcga tttctttgtc tcctacttta
     2161 aatgacaagt cattcaagaa gttgtagaaa cgatgtgcac cttcgattga tgcacccatt
     2221 aatttaccat atcctgtgac attcaaaggt aagacatggt gtgctgccca aacgctggct
     2281 gctgttgccc ctgcttttga accttccaag atataagccc caagtaatgc tgggatatct
     2341 gcgccttttt caaatacata tgtcgcaaag taagagataa cgtctctcat gcggatatct
     2401 ttgatgacga taccaccggc agaatatgga acatagccca ttttatgtgg gtcaatcgtt
     2461 acagattctg cttcttcgat tgctttatat gcactgtgta cttcttctaa gatataatct
     2521 ttgttttctg taaagacatt gtatttgtaa tgaacatctt ttaaatcttc aaatggaatg
     2581 aagttgttgt cttcgtctaa gaaaatcgca cggccgtatc cgccataagc agcatctacg
     2641 tgtaagtaga agtaaatacc gtctttttct aatacgcgac gcaatgcaac gattttatcg
     2701 ataccgtcga ttgctccttc ttctgttgat cctacaacac cgactacacc taggattggt
     2761 gttttttcag ctgctagacc acgaacgatt ttttcaagtt cgttgatgtc catgcgatag
     2821 ttgtggtcaa ctggcactgg aatcacttgg tctaaaccga taccgatgat gtcggcagct
     2881 tttagccatg aatagtgttt agtttgtgga accaaccatt ttcctaattt ttctaaatgt
     2941 tttccgctac gtgctgagtg agctttgatt tcgtcgattt tttctgggac gctgtctaac
     3001 agattcatga tttcttctgt tgacaagttc attaattccc aatcgctttt tccagcaact
     3061 agttcaggtg tcacttcttt cattgcaagc ggcaatgatt tgatgttgcg ggcataccaa
     3121 agtccttcta agtttgctaa agaaccatca gcaacgatgt ggccccagcc atctttatag
     3181 ctcattaatt ttgcaaattc cattcctact tcttcttcca tttggcttgt tgcaggagaa
     3241 gattcatagg caacgttatt accattccat agcatagcaa aattgtacgc tagtaaagat
     3301 ggcatcaatg tttcagagtt catatgaccc cagtaacgtc cggcattatg ccaaggaacg
     3361 gaatgggtac gcatccgcgc tgaaatttct gatagaacat cctttgtttt attcacagtg
     3421 tgttcaaaac tagcactgct tttttcttct ggcgtaataa taggcatgtc ttgaggcatg
     3481 tagttttgac gccagcctaa atgttcatcc accaattcat tcaacaaagc tttatagatt
     3541 tggccgttct cagctttgtc cccaatgaat agggcattta ggtttagatc tttcgacaat
     3601 gattcactca tagtgaaacc ctcctaaaaa aatatttaaa ttttgtcgag ccctacatta
     3661 cacctgttct tctattctgt aaactaagtt ttggcctgat ttttaatcat attttaatat
     3721 gtatcaatta tccgaattgt tcacactttt gaaataatta aaaaaaacga gggaatttac
     3781 aaatgtaaac tccctcgcaa agattgtatt aacgacaacc agcgttctat tttaggatgg
     3841 gtttcaaaat tggaatgttg taatagtatt tccctttttc aaggtaaaaa cttactaaat
     3901 tctaatcaat tactttggcc aaaaagtaat ttttcttacc ttttcgaata accacaaact
     3961 taccatcgaa ttcatcggat ggatttatga caaaatttaa atcggtaacg cggtcaccgt
     4021 taatacttat agctccgttt gaaacatctt cacgtgcttg acgtttagat ggttcaattt
     4081 ttgtggaaac aagcagttcc acgatatttt caggtgtgct tgaaatttca acgttcggca
     4141 ttttaccgaa tccttgcgcg atttcttccg catttagttc tttaatattt ccagagaaca
     4201 atgcttgcgt tattttttgc gcttctttca agtcttcttc actatgcaca aatcttgtaa
     4261 cttcttctgc caaacggcgt tgtgcttcac gtttctcagg ttctgtctct acttttttcg
     4321 ctaagtcttc gatttcttct tgagacaaga aagtaaagaa tttcaagtat ttcactacat
     4381 cgcgatcatc ttgattcaac cagaattggt agaactcaaa tggtgaagtt ttcttcggat
     4441 caagccaaac ggcaccgcct gcagtttttc cgaatttcgt tccgtcagcc ttcagcatca
     4501 atgggatcgt taaaccgaac gcttctgctt ctggtccttc taattttcgg attaggtcta
     4561 atccagctgt gatatttccc cattggtctg ctccaccgat ttgcaattgc acatcgtatg
     4621 ttttatgcag atgcaaaaag tcgatagatt gcaggatttg gtaagtaaac tctgtaaatg
     4681 agattcctac ttccaaacgg ttggcaacga tatcttttgc taacatcgtg ttgatgttga
     4741 agtttttacc gtagtctctc aaaaattcaa gtaaagagat ttttgacaac cagtcgtagt
     4801 tgttcacaaa tgtgatattt gcatctttac caaacaattt tctcatttga ttggaaagtg
     4861 cgtccacgtt atgttgcact tgttccatcg tttgcaacac acgttctgtt ttgcggccgc
     4921 ttgggtcgcc gatcgttcct gttccgccgc caatcagaat atatggatga tggcctgcca
     4981 attggaatct tttcatcatc ataaatggaa tcaaatgtcc gatatgcatc gaatcaccag
     5041 ttggatcaac gccgcaataa agtgaaatgc tcttttcttc aacgagctcg cgaagtcttt
     5101 cttcgtttgt ttgctgatta atggcgtcgc gccaagttaa ttcatcaata atattcattt
     5161 tactgacctc cgtgtagttt ttttatgaaa gcaggaacct gctagcatat gtaattaatt
     5221 atttcttcag gataggatag gaaataaaaa aagtcccttg gcatataagc caagggacga
     5281 aatctcgcgg taccacccaa tttgtatgtc tagatatcca acatacctct cgaacattta
     5341 acgctgtcgc gtggcaatca ctgccaaaga ctcctgaaat gtaattcgct ttaaagcatg
     5401 tactggtttg cagcgaccac cagctttctg aaacattggc tttaacaact acttcgtttc
     5461 gatcttcgtc ttgttattat taatatgtgt ctatcataga gcgcaacttt ttctttgtca
     5521 acagaaaaag gatatttttt ttaaattcct cattttttct tttttgaatc cgctctaatt
     5581 ccgaacattt tattttcaat tattgttaaa agaaataact ttttctgtat tttttctgca
     5641 atttatcgag aagtcacttt actttgcctc ttattctttc ttcgttacaa taaggaatgg
     5701 gacaagtaaa aaaatgaaaa agcaagggac gaggtatatg gaaaaaaagc aaaaaattat
     5761 tttaggagcc acttctgctt taactatcgt tattttaatt ctaagtttgt tttttgtcat
     5821 ccgatcatct acaaaaaaag aaccaatcat tcctgaaaaa aaaataacag aaaaagcaaa
     5881 agaaccgaca gatgataagc aacaactagt tactcaagca aaaaatctgg ctcaaagcta
     5941 cgattatgac caagcgattg cgttattgga aaaagatagt aagaacggat ctactgaaac
     6001 acaacagctt cttcaaacac taaaaaagga gaaagaacaa ctgatcgact ggtctgatcc
     6061 tactcagatc tctcatgtct ttttccacag cttgatcgtg gacccgcaaa aagccttcca
     6121 ctctcaacag gcacaaggat acaaagatta tatggtgact gttgaagaat tcaaccgttc
     6181 gatcgaacaa ctttatcaaa atgattttgt tttagttaat ttgaatgatt tgatccaaaa
     6241 agacgaacaa ggaaatcttt cctttaacgg gcttgcgcta cctgaaggaa aaaaaccatt
     6301 ggttctttca caagatgatg tcagctatta tgaatatatg gataattccg gttttcctag
     6361 ccgattggtc gtatcaaata acaatgaaat caaaaatgtc tataaagaga aagataaaga
     6421 agaaatcggt gactttgaca tggttcctct gatcgatgcc tttgtcaaga aacatcctga
     6481 tttttcttat cgaggcgcaa aaggtacctt ggccctgaca ggttacaacg gagttttagg
     6541 ttatcgaaca tcaaaatctc aatatggaga caatgaaaaa acaaaaaaag agattaaaga
     6601 agctaaaaaa gtggcggaac agttgaagaa agacggctgg agctttgctt cccatacatg
     6661 gggtcacttg aatatgactc aagcttcact agaagatgta aaaaaagaca atgaattgtg
     6721 gcagcaagaa gttgcaccta tcctaggaaa aacaaatatt ctgatttatc catttggtgc
     6781 agacatcagc gactggcagc cttattcagc agaaaatcaa aaatttgctt acttgaagag
     6841 tcaaggtttc gatattttct gtaatgtcga tgcttctaca ccagcttggg gacaattagg
     6901 tacggatttc tatcgaaatg ctcggatcaa tatcgatggc attcgttttc aatctgattt
     6961 agacggaaaa aatcctattc ttgatccatt catcaatgtc catgatgtct atgacaaaga
     7021 agcacgcgaa tctgcttgat tttacgtcat ttatgaacca aaaaagccga actgacattt
     7081 tatcgtcagt ttcggctttt ttatgcttta tttcttcttc ggtgcgattc ccttgatcag
     7141 gacttctgtc cattctgctg tatatggaag cagttttgcg tatatctccg gcttagaaat
     7201 tccttctacc attgcttgaa aatagaggat caagaactca tccgaatatt tcaaatccac
     7261 ttttccttct ttccgccctc gatggaaaag atcaagcatg atactgaaac tttcttgcgt
     7321 atacgcatcc atcgcgtcag aaaattcttt tttttctttt tttgtatagt atgtcatcaa
     7381 atcgatataa aattgtttgt tcactcgatt gagataacgg attttgtttt cactcatggc
     7441 aatcagtgtt tcttcaaatg gaagattttc cgcaatcaac gctttcgctt cttgccctaa
     7501 atcattcata aatgcaaaaa atacttcata aatcagccct tccttgctgc caaaatattt
     7561 aaaaatcgtc gctttactta cctgagcgtt ctcagctacc ttatccattg tcactccagc
     7621 ggttcctatg tctgtgttca tcaagtcaaa agctgcttgt aaaatctctt tctttttctc
     7681 ttgtgctctc ttttcaaaac cgttcatttg tagagcctcc cgtaatttta aacttttata
     7741 atatatatag ttcaaattta ttctgaggtt tattataact atctattgag aaagtatcaa
     7801 gctagcaatt ccttgtttat gaattcattg acagaaattt ataaaaagaa tattatgtac
     7861 taaaataata aaaaaagttt tataaaaagg tataaaacct ttttattaaa ctatttaatc
     7921 ttgtttagta tatattttta gaaaaaggag tggggttttt atggcagaaa tcgtcaaagt
     7981 cacacatttg aaaaagagct ttggtcgttt cgaagcttta aaagatgtct ctttcaccgt
     8041 acattcaggt gaagtcgttg gatttatcgg accaaatggt tctggaaaat ccacgacgat
     8101 tcggacactt ttagggatta taaaaaaaga cggcggaacg gcaacgattt ttgggcaaga
     8161 tgtatgggaa gatagtttat ctatccatga acgtctttct tatgttccag gcgatatctc
     8221 tttgtgggga aatttgactg gaggagcgat catcgatctc ttcatgaagc ttcatggaaa
     8281 agggagtgct caaaaaaaag atgaactgat tcaacgtttc tctcttgatc ctaagaaaaa
     8341 agcaaaaaac tattcaaaag gaaatcgcca aaaagtgggc ttgattgctg ctttggctgt
     8401 tgattcggat ctctatttat ttgatgagcc tacttctggt ttagatcctt tgatggaaac
     8461 gattttccaa gaagaagttg aaaaattgaa agaacagggc aaatccatcc tactttcttc
     8521 tcatattctc agtgaagtcg agcgactagc ggataaagtc gtgatcatac gcgaaggaac
     8581 actcgatgaa gaaggaacac tcgatgaatt gcgtcatttg actcgttcga ccatcactat
     8641 agaaacagaa gcagagaata gtcacttagc acaattgaac ggtgtccatg actttgtgca
     8701 aaaaggtcac ctcgctcaat ttgctgctga taacgaagct ttcgatgtga ttttagctga
     8761 agcgtccaaa ttaggtgtga aaaaatttga atctattcca ccgactcttg aggatttatt
     8821 catgagacat tatgaaggat gaggaggaag cgaaatgact gataaatttt cacgctggtc
     8881 cacccttttt tctcaaaacc ttagccgtga ctggaaaaag atcctgatat ggctagtcgg
     8941 tgtcactgct ttttctggtg gttttgtccc tgcgtttgaa gaattgactt ccggacaagg
     9001 attagctgga ttatacgaaa ccttgcaaaa cccggcaatg attgcaatgg tcggaccaac
     9061 tccagcttcg aatgctgctg agtatacttt aggagcgatg tatgcaaatg aaatgttgct
     9121 tttttgcagt ttgtttgctg ctgtgatctc tgttttacac gtggtgagcc aaacgagaaa
     9181 aaaagaagaa cttggtctga ttgaacttat tcgttccttt cgagtcggac gtcaagcaaa
     9241 ctctttagct gtcatcgctg aaagtattct gatcaatttg cttttagcaa tatcgatcag
     9301 ctgtacgatg atttttttcc aagcggattc gatcactgca gaaggtgctt ggctttttgg
     9361 gctatctgta ggtagtatgg ggattttggg gagtgccgtt gcactgtttg ctgcacaact
     9421 gatgccaagt tcagccagtt cgaatggtct gtctttagcg tttttaggtg gactttacct
     9481 tctacgagca ataacagatg tagctgattc ctccctttcg atgtggaatc ctttaggctg
     9541 gtcttatttg acctatccat ttacaactaa caactggatt cctttgcttt atttgttttt
     9601 gttcagtcta atcttgataa tcagttcatt tgttttagag gaacatcgag atttgaacac
     9661 cggctatatc cccgaacgtg aaggaaaacc gtatgctaaa cgttctcttt tatccttgcg
     9721 tggtttatta ttctatctaa ataaagggat gacaatcagt tggcttatca cttttggttt
     9781 gatgggggcg gcatacggct ctatctacgg gaatatgcaa cagtttttag aaagtaacga
     9841 cttaatgaaa cagatgttta tccaatctgg cgtctcaatt gaaaaaaact ttacaagcac
     9901 gatcatggta gtcttgattt gtctagctgc tattttacca attgctagca tcaatcgttt
     9961 atttacagaa gaaacccacg gacgtatgaa tcagctgttc gcaacaaaaa tttctaggaa
    10021 ccaactttat tggaccaata tgttactagc tattctattt gctatattgg caatcctgat
    10081 tagttctggt gcactagggc tttctgcttt ggcttcgatg aaggatgcga aagacatgga
    10141 tctattgatg tttcttaaag ccgggttcaa tttcctgcct gccgttttag tgtttatcgg
    10201 aattagtggc tttctattcg gatggcttcc tcgaatcggt aaacttgctt atatctactt
    10261 agcttactcc tttgcactca attactttgg cggaattttg gatttaccag aatggttttc
    10321 caaaacagct gtccctagct gggttccacg gatgccaaac gattcttttg atctttccgt
    10381 gttccttacg ttatcatgta tcagccttgc actgttcgtc cttggttcta ttggttatag
    10441 gcgaagagac ttactagaag gataataaaa aagcatgtac aatttcatgc tagcctccaa
    10501 atctgggtca aaaatccaac atttggaggt cattttttta tttacaagtc ttctaactgc
    10561 tctttatcaa tgatccagac ttctcgattc tttcttttta cataaccatt ctcctctaat
    10621 aatttaaatt ttctagataa agtttcgggg gtcgtaccga taaatgcagc aagttctttc
    10681 attttcattg gcaggaaaaa gtgatccttc cctgtcgctt tagctaagtc aagcagatag
    10741 acagcgactc gttcttctac tttttccatc atcaaaaaag ttgtctgctg ctgtactttt
    10801 gttaatttct caacgttgat tgctaaaagt ttcagactaa gggcgggata atgcagtaag
    10861 agttccgaga aatctttttg tctcaatatg caaatttccg ttttttctag tgcttcgcca
    10921 aataaagact catttggaac gcctagcaac tggctctctc cctcatatcc gcccggctct
    10981 attactcgta aaagctgttc ctttccgcta gcagataatt gatacacttt catactgccg
    11041 gaggccacga tcactaattg aggttctcca ttcggcgcaa gaatctgttc tcctttttcc
    11101 acatagtgat gtttgacaag tgcgtgtact ttttcttgat cttgctgtac taagtgattg
    11161 aacaaaggaa caaatgaaac acataaatga tcatgactca taatctctcc tccttctaaa
    11221 cagctatttc taataaagaa acataacttc ccttattcca actgataatt ttcttttatc
    11281 atagcataaa cgtcaagcga accagatacc agcaaataga gtggatttct ttttgtccct
    11341 tgctttattt tccttctttt gagaccttaa gtaattgatt cctatcaatt ttttaaatat
    11401 ttactttttg aataatcaaa aacaaacctt cactcgcaag ccgagagtaa ggtttgtttt
    11461 tcgcattgct tatttcgtgt tgtctattga aatttttccg cacctagctt ttgatatagt
    11521 ggtgctagtt cttgtaaggt ttcagcggtt atttgctcaa cgtgttcgat ttcttgcgga
    11581 tagaagaata gtttacccat ttgaaaggtt cggtctctca tcgctttttt caactcttct
    11641 tgtttctttg tatcggacaa atagtcagac aaagctaagt ggtcgtcaag ttcatgttct
    11701 ggttgcggcc atatgtaata atccttgata tcgactgttt tgctccactc tttcagtatc
    11761 gcaagcaact ggttatacgc tgcaatgcta ccatatcgtt cttcgctttt ataatgttgg
    11821 tacatcaaat agatttggta ttgtttttga ttcaacaaaa ctgctagaca ggcattctcg
    11881 tcttgacgag attcgcttcg gtacgcgctc caaaaatgac tgcgtaaatt ccagccattc
    11941 gtccagcttt cgattttagg tttgctcatg ccgtacatat caggcaaaag tgcagctgtc
    12001 tggagctgaa tctctttcca tttttgccag tgttctttat attctttctt gatttgttca
    12061 atcttatctg ttggatggct ctctttgagc tgtttgaatg cgtagattgg tcgatcaaac
    12121 aactgataat ctgattttcc aagttccatt gtttcgcctc tttccgttat cttttgtatt
    12181 ctacctgaat tttgcgatat ggacaaatag aggttgtgaa aaagctgttc tgcatcaagt
    12241 cataagaaca gccaaacaaa aaactgcgat gagcatcacc gcagttttat tgaacttaag
    12301 gttgattgat cacatctaaa agcgttgaaa ataaaatggc actagaagca gctcctgggt
    12361 cgatatgtcc gattgcacgc tctcctagat aggaagctcg tcctttttta gctaccaaga
    12421 ctttggtgtg ttcttttgcc tggtcaatga tttcttttgt taaattccct gccttcaatg
    12481 cctctgtgac tggcagccaa acatctaaca tcgttttatc gtcagcttct gcctttcctc
    12541 ggctttgaat acccgctgtt ccctgctcga tcacttcgcc taatttttct tgagaatcaa
    12601 tagaatcgac ctcttttgtc gctttcatca tgttcatgaa tgcagatccg tataacggac
    12661 cagaagcccc accgactttc gatatcatcg ccatagagaa tactttgaat gtatcgctga
    12721 ttgtttcagg atgatcggct tgaaaagctt cttcataagc tgaaacccct cttcccatgt
    12781 tatttccatg gtctccatcg ccaatcgggg tatctagatc actgagatat tgtttgttct
    12841 gattgattgc ctctgcaaat tgcgtgagcc attcttggat ttcttgaacg gttagtttca
    12901 tattatcacc cttttatctt gagatttttt accatgaaat cgtctgtaca ttgctttcta
    12961 aagaatcttt ccattgtgtc tccgtcaagt cgatcagtgt tagagaaaga ccttgcatat
    13021 ctagtgaggt cataaaatta ccgacttttc ggaaaactac attgacgcct ctttcttcca
    13081 acagagctaa aacatcattc atgaacacga actgttccat caaaggcgtc ccgcccattc
    13141 cgttgactag tacacctgct tcttttggta aattcgagta atcatctaaa atcttagtaa
    13201 caagttcctt tgccagtact ttagaaggct gcatcttttc tcgacgatag cctggctcac
    13261 cgtggatacc aacaccatac tcgatctcat cttctcctag ttcgaatcct ggtttcccta
    13321 cttctggtac agttgctgct cgaagcgcta gaccgatcgt cttagttgcc tgtacgacct
    13381 tttctcccag ttctttcaac tcagctaggg aagcaccgtt tcttgctgca tcgcccacga
    13441 ttttgtgtac aaggacagta cctgcaactc cgcgttttcc agcagtatac gtactatttt
    13501 caacggcgat atcatcatct acgatcacac tttctacttc aatatcgtcc atagcagcta
    13561 attcctttgc catatcgaag ttcaatgcat cccctgtata attcttaacg atcagcaaaa
    13621 ctccttttcc actatcggct tccttaatag ccgtctgaat ctgatctgga gttggagaag
    13681 taaacacatc accaagcacc gctgcactta acatcccttc ccctacaaac ccggcatggg
    13741 atggttcatg tccgcttcct ccaccagaaa ccaaaccaac ttgttccgct ttctgattct
    13801 tggctacaac acgggaagat tctacacgat gaacaagttc tggatagctt tttactaatc
    13861 cttccagcat ttcttcgaca atattgcttg gatcattcat gatttttttc aatttattcc
    13921 catcctttct ttccggcatt ttgtgcttct gttaagattt gctgagtatc atctgttata
    13981 ccggcagtga tggctgctgc aaaagctcct tccactaaag gcgcatccac cagatgataa
    14041 cgttgctgct gctcttcttc caacatgtct tttgccagtt ccgagttcaa taccgcgcta
    14101 ccgatatccg caaaaacaaa ataactagct gcatcgcttg attcattgac tgcttctacg
    14161 attttcatcg ggtctgatcc gatctcgcca tttattccgc cgagagaaaa aatttgcacc
    14221 tcttcggatt tttgcatctg ctcaatcatt tctttaatac catctgttac tttttgacta
    14281 tgagaaataa gcaaaatact ttttttcaca agaatcttcc tttcttttac atagttgcta
    14341 acgattggtt tcgctttcat taatgaacaa ttcaagtata taataaattt ctaattttgg
    14401 gaaaatatgt gtagtgcttc ttgaagtttg ttatacttta attaaaagag aggagtgatc
    14461 gaatgattac aacaacaacg aacagtgtag agggaaaagc cgtagtagct tataaaggga
    14521 tcgtttttgg tgaggtcatt actgggatcc atgcatttaa agacttggag gcggggttgc
    14581 gaaatatctt tggcggccgc tcaaaaagct atgaaaacga actaatgggt gcaagagaag
    14641 aagcacttgc cgaaatggcc gaacgtgcaa aagcattagg agctgatgcg atcattggcg
    14701 taaaaatgga ctatgaagta ttaggcagcg acaatggcat gctgatggtc acatgtagtg
    14761 gaacagctgt ctccacgaga taagtagggg acatctgttt taataactaa agagagatgg
    14821 gacatgtagt ggcactcaag aattagattt ttcagtctaa cttcgaggta ctctaccttc
    14881 ccatcctctc ttttttattt ctttttgcgg atgattccgt aagctgctgc gactaacaca
    14941 cccgcccctg ctaaggaata actgacagaa gctgtttttt catttgtttt tggcaaagtc
    15001 tgacttgttg atttggatgg ctctgtcgtt tgctgaactg tttctgtcgt gcttccagag
    15061 gtcactgatt tttctcctgc cgaatgcaaa atatctttta ttcgttggaa actagctgct
    15121 aagtcagctt tttttgcttc aaaatcatta gcaactgttt gtgcttcgct gatctttccg
    15181 tggattgctt gactggccgc tgtgatatcc gcttgagttt gacttagctt tccagaagct
    15241 gtttgagcaa cctgatttaa ttgctgattg aattcttttg cttgttggat cttcccgtca
    15301 agatctgttt ggacagcttc cgcttttgct ttcgcttcgg caagcttttt ctcaagttgt
    15361 gcacggtcat ttcccacttt atttttaaga tcagctaaat cttgatcgat tgctgcttgg
    15421 tcttctttca atttgttttt tgcagcttct aatgcttctt cgagttcttt tcttttattt
    15481 tccaagtctt gcaaatgatc gatttggtca gaagaggtag aactatttat tgatgtatct
    15541 tctgaagatg aaatcgtttc tcctgaatta tctgtcggta cattggaagt catttctgtt
    15601 tccgaggcac cgttttcagc accagaagag cttatggttg ttgaaggttc tgtttgagca
    15661 ggttcagaag tttccgcaaa agctgtctgt cccaataaga aaatactgga aacagcaatt
    15721 ggccagatta acggcttcat tctttttttc atcacttttc ccatccttac tactttttaa
    15781 ctaatttctt attataagca aaaatgtttg gaagaaccat aaacacaaca ggctgtttgt
    15841 ctaaaaaacg gtgcatcttt tatttttttg tacgttccgg gcttttccat gtcccgcttc
    15901 cataacctaa aatcgttttg actgctggaa tgaaagtcgt cacgatcgtt atcgcgttca
    15961 ctatccagaa caaaagcata tatagtggtg cgaaaagaag gtatttcaat tttcttcgtc
    16021 gatcatctac aatcagcgaa gctagcaact ggaaaaatcc tgcgaccatt tcaaagcaga
    16081 tgaacacaaa actgaatgta aaagtaatat aaatctgttc gtagtttcct tgatatacat
    16141 aatgcccgat taatccagca aaaagaacta cggaaataca aaagaatatt gaccagacaa
    16201 tactcaatgt ttgatcaatg aagatgatcg ttcttccaat atgtttaaaa ggatggagca
    16261 tcactttttt gaaattcgtc agccagactt ctgttccacc ttttgcccaa cgttttctgt
    16321 gtcgatatag catcttcaac gtcacaggta cttccatgaa aaagataatc tcaggagcaa
    16381 aaacagataa ccagtcattt aactgatgat cccaagcaat actgatgtct tctgtcgctc
    16441 gatcttgtct gaatccgccc acatcgatca aggcttcttt tcgatacatc gtatttgctc
    16501 cactgtacgc ataaagacca ccgaaaacag ctgactgtgt tcgtttaatg atgcccacga
    16561 tacttgagaa ttcaaccgtt tgagattttg caatcaattt ggtacgattt tggacatcca
    16621 tatttgcagt gaccgcagca atatgtcttg caccagggcg aatgaaataa ttcacatacc
    16681 taatcagtgc atctggctcc ggtaccgtgt ctgcatcatt gcttaaaatc aatttccctt
    16741 ttgcaaaggc aagtccgata ttaaacgcgt gggcttttcc tttatttttt tcgatccgaa
    16801 ccacacgaag attagcgtat tttttcatca gtctagctaa tatttctggt gtttggtccg
    16861 ttgaaccatc gtctgtcact aatacctcat agttgtgata attcaatttc gtcatcaaat
    16921 actcgattgt atattcgatc acaatttctt cattatgggc tggcaccatg atcgtgatga
    16981 acggttcgac actcaaggga acatctaccc attctttttg cttatgtttg tataaaaaca
    17041 cataacacca gacaccaata aaccatacaa atccgcctaa aatcggataa gaaacgagaa
    17101 aaaaatacat aatagacaaa caagtatcta agaataaatt acctgtatgg gtgattgaga
    17161 tcatttcagt tccaccccat tttctttata caaatctgca atgaatgtcg tatctagatt
    17221 tttctcttcg gagacagaat aaaaacggac cgtttctctc tcttcttttg ttccaaaacg
    17281 ttccgtatac acttcttcaa gtaattcttg tctttttttc aatttttcat cttcatattc
    17341 aaaagattta tttacttttt tgtatagatt tcgattgttc cacctagtca atacaaatga
    17401 ggtaatcagg aaactgaaaa aaatcaatac aaaaaagccg attaagaaat acagcatttt
    17461 cttttctgat aaaaaagcgt acaaggaaaa atccttggct ctttctggtc tcgttaatgg
    17521 gaaaaagacc catataaaag gaagaacaac gatcatccat cctaaaagag ccactaacgt
    17581 ttgccaaatc tttaaccagt aattaccttt tgaaaaatac ttatctttca ccaaaattga
    17641 tgcaacttct tctcttgtta cttttttcat atcctcacct cacgtttttt tgttacgacg
    17701 taggagttta ccatacattt catttctttt cacataaagt gttcctaaat ttttcctaag
    17761 aaaaagaaca aaacatttct catcagcaaa tgaaaaatat tttgttcttt ttatcagttg
    17821 ttctttttat tttttatctc ttaattatgt tgctctttcc aatacgacaa tgcttttcat
    17881 tcctctagat atcgccgtgt acatttgtct gcgtcttctt tgctcatctc catcgttttc
    17941 aaatggatat aagattacat gatcaaattc cagtcctttt gctagactca aaggaatgat
    18001 ttggcagttt tctaatccat atgaattttt tttaatcgat tcttgtagcg tttgggtttc
    18061 ctcttctgtt tgggtgataa ctgccgcttt ttctcctttt agagaaacca aaatctcagc
    18121 tagtattttc aacaattctt cagaggatcg aaaagagcgg tattcgggtt cttttccttg
    18181 cggtcggatc gatacgatgt cgatcttctc ttgatccaca gcataggttt tgaaaagctc
    18241 tgtgattgct ccgctagaac ggtaactatt tctaagatca taccgatgga tcggcagatg
    18301 gtagtcgtcg aaacaacgca taatatcagc aaaagtagtg gaagaattaa agattgcctg
    18361 attctcgtca cctactaaag taaagtgagt ttttggaaat aattcgatca atagacctaa
    18421 ttgtgccagg gtataatctt gtacttcatc aatcaataga tagcgaaatg ctggtacatt
    18481 taccttttca acaagtaaat gacgaatagc taatataatg actgcttcat caacagtacg
    18541 tgtgggttgc caagcataag ctgagccata tcgtttttca taaattcttt caaacaactg
    18601 atgctcatcc acccatgcca tttcttcgat ttgtctggtt atttttcgat attttttttg
    18661 taaaagtttc cttgcataag ctacaatact ttgttccgaa tcatcagaaa tcaatttacc
    18721 gaataattcc aactgcctat cttctgtcaa cgagagtacc tgattctgca cagcaggact
    18781 ttttgcttgt ttcaaaagat gattcttcca ttcgctcatc agtgcctttt tcgttgcttg
    18841 aagcctatcg atcaatttag gatgagcagg aactttctca tatatttttt cgatcgtttt
    18901 tttagaaagg actgtttttc catttttagt aagtccacgg ataaaattcg gatgatctaa
    18961 aaacaaagga tctgattgtt ttagattatc gataaacttt ttgctacgca aacgttctgt
    19021 ctgctccgat acattttctc ccgtgatacg tttgaaataa gcctcttcac cttctatttc
    19081 ctctgctgaa agctgtgaaa ccagctgtat gatggttaga ttcagtggat ttctttcacc
    19141 taatgatggt aggacattcg aaatatagtc gataaaccga tgattaggtg atagaatcag
    19201 caagtcatcg gatgtcatcg tatctcgata taaatagagc agatacgcaa tacgctgcat
    19261 gatagcagag gttttaccac ttcctgctac gccatttacc aagatatttt gacttttcac
    19321 atcccgaatg attgtgtttt gttccgattg gatcgtagca gtgatagcct tcatttcatt
    19381 ggtctcatct tggcctaaga cttctaataa tacgtcatct tgaatagcta cagacgtatc
    19441 aaaaaacttg accaaacgat ctctttccaa aagaaattgt cgtctttctt taataaccgt
    19501 atcgatttta ttttgacgaa ccgtataaga agatggacca atcatgttat tgtaaaaaag
    19561 ttcggcaatt ggtgaacgcc aatcataaac aagattttca tctgcatcat ctgtgaaatt
    19621 tgctgtaccg atataaaagg attcttttgg ctcattatcc agaaagtcta caacgacttt
    19681 tccaaagtag ggacttttca ataaacgttc gatctttgct agctgatttt ctgcgttttt
    19741 ctgtttgata ttcatctgat cgatttctct atttttcatt tcaatcatcg aaaaagtatc
    19801 caggttatct aagtaactgt caaaattcaa tcgaagctcg ccagccattt ctttcaacga
    19861 ctggtttcct tctatttttg ccgtatccat cgattcccgc agttcgtttt ttttatcaat
    19921 tagcttttga tacacgttct tcagatatgc ttcttctaac tgtttttgtg tgttgaccat
    19981 acacattctc ctcttttttt aaagtggtgg aaccgattag tttacctctt ttaagagtcg
    20041 aatgcaagct ttttaacgag tatcatttgt taggatatat cagttcttca ggtcggacag
    20101 tttgatataa agaaaatgca ccatcaaggt tttttacgtg gtagccagac tgcttcaaga
    20161 ttctttccgc tagatagcta cgtaatccgc tatgacagct gacgatatat tcttgttggc
    20221 tgtctaattc atttaatcgg tcccgaagtt cattcaaagg gatatgtttg gcttccttga
    20281 atttgccctt ttccaattct tctgctgttc gcacatctaa taaaattttt ccttttgcta
    20341 gttctgtcgg caattcatgc cattgtacgg tttcactaag cccttctgca atgttcattg
    20401 ctgcatatcc tagcatgttt actggatctt tggctgagcc aaatggcggt gcatacgtca
    20461 attctaattc cggtaaatcg aagatcgtca aatgcccttt gattgctgtt gctaaaatat
    20521 cgatccgttt atccacacct tttgccccaa caccttgtgc accataaatc tcgccagtct
    20581 ctggatggaa gatcaacttc agtaaaatat ctgttgcttc tggataatag cttgcatgat
    20641 cttttcctga tacatgaatg acttcaaaag acagttcgtt ttctttggct gttctttcac
    20701 ttaaaccggt ggatgcggca gtcattccaa acgttcgtat aattgctgtt ccaataccgc
    20761 cttgatttct tcgagaaatt ccggaaatcg tgtccgcaac ttgtctacct tgacgattgg
    20821 ctggtgaagc aagagaaata agtgcatctt ttccagtgat ttgctgtttt acaacgatag
    20881 catcccccac cgcataaata tcaggaatat tcgtttgata acgttcgtct actaggatac
    20941 ccccgcgtat gcctaattcg attccagcgg tcactgctag ctggttatca ggacgaacac
    21001 caatggataa aataactaaa tcagcaggga tggtacgccc atcatccagt cgcaatcgtt
    21061 tcccgtggtc ttcaaatcca gcgacagcat gagaagtaat cacttctact ccttgatgag
    21121 acaattcttt ttctataaaa gctgccattt cttcatccag tgttggaaga atatgtggtg
    21181 cttgttcgat caccatgact tctaaacctc ttctttttag gttttctgcc atttccaatc
    21241 cgatgaatcc tgcaccaacg atcacggcac gctttggctg tttttctaat gcatgcatca
    21301 ctttatcgat atctggtaca tttctaatag aaaaaacatt gtcggcttct gttatccctg
    21361 gaatcgatgg aacaactggt tttgcaccag gagataaaac caatgcatcg tactgttcaa
    21421 tgtgtttttg accctcatgt acgacttcta ccgttttgtt ttcgggaaag atggctgtca
    21481 cttcatgatt tggacgcaca tctaaacaaa aacgagcgga taatgattct ggcgtttgga
    21541 caagaagatt ttcccgttca ctgatttctc ccgaaagata ataaggcaag ccgcaatttg
    21601 caaaagaaac atacggtcct ttttcaaaaa caacgatttc tgcatcttcc attaatcggc
    21661 gaagccgtgt agcagcagac attccacctg ctacacctcc gacaataacg attttcatct
    21721 tatttccctc ctactgttcg atcaaaccat tgattcatgc caccacgtac attcactaca
    21781 tcataaccag atttctttaa ttctttagct gcttgtttac tcctcatccc tgattgacaa
    21841 atcacataga cggtcttttc tttgtctcca tcatatctgt ttatactttg taatggaaca
    21901 tttttagctc cttttatatg cccgccccgg tattctgcag gtgttctaac atcaagtaac
    21961 gctggatttt ccaaaagctt ttcctttaat tctgggactg ttatcgattt tattgattga
    22021 aatagcaaat tcattttctg cacctcattt acatttttat aaatacctca tggggtatat
    22081 taaacaggag ctttattaat atgtcaacca gaatgactct tcattttttt cactactttt
    22141 tatatttgca taaaataccg ataaggggta ttatctaatt ataaaaatag aggagaatgt
    22201 gttatggaga ttgataataa aaatatcctg aaccgtttga aacgtacaga gggacaaatt
    22261 cgtggtatcc aaaaaatgat cgaagacgaa aaagaatgta tggatgtcat cactcaatta
    22321 agcgctgttc gttctagtat tgatcgcgta atgggcatga tcgttgcaga taatctgaaa
    22381 aattgctttg agaaacctga tcgtaatcca gaagaacaag cggctaaact agaacaagcg
    22441 atcaagatga ttattaaaaa gtaaaggaat gatttcaatg aaagtcgttt tccatattga
    22501 tgaattagaa aaatggtcag aaacagggaa aaacgtaaaa aacctgataa aagcttctcc
    22561 agaaacgacg attgtcgtat ctgtaaatgg catcgcgatt accggttatc tagactctgc
    22621 caatgcagaa ttcttagatt tgcaaggagt cgtttttcac gcttgcgcca atgctatgcg
    22681 tgctaatcat atttcagaaa gttctttacc tgaacaagta atcgttgtac cagcaggtgt
    22741 ccttgattta gttgaactgc aatcccaagg ttatgcttat atcaagcctt agtcagtaga
    22801 ggttgcgaca gaagtgatca gcttcaagaa atttcggctt atttttcgaa gaagctactt
    22861 ctggaaaacc gtgaatcaaa ggttgtgaaa acgctgtcct gcatcaagta ataagaacag
    22921 ccaaacaaaa atagcttctc atatttttcg tttggttggg cttattaccg cagatgcaag
    22981 cttttgaaca ccgtttaagg aagaggttgt gaaatcagcg gtttgaccta agtattagag
    23041 aaaaaaacgg gaaaatagct cctcatattt tgccgttttt tgagctaata ccgaaggtca
    23101 gctgattgaa caccgtttaa ggaagagatt gtgaaaaagt cgcttagttt cgagtattaa
    23161 gaaaaatttt gtgaaaatgg atttctacat ttttgcataa atttggctta ataccgagaa
    23221 actggctttt gaataccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat
    23281 tagagaaaca aacggaaaaa tagctgctca tattttgccg ttttttgagc taataccgaa
    23341 ggtcagctga ttgaacaccg tttaccaaga ggttgtgagc ctaccattta actccgaatc
    23401 acaagaaata atttcaaaaa caacttctcc tgtttttggt tcggttggct tattatcgag
    23461 aagtagctac tgggagtcta tttatcaaaa aaaggaatgc gacataggtc acaccccttt
    23521 tttattttct ttgaaacatc tttcggtact cgacagcata caagacaaaa gattgtaaaa
    23581 gaccgtaagt gatgacggca aaaatgactc tcacccacag cgttggtaat tctgggaaaa
    23641 gcagcaaaag gatcatgcca acatagatga cagcagtcgc tactttgcca taccacttcg
    23701 ctccacttaa tttgatattt ttagatagcc cgattaatcc agctacaaac ataaagcctt
    23761 cttttatcaa gaatagacca aacaacagcc aaagccacgg tcgataccat gccatagaca
    23821 aaatcagaaa aagttgtgtc aatttatctg caaacggatc aagcaccttc cctaagtctg
    23881 ttacctgatt atatctccga gcaatgaccc cgtctagata atcagacaaa cctgagacaa
    23941 caatgaccgc tcctgctata taaaatgact gtctcagcac aaaataaaga taaatcggca
    24001 gcaaaaaaat acggaatatc gataaaagat tcggaatcgt ttgtatttct ttacgccagt
    24061 ctgtgcttaa tttcatttta tcgccctacc tcctcagcac tcttttcttt ttattttagc
    24121 ttacacgggg aataaaacca atgatttcac tgtttttatt tttctttaca gacactgata
    24181 ttatgagcta atttgagata atcacttgct gttttcatcg tttactcttc tttcttcctg
    24241 tcgtttgcgc atttctttta ctagtacttt atgagctttt tttgatcctc gctctaggtc
    24301 acgctgccgt ttacgtgttt tataatcgat aaacagactg tctaaatcgt aacctgtcgg
    24361 gtacagatct tctgctgaac gcaccagacg aacacgctga cgaggcacgt ggattatttt
    24421 tttgtctaaa tatacatcaa tcgtatcttc acctatatct tcataaacta acgcttcttt
    24481 ttggtattca ttgacaaata tccgatcacc ttttgcaaag agctgacgtt cttttttatt
    24541 ctccttccta tttgtaactg ctgtcttagg aagaaattct tttttctgtg tccgataggc
    24601 tttttccgcc aagtaacgct ctgcttgatg gatcaatttc atcgacatat ccattttatg
    24661 agcaatccac aaagcttggc tttctcctgt ttcttccaac ccgcaactga tatttaggac
    24721 gaagtgcttc ccgatcgaaa gccatagcag ccggcacaaa atcttcatga tctccggcga
    24781 atttcttgat ttctccataa tgggtcgtgg caatgatcaa tgccccttgc tcatacatag
    24841 attccatgat tgcgatcgct agtgcagccc cttcatttgg ctctgttcca ctgccaatct
    24901 catctaaaag taccaacgta ttccttttta tctttttcaa aatagcagcg atgttttgca
    24961 tatgaccaga aaatgtactc aacgcatttt ctaaattttg gtggtcaccg acatcgacga
    25021 aaatctcatc aaagacagca agctctgtcc cttcttttgc cggaacttgc ataccgaaca
    25081 tcgccatcaa agtcaataaa ccgactgtct tcaacacgac tgttttgcct ccggcatttg
    25141 ctccggtgat aatcaagcct cgatagtctt taccgatttc aacatccaat ggtaccgcat
    25201 gctcaggtaa aaatggatgt ctgccttgct tgataatgat atgttccgat ttattgattc
    25261 taggtgtgct tccattgatt tctcggctaa attttgcccg agcaaagatg atatctaaca
    25321 ccgtgatcgt ttcgatcaat aaatcgatca cttcttcgtt ttctgcgata gcaccagtca
    25381 atgccgccag gacttgatat tcttcactga tttcttcagc ttttaacaac tgatagtgtt
    25441 cattcaattt agaaatcaca gttggttcaa taaaaaccgt cgttctttta tttgattcat
    25501 cgataatcgt tccatctatt ttatttttat agctggcttt gataggaatc gtatagtatt
    25561 cgcctttttg aacaatcatt gcttcttgga tcatttcttt gtttttcgga tgacgcaaga
    25621 atttcagtaa ttttgactgg atttcttttt cgattagttg taattgtttg cgtactttac
    25681 gcaaattacg tgacgcgtcg tcactgactt tattattttt tattttctgg tcaatcaact
    25741 cttctacatt tatcaaatca ggaagatgtt tgctataagc aaacaacaag ggtgtctggt
    25801 attgattctt atcaaaaaac tttgtgatca tccgactgct tctaagaaaa tccgcatatt
    25861 cgatcaaatc ggttggctgc agaatcaacc cttttttgac ttgttctgtc agtgcatcga
    25921 tcctcggcaa ccccataaat ggaacatgct gactgctttc taagatcaag cgtgcttctc
    25981 ttgtttcttc ttgacgatcc aagacagttt gtaggtttgt cgagaccgtc atatcgctga
    26041 ttcgtttttt gctatagttt ccaattgctc ttgcttggat ttcctttttg atccgatcaa
    26101 attgtaattg actaatcatt tcgttgtcca tattctctcc ttttcttgaa gagatacctg
    26161 tcccaaaata aataagggcc tagagataaa taaaaggata gaacacagct taaaaaagtc
    26221 atgtcctatc cttattagaa tacaaagata ttgttttcct gacaggtacc gtttcataag
    26281 cacaccaaat aaactttgtt tattggctat tcgacttact gattagatac cagctacact
    26341 cacaaaacat accccattct tctaggtctt atttattttc cacttaacta tagcaagaca
    26401 cattttggtt gtcaaacttt agtatgtttt atagatttac accattaatg aatagacacc
    26461 taccgcgata attgctccga tcattggacc tgcgattggt acccatgaat atgcccaatc
    26521 tgaagttcct ttattagcta ttggcaatac cgcatgtgct aatcgaggac caaagtcccg
    26581 agcagggttg attgcatatc ctgttggccc tcctaatgaa agaccgatgg ctaagatcaa
    26641 tccacctaca gcgaatacgt tcgttccagg tgcaaattcg ttttgtccaa aagctagcaa
    26701 cccaagaact aatacaaatg taccaattaa ttctgtgatc acatttgctg gataattccg
    26761 tatagcagga cctgttgcaa acgttcctaa aatcgcgctt tcatctttcg ttgcattcca
    26821 atgtggcaaa taagaaagcc aaacaagaat ggcccctgca aaagctccta aaacttgcgc
    26881 aatgatgaaa ggaacgacaa gattccaact aattgcccct gtcatcgcca tagctagaga
    26941 gactgcagga ttcaaatgag ctgggcccat gaatccagaa atatagacag ccattgttac
    27001 agcgagtccc caaccaaatg cgatgacaat ccagccagaa gcctgtgctt tacttttgtt
    27061 taaattcaca gccgcacaca caccatctcc aagcaaaact aggatcagtg tcccaataaa
    27121 ctcccccatg atttgagtca tatcactgtt catttatttc tcccccttta gttcccgcag
    27181 atctgattct gcaatcaatg cttctaaacg tttagtctgt tgcgccttct cctcttctgt
    27241 ccattcaaaa tatccagcaa ttgcatcgat cacaggttgc ttgatctcat caagctgatc
    27301 tcgttcaaac aacagatgat ttgtacgacg aatgagataa tcgcctgggg ccaaaaccat
    27361 ttcttcttct aaaccataac gtaaccgagc tgactcagcg agactcaaac caggataagg
    27421 tgccatttct tttgctaatt caaagatacg tcgggcatta gtcccgtaaa aatcagcgat
    27481 ataagtagca tcttcttcct ctaaaccggc tgctactcct tcttttgcta attctgtcac
    27541 tgtttcttct aatttagttg gatcgaagtt tccacctgaa atctgatatt ttttagagtc
    27601 gatttctttc gtctctattc cgtattcttc ttttaataat tggcgtatca atcgcaaagc
    27661 tccttctgcc atcttacggt aatcggtgat tttcccacca gataaagtca gcaaaccatc
    27721 tggttctctt tctaaagaac tacctctgga aatcgtagaa ggtgcttttt catcacggct
    27781 gttttccaaa tggttcaaca cgtcttctac ttcagcacga gaaactttgt tttccttata
    27841 ttcacttact gtatcgacaa ctttattgaa gctcttgtct gaaatcgatc cattatctcc
    27901 accattgtaa tcagaaccag aattaccaat caacagtgga cgaagtcctg cccagcttgc
    27961 ttcgatatca ttcaatgtga tatttgcttc tggatagcga tgattgatca catccaatag
    28021 ataatctaca tcttcttgtg tgactttcgg atccgtaaaa tctccttggt aatccgtatc
    28081 tgtcgtacca aagtaagtct tgttttctct tggaatagca aaaaccatcc gcccatcttg
    28141 ctttcctgta tcgaagtatg tgggttgcgg tacaggcagt tttttcgcat ctacaactaa
    28201 atggatccct ttagttggac gcattttagg agagactgga cgcgtaaaat tcaagtttcg
    28261 tactttatct acccaaggac cactcgtatt gatcactaat tttgctttga tttcgatcac
    28321 ttcatctgtc agcaggtcac gagctttgac gccaacgatt tgatcgccat catataaaaa
    28381 gccaaccgct ttcattttac ttactagata agccccatct tcggcagcct ttttgatatt
    28441 atcaatcact aaacgggcat cattgttgcg gaaatctaga tagacacccg cgccttttag
    28501 cccttctttt ttcaaaaacg gttctctttc caatacttct tctggtgtca gcgtataatt
    28561 ctcatatttg gttcctgtca catttgccag tttgtcataa aggtccattg ctactttgac
    28621 cgagaacata ttgaaggttg ttgctccttc gccctcatag attggcaaaa gcattggatc
    28681 tggttttggg atgtgtgggg caatactttg tacgactgca cgttcaccaa ctgtgtcagc
    28741 tactacttcc acatcaaatg tcttcagata acgaataccg ccatgaacaa gtttggtcga
    28801 gcgagaggaa gtcccttctg caaaatcctg catttcgatc aatcctgttt tgattcctga
    28861 tgctgctgac tggactgcca caccggcacc agtgattccg ccaccgatga tcaacagatc
    28921 caattcttct tgctgcattt tttgaatgct atcttgtctt gtcttgtttg aaaacatatg
    28981 gatttcctcc ttattcaaat gcttgggtag cttttactgc ttttttccaa ccgttgtaaa
    29041 gtttttctcg gcgctcttcc tccatttgaa cttcaaatag cttgccagct tcataaaatt
    29101 cgcggatctc gtctgtatct ttccaataac cgacagctaa tcctgctaaa aatgctgccc
    29161 ctagcgccgt tgtttccaag ttttctgctc gttggatcgg tacattcaag atatctgttt
    29221 ggaattgcat cagatattca ttgtttgctg caccgccatc tactttcaat acaggaatct
    29281 tgattccagt gtcatcttgc atcgtatcga tgatatctct cacttgataa gcaatcgact
    29341 gtaaagtagc tttaatgata tcttcttttg tcgtaccacg tgtcaagcca aacatagccc
    29401 ctcgtgctgc ctgatcccaa taaggagcac ctagcccaac gaatgcagga acaacataaa
    29461 cctcatcttc gcttgtagag cgtttcgctg cgtcttctga atcgctagct ttttgcaaca
    29521 tttgaagtcc atctctcagc cattgaatcg aagaaccagc cacaaaaata cttccttcta
    29581 aagcatagta aacctttcca tttatgccgt aaccaattgt cgtcaataaa ttatttttgg
    29641 ataattgcgg tttttcaccg gtattcatga caataaatga acctgtacca taagtattct
    29701 tgaccatgcc tggttcgaat gccatttgtc cgaataatgc ggcttgctgg tctcctgcca
    29761 tccctgaaat tggtgcttcg cttccataaa aatgataacc ttgcgtataa ccataaactt
    29821 ctgagttaga agtgactttt ggtaacatca ctcgaggaat atttagtaaa tctaaaatct
    29881 cctgatccca atctagctga tggatattga acaacatcgt ccgactggca ttcgagtaat
    29941 cagtaacatg tgcttgtcca tcggtcagtt tccatactaa ccaagaatcg atcgttccaa
    30001 acatcaattc gcctttttca gctcgttctt gcgcgccttc tacatgatca agaatccagc
    30061 gtatcttcgt tgctgagaaa taggcatcga tcactaaccc tgttttttcg tggaaaaatt
    30121 cttgatagcc ttcatttttt aagttatctg caattccagc tgactgtctg gattgccaaa
    30181 caactgcatg atagattgga cgtcctgtat ctttttccca tattactgtt gtttcacgct
    30241 ggttcgttat gccaatccca gcaatctgat ttggtttgat ccctgattcg atgaacgctc
    30301 cggcaataac tgactgtaca gaattccaga tttcatttgc atcatgttcc acccaacttt
    30361 cttgcgggaa atattgcgtg aactcttttt gagaactgcc gatgtgtctt cctttcttgt
    30421 caaagataat tgctcgtgag ctagttgtac cttggtcaat cgccatgata tacgttgatt
    30481 ctgtcattgt gattccctcc attatatgca aacgctttct ttaactactc ttatcatact
    30541 actgttttaa aaaaagaaac tgtcaaaatt ttattctttt tttctttttt tgacagtttt
    30601 ttattatgaa gctatttttt aatcaattct tttctttttt cagcgtctct attcttcttt
    30661 tcaatcgaat aatgtcgtaa ggtgacgcaa attctgacag ataatattca cactgttttt
    30721 tgtttctctg gcaaaatgtg atcaccaaat catattcttt accttcttca taacttccaa
    30781 tctcaatacc gccgattccc ctcagttctc tgatcagata ttgttgaaaa gcaatacgat
    30841 aaatcggcag actttctaaa tcgattccaa tcactactgg ttttgcaata taaaaatcga
    30901 tcatcaaaag aacattggca tactggatca tcaggtaact aagctcacta tcttcagctc
    30961 ttttcctcgg caattgctgc accgctgttt cctgtaattt cgccagtaac tgtgttaagg
    31021 aatgcccgag cattttctgc tgctgttcca aaagccgatc acgctcatag acttcgatct
    31081 ttccaacaaa gaaaaaccat tcattgttga tctgggaaat ttggtagcct actgcctttt
    31141 cttctttgat tttcaaacga cgaggacgat aatgccataa catcgtttcc cgaatgtaag
    31201 tatctaaaac agcggttggt aactttttgc tccgtgtcaa atcatactga taaaatattt
    31261 cttcgtctac tatcgaaaaa gaaacaaaaa agctgtaaaa catcattgtt tcgtatacat
    31321 tcagttctgc tgctgttcga ctaagatgca tcacgatgat tggatcgatt gcttgataaa
    31381 gccggtccga ctgatagagt aatttctttt ctttcaaagt tgcgtacgta cttttttcat
    31441 tcaatagtct ttttttcgta atcccgagcc agcaagcaat ctgtgcttct gctgatgccg
    31501 taaacgttgt ttctaataca cggtccaatc ctagaatgaa cggtcttttt tctggtgtat
    31561 tttgcaaaaa aagcggtcgc tgatcttccg ggatatattg gaatagttca taataaaaat
    31621 atcgtatctg tagctcttct ccgtataatt gaccgttttt gatttgtaat ccaaattcct
    31681 ctaagagctg gttcaattct ttgatctttc gaaaaacaga agactcactg atattaaacg
    31741 ctgtcgctaa tcgaacgatg gatacttgct gatgttctaa taaatagacg agcatcttaa
    31801 acttcaagct ttcctgcaat aaaaacaata gaattttttc caaacttaca tcttcgtcca
    31861 acacaagcag cgcctgatac tcatttcgct gtacttctac ttttttttcc atcattcggc
    31921 caatcaattc aatatcttcc aaatattgat caaacgaggc ttttgacagt tggacatgct
    31981 ctctcaaacc attgatagag gctgttcccc cttgcagaac aaggtttcgc aaaatcagga
    32041 tctgtaactg ctcttttctt tctaataatg cttcaatctt cataggcagt attcgccacc
    32101 tttgaccaca ccatatctgg cacacggtat tctggctgga aaaatagctc atgttcttct
    32161 aactgttcaa acgtccatcc ttcttctact gcaattgtca gttggtcaag aaggtggaac
    32221 atctcttttt tgctttggag ctgtgctcca agaatctttt tttcagaatc aaatagaaat
    32281 ttgagtttaa ctttgctttg atttattgct gtaagcttgt agtctacgta tcctgtttca
    32341 attttttggg gataaaaaat gctctcttct tctgtcaaac ctacgcttcc taagaaatag
    32401 ccaaaccact gattgccgac tggacgatag gttccctgat cctttgtctg tgagccacta
    32461 attgtcttgc tgacatttcg tgctgtacgg acagcgttat ttactagaga aacatacatt
    32521 ttttcatttg ttggacgaaa agttacttgg atcgcatcgc caatcgcata aacgtctttt
    32581 tgagacgttt gcaagtagtc atctacccag atcgttccat catcattcaa tgttaattgt
    32641 tcttcccaca tctgattgtc gggacgagaa tgattagcca gcaaaacaag atcatagttc
    32701 tcctttcttt tttccgtctc tacaatagcg gtttcatttt cggtcaaaga cacaacttgt
    32761 tcttctaaaa aaagtgaaag cccttgattt ttcatttcct ttactaacgg ttctgtcatt
    32821 tcaggatcta gataacgaaa aagaattgac tttcggcttt cgtaaagatg gatttgtttt
    32881 tttcttgatg ccaacccttc agctatttcg attcctgctt gtcctgcacc aataattgca
    32941 attttctttg cattcatgat cttttgctga agagccgtta cgttttgtat ctttttaact
    33001 gggtgaataa gcgttgattc tgcagaaata tttcgaaact tttgatttga accagtcgct
    33061 agaatcaaac gatcaaaatc caattttttt cctcctgcta aaacgacttt tttttctttc
    33121 aatcctatta ctgtcttttc tgtgtaaaca tggattcgat agcggtcagt cagttcttct
    33181 ttcgtgatcc aagaaagttg tttttcactg gtaacctttc cttttaatat caaattgaac
    33241 ccgctgggaa tccatcctaa cttcgattgc ttttcaatca aatatatttc acttgttggc
    33301 atcaattggc gaagataaat agccgcatga atccctgcaa acgacccgcc gacaattaca
    33361 atgttcatct gcattcctct ttcttataag gtgttctact gctaacttct caatcagaaa
    33421 acacagtatt cataactcgc tttcaacctt atgatacata gcgatgcagc agaatcaacc
    33481 ctctccatca taccgtgttc taggtctgct tctcaataat gtactagtgg acctaattga
    33541 agagtatcat ttctgaagag atgtttcaaa aaatgtactc ttataaaaga aaaaaactcg
    33601 ccttttacgt acctctgtcc aaataggaaa cagaaaagaa cgaaaagacg agttttagcg
    33661 tgtgtaatgt aatagttaga atagacacat catttatttt taattcttta atgcttcaac
    33721 aactgcttcg cctaattgat gagcagattg aggattttgc cctgtaagaa gccgcccatc
    33781 aatttgaacc acttctgaaa aagctgctcc agactgatag tttgctcctt tttctttcaa
    33841 agcatcttct gctaagaatg gtacttcatt cgttgtacca tttgcttcct cttcttcatt
    33901 actgaaccca gtcactgtac gtccagctaa aatagatttt ccagactcat ctgtaactgg
    33961 caacaatcct acaacaccgt gacaaacagc tgagaccagc ccttcatttc gatagatttg
    34021 tgaagcgact ttcccaagat ctattgcttc tggaaaatcc cacattgttc cgtggccacc
    34081 agcataataa accgctgcat aatcatttgc atccacatca tcaggacgta aggtatttcc
    34141 caaggcccga tttctgaaat cttcatcttc ataataggcc caatcgattt catccatatt
    34201 caaaacactt tgcggttcta aaggtacata tccgccttta ggactgacaa aatctgcatc
    34261 gatcccattt tttactaata catcataaaa atgagtcagt tcacttaacc acaaacctgt
    34321 aggacgctcg atcttttcgt acttttctac atttgttaat acgatcaata ctttcatttt
    34381 cccatcctct ttctataaaa attgcgttat tgataacgtg ctttcaagaa attatataat
    34441 gggcttggca aataaagctc tttatatgct ttttcaaaag gtttcgttac aaattcatcc
    34501 tcacggtttt ccaataattt ctctgcccag tcaggatcga cgatcatttg ctgtccaatt
    34561 gctgcaagtt ctgcatattt caatacctgc tctacatctt cgcgattgcg gatcccaccg
    34621 acaccaacta aagggatctt tccttgaatc gtgttatgga ccacttcaag aatcgattta
    34681 tcgttgtatt tatcagaacg agctattcga tcatacatat ttaatgaaac atgcagataa
    34741 tctagttttg actcacgtaa tcgttcaaga agccagatcg tgtcttcaaa acggatacct
    34801 ggtgtttcat attcttctgg tgagaaacga taccctacga tgaatggttt tttagcatat
    34861 tgttcaaccg ctgagaaaac cgttgttaat aattcttcaa taaaacgata acgattttcc
    34921 aagctaccgc cccattgatc ctctcgtcta ttcgaatgcg gagagaaaaa ttgttggatc
    34981 aaatacgtat ttgctccatg caactcgatt ccatcaaatc ctgattcaat cgctctacgt
    35041 gtggctttgc caaatgcttg gattgtttca acgatttctt cttcactcat tgctcgtggt
    35101 gtttccgcat caggacgttt tgctgcaact gcacttgcag atacaggctg ttctccagat
    35161 aaagttgctc gacttgtcat tcgtccaccg tggaaaatct gaataatcgc ttttgcgcct
    35221 tctccttgga ttgctttcgc tagctcactt aatcgaggaa tcatttcatc atgagcgatg
    35281 ctgagttcac ctggccagcc ttttccgata tcttggacat ttgcagcacc agtaataaca
    35341 gcaccaagac ctttagaacg ttgtttataa taagtgatct catcttcggt gatcactcca
    35401 ttgaaaaagc tgagttgtgt cgtcataggc gacagcatca atcggttctt caattgaact
    35461 cctgaaggta aagtaattga ttgatcaaat tgtgacattg tcattcctcc cataattcgc
    35521 tctgattaac ctatcgagaa tcatctatca ttaaaccact cgattagttg tacatgcaac
    35581 taatttgctt aaaaaatttt attttttttg taacttatct gttgcatcat tcattgtctg
    35641 ggctaattct ttacttgctt catttcccaa aactgctttg tatgactgat gaagttcttc
    35701 ccagctacca tcgacttcct tagcaaattg gcgtccttgt tctgtaagat aaactaatga
    35761 caagcgacct tcgctaactg ttttgacgta tcctttatat tctaattttt caacaaaacg
    35821 agcaatcgtt gatggggcgg aatagagcat ttgtgcaata tctttttgtg gtattccatc
    35881 tttttctttt aatatcaata aaataaaacc ataagttggt gccagacctg tccttctaaa
    35941 cgcttcatca gctaatttat tcaacatgcg atctagcttt ttcacgctaa agaaaagaca
    36001 ttcatctaac gctttttcaa ttggcttttc catttcatcc cctccattgg cgtacatatc
    36061 atagtatgat ttttattttt tgtcaaaaaa cacggaataa tgtccgcctc ctctgtctag
    36121 atttgaaaaa aagaagtagc catcttcaaa gaatttcggc ttgttttcga caaaactcct
    36181 tctggaacac cgtgaatcag aggttgtgaa aaagtcgttt agttttgagt atgaagaaaa
    36241 attttgtgaa aatggctttc cacatttttg cataaatttg gcttaatacc gaaaaactgg
    36301 cttttgaaca ccgtttatat cagaggttgt gaaaaagccg tcctgcatca agtaataaga
    36361 acagccaaac aaaaatagtt cctcatattt tgtcgttttt tgagctaatg ccgatggtca
    36421 gctgattgta caccgtttat tgagaggtcg tgagcctgcc gttgaactcc gagtcacaag
    36481 gagcaatttc aaaaaacagc ttctcatgtt ttatgactat ggtgacttgt gatcgaggag
    36541 ttggcaggag aatactgttt attcgtaaag aaggggctgt gacaagactt ttgtcacagt
    36601 cccttatttc cttttattat aggatttcgc catttgattg gatgacttgt ctgtaccaat
    36661 caaatgattt tttctttaac cgtttctttg tgccattccc ttcgtcatct tgatcaacat
    36721 agatatatcc ataacgtttt gacatttgtg aagtagaagc gctgacgata tcaatgcagc
    36781 cccacgacgt ataaccaaat aaatctactc catctttgat agcttccttc atctgctcaa
    36841 tatgctgctt caaatagtca atgcggtaat cgtcttgaac ggttccatct tcttctactt
    36901 tgtctatagc tccgagtccg ttttcagcta tgaacagtgg tttttgatac ctatcatata
    36961 attgattcaa agcaattctc aaacccttag gatcaatctg ccagccccat tcacttgatg
    37021 gaagatacgg atttttaatt cctccagtta ttaagtttcc ttggacccct tcccaatttt
    37081 ctggatgagc actgactgca ctagacatgt agtagctaaa agaaacaaaa tcaacagggt
    37141 aggctgctaa gatttcttca tcacctactt ctatttttaa gttgacacct ttttcttcaa
    37201 acattcgttg cgtatacgct ggataatatc ctcttgcttg aacatcacta aagaacaaag
    37261 aagttctttg ctgctcaatt gttttttgaa tatcatccgg atcacaagaa tacggaacaa
    37321 gaagctgata gctgatcata caaccgactt gtgaaccttt gataatttca tgacaagctt
    37381 ttgtagctaa agcacttgct ataaactgat ggtgtgcacc ttggtatttc gcttgttcca
    37441 aatggggatg gttttcttca attactccta cgctaacaaa agggtgatgt tttacacagt
    37501 tgatctcatt gaaagtcatc caatatttta ctttattttt atagcgtttg aatactgttt
    37561 cagcgaaacg aacgtaaaac tgaataagct ttcgattagg ccatccacca tattctgtaa
    37621 ccaaatataa cggcatttca taatgggaaa gagaaacgac tggctcaatc ccatatttta
    37681 gacattcgtc aaacacttga tcataaaaaa ataatcccgc ttcattgggt gtttcttcat
    37741 caccatgagg aaaaattctt gtccatgcga tagacatccg atagcattta aaacccattt
    37801 cagcaaataa acggatgtct tctttaaagt gatgatagaa atcatttccg tgtcttttag
    37861 gataataata cttgctgttg ggatcctgcg ccgcttttac ttgctgatgc gtcatcatat
    37921 gccattgatc tgtccatttt tctttaggta aatcgctgtc gaatgtatac acatcagaca
    37981 cagataatcc tttttcatct acatcccatg caccttcaca ttgattggcc gctgtcgctc
    38041 cgccccataa aaatccttct ggaaattttt tcatatcgat ccccctaaac ttgctagttt
    38101 tcttgtttga ttatttttct tatgactagt aatgatattt ttgaatctac tactatttgt
    38161 aacaataacc attgtggtcg gatcatatcc ctctttgatt aattcttgca aatctacttc
    38221 catcaataaa tcgcctttac gtactttttt tccatcagat actgcacttt gaaagtattt
    38281 gccatttaaa ttcactgtat caataccgat atggatcagt atctctgctc cttcttcact
    38341 gactacccca attgcatgtt tcgttggaaa aactgttgaa acttccccgt ttacagaact
    38401 gtagattttt ccgtccgttg gaatgatcgc aaacccttct cctaaagatc cactagcaaa
    38461 tgttggatcg tttacttcag ataaatcaat tatttcacct gctgcaggag tacttaacac
    38521 tatatccttt gaggattctt cttcgatttc atccttgtag ccgaaaagaa aagttagcat
    38581 acaggaactg atcatcgcta agaaataact agcaactagc caaacaaatc cttcaccaat
    38641 ataaatcggg aaagacaaaa tacttcttgt agcaactgcc aaagcaccgg ctcctgcggc
    38701 accagctact ccaccaaata tagctccaca tatacaagca atgtaaaatg gtcgtttata
    38761 tttaagagtc acaccataaa cagcaggttc agtgattcca aataatgctg tgataaatgc
    38821 agataaagat aaacttttta ctttcttatt tttcgttttc aaaaataccc caagtactgc
    38881 tcctgcttgc gcagctacgg cagtcataca tgctggacct agcgtatcac gaccgtagaa
    38941 agaaagattg ttggtcatta ctggtacaag tccccaatgt aacccaaaaa tcactaacac
    39001 ttgccaaaat ccgccgataa cagcaccaga taaaacaggg ctaaagttat aaacagctaa
    39061 atatccagct gcaatcagct gacttgcata atctgcaatt ggacctacaa ctaataaaat
    39121 aattgggacc atcacgatga tacaaatgaa tggtgtcaat aaatttcgaa tactttcgtg
    39181 caagcttttg cgaatcttag gctcaatata agaaagaacc catacagcta aaattgctgg
    39241 aataaccgta cttgtatacc ttgctagaat cacgggcatc cctagaaatc gcaaggttat
    39301 gctatcacta tatgcactga caatcgtagg ataaacgaga gctgctgcaa taaccatagc
    39361 gatgaaacga tctgtattga acttttttgc agcagtatat gccaaaaata taggcaagaa
    39421 atagaaaaat gcatcagctg ctgcattcaa aatgatataa gttcctgatt cagtagttaa
    39481 taaattcaaa ctcgtacata aggcgagtac tcctttgatc aaaccacttc ctgccaagac
    39541 gcctaaagtc ggggcaaaaa cagcggcgat catgtctata aaagagttta aaatgccttt
    39601 tttctcagtt cctctctttc cactagatgc atcatcttct agtttcattt gtttggataa
    39661 tacgtcatac acttcattta ctgcatttcc tactacgact tgaaacattc ctccagcttc
    39721 gactacagtg atcacacctt ctagttgctc taccttctcc ttatctgcct tcttattatc
    39781 ttttagggta aagcgtaacc ttgttgcaca atggtaaaca ttgctgacat tttcttcgcc
    39841 tccgacaaat cggacaatat ctttcgctaa ttgtgaatag tccattttta cttccccctt
    39901 gttaattaat gccgtagcaa tccttcttac aagataagta tagttcttag aaaacggttt
    39961 ctccattcaa ttagtacccc ttctaatagc gaacgaaact gtacaatagt gtgtatggtt
    40021 tacttagccg agcaaatcac tcactgcttg aaagaaaaca agtatatcgt ttctcttata
    40081 gtcaaaggag acaaaaaaaa cacgcttgat cttcctttgc tgatgtataa gtggtatctc
    40141 aagctgatac tctgtgattt ttgtttctac ttggcttttg ataagacagc acaacaaagt
    40201 ctcggcattt aacggaagca taactaggtc agaactagga gagattagtt gctgaatgga
    40261 atctatcttt ttatggattt ttatttgatt ttcttctttg tagtaatgat caagcagttt
    40321 tgttttcttt ttttcttcaa ctatggtcag cttttcacgc aaaatctgat aaatctccca
    40381 agattcaaac tcatctagaa cactaggtag ataaatcaaa tcatcccact caaaaataag
    40441 ctcttgctca gtagtcaaaa ttgcatcata ttccgttatt ttgtttgatt gatttttgaa
    40501 aagatacact ggttctatcc ggcattcttt gatccacatg ttcatacttt gttgaatctg
    40561 tttttttagt gtattcaaaa tactaattgg ctggttacta acaatcagta tctccccttg
    40621 ttttcgaaaa ggattcaacg cttcggcaag atacaaaaca aaataagcgc tttcagctaa
    40681 attgggacgt aattgaaaat gtattgggaa gaaacgccga attaaataaa tttctaaagg
    40741 ataacgggag atgatctttt gtacaaaatg attcatggta ttatgtccgg catccatcct
    40801 cgttttcatt tgtttgatat gggttagcaa aaattctgtt tcatggaaca ataacgaaac
    40861 aggaagatct aaaaaacgaa taatcgtttg ctcaaatgct cttagattct tctctatttc
    40921 tttgtttttt tcatcattaa tcatcaaata atttaactct aatagtcgat tttcaattgc
    40981 ttgtttttct tgattggaaa aagaataggg tagttctgat gataactttt ttgtgagggt
    41041 ctctaccatc ggaataaata atgtatacct gtttgttttt tctaaaagtt cttctcttcg
    41101 aagaatggtc aaaacgagat accgagaaaa tcgtatgaag tcctctcctg aaacaatata
    41161 attatatgat ataagaacct cttttaatgt cttttggaca gtcggcatga tattggaaaa
    41221 aattgtactg atttgttgag gaaaccttgc gtgttggatc accgtttctg ttccaacaag
    41281 agataagaaa attctttttg aattttcttc agcaatgatt tttagtcctt ttgtcgacga
    41341 aacttccagt tctaatttag gattgcgctc gatccaacgc aaaatcgttt ttatttgtaa
    41401 tgatacggct gtttttgaaa gaaagaaaat gtctgctatc ttttgcatac tgacataccc
    41461 tttttgaaac aataagtacg tcacaatagt tgaagctcgg aaatccatgc tggaatagat
    41521 tttatgtttc gtcacctctt gtatgatttg ctgtttagtt tcagattcaa ttgattctaa
    41581 aaaataacct gaacgtttat ttgactggat aatgattttc ttctcgtaga tagcaagcat
    41641 atttttgatt tcagtttgga tcgttttctt gttggtacct aaagcttcag ctaattcttc
    41701 gcttgttatc caatgattct tatttcttaa tactacaaga atttggagtt gtcgtttatt
    41761 taagtccatt tgcttacacc tcctctttgt tataaacata caggaaaaac ctctcaaatg
    41821 acaatagtca cttgcagagg tttaaaaatc atttgaagaa agatctatat tcaaggtttt
    41881 taccattaga ctggataatt tgtttataat attcaaaact atcttttttc aatctcctaa
    41941 agcttccgct cccatcattt tgtctatcca cataaataaa gccatatcgc ttcctcattt
    42001 cccctgttcc tgccgatacg atatcgattg gtccccacca taagtaacca atgatttggc
    42061 aaccatcttt tattgcctca gcaatttcct gaagatgtat ttttagatac tcacaacgtt
    42121 ttggatcgtg gattcgattc aattcatctg gtgcttcatc tagtccaatg ccattttcaa
    42181 ctatgaataa tggtaattca taacggtctg tcaattcatt catgacataa cgaaacccta
    42241 gaggatcaat tggccaactc caaggttcgg gagatttttc cttcaaaaag ggattatcga
    42301 aaccatttgc tccgccagta tctacgcgca tttctgcttc ttttttatag acagcgctac
    42361 gataataact aaatgcaata taatctgccg tgttagcttg caagcactgt tcgtctccat
    42421 ctaacattac tggtgcacag tcttcttcct tccatgtcct gtaaatataa gctggataat
    42481 gccctcggca catgacatcg gagaaaaacc atgaattgcg tttaaattgc agtgaaccaa
    42541 atacattctc tggatcacag tcatatgcat aagtcgctaa tgcagaaaag ctacacataa
    42601 tacccatctt agcatttgga tcgattttct ttaataattg agtagcacgg gcgttcgcta
    42661 gaaacatatg atgacaggct tgataaatca ctttttttgt tagtgtagca atgggttcaa
    42721 gtttatctct agcagggaat gtaaccaatc cagcagctgc ataaggcata cgaaaagcat
    42781 tattgatctc attaaaggtc atccaatatt tcactttccc ttggtagcgt tcaaagacgg
    42841 tctgcgcata aaattcaaaa aagtcgatta attttcgatt ttgccacccc ccatactctc
    42901 ctaccaatgc taagggggtt tcataatgac taagagtaat tactggctcg atatcatatc
    42961 gatttaatgt attgattagt ctgtcataaa atacgagacc agcctcattt ggcttctgtt
    43021 cgtctcctct tggaaatatt cgtgcccatg agatgcttgt tcgaaaagct tttaaaccta
    43081 actccttcag taaacgaata tcctcttcaa atcgatgata aaaatcaatc gcttcatgag
    43141 aaagataatg gagtgattcg tctaaagcaa tctcccaaat ctttttttct tcattccact
    43201 gaatactagg atgctggttc atgatcccga taagcgtatc tgtcacatta ggtaatttgc
    43261 cgtcttccaa ccatgcacct tcacattgat tagcagctac tgctccgccc cataaaaaat
    43321 tttctggaaa tatttcctga tccataacta tctctcctcg ctatcaacaa tttcttactt
    43381 gaagtatagc tcgattcatc aaaacaagat attctaacta tttcggcaga agagaagaaa
    43441 aaaattgaat gctactcttc atttttaata tttatatata acaaatacat aagacgatcc
    43501 ccgaaagaaa acactcgtta accatctaag caaacgattt attttacttc caacacaaat
    43561 gcttcataag gtcgtaaatc aactttgccg tctggtaact gtttcagagg ataatttgac
    43621 acaataaccc ttaaagcttc acgtggaata gtgaacgtct gcttttcact ggacatatta
    43681 caaataacga gccattgctg gtcttcatat atgcgagaat aggcaaagac atgctcaggc
    43741 gtcttttcca ctaattcata gtctccccag acgatgatgt catgttttct acgcaaatcg
    43801 atcaatttct tgtacatata aaaaacagaa tcttgatctg ctaacgcttc ttctgcattg
    43861 atttctttat aatttggatt gactcgaagc catggaattc cagtagtaaa cccagcatgt
    43921 tcacgggcgt tccattgcat aggcgtccta gcattgtctc ttcctttcgc cttgattgat
    43981 tccaagattt cctcttttgt aaatccagaa gaaatccttt cgttatacat attgattgtc
    44041 tcaatatctt ttgcttccgc gatatcatcg attgggcaat tcgtcatgcc taactcttct
    44101 ccttgataga tataaggggt gcctttcatc atatggagca agatagcaaa catcttggca
    44161 ctttcttttc gatacacatc gtcatttccc caacgagaaa caattcgcgg aagatcgtga
    44221 ttattccaaa ataaactatt ccatccttca tcacctaaag atgtttgcca tttggataat
    44281 acttttttca gttcagagat actcaagggt ttcaaatccc atttgtcttt gccttcttgc
    44341 tgatctaatc ctatgtgttc gaattggaag accatggata attcatttct tttaggattg
    44401 gaataaagtt tagcgatttc ggtagttgct ccccatgttt cgccaacagt catcagattt
    44461 ttgtcaccaa aagttgcttg attcatttcc tgaagatact catgcagttt aggtccatta
    44521 cttgtgattt ctttatccgg ttctttgcca atcatatcga tcacgtccat acgaaagccc
    44581 ccaatacctt tatcgatcca gaaattcatc atttgataaa tctcttggcg aacctgttta
    44641 tttttccaat tcaaatcagg ttgacgcttg ctatacaagt gcagaaaata ttgccccgtt
    44701 ttttcatcca actgccaagc agaaccactg aatattgagc gcaatctatt aggctctttt
    44761 ccattgaccg gatcacgcca aatataatag tcccgataag gattttcttt atttttacgg
    44821 gcctcaatga accacggatg ttcatcagaa gtatgattca ccaccagatc catgatgata
    44881 cggatatttc ttttctttgc ttcttcaatc agttcttcca tttcttccat cgtaccgaat
    44941 tctgccatga ttgcttgata attactgata tcatacccat tgtcatcatt cggagactcg
    45001 tatactggag aaagccaaat tgcatcaata cctaaatacg ccagataatc caacctggaa
    45061 ataatccccc gcaaatctcc aataccatct tgatttgaat cttgaaaact tcttggatag
    45121 atttgataaa caactgaatg gtgccaccat ttttgttcca tgattttcct cctataaatg
    45181 gatgtttcta ttttttgctt aatcatttat tttagtctct ctcactaaaa attgtaacgc
    45241 tttcaaatag ctattgcacc ttgttatcgg taacagaata aaacaaaaaa acagctgagg
    45301 aaattccctc aactgttttt tgaaaggatt gatttatgca gggaagaatg ctgatttcac
    45361 aacttcttta taaacggtgt tcactcagct gtcccttggt attagctcaa aaaacggcaa
    45421 aatataagaa actatttttt cgtttttttc tctaatactc aggccagaac gctgatttca
    45481 caacctcttt atttcacatt caatatccac atgaatccca caaatacaaa gaacagacca
    45541 tacatgattg gagatacttc ttttcctctt ttagctgcta acatggtaat tggatagaag
    45601 ataaaaccta atgcaatccc atctgaaata ctataagtca aaggcatgcc gatcaagatc
    45661 aagaatgaag ggatcgcaat ctctaagttt ccccattcga tttgtcgcaa agattgtgcc
    45721 atcaatactc ctaccataat caatgctggt gcagttactt gtgaagtaac aactgatagt
    45781 aatggagaaa agaacaagcc taacaagaag aaaatccctg tagtaatagc tgtgatacct
    45841 gaacgtcctc caacggcgat accagctgat gattctacaa atgcaccaac aggagaagta
    45901 ccaaataagg aacccgcaag catagctgtt gaatcagaag ctaaagcttt ccctacacga
    45961 ggcatcttgt tgtctttcat gaaacctgct tggtttgcta atccaactaa agttcctgct
    46021 gtatcaaaga aagtcacaag caagaatgtc agcactacga cccacatttg aagagaattg
    46081 atgtccccta catgttttaa tgcaactaaa aatgttggtt tcaaacttgg tgctgcggca
    46141 acaatttcag aaggcattgg aatcaaacct gtgaccagac ctaaaatcgt tgtagctgcc
    46201 atcccgatga agatgccacc tggtacacgc cgaacaagca agatagcagt tacgactaat
    46261 ccaaaaatcg tcaaccaagt agaaccaacg ttgagtgatc ctaatcctac taatgtagat
    46321 tcattcgaaa cgatgatccc accttcgctc agaccaagga aagcgataaa tagaccgata
    46381 ccgccagaaa tcgcatattt caaatctgct gggatcgcat caatgatcat ttcccgcagc
    46441 ttgaagattg tgatcaaaat aaaaatcaaa gaagcaacga atacgccggc taatgctgtt
    46501 tcccatggaa tccccattcc taaacaaaca gaataagcaa aaaaagcatt gatcccaaga
    46561 gcaggtgccg ttccaattgg ataacgggct aataccccca ttaaaacaca gccgatcgca
    46621 ctggctaatg cagtcgcagt aaacactgct ccttcatcca ttccagaagc acctaataca
    46681 gttggattta caaataagat ataagccatt gagataaatg ttgtaaatcc tgccagtacc
    46741 tcacgtttta ccgtggtgtt caatttttct atttcgaagt aggaaagtat tttttccttc
    46801 atcttccatc cccctaaatc cgaacattat aaataaagtc cgttaaaatt tcgatttatt
    46861 aataaaacaa cgtgttttat catatactaa aacaaaacat aagtaaacaa aaaattcgga
    46921 ttttaagcaa aatccgaacg ttccatctga ttaaatccct ttatctcaaa gttcatgaac
    46981 attcactttg gattacaaga atttctttat tgtgttaata aagtttcttc attctagtct
    47041 caaaaatcaa tagtgtgatt tgattttacc atttcgtttc tgttcttctt tgatgaattc
    47101 ttttgtatcg acaggattca gattatttag tccgccaaaa cctgtatcga ccatttttcc
    47161 ccagcctttt gtcttctttt ttcctgattt gagattcttt gctcgaagct tctcactatg
    47221 ttttgctcgc cgatacttca aataaccttc taatcttccc attagatcca ctgtttttcc
    47281 tcctttttat tcaatcagac gactcagctt ttcctataac aaaataattg ccttcagggt
    47341 cagaaaaatt gaaagtcaag atgccattgt tatctgtgat ttctcctggt tcttccatgt
    47401 tctcgtagat agtttcaaat tcatccgtaa aaaatactaa agaaggcggt ggtcctaata
    47461 cctctggtga aaacttctgc acaaatactt ttgggaatac gcctaattct aattcttttg
    47521 agatgctgag tacaatactc ttaaattctt ctggcaattc gattgtttca gaaatttctg
    47581 caccaatttt ttctacaaag aatcggcaaa tcatctctac gtcattgaca taaagcatca
    47641 cacgtgtttt ttgtatcatc atttgaccct tctttctatt tgattttctt tcctgtctat
    47701 aaactgattc cattatatca cgaaagcgca aacaccttgt gtttgatact attcaagaaa
    47761 aataaagcaa tagtttctag gattgctttc ctccacaaac tttttttaca aaaaaaaaac
    47821 ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct gattcatctt
    47881 tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt tccttcaacg
    47941 cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca atgaccagca
    48001 ccgctgcttg tgtttcttcc gtcagcatcg ttctttgggc ttcacgccag ttgagacagc
    48061 gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc ggagcatcgg
    48121 aatctgcacc taaaggcagg aatgattcgc caccttgggc ttttcctaaa tgcagatttc
    48181 ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag gaaatactat
    48241 tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt gcacgtttca
    48301 gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta aatgcctgac
    48361 gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa tttcttgctt
    48421 cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt gttacgtggt
    48481 tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact tcccagaaat
    48541 tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata attgcttgat
    48601 gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc tgtatttgat
    48661 aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa caccgagcca
    48721 aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta aaaatgtacc
    48781 gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta aaaaatgatc
    48841 agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg caggctcttg
    48901 atcgatactc actaggaaaa aatcggtttc tttatctttt agctcttctg taagtttttc
    48961 tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtgaattat cttttccaaa
    49021 tgtatctgta aatgtttcga tactaatttg ttgtagtaag tctacatctg aaggcgtcat
    49081 ttttcgaatt tcgtatttat tcacggcttc ttcctttcaa tagatccttt tattgccttt
    49141 tttgacaaaa ttccaatctt cgctaacatt cttgcatact ttatttaaaa gatattccaa
    49201 ttgttttgct tcttcgtcag aaagaccatt taatgcgact gcattggagt agttgttttc
    49261 tcgaatgatg aaaggataga tttctgctcc ttttttagtc ggatagagtt tcttgatttt
    49321 tttattttct ttatcttcca aacgttcgat catcccattg gattctaatt tcttgattgc
    49381 tcgggcagtc gttgtacgat ctactttgat catttctgct agtttttctt ggatgattcc
    49441 aggattttcg caaatacgta ctaaataaag atactgtcct cttgttaaat cgacttcttt
    49501 gaattcgata ttgctaatag aatctagcgc tcgggcaatc attccgatgt ctcgaaggat
    49561 ttcagccatt tcatcccacc tttattttgt ttgtaagact agttcacctc tttttgttgc
    49621 aaatgcaact attttcaata aaaaaatcaa gttctttttt aataactagt aaagtatatt
    49681 cttttcttct tttacgaaaa agctcaatca caatagatct ggtttttgtt ttctaaaata
    49741 agtaactgtt tcttcgttgt tcgcttttct gatagctttg gcaactcttc tatactaaaa
    49801 aatcccatgt tggaagtttc attattctca ataaacttgg cctcttcacc gtggatcgca
    49861 caagcaaaaa caagtttata atactgaaaa agctgtggaa tatctttttg tttattcgta
    49921 tcaaaaactg ctcgcaactg agtagtttct actgttaatc ctgtttcttc atagacttct
    49981 ttacgcacat tttcttcagg agacaatcct atttcagcaa atccaccagg aagtgaccat
    50041 tctttcgtcc gtttatcttc gattagtagg accttgccat cttttttgat ataggcacga
    50101 acatctactt ttggtgttgg atgtccttct ccaatcgttg tgagcgcttt tatttcttcg
    50161 aaagtttctt ttcctatttc actgatcagt tccaatgaaa tcgtccggat ctcctcaaaa
    50221 cgctctttat caaatacatc ttttccataa tatagaccag cttgagaaag tgcgagtagt
    50281 cttttgtatt gagccaactt cttgttcatt ctcttccctt cttttttagc aaatgtatga
    50341 ctatgtaatc aagtatagaa gactggttta attacggcaa ataaatataa tgaaatctgc
    50401 aataaataaa agaatgttaa aaaactcgag aacaaaagac attcgacttc tctggggctg
    50461 tgaataaatg gcgttcaaaa gcttgcatct gcggtaataa gccccaccaa acgaaaaata
    50521 tgacgagcta ttcttgtctg gctgttctta ttaattgagg caggacagct ttttcacaac
    50581 ctccccacta aacggtgttc tcctaccaac tcctcggtca caagtcacaa tattcatcaa
    50641 acatgagaag ctgttttttt gaaattgctc cttgtgactc ggagctgaac gacaggctca
    50701 cgacctctcg gtaaacagcg ttcaaaagcc aatttttcga tattaagcca tttctttgtt
    50761 acttattgtc attgatttct ttttctaatt tatccaatag tggagtgtaa tccacttgag
    50821 tatagtctgt tacatcaaat tcatatagtg ttcctaactg gaatttgtca tattttcggt
    50881 cggcgatgat ctttttgaat gcttctttcg taatatgatt ggtccctttc gttcgatctt
    50941 ccaatacgtc accatagtga taatgatcca tgatatagct caaatgacga tctgattcac
    51001 gatcacgttt gtaccgacgt tgccataaca cttcaaagtc tgctgttagg cgaatcgtga
    51061 tcacctgata tccgtatcta tctgctaatt cttggagtcg tgctttttgc ttatcactaa
    51121 aaggatactc ggacacaatc actttctttc ctgcttccat atacaaatca agtgctttgt
    51181 aatagaaagg ataaactttc gtcctttctt gttccgcccg ttcttccaaa ttgttaaacc
    51241 cgatggattc tgcatagtat tccttgattt catcgagcgt gatggcatac atatctggaa
    51301 atcgttcccg tagtttattc ataagatatg tttttcctgt accaggacta ccagccagaa
    51361 gaatgaaata ctttttcatc tcatttattt cctaagttaa ttggactttc caagttcata
    51421 aacagtccaa tcttatgctt gacaatttct tttactgctt catttgctgg aatcacatta
    51481 tggcgaagag acttgttgat ttctgtttca ctaaaggttt ctttagctac tttcgtccag
    51541 ttgactaaaa gctccgttcc aacattgaat ttgcggatcc cgttattgat caattcagga
    51601 taatcttctt ctttcacacc tgttcctcca tggataacta gggggacatc aactactgca
    51661 tcgatttctt tcagcaaggg aatgtttact tctgtttttg atttgaattg tccatgattc
    51721 gtaccgatag caatagctaa tgcatccacg cctgtagctt ctacaaattt cactgcgtct
    51781 tccggtcttg tatatacctt gtcattttca gcgacatgga ttccttcttc tgtaccgccg
    51841 attgttccaa gttctccttc tacggaaaca ccgtgcgcat gggcatattc tactactgct
    51901 tttgtcttca ggatattttc tttgaaaggc agatgggacc catcatacat gacagaagta
    51961 tatccgctgt cgattgcttc tttgatatca tcaaagtctc gggcgtggtc taagtgcaag
    52021 actgcatcaa ccatttcttc ttctgcaata gctgtcatta cattgactaa cacatgcatg
    52081 ccgatatatt tagcggtatc gacacttgtt tgaataatga tcggcgaacc catttctttt
    52141 gctgcgccta gcatagcagg aagcatttct aggttatgcg tattaaaagc tccaactgta
    52201 aaattcaact cttctgctgt ttttgttact tctttcaatg ttgtatacat cttttattgc
    52261 caccttatct ttttatttgt ttcctttgat cgttacttgt tttgcaattt gtcgcatctc
    52321 atccattttg cccatgtagt aatcgatccc ttgatcatca ccagcacgag cagcatctgc
    52381 acgcttctgg ttatagaggc tcatcagttt tttataccca tctccgatcg tctgtttatt
    52441 ttccaaactc ttttctaaat attggatggc ttgatcgttc acatacaatt cagaaaattt
    52501 aagtccaact tgttcataaa gtttcgctaa tttatgctta tcttgggtag tggaaatctc
    52561 ttgtttcaat tgtgtaatct ctgattgaat cttttcggtc gcttctggcg atagggcttt
    52621 ttcttctttt gccagaactt ttttcggttc tttttctttt ttcttaaaaa atccaaacat
    52681 cattttccct actttcaatt aaaatgcttt caaaactggg cttaagatcc aggcatataa
    52741 gagtgctgcg gctactgtat ctacatcggt tgctgtagca ttgttgaatc ccatcgaatt
    52801 aaagatcgtt actagcaaag cgggcaataa tgtaataaag aaaccatgag caataccgcc
    52861 aatgatcgct cctcggcgtc cgccaactgc gttgccaaat atccctgctg tccctccggc
    52921 aaagaaattg gttagcatac caggtaaaat catcgctaag ccgaacatgg gcaaagtaaa
    52981 catggcaata atcgtaccaa tcgttgtcgt aatgaaacct aaaatgacag catttgggct
    53041 ataaggaaag aaaactggac aatctaaggc agggatcgca tcaggaacta atttcatagc
    53101 tatccctcga aatgccggca cgatttcacc taacagtaga cgtacaccag ctagcaatac
    53161 atacacaccc actacgaatt ggatggcttg taaaaaggca aacatgatat agttttgatc
    53221 tcctgataat tcagaagcga atggttcgcc tgcaaataaa acagtgatga tatatagcgg
    53281 gaccatcacg accatgacag acaaataagt atcttgcaga aattcgaaat gtgtcggcaa
    53341 cttgatatct tcgatcgact ttttattttc gcctttctca ccaaaaagct tagcaacacc
    53401 ggcttcaaat aagtacccga tcgtacaaaa atgacctaaa gcaatatcat ttgatccagt
    53461 gattttacga atgatcggtt gcgctactgc cggcatagca atggcgaaac aagctccgat
    53521 aaaaccaccg accaagatca atacgatccc tcgcagaccg gcaaaatagc caaagactgt
    53581 cgtcatcgtt gccatccata aaattgcttg accagttaaa aaaatgtact tccattttgt
    53641 gaaacgagcc aaaataatat tgaatacaaa aatggctaag aacgtcagtg caatatctct
    53701 acctaaaccc aaatcattca ttgcttgacc attgatagat tcaatagaag ggatgatccc
    53761 ttgcatatga aatccttcag taaagatttt cccgaaataa gttaaacttc caacgatgat
    53821 gctcgaaccg gcactcaaca cttgaaatcc taggagtgtc tttaacgtgc cagagatgac
    53881 ttgtcctgct gatttcttct gcagtagtag acccaacata gcaatcaatg caatggtgat
    53941 cgatgcctga gtcaaaatat tttcgatgat aaaattgata acgcccatgt t
//
LOCUS       DAFKHN010000010        53431 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFKHN010000010 DAFKHN010000000
VERSION     DAFKHN010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.010"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            45..1416
                     /gene="nhaC"
                     /locus_tag="LY912_000593"
                     /pseudo
     CDS             45..1416
                     /gene="nhaC"
                     /locus_tag="LY912_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(1697..2716)
                     /locus_tag="LY912_000594"
     CDS             complement(1697..2716)
                     /locus_tag="LY912_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6954311.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2738..3745)
                     /locus_tag="LY912_000595"
     CDS             complement(2738..3745)
                     /locus_tag="LY912_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBM6954312.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3738..4403)
                     /gene="pgmB"
                     /locus_tag="LY912_000596"
     CDS             complement(3738..4403)
                     /gene="pgmB"
                     /locus_tag="LY912_000596"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBM6954313.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4396..6690)
                     /locus_tag="LY912_000597"
     CDS             complement(4396..6690)
                     /locus_tag="LY912_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBM6954314.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6950..9115
                     /locus_tag="LY912_000598"
     CDS             6950..9115
                     /locus_tag="LY912_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBM6954315.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9419..10252
                     /locus_tag="LY912_000599"
     CDS             9419..10252
                     /locus_tag="LY912_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBM6954316.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(10354..12054)
                     /locus_tag="LY912_000600"
     CDS             complement(10354..12054)
                     /locus_tag="LY912_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954317.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12561..13721
                     /locus_tag="LY912_000601"
     CDS             12561..13721
                     /locus_tag="LY912_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBM6954318.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13737..14180
                     /locus_tag="LY912_000602"
     CDS             13737..14180
                     /locus_tag="LY912_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6954319.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14663..15193)
                     /locus_tag="LY912_000603"
     CDS             complement(14663..15193)
                     /locus_tag="LY912_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBM6954320.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            15298..15849
                     /locus_tag="LY912_000604"
     CDS             15298..15849
                     /locus_tag="LY912_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBM6954321.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(16002..16475)
                     /locus_tag="LY912_000605"
     CDS             complement(16002..16475)
                     /locus_tag="LY912_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBM6954322.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16613..18085
                     /locus_tag="LY912_000606"
     CDS             16613..18085
                     /locus_tag="LY912_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBM6954323.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            18082..18792
                     /locus_tag="LY912_000607"
     CDS             18082..18792
                     /locus_tag="LY912_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBM6954324.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            19144..19428
                     /locus_tag="LY912_000608"
     CDS             19144..19428
                     /locus_tag="LY912_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBM6954325.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(19709..20128)
                     /locus_tag="LY912_000609"
     CDS             complement(19709..20128)
                     /locus_tag="LY912_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBM6954326.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(20130..20714)
                     /locus_tag="LY912_000610"
     CDS             complement(20130..20714)
                     /locus_tag="LY912_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBM6954327.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(20761..22236)
                     /locus_tag="LY912_000611"
     CDS             complement(20761..22236)
                     /locus_tag="LY912_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBM6954328.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            22417..22728
                     /locus_tag="LY912_000612"
     CDS             22417..22728
                     /locus_tag="LY912_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954329.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(22843..25179)
                     /locus_tag="LY912_000613"
     CDS             complement(22843..25179)
                     /locus_tag="LY912_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6954330.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            25321..25989
                     /locus_tag="LY912_000614"
     CDS             25321..25989
                     /locus_tag="LY912_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6954331.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            25992..27035
                     /locus_tag="LY912_000615"
     CDS             25992..27035
                     /locus_tag="LY912_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBM6954332.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(27272..28153)
                     /locus_tag="LY912_000616"
     CDS             complement(27272..28153)
                     /locus_tag="LY912_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBM6954333.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERALRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            28312..29040
                     /locus_tag="LY912_000617"
     CDS             28312..29040
                     /locus_tag="LY912_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBM6954334.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKSCGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            29196..29513
                     /locus_tag="LY912_000618"
     CDS             29196..29513
                     /locus_tag="LY912_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBM6954335.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            29506..30114
                     /locus_tag="LY912_000619"
     CDS             29506..30114
                     /locus_tag="LY912_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBM6954336.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            30169..30960
                     /locus_tag="LY912_000620"
     CDS             30169..30960
                     /locus_tag="LY912_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBM6954337.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            31098..31586
                     /locus_tag="LY912_000621"
     CDS             31098..31586
                     /locus_tag="LY912_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBM6954338.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            31637..32509
                     /locus_tag="LY912_000622"
     CDS             31637..32509
                     /locus_tag="LY912_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBM6954339.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            32685..33047
                     /locus_tag="LY912_000623"
     CDS             32685..33047
                     /locus_tag="LY912_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBM6954340.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYIQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            33056..33808
                     /locus_tag="LY912_000624"
     CDS             33056..33808
                     /locus_tag="LY912_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954341.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            33822..35624
                     /locus_tag="LY912_000625"
     CDS             33822..35624
                     /locus_tag="LY912_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954342.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            35901..36941
                     /locus_tag="LY912_000626"
     CDS             35901..36941
                     /locus_tag="LY912_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBM6954343.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(36993..39137)
                     /locus_tag="LY912_000627"
     CDS             complement(36993..39137)
                     /locus_tag="LY912_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBM6954344.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(39494..40867)
                     /locus_tag="LY912_000628"
     CDS             complement(39494..40867)
                     /locus_tag="LY912_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBM6954345.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(40867..41262)
                     /gene="rbsD"
                     /locus_tag="LY912_000629"
     CDS             complement(40867..41262)
                     /gene="rbsD"
                     /locus_tag="LY912_000629"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBM6954346.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(41290..42207)
                     /gene="rbsK"
                     /locus_tag="LY912_000630"
     CDS             complement(41290..42207)
                     /gene="rbsK"
                     /locus_tag="LY912_000630"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBM6954347.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(42315..43328)
                     /locus_tag="LY912_000631"
     CDS             complement(42315..43328)
                     /locus_tag="LY912_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBM6954348.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(43409..44011)
                     /locus_tag="LY912_000632"
     CDS             complement(43409..44011)
                     /locus_tag="LY912_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBM6954349.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILTNN
                     DLLAKTLKRTAALKVLVNVDITTFSYLSHQTDAGGISALSAPAEFTDLLLKDSLKDTN
                     NMLTITNYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLA
                     EDACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            44196..44897
                     /locus_tag="LY912_000633"
     CDS             44196..44897
                     /locus_tag="LY912_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954350.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            44907..47618
                     /locus_tag="LY912_000634"
     CDS             44907..47618
                     /locus_tag="LY912_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954351.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANIGNGSVDYFVYLPESAFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKITEGKAQIAQGRTQ
                     LEDAKKQLAQQSAAIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            47964..49592
                     /gene="treC"
                     /locus_tag="LY912_000635"
     CDS             47964..49592
                     /gene="treC"
                     /locus_tag="LY912_000635"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBM6954352.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(49652..50833)
                     /locus_tag="LY912_000636"
     CDS             complement(49652..50833)
                     /locus_tag="LY912_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBM6954353.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            51085..52608
                     /locus_tag="LY912_000637"
     CDS             51085..52608
                     /locus_tag="LY912_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBM6954354.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(52677..53405)
                     /locus_tag="LY912_000638"
     CDS             complement(52677..53405)
                     /locus_tag="LY912_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6954355.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
BASE COUNT        16699 a         9598 c        10916 g        16218 t
ORIGIN      
        1 ttttttcatg gcagggcctt ttcatttgaa ataggagatc gacgatgaat aaaaatattt
       61 ctttaaaaga aagtatcgct gtattgatcg tgttgttggc actcctagga gtactgatca
      121 tcggattcca gctctcgcca catatcccga tccttgcagc tttcatgtgt ttgttgtttt
      181 atggcagatt taaaaagttc acatgggatg agatccatga cgggatcatc aaaggaatca
      241 ctccagggat cattccaatc ctgatttttc ttttgattgg tgtcttagtt gcttcatgga
      301 ttttatctgg aaccatccct acgattatgg tttatggatt taaacttgtt tctgtgcgtt
      361 tctttttacc gacagcattt cttgtttgtg caattgtcgg agtgactgtc ggcagttcat
      421 ttacaacgat ttcgacgatt ggaattgctt ttttggggat cggtcattta cttggattca
      481 atgatgcaat gactacaggc gcagtcgttt ccggtgcctt tttagggaat aactgctcgc
      541 ctttatcaga tacgaccaac ttggcagcgg gtattggagg agttaatcta ttcgaacata
      601 tcgctggtat gcgttatacg gatttcccag cattcgtcct ttcgttgatt ttttatacga
      661 tattaggaca taacagtcat tcagccgatc tagctagtat caatgaaatg atccaaaaca
      721 tgaaagcgag cttttggatc tctccttgga cattgattcc actagttatt ttatttgggg
      781 gggcaatcaa aaaaattccg gctatcccta cattactagc gggatcgaca gctgctctcg
      841 ttctttcttt tatccatgag aaaagtttga cggtcggaaa agcagcagac atcttgatga
      901 atggttggtt atgtcgcaaa tacacctgat ccaaagctag atgaactgct ttctcgaggc
      961 gggatcatga gtatgttagg ttctgctagt ttgattttac ttgcattggc attaggtggg
     1021 ttactgatca aatatctgat cgttgatacc atcgttcaag aattaaaaga aaagatggac
     1081 cgaccttctc gtttagtcgg gtttactgcc ttgagctgta tcggaatcaa tctgatcgtt
     1141 ggagaacagt atctgtccat cattcttcca ggagaaacat tcaagcgttc ttttgatgac
     1201 gttggcttat caaaaaccta tttgacacga acactagcgg attcaggtgc gaccgtcaat
     1261 tctctcgtac cgtggggagt cagcggcaca ttcattatgg gaacgatgaa agttagcgcg
     1321 ttgcattact tgccattcgc ctttttctcg attcttgcac ctgtctttac aatattaggc
     1381 ggttttttat tgaatcgtcg acgtgtaaaa aattgaagga aggaaaaaag aggctgggac
     1441 agaagcgttt aactccaaga aataagaaga aactcaagaa aattgctttt taaatttttg
     1501 tgaatttcag cttatttccg aaggagttgc ttctgcttcc gccgtttata cgtgtttaga
     1561 gcgtgagaca aaagtgttct ttacttttgt cccacgctct tttttacaga taaacaatgt
     1621 gttagaagta gtatcttctt ttacataaaa agctgaccat aggataaatg gtcagcgtat
     1681 ttagtgagtc agctatttag tatgggtttt ctaaaggaac gactgtctct cttttgatca
     1741 agcgatgagg gatgaccaaa cgtacgccac tgctcaattc ttcatggatc aattcgcgca
     1801 gcttttgcat agcgacacgt cctaattcgg agatatcgat atcgatactt gtaaggtaag
     1861 ggtgtgttaa tgttgagaag atcgagttgt tgaagctaat gacggagagt gtctctggaa
     1921 tgacatagcc atacatttgc gccaactgca tcgtgcgaag ggcgaagata tcgtcaatga
     1981 ccaccaatgc tgtggcttcg ttttctttca acgttttctc aaaggacaga taatcctccg
     2041 gatgctctag tactacactg gataacgcag gaagaccagc catcatcatt gctttttgat
     2101 aaccgaaata tcgttcgaaa tacaaacttt catgagtcgt gtttgtcaca aacaggatat
     2161 tcttatgtcc attctggatc aaaaattctg ttgcttgttt acctagaagc tggttatcat
     2221 tatctacata aacgatttcg ttctcatgat gataaggctg tccgatcaaa gtgaaaggga
     2281 tgtggttttg gtataaataa tcaatgacag tatcttgact atctgaatac actagaataa
     2341 aaccatctac ttgtttttgt aaatgcatac gctggacgtt ctctaacagc aattcaaaat
     2401 ttttagcagt agcgattgct gtagtcatat cataattccg cgcttcttcg ttgattgctt
     2461 ccatgatctc aagataaaat gggttaccga tccgctcttt tgaatcaaga gggggtaaga
     2521 ttacgccgat ggcactggaa atgcgttttc ctagattgcg ggcagtcatg ttaggaacat
     2581 aacctagttc atccataatt tttcggactt tcttctttgt tgtctcggaa atactaggat
     2641 gatcgttgat gacacgagag acggtcgagg tggcaacacc ggcttttttc gccacatctt
     2701 ttacggtaat agccatgata aaaacacctt tctcttgtta ttgtgcagag aaccgataaa
     2761 tcgtctgact gatccgttct tgaccaggat ggaggttgat cgatccaaat ttggggaaat
     2821 gaacgatatc agggatttct tgcggttcga ttgctaatcc gtagtttgaa tgcatctgtt
     2881 ttccattgac agagaaatca gcttcgaatc cagtcgtaga aaataatacc atacttttat
     2941 tagaagttgc tatagtcatt tggcgaccag aatgcttctc gaataattgt aaggaagttt
     3001 tggaaagcct aggatgatgc aaaagaaata catcatctag tccatctgga taacatgcaa
     3061 ggatctcttg cagtgttggg gattttctaa agtcgattgg cagtttttct ttttttgtcc
     3121 aatttccagt aggcagtttt tcttgatcta attcaagcac accatctaaa aagaccgtta
     3181 actgatgttc atagatgtct cttgttccat ttcctgaaag gttgaagtag gcatggttgg
     3241 tcggattgca gatggtttca acaaggctac tagcagaggt tgtcatctct aattcgtttt
     3301 ttgttaaacg gtaagtgatc gtagcagtga ttggtcctgg ataggtagaa aattcatctt
     3361 ttaagtaaaa gaccacacct attgatgatg gagttttgaa aacttctact tcccaaaatt
     3421 ggaaagacca gcctttcgtg ccaccgtgga tatggtgtga tccgcagttt ttctccaatc
     3481 tatgctcacc ccaagaagca tcccggatcc ttccggctac aggtccgaca gttgctccaa
     3541 aaaagctttt gtctgttaga acatcttcga aacgatcgta agacaataaa acattttctg
     3601 attttccttc tttgtctggt gcgaagattt ggtgcaggcg ggcaccgtaa ttgagaagaa
     3661 cgacttctaa gtagtcgttc ttcaatgtga ttttctttat ttcagtctct ggaactggta
     3721 cgacggagat ctctggatta tccatggtca tgccactttt ctttcaagta atcgatcgta
     3781 agaaaagtcg tatcagggac aagcgggatc tcctctccaa ggtcttcagc acgtcccacg
     3841 ccaattggtt gagcgccact tgagaggatg gcttggatac cggcttgcgc gtcttcgatc
     3901 ccgatacatt cttctgcttt tagtccgaca gcttttgctg caaggaggaa gatatctggc
     3961 gcaggttttc cgtttgttgc ttctgccggg tcggcaatag catcaaagta aggtgtaaga
     4021 cccatttttt caagtaggaa tggcccgttt ttacttgcag aagcaagagc aatcttgatt
     4081 ttttcttctt ttaaagaatc cagtaaaggc acgaccccgg ggaagacatc ttttggttcg
     4141 atcgtctgga tcatctctaa ataataatcg ttttttcttt tcgctaattc tgcaaattct
     4201 tcctttgaaa aagagtgttc ttttccgcca taagctaaaa gcaaagagag tgagtcttct
     4261 cggctgacgc cttttagctg ttcgttgaat gtgtggtcga tcgtaatgcc gatttcctga
     4321 ccaagctttc gccaagcacg ataatggaat tcagcagtat cggtaatgac accgtctaaa
     4381 tcaaacaata cccctttaaa catttgcttc ctcctttctt agcgttattt ctagacgatc
     4441 cgctaaagaa taagactgtt catagacgta aatttctaga ggagaacctt ctaataactc
     4501 gaaagtaact tgttcatctg tgactgagat gaacaataaa cgtccgcgat aattgatatg
     4561 gaaagaataa gctttccaag tttttggcag aaatggtgcg aatctcaact gatcatgggc
     4621 agttttcatt tgagcaaatc cttggacaat cgacaaccag ctaccagtca tggaagtgat
     4681 gtgcaagccg tcttctgtgt cgttattgta attatccaaa tccaagcgag ctgttcgctg
     4741 gtacatttct acagctttgc tttccattcc taattctgct gctaaaatcg aatggatact
     4801 tggcgaaagg gaagactcat ggacagtcat tggttcatag aaatcaaagt ttttttgctt
     4861 ttcttctttt gtaaaagtat cattgaagaa ataaatcccc tgtagtacat ctgcctgctt
     4921 gatgaagcaa gatctaagga ttttgtccca agaccaatgc tgattcagag gaagatcgct
     4981 tgtgggaata tcggatacag gcatgagatc tttatctaag aatgtgtcat gctggacaaa
     5041 gattcctaat tcttcgtcaa ctgggaagta catgttctct gcgatatctt tccatttggc
     5101 tagttcttct tcgctgatag tgatagcagc ttctttttga taagttaaat aattttctcg
     5161 cgtgtaacgc aagacccaag ctgcgatcgt atttgtatac caattgttat tgatattgtt
     5221 ctcatattcg tttgggccgg tcacaccgtg gatcatgtat ttatttgctc gttttgaaaa
     5281 atggacacgg tctgcccaga agcgtgcgat ttctgctaaa acttccagtc cttcattttt
     5341 caaatattcc gtatcgccgg tgtaattcgt ataattgtag attgcatagg caatcgcgcc
     5401 atttcggtga atctcctcga atgtgatttc ccactcgtta tggcattcga caccagtgaa
     5461 ggtgaccata ggataaagcg cgccttttaa tccttgttgc tgagcgttgt ggattgcttg
     5521 cggcagttga ttatgccgat atttcagcag attcttagtt acttcaggtt tggctaaagc
     5581 aagataaaga gggacagcat acgcttctgt atcccagtaa gtggctccgc cgtatttttc
     5641 tcctgtgaat cctttggggc cgatattcaa tcgttcatct tcgccgtagt aagtagagaa
     5701 tagttggaac aaattgaatc gaataccttg ttgtgcttct tcgtctcctt cgatgaccac
     5761 atcggcaagc ttccatcgtt ctgcccaagc cgctgtttgc tcttcttttg cttggatata
     5821 attgtttgtc tggttcgtta attctgagac agctttttct gcttgctgcg cttctggaat
     5881 atctctacta gtaagaacga taatttcttt ttccactgac catgtctcac cttgagataa
     5941 ttctgcagac aagcaaccat gtaatgctaa agtatcttcg tgatagtcag ggatgactga
     6001 ttttccatta acgaaatggc gcattgctgc agtaacagta aattgttcaa tcccaaagtt
     6061 gtttggaata gttttagtcg tcaaatagcc gatttcttct atagttccac gatcaatctc
     6121 attccaaaaa tgttcatcat agttgctgtc ttcgttttga acatttccat ccaattttga
     6181 tacgagtttg actgttccgc taccttcaag catttctata gttaaataga tataagctga
     6241 ttcttttttg acaatgctca gaaaacgttc gaaggaaatg cgtactttat tagtagaagt
     6301 agtgattgtg aatgtacgag ataatacacc atttttcata tctaattccc agtaaaagtc
     6361 ttctggttcc aaagaagcca agtcgatcag ctgatcgttg atcgaaatat ctatcgcgat
     6421 aaagttcaag gcgttgatca cttttccaaa gtattctgga taaccatttt tccaccagcc
     6481 gacacgtgtc ttatcgggat accagacacc cgccaaataa gtaccttgat ggtggtcccc
     6541 tgagtaagtt tcttcaaagt tcccgcgcat ccccatataa ccgtttccaa tacttgttaa
     6601 agattcttgc agtcgaagat tttttttatc taattgtgtc gtgctgattt tccatggatc
     6661 aatagcaaat agtcgtttga tctgtttcat ttttctcctc ctaatgagct gttttatacg
     6721 ttcataataa acgcaaccga ttgcacaagt caatagacaa aagaaaatat ttcatagaaa
     6781 aaagcttaaa aaaataaatt tttaggagaa aattatagaa gggaacacac gtattatagg
     6841 ttttatagaa tggtatagac agaaaaataa aaaataaagc atttacaaaa aagaaaacgc
     6901 acgctataat acgtttaacg aaaccgattg cgtaaaggag ctaaacggaa tgaaaaagat
     6961 atttagtttt gagttttggc aaaaatttgg aaaggcttta atggttgtgg tagcagttat
     7021 gccggcagct gggttgatga tcagtatagg gaaatcaatt cccttgatca atcctgattg
     7081 gacgccgctt gtcacaacgg gcggagtaat tgaaaatatt ggttgggcaa ttattggtaa
     7141 tcttcatatt ttatttgctt tagcaatagg aggaagttgg gcaaaagaaa gagcaggcgg
     7201 agcatttgca gctgggatct catttatttt aatcaatcgg atcactgggg ctatctttgg
     7261 tgtcacaagt gacatgcttg cgaatgaaga tgcatttacc cacactctgt tcggtacgaa
     7321 gatcatggtt aaaggatttt ttacaagtgt attggaagca ccagctttga atatgggagt
     7381 attcgtaggg atcatcgctg gatttgtcgg ggcaatggct tataataagt actataatta
     7441 tagaaaattg ccggatgctt tgtcattttt caatggaaag cgctttgttc cgtttgttgt
     7501 tatcttatgg tcaacaatcg tggcattgat tcttgctgtg gtgtggccaa acgtacaggc
     7561 tggaatcaat aattttggtt tatggattgc agaatcacaa gaaagcgcac cgattctagc
     7621 accgttttta tttggaacat tagaacgttt actattgcca tttggattgc atcatatgct
     7681 gacgattcct atcaactata cacagcttgg cggatcgtat gagattttat caggcgcaca
     7741 ggcggggaca caagtatttg ggcaagatcc gttatggttg gcttgggcca ctgatttagt
     7801 gaatcttaaa ggtgcagggg atatgtcgca atatgagttt gtgttgcata actggacgcc
     7861 ggctcgtttc aaagtaggac aaatgattgg ttcttcaggt atcttgatgg gaatggcttt
     7921 tgcgatgtat cgtaatgtcg atcctgataa gaaagcaaga tataaatcaa tgtatttttc
     7981 agcagcgttg gctgtctttc taacaggtgt aacagaacca ttggagttca tgtttatgtt
     8041 tgctgctgtg ccattatatg tcatttattc agtgatccaa ggggctgcat ttgcgatggc
     8101 agatatcttg ccattgcggg tccattcatt tgggaatatc gaattgctga ctcggacacc
     8161 gttagctatc aaagcgggtc taggtggaga tcttatcaac ttcgtgttgt gtgtgatcgc
     8221 ttttggtgtt gttacgtatt tcttagcaaa tttcttgatc aaaaaattca actttgctac
     8281 accgggacgt aacggaaatt acgacaatga cagtgaagaa accgttgtat ctaacagcgg
     8341 aacaggaaca gcagatcagc aagtggtcca gatcattcat ttgctgggag gaaaagaaaa
     8401 tatcaaagat gtcgatgctt gtatgactcg gttacgcgta agtgtaaatg atcgagaaaa
     8461 agtagggact gaagaagcct ggaaacgagc aggggcgatg ggattgatcg tcaaagacaa
     8521 tggagtccaa gcagtttatg gaccaaaagc agatgtcttg aaatcagata tcgaagatct
     8581 gctgcaatca ggagcagaga ttccagagcc agaaatggtt tctacaggaa atggacaagc
     8641 aggtagtaag caatacttag gtatagaaca agaactagtt tccgcagctt ctggagaagt
     8701 gattccttta tctgaagtaa aagatccggt attctcacaa aaaatgatgg gtgacggctt
     8761 tgctgttatt ccaacatcaa gagaagttgt tgcgccgatc gctggaaaag tgacaagtat
     8821 tttccctagc aaacatgcaa ttgggctgga aacgaaagat ggtatcgaag ttttgatcca
     8881 tatgggaatc gatacagtcc aaatgaatca gccagctttt gagattgctg tcaaagaagg
     8941 ccaagaagta ggaacaggaa cgaaattagc tgagatggat cttgatgtga tccaaaacga
     9001 agaaaaagat ccaacgatca tgatcgtatt tacaaacgat aaagtagaag aagtagtgat
     9061 caagcaatta ggtacagtga cagctggtaa agtgatcggc tccattaaaa tgtaaggaga
     9121 ggttgtgaaa aagctgtcct gcatcaagtc ataagaacag ccaaacaaaa atagctcctc
     9181 ctatttttcg tttggttggg cttattaccg agaagcagca gtttgaatac tgtttagtgg
     9241 agaggtcgtg aaaaagctgc cctgcaccaa gtgataaaaa cagccaaaca aaaaatagct
     9301 cctggtccat tgagcttatt actgaggagt tagcaggaga acactatttg ctggagaggt
     9361 tgtgacaaaa attttgtcac aacccttttg tttcgaaatg aagacaagga gaaaaccaat
     9421 gaaattcatg acactcaaca cgcatagctg gcttgagcca gaaccagaga aaaaattgca
     9481 agaattagca gataagatcc tgttagaaga ttatgaagtg attgctttac aagaaatcaa
     9541 ccaattactg gaatctgaag aagtagaacc tgcgaagcta atgaagttct gtccggtaaa
     9601 gaatcaagta cctatccgta aagataattt tgcctaccgt ttagttcagc ttttaaagga
     9661 acacggaaaa gagtattttt ggagttggga aatgagccac atcggttatg ataaatatga
     9721 agaaggaaat gcactgctta cgaaaaaaac attggaaagt caggtcctta ccgtctccca
     9781 atttcaaaag aaagaagatt atcagacacg caagatcttg attgggaaaa caaagataga
     9841 tgatcaggac atttttgtct cgagctgcca cttttcttgg tggacagata aaaaaagtgg
     9901 cttttatttt gagtggaaaa acttggaaaa ctactttttg gaaactcgcg taccactttt
     9961 tttcctaggt gatttcaata atccagtaga ctctcaaggt tattatactg taagagaaag
    10021 ttgccttctt cttcaagatt cgtatgttgt cgcgaatgaa aaaggaaaag cagctactgt
    10081 ggaaaagaaa atagatggtt gggaacaaaa tacagaaaaa ttgcgtatag attttatttt
    10141 cgtccctgaa ggaatgcagg ttaaaaaata tcaacggatt tttgatggga tcgatagtcc
    10201 aatcatcagt gatcactacg gggtggaaat cgaattagat gtgaacgaat aaaaaatata
    10261 acatataaca taaaaaaact gattaaaata aaactctcca aacgattata ccgtttggag
    10321 agttttttga tcggatgtat ttatcccttt tgcctaagca cgtaaaagct tgtatctatg
    10381 ataaataaat aaacatagca aggtaaacca gccaatcaaa gtaagagaaa gaatgaaata
    10441 gaaatagatt ggcgtttgat aatgaagcgt gagctcgttg attccttttt gctgcttcac
    10501 gattggggtc ccgatatctg ttacttcata atcagtcaat gtttttccat tttgctgtag
    10561 cacagtccga tcgtagacga taacagggat atgaacagtt ttgtccccag tgtttttcca
    10621 cttgattgtc aaaagaccgc ctggatgtgt ttttataaaa gttgtttcgt tttctagtat
    10681 ttcttcgtta taccggtcgt atttattgtc ttttgtctcc ttatagattg gcagatagtc
    10741 aggtgtggtt ttttggaaaa cgaacaagct ggtagacata tctttgctga agaatgtttt
    10801 ccttgcttct tccggcgtat cgaatagata agtatgtcga ctgacaaatg tttcattttc
    10861 ccacttttcc agatgctggt ataagttctg gatcgtctgt gctgaaaaaa taagaatgcc
    10921 aaatatactt aaaagacgga accacttttg ttcagaccac tggttcagtg aaagggcaag
    10981 gtaaagtaga agcaatagcg taaatggcac gaaaaatcga aatggaaact ggatcaaact
    11041 aataaaaggc acattttttt cgatcaatgt cgtccatgga atcaagctag tagaaagaaa
    11101 aaagaaaaca agacttgtgt acaacacgat tttttggaat aaggtgttct tttgttgaaa
    11161 gaaaataaaa agcaaaaaac ctgataatat caatatagga aaggccttag ggtaatggag
    11221 ccaataactg ccatccagat ctatcgcctt ttgactcatt tctctgttaa caaagggagg
    11281 aagaatctta ttcccactgt aaacaatagc taatcctgcc caaatatttg ctgtcagaac
    11341 aaaataaagc aagaccgact taatcagttg aagcagtgct tttccttttt cagtctggtt
    11401 aaaaaagtaa taaagataaa aagggatata catcaaagct aacatgatcg aagacagtaa
    11461 atggatctgt gtcataagtc ccactgagac agcgactttg ataacaggga actttttatg
    11521 aaggacgaaa tcagcaatag ggatcataca taaaggataa aaacaagtcc cccagctagt
    11581 gaatccttgg ttgatagacc agtattgaat agaatacgta ctcatgaata aaacggctac
    11641 tggtacactt acccaatttc gaacattgac atatctcagt aaaatcagca tagaaaatcc
    11701 tgaaataaga taaagaatga aatttgaaag aatctgataa tgaaaccagc tacctgcaag
    11761 caacacgatc aatccttgta aataagcgaa aaatgggccg taaacggcat tcacgatcct
    11821 gccactttgc tggaatccat aaagggaagg aaaataatgg aaatccccat atttaatttg
    11881 ttgcgcggca tcatagaacc gattgtaatg gaatggggca tcagcaccca aaattagttt
    11941 atgtgtgaat aaatgaggca tgagaaatgc caaagcaatg aaaaaaattg ctaaaaatgg
    12001 gccatatttt ttcaattgtc gaactccttt gcaaacttta gataaattca tcatatatcc
    12061 tatgcgagag gtaggcaaga aattagaaaa ttcatgaaaa tatttatgaa ttttacaaga
    12121 aaaacataag tgaaagttct aaggagagag gatgcgacat aagttttgtt gcatctcctt
    12181 gttttgaaac agaatttttc ttaatactcg aaacaaagta gctttttcat gacctctcgg
    12241 taaacggtgt tcaatcagct gcttctcggt aataagctca ctagcctaga aaatatgaga
    12301 agctattttc tgactagcgc tcttattact caaagcataa cgcagttttc acaacctctt
    12361 ccttaaacgg tgttcaaaag cttgcatctg cggtaataag cccaacccaa caaaaaatat
    12421 gagtagctat ttttttgggc tgtacttatt acttgatgca ggacagcttt ttcacaacct
    12481 catcggcttt cattttctat ttttttcctg aacccatata ataaaagaaa gaacaaaaaa
    12541 acttgcaagg gaggacacat gtgaagcaga gtaagcaaaa acagtctcgt cgacttttgt
    12601 ttcgtttgtt tttattaata tgtatcgtcg tagggttact gatcgcttta tatccatttt
    12661 atgtggattc tttaaatagt tttattgatc aaaaacgtat cgaacaagta caaaaacgga
    12721 ccgcagctga aattgaagtg cagcgaaaga aaatggagga gaaaaaccaa cgattaactg
    12781 accaaggatt caatcctggt actgatcctt tcaatgaaaa gaacagaaat gaaagtacaa
    12841 catccagcca attagaggaa tggctgatcg gaagtatcaa tatacctaag atccaattaa
    12901 atatttcact ttatgatcgg ctcaatggta ggatccttga aaatggagca ggcgtcttgc
    12961 aaggaacctc tttcccgctt ggtggaaatt cgacgcattc agtgatctct gctcacagcg
    13021 gtttacctaa tcgacggtta tttaccgaat tagatcgttt agaaaacgga gacacgttta
    13081 ttttgactgt tttgggggag aaattggctt atcaagttaa aaatatacaa gtggtactgc
    13141 cagatgacac gtctgttcta acgatttcag aaggagaaga cttagttacc ttgcttacat
    13201 gtacgccgta tatgatcaac acgcatcgtt tgctagtgac aggacatcgg attccttata
    13261 acgaatcggt aaaaaaagaa gaaggaaaag gaaatcagga aagaaccatg cggcaatggt
    13321 ttattcttgc aggaacgata atagctgtag tcatactgtt agtgtttatc ggacgactaa
    13381 tctatcagta tagattaagt aaaaaagtgc ttgatttttc atttattatt agtgattcgt
    13441 cagggaaacc ggtaaatggt agttcattca ttttgaaaca taagaaaaaa acacttacta
    13501 gaaatggtgt gccgttttca gtacaaagcg accatcatgg gaaagtcaag ctggatcaat
    13561 tgcctggtgg aacttatcga atcgtttcag ctgatgatcc taaagttgct gtttcttttg
    13621 gtattagaaa agtaaaacaa gagaagatat acttttttga ggggcgaaaa cttgtaaaag
    13681 agcttcaaaa aaatggtttt tattttaaaa tcaatgaata agtaaggaga gaaaaaatga
    13741 tccgcacaac aacaaaattg tctgccaaag aactggaatc tgttctatcg atttggctgc
    13801 atgctaactt ggattctcat gaattcattc catcaactta ttgggagaat caagtagaat
    13861 ctgttaggaa agctttacca gatgcagtga tttacttagc agaaatagat caagaaatta
    13921 ttggttttgc tggggtgatt gatcagttta tcgcaggaat ctttgtgaaa agggaatacc
    13981 ggcaacaaag aatcggtacg caactaatga aaaaaataaa agaaaccaat aaaacactga
    14041 ctttgacagt ctatcaaaaa aatcaatcag ctattcattt ctatctttca caaggtttta
    14101 caattcaaac acagcaaaaa gatgaagcag taaatgagga ggaacttgtg atgaaatgga
    14161 atcaaaacgc tgatttttga tgaacagaat aacgaaataa tgctcccagc ctaatttttt
    14221 gctgggagca ttatttcatt ttgaagtcac taatttaact gtgtgaatat gcagttgtta
    14281 caatctttga taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa
    14341 aatatgagga actatttttc catttgtttc tctaatactc aggtcaaaac gctgatttca
    14401 caacctcttg ataaacggtg ttcaaacggc tgcttctcgg taataagccc actagcctag
    14461 aaaatatgaa aagctatttt ctaactagcg ttcttattac tcaaagcata acgctgattt
    14521 cacaacctct tgataaacgg tgttcaatca gctgaccctc ggtattagct caaaaaacgg
    14581 caaaacatga ggaactattt ttccgtttct ttctctaata ctcaggtcag aacgctgatt
    14641 tcacaacctc tctttcacaa ccttatttta ctcgtttata attttcatcg aagtattttc
    14701 cgctacggat atcatctggc attccatcgt atggttcttc gctaataaca tcttcattgt
    14761 ctatacctgc atcacccata taagtgatcg tagcaaattc aggaacaagt aattttggat
    14821 aagtttcata tttttcacga gctgcttcca tttctgcgat atgttcgttt tggaaagtaa
    14881 cagtgatttc tggatgttct tcaacccatt tagggaaaaa gatcattccg tgaagtttct
    14941 tttcatttgg cataaagtcc aatgccacgt ctgtccctgt tggctctgtc caagtgattt
    15001 tgaatacgcc gtccgtcaat ttaacgatat cagcttcttg gtcttttacc caacggcctt
    15061 tgaccattcc gccatggata cggtaatcaa cagtatggtc atttttggca taccattcat
    15121 attcccaacc attgtcatac gtatagataa agtgagttcc aataaaatct tccaattctt
    15181 taaattcttt catgtttaag catctcctta taaattaaaa catgtaataa actacatgtt
    15241 ttcgattact catttatgat agaatggatt taaagatttg tcaaggaggg aaaactgatg
    15301 gcaagaaaaa atacacttcg atatattttg ttagggttat taagtaagaa gaagatgaca
    15361 ggatatgaat tgaatcaatc gttcaaaaat gaaataggag aattttggca agcaaaacat
    15421 agtcagattt atcctgaact tgcaaaaatg gaagagcaag gaatcattca gcatcaagta
    15481 gagatcacag gtgaaaaatt ggaaaagaaa gtttatgaat taacagaaga agggaaggaa
    15541 caattggcag agtggattca tacacccacc aatgaactac cggttaatcg agacgaattt
    15601 gttctgaaat tgtatttcgt caaagacgtg aatgatccgg cattagtaga aattattcag
    15661 cagcagcgtg accttcatga agaaaaacga cttcatctat tagagcgaaa aaaaacgatc
    15721 tttcctactg aaaaagaaaa acatgaaaat tacggacact acctgatttt agcgcatgcg
    15781 atcaatcggg aaacagaata tgcaaattgg ctaacagatg tattagaaga aagtaaccga
    15841 aaaaaataaa aaaatatccg aacagtgatg gagaattcct ttctatatga aagaaacgca
    15901 gatcaccgtt cggatattct tatgttcaaa caggcctttt ttcaagtatt tatgtagcat
    15961 ctacttatta aaaagcttgg tacttaggag attagtggcg tttagagttc ttttaacaac
    16021 tgttcgtagt cagctttttc atcgacagga aggagcttgt aagttaattc gtctgtctcg
    16081 ttgtcatgaa tgatgtacat cttagcattc tcttctttga agttaccgat ttgtaaaatc
    16141 gtatagcgtt cgtcgatcaa ttcgatatct ttgattgctt ttgaaaaaac tttacggaca
    16201 tggtgcattt tcttttggcg gatttctgcc ttttctgcag cttttgacaa agtaaatccg
    16261 tcatctaaat attttttgat cagttctact tttatgactg taggtaaacg atattttcta
    16321 ggacaattcg catcagcttc gatcgaacga atgaatccct tttgttccca ataccttaat
    16381 tgacgtggag acacacctac gatatcactt aattcactga tgccaacaac caattgatca
    16441 ttttccaaca aacgtttaag ggaagcccca accatttttg tcactccttt tgtcctcttg
    16501 cttcccttaa ttatatccgt attaacttat gtgtcaagta ggttgacaaa tagcgaattt
    16561 aggactaaag tattctagta gtttcagaaa aaattcagaa agaaggagaa atatgagtaa
    16621 caaccaaccc gtagatattt acggaaaacc atataatcgg acacttttag ttgttgtctt
    16681 attaattggt acattttgta ccgttttgaa tcagacctta ttgacgacag cttttcctac
    16741 attgatgaaa gctttcgata tttcagcgtc tgatgtgcaa tggttaacga ctggtttctt
    16801 gctagtcaac gggatcatga tcccaataac agcatggctg atcaataaat tcagttcaag
    16861 aaatttatat ctttctgcca tgacgatctt tttgatcgga acgattactt gctttacagc
    16921 acctaatttt agtacattac taatcggtcg tttgatccaa gcttgcggtg tgggagtatc
    16981 gatgccatta ttgcaaaata tcatgctatc tattttcccg ccagaaaaaa gaggatcagc
    17041 aatggggatg tcagggatcg ttattggact tgctcctgct ttaggcccta cattatctgg
    17101 ttatatcatt gataactacc attggcgtga cttgtttggt atggtactgc caatcgttgt
    17161 tcttgtcttg gttttagcat tcttcctaat gaaaagtgtt attccattgt caaatcctag
    17221 cattgatatt ttatccgcta ttttatcaac gattggattc ggtagtttac tttacggatt
    17281 ttctagtgta ggagatgacg gctggggaag cttgaaagta attggtttct tagttgttgg
    17341 tgtgattttc atcgccttgt tctcatggcg tcaattacat ttggaacatc cattcttgga
    17401 acttcgtgta ttcaaatcat ctacattcac gattgcagct gttttagctg gtgtaacaaa
    17461 tatggcgatg gtaggggcag aaatggtcgt accattgtat attcaaaata ttcgtggaga
    17521 atcagcattc cattctggct tgatgttgtt gccgggtgca ttgatcatgg gggctatgat
    17581 gcctgtgacg ggtgcgattt tcgataaata cggcgcgaaa cgtttagcca tcacagggat
    17641 gttcattttg acagcggcaa ctgcaccatt tgctttcttg acaaaaacga ctccagtttt
    17701 atatatcgtg atcctttatg cgatccgtat gtttgggatc tccatggtca tgatgccggt
    17761 aacgacttct ggtatgaatg cattgccaaa taacttgatc agtcatggga cagcggtaaa
    17821 taatacattc cgtcaaatcg caagctcgat tggtacagct attttgatca gtgtgttgac
    17881 gaatgtgaca aaagcaaata tcccaagcaa atctgtattg gataatacgc cattagctta
    17941 taaagatcag gcaatcaatg ccacactgtc aggttaccat gccgcgttta tcgtagcgat
    18001 catctttggg attcttggct ttattattgc ctttttattg aagaaaaaag aacctgttct
    18061 aatgaaagcg ggggataatg catgattatt ggagttttga ttgtcagctt gcttgctttt
    18121 gctttaacga acgtgttcgc taaaaaaaca tggcaaacct ttttatcttt gattttcgga
    18181 ctaatcttcg tcgcttcact aagtttgatc gtcgctaatt tgtccaatca ctttggaatg
    18241 gaaaaagtaa cggaaacaaa aacagaaaaa attgtttcca gtgctgattc ccaaggagca
    18301 gatatgcttt tgtataaagc tttagggaat ggaaaagaaa aagtgtatct ttaccgaaca
    18361 aatgaaaaac aagaaaaacc aaaagcaact ggtacggata acgaaacaaa taaagtagaa
    18421 aagacagacg gcgatgctga aaaagtgacg aaaactactt attgggaata caaaaacgac
    18481 atgtataaat tctggttcaa tattgctgat aacaatcacg aatatgacag ccgagtgaat
    18541 acattcaaaa tcccagagac atgggtagaa ttaagtacgg accaagcagc caagttagct
    18601 gaattagtga agaaacagca aagtacgatg gaaagtgaag caaaagctta tgttcaagac
    18661 ggtatggtaa aagcaatgac tgaaaatcca aaaatgagca aagcagagca agaacaacgt
    18721 acgaaagcct tagctgctga attccaacaa caagcattcg caaaattagt gaaagaagca
    18781 aaaggcgaat aatattttga acaccatgta ggaggttgtg aaaaagctgc tctgcatcaa
    18841 gcagtaagaa caatcagata aaaatagcac tccatatttt tcatctgatt gggcttagtg
    18901 ccgtagatgc aagcttttga acaccgttta aggaagaggt tgtgagcctg ccgtttaact
    18961 ctgagtcaca aggagcaatt tcaaaaaaca gcttctcatg tttgttgact attgtgactt
    19021 gtgaccgagg agttggcagg agaacaccgt ttattcgaaa aaaggaactg cgacaagact
    19081 tttgtcacag ttccttcttt tttttgctat gctatactag atgtaaaaaa taggagaaat
    19141 aaaatgaggg aaatttattc ttttgaatca aaaatctatg cttccgaagt cggcaagggc
    19201 ggggcatata ttatttttcc gtatgatata agaaaagaat tcggtgctgg aagagttaaa
    19261 gtccaagcaa cttttgacaa tgtgccgtat gaaggcagta tcgtgaatat gggcgtgaaa
    19321 aatccagatg gttcagtctg ctacatcctt ggactacgaa aagatattcg taaaaacatc
    19381 ggaaaagaaa tcggtgatat tgtagcagtt acagtgaagc aaaaataaaa gaggttgtga
    19441 caaaagacgt gtcacaacct cttgataaac ggtgttcaaa agccagtttc tcggtagtaa
    19501 gtcaaattta tgcaaaaatg tggaaaccca tgtttacaaa atttttctta ctactcgaaa
    19561 cgaagcggct ttatcacaac ctcttgataa acggcgttca atcagctgtc cctcggtatt
    19621 agctcaaaaa cggcaaaata tgagaagcta tttttccatt tttttctctc atactcaggt
    19681 cataacgctg atttcacaac ctcttctttc ataatggttt ttcaccatct ttataataaa
    19741 ctggttcttt gatatggaaa tctatttttt ccaaccaatc taaaatcttg taacctaact
    19801 cttctgacat cggaaaagag gcgttgattt gtgcattgga gatatggtca acatggatac
    19861 cggaagtgat cgtacaactt cccggaacgg cagttttgat gatcacagct attttttcgg
    19921 ctaagacatc gtctttatgg aaccgaccat cgtggctagg gaaacgtaca gtttgcatct
    19981 ctgtatcacg agaaaatgta gtgactgttc cgatatgtgg tgtatctccg cctgttaaag
    20041 tgatcaataa gtctttaccg attactttaa cagcagcttg gatcgtgaaa cctagtttgg
    20101 ttacttcaac tatcgtttct ttttccatat taatcaccct gccaacgttt tgaatgctca
    20161 tttacaattt caaattgatc caaaagtttc attgtatggt gattaacaag atcttggatc
    20221 gtttgaggct gattataaaa agcaggaatt ggtggtatga tttgcacacc tagtcgtgct
    20281 aatttagtca agttttccaa gtgaatggca tttaatggcg tttcacgagg aacaatgact
    20341 aactttcgtt gctccttcat tgttacatca gcagcacgtg caatcaggtt gtcgcctaaa
    20401 ccaacagaga tacctgcgac tgttttcata cttgccggta cgatgatcat tccatcggtc
    20461 aaaaatgatc cgctggcgac agcagcacct aaatctttgt ttgaataatg gtaatcaaac
    20521 aggctttcga attcagttag tgataagtcg gattccagct ttaagttctg ttttgcccat
    20581 ggactgatga ttccgtgtgt ttctatcatc ggatattctt ttagtttctt cactaggttg
    20641 atggcataaa tggtgcctga agcgccactt acaccaatca cgattttttt cttccgttgt
    20701 gccaattgtt ccattttccg cactcctttt tatgatgtca aaacagttgc agatcattca
    20761 ttatttcaaa tatttttccc aatcttctac ttcttggaat tttgcacgta caaaatgttc
    20821 tttcatatcg aaaggaactg taccgtcaaa gatagttttt gcacttatcc cacggaaacg
    20881 aatagagcca ggattatatt ctggtaattc tgatgggtcc aatggatggt tcctcattcc
    20941 tgggatcacg atgatatctt tatctccttg gaaacgagtg ttgaaagtcc aaactacatc
    21001 gttcatgtcg aaaatatcaa catcttcatc gactaaaatg actgtcttca attctttgaa
    21061 ggctgataaa gcaagaatag ctgcttgacg ctgaatacct tcatccgctt cgttttcttt
    21121 acggatttgc atgatggtca tcaatttacc accacctgca ggaggattgt agacatttac
    21181 tacttttcct ggaatagctt tatcgaccaa ggcaagaata cttgcttctg taggaatacc
    21241 ggccatagat acgtgttctt cactgggacc aatcgttgtt tgcatgattg gattgtcttt
    21301 tcggtgagta actgctttga ctttcactac ttgtacagct ggattagcat ccccagtata
    21361 gccaggaaat tctggcattg cttttcctga gttcgtgttg atatcttctt gcattgtttc
    21421 atttggcatg atttctgctt caatgatgaa ttcagcacga gcaataccca cttcatcgac
    21481 tgctatacca tcaacgattt gaataggttc gttacgcaaa gctcctgcac accatagttc
    21541 attgtagcca agtggagtgg taggtggttc gaaagtcgtg ccaatggcaa ttgctggatc
    21601 taaaccaata ttgatagtga taggcattgg tttattcaag gcttcgaatt gtttttggaa
    21661 gtgaccaatg tggcgtccgc caggcatgat gtacataccg atcgtatctt tatcttctag
    21721 aaccatacga tggatcgtta catcgctcat tgttttttct ggatctgatc ctaagactac
    21781 acccattgtg atgtatggac cagcatcttc aggagtattt gtaggtgcag gcaaaatgtt
    21841 gcgaatatcg aagtctgcat cggtagctag atgaacgact tcttgtgctg gagcgtctgc
    21901 tttgtctact ttcacaggtt tgattggatt ttctacagcg tctttcaaga aacgaccaag
    21961 tgttcgataa tcatggtgca aaatttcacc tacacgttta cgactagcca ttgttccgat
    22021 gttcacacgt gtgccgggga aacctttgat attgttgaaa gtcatagctg gtccttcttg
    22081 agtcggacgt tttactgtac cgccagcacc gatataacgg taaacaccag ataattctgc
    22141 ttcaggatcg atttcaatat ctgtttcgtg atattgacct ggaagtgttt ttagttcttc
    22201 gatgactttt cttaaatcat acggttgatc tgtcatgaga gattcctcct tagttgtctt
    22261 tacctatcta tagtaaaagg tgaaaaagag gaaaacaatt caacttgttc ggtaaagtat
    22321 tctacaatgg aatggatgcg tttttttgat aatagaataa actatgatat acttatcact
    22381 aaaagaaagc gcatacttag tgttggagga aggaaagtga aaaaaatgga ggagtcattt
    22441 cctaaagcag taaaagtgga aaatatagcg aatattttga aagttacatt tgaaaacgga
    22501 gaagtaaaat acgtgaaatc tcattggaca gaagagataa ccgatgcctt gcaatttgga
    22561 aaaaaaggaa gaggaaaaag aaaaaatctt ctcgcacttt ctcgtaatat gtggattggg
    22621 actgaagtaa cgattgaagc agatggaaca gtattcataa atggaaaaga caggtatacg
    22681 ccagaagagt tgtggtacaa aggaaagaaa agtataccag aattataaaa aataattaaa
    22741 aaaaacagcg cgaaacaagg aacatattac ttcctcgttt cttgctgttt tctactattt
    22801 cagcgctctt atgactcaaa tctaaatgtg gttgtcacaa ccttattctg cacgcaaagc
    22861 gatagcggcg tcttttttcg ctgccattcg tgcaggaaga tgaccgccaa gcatcgtcaa
    22921 tatagtagag acgatcacta gaataatcgc atggacagga tttagttgag caacattttt
    22981 tagatccgtc atgttgtata agatgctatt gatagggaac gtagctagcc atgcaataaa
    23041 cacacctaat atcccagaag aaatacctaa aatacacgtt tctgcgtcaa atacgcgagt
    23101 gatgtctttt ttacgtgcac ctaaagcttt tagtacaccg atttcttttg tccgttcaat
    23161 cacagatgta taagtaatga tactgatcat gatcatactt gttactaaag agatccctgc
    23221 aaaagcaata aggacataag tgatagcatc catcaatccg ccagtcagtt cagtcatcgt
    23281 tccagctaaa tcagtataaa tgattttatc ttcatctgat ttgcctttat tgtaatcatc
    23341 tagataatcc aagatctttt ctttgtcttc aaaattgttc ggataaatca tgatacttga
    23401 aggcaagctg tctccaccta aataactaag caatgtttgt ttggcatttt cgtcaacttt
    23461 ttcagtagtt aagacattta caccactgtc tctttgagct ttgacgattt ctgattcttt
    23521 gttttcgttg acgatttgag tcgttaattg atcgctataa gcgattcctg gagataagag
    23581 attcattgta gaagaagatt tcacgcgtag gatccccgag atcttcaatt catcagaagc
    23641 attctgatac atcgcatcat aatctgtatt agggataaaa ttcccagttg gaagttttgt
    23701 atagtaagta ttgttgttta ctaatttgaa tgttgtacca acgatatcat caaaatcaag
    23761 tttttcgtct tctttcacat caaatccaag attcttcaat gcgttgatat tagtattatt
    23821 attgccgtct acgatcagca cgacatctgt tgctgaggct ggataacttc cggcaagtaa
    23881 agaataattg tcttttaaaa agttttcttt gctagtgtca agctgtgtag ggaaacttga
    23941 cactcccaca cctgtcattg ctgacatcgt actagataaa gaaagagatt ccgtatcagg
    24001 attttgattc gagaagctga caggctgtac tttgccattt acatcacgta aaagattgat
    24061 tcctgtagta cgggtaaatc cgatattatt acttaagtta ggatcgatgt ctgttacgta
    24121 atcgacgtat gtttgatcaa tcttattcgt gtgctgtgct ttatcttctt cgctgacttt
    24181 tgcagtaatc gttttgctgt ctggataatc cgctttgctt gcacccaatc cggcatcgtc
    24241 acgagtctgg ttagtcgtta ccttagaaat agtaatcgga aatttcgcca tcgtttcagc
    24301 ttgcgtgtta tcgatttgtt tttggaatcc agaagaaagg gacagaacga tcgcgattcc
    24361 gatgatccca atactggaag caaaggaggt caagaaagta cgtccttttt ttgttcggat
    24421 attgttgaag gaaagcttta acgctgtcca aaaactcatc tttgttctgc gtaagttaaa
    24481 ttgatcatct tttggtcgtt cgatgtgagg atgggaatct gttaagatct taccatcaga
    24541 aaattcaatg attcgatctg cgtattgatg ggccagttca ggattatgtg tgaccatgat
    24601 cactaatttt tctttcgata actcttggat caattccatg atctggatac ttgtttctgt
    24661 atctaacgct ccggttggtt catcgcacaa aaggatatct gggtcattgg ctagtgctcg
    24721 agcgatggcc actcgctgca tttgtccacc agataactga tttggctttt tatgcatatg
    24781 atttgtcaag ccgactcggt gcaatgcatc ttctgcccgt tttcgttttt cgtctttaga
    24841 aacaccactt aatgtcatcc caagttcaac gttttcaata atgcctagat gaccaatcaa
    24901 gttgtaactt tgaaaaatga aaccgataga gttgtttcgg taggcatccc agtcactgtc
    24961 cttaaagtct ttagtagact ttccgttgat taccatatca ccggaatcat aattatctag
    25021 tccaccaatc acattcagca tagtcgtttt accagaacca ctaggaccta aaatcgctac
    25081 gaattctttt tgtctgaaag cgacagacac accatccaat gctttggtgg tggtttcgcc
    25141 gactttataa tattttttta tatcttttaa ttgaagcata atcacccttc tcccgtattg
    25201 aaatattcgg tatactaata agtatatcag aacaatgatc gtagtatacg aaataaatgt
    25261 taactgaaga tgaactacaa gaaaaaatct agaaattttt caaaaaacag agggagatca
    25321 atgaatcgta ttttagtagt agaagatgat ccgcaattac agttgcttta ccgttctgtg
    25381 ttggaacgag cgggcttttc agtcatcacc gcattgaatg gagaggatgc gctgaaaaaa
    25441 ctagaagcga cacgtataga attaatcatt acagatatca tgatgccgaa aatggatggc
    25501 tatgacttgc tagactcatt acgtagcacc agatttgaca cacctgttct aatgattacg
    25561 gcaaaggccg attttgagga taagaaacgc gggttcaaat taggagcaga tgattatatg
    25621 acaaaaccca tcgatgtcaa tgagatgatc ctacgtgtgg aagcattgct tcgacgttca
    25681 aagatcaatt acagcagtag cttgataatc ggacaaacaa aattagagct agatgcttat
    25741 acagtgttac aagatcagca ttcgttgatt ctgcctcaaa aagaatttct gcttctgtat
    25801 aaattactgt cttatcccaa caagatcttc actcgccaac agttgatgga tgatatttgg
    25861 ggattagata cgaatacaga agaacgaacg atcgatgtac atatcaaacg tttaaggacc
    25921 cgttttgaaa agacggaaga ttttcaaatc atcacagtac ggggactagg ctataaggcg
    25981 gttatttaaa gatgaaaaaa aagctatttt cacaattatg gatctatttt gctagtattg
    26041 tcttcatttc gatcttagtg acactgctgt gttttctcgg ttttattttc ttattgtctc
    26101 gacattctat ctcgcctgct gaatcggctg gaaaaccaac gttatacccg ttattcgtct
    26161 ttgcggggtt cagtatggtc gtgggtacag gaatatcgat ttttgttggg cggcgtatcc
    26221 tgcatccaat cagtgcgcta gggacaaata tgagtctggt agcaacggga gatttttcga
    26281 ttcgaatgga tgaacagcag aaagtagcag aagtacagca actgtataaa gatttcaacg
    26341 ttatggtcca agaactcaat agtatcgaga cactgaggaa tgactttgtg tccagtgtat
    26401 cccatgaatt caaaacacca ctagcaacaa tccaaggata tgttcaattg ttacaagccc
    26461 caaatctctc tgacgaagaa cgccaaatat ttttatatcg gattatcgaa agtatcacgc
    26521 agctttcaca attaacagag aacatcttaa aattgaacaa actggaaaac cagcgtatcc
    26581 aactggaaaa gaaagagtat cgattagatg aacaaatcag agaagtaatc gttttttttc
    26641 agcctaaatg ggagaaagaa cagctagaat tggatatcga acttgctgca gtaaattaca
    26701 caggcaatga agagtttttg taccaagtgt ggctgaatat catggataac gccataaagt
    26761 acaatcaaat caatggacag attcatatca aactatttga gacagccaca gagattgtac
    26821 tggaagtgac cgattcaggt gtaggaatga atgaagagac cagagatcga atgtttgaaa
    26881 aattttatca aggagataca agtcgtcaaa tttctgggaa tgggctagga ctttcactgg
    26941 ttaaaaaaat tctagaactg catgatggac gtattgatta tagcagtatc gaaggagtag
    27001 gaacgacagc aatgatacgg ttaagtaaac aataggaaaa agaataaaac ccctaaaaat
    27061 tctattgaag gtttttaggg gtttttagtc gtttttttgt gattagggaa atgttcttac
    27121 ggttcttttg gcataaaaat cgctgctttc ttattgaact acgagaaatg ttagaggtgt
    27181 cattgaaaca aggacatgat gcaagaaaga gagcgaaagt catgcgtcgc tctctttttt
    27241 tgggtggata gatggacaga aaatgtaggg cttagttttc ttcttgattt aaatactccc
    27301 aaaatgtatc tgaagccaaa gaatgctcac cgactttacg agtaaatgca agataactct
    27361 ctgttgttgg agaaataggg agaatcacag tattttcttt taatagattc ttgactgttt
    27421 tttccataac aatagcaatc cccatgtcat ttgcaatcat attgatgatc aagtcgattc
    27481 ttgctccttt ataagagatt tttggttcaa atccagcttc gcgacacaga tctagtacag
    27541 gttgatacaa gttcgtagtg gggccaagga gcaaaaagtt ctcctttttc agttcgctta
    27601 gatccaattt ctttttacta gctaaaggat gatttttagg tagaactgct acaaaatcgt
    27661 ctgtttcagt aggcaaccac tcaatcgaac ttggtggggc ctggaaactt ctagcaaagt
    27721 ggatcgtgtc actatgttca ttggcgtcat tgtaagttaa ttcgacactt tccacttctt
    27781 tcaactggac tgtaaattca ggatggcgtt tcaaaaactc ggtgattttg gaaaaacctt
    27841 tataattgat cattgtcggt atcgttaaga tatttaatga aagattgttg tctttcgtat
    27901 aggtttcaag cacttcttgc atagcatggt attgttctac gacatttttt acatatggga
    27961 gcaataagct tccagcttcg gtcaattcga tttttctaag ggcgcgttcg aataatttga
    28021 cgtctaattc tgtttctaac gaaagaatct gtttagaaat atttccttgg gtggtgaatt
    28081 gtcgatcagc agttttggtg aaattcattg tttcggctaa atcaagaaaa acttcgaatt
    28141 tatggatatc catcatattc ctcctactta ttccaataaa gaatacttta acacaaaaaa
    28201 tgaattggtg taatcttctc tgtctgttac aatctttctt gcagcgaaag caataattac
    28261 agaaattttt ctgatttttt tcgcttcgta gaaaaagaga ggagtttttt gatgccaact
    28321 ggagttttga tcaatgtagg ttccgttttg tttggcggac taattggcgg attagtagga
    28381 aataaattaa gtgaacattt taaagcacag ctgacgatgg tttttggtgt gtgttcgatg
    28441 gggatgggaa tctattccat tgcgccgatg aaaaatatgc cggctgttat ttttgcttta
    28501 gtgataggaa cagcgattgg tttgattgtt catttaggta atgggataaa taagggggct
    28561 gcgctgatgc aagtacctat ttctaaaatc ttccctagtg aaaagcttgg tatgacccac
    28621 gatgaattta tcagcacatt agtgacggtc attgttctat tttgtgcaag tggtacgggg
    28681 atctatggaa gtttagattc tgggatgaca ggagacagta cgattttgat ttctaaatct
    28741 gtccttgatt ttttcacagc agctattttt gcgtgtaatt tagggtatgt cgtttctgtg
    28801 atagcaattc cccaattcat tattttttat attttgttct tattggcaaa atttatttat
    28861 ccattgacta caccagacat gatcttagat tttaaatctt gcggcggatt cttgatggtc
    28921 gctaccggtt ttagaatgat caacgtgaaa atgttcccag tagctgacat gatacctgca
    28981 atgatcgtta tcatgccact gagctggatg tggacaaatt ggattatgcc actgttataa
    29041 taaaaatcaa agagaagcca ttttttgctg actaaaaagg atcaaatctt ttagtcagtt
    29101 tttttgtatt tgacaaactg attttgaaac tatattatat gttgtataat atagattgaa
    29161 ataaaatatt acacttgaga atagaaggtg acgtaatgca catccagatt ccaactgttc
    29221 ttcttgatgg tactgtgcta gcagcattaa gcaaggaaga tatgtatggg tatgccttaa
    29281 caaaaatcgt acaagaaagt ctctctgtca gtgaatctac actatatccg gttttgagaa
    29341 gattgaaaaa agaaggatat cttgagacct atgatgaacc ttttgaaggc agaaaccgtc
    29401 gatattactc gttgacacca atgggaagtc gtcatttaga agaaattatt gatgaatgga
    29461 ttgtttttcg agattcttta gaccggttat tggaggagag cacaaatgaa tgaatatttg
    29521 aatgaagttg tggatcatct tcaagaaatt cctgaagacg atcgttttga tttgatccag
    29581 tattatgagg aatatttttt agattctgga aaaacattag atcagatcat tgatgaatat
    29641 ggtacaccaa agcagtttgc cttaaaatta aaaatcagtt acttttcaga agaagaacaa
    29701 gcagaaaacg agttagtgaa aaatccaaaa agacaaattc gcctgatttg gttaatcatt
    29761 atcggtttat ttgcttctcc tgtcctcatt ccactagcac tggggtttat attggttatt
    29821 gggggactat tggttgcttt actagcgctc atttttagta tctatgtttt atgtatcagt
    29881 atcttaggtg ttggcctatt catgatcatc tcaggaatca gtgtgtttgg acaatcgatt
    29941 ctgagtggat tattctttat cggtgtcggt ctgttcgcca caggaagcgc agtatttatt
    30001 tcgccactgt tgctgaaagg aacaaaaggg cttttttatg tcatgatgaa ctttgttaaa
    30061 tggatgggac gacgttttat tacaaaaaga gatctgcatt cagcgggcgt ttgaaggagg
    30121 acacataaat tgagattgaa acattttttg attaccggta ttggtctgat gcttactggt
    30181 ggcctcctag caggtgcaac ttatacatta ggcgctcaaa agagtctgac ttgggataat
    30241 ggtcctcggt tgatcgatat ggttactgag acaaaaaaaa tcaaggatgc aaacaaaatc
    30301 gtcatccatg cagaaaatca aacagtttcg gtcatacgcg gattggattt tgagataaaa
    30361 acgacttatg ataagacaga aaagccagaa ataaaggaga aaaatggcgt gttgactgtg
    30421 aatgcagtca aaaaatcaac aggtgcaatc attagtttag aagacacaag tgcacaaatc
    30481 actattgttg tccctgcaga tcatgaatta tctgaattga caatcgaagg gaataatagt
    30541 gcaattgata tcaacgaagt atcaatcaaa aaagtgaata ctaagacaca tgatggctgg
    30601 gtatcgttca atgaatttac aggaggaaca ataactgcga aagatgaatt aggctcactt
    30661 cgattagatg aggccaatgt ggataacttg atcgtcacag gtgaaaacag caacttccat
    30721 ctagaagaca gtttgatcag caaagaagga aaagtcatcc taaacggtgg caatttatct
    30781 ttgcatgaga tggaaaacag tggctatact atccaaacgt ctggtgaatc ttatattgaa
    30841 aaagactacc agccaataac aaatactttg ttagaacaag gacagaaaaa gctaaagatc
    30901 actgctaaag acacatcgat caatattacg acggatcaag aggacaatga aacagattga
    30961 tcctgtactc aactggatat tttaagaaaa aacagcaaag atccttccaa tctttgctgt
    31021 ttttcatcgc ttaacgcaca taactatagt aaaataagaa agaaaatatc taaaaagaaa
    31081 acagggtgaa agagtatatg aaggtagaag aaggtcaaag agaaaagtta aaaacagaaa
    31141 tggaaagatt acatacttat atcactcaac taagccaaac cttctatgat ccagacaaag
    31201 aaaaagtgat ggttaattac ccgaacaatt cagaaggtcg ccaattagag caagtgtacc
    31261 atgaagtttt caaacattta ttgacggtga agaaagagct ggattattat tctttaccga
    31321 ttatcgatac aggaatattg aagtatgatg ggaagaagga acgatttatc tttaaatctg
    31381 ttcgggaaga tttgcctctt tcagcaggga tggatctaga ggtcttggta gaagactatt
    31441 ttacagaaga aaagcactgg gttcgaacaa aattggatta tttaccgcag gcagccggag
    31501 ggacacaggc aagcggttgg tacatcactg aagacaaaga gttagaacta gaaggtgtaa
    31561 tggcgcgtat tcgaaaaaaa aattaaaaaa gtaacattag atatttattg aaggataaag
    31621 gagcgcagga agtagcatga gagaaaaaag agcattttat atcaatggtt atgcagggat
    31681 tgtcggattg gtcgtattag ctttagttgg attgtttttc ttctatttag gtatgtggca
    31741 agcgaaagtt tgggcacttt ttttaagtat ttttctttgg ttgatcacgt tattgttgtt
    31801 aagttcggca actgtagtca gtcctaatca agcaaaagta attttgtttt ttggacaata
    31861 tttaggtacg attcgagaaa atggcttttt ccttacgata cctttggcac aaaaaatgac
    31921 tgtttcgttg aaagttcgga atttcaatag ttctgtttta aaagtcaatg atttggatgg
    31981 aaaccccatc gaaatctcag cagtagtagt ctttaaagtc gttgatacag caaaggcatt
    32041 attcgatgta gcgtattatc aagattttgt agaaatccaa agtgagacag ccattcggca
    32101 tatcgctagc caatacccgt atgatacatt caatgagaat gatttgacgc ttcgaggaaa
    32161 cacgacggca gtgtctgacg agttgcaaaa agagctgcaa gagcgtttag cagtagcagg
    32221 tgtcgaagta atcgaaacac gcttgaacca tttagcctat gcaacagaaa tcgctagtgc
    32281 catgctccaa cgtcaacaag caaaagccat tttgtctgct cgacaaacca ttgttgaagg
    32341 agctgtcaca atcactcaaa tggccttaga gcaaatcgaa gatggacaag aaatcaattt
    32401 caccgatgat cggaaagtcc aattgatcaa taatttactt gtctcaatca ttacagacaa
    32461 aggaacgcaa cctgttatca atacaggcga catgaaagac cgtaagtgac atactttttg
    32521 taagatagga agaaggagtt taggacggat tattgtcttg aactcttttt ttagttgttt
    32581 taaagaaaat gacaaaattg aaagaagaat gatagttgat tcgaaggcag aattgttcgc
    32641 ttttttctat aatcagtata taaagtaaga gagaagggga aaaagtgaaa aaacttctga
    32701 tcggtctact tgttttcatc gttgtggtac ttgcaggggt gaaaatcgca gattacgtag
    32761 ttatgggtgg agaagaatac tatatacaaa ttacgacaga tggtacaaaa acagtttcaa
    32821 aatcagactc tggacaagaa acagtcaact atagatatat cctgcctggc tatacgaaag
    32881 agggtaagga aaaagaactg gacttcaagg gacaattgac tcgaccgctt cgtaaaggag
    32941 catatttaaa aatcacctgg aacaaaaata aaggtgtcac ttcgtatgaa gaagtcgaaa
    33001 aaaaagacgt gccgaaaaca gcactggaaa aactaattaa agggtaggga aagaaatgaa
    33061 caaaatagtc gaagtacaga atgtaacaaa agtatacgga aaaaacaatg agaaaaagac
    33121 gcaagcatta agcggcatca gcttcgatgt agaaaaaggc gaatttattg ggatcatggg
    33181 cgcttctggt tctggtaagt cgacactttt gaatatttta tccacattag ataaaccaac
    33241 agatgggcat atccgaatca atcaaaaaga tgtgaccaca ttaaaaggaa atcaactagc
    33301 agattttcgt gcgaatgaga ttggctttat tttccaagat ttcaatttat tagaaagctt
    33361 gacagcacaa gaaaatatcg ctgttcctct ttctttacaa ggcgtcagac caaaagaaat
    33421 caagcaacgt gtccaaaaaa ttgcagaacg tttatccatc tctcatattt tggaaagcta
    33481 tccttctgag atttccggtg gacaaaaaca acgggtcgcc gccgcacgtg cattgatcac
    33541 acaaccaacg attctattag gggatgagcc tacaggtgcg ctggattcca aaagtgcccg
    33601 ggatctttta gatacgatgg acgaattgaa tacaaaagat catgtatcga ttcttcttgt
    33661 gacgcatgat ccgttttctg caagttattg ccaacgtatt ttattcatca aggatggcgg
    33721 tatccatcaa gaagtgaaac gtggagatca aagccgtgat tccttctatc gagaaatact
    33781 atctattctt ggaaacttgg aacagtaggg ggagattgac tatgctttgg aaattatcac
    33841 ttactgggat caagagccgt ttaagagact acttggtgtt attctcagga ttagttatgg
    33901 catctgctat tttttacatg tttgaatcaa tggcaagcaa cgaagctttt ttgaaaagta
    33961 atacgatcgt tgcggctaca gttatcattt tccgattcgg ttctgtttta ctagggatca
    34021 tcacattcgt ttatatttta tatgcaaatt cctttttgat gacgatgcgg caaaaagact
    34081 atgcaatgtt tatgatgctg ggagcaaaag gcagaaaaat cgcacagatg attttttctg
    34141 aaacattctt agtagggatc gcagctactt tagtgggttc agctgtcggt gtaggattga
    34201 caagtatcgt ccaccgatta ttagtggatc agttagatct caatatttcg cattttacac
    34261 cttttagtat tcacgggttg ttgatcactg ttttgttttt tgctgttttg tttttattag
    34321 ctgctgttgt caatgctttt tcgattgtca aaaaaccgat tttagcattg attcgtgcgg
    34381 atcagacacc aacaagaatc aagcagcata aattcttgtt tttccttgaa gtagtactgg
    34441 gaattgcttt tctaggctgc ggttactata tgatgaaaca cgtggggacc tatcaagtct
    34501 ttggtatagg ggtagcctta gttacgatcg tattaggaac ttatttcatt ttccattctg
    34561 tgatcatttt ctttttatca ttactaaaga aatcagaaca gatttcattg aaaaaattga
    34621 acaatttcac attgtcacag ttaaactttc gtattcgtga atatacacaa atgctctcaa
    34681 tggtcgctat gctgtttgcc ttggcactgg gcgctttgac ggtaggatta ggttttaaaa
    34741 atgaaattgc agacttgaca gaaaacaatt ctggatatga tctagtgatg aataatcctc
    34801 gggcagaaga tcagcaaaaa atcaaagaac tttcaccaac actttctgct tcttatactc
    34861 aaaaagaaga tgcgggaacg atttactata atgcaagtga atttgcggct caaccattga
    34921 tcatgataaa acatgaagat ggaacaccgc cgaagatcac gaaagaaaaa gttcctgcta
    34981 aaaaaatgaa tgaactgact gtacaagagg aacttcgaag ctatgaattg ccggaacagc
    35041 aagaaaaaga aatcaaggta gtcagtcaat cagaatttga tcaactgaac ttgccacaat
    35101 ccactttaca gctagttcag gtaaaagact tccaagcaaa cctgaaacca atcgaaacac
    35161 ttgttgctca aaataaaatg aacaatccat ctttgcaaaa agtagagtac agcaaccaga
    35221 aatatgaaat gtatgaagtg tataatggtc tattctctgg ttttgaattt atgggattct
    35281 tcctaggttt agctttcttg accatgcttg ctagctgttt gatgttcaag atcttgtcag
    35341 gaagcaagag tgacattgct cgttatgaaa tgcttgaaaa gataggaaca cgacgcgggt
    35401 tgcttaaaca atcgatccgt agagaagtag gcgtgttatt cttagcacca ggaatcttag
    35461 gtgtagtcca tgtcttattc ggattacaaa tgtttggtct attcatgcaa aatccataca
    35521 aagatatttg ggttccgttt acgatattct tcgtattgta tttcatctac tatgtactga
    35581 cgacatggtt atatactgga atcgtattga aaaagagatt gtgaaaaagc tgtcctgcat
    35641 caagtaataa gaacagccaa gcaaaaatag ctcctcatat ttttcgtttg gttgggctta
    35701 ttaccgcaga tgcaagcttt tgaacaccgt ttgttcggaa aaagaggttg tgacaatatt
    35761 tttgtcacaa cctttttttc acggtctttt attagaatat agtaaatttt ttctcgttac
    35821 tcacggaata agctgttaag aaaacggttt ccatgtatac tggaatcagt gcaaatgaaa
    35881 gaaaagaggg tgcaaggaac atggaaatca atgaacaaaa ttttggcgaa aactatcact
    35941 tgattacgat cacgaatcaa aatgggacat ctttgtctgt cagtgatctt ggggcacggg
    36001 ttgttcattt tcaaacaata atcgataatg aaaaacgaga gttgatctta ggttttgatg
    36061 aagcaaaaga atatctagaa aaagaccctt atatcggtgc ttcaatcgga cgtatggctg
    36121 gacggattac gaatggcaca ttcaaattag atgatgaaac gttcgaagta aaaacagacc
    36181 cggacactgg tcattgttta catggtggtg cacctagctt tgaagccaag cagtggcatt
    36241 atacagtcat caatggtgaa aacgaagcat cggtcatttt ctatcagact agcccagata
    36301 tggaaaacgg atttcctgga actttagatg tagaagtacg gtatacgctg acgaacgatg
    36361 atacatggcg agtgacggtc caagggatca gtgaccgcaa aacagtattc aatcctacaa
    36421 atcatgtcta tttcaattta accggtgatc cagcacagtc aatcgacgaa catatacttt
    36481 ggttgaatag ccgattattt gctacgctca ataaagatac aacgcctaca ggagaagtag
    36541 tttcagtaag tggcacagca tttgacttcc aacgtcctaa aaaattaggt gaggtctttg
    36601 ccagtgattt tcgccaatca atgatagtgg gcggcatcga tcatccattt ttgttgaaaa
    36661 aacaatctgg tttactaaat gctgcggaat tgacaagccc agatgaaaaa gtatcgatcc
    36721 aagtaaaaac agatgcttca ggaatcgtga tttttacagc aaattttgga gaagatggac
    36781 cggaaatgcg cgggaataaa ttagtaaatc atggcggtat cacatttgag actcaagaac
    36841 tgccaggagc ggagcgactt gaaagttttg gagatgtcac tctggaacct aaccaagtac
    36901 gcgagtttgt aacggaatac aaaataaata taaagaaata gaataaatta aaaagggagt
    36961 gtgacagtgt cacatcccct ttttaattta ttctatttct ttaaaggcag atcaagccag
    37021 aatgatttgt ctaaacttaa caaggttagt acaggaacag ttgcagcttt aactgtacga
    37081 gtagttgttt ctggtatctg tcttgccgta aaattgttcc acaaatccca gattgaagcg
    37141 acacggaaga tggaagaagc gttgttgacg cgttttatcg ttgaaaattc taatcctgtg
    37201 attggcacgc catctgttgt ccatttgatt ggcacatcga atcgcttaga catattgagg
    37261 atttcagcgt ttgcttcttc agttgttgct gcttcttttt tcggttcatc atattttgtc
    37321 aggtcgtacg cttcgatgat cgcgttcaat ttttgtgaat attggcgatc tgtagcataa
    37381 cgtccttcca aatatttggt tgcttctttg tagtcttttg tttccgactt ccaagttggt
    37441 ttgtagaaat caggattgcc agtcagtcca tttttgatca agtcggcata gtcttccaaa
    37501 ctttccttgt aagaaggata tttacggaat tgtgcgcgga tttggtagct ttgtccggaa
    37561 ctatcttgtt caagtgtatt gaaggtcacg ctgcttcctt tatatgatcc tttgatacca
    37621 aaaaggttat gatttggttc gcttgataat aagctgtttc cagatccact ttcaaggata
    37681 gcttgagcca tcatgactga tgcgtagatt ccttcttttt gcccgatttc ctgtgcatca
    37741 tctgcaatct ttttcaagaa ctgatcagtt gtttggtttt gactgaaatg gaacgagcca
    37801 tctaatccat ctaaaataga tgagccgcct gtcagcgaac ctgaagcagc aggtaaacct
    37861 gctaagttta ctcggacagc aaaatcaggc gtgaaatctg aaatagaagt tactcgaact
    37921 ttatctcctg gttgaggcgc atggataaat tgtccgttcc caatatagat acctacatgg
    37981 tgagtaacac cggaagaagg tccccagaag acgaggtcgc caggttgggc ctgacttact
    38041 ggaatctgcg tacctgcata ttgctgttcg cctgtccagc caccgatata atgaccggtt
    38101 gctttcatat atacgtaata agtcaaacca gaacagtcaa aagtatttgg accttttgct
    38161 ccccatacat atggttttcc aagatgcttg aatgcttctc gaacgattgc ttgttggaca
    38221 ttcgttgtat ttgtaggcaa tacagcatca attggtgatt ttacaacaaa atcagaagaa
    38281 gcagaagatg gattctctat accgctttga tttgctgtat ttggacgaga tgaagcattg
    38341 ttcgttccgc cattcgatga accattgttt ggatggtttg gttctctctg agtatttcca
    38401 ttgttattcg atccagatgg gtttgtttga ttcgaagaat tcccgctgtt cgaattattg
    38461 ttattattgt ttgaattatt tgaaccatta ttattgttgt tattacccac atctggtttg
    38521 tttggcgttt ccggatctgg tgtactaggg acttcttcac taggatcagt tggtttctct
    38581 gttgaagtat ccggtccagc tttaaattct gcagtaatag ataaattgtt cgtacctact
    38641 gtaaaggtct ttgcatcata atttacttct ttggcaccat taacagcgac tgaagcaatt
    38701 tgttcacctt cagctggcgt aatagtgtaa gttaccttcg tttccgctaa taaaccttct
    38761 accgttccac tttccgtaat atccaaaggt tgctgttcag gggaatccgc tgtcgaagca
    38821 gtcagttgga tcttaccaat caaagaagga gcaattgtaa gggaatatgt ctcggctggc
    38881 ttttcatttt ctgatggatc agccggatca atttcagttg gctcggtcga tcctgttgtt
    38941 gagttagttg ttccagttgg gtcttctgta aaagaatccg ttgtttcact agtagctgag
    39001 ctggatgtag tcgtatctgt tgtgactgtt tgatcagcta tttgattatc tacggcaaat
    39061 acggtattgg tcgacaaaac agacggagca atcagccaag tagcagctag caaacgtatc
    39121 gtttttttat ttttcataat aaactagtcc ttttcctttc attgattttc tgtcttattc
    39181 agcattcatt agacattttt tggaacagat aatcgtgtcg aaaagctttt tcttttcata
    39241 aatctgtctg tgtattctaa ataaaacaat ttgtaaataa gcaacgagca ttcattcgtt
    39301 tttctttgac gttcatttta ttgcatagac cacctttgtt tggggataaa caagtgggga
    39361 taaaaatggt tatgcatatg taaattatac caaagtttgg aaagtatcac aaaaatttat
    39421 aaaaataatg atcctaaaaa gaaaaagact gaaatatgtg ataaacatct catacttcag
    39481 tctttttcat taactattca taagacatta ggtcttcatc aaacccgcta acgagagtag
    39541 tgatcattgc tacgactaga ctaacagcca gtcctgctaa gtaccagaaa aaagtaccgg
    39601 aaatgaatgc aggcaatgtg gtcagactac caaatacaaa agcgatcgct ttcacttggg
    39661 caaatcccat tacagctcca ccagcagctg caccaatgca agcagcaaca aatggttttt
    39721 tcaatgggat cgcaattccg taaacagttg gttcggtcac tcccgcaagt aaaatcgaag
    39781 caaaagcaga accggagatc gaacgggttt ttgaacgttt acttcgcaga aatacaccta
    39841 aagctgcacc agccattcca aaattggctg ctcctgtcaa cggaacgatt cggtcgaacc
    39901 cataagcaga gatattactg atcatgacag ggtttacagc ccattggata ccaaatatta
    39961 ccaaaatatt ccaaccacca gcgatgattg cgccactgat cggtccgtta atatccatca
    40021 tccaagtaat tgcggcagct aaaccttcgc caaggtaaac acccgcaggc ccgaatacca
    40081 ttaacgtcaa aggaaccgtg ataactaatg aaagtaaagg tacaaatact aattgcatat
    40141 tttcgcgaat atattttttg aggaattttt caacaaaaga ataaaagaaa atacctaaaa
    40201 tcgccggcat gacagtagac gtatactgca tcagtactac aggaatcccc agaaaatcag
    40261 tagctgcttt gccactgtct gaaagtaaag aggtcagatt cggttcaatc agtgctgcag
    40321 caatgacagc cgcaatatat ccattcactt taaacgtttt ggcagcagaa aaagcaagaa
    40381 agattggcag aaaataaaag acggcattcg acgcagcaga caaaatatga taagttccgc
    40441 ttgtttcact aagccagcca atcgtagtcg ctaaaacaac cagacctttt aatataccag
    40501 aaccggcaaa cagcggaatg atcggcgtaa agatttccga tatcaaacca aatagttttt
    40561 cgatcggatt tagcttttct ttcggagctg aatgatcgat ttgacgcgtc aattccttgt
    40621 aagcaggagc caatccctga tccatgatta tttctgcata tctatcgagt aaaatgaaat
    40681 acttaatgga agggatttgc tgttttaatt tttctgcatt ggctactggc tgttttttca
    40741 atttgatacg aagccgagtc gcacatggaa ggacagaatc aatattgtct tttcctccca
    40801 actgttcaat cagcatatga atctgctcgg acagtaccat ctgttcagga ttcattgtcg
    40861 tttccattag aagaccactc cactcactaa tataatattg gcgtaaggtg tcatttcgcc
    40921 tgtacgaata aatgcatgac agttattcaa ctcttttttc atttcttcat gtgggataaa
    40981 gctaatcggt gtatctggta acaataattt gattttttcc aatatttccg ggttcattgt
    41041 ctttatttct tccgccaatt caatcgattg tacctcaagt tcttctaaaa cgttttctaa
    41101 aacagataaa aaacttggaa gaccgtttga gacagccaaa tctatttttt cagtaccaaa
    41161 ggggacaggc atgcctgcat ccccgatact taatttatca aagtgcccca tttgtgcgat
    41221 tactcgtgaa atatctgaat tgattacttt tccttttttc atgtttgttt cttcctctca
    41281 ttgttaattt tagactgctg attgttctaa agcttcgcgg taagggatag aaggttgcgc
    41341 accataagac tgcacagcaa cagaagaggc tagatttcca taaaggatcg cttctttcaa
    41401 gttactaagg tctggctgaa gtgtgctgct taatgcgcca ataaatgtat cacctgcggc
    41461 tgttgtgtca acggcatcca ctttaaaagc agggacgata ccgtgttctt tttctgtatg
    41521 atagaaagcg ccggcactgc ctagtgtaat gattactgtt ccaataccta attcatggag
    41581 tttttcggct gctgcgacca aactgttatg atctgtcact ctgattcctg taatgatttc
    41641 tgtttctgtt tcatttggta taatgatatc tgtcttttca agtagttcag taggaatcgt
    41701 ttcacgagct ggtgcaggat tcaggatcgt tgtttttcct gcgtcttttg caatagaaaa
    41761 agctaggatc gtcgcatcta agctactttc aaactgagca ataataaagt cactgtttgt
    41821 aatcagttgc ttgtttttta ggacttcttg ttcatggaaa gcattatttg cccctgcatg
    41881 gatcaagata ctattttctc ctgctgcgtc taccataatc attgcttgtc cggttgtggc
    41941 gccttggatt tcagctatcc cagatgtatc gatgttttct tttgtcagta gatctaataa
    42001 ctgttgtcct tcgctgtcag ccccaacgcc tccaataaaa gatgtccgtg cgcctgaacg
    42061 tttggctgcc actgcttggt tggcaccttt acctccgcca gcgtgaaaaa tctcatgcgc
    42121 atgcatcgtt tcgcctggct tgggcatgtt ggttaaacga agggtagtgt ccatattaat
    42181 acttccaatt actgtaaccg tgttcatttt acaaacctcc aactatctca tttattttga
    42241 tgggaaaatt attttttaaa acgttttagt aaaacgtttt aatagttcga taaaaatata
    42301 gcacaccttg aaagctattt caagggtgca gttgaaaatc ttttttctaa tcgtacaggt
    42361 aatctttttt cttcccattc tttttctggg aattggatcc gatctaacaa taacttggca
    42421 gatgtttgtc ccaattcgaa gattggttgt gcgatcgttg tcagtttcgg cttgatatac
    42481 tcgcacatat ctatattatc atagccaata atgctgtagt cttcagggat gctttttcca
    42541 gcttcctcta atccgcgata taatccaaaa gctaattcat catttaaagc aaacacacca
    42601 gttgcagcag aatcaagaag ttctgctgtg atctggtagc caccttgttt tgagaactgt
    42661 gtaggtaaga ggatcagttg gtcgtgaggg atttggtaaa catcaagagc agatttaaac
    42721 ccctcaatcc gagcgtggac attttccggt ggattttcag gatagacaag ggcgatcgtt
    42781 tgatgtccta gactaagcaa gtgcatgccc gctaggtaac caccgcgaaa atcgtctgtt
    42841 cgtacggcat cactaaatcc ttcagatttt ttctgatcca aaacaatgaa gggccggcct
    42901 tgttttttca aattttcgtt gattgcatct gtagagacag cagaagtcgc gataatgaat
    42961 ccatccacac ctcgacgtgt gagctcggct agatattcga tttctttttg atgatcagaa
    43021 tcagcattac ataatatcgt gacgaaattc tgcttataca agatatcctc aattcctcgc
    43081 atcagtgtac tgaagaatgg attcgtgata tcaggaacga gtacaccaat tgttttcgtt
    43141 tccttggtaa tcatttgtct agcaaaatag tcaggctgat agcctaattc ttctttggca
    43201 gctaaaactt tctgaacagt tttcggactg aatttctccg tatttccatt taatatcaag
    43261 gagacagttg tgattgaaac gccggaaagt ttagcgactt ctttgattgt gatctttttt
    43321 ttcaccatgt tcatactcct atctaaatcc tgtggttatt ttcccatgaa atcaaaaaga
    43381 agtaaatgaa aatcacgtgt gccagtactt atttgctttg ttggatagct tcgattattt
    43441 gtttcgttga gcgtactcgt gcagttttcg gaaatatctt ttttatgaac aattgatggg
    43501 attctttgtc acgatcactg caagcatctt cagcaagcac gatatggtac ccgtgttgaa
    43561 aggcatctaa tgcagtagca tatacaccgt ttgttgtcgc tacaccgctt aaaatgatag
    43621 tttcgattcc acgccggcga agttgaagat caagagaagt accaaaaaag gcacttggat
    43681 tgtagtttgt gatagtcaac atattgtttg tatctttcaa ggaatccttc aacaacaagt
    43741 cagtgaattc tgccggagca gacaaagcag atattcctcc agcatctgtc tgatgactta
    43801 gataagagaa agtagtgatg tctacattca ctaaaacttt caaggcagcg gtacgtttca
    43861 atgtttttgc taacaaatca ttgtttgtca gaatagattg tgcagtgtgt ggagagagtg
    43921 taccgttatt tacgatccct ttttgcatgt cgatcgcgac aaaagcagtt tttgataaat
    43981 caaaaatcat attttccttt aaatcattca tgatgttcct tctttcaaat aacaatgttt
    44041 tttatgtaag taaatcataa atcgtttatt tgtcaactaa ataaaggatt cctttcttta
    44101 gtctagagaa attcagtggt aaaataaata agtgtgagaa aacgcattcg atgcatagat
    44161 atagcgagaa atatcgtgaa aatggaggaa tcagagtgaa gtatgtcgaa gtaaaaaatg
    44221 aatacaaacg atacaaaatg ggagaaacga ccattacagc aaatgacgat atttcttttt
    44281 caattgaaaa aggcgaatta gtgattatac ttggtccaag tggagcagga aagtcaacga
    44341 ttcttaatat tttaggtggg atggatacac ctgatgaagg tcagatcatt attgatgaca
    44401 cagatattgc gcaattttca gataaacagc ttactgctta ccgacgaaca gatgtagggt
    44461 tcgttttcca attctacaat ctcgttccta atctaacagc aaaagaaaat gtggaattgg
    44521 caacggaagt ttctcctgat gcgcttgatc ctgtagaggt attgaggcaa gtgggcctag
    44581 ctcatcgatt gaataacttt ccgtcccaat tatcaggagg cgaacagcag agggtttcaa
    44641 ttgctcgtgc actagctaaa aatcccaaac ttcttttatg tgatgaaccg acaggcgcgc
    44701 tggattttga aacgggcaag caagtattga aattattgca aaacgctagc agacaacacg
    44761 gcaataccgt tttgatcatt acacataatt ctgctttagc gcccatcgct gatagagtca
    44821 ttcacattaa tgatgctaaa gtaaggtctg ttgaattaaa tgatcatcct tcatccattg
    44881 atgagattgt atggtagggg gattttatga aaacaagaac atatcttaaa gcaggttttc
    44941 gcgaaattcg gcaatctaaa ggacgattca ttgcaatcat ccttattgtc atgctaggaa
    45001 cacttttatt tgtaggtgtc aaaactgctg gacctgtcat gcaaaaaacg atggatcact
    45061 atgttggtac agcaggactt tctgatttgc aaatcgtttc tactggtggc ttgacacaaa
    45121 aagatattgc tcaagcagaa aagatcccag atgcaaaagt agaaacagga aaacagatct
    45181 attattccaa tactggcaaa aacgaagtga ttcaaatatt ttcttataac aaaaataaca
    45241 agcagaacaa gctacaatta actgatggaa aactcccgga aaaaccaaac cagcttgtat
    45301 tggatgaaaa agcggaagat gaagggtata aaatcggtga tatttatcag attgattcag
    45361 atgaattgaa agaaaaagag tataccatca cgggctttgt ccgttctcca ttgttcatca
    45421 acaatttgga gagaggatac gcgaacatcg gaaatggtag cgtcgattat tttgtctatt
    45481 tgcctgaatc cgcttttaaa acagatattt attctgtctt atatcttgat tttacaaacg
    45541 taaagaattt gaatacgtac agcaaagctt acaaagataa aatggagcaa aatcaagaaa
    45601 aggcagaaaa gtatttacaa gatcgacccg aagaacgctt agaagagctg aaaaaatcgg
    45661 ccaacgaaga attagaacca gcacagcaaa aaataacaga aggcaaagca caaatagcac
    45721 agggaagaac acagttagaa gatgctaaaa aacagttagc gcaacagtca gcagctatcc
    45781 agcagcttcc tgaagcgcaa cgaacaatcg ctgttcaaac attatctcaa caagaagctc
    45841 aacttgctga acaagaaagg caattagttg agaaagaacg tgaactggcc tctgcagagg
    45901 aagaattgaa tcgaaatgca gaaaaaattg aaaatttaac taaaccatca tacctataca
    45961 atgaacgttc agaaaatgtc ggttttcaag aatttggtga tctgtctgat cgtatcgctg
    46021 cgattgctaa tgtttttcct gttttctttt tctttattgc cgcattgatc acctttacga
    46081 caatgacacg tatggtagaa gaaaaccgca gggaaatcgg gacattaaag gcgttaggtt
    46141 atacgaaagt tgaaatcgca aaaaaatatg caatctatgc aagtctagcc tcagggatag
    46201 gcattgtttt aggaacgata ttaggaacga atcttttgcc aaggatcatt tttgagctgt
    46261 ctaacgagcg gtatgatatt gggagtgcgc ttatttttta tgactggccg ccgattttac
    46321 aagcagctgc cgcattcttc attgccgcat ttggcgctgc aatgatcgtt ttattcaaag
    46381 atttaagaga acggcctgct gcattgcttc aaccgaaagc accgaagcca gggaaacgca
    46441 tttttcttga atacatcact ccgctgtggt cacgccttag ctttaatcaa aaaatcagtt
    46501 accgaaatct cttccgatat aagtcaagaa tgcttatggc gattatcgga attgctggat
    46561 gtgccgggct gatggttgca ggcgtgggat taaaagattc tctaagttct gtctcagcca
    46621 aacaatttgg accgatcatt gactatcaag caatcgttac attggattca tccacggaag
    46681 atagtcgtca aaaagcagcg gatatgctgc agaagcaaga aaaagtaaat gagatcctag
    46741 ctattcatac tcaaaccgta gaattgagaa aaaaaggaca tgcttcgcaa agtctgacag
    46801 tgatcgtacc aagtaaaaca gctgatttgg atcgttttat ccatttaact gatcttgaag
    46861 agaacccacg ctccttgcct aaaacaggaa tcgctattac gcaaaaagca gcagaactat
    46921 ttgacttatc tacaggagat catatttcgc tttatgatga agatcaaaaa gaatggaaag
    46981 tcgaagtaaa agaaatcgtg aaaaactatc taggtagctt tatttatatg tcccctgaat
    47041 attatgcttc agttactgat caatcgatga tggataatgc atttttgctg cgtacagata
    47101 agatgacaac gaaagaagaa gaaatgcttt ccgagaaact gcttgccaca gacgctgtga
    47161 caaatacgtc tttcatgtcc aaacaaatcg aaacgcaaga agaatcaatg gcgaacttag
    47221 actcggttgt cttaatcttt gtcgtattat caggactgct ggcttttatc gtcttgtata
    47281 atctaactaa tatcaatatt tccgagcgtg tacgcgaatt atctacaata aaagtccttg
    47341 gattttttga taaagaagtc acgatgtaca ttgttcgaga aaatatcatc tttactcttt
    47401 taggaatcat cggaggattt ggtgtaggat atatattgac tgacttcatc ttgcaacaag
    47461 cgtctatgga gaatgtcatc tttccattag tgatcacatg gtgggcttat gtcttatcag
    47521 caggattaac tatcgtattc acggttattg tgatgatcgt tacccatttc aaattaaagc
    47581 atatcgatat gattgatgcg ttgaaatcga atgaataaaa acagaggttg tgaaatcagc
    47641 ggttgtgaaa aagctgtcct gcatcgagca aaaagaatac tcaaataaaa ttagctcctc
    47701 atgttttaca tttgagaaga ctgattgccg tagataaaag cttttgaaca ccatttatag
    47761 aagaaacaag aatattttgc tattttaaac aagaggatag acaaatacat gtctgatctc
    47821 ttgtttttta ttgggcaaca gacctcttag aatgtataaa gataaatttt acaaacgctt
    47881 tcggttcagt tataataata aatgataact tgtatatata agttgtggta ggtaataaat
    47941 cagttgaatg gaggtaaata tccatgacat ttaaagacaa agtcatttac caaatctatc
    48001 ccaaatctta caaagacagt aatggtgatg gaattggaga tttaaaagga atcaaagaaa
    48061 aactcccgta tctgaatgat ctaggcatcg acatgatttg gctaaaccct atttatccaa
    48121 gccctcaaaa agacaacggt tatgatatct ctgattacac agccatcgat cctatctttg
    48181 gtacgatgga ggaattcgaa cagctaatag ccgaagcaaa gaaataccgg atagaaatca
    48241 tgctcgatat ggtgctgaat cacgtttcga cagaacatga atggttcaaa aaagcactag
    48301 caggggacca gcattatcag gacttcttca ttttaagaga agagccaacg gattgggtat
    48361 caaaatttgg tggaagtgct tggtcgccat ttggagatac ggggaaatat tatttgcact
    48421 tatatgatcg gacacaagct gacttgaact ggcggaacca agcagtaaga gaggaactat
    48481 tcaaagttgt tcgtttttgg atggaaaaag gggtaaaagg attccgtttc gatgttatca
    48541 atgttatcgg taaagacgaa caattgaaaa ataataaaga aaatgatggc aaacctgaat
    48601 atacggacaa accaatcacc catacgtatc taaaagaatt gaaccaagca acgtttggga
    48661 cggattccac tatcatcaca gtcggtgaaa tgagctctac gacgatcgaa aattgtatct
    48721 tgtatacaga acctagtaga gaagaattat caatggtctt taatttccat catttgaaag
    48781 tcgattatga aaatgggaat aaatggtcta ctcctccatt tgattttgca gaattaaagc
    48841 gactatttca tacatgggga gaaaagatga gtgagggtaa cggctggaat gctctatttt
    48901 ttaataatca tgatcagcca cgtgcgctca atcgatttgt agctatcgat cagtatcgaa
    48961 aacaaggagc agagatgcta gcaaccatga tccatttgaa ccgtgggacg ccctatattt
    49021 atatgggaga agaaatcggc atgatcgacc cagactattc atcgatttcc gactatattg
    49081 acgtagaaag tttgaatgct tataagttac tccttgaaca aggattcaca gaaaaagaag
    49141 cgtttcgtcg gatcaaagca aaatctcgcg ataactctcg aacacccatg caatggtcag
    49201 acacagaaca agcaggattt actacaggga aaccttggtt aaaagttgga ggcaagctag
    49261 aagagattaa tgtagaaaaa gaactatctt ctgaagattc tattttgtcc tattacaaga
    49321 aattgattcg gctgagaaaa acatatccaa tcgttgcaca aggagattat catgcttatg
    49381 aagcaaatca tccggaagtt tatggctttc ttcgccaatt tgaaggacag cagctgcttg
    49441 tattaacaaa tttctatgat aaagatacaa ggatcgccat cccagaagga ttcacagaag
    49501 ccaatattct tatcgataat tattccgata ctgttcttca tcaaagtctg gagctaaaac
    49561 cataccaggc aattgctttg ctgaaaaatt aaaacaaaaa cacaaaacgt cgttcctacg
    49621 agctattctc gtaagatcga cgttttgtgt tttatttaaa ataatcttct tcagaaaatg
    49681 aagagttttc atactctcct ttatcgccat aaaatttatt gtagcgttgt ttgaatttac
    49741 ggaaaataaa agtaacgagt aatttgacta acgtatagat aggaatacca aaaataacgc
    49801 ccacaattcc cattagatca cccatgacaa gtaaaacgat taagatcgta atcggatgga
    49861 tctgtaaacg atcacccatt actcgaggaa tcaccaagtc accgtggaga agttgtacgg
    49921 caaaccagac aatgacaaat ttgacagcca taaaagtaga gtcttggaat gcaatgatca
    49981 aacctggaaa gaaggcgata aacggcccaa tatatggaat gatacataac aacccagcag
    50041 aaatagctaa aacactagca aattctaatc cgatcagtaa gaaacaaacc cagtagactg
    50101 ctccaaggat aaatgaagca atgatttgcc cctttagaaa tgaacccaat tgttgattag
    50161 caatctttgt caaattttta aaatctgtac gaaatgctgg tgggacaatc gctaaaactg
    50221 actgataaaa tttttgagga tctctcaaaa ggaaaaaagc gacaattgga ccagtaaata
    50281 aagtaataaa aatagctgta acagttgaaa aaatgttgct gatccgttgt gcgccacttt
    50341 cccaataatt tccaataaat ccagctatat cagacgtcac gtcgtcaata gaagcgaaaa
    50401 attgattaaa tgaatcggca aaaggtgttt tctccaaaaa ttgtcggaga ctctcttgaa
    50461 aatcttgaaa caaatctggc aaactactga tcaatgtctt tgcctgttct tcaagaaaag
    50521 gaataagcca tatgcttcca agccccaata aaaataaaat aatcacataa acgataatga
    50581 ctgacaagtt cctcgaaagg tgcttgctca aacgtttgat gactggttcc aaaagataat
    50641 acaagatcag tgcaaacaat aatgggggca agatagtagc gataatgatt ccgacaggct
    50701 tgaatataaa cgagatctga tggaaaaaat aaatgatcag cgcaagtaag ataactattc
    50761 ctaaaacata gtaagaggtt tttcctccta aaaagcggat caaacgattc gttgtatctg
    50821 tttctttttt cactcttttt cctcctttat ctataacttc attatagaca aaagcgggta
    50881 taaaaggaaa atgatagagg ttgattgcaa aaatatcgtc aatcattcat ataaactttc
    50941 tcatcaatta aaataagaaa acgcttgaca gttcttttaa ccatatgata aattaaatcc
    51001 tgttgctaaa acgtaactat tacggtttgc gaaaagcgaa tcggaacatt caaatgaaag
    51061 aagatgagaa gaggagtgtc ataaatgaaa cgattgatag gtatattggc catgctggtt
    51121 ttagcaggta tgttaactgc ttgcggggca agtgggaaag ccgaggacag taaagaaaaa
    51181 ttgagcgtga tgacgacctt ttatcccatg tatgatttta caaaagcaat cgtcggggat
    51241 gaaggagaag tagagttatt gattccagca gggactgatt cccacgatta tgaaccttct
    51301 gctaaagaca tggcaaagat ccaagataca gatatctttg tttataatga tgaaaacatg
    51361 gaaacatggg tccccgcaat ccaaaaaaca ttacaagaag gcaatgtcca tacgataaaa
    51421 gcgacagaag gtatgctttt acttccggga agtgaagaag gacatgatca tgaccatgaa
    51481 cacggggaag aaggccatac acatgagcta gacccacatg tatggctagc tccaagttta
    51541 gcaatcaagc aggtagcaaa catacgtgat cagctgattg aagcttaccc agaaaaacag
    51601 gaagtatgga caaaaaatgc agcagcctat accgagaaac ttcaagcact ccatcagctt
    51661 tatcaagaaa cctttaagca agcaaaacaa agatcttttg tcacgcaaca tgctgcattc
    51721 aactatctag cgttagaata tggattgaat caagtatcga ttgctggtct ttcttctagt
    51781 gaagaaccgt ctgcggcgag aattgctgaa ctgaaacact ttgttaaaga acatggaatc
    51841 aactatattt attttgaaga aaacgccaaa gatagtattg ccagaacgtt agcaaacgaa
    51901 gcaggtgtat ctttagaagt attgaatcct ttggaaggat tgacgaatga acaaatagaa
    51961 aatggagaaa actatctttc tatcatggaa gcaaacctcg aagcgttgaa aaaaacgaca
    52021 gagacagaaa acccgctaga agatactttg acccccaaaa aagaaaagag cgtctacaac
    52081 ggttattttg aagacgagga tgtacaagat cgctctcttt cagattgggc aggaacttgg
    52141 caaacagtag atacgtatgt agaagatggg acttttgatc ctgtttttga atataaagaa
    52201 aaattgaatc aggataagac agcacaagaa tataaagaat attatacgaa gggctatcaa
    52261 acagatattg cttcaatcaa gatcagtgag aaagagatgg catttacgtt taagaatgga
    52321 acaacgaaac gttcaaatta tcgttatgta gggaaagaaa tcttgaccta cgaggcagga
    52381 aaccgtggcg taaggtatct attcgaagca gaagataagg aaagtggcgc ttttagatat
    52441 attcaattca gtgatcacac gattgcaccg gctgactccg aacattttca tttatatgca
    52501 ggaaatgaaa gtcaagaagt attgctgaaa gaaatggaga attggccaac attttatcca
    52561 gatacaatgg atggacgtga aattgcacag gaaatgcttt tgcactgata ggcaaaaaag
    52621 aaccgaaggg tttggatcgg ctggtcattt agtcggtcca aactattcgg ttctttttat
    52681 gaaatcaatt tctttaatcc acggatagag gctgggatgg tctcgccgtt tgccaacgtg
    52741 acttctctgg tttttttatt aatcgaccgc acattttgtg tattgataac ataggattta
    52801 tgacaacgga taaaattccg atgcattttc tcgatttctt tgatcttctc atagaattgt
    52861 aattgggcat gagtcaaatg gacttccagt ttatgtggcg ctcctagcga agtagaaaaa
    52921 tattggatgt ctttgatcgg taaaaatttg atctcatcat taaactctat tttgaagata
    52981 tctttttgga tttgggacat ttgaaaatct tcgaaaattt tgctcaggat atgctcgaca
    53041 ttttctttta aatcataaag atcttctttg acgatataat cagtcggttc gatgttgctt
    53101 tttaagattt tcatcgacat ttccgtatgg gaagtcacat agattatttt tcctaaagga
    53161 tctaattcac ggatcaattt accgatcgct acaccatcca tttcactgtc ttctagttcg
    53221 atatctaaaa agtaaatacc aaaagaagaa gttctgatct tggctgcatt gagaagttct
    53281 tccggatcag aggtagaaat atggacataa ctgtctaagt tttcaatcat gattctattt
    53341 ttgatcaccg ttgataaaac ttctaattgt tttggatcgt cttcacaaat ataaatggga
    53401 atcatatcat tactccttta ttttatttgt a
//
LOCUS       DAFKHN010000011        53368 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFKHN010000011 DAFKHN010000000
VERSION     DAFKHN010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.011"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(138..515)
                     /locus_tag="LY912_000639"
     CDS             complement(138..515)
                     /locus_tag="LY912_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954356.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            771..1499
                     /locus_tag="LY912_000640"
     CDS             771..1499
                     /locus_tag="LY912_000640"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBM6954357.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1499..1753
                     /gene="purS"
                     /locus_tag="LY912_000641"
     CDS             1499..1753
                     /gene="purS"
                     /locus_tag="LY912_000641"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBM6954358.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1755..2426
                     /gene="purQ"
                     /locus_tag="LY912_000642"
     CDS             1755..2426
                     /gene="purQ"
                     /locus_tag="LY912_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBM6954359.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2427..4649
                     /gene="purL"
                     /locus_tag="LY912_000643"
     CDS             2427..4649
                     /gene="purL"
                     /locus_tag="LY912_000643"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBM6954360.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4634..6073
                     /locus_tag="LY912_000644"
     CDS             4634..6073
                     /locus_tag="LY912_000644"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBM6954361.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6096..7148
                     /locus_tag="LY912_000645"
     CDS             6096..7148
                     /locus_tag="LY912_000645"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBM6954362.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7145..7723
                     /gene="purN"
                     /locus_tag="LY912_000646"
     CDS             7145..7723
                     /gene="purN"
                     /locus_tag="LY912_000646"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBM6954363.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7720..9255
                     /gene="purH"
                     /locus_tag="LY912_000647"
     CDS             7720..9255
                     /gene="purH"
                     /locus_tag="LY912_000647"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBM6954364.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9271..10545
                     /gene="purD"
                     /locus_tag="LY912_000648"
     CDS             9271..10545
                     /gene="purD"
                     /locus_tag="LY912_000648"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBM6954365.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10667..11581
                     /locus_tag="LY912_000649"
     CDS             10667..11581
                     /locus_tag="LY912_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBM6954366.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11714..13279)
                     /locus_tag="LY912_000650"
     CDS             complement(11714..13279)
                     /locus_tag="LY912_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBM6954367.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13272..14723)
                     /locus_tag="LY912_000651"
     CDS             complement(13272..14723)
                     /locus_tag="LY912_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBM6954368.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14737..15753)
                     /locus_tag="LY912_000652"
     CDS             complement(14737..15753)
                     /locus_tag="LY912_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6954369.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15973..17061
                     /locus_tag="LY912_000653"
     CDS             15973..17061
                     /locus_tag="LY912_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBM6954370.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17115..18641
                     /locus_tag="LY912_000654"
     CDS             17115..18641
                     /locus_tag="LY912_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBM6954371.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18643..19848
                     /locus_tag="LY912_000655"
     CDS             18643..19848
                     /locus_tag="LY912_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6954372.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20105..21082
                     /gene="guaC"
                     /locus_tag="LY912_000656"
     CDS             20105..21082
                     /gene="guaC"
                     /locus_tag="LY912_000656"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBM6954373.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21346..22770
                     /locus_tag="LY912_000657"
     CDS             21346..22770
                     /locus_tag="LY912_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBM6954374.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23231..24340
                     /gene="pdhA"
                     /locus_tag="LY912_000658"
     CDS             23231..24340
                     /gene="pdhA"
                     /locus_tag="LY912_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBM6954375.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24343..25320
                     /locus_tag="LY912_000659"
     CDS             24343..25320
                     /locus_tag="LY912_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBM6954376.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25345..26988
                     /locus_tag="LY912_000660"
     CDS             25345..26988
                     /locus_tag="LY912_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBM6954377.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26996..28402
                     /gene="lpdA"
                     /locus_tag="LY912_000661"
     CDS             26996..28402
                     /gene="lpdA"
                     /locus_tag="LY912_000661"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBM6954378.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28564..28839
                     /locus_tag="LY912_000662"
     CDS             28564..28839
                     /locus_tag="LY912_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBM6954379.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28845..29612
                     /locus_tag="LY912_000663"
     CDS             28845..29612
                     /locus_tag="LY912_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBM6954380.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29780..31609
                     /gene="typA"
                     /locus_tag="LY912_000664"
     CDS             29780..31609
                     /gene="typA"
                     /locus_tag="LY912_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBM6954381.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31870..33642
                     /gene="recQ"
                     /locus_tag="LY912_000665"
     CDS             31870..33642
                     /gene="recQ"
                     /locus_tag="LY912_000665"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBM6954382.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33756..34058
                     /locus_tag="LY912_000666"
     CDS             33756..34058
                     /locus_tag="LY912_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBM6954383.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34061..35224
                     /locus_tag="LY912_000667"
     CDS             34061..35224
                     /locus_tag="LY912_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBM6954384.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35250..38678
                     /locus_tag="LY912_000668"
     CDS             35250..38678
                     /locus_tag="LY912_000668"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBM6954385.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38699..39823
                     /locus_tag="LY912_000669"
     CDS             38699..39823
                     /locus_tag="LY912_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954386.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39813..40250
                     /locus_tag="LY912_000670"
     CDS             39813..40250
                     /locus_tag="LY912_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBM6954387.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40234..40572
                     /locus_tag="LY912_000671"
     CDS             40234..40572
                     /locus_tag="LY912_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBM6954388.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40691..41251
                     /gene="rsmD"
                     /locus_tag="LY912_000672"
     CDS             40691..41251
                     /gene="rsmD"
                     /locus_tag="LY912_000672"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBM6954389.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41248..41739
                     /gene="coaD"
                     /locus_tag="LY912_000673"
     CDS             41248..41739
                     /gene="coaD"
                     /locus_tag="LY912_000673"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBM6954390.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41729..42772
                     /locus_tag="LY912_000674"
     CDS             41729..42772
                     /locus_tag="LY912_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBM6954391.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42931..43659
                     /locus_tag="LY912_000675"
     CDS             42931..43659
                     /locus_tag="LY912_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBM6954392.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43775..44020
                     /locus_tag="LY912_000676"
     CDS             43775..44020
                     /locus_tag="LY912_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBM6954393.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44017..44235
                     /locus_tag="LY912_000677"
     CDS             44017..44235
                     /locus_tag="LY912_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBM6954394.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44371..44910
                     /locus_tag="LY912_000678"
     CDS             44371..44910
                     /locus_tag="LY912_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBM6954395.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44903..47176
                     /locus_tag="LY912_000679"
     CDS             44903..47176
                     /locus_tag="LY912_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBM6954396.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47214..48260
                     /gene="holA"
                     /locus_tag="LY912_000680"
     CDS             47214..48260
                     /gene="holA"
                     /locus_tag="LY912_000680"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBM6954397.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48349..48603)
                     /locus_tag="LY912_000681"
     CDS             complement(48349..48603)
                     /locus_tag="LY912_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBM6954398.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(49003..49272)
                     /locus_tag="LY912_000682"
     CDS             complement(49003..49272)
                     /locus_tag="LY912_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954399.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49742..50197)
                     /locus_tag="LY912_000683"
     CDS             complement(49742..50197)
                     /locus_tag="LY912_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBM6954400.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50335..52263)
                     /locus_tag="LY912_000684"
     CDS             complement(50335..52263)
                     /locus_tag="LY912_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBM6954401.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52460..53293)
                     /locus_tag="LY912_000685"
     CDS             complement(52460..53293)
                     /locus_tag="LY912_000685"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBM6954402.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
BASE COUNT        17560 a         9197 c        11594 g        15017 t
ORIGIN      
        1 aataaccaaa aaagaagcag atccgttagc ggttctgctt cttttagttt attatatttt
       61 cttatcaata ataggaacct gattttaaaa gcggctacct ctttaccgtg cctctttaca
      121 tacaaaaaat agaggaatta agcgtaaatg gcttggctat tataactaaa atgctggtta
      181 tggagatgtt gcagcaagtt ttcgagaaaa gcgtattcca tctcttgtcc attgaataag
      241 atctggatac gataatgatt tttgaaacgc ttctgttcat gaatctgact gattgaaagt
      301 tcgcctttgt gttctgtctg ataaagaaaa gtccttttac ggcattcagc acagcgcttg
      361 gttgctcggc ggatttttcg gaatgtataa aaactagtat ctttattgca taaataaacg
      421 tctttgatcg acagcaaatc attatataga caggaacgtt cttcagctgt taattctgat
      481 aaaaaaagct gaccttgttt tattgcatct tccatcggca agtgcctcct cgaacccatt
      541 atccaaattt ttagttaatt ctaatatacc atcattaagt ataaatgtaa acgcttgttg
      601 atggtataag attttcgttt ctgataaaac acgaacatta aaagaatcta atgccttaaa
      661 tgtacatatt tttgttgatt tataaaaaga tgattgctaa aatttaaagt gaaaaaacga
      721 acaaaaaacg atgtatttgc ttttaatgta aataaaaagg agagacgtac atggagaaga
      781 aagaactttt gtatgaagga aaagccaaaa aaatatatct tacttctgat gagaacttga
      841 tttggataga atatttagat caagcaactg cgttgaatgg cgcgaggaaa gaccagataa
      901 gtggaaaagg agaattgaat aatcaaatca caagtgcaat tttccgttat ctgactcaaa
      961 gaggaataaa aaatcatttt attgaacaat tgtctaaaac cgaacaatta gcaaaaaaag
     1021 tacaaattat ccctctggaa gtggttatcc gaaatattgc agcaggaagt ttctcaaaac
     1081 gtctaggtgt tcccgaaggt aaagaattca tcaaaccaat cattgaattc tactataagg
     1141 atgaccagtt ggatgatcca tttatcaatg aagagcatat ctatttctta caacttgcaa
     1201 agccggaaga aatcagtgag ctgaaagccc aagcgttggc tattaatgaa attttgaccg
     1261 aattatttgc taaggtcggt ttggttttag tagatttcaa gctagaattt ggccggtcga
     1321 atggacaaat tttgcttgcg gatgaagtaa caccggatac ttgccgatta tgggatgaac
     1381 gtacgaatga acatatggac aaagacgttt accgcagaga tctaggtgat ttgatcccag
     1441 tctatcaaga agtatataac cgtctatcgg aactaactga agaaaaggag cgagtatgat
     1501 gtatttcgta aaagtatatg taacctataa agattcagtg ttagatcctc aaggggaggc
     1561 agtaaaaaaa gcagtccatc gtatgggata tgaaacaatc gaagatatcc gaataggaaa
     1621 atactttgag atacaacttg ctgatgcaga agaaccaatc gatacagtga ttgaaacgat
     1681 ttgtgacaag ctgcttgcaa atgtaaatat ggaaacatac cgatatgaaa tcaaaaaaat
     1741 ggaggaagta taacatgaaa tttgcggtca tcgtttttcc aggttcaaat tgtgacgcag
     1801 atatgttatg ggcagttcgc gagatcatgg gcgctgatgc cgaatttgta cggcatgatg
     1861 agtcctcttt agaaggattt gatggggttt tactgccggg aggattctcc tatggtgact
     1921 atttgagatg cggtgcgatt gctcggtttt ctacaatcat ggaagaagtg attcgttttg
     1981 ctgaagaagg gaaaccagta ttcggtacat gcaatggatt ccagatattg acagaagcag
     2041 gacttttgcc aggtgtactg agacgaaatg agtctttgca ttttatttgc aaaactgtac
     2101 cattgaaagt caaccccaag acggccttta cttcagagta tgaagccgac gaaataatct
     2161 atcttccagt tgctcatggg gaaggaaatt atttctgtga cgaagaaaca cttcaagaac
     2221 taaaaaaaaa taatcagatt gcctttactt ataatgacaa catcaacggc agcgtggaaa
     2281 acattgcagg gattacgaac aaagcaggga atgtgttagg aatgatgcct catccagaac
     2341 gtgcagtaga agacttgcta ggatcagaag atgggaaacg gttctttgct tccattttaa
     2401 aaaacttcgg aaaggtgacc gtatagatga aaacattgaa agaaccgaca gctgaagaga
     2461 tcaagaaaaa aagaatctat gccgaatggg gattgactga tgaagaatat cgaatgatcg
     2521 aagaagatat cttaggaaga atgcctaatt atacggaaac tggactgttt tctgttatgt
     2581 ggagcgaaca ttgttcctat aaaaattcta aaccggttct acgcaaattt cctactagtg
     2641 gacctcatgt gttgcaaggc cctggagaag gcgcaggcat cgtcgacatc ggtgatggac
     2701 tagcagttgt cttcaaagca gaaagtcaca atcatccttc agccgtggag ccttatgaag
     2761 gagctgcgac aggagttggc ggaatcatca gagatatttt cagcatgggg gctcgtccaa
     2821 ttgcgttgct agattcattg aggttcggcg aattagataa tccaagaacg aaatatttac
     2881 tagaagaagt agttgcaggt atcggcggat acggcaattg tatcggcata ccgactgtag
     2941 gcggcgaaat tgcatttgat ccttgttatg aaggaaaccc attagtcaat gcaatgtgcg
     3001 taggtttgat tgaacacaaa catatccaga aagggcaagc cgctggcgtc ggtaattcga
     3061 tcatgtatgt aggtgcaaaa acaggtcgcg acggtatcca cggagcaact tttgcctcag
     3121 aagaatttaa tcaagaagaa gaacagcaac gttctgctgt acaagtaggc gatcctttta
     3181 tggaaaagct gctgcttgaa gcgtgtttgg aattaatctt gcatcattcg gattctctaa
     3241 taggtataca ggatatggga gcagcaggac ttgtttcatc tagtgcggaa atggcttcaa
     3301 aagctggctc aggacttata ttgacattag atgaagtccc acaaagagaa actgggatga
     3361 caccttatga aatgatgtta tcggaatcac aagaacggat gttgatttgt gttaaatcag
     3421 gagaggaaga aaaaatccaa gaactatttc agaagtatga tctagatgca gtcactatcg
     3481 gtaaagtaac agacgacggg caatatcggc tatatcatca aggagaagaa gtagcaaatc
     3541 tgccagtcga tgcattagct gaagatgcac cagtttatca taaagaaatg aaagaaccag
     3601 ctcgaatcgt agaatttcag cagttagctc cttatcagcc agttatcgaa gaacctggac
     3661 aagtattgct tgatctgctg cagcaaccga cgattgcttc aaaacgttca atctacgaaa
     3721 cttatgattc acaagtacaa accaatacag ttgtccgtcc aggaagcgat gctgctgtga
     3781 tgagggttag agggacgaat aaagcgttag ctatgaccac agactgcaac gcgcgctatc
     3841 tgtatttgga tccaaaaatc ggaggacaaa tagcagtggc agaagctgct agaaatatta
     3901 ttgctagcgg tggtaagccc ttggcgatca ccgactgcct gaactatggt tctcctgata
     3961 aaccagaagt tttttgggaa ttatcgactt cagctgacgg aattgctgct gcgtgtgaaa
     4021 cgttaggaac tcctgttatt tcaggaaatg tctctttata taatgaaacg gatggtcaag
     4081 caatctatcc aacaccaatg attggtatgg tcggattgat tgaggatcat aaacatatca
     4141 ctactcagga attcaaaaaa tcaggggatc taatctatat attaggtaag acgtttgcag
     4201 attttgatgg cagtgaatta caaaagatgc agcttggaag aatcgaaggt gtgatccgaa
     4261 actttgatct atccattgaa aagagaaacc aagagttagt attgacagcc atccaaaacg
     4321 gattgattga aagtgctcat gactgttcag aaggtggctt ggcaattgca ctggcagaat
     4381 cagctttcaa acatcagcta gggatatctg tacagtttga attgtcctct gctcaattat
     4441 ttgcagaaac tcaatcaaga tttgtgttga cagtcgcacc ggaaaataag acacgattcg
     4501 aagaaatgat gggagatgct gctgttttag caggtaaggt gacggatgaa gcgataatcg
     4561 aaatttcagc aactgacggt cagatcaaaa tagaaactgc agtagcaaga aagtgctggg
     4621 aggatgcaat cgtatgtctt atgaagtgaa gagtttaaat gaagaatgcg ggatcttcgg
     4681 tgtttggggt catccagacg ccgctagtgt ggcatacttc gggctccata gtcttcagca
     4741 tcgaggacaa gaaggtgcag gtatcgtgtc caatgatcga ggaaagctta aggggcatcg
     4801 agatttgggg ctgctttctg aggtattcaa agatcaaaga aaattgcagc agttaacagg
     4861 agaagctgca atcggacatg tacgttatgc aacagcaggc aatggaagtg tggacaatat
     4921 tcagcctttt ctattcaaat ttcatgatca gtcgatcggc ttagcgcata atggtaactt
     4981 gatcaatgct cgttccctta gaaaagagtt agaggaaaat ggggcgatct tccattctaa
     5041 ctccgatacg gagatattga tgcatttgat ccgacgaagt gaagaaacag attttttaaa
     5101 taaattaaaa agtgctttga atgaagtcaa aggtggcttt gcctatttat taatgacaga
     5161 aacggcaatg attgccgctt tggacccaaa tggttttcgt ccattagcaa tcggacaaat
     5221 gaaaaacgga gcatacgtga ttgcctcgga aacttgtgca ttagaagtta ttggggcacg
     5281 ttttataaga gatgtccagc ctggtgagat agtgatcatc aatgacgaag gaatccagat
     5341 tgattgcttt acgaaggaca cgcagctttc tatttgttcg atggaatata tctattttgc
     5401 cagaccagat tcaaacatcg cagggatcaa tgtgcatact gcacggaaaa atatgggacg
     5461 gaatttagcg aaagaatcgc cagtaaaagc agatatggtc gttggcgtac ctaattcttc
     5521 tttgtcagcc gcaagcggtt atgcggaagc tagtggaatc ccttatgaaa tcggattagt
     5581 aaaaaatcaa tacattgccc gaacatttat ccagccaacg cctgagctaa gagagcaagg
     5641 tgttcgaatg aaattatctg ctgtacgagg agtagtggaa ggtaaaaagg tgattatggt
     5701 cgatgattca attgttcggg gtacgacaag cagacggatc gtccatcttt tgaaagaagc
     5761 aggggcaaaa gaagtccatg tgaggattgc ttctcctcct ttgaaatatc catgttttta
     5821 cgggattgat attcaaacgc gtaaagaact cattgcggca aatcacacga ttgatgaaat
     5881 caaagaatgt atcggtgcag attctttagg ttttttaagt gaagagggtc tgatcgaatc
     5941 gatcggtctg gaaaaagatg ctccgtattc aggattgtgt atggcttatt tcaacggaga
     6001 ttatccgacg ccgttatatg actatgaaga aaaatatcag gaatcactaa aagaaaaagt
     6061 atcgttcttt taaaagcaga ccaagaaggg agtatatgaa ttcaatggca aatgcatacg
     6121 caaaagctgg cgtagatgtc gaagctggat atgaagtagt agaacggatc aagaagcatg
     6181 tcaaaaaaac ggaacgttta ggtatgatgg gcgctatagg aggattcggc ggttgttttg
     6241 atttatcggt ctttcaatta aaagagccag tccttgtctc ggggaccgat ggcgtgggga
     6301 cgaaattagc agtggcaatc gaagcagaca aacacgatac aatcgggatc gactgcgtag
     6361 cgatgtgtgt caatgatatc ttagcacaag gcgcagagcc gttatatttc ttagactact
     6421 tagcaacggg gaaaaatgat ccgttacgtt tggaaaatgt agtaaaaggt gtagcagatg
     6481 gatgtgttca aggaaatatg gcgctgattg gcggagaaac agctgaaatg cctggtatgt
     6541 actcaggtaa tgattatgat ctagccggat ttgctgtagg gatagctgaa aaatctcaat
     6601 tattgacagg agaaacgatc aacccaggag atgtgttgct tggaatagca tctagcggga
     6661 ttcattcaaa tgggtactct cttgttcgca aaattttctt tgagcagcag cagttttctt
     6721 tatcatcaaa actgccagaa ttgaaaaaaa cacttggcga agaattgctt gagccaacga
     6781 aaatctatgt ttcttccttg cttccgctga tcaaagaaaa gaaaataaaa ggagctgcac
     6841 atatcactgg tggagggttt gtagaaaata tcccgcgaat gttaccagaa tctatggctg
     6901 cacaaatcaa acttggctca tggccgattc ttccaatatt cggctgttta caaaaatatg
     6961 gtgaaattcc tgagatggag atgtatgaaa tcttcaatat gggcatcggt atggtcctgg
     7021 cagtcgaaga atcgaaagta aaagaaatag tacacgaaat tgagcaagct ggcgaaaaag
     7081 tttatgaaat cgggaaagtg atcgccaaag aaaaacatcg tgtggtgttt ataggagaag
     7141 aacgatgaga atcgctgttt ttgcttctgg aaacggaagc aactttcaag cgctagccga
     7201 ttatctatcg aaaaaaggat tggaatcttc gattgactgg ttgttttgtg atcagcctga
     7261 agcatatgtt ttgaaacgtg caactgcgtt gagtgtaccg gcagattgtt tttcacctaa
     7321 agaatttgat tcaaaaaaag agtatgaaga agcaattttg cataaattga aagaaaaaaa
     7381 gatcgatttg atcgtattag ctggatatat gcgaatcatt ggaccggtat tgctgaaaaa
     7441 ttatgataaa agaatcatca atatccatcc gtctctttta cctgccttcc ctggtttgca
     7501 tggcatacgt gatgcctttg aagctggagt aaaagaaacg ggtgtcacaa ttcattatat
     7561 cgaccaaggt gtagatactg gaccaatcat ccggcaggaa aaagtgagaa ttgaacagga
     7621 ggacacgttc gattctttag aagaaaaaat ccatagagta gagcatcgaa tctatccaga
     7681 agtgattagt gaaattattg aaaatggagg ctatctgaaa tgacaagagc attgatcagt
     7741 gtatcagata aaactgggat tgtagcattc gcccaaggtt tgattgaaca aggagtagaa
     7801 atcatttcaa caggaggaac aaagcatgcg ttggataaag ctgggatcaa aacgctttcg
     7861 atcgaagaag tgacagggtt tcctgaaatg atggatggcc gtgtcaaaac acttcatcct
     7921 aaaatccatg gtggtctttt aggaagacgc gatctcccta gccatatgga ggcaatggaa
     7981 acggaaaata tccaaccaat cgactttgtt tgtgtcaatt tatatccttt caaagaaacg
     8041 attatgaaac cagatgtcga aatagcagaa gctattgaaa acattgatat cggtggtcct
     8101 agtatgctcc gtagtgcagc aaaaaaccat gaatttgtca cctctgttgt tgatccatct
     8161 gactatgaag aagtactttc agaattacgt cagtatgggc atacttcact ttctttcaga
     8221 caaaaactag cggcaaaagt ctttcgtcat actgcggcat atgatgcact gatcgctcaa
     8281 tacttaacgg attgggtgga agaaaaagaa ccggaaaaat tgacacttac gtatgaacga
     8341 aaacaaacgc ttcgttacgg tgaaaatagc catcaagccg ctgcctttta tcagtccgct
     8401 cttctggaaa aatattcgat cgcagcagca aaacaactcc atgggaaaga actttcttat
     8461 aataatatcc gagatgcaga tgctgcgcta cggatcatga aggaatatga cgagccaacg
     8521 gtagtcgcct tgaaacacat gaatccttgt ggtattggga cagcatctac gattttagaa
     8581 gcgtgggaag cagcgtatga agcagatcct gtttcaatct ttggtgggat catcgttttg
     8641 aatcgagaag tagatctgcc aacagcagaa cagatgcata agctgtttct agaaatcatc
     8701 attgcccctt cttatacaca agaagctttg gaattactgc aaaaaaagaa aaacatccga
     8761 ttactgacag tagactttgc gcaggaagaa aatcaaaatc gagaagaaac ggtctcagtc
     8821 ttaggtggac ttcttgtaca agatcaagat ctggcaatag aaaatgaaga agagtggaaa
     8881 gtcgtgacaa aacgtaagcc gactccagca gaagcaaaag cattagcgtt tgcttggaga
     8941 gctgtcaaac atgtgaaatc taatgcgatc gtactggcaa acgaacgtca gacagtagga
     9001 atcggagccg ggcagatgaa tcgagtcggt tcagtaaaaa ttgcgattga acaagcgcaa
     9061 gagaaaatgg aaggtgcagt tttagctagc gatgcttatt ttccaatgga tgattcggtt
     9121 gaatatgcag ccaaacatgg tataaaagca atcattcagc caggaggaag catcaaagac
     9181 caagattcta ttgatatggc gaataaatac gatctagcaa tggtctttac tgatgttcgg
     9241 cattttagac attagagagg agtcggataa atgaacattt tggtgatcgg tgcaggtggt
     9301 cgtgaacatg caataagtaa aaaactttta gccagtccga aggtggatac ggtgtattgt
     9361 gcgccaggaa atccggggat gacaaaagat ggtatcaatt gtgtcgctat cagtgagcga
     9421 gatcattcag cgttaatcca ttttgttaag aaagaggcta ttgattggag tatcgttggt
     9481 cctgaagttc ctttgttaaa tgggatcgtc gatgatttta tggcggaagg attgaaaatc
     9541 ttcggtccga caaaagcagc agctctgatc gaaggttcga aaagttttgc taaacaatta
     9601 atggatactt atcaaatccc gacagctaaa tccagaagtt ttgaatgtta cgaaaaagca
     9661 gcagcgtata tcaaagaaaa tggtgcgcca atcgtagtga aagcggacgg cttagcagct
     9721 gggaaaggtg tagtcgtggc taccacagtg aaggaagcgc tggatgcggc agaacaaatg
     9781 ttgaaccagc atcgatttgg ggatagtagc aaaaaaatcg tcgtagaaga gtttttggca
     9841 ggagaagaat tctccctttt ggcgtttgtc cgtaatacca aggtgtatcc gatggtcatt
     9901 tcgcaagatc ataagcgggc atttgataac gataaagggc caaatacagg cggaatgggt
     9961 gcttattcac cagtaccgca aatttcaaaa aagatgattg aaaaagctgt ggaagaagtt
    10021 ttaaaaccag cggctttggg aatgaaagaa ctaggacgct ctttcacggg tgttttatat
    10081 gcgggtttga ttgctacgaa ggaaggacca aaagtgatcg aattcaatgc gcgtttcggt
    10141 gatcctgaaa cgcaagtcgt tctttctcgg ttgaagagtg actttgcgca agtaatcgat
    10201 gatttattag agaatcgtac agtagagtta aagtggcagc aagaaggata caatgtaggc
    10261 gttgtggttg cagctgccgg ttaccccgaa gaatatgaga caggaatggt tctaccagat
    10321 tttctggaag aagagctttc tgtttactat gctggagttt cctcaaataa cggcaaacta
    10381 gttggagcag gaggacgtct ttatttagta gaagcatacg gtgagacgat caaagaagca
    10441 cagaaaaaaa tttacaccgc gttaatggat aaaacgacag atggaacatt ttatcgtaca
    10501 gatattggag aaaaagctgc caatagcgaa ctgatcgtga agtaaatcag ctgcttccat
    10561 ttataaaaaa tacaacaaac ataatcggaa gcgccgattt tagtgaagcc ttttcataaa
    10621 gagtgtggta cacttttgtt gtgtatataa ataaggagga gttcagatga aaaaaattca
    10681 attaggtact tctgatcaga aagcagctgc agtgatctta ggctgtatgc gtatcaacaa
    10741 tgcggaagat ccagtaaaag tgattgagac agcttatgaa aacggcattg atttttttga
    10801 ccatgcagat atttatggaa acggtgaatg tgaagaaatc tttgcagatg ctctagcaaa
    10861 aacatcaatc aaacgagaag atctttttat tcaaacaaaa tgtggaatcg ttccaggtgt
    10921 gatgtttgat ttttctaaaa aacatatcat tgaatctgta gaaaaaagtt tgacccgtct
    10981 gaaaatggat tatgtggatg ctttacttct tcatcgtcca gatacattgg tagaaccaga
    11041 ggaagtagct gaagcgtttg atgaattgga acggtcagga aaagttcgtt attttggcgt
    11101 cagcaatcaa aaaccaatgc aaatcgaatt gctgaaaaaa tatgttcgtc aaccattagt
    11161 agctaatcag ctgcaatttg gcttgaaaca tactggaatg atcgatcaag ggattcatgt
    11221 caatatgaca gatgaagcaa gtatcgatca tgacggtagt gtacttgatt attcccgatt
    11281 gcatgatatg acgatccaag catggtcacc ataccagtat ggattttttg aaggtgtatt
    11341 tatcgggaac gaaaaattcc ctgaattaaa ccaaacatta gaagaactag cagctaaata
    11401 tcaaacgaca ccaactggct tggcttctgc ttggatttta cgccatccag ccaatatgca
    11461 agtgatcgcc ggtacgatga acgtagggcg aatcaaggaa atcgctcaag cttcagaaat
    11521 taatatgtct cgggaagatt ggtacgaatt gtaccgtgct gctggaaaca ttttacctta
    11581 aagattgtca taagcaggtc aaaagggcta taaattaaaa agacagaata acttgaaagc
    11641 tgttttcagc ttcgagatat tctgtctttt tttattgcaa atggaaagag tatcattgta
    11701 cggatttcgt ttattagtta tttttgtttt taaggaaaag ctgtgtccga tattcttttg
    11761 gagaaatccc ttgttttttc ttaaataaat aactgaaata gttagggtca ttataaccaa
    11821 tttcaaaagc aatatctgaa atacgatagt ctgattgctg caataatttt tttgctaatt
    11881 cgattctttg ttctgtcaga taatcgatga atgtttggtt aaacgattga gaaaaaatcg
    11941 tactgaaatg agagggactt aatgcaactt gttgagcgac ccaagttaag gacatatctg
    12001 gatcggtaaa attttctttg ataaaatcca atgcatggtt caaaattggc tgatatttgt
    12061 tccttgaagg ctgtgagggc agagcagtta agaaagaaat gaacatataa actgtcgaac
    12121 ggtaaagcga gtcgtcggcg ctgattgcta agcgttgact ggtggatgtg caatgaacca
    12181 tttcttgcgg gattttcttt tctttcaggc agacatgctg gagtagctta gtcaagacaa
    12241 ataaacgata taatcgtgtt cgagttggtg tgccttgtgg tttcgtcaag tgttcgatgt
    12301 acttagatac ttcgtttttc gataatgaag acaaatcaag tgagaggtca aagtaaaaga
    12361 cagaatcaac tggaagtttc gcttcttgaa tcaaatcctc atagctgata atttgttctt
    12421 taagggaact ggcggtttca agtatcatct gcgtgatctc aaaagatgca ggtaattcgc
    12481 tgattctttc tgcgacagga ccaatggcga cagaaaaatt atttttttgt cccttttcta
    12541 attcatggac caacgtttgg gctacctgat aactggtctc gatcacattt tcttcaagag
    12601 aatcaactat taaaaatttg atgaatcgag aggaaacagc agagaagatc acttgttgat
    12661 tctccctaaa taaaaacttc aaataatcac tgagatgagc gtaatcttca aagtctgtac
    12721 tgacttggtt tgctgctaat aatacggtca tttttttccc tgctaaagag cgattgaaag
    12781 attcagcaag tttcaatgtt tcactgatcg taagtgagcc tttgaacaaa ccgttcaaga
    12841 aatgattttt tttcaattcg aaaacaagat cagaagaagt gtgcgtttct ttttgctgca
    12901 aatctaaagc agttactgct ttttctattg cttgtttcaa ttcgctactt ttaatcggtt
    12961 taagcagata atcatctgcc tgtacctgga ttgctccttt catataatcg aaatcgtcga
    13021 atccactaat aaatatgaga cgagtccaag gaagtagttt ccttgcttct tttgaaaaag
    13081 tcaacccgtc catgaaaggc atttggatat cagtcagaat gatgtcgggc tgtaagtcga
    13141 taattgaaga cagtgccatc tcaccatctc cagcttcgcc gacataagtg attggataat
    13201 aagaaccaag gacagttatt tgttcccgca agttattgcg aatgaggtat tcgtcttcga
    13261 tgataaaaac tttatacatg tttgtttcct ccaattgttt tgggagatag agggatcatc
    13321 agtgtgacag ttgttccttc tcggtatttg ctgtcaatcg tgataggttt ttgatcattt
    13381 ccgtaataaa gaaggagacg cttgtttacg ttgtaaagtc cgtagccgat actgaaatct
    13441 gaatcgatcc ctttggctaa ctctttacgt atttctgcca gtttttctgc agggatgcca
    13501 atcccgttgt ctataacttt gaattggatc atctcatcaa ttttgcatgt ggtaatacga
    13561 ataaatcctt tgtgacggac gtacttcgtt ccatggtata cagcattttc aatcaatggc
    13621 tgcaagatca tttttaaaat agaaacagga aaaagtgttt ctggtatatc gatcttatag
    13681 tcaagcatat ggccgtatct tatttttaag atgactagat aatcattgat atggctaatt
    13741 tctttttcaa gaggaatcca gtcttgtcct ttgcttaaag acgtacgaaa aaagccggaa
    13801 agtgcatggg tcatagtcag agcttcttca aagcagtctt gttcgatcaa agaaataatg
    13861 gcatccaaac tgttataaat aaaatgggga gtaatctgag cttgcaatac acgaacttca
    13921 ctttgtgcta aatggtattg tttcaaagcg ttctcccgta aagactggtt tagatcttcc
    13981 gccattttat tcatgctagc ggtaagtgtt tgtaattcca gtgtttccgg cagggttaaa
    14041 cgaaagccaa ggttccctga agaaagttgt tctgacatct cgatcagctg attgatcggt
    14101 tcttggacct ttctctctaa aaagcgacga ttctttttcg catagaaaaa aatggtacta
    14161 agaactccaa gttccactat tgttaataga atgagcgagc ggacaagtgt cgtatttttt
    14221 ttgcttgcta agtcgatctc cacacgaaca aaatcttgta agatatctga cagcagttga
    14281 gtgacagaat ctacctgatt gatgatctct tcattggtat ccataaaatc ttttgccaag
    14341 atattattga tcagctcgtt ttgataatct tccagtgtat cgatcgtacg tagcgataca
    14401 tctaacgtac taatttcttt aagtgtattt gtattatttt tgatctctcg aatatcattc
    14461 ctaagttctt ctaggatatt ttcctcattg aactcatcta cggttacttg gccagaaatc
    14521 aagtcccaca tactttccaa aactttttga tcaaccttca aagcaattgc atctgctttt
    14581 tggatatttg cgatcgtctg ttgataaatc aaaagctgtt gcgaatataa cagtatgctc
    14641 agtagcaaag ggataacagc aaatagaagc atggctttgt ttgcttgggc aaaaatctgt
    14701 tttatgctta aattttttgt catgatactt ctccagtcaa taatttctgg ttgggatgtt
    14761 agctatattc tgctgggaaa agacagtctc ggaaataaaa atatctttag gtaatgtttt
    14821 tcctgtttga atatttccaa aataacgagt aacggtattg gctacatacc agccgacatc
    14881 aggtttacac tcgactacac aattgacgat tcctgagcgt agcttctcga tcatatcttc
    14941 ttgtccatca atagttacaa tgatcaaatc ttctccaggt ttgattgatg tttcttttat
    15001 cgcagctaaa gcaccgtgag tcatttcatc actatggctg tataatacat cgatttcgga
    15061 taaatcattt gtttctaaat atcgtttcat ctggtctttt cctttcatcc gaataaaatc
    15121 accgacaatt cggtgaacaa tagtcatcgg aggtttatgg tcgatggttc catctttttt
    15181 tagggttggt ttacgattga ttgattccaa aaatccttcg gagcgtagct tggtcggtgt
    15241 ggagttctct gaaccagcaa gttctaggat tctgatttcc tgtttctttg aatttgtgaa
    15301 gtgattgctg acaaataaac ccgcccgatt tccttctgct ttgaaactgg ggccaatgtg
    15361 ggtgacgaaa agctcgggat cattcgtttg aatatgtctg tcgacaagta tgacagggat
    15421 ccctgctcgc tttgcttctt ttaatacaga gtcccacccg gattcttgca aaggagtaaa
    15481 aatgatcata tccactttat aggcaatgaa cgtccgtata tcttggattt gccgttcctg
    15541 attcatgtag ccatttcggt agagaacttg gtaatcttct ttttcaagcg cagtgataat
    15601 tgattcagta tgctttttcc gccagctact ctccgttcct gattgcgaaa aaccaacgac
    15661 tagtgggtca ggtgcttcct ttgtattagg tgtacacccc atcatttggt aagcgattac
    15721 aacaagggct aaaaaaaata aaacacgttt cactttaaat cactccatct ggatttgtta
    15781 gtactatctt atcagataaa agggaaaatc aaagtcaaaa ggaatcaatc gaaaaaaatc
    15841 caagaaactt aaaaaaatcc aagacaaaaa aagtacacct aaaaaattta aagtaaatcc
    15901 cataaaaaaa tcaatgttaa cgctttcttt attagctata ctcggtgtat caattgaaat
    15961 gggggataaa aaatgaaaaa caaatttaga aagattgttg ggactatcgc tattttgacc
    16021 gcaagcattc tattaagtgc gtgtggcaat tcaggatctg cagatgatag tacggggtat
    16081 gtaggaatcg ctatgccgac caaatcagca gaaagatgga tcgctgatgg gaacaacatg
    16141 gtctcggaat tagaaaaact gggttataaa acagatcttc aatatggaga agataaagta
    16201 gaaaatcaag tagcacaaat agaaaatatg attacaaaag gggtagatac acttgtgatt
    16261 gcttctatcg atggttcggc tttaactgat gtgttagcta aagcaaaaga agcagatatc
    16321 aaggtgatcg cctatgatcg tttactgatg aattcagaaa atgtcgatta ttacgcgact
    16381 tttgataatt ttggagtagg tgtatcgcaa gcagcttata ttgaagagca cttaggattg
    16441 aaagaaggaa aaggaccatt cacgattgaa ttatttggtg gctcgcctga cgacaacaac
    16501 gcactaatca attacaacgg agtgatgtct gttttacaac catatatgga caacggtcag
    16561 ttggtcgtgc catctggaca gacgagtttc agtcaaatcg ctacgcttcg ctgggatggt
    16621 tctacggcgc aagcaaggat ggataatctg ttaagcgcaa attatactga ccaaacattg
    16681 gatgctgttt tgtcgccata tgatccaata agtttaggaa tcatttcgtc attaaaaggc
    16741 gtggggtatg ggagtgaaag taaaccttta cctgtgatta ctggacaaga tgcgacagtt
    16801 gctggcgtta aatcgatcat tgccggggaa caaacacaaa cgatctttaa agacacacgt
    16861 atcttagcaa aaaatacgat tgaaatgatc aaagcaatca gtgatggaga agaggttccg
    16921 gtcaatgata ctgaaactta tgataatggg gtgaaaactg tccctacgta tttagcaaat
    16981 acagtatctg tcgataaaga taattatcaa gcagagctga tcgacaccga ttattataaa
    17041 gaatccgatc tgaaaaatta agaggaacca aacaaggaac taaagagatc taagtcagag
    17101 agaggataag aattatggcg gattgtattt taaaaatggc agatatcacc aaaaaatttt
    17161 ctggaatccg agcgttagat tgcgtgaatc tgatgattga acgtggggaa atccatgcat
    17221 tgtgcggaga aaacggagcg ggaaaatcaa cattgatgaa tgtcttgagc ggcttgtatc
    17281 catatggctc ctatgacggg gaaatctttt atgatggaaa gctgtgtcaa tttaaagatt
    17341 tgaaagatag tgaagaaaaa ggcatcgtca tcattcatca agaattagca ctaagtcctt
    17401 atctttcaat aaaagagaat atttttctcg gaaatgaaca agcagaaaga ggcgtgattg
    17461 attgggaact gacagaaaag aaaacatatg aactgctgaa taaagtcggt ttgtctatcg
    17521 acccgaatct tctagtatcc cagattggcg tagggcaaca gcaactagtt gaaatagcta
    17581 aagcattatc aaaatccgtc cgtctgttga ttttggatga gcctaccgct gcattgaatg
    17641 aagaagaaag cgcgaatttg ctgagattga tccgagagtt gaaagagcaa ggtgtaacct
    17701 ccatcattat ttcacataag ctgaatgaaa tcgtggatat cgcagatcga atcaccattt
    17761 tacgggatgg acagacgatt gagacactag aaaatgaaat gatcagcgaa gagcatatta
    17821 ttcgcggaat ggtgggcaga gatttagttg atcgttatcc tgaaagaaaa ccggatattg
    17881 gagaagttta ttttaaagta gaagactgga cggtctatca ccctcttgat cacgagcgaa
    17941 tcataaacga ccacatcaac ttgcatttga aaaaaggaga gattgtagga atagctggac
    18001 tgatgggagc gggcagaact gaattcgcta tgagtctatt tggacattct tatggaagca
    18061 agatatccgg acgtatatta aaggaagggg cagagatatc agttaagacc gttccttcag
    18121 ccattgcaaa cggactcgct tatgtctcgg aggaccgaaa atctttagga ctgaatctgc
    18181 tgatggatat tcgggaaaac gtgacgctga gcagtttgga taaaataagt caaaaaggag
    18241 tattagataa agaaaaagaa gtaactgagg cagaaaattt ccggaaaaag atgcgtataa
    18301 aaacaaactc catccatcaa attgtcagta gtcttagtgg tgggaatcaa caaaaagtcg
    18361 ttttatccaa gtggctgatg acacaacccg atattctttt tttggatgag ccaacccgtg
    18421 ggatagatgt tggggcaaaa tatgagatct acacgattat cgaagaaatg gcagcaaatg
    18481 gcaaagctgt ctgtcttatc tcttctgaac ttcctgaaat attagggatg tgtgatcgaa
    18541 tctatacgat gaacgaagga cgtattacag gagaagtctc gcgagaagat gcagatcagg
    18601 aagtcttgat gaaattaatg acgaaagaag aggtgggtta agttggaaca ggcaaaaaat
    18661 cttacggata aaaaagagaa aaaactaaat ttgaaaagta gagcagctga tctttttggt
    18721 cgctacagca tggtgatcat tttagcggga ctacttattg cgtttcaatt gatgacggat
    18781 ggtattttct ggcgtccatt gaatataact aaccttgttc tgcaaaatag ccatatatta
    18841 gtactagctg cagggatgtt attagttgtg ctcttaggtc atgtggattt gtcggtaggg
    18901 tcagtgatgg cgtttgttgg tgcaattgcg ggcatgatga tggtcaatcg ccaaatgaac
    18961 ccgtggatga cagttatcgc atgtcttgca gtaggcgggc tgatcggcgc atggcaaggt
    19021 ttttgggtag cttatgcagg gataccggcg tttatcgtga ctttagcagg attgctgatg
    19081 tttcgtggac tgacacaagt tgttctagga ggccaatctc tagcaccttt tccagctgtt
    19141 ttccaaaaaa tgtctacggg ttatttacca gacttaagcg aaggaagcag ccttcacttc
    19201 ttgacattga ttttaggaat gatcatcacg atcgtgttag ttgttggtca atggcgaaca
    19261 agaaatcgtc ggaaaaatca tttatttgaa gtggaatctc caacagcttt cttggtaaag
    19321 gcggtattta cagcagtcgt tgtactagga ataacttata tctttgcctc ttatcaaggg
    19381 tatccgatta ttttgatcat tcttggtttg atcgttgcag catatgggtt tttgacaaat
    19441 aaaacagtag caggtcgaca gatttatgcg acgggcggaa atcgaaaagc ggctgaacta
    19501 tcagggatca aaacaaagcg aatcacgttc tgggtattcg tcaacatggg agtcatggca
    19561 gctttagctg gattagtttt agctgctcga ttgaatgcgg caacacctca agcaggtaca
    19621 tcgatggaac tggatgcaat ggcggcagta tattttggtg gtgcttcgac ttccggcggc
    19681 attggaacaa tcatgggtgc gattgtcggt ggcttggtca tgggtgtatt gaacaatggc
    19741 atgtcgattt taggcgtcgg ggtagactgg cagcaggcaa tcaaaggatt gatcttgctt
    19801 ttagccgttg tgctagactt gtataataag aaaaaacgaa caacgtagga gaacgccggt
    19861 tattcagaaa aaagactgtg acaagacatt tgtcacagtc tttttttcgc taaaagcgaa
    19921 cattcattgt ttcgtttgta tagactaaaa ataatatatg tttttttacc attcgtataa
    19981 attctctttt tgctcttgat ttttttgctt aattgagtta aattacatag ggcgctaaaa
    20041 aaagccttga ttaaattaat aatgttcgtg ttttgctgga tgtgaacatc aggaggataa
    20101 tgtaatgaaa gtatttgatt acgaagatat tcaattaatt cctaataaat gtatcgtaaa
    20161 tagccgttct gaatgtgata caacggtcac attaggtaaa catacattca aaatgccagt
    20221 agtgcctgcc aacatgcaga cgattattga tgaaacaatc gcagaattct tagcggaaaa
    20281 tggttatttc tatatcatgc atcggtttga tgaagcagct cgaattccgt ttatcaaaaa
    20341 aatgaaaaag cgtggattga ttacctcgat cagtgttggc gtcaagaaag aggaatattc
    20401 ctttatagag aagttggcag aagaatcgct aaatcctgat tatatcacta tcgacatcgc
    20461 gcatggacat gctaactcag ttattgatat gattcagcat attaaaaaat atttgcctga
    20521 aacttttgtg attgccggta atgttggtac accggaagcc gtccgtgaat tggaaaatgc
    20581 gggcgcagat gcaacaaaag tcgggattgg tccaggaaaa gtatgtatta caaaaatcaa
    20641 gacaggcttt gggactggag gctggcaact ggcagctctt agatggtgtg cgaaagcagc
    20701 tcgcaagccg atcatcgctg acggtgggat cagaacacat ggcgatattg caaaatctgt
    20761 ccgttttggt gcgacaatgg tcatgattgg ttcattgttt gccggtcacg aggaatctcc
    20821 tggcgaaaca aaagtcgaaa atggaatcgt gtataaagaa tactttggtt ctgcttcaga
    20881 attccaaaaa ggcgaaaaac gaaatgttga aggaaagaaa atctggatcc aacacaaagg
    20941 atctttgaaa gatacactag tggaaatgca acaagacctt caatcatcta tttcttatgc
    21001 tggaggaaga gatctggaag ccattcgaaa agttgactat gtcatcgtga aaaattcgat
    21061 ttttaatgga gacacaatct aaaaaataaa taaaatatta ggatgttgtg aaaaagttgt
    21121 cctgcattaa gtaataagaa cagccaaaca aaaatagttc tttatatgtt ttgtttggct
    21181 ggaattatta tcgcagatac aagcttttga acatcattat tcagaataag ggactgtgat
    21241 aagatttttg tcacagtccc ttatgttttg caaaaaaagt ttttcttttt tctcgtaaat
    21301 tcggtaaaat caaaagaaaa aatagacaat agaaaagaga agcttatgtg ggaaaaagta
    21361 gagaaaaaac aaggaccgat ttatcgtcaa attatggaac agattatgag agaaatcgaa
    21421 aacggaagga tcaatcctgg aagtcaactt gaatcagaac gaaaactagg gcaacttttt
    21481 ggtgtgaatc gttccaccgt tgtccatgca ttggaagagc ttagggagct tggggtacta
    21541 acgagcaaac gtggcagcgg atggtttgtt aatcagactg aatgggggaa attcgctgtt
    21601 ccaagaatcg attggcggca aatgatctct cctcgttatg agcagacgga ctggtatgag
    21661 caaaaaataa gagaagcaaa gcagatccaa aaaacatcgt ttcttgattt atacgctagc
    21721 gagatgccag atgagctttt gccgaatttt gagtttcctt cttattctct tgaagaaatc
    21781 ttagcggaag aaaaagaaat ggatctttta ggctatactc cgttacgtaa caaaatcaaa
    21841 cggtatttgg aaagtaaatt tgaattggca ttttccccca accagcttct tgtgactggt
    21901 ggcggtcagc aagcaatctt tttgatttta caaacgattc tttcagctgg agaggggata
    21961 gctgtagagt caccttcttt tttttaccga ttacctcttt tcaaagcttc aggaacgcgt
    22021 ttatttggga taccgatgga tgaagaaggg atcgacttag aaaaactgaa agaatcgatc
    22081 cataaaaata aattgaaagc agtgcttatc aacccgaatt ttcaaaaccc tacaggaaaa
    22141 gtgatgagtc aaaaacgacg agaaaagcta gtagaattgt gtcgacagta tcggcttcca
    22201 attattgaag acgatgtatt tacggatctt tcatttctaa accaagaaga agtccttcct
    22261 atacgaacga ttgatccgga taatgtgtta tacgtcggtt cgttatctag ggttttagga
    22321 aaaacaacga aaatcggttg ggtgatagga cctgagactt ttatctcgca actagctcaa
    22381 gcgcaagaaa tgatggagtt ttcgatgaat atccttacac aaatcacagt ggctaatgta
    22441 tttaatgaag caattgattt gaaaatgcaa gatgtaagaa aaaagttgaa agaaaaaagc
    22501 cgactgataa gcgcttgggg agattcacaa tcgtttttca agcttcattc aattttaggt
    22561 ggttactatg cctggattac ttgggatggg aaaaaactag accccgaact agcagaaaaa
    22621 gtagtagata tgggtcttgg aattgcacca agtctacttt ttgggcaaga tataaatgga
    22681 atcagaatca attacagtag gctggatgaa aaccaaatac cgttgtttta ttcaaagatg
    22741 aaaattctag aaaagtggtt aacagaataa tttcacaaag taaatagatt aaagaatata
    22801 acagcttgga tttaaatttc aagctgtttc ttttttttcg gaaaaagaat acgatataaa
    22861 gaaactaaga aaaaaccatt atttgtacgt ccgttcacga tgtgtaaata aaataaatgt
    22921 ttgcaacaaa actgtataac accaacgttt ttaaatagaa acagatggtt gtaagtttga
    22981 ttagaaaata gaaaaaatgc agatgaaata taaaacgctt tccttattgt gattttattc
    23041 actaatgctg ttaatatgcg gattggcata atttcctttc atcgtgaaaa tttgtgcttt
    23101 tagcttgtat ttctcataaa tccatgataa tttattaatg aagacggtta aatagtgata
    23161 cagttttatt cactgtttca atcgcagaat gaagagattt tcttatagat gagagaggaa
    23221 tgtgtgacaa atggcaaaca aaaaagcacc gatcgacttc caagcactgc tagatgaagt
    23281 caatgcagat ttcccagtat atcaagcact tgatcaagat ggaaacgtag ttaacaaaga
    23341 tttagtacct gatttatccg atgatgaact cgttgaatta atgactcata tggtatggtc
    23401 tcgtgtatta gaccaacgtt caacagcgct gaaccgccaa ggacgcctag gcttttttgc
    23461 accaactgct ggacaagagg caagtcagct ggctagtgct tacgcatttg ataaagaaga
    23521 tgttcttctt ccaggttatc gggatgtacc tcaactagta aaacatggtt tacctttatc
    23581 tcaagctttt ttatggtctc gaggacatgc tgcaggtaat tcttatccgg aagaattgaa
    23641 agctctacca ccacaaatta tcatcggtgc acaatatgta caagcagccg gtgttgcatt
    23701 aggtttgaag aaacgaaaca agaaaaatgt cgtcttcact tatactggtg atggcggttc
    23761 atcacaaggt gatttttacg aagcaatcaa tttcgctggc gcttaccatg caaatgccgt
    23821 attttatatc caaaacaacg ggtatgcgat ctctacacct cgtgaaaaac aaactgcagc
    23881 aaaaacactt gcacaaaaag ctgtcgcagc tgggattcct ggtattcaag tcgatggaat
    23941 ggatccgctt gcagtatata ctgtatctaa aatggcacgg gaatgggcga tcagtggaaa
    24001 tggaccagtc ctaatcgaaa cactgactta tcgttatgga ccacatacac tatctggtga
    24061 cgatccaacc cgctaccgta caaaagacac agatgacgat tggcagaaaa aagatccatt
    24121 gatccgcttc cgtaaatatt tgacggaaaa aggactttgg tctgaagaaa aagaagaaca
    24181 agtcatcgaa gcaactaaag aagaaatcaa agcagctatt gctgaagccg acaaagtacc
    24241 aaaacaaaag gtttcagatt tcttgaaaaa catgttcgaa gtatctccac aatcaatcaa
    24301 agaacaaatt gcaatttatg aagcgaagga gtcgaaataa tcatggcaca aaaaacaatg
    24361 atccaagcaa tcacagatgc cttagcactt gaactagaaa atgacgagaa tgtcgttgtt
    24421 tttggtgaag atgttgggaa aaacggagga gttttccggg caactgaagg attgcaggaa
    24481 aagttcggag aagaccgagt attcgatact cctttagctg aatctggaat cgcaggattg
    24541 agtttcggtc ttgcgttaga aggatttcgt ccagttcctg aaatccaatt ctttggtttt
    24601 attttcgaag caatggacga agtagtagct caaatggctc gtacaagata tcgaatgagc
    24661 ggcactagaa atctacccat cacaattcgt tcgccatttg gtggcggtgt tcatacacca
    24721 gaattgcatt cggataattt agaaggtttg atcgctcagt ctcctggtat tcgagtagtg
    24781 attccttcca acccttatga tgcaaaagga ctattgattt cttctattag aagtaacgat
    24841 ccggttgttt tcctagaaca catgaaacta tatcgctcat tccgagaaga agtgccggat
    24901 gaagcttacg aagttccttt ggataaagca gcagttactc gtgagggaac agatgtatct
    24961 attatcacat acggagcaat ggtgcgtgaa gcaatcaaag cagcagacaa tcttgcaaaa
    25021 gaaaatatat ctgttgaaat cattgatctt cgtacagttg cgccattaga tgtagaaacg
    25081 atcattcaat ccgtggaaaa aactggtcgc gtagttgttg tccaagaagc acaacgacaa
    25141 gcgggcgttg ccgcgcaagt agtttctgag atctcagaac gcgctatcct ttcattagaa
    25201 gccccaatcg gacgagtttc tgcacctgat acagtcttcc catttggaca agcagaaaat
    25261 gtctggttgc caaatgcaaa agatatcgaa gacaaagtaa aagaaatcgc ggaattttaa
    25321 gaaaagaagg gacgaaacaa agtcatggct tatcaattta aattgccgga tatcggtgaa
    25381 ggaatcgcag aaggtgaaat cgtcaaatgg ttcgtcaaac caggagatac gatcaatgaa
    25441 gatgatacat tactagaagt tcaaaatgac aaatcagtag aagaaatccc gtcacctgtt
    25501 acaggaacgg ttaaaaatgt gattgttcca gaaggtaccg tagcaaatgt tggggatgta
    25561 ttagtagaaa tcgatgcacc aggacacgaa gacaatgaag gggacagtgg tgtagccgca
    25621 gaatcccaaa ctccagctaa accggctgct gaacccactg ttgatacaga atcagctgga
    25681 tcgtcaagcg aaggagtctt ccaatttaag ttaccggata tcggtgaagg aatcgcagaa
    25741 ggtgaaatcg tcaaatggtt cgtcaaacca ggagatacga tcaatgaaga tgatacatta
    25801 ctagaagttc aaaatgacaa atcagtagaa gaaattccgt cacctgtcac agggacagtt
    25861 aaaaacgtga ttgttccaga aggcactgta gcaaatgttg gggatgtatt agtagaaatc
    25921 gatgctcctg gacacaatag tgcaccgtca actagtgcgc catcagctga agcaccaaaa
    25981 gaaaaagtgg aaacatcagg ttcagcaagt gtcgttgaag ctgccgatcc aaataaacgt
    26041 gtattggcta tgccatctgt tcgtcaattt gcccgtgaaa aagatgtaga tatctcacaa
    26101 gtaactgcaa ctggaaaagg tggcagagta acaaaagagg acatcgaaaa cttcttggca
    26161 ggtggtccaa gcagtgcacc agcgaaatca gaagcgccag aagcggcagc accgaaagaa
    26221 gcagctcctg cagcagaaag caaaccagct gcaccagcaa aaccattcaa gtccaactta
    26281 ggagacttgg aagaacgtgt agcaatgacg ccaacacgta aagctatcgc taaagcaatg
    26341 gtcaacagta agcatacagc tccacacgtg acattgcatg atgaagtaga agtgtctaaa
    26401 ctatgggata atcggaaacg atttaaagaa gttgctgctg caaatggtac gaaacttact
    26461 ttcttgccat atgtcgtgaa agctttaaca gcgactgtta agaaataccc agtattgaat
    26521 gcatctatcg acgatgcaaa ccaagaaatc gtttataaac attactacaa tatcggtatt
    26581 gcaactgata cggatcacgg actatatgta ccaaatgtga aagatgcaga ccgcaaagga
    26641 atgtttgcta ttgcagacga aatcaatgag aaagcaaaat tagctcatga cggcaaacta
    26701 tctgcagaag atatgcgcaa tggaacaatt acgatcagca atatcggatc tgtaggtggc
    26761 ggttggttta caccagtcat caactatcca gaagtagcta ttttaggtgt aggaacgatt
    26821 gcacaacaac caatcgtaaa tgctgaaggc gaaatcgttg tcggtcgtgt gatgaaactg
    26881 tcattaagtt tcgatcaccg tatcgtagat ggagcaactg cgcaacaagc aatgaataat
    26941 atcaaacgtc ttttagctga tccagagcta ttaatgatgg aaggatgata aacaaatggt
    27001 agttggagat tttgctgtag aattagatac agttgtaatt ggtgcgggac ctggtggcta
    27061 tgtagctgcc atccgcgctg ctgaaatggg acaaaaagta gcaatcattg aaagagagta
    27121 tattggcggt gtttgtttga atgtcggctg tattccttca aaagcactga tagctgcagg
    27181 acaccattat caagagtcac tagattctga aatgtttgga gtaactagtg aaaacgtcaa
    27241 actagatttt gcaaaaacac aagaatggaa agaaaacaaa gttgtccata cgttgacttc
    27301 tggtgttggt ttcctattaa aaaaacataa ggttgaaaca atcgaaggag aagcgttctt
    27361 cgtagatgat cacacactac gcgtcattca tccagattca gctcaaactt attcgttcaa
    27421 taacgcaatc atcgcaacag gttcccgtcc aatcgagatt ccaggattta aattcggagg
    27481 acgtgtgtta gattctactg gcggattagc attgaaagaa gtacctaaga aatttgtgat
    27541 catcggtggc ggtgtgattg gtgccgaatt gggcggagcg tacgcaaact taggagcaga
    27601 agtaacgatt cttgaaggct caccacaaat tttaccaact tacgaaaaag atctagtaaa
    27661 attagtagaa gatgatttca agaaaaaagg cgtaacagtc gtaacgaatg caatggcgaa
    27721 agaagcagtc gataacggtg acagcgtgac agtgaaatat gcagtggacg ggaaagaaga
    27781 atccgttact gctgattatg tgatggtcac tgtaggtcgt cgtccgaata cagatgatat
    27841 gggcttagaa caagcgggtg tcgaagtagg agaacgagga ttgatcacgg tggataaaca
    27901 aggacgtacg aacgtaccta acatctatgc catcggtgat atcgttccag gggcggcatt
    27961 agcacacaaa gccagttatg aagcaaaaat cgctgctgaa gcaatctctg gcaaaaaagt
    28021 agctgtagat tataaagcaa tgccggcagt agccttcact gatcctgaat tggcttctgt
    28081 aggtatgacg atcaaagaag caaaagatgc tggtatcgaa gcaaaagcat ataaattccc
    28141 attttcaggg aacggtcggg cattatcgct tggtaaaaca gaaggattca tccgtctagt
    28201 tacgacgatc gaagataacg tgcttattgg cgcgcaaatc ggtggagtcg gcgcaagtga
    28261 tatggtctct gaattagctt tagcaatcga atcaggaatg aatgctgaag atatcgcctt
    28321 gacgattcat cctcatccat ctcttggcga aatcgtcatg gatgcttcgg aattagcatt
    28381 aggtttacca atccatattt gatttgaata atacaggcga aacgcaactg aaaaatcagt
    28441 tgcgttttgt tttttagaat tatcaataat attattatgt aaacttaaaa atatgacaac
    28501 ttcttggttt attaccactt cctatgctac actgaagagg aatatgaaat aggagagttg
    28561 aagatgcaag aatatcagta tccacttgat ttagattgga caacagacga aatggtcatt
    28621 gtaatgaaga tgtgggaaga tctggaacgt gcgaatgaaa aagggataaa caatgaagct
    28681 tttttgaaga cttatcagca gtttaaaact gttgtcaaat ccattggtga ggaaaaacga
    28741 ttgggacggg aatttgaaaa agcttccggt tattctttat atcgtacagt gcagcaagca
    28801 aaaaaaaatc caaacaaaac tttgagaatg aacgggtgag ataaatggaa cagatgattg
    28861 atcatatcaa gtcctggctt gaagaagctg gtgagaaaat caaatcttct caacaaacat
    28921 taacaatctc gcaaaaatca aatcgaacgg atctagtaac aaatgtcgat cgaaacatcc
    28981 agaattttct aatcgaaaaa atccattcct ttgatccaga ggcgaaaata ttggcagaag
    29041 aagaagggtg taatcaatta tcggatctcg atggaagagt ctttatcatc gatcctattg
    29101 atggcacctt gaattttgtg attgaagggg aaaatttttg tattatgctc gctgtttatg
    29161 aatccggcgt tggaaagctt ggtttcattt atgacgtgat gagaaatgaa cttttttggg
    29221 gtggaaaagg aataggcgtg tataaaaatg atgagccatt gcctagacca gcaaataaat
    29281 ccttatcgga aggcttactt ggtgtgaata gttatctttt cggtcataat aaatatggaa
    29341 tccgagaaat tgcggaaagc agcatgggga cacgtatgta cggatgcgct ggtcttgaac
    29401 tagtggcaat cttgaaagga aaccacattg cttatatttc aaaccttagc ccttgggatt
    29461 atgcagcggg aaatgtctta ttggaagagt ttggtatggt aacaagcggt ctttttggta
    29521 ctcctttgac atttgaaaaa agggaatact atttagcagg gacttcttgt gcatatgcag
    29581 aaatcgcaga ccttttgaaa aaagaaggct gaaaaaaagg tagaaatcat tcacaaaaat
    29641 gataaaaacg agcaaaagat taattttctc gaaaaaatga aaacatttta ctatatttca
    29701 tgaaaaaagt ctgctataat tagcagtcga gtaaaatttg ccctgtcata aagaaccaat
    29761 aaaaaaggag ttagttacat tgaattatag aaacgatatc cgtaacgtcg caattattgc
    29821 ccacgttgac cacggaaaaa caacattagt tgatgaacta ttaaaacaat cagatacatt
    29881 agacgcacat acgcaattgc aagaacgtgc gatggactca aatgcgctag aaaaagaacg
    29941 tggtatcacg attttagcca aaaacacagc tgtagactat aaaggtattc gcgtaaacat
    30001 catggatact ccaggacacg cggacttcgg tggcgaagta gaacggatca tgaaaatggt
    30061 tgacggcgtt gtgttggtcg tagatgcgta tgaaggaaca atgcctcaaa cacgttttgt
    30121 attgaaaaaa gcactggaac aacatatcac accaatcgtt gtcgtaaaca agattgacaa
    30181 accttctgct cgtcctgagc atgtcgtaga tgaagttctt gaactattca tcgaattagg
    30241 agcagatgat gatcagttag actttcctgt gatttatgca tctgcactaa atggtacgtc
    30301 aagcttgtca gatgatccag cagatcaaga accaaccatg gcacctattt ttgatacaat
    30361 tattgaaaaa atccctgctc ctgtcgataa cagcgacgaa ccattacaat tccaagtttc
    30421 attacttgac tacaacgatt atgtaggtcg tatcggaatc ggacgtgtat ttagaggaac
    30481 aatcaaagta ggagaccaag tagcattaat taaattagac ggaacagtta agaaattccg
    30541 tgtaacgaaa ttatttggtt tctttggact aaaacgtcta gagattcaag aagcaaaagc
    30601 tggagacttg attgctgtct caggtatgga agatatcttt gtcggtgaaa cagttactcc
    30661 tgtggatcat caagatgcgt tacctatcct tcacattgac gaaccaacat tgcaaatgac
    30721 tttcttagtt aataattcac catttgccgg tcgagaaggt aaattcgtaa ccgctcgtaa
    30781 gattgaagaa cgtttgatgg cagaacttca aacagatgta tccttacgag ttgaaccaac
    30841 aaactctcca gatgcatgga cagtttctgg tcgtggagaa ttgcatttgt ctatcttgat
    30901 tgaaaacatg cgccgtgagg gatacgaatt gcaagtatct cgtccagaag ttattgaaaa
    30961 agaaatcgac ggtgtaaaat gcgaaccgtt tgaacgcgtg caaatcgata caccagaaga
    31021 atatatgggt agtgttatcg agtccttgag cttacgtaaa ggtgaaatgc aagatatggt
    31081 ccatacagga aacggacaaa tccgtttgac attcttaaca cctgcccgcg gtttgattgg
    31141 ttattcaact gaattccttt caatgacacg tggttacgga atcatgaacc atacttttga
    31201 ccaatatctg ccaatgcttc ctggtcaaat tggcggacgt caccaagggg cgcttgtttc
    31261 gatcgataca ggaaaagcaa cgacttattc tatcatgagt atcgaagaac gcggtacagt
    31321 cttcgtagaa ccaggtacag aagtatatga aggaatgatt atcggggaaa acagccgtga
    31381 taatgatttg actgtcaaca tcacgaaagc aaaacaaatg acaaacgtac ggtctgctac
    31441 taaagaccaa acatctgtca tcaaaaaacc aaaacaattg acgttggaag aatctttgga
    31501 attcttgaat gatgatgaat attgcgaagt aacaccagaa agcattcgct tgagaaaaca
    31561 aattttagag aaaaatgctc gtgaaaaagc atctaaaaag aaaaaataat ctgtaaaagg
    31621 atgaagagag aaaccagctt gttataaaaa atagctggtt tctttttttg tccaactctt
    31681 ttctgtggag aagtcatctt tgtcaatgga cataaattca gaaaatacgc cgaaagacgt
    31741 ttaaaagact tttaaaaaac ttatttctag agagtttttg tttcataata agataatgtt
    31801 tcacgaaagg agatcaactt gtccttcgaa gaaaatcgaa gtaaaatggc aagagaaagg
    31861 agcgggaaga tgaacgactt attaaaacaa tactttggct atgatgagtt tagacctggt
    31921 caaaaagaaa ttatccagaa agtcattgat caggaaaatg tattaggaat catgcctacc
    31981 ggaagtggga aatcaatctg ttaccagctt ccagctttac tattagatgg gcttactgtg
    32041 gttgtgtccc ctttaatctc tttgatgaag gatcaggtgg acgcggcgaa tcaattaggt
    32101 atacccgcca cttttatcaa tagctcgtta gatggttacg aaacagctag acgcttccaa
    32161 gaaatcgata gacagcagta ccgtttactt tatatcgctc ctgaacgttt tatcatgccg
    32221 gattttatcc aagcaatgaa gcgatggaac gtccgtatga tcgctattga cgaggcacat
    32281 tgtatctctc agtgggggca tgatttccgc ccaagttatt tacagatggc gaaccagcta
    32341 gatcaactgc caaatcgtcc tgtaattgtt gctttgacag ctacagcgac tgtgcaagta
    32401 gctgctgaca taaaaagact tttaaaaatt ccagaaaaca accatattca gactggtttt
    32461 gaacgagaaa atctacgatt tcaagtaatt aaagatcaaa aaaaagaaca atatctaatc
    32521 gaatatttaa agatcaacaa aaatcaatct ggtatcattt atgcagcaac gagaaaagaa
    32581 gtagaccgtc tctatcattt gcttaaaaaa ttcgattttt ccgtgggtag atatcatggt
    32641 ggtctaaatg agaatgagcg aacagaaatg caagaagcct ttttatacga tcgcttgcag
    32701 ctgattgtag cgacaaatgc atttggtatg ggtataaata aaagcaatgt ccgttttgtt
    32761 atccattatc aaattcctgg ctctctagaa gcatactatc aggaagctgg tcgggcggga
    32821 agagatggtc tttccagtga agccatcctg cttttctctc ctcaagatat ccaagtccaa
    32881 aagtttttta tccagcagtc ccaaagagaa gaagggcaaa agcaaaaaga atatgaaaaa
    32941 ttaaaagcga tgacagaata cgtgtatatt gagtcctgtc ttcagcaata catcctaaac
    33001 tattttggcg agacaagcag tccgtgcaac cgttgtggta actgtttaga tgacagagaa
    33061 atagtagaag taacgacaga agcacagatg gttctttctt gcttaaaacg tatgggtgag
    33121 aactatggta aacaaatgct gatgaaagtc ttagcaggat cgaaagaaca aaagctgcaa
    33181 gctttaggtt ttggacattt atctacctat ggactgatga aaaaccaatc gcaaaaagaa
    33241 acgatgcagt taattgaata tttgatatcg aatggctatc ttctgaccat caatggtgag
    33301 tatcctgttt tgaaagtaac agaaagaggg atacaagtat tgaaaggaca agaatctgtt
    33361 tatcgaaagg aacccaagaa agtccagcag ctatcggatg aagaaaccga tacactattt
    33421 gaagtgctgc gggaactgcg aacggatcta gcatcagaag caggcgttcc cccgtatgtc
    33481 gtattttcag attccacatt gaaagaaatg agccgaatac gtccatcaag cagattggag
    33541 atgcttcaga taaaaggagt tggccaaagc aagcttgata aatatggcga agccttttta
    33601 tctcggataa aaaatgcgga ctctaacgtt ctggataagt agaaagaacg aatacgtaaa
    33661 aatgaataaa aacaactggt taaatctgtt ttttttgctc cttatgaaaa tcaaatatgt
    33721 tataattaag gaattagaat gggaggtaag cacagatgga ttctttgtcg aaaaaacttg
    33781 cgatccaagt attaaatgat gaagcagaac ggatcaaacg attaatccga aatcaaaaca
    33841 acagtctctg tatctcacaa tgcaaagcct tcgaagaagt ggtagataca cagatgtacg
    33901 gcttttcccg gcaagtcggt tttgctgtcc gtataggagt aatcggaaag aacgagggcc
    33961 agctgatgtt aagtgagcta gaacgagaat tgaatcagtt atatagtgag gtttaccaag
    34021 aaatttatga taaaaaagaa gttggcaagg aggaatagac ttgcctaaga aagtgaaaaa
    34081 aaggcatcta ttagactata gcatcttgat tccctattta attttatgtg tattgggatt
    34141 gatcatggta tatagttcta cgtcgtatct attattagaa aacggacaaa atccgtccgc
    34201 atcagtcatt aaccagagta ttttttgggt gcttagcttg attgctatcg cactacttta
    34261 taaaatgaaa acagatgttt tgaaaaacca gcgtttgatc atggcagcca tcgcagtttt
    34321 gacgattttg ctgctgattg ttgtgttttt tggtaaggag atcaatgggg cgaaaggttg
    34381 gctgcaaatt gcaggattct cgatccaacc tgccgaatac ctaaaaatca tttctatctg
    34441 gtacctgtct ctgactttat ctaaaagaca aaacagtgta caaaaagatt ttcttgggac
    34501 tgtgaaacgt ccacttgcaa tggttatcgg acttactgca ttagtcgcta ttcttcccga
    34561 ttttggtaat gcggcagtta tctttttgat tattttggtt ctgcttttag ccagcggagt
    34621 caattatgtg tatactttga ttgtaggagt aggaggcttt tgtctaagta cttttacgat
    34681 ctggctgatc aatatcacaa acggaaagat cttacccgga cgtttacagt atatctataa
    34741 tcgatttgct atttaccaaa atcctttctc agacgaatta aataaagggc atcaactagt
    34801 caacggctac tatgccatgt tcaacggagg actatttggc aggggattag gtaacagtat
    34861 ccagaaaaaa ggatttttac aagaagcaca aaccgatttt atttatgcaa tcgtagtgga
    34921 agaactggga gtgattatgg ggattttgat attagcgttg ctattcttta tgattgtgcg
    34981 cattgtcctt gtaggtatcc gttcaaaaga tccgttcaat tcgcttttgt gcattgggat
    35041 cggcgcaatg tttttgatcc aagtatttgt caatcttgga ggaattactg gcgttattcc
    35101 tttgacaggg atcacgttcc catttttaag tcaaggaggc tccagtttgc tgatgctttc
    35161 gatttgtgtc ggctttgtcc tcaacatcag tgcggatgaa aaacgcaaga gcttaggttt
    35221 ataataaaaa aagatgtagg agtggttcga tgaaaaaagt tttagttgct aacaggggtg
    35281 aaatcgctgt acgtgtattt cgtgcttgta cagaattagg aattaaaact gttggaatct
    35341 atgcagaaga agatgaatat tccgtacacc gtttcaaagc ggatgaagca tatttagtag
    35401 gacaaggaaa aaaaccgatt gatgcgtatc tagatattga agggatcatt tctatcgcga
    35461 aagaatgcgg agctgacgct attcatccgg gttacggtct tttgtcggaa aacttgaatt
    35521 ttgcgcaacg gtgcgaagaa gaaggcatca tttttgttgg acccaaactg catcatttag
    35581 atatttttgg agataaaatc aaagcaaaag ctgcagctat cgaagcgggg attgcttcga
    35641 ttccaggcac agatggacca atcgcttcta tagacgatgc cttggagttt gcgaaacaat
    35701 acggttatcc gattatgatc aaggcagctc taggcggcgg cggacgcggc atgcgtgtag
    35761 ctcacgatga aaagagtgca agagagggct acgaacgtgc gaaaagcgaa gcaaaagcag
    35821 cctttggtag tgatgaagtg tatgttgaaa aatacatcgc taatcctaag catatcgaag
    35881 tacagattct cggggatacg catggaaacg tcatccatct ttttgaaaga gattgttctg
    35941 ttcagcgccg tcaccaaaaa gtagtagaag tagcgccttg tgtctctatg aatgaacagc
    36001 aacgtcaaaa aatctgccag gcagctgtcc aattgatgaa atatgtcggg tatgtcaacg
    36061 caggtacagt agaatttctt gttgaaggag atgattttta ctttatcgaa gtcaaccctc
    36121 gcgtccaagt ggaacatacg atcacagaaa tgattacaga tattgatatc gtaacaacgc
    36181 aactgttgat tgctcaaggt ttggatctgc ataaagaaat cggattgcct cagcaagaag
    36241 gaattaaatt aaatggttca gccattcaat gccgaatcac tacagaagac ccgttgaata
    36301 actttttacc agacacaggg aaaatcgata cgtatcgttc acctggtggt tttggcgtac
    36361 gtctggatgt cggaaatgct tacgcgggct atgtagtgac accgtatttt gattcattgc
    36421 tagtaaaagt atgtacgcat ggtgctacct ttgaaacagc cattcagaaa atggaacgtt
    36481 gcttgaaaga atttagaatc cgtggagtga aaacaaacat tccatttatg ctcaatgtca
    36541 tcacacatcc tgaattccaa tcaggaaatg caaaaacaac cttcattgat agtacagcaa
    36601 cattatttga atttcctcga ctacgagacc gcggaaacaa aacgatgaaa tatatcggtg
    36661 aaattactgt gaatggtttt ccaggtatcg aaagtggcga aaaaccattt tatgaagaac
    36721 cacgtatgcc taaagatcta atcacaagaa ctgattacgt aacggctaag aatgtattag
    36781 atgcgaaggg tgccgatgct ttggtcgaat ggatcaaagg acaggaaaat ttgttgttga
    36841 cggatacgac atttagagac gcccatcaaa gtctgctagc aactcgtgtt cggacaaagg
    36901 atttcaagca gattgcacgt ttgactggag aaggtcttcc tgaactcttt tcaagtgaga
    36961 tgtggggggg agcaacattt gatgtggctt accgcttttt gaatgaagat ccttggcaac
    37021 ggttgagaaa aattcgttct ttaatgccta atacgttgct gcaaatgctt ttcagaggtt
    37081 caaatgccgt tgggtattct aattatcctg acaatgtatt ggtggaattt gtcaaagaag
    37141 cagcagcgca aggaatcgat gtatttcgaa tctttgatag tttgaactgg actccacaaa
    37201 tggaaaaaag tatccaagct gtacgggata ctggtaaaat cgcagaggca gctatttgct
    37261 atactggcga tatcaacgat ccaagtcggg caaaatacaa tgttcagtat tataaagaca
    37321 tggcaaagga actagaacaa ctgggtgcgc atatcattgc aatcaaagat atggctgggc
    37381 tgcttaaacc gcaggcagct tatcgtttga ttagtgaatt gaaagaaacg acagatctgc
    37441 caatccatct gcatactcat gataccagcg ggaatggaat catcacttat tctgctgctt
    37501 caaaagcagg agtagacatc gttgacgtgg caatgagtgc aatgagtggg aatactagtc
    37561 agcctagcat gagcagcttg tattatgcac tggtcaatgg tccacggctg ccagaaatca
    37621 cgattgaaaa tgcacagaaa ttaaaccatt attgggaaga tgtgcgcatg tattacaaac
    37681 cgtttgaaaa cggcttgaat gctcctgaaa cagaagtata tatgcatgaa atgccaggag
    37741 gacagtattc gaatctacag caacaggcaa aagctgtcgg attaggtcat cgctgggatg
    37801 aaatcaaaca aatgtatcat actgtcaact tgatgtttgg cgatatcgtt aaagtaactc
    37861 catcatctaa agtagttgga gatatggcac tatttatggt ccaaaatgat cttacagaag
    37921 aagatattta tgaaaaaggc gaaacactaa gtttccctga atctgttgtg actttcttcc
    37981 aaggagaact agggcaaccc gttggcggat ttcctaaaaa attgcaaaag attattctta
    38041 aaggcagacc tgcattgaat gaacgtccag gtcttttggc tgaatcagtc gacttcaacg
    38101 aagtaaaaaa agaattggca gaaaaaattg gctatgaacc aaaacaagac gaagtattaa
    38161 gctatttgat gtatccgcaa gtctttttgg actatcaaaa agcatataat caatttggcg
    38221 atgttacatt actggacaca ccaacatttt tccaaggtat acgtttgggt gaaacaatca
    38281 atgtacaaat cgaacgcgga aaaacgctta tcattcgttt agatgaaatc ggagaacccg
    38341 atatcgaagg gaatcgcgta ctgttcttca atttgaatgg acaaagacgt gaaatcacta
    38401 tcaaagataa ttcgatcatc agtacggtcc aaacccgatt gaaagctgaa ccgacaaacc
    38461 gagaacaaat tggagcaacg atgtctggtt ctgttttgga tgtattagtg aaaaaaggcg
    38521 ataacgttaa aaaaggtgat acgttgatga ttactgaagc gatgaaaatg gaaacggcca
    38581 tcgaagcacg ttttgacgga gaagtcgcac atgtatatgt gtcttcagga gacactattt
    38641 cgtctggtga ccttttgatt gaagtgactg agaaataata agcgaaaggt ggggaaacat
    38701 gaaaagactg ggtttgtttt ggctgattct gctattagtt attgtggcat tctacatgga
    38761 accagtcttg tttccgccaa aacttgaagt gaaggaaaac tctgatcaac aaatatcaaa
    38821 ccaaatgaca acgtggaaat accaggagct taaagcaact ggtttttcta cttatatcgg
    38881 aaaaccgatc gatcagctgg aaaaggattt tggccaagcc tatgatcgat taactagcgg
    38941 atttggtttt gaaacaagat attatgaaaa taaagctagt catctcacat ttgaagcgaa
    39001 catccaagac agcagagtca caactgttaa agtactgcaa acagggcctg ctgatatcgc
    39061 gccgttttat ttagggatga cgatgcaaga tcttacgaaa atcactacta tctatactaa
    39121 tttcactttt gagtaccatg atacagaagt tggaatcgaa ctaatggaag aggatatgaa
    39181 ttatcgtccg ctaattgctt ttgataacga cacttttgct attttatttt ttgatcaaac
    39241 aacaaacggc ctattttcag ttgtgtattt agataaagat agtcttttga aactattgcc
    39301 atatcaagtg tttggtgaag gccttccaca ttatcaagca gataaatcgg ctgattggga
    39361 atcaatcaat cgcgttaaag aacgaaaaag tacgacttta ttaaatatgc ttagaagaga
    39421 agacgaactt cccatataca atcaaacact tgcctttcaa aaccacagtc agctgctact
    39481 acatgatttt ttgacaaggc ctgaggaaat attgtcagag gaacgtatgg ctgattggca
    39541 aaaatcgcta ggcagtgctc aaacgacagt gaaattctca ctgacgaatg atgaattgga
    39601 gaagttaatc agtaaacaaa aattagaaaa tactagtggg ctatttattc atccggcgat
    39661 tgacgctact ttttcgtttt tatattggta cagcgatcct tacaaccatg accgtttcat
    39721 ggacccggga acggattctg taggcattgc tttttctaaa gaaaatatgt tagtcttatt
    39781 gcaagaagaa aacggagaaa gtagtgatag cagtgatcgt taacgaagag ctgtttcaac
    39841 tggaggatca atgcctccaa gtcgctgaaa tgataaaaaa gagtaaaacg atggcttctt
    39901 atcttgaaca taaacagtca atggaagaat ctgcaaaagt ttgccagttg aaagaagcgt
    39961 tcttgtctaa gaaagaagca tttgaaaatg tagcggcata tggtgagtat gcacctgatt
    40021 atcgtgaaaa aaaacgagct gttcgaaaag caaaaagaca gcttgatatg gatgagcatg
    40081 ttgcagcttt ccgatatagt gaaacacagc tgcaaagtct gttggatcaa attgtccaag
    40141 tacttgccga agaagtttct aatgaaatca aagtagatgc aggtagcccg ttttttgaaa
    40201 cgaaaaaaca ctttggatgc ggaggtaatt gtcatgcaat tagacaatag tgaatttgaa
    40261 ataacaaaac gacgcgggct gatcgtatgg gtctacagct taaaacaatt aaagaatctg
    40321 aaaaagttcg gcttgttgca ttatgtctca agaagaatga aatatgtcgt gctttactta
    40381 aatgaagaga cattggaaga aacagaagaa cgaatccgta aattacattt tgttcgaaac
    40441 gtagaacgtt cttaccgacc ggatatcgaa atgaattttg ccgaaaaaat aggaaacaaa
    40501 acagtattaa aagacgaagg tttcgaaatt gaagagctaa atacagaaat ccgattagct
    40561 gaacatcttt aaaaatctct tatgagcagt ttttaaataa aaaataactt ggataacgat
    40621 cgatttttga tcattgtcca agtatttttt tggtatacta gtaccagtac catttctaag
    40681 gagtgagtag atgcggataa tatcaggaaa ttatggcggg cgccgtttaa aaagtttagc
    40741 aggggcgaac accagaccaa ctacagataa agtaaaagaa tccatattca atatgattgg
    40801 accatatttt gatggagaga cagtattgga tctgtttgca ggaagcggtg gtttagctat
    40861 cgaagcagta tctagaggct gcagtcatgc ggtatgcgta gacaaaaatt accaagcgct
    40921 aaaaatcatc aaagaaaaca tcgaaattac gaaagaacca gagaaattta ccacaataaa
    40981 acttgatgcg gacaaagcaa tcgaacggct agcagcggag aaacaacaat tcgactactt
    41041 gtttcttgat ccgccatatg caaaacaaaa aataatcgat caaatccata aaatggaaga
    41101 actgggactt ttttctaaaa ccgcagttat cgtatgcgaa acggataaaa cagtcgaatt
    41161 gccagaaact gtggctggat tccatcaaat aagaaaacag atttatggca taacggccgt
    41221 aactatctat agaaaagagg gaaatcaatg aaacgtgcat tattcccagg aagttttgat
    41281 ccttttacaa aaggtcactt agatacggtg gaacgtgcgg ctaaattatt cgatgaggta
    41341 gtaattggtg tttttatcaa tacttcaaag aaaagtttgt ttcccccaga agaaagaatg
    41401 acattgatca caaaagctgt ttctcatctt cctaatgtaa aagtcatgca tcaagaaaat
    41461 caattgacgg tagaaacagc aaaagagatt ggtgcagatg cgttgatcag aggcatacga
    41521 agtatcaaag actttgaata tgaacgagag attgctcaga tgaatcatca tctatatgat
    41581 gaattggaaa ctgtcttctt attagcaaaa ccagaatata gtcacgtgag ttccagtatt
    41641 ttaaaagaag tactgcactt tggcggagat gtgagcagct acttaccgcc agtgatcaac
    41701 gaagctttag ctggaaagcg tgaatcaaat gaaagctaaa caatggttga aaacagtact
    41761 gattatcata tttggaatgt tgatcattgg atttgtagta gttcccttgc cgtattatgt
    41821 agaatcaccg ggagccacga tcgatctgaa agaactaatt acggtcaatg ataaggaaga
    41881 taaaggttct gggtctttct ctcttacctc tgttggtatc aggcaagcta caggtttctt
    41941 agctttaaaa gctaaaatga ccccttttga agaattgatc agtgaagaag aattgactgg
    42001 tggggcgaca aatgaagaat ataatcaaat gcaacagtat tatatggatt cttcccaaaa
    42061 tgcagcaatc gaacaagcgt taaaacttgc agacaagcct tataaaatgg aattcaaagg
    42121 cgtatatgtc atgagtgtag agaaaacatc gaatttcttt ggcaagcttt cagttggaga
    42181 tacagtaaca aaagtagacg ggaaaagctt tcaaagtaca gaagcattta tggattatgt
    42241 aaaaagccaa aaagttggac aaacaatcga aatcagttat ttgcataatg gtgaagaaaa
    42301 aacagcttct ggtgatctga tcgagttacc aacagataaa aaggcaggaa taggtatcac
    42361 gcttactgac cataccgaga tcgaatcaga tacagatgtt cgtattaatt ctggctctat
    42421 cggtgggcca tcagcgggat tgatgttcac tttagaaatc tatgaacaag tcactggtaa
    42481 aaacttgcga catggtaagc aaattgcagg aactggaacg atcaacagtg aaggagaagt
    42541 tggccgaatc ggaggaatcg ataaaaaagt ggcaagtgcg gataaagctg gcgtagagat
    42601 tttctttgca ccagatgata cgatttcaga cgatgttaag aaagaatatc ctgaaataaa
    42661 aaccaactac gaagaagcaa aagctgccgc taaaaaattg aattcctcaa tgaaaatcgt
    42721 accagtaaaa acagtacaag aagcgcttga ctatctagag aaaatgaaat gaaactaaat
    42781 aattaaagag gggttgtgac acgagttctg tcacaacccc tctttttcgt caaaaatctt
    42841 cacgataaaa ataaaaacaa aagaaaaaat tgacgtaatt agatgttgaa gggacgattt
    42901 tgccagagct cactgtttct tcaattttaa atgaaaggag taatgaatga tttttactgg
    42961 tcattctttg aaaaaagaac aatgatagaa aaaatcagca agaaaatact agcttcaccc
    43021 aaattgatca tttggatgtc tatgatagtt cttatctttt gtatcgcaag tggtttttta
    43081 ttatcaaatt tgctatttta tagagaaaca gaagagactg ctgcaaaaga aatactttct
    43141 tcgtttagtt ccagtggaga agatccatca gctgaaggaa acgatgtaga agaggatgct
    43201 cgtccaaagg tcatgtacac cgatatcaaa ggaagtgtga aggagcctgg tatctattcc
    43261 ttttcttcag aagaacgggt ctatgatgta ctaaagcgtg caggtggatt attagaagaa
    43321 gcggatagcg atcgaatcaa cttttctgcg aagatagaag atcagcaagt cctatatatc
    43381 cctgctgtag gtgaagagct gccagaacat cttgatcagt tggcatcctc ggaaggaaaa
    43441 cagcctacag cagattccga gcctcccaaa ataaatatca atacagccac tccatcagaa
    43501 cttcagcaga ttcctgggat cggatcagtc aaagcgcaag aaatcattcg atttagagaa
    43561 gaaaacggat ccttccagaa agtggaagac ctgcaggaga tttctggtat cggtgaaaag
    43621 acagttgaaa aactaaaaaa cttcgttaca attaaataga atgattcaaa atcgactggc
    43681 acgagcaata aatggacgct aatggatact aagaataatc caattctaag agcttggcag
    43741 gacgaggagg tagtattttt ggataggaaa tagcttgatt gttcgcaaag aaacattaaa
    43801 aaaaccaatg ctgaatgtct atctccaaaa taaaatatct gggattcata ttatgaatac
    43861 ggctgtcagc ggcaataaca gtcaagctct acgagaacgc tttgccaaag atgtacttag
    43921 ctatacagca gataaagtat ttattctcat tgggacgaat gatctagcag agcataaaca
    43981 actttctaaa gaaacgtacc aaaaaatctg cagtggatga tagttcagct gaaaaaagac
    44041 tatagttctg atcatgcttt ctttatcacg ccaccagcag tcgatgagac aaaacaaaaa
    44101 tatcggaata acaagttgat caaagaatat atctctgttc tcacagaagt agcaaaacgc
    44161 catgattgtg aagtatcgat ttttatacgg aatttcttga acaaatggat tcgaagaatt
    44221 tttataatgg gctaatggat gacggacttc atttcggcag tgaagggtag gatcttttgt
    44281 cagacaggat gattcgttat atttaaagaa tattttgttt aagcaatgag tactttttaa
    44341 tcaacttgaa aaaacggagg aatataaaac atgttagaaa aatcttcaaa agcatgcgat
    44401 acgaataaag aaaaagttac tgataagtca cataatgaac gcattccttg ggaccagtac
    44461 tttatggctc aggcagtact gttatcttta cgtagtacgt gtacacgttt agaagtagga
    44521 gcgacactcg ttcgagaaaa aaggatcatt gctggcggct ataatggagc agtcagtgga
    44581 gatgtccact gcatagatga agggtgttac gtcgtggatg gacactgctt gcgaacgatc
    44641 catgcagaga tgaatgcact cctacagtgt gcaaaacttg gtatcccgac ggaaggttca
    44701 gaaatctatg tcacacattt tccatgtttg gcctgtacaa aggctttgtt gcaagctggt
    44761 gtgaaaggga tcaattatct ccatgactat cgaaatgatc cttatgccca agcgttgatc
    44821 gaacaattag gtgtatctgt acaccaagtt gctttagact cacagcattt ttcaaaactt
    44881 caaaatgaat taacaggaaa acatgtctag cgttttagaa aggcatgttc gaaatcggtt
    44941 gatttttccg gcaattacgt cgatgattat ctgtttgttg tattacactg acaattgggg
    45001 ttatcgtttg cttcttgccg gaattttttt atggttttcg ctaaaagaag gacgttttat
    45061 cgcgtacttg tgtattttgt gtagcataac ggtatccatt tcttataggc tacaagagta
    45121 ttcattttta gaggaaaaaa caacatctgc gcaaattact gtatttacag atacgattcg
    45181 tgcaaatggt aattttttga caatggaagg aaggttatca gagaataaac aaaagctcca
    45241 gctttcttat caagtaaaca cagaagcaga attgaaaaca tggcttaact tccgaggaaa
    45301 gggaatagaa ttgactgctg aaggcgagtt catctctcca gcaaaaaagc ggaatcttta
    45361 taattttgac caagaagctt acttcaggaa ccatagaatt tctggacggt tccaaattca
    45421 aaagattgaa cagatcacca tgcaaaatca ctggcgaaac tggcttcaga gaaaaagagg
    45481 atcttttatc tcctttgtcc aatctgaatt tccgcaaaaa acaagtgtat atattaattc
    45541 tttattatgg ggctataaag atgcaggatt cagagaacca gaagaaattt ttagggagag
    45601 tggtttgctg catctgttca gtctatcggg tctacacatc caattttatt tagggtggct
    45661 gtattattta tttcgacgta tcggatggcc actacacgtc agtattattc cgttgagtct
    45721 actaactatc tgttatgttt ctattgcagg aagttctatt tctgttttgc gtgctagttt
    45781 gctgttttta ttgcgattgc tagtcaaatt gctgaataag cattattcca ccatggactt
    45841 atttgcagtt gtcttttggc ttcttttact atttgatcct cgatttcttt ttcatgcggg
    45901 tggacagctt agttttttca tgagtttttt gtttatcctg atttcttttg atggagattg
    45961 gttgaaaaaa acggcctctc acgtcctgtt tactatgatc acgatgccgt tgattgtatg
    46021 gcatttttat gagtggccta ttttaggtag tctttttaca ttactgattg caccggtatt
    46081 caagtttctt tttcttcctg gtgtgttatt tctcacactc ttcaatcgct ggctgccgga
    46141 aactttactt ttgctgatag aagagggatt aatcttattt gagcgaataa tcgatttttc
    46201 ttcagggtcg tctctcatta taggacgttt gccccttgtg ctatctggga tgtatatttt
    46261 cggattactg atttgtatgg ataggttgaa agaacaacct gtgaaacact tgttttatgt
    46321 tggtcttttt tcttttattt ttttgacttt gccattttta cgcttttctt caacgatcgc
    46381 ttttatcgat gtcggtcaag gagacagtat ctttttgcaa agtccttttc gaaaagaaac
    46441 gattttgatc gatactggag gtcagttaca ctttgaaaga gaaaagtggg cgcaaggtat
    46501 gatacgtcct cctgctgaaa gaaatatcgt tccatatcta aaaggtcagg ggataagtgt
    46561 aatcgataaa ctcatcttga cacacgacga tacggatcat gtgggagaat tacccacgtt
    46621 atctcagcat tttactatca aaaaaattta tatcggttgg ggcgctggac gaaatgagcc
    46681 attacaaagg catttatctg aagctcaaaa aaatggtact gagatcattg aaatcaaaca
    46741 tggggacagg atcagcggtt attatgatct ttatgtattg actccttttg aaaagggaga
    46801 gggaagaaat gaagattcga ttggtctatg gatggaatat aacaataggc gctttttatt
    46861 tttaggagat ttgaatcaag caatggaaaa acaattgctt ttgatttatc ctaatctgaa
    46921 agccgatgta gtcaaattag gtcatcacgg tagccgtacg tcaagtaaca cagattttct
    46981 ttcccatatt gaagcaaaac atgggattat atcctgcggc gtaaataatc gttatggtca
    47041 cccgcacagc gaagtattgg agacactaga agaaaatcag ataaaaacat ggcgaacgga
    47101 tcaacaagga atgatcacct atcgctggca tccagttttt catcctcatg ggctagtgga
    47161 aacaatgata gactagtaat tctcatctgc tcatggtagg ataatttttg aaagtggtga
    47221 gtaatttgag tatacaagca gagttacaaa aaatacgtaa agaaaaactt gcatcttgtt
    47281 acttgatttt aggaacagaa aagtttctcc aagatcaagt tcggacagaa attgtcaaaa
    47341 aaatccaatt agagggcgaa gatgacttaa attttttaag ttttgacatg gaaaatgcaa
    47401 gtttagatga ggtagtagct gaagcagaga cgttgccgtt tttcggagat caacggttag
    47461 tattcgtaga gaatccttat tttttaacag gtgaaaaagt aaacaatgga atcgaacaaa
    47521 atactgattt attgacggct tatttgaaag aaccattaga atcgactgta ttagtattct
    47581 ttgcgccata tgaaaagttg gatgaacgga aaaaagtaac gaaacaattg aaaaaaacag
    47641 caattatcat caatgtccaa cagttgaatg aaaaagaagt acgtcaatat ctgatgaata
    47701 ccttagagaa ttcctcaatc aaaatggaac gaagtgcaat tgatttattc ttgaggttga
    47761 ccgacttaga tttatccaaa atgatgagag agttacagaa attggtcctt tatggacaaa
    47821 atcaacagca aatcacggta agagaagtag aagaattagt tcctaaaacg ttagaacata
    47881 atatttttga catgacccaa tatattttaa aagggaagac ggaacaagct ttgcgtttat
    47941 acgaagattt agttatgcaa ggggaagaaa caatcaaaat taatgcgatt ttgctttctc
    48001 aattacgttt atttttacag acaaaatttc ttgtaaagat tggttatcag caggcaaata
    48061 ttgctgaaac attgaaaatc catccatatc gtgtaaaact tgccatgcag gaagtaaaaa
    48121 aattcgatga acatttgctg gtacagttgt ttgatcaatt agttgagatg gattatcaaa
    48181 tcaaaacggg acaaatcgaa aaagaattaa gttttcaact attcgttttg cgcacagggc
    48241 agttgttaag aaatcgataa gaagaaagac gagggcaaag catgcgggaa ggtcgtttgt
    48301 ttttgtcctt tttttgacaa ataaaaaaat cggccgaagc cgattctttt atttagcgat
    48361 ttttttgctt aaacgagatt tgtcgcggtt agctttgttt ttgtggatta gaccttttga
    48421 ttcagccata tcaatagctt taacagcttc tttatataac gcatctacgt tgtcagcacc
    48481 tgaagctaca gcatcttcaa attttttgat tgcagtacgc atagcgcttg tttgagatga
    48541 atttttcaca ttagcgtttt cgcttgtacg aacacgtttg attgcagatt caatgtttgg
    48601 cattagtttc acctccgata acttaagttc ttacgcgtgt taccgcataa ttcaacattc
    48661 attattatac ctaaaggcag cgtgctttgc aatatgaaca tgacaagttt ttttccttaa
    48721 cagtctttta ttaggatttt ttttcagtaa aaacggatag tacaagctga aaaaaatcaa
    48781 aaagacgcta ttgtgggagg caatagcgtc aaaccaaact agatttttat ttatctattt
    48841 aaacaaagtt tgaatgggaa tgtttggtac taagttatta tataacaaag agaaccgttt
    48901 gcaaagtttt ttttgaaaag ggatacgatt ccctgttgtt ctttgttttt ctattaagaa
    48961 actgcagtta ttttataacc agtatccttt gatcagtaaa ggctattctg gtgtaccgat
    49021 tattttaatg tattcatcga tattttttat caacattttt tttatgacca actggttccg
    49081 acggttccat ttgccactta cttccagcac atatttattt aggggcaaac gtaagatata
    49141 ttttgccaaa tagcgatctt taagcaggcc attgatcaca cggtcctcaa gctgcaagtt
    49201 gatcccagtc agcatcattg gctgttcttg taaaacgtac gtatcaatta aaagaccttc
    49261 aaaagtttcc acaagcgtct tcctttcttt tcaaagtaac ctgaaaacag gcactaattc
    49321 ttccattttg atattcgttg aagtggatgc gatcattctt tcttttgtcc actgtaatct
    49381 agtataacaa aaaagagcag aagagccaaa aagaaaaaag agcatcgaat tctataggaa
    49441 gtctcattgg cacggcctaa attattacaa aacattgatt aaaaaaagcc cctgcatcgc
    49501 aggagcatcc cctatatcgt tttaataggt caatcaaaaa gcagtatcaa acacattttg
    49561 tatcaaatca ggaaataata gataagctaa gcccagaatc aaaagtaccg ctagaagaaa
    49621 ccagccgatt gttcctatga aatactttaa tttttcgaac attgtatcac ctcgttgtca
    49681 gtatatcacg gatcagtaaa ttgggggtgt taagaatctc ctaaaataga caaaatttgt
    49741 tctattttcc taaagcaaat acttgtaaga tacagtaagt gataccagaa gcaatgaccg
    49801 gtccggcggc gattcctctt aagaagacaa cacctaaaat cgtgccgaaa acaagtgcaa
    49861 cagtgatttg tggatcagaa gcaatcaatc ctacaccctt ggaagataag acagccacta
    49921 gcccaccgca aaaaacagct acccagccaa taggggattt aaaggcttct aatagatcac
    49981 gtagaccgat ttctcctgtt gcgataggga ttagaatagc cgctgtgatg atcgtcaccc
    50041 caatattgat tcctttgcct tgaagccaag ggaaaaagga acgggaggct ggtatgagct
    50101 tcataatcaa aacaaaagct gccgctatca tcagactttg atttttagct aaaattgcta
    50161 caagtaaaat aattcctaaa aaaagccaac tttccatgaa atatattcct cactttcttc
    50221 gaaacaatca taacatgttt ttagaaagtt acaaaagtag gaattcatcc ttcaagacct
    50281 attcataagc tgtttttttc ataaaataaa caaaatcata aaaaaacact ttgcttattt
    50341 gacagaagac agccgcgctt tgtatagtgg acaagactta catttttttg aagaatcaga
    50401 aagatcaggt aaaggtctta gtaaacgcaa gccattcaga ataaccaata ttgtgcttcc
    50461 ttcgtgtcct acaactccaa gaggtagatt taaaaattgc aggaagttag aagcaatcaa
    50521 caagagaata acaagaatcg aaaaaataat attttgtttg atgatccgcc gcatttttaa
    50581 agatagccga tgactgtaga caaatttatt taagtcgctt ttcattaaga cgatgtctgc
    50641 gatatccata gcggcatctg tcccttgccc catagcgaca cctaaagaag cggctgctaa
    50701 agcaggcgca tcattgactc catcaccaac catcgcattt acttggtaaa gttcattctc
    50761 ttttttgact agttgtgttt tttcttccgg agtacagctt gcatagtaat gttcaatccc
    50821 tacttgttca gcaatggcct ttgctgtgcc agaatggtcg ccggttatca tacttgtatg
    50881 gatgttttgg gatttaaagt aggaaattac ttgttgggta tttgcttttg gaatatctag
    50941 cagacctaaa acagcaatta actgctgatc tttagaaaga taaatcacgg ttttgccttg
    51001 attttccaaa cgttcgatca tttccgcaat ctctttgctg attatcatcg tctcaggatc
    51061 atatgcgtgc ttgccaactt tccattgcgc acctaaatag gtagtttgta atccaaaacc
    51121 agtaatttct tctattggta agtattggat ttcttcaggt attgtgcaat cgaaatattg
    51181 caaaatcgca tgagcaagtg gatgcgtcgt tttttgttcc atagcaacaa gaagttgttg
    51241 tgccaaatcc ttttcatcaa agaaaaagct gtcagttaca actggttttc ctttagtgag
    51301 cgttcctgtt ttatcaaagg caatcgcttt taattcagaa agcttttcta aatggatacc
    51361 gcctttgatt aaaatcccat tttttgcaga atttgaaaga gcagctagag aagctggtgt
    51421 agcagatgcg acaagcgcac aaggagaagc cacaactaat aataccattc ctcgataaaa
    51481 gctttcatcc caactccaac ctaggaaaaa gtgggggaga aggatcatta gaggaacagc
    51541 aagcaaaatc aattttacat aattattttc gattcgttcg ataaatgaag ctgtttgagt
    51601 tggcgtattc tgcgcttctt ctactaattg gataatctta gcaaagacag tttcggaact
    51661 cgtttttgtt actcgaatcg tgatgggatt tccttgattc agcgttcctg catacatctc
    51721 atcgcctaaa tatttttcta caggcacaga ttcaccgctt aatgcagact catcgatcgt
    51781 tgcctgtgtg ctttctaaaa agccatctat cggaacagct gctcctttag cgacaaatac
    51841 caagttatcc acctttagtt gagaaacatc tacttcttgc atttgtccat tttcttttaa
    51901 taattgggct ttttgtggtt gaagattcat caaagcagta atttcttttt gacttttatt
    51961 agttgtgtat tcctctaatg caccgcttaa acaaaagatg aatgtcaaca ttgctccttc
    52021 aaagtaatta ccgatcaaac aggcaccaat agcagctaaa gccatcaata aatccacatt
    52081 cagtgtccga tcattccaca attctttcaa gccttccgat gtttgtttat atccaccgat
    52141 gataatggca ctgatataaa aaagtggggt gatggtaaga gagaatcggt cgaagataaa
    52201 accgaagatc ataaataaaa ggcagccgat tgttgctgca aaagcttttt tctgattagt
    52261 catcgttatt agacctcctt gtcaaaacaa ggatagcata ataaaaatgt aattgataat
    52321 aataacagct aaatgagaac gataatggtt atcatttggt gattaagctt gatgttgttt
    52381 ttattattta taatgattat tattaaagaa aataaaaaac cagaacattt ctcaaataag
    52441 agaagtgttc tggttttttc tacattgcaa taaaccaata accaatcaaa atgataccaa
    52501 ggataatacg ataccagcca aaagcggtaa agtcgttttt cttcaaatag cttagtaaga
    52561 atttgatagc taagacggaa accacaaaag atacgaatgt tcctacaaga agaacaacag
    52621 tttcttccat tttgaatgaa ttcccttcag ctaaatattt gacgatcttc aagccgcttg
    52681 cgccaaacat gacaggaatc cctaagaaaa atgaaaactc tgtagcgaca aaacgcgaag
    52741 caccaatcaa gatagatcct aggatcgttg cgccagaacg ggatgttccg ggaacaagtg
    52801 ccaagacttg gaataaccca acaagaagag ctgcttggta cgtaaagtca ttcagagaag
    52861 tccaacgagg tgttttgttt ttgttgcgtt tttcgacaat aataaaggca ataccgtaaa
    52921 cgatcaaaac aatggcaact ggtaagaact tgtggaaatt tgcttctaac caatcatcca
    52981 aaggcaaacc aatgatgatg gctggtatgc aagcaacgat cactttaaac caaagtgtcc
    53041 acgtatcttt tttttctacc gttgatttac ttggagaaaa tgggtttaac ttgtgaaaat
    53101 aaagaacgac gacagccaag atcgccccta attggataac gacattgaac atcgacataa
    53161 attgtgaact ggcatccagt ttgatgaatt catctgctag gatcaaatga ccagtactac
    53221 tgatgggcag ccattccgtt attccttcaa taataccgag aatcactgct ttgataatat
    53281 ttgcaaaaaa cataaattcc ttccttccca attaagatac atcttatagt ataccgttat
    53341 tttttgagaa acccaatctg ttttttaa
//
LOCUS       DAFKHN010000012        52409 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFKHN010000012 DAFKHN010000000
VERSION     DAFKHN010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.012"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            48..1388
                     /locus_tag="LY912_000686"
     CDS             48..1388
                     /locus_tag="LY912_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6954403.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1583..2026
                     /locus_tag="LY912_000687"
     CDS             1583..2026
                     /locus_tag="LY912_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBM6954404.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2288..3706)
                     /gene="nhaC"
                     /locus_tag="LY912_000688"
     CDS             complement(2288..3706)
                     /gene="nhaC"
                     /locus_tag="LY912_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBM6954405.1"
                     /translation="MEKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKKYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDILEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4110..5333)
                     /locus_tag="LY912_000689"
     CDS             complement(4110..5333)
                     /locus_tag="LY912_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBM6954406.1"
                     /translation="MTTTLSTNQLKDLIQYRLPEYQALALAIHDHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTGFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDEIGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDAALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAALSTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSEKGLASIAIAAELLANTALDLLREPKLLEKIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5365..6204)
                     /locus_tag="LY912_000690"
     CDS             complement(5365..6204)
                     /locus_tag="LY912_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBM6954407.1"
                     /translation="MKKIIRFAVITFVAIIWLAGCSQGKAATTEKKETTVKLGIIGED
                     TDVWDDVKDRLKKENIHLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNEEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENKKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDEHARPYVNIIVARKEDEDNKTYQKIVDAYQTEETAKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6221..6901)
                     /locus_tag="LY912_000691"
     CDS             complement(6221..6901)
                     /locus_tag="LY912_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954408.1"
                     /translation="MTEFFKTYLPNVYLIPDEFIEATKQTLYMSFWTAFIGGIIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILVLVFLSQFISN
                     QLIKKVTH"
     gene            complement(6903..7976)
                     /locus_tag="LY912_000692"
     CDS             complement(6903..7976)
                     /locus_tag="LY912_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6954409.1"
                     /translation="MIELRDISVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEAGK
                     IIEKGSSIQIFSHPEEELTKDFIRTATHLDQALETISAHAAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKVTILQKNELDNRIKVIEGGN"
     misc_binding    complement(8035..8273)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(8316..8549)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8626..9297)
                     /locus_tag="LY912_000693"
     CDS             complement(8626..9297)
                     /locus_tag="LY912_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBM6954410.1"
                     /translation="MKGAIFDLDGLLVDTERTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVQAAGSPEKVQEVRAKREEYFYQQLTSGAIQLKPYAKEILTDLKERHM
                     KLGIATTTVTKRATDILDHFQLADYFDTFTFGDEVSENKPSPVPYLTALERTGLEALS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYSVEEKEKLNLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(9375..12053)
                     /gene="mgtA"
                     /locus_tag="LY912_000694"
     CDS             complement(9375..12053)
                     /gene="mgtA"
                     /locus_tag="LY912_000694"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBM6954411.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASPNGLS
                     EEQIERSRETYGENAISYGKKTPFIIEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGEYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNDTLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEAAETLDTDTINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVAPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELITGEKISEMNDHELAQVAEEHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKIPFIQSNATFAMLVITTLGIIVGSVLPFTGFGAELGLM
                     PLPGNYWLWLFITVVAYLALVTAVKKIYIRRFQELL"
     gene            12713..13150
                     /gene="ndk"
                     /locus_tag="LY912_000695"
     CDS             12713..13150
                     /gene="ndk"
                     /locus_tag="LY912_000695"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBM6954412.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFATMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKGADAVPGTIR
                     GDYALPGTENIIHASDSRDAATKEIARFFPPFDTNKPSEKAAK"
     gene            complement(13172..14038)
                     /locus_tag="LY912_000696"
     CDS             complement(13172..14038)
                     /locus_tag="LY912_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6954413.1"
                     /translation="MYDGELIKKLRVNKKLTQTQLAEGICSKTSLVGIETNSVKKVSF
                     GTLKSFLERMNMTLAEYEWIRNQLDEPKKLKKKRRMLDRIQEDSFDPYKEIANNRRHY
                     KKTEDLYYLVLNLHMSKKTEVSETEFEFLRYECRIIEEYLMQVPEYGQFEVSILADFP
                     WIFSDRFIENNYLKIKKRMRRIAQLNNHEQYLFTFLTNLTLFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKSENHQEFFAVIEYTLGKNQRNSL
                     EKKLLAIAKPSS"
     gene            complement(14272..16350)
                     /locus_tag="LY912_000697"
     CDS             complement(14272..16350)
                     /locus_tag="LY912_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBM6954414.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPATLGQTEGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTIL
                     YPVTGTNAEQ"
     gene            16843..18060
                     /locus_tag="LY912_000698"
     CDS             16843..18060
                     /locus_tag="LY912_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBM6954415.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETREKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEASPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(18519..19142)
                     /locus_tag="LY912_000699"
     CDS             complement(18519..19142)
                     /locus_tag="LY912_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954416.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWEEYKLTANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLVVLLLTHDGDKVARLKNGKVVTAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     ASSQKNESTELSPSDSGSGQTITGNEENQASIITNESSEGQYQTYGQ"
     gene            complement(19298..20695)
                     /locus_tag="LY912_000700"
     CDS             complement(19298..20695)
                     /locus_tag="LY912_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBM6954417.1"
                     /translation="MKRYQFPKNFWWGSAASGPQTEGRISGDGKGENIFDYWYKNEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HHYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFQLFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKAYHEMDQSGVI
                     GIILNLTPSYPRDESNPEDVKAARIADAFFNRSFLDPAVKGEFPSELIERIKELDLMP
                     EIHPDDLTIIKENTVDLLGINYYQPRRIKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEKGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDRNGFEA"
     gene            complement(20717..21688)
                     /locus_tag="LY912_000701"
     CDS             complement(20717..21688)
                     /locus_tag="LY912_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6954418.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMEKISEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISNRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHAIDGLIVFLSEEEWSGFEMLTKMSIPVVALNCPGGPAGIDTIVVNDR
                     ESVAKVIAHHGGQGHKTIGFIAAAQTDYVARERLAGAKEAVQKDPSIHLEIFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            complement(21695..23995)
                     /locus_tag="LY912_000702"
     CDS             complement(21695..23995)
                     /locus_tag="LY912_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="HBM6954419.1"
                     /translation="MYDYPYQNPKLTIRQRVEDLLSRMNIAEKVGQVNQHLYGWECYE
                     KNGDKIELTEKLKEHVKWGGGLGALYGLFRSDPWSKTDYKNGIPAKESWKVANLVQEY
                     VLQHSRWKIPVLLVEECPHGHQGLDGISYPTNIGRGNTFNVALLEQSSRLMAKELAAK
                     GVHLALVSTLDLAKDPRWGRTEECFGEDPILSARFSEAVVRGFQGEIISEKVSFLDQT
                     VEEINKKKDQIGVVLKHCIAQGEALGGHNSGTVTIGRREFSDIYGPLLKSTRNAVGVM
                     AAYNDIDGIPCHINRALFEQTLRKEIGYQGIVMADGVALDRLSDVFTDKKTAAAYALA
                     AGIDLSLWDETYTKIAEAIDNQVVDEKLLDQAVRRVLSVKFLLGLFEQPFANDPKEYW
                     DHLMEESEHLNLETAKESITLLKNDGILPLDQQVKNIAVIGPNAHDVYHLLGDYSAPQ
                     TEDRLKKKIVQEIKTEFPQSKVSYAQGCEVRNQEDQEEKLLEAVTLAQNSDVIIAVLG
                     GSSARNFDMEFLRNGAVSSKGINMDSGENVDVASLSLGGYQEQLIEQLYQLGKPIITI
                     LVQGRPYDLMKIESFTNAIATAWFPGQEGGKAIAQMISGRNNPSGRLSLSYPRNSRQL
                     PVYYYQRAASKQENYYDLSGSPFYPFGHGLSYTTFEYSQMEVKTDIDKVIISIKVKNT
                     GSVSGKTSTLVYVRLIDGVVIQRTKLLKAFRKDELRSQEERLLVFELTSEDFSYMDID
                     DKRHYAKKAVIMVEQQEKEIKCNWQE"
     gene            complement(23997..25322)
                     /locus_tag="LY912_000703"
     CDS             complement(23997..25322)
                     /locus_tag="LY912_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6954420.1"
                     /translation="MKVVDRLSEKMLPIVSKMSSQRHLLAIRDSFIVTMPLVMAASVM
                     VLLNALIFSNATVQRILDLSPLAELASIVNNGTMSILAIIVCYNIGWNLATHYIQTGV
                     IDDPSFSPVHAGILSTAVMFILMSLSSTVTLMDGNTAEATGVFLQSLTSSSGLATAMI
                     AALVSTELFIKLAKMKSFKIRMPEGVPPAVAASFNSLVPEIVVILFFSVVVFTLNHTT
                     GLNVPQLIELAIQTPLKAFVLSVPGILFLQFFSDFLWVFGMHGSSILAPIRQAPLLQS
                     IQENMDAFSVGKEIPNIITEPFTNAFGLIGGGGCILPLVIAILWASKRQEQRSIAKFG
                     LTTCLFNITEPIMFGLPVVMNPIYMIPCAIIPSINLVIAYAATSLGIISKTVAAAPWI
                     TPPVIQSFIATGGDIRAAVLTVILIILDVFLFLPFVLAANKAKLAEGGY"
     gene            25553..25978
                     /locus_tag="LY912_000704"
     CDS             25553..25978
                     /locus_tag="LY912_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954421.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGADSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATVTFTKIGNYRLKDKDGNIYSL"
     gene            complement(26476..27177)
                     /locus_tag="LY912_000705"
     CDS             complement(26476..27177)
                     /locus_tag="LY912_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBM6954422.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDTFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(27193..27633)
                     /locus_tag="LY912_000706"
     CDS             complement(27193..27633)
                     /locus_tag="LY912_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HBM6954423.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVLAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFEKLPVETYVGEYL"
     gene            complement(27633..28208)
                     /locus_tag="LY912_000707"
     CDS             complement(27633..28208)
                     /locus_tag="LY912_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBM6954424.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(28619..29098)
                     /locus_tag="LY912_000708"
     CDS             complement(28619..29098)
                     /locus_tag="LY912_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HBM6954425.1"
                     /translation="MFLDSGVVLKETELERIEYTDFGLGAIETEGLNLFVYENNERYC
                     GKELVLLPYQTCPEHRHPPRDENEGKKETFRCRKGLVYLYVEGKETKKLSCIIPKGQE
                     RYYTAKKEIILHAGDQYTIEQNIKHWFQAGATGAVITEFSSSSDDPSDSFTNPAIYR"
     gene            complement(29136..29615)
                     /locus_tag="LY912_000709"
                     /pseudo
     CDS             complement(29136..29615)
                     /locus_tag="LY912_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(29787..30488)
                     /locus_tag="LY912_000710"
     CDS             complement(29787..30488)
                     /locus_tag="LY912_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6954426.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQEILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(30596..32038)
                     /locus_tag="LY912_000711"
     CDS             complement(30596..32038)
                     /locus_tag="LY912_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBM6954427.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCMDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            complement(32052..33917)
                     /locus_tag="LY912_000712"
     CDS             complement(32052..33917)
                     /locus_tag="LY912_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBM6954428.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(34038..34889)
                     /locus_tag="LY912_000713"
     CDS             complement(34038..34889)
                     /locus_tag="LY912_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBM6954429.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(35199..35912)
                     /locus_tag="LY912_000714"
     CDS             complement(35199..35912)
                     /locus_tag="LY912_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBM6954430.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(35980..36306)
                     /locus_tag="LY912_000715"
     CDS             complement(35980..36306)
                     /locus_tag="LY912_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBM6954431.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(36429..36656)
                     /locus_tag="LY912_000716"
     CDS             complement(36429..36656)
                     /locus_tag="LY912_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBM6954432.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(36978..38231)
                     /locus_tag="LY912_000717"
     CDS             complement(36978..38231)
                     /locus_tag="LY912_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBM6954433.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            38292..39032
                     /locus_tag="LY912_000718"
     CDS             38292..39032
                     /locus_tag="LY912_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6954434.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(39118..39876)
                     /locus_tag="LY912_000719"
     CDS             complement(39118..39876)
                     /locus_tag="LY912_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBM6954435.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(39873..40901)
                     /locus_tag="LY912_000720"
                     /pseudo
     CDS             complement(39873..40901)
                     /locus_tag="LY912_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(40921..44088)
                     /locus_tag="LY912_000721"
     CDS             complement(40921..44088)
                     /locus_tag="LY912_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954436.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSKYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(44312..45196)
                     /locus_tag="LY912_000722"
     CDS             complement(44312..45196)
                     /locus_tag="LY912_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBM6954437.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(45291..45728)
                     /locus_tag="LY912_000723"
     CDS             complement(45291..45728)
                     /locus_tag="LY912_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954438.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(45945..46856)
                     /locus_tag="LY912_000724"
     CDS             complement(45945..46856)
                     /locus_tag="LY912_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBM6954439.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(47313..47741)
                     /locus_tag="LY912_000725"
     CDS             complement(47313..47741)
                     /locus_tag="LY912_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954440.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(47769..48407)
                     /locus_tag="LY912_000726"
     CDS             complement(47769..48407)
                     /locus_tag="LY912_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954441.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(48411..50393)
                     /locus_tag="LY912_000727"
     CDS             complement(48411..50393)
                     /locus_tag="LY912_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBM6954442.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            50573..51238
                     /locus_tag="LY912_000728"
     CDS             50573..51238
                     /locus_tag="LY912_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6954443.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT        15299 a        10951 c         8807 g        17352 t
ORIGIN      
        1 ttcttactat gcattttgat tgtgaattta aaagaaagag gttatttatg gaagataaaa
       61 aattgaaaaa acaacttagc tcccgacata tcaccatgct agctttaggt ggagcgattg
      121 gtgcaggtct atttaaagga agtggcgaag cgattggaat cgccggccct tctgtattga
      181 tcgctttttt gattggcggc ataattttat atatcgtgat gaaaggtctg ggaaaaattg
      241 ttttaagtgg tggtgatacg caccacggat tatctggatt gattcgtcca tatctaggtg
      301 ctcatgctgc cgattttacc gattgggtct actggtccat gtggattatc aatatcattg
      361 ctgaagctgt tgcagctgct tcctttttac agttgtggtt cccccacatc ccagcttggg
      421 tatttgtttt tatgttggct gttttaacta ctatcatcaa tctttattcg gtacgattat
      481 tcgcagagac agaatattgg ctggcctttg ctaaaatcag tgtcattatc ctattgatca
      541 tttttgctgc ttatcttgtc ggtcagcaaa tgttgggtac tggtgttttc cctacccttc
      601 aacaattaac tgatcatggt ggttttactc cccacggtat gaagggaatc atcagttctt
      661 tgcttgtagt tatctattct tacggcggtt ctgagttgat tgctatcaca gtaagcgaag
      721 cagatgatcc taaacgtgcg attcctaaag caatcaaagg cgtcatggga agaatcattt
      781 ccttttacat tattccttta tttttgcttt tgattatttt tccttggaat actttagcag
      841 gcacgaacgt tagtcctttt gtgatggtat ttgaaaaaat gaatattcca tttgcggcag
      901 atatcgtcaa tttcgtgatt gttcttgctc tgttctcgtc tatcaattca ggtgtatatg
      961 cttcttcgag aattttgttc ttccgcttga aagatcggaa aggttcctct agaaaactag
     1021 ctgttttaaa caagcatcaa gtaccgcaac gtgctgtgct gttttgtacc agtgttcttt
     1081 atctaggtgt ggctctttct tattttgtcg gtgacaaatt atttggctat ctggcaggtt
     1141 ctctttccta tacagtatta ttgatctgga tcattatcag tgctgcgtcc tttgtactga
     1201 cactaaggaa aggaacgtta tgggacaaag gaatcagctt ttttgcatta gcagtcttat
     1261 ggttgatttt ccttggtatc ctattcacga actccattgg ggtaactgta ttgaccggtt
     1321 tgctttacct gttcatttat ttcagttatc aaaaaaagaa tgatgctttc gtcttgacga
     1381 atgaatgaaa ccaatagaga attttattct atttatattg aatatctgga gctattgaaa
     1441 aaaaggagct gcgacaaaaa ttgttgcagt tcttttttcc gaataaacgg tgttcaaaaa
     1501 ccatctgtgc agattaattg attgttctcc acgctcatga catgatagaa gaaaggaatg
     1561 aagaaaaagg agtttgtttt aaatgaaaaa gtattggaag tttttgttga tgattggtgt
     1621 ttcgacggta gtcatgtttg gtatgatgta tttgaatgtt tatgcgcttg atcatatctt
     1681 cttcagtcgc acacgtgtat tcatggcgtt gatgatgggt gcagtcatgg cagtcatcat
     1741 gttgttgttc atgtggaaaa tgtatgaaaa caaaaagata aatgctatga ttttagccgc
     1801 tagtcttctt gtttttgccg gttccttatt tatggtacga agccaaacaa ctgtcaacga
     1861 tacggcgtgg atgaaggcga tgatccctca tcactctatt gctatcttga caagtaaacg
     1921 agctgattta aaagatcctg aagtaaaaaa attagcggaa gaaatcattc aggcacaaga
     1981 agaagaaatc gacaaaatga aaaaaatgat caaagaaatg gaatgaccat tatccatcca
     2041 aataaaaaaa gaggatgttc cagaagtgat caacttcaag aaataagaag aagctacttc
     2101 tggaacaccg tgaatcagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
     2161 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc aaatgcaagc
     2221 ttttgaacac cgtttattcg taaaagggag tgtgacaaaa gtcttgtcac actccctttt
     2281 tacgttttta ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt
     2341 tctttgagat cccccaacct gtaaaggcac tgaccatcga aaacacaggt gaaagcaaac
     2401 tgaaaaacac gaatggcaag taagtgagtg taggaatgcc aaatgtactt gctacgaaac
     2461 ttccggcgat tccccaaggc actaagtagt tgattactgt tccaccatct tctagtgttc
     2521 tccctaatac agttggatca aatcctgctt tttcgtaagt ttctttaaat gcattaccag
     2581 gcaggataac agatagaaat tgttctccaa taaagatatt tactccgatg cttgtcatca
     2641 atgttgtaaa aatcaatttt ggggtgttcg tcatctttct tgatactcgt tccataacgg
     2701 ttgagatcaa cccaaattcg atcaacaaac cacctaatga caatgttaga ataatcaatg
     2761 acacagttgg catcatgctt tcgattcctc cacggctaag tagtgaatcg atttgttggt
     2821 ttccagtatt tgaaacaaat cccgattcga tgacccctgc caacttcgtt aaggaagttt
     2881 gtgggttttg aataaagatc attcctactg ctacagcaat attcaacaaa atcgtcaaaa
     2941 ttgccggtac ctttttccat gcacacaaga gcattaaaaa tagaggaatc agtgaccaga
     3001 tcgaaatagt aaagtttgct tctaaaatat cagtcacttc acgaatagat gaaagacttg
     3061 cggctttact tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggaa
     3121 cagttgacca catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg
     3181 ctaaatttgt tgattcggat aatggagaca tcttgtctcc aaaaacggca cctgaaacaa
     3241 tggctccaac aacaagggct ggatttagtc ctagtgttgt cccaataccg aaaaatgcaa
     3301 tcccaatcgt tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaaa
     3361 caacaaatac agaagggacg aaccactgga cactaatcaa tttaaatcca atgaccatga
     3421 gggttggaat aattcctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa
     3481 taaagattgg aatgatcccc ggtttgatgc cattgatgat cccttcgtgc agccaatctg
     3541 tcgggtattt ttttatcact gcgtacaaca tgaccattcc gatagctgcc aaaatcgtga
     3601 tattaggtga aacctttaat ccgacaacgc caatcgcaat gcctaaaaca atgaccatca
     3661 atacaagtgt tgcttctaaa aaacttggtg ttcctttttt ttccatgata atctctcctt
     3721 ttttagttgt tcttatgttc taaaaaagtt aagatatcgg attactccgc cacaattcat
     3781 ccgcgattcc tcctttataa aaataaaaag acctgctttc aactaaggac gaatgactcc
     3841 gcggtaccac cttaattaaa aacagatctg tttttcactt tcaaacgatt attcaaatgt
     3901 atggactttc catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt
     3961 ctgaacaaaa cacctaacca ctactgcgtg aaaagttgac ttgtatgaag tttaccttcc
     4021 ataagatcat ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta
     4081 taactttcgc gcacaacttt atctttttac tagaaagtag cgccctcttg tttttttctt
     4141 gctactattt cttgatgttc ttgtttgatt ttttctaata gcttgggttc tctcaataaa
     4201 tctagagctg tattggcaag taattccgct gcaatcgcaa tagaagcaag tcctttttca
     4261 cttttagcag cagctttgaa ttcttctgta tgtccggcaa tatatgtctc agagattgct
     4321 acagtaggct gtatcgttgg aataacttgg ctaacatttc ctacatcaga agaacctaga
     4381 cttgttcttt gttccgtttc tatttcttca tcaggaaccc ctgcttcttt tgcatgttgg
     4441 aagaataagt catcgaaaga aggcgttacg atgacatcat cgactgcatt ttggaacaat
     4501 ccaaactcaa aagtcgtacc cgtgcttaat gcagcacctc gtacgatatt ttccactttt
     4561 tcatatactt tgtctaatgt ttgtcgattt cctgcacgta aatagaaacg tccagcagcg
     4621 tagtctggta tgacattggc cgccacgcct ccatctgtaa tgattccatg gatattgaca
     4681 tcttttggca attgcaagcg tagagcgttg attccgttaa acacttggat caaggcttcc
     4741 aaagcattta ctcctttttc aggtgctgct gctgcatgag aagcgacacc gtaaaatttg
     4801 atatcgactg gatcatttgc taaagattct gtcgttttcc cataacgaaa agctggatgg
     4861 acacataatg ctgcatcgac atcctcaaaa aaaccttccc gaacgaagct tcccttagct
     4921 gatccatttt cgcctccttc ttcccccgga gtaccataca cacgaatttc tccgccaatc
     4981 tcatcaatga attgtttcac tatgctggct gctaatacgg agtaagtacc aaataaatta
     5041 tgtccgcatg catgaccaat acctggtaaa gcatcaaatt ctgccaaaaa ggcaattgtc
     5101 ggacctggtt tattggaaat ataacgtgca tcaaagcctg ttcggtgccc agctacttct
     5161 ttttctaccc agaacccttc tttttccaat tgtttgatta aagctgctga ggaataaaat
     5221 tcataattac ttacttcagg atggtcgtgg atagctagtg caagtgcttg atattctggt
     5281 aaacggtatt gaatcagatc cttcaattga tttgttgaga gtgtggttgt cataaaaatt
     5341 tcctcctatg ctagtcgttt tttcttattt tctcccgaat gtttcccacg caggtacgct
     5401 tgaacctttt gatgtttttt cgattacttt ggctgtttct tctgtttgat aggcatctac
     5461 tattttttga tacgttttat tgtcttcatc ttcttttctt gcaacgatga tattgacata
     5521 aggacgtgca tgctcatcga ctggttctaa gaagattgca tcagaagcgg gattaaatcc
     5581 agcatctaca gctacaccgc tattgatgac tgaaatatct acatctgaca aagcacgtgc
     5641 tgtttgggaa gcatctaact cagaaatgtc tagatttttt ttattctcgg taatatcaga
     5701 aacggtaggc gcttggcctt ttgccttgtc cactttgatc aatccagcag tttgcaataa
     5761 cagaagagct ctgccgccat tcgtgacatc attagggatt gcaacttttg ctccatcttt
     5821 gatatcagcc acatctttta acgtattgga ataaattccc aacggtgcat taaccgtatt
     5881 cccaatcgat actaaatcag ttccgtgttc ttcattgtaa ttgtctaaaa agaattgatg
     5941 ttggaaggaa ttcaaatcga tcgatccatc tgctaaagcc gcatttggct gattgtaatc
     6001 tgtaaatttc acatattcca aatggatgtt ttcctttttc aaacggtctt tcacatcgtc
     6061 ccatacatct gtatcttccc caatgatccc tagttttacg gtcgtttctt ttttttcagt
     6121 tgtagctgct tttccttggc tgcatcctgc caaccaaata attgctacaa atgtaatgac
     6181 tgcaaaacga ataatttttt tcattttttc tcctccattt tcaatgtgtg acttttttaa
     6241 tcagttgatt actgataaat tgactcaaaa aaactaagac cagaatcaat aatgtagcga
     6301 caatcgttac atctgtttgg aatcgattat atcctctcga tatagcaaga ttccctaatc
     6361 ctccggcacc tactgctcca gccatggtag tcagtccgat cacattgatg atcgtcaacg
     6421 ctgagacccg aatgatacca ggtaaccctt ctaacaaata aacacgtaaa atgatgccga
     6481 ttgggctcgt gcccatcgct tctgctgctt cgatcacccc aggatcaact tctagcagtg
     6541 cattctcgat ttgacgggca aaaaacggga caacgccaaa aatcaaaggg actaaagctg
     6601 ctttggcacc aatcgtcgtt ccaactaaga aacgagtagt caaagctaaa agagaaagca
     6661 agataatgaa agggatggaa cgaatgatat tgatcaactt atcaagtatt tcgaacagca
     6721 gcctgttagc tagtaatcca tttggacgtg tcactactaa cgtcacacct aagatgattc
     6781 cgatgatccc accaatgaat gccgtccaaa aagacatata tagtgtttgc tttgtcgctt
     6841 cgatgaattc atccggaatc aaatagacat tcggcaaata tgttttaaaa aattcagtca
     6901 ttttagtttc ctccttcgat gactttgata cggttatcta attcattttt ttgtaaaata
     6961 gttactttta caccagattt aatcaaataa tccaatgctt tttgccgctg tttggtttct
     7021 ccagctaaag taacgatcaa acttcctaag ggtgtttctt gtaatagctc tacattaccg
     7081 tataagatat tcgctgttac ttggtacttg ctgtaaagat gagcgattag aggttcgttc
     7141 gtctggttgc cgatataact taattccacc aaccatttat ttgcaatctg atcggcaaaa
     7201 gcagcatggg cactgattgt ttccaatgct tggtcaaggt gtgtcgctgt ccgaataaaa
     7261 tctttagtca attcttcttc aggatgactg aaaatctgga tgctgctacc tttttcaatg
     7321 attttccccg cttccataac cgctaccttg ttgcagattt ctttgacaac ttgcatctca
     7381 tgagtgatca ggacgattgt tagacctagc tgacgattta gtttttttaa cagtgcaagg
     7441 atctgaaggg tcgttttcgg atcaagtgca ctagttgctt catcgcataa caacacttta
     7501 ggttcatttg ccagagctcg tgcgattgcc actcgttgtt tttgcccccc cgacagttgt
     7561 ttaggatacg cagatgcttt ttcttccaga ccgacaagtt ccagtagttc attcactttt
     7621 tgacgacgtt cctgttttga ttttccagaa tactttagag aaaaatctac gttgtcaaaa
     7681 atcgttcgac tttccattag attgaaatgc tgaaagatca taccgatggc ctttctttct
     7741 tttcgcaatt cttttggaga gagctggctt aaattcgtct gattgacgat gacttctcct
     7801 gctgttggtt tctgcaacaa attcatcacg cggactaacg tactctttcc tgcacctgag
     7861 taaccgacga tcccataaac atcccctttt tcaatcgtta aatctacaga atctactgcc
     7921 tgtatctctt tttctttttg tttgaaacat acagaaatat ctcgcaattc aatcattaac
     7981 attcctcctt gtctataaaa aaagcatcct caagaaaatg aaaatagtca ttttcttgag
     8041 gacgcctttt tgcgtgttac cacctcatgt tcaagctgtg ttcacacaca actcctcttc
     8101 aagtaccatc atactctagc aagatatcgg tcgcagccgt caccgcctta catctatgct
     8161 cgggatgaat tgctcgatgg ccattttcca atagtcgttc cttgcttctt ctcagctacc
     8221 gaagctctct gtcaaaggtt cttctatcgt acttaccatt tcaatgcaaa taatattcaa
     8281 aaaaaaaatc cttttactaa cataaactat gtcagtaaaa ggacgacgta tcgtggtacc
     8341 accttttttc ggaagtttcc ttccctcaag cccaacatct caaaaagaga gattggcgtt
     8401 cgttttaacg gtcgaacatt tccgaatttg cctacttatc gacaaattat tctccaaggc
     8461 cattttcagc ttttcttact tgactcttca caccagccag agcctctctg caaagtttcc
     8521 aagcttactt tccttctcaa cgaaatcaat attttgttgt tgggaataat ctacaggagg
     8581 aaaactgaaa agtcaagcat gaaatccaaa ttattttttc tatatttatt tttctgtttt
     8641 tttatctaac atttcaataa cagttcgaag atcttttcct tccgcaagaa ggttcaattt
     8701 ttccttctct tcgacgctat aatttcgaac aaaactggaa tcgggaatca aaacaacgcc
     8761 tagtcctgca cgtgaagcgg ctgtcgctcc tactaaagaa tcttccactg caaaagctga
     8821 aagagcttct aatcctgttc gttccaaagc tgtcagataa gggactggtg aaggcttgtt
     8881 ctccgatact tcatctccga acgtaaacgt atcaaagtaa tcggctaatt gaaagtgatc
     8941 caagatatct gttgctcttt tcgtaacagt tgtcgtagca atccctagtt tcatatgacg
     9001 ttcttttaag tctgtcaata tttcttttgc atagggtttc aattggatag ctccacttgt
     9061 cagctgttga taaaaatatt cttcacgctt tgctcggact tcctgcactt tttcaggact
     9121 gcctgctgcc tgcactaaaa tatcaaaact ttgtttccag ttttttccgc cccaagcgtc
     9181 aacgatttct ttcgggatat gaatatcaaa ttgctggaat ccccaaagcc aaccatcccg
     9241 atacgttctt tccgtatcca ctaacaaacc atctaaatca aatattgcac ctttcatcta
     9301 tattccaaaa caatacacct agtttagcat gactgatcca aaatgaacag aagcatagag
     9361 cccagccgca tcacttataa gagttcttgg aatcgacgga tatagatttt cttcacagct
     9421 gtcacaagcg ccagataagc gacgactgtt ataaacaacc ataaccagta attgccaggg
     9481 agcggcatca agcctaactc agcaccaaat cctgtgaatg gaaggactga accgacaatg
     9541 attcctaatg tagtgataac cagcatggca aatgttgcat tgctttggat aaatggtatt
     9601 ttcggtgtac gcaatgcatg gagtactaat gtttgtgtcc acagggattc gacaaaccat
     9661 cctgcatgga ataatgcgat aaaaatcact tgttgtgagc tatccaatgt atggaaactt
     9721 ccaccaacta cagcaggaca aataacaaaa tacatcaaca agtaagtagt gatatcaaaa
     9781 atcgaacttg ttggaccaaa ataaaccatg aattttccaa tactagatgc attccatttc
     9841 tttggctcat ccaaatattc tttatccatc cgatcccatg gtaaggaaat gcaagaaacg
     9901 tcatagatca gattcaaaaa tagaagttgc aaaggcaaca ttggtaaaaa tggtaagaac
     9961 gtactggcaa tcagtacgga aaacatattg ccaaaattag aacttgctgt tgccttgata
    10021 tatttcatga tgtttccaaa agtttctctt ccagaaagaa ggcctctttc caaaatcgtc
    10081 aaatcttttt ctaaaaggat cacgtctgct gattcttttg cgatatccac agctgtatcc
    10141 acggaaatac cgatatcagc cactttcatt gctggagcat cattgatacc atctcctaaa
    10201 aatccgacag tatgcccatt tttacgtaaa gctgtcgtca atcgtgcttt ttgctgagga
    10261 ttcaatttta cgaatacttc gtgttcttca gctacttgcg ctaattcatg atcattcatt
    10321 tccgagattt tctcaccagt aatcaattca ttgatttcta ggcctacttg acggcacaca
    10381 gaccgtgtga ctaattcatt gtccccagtc agaactttta cagctacacc atgttctttt
    10441 aaagctttca acgcttgttt tgttgtttct tttggtggat caaggaaagc aagataacca
    10501 atcagaacca tgtctgactc atctttgact gaaaattctc caacaacgct tggattggtc
    10561 ttttgtgcga caccaatcac tcgtaagccg tcttcattaa gtgattgtac ttttgcaagc
    10621 accgcttctt ttcgttcttt tgttaatggt gcgacagtac caccaagatc aataaattta
    10681 gaaatgttca acatttcttc aatcgcgcct tttgtgatca tctgtgtttt gccagccgga
    10741 tcagcgacta caacactcat acggcgacgt tcaaaatcaa aaggaatttc atctactttt
    10801 tgataattga ttgtatctgt atctaaagtt tctgctgctt catcaatgat agccacatct
    10861 aacaaatttt tcagccctgt ttgatagtag ctgtttagat aagcatggcg caaaacacga
    10921 tcatcttcat ttccttcaca atccatatga tattcaagaa tgattttgtc ttgtgtcaat
    10981 gttcccgttt tatccgtaca taacacatcg atcgcaccaa aattctggat agcatttaaa
    11041 tttttgatga ctgttccttt tttggccatc acacttgctc ctttgaccaa attcgtcgta
    11101 acgatcattg gaagcatttc aggcgttaaa ccaactgcca cagataatcc aaaaagaaaa
    11161 gcttctaacc aatctccttt tgtaagccca ttgataacga taactgctgg agccatcaat
    11221 gacataaatt tgatcagcag catggatgtt ttgtggatgc ctaattcaaa acttgattgg
    11281 atgggttttt cagatagcgt ttctgctaca tgcccaaata gtgtgtcatt tccgacagaa
    11341 acaatgattc cttccgcgct tccactgatg acattgcttc ccataaagac aagattttca
    11401 taacttgttt cactttgctg atcgtcttca catactttcg catgcttttc tactggatag
    11461 ctttcccctg tcaatgctgc ttgagaaatg aatagatcct ttgcggacaa taaacgcata
    11521 tccgctggta tcatatctcc tgctgaaagc cgaacaagat ctccacagac gatttcttcc
    11581 ataggaatct ctgtatactc gccatttcgt ttgacagctg ccgttacttt cacaagtgat
    11641 ttcagttttt cagctgcttg attagaacgc acagactgga tcaacgtcat cgtcccactg
    11701 acgataacca tagtgaagat aatggctaca ccaaagagat ctttatctcc tggagcggct
    11761 aatacgtatt ccgtaatgaa tgaaataatt cctaatgcaa tcaacactaa tgtaaagggt
    11821 gtgatgtatg ctttcaatat ttctataatg aatggtgttt ttttgccata tgaaatcgca
    11881 ttttcaccat aagtttctct tgaacgctcg atttgttctt ctgacaatcc atttggtgat
    11941 gcatggaaca attcaaataa ttcttgcttc gtttttccag caaaagctgc atagattttt
    12001 tgtgtatctt tctttttttc catctcgatc tctcctttgt gtccaaaaga cagctgttct
    12061 cgctgttttt ggtcttttgc tattcatcgg atcgatagag aaaatgctga aaggggctga
    12121 gaacagatag ataatagccc tggcctttcc tctaaatcct tgtttttcga atgactgtca
    12181 tccatttgtt ctcatctcct ttactaagta attttaattc atgacttcca atcatttttc
    12241 gaatagttat tttcccaact cgctcacctc cctttttgtt ttttcaccta tgggatttgc
    12301 ggcaacaaaa aaacctctcg ccaaatactc agcgaaaggt ttgaaaaagc aaatcaaaaa
    12361 aagcttctca gatctcatcg ttgagttttg acactgtaca acgtaaaaag cagatatctg
    12421 cttttagcta ccttatgaaa agccttatct cgacaattcc tgttctaccc attggcgtct
    12481 ctcgacgttt ttgggcagta gcctatgttt gtataggagc ctcacctaac aaatcctatt
    12541 cggttttccc tcgttaatat aacaactaaa aaagaggatg tcaaatcaat tttccatgtt
    12601 tttcatactt ttttaaaata cacgcgttat atttcctgtc tcacgcagtt ttatttgtct
    12661 cattttccac ctcccgctat aatagaatta tagtaggaaa cgaggtgctg ttatggaacg
    12721 aacacttgtt attatcaagc cagacggcgt aagacgccat ttggtcggaa gcatcatcca
    12781 acgttttgaa gcaaagggac tggccattgc tgaaatgaaa tttgcaacga tgacacctga
    12841 actagcaaaa gaacattatc agcacttgac tgaacgtagt ttttttgatg agcttatcga
    12901 ttacatgact tctggtccgg tcgtttatct tgtgctggtc ggcgaggaag tgatcgatat
    12961 cgtccgtaag atggtcggag caacaaaagg ggcggatgcc gttccaggta cgatccgagg
    13021 agattatgca ctgccgggga ctgaaaacat catccatgct tctgattccc gtgatgctgc
    13081 aacaaaagag atcgcccgct ttttcccgcc attcgataca aacaaaccgt ctgaaaaagc
    13141 ggcgaagtga tacaaatcct aaactgttgg tctaactgct gggtttagca atggccagca
    13201 gttttttctc taaagaattc ctttgattct tccctaatgt atattcgatc actgcgaaaa
    13261 actcttggtg attttccgat ttttcttccc ctaaagcagc agaaatcagt cgttggtaat
    13321 aatccgccat caatgtttca taaatcactg tacttctttc tttatgcgct aaactccgtt
    13381 tcatatcttc attcacgcta cgtgcctttt ttaagcgacc attttctata taaaacaaag
    13441 tcaagttcgt caaaaaagta aagagatact gctcgtgatt attcagttgc gcgatccgtc
    13501 gcattctttt tttgattttc aaataattat tctcaataaa acgatcactg aatatccaag
    13561 gaaaatctgc tagaatagat acttcaaatt gcccatactc tggtacttgc atcaaatatt
    13621 cttcaatgat acgacattca taacgcaaaa attcaaattc cgtctcagat acttctgttt
    13681 ttttggacat gtgcagattc aaaaccaaat agtacagatc ttctgttttc ttatagtgcc
    13741 tgcggttatt agcaatttct ttgtaaggat caaagctgtc ttcttgaatc cgatctagca
    13801 ttcgtctttt tttctttaat ttttttggct catcaagctg atttcgtatc cattcatatt
    13861 cggcaagtgt catgttcatt cgctctaaaa atgatttcaa tgttccaaac gatacttttt
    13921 tcactgaatt tgtctcgatc ccgactagcg aagttttaga acagattcct tccgctaatt
    13981 gggtctgtgt cagctttttg ttgactcgaa gcttcttaat caattctcca tcatacataa
    14041 tagttctcct tttttaattg aaattaaccc ttggcttttc cagaatgctt gccaataaga
    14101 ggaatgatta tttcaattta aattttccgc attcaataaa tagatacgtt aaaaataaaa
    14161 aatacacgaa aaaaataaaa aaatgttttt ctcataaaaa ataccaacct tcaagcatga
    14221 gactgctgtc taatccctga aggttggttt gattgtttat tgatcatttt tttactgctc
    14281 cgcattggtt cctgttactg gatataggat agtcgttgtt ttattgccgt tttttgaaaa
    14341 gacactggtc gaatgttcac ctttttgctt ttcgattgct tcattacgtt ccgcttcgtt
    14401 tttatagtca tattttttcg gatcaatcgt ctcaaatccg tttggcacat aaaaccgcaa
    14461 gagattttcc tgattcagct tatctgaaag acttaacgca gtcttgactt tttcctgatc
    14521 tttggagatt tcctcgtcga ttcctgctgc tttcgtatcg atgatttctc ctgtctgatt
    14581 attgtaagct tttcctccta ggacggtgta tttgggcgtc acgaagttcc catttcgaaa
    14641 agcaactact tgatcgtgct gagaagataa taagtctgta ccaaaatgaa gataatcttt
    14701 atcatcgatt cccaatagat gtagtaatgt cggcaaaaca tcgatttctc caccatattc
    14761 atgattgact gtccctttag tgtaaccagg catatggatc atcaatggca ctcgttgcat
    14821 ctgtgcgttg tcaaattcat cccatgtatc tggatcttta ccaagagcac ttgctaaatc
    14881 tttattatct gtattcgaga tcccaaaatg atccccgtaa atcacaaaga ttgaattttg
    14941 gtaaatacca gattttttca aatacgtaaa aaattgttcc aatgattgat ccagataatg
    15001 ggccgttcga acataattat ctactgtgct attgccagta ttcaaagatg gaaagtcgaa
    15061 attcttgtca tccgtataat aaggcgtgtg gttggttacg gaaagaaatt tcgtgtaaaa
    15121 cggctgttgt agatgttcaa gatattgggc agattctctg aataaatctt tatctaatat
    15181 cccataacct aacgtttcat cggattcatc aaaataagat cgatcaaaga aattgtcata
    15241 ccctaaattt ttatatacat gatctctatt ccagaaacta gctacattcc catggaaaac
    15301 agcacttgta tagccttctg tttgaccaag ggtcgctggt gctgcttgaa agacattatc
    15361 tgacccaagt tctgtgaata atgagccttg aggtaaacca aatgtgccag tttccaacat
    15421 gttttcagca tcacttgtct ttccctgtcc tacttcatga aagaaattgt caaaactgat
    15481 cgttgcttga ttctggaaaa tactatttaa aaacggcgtg acttcttgtc cgtctacctt
    15541 catattgatc aaaaactgtt gaaaactttc taaatgaagg acaatcacat tttttccttt
    15601 agcaatccca aatgtttcag gatttggctc tgcataatgt ttctttgtat agtctaaaac
    15661 ttcatcaatt ccattactgc ttgcatgcgc gcgaacactg ctagtcattc ctgttttgat
    15721 tccgtcataa atagtgtacg catcgattcc tagatatttg acaatatagg aacggtcaaa
    15781 tgtccgctgt agcaattggg gacggttggc ttcgctcaac gctaaatttc ctgaaaaaat
    15841 caatcctgaa agacaggtaa cagcgatagc catcggtttg ctgacagggt tgcttttgat
    15901 aggtattttc ttgaccttca accaaaccag tagcccaatg aacacagcga tatccaacca
    15961 atagatgaca tcatggggtt tcatcaaaga aaaggagctt cctgacaacc cttgtgacac
    16021 tttcgaaaag cctaatacag atttgactgt aatgaaatct gtgaattccc gataaaaaat
    16081 aatattcaag tacaacaaaa gcgtatttaa aatatcaatg atcaaaagaa tggctaacgc
    16141 tggctttggc tttttaatat acaaagaaag gccaaaaaac aataaggtag tcgcaatcgg
    16201 gttgatccac aagataaagt actggatcgt accttccaca cctaatgaaa aatctgcata
    16261 gtaggcaatg atcgtcttca gccagaaaaa gaaaacagct gtcaaaacga ttgctaaacg
    16321 attttggcac aattttttaa gttgtgtcac gtatatcact tctctctatt cacatttttt
    16381 cttattttgc tcctgaaaaa tgaaaatttc ctaaaaaagt tgttatctta agattttttt
    16441 attctttcta aagattattc cattcatttt tcacagcata aaatcgtttc ggtgtaagcg
    16501 gttaaaatag taaggagata aaaatcttgt ggtgaccgat ttactctata gtattcaaaa
    16561 gtagtttctc ggtattcgta caaaaaaaac atactaagat tagaggggaa catcattgac
    16621 gaatgatgtt ctcctctatt ttctattttt agattatagt gaagagtgaa agaaagttcg
    16681 aacaaagcct tgaggactac gagtccctat caaaaaccga acttctttac tgtcatttta
    16741 gaatcaggtt tacgtatgtt ggggccatga gcccgtgtat aggaaattgg aatcgaaatg
    16801 aagcagtaaa gttctttcaa cacttaaaaa ggaggaaaac aaatgcctta cattcttgca
    16861 ttagatgttt caatgggaca cagctacagt gtcctataca aagacgacac ctgcttattt
    16921 gaagacgaga tcgaacacac tcaaagagga tttcatgcat tactcgaaga gatccagcac
    16981 ttgcctgaac gtccattgat tgtttttgaa gcaacgggta tttattccag accagtcgaa
    17041 aagttctttc aagatcatca cttttcttac tgtttgttaa acccgttaga agcgaaaaaa
    17101 cagatggaag aaaacacctt acgcagttgg aaaacagata aatcggatgc ccatcggctc
    17161 gcacagactc atcttaaaaa tcaacgtcaa ccaaaagaag tacaaagcaa tttttactta
    17221 gagatgcgcg atttagcccg tttttatcaa gaaattgaga agaaaatcac tcgactgcgc
    17281 atggatttac acaactgcct tcagttgact tttccagagc ttgaacagtt cttttcaaac
    17341 aggctgaccc cttacgcatt gacattgatc cgtctttttc cccatccaga ttttgtattg
    17401 gcatctactc ggacaaaaat aaaaaataaa ctgatcaacg aaacacggga aaaaatctcc
    17461 gcgaatcgtg ccgagcaaaa ggcagatcaa atcatccact atgcacagtg tgcctatcca
    17521 gctgttgaaa aagacagtat tcactgtcaa aaaacgatct attacgccga acttctccaa
    17581 gatttactcg aacaaaaaaa agcactggcg acacaaatga tcaaaaaagc cgaagcctct
    17641 ccttgctttt tgttgtacca aacgttccct gggattggcg cactcacagc cgctttattg
    17701 ctcggtgaat taggagatat cacacgattt aaaacccata aacaattgaa tgcctttgtc
    17761 ggaatcgaca tccgacggta tcattcaggt aagtatactg gccaagaccg catcaataag
    17821 cgtggtaatc ccaaagcacg gaaaattatt ttcttcacca ttcgaaatat gattcgccag
    17881 caacgcgcag ctcctaatca tattgtcgat tattactaca aattaaaaaa gcaacctatc
    17941 cctaagaaag ataaggttgc cacagttgct tgtatgaaca agcttctgaa atgtatgcac
    18001 gctatggtta gggcacatac agagtacgac tatgcgtacg cggtctcagt ggaccattaa
    18061 ctaaaccact tacagtatac cacttctttg cccagatcga aaatttttta cgaacggggc
    18121 tttatttagt gtgccttgat tttgtcgctt tcgtttacga gctatttttc ttgcaccttt
    18181 tacttgacta atcgtaggaa agaggctgtg acaaaattct tgtcgcagct ccctatttct
    18241 tgatgcagga cagctttttc acaacctctc cactaaacgg tgttcaatca gctgaccttc
    18301 ggtattagct caaaaaacgg caaaatatga ggagctattt tcccgttttt ttctctaata
    18361 ctcaggtcaa accgctgatt tcacaacctc tgattcacgg tgttccagaa gtagcttctt
    18421 cggaaataag ccgaaatttt acaaaaactt gagaagcact tttcgtaaat ttcttcttat
    18481 ttcttgaagc tgaccacttc tgtcacaact tctgtttttc attgtccata ggtttgatat
    18541 tgtccttctg atgactcatt cgtaatgatt gaggcttgat tttcttcatt tcccgttatc
    18601 gtttgtccac tgccagaatc tgaagggctt agttctgtcg actcgttttt ttgagaagaa
    18661 gcagttgttt tcttgacttg ttcgttggtc tttttccatt ccgctagtcg atcggccacc
    18721 acttttttgt ccactttttc agaataagct gtaaccactt ttccattttt caaacgtgct
    18781 accttgtcgc catcatgagt caaaagcaaa acgaccaaat gtttgtcttt gaattgatat
    18841 tgtctgagag aaatcgcact aagtacgtca tcgatattga taaattgatt ttcttctttt
    18901 ccttttggca aatagatgtc caattcacct ttttcgtaat tggcagttaa tttatattcc
    18961 tcccaccaat aagttgagaa ttcttttttg aaattatcta ctgattcttt gcttgctacg
    19021 attttttctg tttctttctg agcaagatct gctgtcattt ttcctgaaaa tgctgcggat
    19081 aaaataagca gtaagaaaaa accgaataac caaaagagaa gaaacggtct ttttttcctc
    19141 atgccttcct ccactcctat ttaattttga ctattctatt atatacaaaa aatgaaatag
    19201 aaagacaaaa aagttgaaaa agatcgtaaa taattgaact tctttttcct gaagcggtaa
    19261 gaacgggaat tttcatacat tctctcttgg ctattcttta agcttcaaat ccatttctgt
    19321 ctgatacatc tttgaaccaa tgacccgatt tcttgatcgt tctttttcca tcttgtgcta
    19381 aatctactga aataaaaccg taacgattct tataggcatt ggtccacgac cagttatcca
    19441 tgcatgtcca catatgataa cctaaacaat tggcaccttc ttgaatggct tgatggacat
    19501 atttcagatg agattgaaca aattcgatcc gataatcatc gtggatcata ccatcttcct
    19561 tgataaatcg tgcttcattt tctacaccca tgccgttttc agaaataaaa cagtcgatat
    19621 tcccataatg atctcgtaca ttgatcaaaa tatcatagat tcctttttca tagatctccc
    19681 atccgcgata aggattcatt ttacgaccag gcatttcata attgtcgaag taatcctcag
    19741 gcataggacc gtttttagta tcgattggtg tttcttttgc ttttattcgg cgtggttggt
    19801 aataattaat tcccaaaaga tctactgtgt tttctttaat gatcgtcaaa tcatctggat
    19861 gaatctccgg cattagatcg agttctttta ttctctcaat caattcactg ggaaactcgc
    19921 cttttacagc tggatcaagg aatgaacgat tgaagaacgc atctgctatt cgtgctgctt
    19981 taacatcttc gggatttgat tcgtctcttg gataactcgg tgtcaaattt aagatgattc
    20041 cgatcacacc gctttgatcc atttcatggt aagctttgat ggctaatgct gaagccaacg
    20101 cttcatgata accaacttgg attgcctttt tcatatctga ttcttccgga taatgccatc
    20161 gatacaaata gcctgcctcg actggaacga ttggttcatt atgggtaaac cattttttta
    20221 ctttcgagcc aaacaattga aaacaacttt ttgcgtattt ttcataggct tcaaccgttt
    20281 ctcggttcaa ccatccgcct ttttcttgca gatacatcgg catatcgaaa tgatacagat
    20341 taacaaaggg ttcgataccg ttttcaatca actcatcaaa atagtgatga tagaaacgaa
    20401 cggcttcttc gttgattgtt ccagattcat caggtatcaa acggctccat tggatagagg
    20461 ttcgaaatga attatgccca gtctgtttca tcaactgtac atcctcttga tacttcgtat
    20521 aaacttgcga ggttttttca ggtcctactt gatcaaagaa cttttgcggt tcgtttttgt
    20581 accaataatc aaaaatattc tctccttttc catcgcctga aattcttcct tctgtttgtg
    20641 gaccacttgc tgcagagccc caccaaaaat tttttggaaa ttgatatctt ttcatcaaag
    20701 cacctctttt tcttttttag ttgattccat gtatgatatt ttccatcaca atcacttttt
    20761 cattttcttc ctcttctttt ttgattcgtt tcaacagctg ttctgctgct cgttccccga
    20821 ttttatctgt tggtggcgtg atcgtgattt ttggaaggat actcagatcg tttttatcta
    20881 aataatcata gtgactgaac gcaatatcct tcccgattct gacaccttct tgattgaaac
    20941 attcgatggc accaatcgac atgttgtaat tgctgacaaa aatagcagtt gccccttttt
    21001 ctaataatgc ttttgccccg taatagccgc tttttctaga atagtctcct gtaaagatct
    21061 ctaaatggat agacggatcc ttttgtaccg cttctttggc tccagctaaa cgttctcttg
    21121 ctacgtaatc tgtttgagcg gcagcaataa atcctattgt tttatgtcct tgtccgccat
    21181 gatgagcaat cacttttgct acactttctc gatcattcac tactattgta tcaatacctg
    21241 ctggcccacc cggacaattc aatgcgacaa ctgggatact catttttgtc agcatttcaa
    21301 atccagacca ctcttcttct gataagaaga cgatcaatcc atcgatcgca tgcttcatca
    21361 ggtattcgat tttttgttcg attttttctg gctgatcggc aaacccgctt aataataagc
    21421 tatacccatt ttcttcagct actctttcga tccctgaaac aacctccgaa ccaaatcggt
    21481 tagatatccc gtttatcaac agtccaatag agaaacttcg attattcttc aatcctttag
    21541 caatgatgtt ttctttatag tccaacgctg aaatcgcttc tgatattttt tccatattct
    21601 tttccttcag ctgctgaccg tttaaatagc gggaaactgt tcccactgaa acaccagcca
    21661 tcttagccac gtcacggatc gatgccatac attttcactc ctgccagtta catttgattt
    21721 ctttttcttg ttgttcgacc atgatgaccg ctttctttgc ataatgccgc ttgtcatcaa
    21781 tatccatata actaaagtct tcagaagtga gttcaaaaac aagcagtctt tcctcttgag
    21841 accgcaattc atctttacga aaagctttca ataatttcgt tctttggatg acaacgccgt
    21901 caattaatcg gacatagaca agagtacttg ttttacctga aacacttcct gtatttttaa
    21961 ctttaattga tattattact ttgtcaatat ccgttttgac ttccatctga ctgtattcaa
    22021 atgttgtata gcttagacca tgtccaaaag gataaaatgg acttccgctt aaatcataat
    22081 aattctcttg tttagaagca gcacgctgat agtaataaac aggtagttgc cgactatttc
    22141 taggataaga caaactcaat cgtccgcttg ggttatttct tccagaaatc atctgcgcaa
    22201 tggcttttcc accctcctgt ccaggaaacc atgctgttgc aatggcattc gtaaatgact
    22261 cgattttcat caaatcgtag ggtcttcctt gcacaagtat cgtgatgatt ggcttgccta
    22321 gttgatacaa ttgttcaatc agctgttctt ggtatccacc taaagaaaga gaagcaacat
    22381 ctacattttc tccagaatcc atgttgatcc ctttcgatga aactgccccg ttacgaagaa
    22441 attccatatc aaagttccgc gcacttgatc cacctagaac tgcaatgatc acatctgagt
    22501 tttgagcaag ggtcaccgct tctaataatt tttcttcctg atcctcctga tttcttactt
    22561 cacatccttg tgcataagaa acctttgatt ggggaaactc tgtttttatc tcttgtacta
    22621 tctttttttt caaacggtct tctgtttgtg gtgcagagta gtctcccaac aagtggtaaa
    22681 catcgtgagc atttggacct ataacagcaa tgttttttac ttgttgatcc aacggcaata
    22741 taccgtcatt ttttagtaaa gtgatacttt cttttgctgt ctctaaattt aagtgctctg
    22801 attcctccat gagatgatcc caatactcct ttggatcgtt tgcaaatggc tgttcaaata
    22861 aacctaataa aaatttgaca gataaaactc ggcgaactgc ttgatctagt agcttttcat
    22921 ctacgacttg attatcaatg gcttctgcaa tcttggtata ggtctcatcc cacaaactga
    22981 gatcgattcc tgccgctaat gcatatgctg cagcagtctt tttatctgta aaaacatcgg
    23041 ataaacgatc caaagccaca ccgtctgcca taacgattcc ttgataaccg atctcttttc
    23101 ttaatgtttg ctcaaaaagc gctcgattga tatgacaagg tatcccgtcg atgtcattat
    23161 aagcagccat gacacctact gcatttcttg tactcttcaa taatggtccg taaatatcgg
    23221 agaactctct gcgtccaatc gttactgtgc ctgaattatg accgcctaaa gcttctcctt
    23281 gtgcgataca gtgctttaac acaacaccga tctgatcctt cttcttattg atttcctcta
    23341 ctgtctgatc aagaaaagaa actttttctg aaataatctc tccttggaac cctcgaacga
    23401 ccgcttcaga aaaacgagct gagagaatcg gatcttcccc aaagcactct tctgtccttc
    23461 cccaacgagg atcttttgcc agatccaaag tcgacaccag cgctaaatga acacctttag
    23521 cagccagttc ttttgccatc aatcgactcg attgttctaa taatgctaca ttgaaagtat
    23581 ttccacggcc gatattcgtt ggataagaaa tcccatccaa gccttgatga ccatgtggac
    23641 attcttctac aagcaaaact ggaattttcc atcgcgaatg ctgtagtaca tattcttgga
    23701 ctaggttagc caccttccag ctttcttttg caggaatccc attcttataa tctgttttag
    23761 accacggatc agagcgaaac agaccgtata aggcacccag accgcctccc catttaacat
    23821 gttcttttaa cttttctgtt aattcgatct tgtctccgtt tttttcataa cattcccaac
    23881 catacaaatg ctggtttacc tgtcctactt tttcagcaat attcatcctc gaaagtaaat
    23941 cttctactct ttggcggatg gttaactttg ggttttgata cgggtaatcg tacaccttaa
    24001 tatcctcctt ctgccaattt tgccttatta gcggctaata caaatggcag gaataaaaat
    24061 acatctagaa tgataagtat tactgttaag actgctgctc gtatatcgcc tcctgtagca
    24121 ataaaagatt gtataaccgg tggagtgatc caaggtgcag cagcaactgt tttactgatg
    24181 attccaagac ttgtggctgc gtaggcaata accaagttaa tagatggtat aatagcgcat
    24241 ggaatcatat atattggatt catgactact ggtaatccaa acataattgg ttccgtaata
    24301 ttaaataaac aagtagtcag accaaattta gcgattgatc gctgttcttg acgtttagaa
    24361 gcccacaaga tagcaataac taacggtaaa atacacccgc cacctccgat caatccaaat
    24421 gcattggtaa agggctccgt aataatatta ggaatttctt ttcctactga aaaagcatcc
    24481 atgttttcct gaatagactg taacaaaggt gcttgccgta taggagccaa aatactcgaa
    24541 ccatgcatac caaacaccca taagaaatca gagaaaaact gtaaaaataa gatgcctggg
    24601 acggataaaa caaaagcttt caatggtgtc tgaatcgcta attcaattaa ttgcggaaca
    24661 ttcaaaccag tcgtatggtt taaagtaaaa acgacaactg aaaaaaataa aatgacaact
    24721 atttctggta ctaaagaatt aaatgacgca gctactgccg gtggaactcc ttctggcatc
    24781 ctgattttaa aactcttcat tttcgctaat ttgataaata attctgtact gacaagggca
    24841 gcaatcatcg ccgttgctaa gccagacgaa gaagtcagac tttgtaagaa aacccctgta
    24901 gcttctgctg tatttccgtc catcaaagtg actgtacttg ataaagacat caaaataaac
    24961 attacggctg tacttagaat tcctgcatga acaggactaa atgatggatc atcaatcacg
    25021 cctgtttgga tatagtgggt tgccaaattc cagccgatat tgtaacacac gataatagct
    25081 aaaatactca tcgtaccatt attcacgatt gaagcaagtt cagccaatgg acttagatca
    25141 agtattcttt ggactgttgc atttgaaaaa atcagagcat tcagcaaaac catgacagaa
    25201 gcagccatta ctaacggcat agtaacgata aaactgtctc gaatggccag caagtgtcgc
    25261 tggctactca tcttagatac gattggtagc attttttcag atagtctgtc tacgactttc
    25321 attatttcat ctcctagatt ctaaaattga accggttcat ttttaatata gcactttttt
    25381 taaagattgc aacacatttt tttaaaacgc tttctaaagg tggtggattt tttatgactt
    25441 ttgaaaaatt attctattta atggtatttt gtgaattttt tctcttccat ccgtttgaag
    25501 ttttactttc caatggtata atttctttat cctatcaaat gggggaagta ttttgaagaa
    25561 attaatcgta ctatttattt tgtctgcggg acttttgaca ttgactggct gtgatttgtt
    25621 tggcggctct gaccaatcct cggacgaaac aaccgattct tctgtcttaa aagcggaaaa
    25681 agcagatatc accaacagtg tatatacgct aaaagtacgt aaagatatgg atttatccgc
    25741 gggacagttg acatttacag ataaaaaaat ggaatggaca cgcacgtatc agacacaagg
    25801 agctgattct tctgaatcat ctgaagaaaa aacagtgctg acagatatca agattactac
    25861 caaagatgac gaatatatta tttcaggaaa agaaaataaa aaagaagcaa cagtcacatt
    25921 taccaaaatc ggtaattacc gtttgaagga taaggatggc aacatctaca gtctatagtg
    25981 ccatctgttg gatcttcttt tgtttctccc cttcttttct gctatagtaa agaagcaaga
    26041 tgactgtaaa ggagacgaaa tggatgatcg atagtcctga ttattgtaca tgtaataaca
    26101 acaaaaatat ccatacagaa tttaatgatc aaggaagttt gagtatatgc gacaattgcc
    26161 acaaactagt caaagattct tttaaatcgt ttgaatctta tcctgtcaaa aattatgtaa
    26221 aaagcaaaag aagataagca aaatcaagca aaactcacta tggctgattt ttatgaactt
    26281 caaactcagc ttcttccttt gatcaagctt caaaaactgg aatcagtaaa acaaacagtg
    26341 gatcatttca gttcacaaat caaagagtaa cgttttattt atttcacatc tttgaatata
    26401 aaataaccaa acgatagaaa gacttattct acatcacgta gtaatttttc tttcccgtcg
    26461 tttggttttt tacttttagc ctaattcttg acctttcgca tgctgattat ctgtaaaata
    26521 ttttccagca ggctttcctt ccaattcagc taatttttct tggatctgac gaatcacctt
    26581 ttttgcatct tctggatttt ctacaaaatc gaatgtatcc ccatccactt gtattttagg
    26641 acatacatca aaatcctcat accattgatt atagcgggtg ttcagtgttt cgtaataggt
    26701 gtataacgtt tcatcgcttt ctagctgttc atagtcacgc ccgcgttttt tgatacgttc
    26761 tagcatcgtg tccaaagaaa ctttgatatg gaccatcaaa tcaggacgtt tttttggagc
    26821 aacatcatct aactcgttta gcatcgtatc taataagcta tcgtactgct gtacttcgat
    26881 atccgttacc cgacctaaat cagcatttag atggaacaac agactatctt cgtagatgga
    26941 gcggtctagc acattgtcat cgttcactaa agcatttttc attgctaaaa atcgcttatt
    27001 caaaaagaag atttgcaata aaaatgcgta ctgctcagga tttgaataaa aaagcggcaa
    27061 tacttcgtta tcttcgacat tttcataaaa tggtttagaa tcaatctctt ttgcaagcat
    27121 atccgtcaaa ctgctcttac ctgcaccaat cgttcctgaa atcaaaatca ctgacataca
    27181 acccttcctc ttctataagt actcgcctac gtaagtttca acaggcaatt tttcaaaatc
    27241 atattcacgt acagcttggt ctgattttaa atacgtgtga agactttgtg taatcatcaa
    27301 gttcgtaggt accgtctctt cttgtacgat gatcatcggt tttttcaaca tagttgccac
    27361 acctaattcg taagccgttc ctggatcgat tgtttgatgc tcaaagtcaa ggatagccaa
    27421 aacaaattct gcatttgtca actcttccat atctttttcg tatacttcct gcgcccatcc
    27481 agcgctgaat agttcataat tgctttcttg gtgatgacgt ggagagtaga aacttgtgac
    27541 tgttttgttt tcctccaacg ctttttcgat acgacttact cgatcgattt gctcctctga
    27601 aaaaaatggt cctgctaaat atatttgact cattattttg cctccttcaa taataactga
    27661 tttttaatag atactgctcg taattcattg accagttcca atggattgtt ggaaaagatc
    27721 acttgatcca accatttttt atccataaaa tcctcttttg caaaagtttc taataattgt
    27781 tgcaagccgc tgtaataacc gccaatattc aatattccga ttggcttatc aggtgtcagg
    27841 ccgatcgcta tccaagaaag aagttgcgaa aattcctcca atgtacctag acctccaggg
    27901 aaaacgagga cagcatctcc tttttcaaat aataatacct ttctttcatc aattgtctct
    27961 gtaggaataa atgtagtaac atctttccca ggcagctcag tttcaaaaag gccatttgga
    28021 tagatacctg tgacttttcc gttattttcc agtactgttt tactaatcac tcccataatc
    28081 ccggagtatg aaccaccgta aaccagttcg atttcttctt gtgccatata ttttcctaac
    28141 gtttgcgcaa taaatttgta actttcttta ttgccaaaac gggaaccgca aaaaacagta
    28201 agtttcataa aaaaacactc cctaactcaa aagtctatct tcattctaca cgtgtttttt
    28261 taaaataaaa gactagattt tgtagttttt tagtggtata tagatcaaac accactatat
    28321 atagtatttg caaaaaaata atttttcagc tattttacag taaccaaaaa aataaataac
    28381 tagtaaatat aaaattgaaa cgacttactt atagaagaaa ttgggatttc gtcctgcatg
    28441 tcaataacac gcattattta aatagtcaca cacttgtttc tcctattaat gaaaaatcca
    28501 ttttattctc gtgttatgtt tcaccaacgc ctgatgtttc tctaaataaa aaagccgacg
    28561 aaccaaataa tcgaaatttg atcattttgg ttcatcagct tgttcccaaa cctttgtatt
    28621 aacgataaat agctggattc gtaaaactat cacttggatc atcactgctg gaagaaaatt
    28681 cggtgataac cgcgcctgtt gcacctgcct ggaaccagtg tttaatattt tgttcgatcg
    28741 tgtactgatc tccagcgtga agtatgattt ctttttttgc cgtatagtaa cgttcttgcc
    28801 cctttggaat aatacaggaa agtttttttg tttcttttcc ttcgacataa agatatacta
    28861 agccttttcg acaacgaaag gtttcctttt ttccttcatt ctcatctcga ggtgggtgcc
    28921 gatgctctgg acaagtttga taaggcaata ataccagttc tttcccacag tatcgctcat
    28981 tattttcata aacaaataaa ttcaatcctt cagtctcgat tgctcctaat ccaaaatctg
    29041 tatattcgat tctttctaat tctgtttctt tcaatactac tcctgaatct aggaacattt
    29101 gttgtactct tttcttgtaa tccattctgt tcctcctaac tgattgtcaa gtcatcccaa
    29161 gatatctctt cttcctcttt ttcttcttgg atgacttctg catttgggtc aactggtttt
    29221 ttcaataata aaatagttat tcccgtagca aaagaaccag ctaacaatgc accaatgaat
    29281 gcccatggtc tggtcatcgt agcgactgca aacattcccg atgccggaat acggctatct
    29341 gcgccccaaa acatgctcaa tccaccgccg actgccccac cgactcccgt tgctatgaca
    29401 ttgcgtgcca agtcgttcaa tacgataggg aaacatccct ctgtgatctg acagatcccc
    29461 ataggaaaag cggtcttcaa tgtatcgatt tcttgacgat tgaatatatt tttacgaatg
    29521 attttcccta agaaataagc gatcgtcaag ccgaatgggg ttaccatcga agctaaaatc
    29581 aatacagtga ttggttcata gattccttct gaaaatcgtg ccacaccccc ttatccagaa
    29641 taaatggtaa tccagaaaca gccgggtatc tgcggtaata agcctaacca aacgaaaaat
    29701 atgagaagct aatatgagaa gctatttttg tttggctgtt cttattactt gatgcagggc
    29761 agctttttca caacctcttt ttttatttat gtttcataat caatatggta aggatgcagc
    29821 tccgtatggt agaccgcctc cgaatattca atcatttccc caatttgcgt agacgatttc
    29881 cgtatccgtt tgatgccgat ctgtgcgtct gttttcagaa tttcttgttc ttcttctgtt
    29941 aaaaatactg ccgagaaatc atcagaaaat gagtcaatag tatatccttt tttcgtcagc
    30001 aaacgataca aagattcttt gccaaattct tctctgctga attgcatcat ttcttgtgga
    30061 agataatgaa caaaataaat ataaggctga ttgttcaaat aatataagcg cttaaaacaa
    30121 acagcttgct caccgaaaaa ggaaaacaaa ggatcttcct tctttatatg gaccaattgc
    30181 aaatccagcg tttctttccg gacttcatat cgggagttct ccaagatttg cgtaaagctt
    30241 gccgctttgg ataatcgatt gtaaggacga ttgcttagaa ccgtcgtccc acgaccactt
    30301 ttctttgcga catattcatc tgatgccagc agttcgattg cctttcggac agtgattttg
    30361 ctgacttgaa acagttcttc taattcactt tctgtcggta acatcgaacc gactggatat
    30421 tttcctgaga aaatatcttc tttaatttta tctgcgactt ccaagtatag tacacgtgtc
    30481 cttttcataa cgtcaccctt tgctttacta ttactaaaag aatagcacat aaaaaataaa
    30541 aaaagaacac aaatcacatg tgagaagtgt gttctttttc attcagctgc tttaattaca
    30601 agtttacgcc atttgaggca attacttctt tataccaatc aaaagatttt ttctttgatc
    30661 gattcagtgt cccatttcct tcatcgtcta gatccacata gataaagccg taacgtttac
    30721 tcatttctcc tgttgatgca ctgacaagat ccatacatcc ccaaggcgta tagcccatca
    30781 aatctacacc gtctgctact gcattagcca tcgcttcgat atgacgacgt aaataatcga
    30841 tccgataatc atcaataatc gtgccatcct cttccatatg atcaatggct ccaagaccgt
    30901 tttcaacaat gaataatggt ttctggtaac gattgtataa ttcattcaat gcgattctca
    30961 gcccttctgg atcgatctgc cagccccatt cacttgcctc aagaaacgga ttttttactc
    31021 ctcccagcaa gttcccttct gaagttgctg cttgtggatc agtctcattg attgccgtag
    31081 acatataata actaaatccg atgtagtcca ctggatattc ttttagcaac tggaagtctt
    31141 tttccgtttg ctctaatttt tccggatcga ctccatattt tttatgggta cgcgctgtgt
    31201 atgcagggta ttctccacgt acttggacat ccgtgcagaa aaaattgaat tcttggtttt
    31261 ggatcattgt tgctgcctga ttgactggat tggcatcgat gctgtaagtt gttgcataga
    31321 taatcatgca gccgatttgg atatccgaac gcaattcgtg gccgattttt acggctttgc
    31381 tacttgcaac gaattgatta tgccatgctt ggaaaatatt ttggtactct cctgctccat
    31441 tgctttttac taatccttga cttaaagctg gaaagtgaaa ggccgaattg atttcattga
    31501 aagtcatcca atatttgact ttactgctgt atctctctaa tactgtctga gcaaatcgtt
    31561 catagaagtc gatcagtttt cgatttttcc agccaccgta ttcttttgcc aaatgaagag
    31621 gcatttcgta atgagaaatc gtgatcacag gttcaatatc atattttaag cactcatcaa
    31681 tcagctgatc ataaaattct aatcccgctt cgttaggagt accttcgtct ccatttggaa
    31741 aaattcgtgt ccaggcaatc gaaaaacgat aacatttgaa tcccatttcc gcaaacaagg
    31801 caagatcttc tttgaaacga tcgtaatgat caattcctcg atgattcggg taaatatatt
    31861 tttcttgatc aatcgtccag tcaaattctt cactgccgat aatcgcaaag cgctgcttac
    31921 ctccaggcat agcatctgca acggatagcc cttttccgtc tcgatcataa gccccttcta
    31981 attgattggc agcagttgct ccaccccata aaaatttttc tgaaaaacgt gattgcatcc
    32041 tgatttcctc cttattttac aattgccaga acatcttcgt ttgcaataat ctctttttgg
    32101 tctaattcaa gtatatcggc aaatgcatca gtattcgtaa tgacaactgg agtgattacg
    32161 ctatagccag ctgctctaat tgcttcgatg tcaaaacgaa tcaataaatc tcctgctttg
    32221 acgagatccc cttgtttgac taagatctca aagccattcc catttaattc tactgtatcc
    32281 atcccgatat gaatcaaaat ctccgctccg tcagtcgttg tgatccctac agcatgtcca
    32341 gttggaaaaa tagtcgtgat ctctccgtct gcaggtgcaa ctagttctcc tacttctgga
    32401 tcaatagcga taccttttcc catcacgcca gaagaaaaaa cttggtctgg tacttcactc
    32461 aatggcagta ctttacccgt taaaggactt tttaaggtat gccgtgctga agtaatcggt
    32521 tctcctgcat tcgcatgttt gttttctaat tgattgtctt gtgtttgttc gtcaaatcct
    32581 aaaatcaatg tacctacgaa tgcaagaaca aaagcaattc ctgtagctat tactgctact
    32641 gtcacatttg actctacacc atccaccgta ttaatgaaag tcggaatcgt caataagctg
    32701 accaaactgc tggagaaagc ttttactccg gaaaatccga taatagctcc accaatacct
    32761 ccagaaatac aagcggcaat gaatggtttc ttcaaaggta atgtcacacc atacacagtt
    32821 ggttcagtga ttccaaataa cgaagtcact gtagaagaaa tccctaatgc tcgaagtttc
    32881 gtatcttttg ttcgcaatgc tacagctaaa gcagccccac cttgtgccaa gatggctgga
    32941 agaagcattg gcatcaatac atcaaaccca tattgttcga tattcaaaaa catgatcggt
    33001 acgaatcccc aatgcatgcc gaacatcacg aatacttgcc ataaacttcc catgattaga
    33061 cctgctacga ttggactaaa tccataaatc gagttgaaga gaccgcctaa agcattaccg
    33121 gcaaccgtcc cgattggtcc taaagcaaga aatgttaatg gaaccatcac tactaaaacg
    33181 acaagcggaa ctaaaatcat ttgcagaaat tgcggaatca ctttttttac gaatggctct
    33241 aatttacttt gaacccatac ggctagaatg attggtatga cagaagaagt ataaccagat
    33301 ggtgaaagaa tcactgggat cccaaagaaa ctgatagctt ctcccgcacc agcaactgct
    33361 gtgatagctg gatacacaag tgccatagca attgctactg ctaaaaactg gttggctttg
    33421 aactttttag ctgctgtaaa agcaagcatg acaggtaaga aggtaaagac accatctgct
    33481 gcagcaaaca atatttgata agtaccgcta tcagctgtca gccagcccat caccgttgcc
    33541 aatgataaga atcctttcaa taccccggcg gctgccatcg cccctagaaa aggtgtaaat
    33601 atactagaga taatatcgat cagacgattc aaaatatttt tggactcttc ttttccatcc
    33661 tccgaaactg caagaccttc ctcatccacg atcgattgat aaacatctgc tacattactg
    33721 ccaatcacta cttgatactg accgccactt tgtacgactt ggatcacgtc cgggtcttct
    33781 tttaactttt gcgtatctgc taaagattca tcttttaatc tgaatcgcaa ccgcgtagca
    33841 caatgtacta aacttttgac attcttttgt cctcctaccg cttcccatac acgacgacca
    33901 actgcttgat tatccattgt tttttccttc tttctttttt atttaaaaaa taaaaaccca
    33961 gattgaaaaa aacagtcaca aacattcgtg aacctatttt ttcaatccag gttttgcctg
    34021 ccatacagta acaatcctta tgattggatg ctttttttct cacttactac tctttgaata
    34081 tgaatcgtta aataaatctg ctctgcgatc cccatttcct gtttttgcgt ttgtcgaaga
    34141 tactcattga tccgttcgac acaatgaaac gcttttggat actttccttg aactaatgcg
    34201 tagagaaatt catcttgctc gtcagatcct tcccctttga gataacgctg ggcaaaaaac
    34261 tgcagatgag taatgatacg ctgataattc aaagattctt catcgaacac gatgccgaag
    34321 aatttactga tgatactcag tatatctctt accattgtgg tagcggtcat cgtcacttgc
    34381 atgtcttcgt ttccttgttg gctattcaca aaatgaaagg caataaaacc ggcttcatcc
    34441 tcagaaagtt ccacacccgt cttttgtttc acgaacaaaa gagcctcttt cgctgcttga
    34501 tattctttcg gataaaattt ttttgtttca aataataatg gattaggcag ttggatattt
    34561 tcttttgctc gtgtgatcgc ataatgaaga tgatcggtca atgtcagata aatattaggc
    34621 gaaaattcaa cttttagttt atcttcagcc agttcgacta cttgtttgac ccattcgatc
    34681 tcctctgccg gaatatcagc catcagctgc tggaattggt ttttagcaaa agaatctctt
    34741 aaaacaaatt ctttttggac cgcttctggc gaaatctcgt ccccaatctt tttttgaaaa
    34801 gctagtcctt ttcccataca aacgacttct tccccgaatc catttttcga aatgacgaca
    34861 ttgttattca aaattttatc aattttcatt ttgcttcgcc ctctcaagaa aaataaaaaa
    34921 acctagaatt cgcctactgt ttcttagctg aattctggtt ttgcctgccg tacagtaaca
    34981 atccatttct tattcaaaat catcatacca tcgaattttt atttatgcaa accttttcat
    35041 ataaaaaata aaaaaactgg aacacaagtc tatctagaaa acaaccaaat cagagatgca
    35101 cctctttgcg tttctctttt tttcagcaaa ttggtttttc cttatcgatt catatccttt
    35161 ggctgttttt aatctgtaac gacttatgtc ccagtatcct aaaatgtttt tgtctctaga
    35221 ttgaaagcag atctcatatc atctgtcgca tcttttatcg atgtaacact ttccagttct
    35281 ccttgtacaa ctagtcgcgt gacggcgtcc atgtcgccac aagtaattag tgtgacaatt
    35341 tcttttccct cgacttcatt cagtaattgg gtatctgtag gagcaacttt ttctttaaaa
    35401 aatgttttgt atgtatacac attttctaaa tctgtcaaat agatcttggc acccatctct
    35461 aaattttcta gcggtgtaaa cagcaattca gggttcgttg cacgatggct tgctaaggca
    35521 taatttcctt ttcccatttc ttgatctgga gataatgttc ctgctccgta aagtagtgac
    35581 gtattatcca agcctttgaa aaccggtaaa ttgattgaaa ctgaagggac tgcgatacta
    35641 gcaatcactg gtagatctgt tcctctcatt tgcgacctca tgaccccttc tgtcgtcatt
    35701 ggttctaccg catcaaagtc aaaactgaca tctttatcgt tattcttttt cagatcttct
    35761 tttgttacat tcgctatagc atatttatct cctgtctctc tgacaaaata atccttgatc
    35821 tgttcattga aaatcaaagc tagtcctact aataacaaga ggaacaagag gatattgact
    35881 agccatcttt ttgcttttcc tttttttttc attttctctc cctccagact cattttactg
    35941 tttttctttt gctctttcca acagccgaat gacacatttc tacaactctg tgtatttttt
    36001 tcgtacacct gcgctttttt ctacaggata tttcaaatta tttttgatca atttttcttc
    36061 aatgatctca tctagatcca ggtgaaggtt gtctgccatc atgtatgaat agatcaatac
    36121 atctgccagt tcttctttga ttcgttctaa ttgtgtttct tttacttctt ccggcgtttt
    36181 ccattgaaaa agttctaaca attcagatgc ttccaaagaa atagagatag ccaaatcttt
    36241 ttcgttatga aattgtcgcc aattacgttc atctctaaac tggttgactt tttccatact
    36301 attcatttgc ttgccttctt ccaatcactt cttacttgat taatcatacc atttttttac
    36361 ataaaaaata gatgatgctt ttaaaaaaac tcctgttttc ttttatttaa aataaatgtc
    36421 atagaaaatc aataatttag gtagccacca tgtgtatgca gtagcgtgtc ttcttccctt
    36481 gaggcttttt gtttttcgat acgttcttct tcccaaacag acaacgctac tagaatctct
    36541 cttaatgatt ttccttcttc ggtgagcgag tactctactt taggcgggac ttggttatag
    36601 gcttttcgat ggatactttc atcttgttct aactctctta actgctgggt cagcattttt
    36661 tttgtgatcg tagggatttg cttgcttctc cacgcctaaa ataagcgata ttgctcttcc
    36721 ctttatctgg tgtaagcaaa gcagttagca ttttgacgat cgtgggttcc gcttttcact
    36781 tcttatctac ttagtatcat gaagtatact ttcgtactaa tactaagtag cggaagtgtc
    36841 aactactttg tttaactaca tagcaaaaga aacagaaggg tgacaacggt catcacgctt
    36901 ctgtttcttt tgaatatgct gtgttgttgt ctctatctcc gtgtagactt tcctcaaact
    36961 tatcctttga cagtaagtca gtaggctgat ttgctctttc tagatgccag atacatttct
    37021 acaaaaaaat agtgattctg ttttgaaaat tcgattttta gttctgcatt ttcgtaaaca
    37081 tccaacattt ttttcgcact gtatagacct aacccgccat tttttttaga ggtttttcct
    37141 cttttgacca tctccgatag cgtcaaattc gttggatttg ccttgttcgc tatactaaaa
    37201 cgtgatccct ctttttcttc cagcagattg atcgtaatcg gactctgatc ggctacacga
    37261 tgatcgaatg cgttagaaat aaaaatagat aaacagcgaa taaaaacaac cagatcaatc
    37321 gggattgttt tcacttcgac aggaataact acttggatcg ggattttctc cgattctgct
    37381 ttttctagaa attttaaaaa gacacccctg acagctgggg atacaatatt tgttagctgt
    37441 tgtatttgcg gtttttcaaa aatagctgca gaatgatctt ctaatatttc taaaaattcc
    37501 aacgtttctt ttttattttc ctgaagagta atttttaatg aaaacagtag acttttataa
    37561 tcatgtttga attcctctag atgatggtaa tattcttcat ttatttgata cagttgaagc
    37621 gattcctgat gttgtctttc ttttacttgg aaactgatca acataatgga aaaaaacaaa
    37681 gaaaaaaaac tgatgactat cgacaaaaga gatagaagca gataattaga tgagcggaag
    37741 tgaacacttc ccaataccaa gtaaatcacg ccccagctta ataaaataca aatacctcca
    37801 aaatagtgtt cagttggata agtaaaaagc aagttgagaa atctcgtctg tttgtctata
    37861 ctttttacta atagatagaa aataaatgcg ataagtagtg caaaaaaact tgctgttcca
    37921 agatgtctct ttcctaaata atccatcaga tcaaaaacca gaaaaaagct gagtccagtg
    37981 atagcaaaaa aaagattact gatcaaacag ctgataaaca ggtttttcgt agtaaaataa
    38041 aaaagaaaca tcaataataa gccaattagg taaggaaagc tcactttagg gataggaagt
    38101 aaaagtgtca ccaccatcaa agctatacaa ccaaagctgt tttttactag cagttgtttc
    38161 gaaaagaata aatagatacc taaatctaaa atcaaagtaa aggtcaaata aagtgtcact
    38221 gttgcgacca tcttattcct ccattgtttt gtttcaaaat gtacacatat ttttttaata
    38281 ggagcctgca tatgaaaaag tattttatca tagaagataa ccagtttcac agcgaatgga
    38341 tcatcagaga attggtcaat catcatatcg agaatatcgt gcagctcact tctatctctc
    38401 aaatcaatca gttgatccag ttgggcacta ttgataatca cgatgttttc tttatcgata
    38461 tcgacttgaa gcaatcactc acaggtattg atgtcgccga acaaatacgt aaaaaaaatg
    38521 cacatagtaa tattgttttt ttcaccgctt atacgaattt tgcagtagag atcatcaatc
    38581 ggaaaatcct tccgattgga tatatcagaa aagacaggaa tttatctgaa caaattcgtc
    38641 aagtgctaga acagatcaat tggaaagaac agcagatcgt aaatgtcgat aaaatcttta
    38701 ttgatcaaaa aggtggaagt ctcgtcctgt atcctcggga aattttatat attgaaagta
    38761 tcaaaggttt gaaaaaccaa gttatggtca aaacaactac agaagataaa ttagtgaata
    38821 cttctttaaa acaattgaag acagagttag aaaagtatgc ttacttttta cttttaaaat
    38881 cttactgtat caacttatcg caattgcaga aaattgattc tgctcattat gtgttagaat
    38941 ttttcaacgg tgactcctta ctcgttggtc gaaagatctt tgaaaagaca aaggaacgtt
    39001 tccatgactt ccaaaaaact gcttcgagtt gatgaataag agctgagacg taagcatagc
    39061 agatttcagg gagtgggcct tgaatcggct ccactccctg aagtcgttga tatgatttta
    39121 cgcttcctct tctgtaggag catctgttaa cgaccatgtg aatgttgaaa cgtagttgtc
    39181 tacagcataa ttggatacag gaacaaataa ttccactgat tgtctccctt gttccacatt
    39241 ctctcctaat gaataaatcc atgtgccaat cccttcattt gctcctgcag ttactagatc
    39301 tactgcctga tctgctggga tttcgattcc ttcagcgcca gttccagaaa cggtagatgg
    39361 cattccactg ctattagttg cgctatttcg aatcacggcg tttttgaatt tcacctttga
    39421 accagttagt ttattcgtat cagatgttgt accaataaat tctgttcgtt tgactgataa
    39481 tttccaaccg gcataatttc cgcttttatc cgttacttgt acgaaattct gtacttgtgt
    39541 ttgtgctcca gtactgtccg ttccgctttg taatgcagca tatactgttt ttgctgtacc
    39601 taacttgatt gttccaaaat caagatctgg agcttggtca atcgtcagta atccggatgt
    39661 tccctgattt ggttcgtcag gtgtaaaagg agtatcagga tcatttggat caacaggagg
    39721 aactggaaca acgtcttcag gatttgcagc atctggtttg gtcacagaaa tcgttccttc
    39781 tgtagtggct gagctcttat tctcagcaaa aacactttgt gtacataata atagacttcc
    39841 agctagaacg gtacttaatg caattgtttt tttcatttct ttttccttct ttcttttaaa
    39901 ataaataatc cagcaaataa gccaataaga atgactccaa caagtatcag ccatcgccag
    39961 tcaaatgttt ctggctgatt ttttaaatca atatcctttt cattcaattg gtccgctgca
    40021 tcatcagtta tttcaaaatc ggtatggaga ttccagcgtt tttctttcca agcacccttc
    40081 acaaccgctt gataatgtcc cggagctaat ttttttcctt ctaatgggac aagtaaatca
    40141 aaatttgtat tgggtgctac atctattttt tcttttttta ttgaaaggta aggctctttt
    40201 gtttcttttt tgtagatttc aaccgatgta gtcaagccga acatataaga agcatttgga
    40261 ttttgaagat tcgccttaat cacatttctt ccatcgcttt gatccgcata agcttttttt
    40321 aatttcaaat ctggggaaga ctctttttcg ctatttcaaa tcaagattgc tttcacttga
    40381 gaaaactgat tgacgacacc aactgtactt ttgttagaaa cgttctcttt tttttcttga
    40441 aacgtgatcc ctcctgcgac cacaccagcc agctcttttt ctggcgcttt cagtgaaagt
    40501 gtctcagtga ccgcactttg aggaggaaca gttatttctc ccactgtttt tgctaagttt
    40561 ttcatatcat aacttaatgt ttcatcaaat ttactttttg attctccata ttcgatcaca
    40621 ccgtttgaat tcgtcgtagc ggagtggatc aatgtctcaa ctgttactga tttatctgtt
    40681 cggttaaaga ccgtgtaggg gatttcctgt gttttcccag gctccatcct tacatttata
    40741 tatgttttgt tcttatcaat ctgattagcc ggtaattcaa aatctaccgc aaaattgaat
    40801 tcggaggcat ggacaggtgt ctgccaaagg atgaatccaa ggagaaggat cataagtaaa
    40861 gagcagttgt ttcgatgact tttattccat attcgattca tcaatcatcc tccttgatct
    40921 ttattctgtc ggcgcatctg ctaatgtcca tgttatctct gctgagtaat taccagctat
    40981 ctgattttct ttggttaaga caagtttaaa cgcccgaccg ttatttaaat attctgaata
    41041 atctgcttgc acattcgttg aattttgtcc tctgacaatt tccagttctt cttcattcac
    41101 taattgatac tcctctcctt tcttgaaata taggacatcc tgcatagaaa atcctgcatc
    41161 atttgtgaaa ggctgagata attttatcgt taagatccac ggatttttcg tttctcgctg
    41221 atcataaatc cataattttt cctgtatatc catttggcca aatgcttctt gtgtcaaacc
    41281 agttgctttg atctgaccaa aatcgagttt ggaaggggca agaaatgaga gaccaccttc
    41341 tactacgatc ttcgtagcag gtgcaaaagg cggggcatca tgataaacaa ctggcgtatc
    41401 acttggattg tgattcccaa tttcatcgtt ggtacttggc ttgttctgca cacccttagc
    41461 agtagcttct cctgcttggt cgtttaatac aatttctaat acatctcctg caaaaagttg
    41521 attttctggg atagaaagaa caaattcccc tgtatcatca atagttgttt ctgacaaaac
    41581 agcttgattt tttttcaatg aaaccaaggc tcctgcttca cctgtacctg tgatcgtgcg
    41641 agaagctgca ttgatcaatg tggtacttaa attagcaggt tcaggaggaa tcacatcgac
    41701 tgtcgttttg gcagagtcca gttctgtcac ttcttggcca cctcttactt ttttagcagc
    41761 aacaacttgc acttgatcct ccgtttttaa tctctcatca ttgggtactt gaacttcgaa
    41821 caagccgcct tgttcgcctt ctccccatgg gttatatcct gccccttcat tttcatctgt
    41881 ttgtccttgc gtgagagcag taatttctac agatgatttc gtcgtatctg cgtaagtaat
    41941 acgtaaagtc acttctactt cgcctgtcca agcatctctt ggctttgcct cgacaccttc
    42001 gggaacaacg acatgcccat agattttttt atctgcattc gttggcactc ttaaggattc
    42061 aatcatcggg agctgattat tggcactgat tcgattataa tttttcattc cggcacctgt
    42121 ctgagcaaat tcatttgtta aacctgcact agggcttgat acgaaattgc ctaagtcggt
    42181 cccattgatc gataagtctg tcatatcaga aaaataatcc gggtcttttt caaagttatc
    42241 gaatgttgcg cctgtttttc gccataaagc gatttctgaa tgggcgatct ttaaagaaga
    42301 atctccattt ccttggaata cccagccgcc tatgccattg gtctcgcttc caatccgttt
    42361 gttttggaaa tcaaaatagg taggagattc taagtccaca ttcaacacat ccccactgat
    42421 gatgccggtc ttatcttccc ctgttttccc gaccatgact aaataagttt tttcacctgc
    42481 cgtaaaattt aaatcaatat ctccagttgt atctacagtt gctccggaat ctgcgcgtat
    42541 atcgatattt gatttttctc cagtgactgt aaaatcagct gaacctggac tttctagaaa
    42601 accagaagcg tcataaaatt ggatcgcttg atttccttga ttgagtctgt tcacgtaaga
    42661 tttgccatca cctgtatttc ttaccctcaa tgagcctcca ttggttactg tcagcttttg
    42721 cgtaccattc tcaaaacgaa ctgcgctgga acgcccactc tgcttatcga tgtcgataac
    42781 tgatccggct ccttctacga tcaaagaaag gccttttcct acaaaacgca tcccattgtt
    42841 cccgggttga tcgtcatctc cagccatttt gaccgagatt tgtccaccac ttgatacatg
    42901 gatttgacta gaatctcctt gcaagcgaaa tccgcccgta gttgctgtat tgatggtgat
    42961 tttcccacca ttcgatacag tgactttcga tcctgaacct ctcatttgga tgattccgcg
    43021 attgttgtca ttggtaatat tgatctttgt atttaccgaa aattcgcttc ccgaaccact
    43081 gacttcaaac atgacattac caggtagcgt atcgactgcc tctccttcat cgctaacgcc
    43141 atctgcccga tcataatcaa gagagacctt tgaaccgctt aagatatgga ttcctggcgc
    43201 tgtttttcca ctaccagtct catctcctga atctagaaaa ccgtagaatt tccctagata
    43261 cggtccataa agttgactac cattgatcac attcaattga tagcttctac aaaaataggc
    43321 tttacccgga gcggcattca gtccttcctt cactggttgg acatccaaca caccggaaac
    43381 accatctaat gtgacagttg cacgaggagc gtaaatcagt cctaatttgg acccatcata
    43441 caaatcaagt gtcccggtaa attttatttc tcccgtaaaa tgatatttgc ttccccaaaa
    43501 atcggtcata taagcaatga taatggcatt tccatcgata tttggtgtca atccacctgg
    43561 atgtgcagct gttcctttaa aattctggaa ctcgatcgac tgaggtatct cattgatata
    43621 aatatggtgt gtgccgaaat tgtgagcgaa tccaccaaaa tcaataacga tatctcgttt
    43681 gatctctaat tccctgtcta aagtcaaagg ctgaatcagt cggatcttag ttactgattc
    43741 gtctgcgaga agctgcgcca gttcttctgt tgtggcagct tcgctgtacc catccgctga
    43801 aacagctctt gccagtgccg cttcactgct atcagacgtt tgttcagcta cttctgaggt
    43861 ctcacttgtc ttattttctt cttgcctttt attagtagaa gcctcacttt gagattctgt
    43921 agtttcagaa gtaatcgatt cttctgaaaa agtagtcttg tcaaaacttt gattctctga
    43981 ttgcgttgat tcgtttgttt tctctacatc ggcaaaaacg gatgtcacca tcaagagagg
    44041 gaagacaaac aaaatcgacg caatcagctt ttttacacat tgattcattc tccaccatcc
    44101 tctctgacgt tttgacaatt ttattttatc gttttaatct atttccaatt gtactttcat
    44161 atttaaaata tgtattttta tggaaaaatt tttctattag gtgtaaattt cttttttgta
    44221 caaaaaaaag gctgtgacaa aagtcttgtc acagtccctt atcccgaaca agcggtgttc
    44281 tcccgccaac tcctcggtca caacctccat tttaacaata aacctgtaaa tgtgagggca
    44341 atactttgat tgtcacaggt aatttatccc cttcatctcc atcaacattc gtcgtcaatt
    44401 cttcctcatc agctaatgac acaactaatt gctcacaagt aaggtaggct agatttttcg
    44461 tagattcatc tactcctttt aataggtctg gcaatgtttt aagcgtatcg atcaaagaag
    44521 aatcttttaa ataaaccaaa tggagcttac catcatccac ttttgcattt ggaagtaatg
    44581 tttcaaaacc gccgactgag ttagttagtc ctatcagcaa ggtactgctc tcaatttctt
    44641 ccttctttcc atcaacttct acgtgaaacg agtaggattg tgtggaagct aactgtttga
    44701 ttcctgacat gaaataagct agttttccaa atttcgtctt cttctccgca tctacatcat
    44761 tgattgattc agggatagag ccaattgcga cgacattcat aaaatagtcg tcatttattt
    44821 ttccaatatc caatggcttg actgattcaa tcgaaaaatg attgatcgct tcctcaggtt
    44881 ctagcggtat ccctaatgct cgagccaagt cattcaccgt acccaatggg aaaaatccga
    44941 aatttggccg atgttcttgt tcagcgattc cactgattcc ttcgttgact gttccatctc
    45001 cgcccatgac aaacacacta tgataccctt ccgtagccgc ttcgcgagta aagttttttg
    45061 catcccctgc tttttttgta tgcaagacga ccacttcatc aaacaccgat tccaattttg
    45121 ctatcgctaa ttgctcaaat tcctttgctt gttcaccgcc tgaactgggg tttaccacta
    45181 ataaaacttt tttcatcact ttctttccct tctgattgat ttctttaata taacgatagc
    45241 ataaagaaaa aaattaggct gtgatgaagt actgttcatg aaacattcat ttattttttg
    45301 acaagataaa acatccatac tatgaaactg aggaaaatta aaacaatgat ataggaaata
    45361 aaagaaaatg ataggcattg tatacctaat aaagtaaaaa tcttaggtgg cagataaaaa
    45421 cacaaaaata gcaagagaat gtaatagcgt ttcttccact ttttgttatc agaccttata
    45481 gcgatcagag gaataccaaa tgcataactg aaaaactctt gatgtactgt taatatgtca
    45541 cggccttgaa taataaatgc gacaatcccc gctataatta gtgtgcctaa caccaaaacg
    45601 gaaaattgat gaatatattt tatatacaaa tgatccattg tacttcctgc ctttttattt
    45661 gtgagaaaaa caaatccgta tacgtgaata acttctagaa ataaaagaaa tttgcaaaac
    45721 cactccattt atctacttct acgtgcattt tttgatattg ttttctttat ttaagattat
    45781 acagaaaaat atctagggtc gctggattct aagtaaaaaa aatttttaaa ataaaaagaa
    45841 ctaaatcaag tagtaattaa actactgttg atttagttct aataaaaaga tttagatgaa
    45901 cagttttatt gatttaaata gttcatattt tttatttata ccgcttattt actacttgct
    45961 gtactagaat ctgaagtgaa tgtactcaaa acattttcaa agtctttgtc tttgattttt
    46021 acattagcgt ctttcaatac ttcgccaatt actttattct ggaaggtact gtcacttaat
    46081 tttgtgtctg ttgcaatttc tttcaattct tttttgtatt tatccatgtc gttgcctttg
    46141 ttttggtttt tcaccatttt aaccacataa tattccgtag tataagttga agcattggta
    46201 gaagtgatca catcagaaac ttgaccatct ttcaacttaa aggctgcttc tttgacttct
    46261 gccggaaccg ttgtagtagt ggaatcaaat ttcacttttc cgccatcttc ttttgtcgta
    46321 gtatcagttg acttgtcttt ggctaattta gagaaatcgt ctcccttatc agcagctttc
    46381 ttcacatctt ttgcatcatc ttcacttgct acttggataa tttgagcttc cacttctgga
    46441 tggaaagatt cccaagccgt ttttaaatct tcatcggtca atttgatatg tttctttaga
    46501 ccttcttgaa aggctagact ttgtttgata ctgtctttga atgtttgttc tgtgtaacct
    46561 gcagatttca attgtgaatc aaatgaatca cccaattgtt tctttgtttg atcatattga
    46621 gaatcgattt ctttggttga tacgtcatct ccatatttat cttcaaatac ttgataaacg
    46681 atcaactgtt gcacagcgga atctgctcct tgcatttttt tcaagctatc cattacttct
    46741 tgttcgctga ttgtaccgcc tttataacta acggctgttt tttcaccggc attcgtacag
    46801 cctgacaata agccagtgcc tagtacgatg gcaagtgcta aaaatctttt tttcatttat
    46861 caattctcct acttttcgtt ttttgcgaat tgctaaaaac aaaggtgttc aagatgaaaa
    46921 tcatcaagaa cacctttact aatctgctcg atacgtcctg aatagatata aggctacaca
    46981 atccagaaag ttcgctcagc agaataaatg tcaagtagca catcacacct taatatacta
    47041 cttcttttgt taccgttttt caagtctatc ttgcgttccg tatttaacgt aactaattct
    47101 tagaacaaat gttatcgatt ttgtttttct tcttccgctg ctgggatatt caaatcagac
    47161 acttttatgt tcgattttcc agacattttt ttgttgtttt tattatgata tatttttata
    47221 caactaaaaa tgaatatatt aaaactacca aaaataactt ttaacgctgt ttcattatat
    47281 gttttttcta ttttatataa acttttggat acttaatacc aaccggttgg attgtaccaa
    47341 catgagaatg tgtcagttct atttcctgtc gcacttgcat aggcccatac tccttttgtt
    47401 gcatttgctg atcgaataga gtttccaact ttcgcttttg caccgtgacg attatagaca
    47461 cgactatagt ggttagaatg acctgttttt ctcgtacaag ttgtatcact ataataaacc
    47521 catcttccag agctatgatt aattgctgtt ctagaaattt cccggtctac tggtaaattt
    47581 gacttaataa tattaccttt agcatcaaaa tgaatctctc ctggctttaa agatttgtaa
    47641 tagatttcac cgtgaactga atttgcttcc acttcagatg acatagcgtt tcctccaaca
    47701 aaacctatcc ctagtgcaca aataataact gcttttttca taaaacgaca tcctttcctt
    47761 tttgattttt aaagcatgat cttcttgttt cctattttgg tcagatatgg atcatgcgtg
    47821 actacgataa ctaacgtacc ttgggaagct tgttgcgata agatttcaac tactttatcc
    47881 ttatttcttt tatccaatga cccagtcggt tcatcggcta aaatgatttt gctattcttc
    47941 aataagactc tcgcacaggc gattctttgc ttctcaccac cagataatgt gtagataggc
    48001 gtacttagct tcttgtttat atttactttt ttcaatgcct catactttgc tgttcgctta
    48061 tctgaaacat ttaaattcga aaacttcaat ccaatatcta aattaaaatc gattgtttca
    48121 tattcaatca acccaaaatc ttgaaaaaga aaagatatgg tatttctttt tatcaagcgc
    48181 ttctctctcc cagttaattg tttcgtctct tgatcgaaca aatagaattg tcctgaactg
    48241 aactgatcat tcaatcctaa tatattcaat aacgtacttt tacctgctcc actttctcca
    48301 acaacagtca caagatcccc agcatccgca gtgaaacgat ccaaatgaag aatcgttttg
    48361 tttcgaatga tttttttcgc accttttatc actatcaacg gctccaattg ttaacctcca
    48421 ttcatcagca ataactgact tttcttttct gtagacaaaa taaaaacaac tgaaagaata
    48481 aaatcaatga agctaaagaa aaaaatatta aaaagatatt taggctctct ttctataaga
    48541 aaaaggaaga ttacacttgt cgttccccat ttgatgaggt tcatcatgaa gaaatcttta
    48601 tacgtttcaa agagcgaata accacttgaa cgaaagatag cgattttccg acaattgtag
    48661 acaaaatata tgcataacat gacatagctc aacaagaaga aagaaaagaa agtgagtaaa
    48721 aatatctgta tcaagtaatg aaatgatctg cttaacactt tgacagctat ctcttcagtc
    48781 tgagtatacg gaaatgataa ctgcaagtta tcacgtaact gactttcttc aatcagctca
    48841 aataaccttt ctttcgacaa agagcctatc ttgatcttta acggtggata gatttctccg
    48901 ctgagaatat ttctttccaa atacatactg tttttcaatg tcagtatttc aacaaccgga
    48961 taatgttcga tccaggggat agaaggaata aatgtataaa tgggttgatt gttttttata
    49021 aatagaaatt tcggttcttt ttcactgatt tcttgataat attctgttat ttgcgccagg
    49081 tcatttttta aatctgtatg tctatatcgt tcagggatca atataacagg gtgcgtttct
    49141 ttttcggtta tttggatcaa ccttccagag acatcaatca aaggaaattt cttaagataa
    49201 ttcagattta tttttatccc tctgccaaac tgttcatttt cttcattcaa gtaatctgat
    49261 acattgacta atatacttcc gtttttattc aaagtttcat ataattcctg atctgctgct
    49321 gatgcaaaac gattggaata aataaaatcc acgtggtttt tcccgatggt tactggataa
    49381 aatacatgat agtcctcacc agcgatttct tttggtggtt catgggaaac agctaactgt
    49441 gaagaagaaa aaacgatagt tgctaattcg acattggcaa cggtcaaaag aagagaaaac
    49501 aacaatccaa atgtaaaaag aatgtattgg atatagttga acgcttctct taacgaagcg
    49561 attttttcaa ctaataaaag agaaatcaaa gagataccat atattccgct gaacaagaaa
    49621 acgtacatct ggaacaaata aagaaattgc tccttataat acataaaaat aaaaccacca
    49681 atgattcctg caattatgaa tgtaataatg attttctttt tccccaataa acaccacaat
    49741 acttgatgta atgaaaagtc attattcaac aataaactga tttctttatt catcaataag
    49801 aaaaaggatg ataacaaaag gaataaaaga atcaatccaa tagttaaata cactcgataa
    49861 ttatatacgt ctgtatttga aataaccgaa tacgaatagc tattttcaaa gtcttcaaaa
    49921 atattagtgg cataatcagt gtgaaatgct tgattgaatc gatcagtgaa tagtgaaatg
    49981 acccgttcat aggcttcttt ttctctcgtc atcaagaaaa attcaccttc aaaatctttt
    50041 attttgatcg attcttcaat ggacgttacg cgaaaggagg tattagaata gggtaccttc
    50101 tcgtgagaag atttgacatc cccttgataa tacaatgtca tttcaagctt tggctgtatc
    50161 ttgaagttcc aagatgtatc tacttcattg gattcattta ctgttttttt catataagaa
    50221 agctcagttt ctgatgagac attttcaaat accatgatta gctgctcata ttcttcttgc
    50281 ccaataaaat gttgtggcaa tcgaatcgga gtataagtat ctgtttgatg gaaaaattca
    50341 tttgtccgat agagtacctg tttatttata ctaaccaagg caaaaccact catgataccg
    50401 gtcactatga ttgtgagtaa aactgtgaac ttttttttga ttatcaccac tctcccttac
    50461 ttaaatgatt ctttgataaa atcataccgt ttttcatcaa aaaaacgtat ctatcaagtg
    50521 tataggtcat gtagaataaa tctatatact gtagaatcga aaggagaaga agatgaacac
    50581 cggagaaaaa atacgaactt accgcagaaa ttgtaagctt acgcaaaaag aattaggcga
    50641 aaaaattggt gtttccgata aaacgatttc tagttgggaa aattctcgta caatgccaga
    50701 ctttgaaatg ctgtcacttt tacatcatac tttaggtctg ccgattgatt ttccttctat
    50761 tgaatcagct accgaatcaa tagaaccaac attgccagat gaacctcttg ttaacaagaa
    50821 atcttattca tcaaaacaac ccttctcact caaaaagaca ctatctttct ttctgctcgt
    50881 cttttgtttg gtctatcttt ttcttatcaa ttatcaatac aaaaatgaaa cgatcgatcg
    50941 attcaatcct tttttgaaac cacaaatcgg ctataccaca ctccctgtag gatacgtgga
    51001 caattccatc gaacgttggg tatgtaatga tatctttggc catggtacat ggctgtcttt
    51061 tcacgctgga gaggtagaaa aagagaaaaa ccatgctgta atcaaacaca aaggaaaaca
    51121 cgtcatgaac gttcgcctgc tcacttggga agccattccc tcagattacc aagaaatcct
    51181 cagccaagac tatgacgacg ccttaaaaag aagccctcag gagccagata ggcattaagt
    51241 aggagatgaa cgtagagata gaaaaaatca atgcacatga tcttatccaa aaaacagggg
    51301 tacaaattaa ttgaaaaagc cttgagatga aagttcctaa ataaaaaagt tcagaatgat
    51361 aggtatttct ggcttatagt ataatattta cgccacagcc tcccaatgat tctttttgga
    51421 atcataatca aggatggaca ttcacaaaaa tattttgctc attcgatccg aatagattaa
    51481 cgaccaatct agtaagtaat atagattggt acgtagtcaa gctgcacata atttagatca
    51541 attttagttc ttttttatat ttctatgatc tgctcattta cttttatatg atggcttaca
    51601 gtaacataaa taaatatgat aatcgctggt agtttatcca agagtactca ataaaataca
    51661 aaatggattg ttcaagcgcc tatcataatg ataaaatgaa acaaataaac gatacaagga
    51721 ggaagagact ttgagtaatg gcagaacaat tttttcattg taaaaattgt tcagttgtta
    51781 atctatggga tttcggtagc atgggcattt ttttatagag gaatcacacc aacctggccg
    51841 ttttatctct tgttagtggg aatattagta ggaaattttg cccctcttca ctatcgtacg
    51901 aacttttttc caactgattc tggccttttt cttaaaacaa agacgcgaaa attagaaaac
    51961 attattgaaa tgacaattac ctgtataatc attttcttag ttatattcct aaacgtcttc
    52021 taataagaat ctcttaaaat tagcttgtta cagttagtta cctagtttat ataacacagt
    52081 tatcttatct tccttatcaa catcttttgc caactctttg tcttaaattc gaaacatata
    52141 agcagagcta cgaacaccaa gactgtttcg gctctgtttt ttgcatcaaa ttcactctta
    52201 tatagctgat aatctcggct ctttaaaaga aattattttc gcttcatttt attataaaaa
    52261 ggctaggaac cttgatgtta tcaggttcct agcctttatt taagtattac cccacagacc
    52321 cttccatata gatttttgaa ttacacacta gtttaaacta aaacaaacaa ggaaaaactt
    52381 accatttaat cataaaatta gctcatatg
//
LOCUS       DAFKHN010000013        50916 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFKHN010000013 DAFKHN010000000
VERSION     DAFKHN010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.013"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            77..922
                     /locus_tag="LY912_000729"
     CDS             77..922
                     /locus_tag="LY912_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBM6954444.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1203..2423
                     /locus_tag="LY912_000730"
     CDS             1203..2423
                     /locus_tag="LY912_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBM6954445.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2420..5140
                     /locus_tag="LY912_000731"
     CDS             2420..5140
                     /locus_tag="LY912_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBM6954446.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5124..6068
                     /locus_tag="LY912_000732"
     CDS             5124..6068
                     /locus_tag="LY912_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBM6954447.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6137..7147)
                     /locus_tag="LY912_000733"
     CDS             complement(6137..7147)
                     /locus_tag="LY912_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBM6954448.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7327..7671)
                     /locus_tag="LY912_000734"
     CDS             complement(7327..7671)
                     /locus_tag="LY912_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBM6954449.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7664..8098)
                     /locus_tag="LY912_000735"
     CDS             complement(7664..8098)
                     /locus_tag="LY912_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBM6954450.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8236..8973
                     /locus_tag="LY912_000736"
     CDS             8236..8973
                     /locus_tag="LY912_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954451.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            8966..10177
                     /locus_tag="LY912_000737"
     CDS             8966..10177
                     /locus_tag="LY912_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954452.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10381..11163
                     /locus_tag="LY912_000738"
     CDS             10381..11163
                     /locus_tag="LY912_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBM6954453.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11233..11895
                     /gene="trmB"
                     /locus_tag="LY912_000739"
     CDS             11233..11895
                     /gene="trmB"
                     /locus_tag="LY912_000739"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBM6954454.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(11993..13747)
                     /gene="ade"
                     /locus_tag="LY912_000740"
     CDS             complement(11993..13747)
                     /gene="ade"
                     /locus_tag="LY912_000740"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBM6954455.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            13879..14808
                     /gene="tadA"
                     /locus_tag="LY912_000741"
     CDS             13879..14808
                     /gene="tadA"
                     /locus_tag="LY912_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBM6954456.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14765..15814
                     /locus_tag="LY912_000742"
     CDS             14765..15814
                     /locus_tag="LY912_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBM6954457.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            15811..16089
                     /locus_tag="LY912_000743"
     CDS             15811..16089
                     /locus_tag="LY912_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBM6954458.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16064..16534
                     /locus_tag="LY912_000744"
     CDS             16064..16534
                     /locus_tag="LY912_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBM6954459.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16551..16853
                     /locus_tag="LY912_000745"
     CDS             16551..16853
                     /locus_tag="LY912_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954460.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            16870..17241
                     /locus_tag="LY912_000746"
     CDS             16870..17241
                     /locus_tag="LY912_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBM6954461.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17213..17572
                     /locus_tag="LY912_000747"
     CDS             17213..17572
                     /locus_tag="LY912_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954462.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17744..18751
                     /locus_tag="LY912_000748"
     CDS             17744..18751
                     /locus_tag="LY912_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBM6954463.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18776..19960
                     /locus_tag="LY912_000749"
     CDS             18776..19960
                     /locus_tag="LY912_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBM6954464.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20397..21980)
                     /locus_tag="LY912_000750"
     CDS             complement(20397..21980)
                     /locus_tag="LY912_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBM6954465.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22558..22701)
                     /locus_tag="LY912_000751"
     CDS             complement(22558..22701)
                     /locus_tag="LY912_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBM6954466.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(22923..23402)
                     /locus_tag="LY912_000752"
     CDS             complement(22923..23402)
                     /locus_tag="LY912_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBM6954467.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23475..23759)
                     /locus_tag="LY912_000753"
     CDS             complement(23475..23759)
                     /locus_tag="LY912_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954468.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(23837..24031)
                     /gene="ssrS"
                     /locus_tag="LY912_000754"
     ncRNA           complement(23837..24031)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LY912_000754"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24103..25389)
                     /locus_tag="LY912_000755"
     CDS             complement(24103..25389)
                     /locus_tag="LY912_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBM6954469.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25527..26198
                     /locus_tag="LY912_000756"
     CDS             25527..26198
                     /locus_tag="LY912_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBM6954470.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26164..26652
                     /locus_tag="LY912_000757"
     CDS             26164..26652
                     /locus_tag="LY912_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBM6954471.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26665..27612
                     /gene="prmA"
                     /locus_tag="LY912_000758"
     CDS             26665..27612
                     /gene="prmA"
                     /locus_tag="LY912_000758"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBM6954472.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27613..28377
                     /locus_tag="LY912_000759"
     CDS             27613..28377
                     /locus_tag="LY912_000759"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBM6954473.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28610..30823
                     /locus_tag="LY912_000760"
     CDS             28610..30823
                     /locus_tag="LY912_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBM6954474.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            30834..31280
                     /locus_tag="LY912_000761"
     CDS             30834..31280
                     /locus_tag="LY912_000761"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBM6954475.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31451..32710
                     /locus_tag="LY912_000762"
     CDS             31451..32710
                     /locus_tag="LY912_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBM6954476.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(32799..33746)
                     /locus_tag="LY912_000763"
     CDS             complement(32799..33746)
                     /locus_tag="LY912_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBM6954477.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34140..35432
                     /locus_tag="LY912_000764"
     CDS             34140..35432
                     /locus_tag="LY912_000764"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBM6954478.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35447..37216
                     /gene="aspS"
                     /locus_tag="LY912_000765"
     CDS             35447..37216
                     /gene="aspS"
                     /locus_tag="LY912_000765"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBM6954479.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37325..38200
                     /locus_tag="LY912_000766"
     CDS             37325..38200
                     /locus_tag="LY912_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBM6954480.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38466..40349
                     /locus_tag="LY912_000767"
     CDS             38466..40349
                     /locus_tag="LY912_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBM6954481.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQISNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40424..40708)
                     /locus_tag="LY912_000768"
     CDS             complement(40424..40708)
                     /locus_tag="LY912_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBM6954482.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40698..41432)
                     /locus_tag="LY912_000769"
     CDS             complement(40698..41432)
                     /locus_tag="LY912_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBM6954483.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41561..42184
                     /locus_tag="LY912_000770"
     CDS             41561..42184
                     /locus_tag="LY912_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBM6954484.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42376..43497
                     /locus_tag="LY912_000771"
     CDS             42376..43497
                     /locus_tag="LY912_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBM6954485.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43504..46632
                     /locus_tag="LY912_000772"
     CDS             43504..46632
                     /locus_tag="LY912_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBM6954486.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKAEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTALVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46651..49845
                     /locus_tag="LY912_000773"
     CDS             46651..49845
                     /locus_tag="LY912_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBM6954487.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYAEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKSKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(49991..50698)
                     /locus_tag="LY912_000774"
     CDS             complement(49991..50698)
                     /locus_tag="LY912_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBM6954488.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16655 a         8916 c        10600 g        14745 t
ORIGIN      
        1 ggtataatta gtatatgttt tgtgagaaat ttagacttac aataagcagt gaatttataa
       61 tcaacgtata ggagacatgg atgaaatgaa actaattggt atagatttag acggtactct
      121 tttgaattct gaccagagca ttagtcaaaa aaatgcaaga acaatgaaac atttaccgga
      181 agactgtttt ccattcattt gttctggaag agaagtagaa gacattaata atattctcaa
      241 aaaatctggt ttaaggatac cagcagtagg gttaaatggt tctgttggat ttgatggaga
      301 aaaaaagata tttgagtctt ccttcgataa aaatgatgta aaaaaaattg attctgtcct
      361 atcgaaattt ccaaccaaaa tatatacaaa tctcggaagt tatgaatctc agaattataa
      421 aaataaaatg aaaaaaattt ttcacgaggt agggagtgaa ttttctatca aagagctaaa
      481 ctatgagctt gagtatgaaa aatctatttg ttcaatccct tataataata ttgaggaaat
      541 tatagaaaag gatgctatca gcatttacaa attttttatt tttattccta atcgtcaatt
      601 gaaagctaat atatttaacc atttgaaaaa gatgctaaat gtgtctgtta ctgaatcggc
      661 acctgtaaat attgaaatcg tacctcaaaa tgtatctaaa ggtgtggtgt ttgatcgttt
      721 ggaatcaatc tacaatttaa agaaaccttt gagaatcgcg atcggagata gtttaaatga
      781 cttatctatg tttgaaagtg cagatattag ttttgcaatg ggaaatagtc atcaagaaat
      841 catgaaaaaa gctgattatg tcactgtttc aaatgataaa gacggagtat ctcaagcatt
      901 tgaaagaatt cttaccatat aaactaatta aggtagtata gaacatagaa ttctaaatac
      961 ggaaaaatgg agcataaatt ccagtacaaa tagtacttct tcagtgtcaa acgaagcgaa
     1021 tataacatag atatttagga ttgtgacaaa aatcatgtca caatcttttt ttcgaataaa
     1081 cttatttttt gaagtcggcc atttatcgta atttctttgc ataatacgaa caaattttcg
     1141 gttattgatg aaaaaaaaca ttgaaaatgg tatgataaaa gaaaaaaagg aggaaatttt
     1201 taatggtgaa atttatccat gcggcagatt tacatatgga tcggtcattt gaaggactga
     1261 caactcttga taaaactgta caggaaaaac tattgaagac gaatctgacc gttttatcaa
     1321 atatcattga acaggcaata ataaataacg ttgattttgt tttacttgca ggagataatt
     1381 ttcatcaaaa tcgtccttca ttaaaaatac agaaacattt ttcagaacag atgaaacggt
     1441 tagaaaagaa ccatatacct gtatttataa tattcggaaa tcatgatttc tatcaaaaag
     1501 agcggtattg gttctccttt cctaaaaatg tccatttatt tacatccgaa acggtagaga
     1561 caaaaaaaat aacgataaaa agtggagaaa ctgtctctct cagtggattt agttatcgtc
     1621 aaccgtggat tcaaaaagac aaagtgatgg aatttccttc tagagaactc acagattacc
     1681 atattgggtt gtaccacggg gaacctggcg tctctcaaaa aggaaactat gctcctttcc
     1741 aaccctcaaa gatgcaagaa aagggatacg attattgggc tttagggcat atccatgtgc
     1801 caacggtctt aaatgaaaag caaacaattg tttatccagg tgcgcctcaa ggtcatacta
     1861 aaaaggaaca agcttctaca tctattctac tagttgaatt aagtaaagga agttgccaaa
     1921 tacatccgat taaagtagca gaggtctatt ggaagacaaa ggaaatatca ttgaggaaag
     1981 caagaacgac aaaagaggtc attgttcaca ttcgtcagca gctttcaaaa gtagaggatg
     2041 gatttagttt aattgagata aaattaaaag attatgacca tctcaataca gatgttttgg
     2101 aacggataca atcaggagag ctattagact atttgttaga ggaattctca gataggataa
     2161 atgatttctt tatttggcgt atttctctca tagagaatac tttttatacg aagaccccac
     2221 ttgctgcttc tgctaaattg atggaacagt tatttcaata ctatcagaca cctcaagatt
     2281 tccaacaaat tttaaatgaa gtatatagtc atcaagaagc ggctagaata ttgagcgaac
     2341 tgccggaata tcaagaagaa acacttgaaa aagccaagca gctgcttaat caagattttt
     2401 tatttgagga ggatcaggaa tgaagatttt aaggatcgag attgctgctt ttggaaaatg
     2461 gcgtcaaaaa agttttgact tttattcagg caatcagctg atctatgggg gaaacgaagc
     2521 aggaaaatca acgatttatc aatttattca agcaatatta tttggtttcc cttcaaaagg
     2581 ccgtaaaaaa aaggattata caccaaaaga cggctcagcc tatggcggca aaatatggct
     2641 taaacatcct gtatatggtg aatttgctgt cgagcgctac aagcagcaaa atcgcggaaa
     2701 atcgaaggtg tggctggggg atcaagtggg aagtgatgag ttactagaaa aactgatcgc
     2761 acctttgacg aaagagttat tccagcaggt atttactttc cagcaagagc agttgatgga
     2821 actagatcat ttgagagaaa aagagctaca tgatgcgctg atttctttag gcatcacggg
     2881 cagttctcaa gtattccaaa agcggcaaga atattatcag aaagcacaac aattattcaa
     2941 gaaaaaaggc caaaaattac taatcaatca aaaattaaat gaatggaaag agctgcaaga
     3001 aaaaattcat caaaaacaag aacaggaagc ttattttggc aagttgatcc aacaagaaca
     3061 ggaatacgag tcgcaacagc agcagttatt ggcacaatta aaagaggcga acaaacaatt
     3121 ttcattagcc agacagcaag aacttaattt ttctttatat gaagaatggc aatctctcaa
     3181 aaaaaacagc actacaggtc ttcctgatga gcaacttctt ttagatctgg agtctttctc
     3241 caaacggtat cagcaaacaa atgagcgttt ggaagaatta gaagcaacac tggaaaagca
     3301 tagcgggatg gatcagcagt cagccagata ttatttttat ttagagcagg agcaggaact
     3361 aaaagatctc cagcaacttc aatttacagc ggaacaatta aacgaagaat ggcaaagatt
     3421 acaaattgag actagagaaa caaattcaga attgaagatt ttggaacaaa ggtggcattg
     3481 gcagaaaaat ccgttaccgg aagaattttt atatgaagaa gaatggaagc atcttctggc
     3541 tgaagaaaga aggattgctg atctagaaag ccagatttct gtgcgtctcc aaatagctaa
     3601 agaacagcaa gagatgattg aagcagaagt gaatgacttg gaagagacct atccagcatt
     3661 attacaaaat cagtcagaga tagcaccagt ctcttcatct aaaccgtata tgctgatggc
     3721 tggcggagca ataatcattg caggtatatt tgtaccaatg cccttgaaag tgatcctttt
     3781 actaattggt gcaggcatga ttggctattt cttctacaaa aggcaaccaa aaattaaaac
     3841 taaaaatgat ttctctgaga taaaaggaat gtggcaagaa aaactaggac aacttgatct
     3901 agccttagct caattagctg aagcagaaga aaaacaaaag agaactggag aagaaaaaca
     3961 gattcttcag caagaagtat atcgttttgc ggatcatcgg cacttaggaa agatggatac
     4021 gctcaaactc atgaaagaat atggacagga agtcatagat tatcagaaat tatatggcgt
     4081 atttgagcgg aaacataaaa gagaacagga aatacaagaa aaactacgac aaatcgacca
     4141 aaaatttgag tttgttaaag aatggttacc gatacaagat aagacaattt cagaaaaaat
     4201 ggtattgctt tcccgtttta tacaagagat ggaacagatg aaatttgcca gaagctatca
     4261 gcaaaatact ttattgaagc aagaaatcaa tcaattgaaa aagaaacaaa aagtatggat
     4321 acaagaatac agcgaacaat tgactcaagc aggcttatct tatccttcgg aagtacctgt
     4381 ctttttacaa aaagccaaac aagccgaaca gcagatgaaa agatacaatg aattatcgga
     4441 aatgcttact ccactatttc ctgaagagct gacaaaagag aaattatctg taagactgcg
     4501 ccaactgaaa gaaaagcaat cccaactcca gcaagaagaa aaagaagcaa gtgaaaatcg
     4561 gcaacgactc caacttcaag tagaagagtt gcaaagagac ggcacattgg acgaacttta
     4621 tcaacaagct agccggcaaa aagcaaaatt acaggaatta ctggaggaat ggggagcact
     4681 tgaaatcgcc gggacattct taggtgatct ttcaacagag atgagtgaaa gacaattacc
     4741 ccagttgtta agagcagcag gtgattattt aggtatttta acaaaaggaa attatcagaa
     4801 gatattactg aaaaatgata cactgacttt aacagacgga tatacagaat ttcccatcta
     4861 tgagttatct acaggtacga aagatcagct gattatggcg atgagatttg cttacctctc
     4921 attagaagct aaccgttcga tatgcccgat catcattgat gatggctggc ttcattatga
     4981 tcatcagcga aagtatcaat tagctgaact tttagctaaa tttggagaaa agtatcaaat
     5041 aatttgtttt tcttctgata aagaaatggt aagctattac catgagatga accaaatcgt
     5101 aaaacaatta gaaggagcaa ataatgaaaa aaattcgtga tttagtaatc gatgagcagt
     5161 ttgaacaatt tgtcctgatc aaaagtgcag atgtaagaat cgctaaaaac ggaaaaaaat
     5221 ttattgcttt tactttccaa gatacttcag gtactatcga tggtaaatac tgggatgctt
     5281 cggaggagga aatcaataaa tttacagccg gcacagtcgt ttttctaaac ggtaaaagag
     5341 aggtttatca aggaaaccct caagtaaaga ttcttcatat gcgcttaaca agggtagatg
     5401 agccaggaga gcctagttta tacatggaaa gagccccttt gaagaaagaa gaaatggaag
     5461 aagaaatcaa tcaattgttg tttgagatca ccaatgcgca ttggaatcgt attgttcgct
     5521 atctacttaa taaatatcaa aaacaatttt ttgagtttcc ggcagcaaaa agaaaccatc
     5581 atgcatttgc cagtggatta gcttatcata ctttgacaat gcttcactta gggaaatcaa
     5641 tcgccgatga atatcctgag ctgaatcgag cattgttgta tgctggtatc attttgcatg
     5701 atttaggaaa ggtgattgaa ctttccggtc ctatgtcgac agaatatacg cttgcaggaa
     5761 atttgatcgg tcatctggta ttgattgacg aagaaataac taaagcctgt cttgcgttga
     5821 aaatcagcga agctgacgaa gatgttcttg tattacgtca tatggtttta gcacaccatg
     5881 gcttattaga atatggctca cctgtacgtc caagaataat ggaagcagaa atattacatc
     5941 aaatcgacaa tatcgatgct tcgatgcaga tgatgttgac ttcgattcgt caaacagaac
     6001 caggaaaata caccgatcgg attttcggta tggacaaccg aagtttctat gtaccaaaag
     6061 atttatagca aaaatttatt tttttcattc aaaacaaaaa aagcgagaca taagtcttcg
     6121 ctttttttgt tttcttttat tttgatgaat cagttgtttc ttcagttgaa gattcttttg
     6181 ttgaatcagt tgattttgtg tcagaactct ttgttgaagc tgtagtttca cttgagtctt
     6241 tcgtacttga tgaagttgtt gtgaatgcac tcaacacatt ttcaaaggca tcatctttga
     6301 tttttacatt tgcatctttt aattcttcac cgattacttt agttgtgaat gcattgtcac
     6361 ttagtttagt ttcagtagcg atatctttta gttgatcttt gtatttatcc atgtcattgc
     6421 ctttattttg gtttttcacc attttgacaa cgtagtattc tgtcgcataa gaagtaggat
     6481 ttgttgtagt aataacatcg gagatctcac cgtctttcaa tttgaaagct gcttctttta
     6541 cttctgcagg aatagttgtt gtcgttgagt cgaatttaac tttaccgcca tcttcttttg
     6601 tctctgtatc agttgatttg tctttggcta atttagagaa atcatctcca tcatccgctg
     6661 attttttcac atcttttgct tcatcttcac ttgataattt gatgatttgt gcttctactt
     6721 ctggatggaa agatttccaa gcagttttca aatcgtcatc tgtaatatct acgtgagctt
     6781 tcaagccagc ttcaaaagct aaattgttac gaatatattc tttataagta tctttcgtat
     6841 atccagcagc ttctaattgt gattcaaaag tatcacctaa tgatttcgct tgtttgtcgt
     6901 attctgcatc cacttgctta tcggttactt tatcgccata tttgttattg aatactttat
     6961 aaatgatcat ccgttgtact aaggattggt tcgatgattc aagttttgct tcatcataga
     7021 aatcagatac agtgatcgtt ccgcctttca tcgttgcgat atctttatta gtatcgcctg
     7081 aacaagctgc tagagttaaa acagccaacg cactagtagc tgccaaaata attgattttt
     7141 ttttcattaa aatttgcact cctgtaatta gttattattt ttatatatta actataccat
     7201 atcccatttc ctttaaaaac gttgtcgtgg tagtttcaaa caaaattcaa aatttcatca
     7261 cattcctagg aaatacgcaa acttttctca cttatatagt taaatctgtt gagaaaataa
     7321 tcattattat atttgttcag gatactctgg cagatcagct tttagttttt ctacttgttc
     7381 attgatttgt gtgatacgtg gttcggcttg gaatttaaaa tcttcgatat cttttttgat
     7441 tgcttcttgg aaagcaggaa tcacagattc agctgtttct tttgtttcga tcaatgcgct
     7501 tttaaaatga ttcaggctgt tatttaaatc atttgtcaga gttgttgctt cttccaattc
     7561 ttcgatcagt ttctttcttg tttcattccc gctcctgggc gccaataaca gacctccgac
     7621 agtgccagca gcagctccaa ataacagtcc tttgaaaaag tttttaatca tcgcaggaca
     7681 cctgctttac gattgtttct tgaatagctt ttagttcttc cgatccataa ctatcttgat
     7741 gattgacaaa gtgaatagaa aaatcatcct ctttgctgta gcgagggact aaatggatat
     7801 gtgaatgaaa aacagattga taggctagtt cacggttgtt attcaagata ttaagacctt
     7861 tcatttctgg aaaagctttt tccaatgctt gagcaatctt aggcacacgc gaaaaaacct
     7921 ctcctgcaag ttcgggatca tattcaaaaa tatctgctac atgacgttta ggcacaacta
     7981 atgtgtgtcc tttcgttgct tgagagatgt ctaaaaaagc atagaccttg tcgtcttcat
     8041 atattttata gcttgggatt tcttgattga tgattttgca aaaaatacag ttttccatat
     8101 aaaacatcct ttctataaag aataaatact tcagcttaac tttaccataa gttaaagcta
     8161 ttgtaaggaa aaaaacaaaa taccgtcatt ttcttcgtgg tataataaat aaaaataaat
     8221 ggcggaggaa aaagaatgag tttaattatc gatcatgtca caggggggta cggacatctc
     8281 cctgtgttaa aagatatcag tttcgatgta cagcctggag agatagtagg gttgattgga
     8341 ctgaacggag cagggaaaag tacgaccatc aagcacatta tcggtctgct ggaagcttca
     8401 aaaggaacga tagaaatcaa tcatctatcc ttaaagaaaa atacggaaga atatcgcaaa
     8461 caaattgggt atattccaga gactccttct ttatatgaag aattgacatt gagagaacat
     8521 atcgaagtca ctgcgatggc ctacgatata cctatggata tagcaatgaa aagagcagaa
     8581 aagttgttgg agacttttcg gttatctaat cgtcttgact ggttcccagc taatttttca
     8641 aagggaatga aacagaaagt gatgatctta tgcgcctttt tgatcgagcc ttctttatat
     8701 atcatcgacg aaccattttt aggcttggat ccactagcta tcaatgcatt gcttgaattg
     8761 atggtagaaa tgaaaaaaga aggagccggt attttgatgt ctacgcatat tttagctact
     8821 gcagaaaaat attgtgatcg ttttgtggtc ttacataacg gagagatacg agcagacggt
     8881 tctcttgaga tgttgagaaa agaatttcag ctgccggatt cttctttgga cgaaatctat
     8941 attgctttaa caaaggagca ggcacatgag tagttttttt caaaaacgtt tagcaagaca
     9001 tcaaaagaaa atgatgaaat atatgcgtta tgtattgaac gatcattttg ttttagtttg
     9061 tcttttcttg attggcggtg tgggattata ttattctaat tggttgaaaa ccctgcagcc
     9121 accgtttgca attggagggc tcataatctc tgtattttgg atgctctgtt tattcgtggg
     9181 taagatggct acttttgcag aggcagcaga tattgttttt ttacttccta aagaaaaaga
     9241 aatgcaaacc tatttggaac gagcttttcg ctattcttgc atttttccgt tgatcttttt
     9301 gatattggca tgcggattgg ccatgccatt agtggtggtt agtacggagc aatccttttc
     9361 gatgtttttc gtctatctga tcatattatg gagtttgaaa ttcagtcatc tgcaaatcaa
     9421 gagagcagaa ttgtttcgac tagatcaaca agttattcgt tattggaaat taggctggtt
     9481 tttttcttct ctgatctttt tgtttctatc attttattgg ctaatatggg caggaatagc
     9541 aggtgcatta gtacaggcaa gtctatatta ctggtttttg tggaagcaac aagaaaaagg
     9601 attggattgg gagaaaatgg tgcatgtaga agaacatagg ttgcatcaga tctatcaatt
     9661 tatcaattta ttcacagatg ttcctgaaat tacggcaaag atcaaaagaa gacgctattt
     9721 ggatcctata ttgactcata ttaaaagaga atcaaaaaac acttatcttt acttgtttgc
     9781 aagaagattg gcaagaggtt ctgattttag tggtctttat ttccgattag taattatagg
     9841 tgggttattg attgccggag tagtcgactt ttattttagt ctgattatcg gtttcttatt
     9901 tttatatttg atcggtttcc aactgttacc tttagcgaac cagttccgct atatggttct
     9961 cgttcagctt tatccaatcc ataagaatca gaagaagcag gcgattcagt atctactcac
    10021 atgggtatta attatcgcgt cggttatttt tggtttgatt gctgcagtcg tattagatgg
    10081 gcagcagcga tgggttccgc tagcggctta tttgattgtt actatgctct ttgttaaact
    10141 atatgtacca actcgtttga agaagatgtc agactgaaaa caaagctgtg tagggtaaaa
    10201 atgagaatga aaaatagagc gttgacagta agaatgctgt tcgttctatt ttttttgaga
    10261 aaagctggtt ttttgaatgg caattaaatg aaaaagaacg tatatgtgct tgacgtgtag
    10321 tgttcaggcg actagaataa taagtactgc aaaacaaaga gtaagaggac gggagaatgc
    10381 atgatggagt ttcagttaga ccaagagtgg cggttacgtc ccatcaaagg cgacacagga
    10441 aaaacataca taggcatgcg tgatgaggac aaagtcttta ttaaacgaaa cacgactccg
    10501 atgttggctg ctctttcaag ggaaggaatt acaccaaaac ttgtttggac aaaacgaacg
    10561 gggaatggcg atactttgac agcacaagag tggctggaag gtcgcttgct gactcctaat
    10621 gagattggtc aaagaaacga cgtgattgat gttttgtacc atttacatca ttcaaattct
    10681 cttaaaacca tgctgacccg tatcggtggt cgtgtcatga cgccggagaa gatgctgcaa
    10741 aaatatgaaa aagaattacc ggaagaactc cagaaaaatc aatttctgca aattgtccat
    10801 cgttttcttc gtgagcagat cccgtcaata gataaggaaa acttatcagt agtacacgga
    10861 gatgtaaacc atcgtaattg gttagtatgt aaaaattatt tatatctagt cgattgggat
    10921 tcaatcatgt ttgcagaccc tgcggtggat attgcaacga ttttaggaaa ttatgtgcca
    10981 ctgtctagct ggaatcagtg gctgatcagt tatggcatac gcccgactga cgaaatgctt
    11041 gaaaaatttc attggtatgc ggccatgaat ttgctccaag aaatcaccag atattgcaaa
    11101 cgtgaagatc atcgacggat gaacgaagaa attttacaat taaaacgaat tttcagtggc
    11161 tgaggtttgg cccaaactct gcggagattt ggccagacct ttttaattag aggaaaggaa
    11221 tggagataaa taatgcgtgt ccgaaatcgt ccgggagcag cggaaatgtt agcggctcac
    11281 ccgaattttg taattagtga tccaacattg tggaagggaa aatggaatga attgtttgaa
    11341 aacgatcatc caatccacat tgagattggt atggggaaag gccagttcat cactggaatg
    11401 gcaaaagccc atcctgaaat caattatatt ggagtagaaa tgcaggtcag tgttgtttcg
    11461 attgcactag acaagttgat cgaacaaccg cttcctaacc tgaaacttct acatgtggat
    11521 ggatcagcgt tgacagagta tttcgctgac agcgaagtag atcaaatcta tctgaatttt
    11581 tccgatccat ggccaaaaaa acgtcatgaa aaacggcgat tgacatataa gacttttctt
    11641 gctgtagatg aacagattct tcgtccaaat ggagaaatcc atttcaaaac agataatcaa
    11701 ggattgtttg agtattctct ggcaagtttt tctcaatatg gcatgatcct caaacaggta
    11761 tggttagatt tacatcaaag tcaatttgaa ggcaatatta tgacggagta tgaagaaaaa
    11821 ttttcttcaa aaggtcaacg tatttatcga gtagaagctc aatttcaaga taagaccaaa
    11881 aagaaaagtc tgtgaaacta actttctgct ttcataaaaa cattaatatc cataaataaa
    11941 tctcagaaaa tgaacattac agatgtaatg tattttctgg gatttatttg atttaaaatg
    12001 tatttatttc atcggttttt ccacaaggtg gaatcaattg gaagcgagaa aatgaaaata
    12061 atcctttgtc ggtgatcttc aattcgggta tgacagataa tgttaagaaa gaaagtgtca
    12121 aaaaaggatc aaaggtttta gctgctccta gttgatgtgc tttagttatt aattcattca
    12181 actgttcata gacgatcgaa aaaggttcct gtgtcatgat tccgcctata ggaagagaaa
    12241 cacaagctat ttcctgctgt ttgttgacaa cggtcatccc gccacctttt tgaatcaaaa
    12301 gattagcagc atacagcata tcctcgtcgt ttgtcccaac gacaactaga ttatgcgagt
    12361 catgggcaat cgttgtcgct atcgctcctt gtttcagctg aaatcctttc actatgccta
    12421 atccaatgtt tcccgtttga tggtgacgct cgatcaccgc aatctttaat tggtcttttt
    12481 cgattgaagg aatgaatcgt tcgccttgtc ggtccacttt ttctaccaaa tctttagtca
    12541 ctagactatt cgggataatt tcgatcacat gggcttgtga agaagaaaga agcagctcta
    12601 acgaatgtgg atttaatggt tgagcgttta gttttggcag acaacacgta tatgaatttg
    12661 aatgatcagc aaataaatgg tcttggagtt gcccagattg aacaactaat gttcccttat
    12721 agaaaacttc atgaattggc agcttggtaa gatcgtctgt taagaagaaa tcagcttgat
    12781 acccaggggc aatcgcacct agtgttttca aatcaaaaca ttctgctgca ttcaatgttg
    12841 ccatctgaat ggcttgtaat ggatcgattc caagtgcaat agcttgacgg acgatatgat
    12901 cgattgatcc ttcttttact aaatcattga tcagtttatc atcggtgaca aagaagcatc
    12961 ttcttgaatt ttcaggtgtg atcgccggta gtagcgatgc cagatctttt gcaacggtcc
    13021 cttctcgaac cattaaatac ataccaagat ccaaacgttc tttagcttct tttgcagttg
    13081 tagcttcatg atccgtccga atacctgctg caggataaac atttaactct tccatgccga
    13141 taccagctgc atgcccgtca atttttttct tatgctggtg catcaattgg atcttttcta
    13201 ggatgtctgt ttcattattt gctactgctt gatagttcat gacttcagct aagcctaaaa
    13261 cttcgggttt ttgtaaaaaa ggggctaatt tttttgcatt taaatttgca ccattggtct
    13321 caaaaggggt tacaggtaca caagaaggta gcataaaaaa gatattcatg agtgtttgtc
    13381 ttgcatcttc tatcataaac tcaagacctg tactcccagc aatgtttcct atttcatggg
    13441 gatctgtcac tacagtagta actccatgaa gcaaggatac ttttgaaaat tcgcttggtg
    13501 ataaaagtga gctttcgata tgcacatggc catcgatgaa tcctggcact agatattgcc
    13561 cattagcatt atgtacgctt tttccttcgt attcaccgat tcctacgatc attccttcgc
    13621 agattgctac atctttttcc atgatttctt tcgtaaagac gttgacgatc ttagcatgct
    13681 tgatcactag gtcagcaggc ttttttttac ttgctacttc gatatatttc cttaatgttg
    13741 tttccaatgg agtgcctccc aagataaatt tttataagta taacataaat tcggcttttg
    13801 ccaatatttt tttgtaaatt cattttattt gaaacaaaaa gatcaaaaag acgtatgttt
    13861 tttgtggagg ggagaataat ggaaataaaa cgattatcgg atcaaatgat aagtgaaagt
    13921 tttgccaaac atgcccaaga cgtatatata ttgccagctt cagaagtatt ttacatctat
    13981 tttcgctatg gaaaaaaacg aacattctgg aagaaagtct cttcggcaga tggacagcaa
    14041 ctgatctcaa gatttaagta tttgggacag atggatatcg gagaaaaaag aaaagctcag
    14101 ttaggtgcat ttacttattc tttagaaaaa caggaagttc gtctgcggtt gtcttctgta
    14161 ggagattacc ttcaacgaga gagtttagtg attcggctat tatacggtac ttttgaaaca
    14221 ccccatcgtt gctttagttc tcgagatttt gcaactattt tacagaaaac cgtcagacgt
    14281 ggattatacc ttttcagcgg accagtcgga tcaggcaaga cttctctaat gtatcggttg
    14341 gctttggaag aaaaattgca agtgattact atcgaagatc ctgtagagat agaagaaccg
    14401 ttttttctgc agctacagat caatccgaaa atagcacaga cttatgatac acttttgaaa
    14461 ctcgcattac ggcatcgtcc agacttgcta atcattggcg agataagaga tgaatcaact
    14521 gcacatgctg cggtaagagc agcactaaca gggcaccggg tttttgcaac cgtacatgca
    14581 cgcaatcttg aaggtacatt ggtcagaatc catgaactga caaagaaaaa agaagagcta
    14641 tctgaatgtt tagctggtgt catttatcaa gaacttttgg aagatgccaa tcaccatcct
    14701 tctgttttat ggagttatca atttatggag gaagaatcag taaaaaaatc atgggaggaa
    14761 agttatgaag aagctcagga aaatatttgg cagtcagaac tattctaaag gattaacaag
    14821 aagccagcaa aaccagtttg cacaaaccat gggagaactg cttttatctg gttttagtct
    14881 gcaagaatcc ctttatttat tactcacgat ccgttcgttt ccacctgtta ttttggcaaa
    14941 tatccaacat cagctaaagg aagggcaagc gtttagtgag gtactttcgc aaataggata
    15001 tggagcagag caactggtac agatcgagtt agctgaacgt catgggaatc tgccgacaac
    15061 tttgttggaa attgccaaac agtttcggct tgttgaagga tttcgcaatg atttgaaaaa
    15121 gctgcttgca tatccgatgc tattgctcac ctttttgcta ggtatcttgt ttagtatgcg
    15181 gttgttcgtt ttgcctcagc ttattggttc aggaatggtc atgcaagagc attggggtat
    15241 tcagctgata caagtctttc attggtatgt tctactattc atcctagcgg ttactctatt
    15301 ggctttacta gtaaggtatc gtctgatgaa gttgtctcct gttgatcaga gtgaatggat
    15361 aagcagacaa ttattgattg gaccgatata ttccttgtat caatcggctt atttgtcact
    15421 agagattgga aagctttttc atgaaggttt cgaattaagg caaatcatag tctgcttaaa
    15481 ggaaacgaaa caagaaagtc tgattcagca tcttgcctct aagttgattc aaggattgga
    15541 ggcaggtatg tcattggctg agcagttcca gaattatcgt tttctatcag aagaattcag
    15601 taaaattgtt ttacagggag aggcaaaggg aagtttaggt aaagaactga ttttttacag
    15661 cgaatggaca agaaaacagc ttttcaaacg tcttcatcac tggatgcatt ttattcagcc
    15721 aatcattttt ttgggcgtag cggctttgat tttattagtt tatgccgctg ttttattacc
    15781 tgtttacgga agcatagagg aggttttgcc atgaaaaaga gaaaaatatc ttattatagc
    15841 ggttttacat tgatcgaaat gctaatcgtc ttactgatca tcagtgtatt agtgttgttg
    15901 ttcgtcccta atttgtcgcg ttataggaat catgtagacc aagaaagtcg tgaagcgatc
    15961 atccagttgg tagacacaca aaaagagctc tatgcgcttc aaaataatgg aagagttcct
    16021 actgtggagg aattgttgaa tgaaggctat atcaaacgag aacatgcaga aatctatcag
    16081 cggccttgaa ggtaaggttt tagcatcagg atatacgttg tttgaatcac tcttactgat
    16141 tttattactt acaacgatcc tttcttttcc agttctcgca ttttctgcat ggaagaatga
    16201 attggcagtc tatcaatttt tcggccaatt tgaaaaacga atctattcta cgcaaaaaat
    16261 cgctattgtg aatcagatcc aaacaggctt ttattggaat agtgaagaga atcaaatcat
    16321 ttttcatgtt ccgaatccag ataaaataaa ttgggaagta ttagatattc ctgatgagat
    16381 taccttgaaa cgccatgctt ctattacttt tgctgctaga accgggaatg aaagttcact
    16441 aaaagcttat caattttatt gggaagaaaa agagcggacg attacgtatc aattccagat
    16501 agggagtggt cgctatacaa aaagaattga ataaaacagg atttgttttg ttggagtccc
    16561 ttacagcgct tatgatcgct tctgtctgtg tctacttagt gagctttggc cagctgtttt
    16621 tgcttcaggc agaaaagaaa agtggggagg aactgctatt tattcgaatg atttatgaag
    16681 atatcaagac gcagcggatg tatcacaaaa gaccagagcg aagggaagaa atgatcccat
    16741 acgatatcca aattgtcgat aataatggag taatcgaaaa agtgtttgtc aatatggaga
    16801 aagaagcgat cagtattgaa aaaacaagta attccagcat ttacgctgat tgaatgtcta
    16861 attggactga tgatattgag cagtctattg ctcacattca atcttttgat tcagcaaacc
    16921 atccaagtaa gtgaattttt gcagcgtaaa gatcaaaaag agtggctaat atttttagca
    16981 caattagaag aagaactcaa gagcagtcac aatgtctctg tgaaaaatca gcaactgcac
    17041 tacacgatcg aggataaaca gtatatcatc gaaagatatc aggcaatgat acgtaaaaga
    17101 agaacttccg gcggacatca acctatgtta acaagtatca ctgagcttca attattggaa
    17161 aaagaacaca caatttcttt ttatgtacac tttgaaaatg gagaagatgg atatgccata
    17221 tggacaaaaa acgatcagta gaaaatgtta taagggctct attttatttt ctgtcttgct
    17281 tttatttctt ttatgtacgt ttttattgat ggcagcatta gaaagctacc gtttgtcaat
    17341 ggatcttaat atacgaatca aaaattatta tatagcaaaa ataatgaagc agatggcttt
    17401 atcggaacag tctacgcttg ccgaaagttc ggaaggagtt ttttactaca caactggatc
    17461 tgtaacatat cagtgggtac aacagtccct attcttagag gtggaagtct caccgtttat
    17521 ctttcggttc acagaagaag taaaaaatga tacagatact agtacagaat gatggaatgt
    17581 tcgtgaaaac gccctctttt ctgttataac actgttttta ataaaaaaat gtttgccgtt
    17641 tcacaaataa aaaacagtga aaacgattga aattttgtca attgttcgat agaattaaac
    17701 aggtgaaaaa attgttataa tatatctaga aatgaggtgc accatgttac cagaaaaaat
    17761 ggaacaaggg tttaatcaaa acctggaagc tattcagctt ttacagaatg cattgggaac
    17821 ttccttttta gaagcctatg tcgaaaatgc agaaaattta atagatgatt atcaagtacg
    17881 tgtggtggat ggagtgccga caaaagagac aacgcaacgg atcacagctc tttatgaaga
    17941 gttgaagaaa ctttctttcg agccagaaga atggcgcaga ctgtctcaat tacttttatt
    18001 gaagggcagc cagacagaac atttgcaggc gaaccatcaa ctcactcctg atagtatcgg
    18061 ttttttattt gtttttctta ttgaacaact atacacaaat aaaaaagcac cggttaagat
    18121 tctggatatt gcggcaggaa tgggcaactt gttattaaca gttcttttaa acctatcgaa
    18181 tgcggggtac caaacagaag gaattggtgt ggatattgat gatacattgt tggctgtcgc
    18241 agcttctaca agtgatttga cacaagcaaa tgttcaatac tttcatcaag acgggttgca
    18301 ggaattatta atagatcctg tcgattttgc aatcagcgat ttgccaatcg gttattatcc
    18361 gaatgacgaa aaagcaaaag agtttttaac aagtaccgaa gaaggccata gttatgcaca
    18421 tcatttattg ctagagcaat caatgaaata tgtgaagccg gatggttttg gtttgttttt
    18481 gatgccgagt ggatttttag aaacggatca aagtgaagaa atcaaaaaat ggtttaaaga
    18541 agaaggttat cttcaaggaa tgattcaatt gccagatgaa ttgttccgta ataaacaatc
    18601 gcaaaaaagt attttgatct tacagaaaaa aggaccacaa gcacaacaag taaaagaagt
    18661 cttgcttgtg aaacttgctt cattaaaaga accagagaag gtgacggaat ttttcaacga
    18721 gtttaaaaac tggaaatcat ctgctctgta atcattcaac gagaaggaga gtcatatgtc
    18781 taaaacaatt gcaatcaatg ctgggagttc aagtttgaaa tggcaattat atcaaatgcc
    18841 agaagaaacc gtagttgcga aagggatcgt cgaacgtatc ggtttacaag attctatttt
    18901 taccatcaag tacggcgata atcaaaaatt cgaacaaatc atggatatcg aaaaccacga
    18961 agtagcagta aaaatgctgt tagatcagtt gattgaactg caaattttaa gctcttatga
    19021 tgaaatcacc ggagtagggc accgtgttgt tcacggagga gaaacttatg gggattcagt
    19081 agtgatcgat gagaaagtaa tggaccgcat tgctgaatta gcagaatttg ctcctttgca
    19141 taatcctgca aacttaatgg ggatcaaagc gtttaaaaag attttacctg acattttgag
    19201 tgtggctgta ttcgatacat ctttccactc aacaatgcca aagcaaaatt atttatatag
    19261 cttaccggtg tcttattatg aagatttcaa agtaagaaaa tatggcttcc atggcacaag
    19321 tcatcgttat gtgtcggaac gtgcggcaaa attattgaac aaaccgatcg aagaactaaa
    19381 aatcatcact tgccacttag gaaatggtgt atcgatcaca gcagtcgatg gaggtaaatc
    19441 catggatact tctatgggat tcacaccatt agctggggtg acaatgggta cacgttcagg
    19501 tgatatcgat ccagctgttc tcccatattt aatggaaaaa ttagagattg atattgatga
    19561 aatgatcaat gttttgaaca agaaatctgg tctgctaggc ctaacaggat tgtctagtga
    19621 tatgcgtgat cttgaaaaga actatgaaaa agaacatatt cgtttagctt atgacatttt
    19681 cgtggaccgc atccgaaaat acatcggcgg ttatgtgaca acgatgaatg gtgttgatgc
    19741 aattgtcttt actgctggta tcggcgagaa tgacggacat gtacgtagtg aaatcatcaa
    19801 aggtatgtct tggtttggtt gtgaaatcga tccagcgttg aatgaattgc gtggtgaaga
    19861 agtagatatc tctacaaaag aatcaaaagt aagagtatta gtgatcccaa cagatgagga
    19921 actaatgatt gcccgtgatg tggagcgtct gcgcggctaa gccaaagcat tcgttaggat
    19981 aaaagatgaa acgcatgcaa gagggaattc ttgcatgtgt tttttttgcg gagaagaccg
    20041 caaaatggta atttaacttc aatttccctt cttttttaca ggatcttctt agggaatttt
    20101 gcttggaaaa gtggtcaaaa gggaaaagac tggcatttta tttattgatt ttcaggaaaa
    20161 tcccaatatt ttattttcat tcatctttat aagggacatt acatatgtaa aaagaaaaaa
    20221 catttttaga tcagcctcgt gggctgtcga ctttattctt cgctttatgt ttagctagaa
    20281 aaccgatccg aaacattcat tgatcgaata ataaaaactt gattttccac ctgtactttg
    20341 cctgaatcgt gaaagcacag gtatgaaaat caagtttttt gttgcgaaaa aacgtcctag
    20401 tcaatcagtt ggccgagcgg ctggcggctg atctgctcct gatcaataac gagtgcttct
    20461 tggaagtgtt gctgcaaaaa gtagcggtca tggctgactg ctaggagcgt tccttgatag
    20521 tcttgcagca tttcttcaat ttcttctcga gcatagctgt cgaggtgatt ggttggttca
    20581 tccaaaatca ggacgttgat tttttctaaa aagagtttca gcaacgccaa acggattttt
    20641 tcaccaccgg ataaatcttt gatccgttta cccacatcgc tttgataaaa gccacttttg
    20701 gctaattgcc gtcgagcgac ttcttcgttt ccagtcaatg tgatggcgta agccagcaaa
    20761 cggctatcgg gatcggcaaa ctgcagctgc tgcggcaaat aaccgatttg caagctacta
    20821 cctaatttga tggtgccacc gtaaggcttt tcctcaccga gtaataattt gagtaaggtt
    20881 gattttcctg caccattgtc gccgatgatg gctaaatgat ctccacgata gactgcaaaa
    20941 ctgctgtctt tgaatagtac ttgatcagcg tactgctggt gcaagttttg aatgatgaaa
    21001 acttctttgc cagattttcc accattagac aagctttgca gccgattttt cgggggaggt
    21061 ggcggtttga cgagtgtcag tttcgccagg cggcgttcca gttctttggc ttttttgaag
    21121 aaggactcat tgtctccttc atgtgcccac tgacgaaaac gacgaatcat gactttcaac
    21181 cgctggactt ctttttgctg cagttcgtaa ttttttgtca gctcagccaa gcgagcttct
    21241 ttcaagactc gaaaacggct gtagtttccg ggatactcaa tcaatgcacc ttcttccagt
    21301 tcccatgttt ttgtggtgac ttgatcgaga aattgccgat catgagaaac gaccagaacc
    21361 gatttttttg tattctgtaa atagttttcc aaccagcgaa tactgttaag atctaaatga
    21421 ttggtcggtt catcgagtaa aagtaaatcg gcatcggctg ctaaaatttt ggctaaagcg
    21481 actttaactc gttcgcctcc gctaagttct gttaaccgtg cttcctgacg gtgtggaatc
    21541 cctaagcctt gcaagatcgc tgcaatccgg tcttctaata cgtaaccgcc tagttcttca
    21601 aagcgatgct gcagctcacc gtaacgggcc agacacttct ctaagtttgt atctggttct
    21661 gtcatcaatg cttcgtagcg actcatttgc tgtttgaggt cctgtatctc agcggcagaa
    21721 tggagcaagt agtggttgac ggtcgcttcg gaaactgtaa gttcttgttc gaccgtcccg
    21781 atctttaagc cttttttgcg actgataaca ccgctgtcga caccttctct gccggtcaag
    21841 atttgtaaaa aggttgattt gccagttccg ttgataccga ctaaggcaat tttttcacca
    21901 gcttcaattt gacaggataa atcctcaaat aatggattcc cgccgattgt ttttttaata
    21961 gaaattgctt gtatgatcat gatctctctc cttgagacca ctcaaaaagg ccatggttat
    22021 ccctggcctg tgttatttaa actcagatta tcatgagaaa aataccttga gatggccatt
    22081 gattttacgt gaattcaact gttttggaca aacttgtccc gtcaacagca actgtaaaac
    22141 caattgcatg gctaaatgcg atatggtatc gttggtaatt ttcattactt gttattttag
    22201 tcatgcgcat catagtattt tccctccttc gtgtagttgt cttttccagt gtacctgaaa
    22261 gtgtcagaaa gttcaactag cgctgacatt tacttaatat ttatcgatgt gtaattctgt
    22321 cagagagctt tttttatctg actgagggta atgtctcgtg gaccacatca ttgtattctg
    22381 agctaaacca gcgttcaggc gaaatcatat ggtgtttgat aaaaaacttt gtctacatga
    22441 cttccttttg ccatttgctt aataccgttg cattaaacag ctcttctctt tggaaatctc
    22501 accaacatcg cgttcaggag tatcgttgtg gttgcaatgg caagcggtag cctttcatca
    22561 attcttgaat gatttaccga atgtagcact tgccttctcg cggtacccga acccgaaata
    22621 aaattttagt ttggcgataa aatcggtatc cgccatcgat acttcatatt ttttcgtatc
    22681 agattcatcg gaaacttcca cattgacgaa ccaataagct ttggcatgct taggtcgttt
    22741 taaaccacac cagggcgact aatcgccctg gtgttcactt tttttatttt acttgaactc
    22801 attgactgtt ttccctttat tttaaacatt ataaagaccg atgagtgctt gccgcgtctt
    22861 ttgtttttat cacggttttt tgtgcaaaaa aacctgccga tagttggcag gtcgtctacg
    22921 tgttaagctt tggtgtggtc tttagctggc aattggtttt ctaaatcagt tcggacaaca
    22981 agcacatcgc aagctgcgtt tctaataaca tattcagaaa cagaaccaat aaataaacgt
    23041 tctacagcat tcaatcctgt ggctcctaac ataatcaaat ctacttgatt atcttctggg
    23101 atttctctgg caataatttg ttttggtgag ccatattcta cgacagaggt tacattattc
    23161 aagccagctt tcttcgcatt gctttcataa tctgccaatg tttgctttgc catttcagta
    23221 gcttgttctg caagcattcc atcaaaggat gaaacggttt ggaaagaacg tgtgtcaatg
    23281 acatgtgcta atagaagttc tccgttattt cggatagcta cattgaccgc ctttttaaaa
    23341 gctaattcag cttcatcaga accatctacg gcaaccatga tttttttgta ttgttgtaac
    23401 ataagcattc actcctcaag tcaatcgtat tgtactcttt tattgtagaa cactttaggg
    23461 aaaaagagaa ttatttactg ctttggttca gcaatttttt ttgcaaatcg gatactgaag
    23521 gtggcagaaa caataattac gatcagtaaa aagaccaagg caataaagcg ttgattgaaa
    23581 aaagctgtta aaatacccat tacgcctaaa acagcatatg cagcaccgta aaattgtagg
    23641 aatccttgat ttttatcatt tttgttgatc aatacaaaaa agatatcctg tttattaaat
    23701 aaataatagc taacgaataa taatactaaa gtggcgataa tcattaaaat cctaatcatg
    23761 aacaaatcct ccaaaataag caacaaatag aaaaagcaat ttgccaagag caaattgctt
    23821 tattctttaa aagatggtaa tctccgttaa tgccgttgtt tgtcctgtag tattgatccc
    23881 gcgaattcaa gcaggtgggt cccatggtcg tagcttcgaa ctaccaaatg ataaggcatg
    23941 ttaccagcag tgacacaaga cgggtcccaa gatatcaata aaaatgttcg gtcaacacac
    24001 aaagaggaca attcgaacat cacagatttc ccacctctat agtagcatat gaatttaaaa
    24061 agagcaatga gagagctcgc agaaacagaa ccgttttctt gtctagtttt ttggaggatg
    24121 ctttttccac tcttttatac ggtaatactg ttgacccaga gcctgttcat atttccctgt
    24181 atcttttggc tgataatact gagcattctt cagtttatct ggtaaatatt gctgattgac
    24241 ccaagcctga tcaaaatgat gaggatactg ataacccacg ccacggttga gtgatttcgc
    24301 acctttgtaa tggctatctc tcaaatgatc aggaacatct ccagctttgc cctctcgaat
    24361 atcagcaagt gctgcatcta atgccatgta ggcagaattg gattttggcg acaagcaaag
    24421 atcgacgacg acgtctgcta gtgggatacg tgcctcaggc aatcccaatt tttcagcagc
    24481 taatacagcg ttcactgtac gagccgcagc agcaggatta cctaaaccta tatcttcata
    24541 accgataacc atcagacgcc ggcaaatact tgccagatca cctgcctcaa ctaaacgggc
    24601 gagataatga agtgcagcat ccacatcact tccacgaatc gatttttgaa aagccgaaat
    24661 aacgtcataa tgagcatctc catttttgtc atgggtaaga gcttttcttt ggacacattc
    24721 ttcaatgatc gacagtgtaa gatgaatcct tccttcttta tctgaaggag tcgatagtgt
    24781 agccagttcc agcccattca atgcactccg caaatcgccg ttcgttgcac gcgaaaggtg
    24841 aagaagagca tcttcgtcta actggattgc ttgttgtcca aggccgcgtt ctttatccct
    24901 taaagcatgt tcgactgcca actggatgtc ttgttctgtt aatggtttga cttcaaagat
    24961 ctgtgtacgg ctgcggatcg ctggattgat ggtaatataa ggattctcag tagtcgctcc
    25021 gatcaagatg attcggccac tttctaaatg aggaagcaga aaatcctgtt ttgttttatc
    25081 taatcggtgt acttcatcca ataagaggat cactgtacca ctcatttttg cttcttccgc
    25141 tacaacttgt agatcctttt ttgaatctgt agcggcgttt agcatgcgaa atgcataatt
    25201 agtagagccg gcgatcgcac ttgcgatact cgtttttcca gtaccaggag gtccatatag
    25261 aatcatggaa gagagcatgc gagcatcgac catgcggcgt atgatttttc cttccccgac
    25321 tagatgctgc tgaccaacga cttcatcgat cgttcgaggt ctcatgcgat aagccaatgg
    25381 ctgttgcata ggattttcct ccttcttgtt tttacgtccc ttaattatat catatttagc
    25441 aagatgccta gaaagaacag ccttctgttg ttttgttttc atagcttatc caactaatat
    25501 tgtgtatgat aaagtaggtg agaaaaatga cggataaaca aaagatagat gaattttttt
    25561 ggaataaaac gacgccagaa gtggcacggg atttattggg gatgtatttg gagcatgaca
    25621 caccagaagg aagattagct ggatatattg tagacgcgga agcataccta ggtccagaag
    25681 acgaggccgc ccatagctat ggtttaagaa gaacaccgcg tgtgcgggca atgtatgaaa
    25741 aaccaggtac gatctacctt tacacgatgc atactcatcg gattttgaac atcattactc
    25801 agccagaagg gattcctcaa ggagtaatga tacgtgcaat cgaacccgcc gcaatgattg
    25861 atcaaatgag taaaaatcgt ggcggaaaaa ctggtccaga tatcagcaac ggtccgggaa
    25921 aattagtgga agcattagca attcctcaag aactttatgg tcagtctata gcagatagtt
    25981 cgttacgctt agtttttgag aaaaaaaaga caccaaaaaa gatcaatgct ttgcctagaa
    26041 tcggtatccc aaacaaaggt gtatggacag aaaagccgtt gcgttttgtt gtgtcgggaa
    26101 atccttatat ctctttacaa agaaaaaacc aaatcgagaa agattggggt tggaggaaag
    26161 aaaatgaaaa agaaggatct attaacatat ttagatgaaa taattgaaaa acaagtgaca
    26221 gactatgatg tagctttaga ttgggataca aaaaatcata cgatcgagat cgttgttcgc
    26281 ttgtttgcag aaaataaagc acaatttgag attgatgatg cagaagggat cgtttcgcaa
    26341 gaaccaatta tcgaatttga agacggcgta cttcttttta atcctcagaa atctgttttt
    26401 gatgaacgca attatctagc agtaatccct tatgaaggaa aaaaagggtt ggcaaaatca
    26461 gtagctgatt ctttagtgga atatctaaat gaagtattag ctcaagggca aagcgatttg
    26521 cttgattttt tggatgaaga cgatgacgaa gctgtattcg agcttcactg ggataatcaa
    26581 caactagcag aattagtaga agtaaaacag caaaatgaag cagatactta tttaccgtac
    26641 ccaagttatt aaggagtgac agatatgaaa tggaatgaag taaaagtaga aactgaaagt
    26701 gaagcagtcg aagcagttgc taatattttg atggaggcag gggcgagtgg tgtcgcgatt
    26761 gaagattctt tagatgttga acattttcag tcggatcaat atggtgagat tttagataaa
    26821 aatgatttta catcgctgaa agaaggcgca ctagtcatgg cttattttcc ggaaacgact
    26881 ttcttaccgg aaatcttgcc ttttatcaaa gatcgtatca cacaattacc tgagtttggt
    26941 ctagctattg gaaaaaataa agtaacagtt agtgaagtag aggaaagcaa ctgggcaaca
    27001 gcctggaaga aatactatca tccggtgcgt attacgcgaa tgctgacggt tgcgccaagc
    27061 tgggaaaact accagacaga agatcctcta gaaaaaatta tcacactaga tcctggtatg
    27121 gcatttggca caggcactca tcccacgact tccttgacat tgacagcact agaaacagtc
    27181 ttgcgtggtg gtgaaacatt gctagatgtg ggaactgggt cgggcgtgct aagtattgca
    27241 gcaaaatatc ttggtgcaaa agatgtctat gcctttgatt tagacgaagt agccgttcgt
    27301 tcggcgaaag aaaatatgga tatgaatgaa atagccaaag atgtccatgt atcagctaac
    27361 gatcttttga caggaatcga gattgaaagt gatgtaatcg ttgcgaacat tttagcagat
    27421 atcatcttat tgatgatccc agatgcttgg cgtttactga agcaaacagg cacgctgatc
    27481 gtttcaggaa tcattgaaga gaagaagcaa atggttctgg atgccatgtt agaacaaggg
    27541 tttatcgtgg atcaaatttt ccagcaaaaa gactggtatg caattatttt gaaaaaacca
    27601 gaggtggaat agatgcagcg gtatttttta aaagaatcat atgaatcaaa agactatttt
    27661 gttttagaag gggaaaacta tcaccacatt gtacgggtta tgaggatgga acccgaggat
    27721 gaagtttttt tggcattcaa tgatcaaata gccattgttg cagaaatcac ggagattact
    27781 gaagaggctg tttatctgaa agaaattaaa aaagaagaaa atcaaaagga actgccaagt
    27841 tcgattacca tagcgagtgg ctatcctaaa ggggaaaagc tggattggat cgttcagaaa
    27901 tccactgaat taggagcgca agcttttctt ggtttcccgg catcagcctc tgtcgttaaa
    27961 tgggatgcaa aaaaacgtat gaaacgacaa caacggcttg aaaagattgc tcaagaggca
    28021 gcggaacaat cccatcggca gatcgtgcca tcagtagagt tattggaaac gaaacaagat
    28081 ttatttgagc ggctagatga ttatgacgtg gtcttggttg cttatgagga atcagcaaag
    28141 caaggcgaaa aatcaaatgc agccaaaatt cttagtgaaa caaaaccaga tagtcgaatc
    28201 ttagctgtct ttggaccaga aggtggatta tcccgcgatg aagtcgatta ttttgtagaa
    28261 cacaaaggga tactttgtgg attaggacca agaatccttc gtacagaaac agcacctctt
    28321 tatttattaa gtgctgctag ctatcaatgg gaattaatga atccttcttt cagctaacgt
    28381 tcttcattaa taaaagagta tcgacagaaa gaattgaaaa aatagtcaac aatttgtata
    28441 atagaaacaa ttatttatac aatggatacg aaaaatcgtt tgaaaaagct tttaaaaagc
    28501 gaacatttcc gtaaaaaaac gtataactgc acggattttg ggacaattat caaacagata
    28561 tttgtcccga ttcccgtttt accgaaaaaa gaaaggggga tcgattcctg tgacaaaaga
    28621 agaaatttta acgggacccg gtgtcataaa gctcgttagt caatacatgg gtcccgaaca
    28681 tgtagcattt gttgagaaag catgcgaata cgcgactgct gcacatgacg gacagtttag
    28741 aaaatcaggc gaaccctaca ttattcatcc tatccaagtc gcaggtatat tagcagattt
    28801 aaaaatggat ccccatacag tggctacagg cttcttacat gatgttgttg aagatacaga
    28861 aatcacttta gaagatctga gagaagaatt tggcgatgac gttgctatgt tagtggacgg
    28921 cgtaaccaaa ttagggaaaa taaaatataa atcccacgaa gagcagctag cagaaaacca
    28981 ccgaaagatg ctgctagcaa tggctcaaga tttacgagtt atcatggtca aattagctga
    29041 tagactacat aacatgcgta cgttgaagca cctgcgagaa gataagcaaa gaaggatcgc
    29101 tcaggaaact ttagaaatct atgcgcctct tgcacatcgt ctagggatca gccggatcaa
    29161 atgggaatta gaagatacag cacttcgtta tctaaatcca aaacagtatt accgtatcgt
    29221 ccacttgatg cagacgaaga gagaagaacg tgaaaaatac gtaagtggta ctgttgaaga
    29281 tattcgaata gcgacagaag agctggggat ttttgcagaa atctatggac ggccaaaaca
    29341 catttattca atctatcgta aaatgaaaga tcagaaaaag cagttcaacg aaatttatga
    29401 cttgctagct attcgagtga tcgtagattc aatcaaggat tgttatgctg tattaggagc
    29461 aatccacaca aaatggaaac caatgcccgg cagatttaag gattatattg ccatgccaaa
    29521 agctaatatg taccaatctt tgcatactac cgtgatcggt ccggcaggaa atccggtaga
    29581 aattcaaatc cgaacacagg aaatgcatga aatcgctgaa ttcggggttg ctgcacactg
    29641 ggcctataaa gaaggaaaaa atgaaaaagt agaaccagat ggtatgacga aacaattaag
    29701 ctggttccat gagatactcg aacttcaaga cgaaagctat gatgcttctg aatttatgga
    29761 aggcgtaaaa ggagatatct ttagtgataa agtctacgtc ttcacaccaa aaggagacgt
    29821 tactgagtta ccaaaaggat ccggaccatt ggactttgca tacagtatcc atacagatat
    29881 cggtaacaaa accactggtg caaaagtaaa tggcaaaatg gtgcagcttg attacaaatt
    29941 gaaaaacgga gatatcattg agatcatgac ttctccaaat tcatttggcc caagtcgcga
    30001 ctggttgaaa ttagttgcta ctagcaaagc aagaaataag atcaaacgtt tcttcaaagc
    30061 ccaagatcga gaagaaaatg tgatcaaagg ccacgaatcc gtggtcaaat gtattacaga
    30121 tctaggattt acgcctaaag atattttgac gaagaacaaa ctgcaagaag cactcgatcg
    30181 ttttaattat caaacagaag atgatctcta tgcagctgta gggtatggag aagttagccc
    30241 cttgacgatg gccaatcgtc tgactgaaaa agaacgtaaa gaacaaaaaa tcgagcagca
    30301 aaagcaagaa gcagaagaaa tcatgaatca gccgaaaaaa gaacctgaca aaatgaaagt
    30361 acgtcatgaa ggtggcgttg tcattcaagg ggtagaaaac ttactaattc gtatcagtcg
    30421 ctgctgtaat ccgattcctg gtgatgatat cgttggttat atcactaaag gcagagggat
    30481 atccattcat cgtcgagatt gtccgaatgt tcagcctgac aaaccaaatg tagcagaacg
    30541 tttgattgaa gtcgaatggg aagatacatc gaatacacga aaagagtatg atgcagattt
    30601 ggaaatttac ggctataatc gttcaggctt attgaatgat gtacttcaaa cagtcaatgc
    30661 gctaacgaaa aatctcaaca gcgttgaagc acggacgaat aaagataaaa tggcgacgat
    30721 ccatttgacg gttggtatcc agaatttatc ccacctaaag agtatcgtgg ataaaatcaa
    30781 agcagtacct gatgtctaca gtgtacgccg gacgaatgga taggaggaca gatatgagag
    30841 cagttgttca acgggtaagt aaagctgctg tgtcagtcga tcagcaagaa attggaaaaa
    30901 ttggctacgg cctacttgtt ttattaggca ttcatgaaac cgatacgcaa aaagatgtgg
    30961 actatctggt aaaaaaaatt gcacaaatgc gtatttttga agatgaacaa ggaaaaatga
    31021 atattagtgt agaagatgtg ggaggacaaa ttttaagtat ctctcaattc acactgtttg
    31081 cggatacgaa aaaaggaaat cgaccaagct ttgtggaagc cgcacgacca gaaacagcta
    31141 ttcctttata cgaatcattc aatgaaggaa tcagaagtcg cggcatcaca gtcgctaccg
    31201 gacaattcgg agcagatatg tcggtttctc tcgtcaatga tggacctgta acgatcatta
    31261 ttgattctaa aaacaaataa agtaatctgg ttttcactag taaaaactat gaaacacgtc
    31321 gcttaagtta gactgataaa ctctaactta agtggctttt ttgtctgcaa aaagcgcttc
    31381 ttttgtcagc agtcggaaaa aaagttaagc ttaaattata caagttattt tttataggag
    31441 gttgctgaag atgaaagaag taccagtagt agatatcaaa atcacagatt taaaaaaatt
    31501 gtatcaaaaa ggatacaaca tgttggagga gttacgccat gaagcggacg ctcccgtcgt
    31561 caaagcaaag attttcaata aagaagctat cacgatctac ggatcatcag cagcaaaagt
    31621 attttatgat ccaaggaatt tcaaacgaaa aggtgctatg ccaaaattag tattgaagac
    31681 actttttggt caaggtggag tacagacttt ggatggagct gctcatcacc atcggaaaaa
    31741 tatttttatg gatctaatga caccggaaag aatggaagat tatcatcgta tcttagataa
    31801 gaatctgaca caagcacttg aagcacagca tggtcaattt gaactatttg atttaagtaa
    31861 gatggttttc tttacatcta tttgcgagtg ggcaggtatc aatttatcag cgatttctaa
    31921 agatgaggtc gaaaaattag cagaatatca aatctctatg atcagcggaa cgtttacttc
    31981 tccgattgat cacataaaag gtgtcgagaa tcgcaaaaaa tcagaaaaat gggcgcaagg
    32041 cttgattgaa gaagctcgac aaaatcctgt ggctggaaaa gaaaatgtgg cattatatgc
    32101 ttttgccaat gccacagatt tagatggtca gcttttacct ctggaagtgg cagctgttga
    32161 attattgaac atcatccgtc caacggttgc tctaactgtg tgggcggcat tgatgggaca
    32221 tgcacttttc agtagaccag atttgtatca gcaattaaaa aatgactttt cgacgttaca
    32281 agatccgttt attcaagaaa tgagacgcta ttatcctttc ttcccaatgc tacctgcgat
    32341 ttcgctgaaa gaagtagaag tagatggtta tcgtatacca gaaggcagtt gggttatttt
    32401 agatttatat ggaacagacc atgatgaacg aacagttgaa gcgccagatt cctttatgat
    32461 caaacggtat gtagggaaag caaaagatat ttcctataaa gaagaatatg agatgattgc
    32521 acaaggcggg ggaaattttc gacaaatgca tcgctgtgca ggagaatgga tcactcttca
    32581 tagtctacgt gtgttttccg atcagctagt aaataagttt gagttctctg tacctgaaca
    32641 agattggacg attccattca atcagtttcc gacttatccg aatagccgag cgctacttta
    32701 caagaattag attagcataa acttatcgaa aaaaaggaag atcaaacagt gctgatcttc
    32761 cttttttcat attactataa attgataagg tcaattgatc aaaatccacg aaatgcttca
    32821 tcaatggttt gataatcttc attggataaa tgcaaatcta aagcttggac attgtcagat
    32881 acttgctctg gacgcttagc tccaggtata actacagaca ctcgtggatt cttcatgtac
    32941 caagctaaaa caagttgcgc aggagtggct tggtatcttt tagcaatggg gcgaagtaca
    33001 tcgacagcgg ttaaaatttc tctgaaacgt tctccttgga aatctggatt tctttttcga
    33061 ggatctcctt caccaaattg tttttcctca ccaagttcat attttcctgt cagcaaaccg
    33121 gaagcaagag gaaaataggg aacaaaactg attttgtttt tttcaagata agggaataat
    33181 tctttttcag cctgccgatg gatcaaactg tatttatctt ctactacatc gacatatcca
    33241 tctgcattcg cttctttcaa ttgttctaac gtgaagtttg acacaccgac tgctcggatt
    33301 tttcctgctt cttttaattc gtgcaatgta gcaactgatt cattttttgg tgtgctttca
    33361 tccggaaagt ggatataaaa aatgtcgatg taatcagttt gcagacgttt tagtgcatct
    33421 tccaccgatt gtttgagaaa ctcaggagaa ttatcaaatg ttcgcccttt atttggtaca
    33481 tgagcagctt ttgtagcgat gacgacacgt gagcgatcat attctttttc cttcagtacc
    33541 tcgccaatca gttcttcgga acggccgttt ccgtaagcat aagcggtatc gatcaaattg
    33601 atcccgctat tcaaagctgt acgaactact tgttttcctg tctcatcttc caaaccgtca
    33661 aaaagattat gtcctccaac ggcatttgct cctaatccaa gctgttctgc gtagacttgt
    33721 gaatgtccga ttcttatttc tgccatagct gattcctcct ttttgtctag tctaaaacaa
    33781 aataccaaaa agctgaacta aaacgttttt gtgaggggaa atagtcagat atctcttgac
    33841 tttgagactg gtttttagta ggttataagt aatatcgaat gtcaatgaaa gagcgagtaa
    33901 gtttttgaaa ctttacaaga gaggatcatc gaggctgaaa atgatctaaa gtttcattag
    33961 cctaaagaca ctctggagat ggacgagtga aaagccgtcc cgcgtacgag cgttattcgt
    34021 aagaggaaag agaaatcttt caaaattagg tggtaccgtg tatgaatttc attcaccctt
    34081 gttcatgatg aacaagggtg atttttttat ttacatagct aagaaaggga gagaaaacta
    34141 tgagtttcca aagaccaaaa ggaacaaatg atattttgcc aggcgaatca gaaaaatggc
    34201 agtttgtcga agaaacagca cgtttattat tcagagatta tcagtataat gaaatgcgta
    34261 caccgatttt tgaacactat gaagtgatat cccgaagtgt aggggataca acggatatcg
    34321 tttcaaaaga gatgtatgat ttttatgaca aaggggaacg ccatgtgacg cttcgaccag
    34381 aaggtacagc accaatcgtt cgttcttttg ttgagcataa attgttcggc ccagagtatg
    34441 cgaaaccgtt caaaactttt tatatgggac caatgtttcg ctacgaacgc cctcaaaaag
    34501 gacggttacg tcaattccat caaatcggag tagaagcatt tggatcagaa aaccctgcaa
    34561 ctgatgtgga gagcatggtg atggcacttg atttcttcaa acagttgggg atcacgcaaa
    34621 tccggctagt catcaattca ttaggtgata aagaaacgcg tcaagcctat cgtcaagcat
    34681 tgatcgacta tcttttacct tttgaatcag agctgagtga agactctaaa cgccgccttc
    34741 atgaaaatcc attacgcgta ttggacagta aagacaaacg agatcaaaaa tttgtggcag
    34801 aagctccatc tatcttagat tatctaagcg agcctgctca aaaacatttt gataccgttg
    34861 tttccatgct ggatgcattg gctgttcctt atgaaatcga cagtaatatg gttcgcggac
    34921 tagattatta cacacatacg atttttgaaa tcatgagtga cgcaccaaaa atgggggcac
    34981 aagcaacgat ttgcgcaggc ggacgttatg acaatctagt ggaagaacta ggtggtcctt
    35041 caacacctgg cttcggattt gcaatgggta tcgagcgatt actcttgact atggaggcag
    35101 aggaagtagt tatccctgca tttaatgagt tggatgctta cgtggtcgca ctcggagacg
    35161 aaacaaatat cgaagcattg aaagtggtcc aagcgattcg aaactttggt ttttcagctg
    35221 accgcgactt catgaaccgt aaagcaaaag cgcaatttaa gacagcagat aaagcgaatg
    35281 ccaaattagt attggtgatc ggtgaagatg agcttgctag tcaaacgatt aatgtcaaag
    35341 caatggcaag ccgaaaagaa aaaagttttc cattagaaga gatatatgaa cattttgatg
    35401 aagtctatga tgaaatgact ttattcgagt aggaggaaaa aaataaatgg cacaaagaac
    35461 gatctattgc ggattagttt ccgaacaaca attagaacaa acagttacat taaaaggatg
    35521 ggtacaaaaa agacgagacc ttgggggagt aatctttatc gacctacgtg atcgtgaagg
    35581 aatcgttcaa atcgtcttta atcctgaaat caacaaagaa gcatgggaaa tcgcggataa
    35641 atgtcgcagt gaatacgtga tcgaagtgac tggggaagtt agaagacgcg gagaaaatgc
    35701 agtaaatcct aaaatggcca ctggtgaatt cgaagtgatt gcaagtgaaa tcgtgatttt
    35761 gaatcaagca aaaaccccgc catttcaaat tgaagatgat caagcaatca gtgacgaaat
    35821 acgtttgaaa tatcgttatt tggatctgcg tcgtccaaaa atgactaaaa acatcaaatt
    35881 aagaaatgcg acaacaaaag cgattcgtca ttatttagat gataatgact ttctcgatat
    35941 cgaaacacct tacctaggga aatctacacc agaaggcgca agagactacc tagttccttc
    36001 acgtgtccat gctggacatt tctatgcgtt gccgcaatct cctcaattgt ttaaacaatt
    36061 gctgatgaat gctggattcg accgttatta tcaaatcgtt cgttgtttcc gcgatgaaga
    36121 tttacgtgga gaccgtcagc ctgaatttac gcaagtagat attgaaacaa cgttcttaac
    36181 agcagaagaa atccaaactt acacagaggg attgattgcg aaggtaatga aagaagttcg
    36241 cggtatcgaa gtcacattgc catttcctcg tatgacctat gatgaagcaa tggctcgcta
    36301 cggcagcgac aaaccggata cacgttttga tatggaattg atcgatctaa gcgatacagt
    36361 caaagaagta gaattcaaag tcttccaaat ggctcttgaa aacggcggtg tcgtgaaagc
    36421 attgaatgct aaaggcgctg cagatcgcta ctcacgaaaa gacatggatc agttaggtca
    36481 atatgtagga caattcggag ctaaggggct tgcatggctg aaagtagaag aagacggatt
    36541 gaaaggtcca attgctaaat tcatgggaga agcaacagaa gcaatcatta aagcaacaga
    36601 tgcaaaacca ggtgacttgc tgatgtttgg cgcagataaa agtgaaatcg tcgctgctgc
    36661 attaggtgct atccggacac gtttaggaaa agaattagga ctaattgatg aatcgaaatt
    36721 caatttctta tgggtaactg attggccaca atttgaattt tcagaagaag aaggtcgata
    36781 tgtctctgct caccatccat tcacgatgcc aaaagaagaa gatatcccgt tattggctga
    36841 agaccctgca aaagtctatg cagaagctta tgatatcgtc ttgaacggtt atgaattagg
    36901 cggaggttct atccgtattc atactcgtga gcttcaagaa aaagtactag aaactctagg
    36961 ctttacaaaa gaacaaatgg aagaacaatt tggtttcttg ttaacagctt tagattacgg
    37021 attccctcca catggcggta ttgcattagg attggaccgt tttgcaatgt tattagccgg
    37081 agaagataat attcgtgaag tcattgcctt tcctaaaaac ggaaaagcag cagatgtgat
    37141 gagtgatgca ccaagtatgg tttcgccttt acaattgttc gaattgaata ttgatgtaac
    37201 gaatatagaa gaatagccga taaaaaggta aaaaggattt gtcgaatacg cttcttttga
    37261 caaccttgat ttaattgaaa aacactttat aatgaagcca taacatataa agcggggctt
    37321 ttccatgaaa aaaacattcg aaaattgggc ttatcatgat tacacgacca agctttcggt
    37381 atctatcgtt tatgcgttga tcgcatcagt cgcattgaat ttcttttatc agccaggaca
    37441 tatttattca agtggtatta ctggtctagc tcagattttg acgactttgt caaaatcact
    37501 gataggattc gaagtaccgg tatcaacaac tttgtattta ctgaatatac ctttgtttgt
    37561 attggcgtgg ttaaaaatcg ggaagaagtt tacaattttc acttttatca cagtcacttt
    37621 gacctccctt tgtatccata ttttaccgga aacagtccta tctaccgatc caatcatctg
    37681 tgcgttgttt gggggggctg tgatgggact aggtattggg ctagcgttga gaaacggcct
    37741 atcatcgggc ggtctagata tcgtgagtat cacgattcgt aaaaaaacag gaaagtcgat
    37801 tggttctatt tcgatctact tcaatgcatt gatcgttttt gttgccggaa ttctatttgg
    37861 ctggcaatat atgttttaca gtacgttgtc tattttcgtc agtggaaaag taactgatgt
    37921 cgtttatact aaacaaaaga agatgcaggt aatgatcgta acgaaacatc cagaaaaagt
    37981 agtaaatgaa atccaaaact gtatgcgtag agggatcacg atcatcaatg aagcagaagg
    38041 tgcttataag catgataagc agacagtatt gatgacgatc gttacacgat acgaactgcc
    38101 tctacttaga gaagcaatga aagcttctga tccacaagct tttgtaagta ttgcagaaaa
    38161 cgtccagata cttggtcgtt tctatgagga tggcatttag atcgagtttg acaaaaattc
    38221 atgaaatact gctgtagaca gacgttcgtt tgtctgcagt ttttttctac catagtagaa
    38281 tcagcaaaga aaaactgctt ttttatttga aattttctta aagttgaaaa aaagcatgtt
    38341 tattttttta aatttatggg atgatagaaa aaaatagtag agaaaggaca cgattctact
    38401 tgctattttc acttaatacc cgtatattac gaatgaaaaa agtttatgaa aagttggaat
    38461 attgaatgga aaaacaaaaa aggttaaaaa acagccgcta catcactggg tttgatgggc
    38521 tccgttcatt agctgtggtg ggtgttatct tctatcacct tctgccaact agtatgaaag
    38581 gcggctattt gggcgttccg atttttttcg tcgtatctgg ttatttgatc acggatctgc
    38641 tgcggcagga atgggaacaa aatggaaaaa tcaatatttg gcaattttat gtcagaagaa
    38701 tgaagagact ctatccggca cttgttttta tgcttgtgac agcttcggct tatatcactt
    38761 tgtttcagcg agggctgtta aacaatcttc gaggagttgt ggtcagcagc ttactgtatg
    38821 tcaacaactg gtggcaaatc agtaacggtt tatcttattt cgatcgattt gctaatgagt
    38881 caccgtttac gcatatctgg tctttagcag tagaaggtca aaactatttg gtttggccga
    38941 tcttgtttgt attgttgatg gtatttgttc gtaaaagaaa atggatcttt tatactgtgt
    39001 taggtacatc cttcctctcc gccatcttga tgatgatctt gtatacacca ggaggcgatc
    39061 caacccgtgt ttattacggt accgacactc gtctgttttc tatatggttg ggaagtgcgc
    39121 ttgcgtttgt ttggccaagt acgcgtttaa agaaaaacat cccgaaacaa gcgaaaaata
    39181 ttctgaatat cgctggagga atctcgcttt tggcactgat tctttgcttc ttctttttag
    39241 atgatcatta caatttcatc tattacggag gaatgctcct agtgagtctg ttatgcgtag
    39301 tgctagttgc agtgacagca caccccggag caagtttgaa tcgatggctg acaaatccag
    39361 tatttacttg gattggcaaa cgaagctatg gcatttatct gtatcagttt ccagttatga
    39421 ttttttatga agcaaaggtg actgatattg ccgatcatgt tttgttgcat actttagtgg
    39481 aaatcacatt gattctaatc atcagtgaac tttcttatcg atatgtggag cgtccgctag
    39541 cacgttttga ttatggtcgt acattccaag tgatgaaagg atggttcagc aaaccgatca
    39601 tcagtaagag caaaccatgg gttgttccag gcacattact tgtagcaatt gcactcgttg
    39661 gtttcgttac ggcaccgaaa aacgctgtaa cagccgatca aaaacaactg caggcaaaaa
    39721 tcgctgaaag taaaaaatta gcagaagaaa ccagaaacaa ttcagaaaac accactagtt
    39781 cggttgacca agcgatcctt gataagtacg agttgtccaa ggcacaaggg aataaggcac
    39841 aaaaattaga actaacggca tttggtgatt cagttatgtt ggatgctgca acggatctac
    39901 aagaacttta tccaaaagta gtggtagatg gagatgtcgg acgacaatta tatgccagtg
    39961 taccgtacat tgaaaaatta aaggaacaag atttgttgaa agacactgtt ctgattggac
    40021 taggaacgaa tggctcattc tcggaagctc agtttgatag tgtgatggat gcaatcggtg
    40081 atcgaaaagt atactgggtc aatgtccgag taccgacgaa gcgctggcaa aatgacgtga
    40141 atgcgatgct tgaacagatg acgaaaaaat acgacaatat gacgctgatt gattggtaca
    40201 gctacagtaa tgaccatagt gactggtttt atgatgatca agtccatcca aatcctgaag
    40261 ggatgacaca ttacattcac ttagtcagcg aagccttgct aggaggaagt tcaagtacga
    40321 acagcagtga gacaaacgtg acagaatgat agctacaaaa aacttcaggc aaaaacattt
    40381 gtttttgcct gaagtttttt tatatttacc gtgtttttaa cattcatata gattcaggaa
    40441 gcaaaacggt tgagtgtgtc tgtaaataac gttctttttg ttttcgggtg agttttttga
    40501 atgcagcttc tgcttttgtt gcttcgcttc ttgaagaaaa tacttctgca tggatcatct
    40561 taacaggtct tcttttttga agacgagtat atttagcacc agtaccattg ttatgttcct
    40621 ctaatcgtct agaaagatcg gttgtatatc caccataaaa tgtctgatct ttacagaata
    40681 atacgtaaaa ataatgttca tttgccatag agcatctcac gaatctctgc agtgtattct
    40741 ccatccatat tgtaagtgat caatggtgga gcgactttga atccgtctaa tttgccttct
    40801 ttgattcctt caactaacaa aatatttgcc tcttttccag gttttgggta aacaaattgg
    40861 atccttttag gtgcaattcg atagtcttcc atgacctgaa tgatttctaa gaaccgatca
    40921 ggacgatgga ccatagtaaa gcgtccattt gtttttagta gcttacttga aatatcgatc
    40981 acttcttcta acgtcgtatg aatctcatga cgggcgattg ccaggtgttt attagggttc
    41041 gttttatttg ttggcagccc tttgaaataa ggtggattac agacgactaa gtcacaagaa
    41101 ttatgtcgaa cgacagataa gctgtctttc agatcgatgg tgtggacagt catttgttca
    41161 tttaaatggt taagcgcgat actacgtctt gccatgtctg ctagacgagg ttgaagttcg
    41221 atagcgtcga tagccgcctg ggttcgttta cttaaaaaaa gtccaactgc gccatttcct
    41281 gcacaaaggt caacaatctt ccctttttta ggtacacggg aaaagtgagc aagcagcaca
    41341 gcatctaaag aaaaagaaaa cactttggaa ctttggataa tcttgatatc ttctgcgtat
    41401 aattggtcga ttcgttcgtc ttcgtgaagc atggattccc tccaaaatga aaaaaatagt
    41461 cgtctgtatt atactatttt tattaaaaag aaccaaggtg gcttgtcaaa cctctatttt
    41521 ttatgcatac tatgaccata agaagggaaa ggaagagact atgttttatc gatttatgcg
    41581 cggggtagtt cgagtactat tagccttagt taatggaaat gcccgctatg agaataaaga
    41641 agttttaccg caagatgaga attacatact agttgctccc catcgtactt ggtgggaccc
    41701 attatatctg gcggtagctg cagcacccaa ggaattcagc tttatggcaa aagaagaact
    41761 gttcaaaaat ccagttctgc gatttatatt aactcgatcc aatgcttttc cagttaaaag
    41821 agaaaatcca ggaccaagcg tcattaaaac acctgtaaag attttgaaat cgacaaattt
    41881 gagtttgatc atgtttccca gtgggacaag acatgctaca gaacttaaag gcggaatggc
    41941 attgatttcc agaatgtcta aagcgaaaat cgtgccagct gtatatcaag gtccgttgac
    42001 acttggggat ctgttcaagc gtcagagagt gacagtgcgt ttcggcgaac caatcgactt
    42061 atcagatatc aagaaaacgg ataaagaagg tatggcggag atcgaacgac gaacacaagc
    42121 agcttttgac aaattggaca aagaagtgaa ccctgatttc aaatatgaag tcaaaaaaaa
    42181 ataaaatgat aagtttatgc gtgggcggtc ttttgaatct actgtcctgt tcagttcaga
    42241 ctttttcaat gaaaacgagg gagagacgtc aagtctgccc tctttttgcg ttccaatatg
    42301 taaaatagaa gacaggtgtc atgtaatgga tcaaagtgtt ataataatta gaaggacatt
    42361 ttttgaggtg attgaatgcg ttttttacat acagccgatt ggcatatcgg aaaaaaacta
    42421 caaggttatg acttgattga agaccagcgt catgtactat cttctatact agatatcgcg
    42481 aaagaagaaa aagtagaggc aatcgtgatt gccggagact tatatgatag gagtgtccca
    42541 gctgttgatg ccgtagaatt atacaatgaa ttgatggtcg attggaattt aaaggaaaag
    42601 atcccgattt ttgctatatc aggaaatcac gatagcagta cgagactttc agcgggtacg
    42661 ccatggttca gttattcgaa ctattttttg cgaacacagc tagcagaagc atttgaacca
    42721 gtcgagttta aaaacgtaca atttttcttt cttccttact ttgaaccaat tgcagcgaga
    42781 ttatattttg aagatgacaa tatccgaacg atcaagcaag cggtagccaa ggtgatagat
    42841 aaaatgcagg agctatttga ttcagaaaaa aaacaagtat tgattagcca tttttttgta
    42901 atgggaagtg taaaatctga ttcggaaacg aaaatcgaag taggcgggtt ggattcgatc
    42961 cctggtgaac tacttacacc gtttgattat gtagcactag gacatttgca taatcaagct
    43021 gctttgagac aggataatgc tcgctatagc ggttccccat tgaaattctc tttatctgag
    43081 atcaaccaaa aaaaaggcgt atggatcgtt gacctgacaa caggcctgga gttgaatttt
    43141 agggagatcg aacccctgca tgatattgaa gaaataacag cgagtttcaa agaattgctg
    43201 gatcctgcct tttatcagtc cgtcaatcgg gagaattaca tctatatcta tctcactgat
    43261 agaacgatca tcccgaatat gatgaaccag cttcggcaaa tatatcctcg tattttgggg
    43321 attgaacggg caaacggtcg agcagaacaa acaaagcgca aacgaaaagt actagaaatg
    43381 aaagatcctc aaaaattagc agaagcattt tttagtgaaa tgacggaaga gcagctaact
    43441 gcaaaccaag aaaaatggct cggagaaacg ttgcaagaaa tcatggaaat ggaatgatca
    43501 agaatgaaac cgaaaaaatt acaacttaaa aattttggtc cttttatcaa tgagaccgta
    43561 gatttttcac gtttgacaga agcaccgctt tttttgatca gcgggaagac aggagctggc
    43621 aaaacgacga tttttgatgg gatcaccttc gcactttttg gtgaaacttc cggaagactt
    43681 cgctctggaa aagagatgcg ttctttgttt gctacaccag acgaagaaac aagcgtgact
    43741 ttttcttttg aacatcagca gatgagctat gaaatcgaac gaaaaccaga acaagtttta
    43801 gcaaaacgaa aaggaaacgg aacaaaaaaa caggcagcca aagtaacgtt gaccattttt
    43861 gatgggaaag gaaaagaaat aaaacaaatc acaaaacgta cagaagcaga tcagttgatc
    43921 agagaactga tgaatctcga tgcgaaacag ttttctcaaa tcgttttact accccaagga
    43981 gaattccgta attttttggt ttcatcaagc agtgataaag agactgtttt acgtcattta
    44041 ttcggtactc aatttttcca acagttcaat gagcgattaa aagaaaaagc aaaacaacag
    44101 caacaaaaat tggatcattt agagcaagag ctgcatcttc tgcaaaaaag gtttgtttta
    44161 gtcaaagaag aggaaccagc agcagggttt gaagccgttt tagcccaatg gacaaaccat
    44221 caggcaatac tcgaaaaaca aatcacggaa gaaaaagaag ctctaacgga acttcaggaa
    44281 aaacaaaagc aactagaaaa ttcctactat cgttttgaaa gcttgaaaaa aagttatgaa
    44341 gaaaaaacga tattaataaa caagcaaaag gaattagctg ctcaaaaaga cgaaatagag
    44401 gaaaagaaac gatggattgg gtattatgaa tttacgcaac gattagtcga accaatccag
    44461 cgcctacaag aaataaaagc tgaaaaaata gaactgtcgc aaaaaagtag tgagcaaaca
    44521 aagaaactag cgatgactac gcagaattat gaagagtggc aaaaaaatga agcaaaccgc
    44581 gtacgccgac aaacaaaaat caaagaagct gctcaaaaac tgcaaaacaa acagatgatg
    44641 gtgccaattg tcgaatcctt acgtagtaaa aaacaagacg cagaacaatt aacaatttca
    44701 ttggataaag aagaattgaa tgccgagaag ctgtatcaaa atctcgctat ctatcaggaa
    44761 agaactcgaa ttcttcaaga aaatttactg gatcaggaaa aactgcaaga agatcgtctt
    44821 gcttttggac agttaaaata tctagatgaa aagcagcaag aaatagaaaa acaaaaagca
    44881 aaagacactg ggtcgctcgc acagataaga gaagaactca aaaaagcaac tgaagaaata
    44941 acaaaaaata gtcagctatt gaaagaacag acagaacaag cagaacagct gaaaagccaa
    45001 tgggcaaagc agcaaattgc tcgtcttcag ctttttttgc gtccagggga gccatgtctt
    45061 gtttgtggat caacggaaca ccccatacaa caattaaaac acgaacagcc aaataaggaa
    45121 gatatcttaa aagtagaaca acaactggca gaagctgagt ctgctgtaga aagaactcag
    45181 caaatcattg ccaaaagtga agcacatgaa aataatcttc aacaacaatt atcagattta
    45241 gaacaaaaaa tcatggcaac gaatatacaa ttggctgaac aagaagaaca cttgcaacag
    45301 gctttgaaaa aggcatttcc tgagataaca gaacaaaaaa caaaaacagc tcttgtagta
    45361 atcgaacaat ctttagatag acgaaaaagc aagatggcca atgcaagaat agagctggaa
    45421 gaaataagac aacaagcaga aaagctcgaa caacaattag ctgtctacaa acagcagcag
    45481 acagaaaaaa ataatcagct ccagcaactg caaggagaaa tcaaaagttt agaacaacaa
    45541 ttgcaagata cggatagtaa ctgtttagaa gaggagatac gacgacttga aaaacagtta
    45601 gaagaagact cgaatcaact agctgttgag cagaaagcag gagtgcaatt gttgcaagat
    45661 cttcatacgc ttcggacaca gcttgatctt caacatgaac aaatagaaaa aatagatgaa
    45721 aaaatagaaa aggaacaaga aagaatagct aaaaagttag aaagccagtc gtatttttca
    45781 acaattgaag aaatctgtgc atttgcacaa cagcaagcac aatataaaga aaaccaacgt
    45841 acagttactt cttatcatga agagcaatta gtgacagctg accggctgcg tcaattagaa
    45901 aatatccagc taactgagac attcccagat acagaagaga tcagccaaca gttagaagaa
    45961 ataagacgta tgatcgaaat aaagcaagaa aagatatacg gtttacaaga acaaaaaatt
    46021 agtaatcaaa aaatctacga tgaatgtctt tcgatttatc acacaagcca gacgaaatta
    46081 gatgagctta cgcaattaca gcagctttcg caaacattca acggagaaaa tcctaagaag
    46141 actagtttgg aacggtatgt gcttcaggtt tatcttcaag aagtgttaca agtagcaaat
    46201 gatcatctcc aacgtttaac gaaaaatcgt tatcaatttg agctagcgga taccattggc
    46261 agttatcgag ggaaaaccgg attagaaatc aatatctatg atgatcaggc aggtatgtct
    46321 cgaagtgcgc ataccctgtc tggcggtgag agttttattg cagcactttc tttagcatta
    46381 gctcttgccg atgtgatcca gacacaagct ggtggtgtag caatcgatgc attgtttatt
    46441 gatgaaggat ttgggtcatt agatgaagaa gctttggaaa tggcaatgga agctttagaa
    46501 acgatcgaaa gtgaaggaag aatgatcggc atcattagtc atgtaagaga attgaaagaa
    46561 cgagtattac aacaaataag aattgataca gaaggtagcg gacaaagcaa aatacgctat
    46621 caacttggat aaaaagggag attggtaact atgaaatgga gtattccaga aaaagtcatt
    46681 gcacgtggac gtcaatactt gcaagaaggc cgagtgttat cggttgtccc tgaccaagaa
    46741 gaaaacgtgt ggcatgcaga agtcttgggc agtgaattgt atatggttga tttggatggt
    46801 acagcaaaag agatagatta ctgccaatgt ccttattggg aggaacataa atattgtaag
    46861 catacagttg ctgtggaact ttatttacgg tcgaaaaatc tatctcgtat catgaaaaaa
    46921 gaccagccaa tgctagaacc ggtaaaagca acaagtgagg gagaaatcat tgcaaaaggt
    46981 ttttctcgtc taaaaacaca aaacaatcct caagcggtgc aacctttgat tattgaatac
    47041 caagtagaaa cgattgagac taatcagtat cacccagagc tttctatttt ggcactttac
    47101 ttgcgtatcg gttcattggc atcaccgaaa aaaacatata tcgtaaaaaa catctatgat
    47161 tttttacaag cttacgcaga aaaagaaact tacactgtta ataaacagta ccagtttcgt
    47221 ctagataaac gggcgtttca aaaagaagat caaaaaatac tcacgcatct tgcaggaagt
    47281 gctcagacgc atcaattatt aggtacgaac ggcttacaag tcaaaggaaa actagataaa
    47341 agatatctgc ttctcccagt agaacaagcc cgcttcctgt tagagcagat gaatcagact
    47401 acacgtttgc atctgcagat aaatgaacaa aacgatcaag gaatacaatt ttccgatcaa
    47461 aacaaacctt tatcattcaa agtggaaaaa tttggagaag attatttgct gcaagcattg
    47521 aatgattttg attttttctt tatgcattat cagtggggag ttatccaagg gacattttat
    47581 tctctgacga aatatcaaca aacggtttat caaacttgga aacaattgat tcgccgattg
    47641 gagaaaccag aagtagtgtt caagaaaaaa gaattaccgt ctttgtttaa agagattatc
    47701 cctctgcttt cagagatcgg cgacgtagct attgcccctg cagtagaaga ggaagtagca
    47761 gatatccccg tcgaatttat tttctttttc cgaaaatcaa aaggaaaaat ccaagctcga
    47821 gtcgatttcg tctatggtga agtcatctat tcgactgacc cgaagcatga ggtctcgaca
    47881 gaacaggctt ttcaggtgtt acgtgacaca gtagaagaga aacgagtact tgatctattc
    47941 agaatgtatc gctaccagaa aaatgaaact ggttatgaac gtccattgcc aagcggggaa
    48001 gaactatatg cctttttccg cacagaacta tctgtcttcc gtcagtttgg tgaagtcaga
    48061 cttggaagaa aattgcgaga gttgtattta gatgcgcata aacatcaacc gaaaatcgaa
    48121 gtaaccgaga ccggttcatg gctcgatatt cgattcgatg tgacagggat agaggagcaa
    48181 gaaatcgatc atgtcctgca aagcttgctg agaaatgatg ctttttatac attagaaaat
    48241 ggtcaggttc tttcttttga ttcagaagaa tttcaacaaa caagccaagt gttgcaacaa
    48301 ttacgggaat cgatacgtac agaagaagga acgatccatg tacctaaaaa tcaaggattg
    48361 atcattcaaa atcaattgga aaaaagcaat gctactttta gtgaatcgtt ccaaacgatg
    48421 gtacaagatc tcattcatcc agaaagatac caggcacagc ttcccaaagg attgaatgca
    48481 acgatgagag attatcaaaa gcaaggtttt cgatggttga agatgttagg tcattatcag
    48541 tttggcggta ttttagccga tgaaatggga cttgggaaaa cactacagac aattgccttt
    48601 ttactttcgg aaaaagaaga acggaaaagc ttctctgctt tgatcgtagc gcctgcgagc
    48661 ttaatttaca actggcaggc agaggtgaga aaattcgccc cttctttaag tatccaagta
    48721 atcaatggga ataaaaaaga acgtgaagaa ttactggcta aagacacaga tatccgagtg
    48781 acttcttatg ccagcttaag acaggatcta gctaattatc agtcgcaaaa aattgattat
    48841 ttgattcttg atgaggcaca aatggtcaaa aatagcagta cgaaaactgc acaagcattg
    48901 agagaattag ctgtacctca gcggtttgca ctgagtggga caccaatcga gaataattta
    48961 gaagaattgt ggtcattgtt tgcaacgatt atgccaggat ttttcccgac taaaacaaaa
    49021 ttcagggaac ttgccgcaga agaaattgcg caaatgattc gaccgtttat tttacggcga
    49081 gataaacaaa ctgtgttgaa agacttgccg gaaaaaacag agatgaatct atattctgca
    49141 cttacagaag aacaaaaaac tgtttattta gcttacttgc gtcaaatgcg tgaagaaatc
    49201 acatcaatgg attctgaagc attcaagaaa aaccggatcg ggatacttgc tggtctgaca
    49261 agactgcgac aaatttgctg cgatcctcgt ctgtttattg aagattacca aggcggttcc
    49321 ggcaagctcg aacaagtaaa agatctactg gtagctgcca aagagaacaa acgaagagtt
    49381 ttgctgtttt ctcaatttac agggatgctg actatcttgc aagaagagtt agccgagcta
    49441 gggatctcga cattttattt aagaggcagt acgaaaccac aagatcggtt aagtatggta
    49501 gacgcattta atgctggcga aaaagatgtt tttctgattt ccttaaaggc tgggggaact
    49561 ggattgaatc tcacgggagc agatacggtc atcttgtatg acctttggtg gaatcctgcc
    49621 attgaagaac aagctgctgg acgtgcacat cggatcggac aaaaaaatgt ggtagaagtg
    49681 tggcgtatga tctctgaagg aacgattgag gaacgcatgg attcactcca gcaagaaaaa
    49741 cgcgaactgt tccaaaaagt gatccaaggt aatgaagaac agttgacgaa actgactgaa
    49801 gaagacatcc gcatgatttt aagtgtagga gaaatcgagg agtaagagac tcgaaaaagc
    49861 gttcagtaat gggtaagaaa gcctttctaa agaagcgatt gtttatttga tttaaaaaat
    49921 agcaaggagg ctgggattcc attttatccc agcttccttg ctatcatttt tttatttcta
    49981 tttttaaagg ttatacaaag attgtcttca ttgtctctaa cagctgatca aaagaagaaa
    50041 tctcgatatc gcaaattgga gtctgttcaa ttttgcgttc tcgatggttg aaccaaagcg
    50101 cttgccagtt agcacttttt gcacctagaa catcattgtc gtaattatcg ccaacgtata
    50161 aggtctcttc tggaagcata tgaaattctt tctcagccag ctgaaaaatc tctttttctg
    50221 gtttttggaa acctgttgct tgagaaatga gcatattgcg ggaaggaatc caattgttca
    50281 attgaagttg cttcagtttt tttgtctgat ggtcagtcgg cccatttgtg ataattccta
    50341 atgggacatt cttttccttc aagaaatcga gggttttttt gacctcctca tgcaagcaga
    50401 tattatcaag ttcttcctcg taaatttttt gaaataagag gccatcttct tccgtaatat
    50461 gagggtagtc taaatctttt agtgattggc tgatccgatg tgctcgcata tattctagtg
    50521 tccaatctcc tgccattact tttgggaagt tttcatcact atgatggcgg aaccggatat
    50581 atagtggatg catatctgca tctgaaacaa gcggaacgac tcttttgacc gcgtttcgaa
    50641 atggctgctg ctgatcatac atcgtatcat caacatcaaa cacaactgat ttaatcaaaa
    50701 ttttacacgc ctttcggttt tcattgattt tttcacaaat ccttgactat tgtaacagaa
    50761 aaaattgtct aaaaaagctg ataaataaag gtttttctta ctatatttct atttccttga
    50821 cagaataagg tttttatatt tcagtttttt tcactaaaaa tcgtgaaaca cgtcaataag
    50881 tttgatgaac aaattaatca ttatggtaga agtcga
//
LOCUS       DAFKHN010000014        50227 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFKHN010000014 DAFKHN010000000
VERSION     DAFKHN010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50227
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.014"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(121..432)
                     /locus_tag="LY912_000775"
     CDS             complement(121..432)
                     /locus_tag="LY912_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBM6954489.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(434..631)
                     /locus_tag="LY912_000776"
     CDS             complement(434..631)
                     /locus_tag="LY912_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBM6954490.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1025..2752)
                     /locus_tag="LY912_000777"
     CDS             complement(1025..2752)
                     /locus_tag="LY912_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBM6954491.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2745..3938)
                     /locus_tag="LY912_000778"
     CDS             complement(2745..3938)
                     /locus_tag="LY912_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBM6954492.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4125..4769)
                     /locus_tag="LY912_000779"
     CDS             complement(4125..4769)
                     /locus_tag="LY912_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6954493.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4863..4997)
                     /locus_tag="LY912_000780"
     CDS             complement(4863..4997)
                     /locus_tag="LY912_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBM6954494.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4999..7131)
                     /gene="feoB"
                     /locus_tag="LY912_000781"
     CDS             complement(4999..7131)
                     /gene="feoB"
                     /locus_tag="LY912_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBM6954495.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7128..7601)
                     /locus_tag="LY912_000782"
     CDS             complement(7128..7601)
                     /locus_tag="LY912_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBM6954496.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8002..8226
                     /gene="nrdH"
                     /locus_tag="LY912_000783"
     CDS             8002..8226
                     /gene="nrdH"
                     /locus_tag="LY912_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBM6954497.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8385..10544
                     /gene="nrdE"
                     /locus_tag="LY912_000784"
     CDS             8385..10544
                     /gene="nrdE"
                     /locus_tag="LY912_000784"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBM6954498.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10594..11559
                     /gene="nrdF"
                     /locus_tag="LY912_000785"
     CDS             10594..11559
                     /gene="nrdF"
                     /locus_tag="LY912_000785"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBM6954499.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11648..12787)
                     /locus_tag="LY912_000786"
     CDS             complement(11648..12787)
                     /locus_tag="LY912_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBM6954500.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13096..13809)
                     /locus_tag="LY912_000787"
     CDS             complement(13096..13809)
                     /locus_tag="LY912_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBM6954501.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14063..14764)
                     /gene="nagB"
                     /locus_tag="LY912_000788"
     CDS             complement(14063..14764)
                     /gene="nagB"
                     /locus_tag="LY912_000788"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBM6954502.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14998..16530
                     /locus_tag="LY912_000789"
     CDS             14998..16530
                     /locus_tag="LY912_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBM6954503.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16721..17923)
                     /locus_tag="LY912_000790"
     CDS             complement(16721..17923)
                     /locus_tag="LY912_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6954504.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(18005..18694)
                     /locus_tag="LY912_000791"
     CDS             complement(18005..18694)
                     /locus_tag="LY912_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBM6954505.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18800..19168)
                     /gene="rplL"
                     /locus_tag="LY912_000792"
     CDS             complement(18800..19168)
                     /gene="rplL"
                     /locus_tag="LY912_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBM6954506.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(19221..19724)
                     /locus_tag="LY912_000793"
     CDS             complement(19221..19724)
                     /locus_tag="LY912_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBM6954507.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19928..20055)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(20134..20823)
                     /gene="rplA"
                     /locus_tag="LY912_000794"
     CDS             complement(20134..20823)
                     /gene="rplA"
                     /locus_tag="LY912_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBM6954508.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20927..21349)
                     /gene="rplK"
                     /locus_tag="LY912_000795"
     CDS             complement(20927..21349)
                     /gene="rplK"
                     /locus_tag="LY912_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBM6954509.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            21692..22360
                     /gene="sdaAB"
                     /locus_tag="LY912_000796"
     CDS             21692..22360
                     /gene="sdaAB"
                     /locus_tag="LY912_000796"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBM6954510.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            22373..23245
                     /gene="sdaAA"
                     /locus_tag="LY912_000797"
     CDS             22373..23245
                     /gene="sdaAA"
                     /locus_tag="LY912_000797"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBM6954511.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(23336..24355)
                     /locus_tag="LY912_000798"
     CDS             complement(23336..24355)
                     /locus_tag="LY912_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBM6954512.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(24528..25433)
                     /locus_tag="LY912_000799"
     CDS             complement(24528..25433)
                     /locus_tag="LY912_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBM6954513.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(25492..26037)
                     /gene="nusG"
                     /locus_tag="LY912_000800"
     CDS             complement(25492..26037)
                     /gene="nusG"
                     /locus_tag="LY912_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBM6954514.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(26138..26308)
                     /gene="secE"
                     /locus_tag="LY912_000801"
     CDS             complement(26138..26308)
                     /gene="secE"
                     /locus_tag="LY912_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBM6954515.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(26332..26484)
                     /gene="rpmG"
                     /locus_tag="LY912_000802"
     CDS             complement(26332..26484)
                     /gene="rpmG"
                     /locus_tag="LY912_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBM6954516.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            26646..27290
                     /locus_tag="LY912_000803"
     CDS             26646..27290
                     /locus_tag="LY912_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBM6954517.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(27346..27849)
                     /locus_tag="LY912_000804"
     CDS             complement(27346..27849)
                     /locus_tag="LY912_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBM6954518.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27862..27908)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            28446..29411
                     /locus_tag="LY912_000805"
     CDS             28446..29411
                     /locus_tag="LY912_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBM6954519.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(29510..30682)
                     /locus_tag="LY912_000806"
     CDS             complement(29510..30682)
                     /locus_tag="LY912_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954520.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(30669..31814)
                     /locus_tag="LY912_000807"
     CDS             complement(30669..31814)
                     /locus_tag="LY912_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954521.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(31828..32752)
                     /locus_tag="LY912_000808"
                     /pseudo
     CDS             complement(31828..32752)
                     /locus_tag="LY912_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32869..33948
                     /locus_tag="LY912_000809"
     CDS             32869..33948
                     /locus_tag="LY912_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBM6954522.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            33980..34573
                     /locus_tag="LY912_000810"
     CDS             33980..34573
                     /locus_tag="LY912_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6954523.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(34683..34910)
                     /locus_tag="LY912_000811"
     CDS             complement(34683..34910)
                     /locus_tag="LY912_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBM6954524.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(35013..37601)
                     /locus_tag="LY912_000812"
     CDS             complement(35013..37601)
                     /locus_tag="LY912_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBM6954525.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(37621..38280)
                     /locus_tag="LY912_000813"
     CDS             complement(37621..38280)
                     /locus_tag="LY912_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBM6954526.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(38329..38832)
                     /gene="trmL"
                     /locus_tag="LY912_000814"
     CDS             complement(38329..38832)
                     /gene="trmL"
                     /locus_tag="LY912_000814"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBM6954527.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(39053..39919)
                     /locus_tag="LY912_000815"
     CDS             complement(39053..39919)
                     /locus_tag="LY912_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBM6954528.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            40028..40669
                     /locus_tag="LY912_000816"
     CDS             40028..40669
                     /locus_tag="LY912_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBM6954529.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(40731..42092)
                     /gene="mgtE"
                     /locus_tag="LY912_000817"
     CDS             complement(40731..42092)
                     /gene="mgtE"
                     /locus_tag="LY912_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBM6954530.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVT
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(42110..43009)
                     /locus_tag="LY912_000818"
     CDS             complement(42110..43009)
                     /locus_tag="LY912_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBM6954531.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(43011..43808)
                     /locus_tag="LY912_000819"
     CDS             complement(43011..43808)
                     /locus_tag="LY912_000819"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBM6954532.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(43786..44490)
                     /locus_tag="LY912_000820"
     CDS             complement(43786..44490)
                     /locus_tag="LY912_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBM6954533.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            44621..45196
                     /locus_tag="LY912_000821"
     CDS             44621..45196
                     /locus_tag="LY912_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBM6954534.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            45314..45991
                     /locus_tag="LY912_000822"
     CDS             45314..45991
                     /locus_tag="LY912_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBM6954535.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(46070..47878)
                     /gene="pepF"
                     /locus_tag="LY912_000823"
     CDS             complement(46070..47878)
                     /gene="pepF"
                     /locus_tag="LY912_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBM6954536.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(48054..49052)
                     /locus_tag="LY912_000824"
     CDS             complement(48054..49052)
                     /locus_tag="LY912_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBM6954537.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(49278..49931)
                     /locus_tag="LY912_000825"
     CDS             complement(49278..49931)
                     /locus_tag="LY912_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBM6954538.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        15044 a        10531 c         8788 g        15864 t
ORIGIN      
        1 ctattttttt cttccattac gattccccct acaaactata aatactttta tgtcactgat
       61 tcaatatacc tatttttcta atcaaaaaat tttgagacat atttaatatt ataagtatca
      121 ttaaaattga gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct
      181 tccaatttca ctcaaatttc ttattaattc ctcttgatat tcagtgaatc ttattttatt
      241 agtataagca gtaaaatata gataattcac caatctattt attaaaggac cgggatctaa
      301 ttcatatttt tgtttttcta attttaaata taccttttgt aaaacctcaa gaatatcaga
      361 atatttagga tctttactta tagatatatc attatataat tcatgaacaa tttgcttagc
      421 attttttttc attttagcac ttccctggaa ttgctccacc taaaaaacca cctatagaca
      481 ttcctgcaat acaagtagtt gccttggccc aatcgaccgt acatttattt ttagtgcaat
      541 acactccatt tccataatat tttccactat gagtggtacc cccatagata agttgtgtct
      601 ctttaataga caaaattttt aaatgtttca taatctaatc acccctaaat taatgttttt
      661 agactattat tctaacattc attaaatttc aaaaaacaat tccttcttga aacgtagcaa
      721 aataattcct gaataagaat ttaatcactt ttaagtatat aaactatgta tattctttaa
      781 tattttttga gaatgcactt cgtacataat aaactttaat cacattagtc tttcatacct
      841 acgatcgatc tctttgactc gcacccataa attcataata gtttgtcggc gtctttggac
      901 gtttcgaaga tgagctacgc attctctttt tttatagaca aaaaagatag agacgaacat
      961 ggagcttcca aatttggata tttgatccaa ttttggaagc tccatttatt tcgtgtctgt
     1021 ctttttattt tttccagctt tcgactaatt cttggttctc tttgatccag tcttttgctg
     1081 cttgctgtgg atcttttcca ttgttgattt ccaacataac tttttccata tctttttctg
     1141 accaatggaa attgtctaat actttgtaag cttctggctg gtcttctttc aatccttttc
     1201 gaaccatcgt atggatctgc tcttcgcttc ccattccgtt ttcaggatct tctaagtatt
     1261 tcagatcata tttggcaaac atccaatgag gtgtccatcc tgtaactaca attggttcgt
     1321 gttttttgat cgcttgacct agtgcaacgg tcattgctcc tgaagaagat gtctctactt
     1381 tccagtcttt caagttgtca tatttttgga tcgtgttttc agcagccgta actacaccag
     1441 ctcctggctc gattcctatg attttcttac ctgcctgatc ggttaactca tcgatcgaat
     1501 ttacatccat gtaggctggc actgctaaac caacttttgc tcctgtcaaa ttggcaccta
     1561 ggtcttcgac ttgatcttta tattgtgcat attgtgaacc atgagtttta ggtagccaag
     1621 ctgaaaccat ggcatctgac tcgccatttg aaacagattt ccacatgatt gaattatcta
     1681 atggcgtcat cgttacatca tagcccattt gtttcaatac ttcaccgact acatttgttg
     1741 aagcaacttc tgtatcccat tcaacataag ataagttgat acgttttgtt tctttggcag
     1801 atgaaaaact ccctatacca atcgcaccta agatcactac tactacagca ccaatgatca
     1861 gtccttgacg ttttttactt ttctgtgttg ttgctcctgc agctttttta ttgtttggct
     1921 ggttcaaatg ctgtgtaaaa cggtcaatga tgattgctaa gataactaat gcaaccccgt
     1981 tgacaaatcc attcccgact tgtgctcttt gcaatgctga taatacgccg cgtcctaagc
     2041 cgggtgcacc gatcatagag gcaataacga ccattgaaag tgacagcatt gttgtttgat
     2101 tgatccctgc catgatcgta cttttagcta aaggcaattc tagtttgaat agtttttgac
     2161 gacttgtgct cccgaatgaa tcagaagctt ctactaattc tttaggaact tgtcgaatcc
     2221 ctaaattcgt aaaacgaacg gttggtggca gagcaaagat gactgaggca aatacccctg
     2281 gaaccatccc gataccgaaa aatgcaactg ctggaatcaa ataaacgaat cctggcattg
     2341 tctgcataaa gtcaaggatc ggtttgataa tactttgggc tttactgctt tttgccatca
     2401 agatccctaa tggtacccca atgatgatcg agatcacact agataaaaga acaagtgtga
     2461 cagtattcat caaatcattc catagacctt ggttataaat aaaccataga ccgattaatg
     2521 tgaacaacgt aagtcctgga cgtttcttag aaataaagaa agctgctacc gtcaataaca
     2581 agataaacaa aggagctgga atcactaaca gtaaatttgt aatccccgac atcactgcct
     2641 gtccaatcgt ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga
     2701 tattttctac ccagtttgcc actggtaatt gatagttcaa tagattattc atgttcactc
     2761 acctcgcttg tttctgctaa tgcttcaatc acactacctc ggatgacgac accttttaat
     2821 tttccatcct ctacaactgc aagtggagtc ggtgagtcat aaataatatt gaaaatatca
     2881 cttaccacca tgtctttccc aatcaccgtc acattttcat ctaggaagtc gatcaatgga
     2941 cgtttttgct tcctagcttc taacgcttga tctgcagtga tgatcccttt caggtgtctc
     3001 tttctgtcaa cagccatcag catgctgact tcttcattac gcatccttgt caatgcaacg
     3061 tttggtccat cagattcgat attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta
     3121 agcactttgg aacgatcgac ttcttccaca aattcacgta cataatcatt tgctggattg
     3181 gtcaatattt cttcacctgt tccgatctgc atgatttcgc cgtctttcat caaggcgatt
     3241 ctgtccccaa tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat cgttttttga
     3301 acattggctt gcaggtccag taattcgtct tgcatttctc gccggatcag cggatcaaga
     3361 gccgagaacg cttcgtccat cagcaagatc tcaggatcat ttgctaaagc tctggctagg
     3421 ccaacccgtt gttgcatccc accagataac tgactaggat attggtcttt aaatgaaagc
     3481 aaactagaat tttctaatgc tttttctgct ttttcttgtc gttcttcttt aggtacacca
     3541 cggacttcta acccgtattc tgtattttcc aagatcgttc gatgtggaaa cagaccgaag
     3601 ttttggaaaa ccatattgat tttatgacga cggacttctc gcaattcttc tttgcttaac
     3661 ttcgatacat cttctccatc aatatagata ctgcccgaag ttggctcaat cagacgattc
     3721 aatagacgga tcaatgtgga tttcccactc ccggaaagcc ccatgatcac gaagatttct
     3781 ccttctttta cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt tttctttaaa
     3841 atctccgttt tcggctggtg atcattcatc atatctaaag cggcttgtgt ctttttacca
     3901 aatatctttg ttaaatgttt tacttctact tttaccaaac aaattctcct tttttatgta
     3961 aattcatttt tctttctgaa aaaagtgacc acactatgtt aacatcatgt agtcactttg
     4021 tcaaaaatga aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa
     4081 taaaaggttt agccaagtta atattttttt aatatttcac acaatcattc tgcaagctga
     4141 tgctccgggt aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc aataaaatga
     4201 acgatgtccc ctgccgtaaa tttagcatag gggccaggtg aaacaagcag ttcttcatta
     4261 tgagaaattg cgataactgt ggcgccagtc gcctgccaga tattcaactc gctaattgaa
     4321 cggtccagat gcattgcttt ttctgataaa gataattcaa acggaagtaa aggattcatc
     4381 ttatgtattc gcttcgtttg attgaccagc tgatccaata attgagaaaa atgattcagc
     4441 tcatcttgtt gcttctccac acttgccatg atttctgctt ttgtatcttg gatggattgt
     4501 acatcttgat attgcaatag gaaatctttt gctttttcct tcgaagcaac aaatgcccca
     4561 cttccatgcc gtacttccat gattccaaga tctaccagca cattgatagc cttgcgggta
     4621 gtctcaggag aagcattgta cgtactggca agtgttgagc gggcatggat cttctcaccc
     4681 actttatatc ggttttcaac gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc
     4741 gggcggacga tttttttctt tccagacatt ttctttcctc tttctttttt tactttccct
     4801 catcttacta tgctctagca aaataagcaa aaaaggggag aatagcctct tgcaacgact
     4861 gatcatcgct tgatctgttc cttttttact gggcaagctg tttgacagtc atcacaattc
     4921 ttaccggatt ttaaacgagt atagacaatt gcgcctgcac ttccaaagat taacacactt
     4981 aataagaatg tcgccatcct attcctctcc ttctaatgac aatatagtat aaaactggtt
     5041 cttggatttt ggctgacgga acaaaacata aacgagtcct atcatcagta aaatagcaag
     5101 atacgtccct aacgctacct gtccaccctc caataagtgt cccaactgat aaatcacaaa
     5161 actaactaaa taagctaaac cgcattgata gcctatggcg atccaagtcc atttcttggc
     5221 attcatttcc cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa
     5281 ggctaacaat gaataagctg ctgcgggagt atatgtgtgt tgtagcactt gccagatttc
     5341 tctgccattt tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc caataatatt
     5401 ttctttagcg accaatcctg taatcgctgc gactgttcct tgccagtttc cccaaccaag
     5461 cggctgaaaa acaactgcca ggattcgccc gaaaaaggct aagatacttt ggtcttcaga
     5521 aacaggttga gcataaaaat tataagaaga gctgaaccag atcacgatac tagaaacaaa
     5581 gataatcgtt cctgcttttt taacaaaaga cttgctgcgg tcataggttt gtcttaggac
     5641 cgctgaccat tgaggaaaat gatatgcggg caattccatg ataaaaggag ctgtatctcc
     5701 agcaaacaaa cgtgtttttt tcaagctgat tccagagaaa ataattgcag tcataccaag
     5761 aaaataggca gaaggagcta cccaagattg atgaggaaaa aaggcccctg ctactaaggc
     5821 aataatcggc aactttgcag aacaaggcat gaaggttgtg accatgatcg tcaaacgacg
     5881 atcttgctcg ttttcaatcg tgcgactggc catgacgcct ggcactccac atcctgtagc
     5941 aatcagcata ggaatgaagg attttcctga aagaccgaat ttcctgaaaa gtcgatccat
     6001 gacaaaagcg atcctcgcca tatatccgca gtcttccaga aagctcaagc ataaaaacaa
     6061 tataatcaat tgcggtagaa atcctaacac tgctcccacg cctgcgatga tgccgttcaa
     6121 gatcagctcc tgcatccatc ccgctacttg ccattcagct aacaatctgc caacatgttc
     6181 tggtaaccat gtaccaaaca atgtgtcatt gatccaatct gtccccattg ttcctactgt
     6241 ttgaatagcc agataataga tcagccacat cacaaatgcg aagatcggca aggctaacca
     6301 acgattcgtt gcaatctgat cgattttgtc actcatcgat aattggaaag aatcatttga
     6361 cacaacacag agtgtacata gttgggtaat aaattcataa cgttcattga ccagaatcgt
     6421 ctcactatcg tcgtccaata gtttctctgt taactggatc agttgctcga tctctttttg
     6481 ctgagaaact gctatctcgt aatcctctct taccttctga tctcgttcaa aatatttcat
     6541 tgcataccag cgtttcttgc cgctttgttc tcctagtaca tcttcaattt catgtaaagc
     6601 tgcttctaaa cgtggatcat atgtacaggg aacaggaata gaaggccgct tttttgcaga
     6661 ctcctgaatc ttttcgatta gtttttcgat tccttgcttt ttcaatacgc tgattggtaa
     6721 aactggtaca ccaagaccat aggaaagctt ttctagattg attttttttc cttctttttt
     6781 gatgacatcc atcatattca gaccaatgat cataggaatg tctaaatcca ataactgcgt
     6841 agttaaataa agatttcgtt ctaaattggt agcatcaata atgttgatga tcagttcagg
     6901 ctgttcctga accaaataat ctcttgcaat cacttcttct ggtgtataag gagacaaaga
     6961 atagatgccg ggtaggtcct gaatatgaat gttcggattt tttttcaacg atccttcttt
     7021 tttttctact gttacgcccg gccaattccc tacatattga ttcgaaccag tcaagagatt
     7081 gaacaagcta gttttcccgc tgtttggatt tccgactaac gcgatattca ttctttttcc
     7141 tccctttgta tcaagattag ttcggcctct gactttcgta acgtcagttc ataccctcgc
     7201 actgtcagtt cgattggatc tcccagaggg gctagttttc ggataactat ttttacattt
     7261 cgcgtcaatc ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg
     7321 acgatcccag tctctcctgc ttttaattga tcaagagaag tccagctttc agaggaagca
     7381 gtctttttat tgacaaagat ttgacctagt atttcccgac ttactgccac tcgatgactt
     7441 tttaccagta aaatggcatt gttgcctgat aaattgacga cgacgatttt acttccggca
     7501 acgatcccga tattttgcaa atggcgtttt gttttttctt ctgtttcgat tcgttcgact
     7561 tgataaacga aattctgctt tgcctgcgct aaggtctgca tattgattcc tctcttgtga
     7621 aataaatcat gtattaaaat cattcattat atgttctaat tttcttacgt gttacgcaaa
     7681 taaatgagaa tcattctcac atagaatact ctcggtaatt gagaatgtca attatacttg
     7741 tgatattatg agcgaatctt tagtattgat agataaaaat gagaaaaaaa tatttcttca
     7801 tagttttcca caattttttc tctattaaat ttgctatttt cccacacgat acttgttttc
     7861 agctcttttt tcaaaaacac aaaacttagt attccacagt ttccacaaca caatatgtag
     7921 tgtttgttgt ttgacttttt tactaagagt tttatactat ctattataga taataagaat
     7981 gtgttagagg aggcactcac catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa
     8041 tgtaagatgg tcaaacggtt tttaacagaa aatcaaattg cttttgaaga agtcaatatc
     8101 gatgaacagc ctgaagcagt agactggttg aaagcacaag gattccaaag tgttcctgtc
     8161 attacttctg atgcagaaac agttatcgga ttccgtcctg atcagttgcg taaacttgcc
     8221 agctaacatg actaaaagaa tcaaaacgtg atacatggat ttgaagggct tgagacagca
     8281 ccagtttttg tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat gcaatgattt
     8341 gcaatcaagc atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt
     8401 tacaagatgt cagttatttc aagctgaata atgaaatcaa tcggccagtc aatggtcaaa
     8461 tccctttgaa taaggataaa gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa
     8521 atacgatgac ttttctatct attatggaaa aaatcaatta cttgatcgat caagaatata
     8581 tagaagcaga attcattcaa ttgtattcac catcatttat tgaaaagcta tatcaatttt
     8641 tggacgagca acatttttct ttcaaatctt ttatggctgc ttacaaattt tattctcaat
     8701 atgcgttgaa aaccaacgac ggttccgctt atctggaaac ttatgaagat cgagtagcct
     8761 tcaatgcgct ttactttgcg aacggggatg aagaattagc acttgctctt gcagacgaaa
     8821 tgatccatca acgatatcag ccagctacac cttctttctt gaatgctgga cgtaaacgtc
     8881 ggggcgaatt ggtgtcttgt ttcttgactc aagtcactga cgatatgaac tctatcgggc
     8941 gctcaatcaa ctctgctttg caattgtccc gtattggtgg cggcgtaggg attactttat
     9001 caaatcttcg tgaagccggc gctcctatca aaggatatga gggtgctgca agtggtgtcg
     9061 ttccagtcat gaaattattc gaagatagtt tcagctattc taatcaatta ggtcagcgtc
     9121 aaggagctgg cgtggtttat ttgaacgttt tccatccaga cattattgct ttcctttcag
     9181 caaaaaaaga aaatgcagat gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg
     9241 tacctgataa attttatgaa ttgacacgta aaaacgaaga tatgtattta tttagtccat
     9301 atagtgtcga aaaagaatat ggtgtcccat tctcttatgt aaatattaca gctgagtatg
     9361 atcatctagt tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa
     9421 atgaaatctc aaaattacaa caagaatctg gctatcctta cgtaatcaat attgatacag
     9481 cgaaccgcga gaatccaatc gatggcaaga tcatcatgag taatttatgt tcagagattt
     9541 tacaagttca aacgccttct gtgattaacg gcaaacagga atatgaagta ttaggaacgg
     9601 atatctcatg taacttaggc tcgacaaata tcgtgaattt gatgcaaagc cctaactttg
     9661 gtcaatctgt gcgtacgatg actcgtgcat tgacatttat tacagatgca tctgatatcg
     9721 atgtcgtacc accgatccaa aacggaaata agctgaatca tacgattgga ttaggtgcca
     9781 tgggcttaca cacttatctt gcaaaagaac aaatggaata tggctcagag gattcattag
     9841 actttacaaa tatttacttc atgctgttga attattggac acttgttgaa agcaacaata
     9901 tcgctcgtga aagaaaacaa gttttccata attttgaaaa atcagcttat gctgacggca
     9961 cttatttcga aaaatacgta actggagaat tccagccaaa atcagaaaaa gtcaaagcat
    10021 tgtttgaagg catttttatc ccaactgctg aagattggaa tgctttgaaa caagcagtaa
    10081 tgaaagatgg actgtatcat caaaatcgct tggcagtagc accaaatggc tcaatttcat
    10141 atatcaacga tacgagtgca agtattcatc ctatcactcg catgatcgaa gaacgccaag
    10201 agaagaaaat cggtaaaatt tattacccag cgccttatct atccaatgag acgattccgt
    10261 attacacttc tgcttatgat atggacatgc gtaaagtaat cgatgtttat gcaatggcac
    10321 aacaacacgt cgatcaaggc atgagtttga ctttattcat gcgttctgaa atcccagaag
    10381 gcatttatga atggaagaca acaacgaagc aaacgacacg tgatttgaat attttaagac
    10441 attacgcttt ccacaaagga atcaaatcca tttattacgt acgtaccttt actgatgatg
    10501 cagaagaaat cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat agatagattc
    10561 gcttattcat attttaatta aaggagcatt ctcatgtcag aaacatatta tgaagcaata
    10621 aactggaatg aaattgaaga tatcattgat aaatccactt gggagaagct gacagagcaa
    10681 ttttggctag atacacgtat cccactttca aatgacctag atgattggcg tacattgtct
    10741 caattggaaa aagatacagt aggacatgta tttggcggtt tgacactgct agatactgtc
    10801 caatctgaaa gtggcatgga tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc
    10861 gttttgaaca atattcaatt catggaatcc gttcatgcca aaagttattc ttctattttt
    10921 agtacactga atacgaaaaa agaaatcgaa gaaatttttg actggacaaa tacgaatcct
    10981 tatctgcaaa aaaaagctga gcgtatcaat gaaatctaca aacacggtac accgctagaa
    11041 aagaaaattg ccagcgtctt tttagaaaca ttcttgttct attcaggttt ttatactcct
    11101 ctttattatt taggaaacaa caaattggct aacgtagcag agatcatcaa actaatcatc
    11161 cgagatgaat ctgtacatgg aacctacatc ggttacaaat tccaattagg attcaacgag
    11221 ttacctgaag cagaacaaga aacgttaaaa gactggatgt acaatcttct ttatgagctt
    11281 tacgaaaacg aagaacgtta tacagaagaa ttatacgatc caatcggctg gacagaagaa
    11341 gtcaagacat tcctacgcta taatgccaac aaagcattga tgaacctagg gatggatcca
    11401 ctctttccag atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc
    11461 acaagcaacc atgacttctt ctcacaagtc ggaaacggct atttgttagg tcatgtagaa
    11521 gcgatgaaag acgacgatta tttgattgga ttggaataag gatttatttt aattcaaaaa
    11581 tttttcgaaa aataaaaaga gtttagcgta cagatatttt aaatgtacac tgaactcttt
    11641 tttatgctta ttcacttgtt tcttccagca cttttggact gtctaacttt tccgaaacat
    11701 gttccattct tctcaataaa tagattttcc ggatatttaa tattatcgtc ttaatcactg
    11761 catagacagg tatgcaaatc agcatgccta atattcctgc gacacttcct gctccaatca
    11821 ataccaagat gatcgtcaaa ggatggatat tcattgattt cccaaataac aacggcttga
    11881 tcaaatttcc atctaattgt tggatcacta aaatcgacaa cgccatatac aaagcttgaa
    11941 atggagagat aaacaaaccg acaatgattg ctggtaccgc tccaataaaa gggccgacat
    12001 acgggataat attcgtgatt ccgcaaatga ccgcaagcaa caagctataa ggctgatcga
    12061 atattctcat tgccaaaaag ctcattacac caataatcaa agcatctaag atcgtactgc
    12121 tgatataggc agataatgtt tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa
    12181 tcgctttcgg aaagaagtga gacaacgcat caataaattt gtgcccatcc ttgaacataa
    12241 atagcaaaat aaatggaacg gtaaataaca aaataaaaaa ttgcatcata aatgaaatga
    12301 tttttgagac acttgcagat aaactgacta atatgatatt gaacaaatta ctaagagata
    12361 aatttgctga tgctaattgt tcttccaaat tgaaattttt aaactcttcc cgctgcgcca
    12421 attcatttaa ccatttgctt gtttcatctg catacattgg caagctctgg gtcaattgaa
    12481 ttgtctgttc cattaactga ggcactacat tcatgacagt taaaacaact aaaatgatta
    12541 cgaccaaaaa cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa
    12601 caacgattgg atcgaacata taatagataa aaccagcaac aagcaatggt aaaaaaactg
    12661 ccgaaagcat tttcaatatt ggactaaaaa tattcggcat ttgtaaaata aagtacacgc
    12721 cgatgatcgt gagtactagc tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg
    12781 attgcataca tctcctccaa ggtcctttga tacttctatt ctatcattta acaaagagtt
    12841 acgcgctgag attttcattt gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt
    12901 agacgagtac ttaaacaaaa acacggtttg gagtagtgac aaaaattata ctgcagtccc
    12961 tttttccaaa taaacggtgt tcaaaagctt gcatcttcgt aataagccca gccaaacgaa
    13021 aaatataagg aactattttt atttggctgg gcttattact tgatgtagga catctatttt
    13081 acaacctcag atcatttatt gcgcaatact gactaaatgc aactttgtga tatttttgtg
    13141 tacggacaac tcctcgatca catcggcata agtgagccct tttggaagat caatcgtata
    13201 gatatttttg tacactcggt agtcatcaac gaattttacg tcaaaattca catcttcgat
    13261 tacgatattt ttctcttcaa aataatcggt aagaaaatct ttggtttctt ttctatggat
    13321 aaattggatt tctaactttt tagtcgtagg tacatggatc acgcgtttca ctactgtgag
    13381 tgcaatagca atcccgataa aactgatgat cgcaatggaa tagtaaccca tgccgatggc
    13441 gatccctaat ccagcaattg cccataaaga agcggcagtc gtaagtcccg tcaccgattg
    13501 tttcgtgacg atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat
    13561 cagccttgct tcatctgaac gaatcgttcc agcaagctgt ggatactcta aagcatctct
    13621 taatgcacca ctagcgatct caacttggat caatgcaatg atacatgctc ccatacaaac
    13681 taaaatatgc gtacgcatac ctgctggacg atttttatat tgtcgttcaa aaccgattgc
    13741 tccgccaaat agcatagcga tccctaaacg taaaataatc tctggaattg tcaataccat
    13801 atcattcatc taaacaccct ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa
    13861 agtgcaattt ttacctctta cgaaaaaagg actgtgacaa aatttttgtc atagtccttt
    13921 ttatgaataa acggtgttca atcagctgac cctcggtatt actcaacaaa cggcaaaata
    13981 tggggagcta tttttccttt gtcttctcta atactcaggt caaaacgctg atttcacaac
    14041 ctctttagcc tactattgaa aattacaact tacttgctgc ttcttcatcg atgatcacaa
    14101 caacattgtc gtgattttgc aatacacttg ctggcaaatg attcgttaca ggtccttcaa
    14161 tcatcccttt gattgcatca gctttgcttt cgccaaatgc catcaagacg atttctttac
    14221 ttttcataat tgaaccgatt cccattgaaa cagcttttgt tggtacatct tctgctttat
    14281 cgaagaatcg tttgtttgca ttgattgttg attctgttaa gtcaactact gaagtcgttc
    14341 cgtcaaatga agcaccaggt tcattgaaac cgatatgtcc attttgcccg attcctaaga
    14401 tttggatatc gattggatgt gcatcgatga tttgatcata ctttttgcat gctgcttcca
    14461 gatcttctgc ttttccatct ggtacaaacg tttctttgaa tggtttttta tcaaataatt
    14521 ggacatccat gaaatgacgg tagctttgtt catctgaacc gcctagtcca acgtactcat
    14581 ctaagtttac agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt tctttatata
    14641 aagtaactgg tgtgcttcct gttgccaatc ctaatacttt tgcacctttg ttcatacctt
    14701 ctttgatgat ttcaaatgct ttttttccgc cttcttcagc gttttttaca cgaatgattt
    14761 ccatagtgat tgctccttta tattttggta tagcccaatt atagcattct ttttttcttt
    14821 ttacaataat tagtatagac caaattgcat ttttttcatt ttcttgacaa taaataggaa
    14881 tccgtgttag gtttcataag atggttcaat caaacaatcc atgttgcatg aaaaccaagc
    14941 aagtgattca ctgtggacgc tttatgtctg cagttttttt atgaaaaagg agttattatg
    15001 agtatactga cattaaacaa cattacccag caatttggcg acaaaatcct ctatgaaggt
    15061 gtcgatctgc aattaaatgc tggcgaacat cttgggctga ttggacaaaa cggagccggt
    15121 aaaagtacat tgattaaaat catcactggt gagatcttac cagatgacgg acagatccat
    15181 tggcaaaaaa atattcacaa aggttacctc gatcaatatg tggaagtcga tgaaacatta
    15241 acaatcgaag aatttctaaa aactgcgtac gcaaaagaat acgaaaagga agaaaaaatt
    15301 gcttttcttt accaaacata tagcgagacc ttcgatgatt ccttgctgga aaaagctggg
    15361 aaactccaaa cggaattaga ccaaggagtg ttttatcaaa tcgacacctt agttgctgag
    15421 atgagcagcg ggttggggat cgatgtctta ggtttagatt cactgttgaa aaatctaagt
    15481 ggtggacaac gttcaaaggt gattttagca aaactacttt tagaaaaccc agatgttctg
    15541 atcttagatg aaccaaccaa tcacttagat gatcagcata tccaatggct gacgcagttt
    15601 cttcaggatt ttgacggtgc gtatatcgtg atttcccatg accaagaatt tcttgatcag
    15661 atcaccaccc atatcgcaga catcgagttt ggaaagatta ctaagtatac tggccatcta
    15721 aaacaagcat tgaaacaaaa ggaacaaaat cgcgaaagct atttgcgcca atatcatgct
    15781 caacaaaaac aaatcgaaaa gaccgaagct tatattcgaa aatacaaagc cggttcccga
    15841 tcaacgatgg caaaaagccg acaaaaacaa ttagataaaa tcgaacggct gacgcctcca
    15901 gcttcagcaa gtaaagctgt ctttgatttt ccattctcgc ctattgtcac gacattagca
    15961 gtggaaacaa ctgatttagt catcggatat gatcgaccgc tacttgcacc catcaatttg
    16021 accatccgct ttggtgaaaa tattgccatt cgaggcttca acgggattgg aaaatctact
    16081 ttattaaaaa cactgatcgg tgagattgaa aaaataagtg gcgatttcca cttcccagat
    16141 aacacaaaaa tcaattactt ttcacaagat ctgtactggg aaaatccatt agaaacacca
    16201 ctacaatatt taagcagtca atttccaaaa gcgactatca aagaattacg tcgccaacta
    16261 gctaaagcag ggttagttaa tcaattagca agtgaacctc tcactacatt aagtggtggg
    16321 gaacaaacta aggtgaaact tgcacagttg acaatgaacc aaggtaattt actgattctc
    16381 gatgaaccga cgaaccatat cgatcaagaa acgaaagaaa gcttacaaga cgggatacag
    16441 aaatttccag gaacagtaat catcgtctct catgaacaag aattttatca agatcttgtg
    16501 caacgagtca ttgagattga accaaaataa acgtttgatt gaatagttga aaaaaaggag
    16561 ctgtgacaaa agttttgtca caactccttc ttctgaataa atggtggcca attagctgac
    16621 cttcggtatt agctcaaaaa acggcaaaat atgaggagct atttttattt ggctattctt
    16681 attacttgat gcagaacagc ttttcacaac ctcttttcgt ctatttttta ttttcgagat
    16741 ttctctttcc tttaaaaaca actgtttgaa agaagaacgc acatccttga aaaacaagcc
    16801 cgctaaccgt tacacctaac cagccatact gctgccacat tgtcgtccct agcaatgaac
    16861 cagccgcacc tccaataaag tacataaaca taaatacagt attatttcgg ttgcttgctg
    16921 cttcacctag cccttgtact cgtgtttgat tggcgacttg accaaattga ttcccgacgt
    16981 ctaataaaat aatagctaaa agcaaaatgg ccaaatggct tccgccaacc aataaagcaa
    17041 taaagcttat tgtttgcata acaagtccca tatacacgat ttttctttca gaataagaat
    17101 ctgccagtcg tcccacgata ggtgcagcaa ctgctccaga caaaccaaaa atcgctaata
    17161 tccctgcttc gaatgttccc caattgtagg cgggactgct gatataaaaa atcaacgtag
    17221 accaaaagat cgaaaatgtt ccaaacatga aaaatccact gactgccgct tctcttaata
    17281 gacgttgaga agcaactaaa tgcggcaaac ttttaagtga atcaaggtat gaaacagctg
    17341 tactactttg ctggacagaa cgcggcattt tccagtaaag cagaagtgta agaattccga
    17401 ctgcacataa agcaaataaa tagatcatcc gccaagaaaa aagactggca acaataccag
    17461 ataccgtccg agaaagcaaa atccccacga gtaaaccgct aagcaatgta cccatgacct
    17521 tccctcttgc ttttggtccc gctagtaccg caccgtaagg aatgatgatt tgcggcacga
    17581 tcgaaagtaa tcctattaaa aaagaagcgc atgcaaataa cgtaaacgaa ggcgcaaaaa
    17641 aagcggccaa cagagagacg gcagataacg ctgccattcg aatgatcaat tttggacgat
    17701 ccaccacgtc ccctaaagga actaaaaaca gtaaccctaa cgcatagcct aattgggtca
    17761 acatcgtcaa tatcccgact gcacttgtgc taacagataa actagctgct acttttgttc
    17821 caatcggctg gatgtaatac atattggcaa caacaacgcc acaagtgatt gataatagta
    17881 aaataagcga agttgttaaa ggtttttttt cattactctt cattgatttc ccccatttcc
    17941 tatcttagtt tacaacttat ggaaaagatt ggaaatagaa aaatacaact attcgccaca
    18001 cttattattt gtgcttttgt tttccttgtt ttttcttgcg atctttataa atgaagacaa
    18061 ctaaccctac tagcacagta acacttgcaa ccaacgtgac tgcagttttg ttatatccgt
    18121 gaaacagagc ttctccacca cacgcataca acacagacga agggatgact ccaatcacga
    18181 tcgacaatat gatttgctgt agaggcaatt tcatcgcatc tgcagcaaaa ttgaccatag
    18241 aagatggaat aaccggtatc atatagccta acattacacc tatttttgga tgtttcattt
    18301 gtcggattgc ttgcacccaa tgattcgttt cggttttctt atctaaaaat tttaagcgat
    18361 gcataaggaa aattgcagtg atgttaccaa gagcattacc caaaatgttg atgatcgcac
    18421 ctgtcagtgg tccaaagctc aaaccagcaa tgactccaac tactgaagta ggaatacctg
    18481 gaacagcaca catcaccgct gtcaatacga tcaagagtat cgatgcaaaa gtcccatgcg
    18541 aacgaatatg tgcgagtagc tctgccttac tcgctctcgg atttaaaaat aattggatgt
    18601 ctgtctgata ttctaaatac aaccgatagc ccactaccag tatcagaatg attcccaacg
    18661 agatcaatat caatcggatt attttctttt tcatatttcc tcctgaaaaa aatctatatt
    18721 cattaaataa tagtttaaca taaaaacaaa aaagcaccga aatccaacat aggatctcag
    18781 tgcttttaaa tagtaaaaat tatttaacag ttacagatgc gccaacttct tcaagtttag
    18841 ctttcaattc ttcagcttct tctttagata cgccttcttt aactggtgca ggagcgccat
    18901 caactacagc tttagcttct ttcaagccta aaccagttgc ttcacgaact gctttgataa
    18961 ctttaacttt ttggtctcca gctgcagtta attctacagt gaattctgtt tgttcttcag
    19021 cagcagcagc gccaccagca gcagctacag ctacaggagc agcagcagat acgccaaatt
    19081 cttcttcaat agctttaact aggtcgttaa gttctaggat agttgcttct tttaactcag
    19141 caacgatgtt ttcaatgttc aatgccatta taatttcctc cgtttaattg ttctttttta
    19201 tttaatgctt tatgcggcaa ttaagctgca tctccatctt ctttgtctgc cactgctttg
    19261 acagcgtaag ccacgttgcg gactggcgct tgtagtacag atagcaacat agatagaagt
    19321 ccttcgcgat ttggcaattt tgccaatgct gtgatttctt ccaatgaaga gactttacct
    19381 tcgatgatac cgcctttgat ttctaatgct tttgcttctt tagcaaattc gtccatgatt
    19441 ttcgctggtg cgactacatc ttcgttactg aatgcaacag ctgtaggtcc agtgaatact
    19501 tcgtccatgc cttcaaggcc agctttttta gctgcacgtg aaagaataga atttttgata
    19561 actttcattt ctacgttagc atcacgaagt tgtttacgta aacgtgttac ttcatcaact
    19621 gttaatccgc ggtagtcaac gactactact gatgcagctg ctgtaaattt ttcgcttact
    19681 tcatcaacga ttgctgcttt ttttgcgata attgcttcac tcatttttga gtttcacctc
    19741 ctgaattttg atggaagagt tttttgcact gaaaaggcaa gtcactttta tagttacttt
    19801 gctcaaccag tattattcat cacctattca cttcgttcat agtgattcta ctcgctttgc
    19861 tcgaaaggaa actcctttcg ctttgctcaa ccagtattgt tcatcatctc ttcacttcgt
    19921 tcatagtgat tcacaataaa aaactctatg ccaccgcaga catagaggga ctattgaata
    19981 tattcaataa acgtcctcgg taggaaatta aggcttgatg ccacctactg tcttcggtac
    20041 aagttaatta ttaacctcaa ctagcttagc atgctaaact agttgagtca agaattattt
    20101 ttcagttgga tcaatcaaca ttctaatatt taattagaaa gaagcttggt caacatggat
    20161 accaggtcca aatgttgttg tgatcgttac atttttcatg tattgacctt tagctgctga
    20221 tggtttagct tttagcaata catcatggat tgctgcaaag ttttcaacta atttttcatc
    20281 gtcaaatgaa acttttccga ttggtacatg gatatttcca gctttgtcca cacggtaagt
    20341 tactttacca gctttcactt cgtttactgc ttttgttacg tccattgtaa ctgtaccagt
    20401 tttagggttt ggcattaagc cttttggtcc taatactcgt cctagacgac ctacagtagc
    20461 catcatatca ggtgttgcaa caactacatc aaagtcaaac catccgtttt ggattttttg
    20521 aaccatgtcg tcgtcaccta cgaaatctgc accagctgct tcagcttctt ttgctttgtc
    20581 tcctttagca aaaactaaaa cagtttgtgt tttaccagtt ccgtttggta atacaacagc
    20641 accacggatt tgttggtctg cttttttagg gtctacgttc aaacggtatg caacttcaac
    20701 tgttgcatca aattttgcaa tgtttgtttc ttttgctaaa gctactgctt cggcaacagg
    20761 ataaacttta cttgaatcaa ctttttttaa tgcatcttgc atttttttgc tctttttagc
    20821 cattttggtt cctccttgat tgtggttata acggttgtac ctcccacgtg ttctatatct
    20881 ttcaatatag agccaactga gaagctgctg tcttagggtg tatagattat tctacagtga
    20941 tccccatgct tcgtgcagtt ccttcaacca tgcgcattgc tgcttcaacg ttagctgcgt
    21001 ttaggtcttc catttttaat tcagcgattt ctcttacttg atcgctagaa actttcgcaa
    21061 ctttattttt gtttggttcg cctgaacctt tttcgatttt agctgctttt ttcaatagaa
    21121 cagcagctgg cggtgttttt gtaacgaatg tgaatgaacg gtcttcgtat acagaaataa
    21181 caaccggaat gatcaaacct gcttgatcag ctgtacgagc gttgaattct tttgtgaatc
    21241 ccatgatatt gatacccgct tgacctagtg caggacctac tggtggagct ggagttgctt
    21301 tacctgcagg aatttgcaat ttaacgattt tttctacttt ctttgccacg agacatacct
    21361 ccttaagtcc gtgatgtggt taattggaga tgcatatttc tcctcccacg ttttatctga
    21421 tctgaaaaaa tccagacaaa taatgtgcaa aacaatgcac actggtacag tatagcaaat
    21481 ttatttgttt tttcaagatt tttttctgct atttttacat tttgcttgaa taaacgctaa
    21541 atttattcta aaaaaacaac aatttttcgt tctcatttct tcttttatgt tacacttgcg
    21601 ctagcatggt tcaacagatg aaagcaaaca ataacacggt tttttagacc cttgtacaaa
    21661 gattcctaca taacaaaatg aggtggagaa aatgaaagat ttaaggtata gaagtgtctt
    21721 tgatattatt ggacctgtga tgattggtcc aagtagctct cacactgccg gagctgctag
    21781 aatcgggaaa atcatacgta gtatatttgg cgaacagcct gattctgtag atatttatct
    21841 atatgaatca tttgcaaaaa cctatcgggg gcacggaaca gatattgcat tagttggcgg
    21901 cctgttaggg atggaacccg atgatgaacg tttagctgat tctttgaaat tggcatatga
    21961 agccggtatg gaagtcttgt ttgttcctaa gagtgaaaaa gccgaacatc caaactctgt
    22021 aaagatgctt ctaaaaaaag gaacacgaaa gctttcagtc actggcattt cgatcggcgg
    22081 tggcaatatc cagatttctg aattgaatgg attcaaaatt tctttaagca tgggtactcc
    22141 taccttgatc gttgtccacc aagatgttcc aggtatgatt gctaaagtga ctagtatact
    22201 ttctgagacc aatacgaata tcggcactat gacagtgaca cgggaatcaa aaggtgaaaa
    22261 tgccattatg ataattgaag tagatgatcc tcaagtagaa gaaacggtaa aaagactcaa
    22321 acagctgcca aatatcgaca gcgtaaatta tttcgattaa ggagctaaaa aaatgttttt
    22381 atcgattgaa gaattagtag atcaagcaaa agcttatcca agtgtagcag aattgatgat
    22441 tgcagttgaa atggaaatga gtggccgttc ccgtagtcac atcatcgaga tcatggaaaa
    22501 aaacctctca gtaatggaac aatcaatcaa cgagggaaaa gaaggtgtta cctccgtcac
    22561 aggaattacc ggtggtgatg caaaaaaatt agatgattat ttaaatgagg cagacttttt
    22621 aagtggagaa acaatcttaa aagctgtacg caatgctgta gctgttaatg aagtcaatgc
    22681 aaaaatgggg ttgatttgtg ctacaccgac tgccggaagc gcgggtgttg ttcctggtgt
    22741 gctgatggct gtccgagatc ggcttgattt gacacatgaa cagcaattgg aattcttatt
    22801 taccgctggc gctttcgggt tagtcatcgc aaacaacgct tctatcagtg gtgcagaagg
    22861 gggatgtcaa gcagaagttg gttctgcaag tgcaatggca gcagcagctt tggtttgtgc
    22921 aaaaaatggg actcctcatc aagcagcaca agcagtagcc attacattga aaaatatgat
    22981 gggactgatt tgcgatcccg ttgcaggctt agttgaagtc ccgtgtgtca aacgtaatgc
    23041 tttaggctct tctcaagctt ttatctctgc tgatatggca ttagcgggta tcgaaagtgt
    23101 cattccgccg gatgaagtcg ttgctgcaat gtaccaagtc ggacgtcaaa tgccgtcgat
    23161 tttcaaagaa acagcagaag gtggcttagc tgttacgcca actgctaaac gacttgcgga
    23221 agagatttta aataagaggg cgtgataaag ctccttaatt tcgagtatta agagattagt
    23281 tatcttcata acaaaaaacg aagagaggac taattgccct tctcttcgtt ttttattaat
    23341 ccatcaattt cgtatttttt acttcatcga tcgtttttgt tcctgcaagt tgcatcgtga
    23401 tcgacaattc tttgttcagg tgttcaaaaa cagatgttac tccttctgcc ccacctagat
    23461 tcaacccata aatcactggt cggccaatcg caactaagtc agcaccactt gccagagctt
    23521 tgaagacatg ctctcctcga cggacaccag agtcgaaaat cactggtaca cgtttgttga
    23581 ctacttcggc aatttttggc aatacttcaa aggacgcagg acctccatct agttgacgtc
    23641 caccatgatt ggatacccag ataccatctg cccctgcaga gatagcgatt actgcatctt
    23701 ctggcgattg tattcctttt acgataactg gaagatgggt gatttctttg attgttttga
    23761 tgtcatctgg tgtcaagcct tgttttgcag ctgcataaat ttctgcgatt ccttttcctt
    23821 cgccattacc acttgcactt tgttcgctat acgcagctaa gttaggcatt ggtaatggaa
    23881 attggaattg attgatgacg tcttcttcac ggtaaccacc gagcgttgaa tctgccgtta
    23941 aaatgatagc tttagcccct gcttctactg ctttgttcaa aatgaactca ttgaatctgt
    24001 cgtctttact catatataat tggaaaaact gcggtgcgcc tggcgctgca tcggctgcgt
    24061 ctttgattgt cgtatttgca taagtgctga tggaaaagat tgatccagca gcagctactc
    24121 ctttagctgt atcagcttcc cctttttcat gtgccaatcc ttgggccgct gatggcgctt
    24181 ggataatcgg tgtatctaat tcaattccga aaacagatgt atgcaaatcg gctgagtcga
    24241 ttccgcgtaa tatccgtggc atgattttct ttgtattaaa agaagtcgta ttttctttca
    24301 tcgtccactc atcttcagaa ccaccgcgaa tatagccaaa agctcctgct tccatgcgct
    24361 cttttacacg accttctagt taggcaatgt ttacaatatc gattggatgt tcttcattac
    24421 ttgtatgata agtcatagta gatccttctt tcatcttctt gattacatat aaatcatact
    24481 aaacttacaa aaagtaagca aacatttact ctcagatact tttatcgcta ttctttccaa
    24541 ataaatcgac ttacaagctg atctacttct tggttttcat gaagcatact atgagaggca
    24601 ttttcacctg tcactacttt ttcctctatt tcatttccgc gttgcttcaa caacgcatag
    24661 accgctaatg cactgtttaa cggtactgtt ccatcactca agtctgtttc atctagttga
    24721 ccagcaatca agaaaaatcg agtggttata ggaatattac cgatcatttg ctggtaatct
    24781 tgatagcggt tagaaacgac agcaggcccc tttgctaact catctgtcag agactgcgca
    24841 ctatcatcga caaaatcatt aaaaggcgcg ccaattgctg ttaatgtctg aacttgtggc
    24901 aatgacgtat cctgtccata cgttcctaaa tagcgtagtg cactaactcc tcccatggaa
    24961 tgccccacta tgttgacttt atctatgccg tagttttctt tcagatacaa aagacaagtt
    25021 ttgatccatt ctgcttgatt ccactcgtta tttttattat cttcaaacaa tacttggacc
    25081 atcggattgt ctgcttttcc agacaaatct cctgttgctt gtatttgtcc atctgttcct
    25141 actgttaaaa ccaattcttt tactgcttgc tgattttttt ccaaacgccg caacatccct
    25201 ttaaaggaat tttctgtccc gctgtagccg tggaaaaaaa gtgttggaat agtggttttt
    25261 tctatcactt tactggattc tgccgttttt tctttatcag aaacttcagt agtatttatc
    25321 ttcgtcgtct ggcaaccact taacgcaaac aaactgataa ggactaaagc tgctgcagtt
    25381 gcacgtttgc ataaattttt gattggttct gtcatacacc tcttcctttc catatagaaa
    25441 aaagaaagac ttgaaaggcc aatcatatga tcgacatttc aagtctcttt attaatcgat
    25501 tttatctact tgatcgaaat caagttctgt actggtttca cgtccaaaca tatcgatgtt
    25561 gactttcaat ttttcttttt ctccgtcaac ttctgttact tgtccttcta atccagcaaa
    25621 tgcgccttcg atgattttca cgacttcgcc aacttctact tctagatcat tttgtcgcag
    25681 gctcataccg atagaacgca agatatgatt gacttcttct ggaagtaatg gtgctggttt
    25741 gcttccggct ccgtgtgaac caacgaatcc tgtcacacca ggtgtgttgc ggacaacata
    25801 ccatgaagcg tctgtcatga tcatttcaac aagtacgtat cctgggaatg ttttatgaac
    25861 gatttctttt tctttcccat ttttgacttc agtttctttt tcttcaggaa caacgacacg
    25921 gaaaataaag tcggccattt tcatactttg cgcacgagat tcgatatttg cttttacttt
    25981 gttttcatat cctgaatatg tatgcaagac ataccagttt ttttcaaaag attccattga
    26041 aggctcctca tttcattgta aaataaaaaa acctcagtac acccgaagtt tttctttcgc
    26101 ttcattatag cactaaaagt acgttgtggc tagcgagtta ttttaaaatc cagccaaata
    26161 agctttggat ggctgtatcc attacgtaaa acatcaatcc gaaaataata gaagtttcga
    26221 tgactactaa cgtatcttta cggagttgtt ttctgcttgg ccaagttact tgtttgattt
    26281 catcttttac gctttttaga aatttcatga gacaacctcc cttgctactg tttatttcgt
    26341 ttctttatgt aatgtatatt gattacaata tttacaaaac ttattgattt ccaaacgttc
    26401 gccgcttttt ccttcactga ctgattttgt gtagttgcga gacccacaaa cggaacaagc
    26461 gagtgctgct tttttctttg ccatttactt ctgccccctt gctgagaatc agacttatac
    26521 ttcataacag tatcacgtaa ctttttactt gtcaatttgt gaaataaact atctattgtt
    26581 ttggataaaa ttatgatatg attaatttga aattaagcta aaatgagaca attggaggta
    26641 tagcgatgct attaaaaaca cttgtatata agaaaaaaga tctgacaacc gttacagaga
    26701 ctagtacatt agaagaagca ttaaaaattt tagaaacttc cggataccgt tgtgtgccga
    26761 tcttagattc ttcaggtaat attttccgtg gaaacattta caaaatgcat atctatcgtc
    26821 ataaagcaaa tggcggtgat atgacgcttc ctgtcactca tcttttgaaa aacgctacaa
    26881 agttcattta cctggatact tctttcttca aagtattctt tacgatcaaa gagcttcctt
    26941 atattgctgt ccttgacagt gaaaatcatt tttatggtat tttgacacat agtacgttgc
    27001 ttaatatgct ctctcaatct tggagcgtag aacaaggaag ctatgtactg acaattgctt
    27061 ccacaggaaa gcaaggagat ttggctgcta ttgcaaaaat catttcaaaa cacagcagca
    27121 ttgccagctg tattactctt gatatcgaaa aagacgaata cattcgacgt acattgatca
    27181 cgctaccggc taacactgaa gcgaaagtat gtgaaacgat cgtcaaccac ttagagaaaa
    27241 agaattataa agtggtagaa attgaaaatt tgcaaaacca agaagcataa tcaaaaagcg
    27301 aaaaaagaaa acagctaatc tgctttcttt tttcgctttt tataattaga cacgcttttc
    27361 aaaatcaagc gcgcgatcta aataatacat caatggtgct gaaacagcca tgacgataaa
    27421 ctcacttaat gcaagcgtgc cataggttgt ccaaaatgct tggccacctg ttggaactaa
    27481 catataagca atcagtccca tgctgatggt aaagaagatc gtgttcaata ctaaacgcat
    27541 ctttacattt ttcactttgt tttgcaataa agctgtcagg cctaaagaaa gcaatgtttg
    27601 gccgccacca aaaaccacat ccatgatacc aaaaccaaag aaggcattat agacgatgac
    27661 cccgcctaaa actccccaaa gcaatttacg gttaaagaca actaaatgat tcaaactttc
    27721 tgaaatacga aactggatcg gccctgagga tacaggcgca actaaaatag ttaacgctag
    27781 ataaagagcc atgatgatgc catttacaac gattacggat aaccgttgtc tgcttttcgt
    27841 tttttgcatt ttctctcctc ttttctccta gtttttttaa cgcgggatgg ttgatgaacc
    27901 gcggttatgt gaaacaaaca ataattataa cagacttttc atttatttca atccgtctta
    27961 tctgctttta aaaaagcaaa agcttaaaca atgtaaacgt ttgctaaaaa tcgtgggata
    28021 tggtataaag taagtgtaag gggtcataag aattcccagt aaagcagacg aagtaggatc
    28081 tgcaagaaca gaattgttgt gaaacttaaa taaataaaaa aggatgtggg aatttgagca
    28141 acctcttact agagaacggt ctagcaagca gctgaagatc taagtggaca tgccgaacct
    28201 tggaacttct ccttacgtaa gtaatggatc atgcgcttgc taggcttttt tgtgtttttc
    28261 ggtcttcgga cctttttcat tttcctagac ttctgctata ataaccaaga attaattttg
    28321 taacagattt ttttgaaaaa acaagtttct ttcattcaaa aaatagaaaa agcttgctaa
    28381 ttattggtta accagcaaac aggagtatta aaatatcttg ttttattgaa tagcaggagg
    28441 aaatcatgaa attccattat catatattga tcaatccatc ggcaggcagc ggaaatggct
    28501 ataaagtagc agaaagaatt ttaccggtat taaaaaataa gcatattgac tatacacttc
    28561 attatagtga atacaaagga cacgatgctg agattgctga aactttggca aaagaaacat
    28621 tgattccttg gatagaagaa gaacagaaaa caatcgatac tttccccctt ttgatcatcg
    28681 taggaggtga cggcacctta catcaggtac ttgatacttt ctatcagatg gaagtagaat
    28741 tcccagttgc ttatattcca gcaggttctg gagatgattt tgctcgaggg gcaggccttc
    28801 caaaaaatcc caaaaaagga cttcagctga ttttagcagc tcaatcacca gaaaaagtcc
    28861 acataatggc ttatgaagaa aaaataagtg aaaaaaaagg aatagctgtt aataatttcg
    28921 gtataggatt agatgcagct atcgtccatg cgacaaatca ttcttccaca aaaaagcgat
    28981 tgaacaaata caacttagga tcattttcgt atttattctc tattctccgt gctttattca
    29041 ctcaaaaagg atttccaatt ctggtagatg caggaggaaa acaattaagt ttttcaaacg
    29101 catttttatg tacagcaacg aagcatcctt tttttggcgg aggaatcgcg attgttccaa
    29161 ctgctgatgc gtctaaacca gtcattgatt ttgtcgtggt cgaacgaatc aatttcttta
    29221 aaatcttgtg gctcattctt ttacttatac agaaaaaaca attgaaatcg aaatatttcc
    29281 atcactacac aacaaacaga ttacgtatcg tttcaacaac accgcaacat ggtcaagaag
    29341 atggagaaga aatggaaaaa cgaccttttg atatcacaat aaccacaact aaacagttgt
    29401 tttggtgtta ataaaagagg ttttgtcaga agctacatct ggaacaccgt ttattcggaa
    29461 aaaaggactg tgacacgact tttgtcacag tccttttttt actatgcagt taattctttg
    29521 cccaattggg ttgccatcga tagtttcttt ctttacccaa aataaattgg atcattgaaa
    29581 acaccgcagc aaaagcaact aagacacaac cattgaacca aaaagattct gcaaatgttt
    29641 gattgtaact gagtgtttca ctgatcaagt tattattttg aacaaaccaa tatgttggtg
    29701 tgaatgccgc tattttgcta accatttctg gcaagtattc tgctggtaca aacaccccac
    29761 cgataaagca actgcctgtg ataaaaatat ctttgatccc accgctggtt tctgagtttt
    29821 ttaccaatga agtgatacaa gccgaaaagc taatgatcgg caataaaaac aagaaagtat
    29881 ttaaaatatg ataccatacc gttatatccc acgaggtgtg gatcactaac agaaccatta
    29941 gaagtaagaa gccactgaac aacagcagcg agtaactaat caaactaaag gttactttgc
    30001 gattcaagtt tcgtttggta atgggcgcac tctggtttcg tttactgatc tctttgcgat
    30061 taaatgctag attgatgacg ctgaaaccgc taaaaatgga tagaaacaac ccataagaca
    30121 agaaattaaa ggttgtgccc gtcaacagct ttttcatccg ctgactatat cccgcactta
    30181 gctcaacttc tccagtaacc gagagtgcca tttgtgtctg ttccatagct gcatcgattg
    30241 ttttatcttc ttcttgaaac agaatcagtg tttgcaaaaa ggtgttcact tgctgtgtaa
    30301 caactgtttt agaaaaggca tctgggcgac tctgtatctt gatcgtcggc atctttccta
    30361 cttcgacttg ttcggtaaag tctgcaggca gatgtaagat aatgtttaca cgattaaaat
    30421 aaagagcatc atcgatttct ttttgtgagg ttccatccaa tgtaacgact gtttccttgt
    30481 cattcaaata tttacgaagg ccatcgacta caggcgactc ttcttcacta atcaaggcga
    30541 ttttcgcatc ttgcagagag gtattttcaa catcaatatt ttgcgcaaaa aagaatgtgg
    30601 caacaacagt gataattaca cctatcagta aattcgattt atttgcttta agcaatgtcc
    30661 aaatcgtttt ataaagcgtc ataacgcacc cctctttcca tccaagcatt tcctaacgca
    30721 aaaaggaaaa taaatccgat caaccataga agattggtat aaaaactagc caaatcagtg
    30781 tagaaataaa gtttatacaa actttcgctg atcaagttga cgagatttaa ttgaccaaca
    30841 atcggaatat gaagatcaat ccaatacttc acttgttccg accccatcat accagcaaaa
    30901 aagctcatcg caatcgtcac tgaaatcaag atgctatcct tttgcaccag attcattttt
    30961 ggtatcaaat taccaaccaa tgtacctaac aaaatcgcac acaacgaccc cagagcggta
    31021 acaatcatca accattgcca acgttcacca aagtctactt gatagataaa acgaaagaca
    31081 gctaacataa tataaatctc tgtcaaaaca atcgtaaagc ttgctgccaa attagcgatt
    31141 gaaactaacg attgctttct aggaatcaag gacaagcgaa taccatttga cgattgattt
    31201 gcttgctgat cctgtacatt gcggaccccc cacatcgtcc cgtagagaat cgccattcca
    31261 atcagagtga agaaataaaa acttttgaaa ctcatattac gacctgcatg aacttcttga
    31321 aaagatactt cttgttcaaa aacagtcatg atgggcgcga gatcaacgtt ctccacttct
    31381 gccactttac tcgaaattat accaatacgc tgtaaaaatt gatccatgac gtttttcatc
    31441 aacgtctgac tcattcctgc ttgacccaca tggagcgaaa cagatgaacc atcaatgaga
    31501 taaaaaccag ccaaatcatc tgcatttagc ttttcattcg cttctacttc cgatagttcc
    31561 tgtacttcaa ataatggttt atcattgact tcgacttgtt ctaagactgt ggtaaaattt
    31621 tccgaaagcg ctgtttgatc cgctttgatt acaattccag tattaatcgt ttcgagattg
    31681 ccaccttgat caatctcgcc aaaggccgcc ataaacatca atcctaaaag aattggaaag
    31741 gccaatgtcc aaaacaacat ggatttattt cgcagcagta tttttgtgcg atatttataa
    31801 aaatgccaaa acattatttc ccctcctcta gtctctcaaa tccttgccag taatctctaa
    31861 aaagacatca ttcaaggacg cttctttggt tgctattttt ccgtaactga tcttttcttc
    31921 ttgtaagatt gtaagaatcg gcaacaatac tgtatttagt tcagtagttg ttacttggag
    31981 ctgacctttt ttataagcga ttccatcaga agctattgtt cgctgacaac acgttttctg
    32041 ggagtaatgg gatgtcgatc gtcaaacgat ccgccgtccg taccatatct tttagagatt
    32101 ctttggttcc tttagcaatc acctgtcctt gatccatgat cacgatctgg tcgcaaagaa
    32161 tttctacttc ttccatgtaa tgtgttgtat agacaatggt tgctccttgt cgattcagct
    32221 ccttgatact ttctaaaatt ttattccgac tttgggggtc tacagctact gtcggctcat
    32281 ctaaaaaaat taaccgcggc ttgtgggcaa tcccacatgc gatgttcaac cgacgtttca
    32341 agccaccact aagttctcct ggacgaaacg aaacatattt ttctaatccc actaattgaa
    32401 tcacctcttc aatcaaggct ttccttttct ctttttcgga aacatataaa ccgcaaaaat
    32461 aatcgatatt ttcttgcaca cttagttcgt caaagaccgc aacgtcttga ggaacgaccc
    32521 caatcattgc cttgacagca taattttcag gagtcattgt tgtcccgaac aatttaatgg
    32581 ttcctttgtc ataatttaac aaagaaagca tacagttgat ggcagtcgat ttcccactgc
    32641 cgtttggtcc taacagacct aagacttctc cttcttgtac ttgcagatca aaatgattca
    32701 atgctacaaa atctccatag cgtttgacta atttatcaat ttcgataatc atcatgaaaa
    32761 actccttcca aatttcttgt tgatctgact ataataaagt gcaagaaaag aaactagtga
    32821 cgattggcta aaccacacat gacatttgtc acaatgaagg agtctgctat gcataaatct
    32881 cggctactca acgaaactag ctttctactg gttatctcat tgcttttgct ggtaagtcaa
    32941 ggattcgttg ctatgcaagt tatctattta ttgatcgccg ttttattcac tggtgtcagt
    33001 tatttactgc ctacaaagcc aaattggatt ttccaagtta ttctatttct tttatgtgcc
    33061 tttttacctg atcttgtcct gtttctgcca gcgacgatgc gagtgatcgc ccctgaagaa
    33121 agccaccttg attacttgtt tttgttaggt tttttgttga tttcgacggt tggtaatcat
    33181 ccccccatca aggtcgcctt tgtcgtaatt ttgctgtttt tttcctttta cttacgaaaa
    33241 aaagatcaac gaacgaccga tcttgagaaa aagtacattg tctccaaaga tactcattgg
    33301 gaaaaacaac aagagttatc ggaacaaaat aaagcattgg ccctgtcaca agaaacacaa
    33361 ttagccttgc aaattgtgga agaacggaac cgaattgccc gagacatcca tgacaatgtc
    33421 ggtcatctgc tgtcaagtgc gattttacaa attggtgcgc ttgaaatgat caatcaagaa
    33481 ccaaaactaa aagaaccatt agaaaattta agtgccaccg ttcacactgg gatggatcgg
    33541 attcgtcaaa gtgtccatga cctccatgag acatcgatct cttttcaaca ctccttagag
    33601 tttctgatcg ctgattttcc ttcttctgtt acgattgaag gaaacttgtt tgaaggattg
    33661 aatgaaacgc agcaaaactg cttcttaatg gtcatcaaag aagccttaac caacagtatc
    33721 aaacatagtc atgccaaaac cgttgtttta cattttcgaa cgttgccggc cttttatcgc
    33781 ttgcaaatca cgaatgatgg caccagccca caaaaaaatt ctgctcccgg tattggtttg
    33841 aaaacgatgc gtcaacgtgt tcaagaacaa aagggacaag tccatatttt ccaagaaaac
    33901 cagcaatttc agttaacgat cattttacca agggagggac accaatgata acagtagtca
    33961 ttattgagat gatccatttg tgacgaaatc gttacaaacc attttagaaa gcacgaaaga
    34021 gatccgtgtg ttaggcattg gtcattgtgc caaggatgcg ctagtcttat acgaaaccca
    34081 tcgtcccgat gttttgctga cggacatccg catgcctaaa caaacgggca tcgatgctgc
    34141 caaagaaatt ttggctaaat ttcccaaagc catccttttg cttttgacga cattcaaaga
    34201 tgaagaatac atccgcgaag cattttccat cggtgtcaaa gggtatttaa tcaaacagaa
    34261 cttgcaagcg attattcctt ctgtcaaatc cgcttataat ggacaggccg tatttggtaa
    34321 tgaaatcatc gagactttca ctcaaatgat gaagaataaa ccgacgattg atagtcatgc
    34381 ttatgcttct tttagtgaac gtgagcttgc aatcatcaaa gaagtagctg ccgggaaaaa
    34441 caataaagaa attgcagatg ccttgtactt gagtgacggc actgttcgca attacatcag
    34501 ccaattacta gaaaagctag atttacggga tcgcacgcaa ttggctatct atttttatca
    34561 gcatttgcaa taagtcttat ctaacacaaa aaaacctgaa tgatgctcct tcgcatcatt
    34621 caggtttttt tcacatcttc tattcaattg tcccgcaaac catttcctca cgattgaaag
    34681 aatcaaggat tcgcagggct gccaggattc gttggattgt tcggcgtgtt aggcggaaaa
    34741 ataggcgcct tgtctaacgt tttttctagt tttgattctt cacgatcgtc tcgttctaca
    34801 tcaggacttt cattcaattt gaattctttt tccatctcat ctaacttttt aaagtcattg
    34861 ccagattctt ttgctaattt cgctaattta tcttcggttt ctttagccat aaagtaacgc
    34921 cccccttttg atttcagctt agcatatcac actgaaaaaa caaaagaaaa cgctaaccaa
    34981 cgatcatttt tagctatttc tcatctttaa aatcaagcat tttttgccgg tataaaatcg
    35041 tagggagaac tgttttccat accaatcatc ggatctacta actggttatc gatcacttct
    35101 gctgtaagaa cgaaatcttt agaaacagca ggttctacct cttctttctt ttcttctcca
    35161 acaaatgaag aaaacagatc tggttccact gtttccatta cttggttttt cgtttcattc
    35221 gtcccactgt catcttctac aggtagcttt tcttttacaa cccgtggctc ttttgtatag
    35281 ttcccatctt caaatggatc atttccgacc aaagaatctt cataagctgc tagtttggtc
    35341 cggagagtga tattcatttt atcattatcc atgatccttg atttcaacgt agtcatccgg
    35401 cttgctgatt cattcgctac acaagtgaca taggcttgct cttcccctaa caaaatcaac
    35461 agttccttac tgcgagtcac tgccgtgtag agcaaattac gctgaagcat ccgctgatat
    35521 tgatggacca tgggcaaaat aaccatcttg aattcactgc cttgtgattt atggattgag
    35581 caacaataag aaagagtgat tttattccat tcgtttcttt tataagtgac ctcatttgca
    35641 tcaaactgga taactaattc atccacttta tcttcagaat cttttgccaa gatgataccc
    35701 gtgatttctc ccatatctcc attgaataca ttcaattcgg gagtattgac taattggagg
    35761 actttgtctc ctatccgata aacggtgtcg ttccaatgta cttccttttt tccaggtttc
    35821 cctggattga atatctcctg catcatttta tttaacgcat cgatccctgc aggtccccga
    35881 tacattggtg ctaatacttg gatatcttgt gcacggaatc ccttattttt cgctttttcc
    35941 acaattttag agatcaaggg ttcaatttga taagcatcac ttcggaaata ggaacgatct
    36001 ttttgattct ttgtgaaatc ttttggcaga cgtccttctt tgatctcatg ggcaagagga
    36061 ataatactag aaccatcacc ttgccgataa atctgattga gttccatttt gggaatttgt
    36121 tcgatttcca aaagatcatg gagtacttga ccaggaccga cagagggaag ctgatctttg
    36181 tctcctacta agataacttg catattcgtc ggaatcgctt tgaataatgt gttagccagc
    36241 catgtatcga ccatagacat ctcatcaaca atcaaaagtc cgccttctaa ttctttcgta
    36301 ctgactgaag gtgttttttc ccgtccattc agccccagaa gacgatggat cgtactggca
    36361 ggcagacctg tcgtttcgtt cattcgttta gctgctcggc cagttggtgc tgcaagtaga
    36421 ataggaaaaa tttcttgggt atattttgaa ggatccaatt ccagtccgtt caactctgca
    36481 aaaagattga cgattccgtt gatcacagta gttttccccg tacctggtcc tcctgttaaa
    36541 ataaatagag gggaacggat tgcttcagcg atagcttgtt cttgcgaagg tccatactgt
    36601 atgccgaata ttttttcgat acgccgaata ttcttctgca cttctttttc aggataatgg
    36661 atttcttttt tacgactgag aaggcgctgg atcgaattac cgatccccca ttcagaaaag
    36721 tacaaactgt tttcgtaaag attagtctct tcttgttgta tctttccttc ttcaacaagt
    36781 tggataatta cagtagcaac ctgatcaggc tggatttcaa ttgggcgact tgtttctaaa
    36841 atacggatcg tttgctgaag caatgtctcc gccggtacgt atgtatctcc tgtttgaact
    36901 gcatgctgaa aaatctgatg caagatagct gctcgaattc ttctcggtga atctgctgca
    36961 ataccgattt gttcggctag attatctgca cgtttgaacc cgattccttc tatgtcttcg
    37021 actagctggt acggattttc ttcgatgata tccaaagact cgttcttata ggcctggtag
    37081 atactgaaag ctaactgact accgaacccg taacgattca gtcccatgat cacttgatcc
    37141 atcccgtggt ttagccgaat cgtctcagca agcatttctc tttttggctt cgtcaaaccg
    37201 gagatttgtt ttaataccga aggatcagca atgatttttt cgatagcatc ttctcccagc
    37261 aattctacaa ttttttctgc tgttttcttc ccgattcctg ggaatttttc gctggaaaga
    37321 tacgctacga tcccatttgc agttgttggc ttttcttgct catatctttc gagtttaagc
    37381 tgccttccgt atttaggatg atccactaat tctccataaa aacgataagt ctcattttct
    37441 tgaatatcgc cgaaacttcc ggtgactaca atctcttttt cacggtaatc agctgtggtt
    37501 tcactgatgt gtaccaaaag cactttgtaa aaattactag gattttgaaa aaaaatcgcg
    37561 gcaactgtac caacgaaata aggcatttct tctggctgca tcggaagccg cctccttctt
    37621 ctatagtaaa ggttctggtg ctgtttcagt tcctaaaaaa tctgtttggt tccatacttt
    37681 cagttcatat ggcaataatc tgcaaggctc ttcagtctct aaaatcgtca aactactatt
    37741 gaacaatcca cccatttcac gcaactcact tagctctttt cctgtcatcc attgaatggc
    37801 tgcagttaaa gaagctccat gtcctacgaa taaaagtggg ccatctttat gttgggcaac
    37861 cgcatctgct acaacagttt cgatacgtgt gattgccgat tcaatcgttt ctccgtgaaa
    37921 aggagaagga tcatacagat ctaaatgatt acgcaaattc ggcagattat ccggatattt
    37981 ctggtacatt tcatcgatcg actgaccttc taaagtaccc agccctagtt ctcttagctt
    38041 atctgtataa aaaatctcta ccggacgagc aagctctttg ttgatacctt ctgctgtatc
    38101 acgtgctcgc tttgctgtac tggaataaat tgctttaaaa ggaacatatt ttaccttttt
    38161 cccaaatgct ttgatttctt cgtaactttg tggcaaaagc ggagaatcgc cattgctccc
    38221 ttgaaaacgt ctttcctgat tccattgtgt cttcccatgt cgggtaaaat atagttccat
    38281 acgcagcaaa ctcctgtctt tcttttattt tactctataa taaactgtct aatccagctt
    38341 gtcattttca tagtgatgcg tcaattctaa attagggaat ccttgctggc gaagtgcttc
    38401 atacactatc attgcagctg tattcgataa attcaatgag cggacatgct catcattcat
    38461 agggatgcgt aaacactttt cttcgttttc acgcataaat gtttctggca aaccggttgt
    38521 ttcttttcca aataaaaaga agtgctcttc tccatcagca aaattttcgt cactatatac
    38581 tttatgggca aattttgaga tcaaatgtag tttacgatta cctaaaaatg ttaaaaaagc
    38641 ttctaaatta ctgtggtaag taatatttac atcattccaa taatccaacc ctgcccgttt
    38701 tagatgtttg tcatcagttg aaaaacctag tggctcgatt aaatgaagcg gagtattcgt
    38761 ggctgcacac gtacgggcaa tatttccagt gtttgcaggg attaatggtt caaataaaac
    38821 gatatgattc atcaggatca ttcctctcat atttatgttc gtttctattt tctgacaatt
    38881 tgatttttgc ataaaaaaaa acgtatcaac tcggtgtcag tcactgcgag tcgttacgtt
    38941 agtgaagctc ttctcactaa cttttatcag aacaggaacc tgataaaaac caatgaaaaa
    39001 acaacttgtt gctaatataa caccctcaac ttttttttgc aacctctact cattaaaaac
    39061 tgctagaaaa acgttttctc ttagttcctt ttaataattc tatgtcaatt gtaatcttct
    39121 tcaaaggatt cttatataag tctgctttga ttcgctcttc tacctgccat tctaaaggtg
    39181 acatggccaa aagatctttt tgattttcct ctggtatctc aaattcatag gttacacgct
    39241 gacgttcagt taatttcatt gcttcagcaa acttggctac tacacgttca ttggaataac
    39301 tctgtttttc aggttgattc ggataaaaag cctgacgtag ttcctttaaa taattttctt
    39361 gtggcaccac cttcaacact tctccatctt ctgagagtac acgttggaat tcttggtaat
    39421 gagaaggcga aaagatattt aaaaccgcgt tgaatgtttg atcagcaaac ggcaaattgg
    39481 tcaaatcagc tacacaccaa aatgcttcgg cagattgttc tgtagctgcg tagactcctt
    39541 cttttgaaat atcaaatcca acagcatttt gaatcttttt caattttgaa agttcattca
    39601 agaagctacc ttctccgcag ccaacatcta atagcgagac ttcttcaggt aaatgctgcg
    39661 caatagtctc aataacgggc tgatacatgc cagattggat cattctacgc cttggaacga
    39721 acattccttg atcgtattct gttttaaccg catgggataa aaaataaagt gttccttttt
    39781 tggaaaggtc aaaacggtga ttatttttgc atatcaagcc attatcagac ttttttactt
    39841 cttcttggca aaccggacag cggaacagct gatgattttc tgccaaaaac tggcgtcctc
    39901 ggtcaatttt ttttaacata gttccccctc atttctgttt tatcttaccg ttagatgctc
    39961 actttggcaa ctgctaaaaa tatgatacaa tgcctagaag aaagtgaaag ataaaggaga
    40021 agattagatg atcaaagaat tttgcgctga aaactacaca tctattcctc tagcaattgc
    40081 tagaggagcc gatcggatcg aattgtgtga caacttagcg gtcggtggca caaccccgag
    40141 tactggtgtg atcgaagaaa cgttaagtta tgctggggaa aaagatatcc ccgtaatgac
    40201 gattattcgt cctagagggg gcgacttcgt ctataacgat atcgaattga aaatcatgca
    40261 tactgatttg attgaagcaa agaaattagg gacggatggc gtagtatttg gttgtcttac
    40321 tccttcaggc tggctagacg aagaggcctt agaactattg atcgaaacag cagaagggtt
    40381 gcagatcacc ttccatatgg cttttgacag tattcctgaa gatcggcaat tcgaagcaat
    40441 cgattggctg gtagaacatg gtgttgaccg tatcttgact catggcggtc ctgctgacaa
    40501 aactattgta gaaaatttcc cacggcttaa agaattgatt gcctatacag atggccgctt
    40561 aatcattttg cctggtggtg gtgtcactgc agagaatgca gcacatgtag ctaaagaatt
    40621 gaacgtaagc gaagtacacg gaaccaaaat cgtggatctt cagttataat cttataaaca
    40681 aaaaaacatt tgcaacaggc ataatgctta ttgcaaatgt ttttgttttt ttacataaaa
    40741 tagcccataa ataaagaagc aatattgaaa taaatcagta cactcgtcaa atcgctcaaa
    40801 gtcgtgataa agggaccgct tgctactgct ggatcaaatc ctagacgatc cattagcatc
    40861 gggattaaac tacctgcaag attcgccact gtgattgcaa atagcatagc catccctgtg
    40921 acaaacccca agataaaatt atgtttccaa aaacctacga ttagaaaaat cgtgatcccc
    40981 gtaacagctc ctgtgacaac gccggtcaag acttcagcca aaacaagtcg aacaaatcca
    41041 tgatctttct catcagaaat cgcaagtcga cgaacagcca cagctagcga ctgggttcca
    41101 gcattaccgg cagttcctgt aatcagcgaa atgaagactg ctaaaatact cgcttcactt
    41161 accaagtctt catagtgact gattaaagaa gcggtcgaca tacctaaaaa caacagagtg
    41221 atcagccaag gcaaacgtcg agacgctgcc tttactggat tttcattaat ttcttccaca
    41281 ttgaccccgg caagtcctga ataatcgcta gcagcttcat catcaataac gtcgatgata
    41341 tcatcgactg tgacgattcc taacaaatga tcatcataat cggtaacagg aagagctaag
    41401 aagtcataat ctctaaatgt ttgtgccaca tcttcttggt cgtcgcctac atgaactgaa
    41461 agcactcgtt cgctcatcag atcagaaatc attgcgtcgt catcattcac gattaggtcg
    41521 cgcagagaaa taacccctac tagctgacct tcttgattaa cgacatagat gtaatagatt
    41581 gtttcagcta catctgcttc gttcttcagc acgtacatcg cagagcgaac agtttgattg
    41641 gctacgatcg aaacaaattc agttgtcatg atcgcgccag ccgtttcatc ctcgtaatgg
    41701 agaagttcct tgatttcact ggcatcgtct gccgacatca aacttaaata tttagcaatt
    41761 tgctttttat ccagcgtatt aagcaagtca acagcattat ctgtatacat ctcagaaagc
    41821 atatcagctg catagctagg acgcatttca tctaggtatt ctttcatatg ttcgttgtct
    41881 tcttcaatca catcgaacat atccgctaat tctttaggcg acagatagga atagatcagc
    41941 tgcctgttct cttctgtaag agattggtag aattgcccct gctcatagat atgcatctct
    42001 aaaaaactgt ttctgaatgc ctgaatatta ttttccctta aatcttgagt caactgggca
    42061 aatctttcct ctaattcttg attttcatcc aaaccaatct cacctcgcct tattcttcaa
    42121 accgtctcac aactgcctcc atgtctgcgg ctaaaggctg cttgaactcc agcaactctt
    42181 ctgtaaatgg atggtaaaaa cgcagatcat aacaatgaag ggcttgtctt tttattccca
    42241 gatccattcg cccgccatac atatcatcac cgagcagggc acagccaatt gcggaaaaat
    42301 gaactcttat ttgatgtgtc cttcctgtat gcagctggat atcaactaac gcgatttctg
    42361 ttagtcgctt ctctatccag tactcagtct gtgccgaacg tccttcatca gagaccattc
    42421 gcttcaatag cgaagaataa tctcgggcga tcggcaaatc gatatgtcca tgtgccgata
    42481 aatctgaaag ccttccactg actaaggcct gatatttttt cacaaacttc ttttcacgaa
    42541 gttgcatatc taattttgcg tgcgcaaatc catgctttgc aaaaagcatc aaaccagatg
    42601 tatcccgatc tagtcgcgtc accacatgga ttacttggtt ttcgtaacct tgttttttat
    42661 aataagcctt tacacgatta gccattgtcc catttggatg gtattgggca ggaatagacg
    42721 aaacgcctgc tggtttattt actaccagaa cgtgttcatc ttcatacacg atatcgatcg
    42781 gtgtttcatc caaaagtacg gtttcatgtt ctccttcagc aggaatcaca atggttacct
    42841 tatcatcctt agctagagaa aacaagacat tttctacttg atcattaact ttgatttgac
    42901 cgccttgaaa ttttattttc gctaacagac cctttgagat ccctttttct tttaaaaaat
    42961 attttacttg ctgagaatga tctttctcat aatcccatgt aaactgcata tcaatcctca
    43021 ctaataaagg catctttcac acgatgccaa aaatgcatat gtcgataaga agcaaaatgg
    43081 atccgttctt ctgctattcg ataataaatt gagcggatat ttgcttttgc gacattcaat
    43141 tgatcaaccg ttacaagata atcttctgta ttttccaatt ttatttctag ccattcatca
    43201 tgggcaatca cgatcggaga acccaaagta cgaaacactc gattattcag tgaagcaatc
    43261 tctgccaact gaaaggcatt gatactagga tggatcacag caccgccgac acttttatta
    43321 tatgctgtcg aaccagtagg cgtagaaatc gtcaatccat ctcctctaaa actttcaaac
    43381 agctcgtttt tgatgtatac atcggctacc atcgtacgat tggcccgttt aatcgttgat
    43441 tcattcagtg ctaaaaaatg ctggtccggt gtttcatcca aataactgat ccgaacatcc
    43501 agcaagggat aactaacact ttgttcccgg ttcgttcgta agctgtctac tagttcttcc
    43561 agctcgtaat cccgccaatc cgtgtaaaac cctaaatgac ctgtatgcac gcccaagaaa
    43621 cgcacatcat tcagacaatg actgtagtga tggaacgccg acaataatgt gccgtctccg
    43681 ccgactgaga tgaccaattc tggctcatga tcatctcgtt gaatccctgc ttgttctaaa
    43741 agtgcgttca aacgttctgt cacttctata gtctttgctt ctttattatg aacgatcgct
    43801 actttcatcc cctgcctcct ctctttcgct ttctttcttc aaaagcgttc gatagtagac
    43861 atcatctgat tttcctcttc catgggagaa taaccgctgt gcttcttgga tttcttcacg
    43921 gatactggac atctcttcat ccaactgata ggcagcttct gccgcacgct gaagtcgttc
    43981 actcatttct tctggaaaaa cgccttgata tttataattc agcgaatgct caatcgttgc
    44041 ccagaaattc atcgcaagag tccgaatctg gatttccgcc aaaattttct tctcaccgct
    44101 gatcagctgt acaggatact cgatcaccag atgataagaa cggtagccac ttgctttttt
    44161 atttgtgatg taatctcgtt cttggagaac tttcatgtct tttcttttac ggatgatctc
    44221 aacaacttga tggatatctt ctacaaactg acacatgatc cttaacccgg caatatcaga
    44281 catttcttct tctaaacgtc ccattggaat atgccgtaat tgtgattttg ttacaatact
    44341 atcgactggc ttgactctcc cagtgacaaa ttcaatcggg acatgtcgat tttgttcacg
    44401 gaactgtttg cggatccccc gcagtttcac tttcaattct gatacagttt gttcatatgg
    44461 tgctaaaaat gcttcccaat ctcgttccat agctgatacc tctacttcat taacattcat
    44521 tgtttattct accatatatg caaagttttt tcgtactctt gatttatgca ttgaccaaaa
    44581 aaagaaaatt aggcaaaata gacaaaaagg agtcgatcaa atgacacaaa tgcttgaaat
    44641 cgaatataaa tctatgctga caaagcaaga gtacgagata ttcatcgctc actatcaatt
    44701 aacagataaa gatttccgtg tacagactaa tatttatttc gataccgttg atgaacagct
    44761 gaagaaacaa aattgtggcc tacggatccg tttcgttggt catcaagctg aatatacatt
    44821 aaaaacacct gctgaaaaag ggcgtctcga aacaacggat acctttataa cagaagaagc
    44881 agaagcattt atcttcgaaa aacgtctgcc tcgttcaggc gcagtttttc aaaaactttc
    44941 tgatttgaat atcgatcctg cttcattaat ccaaaccgga aagcttacaa caaaacgggc
    45001 tgaattccct attgaagaag gacttttagc tattgatgaa agctggggag acaatctaca
    45061 cgattttgaa ctggaactag aggtagggga tgcatctgtg ggaaaaattg cttttataaa
    45121 ttttttaaaa cgtttttctt taccttatcg tcctgctaag aacaagatcc aacgtatgct
    45181 tgaagctaaa aattagaaac ctttcatttt cacaaggcac ttgagttcat ttttttactt
    45241 ttttctgtta agttatagga tgtgaaagaa tctagtcact agttgtatag aatctatttt
    45301 gggggagatt catatgatcg aaatctattt atttgttaat cctttagggg aatactgttt
    45361 cgaaatggaa caacagttat tacaatttat cgaagaagag tacgggacac catcaaaaga
    45421 aaagatgcaa tttcgctttc ttcctttggt caatttgcag acaattgggg atgtcatgca
    45481 acaaaaagga atttctcaga acaatcttga ggaacgtaat cacttattct caatgactta
    45541 ttctgcagca ttggactgca aagcggcgca gtttcaagga aagaaaaaag gccgccgttt
    45601 tttgatcaaa ttgcaagaag cagtcggctg taatgacata ccatattctc aagaacttgc
    45661 tgaatccata tttgaagaaa tcggcggcga tttgaatatg tttaaagaag atcgtcagtc
    45721 tgacttcgtt aaagaagtat tcttttctga tcaaaaaatt gctcgggaaa tgggcatcac
    45781 aaaacaccct tctgcagtcg tttacaatta tgcctgcgac cgtgattttg gtgttttagt
    45841 agaagtaaaa ggtacaagta gcctttggag aatcacagag ctgtgtaaaa caacagataa
    45901 ctcatatcaa gtttttaatg gtgaacattt acatacaaat gattctcagt tccattcaag
    45961 aactagccat ttacacttgc tttctaatta aaaaaatacg tcgactccct tacaagagag
    46021 ccgacgtatt tttttcgttt ctattcgaga aaatcaaaaa tagaaagcct tataaacgat
    46081 cgatcaattc ttctaattca tttagacgtt gttcaaacat cgacattgca tcttcaatat
    46141 atgcagcctg tgtcatatca actcctgctt ttttcattac ttccacagga taatcgctgt
    46201 tacctgcttt taggtaagcc aagtagttct ctagtgcctc tggttcctgg tttagtattt
    46261 tcttcgccag tgctgaagca gcagaaaagc cagtcgagta ttggaaaaca tagtaattat
    46321 aataaaaatg cggtatccgt gaccattcga atttaatttc tgggtcttct tcgactgctg
    46381 gaccataata ttttgcattc aatttaccat aactatcact taggtattca ctagtcaatg
    46441 gcacaccttt ttcatcttcc gtatgcatga aatgctcgaa ttcagcgaat tgtgtctggc
    46501 ggaaaactgt tcctttaaac ccatccaagt aatggttgag tacataagcc cgtacacgag
    46561 ggtctttttc tgtttccaat aaatactccg ttaggatatt ttcattcgtt gtcgaagcaa
    46621 tttctgctaa aaagatggag tagtcgccgt acacataagg ctggttcgaa cgagtgaaat
    46681 aactatgaac actatgtccc atttcgtgga caagcgtaaa tagctgatcc agcgtatcat
    46741 gccaattcaa taaaatatat ggatttgtgt catagcttcc cgaagaataa gcatcgcttc
    46801 gtttcccttt attttcgaca acatcgatcc aacgttcaga gaatgctttt tctacgatgg
    46861 ccatgtattc ttcacccatt ggtttcagtg cttctaaagc tttttctttt gcttcttcgt
    46921 acgtaaaggt aattggagct tcccctaaga ccggtgtata aagatcatac atgtgcagtt
    46981 tttccacttc taataaacgt ttccgtaatt ccatgtatcg atgtaacaaa ggcaaatgct
    47041 tgtttaccac gtctaccaaa gtatcgtata cactttcagg aatatgatta ttgctcaaag
    47101 acgcttctct ggcagagctg taattacgga ctttcgcttt aaaattatgt ccttttatat
    47161 gtgtgcctaa agtagaagca aatgtatttc taaattgttc gtaaacactg tacaatccct
    47221 taaatgctgc ttcgcgcacc cttcgatccg tgctttctag caactgacca tacacgccat
    47281 gagataattg gactatttca ccattttctc cttcaatcgt tggaaaaact agatctgcat
    47341 tattcaaaac agcaaatgta tcacttgaag catcaaagat ttcacctgct ccagcaagaa
    47401 gagattcctg ctcagcagat aagacatggg ctcgattatc tactatttgc tggatataat
    47461 ggcgatagac ttccaatttt ggttcttctt tgaaatattg ccaaatctgg tcatctgaca
    47521 attgcaatat ttctggttca aaccaggaaa cggcttcact aactttcgaa aacagactgc
    47581 ttgctcttgc ataaagcgct tggtaatctg tatttccagt gtcttgatcg tttttaaggt
    47641 gcgcatatac ataaatgact tcagtttggc gataaaccct caatacgaat tcaatcgcat
    47701 ttaaaaattg agaagcgcct tgatcaagtg ttcctttgtg tttttcagat tgttttaact
    47761 cttctgataa ttccaaatat ttctcatcaa actcttggtc gcttgaaaag atcttggtca
    47821 agtcccaagt taaattttca ggcaattctt ctcgttttgg caactgcttt acttccatga
    47881 aatccactcc ttttcttccc ttagctctat ctatcaaaat agatcatagt ctaacatcca
    47941 catgtcacag catctaactt ttctactcat tcatgtgtct gcttccatca attttagcat
    48001 aactaaatct tgttttacat agaaaaccga ttcctagcct atttttatac ttactatttt
    48061 ttcaaagaag acaagtgtat gcattcgtta aaaaactgct gatagaccat ctcttcatca
    48121 atcataggaa aaagccattc ccttttatgt tcttttattt ggcaaagcca tgagttgaaa
    48181 tcaggaactt tctggttttc caaggcttct tcgtacaaca ttcgataaag aaaaacctgt
    48241 tcttgtaaat aaaagaaaaa ccgacttttt tgatagatcc acgatgatag atgcaaaaga
    48301 tgtttatgac gcaagtagca ttgttcttgt atggatactg tattcttttg cttgtgaata
    48361 agttggcgtg tcagccattt cttcccatct tcactcactt tttctatttt tttcatttgg
    48421 ttcattttaa tttcgttact agtgaatatt tctttaaggt ccctactaga aaaagtccag
    48481 cagctactgc aaaaggaaat atgccctgat acagtctctg taatatgatg atacaaataa
    48541 agcttttgtt tcttgagatc agctttccag caatgcactc ctctttttct attatagtag
    48601 cagcaacttt tttctatcaa tgagaattgc gattgtccaa gaaaagaatt accaagtatc
    48661 caccatactt ggtaactgtt attcaaataa ttttgggttc tttcaataaa tctctggtga
    48721 gacagtctag aacattggat ttctattgct agattcgcca acaaaatatc cggcctttgc
    48781 cgcaacctcg gcaaataggc ttccaaaaat actggttcta ctgactgtcc cagccaatcc
    48841 atgaagcatt cctttaactg taagtgctct tttgattctc tttcactaaa gaccgaacag
    48901 ttatctgatt tttgatgggc aaaatgagca cattttttct ttcccttttt caaaatcact
    48961 ctttttcgac agccacgaca ataatatttc tttccttttt ctgcatgttt agcaaaacag
    49021 cacttattat attcattcat tgcaagcagc atttttctcc ctctgaactt atttacgtct
    49081 aagaatttat ttacacgaaa aaagagggcg tgaaaaagct attctgcatc aagtaataag
    49141 aacagctaaa caaaaatagt tcccaatatt tttcgtttgg ttgggcttgt taccgcagat
    49201 gcaagctttt gaacacattt atacgaaaaa aagactgcga cacaattttt gtcacagtct
    49261 cttactataa tgctgattta tacaaaataa aatttcgttc gctcgatagc attacgcgcc
    49321 atcagacatt gtccatattc attcaatgtt tctggtgtac gatcgctctt ttcagcaaac
    49381 tccaaaattc gagcaatctg attctctaca tccgcttggt tgagattttc catccagaag
    49441 tgaacgacta ggtaatagcg ctcttcgaat aaatacaaat cagtccaagc agactctagt
    49501 tcgacatctg ttgcaagttg gatcacttgt tcaaaatctt caaaagcaaa agttgcttgt
    49561 ctttcctgtt cttctagggc gcttccagat aattcttcct ccggatcgct gccaataatc
    49621 tgctgacgaa gaaagtcact cacatcttct gaatcaacag tagaatcttc tgattgagaa
    49681 atttcttcat ccggaagatt tttactgata aacagttcta atccgtctcc ttttggcaaa
    49741 acttggaaag tgacagcttc gcttcctcgg aactcctctt cgatatcaac ttcttccaaa
    49801 atactataaa agaaattttc gatttctttg tgattgccaa gtaaatccaa aaatgaaacg
    49861 ccccgttcct ctaaatcttc atgaccaatt agtacacgga tcgtattttc attaatatgt
    49921 tccatttcca ttttgctaca cctcactttg ccacaatgtt taatatagat tcattgtagc
    49981 gaaatcagct taaatgtaaa gaaaaaaaat ctcgctgtta agcgaattta ataaaaccag
    50041 cggatttttc aacctttcaa gctatcttat ttaactataa catttttggc agacgaatac
    50101 tatatagccg acttttcagc taattttccc tctctatttt tcgtgcaatc atcatcttct
    50161 actacctttt tatacatcta atcaagaata ctttttgtaa aaacaaaaaa acttggaaaa
    50221 actatct
//
LOCUS       DAFKHN010000015        48927 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFKHN010000015 DAFKHN010000000
VERSION     DAFKHN010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.015"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            274..1149
                     /locus_tag="LY912_000826"
     CDS             274..1149
                     /locus_tag="LY912_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954539.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(1294..1446)
                     /locus_tag="LY912_000827"
                     /pseudo
     CDS             complement(1294..1446)
                     /locus_tag="LY912_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(1714..3045)
                     /locus_tag="LY912_000828"
     CDS             complement(1714..3045)
                     /locus_tag="LY912_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6954540.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(3194..3907)
                     /locus_tag="LY912_000829"
     CDS             complement(3194..3907)
                     /locus_tag="LY912_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6954541.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            4082..5506
                     /locus_tag="LY912_000830"
     CDS             4082..5506
                     /locus_tag="LY912_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBM6954542.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            5805..6512
                     /locus_tag="LY912_000831"
     CDS             5805..6512
                     /locus_tag="LY912_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBM6954543.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            6499..6822
                     /locus_tag="LY912_000832"
     CDS             6499..6822
                     /locus_tag="LY912_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBM6954544.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(6911..7948)
                     /locus_tag="LY912_000833"
     CDS             complement(6911..7948)
                     /locus_tag="LY912_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBM6954545.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(8269..9252)
                     /locus_tag="LY912_000834"
     CDS             complement(8269..9252)
                     /locus_tag="LY912_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBM6954546.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(9667..10437)
                     /locus_tag="LY912_000835"
     CDS             complement(9667..10437)
                     /locus_tag="LY912_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954547.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(10430..11365)
                     /locus_tag="LY912_000836"
     CDS             complement(10430..11365)
                     /locus_tag="LY912_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954548.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(11681..13330)
                     /locus_tag="LY912_000837"
     CDS             complement(11681..13330)
                     /locus_tag="LY912_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBM6954549.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(13447..16050)
                     /locus_tag="LY912_000838"
     CDS             complement(13447..16050)
                     /locus_tag="LY912_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBM6954550.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(16062..17111)
                     /locus_tag="LY912_000839"
     CDS             complement(16062..17111)
                     /locus_tag="LY912_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBM6954551.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(17137..17451)
                     /locus_tag="LY912_000840"
     CDS             complement(17137..17451)
                     /locus_tag="LY912_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBM6954552.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(17467..17913)
                     /locus_tag="LY912_000841"
     CDS             complement(17467..17913)
                     /locus_tag="LY912_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6954553.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(17914..19836)
                     /locus_tag="LY912_000842"
     CDS             complement(17914..19836)
                     /locus_tag="LY912_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBM6954554.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(20048..20944)
                     /locus_tag="LY912_000843"
     CDS             complement(20048..20944)
                     /locus_tag="LY912_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBM6954555.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(20937..21617)
                     /locus_tag="LY912_000844"
     CDS             complement(20937..21617)
                     /locus_tag="LY912_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6954556.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(21618..22400)
                     /locus_tag="LY912_000845"
     CDS             complement(21618..22400)
                     /locus_tag="LY912_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954557.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(22393..23310)
                     /locus_tag="LY912_000846"
     CDS             complement(22393..23310)
                     /locus_tag="LY912_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6954558.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(23474..23797)
                     /locus_tag="LY912_000847"
     CDS             complement(23474..23797)
                     /locus_tag="LY912_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954559.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            24585..27812
                     /gene="fss3"
                     /locus_tag="LY912_000848"
     CDS             24585..27812
                     /gene="fss3"
                     /locus_tag="LY912_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBM6954560.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            27925..28239
                     /locus_tag="LY912_000849"
     CDS             27925..28239
                     /locus_tag="LY912_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBM6954561.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            28252..28626
                     /locus_tag="LY912_000850"
     CDS             28252..28626
                     /locus_tag="LY912_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBM6954562.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            28636..28971
                     /locus_tag="LY912_000851"
     CDS             28636..28971
                     /locus_tag="LY912_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBM6954563.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            29054..30394
                     /locus_tag="LY912_000852"
     CDS             29054..30394
                     /locus_tag="LY912_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBM6954564.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            30472..31146
                     /locus_tag="LY912_000853"
     CDS             30472..31146
                     /locus_tag="LY912_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBM6954565.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            31139..31303
                     /locus_tag="LY912_000854"
     CDS             31139..31303
                     /locus_tag="LY912_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954566.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            31379..32521
                     /gene="dcm"
                     /locus_tag="LY912_000855"
                     /pseudo
     CDS             31379..32521
                     /gene="dcm"
                     /locus_tag="LY912_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            32511..32801
                     /locus_tag="LY912_000856"
     CDS             32511..32801
                     /locus_tag="LY912_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954567.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            33060..34244
                     /locus_tag="LY912_000857"
     CDS             33060..34244
                     /locus_tag="LY912_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBM6954568.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            34241..34378
                     /locus_tag="LY912_000858"
     CDS             34241..34378
                     /locus_tag="LY912_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBM6954569.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            35124..37034
                     /gene="ltrA"
                     /locus_tag="LY912_000859"
     CDS             35124..37034
                     /gene="ltrA"
                     /locus_tag="LY912_000859"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBM6954570.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            37138..37362
                     /locus_tag="LY912_000860"
     CDS             37138..37362
                     /locus_tag="LY912_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954571.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            37479..37976
                     /locus_tag="LY912_000861"
     CDS             37479..37976
                     /locus_tag="LY912_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBM6954572.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            38063..38455
                     /locus_tag="LY912_000862"
     CDS             38063..38455
                     /locus_tag="LY912_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBM6954573.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            38439..40886
                     /locus_tag="LY912_000863"
     CDS             38439..40886
                     /locus_tag="LY912_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBM6954574.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            40889..43072
                     /locus_tag="LY912_000864"
     CDS             40889..43072
                     /locus_tag="LY912_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBM6954575.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            43069..44070
                     /locus_tag="LY912_000865"
     CDS             43069..44070
                     /locus_tag="LY912_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBM6954576.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            44085..44999
                     /locus_tag="LY912_000866"
     CDS             44085..44999
                     /locus_tag="LY912_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBM6954577.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            45244..45360
                     /locus_tag="LY912_000867"
     CDS             45244..45360
                     /locus_tag="LY912_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBM6954578.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            45376..47295
                     /gene="tet(M)"
                     /locus_tag="LY912_000868"
     CDS             45376..47295
                     /gene="tet(M)"
                     /locus_tag="LY912_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBM6954579.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            47393..48766
                     /gene="tet(L)"
                     /locus_tag="LY912_000869"
     CDS             47393..48766
                     /gene="tet(L)"
                     /locus_tag="LY912_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HBM6954580.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT        15478 a         9162 c         9293 g        14994 t
ORIGIN      
        1 gcgatacatc atacctcttt tatcaattgg aacaattatt tatttctaac aaaatcactt
       61 catttttgtc agataaataa aaaacaaaaa aagttccatc tttaaaacac gctattcttt
      121 tactttttct cacattctct aagaaaagaa aaggagaatg aatttttgac aattcgagca
      181 aaagtgatta tcaaatatgt aaaatcagct acttttttct taaacgtttc tttatactaa
      241 atataaataa gtgtttcatg aaaggagaac tagatgaata attggcttga gtattttcct
      301 gaaaacgttt tggaacgcgg ttacagctat catctgcacg gttttgtccg tcatttgaac
      361 tatacaagca agtacttgtc cgcaacagtt tctggcacgg aagattataa ggtagtgatc
      421 acttgggatg aaaagaccaa catgacttgt gattgtctat atgccataga aggaaaaaaa
      481 tgcaaacaca tggctgctgt cttattcgct tacgaagaac gtccaataaa aaaatccaac
      541 tactcacttt ccgaactctc gtcccttgtt tcctccgcta gttcctctct tgtacgggag
      601 cttttaacag agattcttat agaacatccg caatttatcg aacgcttcaa agttaagatg
      661 ccatttcatg caataaatta ttcagataaa ttaacaacta tcatccataa atacgatcat
      721 attatcaaga aaaacaaaaa caggaaaaca gcgaagttca tcatggagat gcgaaagttc
      781 atccaagaag cagttgaatc gctcattcag caaaatgcct atcttcccgc attcgaattg
      841 atcaatgaag tgattgctac tctcgaaaca ttctattggg agcctgagga tgaacgaacc
      901 cttcttctga tagaggactg ttattattta tggaaagaat tattagcaga agcacctcat
      961 gcagaaaaaa ggcaaatgtt ctcttggttc gtctgccaag tcgatcatac tgacgcctct
     1021 tattcaaaac gctactccat aaaaatcctg aaagaagact ttcgggaaaa agaattttct
     1081 aaccaaaaga aaaaaataga taaaaaaact aaagaaacgg taaagaaaga cgatttcaat
     1141 gaaaaatagc aagtaaacga taacaaccat cctaaatcca caagaaatac agcagacctt
     1201 gctttaaaaa cacgaatcat gcaaaggatg aagtaaagaa gacttaacgc gtacccaata
     1261 ttagtcattt gactattagg tacgcgtttt gttttataag tcatgacaaa tttccttcgt
     1321 tgctgggtag attttccggc attgttgata gattttatga tacttttcta cattttgtaa
     1381 gagaggttcc actgcatctg tatattggat aaaattctga caacaacttt caggtgtgtc
     1441 gaaccactct aatctttaaa gataaatatt aaaataacga ttaataatat taacagtctt
     1501 tatttttcac caccaaaaac ctatctttgc atatactaaa tagacgtata tacacagata
     1561 ggtttgtctt gtgaaaaata atgattatcc ttaccaaaaa atgtttgttt ttctacatgt
     1621 tcgtacttat caaaaaatat gatccttatt gaaattactg gctatttata ttccaacgac
     1681 ttcttgtgtt aatttttgtt atctcatagt aaattatgtt tcattttcac ttaatttagt
     1741 tgtcacgtgt tcgtcaattc gtaaaaacgg taaatatata aacacacttg cggctataat
     1801 taatatttgt aaaacagctg ctcgccagtc tccggctgtt gctaaaaatc ccgatataac
     1861 tggtggcgta gtccaaggaa tttgcactac tacatgatta attaatccca cagcagttgc
     1921 aaaatatgct actgtcaaag aaaaaatcgg tgcaagcaca aagggaataa tcagactgat
     1981 attaaataca ataggcaatc caaaaataat aggttcgctt atattgaata tagcgggagt
     2041 taccgataat ttagcaaagt ccttataatc ttttctacga ctgaagataa atattgcaat
     2101 caataaagca atcgtatttc ccgatccacc cattaccgca aaggtatctt taaaggccat
     2161 attgataata tgtggaattt gctctttgtt tgcataagct gccatatttt cttgcatatt
     2221 ctgaatcaaa aacggatcta acaatgaacc tgatattact gcttgatgga taccaaatcc
     2281 aaaaaataga ttagcaatag atgtaattaa caaaaatcct ggtaaaccag ttgtaatttt
     2341 acttaatggc tctgtaacta tcgtggtaat tagcttattt atatccatat taaacaattg
     2401 aatgattata aatgacaata aagcaaacga ggtaatcgta ataatgattg ggattaatac
     2461 attaaaagac tttaaaacag cgggaggaat atttccggat agctgaatct gtagtttctt
     2521 attattagaa agtttaataa ataattctgt agccgctaat ccaacaaata tacctacaaa
     2581 cattcctgaa gctcctgtat aggatatagg tatcacaccc gtcacttcaa cagctttatc
     2641 cgcattttca ggagtaaaca tcatctgcat aggtgttaat acaacaaatg tcgaaatagc
     2701 aactaatacc gctgcaatat gatttgtata atttctgctt gcacacatat gataagatac
     2761 tgctgctaca actaataatg tagttatgct taatgtacca ttggcaattg aagtaccaat
     2821 ttgttgtaac gtggtcaatg tactagtatc gacaatttcc cccatgaatc ctgttggttc
     2881 taagatcact gaattaataa gtgtcacaaa tcctgctaac atcataaatg gcataaatgt
     2941 agcaaacgca tctcgcaaag ttcttaaatg gatctgattc cccaacttag tcgcaactat
     3001 accaaatttt tcaaatacaa tgtccttcct gctacttttg cccatatttt ttctccttta
     3061 tgcttattgt aatcgattac tttttccacc caaataatac atcacttatc aaaaaaagta
     3121 aatactttta attaaatata tatatctttt ttagtataaa aaaataagct ctgaaaaaat
     3181 aattttcccg agcttatttt tcaacaaaaa cagcttcaaa aacaaagtct tgatataaat
     3241 gtctcgatac cgaatactcg aaaggtttac cagacgatag agcaacaact ttgtctatct
     3301 caatcataaa ttcacctgga tctattttta atatttttgc gtcaaattca ttcgcagtat
     3361 ctcctttgat acgtatgtgc gaagtcttta tttccagacc cagttcattt gtgatataag
     3421 catatacaga tttctttaaa tgttttggtt ccaagcctgg tatgactgct aatggcatga
     3481 atgtttgctc aatcgagtat ggttgacaat caataaaacg gcttcgtaca atattatata
     3541 catagtcttt tacactgata cttaatttat cagctacttt tttcgatgga agttcaattg
     3601 agaaagtatg gatttctgaa tctacgtgtt cttcaccaac cacgctaaac aaaccttcgt
     3661 ttggaccaag aactcgtgag ttatcaattg gtgttctgac gacttcagtc ccatacccac
     3721 ttctacttcg caaaactcct tcggaaacaa gtaagtctac gcctttcttt actgttaact
     3781 tgcttgtatg ataaataact gccaattcat ctcctgtagg aagtttctca ccaattttat
     3841 actctccatt tacaattttt ttctttatat ctaagtaaat ttccatatac ttcgcaattt
     3901 ttttcaatgg tgaccctcca atcaaaaaca tatcttcatc tatactttaa cataaataaa
     3961 ccgataaaat ccacatcaaa attatacaca caataaaaaa gatatatata tttaaacaaa
     4021 actatttact ttaagttgta agcggtgtta tcattaagtg gaaacaggag gtaaaaaaat
     4081 tatgacaact atgaaaaagc taacttttcc agatgatttt tggtggggtt ccgcttggtc
     4141 agctgagcaa gcagaaggaa aaggagaaac aggaaaagca gagactatct gggatcgctg
     4201 gtttaaagaa caaccttacc ggttttatca acgaatcgat tcctctatta caaccgatca
     4261 catccatcaa tataaagaag atatagaact aatgaaaaaa actgggcata actcctttcg
     4321 cgtttctatt tcttgggcac gaatgtttcc aaatggcggt accggaaaag taaatcccaa
     4381 agccatttct ttctatcgaa aattattttc cgaaatgaat aataacggaa tcaaagtatt
     4441 tgccaactta tatcattttg acatgcctgc tactcttcaa gataaaggag gatgggaatc
     4501 acgtgaagta gttgatgctt atgttcatta cgctgaaact tgttttaaag aatttggtga
     4561 cttagtttgt cattggttta ccttcaatga accacttggg cctattttag gtacttatct
     4621 tgaagatttt cattatccaa acctcattga ctttaaacgc ggagcgcaag cagcattctt
     4681 cactatactt gcacacgcaa aagcaataca agtatttaaa gaactagctc ttcctagtaa
     4741 aataggcgtt attctaaatt tgagtcctac ttttcctcgt agtcaaaatc ctgctgatgt
     4801 gaaagcagca gaaatcgctg atttatttta tacgcggagc tttttagatc ctatggttaa
     4861 agggaatttt tctaaaaagc ttatcctgtt attacaagaa tataatcagc ttcctgaaga
     4921 ttatacgaaa gaagatcttg tatgtatcta cgaaaatacc gctcaaattc ttggactaaa
     4981 ctattacgag ccacgtcgcg tcaaatctcg ttcttctatg gtggatacat ctagtccatt
     5041 tttaccagag tggtttttcg aaccacatat catgcctgga cgacgaatga acgaataccg
     5101 gggatgggaa atttacgaaa aaggaattta tgatttgtgc atggatatca agaaccatta
     5161 tggaaacatc gaagcattta tctcggagaa cggaatgggc gttgcggatg aagaacgttt
     5221 catggatgat acagggcaaa taattgatga ttatcggatt gagtatatca aagatcatct
     5281 tgcttactta tggaaggcaa taaatgaagg atgtaacatt aaggggtatc atctttggac
     5341 atttattgat tgctggtcat ggatcaacgc ctataaaaac cgatatgggc tggtttcact
     5401 cgaccttact actcaaaaaa gaacaattaa aaaaagtggc gaattttaca agcaattaag
     5461 tgatacaaat ggatttagat acgatgtaga cttgttagtt gaataatatt ctaaaattcc
     5521 acttgaagtg aacacattag aaaacaagaa taatgagaaa taccaataac aaatactttt
     5581 tcttcatact tcatttatac ttgtcagtat aagagactgt gacaaatgta gtgatcctca
     5641 gaagttaggt ctggaaatct aacttgagaa gattttttta aactacgtcc agtctttttt
     5701 atttgtttaa aattgaagtt gacaagtctt cattaaaaat ttagaatatt cacaagtttg
     5761 acgacaatta tgaaaattta tgtcgtgcta aaggagtttt gttattggat gaaaagttag
     5821 atataaaaac tgcgatcaaa gacacgttac ctaccgtttt tggttatatc ggtattggac
     5881 ttgcatttgg tatcgttggg aaagctgccg ggtttcatcc gctggtcgtc acgttgatgt
     5941 ccctgctgat ctatgctggt tctgcccaat ttatcacggt cagcatgctt gctagccata
     6001 gtccactgct ctccatcgtt ctctcgacct ttctagtcaa ttcccgaatg attctgatga
     6061 gtatgacgat tgctccttat ttcaagaaaa atcggctgct tcaaaatctg ctgattggca
     6121 cattgctgac agatgaaagt ttcgcactgg gaatgaataa attgaactat actggacaaa
     6181 agttaaactt tcgttggatg aatacagcta attggatttc ttatttgacg tgggtgggtt
     6241 cttctcttgt tggcgcactt ttagggaatt ttattactga tccgaaaaag tttggtttgg
     6301 atttcgccat cgtcgctatg tttatcgggt tactttatct tcaagtcatt tctgatagaa
     6361 acacctctaa acgattacag ttgatcctga ttggtctcac tttgattctg gtatatgtcg
     6421 gactgatttt tatcccaagt aacttagtga ttttagttgt aacactgatt gggtgcggat
     6481 tgggggtgtg gatcaaacat gccttctttt gagtttacat tgctgactat tttaggttgt
     6541 actttagcaa cttggctttc taggatccta ccatttgtct tactgaaaaa attcgatttg
     6601 ccgcaaccgt tgcttgagta tttaagtttt gtcccgatcg tcattatgtc tgctttatgg
     6661 ttcagcagtc tatttaccca aaatatcgga catctgccgc agatcaatct cgaaaatgct
     6721 ttggcttcag ttcctacact tttagctgct attctttcaa aaagcttatt ggtgatcgtc
     6781 ttggtaggaa ttctttccct ttcgttgatt cgcttattat aaataaaaaa acaagagctt
     6841 atggcaaatt actgtcatgc gctcttgttt ttatcaaagt caaataagaa aaaaatcggc
     6901 gtattcttgc ttatccgttg aacggaccac taacaacgac ttttcctaat atatgtcctg
     6961 tttctacgtc tttggttgct tgtttcaagt tcttcgcatt catcccatct gaatagacct
     7021 tgctcaatgt actgcggata atcccttcat ttgctaaagc agcaatgtgc gctaaagctt
     7081 ctccttgcgt ttcgatttca tagttatagt ctgttttagc gaacatatac tcccagtcga
     7141 agctgataga ttggtttttc caaacaccta tatctaacgg ctctttgatc cctacgatcg
     7201 ttcccacatg tccaaatggt cggacaaggt gtttgatttg atcaaagtag cgggtaatat
     7261 cgaataatac agcgacatac tctacttgat cgattcctaa ttcacgaaaa cttttactta
     7321 agtcgtgatg ataatcgatt ggatagtcta cacctgtttt tttcagccat tcaaaattct
     7381 tcggacttgc agtcgcgtag acttctaggc cagcccaatg cgctagttga ttcaaaatcg
     7441 aaccgacgcc cccagctccg ttgatcacta agattttttt cccgcggttg gcattttctt
     7501 ctggagtcag accaaatttt tcaaataaca attcataagc ggtcaatgag gtcaacggca
     7561 aggctgcggc ttcttcatct gaaagatttt ttggtgcaag agcgacaata cgttcgtcaa
     7621 ccagttggta ttcttgattg cttcctgctc ttgtcgttgt acctgcgtaa aaaacgcgat
     7681 cgccgacaga aaatttttgc acttcatcac ctacagcaac aactttcccg actccatcaa
     7741 accctaagat acgtaaagca tttcttatcc cgttatcttg gcgaagtttc gtatcgacag
     7801 gattaacaga tactgcgttg acttttacca gaagatcccg tgaactgggt acaggtatct
     7861 gttctttttc atcaataaag ctttttggat catcgatcga caacccttca taaaaaccga
     7921 ctaccttcat taattccttt tctgacatac gaattcctcc ttagcttcat caagttggag
     7981 catccataca gttttcattt caatatatat agtatgctat ttgttccact tttattcatc
     8041 ataattattc tcttacttaa agtaaactat ttgcactttt ttggttaaaa aagaggttgc
     8101 gacaagactt ttgtcacaac ctcttttaaa cggtgttcaa tcaactgacc ctcggtattc
     8161 gctcaaaaaa cgacaaaata tgaggagcta tttttgtttg gctgttctta ttacttgatg
     8221 caggacagct ttttcacgac ctctaattca cggtgttcaa gcaagaaatc attgttcact
     8281 gaaaagcgtt ggatgttctt tttcaaaggt gtctaagatc tctcgtactt catcagtaga
     8341 tttcgtattc atcaactgaa ctcgcaagtc atttgctcct ggaaatcctt tgatatagat
     8401 tttaaagaaa cgatgtagtc ctgtgatgga acgcgggatg atttctgaat aatgatcttg
     8461 cagatctagt tgcagacgaa gtagtccgat cagttctttt tctgtatgtt ccctcggttc
     8521 tttttcaaat gcataaggat tcttgaaaat cccccggcca atcatgatgc catctacgcc
     8581 atatttttcg gccaattctt ctcctgtctg gcgatctggg atatctccgt tgatcgtgat
     8641 cagtgtttgc ggagcgattt ggtcacgtaa agcaatgatt ttagggatga cttcccaatg
     8701 tgcatctact ttactcatct ctttacgcgt acgcaaatgg acagaaagat tggctatatc
     8761 ttgatgaagt aggtgactga tccattcttc catctcagac atttccgtat agccgatacg
     8821 cgtcttgacg ctgacaggca aaccgccagc tttagccgct tcaatcaatt gtgccgctac
     8881 ttctgggcga aggatcaagc cactgccttt tccacgttct gctacattag ggactgggca
     8941 gcccatgttg atatcgattc cttggaagcc catttctgcc atagcaatgc tcatttctct
     9001 aaaaaattct ggcttgtctc cccaaatatg ggcaaccatc ggctgttcat cttctgtaaa
     9061 ggtcaatctt cctcgtacac tgtcttttcc atctggatga cagaaactgt ctgagtttgt
     9121 aaactcagta aagaagacat ccggtgctgc tgcatgcttt acgacatggc gaaatacaac
     9181 atctgttaca tcttccattg gtgctaaaac aaaaaaaggc tttggcagct ctttccaaaa
     9241 attagtagtc atttatttgt tactctccat tctatcaagc agtgaagtcg caatctttct
     9301 caaaaacatt gtcattatac taggaaacaa aaaaagaagc aaagtgaaca gcttaaaaga
     9361 tgtttctgat tgagcaaaaa aagactgtga caaaaatctt atcacaattc cttttccgga
     9421 ataaatggtg ttcaaaagct tgcatctgcg gtaataagtc caaccaaacg aaaaatagga
     9481 ggagctattt ttgtttggct gttcttatta cttgatgcag aacagctttt tcacaacctc
     9541 tccactaaac ggtgttcaat cagctgaccc tcggtattag ctcaacaaac gacaaaatat
     9601 gaggaactat tttcccgttt gtttctctaa tactcaggtc aaaacgctga tttcacaacc
     9661 tcttttctaa cttctcaatc ctcttccttt attgatcaaa taccaagtaa cggcgtacaa
     9721 aacaacgatg aatagcacaa gtacgatcat cgatgttgct actggcacat cgattgttcc
     9781 aaggaatccg taacggaaac cgaagatcat ataaacgatc ggattgactt tcgaaacagc
     9841 ttgccaaaat ggcggcaaca tagagatggc atagaaaacg ccacctagat aagttaacgg
     9901 ctgcaagaca aatgtaggca cgatcgatac atcgtcataa gactgagcaa aaatcccgtt
     9961 gagcagtcct gctaacgaaa acaagattgc cgtcatcaat aatgtaatga tgaccatgaa
    10021 ccatgaatac acatgaagtg gtacaaagaa caaggaaatg atcgttacga gagagccgac
    10081 gagaatactg cgacccactc cgccaatcac aaagccccaa atgatcacat gcgtaggaac
    10141 aggcgctacc aagatttctt cgatgttttt ctggaatttt tgagagaaga aggacgaaga
    10201 aacgttggca tacgaactag tgatagcaga catcataatc aaaccaggca cgatgaattc
    10261 catatatgaa aaaccaccca tgtcaccgat ccgaccaccg atcatttttc cgaaaataac
    10321 aaagtacaag gatgtcgtga tcacaggcgg aaccagtgtt tggacccaga tacgcaaata
    10381 gcggttcgtt tccttgatag ctaaactttt taatgcagta aaataaagat taaacatttt
    10441 tctcctccgt atgattattt tcttctgtga ttttcaaaaa cagttcttct aaacgattcg
    10501 acttattcct catagaaaga actttgattc cttgtcttgt cagctgatcg aagattccgt
    10561 tcaccccttg atttcgttca acttcgacag cgattgtctg ttcatcttca aatgtacaag
    10621 cgtatccttc aatcacaggt ttggtctcat atggcgctaa atcaaagata aatgtttcaa
    10681 attgcagttt ggatagaagc tctttcatac tagtattctc gatcagttca cctgattgga
    10741 tgatcccgat gttgcgacaa agcatttcag cttcttctaa ataatgcgtc gtcaaaatga
    10801 tcgttgtacc attttcgttc aattctcgga gaaactccca catctcgcgt ctcaattcaa
    10861 tatcgactcc tgctgttggt tcatccaaga tcagcaaacg tggttcatgc atcaatgccc
    10921 tagcaatcat cagtcttcgc ttcattcccc cggaaagcat acgtgcacgg acatttctct
    10981 tttcccaaag attggactgc ttcaaatatt tttcgctgcg tttcatcgct tctttgcgag
    11041 agacaccgta gtagcctgct tgattcacga cgatttgctg gaccgtttca aagggattga
    11101 aattgaactc ttgcgggact aatccaatct gttgctttgc tcggactaga tccgtatcca
    11161 gatcataacc gaagacattc acttttccag atgttttatt gactaaagaa gtaatgattc
    11221 cgatcgttgt agacttccca gctccatttg gtcctaatag cgcatagaaa tctccttctt
    11281 tcacggaaag atcgattcct cgcaatgctt cgaccccact tccataaacc tttttcaaat
    11341 tatttatttc aagcgcattt gccatttatt tcctatctcc ttatagacat gattctttat
    11401 tgtatcatgg aatacagcag atgaaaaaac aacttggttc cagcgaaaaa tcaggttgct
    11461 gggctcagga aaatctccta atgaaagaca tcaatcggac gaagtcagac aaccttttca
    11521 gaaaaaacaa atcgaagata aaggattact attcatatgt gcaacaaaag gagcgtgaga
    11581 caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaagcaaaag
    11641 ccaagatttt tgatccaata aatactttcg atcacttcgc ctatcccaat acatgccact
    11701 gccgcttttc atcaaataac gcggcttccg tttttgcggt ttctactaaa gtctctgggt
    11761 aatccaaaac tttcagcaag gcaatcgcat ttcgggtcct tgaaggtcct tcttttaatt
    11821 tgaaatcaaa actgattcct tttccttctg ttacttgttc ttcaaagtgg acattctcac
    11881 aataattctt taaaatctct gtcaattcga tatcatgtgt ggcgacaaat gctaaagatg
    11941 gatactccgc aagccaccga acgactgaag cggaagaagc aatccgttcg atcgtatttg
    12001 tcccttttaa aatctcatct acgaagcagt agcagcgttc tttggaagcc acttggtcca
    12061 acaaacgttt gatcgatttg atttctgaaa caaaataact gtcgccttca aataaatcat
    12121 cttcgattgc catggaagtc aacacatgtc caggttgcag ggtaaactgt tctgcaatcg
    12181 ctgtttggat cgtctgtgct agaatacagc tgatggctat acttttgaca tacgtagatt
    12241 ttcctgatgc attggaaccc gtgactaatg tattcttctg ccagttgacc ggattcacta
    12301 ccgcttcttt taacaatgga tgatagatat ctttcgctgt cacaccgccc tcagtaaact
    12361 ctggtcggca agtgatgggc atataagtac ggtaattcaa tattgcagcg gctacttcta
    12421 attctcccag caattcccac agcttgatgg cttcagttga atgcttttct aatttagtga
    12481 gaacgaaatg ataggagata aatggcagca tgaacatgat gttgacatat tcaaaaatca
    12541 actctgcttc actcccactc ttcatacgaa atgaaaaacc taatttaggg atgtctctta
    12601 atggtttagt ttgctgtttc agctcttctt gaagtggtgt cggcagtttt gctagctgat
    12661 tggcggctga aatcgttgaa accaaataac tcatgctatt cagctctgtt tctagtgttt
    12721 gtttcttcac tagataatag accgtattga atactaaccc accgattgcc aaatagattc
    12781 ctagtacttg tcctaaaaga agcaaaccca aacccaccag cggaagcaag ccaagaaaaa
    12841 taaataaacc tacgcgtcca atctttttac tttttccatc cgctagatat tgttttgcaa
    12901 aattatgatc tttttttcct aaacgagcga attgatattg gattttttct ctcagttgag
    12961 gattttcctg ataaaaagca atcagttttt ctaactgctg atcttcacca aaatcaaagc
    13021 tgcgtaaacg ttgatacaac gcttctgaac ctacactaga ataggtactg ttgattcctt
    13081 cgaatacttc gaacatatcc aggtcatacc aagtaagatc atcgatttcg ctatcccatg
    13141 aacggaactt cttctccgtg agccatgctt ccttcaagct ttcttcttta tcaaatctcg
    13201 gttgataagg aattttttcc catttgctac gaactgtttc ctttaatttc aaacgtgaaa
    13261 aaatgtctaa agcaactaat aaaataacag ctgcaataat aattaaaacg ataaattctc
    13321 tttgacccat atccctctcc gttcctttat ttgttagctt tagtatagca ctgttgcgct
    13381 atttgaaaag agggtaaaaa aacacctttc aaaataaaag gtgttttttt cttgtatatt
    13441 acatatttat ctctcattta tcaaaattga caaataatca tagggaggaa ttgttgttaa
    13501 ttcttgttta ttctccagtg cattgacaac tgtcccaagg gaaaggatag cctcaggtac
    13561 tattttttct tgttctgttg gattagctaa gcgaagaaca aatccttgtt catgaaaata
    13621 agaaggataa atcgatgata caattaagtc ttcaggtaat tcaatcaatg aaaatttacg
    13681 aggaacatca agttcatttt gtaatggcca aatcttgtta tctaacctgt gaataaatac
    13741 attcagtttc tgcttttgat aagaaataga ttgttctaac cgtttttctg cctgttttgc
    13801 cactttgaac tcattaaatc ttccttcttc tacattaaat ccaaaagtga ctttatactc
    13861 acctatctct tgagctagcg gtgtttccat catgacatgc ccttcatttg tcgtatctcc
    13921 tgaagctcgc ccaggtcgcc aagcaagatt aggttttcca agttcccctg ttgttgaaaa
    13981 taaggttatg attaattgat tttctatacg ttcatactct tttaaaccat ctgcataaaa
    14041 cgtaaaataa tgatcatttt ctgccacaga gacactctta tcgaatattt ctaaattaac
    14101 aggtttctct accatagttt ctgaccaatt cggaggaatg acatcagggg tattttcaat
    14161 aaatccgttt tgaatttgtg caattgattt ttcagattta tctaaaacat taattgctaa
    14221 gcgcatacga tgcgagtaaa cagtattatg aattttgagt gtgccttcaa cgatttgact
    14281 ttctcccaga ctgaacgata tttcataaga tatttcttcc atttcgggtt tttcagataa
    14341 acgatctttt aaatctttag gaagttgagc ttttccgtaa acaactaatg tttcttgtaa
    14401 agaatcttta tatactttag ctgtttctaa ttttagagat agttctgtat ctccttctaa
    14461 tggtgaataa tcatacgtat cgccatcatt tgctgaatcg atcaaatgaa cgaaatcaag
    14521 atattgtcta tctccaacta tcaaattcaa ttgcccatct ttaaaagaaa gtttatattt
    14581 attgttactt atctcagttt tgtctatctc gattgctgtt tctaattttt cattattttt
    14641 ctcaaattca acaacagtgt atcctagtgc tggcacattt acatttattt ttatgtcaag
    14701 ttcataataa gctggttcat caaaatattc gaaacctgta gcaatcatcc gataagcatt
    14761 tttccgttct ggaaaataaa cttctttttc aatgatatta tagggactac ctttgaagtg
    14821 tattttcttt gaatcagcta ctacatgcac gattttcgat ccactataat tctcagtcgt
    14881 tgtgttgaaa acaaggactt cattcgattt tagctttaat gcatcagcca tccgttttac
    14941 aataaggttt tcgattccgt cagctatctc attagcttct ttgattcgat ggaaaatatc
    15001 ttccgcaaca ttatctgaaa cacagccacc aatactatca tgagcctggt tttgcaaaat
    15061 ctttttccat aaccgacgaa gtaggccttt actgatatgg ataccatttc tttctgcaat
    15121 cagcatgagc ggctcaactc gttttagaat tttttgttcc aatttaaaat tttctatttt
    15181 catttttgtt cttactgagc caatagaacg atgaacacga gagtaaaccg gctgacgaag
    15241 ttcaccttta tattcaggta attctttttt gtttctgata acttctacat aagaaggata
    15301 atctgaaata atattgtgga atttactgta tttattcaac ttctctacga cttgatcaaa
    15361 atttaaaatc attgactttt gatctacacc cgaaggtact aaaatatctt tgttttttcc
    15421 ttgcatatga agcatttcaa ctgcttcatc caacttttct tttgcaaatt caggaatatc
    15481 tttaattgcg tctaaggtca tcattccagt catataacca aatggaaaat tcatggcata
    15541 aacaaattta tctcccaatc ctttccagat aaaataagga gatggaacca tcgtttcaaa
    15601 gtttaatcct cgccaacaca tgaaattatc gatttctact tgatgcaaaa gtgtaggcaa
    15661 attcgcattg aacccaaacg tgtcaggcaa ataccctacc atcattggat ctccatattt
    15721 aaggatcgta tcactgattc caatcattaa gtttcttaaa attgattcag catccactaa
    15781 taaggcatct gtttgtgcat accacggtcc cacgaatagt tgtcctgttt tcatcagtcg
    15841 ttggataacc ttaagctttt gcggattgat ctccaaatac tcatcgacga ttgaagtttg
    15901 tccatctaaa caaaagttta ctttagggtt cctttccaat tcatctagaa cttcagtaaa
    15961 gacctgatca gacaatacga tggcatcttc atttgtaaaa taccattctc tgtcccagtg
    16021 cgtgtgttga attatatgtg catttaccat atcagattct cctactttcc ttcttctact
    16081 gaatttactt gttgttcttt tttatacttg atggatttta gtgcattgac cattaacgct
    16141 gtaaccactc ccccaataac aattgatact aaatataaag gtatattcgt aacaaaagga
    16201 attgccataa aggttgaaag cattgtttct tgagtaacac caaaaaatcc atttagacca
    16261 catgctactg cagtgcccac cacgatgctt ggtattactc gtaaaggatc tttcacggca
    16321 aacgggatcg tcccttcagt aatccccaca aggcccataa tcatagctgt ctttgcatta
    16381 tctcgttccg attcatcata aagttttttg tttaaaattg ttgctaaaaa cattccaaat
    16441 ggcggaatag caattcctaa taacatggct gtactaggtc caaagcttcc gcttgaaaaa
    16501 gaagcaaccc caaaagcata tgcgatttta ttgataggtc ctcccatatc aaacgccatc
    16561 attcctccta aaatagccga catcaaagca gcatttgctc ctgacatgcc ttctagccaa
    16621 ttagtcagtc ctgttgtcat tgcttgaata ggcgtagcta gtacatacca taatatgatt
    16681 ccaacaacta atgtagtaac aaaaggaatc agcataattg attttagact aataacttgc
    16741 atcggtactt ttactttttt caatgcatta gctaaatagc cacaagctaa tccagcaacc
    16801 attcctccaa taaatcccat accaagattt tgacacatca tcccagtgat aaaagctggt
    16861 gctagaccgg gacggtcagc aattgaatat gcgatatagg ctgaaatcat cggtacgata
    16921 aactgtaatc ccgtctgacc aatcattcgc aggactcccc agaatgtatc cgtctggtcc
    16981 caaacacctg tgccaccaaa aatgactgca atagaagtta gtaaccctgc tgctacgaca
    17041 agcgggatca tataggaaac cccactttgg aaatgattta gaatttctct tccttgtttc
    17101 ttgaattcca ttagtaactc ccccacgata tattttttat ttgttaatta atgcaattgc
    17161 ttcatcaatc gtctcttcac catcttttac tacctctgag gtccctactg ttaaaatcgg
    17221 tttaccgtca aagcgacctc gttctgaaac atttgtatct actgcaaata tgacaacatc
    17281 tgcctcggaa acatccgaaa ttgaaagttt gttttctatc cccatagccc cctgtgtttc
    17341 tactttaata tctaaccctt tcttcttcgc aaacttttct aaattagctt ttgccatata
    17401 agtatgggca atccctgcga tacatgctgt tactgctact atttttgtca tatgaaattc
    17461 ctccttttaa aatgatagag cttttaccaa ttctttttta tttctcgaat cttttattct
    17521 tttaacaaac tcgtcatcca tcaatcttcc agataattct gctaaaatac gtaaatgatt
    17581 agtaccttta tcagtgtctt ttattgctaa caaaaagacg agatcaactg gttgatcatc
    17641 taatgcgccc cattcaacag accgctttaa cttggctaca gccactgttg attcaattac
    17701 tgctaggctt ttgccatgag gaatggcgat atttttccca attcctgtgg tcatatggtt
    17761 ttctctgtca aatacgtctt tttgaaattg tttgtggtca gacacaaacc cattagtctc
    17821 taacaatttc gataattttt cgactacact ttttttatca gatgcattta aatctatcac
    17881 tatattattt atattgattt tttcactgat catttataag ccttctttca atatataaac
    17941 taatttttca aacgacgaac tcgtttttaa atttgctaat aactcatgat tcgaagcgat
    18001 ttcattgaat gtttcataaa ttttattcaa ttcaggtttt actttttcat taagtgcaaa
    18061 aaagaaaaca gaatgaacaa gtgtcccatc ccaatcaatt ccttctggat taacgtagac
    18121 acagattact ggctttttta taaaatctac ttcgatatgc ggcatagcaa aatcattcat
    18181 cgctgttgaa gatagttttt ctcttttgat tgctccctct agtatccctt ctttcgcgta
    18241 attttctttt accaattttt tggtaattat atttaaaacg ttcacttgat tatcctttat
    18301 ttggtgggta aaaaagcaaa atcgtttatc taataaattt agaaaagcat cttctgtttg
    18361 ttcatttaac tgtagatact gttttacttt tctgacatct gcccctaaca tcaaaggact
    18421 aacaacaata acaggaaaat ttgtattttc aatcggaatc gtgcttataa caagttcatc
    18481 agtgactttt ctatcttgta gttcattgat gcttagtaca tcttctatct caaccatatc
    18541 tgcaaaaccg ttatttattc tttgctctaa taattttgat gttccatatc cgctactaca
    18601 aactaatatc actttcgttt tgtcaggttt gtaacgatcc aaaagtgatt gaatatggag
    18661 tgttacgtaa gcgatttcat cttcattaaa atgtatacag aatctctctt cgatttcctc
    18721 taataaatct acacttatca taaatgacct tttaaaagaa tatttgattt tgtccgtata
    18781 agggttatag atatttactc ccaatttgag tcttttaact gctgcattga gatgtaatac
    18841 tagattattg atcaattctt catcaggata aaattcattt aatttaattc ttactaactc
    18901 ttgtagctca acacccatat ctaaatagga aagcttcgtt tgatctaagt cgtgattcat
    18961 agcatttttt tcaatcgaag taatgtgaat gtcaacataa gcttgttcat ctattggcac
    19021 aataattgaa aatgcttttt caatcatttt gattaaaata agtgtattct ttgagatttc
    19081 ttcttcagaa ttattactac gtgataagaa attgcttgtt tcaatccttt ctatcgcaat
    19141 agcaaggtgg atagctaaag tttgaaattc ataatctgta aatttcaatt gtgtcttatt
    19201 catgtatcga ttaagcaatt cggctacttt tttcaatatg tccttattta agaaattatt
    19261 cgcttcacca atgaaattga tattcaagtc taagagatct gttttactgt tagatgctgt
    19321 aaagccaccc caataatagt tcacaacttc tgacatcaac cttcttttac ttttttcatc
    19381 agctttgatg cgcacgccat ttcgatctga aactaaggac atcccatgct tgtttagtct
    19441 ttttctaaca tctttcattg tgctttctac cgtcgacctg ctcacgtata attcgtcagc
    19501 aagattttga atctttagag aatcattagt attcaataat ttagcaaaca cataagttag
    19561 acggtcctcc ggagagtctg cgatattgat tttatgactg gataataaat ttcgaagtgt
    19621 ttcttttttt ccaataagcg aaacgccttt tttaggttga accaacattt gtacatctgg
    19681 cattttttgg attatttctt tcaaaattaa aatatctttg ctaattgttt tcgtagatac
    19741 atataattgt tctgataatt ctttgtaagt tgtgtgctca ttttcaatca aaaagtatag
    19801 tattttcatt tgccgttcgc taaattcgat gcccattatc ttcacctcct gaatacagct
    19861 taagtgtaca attattatct ctattttcat acagaagaaa gttcttgatt aatgtagaag
    19921 tttctaatat tcttgattat ttcaaatcaa taaaaaagcc tgcaatattt atatcacagg
    19981 cttttttctc tattaaatat atataagata atacattttt ctactagttc tcactaatct
    20041 tgtataatta aaccctccgc aacttgacgg agatggagaa gatgcccccg tctaatctag
    20101 cggtcatctc tcctcccatt ccttccacca atttttttga caggtaaagc ccgattccgc
    20161 tagattccgt atttgtgcgg ctggtatttt cggtataaaa acgctggaag actttttcaa
    20221 cagaggtttg cgttcctggt ttgataggat tggccactgt taatcgaatg aatggatcct
    20281 cttttgaaaa tgtcaccttt gcttgtccat ctgcataacg caataaattc tgtatgatat
    20341 tttgcagcac tcgcagcaac atgagcggat ctgctaatac agttgtattt atcgagtgtt
    20401 cagcgaacgc tacctcgata tttttctcag aaaattgttc ataaaaagag aaaaatactt
    20461 cttccacctc tttagaaaaa gaaagcgtat ggagatccat ttctttttgc ttcgtctcta
    20521 ttcgagcaag atcataaaac tgatccgtca tactgagtaa tcttgcaaca gattgtttga
    20581 tgatcgttaa atacttctcc cgtttctccg tatcctctac ctgttccagt aattgtacat
    20641 aaccgttaat agcagtcaaa ggagttctga gatcatgaga aaggccgacg atcgatagtc
    20701 tgatgttttc ttccatttct tgaaatgctt gtcctttttg ttcattttca tccaaccatg
    20761 tattcagtgc atctactagg tccattagat tcttttctcg aaattcgact gaaagacgac
    20821 caccatattc ttgtcgttca gaaagagtgg cgattttctt agttaatctc ttgatttccc
    20881 tttgcaggaa gaaaataaaa cttcccataa agataacaac gagaagcaac agccatttaa
    20941 tcaaatctaa accccactcc ccacaccgta tgaatataca cagcatgtgc ctttgctagc
    21001 ttccctcgaa gattggaaat atgcatattc actgttttct cactatcaaa atatggttct
    21061 tgccaaactg tttcataaag atttgctcgc gaaaatactt ttttcggatg ttctaaaaaa
    21121 agcttcagca gatcgaattc tcttcctgtc aaatggacag ccacaccatt cacatttaca
    21181 tccctcgact ctttgtccag taagatttcc ttgtaataga tgcgttgcga cagatctttt
    21241 acttggacag aagtctgatg acgaagttgg atgccgattc gtaacaaaag ttcttcgata
    21301 tcaaatggtt tcgtcacata gtcatccgct cctgctgcca acaaggaaac tttatctctt
    21361 tgatcgcttt ttgctgaaag aacgatgatc ggaacattcg atgtctgtcg gatttctgct
    21421 aacaatgctt cacctgaaag ccctggaagc atgagatcta gaaggatcaa atcgacagga
    21481 tatgtgctta acaataattt tccttccgta cctgaataag catcaagaag tttgtatctc
    21541 tgttcaagaa cctcctccag taaggaatga acagcttcat cgtcttcgat aatcaaaata
    21601 gtttccagca ggaccaccta cttaatgtca gatttttgga aaataaacat tcctagagct
    21661 gatgatacca cgattgttac tagactgacc agaatcattt tcggtgcttg cgaataagtt
    21721 gcttgttgcg caaagtccgt atacatgagc cacgtttccg taaaccactc cgttagaaat
    21781 tccaagcctt tgatttttgc gaaaacaccg ggaatgaagg ccgttcccat gatataaaga
    21841 aaagaaagaa gcaaactgac actggtactt ctagtgatga atgtcaaagc cactggaaca
    21901 gataatgtcc ctaatgtcag cagaagcaat acaggaaata cttttagaac ataatttcca
    21961 tagtttttga ttccctcaac ttcaccaaat ccgaaagcaa gtgtgtaagc aagcatggct
    22021 agtcccgtga tcaaaaccac gccaagtgtt gtgatcaaaa gcgtaacgag aagtttcgac
    22081 acataataag tcattcgatt ccgtcctaaa gataacgtat tgcgaatcgt accgttttga
    22141 aattcttccc caatataaaa gcacgcaaat gctgcgaaag ccagaagaat ccatgcagcc
    22201 attttttcta ccattaaaat ccctgttgca ccgttgatga ctgtatccgt tgcttggttt
    22261 aattcattgc cgtattttgt atgcatatac cattcgttcc aagaataaaa aagcggaagt
    22321 acgaccatca gtcctagtga gacccacatt ttacggctct tccatacttt tattttttca
    22381 gcagttaata gattaaacat gtggattgcc tccagttaat tgtaagaaat aatcttccag
    22441 tttttgccca actaggtgaa taccatccac aggaactttt gcttctacca atgcttgatt
    22501 gatggctgct acttggtcaa ttccttcaaa aagctggata acacggctag attgtacaaa
    22561 ataatcccta taaccaagag agtcgagaac cgttactgct tgttccgtcg ccgaagtgtc
    22621 aatttttata aattgacgag attcttgtgc caattcttct ttcgataatt ctttgatcaa
    22681 gtgtccttca tgcaaaatac catagtgagt ggcgatctgt gacaattcat ctagcaagtg
    22741 gctagaaagc aagacggtga tgccccgttc ttttaccaaa cgttggatga tttctcgcat
    22801 ttctgccatc cctgctggat ccatcccatt cgtcggttca tccaaaatca aaaattctgg
    22861 attcgtgatc agtgcatttg caatagctaa acgctggcgc atacctaaag agaaattctt
    22921 tgctttcttt ttccctgtat tttccaatcg catcattttc agcaggtctt cgatttctct
    22981 atccgacaca ccgccgttcg ctgcttggat acgtaggtta tctcttgcag ttaattctgg
    23041 ataaagagca ggggtttcaa tcgattgacc catacgtcgt cttgctgcct gcaaatccgt
    23101 cgttccaaat aattcgatcg aaccttcatc aatcgagatc aaacccataa tagttctcat
    23161 aaaggtagac ttacccgctc cattttcccc aatcaatcca tagatcattc cacgtttgat
    23221 ttcgattgat actttatcta atgctttggc agcaccgtat tttttggtta taccagttgc
    23281 tttcaagacc gtttcatttc caaaatccat acttatcctt ctttcttatt gatgagtgaa
    23341 gtatagttga cgggtataaa gaaagcagcc agaaatgtat aaagaaagtg taaattttcc
    23401 aattgaatgt caaaaaaaac aatcggacaa tacgtgtctt tcctattatc aggcagtttg
    23461 ttatacgctt gtatcagttt cctgattctt tcttttcgac caaagtcgtt tctctgtatt
    23521 cctcttcact gaaaattttt gcttctttca gatcaagctt gagtaatttt accagaccgg
    23581 ttataaggat aactatagca agactccctc ccagaaaaat tagactgtct cgcagacgtg
    23641 gttgcgttgt cttccaatca aagagcgcac caaacagtgc taatccaagt ggactggcca
    23701 ccatggtaat cgttgttatc gttgacataa gtcgtccttg tatatgcgtt ggaacttctc
    23761 gctgaagcca gaccatataa aaagcaaaag aaaacattaa tccttaaaaa cggacttatg
    23821 aaaaataata catgccgttt gggatttaca attagctacc aaataagagg ttatgacaaa
    23881 agacttttca caatcccttc ttccgaataa acggtgttct cctgccaact cctcggtcac
    23941 aagtcacaat atttatcaaa catgagaagc aatttttgta aattccttct tatttcttga
    24001 agctgaccac ttctgtcaca acctcagaag cggataaata atattgtttg atgatacttt
    24061 atctttttcc cgtttgttta tagatcgaat gatattatag accaagaatc ctacctatta
    24121 acatagctaa aaacacaaaa aaggcacttt ccaaattgtg gaaagtgcca gaaaagttag
    24181 gattaaggta actgcgctca gcattgcttc gcccagtacg attctcgtaa ctcgtgaact
    24241 cgaacgataa tcgcaattaa cgttttgaga actgtgaagc tttacgggct ttcttaagac
    24301 ctggtttttt cttcgtatca ttgaataagt ttgaaaaacc ttgatttata aaggttttcc
    24361 cgtaaatata ttttattata tttgattaaa tttgaaatgt ttgtgttcta aaatgtgttc
    24421 taatttaaag gcagtatatt tcgtatttta gattaaattt ttaggctcat tcattctcaa
    24481 atccattcta ttcagtcaat aaaaatttta aaaagacttt ataaacaaag atgttcaagc
    24541 gagcatctta tttttttgtg cttaatttga aaggagaaca tttcatgtat aaaaaacaaa
    24601 aaaagaaatt atgtgtatta actattttga gtttggctgt tcaagcaatt gttggagcaa
    24661 ttgctcctac gattactttt gctgatgaaa ttacccatcc acaaacggta accgtagaac
    24721 tagatttagc acatcaatat gctgttgaag gaacttttag tgatggtcgt ccaatgtcag
    24781 aagtcactgt tccgcattat gcagtgtaca acggctttaa acaagatatt ttctgtattg
    24841 aaccaggagt cccgatttac aatgagttca ctcctggcta tgagaaaaac ccgttaccag
    24901 atatgtccga taaagccaaa ttagtttccg ttttatggaa aaaagtaggt acagatgcag
    24961 atactcatat tgtggcacag aagatgatct ggcaagaagt taatgggtat acccttcact
    25021 caataaaacg atcagatggt agtgccgtaa atatcgcagc cattgaggca aaaataaatc
    25081 aagccattga cgattatcag aagaaaccaa ccttccataa tagtacggct aaaacagtat
    25141 tagggcaatc gactactgtg acggatacga ataatctgaa tttgtcagag ttcgatgagg
    25201 ttgtggaaaa tgccgcaaac attgattatc gtgtgaatgg taatcagttg ataatcaccc
    25261 caaatgccaa ttcaaaagaa agtggtgtgc tgacgcttaa gaaatctgct ggtaccggaa
    25321 cacctgtcgc ctataaaaag gctggccaac agactttaat ggccggggcg attgataaac
    25381 ctaataccta cacaatcaaa attgatgtgg aaacggaggg ttctttaaag atcaaaaaag
    25441 tcgataaaga atcgggtgat gttgtaccag gaacggtttt ccatttagac tttggaaaaa
    25501 ctttacctgc aaaagacgtg actactgaca aagaaggcat tgctacattg gatgagattc
    25561 ctcatggtac aaaagtaacc attaccgaaa aatcagtacc ggcgccttat acgattgata
    25621 ccacccccat gactaccacc attaaagcag gcgaaaccat ttacgtgact tcaaaaaacg
    25681 cacgggaaaa agggcaaatc attctggata aaagcggagt tgaaacaggg agtgatcttt
    25741 ggaatgacaa ttattcctta gctggtaata cgtttgccat tcgcaaagac agtccaaccg
    25801 gtgaaatcgt tcaagaaatg accacggatg aaaacggtca tgcggaaaca ccaaaagaga
    25861 ttgctaatgc gttggaattg ggaacctatt atgtgaccga aactaaagct agtcatgggt
    25921 tcgtgaatac gttcaaacct gtaaaagtcg aattgaagta tgccaatcaa accgtagccc
    25981 ctgttaccag taacgtaaaa gggcaaaatc aagaagtcac tggcgaaacc actttgacga
    26041 aagaagacaa agatactggg gataaagcac aaggtaaggc agtctttgag ggtgctgaat
    26101 acaccttgtt tactgctaag gatggaaaag ctgttaaatg gagtgaggct tttaaaccag
    26161 agttagcgaa gggaacgaaa ggttctgatg aaacggtcac tttgacttta gacgaaaaga
    26221 accaagttgc cgttaaacat ttagctatca acgagtatta ttgccaagaa acaaaagcgc
    26281 ccgaaggata tagccttgat gaaacaaagt atcctgtatc catcaaaaag gtggatgata
    26341 gcgaaaaaaa tgccgtgatt acccgaaatg ttacggcaaa agaacaagtg attcgctttg
    26401 gctttgattt ctttaaattt gctggatcag ctgcgggcac taccgaaact ggcttcaatg
    26461 atctgacctt taaagtgtcg ccattggaag ggaccaatga aatcacaggt gccgaagatg
    26521 aagcgaccac agcttataac gagcaattag ggtttgatgg ttatggcaag tttgaaaatc
    26581 ttccttatgg ggattattta cttgaagaag tagaagcccc agaaggtttt caaaagatta
    26641 cgccattaga aatccgttct acttttaagg aaaacaaaga agactttgtg aagagtgagt
    26701 atgtctttac cattaccgaa caagaccaaa aacaaccaat taaaacggtg accgttcctt
    26761 acgagaagct gacgaacaaa gcattttctg ttagtttgaa ccgtttaatg ctctatgatt
    26821 tgcctgagga agaagatagt ttaacttctc ttgcgacttg gaaagacgga aacaaagaat
    26881 taacttctct ggattctacc gagctagttg ataaattgag ttacaatcta catgaaatca
    26941 aagaagactg gtatgtggta gcgcaagcca ttgatgtgga tgcgacaaaa gctgcccaag
    27001 aaaaagatga aaaagccaaa ccagtggtga ttgcagaaac aagcgcaacg ttggcgaaca
    27061 aagagaaaac aggaacttgg aaaattcagc ataaattaac cgccgaacaa gttttaaata
    27121 aaactattgt cttattcaac tatgtgtatg aaaataagga agcttttgaa gcaggcgata
    27181 agccagtagc gaaggatgtt agcttgaata accaagccca aactgtcagt tgtacagtgg
    27241 aacaccatgt ttctatccaa acaaaggccc acctagaaaa cggttctcag acctttactc
    27301 atggtgatgt ggtggatatg tttgatgatg tgtcgattac tcatgatgta ctggatggct
    27361 caaaagaagc tttcgaaaca attctgtatg ctttattacc ggatggtaca aacaaagaaa
    27421 tttggaaatc tggcaagatt gattatgaag taaatgataa agaattcacc aaaactgtgc
    27481 ttgcgaaaaa agtagatacc ggaaaatatc cagaaggaac caagtttact tttgcggaaa
    27541 tcaattacga taaagatggg aatatcaatg gaaaacacaa tgaagatttg aaagaaaaat
    27601 ctcaaacctt aacaccaaaa gaagttccaa ccatactaag tacgccgaaa caaccggaaa
    27661 caccaactgt tccaagtggc tctcaagaat ctagtcccac agtgaagacc ttccctcaaa
    27721 ccggggagaa aaattccaat gttttactgt tcattggttt tactttgatt tttgcgacgg
    27781 cgggctatta tttctggaat cgccggaact aaggtgatga gatgatacaa gtaaatccta
    27841 agaaccaacg tgcgcgaccg cctcctaaaa aagtagtcgc gctatttttg tatccaaaac
    27901 taacaatgaa aagaggaaaa gaagatggaa ttgaaatttg tcgtgccaga tatggctgaa
    27961 acctttggaa agttaagtta tgccggtgaa ggagaaatta taacagaagg atatggacgg
    28021 aatactacgg tgattggtcg cagttatcat ttgtattcca gtaagcaacg ggccgatgat
    28081 attgaggtgg tagtagctgc ggaagccggt gaaaaggatt ttgatcaaga ccaaccgcta
    28141 aaagccgtga atccccattt ggttgccaaa ggctatgaga ttgagaatcg tgggtttact
    28201 gattacgtgt tgtatgttga tgatttagtg aaagcatagg aggaaaagaa gatgagatta
    28261 acagaaggta ttgtcgtaga ttcaggttta acatttggga agttgcgttt ttccgcatta
    28321 cgccgagaag tacggaagca aaatgaggat ggaacaattg gtaatgaggt aaaagaacga
    28381 acctataatt taaaatcctc tgcacaaggg cgaatgattc aagttagtat cccagctaat
    28441 gtacccttac gcgagtttgc ttatgatgca gaggtagagt tggtcaatcc aatcgtggat
    28501 accgttgcca attatgtttt tcgagaagga actaccgtta attggttcat taaggcggat
    28561 gatttagtct tgaagcggca gccgaatcaa ggaaatccta cgaaccaaaa tgaaagaaag
    28621 aaataggtga agattatgga aattaatgtt gaacatattt tagattgtct cgatcaatat
    28681 ggaaaaggcg agctgactga ggaacaactc gttaaagcat taacctctga tgaaaaaatg
    28741 tttctgatta tacatcaagg tttacttgga gaaaatagcg acagtgaaga agactctgat
    28801 gtactagact ggttaggaga agaagagtct ttctttatag ttgtcgaagt aaatgaaaac
    28861 ttatgtcggc aggcagaatc cattttggaa gaaattggtg tggagatgcc ggatgctatt
    28921 gaaggctttt taaatcaatt ggttgaaacg aaacaactcc cctcctcgta gcagtaaatg
    28981 actagcataa ctttttgaaa ttgcctaatg aaatcctatt gggctttttc gattggaggt
    29041 ggaaaccatc aaaatgtaca aaggacatcg catacgcgca ggagatcagc acttggttta
    29101 tcactttgtt cttggctggc tactcgctct gttcatcggt tggatgagcg tcttttattt
    29161 tcaagagttt agacaatttg atatttctaa gctatcactt tctactattg aaatcgtttg
    29221 gtctataaaa gatttagtat gtctgcttgg aagtctcgct ttttcaggag ctatgatatt
    29281 gctttatatt cacttttttc ttgatcattg gcgaagcttg tggcatcgac aaaagctagc
    29341 tcggatgatt ctagagaacc attggtatga agtgaaacaa actcaaagtg aaggcttttt
    29401 caaagatttg aatagtagcc gaaccagaga gactatcagt tacttcccca aaatctgtta
    29461 tcgaatgaaa gatggattac tgtctattcg cgttcaaatt tcacttggga aataccaaga
    29521 tcagctttta aaattggaaa agaagttaga aagcggactg tattgtgagt tagtagaaaa
    29581 ggaactcaaa gactcctatg tggagtatac tttactgtat gatatgatcg ccaatcgaat
    29641 tgggatagac gaagtagtgg cagaaaatgg gactctgcga ttgatgaaaa atcaagtatg
    29701 ggcttatgat tctttacccc atatgttaat cgctggtggc acgggtggag ggaagaccta
    29761 tttcctcctc accattatcg aagcactatt gaagtcagat gcagaattgt ttatcctcga
    29821 tcccaaaaat gcagatttag ctgatttagg tacggtgatg cctcatgttt attcacaaaa
    29881 ggaagaaatt tctgcttgtg tggaagattt ctatgaacgt atgatggctc gtagcaaggc
    29941 aatgaaagaa atgtctaact acaaaacagg agagaattat gcctatcttg gacttccacc
    30001 caacttttta atctttgatg aatacgtggc ttatatggag atgttaacga cgaaagaaag
    30061 tgcggtgatt ttgaataagc tcaaacaaat cgtgatgttg ggtcgtcaat ctggtttctt
    30121 tctgattttg gcttgccaaa ggccggatgc gaaatattta ggagacggaa tccgcgatca
    30181 attcaacttt cgcgtggctt tgggtcgtat gagtgaactc ggatattcca tgatgtttgg
    30241 ggaggtcgaa aaaaacttct ttatgaagca catcaaaggt cgaggttatg tggatacagg
    30301 tggcagtgtg attagtgagt tttatacgcc acttgtacca aaagggtatg atttcttaga
    30361 ttcaattagt aaattagaaa agatgaatga ttgagtgatc ttcaatactg actttatact
    30421 tcaagtaacg tataatactt ttatatagta ggaagaaagg ggataattaa tatggaaagt
    30481 aatgattctt atttagagta tgcaaaagca aataaggata agtttatttc ttatattatc
    30541 aaagggaaat cccccgaagt tggacgagac gcagttttta tggcagggag tcctggggct
    30601 ggaaaatcag aggttgccat tggattagct gagaattatg ataaccatgt gattattgat
    30661 gcggattact ttcgcaccca gtttcctgat tataatggaa aaaactctag tctctttcaa
    30721 aaagcatctt cttggttggt agagcaggca tttagatatg tcttagatca tggctattct
    30781 tttattctgg atgcaacttt tgcaatatta agtgctgaaa aaaatatctc gcgggcgttg
    30841 aaaaaacatt ttcgagtgac gattttctat gtttatcaag accctaaaat cgcttggaaa
    30901 tttacacaag aacgtgaaat tgcagaggga cgtcatgtgc cgaaaaaggc atttattaac
    30961 gcttttttca aatcaagaga gaacattgca aaagtaaaga gtaaacatcc agatgtattg
    31021 cttcatatca taataaaaga ttatacgaat aatatttccg aagttcatta tgctacggat
    31081 aatctagaat tatttttacc actagggtat agtaggaaag atttggaggt tcaattacat
    31141 gactgagaaa gaacaagtaa cgaaaattgt aaagaaatac aataagagca ttgcggattt
    31201 atcggaaaat gctactgcaa aagagttcaa aacggtgatt aaatatgtag ccgatcaggc
    31261 caatgaaaaa caacggaaat tagttggatt aaataaaaaa tagtaggaca aattaataat
    31321 gtatgagcca agagcaaaat gttcttggct tttttctttg caatgaatga ggtaatgtat
    31381 gagattttta gatttattcg ccggtattgg tggctttcgt ttaggtatgg aacaggcgag
    31441 ccatcattgt atcggttttt gtgaaattga taaatttgct agacgtagtt ataaagcaat
    31501 tcatgataca agtaaggagg tggaaatgca tgacatcaca agtgtatcag atgagtttat
    31561 tcaatccctc ggaccagtgg acatcctttg cggcggattt ccgtgccaag ctttttcaat
    31621 tgcgggaaag cggcaaagat tttccgatac tcgaggtact ttattctttg aaatcgctcg
    31681 gttcaccact cttctccgac ctaagctttt attccttgag aacgtccgag gattgctcaa
    31741 tcacgaagga ggggctacgt tcgagacgat cctccgaacg ctggatggat tggggtatga
    31801 cgtggagtgg taggtgctta actcaaaggc ctacattccc caaagccggg agcggatatt
    31861 ccttatcgga cattctcgag acgcatgtac cgaacaagta tttcctatca ttggaccgtc
    31921 ttcaacatct gatcaaaaca tcagaaattt ggtaaatatc aatccttcca atcgaggaat
    31981 gggtggacaa gtctatggtt cagatggcgt agcgccaacc ttaacaggtg atgaaggaat
    32041 caaaatcgca ctgccagcaa gggatggaat ctctgtagca ggactattac cgggaaagtt
    32101 tgaacaaggt aatcgagttt atgaagttac tggaaccgcc cccaccttgt caacgaaaca
    32161 aggtggtaca aaaatcatga ttcgaaaaaa tgaaacagaa tatcaagagg tgaagccaga
    32221 agacagtgtg aatctggctt ttcctaattc cacaagtcgc cgaggtcgtc tgggaaaaca
    32281 gagtgttcat accttactaa caggagacca acaagcgatc gtcacggatc agtatcaaat
    32341 tcggaagcta acacctagag agtgttggcg acttcagggc tttcccgatt gggcttttga
    32401 tcgagattct caagtcaatt cagatagtca gttgtataag caagccggaa actctgtaac
    32461 agttccggtc atttttgata ttgccagaag attaaaagag ttggatgtac atggtttatg
    32521 atgagttgat tggagaaatt tattgggtga ttggaaagat tcagtcagac ccagaattag
    32581 aagaacaatt gcgacggtta aaatttgata ttcgcaagaa tggtgtcaaa gtcgctggcg
    32641 atccatattt aatgaatgag gagacggatg ctcgaattga aataaatcaa gtaattgcag
    32701 aatttgagcg gattgcggac caagcaaaag aaccagatat tcgtcaatac ttgttagaaa
    32761 tgaaagcaga gttggaagta aatggtatta cagatgagta acctaaacca acacaactga
    32821 ctgttaggcg ctgaccgcgg aggattcgcg aagcagaaat cctccgtggt gctgtgcctg
    32881 ttcatggacg gcgttagccg accatgatgt ctcacccccg tatctaacag gggggtacaa
    32941 aaacacaaaa aataagtaag caaccattaa gaatgcttgt tgtatcaaag atagtaagta
    33001 atttgtatag gtgttaactc atttgaaaaa gttaacacct tgaatttgga ggtgagaact
    33061 tggcacaacg gaatttagat tatcggctat taaaagaccg acgcaacgaa tacggcgttt
    33121 cacaaaataa attggctacg gcttgtggac ttagtcggcc gtacttaaat cagatagaaa
    33181 atggtggcgt aaccgcatct ataaaaacca tgaggaaaat ttttgaccaa ctggaaagct
    33241 ttaatcccga tttgcctttg acgttactgt ttgactatgt aaggattcgc tttcccacaa
    33301 cggatgcacg aaaaattatt caagaaattc tccatttgaa atttgagtat atgctccatg
    33361 aagattatgc cttttactcc tatcaagaac agtatgtcat gggtgatatt gtggtgatgt
    33421 tgtctcatga agaagataaa ggtgtgcttt tagaattaaa ggggcgaggt tgccgacaat
    33481 ttgaaacttt tttactcgct caaaagcgta gctggtacga ctttttcgag gattgtctaa
    33541 aggccggtgg cgtgatgaaa cgcttggact tggcaatcaa tgatcgagtg gggctattgg
    33601 atatacctga gctaacgaaa aaatgtcaga aggaagaatg tatctccttg tttcgtacct
    33661 ttaaaagtta tcgttccggg gaacttttaa aggctgatga aaaggacggc atgggcaata
    33721 ccttatatat cggcagtctc aagagtgagg tttatttctg tttgtatgaa aaagactatg
    33781 aacaatatat caagttaggg attccattag accaaactga gacgaaaaat cgttttgaga
    33841 ttcgactgaa aaatgaccgt gcttttcatg cgattcaaga tttgttaaaa ggtcgtagca
    33901 ttgagagcac cacgttttcc attatcaatc gttacttgcg atttgcggat aaagtagaag
    33961 gtaaaaggcg aaccaactgg cccttgaatg aacaatgggg gcgttttatt ggacggaatc
    34021 ggaaagagat tcaattaact tccgagccaa aaccgtatac cattgaacga accttgaatt
    34081 ggctaggccg acaagtcgcc cctacgtgga aaatggctaa ggagttggat cgattgaatc
    34141 ggacaaccta tatccaggat atggtacaga atgcacgctt atcagaccga cataaaaaga
    34201 ttttggagca acaaagtatg gcaattgaaa atttgattat atgaaaagag gaatcgtcat
    34261 gggaattgta aaagatattt ttttggtatt tggtggcagt atgcttggtg ttactgtgat
    34321 gtgcttgatg aatgcaagtg cagcagcgga tcgagcaatg gaaaagaaag gaaagtgaca
    34381 agatgaattt cggacaaaat ttatgtgcga ctcgttcctt agtgaaaagc taaggcacta
    34441 ataaaagaac gaaaaagttt ggttattagg agaactgata atctgacagg tggaatgatg
    34501 aagtaacgct ctgaaacgcc tgccctgagc ctccgacaag cattgtatga ggaaactcag
    34561 aatgtttgaa gctcggtaaa gacggctgaa agataccgta atagttgatg aacatatatc
    34621 ttctatcgaa aactatccag aggtgggtag cgtatccaac aggtcggggg tctataaaat
    34681 atctatggtt agaatgttct ataaggaact gacgaaacag cgaatgtacg ggtctaaatt
    34741 tgaactttgt agaaatgcaa aggtacgaga aatcgtagct ggtgtggcaa agtaagaata
    34801 taggttatga aatgccatat aacgttacag gcggtatcaa gccagcaggc ttatagctag
    34861 tgacctaagg atatatatgt atagataaga ttatcggaac gaggaaaggt attgggttct
    34921 catcaagaga ataaactgac gaagaacaat aagcagttga actaatgctg aaaagcagag
    34981 ggcgaaccta agaaattctt gtaatgagaa tggaggaatg ccctcaagtc gtgtatatat
    35041 tagaaaagta ttatgttgtt tcaataagga ttacgagtaa gataaaaaag ctcactcaat
    35101 ttcaagtaaa ggagtgaagc cttatgccta aaaataaaaa tgaaacattg tgtgtagaag
    35161 atttaagaca cgctgaatat tacgaaatgc aaaacacctt tgatgattta tatgccaaaa
    35221 gtaagaatgg agatattttc actcatctta tggatattat cctatcgaga gaaaatatat
    35281 tactggcata tcgaaatatc aaagcaaatg caggcagtaa aacagcagga acagacggta
    35341 caataattaa agatattggc aaattgccag cagaaacagt tgtcaaaaaa gtaagataca
    35401 ttgttgcagg cagtccacat gggtatcgac ctaagccagt gaggcgaaaa gaaataccaa
    35461 aaccaaatgg taaaaccaga cctctaggta ttccttgtat gtgggacagg cttatacaac
    35521 aatgtataaa acaagtatta gaaccaatct gcgaagctaa atttagtgaa aacagctatg
    35581 gttttagacc taataggtca gttgaaaatg caataaaagc aacctataac cgcctacaaa
    35641 tcagccagct acattatgtg attgaatttg atattaaggg tttctttgac aacgtgaacc
    35701 attccaagct gataaaacag atatgggcta tgggaatacg ggacaagcac ttgatattca
    35761 ttttaaaaag gatattaaaa gctccaatca aaatgactaa cggtacaata acatatccag
    35821 agaaaggaac tccgcaaggg ggaataatat ccccactact agcaaacatt gttcttaatg
    35881 agttagacca ttgggtagaa agccaatggc aggaaaatcc tgttacaaaa aactatgtgg
    35941 ttcatatcaa taaaagcggt agcccatgta aaagcaacgc ttacaaagaa atgaagaaaa
    36001 caaagttaaa ggaaatgtat atggttcgtt atgcagatga ttttagagtt ttctgccgct
    36061 acaaggaaag tgctgaaaaa gccaaaatag caatcactca atggattgaa caacgattaa
    36121 aattggaagt atcacaagaa aaaacaagaa ttgtaaatgt tagaaaaaga tactccgact
    36181 ttcttggttt caagattaaa atgataccga gaagaaagaa gttagttgtt aaatcacata
    36241 taagtgataa acaattcaaa aaccaaaaag acaagctggt atcacaggca aagaaaattg
    36301 cttctccctc aaaagggaaa acggaattag aagaaacaag actttataat tcaatggtat
    36361 taggtatgca aaattattat cagattgcaa cgaatgtaaa tctggattgt atgaaactga
    36421 atagagctgt aatggctatc ttcactaaca gattaggtac aaacaaaagg ggcagattga
    36481 gaaaaacagg cagacaactt acgacaaagg aggcaacaag atatggtaaa tctaaaatgc
    36541 ttcggtatgt tgctggcgag ggcgaaccta ttttccctgt tggatatatc caacacagaa
    36601 aaccaatggc aaaggtgtat ttagcgaatt gctacactct agagggaaga aaatttatcc
    36661 acaccaatct aagtgttgat aaattactga tgtaccagtt aatgaaatta tctttggaaa
    36721 atcgcacaat agaatacgca gacaatcgaa tttcgctatt ttctgctcaa catggaaaat
    36781 gtgctataac tctggaagaa tttcaacaag ctaatgaaat acattgtcat catattgtac
    36841 caactggagc tggtggaaat gacgattata aaaatcttat tttggtaaaa gaggcggtac
    36901 accgtctaat acacgctaaa acagaagaaa caatacaaaa atatatagct ctattgaagc
    36961 taaataaagt ccagctcata agactaaata aatatagagt attagctggc aatcaagaat
    37021 taaacttgat ataggtctac tacataaata cttttcaata taaacacgat ggaacgcgga
    37081 gtgcggtgaa agtcgcacgc tccgtgtgaa tggggggaaa agtttgagat atttataata
    37141 tcaggaactt acctatccat atataactgg tttctatcaa acgctcaatc actggtgctt
    37201 ttagcaatcg ttgtgattgg cttgtatctt ggcttcaagc gtgagtttag caaactgatt
    37261 ggctttttaa ttattgcgat tattgcggtt ggcttagtct tcaacgctgc tggagtaaaa
    37321 gacattttac tagagctatt caatcgcatt attggtgctt aaataaaacc gttcttttgt
    37381 ggaatataag tggttttctt atgttccgca aaggaatggt acaccaaacg aagtgcggta
    37441 gggatttttg aatctctaca aagaaaggac gtgaatatat ggacgatatg caagtctata
    37501 ttgcgaattt aggcaaatac aatgagggcg aattggtcgg tgcgtggttt acctttccca
    37561 ttgactttga ggaagtcaaa gagaaaatcg gcttgaatga tgaatatgag gaatacgcca
    37621 ttcatgatta cgagttaccc tttacggttg acgaatacac ttctattagc gaactcaatc
    37681 gcctatggga aatggtatcg gagttgccag aagaactaca atcggagcta tctgctctgc
    37741 tcactcattt ttcaagtatt gaagaactaa gcgaacatca agaagatatt atcattcatt
    37801 ccgattgtga tgatatgtct gacgtggcac gctactacat tgaagaaacg ggtgctttag
    37861 gcgaagtgcc agccagtctt caaaactata ttgattatga atcctatggt cgggatttag
    37921 acctttcggg aacgtttatc tcaaccaatc acgggatttt tgaaatcgtc tattaaatct
    37981 gtcggtacat tcttactggc agattttctt gtttacgggg tagtcaaaag actatcccca
    38041 tttttatgaa aggattgatt acatgaagaa aatacgaagc tataccagta tctggtctgt
    38101 tgagaaagtg ttgtactcca tcaatgactt tagacttccg tttcccataa cctttacgca
    38161 aatgacatgg tttgtcgtgt cactctttgc agttatgata cttggcaact tgccccctct
    38221 ttctatgata gagggagcat ttctcaaata ctttgggatt cctgtggctt tcacatggtt
    38281 tatgtctaca aaaacctttg atggtaaaaa gccttatgga tttttgaagt ctgtcattgc
    38341 ttatgcactg cgacgaaagc tgacctatgc aggaaaaaaa gtaacgcttg gcagaaacca
    38401 gccacaagaa gccattacag cagttaggag tgaattttat ggcatatcca attaaatata
    38461 ttgaaaacaa tctggtctgg aataaagatg gggaatgtta cgcttactat gagcttgttc
    38521 cctacaatta ctcatttcta agtccggaac agaaaataca agtacatgat tctttcagac
    38581 agcttatcgc acaaaatcgt gatggcaaga ttcatgcttt acaaatcagt acagaatcca
    38641 gcatactttc tgcacaagaa cgttccaaaa atgaagtcac tggaaagctc aaaacggttg
    38701 cctatgacaa aatcgaccaa cagacagacg ctttaatatc catgattggc gaaaatcaag
    38761 tggactaccg tttctttatc ggttttaagt tgcttctcaa cgatcaggag ttttctatga
    38821 aaagtcttac cgttgaagca aaaaatgctt ttactgattt tgtctatgat gtgaaccata
    38881 agctgatggg cgattttgtt agtatgagta atgatgaaat cctgcgtttt cagaagatgg
    38941 aaaagctttt agaaaataaa atctcccgtc gtttcaaaat ccgaagatta gataaggatg
    39001 acttcggcta tctgattgaa cacctttacg gacagacagg cactgcctat gaagagtatg
    39061 agtatcctct atcaaagaaa aagctggaac atgaaacact gattaaaacc tatgacctca
    39121 ttaagcctac tcgctgtctg gtggaagaaa aacagcgata tttgaaaatc cagcaggaag
    39181 acgaaaccgc ctatgtagct tactttacca tcaacagtat tgtcggcgaa ctggacttcc
    39241 cgtcctctga aatcttctac taccagcaac agcaatttac ctttccgatt gatacgtcaa
    39301 tgaatgtgga aattgtagcg aatcgtaaag ccctatctac tgtccgcaat aaaaagaaag
    39361 aactgaaaga cttggataac cacgcttggc aaagtgataa tgaaaccagc tctaatgtgg
    39421 cggaagctct ggaaagtgtg aacgagctgg aaaccaattt agaccaaagc aaggaatcta
    39481 tgtataagct gtcctatgtt gtaagggtat cagcaaatga ccttgacgaa cttaaacgtc
    39541 gttgtaatga agtgaaagat ttctatgatg atttgagcgt gaaactggta cgaccttttg
    39601 gggatatgct gggcttacat gaagaatttt tacctgccag caaaagatat atgaatgact
    39661 atattcaata cgtgacctct gatttcctcg ctggtttagg ttttggtgct actcaaatgc
    39721 tgggtgaaaa tgaggggatt tatgttggct acagcttaga tactggacgc aatgtctatc
    39781 tgaaacctgc tcttgccagt caaggggtta agggttcagt aaccaatgcg ttagcgtctg
    39841 cctttgtcgg ttcgctgggt ggtggtaaat cctttgcgaa taaccttatc gtctattatg
    39901 cagtgcttta tggggcacaa gcagtgattg tagacccaaa agcagaacgt ggcagatgga
    39961 aagaaacctt gccagagatt tcccatgaaa tcaatatcgt caatctgact tctgatgaga
    40021 aaaacaaagg cttacttgac ccttatgtaa ttatgaaaaa taccaaagat tctgaatcac
    40081 tggctattga tattttgaca ttccttacgg ggatttcctc tcgtgatggg gaacgcttcc
    40141 caatccttag aaaagccatt cgtgcagtaa ccaatagtga agtgcgaggg ttgatgaaag
    40201 tgattgaaga attacgggtt gagaatacgc cactaagtac cagcatagcc gaccatatcg
    40261 aaagttttac agactatgac tttgcccatc tgctttttag tgatggttat gtagagcagt
    40321 ctatcagcct tgaaaaacaa ctgaacatta tacaggttgc cgacttggta cttcctgaca
    40381 aggaaacttc ctttgaggaa tataccacaa tggagttact atcggtagca atgctgattg
    40441 tcattagtac ctttgcgttg gactttatcc atacagaccg aagtattttc aagattgtag
    40501 acttagacga agcatggagc ttcttacagg tggcacaagg gaaaacacta tctatgaagc
    40561 tggttcgtgc tggtcgtgct atgaacgctg gggtatattt cgtgacccaa aatacagatg
    40621 acctcttaga tgaaaaactg aaaaataacc tcggcttaaa atttgccttt cgttccactg
    40681 accttaacga gattaaaaaa acccttgcct tttttggtgt agacccagag gacgaaaaca
    40741 atcagaagcg attgcgtgat ttggaaaacg ggcaatgcct tatcagtgat ttatatggtc
    40801 gtgtcggtgt gatacagttc caccctgtat ttgaagaact gctccatgcc tttgatacca
    40861 gaccacctgt gcgaaaagag gtgtaaatgt gaaaccatca atattaaaca gaataaaatc
    40921 aaactggacg ctgaaacgtc taggtaaagt ggcaatgaca gtggctttca cacttgtgat
    40981 tgccattttt cttttagcca tgctgggaac ggtggttcaa gctgcgggct tggtagatga
    41041 tacggtcaat gtggcaaatg aatacagccg atacccactt gaaaactatc aactggattt
    41101 ttatgtggat aatagctggg gctggctacc gtggaactgg tcggacggaa ttggaaaaca
    41161 agtcatgtat ggactatatg ccattaccaa ttttatttgg acaatcagtc tttatgtttc
    41221 caatgcgacg ggttacttag tacaggaagc ctattcctta gacttcattt ccgctacagc
    41281 agattccatt ggcaagaata tgcagaccct tgcaggggtt acgcctagtg gactatcaac
    41341 agagggtttc tatgttggat tccttttact cttgattttg gttcttgggg tttatgttgc
    41401 ctatacagga ctgataaaga gagaaaccac aaaggcaatt catgccctca tgaattttgt
    41461 gctggttttt atcctatcgg cttcctttat tgcctacgct cccgactaca ttaaaaaaat
    41521 caatgacttt tcatcagaca tcagcaacgc tagtttgtca ctgggtacaa aaattgtcat
    41581 gccccattca gatagtcaag gcaaggacag tgtggacttg atacgtgaca gcctattttc
    41641 catacaggtt cagcaaccgt ggctactgct tcaatataac agttcagaca ttgaaagtat
    41701 tggtattgac cgtgtggaaa gcctgctctc aaccagtcca gattccaaca atggggaaga
    41761 cagagaaaaa attgttgcgg aagaaattga agatagaagc aataccaata tgacgattac
    41821 aaagacgatt aaccgtttag gtacagtctt cttcctattt gtcttcaata ttgggatttc
    41881 catatttgta ttcctattaa caggaatcat gattttctcg caggtacttt ttatcatcta
    41941 tgctatgttt ctgcctgtga gctttatttt aagcatgatt ccatcatttg atggtatgtc
    42001 aaaacgagcc ataacaaagc tctttaatac cattttgaca cgagctggaa tcacattgat
    42061 tattacgaca gcatttagta tttcaaccat gctctatacc ttatcggctg gttatccgtt
    42121 ctttttgatt gcttttctac agattgtgac ctttgcagga atctacttta agctgggcga
    42181 tttaatgagt atgttttctc tacagagtaa cgattctcaa agtgtgggaa gtcgtatgat
    42241 gagaaaacct cgtatgctta tgcacgctca catgcaccgt ctacagcgga aacttggacg
    42301 ctccgtgact gctttagggg ctgggtctgc cattgccagt gctacgggta aaaaaggaca
    42361 gtcgggttcg ggaagttctg cgagtacaca agcagatcac tctcgaccaa acgggcagga
    42421 aaaatcaaca ctaggaaagc gtatcggtca aaccatcggt acagtagctg ataccaaaga
    42481 cagaatggta gatactgctg gtaatttgaa agaacaggtt aaggatttgc cgaccaatgc
    42541 aagatatgca gtatatcaag gaaaatctaa agtgacggat aatgtccatg atttaaccag
    42601 aagtatttct caaaccaaag cggataaagc cagtggacgc aagaaacagc aggaacaaag
    42661 acggaaaacc attgcggagc gtcgctctga aatggaacag gtcaaacaga aaaaacagcc
    42721 agcttcttcc gttcatgaaa gaccagccac taagcaagaa caatctcatg atggacagac
    42781 ttcaaggcaa acaactgtac aggcttccta tagggaatct caacaagcca aacaagagcg
    42841 tccaacagtt aagtccgatt cttcaagttt aaaaacggaa cgtcaaagta atacagttca
    42901 agaaagaacg gttcaaaagc cagtaacttc aactgcacca acagatagag cttcacaacg
    42961 ttcaatcaca aaagaacgtc agtctactgt tcaaagagta ccactacaaa atacaaaaag
    43021 tagaccacca atcaaaaccg ccaccattaa gaaaggcagt aagaaaccat gaagctgaaa
    43081 actttagtga ttggtggttc gggattattc ttgatggtct tctcactgct tctgtttgtc
    43141 gccattttat tttcagatga acaagatggc ggtttttcca acattcacta tggcggtgtg
    43201 gatgtttccg cagaagtgct ggctcataag cctatggtag aaaaagttgc caaagaatat
    43261 ggaattgaag aatacgtcaa tatacttctt gcgattatac aggtggaatc gggtggtaca
    43321 gcagaagatg ttatgcagtc ctcggaatcc ctcggtcttc cacctaattc attgagtaca
    43381 gaagaatcca ttaagcaagg tgtgaagtat ttcagtgagt tattagccag tagcgaaagg
    43441 cttggtgtag atttagaatc ggttatccag tcctacaatt atggtggtgg tttcttagga
    43501 tatgtggcta atcgtgggaa taaatatacc tttgaactgg ctcaaagttt ctcaaaagag
    43561 tattcgggtg acgaaaaagt gtcttacccc aatcccatag ccatacctat caatgggggc
    43621 tggcgataca attacgggaa tatgttttat gtgcaactgg taacgcagta tcttgtcaca
    43681 acagagtttg atgatgatac agtacaagcc atcatggacg aagctctgaa atttgaaggc
    43741 tggaagtatg tctatggcgg agcttccccg actacctctt ttgattgtag cggactgaca
    43801 caatggacgt atggaaaagc tggaatcaac ttaccacgaa cagcacaaca gcaatatgat
    43861 gtaacccggc atatcccatt attggaagca aaagccggcg atttggtttt ctttcattct
    43921 acctataacg ctggctctta tattactcat atcgggattt atttaggcga taaccgtatg
    43981 tttcatgcag gcgaccctat cggttatgcc gacttaacaa gctcttactg gcaacagcat
    44041 ttagtgggag caggacgaat caaacaataa gaaaggacga ttcaatgatg aaattcggaa
    44101 aaaatcagaa tacagaaaaa cagacaccaa aggaaaagaa acctcgtgtc tataaggtca
    44161 atcctcgtaa aaaggttgtg attgtcctat gggtactttt aggacttagt ttcagctttg
    44221 cgatattcaa gcactttaca gccattgata cccataccat tcatgaaacc accatcatag
    44281 aaaaggaata tgtcgatact catcatgtgg aaaattttgt agagaacttt gcgaaagtct
    44341 actattcatg ggaactaaac gacaagtcca ttgataatcg catagaaaac ctgaaagcat
    44401 atctgacaga ggaacttcaa gctctgaatg tcgatacagt tcgtaaagat attcctgtat
    44461 cgtcttctgt aaaaggattt cagatatgga cggtagaagc agatggcgac aatcaatttg
    44521 atgtaaccta cagtgtagac caactcatta cagaggggga aaatacaaag accgtccact
    44581 ctgcttatat agtgagtgtc tatgtagaca gtactggaaa tatggtcctc attaagaatc
    44641 cgaccattac tagcatacca aagaaatcag actataaacc aaaagctatt gaaagtgagg
    44701 gtacggttga ttccattaca accaatgaaa tcaatgagtt tttaacgacg ttcttcaagc
    44761 tctatcctac agcgacagcc agtgaacttt cctactatgt gaatgacggg atattaaaac
    44821 caatcggaaa agagtacatc tttcaagaac tggtaaatcc tatttacaat cgtaaggata
    44881 atcaagtcac ggtatcgctg acagtggagt atatcgacca gcagaccaaa gcaacgcagg
    44941 tatctcaatt tgatttggta cttgaaaaga acgggagtaa ttggaagatt atagaataac
    45001 aaatattggt acattattac agctattttg taatcacgta ctctctttga taaaaaattg
    45061 gagattcctt tacaaatatg ctcttacgtg ctattattta agtatctatt taaaaggagt
    45121 taataaatat gcggcaaggt attcttaaat aaactgtcaa tttgatagtg ggaacaaata
    45181 attggatgtc cttttttagg agggcttagt tttttgcacc cagtttaaga atacctttat
    45241 catgtgattc taaagtatcc ggagaatatc tgtatgcttt gtatgcctat ggttatgcat
    45301 aaaaatccca gtgataagag tatttatcac tgggattttt atgccctttt gggcttttga
    45361 atggaggaaa atcacatgaa aattattaat attggagttt tagctcatgt tgatgcggga
    45421 aaaactacct taacagaaag cttattatat aacagtggag cgattacaga attaggaagc
    45481 gtggacaaag gtacaacgag gacggataat acgcttttag aacgtcagag aggaattaca
    45541 attcagacag gaataacctc ttttcagtgg gaaaatacga aggtgaacat catagacacg
    45601 ccaggacata tggatttctt agcagaagta tatcgttcat tatcagtttt agatggggca
    45661 attctactga tttctgcaaa agatggcgta caagcacaaa ctcgtatatt atttcatgca
    45721 cttaggaaaa tggggattcc cacaatcttt tttatcaata agattgacca aaatggaatt
    45781 gatttatcaa cggtttatca ggatattaaa gagaaacttt ctgccgaaat tgtaatcaaa
    45841 cagaaggtag aactgtatcc taatatgtgt gtgacgaact ttaccgaatc tgaacaatgg
    45901 gatacggtaa tagagggaaa cgatgacctt ttagagaaat atatgtccgg taaatcatta
    45961 gaagcattgg aactcgaaca agaggaaagc ataagatttc agaattgctc cttgtaccct
    46021 gtttatcatg gaagcgcaaa aagcaacata gggattgagc agcttataga agtgataacg
    46081 aataaatttt attcatcaac atacagaaag aagtctgaac tttgcggaaa tgtcttcaaa
    46141 attgaatatt cggaagaaag acaacgtctt gcatatgtac gcctttatgg cggaatcctg
    46201 catttgcggg attcggttag aatatcggaa aaggaaaaaa taaaaattac agaaatgtat
    46261 acttcaataa atggtgaatt atgtaaaatt gataaggctt attccgggga aattgttatt
    46321 ttgcaaaatg agtttttgaa gctaaatagt gttcttggag atacaaagct attgccacag
    46381 agagagagaa ttgaaaatcc gctccctctg ctgcaaacaa ctgttgaacc gagcaaacct
    46441 caacaaaggg aaatgttact tgatgcactt ttagaaatct ccgacagtga cccgcttcta
    46501 caatattatg tggattctac gacacatgaa attatacttt ctttcttagg gaaagtacaa
    46561 atggaagtga ttagtgcact gttgcaagaa aagtatcatg tggagataga actaaaagag
    46621 cctacagtca tttatatgga gagaccgtta aaaaatgcag aatataccat tcacatcgaa
    46681 gtgccgccaa atcctttctg ggcttccatt ggtttatctg tatcaccgct tccgttggga
    46741 agtggaatgc agtatgagag ctcggtttct cttggatact taaatcaatc atttcaaaat
    46801 gcagttatgg aagggatacg ctatggttgc gaacaaggat tatatggttg gaatgtgacg
    46861 gattgtaaaa tctgttttaa gtatggctta tactatagcc ctgttagtac cccagcagat
    46921 tttcggatgc ttgctcctat tgtattggaa caagtcttaa aaaaagctgg aacagaattg
    46981 ttagagccat atcttagttt taaaatttat gcgccacagg aatatctttc acgagcatac
    47041 aacgatgctc ctaaatattg tgcgaacatc gtagacactc aattgaaaaa taatgaggtc
    47101 attcttagtg gagaaatccc tgctcggtgt attcaagaat atcgtagtga tttaactttc
    47161 tttacaaatg gacgtagtgt ttgtttaaca gagttaaaag ggtaccatgt tactaccggt
    47221 gaacctgttt gccagccccg tcgtccaaat agtcggatag ataaagtacg atatatgttc
    47281 aataaaataa cttagtgtat tttatgttgt tatataaata tggtttcttg ttaaataaga
    47341 tgaaatattt tttaataaag atttgaatta aagtgtaaag gaggaattaa ttatgaagtg
    47401 taatgaatgt aacagggtta aatacaacca aattttaatt tggctttgcg ttttatcttt
    47461 ttttagcgta ttaaatgaaa tggttttgaa cgtctcatta cctgatattg caaatgattt
    47521 taataaacca cctgcgagta caaactgggt gaacacagcc tttatgttaa ccttttccat
    47581 tggaacagct gtatatggaa agctatctga tcaattaggc atcaaaaggt tactcctatt
    47641 tggaattata ataaattgtt tcgggtcggt aattgggttt gttggccatt ctttcttttc
    47701 cttacttatt atggctcgtt ttattcaagg ggctggtgca gctgcatttc cagcactcgt
    47761 aatggttgta gttgcgcgct atattccaaa ggaaaatagg ggtaaagcat ttggtcttat
    47821 tggatcgata gtagccatgg gagaaggagt cggtccagcg attggtggaa tgatagccca
    47881 ttatattcat tggtcctatc ttctactcat tcctatgata acaattatca ctgttccgtt
    47941 tcttatgaaa ttattaaaga aagaagtaag gataaaaggt cattttgata tcaaaggaat
    48001 tatactaatg tctgtaggca ttgtattttt tatgttgttt acaacatcat atagcatttc
    48061 ttttcttatc gttagcgtgc tgtcattcct gatatttgta aaacatatca ggaaagtaac
    48121 agatcctttt gttgatcccg gattagggaa aaatatacct tttatgattg gagttctttg
    48181 tgggggaatt atatttggaa cagtagcagg gtttgtctct atggttcctt atatgatgaa
    48241 agatgttcac cagctaagta ctgccgaaat cggaagtgta attattttcc ctggaacaat
    48301 gagtgtcatt attttcggct acattggtgg gatacttgtt gatagaagag gtcctttata
    48361 cgtgttaaac atcggagtta catttctttc tgttagcttt ttaactgctt cctttctttt
    48421 agaaacaaca tcatggttca tgacaattat aatcgtattt gttttaggtg ggctttcgtt
    48481 caccaaaaca gttatatcaa caattgtttc aagtagcttg aaacagcagg aagctggtgc
    48541 tggaatgagt ttgcttaact ttaccagctt tttatcagag ggaacaggta ttgcaattgt
    48601 aggtggttta ttatccatac ccttacttga tcaaaggttg ttacctatgg aagttgatca
    48661 gtcaacttat ctgtatagta atttgttatt acttttttca ggaatcattg tcattagttg
    48721 gctggttacc ttgaatgtat ataaacattc tcaaagggat ttctaaatcg ttaagggatc
    48781 aactttggga gagagttcaa aattgatcct ttttttataa caggaattca aatctttttg
    48841 ttccattaaa gggcgcgatt gctgaataaa agatacgaga gacctctctt gtatcttttt
    48901 tattttgagt ggttttgtcc gttacac
//
LOCUS       DAFKHN010000016        46219 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFKHN010000016 DAFKHN010000000
VERSION     DAFKHN010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 46219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.016"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            160..840
                     /locus_tag="LY912_000870"
     CDS             160..840
                     /locus_tag="LY912_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBM6954581.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="LY912_000871"
     CDS             930..1964
                     /locus_tag="LY912_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBM6954582.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="LY912_000872"
     CDS             1978..2313
                     /locus_tag="LY912_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954583.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="LY912_000873"
     CDS             2297..4777
                     /locus_tag="LY912_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954584.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPTAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="LY912_000874"
     CDS             4833..6392
                     /locus_tag="LY912_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6954585.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="LY912_000875"
     CDS             6389..7753
                     /locus_tag="LY912_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBM6954586.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="LY912_000876"
     CDS             7924..8994
                     /locus_tag="LY912_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954587.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="LY912_000877"
     CDS             9009..9677
                     /locus_tag="LY912_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954588.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="LY912_000878"
     CDS             9697..10275
                     /locus_tag="LY912_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6954589.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="LY912_000879"
     CDS             10676..11587
                     /locus_tag="LY912_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBM6954590.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="LY912_000880"
     CDS             complement(11965..12882)
                     /locus_tag="LY912_000880"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBM6954591.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="LY912_000881"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="LY912_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBM6954592.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="LY912_000882"
     CDS             13579..14127
                     /locus_tag="LY912_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBM6954593.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="LY912_000883"
     CDS             14242..16602
                     /locus_tag="LY912_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBM6954594.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="LY912_000884"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="LY912_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBM6954595.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="LY912_000885"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="LY912_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBM6954596.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="LY912_000886"
     CDS             19108..20007
                     /locus_tag="LY912_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954597.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="LY912_000887"
     CDS             20000..21262
                     /locus_tag="LY912_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954598.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="LY912_000888"
     CDS             21423..23321
                     /locus_tag="LY912_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBM6954599.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="LY912_000889"
     CDS             complement(23651..24370)
                     /locus_tag="LY912_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBM6954600.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            24707..25039
                     /locus_tag="LY912_000890"
     CDS             24707..25039
                     /locus_tag="LY912_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954601.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="LY912_000891"
     CDS             25026..27029
                     /locus_tag="LY912_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBM6954602.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="LY912_000892"
     CDS             27048..27518
                     /locus_tag="LY912_000892"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBM6954603.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="LY912_000893"
     CDS             27539..28123
                     /locus_tag="LY912_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBM6954604.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="LY912_000894"
     CDS             28138..29124
                     /locus_tag="LY912_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBM6954605.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="LY912_000895"
     CDS             29114..29425
                     /locus_tag="LY912_000895"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBM6954606.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="LY912_000896"
     CDS             29447..31228
                     /locus_tag="LY912_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBM6954607.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="LY912_000897"
     CDS             31221..32597
                     /locus_tag="LY912_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBM6954608.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="LY912_000898"
     CDS             32604..33239
                     /locus_tag="LY912_000898"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBM6954609.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="LY912_000899"
     CDS             33269..34624
                     /locus_tag="LY912_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBM6954610.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="LY912_000900"
     CDS             complement(34816..36210)
                     /locus_tag="LY912_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBM6954611.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="LY912_000901"
     CDS             36302..37273
                     /locus_tag="LY912_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBM6954612.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="LY912_000902"
     CDS             37270..38052
                     /locus_tag="LY912_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBM6954613.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="LY912_000903"
     CDS             complement(38221..38592)
                     /locus_tag="LY912_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBM6954614.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="LY912_000904"
     CDS             38726..39169
                     /locus_tag="LY912_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBM6954615.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="LY912_000905"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="LY912_000905"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBM6954616.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="LY912_000906"
     CDS             complement(40040..41407)
                     /locus_tag="LY912_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBM6954617.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="LY912_000907"
     CDS             complement(41391..42221)
                     /locus_tag="LY912_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBM6954618.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="LY912_000908"
     CDS             42384..42821
                     /locus_tag="LY912_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBM6954619.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /locus_tag="LY912_000909"
     CDS             42897..43517
                     /locus_tag="LY912_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBM6954620.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43706..44212
                     /locus_tag="LY912_000910"
     CDS             43706..44212
                     /locus_tag="LY912_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBM6954621.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44229..45128
                     /locus_tag="LY912_000911"
     CDS             44229..45128
                     /locus_tag="LY912_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBM6954622.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45215..46099
                     /locus_tag="LY912_000912"
     CDS             45215..46099
                     /locus_tag="LY912_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBM6954623.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
BASE COUNT        15237 a         7977 c         9765 g        13240 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccaac tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc
    43621 ccaagtaaat acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat
    43681 taagtgaggc agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat
    43741 cgaaaaatac cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg
    43801 tatcacgatg aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt
    43861 tcataaagcc ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt
    43921 ttatcggata ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt
    43981 ggacttattt gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga
    44041 gctccatatg attttagata aaatagacag tccggaaaaa gagattctga tcctctactt
    44101 ttttgaagga tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt
    44161 taaaacgaaa atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga
    44221 agagtgccat gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac
    44281 aagcaattcc caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat
    44341 catttataaa agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta
    44401 tcgtaatgat tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag
    44461 atttacccat cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat
    44521 ctgaaaaaat cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa
    44581 caattcatgg attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg
    44641 aaaaagaata tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa
    44701 tcgtagacga taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata
    44761 gccatgttga aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc
    44821 cacttttatt caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga
    44881 tggccgaaca agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag
    44941 aagggacgat agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag
    45001 agcatcaatt agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac
    45061 cagaatttgt cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg
    45121 atcattagac gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa
    45181 taataagaag agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag
    45241 tattattgct ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac
    45301 cgaagtaaaa ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga
    45361 acaatcaacc attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga
    45421 atcagcggaa aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag
    45481 ccgagatccg gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac
    45541 aacaccgcag cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt
    45601 aggagaaaat acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga
    45661 gattggcaat cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac
    45721 ggaggaagtg acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt
    45781 tgttcgtccg ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat
    45841 catcgaatgg tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca
    45901 gaagatccaa gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga
    45961 aacgattcgt gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac
    46021 gacagttggg gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga
    46081 tcatcggcca gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt
    46141 agttgaacac ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa
    46201 aaaactgtcc accaatttt
//
LOCUS       DAFKHN010000017        44859 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFKHN010000017 DAFKHN010000000
VERSION     DAFKHN010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.017"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            212..604
                     /locus_tag="LY912_000913"
     CDS             212..604
                     /locus_tag="LY912_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBM6954624.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="LY912_000914"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="LY912_000914"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBM6954625.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="LY912_000915"
     CDS             3165..4775
                     /locus_tag="LY912_000915"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBM6954626.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="LY912_000916"
     CDS             5067..5936
                     /locus_tag="LY912_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBM6954627.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="LY912_000917"
     CDS             6101..7372
                     /locus_tag="LY912_000917"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBM6954628.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="LY912_000918"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="LY912_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBM6954629.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="LY912_000919"
     CDS             8763..9026
                     /locus_tag="LY912_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBM6954630.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="LY912_000920"
     CDS             9471..9920
                     /locus_tag="LY912_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6954631.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="LY912_000921"
     CDS             9977..11395
                     /locus_tag="LY912_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBM6954632.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="LY912_000922"
     CDS             11395..12255
                     /locus_tag="LY912_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBM6954633.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="LY912_000923"
     CDS             12429..13202
                     /locus_tag="LY912_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBM6954634.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="LY912_000924"
     CDS             13349..13714
                     /locus_tag="LY912_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBM6954635.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="LY912_000925"
     CDS             complement(13862..15070)
                     /locus_tag="LY912_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6954636.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="LY912_000926"
     CDS             complement(15089..15367)
                     /locus_tag="LY912_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954637.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="LY912_000927"
     CDS             15521..16216
                     /locus_tag="LY912_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBM6954638.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="LY912_000928"
     CDS             complement(16658..17455)
                     /locus_tag="LY912_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBM6954639.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="LY912_000929"
     CDS             complement(17452..18636)
                     /locus_tag="LY912_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBM6954640.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="LY912_000930"
     CDS             complement(18661..19908)
                     /locus_tag="LY912_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBM6954641.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="LY912_000931"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="LY912_000931"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBM6954642.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="LY912_000932"
     CDS             21888..22202
                     /locus_tag="LY912_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBM6954643.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="LY912_000933"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="LY912_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBM6954644.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="LY912_000934"
     CDS             22887..23531
                     /locus_tag="LY912_000934"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBM6954645.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="LY912_000935"
     CDS             23546..23875
                     /locus_tag="LY912_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBM6954646.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="LY912_000936"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="LY912_000936"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBM6954647.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="LY912_000937"
     CDS             24863..25687
                     /locus_tag="LY912_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBM6954648.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="LY912_000938"
     CDS             25680..26027
                     /locus_tag="LY912_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBM6954649.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="LY912_000939"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="LY912_000939"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBM6954650.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="LY912_000940"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="LY912_000940"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBM6954651.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="LY912_000941"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="LY912_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBM6954652.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="LY912_000942"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="LY912_000942"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBM6954653.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="LY912_000943"
     CDS             31657..32451
                     /locus_tag="LY912_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954654.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="LY912_000944"
     CDS             32441..34483
                     /locus_tag="LY912_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954655.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="LY912_000945"
     CDS             34764..34913
                     /locus_tag="LY912_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBM6954656.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="LY912_000946"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="LY912_000946"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBM6954657.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="LY912_000947"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="LY912_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBM6954658.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="LY912_000948"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="LY912_000948"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBM6954659.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="LY912_000949"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="LY912_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBM6954660.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHCIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="LY912_000950"
     CDS             39330..40412
                     /locus_tag="LY912_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBM6954661.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="LY912_000951"
     CDS             40412..41215
                     /locus_tag="LY912_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBM6954662.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="LY912_000952"
     CDS             41285..42025
                     /locus_tag="LY912_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBM6954663.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="LY912_000953"
     CDS             42036..43040
                     /locus_tag="LY912_000953"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBM6954664.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44782)
                     /locus_tag="LY912_000954"
     CDS             complement(43085..44782)
                     /locus_tag="LY912_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954665.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14421 a         7825 c         9341 g        13272 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgattt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatt gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataa
//
LOCUS       DAFKHN010000018        43168 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFKHN010000018 DAFKHN010000000
VERSION     DAFKHN010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.018"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            591..1280
                     /locus_tag="LY912_000955"
     CDS             591..1280
                     /locus_tag="LY912_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6954666.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="LY912_000956"
     CDS             1267..2475
                     /locus_tag="LY912_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBM6954667.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="LY912_000957"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="LY912_000957"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBM6954668.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="LY912_000958"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="LY912_000958"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBM6954669.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="LY912_000959"
     CDS             complement(6578..7273)
                     /locus_tag="LY912_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBM6954670.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="LY912_000960"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="LY912_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBM6954671.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="LY912_000961"
     CDS             complement(8472..8663)
                     /locus_tag="LY912_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBM6954672.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="LY912_000962"
     CDS             complement(8684..9574)
                     /locus_tag="LY912_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBM6954673.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="LY912_000963"
     CDS             complement(9561..10328)
                     /locus_tag="LY912_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBM6954674.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="LY912_000964"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="LY912_000964"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBM6954675.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="LY912_000965"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="LY912_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBM6954676.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="LY912_000966"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="LY912_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBM6954677.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="LY912_000967"
     CDS             14899..15282
                     /locus_tag="LY912_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954678.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="LY912_000968"
     CDS             complement(15450..16208)
                     /locus_tag="LY912_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBM6954679.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="LY912_000969"
     CDS             complement(16226..17044)
                     /locus_tag="LY912_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBM6954680.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="LY912_000970"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="LY912_000970"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBM6954681.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="LY912_000971"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="LY912_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBM6954682.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="LY912_000972"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="LY912_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBM6954683.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="LY912_000973"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="LY912_000973"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBM6954684.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="LY912_000974"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="LY912_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBM6954685.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="LY912_000975"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="LY912_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBM6954686.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="LY912_000976"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="LY912_000976"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBM6954687.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="LY912_000977"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="LY912_000977"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBM6954688.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="LY912_000978"
     CDS             27086..27385
                     /locus_tag="LY912_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBM6954689.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="LY912_000979"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="LY912_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBM6954690.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="LY912_000980"
     CDS             27973..28209
                     /locus_tag="LY912_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBM6954691.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="LY912_000981"
     CDS             28352..30325
                     /locus_tag="LY912_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBM6954692.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGRFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="LY912_000982"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="LY912_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBM6954693.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="LY912_000983"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="LY912_000983"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBM6954694.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="LY912_000984"
     CDS             33204..34496
                     /locus_tag="LY912_000984"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBM6954695.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35283..36146
                     /locus_tag="LY912_000985"
     CDS             35283..36146
                     /locus_tag="LY912_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBM6954696.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36275..37897)
                     /locus_tag="LY912_000986"
     CDS             complement(36275..37897)
                     /locus_tag="LY912_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6954697.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38146..38667
                     /locus_tag="LY912_000987"
     CDS             38146..38667
                     /locus_tag="LY912_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBM6954698.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38853..40583)
                     /gene="spxB"
                     /locus_tag="LY912_000988"
     CDS             complement(38853..40583)
                     /gene="spxB"
                     /locus_tag="LY912_000988"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBM6954699.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40748..41566
                     /locus_tag="LY912_000989"
     CDS             40748..41566
                     /locus_tag="LY912_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBM6954700.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41669..41866)
                     /locus_tag="LY912_000990"
     CDS             complement(41669..41866)
                     /locus_tag="LY912_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954701.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42035..42613
                     /locus_tag="LY912_000991"
     CDS             42035..42613
                     /locus_tag="LY912_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBM6954702.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42708..42845
                     /locus_tag="LY912_000992"
     CDS             42708..42845
                     /locus_tag="LY912_000992"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954703.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT        13123 a         8263 c         8524 g        13258 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacgcttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaacaa acggtgttca aaagcttgca tctacggcac taagcccaat cagatgaaaa
    34741 atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca gctttttcac
    34801 aacctctcca ctaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatattcaa
    34861 caaacatgag aagctgtttt ttgaaattgt tccttgtgac tcggagctaa acggcaggct
    34921 cacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct caaaaaacgg
    34981 caaaatatga ggaactattt tttccgtttt tttctctaat actcaggtca aaacgctgat
    35041 ttcacaacct ctgattcacg gtgttccaga agtagcttct acggaaataa gccgaaattt
    35101 cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctgaccactt
    35161 ctgtcacaac ctcttatttt gattagaact tgcgaaaata aaccggttaa agtgtgtcta
    35221 gcgcaagaga tttgctataa tagacgataa gggtaaaatg taacgagaag gggttgaaaa
    35281 atgtgtatca aattgtaaca gattcttgtt gtgatctgcc ataccatgta ttagcaaaag
    35341 aaaaagttga ttttttatca atgaatctcc aattgaatga tcaagagtta gtagatgacc
    35401 tcggaaagac attcaattat gaccgctaca tgaatcagct gaaaaatggt gcgatgccta
    35461 cgacatcaca aatcaatgtt ggccgatatt tagaattttt ccgttcttat gcggaaaaac
    35521 agattcctgt tttatatgtg gctttttcca gtggattaag cggctcttac agtagtgcgc
    35581 ttcaagcggt tgaattgctg aaggaagaat atgaagaccc tgagatctat gtttttgata
    35641 caaaagctgc aagtattggg gaagggcttt tagtattgga agctgtaaga ttgaaaaaag
    35701 aaggtaaaag catcgaagaa accctagagt ggctggaaag taattatttg aaagtccatt
    35761 catgggtaac agtagacgat ctgaaatatc tagaacgagg cggtaggatt tccaaagcaa
    35821 gtgctactct tggcagtcta ttgagtgtaa agcctattat tacggtggat aaagaaggaa
    35881 ggctgacgaa tgttgacaaa gttcgaggaa gaaacaagtc gatccagaca atcgtcaatg
    35941 agacggtaaa aacaatcgtt gcaccacttg atcaaatcgt ttatgtggct tacgctgggg
    36001 atctagagag cgcggagaag gcaaaacggc ttttggaaga gcagataaag atgaaagatg
    36061 tgaagcttta tcccttagga ccaacgatcg ccagtcacac aggctatggc tgtatcgcga
    36121 ttttttcgat gggaatcagt cgataaaagc agtaactcat tctgtaaaaa agcccagaaa
    36181 ttgattgtaa caaaaacagc gactcttaaa agatagatga gcatcctatc tcttagaggt
    36241 cgctgttttt ttatttttta agctaaatag gccattatgc ccataactcg ttcaattgtt
    36301 tttgaatatc tgcattttcc aaaaattcat catatgtcgt atcagctcga tcgatcacac
    36361 ctttatccga aacggcaatg atgcggtttg ccaatgtttg gataaattga tggtcatgtg
    36421 acgcaaataa gattgagcca gtaaatgcca tcaagccgtc attcaatgct gtgattgatt
    36481 ctaagtctaa atggttcgtt ggatcatcta atacaagtac gttagctttc gaaagcatca
    36541 tttttgaaag catgcaacgg actttctctc caccagataa aacattcact ggtttcaata
    36601 cttcttcacc agaaaacaac attcttccta agaagcttct taagaaggtg ttatcatctt
    36661 cttctttact tgcatattga cgcaaccagt ctaaaatcgt tagatcagta tcgaattctt
    36721 tcgttgtatc ctttggtaaa taagaattac ttgttgtcac accccaacgt actgttccag
    36781 tatctggcgt aatttcaccc atgataactt tgaatagcgt tgttgttgtt atatcatttt
    36841 ctgcgacgaa agcgaccttg tcttctttgc tcaaattaaa agatatatca tctaaaattt
    36901 tctttccatc aatcgttaca cttacatttt ctacctgcaa taagtcgttt ccaatctcac
    36961 gttcaggttt gaatccaacg aatggataac gtctagaaga aggttggata tcgtctaaag
    37021 taattttttc aagcattttt ttacgtgaag ttgcttgttt tgattttgat gcattcgcac
    37081 taaagcgggc aataaattct tggagttctt tgatttgttc ttcttttttg gcatttgcgt
    37141 ttgcttgaag tttagccgct agttgactag attccaacca aaaatcataa tttcctacat
    37201 aaagtttgat tttaccaaaa tctagatccg ccatatgtgt acatactttg ttcaaaaagt
    37261 gacggtcatg ggatacaacg atcacagtat tttcaaaatt gatcaaaaat tcttccagcc
    37321 aattgatcga ttggatatcc agaccgtttg ttggttcgtc tagcaaaaga acatcaggtt
    37381 taccaaatag tgtttgtgct aataacactt ttaccttttg tccaccagtt aattcactca
    37441 tttgctgatg gtgcaattct tcagggatgt tcagaccttg cagtaaaaca gctgcttctg
    37501 gttcagcttc ccatccatta agctcagcaa attctccttc taattcagct gctcgaatac
    37561 catcttcgtc agtgaaatcc tctttcatgt aaatcgcatc tttttctttc agcacttcat
    37621 acagacgctt gtgtcccatg atgactgttt caagtacagt atagtcttca tagtcgtaat
    37681 ggttctgttt caatacggcc atccgttcat ctggtcccat agtaacggaa cctgtggaag
    37741 gctgcagatc ccctgataac actttaagga acgttgattt acctgcacca tttgcaccaa
    37801 tcaagccata gcagtttccg ggggtaaatt taatattcac atcatcaaat agtttgcggt
    37861 ctgaaaagtg caaactcaca tcatttacag taatcaattt ttttcctcac ttttatcatt
    37921 attagttttg acaagtctta tagaattata taggggaaag gtaaaagatt caaggcaatc
    37981 gaacattctt tgtgtttcac gtgaaacaga atgaaaaaaa taaaaataaa agcggagcga
    38041 aaatagctac tataggattt attagtttgc aacagcataa tttttgacgt tatttataag
    38101 agggagtact ataaaactgt aaaagaaatg aaagaaggat tgaaaatgga tgaaaaaaga
    38161 accatcgact ggggctcatt gattttggga attttatttg tacttgtctc attgttatca
    38221 tttcaagacc ctgtcggaaa tttagttgca attgtagtag tctttgcgat ttttgccttt
    38281 attaaaggga tatttgaact gtttgtacgg aacagattaa aagagctaac aggatataaa
    38341 ggaaagatgc ccttaataat cgggatcatc gatattctag ttggcgtctt tttcttattc
    38401 aatattggtg caggagtcgc agcattgcct tttgtttttg cagtatggtt tattgctgat
    38461 tcagttttag cgttatttac tgctgacttg gcaagaggag taagtgaagg atattattgg
    38521 tttacgatca tcgtcaatat tttaggaatt ttattaggaa ttttcttatt gtttaatcca
    38581 atttcttctg cgttgacatt aagcttttta gttggattct attttatgtt atttggtatc
    38641 acacatatcg tctatgcatt tagataagta aaatcaaaca aataaaaaag ccggcttccg
    38701 attacagttt tactgttgta attggaagcc ggctttttta tcatggacaa atatgcacga
    38761 ggtgattttt aggtgtcgag acaaatttat gcaaaaatgt gagaagctat atacacaaat
    38821 tttatcttaa tactcgaagc atagcgcagt tgtcacaacc tcttttcata taattcattc
    38881 aatactggca aatcatggac ttcatatttt tctttgaatg cttggatttc ttcttcagaa
    38941 tattttcttg gatctaaatg cagatcttct actggcaatg ggcgcttgtt attgatcttc
    39001 acatcgatta ctacaggacg atctgatttt gcagctgcat caaaggcaaa tcgaagttgc
    39061 gagtattctg tgactgtaaa gctatttgcc ccgagcgctt ctccaacttt accgaaatct
    39121 gcatcttcta aaaatacacc aaatttcttt tgttccgtat cttcttgttc tgcttcgatg
    39181 aaaccaaaag aatcattcga aaagacaaca ttaataattg gaagctgata tttgacttgt
    39241 gtaatgatat cttgcatgac catagcaaac ccgccatcac cacttaaggt aaatacttgt
    39301 ttttctgggt agcttagttg tgcggcaatt cctcctggca caccattacc catagttgcg
    39361 aaccatccag atgtcgtatg tttttgttta ccgttcatat tcaataaacg aatagaatgg
    39421 atagtcgtgt taccgacatc tgtgacgaaa atcgcatcgt cttcagcaat acgattgatt
    39481 tctttataga cagcctctgg acgaatcggt tcttcctctc gatcttcaaa agatttcaac
    39541 caatttaccc atttttcttt attttcttga tttgctaggt accagctatc agcagggcga
    39601 gcatccccta actcgacaag tctttgcaaa gctgtgtttg catcaccgag gatcgacaaa
    39661 gatgtttcat ggcgtcgtcc aaattttgac gcatcgatat cgatttggat aaattcagca
    39721 gttggattaa aaaatgcacg tccaaatggg aagtcgctac cgacaaataa gatcagatcg
    39781 gcttctgcca atgcttcatt tccgggttta gtagcgacac gtccagcaaa accaagaaag
    39841 ttttcataat catcaggaat aattcctttt gctagaacgg aagcgacaac aggaactgaa
    39901 aaatgttctg agaattcttt gatttgcgga aatccgtttc gcgttccttg accaacataa
    39961 agaactggtt tttttgcttt ttcaagataa ggcaaagcag ctagcaaatc tttttcttct
    40021 ggtaatatca cacttgtttt gtgagtgtga gcggtggaga aaggttgttc gtcaatttct
    40081 tcaaaaccaa gatcaacagg gatagtcacg atagccacgc ctttatgctc ataggcggct
    40141 ttaatggctt catctactac atgcggaaga ctttgtggtg tcatgactgt acgattgtat
    40201 acgctaacat ctgcgaaaat aggattttca tttagttcct ggaaagagtt atagttcatg
    40261 gatgtagaag caacttgtcc taagaacgct actagaggca catggtccat ctgtgcatca
    40321 tacaaaccat tgatcaaatg tgtcgcacca ggtcctgcag agccgaagac agcgccgact
    40381 ttccccgtta attttgcatc tgcagcggct gcgagtgcgc cgacttcttc atgacgaact
    40441 tgaatgtagt tgatttcggt tttttcttga tatagcgcat ccataattga attgaaagat
    40501 cctccgggaa tgccgtaaat atggtcgata ccccagcttt caagaacttt taccattgcg
    40561 attcctgcat tgatttttga catggtgttt cactccttta gcaatgatga tacataaatt
    40621 ttttgtatct agagtataga actttttatc gaaaatccca actaattcgt cttttcacaa
    40681 aaatgtagtc atgtttttgg gaatatgcta gagtagtaca tagatagatt caagagaggg
    40741 gaatggcatg gttgaatggc tattgagact tgaaccttgg cagcaagcac ttgctgggac
    40801 agcttttact tattttatga cagctcttgg tgccgggttg gtttttttct ttaaagaaat
    40861 caaaaaagaa gtgctaaact tgatgttagg atttgcttct ggtgtcatga ttgctgcaag
    40921 tttttggtct ttgttagatc cggctattac aaaagcagaa gaaaatggag atattgcttg
    40981 gctagttgta agtattgggt ttggtttagg cggtgtgttt ttatatatgg cagataaaac
    41041 actgccccat atgcattttg gaccacaaca tgaagcagaa ggattgccta cccatttaaa
    41101 acggacgatc ttgcttgttt tttctattac attgcataac attcctgaag gtttagccgt
    41161 gggggtagca ttcggtgcag cagcaactgc ggataatccg acagccgcta tattagccgc
    41221 tgtttcggtg gcgctaggta ttggtatcca aaacttccca gaaggagcag ctgtatcaat
    41281 cccgttgcga caagaaggtc tgagtcgtaa aaaggccttt gtttacggac aagcttctgg
    41341 aatcgttgaa ccaattgctg gagtgattgg agcgctacta gtaacgaaag tggagctgct
    41401 gcttccttat gcacttgctt ttgccgcagg agcaatgatt tatgtcgtgg tggaagaatt
    41461 gatccctgaa gcacagcaga cattgtccag caaacgtcat tttgcagttt ttggcgtcat
    41521 gagtggattt atcattatga tgattttgga tgtggcatta ggataaataa aaaaaatata
    41581 tatgatatat caaatagggc cgcgaactta tatcgcgacc ctattttttt agtaagttat
    41641 atcataatga agtgaatggt atcatacatt aataatagtt ttttctatgt gtatttcctt
    41701 tgatccagcg aacaagccag atgataagtg cgattgggat tagaactttg accgcaaacc
    41761 ataaaagccc gcttaggaca ctgacaaaaa gactgatgac gaagctagct gcaattagca
    41821 ctaaaagaac catgaagata tttaagaaca tatttttttg acgcatacaa aaccctcctc
    41881 ttgttcattc tttactatag aaaaagtata acagggattg tttaaaaaca cctccaactg
    41941 aagactgatt tttacttcat ctacttaaat gatcaaacaa ttgctttttc tctggtttat
    42001 catctaaaat agagcggaaa aggaggagaa tatcatgcct aaaaatcgtc ttgaagcatt
    42061 tacagatgct gtaatcgcga ttatcatgac tattttagtt ttagaacttc atgaacctaa
    42121 cggagacacg tgggaggcgc tcgctgcatt aggttaccga ttttttatct atattgtcag
    42181 ttttatcatt ttagcgattt attggaacaa tcatcatcat ttatttcaag ttgtacataa
    42241 gataaatgga cgggtcttat gggcgaacag tttctttgtt tttgcgcttt cgctttttcc
    42301 gtttgcaact tcatggatca gtgagtacat caatagcctg gctccagaaa tgacttatgg
    42361 ttttgttacc ttgaccgcta atattgcgta ttatatcttg gcaaaagaac ttgtcaaagc
    42421 aaataaaggc cacgagaaag cattgaaggc gatgttgaat aattacaaga aatcgtatct
    42481 atcgattggt ttgaatgtgt taggaattgt cttagggtat ttagtagcgc cagtagccgt
    42541 gctgatcgca aacatcgtga ttctagctgc ttggatcatc ccaagtcgta ccatcgaatc
    42601 acaatatcgg taaaatgatc cgtgtttaaa atttaagaga aaaatataga aaaaataaat
    42661 aaacgatcaa atatccgagt gatactagta ttcaaagagg gatgcagatg gatcaaaaaa
    42721 gaattcatgt aggactgatt actagttttg tcacgatgct tatttatttg gatcaaggtc
    42781 atttgacttg gacagtagtt ggtgtcgtag gatttttgac attattcaca gcaataaaaa
    42841 aataaacatc tttatgtaat ctgatgttct atctatttaa gaaaagcatg tttacagcag
    42901 tatgattctg ttgtaaacgt gtttttattt gtggaaaatt taatttttag aaaagtgtat
    42961 cgaaaaatag atagttagtt tttccacagt ggataacttc gtaagagata aaaataaaaa
    43021 attagtcaaa gaagggcgta tagatttctt ttgataggag atatacaaca gaaatgaata
    43081 aatattaacg tgttttcaaa cagtataaaa cggtgtggtt tttggaataa aaaaataaca
    43141 tatctcattt tacacttttg ttatttta
//
LOCUS       DAFKHN010000019        39576 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFKHN010000019 DAFKHN010000000
VERSION     DAFKHN010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.019"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..591
                     /locus_tag="LY912_000993"
     CDS             <1..591
                     /locus_tag="LY912_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954704.1"
                     /translation="SFFATLTILFFLCYSYLKTSHAPSSALGWLLLDHSDITEAEENP
                     FFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSFLAILFYSFNHNTLF
                     FFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSLFSFFVLALMPLTNP
                     STIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(725..850)
                     /locus_tag="LY912_000994"
     CDS             complement(725..850)
                     /locus_tag="LY912_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6954705.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYSILWEELAA"
     gene            complement(984..1880)
                     /locus_tag="LY912_000995"
     CDS             complement(984..1880)
                     /locus_tag="LY912_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBM6954706.1"
                     /translation="MNYYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKK
                     EFSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLS
                     VDEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRATAGNEKYRFITLSSIEHF
                     PLTLANYFFVQKNQLPVTKAFKELAELIGDVNEAYFFDQIEVIVDRIRKNKYKNRRPS
                     IFHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEETAFLKRQIFSELS
                     KKFIPHAFSYIKEYRTVLVSKT"
     gene            complement(2062..2988)
                     /locus_tag="LY912_000996"
     CDS             complement(2062..2988)
                     /locus_tag="LY912_000996"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBM6954707.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3073..3834)
                     /gene="pflA"
                     /locus_tag="LY912_000997"
     CDS             complement(3073..3834)
                     /gene="pflA"
                     /locus_tag="LY912_000997"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBM6954708.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGNKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4078..6309)
                     /gene="pflB"
                     /locus_tag="LY912_000998"
     CDS             complement(4078..6309)
                     /gene="pflB"
                     /locus_tag="LY912_000998"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBM6954709.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6586..9036)
                     /gene="parC"
                     /locus_tag="LY912_000999"
     CDS             complement(6586..9036)
                     /gene="parC"
                     /locus_tag="LY912_000999"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBM6954710.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     VTIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9048..11093)
                     /gene="parE"
                     /locus_tag="LY912_001000"
     CDS             complement(9048..11093)
                     /gene="parE"
                     /locus_tag="LY912_001000"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBM6954711.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLTVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEVPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11259..11693)
                     /locus_tag="LY912_001001"
     CDS             complement(11259..11693)
                     /locus_tag="LY912_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBM6954712.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEVADDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11820..12458
                     /gene="plsY"
                     /locus_tag="LY912_001002"
     CDS             11820..12458
                     /gene="plsY"
                     /locus_tag="LY912_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBM6954713.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12590..13465)
                     /locus_tag="LY912_001003"
     CDS             complement(12590..13465)
                     /locus_tag="LY912_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBM6954714.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNREIFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADAVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13547..14338)
                     /gene="codY"
                     /locus_tag="LY912_001004"
     CDS             complement(13547..14338)
                     /gene="codY"
                     /locus_tag="LY912_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBM6954715.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14356..15756)
                     /gene="hslU"
                     /locus_tag="LY912_001005"
     CDS             complement(14356..15756)
                     /gene="hslU"
                     /locus_tag="LY912_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBM6954716.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALIKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15770..16318)
                     /gene="hslV"
                     /locus_tag="LY912_001006"
     CDS             complement(15770..16318)
                     /gene="hslV"
                     /locus_tag="LY912_001006"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBM6954717.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16355..17260)
                     /gene="xerC"
                     /locus_tag="LY912_001007"
     CDS             complement(16355..17260)
                     /gene="xerC"
                     /locus_tag="LY912_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBM6954718.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17458..18834)
                     /gene="trmFO"
                     /locus_tag="LY912_001008"
     CDS             complement(17458..18834)
                     /gene="trmFO"
                     /locus_tag="LY912_001008"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBM6954719.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLDSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18803..20881)
                     /gene="topA"
                     /locus_tag="LY912_001009"
     CDS             complement(18803..20881)
                     /gene="topA"
                     /locus_tag="LY912_001009"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBM6954720.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDIVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21003..21860)
                     /gene="dprA"
                     /locus_tag="LY912_001010"
     CDS             complement(21003..21860)
                     /gene="dprA"
                     /locus_tag="LY912_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBM6954721.1"
                     /translation="MYQIEENLLKLAYAKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITTHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVVEAGYVIVSGCAKGIDTYGQQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHRFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21916..22683)
                     /locus_tag="LY912_001011"
     CDS             complement(21916..22683)
                     /locus_tag="LY912_001011"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBM6954722.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22676..23536)
                     /gene="ylqF"
                     /locus_tag="LY912_001012"
     CDS             complement(22676..23536)
                     /gene="ylqF"
                     /locus_tag="LY912_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBM6954723.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23797..24195
                     /locus_tag="LY912_001013"
     CDS             23797..24195
                     /locus_tag="LY912_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBM6954724.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWVMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24474..24974
                     /locus_tag="LY912_001014"
     CDS             24474..24974
                     /locus_tag="LY912_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBM6954725.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRVIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(25057..25608)
                     /gene="lepB"
                     /locus_tag="LY912_001015"
     CDS             complement(25057..25608)
                     /gene="lepB"
                     /locus_tag="LY912_001015"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBM6954726.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25760..25987)
                     /locus_tag="LY912_001016"
     CDS             complement(25760..25987)
                     /locus_tag="LY912_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBM6954727.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(25984..26502)
                     /gene="msrA"
                     /locus_tag="LY912_001017"
     CDS             complement(25984..26502)
                     /gene="msrA"
                     /locus_tag="LY912_001017"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBM6954728.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(26522..27235)
                     /locus_tag="LY912_001018"
     CDS             complement(26522..27235)
                     /locus_tag="LY912_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBM6954729.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27238..28134)
                     /locus_tag="LY912_001019"
     CDS             complement(27238..28134)
                     /locus_tag="LY912_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBM6954730.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28292..29134)
                     /locus_tag="LY912_001020"
     CDS             complement(28292..29134)
                     /locus_tag="LY912_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBM6954731.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEEILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29266..29919
                     /locus_tag="LY912_001021"
     CDS             29266..29919
                     /locus_tag="LY912_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBM6954732.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(29983..30510)
                     /locus_tag="LY912_001022"
     CDS             complement(29983..30510)
                     /locus_tag="LY912_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBM6954733.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEIDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(30530..31477)
                     /locus_tag="LY912_001023"
     CDS             complement(30530..31477)
                     /locus_tag="LY912_001023"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBM6954734.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKEVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(31489..33375)
                     /locus_tag="LY912_001024"
     CDS             complement(31489..33375)
                     /locus_tag="LY912_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBM6954735.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSGDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(33540..35612)
                     /locus_tag="LY912_001025"
     CDS             complement(33540..35612)
                     /locus_tag="LY912_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBM6954736.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRHADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKRVQ"
     gene            complement(35625..35900)
                     /locus_tag="LY912_001026"
     CDS             complement(35625..35900)
                     /locus_tag="LY912_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954737.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(36262..36717)
                     /locus_tag="LY912_001027"
     CDS             complement(36262..36717)
                     /locus_tag="LY912_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954738.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(36871..38079)
                     /locus_tag="LY912_001028"
     CDS             complement(36871..38079)
                     /locus_tag="LY912_001028"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBM6954739.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPSLKEEGEALLRFAELPSVPLKEESQVWTLLISQLGLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(38191..38523)
                     /locus_tag="LY912_001029"
     CDS             complement(38191..38523)
                     /locus_tag="LY912_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBM6954740.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            38671..39546
                     /locus_tag="LY912_001030"
     CDS             38671..39546
                     /locus_tag="LY912_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBM6954741.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
BASE COUNT        10612 a         8318 c         6809 g        13837 t
ORIGIN      
        1 tctttttttg caactttgac gatcttattt tttctatgtt attcatacct taagacctca
       61 catgcgcctt ctagtgcatt aggctggttg cttttggatc attctgatat cacagaagcc
      121 gaagaaaatc cgtttttttt gattttgtct tctctttgcg gcttactgtt ttctgtttat
      181 ttcggtgcct atttttttca tcgacatcct ggtacgttaa acgaagcttc aagcgtattg
      241 attgcattta aaacgttttc ttttttagca attctttttt attcgtttaa tcacaatacg
      301 cttttcttct ttatcatgaa tggtttagtc gtgattttat ccatttttac ttattttatt
      361 ttttcactca tttttagcca attgaaatgt ccactcttct ttcgattagt tcctgtcacc
      421 tgttttattt acagcttgtt ttcctttttt gtccttgctt taatgccact gaccaaccct
      481 tcgacgatcc aagtcgcagg aaatctgttg gatatgctct tcatcgtcag tctaggtgta
      541 tttatgtggc aaagaaaaaa caaacaaaat aaaaagcatt ttgaagcctg actattacga
      601 cttcataaat gcttttttag ttttaaacac ttcaatctaa aagaataacc caagattgga
      661 taaattatta atgactcgcc attcgtttct tagtgattct ggatcatcaa atggacttcc
      721 taatctaagc agctagttct tcccataaaa tgctatactt gactgaatca taatattgat
      781 tatttaaaaa tctaactttt cttatcacta cttcctttgt cattccacat ttctcaccat
      841 ttttttgcat tcctttgttt ccagaccatg tagtgaatcc aataggtggt agataggcaa
      901 aatactcaaa taattctttt aaccataaag gaagagaaag gctcctcctg caagagtcag
      961 tataattttt gcttactgct ctcttaggtt ttactcacta aaactgttct atattctttg
     1021 atataagaaa atgcatgcgg tataaatttc ttgctcagct cagaaaagat ttgtcgttta
     1081 agaaaggccg tttcctccat tgtcaatgaa ggatccaatg ttggtaattc aatctcaaaa
     1141 ttgttttttt cgacaatagg taattctaat gtgaatgatt cttcttcctt tatagtattc
     1201 gtcacaagta gagactgatg gaaaatacta ggccggcgat ttttatattt attcttacgt
     1261 atcctgtcaa cgataacttc tatttgatca aaaaagtacg cttcatttac gtctccaata
     1321 agttcggcta attctttgaa tgccttcgtt acaggaagct gattcttctg tacaaaaaag
     1381 taattagcca aagtaagcgg gaagtgttct atagaggaaa gtgtgataaa acggtacttc
     1441 tcatttcctg cagttgccct cagcaattct gtctctcggc tgtttcttac tccataaaaa
     1501 tacgcttctt tccgttcatc ttcgaaacaa tacgcccaaa taacttctcc catcgctaat
     1561 ttttgttcat caacagagag tctcttcaat tgttcagcta tggtttcagc agccgaagtg
     1621 gcttgttgca agtaatcttt aggatcaaat attggaaagt tcaaatgata tcttcgttct
     1681 tccctcttga ttaatcctgc atcgatcaat agatcaagaa aatgggaaaa tttattttgc
     1741 gaaaattctt ttttcaattc tcttagaatc gtttcttgtt ctcgatgttc atatagataa
     1801 tcggtcaatg aagaaaaaag cggatcatcg gtcagttttt gataaaagtt ttccttattt
     1861 tttgaataat aatagttcat atatgttctc ttttctatcc gttttatttt acttaaaagg
     1921 cttttacgta aaaaggagga agaacaagag tcataattga ctgttattct cctccatttc
     1981 ttcggccttt agtatgttct atgtttcttt ttatatcaat cgcttatcca ttcattttga
     2041 atgcttcata ctaccctttg attagctaaa tacagccgtc aattgaggta cgacttgttt
     2101 tttacgtgaa acgacacctt taagcaaagc acggttgttg gtcaaagttg tttggaaagc
     2161 ttcttctact ttttcttttc ctttaccagc aacaagtaat tctgaatcac tgtctaagat
     2221 gtttgtgaca actaatacga acagatcgta gccatttgct ttcatttcat cttccattgc
     2281 tgcttctagc tctgcttgtc gatccatcac ttcattaaga tccactgtat tgacttgagc
     2341 gatacgaacg ttggaactgc ccattgggaa actttttgca tccaaatcaa gaagaaccgc
     2401 agctgattta tcacttagat ttgttcctgc tttcaacatt tcaagtccat aagtgtttag
     2461 atcgacttca gcgattgctg caagttcttt tgcagctgct tcatcttcag gcgtacatgt
     2521 tggtgatttg aacaacaatg tatctgaaat gatagctgag agcatgattc ctgcgatttc
     2581 tttaggaatt gttacttggt tttctttata tagttttaaa ataatcgtac ttgtacatcc
     2641 aactggttct gcacgatagt acaatggatt agctgtttca aagtttgcaa tacgatggtg
     2701 gtctactaca gctaaaatat ttacttcgct gatatctgaa atactttgtt ggaattcatt
     2761 atgatccaca agcatgacat ctgcattttc tgctttagct gactctacta ctcgtggtgc
     2821 agatagctga aagtggtcta atgcgtattg tgtttcttca ttaggtgtac ctagagcaac
     2881 tgcttctgtt tctttaccta attcattttg caagtgtgaa aacgcaatgg ctgccccgat
     2941 tgcatctgta tctggatttt ggtgaccaaa aactaaaatt tttgacatgt cattcgctcc
     3001 tttgtgattt ctcctattta ataatagcaa aaaaacggaa agaagcaata cttatcttct
     3061 ttccgatgcg acctatcgcg ttaaatattt tgtatactct tctgtatgaa gcaatcgttt
     3121 agcattttcg acacgttctt ttgtaggtgg ttcgatccct tctaatggat atttcaaacc
     3181 aagtgtttcc cacttgtatt ttcccatcgt atgataagga agaatctcta ctctgtctac
     3241 atttgacaag gtttgaataa agttgtctag tcggatcaaa tattcatcat aatcacttcg
     3301 ctcaggaact agtacatggc gaatccaaac cggtttgttg atttttgaca aatattgagc
     3361 catttctaaa atattttcat tgtcccaatg cgttagtttt ttatgctctt cattatcgat
     3421 gtgtttgatg tcaaataaca gtaaatctgt atacttcatc aattcttgaa aacgtgaaaa
     3481 gaaaggttct tcatacgtaa aaggttttcc gcatgtatcc aatgtagtat gcatcttccg
     3541 ctcttttgct tttttaaata gttcgatcaa aaaatcgatc tgcaatagag gttctccacc
     3601 actaacagta ataccacctt tatttcccca gtaaggtctg aagcgttctg ctttatctaa
     3661 aagttcatct gctgtgtatt ctttccctcc gccaatattc caagtatctg gattgtgaca
     3721 aaattggcaa cgcatgcggc atccttgcat aaacacgaca aagcgcagtc caggtccgtc
     3781 tactgaaccg aaagtttcga tagaatgaac atagccgatt gttttttctt ccatttaagt
     3841 tcacatcttt tctttgattt cattttaagt acaagttagc tgtcgaagcg aagctttctg
     3901 aacaaaattt ttcgcaattg ccgcttcgtt atgtgtaaaa tttacaggga cggaacatac
     3961 aagtcctgcc cctgtaaatc gtttctttca aataagcata ctgattattc gattttgatg
     4021 cgatggctat tcaacgtcct ttcgacgcta agtcgaaaaa cttttttcac gaacttttta
     4081 cattctgtcg tgtgaagttc tcatcaagac atctaattgt tgttctcttg tcaagtcacg
     4141 gaatttaact gcataaccag atacccggat cgtcaagttc ggatatttca ttggattttc
     4201 cattgcatca cgcaataaat cattactgaa tacattgaca ttcaaatgat aagctccttt
     4261 tgagaagtat ccatctaaga cattacgcaa gttttcgatt cttgtatctt gttcttttcc
     4321 aagacctgaa ggattgattg tttgggtatt tgaaattcca tccaatgcac agccgtaatt
     4381 cattttagct gttgagttca ggctagctaa taacccactt tgttccgcat tgtaacttgg
     4441 atttgctcct ggcgcaagtg gttttccagc ttcacggcca tcaggagtat ttcctgtatt
     4501 tttaccgtaa acaacatttg aagtaatcgt caataatgaa gttgttggtt ttgagttgcg
     4561 gtaagtttta tgacgtttga tttgtcccat gaagtattcc aagatccatg aaactaattc
     4621 atctgcacgg tcatcatcat ttccgtattt agggaagtcg ccatccactt caaaatcaac
     4681 tgctattcct ttttcattac ggattgcttt tacttttgca tatttgatcg ctgacaagct
     4741 gtctgccgca tgagaaatcc cagcaatacc tgtagcaaat gtgcgttgca agtcagaatc
     4801 catcaaagcc agctgagctg cttcataaga atatttatca tgcatataat gaatgatgtt
     4861 caacgtattg acatatagtt ctgctaacca atccatcata ttcatgaagt tatgtttcac
     4921 ttcttcaaag tctagtattt ctgatgtgat tggacgatat tctggtccaa cttgggcgcc
     4981 agtcacttca tcgactccgc cattgatggc atataatagt gttttagcca agttagcacg
     5041 agcaccaaag aattgcatgt cttttccgac aactgttcct gatacacagc aagcaatcgc
     5101 acaatcatca gaaccccatt gttcacgaag ctgattatca ttttcgaatt gaatcgaaga
     5161 actttcgata gcgattctgc tagcatatgt tctgaatcct tctggaaggt gttcagaata
     5221 caaaacagtc aagtttggtt ctggtgaagg tcccatattt gttaatgtat gaagcagacg
     5281 gaaatcattc tttgtaacta atgaacgacc atctaatccc atacctgcaa tggataaagt
     5341 agcccagata gggaatcctg agaataattg gttatattca ggtgtacgcg cgaatttgac
     5401 catacgtaat ttcattacta agtggtcgat caattcttgt gcttcttttt ctgtgattac
     5461 tccattatcc aaatcacgtt ggatatagat atcaaggaat gctgagatac gtccgattga
     5521 catcgcagca ccattttgtg atttgattgc tgctaaatat ccgaagtata gccattggac
     5581 agcttctttt gcatttgcag ctggtttaga aatatcatag ccatatttcg cagccatttc
     5641 tttcatttgc gctaatgcac gatattgttc agtgatttct tcacgtaaac gaatcacttc
     5701 ttcactcatt gtatgataac cagtcatatc atgatctttt ttcttttgtt ccatcaaata
     5761 gtcgattcca tacaatgcca cacgacgata gtcaccgatg atacgtccgc gaccgtaagc
     5821 gtctggaagc cctgtaatga ttttgttttt acgagcagca cgcatttcag cagtataagc
     5881 gtcaaataca ccttgattat gtgttttgcg ccagtcagtg aaaatatgtg tcaattcatc
     5941 gtttggtgta tagccattac tttttagcgc attgttagcc atattgattc cgccgaacgg
     6001 catgaatgct tgtttcaaag gtttgtctgt ctgtagaccg acgatttttt ccaaatcttt
     6061 atccaaatag cctgcatcgt gtgaagtaat agttgatacg atttctgtgt ccatatcata
     6121 gacaccgtta cgctcgaatt ggatatcatt taacttttgc aattcatccc ataatttttc
     6181 tgttgcttct gttgggcctt ccaaaaagct gtcatcaccg cgatattcag tgtagttatt
     6241 ttgaataaag tctctagtgt ctacgccttc tttccatttg gtacctttaa atccattcca
     6301 ttgctccatt gtatggacct cctaaatttc tgttttatgt aacagttttt acgtgattag
     6361 tataacacag gaccctatct ttgcaagggt tttcttgttt tttatttaac aatttttatg
     6421 ttttatttac atatatttaa atcaacgttg acataccaac atttaagcat tgtgaacact
     6481 ttcatctttt tttgcaaacg tataaggatt tattaaaaat gaatgaaaaa gagacgccgc
     6541 ctgtattaat acagatggcg tctcttcatt aaaatactac aacagttacg actcgatgaa
     6601 aatctcagga gcatcgataa cttcgatgac ttctccacct tttttctcat ccatcgcaaa
     6661 tgatccattc gatgttcgat cacctatagg gaaatcagtt gggtcaatcg ttaactgctg
     6721 ccctttttga ttcatcaagg ttatttcttt tgatcttcct tccgacatat agataatacg
     6781 gtgcggattt tttttcagct cacgcatgac cgtcactccc cgcttcgcac gtgaagtttg
     6841 gctgatttct tgagcaagca tgcgtttaac agctcctcgc tgagtaacga ttacgatcgg
     6901 cgtatcacct tctgctaaca caagcagccc gttgataatc ctatctccat ctttcaaatt
     6961 catagacttc actccagctg cctttgctcc aacaacggga acatctgtta aaggatagcg
     7021 caaacccatt ccttgatgcg ttactaagaa aacatctaag cctggctgat cttctttcag
     7081 atacacagca atcagttcat cttcttccgc ctttagcttc atacagctga gcggacggct
     7141 cttataggtg cgccatggtt cgaactctgt cattcgtgtt tgcttgatca atccattctt
     7201 gctgatgaat acaaatgttt tctctgcttg aattttttga tatgggaaaa cagctaaaat
     7261 cgattcgtct acagacagat tggagattgt ttgagaaatg tgctcaccag catctttcca
     7321 tttcaaatcg ggtagttcat ggacagggcg gtagatcaca tttgctttat ttgtgatcag
     7381 aagaacatgg tccaatgtac tcaattcacc tgagtatagc aagtagtcgc cttctcgcat
     7441 cccgatttct tctggtttgg aagcactata agaacgaagg cttgttcgct tcacatagcc
     7501 ttctcgcgtc acactgacaa ttacgtcttc ttgtgccact aagacttgcg tatcaatttt
     7561 gatttcttcg atttcgtctt cgattgtcgt tagacgagcg gaagaataat tttttttcac
     7621 ttctcgcaat tcttttttca taacagagaa aagctctttg tcatttgaaa ggattttatt
     7681 caactctgtg atttgcgcaa tcaagctttc ggattccttt tgaagctctg tgatatccgt
     7741 gttcgtcaaa cggtataatt gcaatgtgac aattgcttct gcttgttctt ctgtaaattg
     7801 aaagacgtcg actaaattct ttttggcgtc ttttttgtct ttactttcac gaatcgttac
     7861 gattacttca tccagaatcg ataaagcttt catcaatcct tctacgatat gctgtctttt
     7921 ttgagctttg gctaaatcga attgactacg ttttgttatg acttgctttc gatgctcgat
     7981 ataacttctt aaaatgtctt tcagtccaac ttgatgcgga gtcatatggt cgatagcgac
     8041 catattgaaa ttgtaattga tctgtagctc agtgtttttg aacaaataat tcaaaattcc
     8101 ttgagcattg gcgtcttttt tcaattcgac gacaatttgc agacctgttc tatcactttc
     8161 atctcgtact tcagctattc catcgatttt cttattcaaa cggatctcat ccattttttt
     8221 caccaaggtc gctttattta cttcatatgg gatttctgtg atcacgattt gctgtttatt
     8281 acccttcatt gcctctatct ttgttttcga acgaagaata acttttcctc gccctgtttc
     8341 ataagctttt ttgatttcat cttttccttg caagatccct cctgttggaa agtcaggtcc
     8401 aggaatatat tccatcaatt tttcaaggct cgcttgtgga tgatcgatca tatagattgt
     8461 gccatcaatc acttcagcta agttatgagt cgggatttct gttgcatatc cagcagatat
     8521 acctgtcgat ccattgacga gaaggtttgg gtatcgagct ggaaggactg ttggttcttt
     8581 ttctgtatca tcaaaattcc acacgagatc gactgtttct ttttcgatat ctgctagcat
     8641 ctctccactt aacttggata atctggcttc agtataacgc atcgcagcag gtggatcacc
     8701 gtccatactc ccgttattcc cgtgcatttc gatcagtact tcccgcaact tccagtcttg
     8761 gctcatgcgg accatcgctt cataaatact gatgtcacca tgaggatgat aattccccat
     8821 gatatttccg acagattttg ctgatttacg gaatcctttg tcatacgtat tgccatcttt
     8881 gttcatggca aataatatcc ggcgttgcac tggcttcaat ccatcacgga tatcaggcag
     8941 tgcacgttct tggataatat atttggaata acgtccgaag cggtcaccca tcacttcttc
     9001 taaagttaat tcttgtactt cttgtcgatt ttccatcagg tgacctccta ttctacttca
     9061 aataactgat tgttttcatt tttatctgct cgttcttcat ctaataaatc attagaaact
     9121 gaaggagaga tttcagtatc ctctttttta tctaagatac tgccatcttc ttcgagcgta
     9181 aattgcacgt gattttcgat ccattttctt cgaggttcta ctttgtcacc catcagtgtg
     9241 gttactcgac gttcagcttg cgcagcatca tcgatacgga cgcggatcaa cgtacgggaa
     9301 gtcggatcca tcgttgtttc ccacaattgt tccgcattca tctctccaag tcctttatat
     9361 cgctgcagca tatatccttt gccgactttt ttaatcattg ctgccaattc gtcatctgtc
     9421 cacgcatatt caatgacttg cttctttcct tgtcctttgg atactttata taaaggcggt
     9481 aacgcgatat atactttccc agcttcaatc agcggtttca tataacgata aaagaaagta
     9541 agcagtaata cttgaatatg ggcgccgtct gtatccgcat cggtcatgat gattactttg
     9601 tcgtaattac agtcttcgat agaaaactca ggaccgactc ctgcaccaat cgtatagatc
     9661 atcgtattga tttcttcatt tttcaagata tcttgcattt tagctttttc ggtattgatg
     9721 acttttcctc gtaaaggtag aattgcttgg aactttctgt ctcttccttg tttagcagat
     9781 ccgccagcag aatccccttc gactaaatac aattcatttt tcttagggtt tcgggattgt
     9841 gcgggtgtca attttcctga aagaagagat tcgccttttt tacgcttctt cccatttcgg
     9901 ctttcttctc tggctttacg tgctgcttct ctcgcttctc tggctttgat tgctttacgg
     9961 accaacatct ggctcatttc gctattttcc tgcaaataaa agcccatttg ttcactgatg
    10021 acgttatcta ctacggtacg agcaactggc gtaccaagtt tttcttttgt ttgcccttca
    10081 aattgcagaa gattttcagg tacacggata gaaagtacag cagctaaccc ttctctgaaa
    10141 tcactacctt ccagattctt gtcccgttct ttcagcaaac caacttttct cgcatattca
    10201 ttataagatt tcgtcattgc cgctttcatt ccagcttcat gggttccccc atcttttgtc
    10261 cgaacgttat tgacaaaaga taagacattt tctgaatacc cgtcattgta ttgataagcg
    10321 acctctactt cgataccttc tttttctccc gaaaaataaa caactggtgt caatgtatct
    10381 ttttcttcat tcagataatc aacaaattct ttgattcctt cttcgtaatg aaaaatttcc
    10441 ttgactggta cttctccacg aagatcagaa agagagattt taacgccttt tagaagaaag
    10501 gcagattctc ttaaccgttc ggctaaaatt tcatatgaaa atttcgttgt actgaatatt
    10561 gtatcgtctg gtaaaaaatg gacagtcgtc ccgtttgctt tttttgtttt tcctatcttt
    10621 ttcaacgtac cgtcaggttt accgccgttt ttaaatttct gctgatactc tacgccatct
    10681 ctaacgatcg ttacagttag ccatttcgat aaggcattta ccacactggc tcctacaccg
    10741 tgcagtccac cagaagtttt gtaccctcct tgaccaaact ttccgccagc atgcagcaca
    10801 gtaaaaatca cttcaactgt tggtattccg gaagcatgca ttcctacagg catcccacgt
    10861 ccgctatctg caacagttat actattgtct tcatggatgg tcacatcaat ctcactgcca
    10921 taacctgata atgcttcgtc aactgcatta tcgacgattt catagactaa atgatgcaag
    10981 cctcggctgt cagtggatcc aatgtacatc cctggtcttt ttctaactgc ctctaatcct
    11041 tccaatactt ggatggacga gtcattgtat tcgttgttta ctttttttgc caaggcaaac
    11101 gctccttcaa taatactttg cggcaaaacc gcaccacgat tatcatacta gaaaaggtcg
    11161 tgaaaaaaaa gagggtagac gagaaatcaa ttttaattat ctcctaaccg ctttttcgac
    11221 attcccctct atcgatcatc tcttctttgt ggtcattttt atttttggtt ttctttcaac
    11281 ttaccaagtt caatcttaat acaacgatcc atcacgatat ctgtacgtcc tgcttttctt
    11341 agcatctcag ctgcttcttt gttttcaatc cctaattgtg cccagaacac tttagcatca
    11401 gttttcaaaa aatcatctgc tacttcaggt aaaaattcac tccgtctaaa tacatctacg
    11461 atatcgattg gatcatcgat ttctgtcaaa ttcgcataga ctttctcgcc tagaatttct
    11521 tcaccagcca ataatggatt tactggtatg attttatatc cattgtcttg caatacctgt
    11581 gcaaccatgt aacttgttcg ttctggttta ttgctcaagc ctacgacggc aatatttttt
    11641 gcttcttcca aatagttgaa aatcgtttct tgtgttggat tttttacaga catttctgcc
    11701 accccttgct tttcttttta ttccatctat tatacttgta tctttcattt tttcaattgt
    11761 tcctgttacc tattcatgct aaaataaagg atagttttca acttgaaaga gggtaaaaaa
    11821 tgaaattgat cttattactt attttagcat atcttttagg ttctattcct tccggtgtct
    11881 ggattggcaa attgtttttc aaaaaagata tccgacaaca cgggagcggt aatactggaa
    11941 cgaccaatac atttcgtgta ttaggcaaaa cagccgggat tgttgtcctg cttatggata
    12001 ttttaaaagg tacattggct acttgtttgc cgatgatctt ccacctttct gggattaacc
    12061 ctctttggtt tggggtatgc gccattcttg gccatacatt tccgattttt gctgggttca
    12121 aaggaggaaa agctgttgcg acaagtgcag gaatgctttt aggatttaat cctgtatttt
    12181 ttgtttattc ttgtatcatc tttatcgtta gtttattttg tacaagtatg gtgagtttga
    12241 gcagtatgat cagtgcagta ttgatcactt tatctacgat cgtccttcct tatgtagctc
    12301 ctgtgatttt ggctaagccc aattggttac tgacgatcat tgccttttta gtttcttcct
    12361 ttatctttta tcggcataaa gacaatatca agcgtatcag aaaccatact gaaagtcgaa
    12421 tcccgtttgg tttgaatagc agcaagaaaa aatcctgata ctttttcatt ccaaagagat
    12481 aaaacgggag tgtgacaaat cgatgtcaca ctcccttatt acttacagga tagctttttt
    12541 acacaccttg gtaaacggtg ttccctgcta acttctcggt cacaacctct tacttcactg
    12601 tgatggaata ttttgtcttg aagatttcat gggcacctag ttgattgatc cctacttttt
    12661 ccatcaagtt tccactactg ttcaccgcgt cagcgattcc gcaccacggt tcgatacaaa
    12721 cgaaaggcgc ttcttttgga taaggagacc agatccctac ataaggcata tctttatagc
    12781 ttaaagttac gctatgggaa gatttttcac ttcgaatggc atacgcattt agaccccttg
    12841 tttcaaaaac caaggcatct tgctcaaaaa tttcacgatt caaagccaga ttcgtatttg
    12901 tctgacctaa cgtcttttga tccatatcga tgaatgggcc tttcaatggt aggcgtaatc
    12961 ttgatttcaa tggagaaaat gccagataga aatcttcaaa tgacaatcct tcttcaagag
    13021 gtacattgaa agcaggatgt ccaccgatag aaaagaacat ttctttttca ccggtatttg
    13081 ccacttgata atgaaccgtg atgccgtctc ctcctaattc atagctgatc actaattcaa
    13141 aatcaaatgg atacttttct aatgtctccg gcgtactcct taagatgaaa ctagccattt
    13201 cttgtccatg ttcaatgact tcaaaatcca tatcccgagc aaatccgtgt tgccccattt
    13261 gatatgtttt cccttgataa acatactgat catcttttaa acgtccaaca aaagggaata
    13321 aaaccggtgc atgtctgccc caatacgctg gatcaccttg ccagatatac tctaaaccat
    13381 gttcttttga tttcagactg atcaattccg caccgtgttc agcgatttcg gcgatcagct
    13441 ggtcattttg aataataaca gtcattgcca ttcctccaac ttcgacttac tttttaaaat
    13501 gggaaggctg gaacaaacat ttctatctgc cccagtcccc ttacttctaa taactgtgtt
    13561 ttgctaactc gtctttaaaa cgggaattca atacttttaa ataagttccc ttcatgccta
    13621 acgaacgaga ttcaatgatt ccagctgatt ccaattttcg taaagcattg acgatcacag
    13681 aacgagtgat gccgatacta tcggcaatat tagaagcagt cagacgacct tcatctccat
    13741 ccaatgcttc aaagatagct tgtacagcct tcaattcgct ataagataat gtgttgattg
    13801 ccatttggac agccgttgca ctccgtacat ctgcttcgat gcttcgagac ttctgataaa
    13861 ggatctgcat accgacaacc gtagctccat attctgctaa gactagatcg tcatctgcaa
    13921 acgattgttc catacgagat aagataatcg tacccaaacg ttcgccagct ccaaagatcg
    13981 gaacgacagt cgtcagacca aatggatatt tctctcttga ctctaccgga aatgcagtaa
    14041 tatcactagt aattgggata ttagcttcag ttttcatcaa ctgtgccact gtatcagtat
    14101 aagattcagg aaattgtttc tcaacaaaca ttgttttgat tcgttcattg ttcacatcgt
    14161 gacgttcatt ataacctagt aatactccgt cacttcctat gatataggtg ttgctgtcaa
    14221 gaataccacc tagtgtgaca gccattttat cgtaaggcaa atctgcttgc atgtcaaaag
    14281 tattcttttg ctgcaaaagt gtgtttatct tgcgggtttt cgttagcaag tctgtcattg
    14341 tcgtcctccg attttttata aaatatagcg acttaaatct tcatttgccg caattgagcc
    14401 aagtttgtca tccacatatg cttctgtgat cgttatttct cccatttgca tatctggtgc
    14461 ttcaaataat agatcttcta gtagtttttc caaaatggta tgcagtctgc gtgcgccgat
    14521 attatctgtg tcacggttga catcgaaagc gatttgagcg atccgttcaa ttgcttcttt
    14581 tgtaaacgta actgacacat tttctgtacc aatcaatgct acatattgtt ttattaaagc
    14641 attattcggt tcagtcagaa ttttcacaaa atcttcagct gtcaaatcat ctaattctac
    14701 ccgtattggg aaacgccctt ggagttctgg aatcaaatca ctcggtttag ataaatggaa
    14761 cgctcctgaa gcaatgaata agacatgatc tgtttggatg atcccgtatt ttgtatttac
    14821 ttgtgaacct tcgacgattg gcaatatgtc tctttggacg ccttctctgg atacttctcc
    14881 agattgctgt gatttagaag tgatcttatc gatttcatcg ataaaaataa ttccactttc
    14941 ttccgctaat ttgattgcct cactatggat atcagcatcc ttgactaatt ttgctgattc
    15001 ttccttgatc aataactcta aagcttcttt gactgttacc gtccgttcca cttttttctt
    15061 cggtgtcaaa gcacctagag tttcatttag gtcgatcccc atttgctcca atccattgtt
    15121 catcattggt gcaggtttct tttggtcttc aacttcaatg gttacttcac gactatccag
    15181 taaacccttt tgtagttgtt ccaagactgt acggcgattg attcgaatat cttctgtcac
    15241 ttcttcttgc ggttcagcgg tattttgctg actagcatta aaaagattca tcatttgttc
    15301 aaattgatta gtggattgtt tctgttcttt tttgatacca ggtaccaaga tttttaccaa
    15361 acgtttttct gcattttttt tagcacttgt gtatacacgg ctgtactgct ctttttctac
    15421 gatttggatc gcattttcta ctaaatcccg aaccattgat tctacatctc ttccgacata
    15481 accgacttca gtaaattttg ttgcttcgac tttgacaaat ggtgcattga cgatttttgc
    15541 caaacgtcgt gcgatttctg ttttaccgac ccctgtaggt ccgatcatca gcatattttt
    15601 tggtgtaata tcttgttgca ttttttcatc taactgcaaa cggcgatagc ggttacgcaa
    15661 agcaacggca acagattttt ttgctgcgtg ctgtcctacg atatattcat ctaattcact
    15721 tacgatttgt cttggtgttt gttttaattc atacatatct actcacctct tacagttctt
    15781 ctacgataat attatgatta gtaaagatac agatatctgc ggcaatattt aacgcatttt
    15841 ctgcaatttc tttcgcactc atgtcgtttt gagcatagtt tttcattgct cgggctgcag
    15901 ccaacgcaaa attccctcct gatccgatag ctaagatacc atcatctggt gtgataactt
    15961 ctcctgtacc tgaaacaaga agcatttctt tatcattcat tacgatcagc atcgcttcaa
    16021 gtttttgcat agattgctgt gtccgccatt cttgagctaa ttcgacagct gcgcgttgta
    16081 gattcccgtt atattcgttt agtttgcctt caaatttttc ttctaaagta aacgcatctg
    16141 caacacttcc ggcgaaacct acaacaactt ctccattgta gatacgtcgt actttctttg
    16201 cagtgccttt catgacaaca gattcaccca ttgttacttg gccatctcca gccatagcaa
    16261 atttcccgtc tttttcgacg gcacagatag tggttgaatg aaatggtgat tcgaccatgt
    16321 ttgtttcctc ctaaatttgt tcttttcctt atttttacgc tcttggatgg aaagaacgat
    16381 agtttttttg taaactttct tttgttacat gggcatagat ctgggtagtc gataaattgg
    16441 catgtcctag caattcttgg actgtccgca aatctgcccc attatttaat aaatgagtag
    16501 caaatgtatg gcgcagcatg tgaggatgga tatcactatc caaactgctt tttttgatca
    16561 tttgattcaa gacatattca attccagtag gcgtgattgg ttttccatga tgattcacaa
    16621 aaacgatatc atgctcttcg tgatattttg tcatcaatac ctggcggcct tccctgaaat
    16681 attcttgcag agcatcttga gcaaaagaac ctagaggagc atatctctct ttgttccctt
    16741 taccatggat caacatgacc tctgaatcaa aatcaatgtc tgataccgac aaactgctac
    16801 actcacttaa acggatgcct gacccgtaaa ggacttccag taaagcgcgg ttcctcaaat
    16861 ccaaaggact atctcctgct acgctgtcaa aaagtgcttg catttcattt tcataaaaaa
    16921 aacgtggcag tctcaaattt ttctttttga gatgaacgta agaaaatgga ttttctttta
    16981 tcacttcttc tttgagaaga tactgataaa acgaacgtag gctggctatc ttgcgactga
    17041 tagaatttct gctatagcta ggacgatgat cagctaatgc actcaaatag acacgaaccg
    17101 taaaatattc cgccttcagc agatcagcgt ctccagattc ctccaaaaaa tgtttgaaat
    17161 ggagaatgtc ttcttcatat gcttctttcg ttttttctga atatcctctt tcgacaatca
    17221 aataacgcaa aaatttttgt tcccacgtgg cttctgtcat tttctcacct tccttttgtc
    17281 ccagagaata atttagcaca gcgtttataa aaagacaaat aaattgtcag aatttaacca
    17341 atatttctaa gtttgttcac aattggcgca attcctcaca ttttgtttga gaaattctta
    17401 agaaaaacgc aagaaaaaga gcgagactat ccgtctcacc ctcttcatgg agtttcctta
    17461 ctcatttggg attgcagttt tttctaattc tgtttttatt gcctcattag cttttaaagc
    17521 tcgttgtgca attgcttcat atcttgcttt tttgtctcga atgcgctctg gcagttcagg
    17581 aaacagacca tagttggcat tcatcggttg gaaatgtttt ccttccgcat gagtaatgta
    17641 gtatgccata cttccaatag ctgtttcttg tggaaactcg actggttcca tttcttttgc
    17701 taagcgtgcg gcgttgattc cagcaagtag tccgctcgct gcactttcaa catagccttc
    17761 tacaccagtc atctgacctg caaagaacag atcttcgcgt ttcgttgatt ggtaagtcgg
    17821 tttcagcaat tctggcgaat tcataaagct gtttcggtgc atcacaccat agcgaacgaa
    17881 ttcagcattt tctaacccag gaatcatccg gaaaacacgt ttttgctcgc cccatttcaa
    17941 gtgagtctga aagcccacga tgttgtataa agaagctgca gcattgtctt gacgcagctg
    18001 gataacagca taaggacgtt tgccagtttt aggatcttcc aatccaactg gtttcatagg
    18061 tccgaaaagc atcgttttga atcctcgctg tgccattact tcaattggca tacatccttc
    18121 aaaatatttt tctttctcaa aagatttaag ttctgccact tcggcattga ttagtgcctc
    18181 atggaaagct ttgaattcct cttctgtcat cggacagttc aagtaagctg cttctccttt
    18241 gtcatagcgg gacttcaaat atactttatc catatcgatc gtagctttgt ctacgattgg
    18301 tgcagctgca tcatagaaat aaaaaccatc tgaaccattg aatgctttga tgctttctgc
    18361 taatggatga gaagtcaaag gtcctgttgc tactacggtg attccttccg gtatttcagt
    18421 aatttcttcg tttatcactg ttactaatgg atgctctttg acttttcggg taattgtttc
    18481 agaaaaagaa tcgcggtcaa cagctaaggc accaccagct ggcactgctg tttcatctgc
    18541 cgaagtgatt actaccgaat ccaatcggcg catttcttct ttcaataacc ctactgcatt
    18601 agccaaactg tttcctctta atgaattgga acatactagt tcagcaaaat tacttgtgtg
    18661 atgcgcctca gtcgatttga ctggacgcat ttcatataaa cggacaggga ctcctgcttg
    18721 tgcgatttgc caagcagctt cacttccggc aagccctgct ccaacaacat ttaccatttt
    18781 caatgaaaga acctcttttc tattattttt ggatgtcttc ttcgtaatct ccatttacac
    18841 agactacttg tttaccgcct ttgactttct tctcgaccag atatccgtca cattttggac
    18901 aatttctgcc cactggttta tcccaagaag tgaattcaca ttctgggaaa cgggaacaac
    18961 catagaatag tctgtttttc ttagattttc gttcaatgac ttgtccttca tgacatactg
    19021 ggcaagtcac accgatttct tttacgattg gtttcgtatt ccgacaatca ggaaaattac
    19081 tgcaagcata aaacttccca tatttcccta attttattac catcggatgt ccacagacat
    19141 cacaatcgaa tcctgctggt tcatctttga tttgaatttt ttcgattttt tcttccgcat
    19201 tcgtcagttc tttttcaaac ggtttataga aacgatcaac cactttgacc cacgcttccg
    19261 tgccttcttc aattttatcc aaatctcctt ccatttctgc tgtgaaatgg atatcgacga
    19321 tttgagggaa gaattcacag atcagtgaat tgacaatttc tcctagttca gtcggctcaa
    19381 atcttttttg tgtcaatttt acatagtagc gtctttggat cgtatcaagt gttggtgcat
    19441 aagtggaagg tcgccctacc ccgttttctt ctagtgcacg aatcaacgta gcctcactaa
    19501 aacgtgctgg tggttgagta aaatgttgtt ttggttcaat atcaacagat tggactatat
    19561 cgccttcttc aagttctgga agaatatttt ctttctcttc tttgccgtca tctctacctt
    19621 ccacatacac ttgcatgaat cctttgaatt tgatttttga accgttcgca atgaagatga
    19681 caccattttg ttctaatgtc actttcattg tatctaaaat agctggtgtc atctgactag
    19741 ccacaaaacg tgaccagatc aatgtataaa gtttcaattg atctttatct aaatattgtt
    19801 tgagttcatc tggtgtacga agcacactcg ttggacgcac agcttcatgg gcatcttgtg
    19861 cgccttgagc atttttgatc tttcggtgat catgtctaga aaattctttt ccatacgtat
    19921 cttcaataaa tgctgcggcc tctgcttttg ctgtatcggc aatccgggta gaatcagtac
    19981 gcatgtatgt aatcaagccg actgttcctt gtttacccaa agtgattcct tcatataatt
    20041 gctgtgctac catcatggtt tttcttgttc gaaagtttaa cttacgggca gcttcttgtt
    20101 gcaggctact tgtagtgaaa ggattcgcag ggtttctttt gcgctctttc ttttctactt
    20161 ttttaacttc gaagtctgtt ccatcaattc tagcagtgac ttcttttaca ctttgtgcat
    20221 ctggtaattt ctttttctta ccgtcgattc cccagaaatt tgctttgaat ttcttgcgag
    20281 cttttttaaa attaccgtcg atgctccaat attcttctgg aacaaattct cggatctctt
    20341 tttcacggtc aataataatt tttaaagcga cagattggac acgtcctgca cttaaccctt
    20401 tcttgacctt acgccagaga ataggactga tcgaataacc aacgattctg tctaaggtac
    20461 gacgagcttg ctgtgcatct actaaatcta catcgatcgt tcttggttcc ttaaaagctg
    20521 ctttgactgc gtcttttgtg atttcattga agaccacccg atttttttct ttcagatcca
    20581 acccaagtag gtacgctaaa tgccaagcaa tcgcttctcc ttctctatcc gggtcacttg
    20641 ccaagtaaac tttttgagct ttttttgctg cggctttaag gcttttgatg acatcgcctt
    20701 ttccgcgtat agaaatataa tggggttcat aattgttttc aaaatcgata cccattttac
    20761 ttttcggtaa atctcttata tggccaacac tggccattac tttatagttt cgtccaagat
    20821 atttctcaat tgtcttggct tttgcaggtg attctacaat cactaaatat ttatacgcca
    20881 ttactgaatg gactcctttc cattgtcgtg ttcctactat taaaagagga ttcatacaaa
    20941 tcgtagctaa tcatatccat tcagaaaacg tttgtcaaga aaagcaaatg aaaagtatgg
    21001 tgttattctt taaattctgc caagatatct tcacccgaaa ccgtgcaaac tgcaccgtct
    21061 tggatcaaat gatgacatcc ggtagaatgt tctgttaaaa tatttcctgg aacagaaaaa
    21121 actgttcttc caagatccaa tgcttgctgt gctgttatca gagagccgct ttttttcttg
    21181 gcttcaaaga cacatgttcc tttagacaaa gctgcgataa tccgatttct cattggaaaa
    21241 cgatgctttt tcgggccgga ttgaggagga tattcactca aaagaagatg atcatttgca
    21301 atcacctctt gcaagtcacg attttcagca ggatagactt gctctatccc tgttccaatg
    21361 actgcgattg tccgtccacc atgagagatt gctgcttgtt gaccgtatgt atctatccct
    21421 ttcgcgcagc cactgacgat cacatatcca gcttctacca ctggttttag taaataataa
    21481 actgtttttt tggctaaagc agaagtgtgt cttccaccaa caacgcttaa catgttacaa
    21541 gaaagtaaag atagatcacc attataaaac agtacaattg gcggataggt caagtgaagt
    21601 agctgagggg gatatttggg atcaaagcaa gtgataaacg actgtttcga ttggattttg
    21661 ccccagttag cgtgaatttc ctgccaactt ttgcgaaaca gctcccgatg tgtggttatt
    21721 ttacctatct taatgatgtc ttcaaatccg atttctttat aaggatactg catcatccag
    21781 ttagcaagtg cccattttcc ttgactactg attccttttg cataagcaag tttcaataaa
    21841 ttctcttcta tttgatacat cataaaaccg cctttcgtct ctctttctaa taagatacgt
    21901 aaaagcggct gttttttatt gtaaatattt ttttacaggt gcaaaacttt tacgatggat
    21961 tggcgtaatt ccttgtcgtt caaggccttc taagtgttcc tttgttccat aacctgcatt
    22021 atgcgagaaa ccatatccag gataaagcac gtcatattct ttcatcaatt ggtctcgata
    22081 tactttagca atgatacttg cagcagcaat cgacacagat cgtgcatccc ctttgattat
    22141 tttttcctgc tggataggca aatccaaggt catcgcatcg atcaacaaat agcttggtac
    22201 aatggacaat ttttctactg cttggatcat cgctaattta cttgcttcat aaatattcac
    22261 atcatcgatt gtctgctgat caacgatccc gatcccgatt gccagggctt tttcttgaac
    22321 ttgttgataa agaagttctc gctttttctc tgataattgt ttggagtcat tcagccctaa
    22381 tatgatctca tttttcggca agataactgc agctgccacg acaggtccag ctaatggtcc
    22441 tcttcctact tcatcaatgc cggcaatcca ttggtgacct tgtgcgtacc cttgcttttc
    22501 aaagcaaaac atttcttcat atttttcctt aattaatgct tcctttttca atcgtcgttc
    22561 aaaagaagcc agtgcttgct gcacgccttt gcgtggatca tttcttaatg attctagtgt
    22621 aggatcatct attctctgta tgcttttcaa tcgttctttg atactttgga tggattcagt
    22681 catcactttt ttgctccatt tcttcgcaac gatccagtgt gtatcgtcca agttttcctt
    22741 ggcgaatatc atgcacgact aattcgctgc cgcgatcata gtcttcttta tacccacgtt
    22801 ttgctgtaat atccatcagt aattccggtg ccaatttttc ttcttgctcg attgataaac
    22861 cataacgatc gctgattctt cctgaataat atcgggcaaa aaagtctaat ccgtaaatcg
    22921 ctaaatcatc taaatggaca agctggtctt tgatcgcgcc tgtcagcgct agttttttgc
    22981 cgatttcttc atcttcaaat ttgggccata aaatccctgg tgtgtctaac aattccaact
    23041 cattacctaa acgaagccac tgctgacctt ttgttacgcc aggcttattt cctgtctgtg
    23101 caattttctt gcctactagt cgattcatca acgtagattt cccaacattt ggaataccta
    23161 agaccattgc ccgaatagcg cgaggcttga tcccccgagc agcatctctt gcccgttttt
    23221 ctttcaatgc ttctttagcc gcaggtacta gacctttaat tcctttactt tcttgtgccg
    23281 tgatagctaa tgcaagatgg ccttgtttac gaaaatattc ttgccacagc tttgtctgtt
    23341 gtggatctgc cagatccgct ttattcaata aaacaaggcg aggtttttgc tgaatgatct
    23401 gatctagcat tggattacga gaagataaag gtaatcgtgc gtctaccaat tcaaatacga
    23461 tgtccacata tttcattttt tcagaaactt ctcgtcgggc ttttgccata tgtcccggaa
    23521 accattggat ggtcattgtt ctctccattc ctttcatacc ggaatattcc ccggctttac
    23581 ttgttttttt tctttttcaa tataaattca cttttttatt ataaagaaat tccatctatt
    23641 agttaagtga aagtgaacca gtcctcattc tatcacatct tcactttttt gatgatgtaa
    23701 atttttattt tggtttctat atatgaatct aaatttttga caacgtttcc taaataagag
    23761 atgatagacg aacaaaacag aaaggagacg aaacaaatga atagtatggt ttttgttaat
    23821 tttcctgttg ctgatgtcaa tcgttccgtt gctttttatg aaaagctggg ttttaaaaaa
    23881 aatgaagaat tttctactga agaagctggt tcaatggtat gggatgacac tttttgggta
    23941 atgcttctct ctcatgattt ttataaaaaa tttataaaag ataaagaaat agctgataat
    24001 aaaaaaacaa gtggtgcttt gatttcgttt agtgttgaaa acgcggatga agtaaaaaaa
    24061 tttgctcaaa ttgcaaaaga aaatggtggt actttccacg aagtagatat gggaatgcct
    24121 gaagaagaaa tgttttcatt agaagtccaa gatctagacg gaaatacatt agaacccgta
    24181 tggatgaaga tgtaagcaga taactaatct gacgtttttt ataacaaaaa aacaaaggcg
    24241 gatgatacga taagtattct ccgcctctat ttttttcatt cgtacaatct cttttttaca
    24301 gtttataaaa gcagtcttct cacccttttt ttaattgtta gatgccagtg tatgtaaatc
    24361 accaatgtgt catgacacat tggtgatttt atggtatcct tttattatta actgacaaag
    24421 gagagaatat tttgaacact ttgattgcaa aagacgtttt tagattgccc gaaatgaatg
    24481 caagattgtt gtcgacctct gctcttttat tagcccttga tgtcatctta tacaagatag
    24541 cgattggtcc tgcttatttt caaatcacat tcggattttt aagtatggcg cttatgggtt
    24601 atctatatgg accgatctgg gctggtttgc ttgaaatgtt gtcgaacact ttaaatttca
    24661 cgatatttgg ttcaggaacg tttcaagctg cttttcttat cacggctttc cttggtggat
    24721 ttattaatgg cttattttta tatcataaaa agataaacct gccttccgtc atcgctgccc
    24781 aattattgat tatgatccca gtcagccttt ttatcaattc ttggctgatg tctgttttgt
    24841 ttggtgcaga tttcaaagtg atttttctag gtagagtcat caggaatatg atccaaatcc
    24901 ctattcaaat aatggttgtt tattcattta tcaaaacttt agaggctaga aaagtgttta
    24961 aacgagctgt ttgattttac gtactaaggt agtaaactga ttttggatta aacaataaag
    25021 cgtgcagtct caacagattg cacgctttat tgtttctcac tggatccatt ttatttcatc
    25081 aagtggataa tagacaaatc ttgctttacc tagaatatca gttttattga tcgtgccaaa
    25141 cgaacgacta tcttttgaaa ctcttcgatt atctccaagt acaaaataat tatcttccgg
    25201 aagcttggat tgtcccgtta gctcttgtag tgtaaagtcc gtcgtatagg atgcatttgc
    25261 atgatctgat ttcaggtttt tagttagata aggttcctta actactttcc cattgatctt
    25321 caattgatca ttttggtagc tgacattttc tcctggaaga ccgattactc gtttgatata
    25381 aatcgtgcca tctgctaatt gaaaaacaac aatatcaaat cgtctgatct ccgaaaattt
    25441 ttccatcaca accatatcac cttgcttcaa cacgttttcc attgaattgc cttccactgg
    25501 taccgggatg aataaaaatc cccgcaacat gaacgcaagg aatacagaaa caagtaagta
    25561 tttgaataca agccagaagc gattaatata gcgttgtttt tttgtcaatc tctatcaatc
    25621 catccctcgt tttttcattc tttctttatt ataagaaaaa tatcaaaaaa atgcgactag
    25681 atagctgaaa taaaaataat tctttcaatt aggctattgg acaaaaaact tttttgatca
    25741 taaagtacaa aactatctct tatatgtcat gattattttc taaatatttt tcccatgctt
    25801 cgtcaaagat atccatggac ggcaaatagt cgacattcag ttccagataa ttagaaattt
    25861 cttcgtagct agagctgtgc ttaggaaatt ggatgtcttt accggcttct gtagcgaaaa
    25921 cagataaagc atcatgtgtg ccaccgcctc gcagtgtcat taaataatga aaaaagcttc
    25981 gattcaccct tcgttcctcc aattttcttc gataaaggca gcccggcgtg catggtttct
    26041 tttaaaattt tcaggatgct ttttataata ctcttgatgg tcttcttctg ctagataaaa
    26101 tggttgggct ggttcgattt ttgtaacgat tggctgttcg aaacgtccac tttcagctaa
    26161 ctgtttctta cttttttcag caatgatccg ctgttcttct gtcaaataaa agatcaccgg
    26221 gcgataattg tcaccgcgat cctcgaattg tccgaaagcg tcagttggat cagtttgctg
    26281 ccagtaaagt tctactaatt gttcatatga aatcaatgtt ggatcataga taatctccac
    26341 tgcttctgta tgtccagtcg tttggctttt tacttgttca taagtcggat ctggtacatg
    26401 ccctccagta tatcctgaca tcactgtatg gataccagga agcgtgtcga aaggctggat
    26461 catacaccag aaacagcctc ctgcaaatat tgctcgttcc attatgattc cccctctaat
    26521 actactcatc cgatgatttt ttattttctt ttgtcttgct ttcagtactg ctggtgctag
    26581 ttttgttggt atttgagttg tttgaagcat cagaggtatc ttttggcaaa tatagactaa
    26641 accgaatgtc atcatttact aagtcgattt tatctgcttt aatatacatc ccgttttgca
    26701 ttcggaattg atccaaccta agcatgatag tcagatcatc tgtattgact tcgatccaat
    26761 ctggtaattt atagtttctc ttgatcatat tcatcacatc tttgattggc aaactcaatg
    26821 ttccgataga aagacttcta gcttttagtt ggacatttcc gttttccatc acatacggat
    26881 caaaatataa atagaaatcg ataggaaaac ctagtacttc gaaagtacca ttgagtagtg
    26941 cttcattttc caaataaaat ttatattcaa tatcactatc tttttgatac tcactaagga
    27001 aaaagctgat gatttgattg actttttctt tatttgaatt gatcgttaag acaggatctc
    27061 cttgtctttc cgtaagagct ggtatttctg ggagttctgg ttcccgatta gcaaaaatac
    27121 ggctgcctaa aaatacggtc gaaccaagta ctaccccaag aaggataagg aaggcgaatt
    27181 tccagtaatt tgttttcttt gttttgtttg aagatacgtc agatcttgtt ttcatgttta
    27241 ttgatcatcc tccttctcta gccattggtt ttgtgtctcg atcagctgat ctctcactgc
    27301 atttgccatc aattgataac ctaaattatt tggatggaaa tgatcttctt catagagcac
    27361 attatttttg atgccattta gattttctgt cgtgctagtt gtttgatctg ttccttcttc
    27421 tgtgacacct acttcctgat tcaatccttg ataaagcaaa tcattgattg ggataaagta
    27481 gcagttcggc attttttttg tcaccgtttc tgttcctttg ttccaattgt taacaattgt
    27541 ctgcatgtca gtgatctcag gaaagttcaa ataaaatgga ttgtagatgc ctaaaatgta
    27601 aataggtgcg gttttattga gggatcgaaa ttcttccaat agttctgtga cattttcctg
    27661 atagtttttc agtggctttt taaaggaatt gaccgttaac ccgaataaat tattttggat
    27721 aactttcatc aaatcattac cgccaacagt cagtgtgata aaatcagctg ttttgatatt
    27781 gtttcgaatt tcttcttttg tttttactcg ctttaagatc tggtcacttc gttcaccatt
    27841 tacaccatag ttttctgttt caaccgcggt caaattataa cggtctttta gatcatttgc
    27901 gacaagggga acgaatcctc cttgcttggt ttgatctcct actccttcag tcagcgaatc
    27961 tccgatagct atgtagtgaa gtttttcttt tttatttgga tcttctctca cagtagttac
    28021 tggtttcatt agtgggccag ctttcggtat agaagcagct aaacctgcat agatgatgat
    28081 cgcaattaat aatgggaaca aaacgaggat cagatgtcgt ttcgttaatt tcattttttc
    28141 acctcttgta ttcgattggt tctaatgtta tcaaaaattt tatcaaaaag gtagtcttta
    28201 tgaaaaaaga aaacaattat tttcctaatt ttataaagaa aaagagaata agctgcaagc
    28261 ctttcaggct gagggcttat cctcttttcg actaatctac ataatacatg attgcaaacg
    28321 cgtctttacc agtatgcgta gcgataaccg gattcgtatg cagtacaggg atatgcatgt
    28381 ccgggaataa ttcttgcaaa ccctctttga attcttgcgc caattctttt gcatccgcat
    28441 gtgaaatacc gatttgtcgc acatttggca attctttcag ttcatttttc aaattattaa
    28501 accatttatc gaacgttttc tttcctcgcc ccttagttac agggattaat tcagaatggg
    28561 cgaaattcat caccacgcgt atgttcaaaa cactagacag caaaccagtt gttcgactga
    28621 ttcttccacc ttttaccaag ttatctagtg tggatattcc gatgtataat tttgtattgt
    28681 cttgtacttt tttgacttct tcaaggattt cctctactgt tttaccttct tttgctaatt
    28741 cagctgctcg aattacctga aaagataatc cttggtcagt ggtatcactg tcgataaccg
    28801 ttactttcgt ttttgttaga ttactggctt gtcttgctgc ttctactgtt ccactcaagc
    28861 cttttgtcat atggatcgaa atcacttcac tgccgtcttc tcctagctca tcatacatcg
    28921 agataaattc tccaatcggt ggttggcttg ttttgggcag attttttgct tttgccatca
    28981 tttccataaa tctttcgccg tctagttggt catcatcggg atatactgtt ccgtcgatca
    29041 tgatggatag cggcatgaca cgaatgccta aagcatcgcg tacatttttt tccatcgtac
    29101 atgaagaatc tgttacgatt tttacatttg tcattatttt ctctctctct ttctttaaca
    29161 agatgcctta ttcatgttaa actacatgta agacaatttc tatttttagt ataacagaca
    29221 aataatgatt tttcattaat tacacctagt aaaggagccg ttttcatgga aaaaacgaaa
    29281 tttaatcgaa cgtatgaaat attaaatgaa gtgtttaatg cagtcaccca tggaattggg
    29341 actggattga gtatcgcggg actagtggtt cttttagtaa aaggtgccca cttgcattcc
    29401 tccctccata ttgtctctta tgctatctat ggatcgatga tgattctttt atttttaacg
    29461 tctactttgt ttcattcatt gatttttaca aaagcaaaaa aggtgttcca agtattcgat
    29521 catagttcga tttttctttt gattgcagga agttatactc ctttttgttt gctgagtatc
    29581 cgaggatggc taggttggac tttatttgta ttaatctggt tgtttgcgat tcttggcatt
    29641 atatataaag cgttgacgtt gcataaacgg gagagagtat caaaagtatc tacgatcatc
    29701 tatattttta tggggtggct ctgtgtcgtg gctgctgttc ctctttatca ctctcttgga
    29761 atgactggtg ttattttgat ggtagcaggc gggctttctt acacgatagg cgcattcttt
    29821 tatagcttga attctatccg ctatatgcat gttgtttggc atttgtttgt tatgttaggt
    29881 gcaggtttta tgtacttctc tgttttattc tttacttaat aaaaaaaaat aaagctatgg
    29941 atgggacagc tctaaataac agctagtcta tccatagctt ttttatatcg tcaattcgcc
    30001 tgtcccgctt tttacaggat tctcattacg ctgatacgtt tcaaattgat gcggataacg
    30061 atttttttca tctatttctc cttgactagt attgatcagt gaccaatcag accagtcaac
    30121 aggtggaaaa taagcatctc catcgaatac atgatggatg actgtacggt ataatatcgt
    30181 acaaaatggc agaaattctt gataaacagc tgaccctcca gcgatgaaaa agataccgtc
    30241 tgtttctttt tccagagcaa gcacgtcttc cacactatgc atgacatgca cgccttctgc
    30301 tttataggaa gaatctctcg tcaaaacaat cgtctgacga ttcggcaacg gacggctacc
    30361 catcccttcg aaagtttttc gtcccatcac tagtgtattt gcttctgtca tttgtttgaa
    30421 gaatttcaga tcatttggca aacgccaagg aagacggtct tcttttccaa tcaatccgtt
    30481 ttcatcctgt gcccaaattg cagctaacat tttctcatcc tttctgattc taaacagcga
    30541 taggagcttt gatcgccgga tgtgggtcat atccttctaa ttggatatct tccatctcaa
    30601 aatcaaatac tgactgcttt tcctgattca aaactaaagt cggaaatgcg cgtatttctc
    30661 ggctcaattg ttctttcatt tgttcgatat gattgatata aagatgagcg tctcctaatg
    30721 tgtgaacaaa ttcgccaacc gctaaacctg tttcatgtgc aattaggtga gtcagcaacg
    30781 cataacttgc aatgttgaac ggaacgccta gaaacacatc cccactgcgt tgatacaatt
    30841 ggcagcttag ccgtccctct tgaacataaa attgaaacat cgtatgacaa ggaggcaaag
    30901 ccatgctagg aacatcttcc ggattccatg cagaaacgat caatcttcta gaatcaggag
    30961 tctttttgat tgcttcgatc acttctttga tttgatcgat aaagccaccg tcttttgttt
    31021 cccagtgacg ccattgatag ccgtagatgt gtccaagatc gccgtatgtt tcagcaaagg
    31081 aatcatcggt taggatcttc tcgcaaaaaa gcttgctctg ctttttatat tcttcattga
    31141 attcaggatc tgtcaaacat ctatggccaa aatcagtcat atctggtcca ttatagtctg
    31201 gacttttgat gtagcgttca aatgcccatt catcccaaat atggttttta ttttgtaata
    31261 gatagcggat attcgtatct ccttttaaaa accaaagcaa ttcgcttttg atcaatccaa
    31321 aaggtactcg tttcgttgtt aacaaaggaa accctttttg cagatcaaac cgcatttggt
    31381 atccgaataa gcttaatgtg cctgtgcctg ttctgtcttc tttacgatgc ccttcttcca
    31441 acaattttct tcctaagtca agatacgctt gttccatcct ttttcctcct aatcttctac
    31501 ccattcactc aagtattccc accgtgccat tttttcttca agttgtgctt ctgtttcaga
    31561 tacgtcgttt tgcaattctt gtaatcgagt gaaattatct ccttgatgat tcatctcttc
    31621 ttggagcaat gagatttttt cttcaagttc tgcaatctca tcttcaatcg tttcccattc
    31681 tttttgttcc atgtaagata atttcttctt ttcagcaggt tccttgctct gtatttttgg
    31741 tttcgctttt tcagcaggct gctgggtctc tttttgcttc agtaaataac tggacatgtt
    31801 tccgtaataa agttcttgtt ttccgtttcc ttggaatact aataacttat ctgctacctt
    31861 gtccaagaaa taacggtcat gggaaacagt gatcacagca cctggaaaac ttctaaaata
    31921 atcttccaaa atcgtcaatg ttgctatgtc caaatcattg gtcggttcat ccaataataa
    31981 aacattaggt tgctggatca gcagtttcaa caaaaataac cggcgttttt ctccgcctga
    32041 aagtttgcct atcagtgtcc catgcataaa tcttggaaat aaaaatcgtt caagtaattc
    32101 tgctactccg atttgactgc catctgctgt ttttgcttct tcagcagctt cttgtaagta
    32161 agcaatcatc cgtttatctg gtgccatttc ttcattttct tgtgtataat acgcaagatg
    32221 aaccgtttca ccgatagaca ttgtaccgct atccagggga attctgccag ctagaatatt
    32281 aagcaatgtc gattttcccg caccattttt accagtaata cctagtcttt cccgagattg
    32341 aatcagtaaa tctaaatgtt ctagcagtgt ttggtcattt atacggtaac tgccatcttt
    32401 gatttccagt acttttttcc ctaaacgttg tgtcgctagg ttcagctcta aatcatcttc
    32461 ttggtttact tggtacaagt tctcctttag atcttcgaaa cggttgatcc gtgcttgctg
    32521 cttggtgcca cgtgcctgta cgccagccct catccaagct aattcctgtt tataaagccg
    32581 cttgcgcttt tcttcttgtt ctacttctac acgatcacgt tctgcttttt ctaagacgta
    32641 agcttcataa tttcctttat actcgtataa ttttccaaat gaaagttcga agattcggtt
    32701 tgctactcta tctagaaaat aacgatcgtg ggtaaccatc aatagtgcgc cacggtattg
    32761 tttcaaatag ttttccaacc actcgatcgc ttcataatct aaatggtttg ttggttcgtc
    32821 tagtaatagt aaatcgggtt catcaatcaa cacttgcgcc agactaactc gttttttctg
    32881 accacctgat aaagtactga tttttttatc taattcactg attcctaatt tttgcaaaat
    32941 aatctttgcg ttggtatctg tagtccaagc atcttcttta ttcatttgtt cttctgcttt
    33001 agcataacgt ttttgcacat cagggtcttc tccgttttcc cctagttcga tcaatgcttc
    33061 ctcatatgct cgaacagttt ggatcaaggg gctgtttcct tgaaagactg cttggagaac
    33121 agttaattca tcggaaaatt cagctgcttg agaaagataa ccaatacggt aatcagttgg
    33181 ataaaacact gtttgccgat caccgtcgcc gctatcgata ccggcaataa tatttaagag
    33241 acttgtttta cccgtcccgt tcgtcccaat caacccgata cggtcttttt cgtggaccaa
    33301 aaaagaaatc tggtcaaaca aatctttttc accataagtt tttttgaggt cagttacttt
    33361 taattctttc aacatgttcc ctccttatct tggatattgt atcataaaaa tagtgaactt
    33421 caggaaaatt tttttggtat ttgttctttt tgtgttctca aaaaaagaac aggaccgatt
    33481 cgatcctgtt ctgatatgtt ttgtttttta taaaacttga aaatttttac ctttttattt
    33541 tattggactc gtttttttga ctttgctcga aacgcaaatc ggaaagaaaa gttatcagat
    33601 ggtttgttca tcgtataaga ttctaacaaa ttgatattcc tgcgatagct gttcgcagaa
    33661 aacgtcgtga ttttctcagc aacttcgtat tcatcaatga tttttctttc aagataataa
    33721 cctcttagca ttttttttgt aaacagacta tcttgctgga tcatccacga agaaatcaaa
    33781 ttccccgagt tcatttttat tccttcaagt ttgcgttgct ggataaaaaa ttgaaccatc
    33841 gtttcatcat aaatatcagt caagttatct aaactttcaa taatcaactg agtatttttt
    33901 tgatatgtct ctctgatttc ttggatatct tcatcactaa taaatgtctg acgatcagca
    33961 tgtcttcttt gccaaaacat tttcggatgg agaacgattc gcattaacct acggacaaca
    34021 atgaaccaaa agccgataaa agacaaaatc tggcttgtga tagaatgttc gaatcgagaa
    34081 agaaaacggg agtaaaaacg ataaccatta gaagaaagct tgcccgaacg ataactttca
    34141 tccaatccat cccgttcgat cgacaaaatc agtgcttgta tttcttgtac ttcttgcttt
    34201 tcatcatcgg ttaaatcttc caagtacaga tcacgtatcc gttcttgata attttctatc
    34261 actgcttcag tggctaaaaa ttcttttgta ttacgatcaa tttcctttat ttcttttcgc
    34321 aaaacttcaa cgacctcttc taaaatcatc aaagcattca aatccgtgct tttcgcttcc
    34381 tctgtttccg tcagcatagg caagacaatg atccctatga ccaaagtcac taagatgaca
    34441 cccgccgtca gaaacaaaag caaagaccgc tggtaaaaca tcatattatt gattgaaaat
    34501 ggcaaaataa aaatcgtagc caaactgact gttcccttta caccgccaaa tgttaagatc
    34561 aagatctcgt tcaactgttt tttgaacttt ttactgccat ctttgaatac ataaaaaaga
    34621 ctgatagaaa tgaatctgat cacaaaaagc atgacagaga ttaatacgat aatcgctaat
    34681 aaaagaccgt ttggatataa accgtctccc catactggcg agaacacttg cgtcaattcg
    34741 attcctaaaa atataaatac taatgcattc agtgtaaaag caatagttgt ccatgtactg
    34801 tgggacaagc tcgacaattc tgcatcaaac acagagattt tcctaaaacc agaagcttgg
    34861 agaatacctg ctgccactgc agcaatgatt ccagatacat caaatgcctc tgccaataca
    34921 taggctagaa aaggaagcaa aagttcgatc agcagatacc ctgtgacatc ttgtgctgat
    34981 gctttttcga tcaaatgaat tattttttgt ttgaaccaga caagcaaaaa gccgatcaaa
    35041 gctcccccaa tactagaaac tactagactc atccccgcgt ttactgctga aaaagatccg
    35101 gtgatcagcg caccaagagc aaactggaag gcagtaacac cagatgcatc attcaaaaga
    35161 ccttctcctt ccaaaatatg catcgccttt ttagggatat tcactcgtcc agaaagagaa
    35221 ctgactgcta ccgcatctgt cggacctaac gctgctccaa aagcaaagca ggcagcaagt
    35281 gggacacttg gcaacaggaa tgataacgtc gcacctaccc cgacaagggt caaaatgact
    35341 cctccaaatg ccaagaacaa aattgtcccg aaatttttga gaatcgaaga aatatctgct
    35401 ttttctcctt ctctaaataa caatggtgca ataatcataa ctaagaacaa ttcaggttca
    35461 aaatcgattg attgtcccca ctctgtcaga cctaatacca ctccaaggaa aatttggatc
    35521 agtggagctg gaatcattgg caaaatgcgg ctagctatgt tcgataaggt gatcgttact
    35581 gcaaatacaa taactaactc agcaaattcc atcgtccatc ccctttattt tttattttgt
    35641 gtaagcattt ttaaaaattg ttcttttttc tttaaaattt tggtttcgac tacttcaacc
    35701 tgtgtttggt taccctctaa ttcacactgt acacgttttg actccaaacg aagcagatca
    35761 tgtttcagac gttccaactg acgatacatc aatatatttc ttttacgcaa cttacaaagt
    35821 atttgacggc ggtcatccat cgaaagggcg ccatagcgat catgcaacag ttttttttgt
    35881 tgttcaaaac tctctctcat tttccagatc tcctatacac aaacttccat cattatagca
    35941 aagttctttt tggatgaaaa atatttcatt gtttcatcgt ttattgctag ttagaaattt
    36001 ccataaattt ttcaacgcct cattctattc caaatagtat cagatatcaa gtaaaactta
    36061 agaaagataa aagtttctga caaaagaatg tttacttttc cattcctgcc tttcttgttc
    36121 ttttatcaca acaaaaaaat ggggctgcga caaaaatctt gtcacagtcc cttattctga
    36181 ataaacggtg tggaagagac agcctatcag tagtaataag acacatctct ttcacagctt
    36241 catttttgcg taaaaatcga tttattcgaa aaattccccg tatacatctt ctacacgttg
    36301 atctggattg atcacgatat acaagttacc tgttttttcg ctgatttttg ttgattgata
    36361 ttgattgtct aatccttctg ttcctttatc tagatatggg aagtacacaa gatcaggtgt
    36421 gccatttcgg taaaggattt ccattcgctc gatatcttcg tatttcaatg cgcgattaaa
    36481 catgcccatt tccagtccgc ctaggttgat atcatgtgtc gcaactgcgt ccccttcatg
    36541 gaagatttcg attttaaatc cagcacacgg atggatttca acaaattcac tgccattgat
    36601 tcgtccaaaa cttgttgtga tttgtttgat ccaaagatcg ccgatatgac ggcggttgat
    36661 cgtccaggtt tctccatttc taaaataaaa ttttagcgct gtcatttctt tactcattaa
    36721 aaagactcct ttatgatgta atttattctt gtactacctc agtttagcac aaatttatgt
    36781 aagtggtcac atcttatgtt ttttcttcta atgacgtatc tgcccacttt aagtagccaa
    36841 caaagctgag cagatacagt ctagtgtttt ttaaatcaat ttttctttcg ataaaaaatc
    36901 caaaacctgt tttttatcat tttttattct ttgttctacg acggcttttt cagctaattg
    36961 caaagcttca ctaacccact taccaggttt ttttccagtt tcttctagca agattttacc
    37021 atctactgct aattcgctta atgacttgat aggtaaacga tcataggatt ctcctacggc
    37081 atccatctga ggtgtttcgt caaaatagat catcaattct tctacttgca gtgcatgttt
    37141 tttgcctaag aagtacaatt cgaatggttc caaagctcca gtttctcgtt gtcgtagtcc
    37201 ttggacaagt gcttgaacgt ctttaatcat ttggttagaa cacttccacg atttcaaaaa
    37261 ggaacgaatc tcattttctt ttagacccag ttggctgatc aataatgtcc atacttggct
    37321 ctcttctttc aatgggacgg atggtaattc agcaaaacgt aaaagtgctt cgccttcttc
    37381 tttcaaactg ggacagcaaa tgtagcactc tgtttcaata aatgcatgga ttcccgcggc
    37441 ccgttcattt cccaagagca tcttgatgaa ttccacattt atacgttcta cagatatttt
    37501 acctaatagc tcgtggtttt ctttgatggc gtagaaggtt tcttcctcta atttgaaccc
    37561 tagttgactg acaaaacgca acccgcgcat cattcgtaag gcatcttcat ggaaccgctc
    37621 atgaggattg cctacagctc gcaagatctg ttcttctaaa tcttgcagac catcgaacaa
    37681 atcgatgatt tctccatctt ctttcaaagc aaacgcattg atcgtaaaat ctcttctttt
    37741 caaatcttct gccaacgaac gaacgaattc gacatgatct ggtctgcggt agtcctgata
    37801 agttgattcc gtccgaaatg tggtgatctc atattgttca tcattttcta ataccaacac
    37861 agttccatgt tcgatcccaa tatctatcgt ttttggaaaa agctgtttga tttcttctgg
    37921 aaatgcgctt gttgcgatat ccacatcatg gattggctgg ttcagcaaga tatcacgtac
    37981 acttccacct acaaaataag cttcatatcc tgcattctct aattttttca gaactggaat
    38041 tgccttttgg tattccagag gtaattgttt taatttcatt tttccaacct ttcctgcgtg
    38101 tttcttgtac tgagataaag actcagttgc atggtgactg tttgacaagt ccgtttcaga
    38161 gtcttcaagg ccaggaccac ttcatcttgt ttactcgtcc ttacgctcaa agcgattatg
    38221 gtctctttga ttgaattttt ccatgttttt ttcaaaaact tcagttaagt cgatattcaa
    38281 tgaattagcc atgatcatcg taacgaataa aacatcacca agttcttctg ctaccgagtt
    38341 aactggttca gaagcctttt tgcttttttc tccataagtg tggttgactt ctcttgccaa
    38401 ttcacctact tcttcagtta atcgagccat ctgagctaat ggagagaaat accccacctt
    38461 gaattgctgg atatattcat ccacttcctg ctgcatactg tataaagaac gctttttatc
    38521 catctttttc cctccaaaac tatcttacca aaactttaac gcaaatccta gataagagca
    38581 gttgagaaaa tcgaatttcc atgctacatt tagaaaggaa tttctaaatg gaaattctgt
    38641 gaaaatacat aattgaaagc tggaattcat atggtcaaac gaaaaacagt aaaagaagtt
    38701 ctttttatca ttataggaac aagtatttat gcatttggtc ttgtttactt gaacatcgct
    38761 aatcatttag cagaaggggg cgtctcaggg atcaccttga tcttaagagc tttattcgga
    38821 attgatccag cttatacgac tttattaatc aacatcccat tgattttact aggaggaaag
    38881 atcctcggta aacgttcctt ggcctataca gttctaggta cactttcttt gtcattcttt
    38941 ttatggatct ggcaaagggt tccactagaa atcaatttac agcatgatct actgatcgtt
    39001 tctctacttg cgggtttagt tgcaggtgta ggaagcggga tcgtctaccg catgggtgga
    39061 acaacaggtg gcagcgatat tattgctcgg attttagaac aaaattacgg catcactatg
    39121 gggcgttccc tattggcatt tgatatcatc gtcttacttg cttcattaac ctatatcgac
    39181 ttgaaacgta tgatgtatac gttgattgtt tcgtatgttt tcagtcgtgt gattgattcg
    39241 atcttagatg gcggatattc tgcaaaaggt ctacttgtcg tctccaacaa aagcgaagag
    39301 attgcaccac tactgatgac cggtctgcaa agaggtgtga cttttctttc tggagaaggc
    39361 gcattctctg gtaattcaaa aaaaatcatc tatatggtcg ttagctctag tgaattaact
    39421 gaagctaaga ggatcgtcca cgagattgac gaaaaagctt tcctttcaat catcaatgtg
    39481 catgaagtgg aagggcaagg ctttacttat ttgaagccac agacaagatt actgaaaaaa
    39541 ctataagaaa aaagacaaag ataggctatg aggaaa
//
LOCUS       DAFKHN010000020        38129 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFKHN010000020 DAFKHN010000000
VERSION     DAFKHN010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 38129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.020"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(61..2424)
                     /locus_tag="LY912_001031"
     CDS             complement(61..2424)
                     /locus_tag="LY912_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HBM6954742.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2872..3093
                     /locus_tag="LY912_001032"
     CDS             2872..3093
                     /locus_tag="LY912_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6954743.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="LY912_001033"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="LY912_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBM6954744.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="LY912_001034"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="LY912_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBM6954745.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="LY912_001035"
     CDS             complement(5894..6205)
                     /locus_tag="LY912_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBM6954746.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="LY912_001036"
     CDS             complement(6202..6495)
                     /locus_tag="LY912_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBM6954747.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="LY912_001037"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="LY912_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBM6954748.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="LY912_001038"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="LY912_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBM6954749.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="LY912_001039"
     CDS             complement(8333..12685)
                     /locus_tag="LY912_001039"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBM6954750.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="LY912_001040"
     CDS             complement(12897..14606)
                     /locus_tag="LY912_001040"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBM6954751.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="LY912_001041"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="LY912_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBM6954752.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="LY912_001042"
     CDS             complement(16103..16903)
                     /locus_tag="LY912_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBM6954753.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="LY912_001043"
     CDS             complement(16900..17712)
                     /locus_tag="LY912_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBM6954754.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="LY912_001044"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="LY912_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBM6954755.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /locus_tag="LY912_001045"
     CDS             complement(18467..19189)
                     /locus_tag="LY912_001045"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBM6954756.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /locus_tag="LY912_001046"
     CDS             complement(19325..20206)
                     /locus_tag="LY912_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBM6954757.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="LY912_001047"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="LY912_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBM6954758.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="LY912_001048"
     CDS             21446..21925
                     /locus_tag="LY912_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBM6954759.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="LY912_001049"
                     /pseudo
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="LY912_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
     gene            23226..24011
                     /locus_tag="LY912_001050"
     CDS             23226..24011
                     /locus_tag="LY912_001050"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBM6954760.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /locus_tag="LY912_001051"
     CDS             complement(24357..26048)
                     /locus_tag="LY912_001051"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBM6954761.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="LY912_001052"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="LY912_001052"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBM6954762.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="LY912_001053"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="LY912_001053"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBM6954763.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="LY912_001054"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="LY912_001054"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBM6954764.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="LY912_001055"
     CDS             30332..31033
                     /locus_tag="LY912_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBM6954765.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="LY912_001056"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="LY912_001056"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBM6954766.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="LY912_001057"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="LY912_001057"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBM6954767.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="LY912_001058"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="LY912_001058"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBM6954768.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="LY912_001059"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="LY912_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBM6954769.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="LY912_001060"
     CDS             complement(34528..35508)
                     /locus_tag="LY912_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6954770.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="LY912_001061"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="LY912_001061"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBM6954771.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="LY912_001062"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="LY912_001062"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBM6954772.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT        10309 a         8173 c         6753 g        12894 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgta acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag agggcgttac
    34681 atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc ttcaatcaac
    36061 aattttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaatcggc
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta gaagagaaca
    37681 cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt atggtgaaaa
    38101 caaacaaagt aaaatttcgt aaattcata
//
LOCUS       DAFKHN010000021        36354 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFKHN010000021 DAFKHN010000000
VERSION     DAFKHN010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.021"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..574)
                     /locus_tag="LY912_001063"
     CDS             complement(<1..574)
                     /locus_tag="LY912_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBM6954773.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEH"
     gene            complement(580..1839)
                     /locus_tag="LY912_001064"
     CDS             complement(580..1839)
                     /locus_tag="LY912_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBM6954774.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIAPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(1841..2887)
                     /locus_tag="LY912_001065"
     CDS             complement(1841..2887)
                     /locus_tag="LY912_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954775.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQRPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(3122..3397)
                     /locus_tag="LY912_001066"
     CDS             complement(3122..3397)
                     /locus_tag="LY912_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBM6954776.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(3640..4950)
                     /gene="der"
                     /locus_tag="LY912_001067"
     CDS             complement(3640..4950)
                     /gene="der"
                     /locus_tag="LY912_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBM6954777.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(5132..6361)
                     /gene="rpsA"
                     /locus_tag="LY912_001068"
     CDS             complement(5132..6361)
                     /gene="rpsA"
                     /locus_tag="LY912_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBM6954778.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(6496..7176)
                     /locus_tag="LY912_001069"
     CDS             complement(6496..7176)
                     /locus_tag="LY912_001069"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBM6954779.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAIQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(7225..7860)
                     /locus_tag="LY912_001070"
     CDS             complement(7225..7860)
                     /locus_tag="LY912_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBM6954780.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(7926..9329)
                     /locus_tag="LY912_001071"
     CDS             complement(7926..9329)
                     /locus_tag="LY912_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBM6954781.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGFLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKHQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(9316..10347)
                     /locus_tag="LY912_001072"
     CDS             complement(9316..10347)
                     /locus_tag="LY912_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6954782.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYERILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            10378..10599
                     /locus_tag="LY912_001073"
     CDS             10378..10599
                     /locus_tag="LY912_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBM6954783.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(10764..11501)
                     /locus_tag="LY912_001074"
     CDS             complement(10764..11501)
                     /locus_tag="LY912_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBM6954784.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGNSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(11655..12995)
                     /locus_tag="LY912_001075"
     CDS             complement(11655..12995)
                     /locus_tag="LY912_001075"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBM6954785.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(13232..14755)
                     /locus_tag="LY912_001076"
     CDS             complement(13232..14755)
                     /locus_tag="LY912_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBM6954786.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(15133..15744)
                     /locus_tag="LY912_001077"
     CDS             complement(15133..15744)
                     /locus_tag="LY912_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBM6954787.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIP
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(15867..15991)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16073..16789)
                     /locus_tag="LY912_001078"
     CDS             complement(16073..16789)
                     /locus_tag="LY912_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBM6954788.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(16795..17364)
                     /gene="scpB"
                     /locus_tag="LY912_001079"
     CDS             complement(16795..17364)
                     /gene="scpB"
                     /locus_tag="LY912_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBM6954789.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISFEEDVSPDLFFDGMNKGE"
     gene            complement(17348..18145)
                     /locus_tag="LY912_001080"
     CDS             complement(17348..18145)
                     /locus_tag="LY912_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBM6954790.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(18115..18486)
                     /locus_tag="LY912_001081"
     CDS             complement(18115..18486)
                     /locus_tag="LY912_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBM6954791.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGVYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(18505..19392)
                     /gene="xerD"
                     /locus_tag="LY912_001082"
     CDS             complement(18505..19392)
                     /gene="xerD"
                     /locus_tag="LY912_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBM6954792.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(19488..19961)
                     /locus_tag="LY912_001083"
     CDS             complement(19488..19961)
                     /locus_tag="LY912_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBM6954793.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(20066..20929)
                     /locus_tag="LY912_001084"
     CDS             complement(20066..20929)
                     /locus_tag="LY912_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBM6954794.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(21125..23266)
                     /locus_tag="LY912_001085"
     CDS             complement(21125..23266)
                     /locus_tag="LY912_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBM6954795.1"
                     /translation="MMKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDA
                     AMQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIE
                     KNEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHRED
                     TKEEHAKELLKMISEKIAQENKVEPEHEAEKDTEKDISGVNAAGKESLKTNDLKTNDL
                     KTDIPEKTETLSEKQSEDEKSNGLPEADKKEMLEKADKKATESDGINNEADAETQSAS
                     EDSTALEAKIEKEENQPELIEAETEPITIVPNTEKTPQESNPEKKDLDKTQKKKSKKV
                     PYLALAAVLLLGGGGWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFI
                     RADMIHQDLSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDH
                     LADDIKLKADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVV
                     DSATRDQYKTAKEAVEKVKNTDLSAQLNEQLQQVDKMLTDKEKKEEEEKKKAEEAKKA
                     EKAKKAAEEQAKQAAQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARAS
                     DIADASNPAWTWAPGVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKS
                     ALMKGIGESALPFYIVTINCKTGWFGGNGSN"
     gene            complement(23483..24592)
                     /gene="rpoD"
                     /locus_tag="LY912_001086"
     CDS             complement(23483..24592)
                     /gene="rpoD"
                     /locus_tag="LY912_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBM6954796.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(24616..26457)
                     /locus_tag="LY912_001087"
     CDS             complement(24616..26457)
                     /locus_tag="LY912_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBM6954797.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(26639..28954)
                     /locus_tag="LY912_001088"
     CDS             complement(26639..28954)
                     /locus_tag="LY912_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBM6954798.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(29139..29999)
                     /locus_tag="LY912_001089"
     CDS             complement(29139..29999)
                     /locus_tag="LY912_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBM6954799.1"
                     /translation="MEKRQKMENQKVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(30058..30690)
                     /locus_tag="LY912_001090"
     CDS             complement(30058..30690)
                     /locus_tag="LY912_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBM6954800.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            30857..31618
                     /locus_tag="LY912_001091"
     CDS             30857..31618
                     /locus_tag="LY912_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBM6954801.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31644..34235
                     /gene="mprF"
                     /locus_tag="LY912_001092"
     CDS             31644..34235
                     /gene="mprF"
                     /locus_tag="LY912_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBM6954802.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(34423..35610)
                     /gene="tuf"
                     /locus_tag="LY912_001093"
     CDS             complement(34423..35610)
                     /gene="tuf"
                     /locus_tag="LY912_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBM6954803.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            35978..36334
                     /locus_tag="LY912_001094"
     CDS             35978..36334
                     /locus_tag="LY912_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBM6954804.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT        10097 a         7697 c         6246 g        12314 t
ORIGIN      
        1 tatgttcact tacccggtta cttttctttt gtgtctgcaa aaggatcttt cggttaactt
       61 catcagataa tttcaaaaaa gcatccctat ctccatcttc tagtgcttga tcgatttgag
      121 cataaagcat ttttagtttt gcctcttctt ctttttcttg aaaatatcgt tcaattaatt
      181 cagtatcttc ttcactgact gaagaatccc aagaagaaaa tggattgtct tctaagatag
      241 atagatattc tcttgtctgc caagcatttt cgaatataca ttccacatat aaaggctttt
      301 tccaattcaa acggatttca tgaaaaatct ggtctgtgtc cgtaaattct tttccctgca
      361 aaaacaattt catgggttcc ccttcaacag atagatcact gatctgcagt cctcgatccg
      421 caaaattcgc cccttcaaca aagtggacat tgcttaaaat cgcttcatga ttggcaagat
      481 aattcaagat ccaaaaaact tctcttcggc taaaagatac atgattgacc atccacgtta
      541 aaaaattctt cttttcccgt acatcaatta gcatttttct cacctctctg ttaggtcatc
      601 taataatgac agtgcctcca tatctcctgg ttcaagtgtt aaataataag tcaataattc
      661 ttgcgctctt ttcagctgcc cttcttctct taagaaaaag gcatactctt tcaagaaatc
      721 tggttcatgt gatagttcat gataagcctg ttcatagtgt acagctgcaa cggtaaagtc
      781 ttctaattca ttataagcat gggctaggtt ccattctgca taaggattag cagtttcttc
      841 catctgattg atcacttgta tcacatcttc atatctttca tcatccaagt aaagattgct
      901 taaagtaagt aatgtttcat cttgtttgtc tcctacttct aaagctttca gtaaaagttc
      961 ttctgctcgc tgtctatcat gcagacggaa agcattttcc gaggccaggt gataaagttc
     1021 gacttggtaa ggattttctt tgattccttc ttctaacact gtttgtgctt cttcaatcat
     1081 ttcttcttct tgaagagctt gtcctagata tagatataac gattgataat gcggattaac
     1141 ttctcgaagt tcttccagat agttgattgc ctgctgattt tctttcaatt gaagattcgt
     1201 aaaagctagc tggaacagtc gatcatctgt cctttcttct ttcagtgctt cttctaaagg
     1261 tgcgatagct gcttcgaatt ctccttgcat acttaaggat tgtcctaaac gttcctgcat
     1321 cgagattcct gaaatttcat ttatcccgct tgccaacaat gtttcataaa ccactgctgc
     1381 ctctttgaaa cgatcaactg aaaaatacaa ttcagctagc gcaaactgga tcaatggttc
     1441 atcaggaagc aacccagctg cttctttcaa ttttgcttca ctcacttcag ggattccgat
     1501 aacttggtac aaatcagcta tcgccaataa gctttgcgga tagtaatcac tttgcttatc
     1561 cactttttcc aggtattcaa aagctaagtc gatctcatta tcttcgattg caatttctgc
     1621 taacgggatg ttcagtccgt cattttctgg gtattggttg atcagttgtt caaaaatctg
     1681 ttttgcttcg atcaaaaagc caatagccag caattcttcg cctagttcag ctaatatatc
     1741 tgctgggtct tcttttaatg ctttttctaa aaagatttgt gcttgtgaca agtcttcatc
     1801 tgataaagct tgcaacattt tttcgctatt tgtattcatt tcaattccct cttatctcac
     1861 tgacgatttg ttgaaatacc gtcattgttc tcaataattc tttttcgttt ggacgttggt
     1921 atccgtctat tatacctatt ttttctaaaa caagtatttt tttgcttttt tctgccaaaa
     1981 aaagaacttt ttccaaatac tccatctttg aaatctgttc cagccagtgg attggatagc
     2041 caagcaagtc cagccacaca aaaaagtttt ttagttggaa atcaaaagga tatgcttgga
     2101 gattccacac gaaatgaaac atcattccta aaaatttttt catactagca gaaagtagat
     2161 ggccattttc ggtcagataa aaagcttgtt caaacagttt accataattt gacaggtttt
     2221 ctgcctctaa ttgataaaaa tagatcattt cttcgatcat cccggcaaac ggccgagtcg
     2281 ttaattgctt tttatttgga tagtttttat acagattttg caaaaaacga tgatcacaaa
     2341 tcattccgca acagataaaa gtcaaaaagt caatctgctt tccgtccact tgccgctcgc
     2401 tgattgtttg atcataaacg atgcgttctg gcagattgat ggtttgcagt actacacgat
     2461 ttggtagctg caaaatcgtc cgctgcggtg ttaatgctcg gcttagagaa cggatcgata
     2521 cagggatcat ccatagtgat gaatcaaggg ttgtatgttt ttgaaaaaaa cctgccagat
     2581 ccatgatccc ttcatttcca aatccgatga taaacatgga ttgattttcg ggatagcgtt
     2641 tgacgaaatc aagcaggttc tttaattctg ttaaatgatt gcattgagtg ttggcacaaa
     2701 tataccagtc attgtttgct tgatttgcaa ataacgggtt gatcttatct gcaaacaaat
     2761 cataatagcg ctgattcgtt aaaaataaga ttggctgatc aatggaaagt tctcttagct
     2821 ggctgactag cgtttctccg taaaacactt tcgtcaacgc atcttctact tgataatcaa
     2881 gttccatacg catccctcct cttcttattt ttattttacc attagtaagc aaattctaga
     2941 aaagataaga gcaaagctca cctcataact tggaaataaa taaaaattaa ataaaataca
     3001 tgtgttttct atgtatgaca tacggattcg gaatctctgt ctcttattta ttccttttct
     3061 gctaggaaat aaaaagagaa gcacttgtag ccctagagcc acaagcgctt tttcaactgt
     3121 cttatttaac agcgtctttt aatgctttac ctggtttgaa tgcaggtact ttgctagctg
     3181 gaatttcgat ttcttcacca gtttgtgggt tgcgaccttt gcgagctgcg cgttcgcgaa
     3241 cttcaaagtt accaaaaccg attaattgaa ctttttcgcc gttagctaaa gcatcttgaa
     3301 tagttgaaaa tacagcatct actgctgcag ttgcatcttt tttagttaaa tcagtagctg
     3361 aagcaacttt ttcgattaat tctgctttgt ttgccatgga tagattcacc tcctccacaa
     3421 gagatatgat agaaatatca tttagttaaa actttctgag tggtccagaa gtttaaaaag
     3481 aaatattgat taacttcaat attctgttat cacgatatca tatgaaccgc ttaatagcaa
     3541 ggtttttacc aattttcaca tgcttttttt agtcatagaa acgtaacaaa cgaaactgtc
     3601 tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc tattttctcc tacgagggat
     3661 aattcggatg gacgtccctt caaaagtaaa tgcttttctg atttgatttt ctaagaaacg
     3721 ttcataagaa aaatgcatca attcctcttc attgacaaaa acgacaaatg taggtggttt
     3781 gacagcgact tgtgtagcat aaaaaatctt caggcgtttt cctttatctg ttggtgttgg
     3841 attgattgct acagcatcca taatgatatc attcaacaca gccgaagaga tacgaagatt
     3901 ctggttcata cttacttgtt cgatcatttc aggcagacgt tccaaccgtt gtttagtcac
     3961 tgcagaaaca aaaacgattg gagcgtaatc aagataccgg aattcatcac gaatctcttg
     4021 ttcgaaatca cgcattgtat tggtttcttt ctttacaaga tcccatttat tcacgacgat
     4081 aataattcca cgaccagctt catgggcgta acccgctact cgcttgtctt gttcccgaat
     4141 cccttcttca gcattcagta ccatcaaaac gatatcagaa cggtcaatgg cacgcattgc
     4201 acgcatcacg ctgtattttt cagtattttc gtatactttt ccgcgtttac gcataccagc
     4261 tgtatcgatc attaagaatt tctgaccact ttcagaaacg aagtgggtgt cgattgcgtc
     4321 tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct tctcctaaaa tcgcattgat
     4381 caaagaggat ttaccaacat ttgggcgacc aatcaaacta aacttaatcg tgtcgtcgtc
     4441 ctcttcttca gtctcttcag agaaatactt cactgcttca tctaaaatat caccaatccc
     4501 tagtccatgg cttcctgaaa caggataagg atcgcctagc cctaaggaat aaaattcata
     4561 gatatcgttt ctcatttctg gattatctac tttattgact gctaaaatca ctggtttatt
     4621 acttctgtat aaaattttcg caaccatctc atctgcgtct gtcacgcctt cgcgtccgct
     4681 gactacacaa atgattacat ctgcttcttc aatcgcgatt tctgcttgat gcttgatctg
     4741 atccataaag ggttcatcgc caagatcaat tccgcctgtg tcgatcacgc tgaattctcg
     4801 acctaaccat tcaccttttg cataaatacg atcacgagtt actccaggag tatcttcgac
     4861 aatcgagata cgctcaccag cgatgcggtt aaaaatcgta gacttaccga cgttcgggcg
     4921 gccaacgatt gcaattgttg gatttgccat attatttcct cctcacaagt ttccaatctc
     4981 acttagttta acgaatgcat tgccaacttt caagcataga ttgtcaatta aacgaagtat
     5041 ttttattcct tattgaaata ctaatcgctt ttcaaaagaa aaactgagac aaaagcagct
     5101 gctttcatct cagtcacaga tacaaaatca attatttttc agaatcatcg gttgcttttt
     5161 cttctacttc ttctttcaac gcatcaccta aaatgtctcc catagtaaat ccagtatttt
     5221 cttctggtaa ttcataagac tcaacatttt ttggttcttc ttctgaagct ggtttttctt
     5281 ctaaagcttt gatactcaat gcaatacgat gttcttctgg atggatctct aatactttca
     5341 ctttcacttc gtcaccttca tgaagcactt catgtggtgt cgcaatatgt ttatgtgaaa
     5401 tttgagagat atggactagc ccttctactc cagggaacac ttcaacaaag gcaccgaagc
     5461 ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac tggagctttt gtatcgattt
     5521 ctgaccaagg tccaggctgt gtgtctttga tggacaagga aacacgttct tgttcaggat
     5581 tgatagacaa cactttgaca tttacatcat cattgacagc caatacatca cttggttttg
     5641 ctacatgact atgtgaaatc tctgagacat ggactagacc gtcaattccg cctaggtcga
     5701 caaatgcgcc aaaatcagta agacgtgcaa cacgtccact gagaacatct ccctcatgga
     5761 tagttgaaag aatttctttt ttcttttctt ctctttcgtt ttccactacc gctttatgcg
     5821 ataagatcaa acgattttct gatggttcga tttcgatgat tttaaagctc aatgttttgc
     5881 ctttatagtc tgaaaagtct gcaacaaaat gatcttccac cattgatgca gggacaaaac
     5941 cacgtacacc gacgtcaacg actaaaccgc ctttgacaac atttgtaaca ggtgcttcga
     6001 tcaccttgcc ctcttggaaa tctctttcga tatcttccca aactttttta gcatctaaac
     6061 ggcgttttga aagtaggtag ctgccgtttt ctttatcttt gccgatcgta ctgataacga
     6121 ctaagtctaa tacatcaccg acttttacta cttcgctgat atcttctacc ggcaaagttg
     6181 ataattcttt tgccggaacg actccttcaa ctccagcccc ttcgattccg acaatcactt
     6241 gtttgtcttc aatgactaaa acttcgccct taacaacatc gccaactttt acttcttgta
     6301 cgcttttcat tgcgtcttcc attgactggt tgttctcttg attttgatca aattctgtca
     6361 taacacttgt cctcctaacc aacattctgc cgtaagtacg gtactgtttt tagtttaatt
     6421 gattattcaa aaaaaataaa gcgatttcgt tcgttttcct tgaaaaaaca attgtttttc
     6481 attttttttc ttaatttaaa aaagaagata accttttttc aaaacaacag cttttattgc
     6541 tgcaacgact tctggaatcg atttgccagt cgtatcgata cgaacagcat cctctgcttg
     6601 cttcagcgga gagacgtccc ttgttgaatc ataatggtct ctttcctgta tctctttcgt
     6661 cagtgtttca agatcagtcg gaattccttt ttcttggttc tctttgaaac gtctttctgc
     6721 acgctcactt acgcttgcta ctaaaaagat tttcacttct gcattcggta atacagctgt
     6781 cccgatgtct cttccgtcca tgacaacgcc accgcgttcc cctatttttc gttggatagc
     6841 aactaattct tctctgactt ttccatgtgc agagacttca gaaacagctt ttgtgacatc
     6901 tggttgacgg atttctaaag tcacatcttt tgatgctatg aatacatgct gtccatcttc
     6961 ttgttgcgaa aaagagatag gatacttttt gatcagcgaa actagccctt cttcatctga
     7021 aaaggataca ttgttcgtaa tagctaaata agttactgcg cgatacatgg caccggtatc
     7081 tgtataaata taattcaatt cttttgctaa tatcttggca acggtacttt tcccagatga
     7141 agcaggcccg tcgattgcaa tactgatttg tgtcatgata taactccttt ttctcaaaaa
     7201 aaaagccgca aagcgcggct attattattt aattcttaat tcttgaccag ggtaaagcat
     7261 aaagttgttt ggatctaagc cattcaattc aaacaattga tcagtggtga tccctgcacg
     7321 ctcagccact tgttttggac cttcgcctgc ttgaacagtc gttgttgaac cggctgcagc
     7381 tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa tcccctgctt gataagttgc
     7441 ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg ctttctgacg ttacacctgt
     7501 atcttgagac acagtagatt cttccgcgat tgtactagat tctactgttg aagtctcagt
     7561 tgactcctct tttgttgtac ttgtagaact ttctactact gatgtcgaag tttcagaaga
     7621 agttgctgct gttgcattgt tgcttgatcc atttctgatc cagaaataag cacctgctgg
     7681 aatagcgata cataagacca gtaaaatcaa aaatagcgaa agaaataatg tatttccttt
     7741 cttttgttgt ctctgagaac ttcttgatga aacttcatca tctgtatcgt agattggttg
     7801 ttcccatggt tcttgtgttt cgttattttc tgtagattga tgtctatctt ttctgctcac
     7861 tgttttacct cctaaactct atcgtgtgta ttataccata ggaaaaagtg tcttgtccta
     7921 aaaaatcaat gttccatgtt ttttttaaat aaatttagta aaatcgtttc ccaatgaagt
     7981 tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt ctgcttttgc tccatcaata
     8041 tcacaacaat tctgcggctt ttcggagagt ttttcgccaa aataagctaa gatgaatttt
     8101 ctgcggcagt tttcttcatt aatatagcga agcatctgct gcaggcggaa ttctttttct
     8161 ttttcctgat gtttgagccg ttccacccaa ttttctggtt tttcagactg ctggatcagc
     8221 tccatccatt ttttttgcag ctcatcaaag ggagcttgct ctgtggcata ttccaaataa
     8281 agctcaaaac tttgtcgctg ttctctagaa agttgattaa agaaataatg gatacgttca
     8341 tccccacttt gataaaaaag aattgctgca ctttcttcct gatctctgcc tgctcgaccg
     8401 atttcttgta catagttttc tagactgtct ggcaaatcat aatggatcac ataacggata
     8461 tcagatttat cgatccccat accaaatgca ttcgtagcaa tgagaaactg cagctgattt
     8521 tttacaaact gctgttgaag ttgtcttctt tgagctgcat caagaccacc gtgatagtat
     8581 ccaactgtaa aacgttccct gaataaatga tacaatcgtt cgacttcttt ttttgttgca
     8641 caataaatga ttgccgctcc ttgtgctctt tccatgaagt gttcaagttc ttgttctttt
     8701 tgctgcgttt tccgaacaaa aagcgagata ttttgccgat tgactgattg tctgatctct
     8761 tttggtggtc gatcaaatag tacatgacgt atatctcttg ctactaaatc tgttgctgtc
     8821 gccgttagtg ccagtgtgac cgggtttcct aaaagctttc ggatttttcc taactgttga
     8881 tattctggac ggaaatcaac tccccattga gacacgcaat gagcctcatc tactacatat
     8941 aacgcaatat tttgtttttt cagatgctct aaaagagaag gattagtcaa catttcggga
     9001 ctcaaaaaca aaaatttata ttgcgataga tgacggagga cgtatcttct ttcagattgc
     9061 gaaagtaaac tattgaaagc agctactcgt ttctcccctc gtttttgtaa ttgcgtcact
     9121 tgatcttcca ttagagaaag cagcggtgac acgatgatga ccagaccttc cattaaaaac
     9181 cccgtcaatt gatagcaaag gctttttccc gttcctgtag gcaaaatagc gagagtatct
     9241 tctccatcaa gcaacgcctg aatgatttct tcttggccgg gacgaaatga atcaaatcca
     9301 aaatattttt ttaattcatt tattaacatt ctgtatcgct tcctttctca atagatagat
     9361 ttgatacaaa cgaaattctc cataatctaa ttgtccatct acattccatt cgctaaagcg
     9421 ccactctcgc acggaatcct tatttggttc caaacgttcg attgtttctg cagagagaat
     9481 ccgctcgtat ggaaaatcat caaaaaacaa ggcccactca ataagatgat ctgttactgt
     9541 tcctcttttt aaatgacgga ttgccataat ctggtcaatt gtctgaccat tcataaacat
     9601 ctgcttggtg atcatcatgc tttgattgaa attttgctgt aataatgaat cgatcaaagc
     9661 gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac aaaaggtgga tacatctgct
     9721 ttgttgcaga taaaccgctg actcatcatt gttttttgcc agctgataag gaagcagccc
     9781 tgttcgctca tttccagata attggttagc taaaaaatct gctgcttctt ctggtatctc
     9841 cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc aaaatttcac gtggcaattg
     9901 gctttcacta agccattttt ttagttggaa agtataaaaa ggacttgtct ctgctggaag
     9961 atagtcttga atacccgttg ccagattaga aattacttga acagcaaatt taatgagccg
    10021 ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc aaaccagtat gttctatttg
    10081 atgttcggac aacatatcag cccctgcagg cgttagcttt gcttcatttt catttatttc
    10141 gatccaacct tgctgcgcaa ttttttgcaa aatttgataa aacttatcct gcttcaattc
    10201 tggaaaactg ttatggataa acaaaagttc gtgggtaaat ccataaataa gtactgaagt
    10261 cgttcgtttt cccacaagga gttggtaaag agaactaatc cgcagcttgt gtcctgatga
    10321 aaatagcgat aaaataaaaa caatcatatt attctcctta agttaggatg gttagaaatg
    10381 tcactactat gtaaacttgt acctgaacgc tgtattgcat gcggtctttg tcaaatcgaa
    10441 gcgccagata ttttcgatta tgatgaagaa ggaatcgttt tatttgccca agaaccagag
    10501 gctcatcaac agttcgtgat gccggaagaa gaaacatatg taaaaaaagc gtatcaaaaa
    10561 tgtccagttc gagcgatttt attagaaaat aaaatataaa tataaacgaa actttaaaaa
    10621 cgtacactaa gttctctaaa cttgaaaata agccgggatc tgtttctctt gttccgtgaa
    10681 atcccgactt attttgaaag attcatttgc tatctatagt taattgacta gttttttcac
    10741 ggaccctata ggacccattt atattatttc aactttttca gccagttttc caatgtattg
    10801 acgatcacag tttgctggtc tgcgttagaa atttctgcct ctccatctcc tttttgctca
    10861 ccatagctgc caaaacctcc atgatttccg ccattgattg atacatactc tgttctttcc
    10921 ggtaaatact gcttagcttc ttgataagct tcctgattca atactttatc ttttgtcgcc
    10981 gtgatcgata aaacaggaac agctgattct gtcaatgttc cttttttgtc gggataactt
    11041 gccatgaaga ataccccttt taaatgtttg tctgaatgat tcttattgac ataacgactt
    11101 gccattacgc cacctaatga atggccaccg atcacataat cggaatttgg aaaatcttct
    11161 ttgaccttat ccgctttgtt tccgcccatc actgctagat caagtggcat tttgacaata
    11221 gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa tactataact ttctggctct
    11281 acgagagcac caggataaaa aataagtaat ggagaatttc catgattctt tttctctcct
    11341 tcaaaaaata agtaatcttc tttgtttttt ccttctttta ccaacacttg cgcttctgac
    11401 gatggttcgt acgtattttg ctgtatatag taataaccgg ctccaccgag taatcctaaa
    11461 atgatgacta agccaattag tattcgtcta aatattttca ctttctccca ccttttctat
    11521 ctgagtgacc cctttttctt aatcaagtat gattatacct taaaaaaaat aagagagaaa
    11581 tgcaaacttt ccagcatcaa ataaaaaaag acggaatatc catttgaata tccgcccttt
    11641 ttgtatgttt atttttattt agcacataaa cgatacacag cttctgcata aatttccatt
    11701 gctttataca tactacttaa ttcccatcgt tcattcgcct ggtgcataaa gtcaggagta
    11761 tcagggaaca tcgcaccgaa tgccacacac tggttcatcg tacgagcaaa agtagcgccg
    11821 cctgatacaa acggttcagt catgtctcca gtaatatcgc gatatgtccc caatagattt
    11881 ttcactaact cactgtctag tggcacgtat aatgaatcaa ggaagtcaaa ttcttcataa
    11941 gtcaacccat atttttctgc tgttttagtt aatttagcta ctaaatcatc tttcttgaat
    12001 gtaacaggga ttctcatatc tacaccgatt tttgtttgtt ctggtgtgat ttccaaactt
    12061 gcaaagttca tcgttagctc gccggattgt tcatcttctg ttttgcccac gacagcttca
    12121 ccagttgcat tttcttgaac taattttcct aagaaattga ttgggccaaa atcgaatact
    12181 tctgaaagag caattgccag acgagaaata gcattcactc cttgtgctgc atctttcgcg
    12241 tggatacttt taccaagaac gacgatgcct tcaccttgtt cttcgaaatc gaattcgtgt
    12301 tttttcaacg cttcttttac ttcagaaagc ttttctccag agtaaggagc tgcatcagga
    12361 acaacattca acgctcctcc agcttttaca gaaaactcgt tcgttcctgg tcctgtcaag
    12421 taagcttgca ataagccttt ttctgcataa attaaaggaa attcagcatc tggcgcaaat
    12481 ccttgcgtaa ttccttcttc tttttcgtta tatttttcta aacaacgcca taaattttct
    12541 tcatctgtac caaagataaa acgaatacgt gtcttgaatt ccacgccagc atcaatcaaa
    12601 gctttgacgg catacattgc cgcaatagaa ggacctttgt catcttggga tccgcgacca
    12661 actaaccagc cgtcttttat agttggatcg aatggttttg tttcccaatt attttcgtcc
    12721 cctgctggaa caacgtccat atgacacaag ataccgaata attcatctcc agagccaatc
    12781 tctgaataac cgtaatagcc ttctggatct ttaaatgttc taaatcctag cttttcactg
    12841 atttccaata ctttatccaa agcttcaatc acttttttac cgaagggatg tccttgtcct
    12901 gaatctgctt catctagtac ggaaggaatt cggatcaatt cgctcaatga ttctaatgct
    12961 tgttcatgat gttgttctgt cacaaatttt ttcatgatat tatcctccta atatgttaaa
    13021 aagggtcatg tcaaattcct ccgacacaac ctcttcttct caaataatga cgttttaagc
    13081 ctgctccatc agcaagcaga atgttcttaa caaatgatga aagaaaaaac actcactgaa
    13141 tggagctatt gacttgtcca cgtgcttatc gatagccgtt tatcggtttc ttcattctta
    13201 tgatagacct tgtacctgta tttgtctagg tttagaacat tgctgctaca cctaggatca
    13261 cacagatggc tacaaataat atcgcaatta atttaccggt aaatttccac cacactgaaa
    13321 catcgaaacg agcaattgct acagcaccca ttacgatagc agatgttggt gtaattaagt
    13381 ttactaaacc agatgcagat tgataagcag tgattactaa atccttaccg acgccggcaa
    13441 attcacccat aggtcccatg attcccattg ttgcagcagc taagccggaa gttgaaggaa
    13501 tcaagaatga catagggata tagaaaataa atgtaataat gatgaataca cttgaagata
    13561 atgaacttaa tccttgttcg ccccaatgta agatggtgtc tgtgattaat ccattgttca
    13621 taaccacttg gataccacga gcaacagcta ctacgattgc tacaccgatc aaatcagaag
    13681 caccagctaa aaattcagag acaaattcag actctttcat gccataagtg attgctacta
    13741 cgatggacat tactaagaat aacatagtaa tttctgggaa gtaccagtca cctaatggaa
    13801 gcatgctttt acctagaaca gtacctagta ccggaaggtt tgttaaccag tttgtcaatg
    13861 attcaaaaat cgtgaaattc gcattcaagg ttgtccaagg aatcaaactg atgatcatga
    13921 taccaaaagt aataaagaac aatacattaa catgtttttg ttttttcgtg attacttctt
    13981 gacgaccgat tgcttcaata tcgaaatgct tcatatcttc tttacgttgg ttgtatacta
    14041 atgattttgt tggatctttt tcgatctttg atgcataacg atacacatat acaatagaaa
    14101 tagctaacaa aataacgaac atcaagaatc gaagaccaat accttcaccc atcgaaatcc
    14161 caacagcttg tgaagctacg cctgttgcaa aaggatttac cgttgaagct agacagccta
    14221 cttgagaccc tactaatacg attgctactg ctactactgt atcaaagcct acagccatca
    14281 taactgggat cagtaaagca tagaatggaa tcgtttcttc tgccattccg taagtagagc
    14341 cgcctaatgc aaataacagc atcaatactg gaataagcat tttttctttt cctttgaatt
    14401 tcttcacaac tgaagcaatc ccggcatcta gtgcccctgt tttgttgata atacctaaaa
    14461 atccaccaac aaccaaaatg aagaaagaga ttgggattgc agcaggtgtt tctttagtta
    14521 gctcccccgc tggtacacct aacatcccat tgattggcgc catgaaaata tcccacagcc
    14581 cttgaggatt ttgttgtact cgttcatatg atccagcgac gatgttgcct gcatcgtcta
    14641 cactatagtg cccagctggt ataaaccaag taagtacagc gattactgca ataataataa
    14701 ataagaccgt atacgctgaa ggcatttgaa attttttctt ttttgtttgt tccatcttct
    14761 tcttcctttc ttttccgtta gagacaacaa ttttggctct aatgttattt tatcaaaaag
    14821 agtatcagaa caaaaataat aacacgcatt ttgtaaaact tttgttcaaa aagttcgttt
    14881 ttccctattc cctcctcttt tttcaggttt ttaaagcttt cttctttttc attgtagcgt
    14941 ttcctttttt ttataaacaa acattttcgt cttttaaaag gagaagaatt tcacatttgc
    15001 aaagaattga ttgattttta tgcataaatc aaaaaaatac tcaaaacaaa caaataaaac
    15061 gtttacatta ttgcatgtct tgtatttttt tccaaaaaaa aagaccaaga aatttcttga
    15121 tctttttgat aattatttga ctgctgtatg acgttgttcg aactgatgtt gttttcgact
    15181 taaccatgga agaagttgcg catgcagcac taaaaagaca gcgctcacga tgaatccttt
    15241 gatcaagttg aaaggaacga tcccaatcag tacatagttt gctaaagaca tgcctagcat
    15301 ctgtgttgcg ttcagtccta aaaacattaa gtaaagaggc gtaataacga aataatttgc
    15361 gatactcata aaaatagtta gagcgatggt tcctgtaatg acacctaaaa atttgtttct
    15421 tcctttatgc tgtttcttta cactaaagaa ataataaatc gggaatgtaa agatcgttgt
    15481 tgataagaaa ctagcagtgt ctcctaccaa attatccgga gaaaaacctg tagtcagcag
    15541 atgtaatact gaacgcaaga acgctgttgc aactccggcc gctggaccga ataagaacat
    15601 gctgatcaat accgggatat cactaaaatc gatcttcaaa aaactaaaag ccggcatgat
    15661 cggaaaagca aaatactgta aaactaacgc gatcgcagca aacatcgcta ctgcaaccat
    15721 tttctgtaca cgggtgttct tcatttgaaa tcctcctgtt aggactcctc ttcagcgaac
    15781 tttttgacgt ttctctccaa atgaaaaaac tctattttcc agggaaaata gagttagagt
    15841 tatttgatca agcgtcgtca aataagctct atcttcttta tccagactat actgtcggta
    15901 tcggaatttc accgattcag ctattttttg caaaataggt cgtggactat aaccaccggt
    15961 cgggaatttc accctgcccc tgaagacgaa ccttatataa tttttgttta catattcatt
    16021 atacatatct attcaaaaaa cgcaacatct aacacttata aaaagtaagt gttcattttg
    16081 agtggttcag caaactgctg acttcttttt tgttcagttc acggtaatct ccaggacgta
    16141 ggccttgtaa agtcagatct ccgtattttt cacgttttag tttttgcaca ggaagaccaa
    16201 ctgcttgaag catatttttc acttgatgat tacgtccttc gtggatcgtc aattccacga
    16261 tactgtggtt tgtcttagga tccactgata aaatttggaa tttagctgga gatgtttttc
    16321 gtccttcgat ctttattcct tttgtcaaag gtgcaagcat cgattttgta gcgatccctt
    16381 ttacctttgc aacgtaaact ttatccactt catgttttgg atgtgtcagg cgctgagcaa
    16441 aatctccatc atttgtcagt agcaagatcc ccgaagtatc gtaatccagt cgacctacag
    16501 gatagatacg ttcttttacc atcggcaaaa gatccgtaac aacttttctt cctttgtcat
    16561 ctgcaacagc agaaataact cctttaggtt tgtacaataa ataataaccg tattcttctt
    16621 gataaattgg gacttcatcc acttccacag tgtcatgttt cccaactttt atccctaatt
    16681 cccttacaac ttgtccgttt acttttacac gtcctgcaag gatgaattct tctgcttttc
    16741 gacgagaagt gatgccagcg tgggcaatta ctttctgcaa tctttccatt acaattattc
    16801 tcctttattc attccatcaa agaatagatc tggtgacacg tcttcttcaa atgaaatttc
    16861 catttcttgt gtatcaggca gttcttctaa tgatttcaaa ccaaaataat ctaagaagta
    16921 gccagttgtt ccatataata tcggccgacc tggcccttct actctacctt tttcttcaat
    16981 cagtttatgg gcagctagac gctgtaccgc tcctgaaacc tgaactcctc gaatctgctc
    17041 gatttcagct cttgtgattg gctgtttata agcgatgatt gctaaggttt cgacagcggc
    17101 ttgagataat gtgtttgatg tcccttgcgc atatcgctta agtaagggag ccagctcttt
    17161 tttagtcgtt aatacataat ggctttccgt ttcaaaaata tgcaaagctg agtgcgagtt
    17221 ttgagtgtaa gattctttta attctttcac taaacttgtg acttctgctt cgctgagatt
    17281 taacagtccg cttaattctt cattactgat cccttcctcg ccaacaataa aaagaagggc
    17341 ttcaagttca cttaatttcg tcatgttcgg tatctcctac tgctggataa agcataattg
    17401 attcatagtt ttctttttgt tgcgcaatga tctgcccttt tttcatcaat tctagcaaag
    17461 ccataaaagt agtgacaact tcacttttag aaggtgactc aaaaaaagaa tcgaaagtac
    17521 agccatgcgc atttcttttt atacgctctt cgataaatac cattcgttct tcgatcgttg
    17581 tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa tttcttacgt tctaagattt
    17641 tctgcatggc acggatcaaa tcgatttttt tgacttgtcc tcgcttcaac ggcttttcag
    17701 catccgctaa cccatcgatg ttcataggtt cttttgtgta ataaagactt cgttcctctg
    17761 ctttttctgt cagtctttca gctgcatatt tatatttacg gtattctaaa agctgagtga
    17821 ccaattcttc tcgaggatct tcttcccata attcttcatc atctgtgacg aattcttgga
    17881 caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc agccatcact aagtattctc
    17941 ctgcaacagc tagctctagt gttttcattg tatggatata attcatatat tgctccgtga
    18001 tcgtagcgat cggtatatca tatatatcga tttccatttg ctgaatcaga tgaagcagca
    18061 gatcgagagg accttcgaat acatctaatt taatattgat ctccgtcaac tcattcactc
    18121 tttcttcttt ttctttgcta gccattttcc aatgtaaggc tctgtgattt cagttgcacg
    18181 gatggagaca tccgggtact tttcctgtaa ttcatctaac atttgaaagc ccatattctc
    18241 accgcgataa gacggattca aagaaatgtc atggatgatc agctgatcgt tcgttgccca
    18301 gtaaacacca ataatccctt gaatgttggt tgaaccttct ggcgtaaaga aaaaaagttc
    18361 ataatcgtct tcagattcgt acgtatcaat ctccttcaac aaagaagttt tacctgtcag
    18421 tttcttatgg aaactcaata gtcccatagc aattttacgg ttttctttcc ggtaatgtgt
    18481 taacatcttc tcaccttcct atgactaagc ccttggaaaa tgctgcttat aaacatccgt
    18541 cattcttttc ttcgtgatat gtgtataaat ctgagtcgta gagatatccg cgtgacctaa
    18601 caattcctgt actgtccgca aatcagctcc attttctagc agatgtgtgg caaagctatg
    18661 ccgcagcgta tgtggtgtta cttctttgta aatcccagcc tctcgtacta gctgcttcag
    18721 atttttccag attccttgcc gagaaagacc tttcccatga ttattgacaa atacatgcat
    18781 ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct aagtagcgtt ccagccattg
    18841 gatcgcataa tcacctaaag gaatgatccg ctctttatct ccttttccaa ctgtctgtac
    18901 cagtccaaga gaaagatgaa gatctcccaa tttcaatcca atcaattcac tgacgcgcat
    18961 ccctgtagca tacatgactt ccaagattgc acgatctctt atccctaacg tttttgtcgt
    19021 atcaggtgct tcaatcagct tttctacttc tgtcagagtc aatgtacttg gtaatttctg
    19081 tgctttcttc ggcgtatcga tatgttgcat cggatcatga tcagtgatac gctcttgccg
    19141 taaaaactga tggaatcttc tgagacttga gatcatccga gtaacagttg ctgtcgcttt
    19201 tttttcttca tgcaacttct ccagaaaacg gatgactaaa aagcgatcga catcctgcca
    19261 tgaagcaatt ttctgctcct gtagaaaatg caagtactgt tccaaatcac gttcatagct
    19321 ttgtcgtgta ttggcggaca atccccgttc aatattcaag tagtggagat aatcgttgat
    19381 ttgctctttc ataataatcc ccctcatgcc tctctatcat atcagatacc gcttcattct
    19441 gatagtcttt ttccataatc tgagcaaaga aaaagccgtc tagacactca gacggactgg
    19501 tttctttttt ctttttcata gcattcctga cagattccat ggaacgttag ccgatgatct
    19561 tttactaaaa aatgataacg ttcttctact acttgctcca cttcaagtaa aagatcctct
    19621 tctacttcct cgatcgtgcc gcagttcaag catagtaaat gatgatggaa atgtttggcg
    19681 ccttcttttc tcaaatcata acgggctaat ccatcattaa aacttacttt atcgacaatt
    19741 ttcaattctg tcaagatttc aagggttcga taaacagtag caagtccaat ttccggactc
    19801 ttttttttca ctaaaaagaa gatttcttct gcagataaat gctctttctc attttccaaa
    19861 agcacaagca gagtagcttc tctttgcggt gtcagcttaa accccgcttc atgtagctgc
    19921 tgttttgttt ttttcatcgc cgaaatagca ttcatgacca tttactcaac cccaacaatt
    19981 tataataatt acaaataaaa aaagatataa cactatgtta attaaaatta ttttaagcta
    20041 gttaagaaaa acatgcaagg gattctcaat tagatttttt gactagtttt gtcacaccgt
    20101 tttcttgtgt aatcaatcct tgtttcaaaa gattacctaa tgcgcgctta aatgctcctt
    20161 tgctgatacc aaaagctttc atgatttctt ctggatccga tttatctgta aagttgattt
    20221 gctgatctgc agaacgttct aaaatggtta aaatcatttg tgcatcatct gatatagctt
    20281 catatgctct tggcttcaat gaaagattca gtacaccgtc tggtcggaca ccaatcactc
    20341 gaccttttat ttgctcgcct agacgaggtt cattatatcg ttcagaagga tggataaacc
    20401 caagatagaa atcttccgtt aaaacgtacg tacctgttaa tttcaagcgg tatgctgttc
    20461 ctatcacatc tttgtttttc atttcttctg ttccatattt gcttaaagat ttgaatattt
    20521 tttcatctgc taaactgccc caaatacggt cttttgcatc aactctaagg gaaatcatca
    20581 agcgatcccc ttttttaggc catagctctg tcattgtcgg caattcatca agagatacga
    20641 caaagtcttt atctggaaga ccgatatcga caaacgcacc taaatctttt cgtgtagcag
    20701 taacgattcc aaaagcgtaa tgaccgatac ggcttttagg aatttgtgta gtgatccgat
    20761 tttcatgttt ttgattttgg tagccgaatc cttccactgc ttcaccgatt ttgtgttcac
    20821 cttctgattt gcttaagcca aaggtttgtc cgtttttttg gacaaagtag tttttttcat
    20881 tttcatcaat aataatacct gtaaatatag ttgctaataa atcgttcatt tttttctccc
    20941 tctatagtga aaggttttct taatacattt ctttgctatc ataacataat gttatctact
    21001 tgaatagctg agccttggtt tggaaaggtg aaaaaaggag tatgacaaca gttgtgtcat
    21061 actccccttt ttcgaataaa cggtgttaaa cggcaggctc acagcctctt tcatttgcct
    21121 aaaattaatt gctcccattt cctccgaacc atccagtttt acagttgatg gttacgatgt
    21181 aaaatggcaa agcactttct ccaatgcctt tcatcaatgc agattttgtt gaagtggcat
    21241 atagattgta atagccttcc ccattttcga ttctggcttt ttctaatctg tatcctcctt
    21301 caacgatata tccacgttgg atacatgtag caatcacttt gctttggaca cctggtgccc
    21361 acgtccatgc tggattagat gcatcggcaa tatcacttgc tctggcagat ttgattggct
    21421 gattcgctga gtttgaagag gaaggggtcg aggatgccgc ttcttgctgt gctgcttgtg
    21481 cgaccgcagc ttgttgagcg gcttgagctg cagctgctgc ttgagcggct tgttttgctt
    21541 gttcttcagc tgcttttttc gctttttctg cttttttcgc ttcttctgct tttttctttt
    21601 cctcttcttc ttttttctct ttatcagtga gcatcttatc tacttgttgc aattgttcat
    21661 tcaactgagc agatagatct gtatttttca ctttttctac tgcttctttt gccgtcttgt
    21721 attggtcgcg tgttgctgaa tccactactt ttccgtcttt aaagactata gctgtttttt
    21781 ctttagctgt ttgcaattca gcatattgat ttttagcttc tgtttgtgct tgttgaatca
    21841 attttccaaa atctgtgtta tccgtttcga ttgcttggat ctctttatct gctttcaact
    21901 tgatgtcatc tgctagatga tcatcgacga tggcaggtgc tatgaaccac tcattcactt
    21961 tttggatatc tcggatctta gattggatat cttggtaagt tgtttctaac tctgaatatc
    22021 ctttttcatt cttaagactg gataaatcat tttttagttt tgataaatct tgatgaatca
    22081 tatctgcacg aataaattga tggtgatcat ctgtataaaa ggcagcaagt ttctcatgaa
    22141 gttcttccat ttgttgctgt ctttttgctt ctgctgctac ttcggcttct actttttgat
    22201 gatggtcata ataagcccag cctcccccac ctagtagaag aactgctgct aaagcgagat
    22261 acggcacttt ttttgatttt ttcttttgtg tcttatctaa atcttttttt tctgggtttg
    22321 attcttgagg cgttttttca gtatttggca cgattgttat tggttctgtt tctgcttcaa
    22381 tcagctcagg ctggttctct tctttttcta ttttagcttc aagagcagtg ctatcttcac
    22441 ttgcagattg agtttcagca tcggcttcat tatttattcc atccgactct gttgccttct
    22501 tgtctgcttt ttcgagcatt tcttttttat ctgcttccgg caacccattc gatttctcgt
    22561 cttctgattg tttttcagac aatgtttcag ttttttccgg gatatccgtt tttagatcat
    22621 tcgtttttag atcattcgtt tttaatgatt ctttacctgc agcgtttact ccactaatgt
    22681 ctttttcagt gtctttttca gcttcatgtt ctggctctac tttgttttcc tgtgcaattt
    22741 tttcactgat cattttgagc agctctttcg cgtgctcttc ttttgtatct tcacgatgtg
    22801 ctttgatata agcggatagt atcgaatttt cttcctcatt atcgacgatt tctttcagtt
    22861 cagctactct tcttttttgt tttgattcaa gcgtttcttc ttgattcttt cctgattctt
    22921 ccgaagtctc atgaacagtt gctttcttct gttcattttt ctctatatta gttacttgat
    22981 cgtgagcagg tggttcttcg tcttctggtt ctgctttttc gaataattcc attacagatt
    23041 ctagaggtaa atctttcaat tccgaccatt cgattggatc gtttaattct gtatcaggaa
    23101 agactgcatc ttcagttgat ttatcctgca tagctgcatc tgtatttgtt tcttcaattg
    23161 attcttttat ttgctgatct tctgcagtta tttgatgacc gcagtctgga cagatagtat
    23221 tctgctccat ttttttcgat ccgcaatttg gacatttttt catcacttag cgatcggctc
    23281 ctttactagg tttacgctac catttaatct atcatattct atacgtcacg ccaatagctt
    23341 atttttagga tttacttaaa aataatgaat gaatttcctt cctatagaaa aaaaagcttg
    23401 agactgcgta gtctcaagct ttttttcttt taaaataaac caaacagttt tactgatttc
    23461 tcttctggtc aatagttcat gcttattcta agaaatcttt taattgtttt gaacgagaag
    23521 gatggcgcaa ttttcttaat gctttagcct cgatctgacg aatacgttcc cgagtaacac
    23581 caaatacttt ccctacttct tccaatgttc tcgtccggcc atcatctaaa ccaaaacgta
    23641 agcgaaggac attttcctcc cggtcagtca atgtatctag tacatcttcc aattgttctt
    23701 ttagtaactc ataagctgcg tgttctgctg gacttgttgc ttcctgatct tctatgaaat
    23761 cacctaagtg agagtcatct tcttcaccga ttggcgtttc aagtgaaaca ggttcttgcg
    23821 cgattttcaa gatttctcgg actttttctg ttggaagatc catttccgca ccgatttctt
    23881 ctggcgtagg ttctcttcca aggtcttgca gcaattgacg ttggatacgt atcaatttat
    23941 taattgtttc aaccatatga actggaatac ggatcgtacg tgcttggtca gcgattgctc
    24001 gagtgatggc ttgacgaatc caccatgtag cataggttga aaacttaaat cctttgcggt
    24061 agtcaaattt ttcaactgcc ttcatcagtc ccatgtttcc ttcttggatc aagtcaagga
    24121 actgcatgcc tcgtcctaca taacgtttag cgatacttac tactaaacga aggtttgctt
    24181 ctgccagacg ctgtttcgct tcttggtcgc cttcttcgat tttcaatgct aacgctactt
    24241 cttcttccgc agttaaaagg gagacacggc caatttcttt cagatacata cgaaccgggt
    24301 cattgatttt tacaccggtt ggcgcagata gatcttctgt ttttgcttgt tcagcttttt
    24361 tctcagcact cttcaagctg tgaattgatg gatcaccatt ttcatccacc acactgatac
    24421 ctgcgtcttc aatcttttgg atcaatttgt ccatttcatc tgcattcaaa gtgaatggtg
    24481 tagcaagctg attggataaa tcatcatata caacttgtcg tttgggtttg ttttctttga
    24541 tgaaagctgc tactgctgct tcatacgttt ttttatctgt tccatttgcc ataaaagaag
    24601 gccccccttg agtagctatt tggcttgttt taactgtttc gttaaattga tgatttcaat
    24661 cgtcaattca agctcaagct gtttgtttcc agttcgtctg gcttcttgct gcatttgttt
    24721 ttttaatgtt atttcatcag ctaagccaga tttgctgatc acatctagca agtcttggat
    24781 ttctcgtggc gaactttctt ctgccaccgg taaatattcg atttccacca ccaaccgcct
    24841 taaattttca tcttgcaaaa agtctaaaaa ctctgcaagg ttgaattcat aatgttgtga
    24901 gacatatgca tcgaataaaa aataaacttc tgcatatgca tcatgaataa actgaaattc
    24961 tcgttctttt aaaatattac ggacagaaac ttctttaaat gcacgatata atagaatctg
    25021 ctctgccttt tctacttgcg tcaaaggtct ctttttccgt gcagtttctt gtctcgtaac
    25081 ctgagtgtgt tgactttcct gaggttcttg acgattttgc tgatttgtcc ttcgaagatc
    25141 gcgcagttgt ttttgtatcg tctctctgcc gatctgaaac tctgttgaca gttgagatag
    25201 atacatatct tgttcgattg gtgaaacaac tcggctaagt tcaactagta attcttcgag
    25261 gtattcgatc ttgtcttttt cattatctaa atttttccct tgttttaaat aacgtgattt
    25321 aaaagtaaag actgtttcgc gcccatgagc cactaattct tggaaagatg cttctccata
    25381 cttacggaga tattcatcag gatcaagctt ttctggaacg actacgacag aaagtgctaa
    25441 gcgactgttt tgccgaagca attcaatccc tcgattggtt gcttcaaaac ctgcgttgtc
    25501 tccgtcatag caaaagacca attctttcgt cagcttttcc atttgttgga tctgttgagc
    25561 tgttagactt gtccccatag aagctaatcc agttttgata ccagcctgcc atgcagcaat
    25621 cacatccata aacccttcga acaacaaaat ttctccgttt ttccggatat cgcttcttgc
    25681 tttatcaaga ttaaataaaa cttgtctttt attgaacagt tctgtttctg gactattcaa
    25741 gtatttgggc tgatcttttt cctgcccttt ttcaggtgca agccagcgtc ctgaaaaacc
    25801 gatcgtctgg ccttgagaat tacgaagtgg aaacatcact ctttgataaa aacgatcaga
    25861 catacggcca tcatcatgcg tgacaaacaa tccagagcgt tctaacaatt catttgaaat
    25921 tgattcattc ttgaatactt gctgaagaaa agaacgctca ttaggtgcaa aacctatgtt
    25981 gaattcttca attaattcta aagacaaccc acgactttgc aaatattcta aagctggctg
    26041 tccagctttt gtatgcaata gcatgtgatg atagatttcc gctgcttttt catgagcagc
    26101 aatcagtttc cccgtagcag attcaggatt ttggacagct atagtacgct gacgccattg
    26161 atcttctaac ggtatctgtt cgaagtctgc cacttttacc actgcttctg gaaaacttag
    26221 accttctagt tcttgaagaa aagtaaacac gtttccgccc ttaccacaac caaagcaatg
    26281 aaaaatctgc ttgtcttctg caacagaaaa agacggtgta cgttcttcat gaaaaggaca
    26341 cagccccaag taatttttac cagacttttt caactggaca tattgtccaa tcacctcaac
    26401 gatattcgtt tgactgcgta ctgtttcgat aacctcttga ggaatccgtt gagccatttt
    26461 tccaccccct gctctattga tatcttttgg gtttaacaga agatatttca ggagaataac
    26521 cggtaaaaaa tcgcactaac tgaaatcagt gcgattttaa aggacacaat tatacatgtt
    26581 tgattgtatc atatttcatt gctttttcaa gtataacaca tttctatctc attaagcatc
    26641 aatttgctac tcttttcagt aactgatttt gaatatcagc cttccagtac aatactcgaa
    26701 gaacaatatt tacgagcatg aatacaaaga agtatcctac gctctctccc aaccctaagt
    26761 ttacttccaa aattccatgg aacagcattg cagctacata tatccctacg atcgtcgtta
    26821 ctgctaggaa gatgcgcaat gggttgaagg gataacaagc ttttacaact gccatgcaac
    26881 tgatcccaat cagcaagtaa tacatcaaag tagtagtttc agcatttccc catgcgaatg
    26941 tttttccaag tagatacacc gcaatgatat tcactactac aagcaaggca tttggtaaag
    27001 cattaataag tgctgtaggc aaataacggt aagtgatttt tcttttatct tgttcaaaag
    27061 ataaaaagaa ggaaggatac ccttcaatcg ctaaatcaat cagcgtgatt tggataggga
    27121 taaacggaaa tccaattgct gtaacggcac atataatcga taaaataaat gaataaatcg
    27181 ttttgataaa aaagatgcct gagactttcg tcacattgtt gaccactcgg cgtccttcaa
    27241 acaggacttc tggcaatgta gtaaaatcag agtccaacaa taccagattc gcaatctgac
    27301 gtgttgctcc atcaccttct gccatagcaa tgctacaatc tgcttctctt aacgccaaaa
    27361 catcattcac accgtcgcct gtcattgcaa ccgttctgcc gctttctttc aattcattta
    27421 ccagcaattt cttttgctga ggactcactc gtccaaaaac cgtatagcga tgagcagctt
    27481 ctcgcacttc catttcttca gtaatttgag aaagatcgac atacgcatca taattcggta
    27541 atcctgcacg tctagcgata ttggagacag taaaaggatt gtctccagaa atcactttca
    27601 gatccacacc ttcctcatga agataagcta gtgtttcttg agcgtttttt cggattggat
    27661 catcgatttc aaacagagca accggctcaa caaatgctgg tttttcttcg ttcaattgct
    27721 gatttggagc gatccctaac ataagtacgc gatagccatt cgcttgggct gtttttagac
    27781 tgtccggaag ccgatcttct tccaccaaac gttcaggcgc tcctacgtac acgactccca
    27841 gttctggaaa ttccatcgcg ccccatttgc gatcagaaga aaatgcgact ttgtttgtca
    27901 catcataccg attagaaagc tcaaaataat ctctcatagc ccgcatagtg atgttgttat
    27961 cactgctttc tgccagatac gtccccataa tttctgggat ggctttctcg tacagcggat
    28021 gtagtgcttc tacccgctgg atactcattt ttccttcagt aatggtccct gttttatcca
    28081 agcataatgt atcgacatgg gccagcgttt caattgaata catgtcttga acaaggattc
    28141 gtttttttgc cagtttggtt acccctgtcg ttaatgcaat acttattagc aataccaaac
    28201 cctttggaag catgcctaac aaagctgctg cagatgcaat aacagaaatt ttgatagaag
    28261 catcgcggat gaacagtgct tccaaaaata gtatgatccc caaaggaata atcacgaaac
    28321 tagtgaattt ggatactttg cgaatcgaat ctacaagttc agaacgaata gctttgtgag
    28381 tctttgcctc gctagtcaag cggacagcat aattatctgc acctactcgg ataacttcag
    28441 ccatgacaga accgcttgtc aaaaagcttc cagaaagcaa ttcagctcca gtttctttga
    28501 caatcaaatc agattcgcct gtcaaaagag cttcatttgc ttctgcccgt ccagatataa
    28561 cctgtaaatc ggctggtatc tgttctcctg ctccgatttt taccaaatct cctaatacca
    28621 gctctttagt agaaatcgat tgttctttac cgtcccggat cactagtact tctgattggg
    28681 aaacaatcga taatttccgt acaagatttc ttgcatgtat ttcttgataa attccaataa
    28741 cgatattgac gacaataatt gctaaatacg ccatgttgga atacgcacct acaaataaca
    28801 gacaaatccc aataccaaag ttcagaaaat tgaataacgt caatatatta tcgctgaata
    28861 tttgttttgt actttttgat gcatcttcct ggtagtcatt ttgctggcca gaagccattt
    28921 tctgaactac ctcttgctgt gtaagtccat tcattttctt tttctccatt ttccgccaac
    28981 tttcaaaaat aatcacgtgt ttaagtctag cgtgttccaa gattaaaaac aacttgtttt
    29041 tataaaattt atagaaaaac acacgaatga ttttacaaaa aagatgccaa cctttttgtt
    29101 tgaatcaccc gtgtgctgtt tttattatca atctatcttt acttatattg ttcctccaaa
    29161 cggctcatcc accaacctag tgctgtaccg gctataaaaa gaacaggaca agctagtacc
    29221 ccagcaactc ccaatcccgc gtaatcggta ggaatgatca taatcgttga agcaaaaact
    29281 acacctaaaa tgaaatggaa tagcttgcta tatgcctttg agaaaatgta atccatgatt
    29341 tttgacaatc caagaacaca aagaatccca ccaattccga tcggcacaat cacttcaagt
    29401 cgtacttctt taaatccgtc agccatcgct ttatacaatc ccatatacac caaaaaatta
    29461 gaagggctca atcctgggac gatcataccc aaaccaatca atccgccggc aatcagccat
    29521 gttccaaaat tctgatcgac ttgcccgtca aataattgag cgccgtataa taaaaacaaa
    29581 taagccagaa caaaagtaac aaccatgatg atcacatcag aagtatctct tccttttttc
    29641 cctgcttctt tccataacgc aggaacagtt ccagcgatac atccgacaaa aaaccataat
    29701 atcgttgttt catacgcacc taataaaaaa ctgactaaaa aagaaagtag aaagatgcct
    29761 gtcactccgc ctagaccaac aggcagaaaa aacaaaacat tttctttgaa attttttgta
    29821 aggtgggcta aaaaagaaat cagccgctca tacatgccaa agacagctgc taatgcacca
    29881 ccgctgactc ctggcaagat aaatcctgaa ccgataaaca ttcccttcac aaaccgtaac
    29941 atccagtctt tggttgtgta ccccactttt tgattttcca ttttttgcct tttttccact
    30001 atttgcgcac tccttctttc atttaatttt attcatgatt gaacatttcc tgctatttta
    30061 cttaaaaact ttttcatagg tctctattat tttttcattc attttgacaa tatcaggata
    30121 aaacatgtta cctccattat gatagagata gccgccattg taaagcaagg actggatccg
    30181 ccaatatcgg tattgtttcc cttcctcatt tcctaaaagt gggctcagca catctttaga
    30241 atacgcttct gctaattcta ctgtgttttc tccgccatga ttttttacat aggcaatata
    30301 atctttccca aaattatatg cttggacagc tgtccataaa tcgcatcctt gtttctttgc
    30361 ttctactatc atttccgcca aatatttgac accttgatca atactgtcag ctggattatc
    30421 aatgatctca gcttctccat gcagactttc cgagctccgc atgagatctg tcccttttcc
    30481 ttttgattcg gtcaatatta tcgccttgat caaattctcg tagttttcca tatgataatt
    30541 ttttgcagct gttgttattt ctatttgata gctttccact cgttttaccg aacgataagt
    30601 tcttcctcct aaaaacaaca ccgcaccaat aaccgtcaga atgatcatgt aaaaaagaat
    30661 acggataata gataatcgtt ttcgcttcat ttcatcacct agttattttg acatcttttt
    30721 ttatcttact atttctttat cttcttggct atttcttcct tgatttctgt gtacgcctta
    30781 agaaaaaatg aattttcctg tattttttgt catcttacga aaatgatcgt tgtttttcag
    30841 taaaaacaat tgcccaatga ctgatataat cgttatactt tacacagtag gtgattatgt
    30901 gaaaaaagaa aagaaatatg caaaaatgcc agatgggagc gaaatttact atgaaaagag
    30961 cggtcaaggc ttccctctct ttttactgca tggcaatgac ggcagcggcc gctttttttc
    31021 agaacaggtc cctgtactcg aacgctacta taccgtgtat ctagtagata gccgaggaca
    31081 tggtcgttcg acaaacgaag catctatgtt gaattttcag ttaatggccg aggatctgaa
    31141 tacgatcatg ttgctggaaa aaatcgatca ggcagatttt cttggattta gtgatggagc
    31201 aaatctagca ctggtatttg ccagcagctt ccctaaaaaa gttcatcgat tgattttaaa
    31261 ttctggaaac acgcttgtta aaggcgttcg tttttctgcc agagtcatca gtaatattca
    31321 ttatgcatgg gtatggttac tctctttatt tcgcccaagt cttcgcaaaa atcttttagt
    31381 tatcaaactt ttgctgcatg acatcgggct tacagaaaat gatttaaaaa aaatcaactc
    31441 ccccactttg atcatcgtgg gaaaaaaaga tgtaatcaag ctaaaacatt ctttgtatat
    31501 agctaaaact ataccaaaag cttcctttgt gcttgtgaaa gaacaaggac atgaattagc
    31561 tagaaaagat cctgaacgct tcaatcgaga agttcttcaa tttctttctg aaacataact
    31621 attaggaata gaaggtgatt tatttgttaa aaaataccat acaatggctg aaaaaccacc
    31681 taggactgtt caaaacaatc tttttgattt ctgtcattgt cattattgtc ggtgaattga
    31741 tgtccatcgg taaaactcta tctatccagc aattaggaga aacgtttgcc actatacctg
    31801 tatggaaaag cggacttatg ctgttgattg gtcttgtctc tgtgttacct atgattggtt
    31861 atgatattat tttgaatcgg atgcttgaac aaaagcagaa tcctcgttac ttgtttgaga
    31921 caagctggct gatcaataca atcaacaata ttgccggttt cggcgggttt gttagtgtgg
    31981 ggcttcgctc tgaactatat ggacaaaaga aagagagcag aaacgtgatc caagcattat
    32041 cgaaagtttt cttgtttttg atggctggac tttctattta cagtctgctt tcttttttac
    32101 ttgtagtctt cacgccagtt gctccttttt tgaagcaata ttggatatgg ttgatcggcg
    32161 gcggtctata ttttcctgtc gtctttttat ttactacttt caaaaagaaa ggattccttg
    32221 gtggtacctc acttaaaact caaggacagc tattgctagt ttcattgttg gaatggaccg
    32281 gtgtcctgtt tagtttcctt tctgttggtt atttaatgga aatccggatt gatctgtggc
    32341 aaacaattcc gttattcatt gctgcttcag tgataggaat cgtgtctatg attccaggag
    32401 aaattgggag tttcgatgta atgatgatta tcgggttgtc cgctattggt gtgccaagag
    32461 aaatagtcgt tgtgtggatc ttgctctatc gcctgttcta ctacatcatt ccgtttttga
    32521 ttggaatcgt ctttttcttc aaaaatatcg gttccacttt tgatcagcgt tattctggta
    32581 tccctaaaca attagcaaca gaaattgcgc ataaaatcgt ggttgtctta ttatactttt
    32641 ctggaatcat gctagtactt tctgccacta tcccgcaagc ttttacagag tttcgctggc
    32701 ttcatagttt gaacccattg aaatttcatt ttattatcca atttcctagt atactattgg
    32761 gatttctttt aatcattatg ggcagaggga tcgcagcacg tgtgaaacga gcatatttgc
    32821 ctacaatctt cttgattgtt ctagctttac tttatgtttt attaagtgat tttagtttca
    32881 caccggtggt tttcttgtct attctgcttc tgatcattct tgcttctaaa aacgaattat
    32941 ttcgggaaca attgatctat tcatgggagt ggcgtacgat cgatggaatc attattggtg
    33001 cactgtcctt gctttacatc gttattgggg tatacaatct gccggatttc cctcatcggc
    33061 gtcaccattt tatttccttt ttcttatttc cttctgaaaa gatttggttt tcgggattgt
    33121 tggccatcat cgctgttagt ttcatgatcg ttctatttgt tcatttcctt caaggagaaa
    33181 agaaacagat tggcgaagcc tttaatgaag aaaaggccct gaagatcctt acaacttatg
    33241 gaggaaactc cgatagtcaa ttgatcttct taaaagataa gcggatgttt gcctatgaaa
    33301 aagacggtga accaactgtt cttctccaat tcgcttgctt caataataaa tgtattgtaa
    33361 tgggtgatcc ttctggtaag aaagaagatt ttccagaagc aatcgaagct tttatcgaag
    33421 aaacagatcg actatgctat ttaccagttt tctacgaaac aagcgaagag attgttatga
    33481 ttttgcatga attcggctac gatttcatta agatggggga agaagcttat gtagacctga
    33541 atagttttac aacttcaggg aaaaaaatga agggcactcg tgctgtcttg aatcggatcg
    33601 aacgagaagg atttacattt gatgtcttac aaccaccatt ttctactgag caaatgagta
    33661 ctttcaaaaa tatctctgat aattggttgg gttcacgaaa ggaaaaaggg ttttctttag
    33721 gctttttctc tgaagattat ctacaaagag cgcctattgc agttgtcaaa aatacccaag
    33781 aagaaattgt cgcttttgca acgatcatgc ctacttacac gaacaataaa gtaggaacga
    33841 ttgatctgat gcgatatgat cctaaaaaag caccttctgg cagtatggat ttcttgttct
    33901 tgcatttgtt tgcctatatg aaagaagaac atatccaatg gttcaattta gggatggccc
    33961 ctctttcaaa tgtcggaact tccagaaaga gttttttaca ggaaaggatt gcatacttgg
    34021 tttacgagtt tggttctcat ttttattctt tccatggatt aagagaatat aaaagcaagt
    34081 acgctacaaa ctgggtctca cgttatactc tatattctag agatagttgg attgcatatg
    34141 ttatgattgc tttgctgatt attgataatg cgccagttga gcagacacaa ggtagaataa
    34201 gtggtttgaa aaaatggata cgaagaaagt attaaaaact gcataccgat agatgaacac
    34261 tctcatgatg aataaaagag actgaagtaa aacgaaagtt catgcttcta caatctcttc
    34321 ttatacaatt gaagaacaaa gagcggtcca aacagaaatc ctgtttggac cgctctttta
    34381 ttttaaacat ttttcattac caaaatattc gagtcgcgtt tcttatgctt cgatctctgt
    34441 aacgatacct gaacccactg tccgtccgcc ttcacgaatt gagaatgtcg ttccgttttc
    34501 aacagcgatt ggatggatca agtcaacatc aatcgtcacg ttgtcaccag gcatgaccat
    34561 ttctgtatct tctggcaatg tgattgttcc tgtaacatca gttgtgcgga agtagaattg
    34621 tggacgatag ttgttgaaga atggagtatg acgtccacct tcttcttttg tcaacacgta
    34681 cacttctgct ttgaattttg tatgtggagt aatggaacct ggtttagcaa gcacttgtcc
    34741 acgttcgata tcgtcacgtt ggatcccccg taacaacacg cctacgttat ccccagcttc
    34801 cccgtaatct aacgttttac ggaacatttc tacacctgtt acaactgctt tttgtgtttc
    34861 aggtttgatc cctacgatct ctacctcatc accgacacga acagcaccac gatcaatacg
    34921 acctgaggca acagttcctc gacctgtaat tgagaagacg tcttccactg gcaatagtaa
    34981 tggtttatct gtatcacgtt ctggtgttgg gatatattca tctactgtat ccatcaattc
    35041 cataatagca gcttcagcat ctggatcgcc ttgcaatgct tttaatgcgg aacctttgat
    35101 cacaggagtg tcatcgcctg ggaaaccata ttcgctcaat aactcgcgaa cttccatttc
    35161 taccaaatcg atcaattctt catcatcgac taaatcaact ttgttcaaga aaacaatcag
    35221 gtattttaca ccaacttggc gtgacaataa aatgtgttca cgtgtttgag gcatcggacc
    35281 gtcagttgca gaaacaacta agattgcacc atccatttgt gctgcccctg taatcatgtt
    35341 tttcacatag tccgcgtgtc ctggtgcatc aatatgcgcg tagtggcgtt tttctgtttc
    35401 atattctacg tgtgcggtat tgatcgtaat cccacgttca cgttcttctg gagctgcatc
    35461 aatactagca tagtcttgag gatttgctag gccttttttg cctaatactg tagtgatcgc
    35521 agcagttaaa gtagttttcc catggtcaac gtgtccaatc gtaccaatgt taacgtgtgg
    35581 tttacttctg tcataatgtt cttttgccat aatttacaaa cctcctaaat aatatagatc
    35641 actgaaaaat ttcagctctc acctttttat tatagtcttt ttttgactaa atcaaaaaga
    35701 atacgtccga cttacttttt gtaagattcg aactaagctt attatacgtc aatattggtc
    35761 aaagtcaact aagagcactc gcttgtctta tacgcgaaaa aagtaccttt tataaataaa
    35821 aaaatgtgtt ttttgagaaa aacttcaaga tagtccttaa ctttcttttg aagcaataag
    35881 aacaaaatga ggaaaagttt aaaattcagc tgttgccaac aactttcaat agacgaaatc
    35941 ttctatttcg ttaataataa ggaaagaggt gaagtacatg aaaaaattaa ttggcgtact
    36001 tgtcgtttta ggcatatttc tcggcggaag ttttgcagct tatcattatt tttacggcgg
    36061 cgaagcttat tatacaaaaa tcacgacgaa tggcgaaatg tcagctaccc aagcagataa
    36121 cggagagaaa ttcacgactt atacctacaa gcaagcggct tataataaag atggtgaaaa
    36181 aaaacaggtg acgcttcgcg aagaaagaga acatccatta aagatgaatg cgtatcttaa
    36241 actcaaagtc aatcctcgta aaggtgtatt aagctgggaa gaaataaagg cttctgaagt
    36301 gcctaaaaat gcggcagaaa aaatcgataa ttagtaaatg gtcttaaaat ttta
//
LOCUS       DAFKHN010000022        35953 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFKHN010000022 DAFKHN010000000
VERSION     DAFKHN010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.022"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            23..694
                     /locus_tag="LY912_001095"
     CDS             23..694
                     /locus_tag="LY912_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBM6954805.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            753..1193
                     /locus_tag="LY912_001096"
     CDS             753..1193
                     /locus_tag="LY912_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954806.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1205..1873
                     /locus_tag="LY912_001097"
     CDS             1205..1873
                     /locus_tag="LY912_001097"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBM6954807.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1937..2560
                     /locus_tag="LY912_001098"
     CDS             1937..2560
                     /locus_tag="LY912_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBM6954808.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2616..3002
                     /locus_tag="LY912_001099"
     CDS             2616..3002
                     /locus_tag="LY912_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBM6954809.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3215..4606
                     /locus_tag="LY912_001100"
     CDS             3215..4606
                     /locus_tag="LY912_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBM6954810.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5217..5585
                     /locus_tag="LY912_001101"
     CDS             5217..5585
                     /locus_tag="LY912_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBM6954811.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5765..6706
                     /locus_tag="LY912_001102"
     CDS             5765..6706
                     /locus_tag="LY912_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBM6954812.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6775..7506
                     /locus_tag="LY912_001103"
     CDS             6775..7506
                     /locus_tag="LY912_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBM6954813.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7650..9830
                     /locus_tag="LY912_001104"
     CDS             7650..9830
                     /locus_tag="LY912_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBM6954814.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9850..10332
                     /locus_tag="LY912_001105"
     CDS             9850..10332
                     /locus_tag="LY912_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBM6954815.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10348..11109
                     /locus_tag="LY912_001106"
     CDS             10348..11109
                     /locus_tag="LY912_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBM6954816.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11240..12574
                     /locus_tag="LY912_001107"
     CDS             11240..12574
                     /locus_tag="LY912_001107"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBM6954817.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12881..13366
                     /locus_tag="LY912_001108"
     CDS             12881..13366
                     /locus_tag="LY912_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBM6954818.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13359..14042
                     /locus_tag="LY912_001109"
     CDS             13359..14042
                     /locus_tag="LY912_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBM6954819.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14168..16813
                     /gene="polA"
                     /locus_tag="LY912_001110"
     CDS             14168..16813
                     /gene="polA"
                     /locus_tag="LY912_001110"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBM6954820.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16858..17694
                     /gene="mutM"
                     /locus_tag="LY912_001111"
     CDS             16858..17694
                     /gene="mutM"
                     /locus_tag="LY912_001111"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBM6954821.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17658..18287
                     /locus_tag="LY912_001112"
     CDS             17658..18287
                     /locus_tag="LY912_001112"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBM6954822.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            18339..18671
                     /locus_tag="LY912_001113"
     CDS             18339..18671
                     /locus_tag="LY912_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBM6954823.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18983..19474
                     /gene="nrdR"
                     /locus_tag="LY912_001114"
     CDS             18983..19474
                     /gene="nrdR"
                     /locus_tag="LY912_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBM6954824.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19497..20870
                     /locus_tag="LY912_001115"
     CDS             19497..20870
                     /locus_tag="LY912_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBM6954825.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20870..21796
                     /gene="dnaI"
                     /locus_tag="LY912_001116"
     CDS             20870..21796
                     /gene="dnaI"
                     /locus_tag="LY912_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBM6954826.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21925..22365
                     /locus_tag="LY912_001117"
     CDS             21925..22365
                     /locus_tag="LY912_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBM6954827.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22509..23210
                     /locus_tag="LY912_001118"
     CDS             22509..23210
                     /locus_tag="LY912_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBM6954828.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23207..24328
                     /locus_tag="LY912_001119"
     CDS             23207..24328
                     /locus_tag="LY912_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBM6954829.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24343..25575
                     /gene="pepT"
                     /locus_tag="LY912_001120"
     CDS             24343..25575
                     /gene="pepT"
                     /locus_tag="LY912_001120"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBM6954830.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25707..26615
                     /locus_tag="LY912_001121"
     CDS             25707..26615
                     /locus_tag="LY912_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBM6954831.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26650..26922
                     /locus_tag="LY912_001122"
     CDS             26650..26922
                     /locus_tag="LY912_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBM6954832.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26933..27979
                     /locus_tag="LY912_001123"
     CDS             26933..27979
                     /locus_tag="LY912_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBM6954833.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28230..30839
                     /gene="clpB"
                     /locus_tag="LY912_001124"
     CDS             28230..30839
                     /gene="clpB"
                     /locus_tag="LY912_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBM6954834.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30990..31676)
                     /locus_tag="LY912_001125"
     CDS             complement(30990..31676)
                     /locus_tag="LY912_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954835.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31654..32148)
                     /locus_tag="LY912_001126"
     CDS             complement(31654..32148)
                     /locus_tag="LY912_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBM6954836.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32168..33388)
                     /locus_tag="LY912_001127"
     CDS             complement(32168..33388)
                     /locus_tag="LY912_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6954837.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33535..35370
                     /gene="lepA"
                     /locus_tag="LY912_001128"
     CDS             33535..35370
                     /gene="lepA"
                     /locus_tag="LY912_001128"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBM6954838.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            35566..>35953
                     /locus_tag="LY912_001129"
     CDS             35566..>35953
                     /locus_tag="LY912_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6954839.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEK"
BASE COUNT        12086 a         6301 c         7705 g         9861 t
ORIGIN      
        1 tgatgaaaaa agggggagaa aaatgaattt tttagttgtt ttaaaagata ctctgattga
       61 gcgatctaca tttctatatg ttcaattgca ggaaaataaa acattgctgc atttttcacc
      121 agagttccat ctagaggggc taacattagg agaaatctat caagcagaag ggctgtcggc
      181 tgttttgcac ttttttaagg tagaattgga attaccagta aaagattata tcgagctttc
      241 tcttgaatct tgggatcgag cagtggttga actgtttcca gaaggtttaa tgatcgatac
      301 aaacgatggg aagatccatc tgactgcagc agaactgcaa aaacaaatgc gttatcaaat
      361 agatgacgaa aattcttttt ctatttttag acgtcagcaa aagattctaa aaagcttttt
      421 aaaagtgatc agtaaaaaac ggaatctgat caaaacgaca cagctgttga aaaaatatcc
      481 aggtctgctt cacacgtcta ttcaatttcc tcaattgatt acgatgatcc atcgttttat
      541 acgtatgcaa cagctaccat ctaagaagct gtttcttcca ttgacggaca catttcgagt
      601 agtcaacaga gaagataaaa agaaagtgat tgtgattgac tttaccagaa atcggaatgt
      661 ccttcaccaa gttgcaatgg aaaaggccaa ttaaggcttt ttctttttgg atttttttgt
      721 cataataaat attagatgat ggaggagata atatgatgca aacatggtta gaaaggctaa
      781 tacgatttca gcagaactat cacaaactta tgcagggaag atatgcgaaa tttgatcagt
      841 tgaatcgcgg tctattgatc gctgcgcttg tctttagttt gctaagtcgt tggttgccct
      901 atagaatcgg acaattgttg ttcatcgtct ttttcggatg gatgatattt cgtttcctat
      961 caaaaaaaat ctaccccaga ctaaatgaga atcaacgtta tttgaaatat cttgatagag
     1021 tcaaagaaaa atatcatcag ataaaaaaca aaaagcaagt caaaatggat cgaaaaagtt
     1081 atactttttt tgagtgcccg aattgtcatc aaaagcagcg tgcacctaaa ggaaaaggac
     1141 gaatacgtgt gacatgcaaa acatgtggta taaaattcga aacgaatgtt taagggagaa
     1201 aagaatgaaa ttagtattat tacgtcatgg cgaaagcgaa gcaaattttg aaaattactg
     1261 gacaggatgg ctagatgtcg ccttaacaga aaaaggaaaa gaacaagcag cagttgccgg
     1321 tcaaaaaatg cttgaagccg gacttcaatt cgatgccgtt tatacctctg ttttgaaacg
     1381 tgcgattctt accggacaag tcgcactaga agaaatgggt cagttatggc ttcctataat
     1441 aaaaacatgg cgtctaaatg aacggcatta tggggatctt gtgggtaaaa acaaagataa
     1501 gatgaaagaa atatacggaa aagatcaagt aaaaacatgg cgcagaggat atacggaagt
     1561 tccgccgtta accgcagaaa atagatttga ccgcagatat gatcacttgg atccgcattt
     1621 gatcccatac ggagaaagtc tggaaatgac agtgaatcgg atcattccct tatggcaaga
     1681 tcatctagca ccaaaactaa aagatcggca agatttacta gttgtgggtc atggtaatag
     1741 catccgagca ctgacaaaat atttagaaga tgttcctgaa gatcaaatgg atacgatcga
     1801 tatcccaaat gcacaaccaa tccagtatac attagcagat gatttgacaa ttctggacaa
     1861 aaaaatactt taaagaacac ctttatctaa aagtgagaga tagaaaaaag aagcaaagga
     1921 atggaacaaa aggaacatga aaaattatat atgggacttt gatggtacat tgtttgatac
     1981 gtatcccgca atggtagatg gtgcatggca agcactaaaa gattttggta tcagtatgga
     2041 caaaaaagaa atctacttca aaatgaaaaa gtattctact agttatttga tcaatgaatc
     2101 aaacttgaat gccagagagt ttaatgaatt atttcaccga tatgaaaaag aaagtacgga
     2161 agtttcccgt ccatttccag aaacgaaaca agtactggaa atgctaaaag acaacggcgg
     2221 tcgtcatttc atcctgaccc accgtttgac agaatcaaca tggggcctgt taaaagaaca
     2281 tcgattggca catctgattg aggaagtagt agggatcgat caggactttc ctcgtaaacc
     2341 tgatccagca tctttaaatt atttgatcga tacttttcat ttagaaagaa cagacacgat
     2401 gatgatcggc gatcgtcgtt tagatatcga agcagggaaa aatgcaggag tcgctacttg
     2461 tctttacgac atcgatcatt ttctgggtga gatcccggca gattatgtgg taggaaatct
     2521 gaatgaaatc cttaccttgc agagcatcat taaaaagtag tatccccttt caaaggagat
     2581 atgttataat tttcataaag gagtgataaa attatatgga aatcagaaga caaaaagaag
     2641 ttgtagaagc atttcattat gatatgagat tgccgaacca agaagtagaa acagatttga
     2701 aagtaggctt ctcgccttta aaagaaacga tcgaaaacta tccgaaagaa catagcatcg
     2761 taggagcacg cttagagttc cgtttagtgt ttgatacata tgttttatct ggaagtgtga
     2821 gtcagatcaa tcatatcctc aatcggaaaa ttgaaggtca aaatgatgtc acacaagaag
     2881 aagtggacga gctagtagca ccgttattcg atatcgtacg ccgaatgtct tatgaggtga
     2941 cagagatcgc cttagatcag cctggggtaa aattgaattt tcaatcagaa aaacaagaat
     3001 agacagtaaa aacatacctg cgatagatta aagctatcac aggtatgttt ttttattact
     3061 aattgtaagc aaaaagaatg tcatttcgat aaaaatcgtc taaaatataa aagtcactga
     3121 aaaaaatttt ttcaggagga tggttgaaga atcattctcg ggaaccttta cttccttcga
     3181 tggacttgtc attaataata tgaggaggag aaaaatgaca acactcatca cagttttagt
     3241 ggttctagtt tttgcggcat tattatatgt gttctatcgt atgcaaaagc gccatacaaa
     3301 attttcaaca cgcgtcttta cagcattagg agttggtatc gtctttggcg gtctgcttca
     3361 attgatcttt ggtgtagacg acaaagtcgt tactcaatca atggaatgga tcgggattgt
     3421 aggtcaagga tatgtatcat tcttgcaaat gctagttatg cctttagtgt ttatttcgat
     3481 cattggtgca ttcacaaaaa tgaaagtttc tgaaaagcta gggaaaatta gtgcgactgt
     3541 attgacttct ttacttggaa caacagctat tgcagcattg atcggaattg gttcaacaat
     3601 gctgttcgga ctccaaggag ctaaattcac acaaggagct gcagaaacag cacgaatctc
     3661 tgaactggca acacgtcagg aaacagttga aaacttatcg attccacagc agattttatc
     3721 ctttatccct aaaaacgttt ttgctgattt agcaggtagt cgtgcaacaa gtacgattgg
     3781 agtcgttatt ttcgcggcat ttgtcggaat cgcttatcta ggcgtgaaaa gaaaagcgcc
     3841 aaaagaagca gcattctttt cagatttagt cgacagtctg tataaaatca ttatgcggat
     3901 cgtgacgctt gttttgcgtt tgacacctta tggagtattt gctttgatga caaacgtttt
     3961 ggcaacaagt gattttgcag ctatcgtcaa tttaggtaaa tttgtcgttg cttcttacgt
     4021 agcattgctt gctgttttga ttgtccactc actgattttg attggtgcaa aagtcaatcc
     4081 aatcaactat ttcaaaaaag cctttccggt attgagcttt gcgtttactt cacgttcaag
     4141 tgctggagct ttgccattga atatcgagac tcagacaaaa gctttaggag tagatgatgc
     4201 aacagctaat ttctcagcaa gttttggttt gtctattgga caaaacggct gtgctggcgt
     4261 ttatccagct atgttggcaa cgatcgtcgc accagcagct ggagtgaatg tctttagttt
     4321 ggaatttatt ttgatgcttg tggcaattgt aacaatcagt tcttttggtg tagctggagt
     4381 cggtgggggc gcaacatttg cttcactgat cgttttaggg gcaatgaact tgccagtagc
     4441 aatcgttggg ttagttatct ctgttgaacc attaatcgat atggcacgta cagcagtaaa
     4501 cgtcagcggt agcatggtag ctggtatcgt gacaagtgca cgcatcaaag atttagatcg
     4561 cgatgtcatc aatgatgatt ctaaagtgat cgatgtgaat gcatagtcaa aaagaggttg
     4621 tgatagaagt ggtcagcttt aagaaataag aagaagtttc ctaaaaatag tttctcaaat
     4681 ttttgtgaaa tttcggctta tttccgagaa gctacttctg aaacaccgtg aataagaggt
     4741 tgtgaaaaag ctgccctgca tcaagtaata agaacagcca aacaaaaata gttcctcata
     4801 ttttacgttt ggttgagctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
     4861 aggtcgtgag cctgccgttt cactctgagt cacaaagagc aatttcaaaa aatagcttct
     4921 catgtttgtt gaatattgtg tcttgtgacc gaggagttgt caggagaaca ccgtttacca
     4981 gaggttgtga cttgttttta gtcacgacct ctttttttat ttattccata taaatacaca
     5041 ttatttattc cgaaaagtga aagcgcaaat aacaaaaaca accaacttat ttattattaa
     5101 agaaaagcgt atttaagtag gacgattctg ttgagagctt tcgtagattt tcccattttc
     5161 ctatggtaaa ctgacaaagt tgagaatgtt agaacagatc gtttaggagg aaacagatgt
     5221 ttacgaatga aataaaaatc atgctttatg tggacgatgt agaaaaaaat gcaacgtttt
     5281 ggagagcagt tggctttgcg gaaaaagatc gtcaagaaat ggatgggacg cttataattg
     5341 aagtaggagt tgaggacagt caaacctcat ttctgttata tgatcgagca tttgttgagt
     5401 cccattcacc tggcacagct actagtgccc catctttgat gttttacagt aaagatatct
     5461 ttggactata taaaaaaatg cagacgcaat cagtcacatt aggtgatatg gtacagcttg
     5521 gagaagaata tgtctttaac tttgctgatc ccgatggcaa ctactttgcg gttacaggta
     5581 aataatagaa ataaagactt tgtttttctg tgcgaaacag gaaagcgaag tctttttaat
     5641 tcaaataata atattatgta aacaaaaaac tttccatgcg taattataca caagcaaata
     5701 aatcgtcaaa tgcgaacgcc ttctttatac tgtttaggaa cgaaaagaag gaaggaagaa
     5761 atacatggat tatcaagtac tgctttatta caattataca aaaatcgaag aaccagagga
     5821 atttgccaaa aatcatttag ccttttgcaa atctttggat cttaaaggtc gtattctagt
     5881 agctgaagaa ggaataaatg gtactgtgtc tggaaccgtt gaaaacacga ctgcctatat
     5941 gaaagcaatg aaagctgatc ctcgatttgc tgatacgatg ttcaagatcg atccaagcga
     6001 aggacatgcc tttaagaaga tgtttgtaag ataccgtcca gagcttgtaa gtttaaagct
     6061 agaagaggac attgatccaa accaagtgac aggtgcctat ctttcaccgc aagaatttaa
     6121 agaagctatt ttagatgaac agacagtggt gattgatgca cggaatgatt atgaatatga
     6181 cttgggacat tttcgagggg ctgtacgccc agatatacgc agttttcgag agcttccaga
     6241 ctggatccgc gagcacaaag aagaatttat ggaaaaacgg gtagtgacct actgtactgg
     6301 tggcattcgt tgcgagaagt tttctggttg gcttgtccgt gaaggattca aagatgtcgg
     6361 acagctgcat ggcggtattg ctacttatgg taaggatcct gaagtccaag gagaattatg
     6421 ggacggcaag atgtatgtgt ttgatgaacg gatcgctgtc gatatcaacc aagtagataa
     6481 acaaatcgtc ggtcgcgact ggtttgacgg aacaccatgt gaacgatata tcaattgtag
     6541 caatcctgag tgcaatcgtc agattcttgc ttccattgaa aatgaagaaa aacatttagg
     6601 agcatgtagc atagagtgtg cgaaacatcc gcgcaatcgc tatgttcaag accatggaat
     6661 ctctccagaa gaagcagaac tgcggtttac agctttaatt aaatagaaaa caatagtttt
     6721 gattgtcgac catttccaat atgcgctata ctagcgttga ggatggtgat ccacatgaaa
     6781 tcattgattt atgctattgg ggatgtccat ggcaaacatg agctttttga aaaacttatt
     6841 cactattatg atccaaagat ccatcagctt gttttattag gggatctcaa tgatcgaggt
     6901 cctcgtacaa aagaatgttt tttattagga aagcaattag tcgaagaaac aggagccatt
     6961 tacctccggg gaaaccatga agaatatttt ttgcaatttc tgcaatcacc ggaggactgg
     7021 tatgcgcctt atatgagaaa tggtggaaaa gaaacgtttg aaagcctgat tcacccaggg
     7081 gcatcggagg aatactcccc aactgaaatc tcgatgatga tccaatcgag atattcagaa
     7141 ctgattaaat ttttagtcca gcgccccttg tattatgaat gggaaaatta tctttttgtc
     7201 catgccggtg tggatttgac aaagaaagac tggcgtaaga caagtctaag agactttatt
     7261 tggataaggg aaccatttca tgaagggaaa aacaatacag gtaagacaat tgtatttgga
     7321 catacgatta caccaatgct ccatggagat atgcagacaa cagacctctg gattcaggat
     7381 cataaaatcg gaatggacgg tggggctgta ttcggagggt cattgcatgg ggttgttttt
     7441 gacaaggaag gtattcttca agatattgaa tatcagaaca acgaaggacc ttggcatgga
     7501 atctgactaa tggaaagaat gaaggagctg tgactttgtt gcggctcttt ttatttttat
     7561 agagaatatt gtttctttca gtagtttaac ccaggataaa aagtatgata gaataaagaa
     7621 gcaattttta gcagaaaaga ggcattttaa tgacggaaaa tttgaaccag acgatcattc
     7681 agcttgtaca aaaagaactt tcagactatc gtcctaagca gttgactact gtacttaatt
     7741 tgttaaatga aggaaacact gttcctttta tcgcgcgtta ccgaaaagaa atgactggaa
     7801 gtcttgatga agtccagatt cgtgaaatcg aagagcggta tgcctatctt gaaaacttag
     7861 aaaaacgtaa aactgaagtg attcggctaa tcgatgaaca agggaaactg actcccgagt
     7921 tagaagcaga aatcacccaa gccgtgaaaa tgcaacaagt ggaagatttg tatcgtccat
     7981 acaaacaaaa acgacggaca aaagcaacga ttgctaaaga aaaaggactt gaaccactcg
     8041 cgaagtggct gatgcagctt acagatggag aggtgcaatc tgaagcagaa aaatatattg
     8101 acaaagaaaa agaagtctct tctgccgaag aagcgttgca cggtgctcat gagattattg
     8161 ctgaacaagt cagcgataat gcaaaatttc ggacttggat tcggtcttat acgtataaca
     8221 aaggtatgta tgtcagcaat gtcaaggatg agcaagcaga tgaaaaaggc gtatatgaaa
     8281 tgtattatga ctttgcagaa cccgtccata aaatggtttc tcatcgaata ttagctacta
     8341 atcgtggaga aaaagaagat attctgaaag tattctttca agtagatgaa gcagcaattt
     8401 tagcttactt ggatcgccaa atagtcaaaa atcctgcctc tccttcttct tcattcgtca
     8461 gagaagccta tcaggatagt tataaacgct ttattcagcc agcaatcgag cgagaactgc
     8521 gcaatgaatt gactgaaaag gcagatgagc aagcaatcgc tattttcggc gaaaacctcc
     8581 gtaatctttt gttgcaaccg ccactaaaag gtaaagttgt cctgggattt gatccggctt
     8641 atcgtactgg atgtaaacta gcagtcgtag atgcgacagg gaaagtttta gcaatcgaag
     8701 ttatttatcc tcataaacct gcagcgcaag caaaaagaga agctgctgga ccagctttta
     8761 tccaattaat taataaatat caagtagata tggtagctat cggaaatggt acagccagtc
     8821 gggaatctga actttttgtg gctgagcagt tgaaatccgc cgaccataaa acctattacg
     8881 ctatcgtcaa cgaagcaggc gcttctgttt actccgctag cgaaattgca cgaaaagaat
     8941 ttccgcatct acaagttgaa gaaagaagtg ctgtttctat tgcccgtcgc ctgcaagatc
     9001 ctttagctga attagtcaaa atcgatccta aagctgtcgg agtaggccag taccaacatg
     9061 acgtttctca aaaacgtttg gctgaacaat tggattttgt tgtggaaaca gcggttaacc
     9121 aagtaggtgt ggatgtgaat acagcaagcc cgcagctctt gcagcatata tcaggattga
     9181 ataaaacaac tgcccaaaac attgtcattt atcgtgaaga aaacggagaa ttcaccgcac
     9241 gaactcaatt gaaaaaagtg ccacgcttag gaccaaaagc atatgaacaa gcaatcggat
     9301 tcttgcgagt ccctggtggg aaaaacattt tggacaacac aggtatccat cccgaaagtt
     9361 attctattgc aaaagaaata ttaacttcag tccaactttc agaaaaagag cttggtacag
     9421 aagaagcagt agaaaaattg acacgattat ccgtagagaa actggctgaa agcctatcag
     9481 tcggagaaga aacgttagcc gatattttag ctgggctgac acaacctgga cgagatatgc
     9541 gtgatgagat gccagcgccc ttattacgta cagatgtatt gagtatggaa gacttgaaac
     9601 cagggatgga attgactgga acggtccgta atgtcattga cttcggcgca tttgttgata
     9661 tcggtgtgaa gcaagacgga cttgtccata tatcgaaact cagcaaaaaa ttcgtcaagc
     9721 atcctacaga tgtcgtgtca gtaggagata tcgtaacagt ttggatagaa caagtcgata
     9781 cgaaaaaagg cagaatcagt ttgacgatgc tttcccctta tgaagagtaa caatgaggag
     9841 taacaaaaat tgacacaaga agaactgcag cagttagtag aagagatatc attaaaaagc
     9901 ttccagcttc ctttcaagca ccaagcaatg ttcaatccac gcttacgtac aactggcggg
     9961 cgctatcatt taaacgatca tcatttagat tttaatgcga agctatttga agagtcagac
    10021 gaagagacga ttgcaggaat catcaaacat gaactttgcc attatcatct tcatctagct
    10081 ggaagagggt atcagcataa agatatggat ttcaagtatc ttttgaaaaa aacaggaggg
    10141 ttgcgctatg caccagcctt gacgaagaaa cagataaaga tggagtatta tcgatgccaa
    10201 gattgttctg ccacgatctg ccgcaagaga agaatcgatg tacgcaaata tcgttgtgga
    10261 agatgtcatg gagaaatcaa atggattgag acaaaaagag aagactttaa tgaagcacaa
    10321 aaaatcagat gaaaggatag aaggcctttg gaaaaaagtg agcagaggaa tctaaaagac
    10381 tggaatcagc tattaaattt tttagccgca cctgaagagg gaaattttga ggaactgacg
    10441 gcacctacac ttattttagc tggaaactgt cttcctatct tagctgataa agcagcacaa
    10501 atgtatttaa atggccaagt agatcaattg tttttggtcg gaggggtggg gcatgcgact
    10561 agaatccttt atgagaattt tgaaaagcaa ggatttcatt ttgaagatgg catgagtgaa
    10621 agtgaaatct gtcgtcagta tctaaaagaa gtctatgatt tgcccgataa ggcttttctg
    10681 atagaatcga agtctacaaa ttctggagag aacgccactt tttcactgga gattcttcat
    10741 tccttaggag ctgtaccaga aaaaatctta ttgatgaatg atccgacact gcaacgcagg
    10801 actcgagcaa cttttgagaa agtatggcaa aatgaacaaa ctattttcgc gaatgctgtg
    10861 ccatttgtgc cggaaatcct tcacttttct gaagagatca tctttacagc aaaagaactg
    10921 aatcatcaat ggcctaagga atatttccat gcgctagtat taggagaaat ggaacgtctc
    10981 catgacgatg agaacggcta tggtccgaaa ggaaaagatt ttattcctca cattgatata
    11041 tcagaggaag tttggtcttc ttacaccaga attaaagagt caataaaaac ggatttttct
    11101 cgtacttgac cattttagca agcgaatcct cctttccaaa taaatttggt tgaaattttc
    11161 aatcgtttat aagataatga ggagcgtgtt gaatgtaata gctaaaagaa tggacgctag
    11221 ataagagaag aggattcaaa tggaaaatca aaataaattg tatcattttg ttggtatcaa
    11281 aggttcagga atgagctcct tggctcttgt tttacatgaa caaggtctaa atgtccaagg
    11341 atcagacatt gaaaaatatt tctttacaca aagagattta gaaaaagcaa atatcacgat
    11401 tctgccattt aacgcagata atgtaaaacc agggatgacg atcattgcag gaaatgcatt
    11461 tcctgattca catgaagaaa tccagcgagc aaaagaatta ggtttggaag tgattcgcta
    11521 tcacgacttt attggtcatt ttatccaaaa ttatacgagt atcgctgtaa caggctctca
    11581 cggaaaaaca agtacgactg gactgctctc tcatgtattg agtggtgtcc gtccaacaag
    11641 ttatctaatt ggagatggaa caggacatgg tgatccgcaa gcggaattct tttcatttga
    11701 ggcctgtgaa tatcgccgtc atttccttgc ctattcacca gactatgcaa tcatgaccaa
    11761 tatcgatttt gatcatccgg attattatac aagtatcgac gatgtattta cagctttcca
    11821 aacaatggct ggacaagtga aaaaagctat ttttgcgtat ggtgacgatg cttatttacg
    11881 caaattaaaa gcaaatgtgc cgatttatta ttatggtgtc acagaaaacg atgatatcca
    11941 agcacgaaac atcgaacgca caacttctgg ttctgctttt gatgtctatc atggggatga
    12001 atttgttggg cacttcactg taccagcatt cggtaaacac aatatcttaa atgctttagg
    12061 tgttattgca gtagcttatt tcgaaaaact ggatctgaaa gaagttgcag aagaaatgct
    12121 gactttccca ggagtaaaac gtcgattcag tgaaaagatc gtagcagaca tgaccgtagt
    12181 cgatgattat gcgcatcacc ctgcagagat caaagcaacg attgatggcg cacgccaaaa
    12241 atatccagat aaagaaataa ttgcagtttt ccaaccccat acgtttacgc gtacgattgc
    12301 attgatggat gaatttgcag aagcacttga tttagctgat aaagtttact tatgcgatat
    12361 ttttggttcg gctcgggaag aacaaggaaa cgttaagatt gaagaccttg gagcgaaaat
    12421 caaaaaaggt ggagaagtca tcaaagaaaa taatgtatct ccattgttag attatcatga
    12481 tgcagtagta atcttcatgg gtgctggaga tgttcaaaaa tttgaacaag cgtatgaaaa
    12541 acttttaagc agcacgacga aaaatgtact gtaatacaat tactgcagtg tccttataaa
    12601 aatagaaaga gggggagtgg caaaaatctt gccaagcccc cttttttgca acttatgata
    12661 aacggtgttc aaaagcttgc atctgcggta ataagcccaa tcaaatcaaa aacatgagaa
    12721 gctgtttttt cttggctgtt cttattattt gatgcaggac agctttttca cgacctctgt
    12781 aaactatagg aatctgttaa atcaagggag cagaacttgc cttttacgct acttttggta
    12841 caataatgta tgattaaaaa taaactggag ggtttctatc ttgaacatag gtaagccgag
    12901 aaaactagga aaaacaataa atgaaatcga ggaaggcgac tcgttatcct taacagaatc
    12961 tattgaagat aaccagcttt tgctgtattt gggattgacg aatgatgcaa atcctttgta
    13021 tatccaacat gactttgcac aaaaaacaga atatcaacag ccaatcgttc catcagtgat
    13081 gctgatgggg atcatcacaa gtgcaatttc aaagcatctt cctggaccag gatcacatgt
    13141 tgtcaatttt tctgtcaatt ttattgaacc ggttttccat tatgaaacac tgacttttca
    13201 gtttgaggtc ataaaagtag ataagatgaa ggatgtggtg acgatttctg tagaagcgga
    13261 gaatacgaac gaagatcgtg tgttggatgc tgtcgttatg gtccaaccgc cacaagttcc
    13321 tgaattggaa atagcaatcg aaagtgaagg tgaattgaat gaataatcca agtacatcaa
    13381 tgtcaggtat caatcgtttt tatgcaaaag tttatggatt tttaggtatg ggacttgccc
    13441 ttagtgcagt cacttcttac ttggctcttt gggtatttcc tttgcaatta gcaactttta
    13501 tcaataattt tccactaggc tttgtgggtc tgtggatcgt tgaactgatt ttagtaatgg
    13561 ttctaggcgt aaaagcacaa aagaatccga gcttagcaat cggtggattt attgcctact
    13621 ctcttttgaa tggcataaca ttagcggtta ctcttgcata ctacgatatt ggaacagtaa
    13681 cgcaagcttt cttgacagct actttgatgt tcatggggat gtctgttgtc ggagtaacaa
    13741 caaaaagaga tcttagcggg gttggaagag caggacaggc agctttaatc ggagtgatca
    13801 ttgcactagt cttgaacatc ttcattttga gaagtagcgt agttgagctg ttcatctccc
    13861 tactgttagt cgtcatcttt gcagggatta cagcttatga taaccaaagc atccgtaata
    13921 tctatgtcca gacaaacgga acagcacata gtggaattgc tgtattcatg gcattgaagc
    13981 tgtatttgga ctttatcaac ttgttcttgg cgtttctgag aatctttgga cggaacaact
    14041 aaaaaagaaa aaaattcatc agttggggct ataccgaatt atttggtatg gtcccgcttt
    14101 ttcttttcgc attccgcagg attctttgtt agaatgaata agaactttac agtaaggagt
    14161 taagaagatg acaaaaaata aattattact cgttgatggg aacagtgtgg cttttcgcgc
    14221 attctttgcg cttcacaatt ctcttgaacg tttcaaaaat agaaacggtc ttcatacaaa
    14281 tgcaatctat gcattcaata cgatgtttga aaatgttatg caaaaagagc aaccgactca
    14341 tgttctggtt gcgttcgatg caggaaaaac gacttttcgg acagaaatgt atgcggagta
    14401 caaaggtgga agatccaaaa cacctggcga attcaaagaa caaatgccat atatacgtga
    14461 tttgttgaca ggactagggg tacagtatta cgaattgccc aattatgaag cagatgatat
    14521 tatcggtact ttggcagaaa aagtagacaa agatcaattt gatgtcgtcg tgctttcagg
    14581 tgatcgggat ttgactcaat tagctagtaa agaagtaaaa gtggatatca ctgtaaaagg
    14641 tgtcagcgat atcgaaagct atacaccaga acatgtagcg gaaaaatatg atgggttgac
    14701 gccaaaacag attattgaca tgaagggact agccggagat gcctctgaca atatccccgg
    14761 tgtgactaaa atcggtgaaa aaacagctat caagctattg aaacaatatg gctcagtcga
    14821 aggaatttat gaacatatcg atgaaatgaa gcaaagcaaa atgaaagaaa atctgataaa
    14881 tgacaaagag caggctttct tatcgaaaaa attggcgacc atcaatactt cagcgcctgt
    14941 ggatgtctct atcgactcat tgaagtatga agggaaaaat ctcgataaac tcgttccgtt
    15001 ttataaagaa atggatttca atcagttcct ttctaaattg aatatcgtag aagaagaagt
    15061 aaaaatggat gatattttgt ttgaagtcgt tcatgaattc aaagaggaaa tgtttactac
    15121 ggatatggcg ttgtacgtgg aaatgatggg cgacaattat catacagagg aaatcgtcgg
    15181 agtagcgtgg gggacagaaa agaaaattta tgtcacgaac gatctatctg tattcgaaaa
    15241 ccgagcgttc cattcttgga tcactgatcc gactcggctg aaaaaagtat atgatgcgaa
    15301 acgaacttat gttgctttaa accgctatac tggaaaaacg aaaggaatcg attttgatgt
    15361 cttgctaggt gcataccttc tcgatacgaa tgaaaaaagc acagatatcg aaggaatagc
    15421 tgctcattac ggatacaacg atatccaatc agatgaagct gtatacggca aaggggcgaa
    15481 aaaaggttta ccagaagaag aggaactctt ttttgctcat ttagcgcgaa aagtagctgc
    15541 aatcaatgcg ttgacaccaa aattgagcca agaactggca gaaaaaaacc aagaagatct
    15601 tttccggaaa atggaactgc cattgtctat cattttggca gagatggaaa taagcgggat
    15661 caaagtagat gcgactcgct tacaagaaat gaagggcgag ttctctgctc gcttaagaga
    15721 gatcgaacaa aaaatctacg aagaagccgg cgaagaattc aatttgaatt caccaaagca
    15781 attaggagtg atcttatttg aaaaaatggg attacccgtt atcaaaaaaa caaaaactgg
    15841 atattccaca gccgtagatg tactggaaca gcttcgtgaa caagcaccaa tcgtagagga
    15901 tatcctcacc tatcgtcaaa ttgcaaaaat tcaatctacc tatgtcgagg gactgctgaa
    15961 agtgatccaa tcagatggaa aagtgcatac ccgttatgtc cagacattga cccaaacagg
    16021 acgattaagc tctgttgatc ctaatttgca gaacatcccg attcgattag atgaagggag
    16081 aaagatacgt caggcatttg ttcctagaga aaaagactgg ctgatttatt cttctgacta
    16141 ttcacaaatc gagttacgcg tacttgcgca tatctcaaat gatgaacatt tgaaagctgc
    16201 cttcctagaa ggtcaagata tccatgccag cacagcgatg cgtgtatttg gaatcgaaaa
    16261 ggcagaggat gtcacaccaa atatgcgtag gcaggcaaaa gcagtgaatt ttggtatcgt
    16321 gtatggcatc tctgattacg gactttcaca aaatctagga atcagccgaa aagcagcaca
    16381 gcaatacatc gatacgtact ttgaaaaata cccaggtgtc aaagaatata tggaaagaat
    16441 cgtacgcgaa gcaaaagacc aaggctacgt cgaaacgctg tatcaccgcc gtcgatatct
    16501 gccagacatc aattcaagaa attacaatat ccgttctttt gcggaacgaa cagctatcaa
    16561 tacaccaatc caaggaagtg ctgctgatat tttgaaaatc gcgatgatcg aattggataa
    16621 acgattaaaa gaaacaggtc ttcaagctac gatgctgtta caagttcatg atgaacttgt
    16681 cttcgaggta ccggaaaaag aacttgaatc attagataaa ttggtgaagg aagttatgga
    16741 acaagctgtt tctcttcatg taccactgat cactgacagc agttggggaa aaacgtggta
    16801 cgaagcaaaa taaacattgt ttaagacaga gcaatataat gaaggtgaaa agaaaaaatg
    16861 ccagaattac cagaagtaga aaccgttcgt aaaggattgg aacggttagt agtaggaaaa
    16921 acgattcaaa aagttcaggt cttgtggccc aagatcatcg agcaaccaga gacacccatc
    16981 tttgaggctt ctcttgttgg cgaaaccatc caatccattg gacgtagagg gaagttttta
    17041 atttttcatc tcgatcattg tgaactgatc tcacacttgc gaatggaagg aaaatatcaa
    17101 tttacgaaag aaaatacacc aatcgataaa catacgcatg tacttttctt ttttgaggat
    17161 ggaagccaac ttcgctacaa cgatgtacga aaatttggtc gtatgacaat cgtcgaaaaa
    17221 ggagcaagtg caacttaccg aggaatcatg aaattgggac ctgagccttt gccagatagc
    17281 ttcttattag cagatttcgc aaatggactg aaaaagtccc acaaagcaat caagccattg
    17341 ctgctagacc aacgtctagt gactggtcta ggtaatattt atgtagatga agcattatgg
    17401 gaagcgaaga tccatccaga acaaccggcg aacacactgc gccccaaaga ggtagaacaa
    17461 ttacgtctat cgatcattga tgttttggat cgtgcaatag aagccggagg taccacgatt
    17521 cgcagttatt tgaatgcatt aggagaatca ggcggatttc aagtagcact gcatgtctat
    17581 cagcaaactg gcaaaccatg tatacgttgt ggaacgccga tcgtgaaaac aaaagtggca
    17641 caaaggggga cgcactattg tccgaattgt caaaggctaa aaatcgcaaa gtaggatttg
    17701 ttttaggttt gacgggtgga atagctaccg gtaaaagtac ggcagccaaa gtctttcagt
    17761 ctcatggatt tcctttgatc gatggcgatg tgattgccag agaaactgtt gagcctggaa
    17821 cgcttgctct gaggaaaatt gtatcagtgt ttggccaaga ggtattgcag cctgatgggc
    17881 aactagatcg agggaaactt gggatgattg tttttccatc aaaggaaaaa cggcaaaaac
    17941 ttgatcagct attagatccg tttatccgaa aagcgataaa agatcaaatc gcctctctaa
    18001 gttccaatca tcctttagta attgtagata tcccattgct ctacgaaggt cattatgacc
    18061 actatatgga tgcagtagct gtcgtttata ctacgccaga aactcagctt cagcgtttga
    18121 tgaaacgtaa tcaactgacg ctagaacaag cgcagcagag aattagtagt caacttccaa
    18181 tcgaagaaaa aaagcagcgt gcggatattt tgttcgacaa caatggaaca aaagaaaaac
    18241 ttgtgggaca aatcgaaaat tggctttttg ctaatcgctt tctttgagta tctgtgtcaa
    18301 ttttgctatc ctgagtatat agaaagtgag ggatagcgat gggatcatta aaaaatcaaa
    18361 aggataaagt cgtaggtaac gcaaaagaaa aaatcggcga gatgctcaat aaagaaaatc
    18421 taatcgatga aggtcgtacg caatcagaaa cagcagaaga aaaagaaaag cagtaccaag
    18481 caagaatcga tgaaatagaa gaccagcagg cagaagaaga agcgaagcgg caagatttga
    18541 ctcaagaacg aaaaaatccg acacctgatc gtagtaaaac accgctccca gaaagtgacc
    18601 acattcccga tgagcaaaaa atcgaggaac agcgaatgaa acactataca ggaatcgaag
    18661 agaagttata aaatagtaaa aaatcgagat gtgacttgaa gcagatgaga aggtgttcat
    18721 ctgcttcaag ttttttgtgc tagatgacta aatcagcttt tgtgtaagtt atttctcagt
    18781 aatcaaggtg atcagtattg gaaaattgaa atttagtaag gacaggggac acaattacgc
    18841 atgaaagtag aaaaaattgt tcttatatcc gtgttttttg ggtaggacag tcgcgtttgt
    18901 gatttgtttc gtgttataat acaactagtt gtaaagaaag acacatcctt tatataaaat
    18961 gcgatgcaag aggtgagaca aaatgagatg tcccagatgt caacataata attcacgagt
    19021 aatcgacagc cgtcaagcag atgatggacg tgcgatccgt cgccgtcgcg aatgtgagaa
    19081 ttgttcgttc cgattcacta catttgaacg aattgaagct gctccgttat tagtaatcaa
    19141 gaaaaacggg gaacgcgaag agttcaatcg cgataaaatt ttaagaggac tcatccgttc
    19201 agcagaaaaa agacctgtag ctatggaaca aatggaacaa atcgtcaacc atgtcgaaaa
    19261 ccgcgtacgc agtctcggag aaaacgaagt atcgacgaat ctaattggtg aatatgtgat
    19321 ggaagattta gttgatttag acgaaatcgc ttatattcgt tttgcaagtg tttatcgcca
    19381 gttcaaagat atgtctgttt tcttaaaaga gttgcaagat atcgtggata aagcaaaaga
    19441 aaataataaa gagaataata aagaaaacaa ttaagaaaca aaaaggaggc atttccttgg
    19501 aaaatgcttg gaaagagctt caaccaaaaa atatttacca aggaagaaaa gcggctccgc
    19561 tgagagaaga cagcaagaac gccttgctgt atctttatca gccactaatc ggcggagaag
    19621 ccttgagtat ctatttcacc ctgttatcag aaatctctca agaatctggc aaaggtcctg
    19681 aagggatgca tgcagatctg cttagtagtc taggctgcgg tatcccgcaa ttttatgatg
    19741 caagaaaaaa gctagaagga atcggcttac tggatgttta ttttaaagaa gatagtgatc
    19801 tgggacctcg ttttatttat gagctgttag aaccactcat tcctaaagca tttttcaaag
    19861 actctgttct ggcttttctt cttctggaaa aagttggtga acgacgattc cagaagctta
    19921 cccaattctt tgaacctaaa aggcatacag cagagggata tcaaaaaatc acaaaaaaat
    19981 ttttagatgt ttatcgcttc aatgaagcag tgtacgctgc taatcaagaa aacatcgaat
    20041 cgctgaataa atcttttgaa gaatctgaat cagtagcatt acttgaagca gattcgacat
    20101 tcgattggca gtttttgaat gattggctgg caaaaaaaca tattgcaagt cttgatgatc
    20161 caatcatcaa acaagtcgac atgtatcatc agctttacgg tttcgatgaa ttgacacttg
    20221 gcgaactgat cagtcaatct tatgacttta gtgaacaaaa agtatctgaa aaagaactgc
    20281 aaaaagccat tttggcaatg cagagacgtc cggtgaagca aacaaaagaa acagttgcgg
    20341 tttctgaaaa cagtaatgaa ccctcgtcaa acgaacattt gacaaacgca gcgcttcagc
    20401 tgataaaaga agcacagagc attccaccga tgaaatatct ggaagcaatc aagtcagaaa
    20461 aaggcggata tgtttctaaa caagaaaact ggttactgca agatcttgtt tctcaatcag
    20521 gtctttccag tagcgtgatc aatgttttgc tgaattatgt actagtgatc aagaataatg
    20581 ctagcttaaa tgccagttat gtaaatacag tggcaaatga atgggcacaa aagaaaatcg
    20641 ccacagcaga agaagcgatc cagcacattc ggcaaataag taatcaagca aaacaatcaa
    20701 aacaaaagaa gcaaacaaat tatcaaactg gcaagcgaaa tgttcgacgg gaaaagcttc
    20761 ctgattgggt caaccagcca aaagatgaaa aacagatcag cagcgagaaa aaagcagaga
    20821 ttgaccgccg ttttaaagaa tacctggcaa aaaaggaggg tgatatctag tggaagacgt
    20881 aggcaaagaa ttgaagagga tcatcagcaa acgcaattat caagaaaagt atgctgaaat
    20941 gatcgctgaa gtcttaaatg atgcggatgt tcaagctttt ctaagcgcac accaagaaga
    21001 attgacacaa gcggatattg aaaaaagtta cgctaaattg tatgaattcg tgcaagaaaa
    21061 gcgtaaatat caaaaaaacg atccaacgat gatcgctccc ggctatgagc cgaagctgac
    21121 gttgaatttt cattatgtgg atgtcactta tgtaccaacg gaagcattgt tagcacggca
    21181 aagacaagaa gaaatcagaa gccgagtaaa agcaatggat atgccaaaag atattcaatc
    21241 ggcttctttt gaaaactttg aacgtacaga tggacgagga tatgcgagct tagaagccct
    21301 agattttgta gagaaatata ctgctgatcc aaaagggtat cataaaggac tgtatctagt
    21361 aggaagtttt ggtattggaa aaacatattt attaggagca acagcgagag aattagcgat
    21421 tgctggattc accacgacgc tagtccattt tccgacattt gccgttgaga tgaaacaggc
    21481 aatcggaaaa gatcaagtgg cagaaaagtt agatgcagtg aaacgttcac ctattttgat
    21541 gatcgatgac attggtgcag atgcgatgag tagttggata cgagacgaag tattcggtgt
    21601 tatccttcaa tatcggatgc aggaacagtt accaaccttc ttctcatcga attttacaat
    21661 ggatgaattg gaacagcatt tgtccgtcac tcaacgtgga gatgaagagc cgctaaaagc
    21721 gaaacggata atggaacgca tacgttattt gacaaaagaa atcgaaatga ctggtcgcaa
    21781 ccgacgcaat ggttgaacag ttgacaagtc caactgacat ttgacctagt agtaaaagca
    21841 ggtcagcgaa tcattatatg gacagaaatg accggagaca atcaccgcaa caagtaatgc
    21901 agaaacttaa acggaggatt ttttatgagg gctatttttt ctagtatatc tgtagttggt
    21961 ctattttttc ttttagcagg ctgcggtagc gcagatagca acacaggttc tgttgattcg
    22021 attgatgcgg gtcaaacagt aaaaacaagc agtacgaaaa cggagagaca aagcatattt
    22081 gtcggaacga ttgaaagtat cactcaagta gaagcagaag aagaaacgct tcagttgaaa
    22141 ctcgtcgatg tcatggccaa agaagatcca gcgaatatgg gaacgtcatt cagcaatgac
    22201 ggagtgatct taaatgctac tgctgaaaaa ataagcgtgg acataaatga attgaaaatc
    22261 ggtgacaaag tccaatttac attagttgag atgccgatca tgacgatgtc tatcccaccg
    22321 caagttcctg gagattcgat tattgatgtt tcattgaaca aataaccaat aacatttttt
    22381 caaaaataag aaaatgttgt tttatagaac gaaaaggtat attttttaag gagatatggg
    22441 aattttttta ttcctagtct ccttatttta tttggaaaat gctataatta tctagaagga
    22501 gtgaagctat gaaccattta gatttatctc agcgcttagc cgcagtgggt gactttgtcc
    22561 ctgaatccgc tcgtttagca gacattggat cagatcacgc ttacttaccc gttgcattga
    22621 tattaagagg aaaaatcgaa tatgcagttg ctggtgaagt cgttcaaggt ccttatgaat
    22681 cagcacgtaa gcaagtcaaa aaagatggat tagaagaccg tatcaccgta cgccttgcaa
    22741 atggtctaga tgctatccag ccacaagatg gtattacagc tgtcacgatt gcgggtatgg
    22801 gaggttcact gatccgagat atcctagaag ctggcaagtt gaatcaacgc ttaagcggac
    22861 aagaacgttt gatccttcag ccaaacatcg gagagcgtac attacgatct tggctgcaag
    22921 aaaatcagta taaaatccaa tcagaaaaaa tacttgaaga aaataaaaaa atatatgaaa
    22981 tcattgtagc cgaaaaagaa caaaaaccag ttacttacaa tgaaatggag ctgatgttcg
    23041 ggccatttct gcttgaagag aaaagtgaga tcttcaaatc aaaatggaca agagagcttc
    23101 aacaaagaaa agctatccgt gaacagctca aacaagcagc taatcaagag gcacgtcaaa
    23161 aacaaatcga gcaggaaatc caaatgattg aggaggtttt aaagccatga caatcagcgg
    23221 acgcactttc atccaaaagt ttgaaagcta ttgtcctcag tggctagctg aagaaggaga
    23281 cccagtcgga ctgcatatcg gaacattgga taagccaatc caacgagtaa tgatgacatt
    23341 agacgttcgt ccagaagtgg tcgaagaagc aatcaagaaa aaaatcgatt tgctgattgc
    23401 taaacatcct ccaatctttc gtcctgtaaa acggctggtt actgatcagc cacaagaaaa
    23461 aatgtatgca gatttgttga aacatgatat tgccgtctat gcagcacaca cgaacatgga
    23521 tattatttgg gatggactga atgactggtt ttgtgaactt ctcggtattg aagtggagag
    23581 ttatttagta aagactcatg agattcatta taaaaaactg gccgtttatg tacctgtgga
    23641 tcatgcacag aaaatgcgtg aagtattagc tgcagctggt gctggtacac aaggtgatta
    23701 taccggtaca agttttacct cgattggaca cggtcgattt actccggaag ctggtgcaca
    23761 accagcgatt gggaaagtag ggaagacaga acaagttcaa gaggcaaaag ttgaggttat
    23821 tttgccggaa actatcgaaa aacaagtgat tcaagccatg cggtcagctc atccttatga
    23881 ggaacctgct tatgatcttt tcgctataga tgaaccagtc gaaatgtttg ggttaggacg
    23941 agtaggtgaa ttgccgcaag aaatttctat agaggcattt gtagaacaag taaaagaagc
    24001 gttccaacta gatggactga gaatagtcca gccaaaaaat gcaaaatcct ctgtgaagcg
    24061 cattgcgatt tgcggtggaa gcggtgaaaa attttatccg caagcaatcg cccaaagagc
    24121 agatgtctat atcacgggag atatctatta tcatacggct catgatatgc aaagcgctgg
    24181 gttgattgca attgatcccg gtcattatat tgaatcgtta tgcaagcaac gatttatcga
    24241 gaaatttgaa tcttggaaac aagaagaaaa ttgggatatt aactttttcg tttctgaaac
    24301 aaatacaaac ccatttcaat ttaattaaaa ggagagaata ctatgtacga aaatcttttg
    24361 ccacgttttt tacgatatgt caaaacagaa acacgctccg atgcaacaag caaaacgact
    24421 ccatcgactc agacacaagt tgcttttgcg caagaattga aaaaagaatt agaagagtta
    24481 ggcttagctg atgttttcta taatgaagat aacggattcg ttatgggaac attaccaagc
    24541 aatgttgatc atgaagtgcg ttccattgga tttatttccc acatggatac agcagatttt
    24601 aatgcagtag gagtcaatcc acaaatcatt gaaaactatg atggcgagtc tacgatcgta
    24661 ctagatgcgg aagaacgcta tacattgaat acaaaagatt ttccaaattt gaaaaattat
    24721 gaaggccaca cattgatcac aacagatggc agtacattac tgggagcaga tgacaaatca
    24781 gggattgcgg aaatcatgac tgcaatggag atcttgatca ataatccttc tatccctcac
    24841 ggtaccatca aagtggcttt tggtcctgat gaagaaatcg gtgtcggagc ggataaattc
    24901 gatgttgagc aattcgatgt agattttgct tatacagtcg atggtggtcc tttaggtgag
    24961 ttgcagtatg aaacgtttag tgctgctcaa gcaaatatta cgatccaagg gaaaaatgta
    25021 catccaggga cggcaaaaga tacaatgatc aatgctctac agttagcaat cgattttcat
    25081 aatcagcttc cagccgatga agttccagaa aaaacggaag gatacgaagg tttcttccat
    25141 ttgatggcat tggatgggaa tcctgaagaa gcttctatga gttatatcat tcgcgatcat
    25201 gatcgtgaaa aattcgaagc acgcaaagca caaatcacac atatccaaga agagttgaat
    25261 cagcgatttg atcaagaacg aatcaaagta gatatgtatg atcaatatta caacatgaaa
    25321 gaaatcattg aaaaagatat gagcatcgtg gaattagcga aacaagcaat gatcgagctt
    25381 ggtatctctc cagtgatcga accagttcgt ggaggaacag atggttcaaa aatctcttac
    25441 atgggtattc cgacgccaaa tctatttgcc ggaggagaaa atatgcacgg acgattcgaa
    25501 tttgtttctt tacaagtaat ggaaaaagca acagacgtga ttgtaaaaat tgcagaattg
    25561 aacacaaaga gttaaaatcg aaaaagaaca gcttatgaca aggcgttcgt cccaatgatg
    25621 gaatgtcatc tgtctaaggc taaagggcag gacaatggaa ttggttgtcc cgccctcttt
    25681 tttgaagagt aaataggagg taaagaatgg aaaagctgct agttttttat aacaaaagtt
    25741 cagggaaaga tgagggtgag aaattagcac gctggtttca agattatgta aaagaaaagc
    25801 agccagaatt atatgtagaa ctagctgaaa ctggcccatc gattgatgat gcggaattag
    25861 tcaagaaagc agaagccata gaagctgata ctttagtaat tataggtgga gacggcacga
    25921 ttcatcatat cgtccaagcg ttccaaaaaa cattatctca ataccatgtc ggattacttc
    25981 caggtggaac tgtcaacaac cttgcacgtg ttcttgagat tcccctcaaa aaagaagaag
    26041 ctgctgacgt gatcctggaa ggcaatgtac ggaaaataga ctatggtcaa gtcaatgatg
    26101 aagtcattat ctctacactg acaatcggaa tcttagcaga tacagcagtt tggatcagtc
    26161 aagaagaaaa acagcgttac ggctcgtgga tctttatcaa gaagtttttt aagttattgc
    26221 tgaagaagaa aaaatatcat ttggatttag aaacagacga ggagcattgg aaaggaaaat
    26281 cccaactgtt gacagtcacg atgtctaact ccgtgggcgg ttttacaaat tttgacgact
    26341 cagcgaccct agatgatgga aaatttcatg taacgatcgt accttcctta gatattttcc
    26401 gatttatttt ttatttgcct agaatcatga gaggcaaatt ctatacgatc cccggcatta
    26461 cttatttcac agccaaacgc atgaaaatcc aagcgcagga aaaatctgtg ggcactcgaa
    26521 cggatggaga cacgacagat gatcttccag ttgaattatc tgttgtatca aaaggattaa
    26581 cagtttattc accaaagaaa gaagaaaaag cttagaaata gtagttaaca gaaagttgga
    26641 agaagagtaa tggatgtatt gttacacaat cctttgtggt tttacctttt cattgtgaat
    26701 ttttacttat tttgtctgat ggggtatgat aaacatcagg ctagaactag cggctggcgt
    26761 gttcctgaga ataatttgat atttgtcagc ctgttaggcg gtggtttggg aggattgatc
    26821 tctcgaaaag ttttccatca taaaactcgg aaaaagaagt ttactatagg attcgctgca
    26881 ggtgtacttg ttgatttgat tctcatttat tttttccatt aaggagcagg agatgtcgtc
    26941 taaaggaacg aaaactaaaa tcattctgaa tctgcttttg ctgattgtga tttttgccat
    27001 tatttattat ttaatcaatc aatcatttgc agatatcttt gccgaattgc tgtctaccag
    27061 tgttgttgtt ttggcagcgg ctgttatatt agggacagtt taccaaatcg ctgaagggcg
    27121 ctcaatcaaa gaaattgctg aacctttcgc gccgaatttt acaacgaaag atgggttctt
    27181 gacctctagc tatattgcgt tttaccgaat cgtttcgttt ggtacaggaa cgctgatctc
    27241 ggagatttat ttttataaca aaaaaggaat gaagctatcc cagggagcag gggtgacagc
    27301 actccatatg attatgtaca aactggcagt gatcacttat gcattagctg gcttggtcat
    27361 ccaattctct cttttttatt ctaatggtcc atcaatgatc tggtttatca tcgctggtat
    27421 ccttttgacg atcgtgattg ttgccttttt attggcgatg tccgtcagct tgaatgttca
    27481 aatatttttt gtcagcttat cgaataagtt atttaaaagt gagcgtttgc ggaaatgggt
    27541 ggatacatgc aatcagcaga tctactcttt aagggaaacg gtccaaacca ttatccaaga
    27601 caggactgcg ctattgcgga tttatctatg gaatatgtta aaacttgtat tttggtatgt
    27661 acttccttat ttgattctga ttgaaaacca tcctaaaata gattttctac tgaccatttc
    27721 gtttatcagc tttgcagtag tgctttcagg ggttattcct acgcctgctg gtattggttc
    27781 ctttgaattt gtctatttgt tattattcag accagttgtt ggaacagttg acgcagtttc
    27841 ttcgctttta ctgtatcgtt tcagttcctt tatcttgcca tttctctatg gatttgtgta
    27901 tgtgattgct gaacggcgaa gagtgatcaa agaagaaata atagaagtaa aaaaagagaa
    27961 taaagaaaat caagggtagg tcttttataa gatctaccct ttttatcaaa tcaaagaaaa
    28021 acgttatgga taagataatt ttacgtttgt ttggctcttt ttttatatac atacaatcaa
    28081 ttttgttttt ttaagattta tataagtcga gaaaaaaagt caaaaaacta tgtgtatatt
    28141 ttgaccaaaa ttgaccaaag cgatataata gtttttgtaa agatcaaaga aataagtgat
    28201 cttaccttta attaggaggg tatacctgta tgaatattga gaaaatgact acgacgcttc
    28261 aagaagcgat tgctgaagct caacagattg cggtcactcg aaaacatcaa gatatcgaca
    28321 ttgcccatgt atggaaaatc tttttacaat ctaatcattt tggtcgaaat ttctatacgg
    28381 atgccggatt ggatgtcgaa tcttttgaac atgaaattga tcgtctactg gatgagtatc
    28441 cagttgtttc tggtggaaac gtccaatatg gacaaaacct cagccagaat ttctttcgat
    28501 tattgaatga agcagaccaa atacgtgaaa gcttcggcga cgagtttctt tcaacggaag
    28561 tcgttatttt agcgttgatg aaattaaaaa attatccgtt aactgtttat ttgaataaaa
    28621 acggattatc tgaaaaagaa ttgcgtaaaa acatcgaaga gatgagagga ggagaaagag
    28681 tgacctcaca aaaccaagaa gaacaataca aagcattaga aaaatacggc gttgatttag
    28741 tacagcaagt caaaagcgga aaaatggatc caatcatcgg tcgtgatgaa gaaatccgtg
    28801 atgtcatccg tattctttca cgaaaaacaa aaaataatcc tgttctgata ggagaacccg
    28861 gtgtagggaa aacggcaatc gttgaagggc ttgctcaacg tatcgtacgc aaagatgtgc
    28921 ctgaaaattt aaaagataaa acgatttttt cattagatat gggtgcattg atcgctggag
    28981 caaaattccg tggtgaattt gaagaaagac taaaagcagt cttgaaagaa gtcaaaaaaa
    29041 gtgatggacg tatcctcttg ttcatcgatg aaatccacaa tatcgtaggg gcaggaaaaa
    29101 cagaaggaag tatggatgcc ggaaatctgt tgaaaccaat gcttgctcgc ggtgaattac
    29161 atttgatcgg tgccacaact ttagatgagt accgtcaata tatggaaaaa gacaaagcgt
    29221 tggaacgtcg ctttcaaaag gtattagtca aagaaccaac agtggaagat acgatcagta
    29281 ttctgcgtgg attaaaagaa cgttttgaga tccaccatgg tgttaacatc catgacaacg
    29341 cattagtagc agcagctact ttatctgacc gttatattac tgatcggttc ttaccggaca
    29401 aagcaatcga tttgatcgat gaagccagtg caacgattcg ggtagaaatg aactctatgc
    29461 caacggaatt agatcaagtt actagacgtt tgatgcagtt ggaaatcgaa gaagctgcac
    29521 tgaaaaaaga atcagatgat gcaagtaaaa aacgcttgaa aaatttgcaa gaagaattag
    29581 ctgaacttcg tgaagaagca aatgcgatga agatgcagtg ggaaacagaa aaagaagaag
    29641 tcaattctgt ttcagcaaaa cgtgctgaaa tcgataaagc aaaacacgaa ttagaagatg
    29701 cagaaaataa ctatgattta gaacgcgctg ctgtattgcg tcatggtacg atacctcaat
    29761 tagaaaaaga attgaaggaa ttagaagcta aagcaaaaga cagcgagatt aagatggttc
    29821 aagagtccgt taccgaaaat gagattgctc aagtcgttgg cagattaacg ggtatccccg
    29881 taacgaaact tgtagaaggt gaacgagaaa aactaattaa attgaatgaa acacttcata
    29941 aacgagtgat tggtcaagat gaagcagttg atgcggtcag tgacgcggta attcgttcac
    30001 gggctggatt gcaagaccca aatcgtcctc taggttcttt ccttttccta ggaccaactg
    30061 gtgtcggaaa aaccgaatta gcgaaagcgt tagctgagaa cttgtttgac tcagaagatc
    30121 atatggtacg gatcgatatg agtgaatata tggaaaaaca tgctgtgtct cgtctagtcg
    30181 gagctcctcc aggctatgta ggttacgaag aaggtggtca attaacggaa gctgtcagac
    30241 gaaatcctta tacaatcgtc ttgttggatg aaatcgaaaa agcgcatccc gatgtcttca
    30301 atatcttgtt acaagtccta gatgacggac gcttgactga ttcaaaaggg cgagtagtag
    30361 atttcaaaaa tacggttctg atcatgacca gcaatatcgg ttcacagtta ctgctggaag
    30421 gcgtgactgc tgatggaacg attccagaag cagtggctga acaagtcaac acgctattac
    30481 gtggaaactt caaaccagaa ttcttgaacc gaatcgacga cacgatttta tttacaccat
    30541 tgagcctaga caacgtgaaa ggaatcgttg acaaaatggt ggcgcaattg gcacaacgtc
    30601 tggaacatca agaaatcctg ctgacaatca gtgatgaagc caaaacgtgg attgctgaaa
    30661 atgcttatga accagcatat ggtgcaagac cattgaaacg atttatcact aaggaagtag
    30721 aaacaccact agctaaagaa atcgttgcag gacatgttat gcctaaatca aaagtaacga
    30781 ttactttact tgatggacaa cttcatttca aaacagaaga gctagaagaa atcgtctaat
    30841 cttccattga gactataaaa gaaaaaaggg gtctgacaca actagtgtca gacctccttt
    30901 tttcaaataa acagtgttcc agaagtagtt tcttcgaaaa ataagccgaa atttcttgaa
    30961 gctgcccgct tctgtcacaa cctcttttat taggtatttt tcactttttc taatttataa
    31021 ctttcaaagt aacgctcatc ttttttactt tgagaccatg caaacaatcc cattaaggca
    31081 gcacctatcg tatttgtcag caagtcgccc atcgtatcca tcaatgctgc tcgtccgaca
    31141 aacagtgtgc catcagaagc agcaaaacgt tgaagattca tgcctaagaa ctggtcgcat
    31201 aagaattccc agaactccca aaacacgccg caaagtccag caaacgcaaa gccgaataag
    31261 aggaacaacc aaggactggt ttttgatatc tcagcatctt tcatcaagta accaatcaat
    31321 ccatagccaa gagctgtcag gaccattgga ctcaccgcat gtaagatttt gtcccaaaaa
    31381 gagatgatac tgatcaaatg catccctgtg cctaaaaaga cagagatgaa caagaaaaac
    31441 cagtaaaaca aaacgattgc tgctggtatt ttaagtttga aaactttcaa aatgacttgt
    31501 ggcatgaaaa tcaatgcaat ccctaataaa gattccacga taaatgtgat tccttgagaa
    31561 gtcgaatatt tttgtgtgat aaattcataa aaattatagc agacaacgaa tacaccaaaa
    31621 gcaagtaaag ctatttgcac ctttttgatt tctttaatca ctgaaagtcc ctccatctaa
    31681 aaatcttttt acttctgaaa gcaactcaat ttctgaagaa accacttttc cgttcaattt
    31741 gatcaaacct attgtatata agttcaggta gtgaaattga ttttcagctg tttcttgtag
    31801 tgcagcgatt tttttcgggt gggttccgcc ttgctgtcga gtatcagtat ataagccgat
    31861 cactgggatg cctttcgcat aagccacacc gatttccgat gctaccccgg catcgatcgt
    31921 cagcccatct agtaaagcaa tcattaaatc actagccaac actttttctg tgtcagcaag
    31981 agcaatcatt cgactgtctg cataagcagt tttgtcattg attgcttcat tttcttgagg
    32041 aagatagatc gaaagctcag aagagagctc tctgatttct ttaactaact gttggttata
    32101 taacaaatca cttttagcaa acattggtgc ggcaaaataa attttcatct aaacatcatc
    32161 ctttttatca aaaataatcg ctaaagtaag cttccatgtt tggaatgata cgctctagtg
    32221 acttcagtgt ttcttcatct gtttctaacc gttcgattct tgccaaataa gaagcacggc
    32281 gataattcat catcaagcaa gtcaatgttt ggatatccag tcgaacggat tttcctatag
    32341 gttcatttaa gacacggact tgtccctgtt catcccatgt taaagcgaag acaccattat
    32401 tccaaggagc gacaggatct tcaatgatga aatgaaaagc atcagctgtt ccaacaaacg
    32461 gaaaccgttg aaggaattct tttacatcaa cgatccgagc cataaaatat ggttcgatct
    32521 gctctttgat ctgactatct tcaatcaaaa atgctaaagg ctcattttta taaatatctc
    32581 catgtaccca gtagatcatg gaaaaatgtg cggaaataaa gttccataag ccatttcgag
    32641 cttcttgatc aagatagaac atttctttta cgtgaaatat ttcttcagct acccagtaga
    32701 acagaacacc tcttggttca tggttgctat cgtagtagac agcggctgtg cgctcatctt
    32761 cattttcgaa acgccaatac tcttcccaat gaaaatcact gcggaataaa gcaccatggt
    32821 tttgttgggc aaatttgtca taaacggaaa atacgtctgg atgatcaact ggtaatcgct
    32881 caaccatacc acttactggg atttgtttag gtagctgtgt atctctgatt ttaaaggaaa
    32941 gtttatcaga catgatttcc catcctttac gccgatagta ggggatactg taaggataca
    33001 aataagagat ccattgctta ttcttgcgca tattatccaa tgcaacgata attagatctt
    33061 gcatcaatcc atggttagca tattctggat aagttccaac tccagtcaca ccacccattt
    33121 tataacgtgc accgtgaata ttgacttcac aaggatagat agcgatttga gagatcagtt
    33181 tattttcgtg gaaccatccg aacactttcg atacttccaa aatcggtttt ttggaacgga
    33241 taaaagctcg tttattctca aacccgcttt cctcgatgtc tgcttcagtc acttggaaca
    33301 cataggaaag caattcattg aattgatcga tatgttcttg agtgaccggt tttaattcaa
    33361 gattttctct aaaatctttt tgatccattt tttcatctcc atttattagc ttgataacag
    33421 tatagcaaaa ttctacaaaa aaaacttcta tagctgacta attaaaaact ctttaaatta
    33481 ctgcttttcg ttggtataat ggaaagtgct gattatatga aaagaggaga cgctatggat
    33541 ataaagaaaa tgaaagaacg ccaagagcag attcgtaatt tttcgatcat cgctcatatc
    33601 gaccatggga aatctacatt ggccgatcgt attttagaaa tgacgcacac tgtgacgtct
    33661 cgcgaaatgc aagatcagct gttagactcg atggatttgg aacgtgaacg tggaatcacg
    33721 attaaattaa atgctgtaga actcaattac acagcgaaaa atggagaaac atatatcttt
    33781 cacttgattg acaccccagg gcacgtcgac ttcacctatg aagtctctcg aagccttgct
    33841 gcctgtgagg gtgccgtttt agtggtcgat gcagcacaag gaatcgaagc acaaacattg
    33901 gccaatgttt atttagcgtt agacaatgat ttggagatcc tgccagtcat caataaaatc
    33961 gacctacccg cagcagatcc cgaacgtgtc cgtcaagaaa tcgaagacgt aatcggaatc
    34021 gatgctagtg aagctgtatt agccagtgcc aaatcaggga ttgggattga agatattctc
    34081 gagcagatcg tggaatatgt tcctgcacca agtggagact tagatgcacc gctaaaagct
    34141 ttgatctttg actctattta tgatagttac cgcggtgttg ttctaaatgt ccggatcacg
    34201 gacggtatgg tcaaacccgg agacaaaatc aaactgatga gtaatggcaa aacatttgat
    34261 gttacagagg tcggggtctt ctcgccaaaa gcagttgcta gagacttttt gatggtcggt
    34321 gatgtcggtt atatcacagc aagtatcaaa actgtccaag atacacgagt aggggataca
    34381 gtaacgttag cagacaatcc tgccgctgaa gctttaccag gttaccgaaa aatgaatccg
    34441 atggtttatt gtggtcttta tccaattgat acttctcgtt acaacgattt gcgggaagct
    34501 ttagaaaaac tgcaattgaa tgatgctgct ttacaattcg aaccagaaac ctctcaagca
    34561 ttaggttttg ggttccgctg tggattcctc ggacttcttc atatggatgt cgtccaagaa
    34621 cgcttggaac gggaattcaa tctagaattg atcacgactg caccatccgt tatttaccat
    34681 gttaataaaa cggatggtac gactgctaca gtagataacc cggcagattt tcctgaacct
    34741 gtaacgattc aggatgtaga agaaccattc gtcaaagcac agatcatggt cccaaatgat
    34801 tttgtcggtg cagtaatgga actttctcaa cgaaaacggg gagaattcat tacgatggat
    34861 tatttagatg attaccgagt aaatgtcgtc tataatattc cgctttctga aattgtcttt
    34921 gactttttcg acaaattgaa atcaagcacg aaaggctatg cctcattgga ttatgaaatg
    34981 tctggttatc aaaaaagcaa gttagtgaag atggacatct tgctgaatgg agaaaaagtc
    35041 gatgcattaa gctttatcgt tcaccgagac tttgcctatg aacgtggaaa agcaatcgtt
    35101 gaaaaactga aaaaactaat cccacgccaa caatttgagg tgccaatcca agcagctatt
    35161 ggacaaaaaa tcgttgcccg ttcagacatc aaagccttgc gtaaaaacgt cttggctaaa
    35221 tgttatggtg gagatgtttc tcgtaaacgt aaactcttag agaaacaaaa agaagggaag
    35281 aagcggatga aacaaatcgg ctccgtcgaa gttccgcaag aagccttcat ggccgttctg
    35341 aaaatggatg agcaagatag tgtgaaataa cttataatca atcgaaaaac ctattaaata
    35401 aacctttttg agtagatgca acactgagga ttatctgtat aaaagatttt aaactgtcat
    35461 ttggttatca cggcgatact aaaattaaca aaattggaat atttttcttg aagattttta
    35521 gctgtcagta tatgatgaaa gcatctcata ggaggtgctt ttttcatggt tgataattca
    35581 agtggaaggg ttcttaaatc tctaagaaaa gagaaaaaac tatctcaaaa aaagttagct
    35641 gatttagcag gtatttcaca aagtacttta gttaaatatg aaaaagggtc aagaaaaatc
    35701 cctaaagacg tagataatac tctaagcaag attctgaata tagaaactct aataaaagat
    35761 gaggaagata agattgagat tctcatcggt aaactaattg catacagaga tatgaataag
    35821 ttacttaaca aagagttagc tgataatata ggaattagtg aagtattact cagttatgtg
    35881 ttaaatagaa agagaaatcc gtcaaaagaa atgcaaaaaa aaatcgatat ttttctatta
    35941 agtaatgaaa aag
//
LOCUS       DAFKHN010000023        34967 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFKHN010000023 DAFKHN010000000
VERSION     DAFKHN010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.023"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            164..1027
                     /locus_tag="LY912_001130"
     CDS             164..1027
                     /locus_tag="LY912_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBM6954840.1"
                     /translation="MLMSIRFVDFGYKISHSIIGLAIVMFSLLVAPYVQLIKWSVMGM
                     LIHFILLSSILMATASDPKMGNASLYGFSYLFIVYSLPKDSLNKNFFTQTSSLLFLFF
                     CWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQEKIWMLIYAFGISLLIVAGEYVPFQR
                     LMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGSLIGCVLFIGISQFIPFNWVGILGGL
                     ALGVCSTYRYKTVFNSFGALAITASLFGVPGAVTIRIFENILGVCLGIMYIGVTEILI
                     RKIREKHGLNH"
     gene            complement(1105..1398)
                     /locus_tag="LY912_001131"
     CDS             complement(1105..1398)
                     /locus_tag="LY912_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBM6954841.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            1566..1880
                     /locus_tag="LY912_001132"
     CDS             1566..1880
                     /locus_tag="LY912_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBM6954842.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            1901..3880
                     /locus_tag="LY912_001133"
     CDS             1901..3880
                     /locus_tag="LY912_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBM6954843.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            3893..4219
                     /locus_tag="LY912_001134"
     CDS             3893..4219
                     /locus_tag="LY912_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBM6954844.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            4235..4753
                     /locus_tag="LY912_001135"
     CDS             4235..4753
                     /locus_tag="LY912_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954845.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            4753..6105
                     /gene="celB"
                     /locus_tag="LY912_001136"
     CDS             4753..6105
                     /gene="celB"
                     /locus_tag="LY912_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBM6954846.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(6189..7694)
                     /locus_tag="LY912_001137"
     CDS             complement(6189..7694)
                     /locus_tag="LY912_001137"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBM6954847.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(7786..8376)
                     /locus_tag="LY912_001138"
     CDS             complement(7786..8376)
                     /locus_tag="LY912_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBM6954848.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            8555..10201
                     /locus_tag="LY912_001139"
     CDS             8555..10201
                     /locus_tag="LY912_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBM6954849.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            10250..10969
                     /locus_tag="LY912_001140"
     CDS             10250..10969
                     /locus_tag="LY912_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBM6954850.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            11448..12395
                     /locus_tag="LY912_001141"
     CDS             11448..12395
                     /locus_tag="LY912_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6954851.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            12407..13327
                     /locus_tag="LY912_001142"
     CDS             12407..13327
                     /locus_tag="LY912_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6954852.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            13368..14825
                     /locus_tag="LY912_001143"
     CDS             13368..14825
                     /locus_tag="LY912_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6954853.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            15170..15784
                     /locus_tag="LY912_001144"
     CDS             15170..15784
                     /locus_tag="LY912_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBM6954854.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            15777..17501
                     /locus_tag="LY912_001145"
     CDS             15777..17501
                     /locus_tag="LY912_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBM6954855.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            17498..18949
                     /locus_tag="LY912_001146"
     CDS             17498..18949
                     /locus_tag="LY912_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6954856.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(19422..21575)
                     /locus_tag="LY912_001147"
     CDS             complement(19422..21575)
                     /locus_tag="LY912_001147"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBM6954857.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(21577..22623)
                     /locus_tag="LY912_001148"
     CDS             complement(21577..22623)
                     /locus_tag="LY912_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6954858.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            22773..24062
                     /locus_tag="LY912_001149"
     CDS             22773..24062
                     /locus_tag="LY912_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBM6954859.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            24075..26777
                     /locus_tag="LY912_001150"
     CDS             24075..26777
                     /locus_tag="LY912_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBM6954860.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            26762..27619
                     /locus_tag="LY912_001151"
     CDS             26762..27619
                     /locus_tag="LY912_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBM6954861.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(27690..28589)
                     /locus_tag="LY912_001152"
     CDS             complement(27690..28589)
                     /locus_tag="LY912_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBM6954862.1"
                     /translation="MVQLVCNCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            28758..30929
                     /locus_tag="LY912_001153"
     CDS             28758..30929
                     /locus_tag="LY912_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBM6954863.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            30997..31338
                     /locus_tag="LY912_001154"
     CDS             30997..31338
                     /locus_tag="LY912_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBM6954864.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(31614..33368)
                     /locus_tag="LY912_001155"
     CDS             complement(31614..33368)
                     /locus_tag="LY912_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954865.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(33379..34215)
                     /locus_tag="LY912_001156"
     CDS             complement(33379..34215)
                     /locus_tag="LY912_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBM6954866.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(34217..34900)
                     /locus_tag="LY912_001157"
     CDS             complement(34217..34900)
                     /locus_tag="LY912_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBM6954867.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11240 a         6164 c         7164 g        10399 t
ORIGIN      
        1 acaaaaaata cgagaagcag cttctaaaaa agaaaagtgc atgtatattt gttcattgtt
       61 tttacgatca ttattcatcg tattgtttgc catttgtttt atcattataa ttacaacatt
      121 atttgaatcg aagcataaac catacgctgt ggttttattc tgtatgttga tgagtattcg
      181 ttttgttgac tttggttata agatttccca ttcgatcata ggtttagcaa tcgtcatgtt
      241 ctcactatta gtagcaccgt atgtccagct gatcaaatgg tcagttatgg gcatgttgat
      301 tcattttatt ttactaagca gcatattaat ggcaaccgct agtgatccca aaatggggaa
      361 tgcttctttg tacggctttt catatctctt tattgtttat tcgttaccta aagattcgtt
      421 gaacaagaat ttctttacac aaacaagtag cttattattt ttgttttttt gttggttttc
      481 agttcttctt tacagaaaac atcgagaaaa gaacaaagac aaaagcttgt ttaaagagat
      541 ttttttgaaa ggcatgtatt cgcaggaaaa aatttggatg ctcatctatg catttggcat
      601 tagtcttttg atcgttgcag gagagtatgt cccttttcag cgattgatgt gggcagggtt
      661 tgcattttct tctattgtat ctagctatgg attgatgtcg attggtttca aagaacgagc
      721 agtagaccga atcattggct cattgattgg atgtgtttta tttattggta tcagccaatt
      781 tattcctttt aactgggtcg gtatattagg tggtctagct ttaggtgttt gttctaccta
      841 tagatataaa acagttttta attcttttgg tgctttggca atcactgcca gtttattcgg
      901 ggttccagga gcagtaacga tccgcatttt tgagaatatc cttggggtat gtttaggaat
      961 catgtatatt ggggtgactg aaatacttat ccgaaaaata agagaaaaac acggtttgaa
     1021 tcattagatg agatcgaata aaaaataagg aaaaagtgaa gatacacatg gatgataaat
     1081 tgctatcatt ccatgtgtat ctttttacgg taaatcagtg aaacgttcga ctttcatttt
     1141 taatttatac tttttacgga gttcgtttat ttgagccatc atttcggatt tgtgatgctt
     1201 ttcgattgct tcttcatctt tccaacggtc gatcagtaaa agagattctg gatcttctag
     1261 tggaaagtaa tagtcatatt tctcgtttcc ttcttctgca cgaatcgctt tgacaatgtt
     1321 tctttcgacc atttcttctg caaattttct ggcttgtcca tttgtacttg tatacaaaat
     1381 attcactgtg atactcacta aatcccctcc tgaaaaaatt ctatcactag tatatcacgg
     1441 tgccagaaat tattattcaa gatatgatac acattttttc cgcaatgcta cggaaatata
     1501 tattttgaat agaaaacgct tacaagatat gcttggttta taaaaataaa aggagtgatt
     1561 gatttatgaa aaaagcattg attatttgtg cggcaggaat gtcatcctcg atgatggcct
     1621 caaagacaac ggatttcttt aagcaaaaaa gagaagaggt actcgtagat gcagtttcag
     1681 ctacagaagg cgataatatg attaagaata gtgattttga tttatttctg atcagcccgc
     1741 aaacgacgat gtttttggat aaattcaaaa aattaggaga atctgttgga aagcctgttg
     1801 ttagtatccc tttccaagcg tatgtcccaa tccctacagg catccagaag ttagcagagg
     1861 tgatcgaaga gaacatatga tggaatagga gtggatgata atgaaacaga aggaaaaatt
     1921 gctgttgaga tatttgattg atcacaagaa ggagtatgtc accagtcaac gtttagcttc
     1981 tgaattgtta ttatctgatc ggacaatccg taattacttg cagcggatca aagagttagt
     2041 agaaaaaaac ggaggtaaga tcattgctaa accaggttat ggctaccaac tgcatatttt
     2101 acaaagactg acatttgact tgtttttgag tcggcaagaa atagtacctg gatatgctag
     2161 agaaccgcaa ggattttatg agtccgaaga tcgacaaaag tatatattga accaattgct
     2221 tttggaagat gccattcttt ttatggatga tttggcagaa gagctttata tcagtcgttc
     2281 cagtttgaca aaggacatgc aagaaatcaa ggagcgattg attccatatt cactaaaaat
     2341 cgtttctaag catggtcaag ggacatggat cgaaggggaa gaaagaaatc gacggcattt
     2401 tatcatggat actttttttg gaaaccatta tggaaattca ttgaaagaat atttagggca
     2461 aagccgtttt ttcccagaca tcagttttga agagctagtc attatcattc tcgatgaaac
     2521 aagagaagct aagttaaaag tttcggattt tatcatacag aatctgactt tacacttggc
     2581 tttggggatc aaacggctcc gagaagggtt tgaaatcaag gaattaggca tcgaacaaga
     2641 agtttctaag cgagtagagt atcaagtggc gcagcggatc gttcaacgta ttgaggtaat
     2701 cgcaggtgta tcgtttcccg aagaagaaat tgcttatttg acattacatc tcatggctaa
     2761 gtcgaatcac aaagaaaatc aaaatgatca ggaactatca aaggaattag cgaaagttct
     2821 gaaaagattg tctcaggaat ttcatttttc attagtagag gatctccagc ttttcaatgg
     2881 actactcgat catttgtcac cgatgatgat tcgattgagc cgaggtattc gcattgagaa
     2941 cccattgact gaggagataa agaaagaaaa tcccaaagtc tttgacgcag taaaaaggca
     3001 tttcagcaac atgccggctt tgaaaaacta taccatcaat gaagatgaat gggcctattt
     3061 ggctttgcat ctcatggcgg cattggaaaa agaaagagct gcgcataaac tacatgcatt
     3121 gattatctgt gcaacgggtt acggcagtgc ccaactatta aagaatcgcg tagtcagtga
     3181 attcggtaaa aatattacag tggtaagtgt aaaaggctat tatgagatca atgaaacaac
     3241 tttaaaagga atcgacctga ttatttcttc tattgatctt tcgacaatgt ttttcaaaat
     3301 tccagtttta catgtcagta tttttttgaa tgaagatgat gttcgtaaaa tacgaaaggt
     3361 agttggagaa tctataccct atcattcctc agatagaccg ataccagcat tttctctaca
     3421 gcaaaaaaag cagatttaca ccgaacagtt gtctgaaaaa tttttcaaga cttatacgta
     3481 cgaaccgaaa aaggaagaaa ttcttcatga tttgctgcaa aagctgagca taaatgaaga
     3541 agaaggatat ataagagaaa tgcgaaagca gatccagcaa cgtgaaaata tgggacaaat
     3601 catattcagt gatacagtgg cagtcccaca tcccgctgtt ccagttggaa tcgaaacaaa
     3661 ggtagccgtt gcattgattc cttctgggat gcagtgggat caatatcaag aaattcattt
     3721 tgttttttta gtttcgcctt cttatgtcga aaatgaagga attacggtcg tgactaaagc
     3781 aatcgttagg ttagttgacc agctaaaagt acagcaggaa atcttagctg aacctatttt
     3841 tgagaatttc agcagtaaat ttatcaaact gatcgaataa ggaggaaaac agatggctga
     3901 aaaaataaac agtgaaacac tacaagtgac ttcttttgat atcattttcc atagcggaaa
     3961 tgcacggaca ctgatacatg aagcatttcg ctcgatgcgt aaagagatgt ttgaagaagt
     4021 agaagagaag ttgcgacaag caaatgaaga gattcttcat gcgcatcagt cacaaactca
     4081 acttctgaaa gaatatgcca gcgggacaaa aatagaaatg gaaattatca tggtccatgc
     4141 acaagatcat ctgatgacga cgatgacatt attggaagtt gcacaggaaa tgaattattt
     4201 gtatcaaaaa aataaataga aaggaaggat cattgtgcag gatacagtaa aaaggaaaat
     4261 cgaattagaa aaaaagcaac ttagtttgaa aaacatgtat ttcaatcgtt atctaatcgt
     4321 acgttacctg actgcctttt tctttttcat gaacatgcaa tggatgattc tgcttctatc
     4381 agctaaaagt ttaggaagta gtttaccgat gattctgatt ttagctattt tgcctgcagt
     4441 aggagaacaa gtaaagcttt atcgaaaaca ccaaacgaac gttccatgga caaagtggta
     4501 ttttttgttc cagagtgtct ttaatttatt agtgattcca gtgttgttta cctcaggatt
     4561 tacattcttg tatcctttta tggcaaataa caatggagga cagttatttg ttttcattct
     4621 tgttgtaagc ggtatttttg ccagtgcatt tatacagtat cgtttaaaga aaatttcact
     4681 caaccaagac caacagtata tccgtattaa acaatatgaa aaagcgttat atttaggaaa
     4741 ggagaataac taatgtttga ttttttgcag aaatacctga tgggacctat ggggaaaatt
     4801 gcgcaactta aaatcgttcg ggctgtcatg gcagcgggga tggcttctat tcctttcacg
     4861 attgtaggct cgatgttttt ggttttaaat attttgccat taccgttccc atttttagaa
     4921 ggatttttta atgcaacttt tttcaaagtt agtgacttgt acatgatcgt caatacaatg
     4981 acgatgggga ttttatctat ttactttgcc attgtgtttg cttatgaatt aacgtcaatt
     5041 gaacgagatg aacaaaaatt aaatgttaat ccgctcacgg gggcattact atctgttttt
     5101 gcattcttta tgtgtatccc tgaattgatc atgactgatg gtaaaatcag cttgattgct
     5161 tctatcaatg agacagaaac tgtagtaaat ggtattagga tgggctcttt tgtcgaacgt
     5221 ttaggaactt caggaatctt tacagctatt attatgtcga ttattgcggt cgaattgtat
     5281 tgtatgtgtg tcaagagaaa ttgggtcata aaaatgccag atgttgttcc gccaggagtt
     5341 tctcgttctt tcactgctct gatcccaaca tttgtcattg cgtttgtggt gatgatcatc
     5401 aatggattat tagttgcact aggaacggat atcttcaaaa tgattgctat cccatttggg
     5461 tttgttacgc agttgacgaa tacatggctt ggtgtcatgg tgatttattt cttgatccat
     5521 gcattgtgga tcgtagggat ccatggagcg aatatcatca cttctttctt gaccccgatc
     5581 gtattagcta atatggcagc taacgcacaa ggcgcaaatt atccgttggc aggagaattc
     5641 aacaattctt atgtaaccgt tggtggatca ggtgcgactt taggattgat catctttatt
     5701 gcattcctcg cgaaatctga tcagctgaaa gtgttaggaa aagcctcact tgtaccagga
     5761 ttattcaata tcaatgaacc aatcattttc gggatgccaa tcgtctacaa tccctattta
     5821 gcggttccgt ttttcttagc tccgatggct tctgctacac tcgcttattt tgccattcgg
     5881 ctggaaatcg tcaaaccgat gcttgcacag atgccgtggc cttcaccagt cgggatcgga
     5941 gcatttgttg gtagtggtgg tgattggaaa gctgctgtgt tagcagtcat ttgtgcaatc
     6001 atcgcattca ttatctggtt cccatttatc aaattctatg ataataaatt attaaatgaa
     6061 gaaagagaaa aggcagcaga attagctagt gaaaagttaa aatgatttct aagaaaaaag
     6121 gaactgtgac aaaaaatcac agtccctttt tttcttagaa atgggaaacc actagtatat
     6181 aaataccatt attcttcaat caaccgcttc acgattgcat aatccccttc ataaggttca
     6241 tctacaccat tgattttttg atagggatcc acgccttttc ccgcaataac gactgaatct
     6301 tgcggagcgc tttctgctaa agcgcgtcga atcgcttcag gacgatccat ttcataatga
     6361 acgatcaaat ctggattagt aattgcttca ttgatttctt ccgcgatttt tttcggatct
     6421 tcaaatgctg ggtcatctgc cgtcaaaaag gcgatgtcag ctgtttctga tagcactttt
     6481 ccaaaatcat gtcgacggga gattgctttg tttcctgggc tgcctaatac aacaattaca
     6541 cggccatctg gatgttcatt tttggcaaat tccagcaatg ttttcaagct tagataatta
     6601 tgtgcatagt ccacatagac atgcgctcca ttggattgga tcaattgatc cattcggcct
     6661 ggtacacgag cttcttttaa tccgtcttgt gcatcttgac tggaggcacc tgttagtgct
     6721 gcggcaatga tcgcactggc tgcattttct tggttgaatc ctccagccag caaaatatca
     6781 taagcagtat cgcagatagc taagcgatct tcatgagaag ataaagtaaa accgtgagta
     6841 cctttatctg aacggatcac ttgataattg ctttcttccg aacgaccata agtgatcgtt
     6901 ggaatctgga atagatcggc tgtttcccta agtaaatcaa aatagtcact ttcatgattt
     6961 aaaacaactg tttttgaatt caagatcaat tgtcgcttgc aatagaaata gtcatcaaat
     7021 gtcggatgtt cgatcggact gatatggtca ggcgagatat tcaagaagat tccgacatct
     7081 aaagtcaagc cgtatacgcg ttgtgttttg taagcttgtg aagaaacttc catcactaga
     7141 tgagtcatac cattttcaac tgcttctgac atcatacgat ataaatctaa tgactcaggc
     7201 gttgtcaaat gggatttgaa atatgttttg ccatctaacg ttgtattcat agtagaaagc
     7261 aatgctgttt ttttatttgt tgtgtgatcc aagattgctt ttgtaaagta cgcagcagtt
     7321 gttttacctt ttgttccagt gaatccgatc actttcaatt tattttgcgg atagtcgtaa
     7381 aaagccatag caagaagcgc cattgcttta cggatatccg ttacgatgat tcctactgct
     7441 gaattttcgt atggttgttc tgatacataa tattgaatac cctgttcgat tgctgaatcc
     7501 aaatattctt ctttgaaatt cattccttta cagaaaaaca aagtagaagc atcagctttt
     7561 cttgaatcat aacttaactg aagaaattca gctttttctg gtacatcaag atgccagcct
     7621 cttgttgaaa caaattcttt taatagattt tcttttaata gtaaatgacg gatgtcttct
     7681 aaagagaagc tcattgattg atccctcgct ttattcaatt tcttggttta ttatagcaca
     7741 ctctttttaa tatatcgttt gtttccgcta tgacaaaatc cagctttatt caaattttct
     7801 tgacacaggg gacaagcgga tgagtatttt cataaacaat gaactgactg taatagatag
     7861 gagaacgaat agtgtctcca acaatccaaa aacataataa ttcaaaaaga cgataagact
     7921 attggtaagt aaaagtcctt gcggcattgg aagccgaaaa aatttgtgga aaataatcgg
     7981 cggtatcgtt ataccgccat ttgaggcccc gactgtgtac aatgtgtaaa ccccaagact
     8041 gaacaaaaga cttcctgaaa tcagtgaaaa gaaatgtgag gagatcattt ccacttttgg
     8101 aacaatctct aaaacaacag gaaaaagcag acttcccgct acagtcttaa aaaatactga
     8161 ttttcctaat aggacagcgg ctagaagcag catcataaga ttgatgctcc aaacagtaac
     8221 tgagcgttgg atagaaaagg ccgtttcaac taaatgtccg atggcgccca ctccggcgga
     8281 agctatatcg tgagggagca agaaccaatt caatccaact gtgataaaga aaagacctaa
     8341 aaatataacg ggtagttttt ttatttcttg tgtcattgat atctcctata aatgttagcc
     8401 ataaaaggct gtatatttct ttactttacc aaaaaaacga aaccgaattc aaaaaaacaa
     8461 ttgttcttat aaaagttata taaaatcgat tgccagtttc tgttttacca attaaaatga
     8521 tagtaatgtt ttgtagaaag ttggaatctg accgatggat aatcaaagaa aaccagcatt
     8581 agatcaatta acaccgcaag aaaaaatggc acgaggctct gcttggatga ccgccagtaa
     8641 tatcatttca agattgctag gcgctgtcta tatcattccc tggtatgctt ggatgggcga
     8701 aaatgctaag gctgccaatg gattattcaa tatgggatac aatatatatg cattgtttct
     8761 actgatctct acagcaggaa tacctgctgc gattgcaaaa caaactgcac gctataattc
     8821 attgaatgaa tatggcactt cacgacgatt atttatccgt gcattacaga tgatgggcgg
     8881 gctaggcctg ttgtttgctt tgttcatgta catcgcctct ccttggctag ctcatgcttc
     8941 tggtggcgga gaagaactga ttccaacgat gcgttctttg agtatcgctg tattggtttt
     9001 tccttgtatg agtgtgatac gagggtattt tcaaggcaat caagaaatga tgccttatgc
     9061 gctgtcgcag attgtagaac aggtggcacg tattttttat atgctattgg ctacattcat
     9121 catcatgaaa gtcatggatg gtgactatgt gacggcggtc acgcaatcaa ctttcgcggc
     9181 atttatcggt atgctagcaa gtattcttgt ccttttgtat tttttgaaga aacatcaagc
     9241 gtatacatcg gcgtttattc actacagcga aaacaaaata aatattgcaa cgaaggaatt
     9301 gttgttagat accgttaaag aagcgattcc gtttattatt gtgggttcag gggtaacgat
     9361 cttcaaatta gtcgatcagt tcacttttat gaagatcatg tctgcatcca ccgagtattc
     9421 caatgcacag ttactggatc ttttttcgat ttttagtgcc aatccagata agttgacgat
     9481 ggtagttatt gcattggcaa catcgatcgc gtctactggg ttaccgttga ttacagaagc
     9541 tgttacgttg aaagatcgag taggtctggc aaaattgaca agcggaaatt tacagttgtt
     9601 ttcatttttt atgtttccgg cgacatttgg tgttatgtta cttgcctatc cgctaaatac
     9661 attattttat acaccggatt ctctaggaag taatgtactg atccaagcaa gttttgtagg
     9721 actcttccta ggactatata tgctagtttc caacatgctg caaggaatgt ttgaaaacaa
     9781 ggcggcaatt aattatttgg ttattgggtt tctagtgaaa ctccttcttc aatacccagc
     9841 cattcgttta tttgaagtat acggcccttt attggcgaca atgatcggat ttgctgtgtc
     9901 ttgtaccttg atcttaaaga gaatccatga agtagcccgc tttaaaccaa gttttgtctg
     9961 gcgcaggaca ttgctgatct ttattcttac cttgattatg cttttggctt cgtggatcac
    10021 aaagatgatt tttggtgctt ttttaaacga agatagcaaa ttccagtctc tattgttgat
    10081 tcttgtagta gcaggtatag gggctttagt gtatggttat ttagctttga aaatccgctt
    10141 ggcagaaaga ctactaggac caggaatagc gcgtttacga cataaattaa aaataaaata
    10201 agtgaatcag aagagctaga ttgatgctct tttgaaatgg gggaaacgca tgcgtttaga
    10261 taagttttta gcagatatgg gacttggcag ccgcaaagaa gtcaaaggat tgatcaaaaa
    10321 aggaacgatc gaagtcaatg gacaagtggt gaaaagcgat aaagcgcaag taaatgaatt
    10381 cgaagatgcg gttacttatt taggagaaat cattacgtat caaaaagatt tttactacat
    10441 tttgcataaa cctgcaggag tcatttctgc tactcaggat aatcatgatc aaaccgtaat
    10501 cgatttattg gaagaccagg attatcggga agatcttttt ccagtcggcc gattagataa
    10561 agacacagag ggcctcttga ttttaacgaa tgacggggtg tttgcccatc agttactatc
    10621 acctaaaaaa catgtggaga aagaatatct agctgaggtt agcggtataa tgacagaaga
    10681 agatatccgt ttatttgcag aaggactgat tattgatggc gatgagcaga cattgccggc
    10741 aaaactccaa attgatcaag tagatcaaga gacagaaact tcaattatcc gtctgatttt
    10801 gcatgaagga aagtttcacc aagttaagcg aatggtcaaa gcagtaggaa aagaagtctt
    10861 atatttaaaa agaatccgta tgggaaaatt ttggctgcct aaagatttga ataaagggca
    10921 atatcgaccc atgaccaaag aagagctaga acaagtgaga gaaaaataat tgaatggata
    10981 gctaaaagaa taagcagagt agttgtagcg ccatctgaaa agcagacttg tccgtctgac
    11041 tttcggatgg cttttttgtg aaatttcggc ttatttccgt agaagctact tctggaacac
    11101 cgtttgttcg gaataaggga ctgtgacaag acttttgtta cagtccccat tgttccttgt
    11161 gactcagagt tagatagtaa ggacacgatc tccctaatac tcaggccaaa acgctgaatt
    11221 cacaacctct gataaacggt gttcaatcag ctgaccctcg gtattagctc aaaaaacggc
    11281 aaaatatgag gaactatttt cccgtttttt tctctaatac tcaggccaaa acgctgattt
    11341 cacaacctct cctatacttt gtttcatttt ccctatactt tgtttattta ttctcattat
    11401 tgaaagcgct ataattacgt tgcgaatgaa tcgaaagggg tttttagatg aaaaaacgaa
    11461 aggggttcaa tcattttttt atgaatctat ggcgttataa agcacttgtc ctgatggctg
    11521 taccgggtat gctttggatg atttttttct tttacatacc tgtaatggcg aatgtcgtag
    11581 cattcaaaaa ttttcatatt tcagcagatg ggttcttggc tagcttgagg gaaagtcctt
    11641 gggtgggttg ggaaaatttc aaatttttat tttcttcgga tcaagcattt ctcatcacta
    11701 aaaatacaat tttatataat gtagcattta tccttttgaa tctgctgatc tcagtcgtat
    11761 ttgcaatcat tatgagcgag ttgagaaata aacgactcgt taaagtttat caaacgatgt
    11821 ccttactacc ttattttcta tcttgggtca ttatcagtta ctttgtttac gcttttttaa
    11881 gtcctgacaa aggaatattc aatcagtgga tcactggaca tggaggagaa gctgtcaatt
    11941 ggtataatga accgaaatat tggccgttta tcttggtgtt cattggtaca tggaaaggga
    12001 ttggttataa cagcattatt tactttgcat ctgttatggg aatcgatccg acttattatg
    12061 aagctgctat ggttgatgga gctagcaaat ggcagcagat caaacatgtg acgataccac
    12121 aacttattcc actaatgacg attttaacga ttttagccgt aggaaacatt ttccgagctg
    12181 attttggcct gttttataac attcctagga attccggtgc attatatgat gtgactcaag
    12241 ttttggatac gtatatctac aatggcctga catccacagg agattttggt atgacggctg
    12301 ctgcaggact ttaccaatca gttgtcggct ttgtcttgtt gatgatcaca aatacgatcg
    12361 cccgacgttt tgatagcgat tctgcattat tctaaggagg aaaaaaatga aaaaaaagaa
    12421 agtggagaga gtccaagtcc gctctttcaa taagacggct aattttttct ctaatataat
    12481 gattgcactc tttgctattt cctgtatttt gccatttata tttgttatcg ccatctcttt
    12541 taccgatgag tccatattgt cgactcacgg gtacagtttt tggccagaaa agttcagtat
    12601 atttggttat acgtacttgt tcgaccagat gcaggataaa attttccaag cgcttttcgt
    12661 cactgtactt gttactgttt taggtacact gatcaatagc acggctactt ctttatatgc
    12721 ttatgcgatt tcacggtcaa actttccatt ccgtcgtttt tttaccgttt tttgtttgat
    12781 tacgatgttg ttctcaccag ggatggtggc caattatctt gttatgacaa atcttcttca
    12841 gttaaaagat acgatttggg cattgatctt gccaatggct gtcagtccct tcaatattat
    12901 tgtgatgcgc acattcttta aacgttcggt ctctgattcg attattgaat cggcacggat
    12961 cgatggagct agcgaactgc gaatatttgt tcagatcgtt ttaccgttag ctgttccagg
    13021 tattgcgaca atcagtttat ttgccgcatt gggttactgg aatgactggt tcaatgcttt
    13081 actatacatc caagatgata agctagttcc actacagtat cttttgatga aaatccaaag
    13141 taatattcaa tatctgacac aaaattcagg agcaggaagc caattgacag gcggattagc
    13201 ctcagttcca ggagaatctg ccagaatggc gatcgtagtc atctcgacgt tgcctattgc
    13261 gatcagctat ccatttttcc agaagcattt tgtcaaaggt ctaacaatcg gcggagtaaa
    13321 agaataaaga aacaaaaata taaatcataa aattaggagg aagaaaaatg aagttatgga
    13381 agaaactagc ctttacaggt gtttcagcgt tgttgttggg aacattagca gcatgcggag
    13441 gttctggttc taaagaccag gcagaagcta gcaattcgga cactttgcag atgtatcaaa
    13501 tcggagataa accagataat ttcgatcaat tgatggaagt agcaaacaaa cgaatcgaaa
    13561 aagagatcgg tgtaaaagtc aatatcaatt acattggctg gggcgattac gaaaagaaaa
    13621 tgaacgtcat catttcttcc ggggaaaatt atgatatcgc ctttgcgaac aactatgttt
    13681 ccaatgccca aaaaggagcc tttgctgatt tgactgaatt agcgcctaag tacgctgaaa
    13741 aagcttataa tgatttagat gaagcatata ttaaaggaaa tctggtcaat ggaaaattat
    13801 atgctttccc agtcaatgga aatgtctttg ctcaacaagt acttactttt aacaaagctt
    13861 tactagataa atacgatctt tcaattgatg gaatccaatc ttacgctgat gcagaaaaag
    13921 tcttgaagga attccatgaa aaagaaccaa acacggcagc ttttgccatt ggacaaggct
    13981 tcaaagtcca agggaacttt gattatcctt tagggaatac gttaccattt gctattgatc
    14041 tggatggaga tgattcgaaa atcatcaacc aatacgataa tgaaacgtat atcggactgt
    14101 tacgtacaat gcatagctgg tacaaacaag gactcattcc aagtgacgct gcaacgagca
    14161 ataaggatta tccactagaa ggaaatactt ggctaatgcg tggagaaaca caaggaccgt
    14221 atgattatgg cgatacaatt ttgacaaatg cagcaaaaca agaacttgtc tcaaaagcaa
    14281 ttactgttcc actaaaatct acagctcaag cacaaatggc aaattttgtc gtatcaaata
    14341 cttcaaaaaa taaagaaaaa tcagtagaac ttctagggct gcttaacagt gatccagaat
    14401 tattgaatgg gcttgtttgg gggatcgagg gagaagcatg ggaaaaagtc gatggttcag
    14461 atgataaaat caaattgcta gatggttatc agccaaatac acatatgtct gcttggaata
    14521 caggaaacaa caagattcta tatacacaag agtctattac ggatgacatg attgccaaac
    14581 gtgatcaatc gattgctgat gcagaaactt caccgatttt aggattcagc ttcaacactg
    14641 acagtgtcaa aacagaatta agtaatattt ctaatgtcat gaatcaatat ttagatggat
    14701 tgaatacagg gactgttgat ccagatgaaa cattaccgaa attgaaagac gctttggaca
    14761 aggctggcta tgataaggta ttgaaagaaa tgcaaaaaca atatgatgag ttccgacaag
    14821 aataataatg aataaagaca aaggggttgt gacaaaagac gtgtcacaac ctcttgttcc
    14881 gaataaacgg tgttcaaaag ccagtttctc ggtattaagc taaatatatg taaaaatgtg
    14941 gaaagccata ttcacaaaat ttttcttact actcgaaact aagcggctat ttcacaaact
    15001 cttggtaaac ggtgttcaat cagctgaccc tcggtattcg ctcacaaaac gacaaaatat
    15061 gaggaactat ttttccgttt gtttctctaa taatcaggtc aaggtgctga ttgcccaacc
    15121 tttttttgta taatgagaaa gtataaactt aatgtttgga ggagaagata tgttagggaa
    15181 ggttttggaa gagttattta tccggatctg ggtcattata aaactaacct tgtatttctg
    15241 gatatataca tttgccggcg ggatcatctt tggattaggt gcggcatgga aaacagtcaa
    15301 tgaactattt tatttgtacg gattcgagta taaagaaatc acaataaaaa gaggctggaa
    15361 tatatataaa agaaattttt taagaggcaa tctgctattt agtttatttt tatctggtac
    15421 tgctttattg agttacaatt tatatttatc tgttcaaatc aaagggctca tttttttagc
    15481 tattgatttt attttacttt ttgccttgct ctgcctattt gctacttatc aatacagtat
    15541 gattttagat agtgaatata cgatctctgt tcctaatctg ctaaagctaa gttttatttc
    15601 ggttttttcc agcttttcgt cttttctaaa aataattatt ggtagcggta taattttagg
    15661 cgtgacttgg caattcaaag gattgatcct gtttggtgtc attggtcttt tgacggtttg
    15721 gaatggtacg atgacaacac attggcgtga agaattagat aaacagttgg aaagttatga
    15781 ataagtttcg gattctattt tcaaaaggaa ccttactaaa tcgtctgttg cggaaatacg
    15841 cggttatcat gatcggtgta acgatgactg ctaccgttat ttttagtatc catacttggg
    15901 aacaaaatca aaaacaggca gaaaacatga caagtgatgc cgttcaaagc acaagcagaa
    15961 tgctgaatga taaaacaacc ttgagtagga tcatcaaaaa ccagcttgta gggaattccg
    16021 aaaagatcga aaatgtgacg acctacttaa caaaacccat agatcagtat ctgatgtatg
    16081 tatacgaaca gcaaaacagt accgatgaat tagtttcttt cccaaatcaa atcaaagatc
    16141 tctacgcaaa ttatgaagaa ctaagtgcga tatatatcgt gttgaatcaa ctaccggagt
    16201 attatgaatc ttctagagaa aacaaaggtg gggaaataaa aaaggggaca ccaaaattac
    16261 tagacgcctt ttatatcaag ttgcctatca cacaaggagg agctgagtca ggaagtattt
    16321 ttattggttt tcaaaagaaa gaactagata tgattttaga aaatctaacg tcattcaatg
    16381 gactctcttt atacatgatt tctggaacga caaatcgact atacacattc catgataata
    16441 aaatagctaa agaaacgttt gaaagacaag aaatgatcat cacagagagt ctgaagaaaa
    16501 attcacaatt gccgattgac gatctggaaa aaaacaattt tgttcaacac caagaactgt
    16561 ctgatgatta tcgtatatta gctgtactag ataaaaaaag tgtaaaaatc gaaacgggaa
    16621 aaaatcttgc cccgctgatc attggtatca ttattttaga caatatactg cttatctttc
    16681 tttataaaac attcaaacga tattcacagc aagtatctat cgtcatgcag gccatggatc
    16741 aaacagcagc agggaattta gagacgcgga tcgacataac aaacacggaa tatgaactga
    16801 aggaactttc aatcggtatc aacgaaatgt tggatagcat caatcagttt gtagaagaca
    16861 tctacaaatt agaaatcaaa cagcaagacg cacatatgcg ggcgcttcaa gcacagatca
    16921 atccacactt tttatataat acattagaat atatccgaat gtatgcaatc agcgaaggaa
    16981 gtgaagaatt agcagatgtt gtgtatgcgt tttccgcttt gcttcgaaac aatacgaatc
    17041 aagagaaaac gatcacttta aaagaagaac tggacttttg cgaaaaatat gtctatttgt
    17101 atcaaatgcg ttatcctaat cgagtagcct atcattttat gatcgatcct gatttggaaa
    17161 agatcgaagt acctaaattt gtgatccagc cattagttga aaattatttt aaacacggta
    17221 ttgattttac tcgattcgat aatgcgctaa gtgtcaaagt cttgcaggaa ggcaaacggg
    17281 taaggatcat catcaaagat aatggaaaag ggatgactga aaaacggcta aaacagattg
    17341 aagaaaaact gtctcatcct aaagtggaac ttcacggttc tatcggtctg caaaacgtga
    17401 atgaacgttt acgtgccagc ttcggcagca gttattatat gtcgcttgag aataatgaga
    17461 caggtggact gaccgtttct attacattca aggagggatg agcgtgtatc aagtgttatt
    17521 ggtagatgat gaatacatga ttttgaatgg gttaaaaaag ataattgatt ggcaaagttt
    17581 aggctttcaa atagtagcaa cagcagagaa tgccaaagaa ggactagctg tacttgaaca
    17641 gcgacagatt gatttagtag taacggatgt gacaatgcca gaaataaatg gactggaatt
    17701 tattgaagcg gctcaaaaag aacgtcataa ttttgaattt atgattttat caggatacca
    17761 agaattcgat tatttgaaag gaggtatgca attaggcgcc gtgaattatt tgatgaaacc
    17821 cgtgaataag ttcgaattgg ttgaaagcct caagaaaatc aaaacacggt tagatcagca
    17881 aaatgaacaa aaaaatcaac aagaaatcta tcaagaactg ttattcagtc aatggttgaa
    17941 tgaagaattg gatgaaataa gtgaagaaga aataatagga caaataagtg agaagcagca
    18001 taggatagta ttgattcaac tggcaagaac tcatgatact cttatcaata gatggttgca
    18061 agaacggcaa caaatctttt actatcaacg aaattacgga gaccgtgtat tgatcacgtt
    18121 gttgttggag gcagatgaag ttgatggctt ctgttgtttt gttcaagaaa actttcctga
    18181 tcaggaatgg ctgatcagta tcggggaaga gacagattct ttggacaaaa tccctgaaac
    18241 attccaacaa gcgaaagaca atctacagtt gcatcaattt tatggagata aagacgagca
    18301 tgttttttac gcagtacaag cagaaacaaa agatcaaacc atcgattttt caagtttcag
    18361 acgcgtgctg caaaataaac aattggaagt cgctcaaaaa atgatcactg atttttttga
    18421 acagtttcag ttagcagcca tgatgccgga agatatacga tattccagtt ttttactgtt
    18481 tatggagatt caacgggaat tgattgatct ggaagatgag gaatatttac aaggaatcga
    18541 aaaaatccat caggcaaaaa cggtgcaaga acttcagcag ctacttctgt cattcatcaa
    18601 aaagcatcag agacagaaaa agtacagtga caatgtggaa aaagtaatcg taatcctgca
    18661 ccagcattat caagaaccac ttacactcaa agaagtgtca gaaaacctgc atttaaatgt
    18721 catgtatcta ggacagctgt tcaaaaaaga aacgaaaaaa agtttttcag cttatttgaa
    18781 ccatttacgt atggaaaaag cgaaacaact gcttttgcac agtaatcaaa acatcaatga
    18841 gatagcaagt gagattggct acaacaacac cacgtatttc tctaaattat tcaagaaaat
    18901 cgtcggcaga tcccctaaag agtaccgaga aaacagtgga gaatcataaa aaaaaaagcc
    18961 aatgtaatga aataacttat aaaaaattgt ctagaaatct aattttgggc tgttcttatt
    19021 acttgaggca aggcagcttt ttcatgacct ctcgataaac ggagttcaaa agccagtttc
    19081 tcggtattaa gccaaattta tgcaaaaatg tggaaagcca ttttcacaaa atttttctta
    19141 atactcgaaa ctaaacagct ttttcacgac ctctccacta aatggtgttc aatcagctga
    19201 ccctcggtat tagctcaaaa aatggcaaaa tatgaggaac tattttgcca tttgtctctc
    19261 taatactcag gtcagaacgc tgatttcaca acctctcaat aaacggtgtt caaaagcttg
    19321 catctgcggt aataagacca accaaacgaa aaatatgagg atctattttt gcttggctgt
    19381 tcttattact tgatgcagga cagctttttc acaacctctt gttaattata gtttgataag
    19441 gaaaaaggca aatcttttgc ttgatatttc ttagggtgag ggatgatccc taattggtaa
    19501 gagatcgtgc cgcctttcag caaatcttga tgggtaaaat ataatttcgt atattctctg
    19561 tccatccgtt tgattttatg gataaattgt tgctgcggcc gattaggcgt tgcttcaatc
    19621 gtcaattcct ttccatttga caaaagcaaa acagccttgt caattaatgg cataccgata
    19681 acatattcac cggttccagg cgtgacagga taaaatccca gactattgaa gatataccaa
    19741 gcggccatac ttccattgtc ctcatctcca gggtaaccca ttggagaatc gtcgaaggtc
    19801 tgagtcatca actgtttaag cagtggctgt gccatttcag gttgtcctat ataactgaac
    19861 aagtaaggat agtgaaaact tggctggttt gaaatagcta attgtccaaa ttctatcgcg
    19921 gccatctcac tcatttcgtg gatctcaaaa ccatatcctc ctgggtcaaa cgttgggggc
    19981 tgattgcaca gctcaatgag tttttcttta tatctctcac tgccaccata ttttccgatc
    20041 agtcctgaaa aatcgtgata aacagcaaag ctgctttgcc aagcacttcc ttctgcataa
    20101 tcttgtcccc aacgattagc tgaaaatggt tctctgaact tgccatcttt atcttttgaa
    20161 cgcataaatc ctgactcata gtcaaagata ttttgatagt tcaatgattg ctgctgatat
    20221 ttcttcgtca tttcctcttc ttctagtacc ttggcaactt ggctaataca aaaatcgcta
    20281 taagcatagt ctaatgtgtg attgactgat tcgtggtagt gattaggaac atagccatat
    20341 gtcaagtaat cttctgttcc ttggcgtcca taatttggat gtttgctttg aaccgtagca
    20401 cctttttcca ttgccgttag aaattcaggc atcaagtctc gtcggatatc ttttacagca
    20461 gcatctgcaa tgaccgcatc gatcaatgtc ccaggcataa gtccacgttc atcaggagac
    20521 agccattttg gcaaatagcc actttctcta tagctgttca aaaaaccttc cagcatttct
    20581 tcgtattttt ctacagcaat caaagaataa agaggataaa ccgttttata cgtatcccaa
    20641 aacccattat ttgtatagag aacaccaggt tttatagatc gactagtcgt atcatagtgg
    20701 attttttgcc cactaggatc aatttcataa aatgtttgtg gaaataaaaa cacccgatat
    20761 aaattatgat aaaacgtccg caattgttgt tgatcatggt gtgtgagctg tatacgatca
    20821 aaataggact gccattgttc ttgactgtga gcaaggtaag tctctttgct ttggttttgt
    20881 tctagttcca ggttataagc tgcttgttcc gagctgataa aagatgtccc aaatcggata
    20941 gtttgttttt ttgtctgttc aaaatacaac gggatcgagt cgctattttt gttggaaaca
    21001 gctaactcat caattgttaa aggatattca aatctcaata taaaataaaa agaaaaatca
    21061 ggatcttctg aaccagcaaa atgtgtgatt tttccttcca ctgtgtaagg atctataaca
    21121 aagagctgat ggcgtcccgg aaaggataaa agtaaaccgc tgtcattttt gctgtaatca
    21181 atagataaga ttccgccata catgctaggt atcaatgtag aacagatgcc ataacgtaat
    21241 tgacagatcg acagatgagt cgggcaaaat atactttctt ctgggcggta agaactttga
    21301 gcatggaaaa gggtgttctc ctgtagtttt ccattgatcg gcgtaaacag catatgactg
    21361 aaatcaccca tccaaggact tggttgatgg gtaagacggt agccttgaaa aacgcggtca
    21421 tcaggatgaa accaccagct gccgttttga tccgtagttt gcggtgcaaa ataattcatc
    21481 ccaaaaggaa cgccagtata aggctggcag ttcccattag agaaatttgg ctgattcgct
    21541 gttgcatgtc tagtatctat ttgaccgata ttcattttat ttctcctttg ttgattgtct
    21601 tttgatgaat gaaactggaa atttactatc ggatggtcga tcttttgtct ctaaccaagt
    21661 gaccaaagca tctcccgcaa gcttacctaa ctgttcaaaa tcttgtgcga tggttgtcag
    21721 tggcgggtca acaagagctg ctgcttggat atcatcaaat ccgataattg aaaaatcttc
    21781 agggatatga taaccatgct gtctcaagag attcatggtc tggatagcga caacatcgtt
    21841 ttcacaaaca aaagcagtta cttcatactt agtgatataa gaaagcaatt catctaatgt
    21901 cgcgcttttg tcatccagtg aagtgtggaa agtcaaacca gctttgtcca atgcttcaag
    21961 gtaaccaagg taacgctgtc gaacggattg tggatgagtc tgcgtaccaa acaaataagc
    22021 gatttttgaa tgtccctgtt cgatcaaata agaggcagca agcgcaccgc cttggaaatt
    22081 atcggaaaga acggtaggaa aaggtaactc atagattttt ttatctaata tgacgacagg
    22141 gaattctttc aatgaaagct caaaaagtaa gtcaagatgt tgttctgtat caagagcata
    22201 ataaatcaat ccgtcaaatt cattgattag ctcttttgct gttttatttt gtagaaagtc
    22261 aagcgtcgtc atcatgacat caatctgttt atcttgcatc acagggttca atcccttgct
    22321 aaaatcacca acagacaaat cagcgacata tggaagaaga aacagaatcc gtcgtgtttt
    22381 tgtaggagaa gcaagaatct gttccggaga agcggattta acgaaactgc ctttcccgcg
    22441 aacgcgataa ataagtccta attgctctaa ttcagtcaat gcacgtttgg aagtgattct
    22501 gcttacttta taggtacgtg aaagttcttt ttcagttggt agttggctgt ctacaggtaa
    22561 ttcaccagtt aaaatagccg tttgcaaatc attaaatatt gtctggtaca atggttgagt
    22621 catataaaca cctcttaatg atatatcata ttcaaataat accataatgg atgaaaaagt
    22681 aaataaaaag atattttttg aaagcgtaga cataattggc tgtatgaagt ataatcttta
    22741 aagatatatc aaatagaaag aaggttttat tagtggttta taaagatata ccaaaatcgg
    22801 tgcagaaatt tatggaagat atcacacaaa aatgtgggga tatccatgcg gactgggcaa
    22861 agaattttac agcagcattt gccaatactc tgttgacaac agtcaaaaag caaaatgacg
    22921 gaaccacctt tttattgacg ggagacattc cagcgatgtg gttaagagac tctactgcac
    22981 aagttcgtcc ttatttagtg attgcaaaag aagatgagga attagctgac atgatcagcg
    23041 ggttagtcaa aaagcaattt ttttatatca atatcgatcc atatgcgaat gccttcaacg
    23101 aagaagctaa cggtgctggc caccaaacag atcatacaaa aatgaacgat tggatctggg
    23161 aaagaaaata tgaaattgat tctttatgct acccaataca gttggcctat cttctttaca
    23221 aaaatacagg aaaaactgat caattcaatc aatcttttat tgaaggtatc aaaaaaatct
    23281 tggacgtgtt caaaacagag caagatcatg aacactctcc ttatacattt gtacgagaca
    23341 cgacaagaaa agaagatacg ctgatcaatg acgggcgagg tgcaaaaaca gcttttacag
    23401 gaatgacatg gtctggtttc cgtcctagcg atgatgcttg ccgttatgga tatctggtac
    23461 catccaatat gtttgcggtg gtcgtgttag gttatgtgga agaaattttt caaacgatac
    23521 tcgatgataa agaaattgta cagcaaacac agaaattgaa gaaagagatc caagagggga
    23581 ttcagaatca cggacgaacg gttaatcaaa aagggcaaac gatttatgca tatgaagtag
    23641 atggaatggg aaacgccaca gtcatggatg acagtaatgt gcccaatctg atcgccgcac
    23701 cttacttggg atattgttct gaacaagagg aagattatct gcaaacaaga agaacattgt
    23761 tgagtaaaga aaatccatat ttctatgaag gaaagtacgc aaaaggaatt ggatcctccc
    23821 atacgccaga aaaatacgtt tggccgattg cattagctat ggaaggaatg acaacgtcag
    23881 acaaatctga aaaagagcgg atattgaatt tacttgtagc aactgacgca ggaacacacc
    23941 ttatgcacga aggattcgat gtgaacaatc ctgaaaatta tacgagagaa tggttttctt
    24001 gggcaaatat gatgttttgc gaattagtca tggattactt tgatattaga gtagaaaagt
    24061 aggaggtatc gtaaatgaaa aagaaagtat atatcatttc tcatagccac tgggatcgtg
    24121 aatggtacat ggcttacgaa cagcatcaca tgcgactgat tgaattgata gacgatctac
    24181 tagagctatt tgaagttgat ccgtccttca acagttttca tttggatggg caaacgatta
    24241 ttttagatga ctatcttcaa gtaaggccag aaaaaagaca ggcaatccaa caagcaatca
    24301 atgaaggaaa attgagaatt ggaccatttt atatcttgca agatgatttt cttatcagct
    24361 cggaatcgaa cgtgagaaat atgctgattg gcatggaaga aagccgtaaa tggggaaccc
    24421 ctgtcatgtt aggctatttt cccgatacat ttggaaatat gggacagacg cctcaattaa
    24481 tgaaacaagc tggtatttca gcagcagcgt ttggccgtgg tgtaaaacca attggctttg
    24541 ataatcaagt tttggaagca gaaaactatt cttcccaata ctcagagatg tggtggaaag
    24601 gccctgatca aacagcaatc tttggtctgc tatttgccaa ttggtatagc aacgggaatg
    24661 agattccagt agaaaaagaa gcagctcttg ccttttggaa gcaaaaatta gcggatgcag
    24721 aacaatatgc ctctacgaac cacttattga tgatgaatgg tgttgatcat caaccggtac
    24781 aaaaagatat atcaaaagca atccatctcg caaatgaact gtttccagat tacgagttta
    24841 ttcattctaa ttttactgac tatctggaag cagttcaaaa agatgtgcca gaagacttag
    24901 gctcagtaga aggagaattg acaagtcaag aaacggatgg ctggtatact ttagccaata
    24961 cagcatctgc tcgggtttac ttaaaacaat ggaataccaa ggtccagcga cagctagaaa
    25021 atattacaga accacttgcg acgatggctt atgaagttag tggaaactat ccccatgatc
    25081 aattagatta tgcttggaag acattaatgc aaaatcatcc tcacgacagt atttgcggtt
    25141 gttcagtcga ttctgtccat cgggaaatga tacctcgttt tgaaaaagca gatgaagttg
    25201 gaaagtatct tgcacaagat tccttagaac agctgaccgc agcaatcgat acgaccggat
    25261 tcccaaaaga cagctttcca tttgtcattg taaatactgc aggaatggat aaaactggtg
    25321 aagcagaaat aaccatcgaa ttagaaagaa aaagattcgc tgaaggaata cctgaacaac
    25381 tatatcaaga gttagaaaat ttgcctaaac gtaagtatca tgtagaaaca aaaagtgggg
    25441 ccactatacc agctatttta tctgaagaaa ctgtccaatt tggttatgat ttgccgaaag
    25501 accgtttccg tgtgccatat atggcaagaa tgatcaaagt gactttacca ttagaaaaca
    25561 tgccagcatt ttcttgggaa acattcgcgc ttgtagaagg ggaagcgaaa gcagaagaaa
    25621 aggaaacaat gattcatcag agtggacgaa tcatcgaaaa cggccctcta catttgacga
    25681 ttgaaaaaaa tggtaccatt acaatggaag atcgcaaaaa caaacgaaag ttgaataatc
    25741 tgcatatttt tgaagatatc ggcgatatag gaaatgagta tatctttaaa caacctttct
    25801 gtgatcagcc aatcctatcc agtaacaaag aaaactctga agtaaaagta ttagtagata
    25861 caccggaaat agcaaaaata agtattctac aggaaatgga aatccctgtt tctgcagacg
    25921 agcgtttaga aaaagaacag cagatggttg tggaatttcg ttatcgaaaa gcagaacgat
    25981 ccaaagaaaa acgaatcctt caaataaaaa caatcatgac aatcagaaaa gatagtaaaa
    26041 aaatcgactt tgaaacgact ctcgacaatc agatgaaaga tcatcgctta cgtgtcttgt
    26101 ttcctacaaa gttacatgtg gaacatcacg aagcagatag tatttttgaa gtggtgaagc
    26161 gcccaaacca tgtgtctaaa agttgggaaa accccacgaa tccgcaacat cagcaagcat
    26221 ttgtcaatat tcatgatgaa gagtacggtg taacagtcgg aaactttggt ttgaatgaat
    26281 atgaagtaac agaagacgga caaatcgcag tgacgctact tcgcagtgtg ggagaactag
    26341 gcgattgggg atattttcca acaccagaag cacagtgtct aggtgagcat cggttcaatt
    26401 acagcattga actacatgga ccagaagaaa aattctctac ttatttgcat gcatacgcag
    26461 cacagattcc tttttccact caacaaatca aacatcatga aggaacattg atttcaaaac
    26521 aacaatattt aacgataaaa agtgaaacgt ttgcaattac agctttgaaa cgcagcaagt
    26581 ttagtgataa agtagtagta agaggtttca atatgtctag tcatttagaa aaattggaaa
    26641 taactaaaga caatggaaaa actgtcatat tgaatctgct tgaagaacca acgaagcaag
    26701 cggttgtccc aataatccaa ccttatgaga ttcggacaat cggattcgag gaggaaaacg
    26761 aatgtatggc ggaatagaag caggcggaac aaaatttgtg tgtgcggttt cagatggtgg
    26821 agaaatttta gaaaaattaa gtatccctac cacaacacca gaagaaacat tggatcaggt
    26881 atttgaattt tttgatcgtt atgaattgaa gggaatcggg attggctcat tcggcccgat
    26941 tggtatcgac aaaacaaaag ataattacgg atacgttttg gcaactccca aaaaagggtg
    27001 ggcacaattc gattttcttg gcacaatcaa ggaacgctac aatattcctg ctgcttggac
    27061 aacggatgtc aatgctgctg catatgggga attgaagcaa ggagcagcac aaggaaaaaa
    27121 tagttgtatt taccttaccg tgggaacagg aatcggtgca ggtgtcgtga tcaatgaaga
    27181 aattttttca gggatcgcac atcctgaaat gggacatatt tgggtgaaac gccatccaga
    27241 tgaccattat gaaggtactt gtccttatca taaagattgt ttagaaggat tagcagcagg
    27301 accgtctatt gaggcacgca cagggatcaa agggcaagat ctgccgcaag atcatcctgt
    27361 ttgggctatt caggcttatt atattgctca agcactgatc aactatacgt tgacgttagc
    27421 acctgaaaag attattttag gcggtggggt aatgaatcag gatcatctcc ttcaaaaaat
    27481 ccgtcagcaa tttgttgaat tgatgggtgg ttatatggaa acacctcaag taagtgaata
    27541 tatcgttcgt tggggactgc cgaatgaaag tgggattatc ggtagtttgc tgttagcaga
    27601 acacgaacat caaaagtaag cagacaaatt acacaaaaag aacagagtct tatcattatc
    27661 tgctgataag actctgttct tttttatttc tattcccata atccaggtaa agctttaccg
    27721 actatttttt cttgagtaaa tggatggatc atgtgcagtt ctaatgcatg gagcatcagt
    27781 cgttcagctg ttctattttg gtagagaggg tctccaacga tcggatgtcc cttatgagct
    27841 aaatgaactc tgatctggtg tgtacgtccg gtttccaaaa cacaatagac ttgtgtttgt
    27901 tcagaaagta ctttgttgac agtgacatgt gtcaaggcgc tctgaccatt tttatcatct
    27961 acgacccttt ttctccgatc atggcgatct cgtccaattt tattggtgat ggtcatatct
    28021 ttggcaattt ctccccatac gatggcttga tatctccgat agatcatttt ttgttccaac
    28081 attcttccaa gtatcggcaa gacaaatgga ttttttgcaa ataaaacggc accgcttgtt
    28141 tctttgtcca agcggtggac aacgtaaggt cgttgctgtt tagtgtcgag ataagcagct
    28201 aaatgattga gtaaggtact gttttctgtc ggttcatttg gatgagtctt cattcctgca
    28261 ggcttatcca ctataatcaa atgctcatct tcatataaaa cacggatgtg cttcgcatct
    28321 cctaattgaa cttcttgata attataatct gtttcttcga ataacaatgt gatctggtca
    28381 ttgcccttta cttcatgatg gaacaaagca ggttgttgat tgatccaaac gtttttacgt
    28441 atacgcaaaa agtgtcgaac ctttctagga actaaccatt ccttttcaag caagtcgcga
    28501 attgttgttt caggatggtt cataggtaaa gtgatcgtga ttttcacaag tgtactcctt
    28561 tcagtgcaat tgcagactaa ttgtaccatt tttaaaacat atttaagaaa aaacttacat
    28621 ttttctgttc attcttatgt tactctactt gcactaacgt aaaaaaacat attgaactac
    28681 aacttaagca ggaagaaaac actctttcac tatggtaaaa taagacgatt gaatcaaata
    28741 gacaggagaa gaagcaaatg gattttcaaa gcattttaga aaagataaaa gctgctttga
    28801 tcagtttttg gcgttggatc agaccatatc tcggacaatt ccatcgatgg cgaaagcgca
    28861 tctggaaaaa atatcatgtg aacaaattga ttttgctgat tggtttgatc tgtgtcttag
    28921 tgacaagtat ctacctcttt attttagcaa aacaagcaaa tgtcgaaacg ttaaaatcag
    28981 gattaagcca atcgacagtc atttatgata agaaaaacga agaagctggc acactgtacg
    29041 cccaaaaagg aacatatgta gaattaaacg cgatttctcc ctatatccaa gatgcagtaa
    29101 tctcgacaga agataggaat ttttacgagc atcacgggtt tgatatcaaa gggattgccc
    29161 gtgcagcagt ccgaatggtc ttgtctggcg gaacatcagg gggcggagga agtacgatca
    29221 ctcagcagct tgccaaaaat gcgtatctga cattagacca aacgtttgat cgaaaagcga
    29281 aggaattatt tttggcaatc gagatcgaaa agaagtacag caaagaagaa atcttgacca
    29341 tgtatcttaa caatgcctat tttggcaacg gggtatgggg tgtccaagac gcttccagaa
    29401 agtattttgg agtagatgca acgaatgtta cgctgtctga ggctgctact ttggcaggaa
    29461 tgctgaaagg tcctggtatt tataatccga tcgatcaccc aaaaaatgcg aatgatcgga
    29521 aaaacacagt actaagtgta atggaagaaa acggaaaaat cacaaaagaa caagaacaag
    29581 cagaaagcca gacagatatc agcgcgtatc ttaatgacac atacgataat tcagattctg
    29641 gttatcgtta tccttattat tttgatgcag tgatcgatga agcagttaac gagtatggtc
    29701 ttgatgaaga agatgtcatg aataaaggct ataaaatcta tacagcttta gatcaggatt
    29761 atcaaaagca attagaagct acttatcaaa acagtgcatt attcccagca aatgcttcag
    29821 atggtgccat ggtccaatct gcttcagtag ctttagatcc gaatacaggt ggtgtacaag
    29881 cactagtagg acgaagagga gatcatgtct ttagaggatt cagctttgct acacagatgc
    29941 gtcgttcacc aggatcaacg atcaaaccat taagcgtata tacaccagca ctggaagctg
    30001 gatacaagcc ttccagtatc ttgaaagacg aaccgcaaag ttattacgat gcgcataatt
    30061 ttgacgggac ataccaagga gaagtaccga tgtatcaagc tgttgcacaa agtttgaatt
    30121 tgcctgctgt atggcttttg catgagatcg gtttacaaaa aggatatgat aaagcagaag
    30181 aattcggcct gcctttagca aaatctgata agtattatgg cttagccctt ggtggactgg
    30241 aaaaaggagt atctccattg atcatggcgg gtgcttacag tgcatttgcc aatgatggtc
    30301 agatgtatac gccgcatctt atcacgaaaa tcgttgattc gactggagcg gtgatcgtcg
    30361 ataacacaaa caaaaaacca aaacaggtca tatcaaagga aacagccgat gaaatgacca
    30421 gcatgcttct tggtacattt tcaaatggaa cagcggctgc tgcgaatcct gcaggttata
    30481 cgatagcagg gaaaacagga accacagaaa ctaatttcga tgccacaaaa gcaaatgacc
    30541 aatggatgat cggttacacg ccagacgtag tgatttcgac atggatgggt tacgaagaat
    30601 ccagcaagct gcactatttg gaagggacaa gtggaaatgt tgtcgggaaa gtcttcaaat
    30661 cagcggcaga aggcatcctt ccgtatactt caaaaacagg atttagtgta gcagatgcct
    30721 atgccacagg aggacaagtg gtagctgcag atcaagttgg aaacacagga aattctaatg
    30781 gagagtctgg aaattggcaa gataacttga atcaatatgg tgaacaagca aaagaagggc
    30841 tgaaaaactt cggcgatatg gtgaaagaag gcgttcaggg aattggtgaa gcggctaaag
    30901 acctctggcg gaaatatcaa ggagagtagc ccctttgaaa acgaataacc ccatgttaca
    30961 atagagagta actactaaaa gaaaagaggg cataacatgt caaacatcta cgatagcgcg
    31021 aatcaaatcg aacgtgagat ccgtgaatta ccagaattca aagcgttgaa agaagcgtac
    31081 gagaaagtac aagcaaacga agaagcacac aaactgttca aagacttcca agcgatgcaa
    31141 atcgaattac aagaaaaaca aatgagtgga caagagttca gcgacgaaga tgcaatgaaa
    31201 gcacaagaaa tggctgtgaa aatccaatca gaagaagtaa tcaatgactt gatgcaaaaa
    31261 gagcaaggct tcagtacaat catcaatgac ttgaaccgta tcatcatgac accagttcgc
    31321 gacctttaca gcgaataaaa ctattttatg aaacaacaga gggtgtgaaa gagacgttcg
    31381 gccttgagcg atgacaaaat tgcttcttat tgccgatagg ctgtctcttg aacaccattt
    31441 accaagaggt cgtgagccta ccgtttaact ctgagttaca aggaacaatt tcaaaaaaca
    31501 gcttctcatg tttgatgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
    31561 ttattcagaa ataggagcta cgacaaaagt cttgtcatag ctcctatttt ttgtcattca
    31621 tttttcaagc ggtagaaata gcctttttga gctaacagtt tttcgtaagt acctatttca
    31681 acgatttttc cttcatcgat cacaacgatt ttatctgcct ctttgatcgt tgaaagccga
    31741 tgagccacaa taaaagtagt gggtgtttct gtcaggtaat tcagggcttg ctggattttt
    31801 ttctctgact ggttatctaa agctgaggtt gcttcatcta gcaaaatgat ttttggctga
    31861 cgtatcaacg ctcgtgcaat ggagatacat tgcttttggc caccagacag cttgttgcca
    31921 tgttcgccta ctaaggtatc cagaccatca ggaagctggt caatcagtga agaaagttgc
    31981 gcagcttcga tgacttcatc taaacgttct tttgatacgt ttttcaagcc ataagtgatg
    32041 ttctctttga tcgaagcgga gaacaacaaa gtggtttgag gaacaacggc taaataattt
    32101 cgcacacttc gcatatccag ttcatccaaa ggctgatcat ctagaaaaat ttttcctgaa
    32161 gtcggctgga taaatccaat caataagtta aggagtgtag attttccaga gccagatggc
    32221 ccaacaaaag caattgtttc tccagctttc acctctagag aaaaatgatc gataatcggt
    32281 ttgagtgagt ccggataaag aaaagaaaca tcctcaaaac gaaaatttcc atccaaatgt
    32341 tggatttttt tcttaccgtg ataagtttct acatcgccag caatcaacag ttcgccaata
    32401 gaagtgatag attccatgcc ttttgaaatc gtaggaatca gcgtgatcat tccagaaacg
    32461 gaattgacga tcgtcgtgaa atacgtctga tacatcacga catcgccggg ttggatgcgc
    32521 ccttgtaaag ctaatatccc agtgaaactc aaacaaatca gctgaaatat ctgaaaacta
    32581 gcccagctga ctgatccgaa aacagattgc aggatatcta agtggaatcc tttttcatag
    32641 atttgagtaa aatgcttatt taagcgagtt gtttcgtgtt tttctaaccc atgagctcga
    32701 gcaatcggtg ctaattcgat cacttcgatc acttttgcag aagtctcttc catttcttgc
    32761 ctgaagtctg agttggactg tctgatcctt ttacggaaaa agagagtaac gaatgcggcg
    32821 agaggaacag tcaataagaa aaacatgaaa acaacaggac ttttataaag cgtgatacct
    32881 aaagctacga ataaattgac agcgatattt aatccgctga caaatacttg agaggacaac
    32941 gtttggatag cttctacatc acggatgatc tttgactgga ttcgtccaga ttgcaattct
    33001 ttttgataag gaatagatag ttcttggatt ttcttgataa gggtcgctct tagtccagct
    33061 tctacttgac ggatcgaagt gctatggtat tttacatgaa aataattcgt caatatattt
    33121 tgaccaatca gacaagccat caaaaaagcg ttgaaataaa tggcctgcaa ctgagaagaa
    33181 tctttcgatg aagctgcatt gattacattg gcaatagcga tcggcattaa ccaagatgga
    33241 agatgtttga taataaaaaa gagtcctgac atggcaaaac gccaataatt tccctgataa
    33301 agatgcagca atgtctgaaa agcatttgca tgatattttt gataactttt ctgtattcgt
    33361 tcctccataa tcttctcctt aacaatcttg gtaaataaac tgcaagtgtt ctattgcttc
    33421 aggaacataa atctcaggag tagcttcaag agtggcgtac attagaggac gctcatattt
    33481 gatataatgc agtaccgggc ggaaatctaa acagcccttg ccaacaggta ccatgcggat
    33541 ctttccattt tccatgatat agtctttgag atgaagcgct gtaatataac catgtaaatt
    33601 gtccaaggca cctcggatca ctttttcctg atcagcatga ttttctttat gcatcaaatt
    33661 cgcacaatct aaaatgattt ttaaatttgg tgaagctact tcatcgatta aacgtttagc
    33721 taactgatag ttatagattg gatgattgat ccctgcttca acagcaacag ttacgccaaa
    33781 attttctgca tgagcgacta attcaatgat agaatttctg gcgatctgat aagcttcttc
    33841 agtaaaattt tcttttgtgt aaccgacaga gacactaccg gtttccgtag caatcatctt
    33901 ggcttgatag gcagagcaca gagcaatttg ctgtttgaaa gttgccaatg cttgtgcacg
    33961 aacttcttga tttttgctgg ataggttgat atagcatcct aaaatggaaa gttcgatatt
    34021 gtttttttgg aagtattcac caaaataggc agcactccca agtgtcatgt cagttaattt
    34081 aagttgttca ggaaatgctt tttgtggtgc aaattggata tgggacaagt gaagctgtga
    34141 tactttttga acgatttctt cacgatttcg aacatctaaa tcgtgggcac ggatgcctaa
    34201 atttaatgga aacatctcaa actccttttt gtaaataatt agcaagaggc agacgggatt
    34261 cttttatcaa ttcaacaatt attcgggcaa ctttatcagc gccttctgga ctaaagtggg
    34321 tattgtcttt tagtccttct gggtaatttt tacaagtatc aggcataaga tgcaggtaga
    34381 atttttttgt ctcttctttt gagaaggtct ggaacaattc ttgtgatctt gagaacacat
    34441 ctaaaagagg aatatggtgt ttctcagcaa atgcacgcat cgcttttgga tagtctccaa
    34501 gtatatctgg attcaatgtt ccgttttcta agtaatctcg tcgcgtcaca gatgtcagta
    34561 agaccatttg gacgttcgct ttttttgcgc attcaaaaaa tatctgcaga ttttttaaat
    34621 agctaccgaa gggaagcgta cctctttctt cttggatttt ctggtcgtta tgtccaaatt
    34681 gtacaaataa gaaatcattc ggctgaaact gtgaagctag acgggctaac cttccttcct
    34741 ggataaatga tttggtgctg cgtccattct ttgcttggtt attgatctgg atctcgggtg
    34801 aaaaataagc agagattttt tctccccaac ctgtctcggg acgcttgttt tcatcttttt
    34861 ctgccgcagt agaatcaccg gcaatatgga tagtaggcat gttatctctt ctttcataaa
    34921 ggtttatagg caatgaagca gaacagcaag agaagaagac ggagcaa
//
LOCUS       DAFKHN010000024        34607 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFKHN010000024 DAFKHN010000000
VERSION     DAFKHN010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.024"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="LY912_001158"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="LY912_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBM6954868.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="LY912_001159"
     CDS             complement(2020..2922)
                     /locus_tag="LY912_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBM6954869.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="LY912_001160"
     CDS             complement(2919..3611)
                     /locus_tag="LY912_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBM6954870.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="LY912_001161"
     CDS             complement(3654..4295)
                     /locus_tag="LY912_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBM6954871.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="LY912_001162"
     CDS             complement(4333..4647)
                     /locus_tag="LY912_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954872.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="LY912_001163"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="LY912_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="LY912_001164"
     CDS             complement(5984..6916)
                     /locus_tag="LY912_001164"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBM6954873.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="LY912_001165"
     CDS             complement(6913..7689)
                     /locus_tag="LY912_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBM6954874.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="LY912_001166"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="LY912_001166"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBM6954875.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="LY912_001167"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="LY912_001167"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBM6954876.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="LY912_001168"
     CDS             complement(12014..13294)
                     /locus_tag="LY912_001168"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBM6954877.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="LY912_001169"
     CDS             complement(13313..14239)
                     /locus_tag="LY912_001169"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBM6954878.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="LY912_001170"
     CDS             complement(14252..15535)
                     /locus_tag="LY912_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBM6954879.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="LY912_001171"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="LY912_001171"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBM6954880.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="LY912_001172"
     CDS             complement(16323..17234)
                     /locus_tag="LY912_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBM6954881.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="LY912_001173"
     CDS             complement(17231..17695)
                     /locus_tag="LY912_001173"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBM6954882.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="LY912_001174"
     CDS             complement(17700..18398)
                     /locus_tag="LY912_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBM6954883.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="LY912_001175"
     CDS             complement(18385..18771)
                     /locus_tag="LY912_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954884.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="LY912_001176"
     CDS             complement(18918..20588)
                     /locus_tag="LY912_001176"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBM6954885.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="LY912_001177"
     CDS             20771..21004
                     /locus_tag="LY912_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBM6954886.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="LY912_001178"
     CDS             complement(21103..21534)
                     /locus_tag="LY912_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBM6954887.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="LY912_001179"
     CDS             21613..22026
                     /locus_tag="LY912_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBM6954888.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="LY912_001180"
     CDS             complement(22064..23212)
                     /locus_tag="LY912_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBM6954889.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="LY912_001181"
     CDS             complement(23334..23930)
                     /locus_tag="LY912_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBM6954890.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="LY912_001182"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="LY912_001182"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBM6954891.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="LY912_001183"
     CDS             27160..27591
                     /locus_tag="LY912_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6954892.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="LY912_001184"
     CDS             complement(27636..28985)
                     /locus_tag="LY912_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBM6954893.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="LY912_001185"
     CDS             complement(29055..30218)
                     /locus_tag="LY912_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBM6954894.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="LY912_001186"
     CDS             30347..30670
                     /locus_tag="LY912_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954895.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="LY912_001187"
     CDS             complement(30853..32202)
                     /locus_tag="LY912_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6954896.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="LY912_001188"
     CDS             complement(32271..33224)
                     /locus_tag="LY912_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBM6954897.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="LY912_001189"
     CDS             complement(33326..34516)
                     /locus_tag="LY912_001189"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBM6954898.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9831 a         7582 c         6083 g        11111 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaat ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gcaataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgat
//
LOCUS       DAFKHN010000025        34475 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFKHN010000025 DAFKHN010000000
VERSION     DAFKHN010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.025"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(168..2060)
                     /locus_tag="LY912_001190"
     CDS             complement(168..2060)
                     /locus_tag="LY912_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954899.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2057..3784)
                     /locus_tag="LY912_001191"
     CDS             complement(2057..3784)
                     /locus_tag="LY912_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954900.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3800..4450)
                     /locus_tag="LY912_001192"
     CDS             complement(3800..4450)
                     /locus_tag="LY912_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBM6954901.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4654..4950
                     /locus_tag="LY912_001193"
     CDS             4654..4950
                     /locus_tag="LY912_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBM6954902.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5122..5742
                     /locus_tag="LY912_001194"
     CDS             5122..5742
                     /locus_tag="LY912_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBM6954903.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5834..7000)
                     /locus_tag="LY912_001195"
     CDS             complement(5834..7000)
                     /locus_tag="LY912_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBM6954904.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7012..7365)
                     /locus_tag="LY912_001196"
     CDS             complement(7012..7365)
                     /locus_tag="LY912_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBM6954905.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7493..8515
                     /locus_tag="LY912_001197"
     CDS             7493..8515
                     /locus_tag="LY912_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBM6954906.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8534..8695
                     /locus_tag="LY912_001198"
     CDS             8534..8695
                     /locus_tag="LY912_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954907.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(8954..9388)
                     /locus_tag="LY912_001199"
     CDS             complement(8954..9388)
                     /locus_tag="LY912_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954908.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9498..11357)
                     /locus_tag="LY912_001200"
     CDS             complement(9498..11357)
                     /locus_tag="LY912_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBM6954909.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11475..12635)
                     /locus_tag="LY912_001201"
     CDS             complement(11475..12635)
                     /locus_tag="LY912_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBM6954910.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(12942..14366)
                     /gene="araA"
                     /locus_tag="LY912_001202"
     CDS             complement(12942..14366)
                     /gene="araA"
                     /locus_tag="LY912_001202"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBM6954911.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14382..15080)
                     /locus_tag="LY912_001203"
     CDS             complement(14382..15080)
                     /locus_tag="LY912_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBM6954912.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15037..16698)
                     /locus_tag="LY912_001204"
     CDS             complement(15037..16698)
                     /locus_tag="LY912_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBM6954913.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            16916..18316
                     /locus_tag="LY912_001205"
     CDS             16916..18316
                     /locus_tag="LY912_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBM6954914.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18568..19647)
                     /locus_tag="LY912_001206"
     CDS             complement(18568..19647)
                     /locus_tag="LY912_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6954915.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19733..20692)
                     /locus_tag="LY912_001207"
     CDS             complement(19733..20692)
                     /locus_tag="LY912_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBM6954916.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20704..22215)
                     /locus_tag="LY912_001208"
     CDS             complement(20704..22215)
                     /locus_tag="LY912_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBM6954917.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22237..22800)
                     /locus_tag="LY912_001209"
     CDS             complement(22237..22800)
                     /locus_tag="LY912_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBM6954918.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22806..23669)
                     /locus_tag="LY912_001210"
     CDS             complement(22806..23669)
                     /locus_tag="LY912_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6954919.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23683..24579)
                     /locus_tag="LY912_001211"
     CDS             complement(23683..24579)
                     /locus_tag="LY912_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6954920.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24754..26043)
                     /locus_tag="LY912_001212"
     CDS             complement(24754..26043)
                     /locus_tag="LY912_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6954921.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26015..27532)
                     /locus_tag="LY912_001213"
     CDS             complement(26015..27532)
                     /locus_tag="LY912_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBM6954922.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27730..28620
                     /locus_tag="LY912_001214"
     CDS             27730..28620
                     /locus_tag="LY912_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBM6954923.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28693..29517)
                     /gene="nadE"
                     /locus_tag="LY912_001215"
     CDS             complement(28693..29517)
                     /gene="nadE"
                     /locus_tag="LY912_001215"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBM6954924.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29529..31001)
                     /locus_tag="LY912_001216"
     CDS             complement(29529..31001)
                     /locus_tag="LY912_001216"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBM6954925.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31638..32000)
                     /locus_tag="LY912_001217"
     CDS             complement(31638..32000)
                     /locus_tag="LY912_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBM6954926.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32223..32975
                     /locus_tag="LY912_001218"
     CDS             32223..32975
                     /locus_tag="LY912_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBM6954927.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33115..34038)
                     /locus_tag="LY912_001219"
     CDS             complement(33115..34038)
                     /locus_tag="LY912_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6954928.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34053..34325)
                     /locus_tag="LY912_001220"
     CDS             complement(34053..34325)
                     /locus_tag="LY912_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954929.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10176 a         7187 c         5930 g        11182 t
ORIGIN      
        1 tttgacctga gtattagaga tacaaaacgg aaaaatagct tctcatattt tgccgttttt
       61 tgagctaata ccgaaggaca gctgattgaa caccgtttat tcggaaaaag ggactgtgac
      121 acgacttttg tcacagcccc taaaaaaaat aataaatttg tactattcta tgaagcttct
      181 tcttcagaaa actgactgtt ataaagatct gcatagaatc cgtctttttc catcaatgta
      241 tcgtggtttc ctgtttctac gatcgaacca tgattcatca caataatgtt gtctgcatcg
      301 cgtattgtag acaagcggtg agcaacaacg aaacttgtcc ggttttccaa taggcggttc
      361 atcgcttttt gaatcagtat ttctgttcgt gtatctacac tagatgttgc ttcatcaagg
      421 atcaggacat ctggatttgc taagaatgcc cgcgcaattg tgattagctg acgctgccct
      481 tgcgaaatat tgcttgcatc ctcgtttaat acagtgttat atccttctgg caatttacga
      541 acaaaatcgt ctacgtgagc agctttagca gcctcaatga tttgttcgtc tgttgcatcg
      601 tcgttcccat atttgatatt gtcatagata cttcctgtaa acagccaagt atcttgcagt
      661 accattgaaa actgtgcgcg caattcatca cgtgaaagat cacgggtatc tacaccatcg
      721 taacgaatac tacctccaga aacatcgtag aaccgttcaa gaaggttgat cagtgtcgtc
      781 ttccctgcac cagtcggacc tacaatagcg accatctcac caggtttgac atccaagtta
      841 aaatcagtca ttagcaagtt atctggtgtg tagccgaatt gaacattttc aaaacgaact
      901 ttgtatggtg tatctttttc ttctggaagg ccagattttt cattggacat ctcttcttca
      961 tccaacactt caaatacccg ttcggctgaa gcaactgttg attggatagt gttcatcaaa
     1021 cttgcaagtt gagtgattgg ttgagagaac tgtgttgtat attgcaagaa cgcttgaaca
     1081 tcccctaatg tcatgttccc atttgcaact tttactccgc ctagtacagc gacgaacaca
     1141 tagcctagat ttttaacgaa attcatcaac ggcatgatga ttgccgaaat aaattgagct
     1201 ttccaaccag cggcatacag attctgattt tctttttcaa atacttcctg gtctttttca
     1261 gtatgattga atgttttaac aatggtatga ccaccatatg tttcttctac ttggttattc
     1321 aataaaccta aacttttttg ctgatctgcg aaaaacactt gtgatttcgg cgctacgatc
     1381 atcacgatga tcaagcttaa agggatcatc aataacgcga ctaacgtcaa ttgccagctg
     1441 attgaaagca tcatcacgat gaccccaatc aatgtgactg cactagttac aaattgagtc
     1501 aaattttgct gcagcgtgct tgcgatgtta tccatatcat tgattgctcg agacatgata
     1561 tccccatttg tatgtgtatc ataataggaa atcggtacac gattcatttt ggcttccaaa
     1621 tcatgacgta attcataaac tgttcgttgg gaaacacgtg tcataataaa ttgctgtaaa
     1681 aagttgaata cagcagaaat caaatacatc acgattactg tcgcaatgat ctgcgcgatt
     1741 ttatcaaagt ctatcggaaa ttttgttact tgttggcctt gttgcatctg ttgagcgcca
     1801 gccattacac ctttgaatat ttctgtggtt gctttcccca agacctttgg tgtttggatt
     1861 tggaagatca cggctgctat tgctagtaca aatacagcga tgatcgcaac catacgttta
     1921 gacatatagc caaacaatcg gcgtaccgtt ccccagaaat ttttaggctt ttcacctttt
     1981 acaccgagat ttctgccagg tccaccatgt cctggaccgc ctgctggtcc atgagaggga
     2041 cgtgtgtttg ttttactcat gctaagtcct cctctcttag ttgtgaatga acgatttctt
     2101 gataagtttc gtttgttgct aatagttctt catgtgttcc tttgccaacc agttttcctt
     2161 catctagcac aaggatcata tctgcatcca ttactgtact tactcgttga gcaactaaaa
     2221 cggtgatact ttctttcata ttcgttttca atgcttggcg aagattggca tccgttttga
     2281 aatccaacgc tgagaaggaa tcatcaaaca catagatatc tgctgttttg actaatgccc
     2341 gtgcaattgc cagacgctgt ctttgtccac cagagaagtt tcctcctcct tgttccacat
     2401 ggctatctaa gccatcttcc atctctgaaa caaaatcttt agcttgtgcg atttctaatg
     2461 ctttccaaat catttcatct gttgcatccg gcttaccata ctgcatattg tctcggatcg
     2521 ttccagagaa cagaactgct ttttgaggaa caaagcccat taattctcgc aaattatatt
     2581 gagtcatgtc actaatgtcc gttccattta tttggatcga accagattcg atgtcatata
     2641 atcgagggat caaattgact aaggtcgttt tacctgaacc agtcccccct atgattgcga
     2701 cgatctcgcc cgacttggct tggaaatcaa tatcttccaa tgcaagtttt tctgctccat
     2761 gatatcgata attgacatga ttgaaggcca atgttgcgtt ttttccagca aaagaaactg
     2821 ttttaggatt ttcagggtca tggataccga ttttttcatc caacacttca ttaatacggt
     2881 cagctgaagc ttgtgcacga ggcaccatga taaaaatagc ggaaagcatc ataaagctga
     2941 tcaagatctg catcgcataa gtcataaatg caatcagatt accgacttcc aaagtcatat
     3001 ctgctatgta gtgtccacca aaccaagtga ttgctacgtt tgtaccgctc atgatcaatg
     3061 tcatcattgg catcatcaat gcgacgatcg tattaacttt gattgccgta tttgtataat
     3121 ctttattcgc taaatcaaaa cgattttctt caaagcgtgt cttatcgaat gctcgaatca
     3181 ctctgacccc tgtcaatcct tctcgaaata ccaggtttaa acggtcagtt ttcttttgca
     3241 tacttttgaa taatggaaca gcaaagtaca tgattccgcc gatcaaaata atcattactg
     3301 ggatgacaac taagaagatt tttgtcaact gatgatcttt ttgataagca agtatgctcg
     3361 cgccaatcaa cgtgattggt gcattgatca tcatacgtaa aaacatttgt gtaaccattt
     3421 ggatttgagt cacatcattg gtcgttcttg tgatcaaaga ggccgttcca tatttatcaa
     3481 acgcatcttt tgtcagactc tctgattttt tatagacatc cgtacgcaat tgcttaccca
     3541 gtttctgtga ttcacgagta gcaaaaaatg tatttgcgat agcagctaag atactgatca
     3601 aagaaaagcc gatcatcaca aaacctgtat gccaaatata atcgacatct ccttgcgcta
     3661 cccctttatc aataatattg gaggtaagtg tcggcaaata taaatctgcc agtacttgga
     3721 tcaccatgaa aactgcagct gcaattgctg aagtcaagga gatccgtttt acgattttta
     3781 gcatctagtt cccttctttc tatttatata ctccgttttt cagccaagaa agtttcaaat
     3841 tgaattcact gattgcttgc tctactgagt aatcttcaga tgttgaaaat aagcgatacg
     3901 aatgcgcaat tgttgtaaat acagtattca tcactaattg gatcagtaat tccaattcat
     3961 gatcattttt tactttcagc ttcgtccgat cgatcaattc aagcaactct tttgcatctt
     4021 gtttgtgttc tttatgtgga tcgtgaggcg ttttttggcg actcgtatga ggagcgactt
     4081 ttcttgaggc acggtaatcc atgttcataa acaagttacg ataaaaagaa gcattctcgc
     4141 cttccaaaat ctcataaatc attttagaaa aataggattc gaatcctttg aatagatcac
     4201 catcggattc tttcattagt tgtaacatat ctttagagct gtcacgtctc attgtctcaa
     4261 agtaataaaa ataaagatcc tctttatctt caaaatactg atagaaactg cctctaggga
     4321 tatccgctaa tttgacgata ttagcaatcg aagcttcttt taagggtact ctagaaaact
     4381 cgattctcgc agcctcgatt agtctttttt gtttttcttt aggcaaatgg aaaaatgtct
     4441 gtgtcggcat atggatcctc ctttctttca agatgacaca ttgtcatatg acgctgtgtc
     4501 attataacac ctcctacctg ttttgcaaga catttgcata gtttttttca ttatcatccg
     4561 atacattaaa aaagtgataa gaggaatcct tccatttgaa ttaatgagag ttgcccatta
     4621 aaatagccac atactaaaca aaggatgaga taaatggccc aatcaattag tgtccaagac
     4681 ttcaataaat tgcctctcga tgctgacagc atcgttttag atacaagaaa taccttagat
     4741 tacacaaaaa accacttaag ccactcgctt tctatccccg ctgctatctt gccaagacaa
     4801 ttaaaaaatc tagatccaaa gaaactttat tatattctaa gctatacagg caggcgatca
     4861 gaagcattag ccgatcaact tactgctaat ggttttcgtg ctgtttatat cattggtggg
     4921 atggaagctc ttcagtcgag tgttgcttga atattgcttg ttagattcaa aagaggctgt
     4981 gacaaaaaat cgtgtcacag cctcttttat accctgtctt tttttagtta tttattcttc
     5041 aaccttatca atatgacttg atagcctttt ctttttctca tagttataac aatcatagca
     5101 ataaaaggag aaggtaagca tatggcatct gttttagtag tcaaaggtca tcccctaact
     5161 gcagaagaat cgcgcacagt taaggcattg acgtcttttt taacaagtta taaagaaaat
     5221 catccagatg atgaagtgac tgttttggaa ctttatcgcg atgatattcc ggaaatcgat
     5281 gaagaattat tatcaggttg ggaagcatta cgtgctggtg cagaattcac ttccttatca
     5341 gaaagtcaac aacaaaaaat tgctcgtttc aatgaattga ctgatcagtt ccttgctgct
     5401 gataaaatcg ttatcgcaaa cgccttatgg aatctaaata tcccaacaaa attaaaagct
     5461 tggttcgata ccgtcaatgt agctggaaaa acgttccgct atacagaaaa cgggccagaa
     5521 ggattagtga caggtaaaaa agcactgcac atccaatcta atggcggtgt atacaacgga
     5581 caagactttg cctctcaata tgtaaaaggt attttaaact ttgtaggcat cgatcaagta
     5641 gatcagctat tcatcgaagg aatcgattat gaccctgacc gtgcagatga gttgatgcaa
     5701 aatgcattag ataaagctgc tgctttaggt aaatcatttt aaaaattgag ataaatgcat
     5761 acaaaagaga cagaggaaaa aatcttcaaa gcagcatttg taccttggat attttcccat
     5821 ctgtctcttt ttgttattct ttctgctttt tcaacggatt ttcttcataa agagaagaga
     5881 ttgttgtgta ccattcaaaa acatgagtaa tcactacttt agctgctgca taaacaggaa
     5941 tccccaagat cacaccgatg attccgaaca atttcccaga agtcagcaga actaataaaa
     6001 tcgttactgg atggattgct aactgattcc ctagtactaa tggagagatc aagcgtcctt
     6061 ctattgtctg ctctactgca aaaacgatca gtactttgat gatcatgaat ggacctgcta
     6121 caatggctaa aaagatagcc ggaatcatcg ctaaaaatga tcctaagtaa gggatcaggt
     6181 tcaaaaaacc cgcaataatc cccaacgtga cagcatactc taaaccaatg accgcaaaac
     6241 caatcataaa catgattgcc acagcaaaag ccacagttag ttgtcctctt atataagaag
     6301 aaacttgact attcatttca ctcagcacat tcaacgtcgg tttttgcatg cgtgtcggta
     6361 aaaatttgac aaaataaggt gctaattgtt taccgtcttt caatagataa aataagataa
     6421 acggcatcgt cagcagagcc actaaaatag tcgctaccgc gccgacaaaa cttccaagac
     6481 tctgaactgt actcttagat atatcttgga tcatatcgcc tgccgaattc atgaacttat
     6541 cacctgctgt ttccaactgt tcgcgaaatt ggttgaacag cgggtcccgc aaaatctcgg
     6601 ttaatttatt atcaatcgta tctacatatt gagggaagtt actgatgaag ctcactgttt
     6661 gttcctgaat cttagggatg atcactacgc tcccccatgc gattagtgca acaaccaaaa
     6721 caaacagccc aatgatactg taaagccttg gtacttttcg cttttcaaag taatcaacta
     6781 ccggattcat caagtaatac aagattcctg ctaaaatgat aggcagacct acgattgcta
     6841 aaaattgcca gattggtgca aacaaatatg aaacttttgt aaataaaaag acgatcagca
     6901 atattaacaa tacaacaagt aaggctgtga ctacttgatt atttaaaaac cagcgccaaa
     6961 accacgatac cggtctgttc ttcttatttt ttccttccat aattcctcct gttagttata
     7021 aaaaatttgg cttcccaaac caatagcagg cagtctatgc ggatgaagat agattccatt
     7081 tgcaatttgt ccttcttctg gacaagcatc aaaaatcaat gatacgtgag ctactgtctc
     7141 taaattccca ttggccatcg gaccgacata atcgatcgta tatacctgat catcaaaagc
     7201 aattgttccg cctgctttca aagaaaaagg ttcgtctttt gatacttctt gaatcaccga
     7261 atattttcgt aaggcagctg ttgctgtttt atcgaacaaa atcagcatgg gttcttcctt
     7321 gtttattgct tctgtcccaa tttctgtaat ctttgcctga atcattgcac tctctccttt
     7381 aattgctttc aaaaacagta taacacattc tcattcttta gccgtgtgga ataattatgt
     7441 gatagaataa aaacgaaaac tatttcatta caattaggag gaatcagctc atatgatcga
     7501 aaagataatt ttaggaacct atacgcgtcg cgaaagtaaa ggaatctata cgatcgacct
     7561 tgatacagaa aaagaagaat tagccaacct ttcattagct gttgaagaaa atagccctac
     7621 ctatgtagca aaaagtaaag ctggcaatct ttacacagtt actagtgtgg atggattagg
     7681 tggtgccggt gcgtacgata aggattttca ttttttgaat gcggtaacag agtctggcgc
     7741 tcctttgtgt tatgtagcgg ttgatgaagc acgtcaatta ctatacgggg cgaactatca
     7801 taaaggtgaa gtaaatgtct accatatatt aggagatggc gaactgaaag cagcagattc
     7861 aatattccat caagaagcga caggtcctca taaaaaccaa gatcatgcgc atgtccacta
     7921 tacggatctg actcctgacc aacgattagt cgtatgtgat cttggtacag atcgtgtgta
     7981 tacttatgat gtgtccgaaa acggcaaatt gaatcttgta actaccttca ctgcagagcc
     8041 aggaacaggc cctcgccatc ttgtctttca tccaaatgga caattcgctt atttatttgg
     8101 tgaattagac agcacagtcc gcgtgctttc ttataataaa gaaacaggtg cttttgaaga
     8161 attacagaaa atatcgacct tgccagaaga attcgacggt gaaaatggag gggcagctat
     8221 ccgcatttca aatgatggca agttccttta tgcttctaac cgaggacata actcgattgc
     8281 tgtattcgca gtttttgaag atggttccca cattcaaaac aagcaaatca tctcaacaga
     8341 aggggatttt ccccgcgatt tcgcactaga tccaagcaat aattttgtcg tgtgtgccaa
     8401 tcagaacacc gataatctga cattatatcg ccgtcatcct gaaacaggat tactggaatt
     8461 actgaaaaaa gatgtctatg taccagaatg tgtctgtgtt tattttgatc gttagtaaga
     8521 aaaggagaat gaaatgaatc agcaagacgt attagacaga ctacgggaag aactaaatat
     8581 tcctttcttt gatgggaaaa tcgaagataa agagtatagc gaagaggaat atcagaaact
     8641 caaagccgat ttacagaact actttgaaca atatgtacag aatgtagaaa actaatcagc
     8701 tttccatact atctgaaaag aacatcagga caagactttt ccgtctatcc tgatgttctt
     8761 ttctacaaat aaaaaaccgc cgagatggtt agactcgacg gaaaaggagt atttactcga
     8821 ttttgagtaa gtacaaggtt gttgttggtt ataggtatgt cattatcata aaggattttg
     8881 atcactctat cataaaggta atattacatt tatattagat aactctagtt tttattgtta
     8941 tcaaagattt cttttatttt ttcaacaaca aattagtcat tttttggatg gcagctgtca
     9001 attggtctgt cgcttggtct tgttttgctt cagatgtatt gaatagatct tcatctaccc
     9061 ctgattcaag atcgatactt tggatcattt cttcacagcc tgctacatat gaaagataag
     9121 ctttttcaaa atttttatga atgcccattg cttttgctgg tggacgcaaa gtactgactt
     9181 tcttaagcat tgcccgatat ttttttgttc cttcttcaaa taacaggatg atctcttcaa
     9241 gagtcgattt gtccagttca cttgtttttc cttcatcaat tgcgtttctg atcacttcat
     9301 atttcggatg cattccttct ccgattgctt ctgtttcctt gacgatttga tcgatggact
     9361 gcacataata gccaatattc ggtaacatgt tcgttttcct actttctcca ttgttgttat
     9421 tatttattct acttgttttt atcctcaaat gacaagtact tgaaaaaatt taatggtttc
     9481 tatacagctc gccattctta ttcgtgctca aagaaaccat ctgctaaact atattgtttc
     9541 cctgcgacaa tgtcatattg gatcaattga tattcgtcgt aaatctcttg ttgcgagcga
     9601 ttgaattgcg cttctttata ccactgtccg ttttgatagt acagttctcg ttcaaacgcc
     9661 ggaagttcct gttctaatga taaaagcagc tgataaaagc catttgttgt ctgattcgtc
     9721 tgttccatta gattcgctgc aaaataaaac ggactggtga ttgcatcgtg agtcgtttgc
     9781 ttttctaatt ctcctttact gtcgaacata agaaattgtg tttcatgcaa tgtttgtttg
     9841 tcattttttg cttggatcgt atctgaatag atccctggaa gatgatcccc ccaaaaaaca
     9901 actaaagtcc ttctagaaag attcttcaat tcttccgtga actgcttcag tgccgtgctg
     9961 ctataggaaa tatcttgcag ataattctct aagtcaagtg tcccacttcc atctgaagtt
    10021 tttgcaggat agtctagatt atcatacttt ccatcgtagg gcatatgtgt ctgcatcgtg
    10081 actaaatgaa tgaactgagg tgttttttct tccttgagaa gtgtcattac ttctttgtaa
    10141 gctgactcat cagaaatata tggattattc tctatcgtat ccgtataggt catcgtacgc
    10201 tcgctgatga actggtcaaa tcctaatgtc tgataaacat cctctctttt atacatcgaa
    10261 gtattgtatg gatggatcgc tgtcgtctgg tatgattgtg cgtttaacgc tgaaacgata
    10321 gaaggaagct gatccatttt tggtacaagc atcgtgtaag gggtggtgag ttgcgcatta
    10381 aataacgcca tagaaaaacc agtcaatgct tcaaattcga tatttgctgt tccaccgcca
    10441 tagttttgag aaagcatatt gccactatat gtttgatcag ctacttcata ataatctgcc
    10501 aatggctcac cagatacttc tacgccgttt aatcgactag gatctgagaa actttcactc
    10561 atcacgaaca cgatgttcgg cgactcttcc tctacagttt tatttttttc atcggctagc
    10621 ttctggtatt tttcagtgat ttctttgatc ttttctttcg aatatccttc aggttcatcc
    10681 attggttcta ccttcagatt gtacaaaaac ccaccgataa aaccagtgtt atagtagttc
    10741 attttctggc tgtaaggtat ccatagtgcc gttttattat atgcttttcg caacaaatta
    10801 tcgggattgt tgaaattact gatataccct agcagtccaa ttgccacaag cagtgtcgtt
    10861 aatcggatca attggaatcg ccttcctttt ttcaggcttc gaaacatgta ccagcaaaac
    10921 aatcctatca cggttcctgc ggcagctaag atcactgtaa acagcatagt gccggtcata
    10981 tctttcagca atccgatttc agtgatcatc ttcaaatcgt ctggataaat cggttcttgc
    11041 cgataactca ttttcatata atttgcaaaa cctaatacac cgatggctac gacatacgta
    11101 agggaaccta aagggacaga tcctgctagt gcaatcagaa aaataagaat aatcagcaag
    11161 acgagacagg ctaagaagaa tttttccgta tgccaagaaa aagcaaattt caacgcaagg
    11221 tctacggata gatcattttg acaccactgc aaaaataaat tactaaaaac aacaagaaaa
    11281 aagatactga tgattgctgc tgttcctttt aaaatctttt tctgtttggt cgaaagtctg
    11341 cttatatatc ttttcaaatg cttgctcctt catttctatc aataaaagaa tgttgcttct
    11401 cttattttag ttgtacgaaa ttcgaaagta aagaacggaa agaagaatta atgaaatcca
    11461 aatattctct ttctttatgg cctttctggt ttctttaata agcggacctt tcgtactcca
    11521 gaaatttttt ctagctgttg tttcacttga ttgagctgtt caaaatcagt actgtctatg
    11581 tcaatcaata tgtagacatg ctcattctta tggttacgcg atatatctgc gatcgctagc
    11641 tcgttctcat tcagcagaga aaatatctct gctaatatat tggttttctt ttgataaaat
    11701 atagtgaatc gaaacggcgc ttggaaaaac attcgtgcgg atggataatt gaccgcttct
    11761 ctaaccgtac cgaacaaaag ataatctttt aaggcttcaa ctgccaaacg tccgctgtct
    11821 gccaaagctt cctgagtcga tccccctaga tgaggcaaca taagtatacg gtcattttct
    11881 aagaactctt cttctggaaa atcagtcaag tatttagcca gatgttgttt ttccaatgct
    11941 tgcataacag catatttatc aacaatttca cttcttccta cattgataag tacagcatct
    12001 tttttcattt tttctatatt cgcctgatcg atcaatcctt ttgtatcttc tgtcaacggc
    12061 agcatgacta cgatgtaatc cgaggtagaa agaactgttt ctaaatctgc ttgccgaaca
    12121 taatccaact gggcatcgcg gatagaataa cccaagacat ccatccctaa gctatagcaa
    12181 cttagcgcta cttttgtgcc tatcgctcca agaccaagaa gaccgatggt tttgccttgc
    12241 aattctcgtc ccacataagc acttcttttg ttttctgcct gttctaaaat attaggacct
    12301 gttagtgttt gtaccatacg acttgcttcg attatcggac gggaagataa gagcaaacag
    12361 cacaaaacaa gctcttttac tgcattagca tttacacctg gtgtattcat gacgatcgtc
    12421 ccgttttcag aagctttttc aacgttgatc gtgttcaccc caacaccagc tcttgaaatt
    12481 gctagcaaat ctggtgtaag ccattcatct ttcactttcg tactacgaat aactattcct
    12541 tcggctggca aatcatctat tattttgaaa tattcccctt gtaacttttc tatctcttgt
    12601 tctggaatag catcaatcaa atgaacgtga tacataaaac cccctcctta ctaacaagta
    12661 tctcgaaatt tctgcaatta gacaactgtt taccatttga cttcctagaa gcaaaaagag
    12721 cagttagagc agagtaggct gagtgataaa aataaggcta tgacaagtta ctgccataag
    12781 ccttattttc gagagcaaaa tattgagggt gagatatctt gataaatggt gttccgttag
    12841 ctgacattga taataagact aaatttcaaa aaagttgaaa agcaaatttc gtcaatctct
    12901 tcttatttct taaaactaag tggctttttc acaacctctt tttatctaat aaccactgtt
    12961 tccaactcaa ctaattttgc ccacgtttca atttgatctg ttgttagatt tagcgagaca
    13021 acggtatgat gaccgccacc tgcctgaatc catgaatgga caccttcatg gaaattcggt
    13081 ttagttttcc ataacacacg tgcaacaggt aaattaggtg cttcagtcgt tggttcaaag
    13141 gcttctactt cattgatcag cagtttataa tgcgtaccga aatctgccat cgatacgact
    13201 accccttctc ctgctttccc atcaaataca agacgcgccg gatcttctct atctcccatt
    13261 gataaaggag aaacaacgat tcttggtttc gtcgcagcaa gcgtcggatc tacttccatc
    13321 atatgggatt ccaagattgc ttcttggcca ctagctagct cgtaagtata atcttccatg
    13381 aatcctgtat ctttccctcg agccatgatt ttcagcaacc gatcaatcgc tgcagttttc
    13441 cagtcgcctt ccccagcaaa accgtatcct tctgccatca aacgttgtac agctagtcca
    13501 ggtagttgtt tcattccata caggtcttca aaattagtcg taaaagcgtt atagcctcct
    13561 tcttctaaga aacggcgaat accgatttcc tgctgagctt gtacttttac atgttcctcc
    13621 catgtctttt cttcataatc accatagtcg aaggtataca attccttgta ctcttcaaat
    13681 aattgatcga cttcttcgtc tgatacgcga tcgattactt gtacaagatc tccgatacca
    13741 aaataatcaa cagtccaacc aaattgaatc tgtgcttcca ctttgtctcc ttctgtgaca
    13801 cccacgtttc tcatgttgtc accaaaacga gccactttta ttccaaaact ttcattatag
    13861 gctactgcaa catccatcca atcagcaatc tctttttgga tctcaggtcg tttccagtag
    13921 ccaacgacga ttttattttg tttatttaat cgagcattga tgaacccata ttcgcggtca
    13981 ccatgagcgg attgatttaa attcatgaaa tccatatcga tcgttttcca aggaatgctt
    14041 tcgttatatt gcgtagctaa atgaagcaat ggtttttgta gaagctttgt cccgcggatc
    14101 cacatttttg ctggtgagaa agtatgcatc caagtgatca cacctgctac ttcttctcga
    14161 taattgacct ctttcatgat ttttgtgatc gtatcagcag taactgctaa ttcttgaagg
    14221 cggattggat aaggcaattg gccattttca ttcagttcat cgaccatttc ttgtgcatgt
    14281 ttctttactt ctcgcagtgc ttcttcccca tataaatgct gtgatcctac aacaaaccaa
    14341 aattcttttt ctccaatatt caacataatt agccactcct tttatttgtt ttgtccgtaa
    14401 tacgcatttt ttccgtgttt tcgtaaataa tgtttatcta aaatccgttg aggcagctct
    14461 tctgaaaatg aattgagctg tctggtaaat aaattcatct tgcatacttc atctagtacg
    14521 actgcgttca ttaccgcact ttgcgcatct ttcccccaag taaatggacc gtgtccgtgt
    14581 aaaagtaccc ctggaattgc taagggatca attttgcgtt ctttgaatgt ttctatgata
    14641 acttttcctg tttcatattc gtacccgctg tcgatttcct gttgtgtcaa aaatcgagca
    14701 caaggtaccg atccataaaa agtatctgca tgcgtcgtcc ccatcgcagg aacatccaat
    14761 cctgcttgtg cccagatcgt cgcccatgtc gagtgagtat ggacgattcc tccgatttga
    14821 ggaaatgaac gatataaaac agcatgagta ggcgtatccg aagagggatt gagtttacct
    14881 tcaatgatat gattgtccaa gtccacaacg accatgtcgt ctgctgtcat ctcttcataa
    14941 ctgactccgc taggtttgat aacgaaatat cgtgtttcag gatcaaaagc gctcacattt
    15001 ccccatgtat atttgacgag tccgtgttta ggcaagtcaa gatttgcttg gtatacttct
    15061 tctttcagtt gttccagcat tttctatcac tcctttttct tgcaattgat gaatcgctgt
    15121 tttttcaatg tcgatcccct cacggtaacg tctcataaat atctgatagc ctgctatttc
    15181 ttctgctgaa ggtgtgatgg tgattccttg gtcttgtcca aacacgtctt ctgccaagaa
    15241 gttttctaaa gacttcccat gtcgatccat catataggct gctaataacg cgattcccca
    15301 cgctccacct tctccggctg tgtccatcac tgtaactggt gcctccatag cagatgctag
    15361 aatccgctgt ccaacttctg gtgttttaaa aatcccccca tgccccacta aacgatcaat
    15421 ttggacattc tcagatttca atatatccat tccgattctc attgcaccaa aagcactggc
    15481 taaatggatc cgcatgaaat tcgctaaatc aaaacggcta cctggtgtac gtacaaataa
    15541 tggccttcct tcatttactc ctgtaatgtt ttcaccggaa aaataaccat aagaaagtaa
    15601 tcccccgcaa tccgtatcgc cttctagcgc tttgttgaat aataccgtga ataatttatc
    15661 tctgcttatc tccataccca aagaattggt aaattcttca aaaatactga cccaagcatt
    15721 gatatccgaa gagcagttat tcgtatgaac catgcctact agttctcctg aaggtgtagt
    15781 gaccatgtcg atttccggat ggacattttc tagttctttt tctaatacga tcatagcgaa
    15841 ggcggaagta ccagccgaaa tgttccctgt ccgtttggct acactgttcg tagcgaccat
    15901 accggttcct gcatcccctt ctggcggaca aaccgggatt cctggtctca aatttcccgt
    15961 agggtcgatc agataagccc ctgattcgct taacttgcca gcttcttctc ctgctactag
    16021 aactttaggc aaaatgtgat ccaagtcaat cgctacgtgc gctttttcga ttaactgacc
    16081 aaaaatattt ttcatttctt gatggtaggt tttcgttgaa ggatcgatag gaaacatgcc
    16141 tgatgcatct cctacgccta gtactttctc accagtaagc tgccaatgga cataacctgc
    16201 aagcgttgtc aaaaaattaa tttctttcac atgttcttct ttattcaaaa tagattgata
    16261 caaatgagcg atactccatc tctgcggaat attgtattga aatttttccg ttaatattcg
    16321 ttctgcttct tcagtgattg tatttcgcca agtacgaaat ggtactagta actgttcctt
    16381 gctatcaaat gctagataac cgtgcatcat tgcactgaac ccaatcgacc cgattgtcgt
    16441 aagattctcg ccatagattt cgaatacttc tgctgccatt tttcggtaac tgacgcgcag
    16501 tcctttccaa atatcttcta atgaataggt ccagatacca ttttctagtt tgttttccca
    16561 ctcataacta ccagcggcaa taggagtaaa agatgaatca atcaatacag ctttgatcct
    16621 agttgatcca aactcaatcc ctaaagatgt acgaccatct atgacatcta acatactttg
    16681 cgcatttact tccttcataa tgatttaact ccctccttct cgtcaaacct gatcaaaccg
    16741 tctttttagt agcgcttaca atgattattg tatacttttg tacgtacatg tcaagcggtt
    16801 atttacaaga atacaataaa aaacacttgt tttgtacgta cataagttat aaaatgaaat
    16861 tgcttacaaa atctgatcaa ccgccttctc gaaattctag aaggagagaa tacttatgaa
    16921 aaaagaaaaa aaagtttcct catcgtttat ttattttttt ggcgcatttg gcggcattct
    16981 atttggatat gatattggtg ttatgaccgg cgccttacct tttttacagc atgattgggg
    17041 tttggcaggt aaagcttctt tgataggatg gatcacgtct tcggtcatgt taggtgcgat
    17101 ccttggcggc tctttatctg gtcttctttc tgataagctt ggacgacgaa aaatgattct
    17161 tctttctgca cttattttta tggctggttc tgtcctttct gcatctgccc ctcacaatgg
    17221 ttcttatttt ctgattgcag caaggattct tctaggttta gctgttggcg ctgcatctgc
    17281 cctagttcct gcttatatgt ctgaaatggc tcctgctaga ctaaggggaa gattgtcagg
    17341 gatcaatcaa gtgatgattg cttctggcat gctcctttcc tatgttgcag attatttgct
    17401 aaaagtgttg cctgaaacga tggcttggcg cgtgatgtta gggctcgctg ctgtccccgc
    17461 gctgatttta tttttcggtg ttttagctct accagagtca ccgcgttttc ttatgcaatc
    17521 tggccgcttg gaagaggcaa aaagagtatt gaactatatt cggacaccaa aagaagctga
    17581 acaggaattc gaacaaatcc agctgaatgt caaacaagaa aagacaaccg gaacttcttg
    17641 gcatactttg tttttagaaa aatatcgttc cttagtcatt gccggtattg gtgtagcagt
    17701 attccagcaa tttcaaggag ctaatgctat tttttactat attccgctga tcgtagaaaa
    17761 agcgactggg catgcagcga gcgatgcatt gatgtggccg atcatccaag gaatcatttt
    17821 agttgctggt tctttgctct ttttggttat tgcagacaag ttcaatcggc gaactttatt
    17881 gaaaataggc ggtagcgtga tgggactttc attcatccta ccagctgttt taggaactgt
    17941 actggatgct catacaaatt cgttgttgat tctcttgttt ttatgtattt atgtcgcatt
    18001 ttattcttgc acatgggctc cactgacatg ggtaatcata ggcgaaatat tcccactagc
    18061 tgtccgcggg cgagcatctg gcctagcctc ttcttttaat tggattggtt ctttcctagt
    18121 tggcttgctt tttcctgtga tgactgcttc tatgtctcaa gaaatcgttt tcggcatttt
    18181 tgggatcatc tgctttttag gggttttatt tattcaagag atcgtaccag aaactcgtgg
    18241 gaaatcttta gaggaaatcg aacaaagtgc atctaaaaaa acttatccta aacgtatttc
    18301 tatccatcat tcttaaagag gttgtgacag aagtggtcag cttcaagaaa taagaaggaa
    18361 ccgcttagtt tccagtcaca aggaacaatt tcaaaaaaca gcttctcatg tttgatgaat
    18421 attgtgactt gtgaccagtt ggtaggagaa caccgtttag tggagaggtg gtgaaagaaa
    18481 cgttcagcct tgagcgatga caaaagctct cacaaacatt gcgacgagta accgtaggag
    18541 caataagagg cggtaaaaac ccgtctctta tttttcgttt tctttcactg tttcccgttc
    18601 aactagtaca ggttcataga gaatatttgg ctgtgcctgt cctttttcaa tcgttgtgac
    18661 gatccaccgt gcggcatctt gtcccaactt ttcttttgga tgcgtcaatg ttgtcaattt
    18721 tttattccct aaatggctta aagaagaatc gtctgttcct acgatcgata ggtcatctgg
    18781 aatatgatag ccattttctg tcaacttatc tagcattaaa ctagctattt gatcgttata
    18841 gcaaatgatg ccatctaaag cttgttcttc tttcaaccgt tgtactgttt tttcagcgat
    18901 tgtttctcgt gtttccgtgg tgaaagtaat gatatcttcc gtcaaaaaac gcacattata
    18961 ctgttcacac gcgctgataa aacctttcat cctgtatttt ccttgaagat cgtcgatttt
    19021 tgtgatgaac aacagacgct gatgtccttt ttttatcaaa tattctgctg ccataaaacc
    19081 gactttcaca tcatctaaac aaatataaga ggcatttaac tcttcataag cagcattgat
    19141 catcaccatc ggaatgcctt gttctctcaa agcaacataa agtgctaagt ttgggttata
    19201 ctgattactt ttcgtaggct caacgatcaa accatctacc ccataagcaa tcattttctt
    19261 caaacactct ttctccaatt cgtgatcgtt attcgtactg gctaaaagca atgaataccc
    19321 agattctcgt aattcatttt cgattcctcg gataatcgac ggaaaaatat aatcagagag
    19381 atatgtggtg atgacaccga tcgtttttgt tctgttcaat ggtgtttttt ctttcttata
    19441 gctgtcatct acatatgtgc ccgacccttt ttctttacgc agatagccct catttaccaa
    19501 cacagcgatt gcttgccgaa tcgtatgtct gctgacgtca tatatttctt gcagcttgaa
    19561 ttctgaggga atggttgtat ttacttcgta ttcctcacga aggatctttt gttttatctc
    19621 ttctgcaata tcttgatatt ttgccatttg ccttgcccct ttttatttgt acgtacatat
    19681 atcataacga gtctgcaagg tttattcaag caaaaatcaa ggtttcttgt gctcataagg
    19741 catacggaac aggttcacca aattctggaa atccttgctc attccacgta aagcattgcg
    19801 cgttcgcgtg ccgattagga ttgtctaacg gatccccttt ttggttcttc tctggtcgag
    19861 catgatagat caaaatatca aagcacccgt cttctgaaac cgtaaacgag ttgtgaccag
    19921 gaccaaattg cttatttttt tcagaagaaa cgaatactgg ctccgataat ttatgccatg
    19981 attcttttaa taaaagattc ttgtgctcat cagcccacag caggcccatg gcatagtttt
    20041 catctgttgc actaccagaa tacgtaatga atattttccc attgcgagta aggactgctg
    20101 gaccttcatt tactgaaaaa ccccgttttt cccattcata ctcaggtata gaaaggagga
    20161 tctgcttccc ctttaacgtc caaggattat ccatttcgga tagataaaga ttagaattcc
    20221 cagtaatttc aggatcttgt tgggcccaca cataatatag ctttccttga gaagagaaag
    20281 ttgttccgtc taaactgaaa gtttcccttt tcgtttttat ttgtcccttt tctatccaat
    20341 ctgtattcat tggatctata tgctgatttt caagtacgaa catgcggtga tgatgagatt
    20401 catcacgtat agttttatga ttgcttgcag caaagtaaat ataccatttt ccattgatat
    20461 aatggacttc aggtgcccag atcaattcac tcatcggtcc ttcttcatga gcctgccata
    20521 caatcaggct tgcagcatgt tctaattcat tcagtgactt tgcccttctt aattcaatca
    20581 cttggtagcc tggaaccgat cctgtaaaat aataataacc atctgtatgt ttatataccc
    20641 aaggatctgc ccgttgccga acgataggat tattataaag tgtcttcatc ataacaaatt
    20701 tcctcacatt ttctttattc taattacatt ccaagagtat ttttctatcc ctacatttaa
    20761 ttcgtcatgt ttttctattg aaaaatagtt tatttcaggt tttatttttt ctggttcttc
    20821 acgtgtattt ttgtccaaca gatcgctact ggttaatgtg tagtgctctc cttgatctag
    20881 caaattgaaa tcatgttcaa tcgttatctt ttgttgttca tttgtgcgat tgatcaagaa
    20941 aatagtcagc tgattgccgt tatctacgat cacactgtcc acataaggaa cattttttat
    21001 cttttcacaa tcataaacag ggcaaatgat ttgttgtttc aatacttgac ctttagcata
    21061 tttcgataag tgttgcatca cataataagt tggattcctc catgcttgtc ctttagcatc
    21121 tgtcagtatt aaaggtattg tgtttactaa caatgattga caactaatct ttacgcgatc
    21181 tgcgtgtcgt aaaatagcca gccctaatga accaaataat aatgtatctt ccatagtaaa
    21241 gtaacaccaa tcgatgggac taccgacttc aaaatcccta tgtctttttt ccggttgggc
    21301 atgtacattc cattcatcaa acgctagata cattgttttc tcacttctca aatatccttt
    21361 tacataatca caagtagcaa cgatttcttc aatttgacga tcgaatcgat aagcttttgc
    21421 aaggtatgtc gctgtatcat cacgctcatt tttaggaggt ttagtcaagt cttcttcatc
    21481 atacttatca atatagttat gcaaagctaa ataatctaca ttctcataag cttcttctaa
    21541 tgcgatacga tcccattcag ggtacgatgg taaacgtggc gtagagcttc caactaagat
    21601 tgtttcaatt gaatcatcca ctaacttcat gacttttgag gcttcatttg ctaacctacc
    21661 atattcataa gcactcttag cccccacttg ccatggaccg tctagctcat tccctaaaca
    21721 ccataattta acgccaaaag gctttttttg cccatttttt attcttaaat cactccagaa
    21781 ggttcctttt ggaaaattac aatattctac taaatttttt gcttcatcaa ttccttttgt
    21841 tcctaaattc accgtgaata tcggtttcgc ttgtacatga ctgatccatt taaaaaattc
    21901 gtggagtcca aaagaatttg gttctatacc tcgccatgct aaatcaattt tttttggtcg
    21961 ttgttctttc ctacctacag tatccaccca atcataacca gatgtaaagt ttcctccagg
    22021 atagcgaatg acacctaatt ctaattcctt tacataagag aggacatctt gtctaaaccc
    22081 gtcaccatca gctgtttcat ggcccggttc ataaatccct gtatagacga cacttcccat
    22141 atgctcaaca aatgagccaa acagccgaga actgatctct cctaccgtaa aatcctctct
    22201 gatttttact ttcacttctt cgtccaacag ctttccctac ctttcatttc ctatagtcaa
    22261 gataatagat acaagtttcc atacgccacc agcaaagata aaaataaaag gagggaaaag
    22321 aaatatgagc agtacaaatc ctaataacaa tacgcaacaa agaatatttc tcaaaaaatc
    22381 aaaaaatact ttccatgcac tttgttcaaa aatttgtaaa aatgtgatat ctttgttttc
    22441 agaaatcaca tatatccagg ataaaagaaa catggaataa ataagtaaaa ctacatatcc
    22501 actaattgaa agtacgattg tctgttcttc taataattga ttaacaagaa aataaataat
    22561 gatcgttaac agactaagga acaagttctt accaaaatgt tgctttattc cttgaaagaa
    22621 aaaataaatg atatttcctg atccctcacc tttccattgc gccattacat aaaaaacagc
    22681 acatgtagca ggcacgatag taataacagg caaacacacg attacccaga gaatacctaa
    22741 taagatgtaa tcagaaacca caatcaactg tccataaaat ttagtctcaa ctattttcat
    22801 cttcctcact ctttcattcc agacatagct gttccttgaa caaaatattt ctgtgcaaaa
    22861 atataaacca ctagtaatgg cagcattgaa ataaccgttc cagccattac aggtccataa
    22921 aaagaaatgt tctgccctgt aaataaagct aaccctgctg gtaaagttct catttttgaa
    22981 ctacttgtca atatcaatgg ataaagcaag tcattccaac tattcatcag cgtgaaaatc
    23041 cctaatgata aaagagtagg tttgctcaat ggcaacatga ttttcaaaaa aatattaaac
    23101 tcacttaatc catcaatgcg tgctgcctct tccaaagaat ctggtaaagt aataaaaaag
    23161 gaacgcatca tgaagatacc aaatgcagtt gtcatacgag gaatgatcaa acctgcataa
    23221 gtatcaagca tgccaagcaa attgacttca ataaatagag gaatcatgaa gacttggaat
    23281 gggatcatca ttgtcagcaa aacgaaatag aacaaaactg attttccttt gaaacgcata
    23341 cgagcaaatg cataccccgc aagagaatca aagaatacag aagtgatcac tgtccctcca
    23401 gcaaaaatca ctgtattttt gatgtaatct aataaaggga tcgttgtcca aaccttaata
    23461 tagttatcta gggtatagct atctgcaaat attctaggcg gaaatgagat aatgtctttt
    23521 tcgtgtttaa aagaagaaat aatcagccac aaaaaaggaa acgcaataac caacaatata
    23581 actagcatac taatcgttcg aatgattttt ttaccactaa ctgcttttcg actattcaca
    23641 gtaactgtaa tcgagctttc tggtgccata caggtttccc tcctatttca tttgtttttc
    23701 tttccgtgac atgtacacat tagtggagat agctatagtt gcaacaatga taaacaaaac
    23761 cgaagacagt gctgatgcat agcccaattc ataaggtgct gtaaatcctc gactgtaaat
    23821 atattgaaca gctgtttctg tcttaaattg tgggccacca gcggttgcaa catatacttg
    23881 gtcaaacact tgcatcgaac caatcagatt cgttaaaata caaaaaccta aggagggaac
    23941 gatctgaggt agcgtaatgt taaaaaactg ctgtcgattt gttgcaccat ccatttgagc
    24001 agattcatac aaagagggag agattccctg aatagcagtc aagagaatcg tcatagtaac
    24061 accaaaattc ttccaaacag tcatgatggc taccgtcggc atagcaaggg ttggatcgcg
    24121 aaaaaattga gggatcggca agccgacttg tgaaaacaag taaggaatcg cccctacatt
    24181 cggatcaagc aacatagaaa aaataatcgc aattgacgtc aatgaacaaa taactggaat
    24241 gtaaaatgtc gaacgacaaa aacgattgaa tctggtattt ttagataatg ctactgctgc
    24301 taataaacca acgataattt gtgttggcgt ttcgagtacg gtgaaatata aagaatgaat
    24361 caacgaatta actgctcgtt catcactaaa tatacgtgtg aaattttcaa aacttacaaa
    24421 atttcttgat gtaaagaaaa tattcaaatc tgtaaaacta atagcaaatg ttcctaaaag
    24481 cggtatgaca gtaaataata ataaaactaa aaaagatgga gttaaaaaca aatacgcagc
    24541 acgatcagga cgattccaat atttggtgaa tccgttcata tagtccacct catctttcat
    24601 tttgataaaa tatacaatct tggtttaaac gaatctgaat aagatatccg aacaatcgct
    24661 gtgatttttg caataacacc tatctgcaaa tactaggtcg atcattcaga tatctgtatc
    24721 ttgccaacag tctatcctgt ataaagttct gtactatttt tgcagtaatt gattgatggc
    24781 atcatctgca tcgttcatga gtgtctcagg atcttctcct gctaataatt tttcaatcag
    24841 tggattgatg atatcgttat tgatcgcaga gatttgggta aaacctggta aatatggctc
    24901 tgcatagtcc atttgtttcg ataattcaga tacaatagga tcatttttta cttcttcatc
    24961 ttttgctact gaatccaagt aggcaggaaa accattttcg atactccatt ttttaccaat
    25021 ttcagttgta ttccaatatt tcaaaaactc atagacagct tcttttttat tattatctgt
    25081 acttgccgga atggcatatc ctacgccatc taaaatagct gtttttttgt ctgaatcact
    25141 cccttgtggt aaggtagtca cattataatc aatctcgttt gctttcaatc cgttatttaa
    25201 ccatggccca ttgatttcaa tggctagttg accagcattc attaaattgt ccatttcggc
    25261 gccagaaatc gattctggac cagtcttgtc tacatggatc attttttgga tcgcttttaa
    25321 cgttttaagg ttctcaggag acgcaaattc agacttagta taatcatcgt tcactaattt
    25381 accgccattt gctaacatcc agttatataa cggtgcagtt ccatccttat tgaagacaaa
    25441 acctgataca tttttactac tatcagttaa ttttggtgcc atttctgtca attcttccca
    25501 agtagtaggt ggttgttcag tatctaatcc agcttgttta aacaaatcat tattccaata
    25561 catatacatg ccttgtacct gcatggggac aaaatactgt ttaccttcta cttcacctaa
    25621 ttcaatagcc gtttctttaa aatcagattt atctactcca tcatattccc agaaatcgtc
    25681 taatggttgt accgctccgt tttctacata ctgtgcaaaa tctggataat ttaatgcaat
    25741 aaagtcaggt gcttttttag aagaaatcgc tgtaggaagt ttttcattca aattggccca
    25801 agtcatgata tccatttcaa ttttgatgtt tttatcattt gttttattaa attcattaac
    25861 gatttcttgc aatatttcac catcagatgc agtaaaccca ttccaaaaag tcaaagtcac
    25921 ttctttatca gaatcagatt ctgctgaact tccgccaccg caagctccta aaatacctgt
    25981 tgcagctacc aacaaagagc caattaacca ttttttacct ttcatttttt gttcctcctt
    26041 catctgataa acgacatctg accacattcc aagatagcgg tttcaataaa caattgattt
    26101 tcccatcttc agcttttaca tttgttgaat gacttggttt tacttgttca cttttaggaa
    26161 gattagttgc ttttgtatca aatccactca tttcagaaaa atcaatcact ccctctaatg
    26221 ataattcaga caagtgaaca gttagattca tttcttcttc tccacggtta actgcaaata
    26281 tgacaagttc tttgtcattt attacggcta tactttctaa atacggcact tcttcaaaat
    26341 cttccgtcgc atagtttgct gaacgaattt gtgggcttaa cacctctcct tgtccataca
    26401 cagcagcttg cataaatgga taatagatcg tctgtctcca agcttctccg tttgtttctg
    26461 tcctgattgg tgcaataacg tttaccaatt gagcaagaca agcaatcttt actctatctg
    26521 catgtttcaa taaagtgatt aatagacagc ctaatagtaa tgcatcttca aaattatagt
    26581 tatcttctag taaaggagga gcaatctgcc aaggcgctgc ttgctcatct tgttccgctg
    26641 aatgatacca aatattccat tcatcaaagg acaggttgat ctgcttctta ctatgtttct
    26701 tcgccttgac tgtatcgcac atcgctgtca cttcagaaat gaaccgatcc atgtctaagg
    26761 aacgtgcaag ataatgagaa agatcatttt tttggttgcc ataatattga tgcagagaca
    26821 aataatctat ttgatcgtac gcttgatcaa gaactgttaa ctcccaatca ccaaatgtag
    26881 gcatttgccg attcgaactt ccgcataaaa ccacctcaat tgaatcatct acgagtttca
    26941 tcgccttagc cgtttcctct gctaaccgtc catattcttc cgctgtttta tgtccaatct
    27001 gccaaggacc gtccatttca ttccctaaac accatgtctt aattccaaaa gggctctctt
    27061 gaccattcga acgccttaaa tcactccaat aagttccttt aggaaaatta caatattcga
    27121 ctaaattacg agctgcatct actccacgag tacccagatt gacagccata ttgatttcgg
    27181 cccccacatg ctgacaccag ttataaaatt catgaatccc aacttcattc gtttcaattg
    27241 tccgccaagc taaatccaac cttctaggtc tatttgctat gggcccaata ctgtcttccc
    27301 aacgaaatcc tgacacaaaa tttccaccag gatatctaat catgggaatg ttcaattctt
    27361 ttaccaagtg aatgacgtct tggcgaaatc cacttttatt agctgatgga tgatctggct
    27421 gataaatccc ttcatatact gctcgtccca tatgttcaat aaatgaactg tacaaccgcg
    27481 gatcaacttt gcctacacgc ttgacactac taatcaacat tgtggcttcc ataactgacc
    27541 tcctttaatt tatacatgaa taatacacct cgttgaaagc gttgtcaata atataaatgt
    27601 taaacttact tattttttat cgattttaat taaccaaaat attaataatg attaaaacaa
    27661 ataatttaat ataactttta ttaacaaata tgttaatata taagaaaaac cttttaagag
    27721 gtgatatata tgcaactaca aataaacgaa gaatccttac cggtatatga agcattagct
    27781 agtaaaacaa ggatcaagat catccagcta ctttccaaaa aaaagatgaa tgtcaaagat
    27841 ttggcaaaag aacttggagt gagcagtgct atcacgacga tgcacgtgaa aaagctagag
    27901 gaagcaaaca tcatcaaaac agaaaaagta ggacaacaaa aaatttcgag ccttcgtgtc
    27961 gataaaatcg atattagttt tccagaaaaa atattcaatg cttttgatac gaaagaaaca
    28021 tcgataccta ttggtcacta tacaaattat gcaattgaac caacatgcgg tttagctacg
    28081 atccatgatt ttatcgggaa agtggatgaa ccacgctatt ttatggatcc tcgaaggatg
    28141 gatgcccgca ttctctggtt taccagcgga tttgtcgagt atcaggcacc taatttttta
    28201 aatacagagg atacattgga gatgttggaa gtttctgtgg aaatttcttc tgaatttcct
    28261 ttttcaaatg acaattggcc ttcagatatc actttcagcc taaatggtgt ggagctagga
    28321 acatggacga gccctggaga ttttgctgat atccgcggta aatatacgcc tgattggtat
    28381 ccagataatc ttaatcaata cggcttgctg aagacgatcc gaattaccaa acacttgacg
    28441 aatatgaatg gagaaccctt gtcaaacatc acgatcaacg acatccctaa agagcaagac
    28501 acttggcatt tgcgaatcga agtgaaagac gatgccaaac atgtgggggg ctgtacttta
    28561 tttggtaaag gattcggtaa ttacgatcag gatatcaaat taaaagttta ctacagctga
    28621 tatttttctt ttctatttta taaaacaaaa acagccaatc cctatgaagg gacggctgtt
    28681 tttgctttat tgttatttcc agaaatcatc caaaacggaa attggcaaat gtcgtttatg
    28741 ttgtgtcttg ttccaccatg cttcgatttt ttcttgtgct tgagcgggaa cttcttttcc
    28801 ttctagataa tcatcaattt cattatatgt gacacctagt gcgacttcat ctgcaatcat
    28861 tggtttccca tcttcaagat ctgcagtcgg aatttttgtg tataattttt ccggtgcatt
    28921 caatgcttga agcaattgtt tcccttgtcg tttgtccaaa cggaataatg gcaaaatgtc
    28981 ggctccacca tcaccaaatt tcgtgaagaa tccagtaatg ttttctgcag catgatctgt
    29041 ccctaatacg gctcctgctc tttctccagc tacggcatat tgcgtaatca tacgttgacg
    29101 tgctttgata tttcctttgt taaaatcgct gattcccaca cctgcttcgc ttaatacttg
    29161 tacttgtgca tcaacagctg gtttgatatt tactcgcaga ctaacatcgg gctggataaa
    29221 gtcaagagca gcttttgcat cttcttcatc tgcttgttca ccataaggaa gacgaacagc
    29281 gataaattga tagttttcat cttttgtttc ttcacgcatt tcttccatcg ttagttgcgc
    29341 caaacggcct gctaaagtag aatcttggcc gccgctgata cctagtacaa aagttttaag
    29401 aaacggatat tttttcaaat atgctttcat aaagtcaata cttttacgta tttcttcttt
    29461 tggatcaatt gttggtttga cacctaattc attgataatt tctgtctgca ggctcattta
    29521 ttctcctcct atgcttctgt atgaagttct gctacgcttt ttttcattcg ttccatgata
    29581 gccattttat ggttccagca ttcagtagac agatcgactg ggtatttttg cggattcaag
    29641 tctcgtttat actcttccca tagtgaatct agattttctt ttgtatattc tttgatttcg
    29701 tttagtgcag gtaattcgta aactcttttt ccttcgataa agatatcttg taaaactggg
    29761 cgagctgtaa agtctcgaac agttttattg ataaacgtat gcactggatg gaacatgaag
    29821 atagcttctt cttctcgagg gtcttcatcc cataatgtca cgtagtctcc ttcagatttc
    29881 ccatcaaaat ttcgagtgat gcgccacact tgttttttcc ctggagtagt tactttttct
    29941 gcattgcttg ataacttgat cgtatccatc atttttcctt catcatcttc gatcgatact
    30001 agcttgaata ctgcaccaag ggctggctga tcataggctg tgatcaattt tgtcccaaca
    30061 ccccatacat caattttagc tttttgcatc tttaaattca aaatcgttgc ttcatccaag
    30121 tcattcgaag catagatttt tgcttccgta aatccggctg catctaattg ttcccgaaca
    30181 cgcttagata tataggccat atctccactg tcgatgcgta cgccttggaa gttgattttg
    30241 tcacctaatt ctttcgccac gcgaatcgca cttggcacac ctgatttcaa cgtatcataa
    30301 gtgtcgacta agaacacgca gtctttatgg gttttagcgt aggccataaa tgcttcataa
    30361 tcatttccat aagattggac taacgaatga gcatgggtcc cgctagctgg tatcccaaat
    30421 atcttcccag cacgtacatt gcttgttgca tctgctccgc cgatatatgc cgctctagtt
    30481 ccccagactg ctgcatccag ttcttgtgcc cgtctagttc caaattccaa tagtggatct
    30541 tctccgatga cagatttgat acgagctgct tttgtcgcga tcaacgtttg gaaattgacc
    30601 atattcaaca gtgctgtttc tactaattgg cagtgcgcta aaggcccttc cacttggatc
    30661 aatggttcat ttgcaaaaac tagttctcct tcacgagcag aacgaactgt tgctttaaat
    30721 tcaaaatttt gtaaatactc caaaaaacct tcaggataga cttctaatcc acgcaagtaa
    30781 gcaatatcgg aatcattgaa cgtcagattc tctaaataat tgactaaccg ttccaatcct
    30841 gcaaaaaccg cgtatccgtg gttaaaaggc atttctcgaa agtaacattc aaaaacagca
    30901 tgtaaatcag ctcgacctaa ttcccagtat gtctgcatca tattgatttg atatagatcc
    30961 gtatgcagcg tcaaactgtc gtctgggtaa gtattattca tcttgtatta ctcctcttgg
    31021 caagttttca tttcctaccc attataacaa aaaaaattaa taggaaaaga aatcttccat
    31081 tttttctgaa aaagcacatg ttttacggat atttcttgct aaaaatgaac tccatctgct
    31141 aaaactatcc tttcttattg gtatttaacc taaacgagaa agaatactta ttttattcaa
    31201 tgtatccgag acacgaagaa attagcgttt tctatttttc ttacttgata aaataagtag
    31261 attttcctac tacaatcgta gccgttaaga taccgatgat tgaacaaata taaccaaatg
    31321 tctctacaac ataatcaatg gcaaaagttt ttgaagcaat aatacgtctt tccttttttg
    31381 cttcttatcc ccaaagaaac ggatataact tattatgtat tgaatttttt tggaaaggcg
    31441 aattatgaca agatatacct tgcgttgaaa aaactcgcgg aaaaaatatc acacgttttt
    31501 aaaaagatac aaagtaagaa agcagctgtc aatagaatgg aaacaaaaat ggcgagacat
    31561 caatcagtct cgccttgttt tttattgtat acattagata tggagcaggt taccataaag
    31621 atgattatta gtcgttatta aatagaatcc ttcgtatttt tttgttctat cactacaata
    31681 tctttatttg gacgtttgaa ttgtattccg gcacgttcta gctcctgttt cactcctaca
    31741 tggactttga catcttctcg tgtcattttt aaaacgtgat gaatcgcata gtcgatttct
    31801 tgccttgtga tttttttctt cgtattgatc atcacgactt gctttttatc atatgtgtct
    31861 accaatagca gttgtgttcg atctaacgaa aataatttgt aataattaat agccgtattc
    31921 ccaaaaaaga attccactac tttaggataa aatgtcttaa tatttaaatt actattcaca
    31981 ggtgtttcga ttagcttcat ctcattcctc ttttctatat agtcgattta gatccaatct
    32041 taagttatgt taccatcttt cctagcatta aggaatcggt tacaattgaa cctttaaaga
    32101 caaaaggatt taccttttat cacttaatag tataacataa tttcatgaga aaaaaataca
    32161 attttttctt gaccatctcg ttacgtaaag gattatgctt acatttgtca ggaggaaaaa
    32221 taatggagta cacaataaag aaaatgtcag agatatcagg agtcagtccg agaaccttgc
    32281 gcttttatga tgagattgga ctgctaaaac cagctaggat caattcttca ggttatcgga
    32341 tttatggcaa aaaagaagtc gatcgtctgc aacacatctt attttatcga acaatggcat
    32401 tcaagttgga tgatatccaa gaggtcttag acaatccatc ttttgaccac cagaaagctt
    32461 taatcaagca tcagcaaatg ttgctggaaa aacgggcaca aatcgatacc ctcttgacaa
    32521 ctgtccaaca gacacttgat atgtacgaag gaggaagaaa aatgagtgac aaagaaaaat
    32581 ttgaagggtt taaacaacaa aagttgaaag aaaatgaaga atcctatgga caagagattc
    32641 gacaaaaata cggaaaaaaa aaggttacag catccaatga aaaatggatg aatatggata
    32701 aagaaacgta tgaagaaatg caaactgttg aaaagcagat gttatttgat ctcactcttt
    32761 acttaaaaga accagaagat gaaagcttag cagaccgtat cttccaagct cataagaagt
    32821 ggttatctta cagctggcct gaatatcagc caaaagcgca taaaggacta ggaatgatgt
    32881 acgaagccga tgaacggttc actgcatatt atgacgagcg aagtggtcat ggtgcagcaa
    32941 aagctttaaa tgaaattatc caaaaaaagg cgtaatcttt tacatgatcc aacaaaaaag
    33001 tacacgtaaa atgacctaat aacaaaacag cagacaccca agttagattt ttatgctaac
    33061 ttttggtgtc tgctccattc tttcacaagt tttttcatcc tactttaaat atattcatcg
    33121 ttgaataaac gtataaggta ttttcacttt atcctttttt tctgtaagaa acaattgaaa
    33181 tgccatttct ccgcaagctt ccagatggtg gtcgatggtt gggaaaccaa gaagctcgct
    33241 gatcagcaaa ttatcgcgtc caatcaccac tggtgtctta tcttgcagat agctttgcaa
    33301 gatgcctgct gcaaccatat ccgaatttgt aaagacacca tcaactccaa gctctttaaa
    33361 aaagaagcct gcttgttttc ctttctctgc atctatacaa tcccaaaaaa caagtgattc
    33421 atcaaaagat ggaaaaagtt gatgacatag ctgcaaagtg atttttgagt tataacttag
    33481 cctgccactt cgccccaacg tgatgcccaa ttgctttata ccttgctgct tcaaataagt
    33541 aagaccttct gtaattgatt gttctcgatc aataaagaca cagcttgcct gttttccctt
    33601 gatttcttca caaaaaacta gaggtccata tttttgatat gccaataaat catctagtgt
    33661 attggcacga gacgtaatga tcaatccatc gaaagcttta gctgcaaatt cttcaagata
    33721 ccttcgctct ttttctttct gatagcccgt cggtaaaagt gtcactttgt aatcataatc
    33781 aaacgctgct tcaatgatcc cactgatcaa ctgatcaaaa tacggatgat tggtataagg
    33841 cagaatcact ccaatgcttt tcgtttttcc ataacttaac tgtctggcat ttgcattagg
    33901 gatataatcg acttctttca tgaccgcaag tatttctttc cttttttcct catctacata
    33961 tggatgtcca ttgattacac gtgaaatagt agaaactgaa taacctgtga gctttgcgat
    34021 atctcgaatg tttgccactg ctgcttcgcc acctatacaa aaagattttc ttgtaaatag
    34081 tctaccacag ctggaccgca ttcaaaaaac tgatacattt ttccttcatg cgaaaaactg
    34141 atccgctgcc cgccccaata tatatctttt gtcaaatttt cgatttcatt cattggtatt
    34201 tcttttacta tattcctatt caacccttga aaactgtaca acgttaatac ggatcccttg
    34261 aactcgacaa acgcataaaa ataattgttc gttgtgccat ctgttatctc tacataagta
    34321 ttcattgcaa gccctccttt tgatactttg agtatagtgt atgaaacgcg tctcatagca
    34381 aggagtttgt tttgccaaag aaaagtttta ttcctctttc attattacca aagtctctta
    34441 ttttaaattg aatacattat aatgatactg taaat
//
LOCUS       DAFKHN010000026        34367 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFKHN010000026 DAFKHN010000000
VERSION     DAFKHN010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.026"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(59..187)
                     /locus_tag="LY912_001221"
     CDS             complement(59..187)
                     /locus_tag="LY912_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBM6954930.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="LY912_001222"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="LY912_001222"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBM6954931.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="LY912_001223"
     CDS             complement(1674..2729)
                     /locus_tag="LY912_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBM6954932.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="LY912_001224"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="LY912_001224"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBM6954933.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="LY912_001225"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="LY912_001225"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBM6954934.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="LY912_001226"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="LY912_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBM6954935.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="LY912_001227"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="LY912_001227"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBM6954936.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="LY912_001228"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="LY912_001228"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBM6954937.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="LY912_001229"
     CDS             10491..12050
                     /locus_tag="LY912_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBM6954938.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="LY912_001230"
     CDS             complement(12161..14092)
                     /locus_tag="LY912_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6954939.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="LY912_001231"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="LY912_001231"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBM6954940.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="LY912_001232"
     CDS             complement(15021..15773)
                     /locus_tag="LY912_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBM6954941.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAEIINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="LY912_001233"
     CDS             complement(15932..16141)
                     /locus_tag="LY912_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954942.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="LY912_001234"
     CDS             complement(16152..17480)
                     /locus_tag="LY912_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954943.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="LY912_001235"
     CDS             17616..17771
                     /locus_tag="LY912_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954944.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="LY912_001236"
     CDS             complement(17845..18432)
                     /locus_tag="LY912_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBM6954945.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="LY912_001237"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="LY912_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBM6954946.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="LY912_001238"
     CDS             complement(20012..21301)
                     /locus_tag="LY912_001238"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBM6954947.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="LY912_001239"
     CDS             complement(21455..22387)
                     /locus_tag="LY912_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954948.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="LY912_001240"
     CDS             complement(22544..23203)
                     /locus_tag="LY912_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBM6954949.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="LY912_001241"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="LY912_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBM6954950.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="LY912_001242"
     CDS             complement(24244..24534)
                     /locus_tag="LY912_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954951.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="LY912_001243"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="LY912_001243"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBM6954952.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="LY912_001244"
     CDS             complement(26821..28176)
                     /locus_tag="LY912_001244"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBM6954953.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICARYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="LY912_001245"
     CDS             complement(28200..29369)
                     /locus_tag="LY912_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954954.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="LY912_001246"
     CDS             complement(29366..30253)
                     /locus_tag="LY912_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBM6954955.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="LY912_001247"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="LY912_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBM6954956.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
BASE COUNT         9223 a         7481 c         6160 g        11503 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatgatt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtatcta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcga tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaagga
//
LOCUS       DAFKHN010000027        33903 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFKHN010000027 DAFKHN010000000
VERSION     DAFKHN010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.027"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            56..2221
                     /gene="acm"
                     /locus_tag="LY912_001248"
     CDS             56..2221
                     /gene="acm"
                     /locus_tag="LY912_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBM6954957.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2493..2978)
                     /locus_tag="LY912_001249"
     CDS             complement(2493..2978)
                     /locus_tag="LY912_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBM6954958.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3068..3413
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3458..4099
                     /locus_tag="LY912_001250"
     CDS             3458..4099
                     /locus_tag="LY912_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBM6954959.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            4118..4753
                     /locus_tag="LY912_001251"
     CDS             4118..4753
                     /locus_tag="LY912_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBM6954960.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4771..5586
                     /locus_tag="LY912_001252"
     CDS             4771..5586
                     /locus_tag="LY912_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBM6954961.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5905..7341
                     /locus_tag="LY912_001253"
     CDS             5905..7341
                     /locus_tag="LY912_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBM6954962.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7530..9977
                     /locus_tag="LY912_001254"
     CDS             7530..9977
                     /locus_tag="LY912_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBM6954963.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10207..11274
                     /gene="rlmN"
                     /locus_tag="LY912_001255"
     CDS             10207..11274
                     /gene="rlmN"
                     /locus_tag="LY912_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBM6954964.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11467..12570)
                     /locus_tag="LY912_001256"
     CDS             complement(11467..12570)
                     /locus_tag="LY912_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBM6954965.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13123..13671
                     /gene="aac(6')"
                     /locus_tag="LY912_001257"
     CDS             13123..13671
                     /gene="aac(6')"
                     /locus_tag="LY912_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBM6954966.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14217..15878
                     /locus_tag="LY912_001258"
     CDS             14217..15878
                     /locus_tag="LY912_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBM6954967.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(15948..16295)
                     /locus_tag="LY912_001259"
     CDS             complement(15948..16295)
                     /locus_tag="LY912_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBM6954968.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16379..17320
                     /locus_tag="LY912_001260"
     CDS             16379..17320
                     /locus_tag="LY912_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954969.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17321..18364
                     /locus_tag="LY912_001261"
     CDS             17321..18364
                     /locus_tag="LY912_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6954970.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18370..19440
                     /locus_tag="LY912_001262"
     CDS             18370..19440
                     /locus_tag="LY912_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6954971.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19430..20383
                     /locus_tag="LY912_001263"
     CDS             19430..20383
                     /locus_tag="LY912_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6954972.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20395..21405
                     /locus_tag="LY912_001264"
     CDS             20395..21405
                     /locus_tag="LY912_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6954973.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21690..22511)
                     /locus_tag="LY912_001265"
     CDS             complement(21690..22511)
                     /locus_tag="LY912_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBM6954974.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22608..22886)
                     /locus_tag="LY912_001266"
     CDS             complement(22608..22886)
                     /locus_tag="LY912_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954975.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23154..25163
                     /gene="metG"
                     /locus_tag="LY912_001267"
     CDS             23154..25163
                     /gene="metG"
                     /locus_tag="LY912_001267"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBM6954976.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25642..26229)
                     /locus_tag="LY912_001268"
     CDS             complement(25642..26229)
                     /locus_tag="LY912_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954977.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26404..27726
                     /locus_tag="LY912_001269"
     CDS             26404..27726
                     /locus_tag="LY912_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6954978.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            27881..28657
                     /locus_tag="LY912_001270"
     CDS             27881..28657
                     /locus_tag="LY912_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBM6954979.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28650..29219
                     /gene="rnmV"
                     /locus_tag="LY912_001271"
     CDS             28650..29219
                     /gene="rnmV"
                     /locus_tag="LY912_001271"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBM6954980.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29212..30096
                     /gene="rsmA"
                     /locus_tag="LY912_001272"
     CDS             29212..30096
                     /gene="rsmA"
                     /locus_tag="LY912_001272"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBM6954981.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30547..31176
                     /locus_tag="LY912_001273"
     CDS             30547..31176
                     /locus_tag="LY912_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954982.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(31300..32409)
                     /gene="ugpC"
                     /locus_tag="LY912_001274"
     CDS             complement(31300..32409)
                     /gene="ugpC"
                     /locus_tag="LY912_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBM6954983.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32618..33040
                     /gene="mgsA"
                     /locus_tag="LY912_001275"
     CDS             32618..33040
                     /gene="mgsA"
                     /locus_tag="LY912_001275"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBM6954984.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33363..33899
                     /locus_tag="LY912_001276"
     CDS             33363..33899
                     /locus_tag="LY912_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBM6954985.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
BASE COUNT        11271 a         5903 c         7023 g         9706 t
ORIGIN      
        1 ttgagagatg atatagtagg ttttattttt agttaaaata ggggagatag aaaaaatgaa
       61 aaagtgtaga aatattattt tatcaatgtt atttattatt actaatataa catcactgat
      121 tcctgttcat gtctatgcgg atgcaggcag agatatcagc agtaatgtca cttcgttgac
      181 cgtggaccca acgaatatta cagatggagg aaacataaaa gtaaaattct cgtttgacga
      241 aaaaaaacaa aatatccaac caggtgatta tctttggatc aattggccaa gtgaaggaaa
      301 tattcgcggt gaaggattcc aaaaagaaat cccattaatg attgaaaata aaaatgttgg
      361 aactttaacg gtcagaaaag attctgcgca ggttgtgttt aatgaaaata ttaaaaacct
      421 agactcagta gaaggttggg ggcaatttga gatacaggcc agaaacgtaa ccgataccgg
      481 tgaagaaaat acgggaccat tcaccgtgac gagcggtgat aaaacagcta ctgtaaatgt
      541 gacaaagcca gcttctggtt cttcttctag cgttttttat tataaaacag gagacatgct
      601 acctgaagat actaagcaca ttcgatggtt tttgaatatt aacaataacg gcacttatgt
      661 tgaacaacca gttaaaatca gtgatgaaat ccaaagtgga caaagattag atccaagtac
      721 gtttgaaatt aatcaaatac acttaggtga acagaaggtt tatagaggag aagagggaat
      781 ccaacaattt ttacaagatt tccccagcgc tacatttaat ttttcagtaa ctgataatta
      841 cattgaaata actataccaa aaaactttgt caatcttagg aaaataatgg tgagttataa
      901 gacgatcata gaaaacccag aacaaataaa ttttgagaat cattcggaag cttggtttaa
      961 agaatttaat aaacctgctg ttgatggaga aagtttcaat catacagtta aaaatatttc
     1021 agcttctggt ggagtcaacg gtacagttag aggcgaattg aagattttca aatatatcaa
     1081 tgacacagag attggtatcc caaatgtgac tttcgaatta agacgagcag atgaacagcc
     1141 tattcaagga cagtctagta tcctgttgac ttcgaatgaa cagggagaag ctagtatcaa
     1201 aggcctgcaa gtaggagact atgttgtaaa agaaaaagaa gcacccaatt ggattgattt
     1261 tgatccacta agttcaaatg aactcaaatt ctccataaac gaaaatgata cagagggagt
     1321 cagtttacct atttataaca agaaaaaggt tacgaacatc acagcaacta aaatttggaa
     1381 cggtggaacc actccaagac cgagtattta ttttaaatta ttcagagcaa gtacaaacaa
     1441 ttgggaacca gttcctgatg cagaaacaaa acgattagac aatggaataa cttcagtgac
     1501 ttgggaagat atccaacagt atgatgatag tggaaacgaa tatacgttta aagtgcaaga
     1561 agtagatcaa aacggaaatg attatgtccc ttcaggttat caaaaaattg aaaacgggct
     1621 agtcgttaca aatgagaata aagaagtcat ttcagtctca ggacaaaaaa catgggaaga
     1681 caatgagaac caagacggca aacgaccgac gacgatcaca gtaaatctat tagccgacgg
     1741 tcaaccgatc caacacaaag aagtaagtga aaaagatgat tggcgctatc gtttcacaaa
     1801 tctgccaaaa tacagagacg ggcaagaaat catctatact gtaacggaag acaacgtgcc
     1861 cgaatacagt acgacgattg acgggtataa catcaaaaac agttatacac cggaaaaaac
     1921 aaatatatct ataccaggta gccatataac accgtggaaa aattttccag agaagacaga
     1981 gagagagaaa attagaaatc tattctctca aaaattgcaa atatttgctc atacaggaga
     2041 atccagcgaa caaagaagca attatattag taagagagct gtacctaaac agataacaaa
     2101 taaatcaaaa agcattcttc ctaaaacaag tagtaaaaaa tctagttttg ctgtaatcat
     2161 tggtttattg atagtaacta tctgtgctgg gatattctta caaaaatata aaaaagttta
     2221 gttagaatat aatatttttt gttaaatatg actgaaatca aaagaataaa attccgattt
     2281 ataatcgaaa aaagaagcat ttttatatat gcttcttttt tcgtagaatc aataaatatg
     2341 gatttggcta actatggaag aatactcgta ttagttttca gcgttcatac tagttgttac
     2401 attgtttgat tggccaaaag aatttctgat atattttgtg ctaaataaag aaaaagacgc
     2461 ttgaattggg aaataagaaa actactctat cattacaaat tttcataaac tggcagatgt
     2521 tctaagtaaa caagtatctt ttcaaagtcg gaaaaatcca taatcaacgt agtggtattg
     2581 atatttggat gaaagcctac ggtatcttga cgatcaatag cagcatcgat cacgacttgg
     2641 atttttttct ctttgtcgtg catcaatgct aatggagtca ctgtacctgc tggaacgcct
     2701 aggaggtcag gaagctgttc ttcagaaaca aaagataagc gcttttcttt taattgttca
     2761 gctagttgtt ttaaatcggc gtgcttttca tcaggcaaga tgacaagata gatttgtttt
     2821 ccttttcttg atttcaataa tagatttttt acttgcggac caggtaggga aaaagggaca
     2881 tttttgactg acgtaatcgc aggatgatcg actttttgaa aagagatacc cagttttttt
     2941 agtagttcat aagcttcttg ttcggttgca cgactcatcg cgcatcaccc tccttttttt
     3001 attagtgtat cataaaaaag agttgacaaa tgaaaaataa tcatgtaaat tacacgtaaa
     3061 gttaaaacaa atgacatcga aaagaagagt agccgttagg tgtttttaga gagtctctgg
     3121 ttggtggaaa gaggcagcag ttaaccgtga aacacatctt ggagtcgatt ttctgaagcg
     3181 tatagtagga aaatccgggg agcccgttac agctgcggtc gttgctagat gaccagataa
     3241 ggctggcttt tccgtgagga gtcggtaaaa aaaggtggaa ccacgtgatt aacgtccttt
     3301 gatcttcgga tcaaaggact ttttgttttc atctgaacgg caacgactgt gtgaggtttt
     3361 ttctgcaagg aaaaaataaa cagaggtgga accacgtata atacgtcctc ttggcatttg
     3421 ccaagaggat ttttttattt taaaggagga aaagaagatg gagtatttga ttgaagttat
     3481 gccgcaatta ttagtaggag cactcacaac attgaaatta tttttattta ccttgattgg
     3541 ctcattacca ttagggattg ttttagcatt aggattgtct ttgcatttta agccgctacg
     3601 ctacttgctt caaacatatg tatgggttat gcggggaaca ccgctgttgt tgcaactgat
     3661 ttttattttt tatgggttgc cgacgattgg gatcgttttt gatcgtttcg aagcagcact
     3721 cattgccttt atcttaaact atgcagctta ttttgcagag atctttcgtg gagggataca
     3781 atcgattcct caaggtcaat atgaagcagc gcaagttttg caattaagtc cctttcaaac
     3841 ggtgacgaaa atcgtcatcc cacaagtgac aaagattgtt ttaccttctg tagggaatga
     3901 agttatcaac ttggtcaaag attcttcctt gatctatata ttaggtttag gtgacgtaat
     3961 gcgtgctggg aaaatcgcga tggaacgcga cgcgacttta ctgcctttgc taggcgtggc
     4021 aatcatctat cttacattga ctggtattct aacaatcata atgaaacaag ttgaaggaaa
     4081 attaaattat taccgctaac tgataggagg aagaaatatg attgaattga agaaagtgaa
     4141 caaagcattt ggtgaaaaaa aaataatcaa agatttgaat ctaatcattc cagatgggaa
     4201 aacattagct atcgtaggtc cttccggtgg cggtaaaacc acgcttttac gtatcttggc
     4261 tggcttagaa agttctgaca gcggagaatt ttatttagac ggtgtaccgt tcaacccatt
     4321 cgagcttaaa atgaaagaac aagttgtagg agtcgtattc caagacttcc agctatttcc
     4381 acatctgaat atttttgaaa acattacctt agcaccaaaa atggtattga aacagacaaa
     4441 agaagaatac accaaaaaag cagaagaatt agcggcttca ttagggatta gtgatttatt
     4501 gaatatctat ccttatcagc tttctggcgg acaaaaacag cgggtagcga ttgccagagc
     4561 attggctatg aatccacggg tattggctta tgatgaacca acaagtgctt tagatcctga
     4621 attacgccag caagtcgagc gtttgatcct atcattgaaa gaagatgggg taacccaaat
     4681 tattgtcacc catgatttag tatttgcaga aaatgtcggt gatcaattac taaaagtttc
     4741 cccaattcat taagaaagga gaagatagag atgaaaaaaa ccagttttct attcgctttg
     4801 atcgcaggtc ttcttctttt tgcaggctgt tcgaacaaaa aaacttcagc agataattgg
     4861 gcgactatca acgaagagaa aaaaatcgtt ataggtttag acgatacatt tgttcctatg
     4921 ggatttagag ataaagacgg gaagctcaca ggatttgata ttgatttagc caaagcagtc
     4981 tttgaacaat atgggattac ggtagacttt cagcccattg actggtcaat gaaggaattt
     5041 gaactgaaca atggaacgat cgatttgata tggaacggct attccaaaac gccggcaaga
     5101 gaaaagaaag tgcaatttac aaaaccttat atggaaaacg atcaagtgct gatcacacct
     5161 aaagaatcag gaatcacaaa ctttggacaa atgaataata agagattagg tgcgcaaaat
     5221 gggtcatctg gttatgatgt atttacgaaa caaccagaag tattaaaaga gatagtcaaa
     5281 aaccaagatg ctgttttgta tgatagtttt aatgaagcat tgatcgatct gaaaagcaga
     5341 cgggtcgatg gtctgctgat ggataaagta tacgcagact attatttgaa acaaagaaac
     5401 gaactagaag acttcaacat aacaaaaggt tcttatgaga gtgaggattt tgcagttggt
     5461 gcacgcaagt cagatagtac attagtgaaa aaaatcaatg aagccctaga tcaactagag
     5521 aaaacaggtg aattccaaaa aatatccgat aaatggtttg gcgaagatgt tacgccgaga
     5581 aattaacaaa taggggactg tgacaaaaga cgtgtcacag tccctttttc cgaataaaca
     5641 gtgttctcct gccaactcct tgtgactcgg agctgaatgg caggctcaca acctcttggt
     5701 aaacggtgtt caaaagccag tttttcggta ttaagccaaa tttatgcaaa aatgtagaaa
     5761 gccattttca caaaattttt cttactactc gaaactaagc gactttttca caacctcctt
     5821 tacataattt tattttgttg tggaaggggt ttcgtgttat tctaaaagag gaacgattga
     5881 aggttatagg aaaggaagag atgaatggaa cacaaagaac ttacctcatt tccaaaagat
     5941 tttctgtggg gctctgcttc tgcagcgtat caagtagaag gagcttggca agaagatggg
     6001 aaaggagaat cagtctggga tcgatttgta cggatacctg gaaagacatt taaaggaacg
     6061 aacggtgatt tggcagtaga ccactatcat cgttataaag aagatattgc tttaatgaaa
     6121 gaacaaggtc tgaaagctta ccgcttctct gtagcttgga cacggatttt tcctaatgga
     6181 cgaggagaag tcaatcaagc tgggctcgct ttttatgaga gattgatcga cgaattgatt
     6241 gaaaacgata ttgaacctat gttgacttta tatcattggg atcttccaca agcattgcaa
     6301 gatgaatata atggttggga atcacgtcag atcattgaag atttcactca ttatgcagaa
     6361 acattatttg aggcattccg cgggaaagtc cattactgga ttagtttgaa tgaacaaaat
     6421 atcttcactt cattaggtta tttgttagca gcacatccgc caggtgtgac agacccgaaa
     6481 cgaatgtatg aagttaacca tattgctaat ttagcaaatg catctgtcat caataaattt
     6541 cacgagttag aaatgcctgg aaaaatcgga ccaagctttg cgtatacgcc aaattatcca
     6601 attgacagta atcctgaaaa tgttctggct gctgaaaatg cagaagacct gatggccaat
     6661 tattggatgg atgtctatat gtggggaaaa tatccgattg ctgccatgag gttcttagaa
     6721 gaaaaaggat gggcaccaac gattgaagct ggcgatgcag aattgctaga atctgctaaa
     6781 ccagattttc ttgggatcaa ttactatcaa acggcgacga atgcattcaa tccattaaac
     6841 ggagttggtg ctggaaaaat gaatacgaca ggaaaaaaag gttcatcaga agaaactgga
     6901 gttcctggaa tgtataaaaa agttgagaat ccatttgtcg aacgaacaaa ttgggactgg
     6961 gagattgacc cagaaggatt aaggatcgga ctgcgtcgta tcacaagccg ttaccgcatg
     7021 ccggtactga ttacggaaaa tggcttagga gagtatgaca agttgacaga agataaacaa
     7081 atccatgacg actatcgaat caattactta caaagccacg tcaaagccat caaagaagca
     7141 atttcggatg gagcagaagt cctaggctat tgcacctggt cttatacaga tttgcttagc
     7201 tggctgaacg gttatcaaaa gcgatatgga tttgtatatg ttgatcaaga cgaaacacaa
     7261 gaaggatctt tggaacgata taagaaagac agttattact ggtaccaaaa actgattgaa
     7321 gaaaatggag agaaccttta gttcacatac ttaaaacaag aaggtacggc tggatatggc
     7381 cgtgcctttt cttgataaaa tcatttagaa attaagaaaa actgtaaaat aagctgaaaa
     7441 atgaaagaaa gcgtcagttc tttcaaacaa aactttagtt cccttacttt tttttgtata
     7501 atgaaacttg atgaaatgag ggataataaa tggcacaaaa gaaacggcct actaaaaaaa
     7561 ggaaaaagac gaaaaaaacg aaaaagcaaa aacagcagca ggaacaaatg ctgacgattg
     7621 gtgttgggtt tgccttgatt ttatttgctg tcttcggctt tttaaaatta ggttttttag
     7681 gaatattgat tgcaaacggc tttcggatca ttgcaggaaa tacttaccaa atcctctgtc
     7741 ttttattagc cgtattagga ttttggattg tcattaagaa tacagagttt tcaattggta
     7801 aaaaccgacg ctggtttggc ggcatactct tttatttcgg tatcttatta ttgttacatg
     7861 cccatttatt tggcaaactc catactgggg aaccaaatat catggggacg acatgggatt
     7921 tgttagccag tgatataaaa caaagtcaag tagacaataa cgttggtggt gggatgattg
     7981 gagcaatcct ttatcatttt acttacttct tgattgcaca gcctggaagt tatttagcag
     8041 cagtgctatt actggcagga ggagcattcc tgttcagtaa tctggaaggc tatcagctgt
     8101 taaatggtat ccaatcaatt ggagaacgag tacaggaatt attggaaggt gatcctgcca
     8161 agcaagctcg aaagcaagcg gcaaaggaag agagaatgaa acagcgcgca gaagcgaaag
     8221 aagcaaggcg cttagctgca aaagaagctg cagaaaaaga agctgcagaa tatgagaaga
     8281 aaaaagcggt gagccagcaa agggaaaata ctgctgatga atggcaggaa ccagaaaata
     8341 cagagccgga gcagctaagt tttgttccaa tcgacagttt tcaagaaaat atccatcctg
     8401 cgaatctaga gaaaccagta ccagatacac caaaacagac caatacagca gaaggttttt
     8461 cagatgagtt gccagaggat gacggtacct cattagaatt tgagattgaa gcagaacagg
     8521 aaaatcaaga ctatgaatta ccgacagttg atttgcttga ttctatacca actgtggatc
     8581 aaagtgatga gtataaaaaa attgaaaaaa atatcggcgt attagaacaa actttccaaa
     8641 gtttcggtgt cgatgccaag gtcgtcaaag ccagcttagg accatccgtc acaaaattcg
     8701 aagtccagcc ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca gatgatatcg
     8761 cgcttgcttt agcggcgaaa gatgtccgga tggaagcacc gattccaggt aaatcactga
     8821 ttggtattga agtaccaaat ggaaagatca gtatggtttc ctttagagaa atcatcgaag
     8881 cacaaccaaa ccacccagat aaattactag aagtaccttt aggacgtgat gtttctggac
     8941 gggtacaaac ggctgatctt tcgaagatgc ctcacttact cgtggctggt tcgactggta
     9001 gtgggaagtc agtagcaatt aatgggatta tcacaagtat attaatgcgt gctaagcccc
     9061 atgaagtaaa actgatgatg atcgatccga aaatggttga attgaatatg tacaacggca
     9121 tacctcatct gttgacgccg gtcgtgacga accctagaaa agcagcgcaa gccttacaaa
     9181 aagtagtaca agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga gtaagaaata
     9241 tttctggtta caatgaattt gttcaacaga aaaacttgga aaacggaacg aaacatccaa
     9301 ccttaccatt catcgtagtg atcgtagatg aattagctga tttgatgatg gtagccagca
     9361 atgaagttga agatgcgatt attcgtttag cgcaaatggc tcgggcagcg gggattcata
     9421 tgatcctagc tactcaacgt ccaagtgtgg atgttatcac aggaatcatc aaagcaaatg
     9481 taccttccag aatggcattt gcggtatcaa gcggtacaga ttctcggacg atcattgatt
     9541 ctaatggggc agaaaagctc ttagggcgag gagatatgct attcttgcca atgggtgaga
     9601 ataaaccgat ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa cgggtcgttc
     9661 aatttgttac agatcagcaa gaagctcatt atgaagagaa aatgatgccg acagatgaag
     9721 ttgaaacgac aggtgctcca gaacagccac aagatgagct gtttgaagaa gcaaaagcac
     9781 ttgtcgttga aatgcaaacg gcaagtattt cccttctcca aagaagattt cggatcggtt
     9841 acaaccgagc agcacgttta gtagatgaac tggaagctca tggagttgtt ggcccgtcag
     9901 aaggaagcaa gcctcggaaa gtattcattg agcaggaaga aacatcagaa acgttgccgg
     9961 acgataatga catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa ccaataaaaa
    10021 gacaaggcat gatgatacca aaagaaaaaa tggttttttt ccatcttttc taatacggta
    10081 tgatgtcttg tctttttagt ttttgtgaga ttaaagttct attcgattta tttgtgaagt
    10141 attgcattaa ggaaatgaat catgtatagt atgtagcgaa actttgagaa aaagagggaa
    10201 aatactttgg aaaaacagtc catttatggc ttgacgaatg aagaattaat caattggttt
    10261 atagaaaacg gcgagaaaaa attccgagct gcccaagttt gggaatggtt gtatcaaaaa
    10321 cgtgtaagta atttcacaga aatgacgaat ctatcgaaac aattgatcga aaaattatcg
    10381 gagcatttta tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc ggatggtaca
    10441 gtaaaatatt tgtttgaact ccctgataaa aacatgattg agactgtact gatgagacaa
    10501 gaatatggct tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg ctgtacgttt
    10561 tgtgcaagcg ggctgctcaa aaagaaccgt gatctgactg ctggagaaat tgttgcacag
    10621 atcatgatgg tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt ttcacatgtc
    10681 gttgtaatgg ggatcggtga gccatttgat aattacgaca atgtaatgga ctttttgcat
    10741 atcatcaatg atgccaaagg attggcaatt ggtgctcggc acattacagt ttccactagt
    10801 ggattagcac acaaaatcaa ggaattcgct aataacggct tgcaagtcaa tctggctatt
    10861 tccttgcacg cgccgaataa tgaggtgcga acatcgatca tgcggatcaa ccgaagtttc
    10921 ccaattgaga aattgatgga agctgtggat gagtatttag agaaaacaaa ccgtcgaatc
    10981 acgtttgaat atatcatgtt gaatcaagta aatgatagac cagagcatgc gcaacaatta
    11041 gcagatctat taaaagataa gaaaaaatta gcatatgtca acttgattcc atataatcca
    11101 gtcagtgaac atgatcaata ttctcgcagt ccaaaagctg atgtattgag attttatgat
    11161 gtattgaaga aaaacggcgt aaactgtgtg atacgtaaag aacatggtac agatattgat
    11221 gcagcttgcg gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa ataatcgtat
    11281 cctactcgtt ttttcaatta ccataaaagg agcagttttc ttaattaagg aactgttcaa
    11341 cttaaataag agaaaagatt ctatagcgaa agctataaag ctttttttga caagaaaaac
    11401 cctcatcaag caaagaaatg tcctcaattt gatgacagcc tgcttgatgg gggttttagc
    11461 aattatttaa ctgattttct tatatccttg ctggctttct tgtgtagcat gataagtttc
    11521 tacgtcaaga atggcctgtt taaatttttc tcgggtgatt tcataaggca catgtttaat
    11581 atcatttgtt gccatggctt tatctaagat tgcttctaaa tcggtcgtga cattgagatt
    11641 catgtcggtt aacgatactg gaagttggtt ctttttcata aacacataga ttttatcaaa
    11701 caaatcgaac tgctgatcca tcatcaataa ggtcagtaca ccataactga cagatgctcc
    11761 gtgaaggtat ccctccattt tttctagaac agtcgtaccg taatagaatg agtgtgccat
    11821 agcagaatta tagttattgt taactaaaac agaaaccaat ccggtagtaa caatgatatc
    11881 cgaaacgact tgttcaattg catatgaggg acgatcgtcg gcactatctt tcaatgcttg
    11941 cgtaccataa gtcaagagac gatcaatgca catttttccg atttggattc ctaatctatc
    12001 cgtgtagcct agatcatcgc cacgagcaga aaaagtagat tcgacttctt tggataaagc
    12061 atcgccaata cctgcccata agtatttatc aggtgcttcg gcaataattg ctgtatcaat
    12121 gaaggtgtgt acaggtggtt ttgaaggaaa gaagagtccg tccattacgc cttcttcgtt
    12181 atagatgaca cataccgcag tgacgggcga acagttcgaa ccaatagtgg gaaaggtgaa
    12241 gactggttta gctagttttt caccaatgac ttttacagta tcgcaagcac ggccaccacc
    12301 gactgcaaac aggacgtctg ctttttggac actttcatgc tggatcaact gttcaatatt
    12361 tccataagtt gaattacccc cgtaccagag actggcgaca acctctattt cctgtgtcaa
    12421 agctactttt attttgtttt ctgcctttga aagtgcagtc ttccctccaa tcagcactac
    12481 ttttgtccca tattctttga cgattccatt tgctttttca tacgcatctg ttccaatggt
    12541 ataatttggt aagaaaacac tttgactcat attcatttcc ttctttcttc gttgaaacgg
    12601 gttaaaattt taaagagtga tcgatctgac tgcggctgta gatggagtag aggtgaacct
    12661 aagacaggat aagtgatgaa taaggtggca tgaacacctt gaaatcatca ataagtatcc
    12721 taaaaacgaa caagtacaaa aacattgaaa acgacaataa tgaatttttg ttcctcttag
    12781 tatttctacc gattcccttt gcttttttgt aattatctaa aaattctaaa aattaagatt
    12841 attatatgaa aacaggtttt atttgtcaat tcataattgg ttttttttaa agcaaaagat
    12901 aatctatatc atgatgaaca aacagagttt tttcctccaa ttgatggctt tcctgatctt
    12961 tcctattttg aataaagtgt ttctgtataa tttttttatt ttataagtaa gataaataat
    13021 gaaagaatag agatactgat tggtagctaa agatttttga gcgagaacat ttcgtttttt
    13081 caaaaggact gttagaataa gcaagaacaa gggggaagac gtatgataat cagtgaattt
    13141 gaccgtaata atccagtatt gaaagatcag ctttctgatt tactgagact gacttggccg
    13201 gaagaatatg gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc agaacgaatc
    13261 gcggtagcag cggtagacca agatgagtta gtaggattta ttggtgcaat ccctcaatac
    13321 ggtatcacag gttgggaatt gcatccatta gttgtagaaa gctcccgacg aaagaaccaa
    13381 ataggtactc gattagtcaa ttacttagaa aaagaagtag cttccagagg aggaatcacg
    13441 atttatttag gtacggatga tttagaccat ggaacaacgt taagtcaaac ggacctgtat
    13501 gagcatacat ttgataaagt ggcttccatc cagaaccttc gtgaacatcc gtatgaattc
    13561 tatgaaaaat taggttataa aatcgtaggt gtcttaccaa atgcaaatgg ctgggacaaa
    13621 ccggatattt ggatggcaaa aacgattatt cctcgaccaa attctcaata ataaaaagag
    13681 gttgtgacag aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa ttacttcttg
    13741 aatttttgtg aaattccaac ttatttccga agaagctact tttggaacac cgtgtaccag
    13801 aggttgtgaa aaagtcgctt agtttcgagt agtaagaaaa attttgtgaa aatggctttc
    13861 tacatttttg cataaatttg gcttaatacc gagaaactgg cttttgaaca ccgtttattc
    13921 agataaggga ctgtgacaag acttttgtca cagtttcttt ttgtttattc ttttttatct
    13981 ttgtatggca ataatagaca atataacgaa aattatttaa tggcttttgg aagaccatgg
    14041 aaaaccttgt acaaagctat tttttctgaa aaattccttg aaacctcacg aaaaaatcat
    14101 tattttatga aaaagacaaa aaaaagtgtt gattttttaa taattattca ttaaactctt
    14161 aaacaacttc agaaaatatt aattattctg aaaattccaa taaaggggta cgtaaaatga
    14221 aaaagaaatt tacatttggt ttggttgcgg tatgcggcct tgtacttgct ggatgttatg
    14281 gcggcagttc agccacaagc agtagttcag caaaaagcgg ttcagcagat ggaggaggcg
    14341 tatttaactt agtcgtgcct caagaaatgc ctacagctga cttatcagtt gcaacagata
    14401 caatcagttt tacagcattg aataacgttt atgaaggaat ttaccgtctt gatgaagaca
    14461 gcaaaccaca gccggcagga gctagcgagt tggcagaagt cagtgaagac ggattaactt
    14521 acaaaatcaa attacgagaa gacgcaaaat ggtcaaatgg tgatcctgtt acagcagcgg
    14581 attacgttta tggctggcaa cgaacagtag acccagctac agcttctgaa tatgcttacc
    14641 tgtatgcgcc agttgaaaat gcagaagaca ttacagctgg aaagaaagat aaatcagaac
    14701 tagggatcaa agcagttggt gactatgaat tagaaatcaa attgacgaaa caaacaccat
    14761 atttccaata tctgcttgct ttcccatcat ttttcccaca aaaacaatcc gtagtggaag
    14821 aaaatgggga tgcctatgca tctgcaagtg ataaagctgt ttataatgga ccattcacat
    14881 tagaagattt tgatggacca ggaacagata cagaatggac ttataagaaa aatgatcatt
    14941 actgggacaa agatacagta aaactttctg aaatcaaagt cagtgtagta aaagaatctt
    15001 ctactgcatt gaacttattc aaagatggcc aagcagatga cgtgatcttg tctggtgagt
    15061 tagcacagca aaacgcaaac gatccagctt atacttctgt taaagaagcg cggacaagct
    15121 atatcgaatt caatcaacgt gaaaagaatt caccattcaa caatgtgaac ctaagaaaag
    15181 ctatttctta ttctatcgat cgtgaagctt tagtaaaaca agtactaggt gacggatcag
    15241 ttgtctctac aggattgatc ccatcagata tggtaaaaag tccaacaacg aacgaagact
    15301 ttgcaaaaga agctggaaaa ttagtttctt atgacaaaga taaagcaaaa gaatattggg
    15361 aaaaagcgaa aaaagaattg ggcgttgatt ctttagaatt tgatttgatg gcttctgatg
    15421 atgattcatc gaaaaaagta atcgaatatg ttcaaaactc aatccaagaa aacttggatg
    15481 gcgtaacagt caaaccaaca cctgttccat tctctgtacg tcttgaccgc tcaacttcgg
    15541 gtgattttga cgcagtacta ggcggatggg ctgctgacta tgcagaccca agcagcttta
    15601 ctgatttgtt tgtcacaggt aattcataca accgtggtcg ctggagcaat gcagaatatg
    15661 acgaagcagt taaagcagct tcatcaacag acgctggcga tgaacaagcc cgttgggatg
    15721 atttccaaaa agcaatcaag atcatctctg atgatatggg tgtcgttccg gtgtaccaaa
    15781 aagcagaagg tcacctagtg aatgaaaaaa tcaaaggtat cgttcaccat gcggcaggcg
    15841 cttcatggga ttacaaatgg acatacgttg aagaataatc gttaataccg tgagcatgag
    15901 aaaaaacgag gctgcggcaa atgtcgcaac ctcgttctca tattcactta tcctaacaaa
    15961 gaaaaaagca tgaaaatagc agaaagagca attagtattc cggcaatgat cagccaaaag
    16021 ctgtacatac cgtagctggc agacgagagc gaggaaaatt ctggtttttt ctttcggttc
    16081 cttgttcgtg caagatggac cgatcgctga aaatgatcga agaaacccga agaaaagacc
    16141 cataaaaaac cgccgataat cagaaacggc aatgaccata agaatagatc attagataat
    16201 tgaatgagtg taaaggaatg gttgatgaga ttttttatta aaataaccag aatcagtaga
    16261 aaagctactg cgtaggggat agattttttt ttcatttgat tgctccttta tttttggttc
    16321 attatctaat aatgtagcga aacatctgtc agaagtcaaa agctaggggg aaacaatagt
    16381 gaatagttat atcaaatatg tattaaaacg tgtctttttc atgatcatca cgctttggtt
    16441 aattgcaaca atcacctttt tcttgatgca attgctgccg ggcacgccat atacgaatca
    16501 ggaacgtttg agtcctgaaa caatcgagat gctaaataaa caagtcggtt tggataaacc
    16561 agttatcgta caatatggga tttatctttc taatttgctt caaggagatt ttggaatttc
    16621 cttccaattt aaaaaccagc cagtcgcaca tttgttagct ggaagaatcg gaccatcctt
    16681 gcagttaggg ttacaggcaa ttatctttgg aacagtccta gggacgattt taggaacgat
    16741 ctctgccatg aagcaaaata catgggcaga tacatcttct acactcgtag cgatattagg
    16801 tcgttccatt ccaaactttg tatttgctgt tttattacaa tatatctttg caatcaaatt
    16861 acaagttttg ccaatcgcaa aatgggatgg ctttgtgtac acaatcttac caacaattgc
    16921 gttggccatg tcgccgcttg ctgactctgc tcggtttatc cgtacggaaa tggtggaagt
    16981 actgcatagt gattatgtgg aattagcaaa agcaaaagga ttgagccgtt gggaaatcgc
    17041 ctttaaacat ggtcttcgaa atagtttgat tccattgatg actttattag gaccgttagc
    17101 tgtagcattg atgaccggat cactggtggt agaaaatatc tttgctattc ctggtatcgg
    17161 ggaacaattc gttaagtcaa tcacaacaaa tgattatcct acgatcatgg ctgtaacgat
    17221 cctttactca tttatgctga tttttgttat tttgatcgtg gatctattgt acggtctagt
    17281 tgatccaaga attcgtgttt cagaagggag ccgaggataa atggaaatga taccaaagcg
    17341 ttatgaaaca gttgcagata tccctgcgga tgaatttctt ccattacaaa aaaataccga
    17401 agaagaacgt gaacagatta ctgcaccttc tttgaatttt atccaagatt catggcgccg
    17461 tttaaagaaa aacaaagctg ccgttatttc aatggtttta ctattggtca tcattttgat
    17521 ctctgtgatc acaatctttg tttctcctca tgatccaact gcccaaaacg tggcttatat
    17581 caatttgcct cctcgtattc cgggaatcaa tatcgatgga ttgaatggaa aagcaatggt
    17641 tggtggtgaa cttgttgata aatatgctca agcaaacgtc ccttcaaacg taaatttctt
    17701 tttaggaaca gacggtttgg gacgtgatgt attaagccgc ttatttatgg gaatgagaat
    17761 ctcgttgctg atcgcattta ttgctgcatt actagatgta acgattggtg tagcttacgg
    17821 gttggtttct ggtttgttag gcggacgtgt cgataacgtg atgcaacgtt ttttggaaat
    17881 cttatcagga attccaaacc tcgttgtcat gattttgatg ttggtcgttt ttgaaccagg
    17941 aattttttca atcgtggctg ctatggccat cacaaactgg ataccaatgg cacgtatcgt
    18001 tcgtgcacaa acaatgaaat taaaagatca agaatatgtt ttagctggat tgacattagg
    18061 tgaatcaaga atgaaaattg cattcaaaca tattttgccg aatatctcta gtgtcattat
    18121 tattcaaatg atgtttagta ttccatctgc tattttcttc gaagcctttt taagctttat
    18181 cggtttaggt cttacgcctc cgtcagcttc attaggaacg atgttgagcg aagggtacaa
    18241 gacattcctg tatctgcctt atctattatg gattccggca gtaactttat cggttatcat
    18301 gattggcttt aacttacttg ctgatggatt gcgtgatgcc tttgatccta aaatgaaaga
    18361 gtgaagacga tgacgaaaat tttagaagtg aaagacttag aaatctcttt tgatacgtat
    18421 gctggaaagg tacgagcgat tcgcggtgtc aattttcatt tgaataaagg agaaacattg
    18481 gcgatcgttg gggaatctgg aagtggaaaa tcagtgacga ccagaagcat catgcgcttg
    18541 ctgtcaagca acgccaatat agatgctggt caaatcctct ttaaaggtaa cgatatcgtt
    18601 ggaaaatcag aaagagagat gcaaaaaatc cgtggtaaag aaatagcgat gattttccaa
    18661 gatccaatga cctctttaga tccgacgatg cccattggga agcaagtcgc tgagtccctt
    18721 agaaagcata ataaagtttc aaaaaaagag ggacaaaaag ctgcattaga attgcttaaa
    18781 ttagttggaa tacccgaagc tgagaaacgt atcaacagtt atccgcatca gttctcagga
    18841 ggtcagcgtc aacggatcgt gatcgcgatt gcactggtat gttatccgga aatcctgatt
    18901 gctgatgaac ctacaacagc gcttgatgtg actattcaag cacagatttt ggagctgctg
    18961 aaagaaattc agacaaaaat cgatacatca attatcttta tcactcatga ccttggtgta
    19021 gtagcgaatg tcgctgatcg tgtcgctgtc atgtatggag gaagaatcgt tgaagttgga
    19081 acatcggaag aaattttcta caacccgcaa catccctata cttggggact gcttggttca
    19141 atgccgacat tagatagtgc gaacgatcga ttgtatgcta ttcctggttc tccaccggat
    19201 ttattgaacc cgccaaaagg agacgcattc tatccaagaa atgaattcgc gatgaaaatc
    19261 gatgcagaac aagaaccacc attttttgaa ctatcaaaaa cacacaaggc agcaacttgg
    19321 ctacttgctc cgcaggcacc caaagtgaca ccgccagaag aaatccaacg tcgctgggct
    19381 atctttaaag agaaacaaaa acatacttac ggtcaaggag gaattgctga tgccaaataa
    19441 actacttgaa gttaaaggat tgaaacagta tttcaatgta ggaaaaaaga atgaagtaca
    19501 tgctgtaaat gacatcagct ttcacattta tgaaggagaa acattcggtt tagttggaga
    19561 atctggaagc ggaaaatcca ctactggccg tacgatcatt cgcttgaatg aacctactga
    19621 tggtgagata ttattcgacg gtcaagatat aacgaagatc aaagataaaa aaggtttgac
    19681 gaaattccgg catgatgttc agatgatctt tcaagatcca tacgcttcgt tgaatcctcg
    19741 tatgaaagtc agagatatca ttgccgaagg aattgatgtt aatggactag ctaaatcatc
    19801 tgaagagcgt gcaaaaaaag tcgatgatct attgagaact gttggattga atccaagcca
    19861 cggtactcgt tatcctcatg aattttcagg tgggcaacgc cagcgtattg gtattgcacg
    19921 agcattggca gtaaaaccgc gttttatcat ttgtgatgaa ccaatttctg cactagatgt
    19981 gtcgatccaa gcccaagtgg tcaatttgtt gcaagatctc caaaaagaac atcaattgac
    20041 ctatctattt attgcacatg atttgtcgat ggttaaacat attagtgacc gaatcggtgt
    20101 aatgcataac ggcttgttat tagagatggg aacaagtgat gaaatctata atcacggtgt
    20161 tcatccttat acagaaagtt tgttatctgc tattcctcta ccagatccag accatgagag
    20221 aaaacgcaga agaatcaaat atcaacctga accagatgac ggacaagtac gtcaacttcg
    20281 tgaaatcgca ccagaacatt ttgtctatgc aactgagcag gaagtcccat attacgcaaa
    20341 aaaactaaaa cgacaaaagg aatctcttct ggttgctaac taggagggac atagatgcta
    20401 aaagctttta aattccgtat gtatccgaca gaagaacaaa aacagcaatt gattcgtact
    20461 tttggatgtg ctcgatttac ctataaccat ttgctgaaaa agcggcagaa aagttggcaa
    20521 caaacaggag tagccaattt ttcgctcaca cccgctacat taaaaaaaga atacccattc
    20581 ttaaaagaag tagacagtct tgctttagca aatgcacagc ttaatttgga tcgggctttt
    20641 cgcaattatt tcaagggacg tgccagcttc ccaaagctta aaacgaaaaa aagtatgtgg
    20701 caatcttata cgaccaacaa ccaaacccgt acgatctatc tggaaaatgg ctacttaaag
    20761 ttaccaaaac aaaaagaact aatcaagata aatcagcatc ggccagttga aggatcgatt
    20821 cgctccgcta cgatttctgc tcgatataat gaagaatttt atgtcgcact actttgtgat
    20881 gtttcgccag taaaaaaaga atctttagct aaatggatcg ggatcgccta tcatccgaag
    20941 acattgatcc aaacatctcg acctctagaa gtaactttac caaaatttca ccagacagaa
    21001 gaaaagctgc aacatgcaca gcggaaattg aatgtgaaag tccgctccgc tcaccataga
    21061 aagatcaggt tagatcaggc aagcaattat cagaaacaaa agagaaaagt aatggatctt
    21121 tatctgaaac aaaagaacca gcgagaagat tatcttgaac aattatctgg gaaattggtc
    21181 aaacaatatg actacttatt tgtagaatct tttccaaaag aagaggcaca tgctgatttt
    21241 tctattcacg actggcataa attaataaca aaattgcgtt ataagtccca atggtataat
    21301 aaaaaatttc ttttgatcaa taccgacgga gcagaagaaa gcaattccgt aagaaagagc
    21361 caagtagtag aaaaaatggg cagacattcg gttatcaagg gataaaaaat gaatgaaact
    21421 gataggagcg ttagggttag ccttgttaat aaaaagtctt aatgactttt gtttctagga
    21481 atttttcttt tgaagaaaag ctcactaatt atgacaaacc aataaaacaa tagcagaaaa
    21541 agttcgtacg agctttttct gctattgtta attttttatt cagaaagttt acgaatacat
    21601 caaaattctg aaacaaaaaa cgtaactcac aaagagttgt ttttgcgttt tttcttgaat
    21661 gattaggtct gaatcttttg ctcacaacct tattcatggt gccccggctt gagctgatag
    21721 atttttgaag gacggccgat tcctacagga cgttcaccga tctcatcgaa atattggagc
    21781 atagctttct taaaattgga atgatcgatc gttttataat cgatccctaa gaatttagca
    21841 aatacttttc gagcttccgt aatcgtgaaa tctttaccta aaacttgtag aacttgcggc
    21901 tcgtgttcca ttttattgac tacacggttg aatgctttca agatgatttg actatggtca
    21961 aaagccaaag tatctttgcc agaagactct ccagtgacta aatcaagcga gatagccact
    22021 tctccgctag ataaatggat cttgttacta tgacgttcta gtgtgaacca gcgtacttcc
    22081 ttggcatcat ctccggcgat tagcggttct tctccaataa aggctaagta gctgactgtg
    22141 acgacccagc ctcgcggatc tcgattaggc gtactgaatg tatgcagttg ctcaatattt
    22201 tcttttgaaa taaccacacc agtttcttcc tttgtttctc ttaagacgct ttctccagtt
    22261 gactcatcct tttggacaaa gccaccaggc aatgcccatg aatttcgata aggatgccct
    22321 tttctttgga tcaacaaaac tttcagctga tcttcttctt tgttatagca catcagtacg
    22381 atatcgacag tcaaagaggg cttgtcatat tctggacgtt cctgtttttg ataccagtta
    22441 agaaattctt cttcacttgc tttatgttca taatataatt tttcttcttc tttagaagca
    22501 aaacggttca tctgaccacc tccattgaca gtaaaagtac tttttacctt attgtagcag
    22561 actctgaaaa aaaaccaagg atttacttga aaaatctagg ttatcattta aatatgaaaa
    22621 ataaatggaa gtatgagatt gaataaaaag aaaagcagat aaaacggcaa tactttatac
    22681 cgctcttcac gaatggcaaa gaagccacaa ataacgatat atacgtcaat gataaaacgc
    22741 aaaatccaag ctgctgtcat aaaactgttc aaatgcccat ggaggttaaa ataaccatac
    22801 atacgaatat aaaaatagct gaatattaaa tgtgctaatg aaagaaaagc aatactaagt
    22861 gtaaaaaaaa gatgtttctt ctgcatgatt gttccagtcc cttactaaga tagatagtct
    22921 ttattatacc acgtgtgagg ggagaaataa aaagccgttt tttagtagat atgaaacaaa
    22981 acaaaaaccc gcatttattc aacctattca tccttttaaa ggatagattg aacgtagata
    23041 gaagtcgttt atccagtctt tttcattttg aaaaaaagct aacagcatgc tttttttatg
    23101 gtatactagc aaggaaacga attcgcatca tgcgataaag gaggaagagc cccgtggcag
    23161 aaaaggaaac tttttatatc actacgccaa tctattatcc aagcggcaaa cttcatatcg
    23221 gcaactcgta tactacgatt gcatgtgacg caattgctcg ttataaacgg ttgatgggct
    23281 ttgatgtgtt ttatctcact ggagtggatg aacatggtca aaaaatcgaa acaaaagcag
    23341 aagaactagg tgtaaaaccg caagaatatg tagataaaat ggcggctgat gtcaagaaat
    23401 tatggaaaac gcttgatatc agttatgata aattcattcg cacgacagat gattaccata
    23461 aagcagctgt tcaaaaaata tttgatcgtt tattagaaca gggagatatt tacttaggtg
    23521 aatatgaagg ctggtactct gtttctgacg aagaattctt tacagaaaca caacttgcag
    23581 aagtgtacaa agatgacgaa ggtaacgtga tcggtggtaa agcgccaagt ggacacgaag
    23641 tagaattggt aaaagaagaa tcatacttct tccgcatgag caaatacgca gaccgtctat
    23701 tggaatacta tgaagaacat cccgaattca tccagccaga atctcgtaaa aacgaaatga
    23761 tcaacaactt tatcaaacca ggattagagg atcttgcagt ttcacgaaca acttttactt
    23821 ggggagtacc agtcaagagt gatccgaaac atgtggtgta tgtatggatc gatgcattat
    23881 ccaattatat tactgcacta ggatatggct ccgaagatga aagtctattc gaaaaatact
    23941 ggcctgcaga tgttcagatg gtcggtaaag aaatcgttcg ctttcatacg atctattggc
    24001 caatcatgct gatggccctt gatttgcctc tacctaaaaa agtatttggg catggctggc
    24061 tattgatgaa agacggaaaa atgtctaaat caaaaggaaa tgtcgtttat cctgaaatgc
    24121 ttgtggaacg ttatggttta gatgcactcc gttattattt gcttcgtgct gttccgtttg
    24181 ggtcagatgg tgtctttacg ccagaagatt ttgtttcccg tgtcaattat gatctggcaa
    24241 atgatctagg gaacttattg aatcgaacga ttgctatgat caacaaatat tgtgatggac
    24301 tcgttcctga ctatgcctca cttgtcactc catttgatag tgaactgtct acgacggctg
    24361 ctaacgttgt cggacgttac catgatgcaa tggaaaaaat ggaattcaat acagcattgg
    24421 ctgaaatctg ggtgctgatt tctcgtgcaa acaaatacat tgatgaaaca gaaccatggg
    24481 tattagcaaa agacgaagaa aagaaagctg aattgaatag tgtcatgatc catttagctg
    24541 aatctttgcg tatcgcagcg atattacttc agccaatcat gacagaaacg ccagagaaga
    24601 tcttcaatca actaggattg gactctgaaa caatgaatct tgaaggatta cactttggcg
    24661 aatttccttc aggaacaaaa gtagttgcaa aaggtacacc aatcttccca cgtttagata
    24721 tggaagaaga agttgctttt attcaagaaa aaatgtctga aggtactcaa acaaacgaag
    24781 atacagtcaa atgggatcca gaagaaacag aacttgtttc aacgaaagaa aaacaaatca
    24841 aatttgatgt atttgaaaaa gtagaactaa aagtagcaga agtcatcaac tgtcaaaaag
    24901 tagaaggggc agataagttg ctgcaattcc gactagatgc tggagacagc caagaccgtc
    24961 aaatcttgtc aggaatcgct gaattttatc ctgatccaag cgaattgatc gggaaaaaag
    25021 tcgtcattgt agcaaatctg aaaccacgaa agatgcgtgg acaaatcagt caaggaatga
    25081 tcctttctgc agaagcacca gatggctctt tacaagtaat cgaagcacca aaatccatgc
    25141 caaatggctc agaaatcgca tagaaattca aagggggtat gacactagtt gtgtcatacc
    25201 ccctttttcc gaaatttgag aagcaatttt cgtaaattcc ttcttattac ttgaagccaa
    25261 tcatataata cagaaacaga gaactatcca aaataaatcc tagaaaaaga agtacgagct
    25321 tcgctgattt ttgttaattt agaataatac taataggaat cgtaaaaaca gaaaaaaagc
    25381 ataatgataa agggtcgggc agattttaat tgattcatct ggtactcttt tttattgtcc
    25441 ttacattcat aaagtttgaa tgcaatgact ttattacatc tatatttata tctaacagta
    25501 gcgttgatgt gttaattata agttctatca ctttatgttc aattagtttg tgctcttata
    25561 tgtgtgattg aaaatataga taaaaaaaca atcatcggct ttgacttcga tgattgtttt
    25621 ctttattttg taaaaatcct atcacttgat tttatggtaa ccttttattt ttgtcttcaa
    25681 acggcttggt aagagagcag taagcagtgc aaatgggatc gaaaagacat accagaaaat
    25741 cgtacgtccg ataccataat gttgatagag ctttgtcaac atcacgtgta acaagatcaa
    25801 ccctaaaagc aaggagccag ctataaacca atgattatcc caatgcatga cttcactaag
    25861 tgccatcact ccaaaaggat agaaataaaa atagatcccg actaaggtca tccgccagtt
    25921 ctttgtaaat gttccgatat tcaataaaaa gaaaatcgct gaaagcaaaa taccgatagg
    25981 cggaaaaagc ccaaccaaaa aggaatacaa catcccccac aagatcatca caggaccttt
    26041 gatcaatgca acgattgcga tgaacaaagt cagcaatatt agtttttgtg ataacgttgc
    26101 aacagtcatt aatccaaata aaattaatgt gaaccaatgc caatgggact gctgttgttc
    26161 tttacgggaa aaatcgaccc ggttggataa ataatctgct aatttcggat aagaacgctt
    26221 aaaatccata aactgttcct ccttcgtgga aaaggtaggt ttagtatacg aaaaataaaa
    26281 aagaaataca tccgtcttaa gagggagttt ttcactgaaa gtggagaaaa aagaatggta
    26341 aattaaaata ttctcagtta tactgaaaat tataccaaat ttcaaagaag aaagaggatg
    26401 ggaatgaaag gcaaactaaa acgagaaatc aatctgtttg gcgcattagc taccgttatg
    26461 ggaaccgtga tcggtgcagg cgtcttcttc aaaactgctg ctgttactgc tagtactcag
    26521 tctacaagtt tgacattgct agcttggctt ttgggtggtt tcttaacgat ctgtgctgga
    26581 ttgacagtgg ctgaattagc tacagcaatc ccggaaactg gtggagctgt aaaatatatt
    26641 gaagctgcgt atggaaaatt gcccagcttt ttattaggat gggcgcaaag cttgatttac
    26701 tttcctgcta atattgctgc attatcgatt atctttgcga cacaattgac gaacttatta
    26761 caattatcta ccgattatct tttgttgatt gcagtgatca ccgctgtttc tgtgacaggg
    26821 ttgaatttgt tagggacaaa agtcggtgct tctgtacaat cagtgacgtt gattgttaaa
    26881 ttaataccaa ttgctgtgat tgtcatatgg ggattattga ccccaggaca aggaactgtc
    26941 cagttatttc caatcgaagc tggaaaagat gttacttttg tcgaaggatt gagcagtgcg
    27001 ttgttagcaa cgttgtttgc ttatgacggc tggttaggtg tcggtgcaat ggcaggggaa
    27061 atgaaacggc cggaaaaaga tttgcctaaa gcaattattc ttggtttgag ttttgtaaca
    27121 gtcgtttatc tattgatcaa ttttgttttt ttgaaaactt tgccgattga tcatcttgcc
    27181 ggtaatttga atgcagcttc tgaagcatca gacgtcattt ttggaggaat cggtggaaag
    27241 ctggtcacta ttgggatctt gatctcggta tacggtgcat tgaacggtta tacactaact
    27301 gggatccgcg tgccttatgc gatggcttta gaagacgagc tacctttcag taaacagctg
    27361 acaaagcttt caaagaagtt tacggttcct tatgttcctg cggttttcca gttagcagta
    27421 gcttgtatta tgatgagcct tggttctttc gactttttaa cagacatgtt gatttttgtg
    27481 atgtggctat tcagtttact gatttttatc ggtgtcttta ttttaagaaa aaaagcgccg
    27541 gaattgccac gtccatataa agtaccactt tatccaatcg ttccgattat tgcgattctc
    27601 ggtgctattt tcattttagg tatgacgatg atgacgcaaa cgaaattagc attgatcggt
    27661 ataggtgtta ccttgatagg tatcccagtc tattatcaaa aaaagaaaaa acgctcagaa
    27721 gagtaaaata tttcaacaac agacagaaaa agtacgaact aggtcctcta gatcttcgtg
    27781 ctttttctat ttcaataaaa caagttcttc tattttgatt tttgctactt ctgcaagtag
    27841 tgcttatgtg ctaaagtaag aatgaaaagg agagataaac atgatatttg attctcatac
    27901 ccatttaaat gctgaacagt tcaatgaaga tattccagaa acgattcagc gagcacaaga
    27961 aatgggggta acgaaaatgg cggtcgtggg cttcgatacg ccaacgattg aaaagtcttt
    28021 gcaattaagc catgactatc caaatatata cagtattatc ggctggcatc cgacagaggc
    28081 tggcagttat acgaaagaaa tcgaaaataa attacaagaa caattgactt taccaaaggt
    28141 tgtagcatta ggggaaattg gcttggatta tcattggatg gaagacccga aagaagtcca
    28201 agataaagta tttcgcagac agattgctat cgcaaaagaa atgaacctac caatcagtat
    28261 tcatactaga gaagcacttg aagacacgta tcaaatccta aaagaagaag atgttcgaga
    28321 tatcggtgga atcatgcata gtttcagtgg tgattatgaa tgggcaaaac gatttcttga
    28381 cttagggatg catatttcat ttagcggtgt cgtcactttc aaaaaagcat tagacgtcca
    28441 agaggctgca gcaaatgtac caatcgaacg attacttgtg gaaacagatg ccccttatct
    28501 ggcaccagtt ccttttagag gaaagcgaaa tgaaccaggc tatactcgtt atacagtaga
    28561 aaagattgct gaacttcgga atcttccgac agaagaagtg gctgcccaaa catggacaaa
    28621 tgcgcaccga ttatttggtc taagcgaaca tggataagat gaagatccaa gagattatag
    28681 tcgttgaagg aaaagacgat acaagaaggc tgcgggaagt agttgatgca gatacgatag
    28741 aaacaatagg gtctgcaatc aatgaagaga tcctgatgca aattgaacat gcccaagaga
    28801 ctcgtggagt gatcgttttt accgatcctg atttttcagg agaaaaaata agaaaaatca
    28861 ttatggaagc tgttcctcag gcaaaacatg cttttttgcc gcgcacacaa gctaaaccaa
    28921 agaaaaaggg aagccttggt gtcgagcatg caagtgatgc tgctatttta gaagcattga
    28981 aaaaggtcgt gacgccagac atttcccaaa cggctgtttc tgaaatcact agacaagacc
    29041 ttttagacta tggtttaata gctggggcac aagcaaaaga aaaacgagaa aaactaggtg
    29101 acgagttgcg catcggttac acgaacggca aacaattgga aaaacgtttg aagatgtttc
    29161 gtattacgcc gaaagaactc gcccaagcaa tgaaaatagt ggaggaacaa catgagtgaa
    29221 tatcgtgaaa ttgcgacacc ctctagaaca aaagagattt tattgaaaca tggtttttca
    29281 tttaaaaaaa gtttaggaca aaattttctg actgaaccaa atattttaag gaaaatcgta
    29341 gaaactgcgc aaatagatga acatacgaac gtgatcgaag ttggaccagg aatcggtgca
    29401 ttgacggaac aattagccaa gcatgcaaaa caagtcgtag catttgagat cgatgatcgt
    29461 ttgatccctg tattggctga tacgatgcaa ccctatgaca atgtgactat tgtacatcaa
    29521 gatattttaa agaccgattt gtcaacagct gttagagaaa catttcatga ggagcttccg
    29581 ttaaaagtcg tagcgaattt accttactat attacgacac cgatcatgat gcattttctt
    29641 gaatcagatt tggttgtgga tgaactagtc gtcatgatgc aaaaagaagt agctgatcgt
    29701 atctctgctg aaccaggaac gaaagcttat ggttcattat cgattgctgt tcaatattat
    29761 atggaagcca gtttagcatt catcgtacca aaaacagtat ttgtccctca gccaaatgta
    29821 gattcagcga ttttgaaact gacaagaaga gatataccgg cagtcgaagt gacagacgaa
    29881 aaagcatttt tccgattgac aaaagcggca tttcagcaaa gaagaaaaac gctttggaat
    29941 aacttgcagc attcgtatgg caaagatgac cagacaaaag catggttagc aaaaagcttg
    30001 gaaacagctg gaatcgatcc aaaacgtcgt ggggagactt tgtcattaca agaattcgcc
    30061 gcattaagca atgcgatgtc agaaaatatg cagtaaaaaa agaggttgtg acagaagttg
    30121 tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt tcctcatgtt
    30181 tttcgtttgt ttgggcttat taccgcagat gcaagctttt gaacaccgtt taagaaagag
    30241 gttgtgggcc tgccgtttaa ctctaagtca caaggaacaa tttcaaaaaa cagcttctca
    30301 tgtttttgag ttagttggtc ttattacttg atgcaagctt ttgaccacta ttatgccgaa
    30361 caaggagatg tgacacaaat tttgtcacat ctcctatttt tgtttcttga tcaaaaaatt
    30421 cttatacttg atactcacac tcattttgta tggatttaga aaagaatatg tgtcttgaca
    30481 gttattagta agtgagttat actaagtcga catttatgtg tcaagacata ttaggagaga
    30541 gaaaaaatga gaaaaaattc agttcgaaaa ctaacgattt ctgctttatt gattgggatg
    30601 ggggtcatta tcccaatggt catgcctaaa atcatgattc caccagcttc ctttactttg
    30661 gcgtctcatg tgccattatt tattgcgatg ttttttacac caggagttgc agtggctgtt
    30721 gcgctaggta cgacatttgg tttcttttta acaacgccgg ttatcatcgc attgcgagca
    30781 ttgtcacatc ttgtgtttgc gttgattggg gcttggtact tgcaaaagca tccgagtatc
    30841 gttttaaaaa atggacagtt tacttttgct aattggcgtt tccaagggtt caattttgtg
    30901 atcggtgtga ttcattcttt agcagaaatg ctagtagtca gcatctttta ctttattggt
    30961 aatatgcctg aaacatatta ttctcaagga tatttttata cagtattcat cttgatgggg
    31021 attggtgggc ttatccacag tttagttgat tataatattg cttattttat agcaggaaca
    31081 ctcagcaaat attttgatat ccccgtattt acggcagcaa aaaaagaaaa tcggaaagag
    31141 tcgattcaag ggtacgcgaa gaaaacgaca tattagacat gatctctcaa aaaaaaaact
    31201 ctcatctagt aatggataat aaatcctcta agatgagagt tttttgtcct aaaaagagct
    31261 gcaccaacat cttctggcac agctctaaca gggggcaatt tatggaagtt tgatgacttg
    31321 ttctgtttct ttatcaaaga agtggccttt gctgatgttg aaggcaaggt cgactatttc
    31381 gcctggttta tggaaatctc ttgcatctac ttttgagatg aactcagtag aaccagtttt
    31441 tgtgtaaagc atcgtttcag ctccaagtaa ttcggaaacg acaacttctg atttcactac
    31501 ggcttcaggt gaagcttcaa gggctacttg ttcactgtgg atgtcttctg gacgaatacc
    31561 gaagataact tcttttcctt cataaccttt ttcaactaat actttgtttt ttccttcagg
    31621 aatacgaagc ttaagcccat gtccatctgt gataacacca tttttcaatg tcacattaaa
    31681 gaagttcatg gcaggagatc caataaagcc ggcaacgaac atattgacgg gtgtatcata
    31741 aacttctttc ggtgtaccga tttgttggat aaatccgtct ttcatgataa cgattcggtc
    31801 agccatagtc attgcttctg tctgatcgtg agtaacatag atggtcgttg tttcaagacg
    31861 ctggtgaagt ttggcaatct cagcacgcat ggctacacgt aatttagcat ctaaatttga
    31921 taatggctca tccattaaga agacttttgc atcccgaacg attgcccgtc ccaatgccac
    31981 acgttggcgt tgtccaccag ataaagcagc tggttttcgt ttcaagtatt ctgtcagacc
    32041 taagatctct gctgcattgt ccacacgttt tttgatgtct gctttatcat atttacgtaa
    32101 tttcaagcca aaagccatat tatcaaaaac agtcatatga ggatacaatg cgtagttttg
    32161 gaaaaccatg gcaatatcac ggtctttagg tgccacgtca ttcatgactt ttccgccgat
    32221 atttagttct ccttcagaga tatcttccag tcccgcgatc attcgcaaag tagttgactt
    32281 tccacaaccg gaaggaccaa caaaaacgat aaattcacgg tctttgattg atagattaaa
    32341 atcagttaca gaataatttt ctgcattgtc atatttttta tatacgtttt tcagagccat
    32401 ttctaccata atacgttcca cactttcttt tttagtttta ttaactattt aaagtataaa
    32461 tgaaagcgtt aactaacttc aatgtcatgt tgaacaagaa ttttttcttt tttttgtcaa
    32521 tgtgctagtt ttaagcttta ataaatatcc ataagaaata aaaactgata cactggagta
    32581 aataagtatg ttaacaatat caaaaggagt gtctcttatg aaaatcgctt tgatcgctca
    32641 tgaccgaaaa aaacctatga tggtgaaatt agcaacagcg tataaaacaa tattggaaaa
    32701 acatgaactt tttgctaccg ggacgactgg gcagaggatc acggaagcaa ccggcttgcc
    32761 gatccatcgg tttaaatccg gaccgttagg cggggatcag caaattggag ccatgatttc
    32821 ggaggatcag ttagatttgg tgatttttct tcgagacccg ctggctgcac agccccatga
    32881 accagatgta acagcactta tccgtttatc tgatgtctat gagattccgt tagctacgaa
    32941 tatcggaaca gctgaggtgc tactaagagg actggaagcc ggcttcctag attttcgaag
    33001 aatcgtccat gaaatagaca agcatccact ttcattttga tggataagcg tatggaaaaa
    33061 taacgtttaa tgttcgccta tatgtagcta taaaagctaa acaaactgat aatatgcgat
    33121 ataatacgaa cgtattggat aatataaaca ataatattag tttttcgtat ttgcagtaaa
    33181 tgtgaaaata tgctatagtt tctgtgggaa aagatcccaa aaataataca gagtagaaaa
    33241 taaagcgtta agtgctaaga ggatgggatg ttgcctcttg gacgaaggac gtaatgttcg
    33301 cggttttatt ttcgcattcg ctgcatgata cgatgtagca gctcttaaag gagatgctaa
    33361 aaatgaagaa acaccggtta gacgcacgta tgattgctat tatgggctta ttgattgcat
    33421 tgatggtcac tttgtcccga ctggtagcaa tcgagacccc atttattaaa atcagtgtca
    33481 catttattcc acaagtgatc atgggcattc tttttggtcc tttttggtca gggataggcg
    33541 cagttttagc tgatttagta ggaatggccc tcttctcgaa atctgcattc tttattggat
    33601 ttacattgaa tgcatttatt gaaggagcaa tctacggatt ctttttctat cgaaaagaga
    33661 tcacttggaa aaatgccatt ctggctacgc ttagtgtcac gctgatcatc aacttatttt
    33721 tgacaccatt atggcttgcg ttgatgtacc atgtgccatt gttcagctgg gtcgtttggg
    33781 cgccccgcct gttaaaaaca gtaatatggt taccgattca atcaattgcc atttattacg
    33841 taggacgtag tattccttac aaaaaaattt taagaagttt agcgatccac gctaaataaa
    33901 aaa
//
LOCUS       DAFKHN010000028        33440 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFKHN010000028 DAFKHN010000000
VERSION     DAFKHN010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.028"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            32..859
                     /locus_tag="LY912_001277"
     CDS             32..859
                     /locus_tag="LY912_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954986.1"
                     /translation="MNKRKWLFVCVAALFATAAYSQISFADSSTTPTTSQTTDSSTTA
                     TSDTDSSKNTAEETADSSTSSTESAESTSESSSETSEKLQEVEDTQVIKQNIHIQKII
                     SSNRINNQGRQVAHQEGVNGAKFIVYDITNILEEMTQDDNEKNQSVEIIESKLKDRAK
                     KLSYDQLKKVTEGETKTIDDQEGVIDFSIEVPANKKQAYYIVNESSPENISNSEDIIL
                     LTPISDEKGEFLTDVWLYPKSKKSEPKEEIKKVVSTGVKKNFFDNCWDFFTHLFFND"
     gene            869..1117
                     /locus_tag="LY912_001278"
     CDS             869..1117
                     /locus_tag="LY912_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954987.1"
                     /translation="MKIIKMLAFNLSFLAATILCCGLVFSQLSIYPRYQRLFVHFLNI
                     QHASMPLEVINMLLINPIFMASLFLLAGLVTWVLGKKE"
     gene            1160..3259
                     /locus_tag="LY912_001279"
     CDS             1160..3259
                     /locus_tag="LY912_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBM6954988.1"
                     /translation="MENKIHCTTGRVFTLVLFLFLLLFARGTAVQALEKVDPSQIREN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNVKLDFKYSGSKTKVALSEPQPEINSKMRSMRAAGIELNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKSTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLDNA
                     ANYGRDYILQLHMKAKNDAKGIAPNVATVTFNNDPNKGIQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVEA
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNLRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLQSEKNIDNQAVAAVENVSNKTNVVTIGVDPNLPQVIVPRTGSTHLVTILVVS
                     LVLLVLVTLSYVALKFN"
     gene            complement(3295..5346)
                     /locus_tag="LY912_001280"
     CDS             complement(3295..5346)
                     /locus_tag="LY912_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBM6954989.1"
                     /translation="MKLLNPKTVLAIGTFAATLGFAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNANKVLNDSKAT
                     QKQVDSAKNNLDSAYKGLKKKPAPTVNKAELQALYNRVKSTAKGDFTEESWNDFQTAL
                     SNAKKVLDDSKASQAQVNNAKNSLDAAFKGLQHKPETPYMVTINHIDNQTGQVIATDQ
                     AQVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSQTITGNTTITFNYNQVHQINL
                     LCNNNYKNEGRVDILKEQIINVTHGESVTLTAPAIQGYVLDDRVEPTNSVTLNNVTES
                     QNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFSTPWKNMTDQNYFLCRNDD
                     PSISVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELVWLNNYRQQNGAAPM
                     QFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVDEI
                     LSDTGAVNAMIMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANPIF
                     K"
     gene            complement(5466..5675)
                     /locus_tag="LY912_001281"
     CDS             complement(5466..5675)
                     /locus_tag="LY912_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954990.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAIKLNKLAEETIDTNASTK"
     gene            5863..6321
                     /locus_tag="LY912_001282"
     CDS             5863..6321
                     /locus_tag="LY912_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954991.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLVNNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGIDLFI
                     GKTALIVPYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            6318..6560
                     /locus_tag="LY912_001283"
     CDS             6318..6560
                     /locus_tag="LY912_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBM6954992.1"
                     /translation="MIASLFIYPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            6578..6880
                     /locus_tag="LY912_001284"
     CDS             6578..6880
                     /locus_tag="LY912_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954993.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAGVAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILGAASIITSLFGLFGQTPQGL"
     gene            6950..9004
                     /locus_tag="LY912_001285"
     CDS             6950..9004
                     /locus_tag="LY912_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954994.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEESDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESIWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NGLYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIRERKEEFYQGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQRELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDPSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            9004..11613
                     /locus_tag="LY912_001286"
     CDS             9004..11613
                     /locus_tag="LY912_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBM6954995.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMNMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     INSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYKEKQIDRLQEYLEKLRQNEEITEVIR
                     KRLLLEAEKAVKE"
     gene            11610..14000
                     /locus_tag="LY912_001287"
     CDS             11610..14000
                     /locus_tag="LY912_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954996.1"
                     /translation="MIIGGIFSGIADWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSNLNDIRKNGFGN
                     RKDGTPDNGEEQPDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTAE
                     DLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSTAGNVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVV
                     TREAAPQPIQKVHTGYKPANVAFTAPTKINVTRETKNRNNELKEQLLRDIKQDIKP"
     gene            14052..14384
                     /locus_tag="LY912_001288"
     CDS             14052..14384
                     /locus_tag="LY912_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954997.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            14385..14978
                     /locus_tag="LY912_001289"
     CDS             14385..14978
                     /locus_tag="LY912_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6954998.1"
                     /translation="MRVKGQNSVDKKSIFQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFIIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            15141..17165
                     /locus_tag="LY912_001290"
     CDS             15141..17165
                     /locus_tag="LY912_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBM6954999.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKCFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            17165..18370
                     /locus_tag="LY912_001291"
     CDS             17165..18370
                     /locus_tag="LY912_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBM6955000.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAADSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPSLNSSKK"
     gene            18386..19030
                     /locus_tag="LY912_001292"
     CDS             18386..19030
                     /locus_tag="LY912_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955001.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            19041..19847
                     /locus_tag="LY912_001293"
     CDS             19041..19847
                     /locus_tag="LY912_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955002.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            19869..20099
                     /locus_tag="LY912_001294"
     CDS             19869..20099
                     /locus_tag="LY912_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955003.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICQEVHLSNTTISE
                     LKNGRKSLDTLKFRSFEALYVAAKKYFTADNK"
     gene            20645..20920
                     /locus_tag="LY912_001295"
     CDS             20645..20920
                     /locus_tag="LY912_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955004.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            20962..21384
                     /locus_tag="LY912_001296"
     CDS             20962..21384
                     /locus_tag="LY912_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955005.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            21403..22995
                     /locus_tag="LY912_001297"
     CDS             21403..22995
                     /locus_tag="LY912_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955006.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            23007..23342
                     /locus_tag="LY912_001298"
     CDS             23007..23342
                     /locus_tag="LY912_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955007.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            23489..23683
                     /locus_tag="LY912_001299"
     CDS             23489..23683
                     /locus_tag="LY912_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955008.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            23715..26087
                     /locus_tag="LY912_001300"
     CDS             23715..26087
                     /locus_tag="LY912_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955009.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     TPTDSVKEKETDHFYRVEFNENDPAKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELARLCEQSPEKEQEQTVKNEPISKV
                     QNEIKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGQTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     ATWTKNSQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVLEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            26148..27608
                     /locus_tag="LY912_001301"
     CDS             26148..27608
                     /locus_tag="LY912_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBM6955010.1"
                     /translation="MTEKKMSLIDRCKQMDIVDFARNNGLAVANKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPDWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPREYKVI
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEVISLKD
                     ICREVAKELKDCERSNGTYDFDRFYQGKGDINSQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIHQQEIRKQKRAMLFQQGRQQERE"
     gene            27619..29823
                     /locus_tag="LY912_001302"
     CDS             27619..29823
                     /locus_tag="LY912_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBM6955011.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVTAQNGIFDAKLDPNETQATQEAFEAYLKEKGVQVGKQPGTILEVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EHAYLLDHLDEYKHFLKAESFPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYEK
                     LTPLQQAIYDQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGETVTVDLQIFEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLTKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQATDFGATLQEVKV
                     ASEKQEAARHLGSCPKCQEKEVILYQKVATCTSEACDFKLWVTIAKKKLTATQLKEII
                     QNGRTSQPVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTTYKRKVRRKTS"
     gene            29844..29993
                     /locus_tag="LY912_001303"
     CDS             29844..29993
                     /locus_tag="LY912_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955012.1"
                     /translation="MRNTTHKEQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     LELDR"
     gene            30069..30662
                     /locus_tag="LY912_001304"
     CDS             30069..30662
                     /locus_tag="LY912_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBM6955013.1"
                     /translation="MKDKVKCIFEKYNGNLSLKDARNEGLSPMTLDRLAEKDKIEKIA
                     SGFYTLKDSFVDELYLAQSIYTRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     NLDQYAIQPHYTNKENFELGITEAESFYGNKIFVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMNILKSPKEMTLYMLPLY"
     gene            30678..31577
                     /locus_tag="LY912_001305"
     CDS             30678..31577
                     /locus_tag="LY912_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBM6955014.1"
                     /translation="MTPTQFKAKTRNVAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTAAPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAFLENARVPFKLDITSGDSIIPAALIYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGIDNSRMKDFYDLYMIPKLERIDEINLYKSVQGTFKE
                     RNNQSVFKNLYNQEMPQLMKNEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEEVERKQNFKRSQQMNQEMER"
     gene            31580..32065
                     /gene="ssb"
                     /locus_tag="LY912_001306"
     CDS             31580..32065
                     /gene="ssb"
                     /locus_tag="LY912_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBM6955015.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVTTFTLAVNRNFTNQSGNR
                     EADFINCVIWRKPAETIATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            32431..32691
                     /locus_tag="LY912_001307"
     CDS             32431..32691
                     /locus_tag="LY912_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955016.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            33132..33338
                     /locus_tag="LY912_001308"
     CDS             33132..33338
                     /locus_tag="LY912_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBM6955017.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT        12246 a         5405 c         6764 g         9025 t
ORIGIN      
        1 tatttataaa aaaaataagg aggagatcgg aatgaataag agaaaatggc tgtttgtttg
       61 tgtagcagct ctctttgcaa ctgcagctta ctcacagata tcttttgctg atagcagtac
      121 cactccaact accagtcaga caacagatag ttcaacaact gcaacaagcg acacggacag
      181 ttcgaagaac actgcagaag aaacggcaga ttcaagtacg agttctactg aatcagcgga
      241 atcaacgtca gaaagttctt cagagacttc agaaaaactg caagaagtag aagatacgca
      301 agtaatcaag caaaacattc atattcaaaa aattatttct tcgaatcgaa tcaacaatca
      361 aggaaggcaa gtagctcatc aagaaggtgt caatggcgca aagtttattg tctacgatat
      421 cacgaatatc ttagaagaaa tgacacaaga tgataatgag aaaaatcaat cggtagaaat
      481 aattgagtca aaattgaaag atcgagcaaa aaaactttca tacgaccagt tgaaaaaagt
      541 gactgaagga gaaaccaaaa caattgatga tcaggaaggt gtgattgatt tttcaattga
      601 agtacctgca aacaaaaaac aagcatacta tatcgtcaat gaatcaagcc ctgaaaacat
      661 ttcaaatagc gaagatatta ttttattgac acctatttca gatgaaaagg gtgaattttt
      721 gacggatgtt tggttatatc ctaaatcaaa gaaatcagag ccgaaagaag aaattaaaaa
      781 agttgtatca actggtgtaa agaaaaactt ttttgataat tgttgggatt ttttcactca
      841 tttatttttt aacgattagg atgaaatgat gaaaataata aaaatgttag cttttaatct
      901 atctttttta gccgcaacaa tattgtgttg cggtttagtt ttttctcaat tatcaattta
      961 tccaagatat caacgattgt tcgttcattt tctaaatatc cagcatgctt ccatgccact
     1021 agaagtgatt aacatgctct taatcaatcc aatttttatg gctagtttgt ttcttcttgc
     1081 aggattggta acgtgggtat taggaaaaaa agaatgagaa gcttacaatc gtttaacaaa
     1141 ataatagatg gagggcatta tggaaaataa aattcattgc actacgggaa gagtatttac
     1201 tttagtgttg tttttgttcc ttcttctttt tgcaagggga actgcagtcc aggccttaga
     1261 aaaagttgat ccgagtcaaa tcagagaaaa taataatctg gtactttatc atgatagtga
     1321 ttcattgaga aatatcgaag taactgggat caatggattt aagatactag atgagtattc
     1381 aactaaaaaa caaaaagtac ttgcttggcc aaaagtcaaa gatttgaaaa gcacgtcaaa
     1441 aattgttgcc cattatcaaa aggtgggcac ttatctagga aaagaaattg attgcgacgt
     1501 aactttttct aattttgtag cgcacgctgg ggttaaccaa gacggattag ctaaaacaat
     1561 taatgggaaa aagtattata attatttgct ctttgataaa aacatttatc gaggcttttt
     1621 catgcagtca atcaacgtta tgaatgtaaa actagatttt aagtattcag gatcaaaaac
     1681 aaaagtagct ttgagtgaac cacagccaga aattaattca aaaatgagat cgatgagagc
     1741 agctggtatt gagttgaatg atacatttct atctatttac agtttaaatg gacagtatca
     1801 gcaacgtgtg tcttggtata atgacaataa tgaatctgtc ggtgaacgta atattgatat
     1861 gagagaattt gttgggtatg aaaaaatggg tagcttacct tattttgtca caacagatac
     1921 agcatgtgca gaatacaaag ctcctgcgtt atcaacaaac aatttaactt caaaagtagt
     1981 gggaggacgt gcagaaaagg cttatagctc gaatgatcat ttcaccgatg ttgtaggagc
     2041 tgatacttat cacagaagtg gtgtaacgta tacgcttcaa ggcgcttccc caacattcat
     2101 gattggcgca aatacgaata gtatgatgtt tagctttgat actgcattgc tatggacacc
     2161 acaaccatcg aagtctacaa aagaagtgtt taacaaagct aatactgaag aggcagcaca
     2221 caatattgac aaaaaagtga ttccacaagg atcagatgtt tactatcata ttcaccaaaa
     2281 gtttgatgca ttaacagtca acacaatgaa caaatacaaa tcatttaaaa tcactgatac
     2341 ctttgacagc aaaaattttg atatggtatc ggatgggaaa aactatgatg gcgcattgtg
     2401 gtatgttgaa gcgaatggga cttggaaaaa agctgataca ggaggaaaat taactgtatc
     2461 aggtaataca gtcacttata ctgcttctga cagcttttta gataacgctg caaattacgg
     2521 tagggattat attttgcagc tccatatgaa agcaaaaaat gatgcaaaag gaattgcacc
     2581 aaatgtggct actgtaacgt ttaacaatga tccgaacaaa ggaatacaaa aaacaaatac
     2641 agtagaaaac tatttctctc ttaaaccaaa taaaaaagtg gaacaagatg ggaaagatgt
     2701 tgatggtcga aatgatggta aaaaaggaac gcctacagct cctttaaatg caggatctga
     2761 agtacaatat ctagtcacac aaaaatggca tacaaaaggt gtagacattg cgtcagatca
     2821 ttacaagcaa tttagtattc aagatccagt ggaagctcgt ttgacgtata aagaaggttc
     2881 tgcgcgagtg atagatatga gtacaggaaa agatattact tcagaaggta cactaaccta
     2941 tgatagcaat ttaagaacgc tgaaatggga agcttccgct gatttcttaa gtaaaaatct
     3001 tttagatgga cgagaaattc aactgatatt tacagctaaa actccactac agtcagaaaa
     3061 aaatattgat aaccaagccg tagcagcagt agagaatgtt tctaataaaa cgaatgttgt
     3121 aacaattggt gttgatccta acttgccaca agtcattgtt cctagaacag gttctacaca
     3181 tttagtaaca attttagtgg ttagcttagt attacttgtg ttagttactc ttagttatgt
     3241 ggctctgaag ttcaattaaa caaaaaaaca aggctgaaaa tcagccttgt ttttctattt
     3301 gaaaattgga ttggcactaa taaatacgtt gtctgaagaa agtgatccat ctgcagaaac
     3361 ttcataagca tgagataacc caacgatgct ttgattgttg taaagtaagt ttgcgttatg
     3421 agcagcgcta tctttccaca taatcatggc attcactgct cccgtatctg aaaggatctc
     3481 gtcaacgtaa aggtagaaac tattgatatt ttctccttta gcgccgtagc agcctaaact
     3541 ttctaagaga tcttggaaag taccgccgcc aggtcgataa tgactgaagc ttacttgtaa
     3601 ttcttttgca cgtatatcag cagcttgttg aacgatatca ttaaattgca ttggagctgc
     3661 accgttttgt tgacgataat tatttaacca tacaagttct ttttgacgca catagttgtt
     3721 taaatcactt aatgagatat ttttgtattt gaacgtgatc gttcgatttt ggtcaacatt
     3781 attgattact cgttggccgt ttttatctac gctaatggaa ggatcgtcat ttctacacaa
     3841 gaaataattt tgatcagtca tatttttcca aggagtagag aagctatccc cttcgtatac
     3901 tgtttttgat tcactagaga gaacagcgtt ggtatcagca tttacatgat taacagtcac
     3961 attaaattta cgagtgtagt tgaaaatata attttgactt tcagtcacat tgtttaaggt
     4021 tactgaattt gttggttcta cccgatcgtc taaaacatat ccttgaatag caggagcagt
     4081 taaagtgaca ctttcaccgt gagtgacgtt gattatctgt tctttcaaaa tatcaactcg
     4141 cccctcattt ttgtagttgt tattgcacaa caaattgatt tgatgcactt gattataatt
     4201 gaaggtgatt gttgtattac ctgtgatcgt ttggctttga gtatcattac caatcacttt
     4261 gtagctaaaa ttatctttag cgccttcgct atatttaaat gcttttgcct tagcggtgta
     4321 agtagaacca gaagtcactt gtgcttgatc tgtagcaatc acttgacctg tttgattgtc
     4381 aatatggtta atggtaacca tatatggcgt ttcaggtttg tgttgcaacc ctttaaatgc
     4441 agcatctaga ctatttttag cattatttac ttgggcttga gaagccttag aatcgtctag
     4501 tactttttta gcattggata aagcagtctg aaaatcattc caagattctt ctgtaaaatc
     4561 tcctttagca gttgatttta ctcggttgta taaagcttgt aattcagctt tattcacagt
     4621 aggtgctggt tttttcttta atcccttgta agcagaatct aaattatttt tagcactatc
     4681 cacttgtttt tgagtcgctt ttgagtcatt taacacttta ttagcattat ttaaagcagt
     4741 ttgaaatgcg ttccaggtat tgtcggtata gtcacctttt ttcgttccct taacgctcgt
     4801 ataaagagct tctaaagctg atttattcac tttgggttta gaggtgtcag cgccatacca
     4861 accgatacct tcgtatttcc agccatagtc tttggttaac cattgtactt ctttccaact
     4921 tgcagtgtag tgatgtgagc cagattttac accaggaagg aaaaggcggt agatcggttt
     4981 attatttttt tcggcagaac gccaggcagg cccttcataa gtccagccgt aatttttagt
     5041 caaccatttc acttcatccc aactagctgt gtaatggtga tcacgaagac ctttattgta
     5101 taaacgatag acaagatgac caccgctagt cggtgcttcc caagcggggc cttcataatt
     5161 cccccactta atcttcacta ggtgatcacg ttcttttgtg ctagaggtgt aaaaatgttc
     5221 atggttattt ggattataaa ggcgatacat gacgttagtt gaagcagcat cagcagatcc
     5281 agcgaaacca agtgtggcag caaatgttcc aatagctaaa acagtttttg ggtttaataa
     5341 tttcatattt tcaactccta aaaattagtt aaaatcgatt acaaaatcat tatatatcgg
     5401 taaaccgata tggtcaataa aaaaattaag aaaagcctca tgtatttctg gcttttctta
     5461 atttgttact tagttgaagc gttagtatca atggtttctt cagctaattt atttaatttt
     5521 atagcattga tgaatctcat attgtctata ctagagcgct tatttgcgag atcactgacc
     5581 gtagttaaag gtacgccaga ttctatagat atagaacgaa ctgatttacc actatcaaac
     5641 agcaaccatt cgattttctt tttatcagcg tacattgcaa tgctccctct tgattttttc
     5701 tttattatag ctcttttttg taataaatca caatatcaag agagaaagtt tttatagaaa
     5761 ggtgggaaat tatgagtatc cgttccccgt gtatcaaaat gaggtttgtt gctactttcg
     5821 ttatttgata tactaaaata aaacaacgaa agaagaaata aaatgaagaa aaagcaacta
     5881 tggtttgtct ctatgtttgc aatatttttt attattttaa gtggatgttc aagtaataag
     5941 aaatcggaag ctaaagaaga taatagttta ttgcaaccag gaactgtttg gaaagaagaa
     6001 gtaggtggtc ttgttaataa tttgaaaatt atagacgata caacatggga atattccgaa
     6061 agtgtttggc atcctgaaca agtacaaata acagttgaga agctaaaaga ctataaagga
     6121 ttagaaagat ataaggtaat cgattcaggt ggaatagatt tattcatagg taaaacagcc
     6181 ttaatagttc cctataacaa agacggttta gaaacgttta aatttattcc aacaaacgaa
     6241 aaagaacatc gagataaaag tgaaatatta aaagaataca gtactaaatc tggatacaag
     6301 ttacaaaaga ctagcgagtg attgctagtc tttttattta tcctgaagga ggaatcacag
     6361 tggcaaaagc taaaacgcca tttgaaaaag ccgcgtctaa aatcttagaa cgtcgcggtg
     6421 tatctgaaac acagtggaaa caagaagtcc ttgaaaaagc acaatttgac ctattacggg
     6481 gaaaagacaa ggacttagaa ggatatatct atcaacgtga acgtgaaaag cttgttttcg
     6541 atgaaattat taaacactaa aaggagcgaa caattttatg tttgaatcaa ttacaatgaa
     6601 ttttttaaca caaccgaaag tagtagctgc ggttgatatt tttagagcat tacaaactgc
     6661 agcaactagt ttaaaaaaca atttgatgat ttttgctggt gttgcggccg ttgcttccat
     6721 tgttattggg gggcttttct tcctatttgg acgaagagga gctgaaaacg ggaagatgca
     6781 cgtaggttat gtattgatgg gggtaggtgt tattctaggg gctgcttcta tcataacttc
     6841 gttatttgga ttatttgggc aaacacctca aggattataa gaaagtaaaa aagtaggagt
     6901 aagaagtagt cgatactttt tactcctttt ttatgaaagg agaatattca tgtactttac
     6961 gattgcaggc aataccaaaa cagataaaga gttaattaaa aaagcaacga aggaagtagg
     7021 aaagcggact tcttttttac cgaaaacaat taaatattct gtcattgaaa cggaagaaca
     7081 gctacatgtg ttagggaaag tactggaaca cgaaagtcga tcttctgtta agttgactct
     7141 cacgttacat gacacagaag gaaaaataga gaaagctggt acagaatacg tttttggccc
     7201 gctggattat caaatttcag aaggtttcta tcctacattg atggatttaa tccgccttga
     7261 tgtgtttaaa gaaacggatg aaactatgag tgtggaagag tcttatcgaa acgaaaaact
     7321 tttacaagtt ttagaagaag agttagagag cgaccaaaga aaagtgaatc aagtgagtga
     7381 agtcgaagta aatgaagaag taccatggga acgaccaatc tttccaaaga aggagtcaaa
     7441 agaaaaagag acagtctatg ttgacgaaca agctgatatt ccgactcaga aatcgatatt
     7501 tgaggaagag agcgatgtga tgggtcaatt ggaggtagat ccctttgaag aaacaatgga
     7561 ggatgaagag acggccgaag tagaagttga tccagttgaa gctaatgaag agtcaatatg
     7621 gactgaaggg gattctcagg aatatattga accacttatc agtgaagaag tagagaaaaa
     7681 cgaaacagag atacaaaagg caactgtatt tgattatatt ttggatcaat atccgccaga
     7741 gcatgaatgg atgaaagaaa aaaacaaatt atttttaaat gggctttatt cgaaatatca
     7801 attaccccaa acctatcaag catttttaga gagtaaagaa gaattaatct cacagggtaa
     7861 aggcacactt ttagaacagt tagagtctgt ccaatcaaca aattggcatg agcttgcaca
     7921 agaagattta ttagccacct ttgaagaacg tcaacaagaa acagatcaag aaattaatga
     7981 gtatgcgacg gaacagtcgt ctaattggga gaaagcaaag gaggaactaa ataaagaaga
     8041 acagcgagtg attgaagaag aagtacaaaa aattaaagag cgatacgaaa agaaacgcga
     8101 caatgcgtat tccttgtgtg tagaaaagat caataatttt actcagacga atcaagaagc
     8161 gttatcgaaa gaaaaagaaa acttgttaaa agaacgtata agagaacgaa aagaagaatt
     8221 ttatcaaggt ttgcgtacag ataagctaaa gattagcaaa gaattaaatg agcaactgaa
     8281 taagctatat caaacaacga ctgaagttct tatggaaaaa cacgagcaga tccagcaaga
     8341 attacaagta caaattccaa aatggaaaaa agagtatgaa attcaacaac gagaattgaa
     8401 agaacaagaa gaaaaacaac ggcaaaaaga aaaagagcgc gaacaattag aattaaaaaa
     8461 acgtgaacag gatcttgcgg aacaaaaaat ggcgatagaa aaacaacggt tagagcaaga
     8521 aaaggaaaaa gaagcagctg ctcgtaagga acgtcaagaa caaatggata cattgcgaca
     8581 agcacagtta aattatctag cacaacctca accagtagct gctgttcaaa cgccagtgaa
     8641 caaccaagca aatttaactc cttcaccaca gcgttccttt aacggatgga tggtgggatg
     8701 tattgcaagt ttaagcttgc ttctaggtgg aggaacagta tttgctttta atcatatcaa
     8761 tcaatcttca caggctgatt ctgtggccac aacgacgtca atcaaggaag aagcccaaga
     8821 acaagcaaga aaagagtatg aacaacaatt agaagaatta ttgaatcgta ccaatcagtc
     8881 aacaacagag tcaagtatgg aaaatagcaa agagagtgat cctagtaagg ctaaagaagg
     8941 atcaagcgat tcaactgtac aatcaaacac ttccgaaagt tcagaatcaa atgaggtgaa
     9001 ataatgcgtg ttagagaaac aacgagacga aaagacaaac gattcaattt agaaaagaat
     9061 aggtatcttt ctcatttcta tcgctatact ccttcaggag aagagctacc agaaaaacat
     9121 gacaaacgta tttctcaaaa gattttttat agtggcttag cttatcttcc tttaaactat
     9181 gttgttacaa gaataccaga agcatttcat cgatttgaga ttattccagg aagtttacaa
     9241 ggagtgaata tttttcagtt acaagaaatg ccacagttat tccattttga ttcaactggt
     9301 ttttggaatc ctttgacccc aacaacaagt ttaggcacac gtttagttgt ttctacgatt
     9361 tgtgttgttc cagctgtact tatgggattg aaaatgaaca tgtggtttcg tcctctagca
     9421 gatgggcaaa aaggagataa ccgattaaaa acgttaaagg aaatccagca aatttatccg
     9481 caaataccag aatcaaaggg aggttttcct ggttatggcg gaataccaat tactcattat
     9541 aaaaagtact ggtatattca gacggataca gtaaatactt gtattgttgg tacttcccgt
     9601 tcagggaaag gacagataga agttttagca accattgaca atttgtctcg tgcagaaaga
     9661 caaagttcaa tggttgttaa tgatccaaaa acagaattat atgttgctag taaagatgaa
     9721 ctagaagcta gagggtatga tgtgtatgca tttaatatca ccgatccact gcaatcaatg
     9781 agtgataatc cattggcact catcgtgaaa tactggaagc gaggagacat agacacagcg
     9841 acacagttaa ccaatacttt cacgaatacg atttattatg atgccaacgc ttcagacaat
     9901 aaatacttta acgaaaatgc gcaaaaagct gtcaatgcgc ttatttttgc gttattggaa
     9961 caagcggatc agacagggga ttactccaaa ttaacaccga ataatctcgt cgaacttctt
    10021 tctgagattg gtggttttaa ttaccaagat cctgataatg aattcaagca gctcaatgct
    10081 ttagatgaat ttatgaatca gttaccacct ggaaacatag caaaaaaaca atatggggca
    10141 acaaaaattg gttctgataa agcgaaaggc aacattctat cgacagcaat cacaggacta
    10201 aatccattta cactgacgaa aattgcgaaa atgacttctc aatcaaccat tgattataaa
    10261 tccattggtt ttccgaagta tttggatctc aaactacacg agagtctgtt aaaccagcga
    10321 attgttgtag agttttatca tcaaggaaaa aaatttcatg aggaacgtgt caaagtaggc
    10381 tatagaggtt tttgtgaaat taactttgat tgtcatttag aacagggaga tcatgtttgc
    10441 ttaaaatatg atcatcgagg aaaagaatat gttgcttggt atgagttttc tcaaagagta
    10501 ttgaaagacg aagagggaaa tatcgtttat cgaaaaaaac gaggagaaac ccatttgcca
    10561 gaattagaaa aagaagccgt tctaacatta gatgaggata aaagtaactt attagtagag
    10621 tctattcgga tgcactatac cgataaacca atggctattt ttatgctcac acctgattat
    10681 gatccatcta accatatcat tgttagtatt tttcttagtc agttgtataa agaattatct
    10741 acgcaatgtg ttaagactaa aggagataaa tgtcaccgta ggattcattt tattttagat
    10801 gaatttggga atatgccacc aatggataat atggaaggaa tcatgacagt cacagctggt
    10861 agaaacatgt tgtgggattt gtttatccaa tcctatcagc aactttatgc gaagtatggg
    10921 gaacaaaacg cagcgattat caaagaaaat tgtcagacac atatttatat tatgtcgaca
    10981 gatgataata ccatcgaaga attttctaaa aaagtgggga ataagacggt tgaacaagag
    11041 aacagtacca tcaattcatt aggtatgaat actcatatca atcgcaatgt tgattcagat
    11101 cgtatcttaa ctcctgaaag aatttctact tttttagaag gtgaaacgat tgtactcgct
    11161 cctttaaaac gacaagattt gaaaggtcat aaaatacggc cgtatcctat ttttaatcat
    11221 ggggaaacga atcttcctta tgcttatcaa tatattgaag atttcaatcc atcgtgggat
    11281 atcaatgata tagacataca ttgtacacat gcggacttgg atcttaaggc tttacaaatt
    11341 gattacgatt attttctacc tgatatctat gcacgtcgac tttatcacaa tatgcacgat
    11401 caaatagaag aggaagctaa agaaaacatt tttattaaaa tcgttcaatc tttagacaac
    11461 tcaacggcac aaaagttact tattcaattt tataaagaga agcaaataga tcgtttgcaa
    11521 gaataccttg aaaaattgcg tcaaaatgaa gaaattacag aggttataag gaaacgactt
    11581 ttgctagaag ctgaaaaggc ggtgaaagaa tgatcattgg aggaatattt tccggcattg
    11641 ccgactggtg gtcaggctta tttggagatg gggatgcaga tcccaaaacc gtaacgaaag
    11701 tcttacaaga ttatggtaat tatctgcagt atcaagatgt attcagttgg atttgtaata
    11761 cttttttatg gggtttgatt aaagggttat ataatctcaa tactttacta gaaaaaacaa
    11821 tttatcaaag ctttgattta aaagacttat tgaacgccgc tggtgttaat gaactgtttc
    11881 aaagtttgat tagtaaggta ttggctcttt tttgtgtcgt cacattaatt tatttaggct
    11941 taaaattttt tatgagtaaa catccaccaa aaatcaaaaa tatcttggtt aatctattta
    12001 tggccatgat tttgattttt ggtggtagtt ctttaatcga tgaagggcta aatattagta
    12061 aaaactttta cggagacgtg actgcagcaa ataaagcaga taaaactggt tcacctgctt
    12121 ttcaaattat tcaaaataat gtgattgatg tgagtacgtt actagaaaat gatccgaaca
    12181 aagtagaaca cataccaaca gataaaagaa atgctctcac ggcgaaaaat tttaaaacag
    12241 cgaatatcaa tgggattatt acacctgatc aagctaagaa aatgtctgaa tcaagtgata
    12301 ttagtacagt acaaaaagat cggttaaagg cattacagta tcgactagag ttagacgata
    12361 atgggaaaga aattcctgtg caaatcagtg atgaaggctt agccaaatat gtttatactt
    12421 cagggtatcg tcgatacatt agtagtccag ggattatttt agctggtgaa tcttctttgg
    12481 cggtggccta tttatttatc ttgtttacga ttgttacttg tattattgag ctggtattta
    12541 aaaaattcta tttagtgatt gccgcgtcaa cggactttga gacaggacaa cggatgaaaa
    12601 gtgctataga agatatttct caatccttct tgttattggc atttacaatt ttagaattac
    12661 gaatctatac attaatgctt tcaggtattg gtgatttgca tgcggcagga aagatcaatg
    12721 gattcttgta tgttgtcgct ttgattgtac taaccattgc gctattcaaa ggctctcaat
    12781 cagttacgaa aattttcggc gttgatacga gtctgaaaaa cggcagcaat tctcttctta
    12841 gcatgtttgc cttaggaaat attgcgaaaa atgtgggtag tggggctaaa aaccttgcaa
    12901 gtgctggtaa gagtggttta agcaatttaa atgatattcg taaaaatgga tttggcaatc
    12961 gaaaagatgg tactcctgat aacggggaag aacaaccaga cgataaagct acaacagtac
    13021 ctaatagtaa aaagacagtt tccgaaatgt tcgggaaagc gaagaatggt gtttctaaag
    13081 ccgcagaagg tcttggttac gtcaatgaac gtgggttaaa aggaacagct gaagatctta
    13141 cagaaaaagc caaagacacc ttagaagaaa aattagacgg cacgagagcc aaagaattgg
    13201 ctgaagctgt gaagaatccg tccgaagcac tagaaaaaca aaaagaaaaa gcttcagaag
    13261 tcaaagaagg actaaaagat gcgtatggtg aaggacaagt caatgcagca gtgaaggcaa
    13321 atacaacaag tgaaaaagaa aatcaagaag gtgcagcgat tccttcagcc aaagatcacc
    13381 aagatgagtt acattctaac gaaaattcga tcggagaaaa agattcagaa gaaggacaac
    13441 atggtcagtt accaaagacc gatccagaac aatatcgtta taaatctaac attaattctg
    13501 aaaacgaaaa acgcatttca gatttaccaa aacgaaatca agaagtacaa acggatgagg
    13561 attccatcga tctgccaaat gataatggca tcgaagttgg aactgaaaaa tcaacgaaaa
    13621 ttggtttgcc taagacacaa aatttaccaa tgaaagatag tcgtttgaat caattcaagg
    13681 agaatgatca aagctttgtt caccaatcaa ctgcaggtaa tgttcaaatg aaaccaagtc
    13741 gtttgcctga aaatggaaat ctgacaactg tttcttacaa tttatctgaa agtggggaga
    13801 cagggaatgc gtccgttcaa aatgttgtga caagagaagc tgcaccacaa cctattcaaa
    13861 aagttcacac aggttacaag ccagcaaatg tggcatttac tgcaccaaca aaaataaatg
    13921 tgacacgaga aactaaaaac aggaacaatg aattgaaaga acaactattg cgggatatca
    13981 aacaggatat caaaccataa aaggcctaca agttaggcct tttttctatg tatgaaaagg
    14041 agaaatcatt tatggataaa tatattaaca tgaaaaatcc tccaagattt agtggggaat
    14101 ggaagttttt cgcctttttc tttttagatc tattaacgct tggtggttgc tttttttggg
    14161 cgaaaatagt caataatctt gtccacttac cactcttttt tgcactcttg aattatggct
    14221 tatggattgc gatagctcta gtgattgttt ggcgacccta taataaccca ggtcaacgcc
    14281 agatttttgc gattatcgaa tctatttttt ttacggacaa gaaccattac catgccctag
    14341 atcctaaccg aaattatcat ggtacgtata aggaggatga ataaatgcga gtcaaaggac
    14401 aaaactctgt tgataagaaa tccatttttc agtttggaaa accagaagaa cgatcgatct
    14461 tggatttatt tccttataaa tcctgtacag aagagggggt cttagttact aaagaagatc
    14521 attttcaacg ttattatcgt gtagtttcca ctgacgtgga gggattaaat gaacaagaga
    14581 aactggaacg aatgaatcag ttgaccaccg tcatgcgtac gtatgtgcca acaattaagt
    14641 tagttagttt gaccacagaa acggatctaa cggagcaaat cgtacaaaag cggcagttat
    14701 tagataagaa tcgtatggaa caatccttag gaagaaatct acagcgatta agaaaatatg
    14761 aaaagaaatt agtagaggaa atccaggaat tgaaacgagc agaacaagaa cgtcctgact
    14821 taagcttctt tttcatcatt gaaggaaaga caatcaagga tttacaaacc agaaaccgtc
    14881 agttaatgcg atctagtggc attttagggt taaaaccact ctacaaaaaa gaattgatca
    14941 agattcttta tcgaatgaat aatatgaatg atgagtagga atggagaaga gagaatgaaa
    15001 tatccgttga tatggttaga aaaagatgtt ccgaaggaag agaccactag aaaatttcct
    15061 cacactttaa gcctggataa gttgggaaaa gggcaatctt ttcaccaagt aaagaatcaa
    15121 acaagaagag gtgactgtac atgttagaag cgattaaaac agctttttca ccacaaaatg
    15181 atcaaaaagt acttgatcca ttaaagcaac taggaaatcg ggaaatcgaa attttaaaat
    15241 ccaaagggta tgatttagat tttttaaaac aagtgatgcc acaaggtgga ttaaatttcg
    15301 atgaagagta tgtgacctat ggaaatggtt attcacggtg tgtgacagtt tatcactaca
    15361 caaaaaatcc aacacttttt tggttggcca atctcatgaa caatcctcat acagtggcca
    15421 cactcgatgt tagcacagat gaaaagcaaa aagtgattga tcaaatcaat cgtgccttag
    15481 atgaattaaa tgatcgatca gataacgagc gaaaagcgac tgaccgaaat aaaagcgcag
    15541 aagaatacct ggaactagcg gaatatgccc gaaaattgac ttctaatggg gaaatttcta
    15601 aacaagtcaa agtgagagta catgtttacg gaaacacgat tcaagaagta gatgaacgag
    15661 cgcaggaact gattgaaaat ctcaaaggga tggattatcg tgcggtgacc tatctgcata
    15721 aaaccaaacg agattggcaa tcgatgttta ccatgttcga tgaacaagct gaatggttcg
    15781 gaaatatcaa agggcaatca ctaccatcgt taaacattgg cggaggtttc ccgttccacc
    15841 accaaacgct aaaagatcca ggaggtacac aatatgggga aaccatgaca ggcggcccat
    15901 ttgtctggaa tgcgacgtat aaaaatagtg tacggttgtc tactaatacc ttgcttctag
    15961 gaatgatggg agctggtaaa tcgaccgttc ttaaaatgat cgcggaagcc catttagctg
    16021 caggagactt tatttggggc tttgaaaagg gaaaagactt tattcccttt ttaaaggaat
    16081 ataacggcat tatggtgcgt ttagacggat ctgacgggat gatcaatcct ttagaaatat
    16141 ttgccacacg tacgtatgat gaagcttcca gtttatatga cgatggatca gtcaaagatt
    16201 tgaagatcaa tgaagcagcg tcctatcaaa cgcacttaga caaagtggtc tatcaggtac
    16261 agttagtgag tcctcagcta aaaggaacga tgaaagcaga atttaagacc tatttaaatc
    16321 gtttttatga agagtatgga acagtaccac gcggctttac ttcctcaaat tcgcgttcaa
    16381 atactgatac gcaagtcaca ggtaaagatc cagaagctta tccgacgttc aaagaatttt
    16441 tagacttttt aggacaactg gaattaccag gtgcttccca agagaaaaag aatcgaaaag
    16501 aagaaatgga atccatcgta gaatccttat gtgagacgta tggcatgatt tttgatggtc
    16561 atagtacgat tcgacacctt gaccaacaac agttggtctt ttttgacatt gactctatta
    16621 caggcttaga tcgaggggta caacaatgtc aaatgtacat ggctatgacg ttgatttgga
    16681 atcaggcatt gattcaagga agaagacaac gacgtttaat taaagaaaaa caaatggaag
    16741 aacaagactt caaatgcttc ttggcgatga ttgatgagtg ccataatgcg attaatccag
    16801 attttattga aacggtaaat tatgtcacaa actttcaacg agaaatgcgt aaagtagaag
    16861 caatgactgt tttagctaca caatccccac aagaaatggt gccagaaaat atgtcttctg
    16921 ataacttctc gaaactgaag aaagtctttg aattttcttc tacgaagatc tttatgcgta
    16981 tggatgaatc tattttacgt catatagaag gattagttgg taaatcaatg acaaactcag
    17041 aattagaatc cattcctcaa caaaatcaag gagacgctgt gatcaatttt ggctcaaaag
    17101 aaaccattcg tgttcatttt agtccgaaca aacgtcaatt aaaattgttt gatggaggaa
    17161 aataatggaa aaccaaaatg aaagtttaat caagcagtat gttaagcgtc gtgcaaagcg
    17221 acgcttattt ttgtggttgt ttggtacttc tgcaggtttg attactattt tgattactgt
    17281 gttcgtgacc ctttttctaa tacttgcggc ggattcgatt gataattctg attcagattc
    17341 aagtagtggt ggcgaagctt ttacaggaga atattcggaa ggcttaccga tttataaaga
    17401 aatcaaagga agaggccctt tttctgatga gattgcgcaa tatgctgtag gtgcagcagt
    17461 gaaatataaa ttattaccaa gtgtgatcct ttcgcaatac ggttatgaat cagcgtttgg
    17521 tacgtcggcg tccgcaagaa atgatctcaa ctattttggg attacttggt ttgatggttg
    17581 tctgtttcct aaaggaactg cgcgaggaat cggtggtatt gaaggtggct ggtacatgaa
    17641 gtttcccaac tcaaaagcag ccttctccta ttacggcttt atggtagcca cacaatccaa
    17701 ttttaatgca tgtgtaggaa ataaaagccc tggcgcaagc ttattgatct taggacgagg
    17761 tggttatgcc gctgcaggaa ttactgaaga tagtccgtat tatacaggtt gtatgtccat
    17821 tatcacttct aataaattaa ccgaatatga tgaattcgcc atcaaacatt ggggtgaagg
    17881 tggcaataac aacggcacga tcactggtga atggacgaat ccattccctg gcagcagttt
    17941 agataaaagt tccttcagtg gtggtcaatt atttggaaca aatccaggcg gtgaattccg
    18001 tccgaatggc ttccatgatg gattagactt tggttcagtc gatcatccag gaagtgaaat
    18061 tcacgcggtg catggaggaa aagtcgtgta cgttggcaat cctggtattt caggtttagg
    18121 tgcatgtgtg atcgtgatta attacgacgg tttgaatatg gtatatcaag aatttgcgaa
    18181 tagtacagga aattctcgtg tgaaggttgg cgatcaagtg aaagttggtc aagtaatcgg
    18241 gatacgagat acagcacact tgcatttagg tttcactcga atggattggc gtcaagcaca
    18301 aggacacgca ttcacagacg atggtacatg gattgatcca ttaccatctt tgaatagcag
    18361 caaaaaatag atcaggagaa aaaatatgga aaataaaact ttaaaaatcg tcttaacagc
    18421 tgcaattagc gttagtttaa tcggcaatat cgcgttgttt tggcagctga aagaagaaca
    18481 agagacaaat acctttaaaa ttgaagaagt ggctaaaaac gcgtctgaga agctcaaaaa
    18541 aaattcctct gaggcacagg cgaagatcga caagttaaat caaaccatca atgagaaaaa
    18601 ccaagaaatc gatcagctga agcaacaaga tggcacaaaa gcaaaagagg aagtaactga
    18661 agcacaaaga aagacggcag aagagttcgg tcaattggcc attgataaat cattaagtag
    18721 aaatgaatta acggaaaaac taaaagatgt cgcaacccaa gaagtgatcg acaaattaag
    18781 tcctgcagac gatgatcacc aacatgatga ttacggaagt tactccttta cattaggtga
    18841 cgtgcaaact tatgctcaaa caagcagtgt aaaagaggaa caaaattttg tcgtatttgt
    18901 tgattataca atcggcaatc cgcaattcaa agatgtcaaa ccacaaaaaa taaaaggtgg
    18961 attaactgtc actgaaaaac aagtagatgg tcaatggaaa gtcatagact ttagttattt
    19021 cactcgttag gaggaagaaa atgagtaaga aaaaaggaga aagacaacgt ttcaaaaaac
    19081 gaaaaagtta tcttcaatgg ctgggaatct ttatgattct cggctttttg attcttgcta
    19141 gtccgattta tacgaatcag aaggtagata taccagatga ggtaagcacg aacgcctttt
    19201 taaacacgaa agagctgaca atggtttcaa aagaaaaagg agcgaaccag caattagttt
    19261 ttgaatttgc gatcgatgat gaagatcaaa gcttgttaaa agaactggct aatcttaatt
    19321 atcgcgtaga agtaaagaca gctaaagggg attatcaagc aatacgagcc aaagtgatca
    19381 aggtgtctga tgattatttt gcagtgaagc taacgcatgt accagaagaa tatatcgcca
    19441 tgcgtttaac cattattcct gaaaaaattg atccaaaagt ggatatgcaa gaaccacaag
    19501 atctgattta ttacgtgcac gaagataagg ttaaagatca agtgaaagat gaagattatg
    19561 aacaacacgc gatcaattac aaagtgaaag gatacaagaa agaacaaaaa gcagctcaaa
    19621 aacaaatgga atctttccaa gcaaccattg atttgaatga agaattagtg aagaagctaa
    19681 aagatcaatt gccttatcaa gtcgcagatg atcaggaaaa tactgaaaac aagattaata
    19741 gctaccagca agaaattgaa acatcgaaaa cgcaactgaa agatcaagaa gagatcattc
    19801 aaaaacttca agaaaaaatt gatcgtatga caaaagaaaa gatttagaag gacaggtgga
    19861 gtgaaaaaat gaagcgaaca aacttggctg acaaagatac tttcgctgag cagaaagtat
    19921 tgattaaagc ctatctcaaa gttgtaaaag ctaaagaaat atgtcaagaa gtgcatttat
    19981 ctaacacaac aatatctgag ttgaagaatg gtagaaagag tttagatacc ttaaaattca
    20041 gatcatttga agctctatat gtagctgcta aaaaatattt tacagctgat aacaaataaa
    20101 aaacaggagt attttatgtg aaaaaagtat ataaaaaatg cttatgaatc agctatatca
    20161 ccttaaccat ttgttaatga gatgggagaa aacattaacc acgattctaa cgcaaacatc
    20221 aagcacataa aacatttaac actcctcctt tctggctgaa gatttcaacc aaacaggaag
    20281 acagcgtatc aattatagca tacacttttt cttaaattca tttttcatat gacaaaatat
    20341 ttccttctaa tcgacaaagt tagaaggatt ttttattgtc taaatacaca aataacctta
    20401 atttttaaag agcataagga aacgtgatat cactttctca cgaaaggtgt taggtaggct
    20461 gtgcctacca cgtttctaag aaagataaat gatatcaaaa ttttggattt gtgtgtagat
    20521 ttgtgggtag gatgaaagcg aatgtgggca gtaaaataag cgtttgtgtg tagcaaaatc
    20581 aaaaaatgtg tagggatatg tgtagctaca catatcccta cacataataa atttggagga
    20641 aaatatggac ttattaatta gaaatattga agaaaagtat attaataaaa ttgacaaacg
    20701 ttgtgaagaa cttacggtca agactggcaa aaaatggagt cgaaatcaat acctaaaagt
    20761 tttgatcgaa aatgattttg atcacgctct tctgaattat aaaaaagacc aatttgatcg
    20821 gttgttagaa aaatttgtgg atattcaaac ttataatacg aaaactttag aagaatatat
    20881 tgcaacaaat aatcaattaa ttggtttgtt aattgaataa taaaaatagt attgtgaatt
    20941 tataaaagga ggaaatcaat tttggcaaaa gcaacaagaa aacatgtata tctttacgat
    21001 atgcatatcg aagtacttga tgaaataatt tctactcatg aagatatatc taattatagt
    21061 gaagcagtca gacatttgtg tatgatgtat gatccaaaaa tcgaagaaaa aataaatcca
    21121 attcaaatta aattgaatgc aatgggaaaa gaaatttcta ttttaaccga aatggtttca
    21181 gagtttgcgg atcttcattt gaaagataca ggaatactaa ttggtacaaa ttcaactgtt
    21241 tatcaagaag cagaagaacg tgtggaagga aaaattaaat ccaatcaaac caaaaaatat
    21301 tcttctaagt taaagaaacc agtgaatgaa tctgttcata ccagagtaga tccatttgat
    21361 ccaacgaaga ttctaaaaag ataaaagtag aaggagaacg tgatgaataa atcgcctgca
    21421 gttattctta cttgtcaatt taccttgccc aataaaaaat ctttttcaac atacattgat
    21481 tatatgacaa gagaaaaagc actggaagaa atggaacgac gtacgcccga agaagaacag
    21541 gaactgcaac gaatcaagaa tgctttagag gatttttata ttcctgaagg agaaactttt
    21601 tcggaaagta agacggataa agaattcagt gaaacgtcga atgaagctca atcgttgatg
    21661 gaacatggaa tcaattttga caagttagag gaacaagatt ttaccaaata tctttcttat
    21721 atgacccgtc actatgcgtt agaacaaaag aaagaactga cgcaaaggga acaaaaagaa
    21781 taccaacggt tgaaccaagc aatgaaaaaa tatcaaacag agccacataa aaaagcttca
    21841 ggaaatcttc ctggagtttt ttctatggct tcagacgaag tgaaaggaag tgatctgaag
    21901 gagatcaaac aaatcttcca aagaggacaa caaaaaggct caatcattta tcaagatgtt
    21961 atctctcacg acaattcgta tcttgaaaaa atgggcttgt acgatcccaa aacagatacc
    22021 ttagatgaag aaggtttgaa agcagctgga agaaaaatga tggagacatt attcgagaaa
    22081 gaacaattga atgaaacagg ttactggatg gcaacgattc accgtaacac taagcatatc
    22141 catattcatt ttgcagttgt tgaaaaagaa aatacgcgta aaccgtatac tgagattgaa
    22201 aatggtgtga gttatatcgt accgaagggg aagagaagac aagcaacatt agacgcaatg
    22261 aaaaccaatt atgtacatga gttagaacgt ttctcttatg aaaaggatcg aatgatcggt
    22321 atggagaaac gaaatttatt gacacgaaaa agtgatttgc gtaacacctt aacaaaagta
    22381 gtaaaagaac cagcacgtta cgatcgacac gccatgaact tattaaatga agtatataaa
    22441 accctacctg aaaaacgttc ggaatggaat tatggagatg aaaatcgaac caagctttca
    22501 ccatttacaa ggggaaaact tgatgagtta accaaatatg ttttaacaaa agaacctgga
    22561 tatcaagaat atatacagat ttcaaaagca ttgaaagaag aagccaaaag cctttatggg
    22621 gaaagcaaaa gagaaacaaa gaatgcagaa aaaaacgccc tctttgattt aaaaaagcgc
    22681 acaggaaatg cgattttaac agaactgaag agacaggata gtcaaataaa accattaata
    22741 gaaagtgtca atcagatgca atctatttac aatgaacgat cctttcgaac actcaaacag
    22801 ttgccaacaa atgaatacaa gtatagttat caagaattcg taaagcgtag gaaacaattc
    22861 caacaaagag ttgtcacgca gcgaagcttg cgtcaattaa atcgaacaat taatgcacat
    22921 gaagaaaaat accacgcaag taaagcatat gaagagcaac agcgaagaat ccaaatggaa
    22981 caagaaagac aataggagga agagaaatga aacaatattt agatcaatgg aaagtcatag
    23041 aaggatcact aaaagaagaa cgaatcgaac aacttcctga ttgtttagaa aaagagcatt
    23101 tgtttcagat aagcgaaatg ttgagaaacg aacagtttga tccaaatcaa tttttagttg
    23161 ttgagtaccc agctactggt gtgtattgtt gtaatcatgt gaagggtgaa aaatatttta
    23221 ttattcaaga atacgaaggt aagttagcgc cttattatac tacttgggaa ataaatgaag
    23281 agggaatcaa taatttccca tgtgaaagca ttgaagagtc tatttctctc acggaatgtt
    23341 aaataaatag agacgtaaaa gagtcctgaa cgtgattgtc caggactctt tttcaatgaa
    23401 ttgttttccg ccaattcact gagtggtgcg attcaatttt attatatcaa aagaaagtga
    23461 gattccaaag tgaagggagg aagaagaaat gactcagaca acgattggtg ttgtggttga
    23521 aaaaagcagg gataatctcg tttttgtgac agaaattcaa acaggtagag cttttgtagt
    23581 cacagacaaa gctgcaaaag cgtatcaaaa tggcaatatt ttaacgttaa atctgactac
    23641 gaagatgttc gttgatgcag tagaaaatta tccatttgtt tagacaaacg atattttaca
    23701 aggaggaaac ggacatggca gaagaaaaag aaccactaga taatagtcgt ttgggaaagt
    23761 ccaaaagaaa attagtacgg ttgcaaaacg aattaaataa tcaatttcaa aagctatttg
    23821 atcaccaaaa attgacaaat gggcaaccaa tgaatgacaa acgaaatggt cgttcatggt
    23881 ttaaccagca agaaaaaata gaaaataaaa tacaaagttt gagagaagag atcaagcaac
    23941 aagaaaaaca ggtagaaaaa cttgaaagac aagaagagct aaaggaaatg ggttataaca
    24001 agtacggtgg cctggacatg acgatcgaaa atattccaag aatcaaagaa gaaatcgaac
    24061 gctttgaaaa aggtgaatcg actttttcag ctgccacgat ccgaaaatac caacgaaaat
    24121 tggaaacatt agaacagctg aaagaaaaat cagagaaagg aaaagaaaat cttcttcctg
    24181 aagtacaagc gatcattgac agcggacgag tgacgcaatg gaaaaagaat ccaactatct
    24241 attttctgaa aggctatcga aaagtcgctt tagaactcaa tgaaaacggg ggatttgagg
    24301 aatctaaaaa ataccaagcc acgtcggaag aagaaaaggc agctgttcgt gaattacttg
    24361 aagaagctac acctactgat tctgtgaagg agaaagaaac cgatcatttc tatcgagtag
    24421 aattcaacga aaatgatcca gcaaaagggt tgaaaagtta tggtggggag atcgtaacac
    24481 tagaattgat cgatcaactc aaaacactgg ataaccaata cgccgcagaa gcaggctatt
    24541 ataaattcta ttttgaagaa gtgaagaatg gagaagtagt cgatcagata cgaatggatc
    24601 taggggatgg cgtcaatagt aatcacccca tctatttaga gttagctaga ttgtgcgaac
    24661 aatcacctga aaaggaacaa gaacaaacag tcaaaaatga acctatttca aaagtacaaa
    24721 acgagattaa agagacaaaa acaaaacaaa agggttatca aaaacgaacg gcagaagaga
    24781 ttaagcaaga agtcaaatca ctttcccaac aggcgcttga tgcggtgaaa aagcatactc
    24841 attcacctga agacgtcaaa gaacttttga attttatgtc tcgttttcca gaacgatcct
    24901 ttagaaatca attattgatc gaggaacaat ttccaggcgc aacggcttgt ttaggtcgtg
    24961 ccgcgttgaa aaaagaagga atctatatca aaaaaggaga acaagggaac aagatctttg
    25021 tcagaaaaac ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaacagagg
    25081 ctacaccaga agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt
    25141 actacacgat tgaaaaagtg tttgatatca cacaaacaca attgaaacct gaagactatc
    25201 cgaaaatctt cccgaaccgc gtctttgatt ttcaattgga tcaaacaggg cagacagaac
    25261 ttcaagttgg gattcaagcg gtagccaaaa atattggaat tcaaattcga gatatgacag
    25321 aaagtgaagt ctatcaaaga gaattaggac aagcacgtgg ggcgtacgtt cgtaacgaat
    25381 ttactggcga agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcca
    25441 caagtattca cgaattagcc catgctagaa tgcacaaatt ttcagaatta gatactgcaa
    25501 caaaagaact acaggcagaa atgacctcct atattgtgtg caagcatttt gggatggaca
    25561 cctcggagaa agctattcct tatattgcga catggacgaa gaatagtcag acgttggatg
    25621 ataaggaagc tgcggaacgt gggaaaatca tgaatgatgt cagtcgtgtc gcaaatgaat
    25681 tcattcaaac catttctaat gaaatcaatc aatacagaga aagagaacca gagatccagc
    25741 cagcagaagt gaagcaggag cataaaaata ctgtagaaac ggcagaacaa aagaatattg
    25801 tgcccgttgg ctcactttgg atcgacaaga aagacgggaa agtcctggaa gaagacacgg
    25861 gccgaacgtt acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtga
    25921 ttttaaaagg aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg
    25981 cgctaggaaa tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa
    26041 atgaaatcta ttatgaacaa caattgtcac aaaaagaacg cgtataaaac aagcaagaaa
    26101 gactatctga aaaatggata gtcttttttc ttttgggagg tttgaaaatg acagagaaaa
    26161 aaatgagtct cattgatcga tgcaagcaaa tggatattgt ggattttgca cgaaacaatg
    26221 gtttagcggt ggccaataaa ggacgagact atcgcttaga agaccatgat tcatttgttt
    26281 ttgatcgaag aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg
    26341 aattagctaa actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag
    26401 cagccactga ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt
    26461 ttgagacaga aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa
    26521 ggaattatct gaaggaagaa cgaaaactgc ccgattggtt gattgattat gcagaaaaag
    26581 aaggattgat tgccgaacta aagccaaaac atgaacggca aaatttctta gttcgagacg
    26641 atcgtttgga tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag
    26701 gggcgagtta tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata
    26761 agcatataga taaaaattcg acagcgaatc atggctttaa cctaaagatt ggtgatccta
    26821 aacagttaaa attttttgag agtagtattg atttacttag ctacgctgca ctgaatcgtg
    26881 atcagttaaa cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc
    26941 attattttgg tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg
    27001 agatttgtgt ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg
    27061 gcgcagttga tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt
    27121 ggcaagtgcc aagagaatac aaagtcattt atgaagaagt cgcaaaagaa gaaaaggtca
    27181 caccagaagc tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac
    27241 tggtttccgc tcacaaagtc aatgcgtctt ttggtcagca gctttctgtt aacgattcaa
    27301 tagaagtcat tagtttgaaa gatatttgta gagaagtcgc aaaagaatta aaagattgtg
    27361 aacgctcgaa tggtacgtat gattttgatc gtttttatca aggaaaaggg gatattaatt
    27421 ctcagattct tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac
    27481 atgaatttgt acctgaagtg aaaaaggatt ggaacgatca attgaagcat gagatccatc
    27541 aacaggaaat tagaaagcaa aaacgtgcga tgttgtttca acaaggcaga caacaagaaa
    27601 gggagtgaga tcgtcacgat gaaaactgtc attttagcag aaaaaccgtc acaagcgaag
    27661 gcctatgccg atagcttttc taaagccacc cgaaaagacg ggtattttga aatccaagat
    27721 cgattgtttt cgggtgaaac tgtgatcacg tatggttttg gtcatttagt cgagttagat
    27781 tcgcccgata tgtacgatga aaattggaaa caatggtcat tagagcattt gcctattttc
    27841 cctacacatt atcactatca tgttcctaaa gataagaaaa agcaattcaa cgtggtgaaa
    27901 cagcaacttc aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa
    27961 ctgatcgctt ggacgatcat tcaacaagca ggcgctgatc aaggaaaaac ctttaaaaga
    28021 ctttggatca actccttaga aaaagaagcc atttatcagg gattccagca attacgagac
    28081 gcagaagaga cctatcccaa atttgaagaa gcacaagcac gccagatcgc tgattggttg
    28141 atcggcatga acggcagccc actgtatagt ttactcttgc agcaaaaggg cataccagga
    28201 agtttttcct taggcagagt ccaaacccca acgctttaca tgatttatca gctgcaggaa
    28261 aagattagaa acttccaaaa agagccttat tttgaaggga aagcccaagt aaccgctcaa
    28321 aatggcatat ttgatgcgaa gcttgatccc aatgaaaccc aagcgacgca agaagcattt
    28381 gaagcctatt taaaagaaaa aggtgttcaa gtaggaaagc agccaggcac gattcttgaa
    28441 gtcgaaaccg agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag
    28501 tctaaaatga atcagctcat gaaagctagt gccaaagata ctttggaagc catgcaaggg
    28561 ttgtatgaag ggaaatatct aagctatcca cgaacagaca ccccttatat tacagaagga
    28621 gagcatgcgt atctgttgga tcatttagat gaatacaagc attttttaaa ggctgaatca
    28681 ttccctactc ctattcatac accgaatagt cggtatgtga ataataagaa agtccaggaa
    28741 cattacgcga tcattcctac aaaaacagtt atgacagaag caacgtatga aaagctgaca
    28801 cctttacaac aagcgattta tgatcaagtt ttaaagacga cggtggccat gtttgcggaa
    28861 aaatatacct atgaagaaac tacgattttg acacaagtcc agcagcttca gctaaaggca
    28921 gtcggaaaag taccagtaga tctaggttgg aaaaagctat ttggcaaaga gagcgacaga
    28981 aaagagaagg aagaagaacc gctacttcct aaagtaacaa aaggagaaac ggtgacggta
    29041 gatctacaaa tctttgaaaa agaaaccaag ccaccacaac cttacacgga aggtacacta
    29101 atcaccgcca tgaagacagc tggtaaaacc gtggatagtg aagaagcaca atccatattg
    29161 aaagaagtgg agggaattgg tacagaagcg acacgagcaa atattattga aaccttgaag
    29221 caaaaggaat atatcaaggt agagaaaaat aaacttgtgg tgacgaataa aggaattttg
    29281 ctttgtcagg ctgttgaaaa agaaccgctg ttaacaagtg ccgaaatgac cgccaaatgg
    29341 gaaagctatc ttacaaagat tggtgagcaa aaagggacac aagctacttt tctagcaaat
    29401 atccaaaaat ttgtttccca cttgttggaa gtcgtcccag gacaaatcca agccactgat
    29461 tttggagcaa cgttacaaga ggtgaaagta gccagtgaaa agcaagaagc ggcgcgtcat
    29521 ttaggatctt gtccaaagtg ccaggaaaaa gaagtcatac tttatcagaa ggtggcgact
    29581 tgcacgtctg aagcctgtga ttttaaattg tgggtaacga ttgccaaaaa gaaactcaca
    29641 gcgacacaac tgaaagagat cattcagaac ggccgaacaa gtcaaccagt cagaggacta
    29701 aaaggtcaga aaggttcgtt tgaagcaacg atcgttttaa aagaagactt tacaacagga
    29761 tttgagtttt ctgaaaagaa gaagaccacc tacaaaagaa aagtgagacg taaaacgagt
    29821 tagaattgac ggagggaaaa acgatgagaa atacaacgca taaagaacaa gaaatcgaaa
    29881 atcaaaaagc caaaatacgt tcagagcagg agaaaatgcg tgccagcaaa cgaagactac
    29941 agcaattgaa gaatcaacaa cggattcaaa aagaacttga attagatcga taaatcctcc
    30001 tgttgttaat attaaactaa catgttatag ttatgttagt ttaatattaa cattcgagag
    30061 ggaaagcgat gaaagataaa gtcaagtgca tttttgagaa atacaatggt aatctatcct
    30121 tgaaggatgc tagaaatgaa gggttatcac ctatgacgtt agatcgttta gccgaaaagg
    30181 acaaaataga aaaaatagca tcaggttttt ataccttaaa agatagtttt gtggatgaat
    30241 tatatctcgc tcaaagtatc tatactagag gaatcttctc tcacgagaca gcgcttgatc
    30301 tttttcaagt aggaacatat atccctaaaa aaattaatat gatgtttcct aaaggataca
    30361 atgtttcgaa agagaattta gatcagtatg ccattcaacc gcattacacg aataaagaaa
    30421 actttgaact gggaatcaca gaggcagaaa gcttttacgg caataaaatt ttcgtctatg
    30481 atttagagcg aacgttatgt gatatgtgga atcccagata taaagcaagc gtagaagtaa
    30541 aacaagaagc attaaaagaa tatatgacaa gtaccagcag aaatacaaat aagctaagaa
    30601 gatacatgaa tattttaaaa tcaccaaaag aaatgacttt gtatatgttg ccactttatt
    30661 gagaggagta aaggtgaatg acaccgacac aatttaaagc gaaaacaaga aatgttgcag
    30721 ctgagaaaca tttaaaccca caaattgttc aaagatatta tatgatggaa aaattattag
    30781 aatgtattgt tgaatcgcct tatcatgatg attttgtatt aaaaggggga tttctgatcg
    30841 gatcaaaata cgggttagaa aaccgttcaa ccgttgatat tgatacgact tatcgaaatt
    30901 cgaaactaac aaaagaaaaa ttagaaactg ttttttctga attaacagct gctcctacaa
    30961 aagatggcat tcggtttgaa ttaaagggct taacagagac gagggaagcc gattattacc
    31021 caggttttca agcaaagttt attgcttttc ttgaaaatgc acgtgtacct tttaaattag
    31081 atattacttc aggtgattct attattccag cagcattgat atatgaacat aaattgatgt
    31141 ttgaagataa aacaattcat attccagctt atcctacgga acaaatttta gctgaaaaat
    31201 tacatgccac gtttagtttc ggaatagata attcacgtat gaaagatttc tatgatctgt
    31261 atatgatccc taaactagaa cgtatcgatg agataaattt gtataagagt gttcaaggaa
    31321 catttaagga aagaaataat caatcagtgt ttaagaattt gtataatcag gaaatgcctc
    31381 aattgatgaa gaatgaggga ttgagggaga aatggaaaag atatcagcaa gaaaactatt
    31441 ttgccaaaga tatttctttc gaatctacct taacttctgt tgattcgctg atgcaatcaa
    31501 ttgtcgagca agaggaagta gaacgaaaac aaaattttaa gagatcacaa caaatgaatc
    31561 aagaaatgga gagataaaga tgatcaataa tgtaacttta gtaggtcgat taaccaaaga
    31621 tcccgattta cgttacaccg caagtggcac tgcagtgacc acttttacct tagccgttaa
    31681 ccgtaatttt actaatcaaa gtggcaatcg agaagctgac tttatcaatt gtgtgatttg
    31741 gcgcaaacca gctgaaacga tagcgacatt agctaaaaaa ggcagcttga tcggcgtcgt
    31801 cggacggatt caaacgcgga cttatgacaa ccagcaagga cagcgtgtct atgtgactga
    31861 agttgtggcc gataatttcc aactattaga aagtaaagca gcgacagaaa gccgtatgca
    31921 cgctgatcaa tcgtccagca gtccaagccc taccaccttt gaacaacggg atacagcgac
    31981 gcctaacaac aatggattga acgcttcaca gaatccattt ggtggacaat caatcgatat
    32041 tagcgatgat gatctaccgt tctaagtagc attttctatt ggttgcattt gctacggttt
    32101 atgttataat ttagacaaca aaaagaattt tcaatctata accaaaaacc actagctggc
    32161 gggctagtgg ctttctttta cgtttctatt ataagaatta acgggtaggc ttactgtctt
    32221 tcttggcaaa tttacaatca agccatttgc agatatagtg cgcggctact tctgccatga
    32281 ttgcaaaaac aaaatcaaaa agaattttca aacctataac ctcctcccct tgccagatta
    32341 ggccggggta gcagacagca agactattat agcataattg aaatatccaa atgattggat
    32401 ttttgctata attttagcga ggtgattgtg atgaacaaat atgttggttt gcttgataaa
    32461 atccgagtaa taaaaacgca accgttattg gttcgcttta ctttacaaac gattcatgaa
    32521 tcgattaatt gtgtagttgc agatattgaa attatcgata aattgctaat tatggatgat
    32581 ggaaaataca atattgccgt cacaggtcac ttcaataaac gaaatcagct agttattgct
    32641 agcatgtatg ttagaaatcc cgatcatttt acgcgatcga tgggcatata aataaaagaa
    32701 gagttgtagt cctaaatgag gattgcagct ctttttgttt tacatagaaa caggaaaaga
    32761 cctttttagg aagacacaag tgccttctca attgaaaaac ctttctctca ctccaaccgc
    32821 caccgccgtt cgagaagaaa ggaagtgaac gctgcacgtt cactaagata tggtgtcttg
    32881 caaagcaaga caaaatagac aaaacttcct ctcaccaaaa ggttcgttcc tgttcgttat
    32941 ctctttattg atttgccaga ccggcaacaa gttgcctttt atcaccaaaa agcgacaagg
    33001 acaagggtaa atggcacgct gcgcgccctt gtccttgtcg cttttcgttg atttattctg
    33061 gccaacaaat caataaagaa agaactaacg aaaggaagta aaacctttcc taagaggagg
    33121 cagaatcaaa catgcgaaag aaatttgatt attggggtgt tcccttcagc gaattattcc
    33181 caaactatca tgcaccacat actgttgaat gcgattgtgg agaaagagcg aaatgtatca
    33241 aaagctatcg tttgtatcaa tgtccaacat gcgggaaaaa atataccttg tcttatggcg
    33301 attacatttt gattgatgag aaaggaaaga aacgctgatg aaaacacaac acaaattatt
    33361 gactgtaaaa gaagtcgttc aaattttggt ggacaaagaa gtcatttctg aaaaagtagc
    33421 agaagcttta cttattccgc
//
LOCUS       DAFKHN010000029        33009 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFKHN010000029 DAFKHN010000000
VERSION     DAFKHN010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.029"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..223)
                     /locus_tag="LY912_001309"
     CDS             complement(<1..223)
                     /locus_tag="LY912_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955018.1"
                     /translation="MNLTRDLIFLVIYILGMSGILYWRKRQSDPALFFYCGTWTFMMM
                     VTYFVVLEVFYHTFYFLIPLLFFSIFAFFY"
     gene            750..1475
                     /locus_tag="LY912_001310"
     CDS             750..1475
                     /locus_tag="LY912_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBM6955019.1"
                     /translation="MNKKRFKRIERKFALTYDQAKYLKTLFPKQVVRDKYSDHFISSL
                     YFDTNDHHFLKEITTEKSYREKFRIRKYGDPQDISPIYLEIKRKFQGMTDKRRIKLAH
                     HELDDMLENIELAETTFSNLEEEYIFNEIQWLFRRLALEPKVYIYYLREAFVNRDSED
                     LRITFDQNIHYRLMNLTTWEHCTEDNLVAPEIDVLMEVKTTGEIPEWLQVGLDRMGKK
                     EIKFSKYKQVYKRYIQEDPLYVQ"
     gene            1465..2139
                     /locus_tag="LY912_001311"
     CDS             1465..2139
                     /locus_tag="LY912_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBM6955020.1"
                     /translation="MFNSVLKNEPSQLTLDDFFLCMVVSILLGILIAYTHMYQNNCTK
                     NFMFALIGLPTLVHTVILLINGNLGTGIAVLGAFNLVRFRSAQGNSRDIFSIFWATSI
                     GLATGTGYIVYALFVSSIVAAIQVIIFTLPIKNKHTVFNTEKTIKLKVSKSLFLSSII
                     EEKIAEYTENCNLKKVKINKETCSLHYIVKVKTSMLEKELVRTIMDHPEVISITVGMD
                     KSNKLL"
     gene            complement(2427..2711)
                     /locus_tag="LY912_001312"
     CDS             complement(2427..2711)
                     /locus_tag="LY912_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 family protein"
                     /protein_id="HBM6955021.1"
                     /translation="MRQKCFLLLSHSQKVKPIFWLSIWDGFFKVSFHFPEKTREKLVT
                     LSLSEGTKEKIKTLQANGNKRKHLSVIFDVDHLEQLADIYQLAEFKKQNG"
     gene            complement(3005..4312)
                     /locus_tag="LY912_001313"
     CDS             complement(3005..4312)
                     /locus_tag="LY912_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBM6955022.1"
                     /translation="MFKKNTRFIVLLASLILCITSFLPSATVQADDAFKINAKAAFAV
                     DAESGKILYDQDGEKTMGIASITKIIGLYIVLEQIKEGKLSWEDKVAISDYAEKLSVV
                     PDLSNVPLHKENDYTVKELVDSAFIQSANASMVALAEKVAGSESKFLELMKKQLKDWG
                     IKDATIVNASGLNNSYLGENRPENTGETDENQLSAKDVAIVARHLILDYPEVLKITST
                     TNQTFGENTQSPVEMVNWNWMLPGFVNYHEGVDGLKTGTTDFAGACFVGTINKDGRRI
                     ITVVLNADNHEENPSARFNETSRLMDYCYDNWSEKELGKANASIPSLKDIKVKDGKET
                     SVNVALKSPVKVWVENGMDTGKLTITPTIDKKKVTDDQVTAPINKGTTVGSATIQLAD
                     DKLGYLEANQEPSTDIITTSTVEKANIFVIGWRHVTDFFSNLF"
     gene            4801..5907
                     /locus_tag="LY912_001314"
     CDS             4801..5907
                     /locus_tag="LY912_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955023.1"
                     /translation="MAKKEKELLSQLTSEGTKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKITSLLDDPSFWRSATTSVAVIVSPEQVFIHRLGI
                     PVDDQYYVSDLPYLLAIIKNGHFNYSYYLLGLNRDSMKLYEVTNKQVKEVALPEDAPR
                     DVVTALGSELTGGGLNYASNGSEGTTFHGVNPKDEEVEIDWVNYYQAVDDYLKDTFEN
                     PEKWPIFLFALPENQTMFKKVAKNPYYRSDVAISASPAQLSLKEIEAGAKKLSQELAV
                     KEASDYNKLLDKKFIDQLVDIIPAAKEGKISHLFIATSNLADGFGEDPETEYDRRQVL
                     NELADNVITNGGQVFILEQKDAPDEKSLVAILRY"
     gene            6498..6698
                     /locus_tag="LY912_001315"
     CDS             6498..6698
                     /locus_tag="LY912_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBM6955024.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            6845..9634
                     /locus_tag="LY912_001316"
     CDS             6845..9634
                     /locus_tag="LY912_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBM6955025.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIEAGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSSHTGMDTSRFIYHVLEEMKENPEPLDLSLEIIDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIMEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPGQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHAFFADVAHRGTGFLARNQSFYKQDFVRFLQKKIKQSNFLIVNHAFLVQETQRKEP
                     LLPASPYLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICVAEGLMNLVSSKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAMDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLLDFQAAMLPSTVWYPRYDHILYIGGTLKIGP
                     NRQYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLEAALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAIDEI
                     YQDIHEFLKKNEEGS"
     gene            9681..10208
                     /locus_tag="LY912_001317"
     CDS             9681..10208
                     /locus_tag="LY912_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBM6955026.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            10229..11419
                     /locus_tag="LY912_001318"
     CDS             10229..11419
                     /locus_tag="LY912_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBM6955027.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            11459..12757
                     /gene="asnS"
                     /locus_tag="LY912_001319"
     CDS             11459..12757
                     /gene="asnS"
                     /locus_tag="LY912_001319"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBM6955028.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            13691..14365
                     /locus_tag="LY912_001320"
     CDS             13691..14365
                     /locus_tag="LY912_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBM6955029.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWREDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQKAGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            14362..14703
                     /locus_tag="LY912_001321"
     CDS             14362..14703
                     /locus_tag="LY912_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955030.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVGQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            14733..15092
                     /locus_tag="LY912_001322"
     CDS             14733..15092
                     /locus_tag="LY912_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBM6955031.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     AFLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            15616..17697
                     /gene="cadA"
                     /locus_tag="LY912_001323"
     CDS             15616..17697
                     /gene="cadA"
                     /locus_tag="LY912_001323"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBM6955032.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNELIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            18008..19474
                     /locus_tag="LY912_001324"
     CDS             18008..19474
                     /locus_tag="LY912_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6955033.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            19784..20257
                     /locus_tag="LY912_001325"
     CDS             19784..20257
                     /locus_tag="LY912_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
                     /protein_id="HBM6955034.1"
                     /translation="MGRENRPSQGRSKKSPAFRIQAKKWFLQEQQSFIVSNPSWIVEG
                     NYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLKRKINKKSRPDMPESFSEKLNRK
                     YLEFLSFIWHFEGNNEPKIQQLIQVANARNKLIILKTRREKQEFLTKLKIESKNN"
     gene            20331..20771
                     /locus_tag="LY912_001326"
     CDS             20331..20771
                     /locus_tag="LY912_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBM6955035.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQKGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            20784..20993
                     /gene="copZ"
                     /locus_tag="LY912_001327"
     CDS             20784..20993
                     /gene="copZ"
                     /locus_tag="LY912_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBM6955036.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            20993..23179
                     /locus_tag="LY912_001328"
     CDS             20993..23179
                     /locus_tag="LY912_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBM6955037.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            23199..25370
                     /gene="copB"
                     /locus_tag="LY912_001329"
     CDS             23199..25370
                     /gene="copB"
                     /locus_tag="LY912_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBM6955038.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(25482..27653)
                     /locus_tag="LY912_001330"
                     /pseudo
     CDS             complement(25482..27653)
                     /locus_tag="LY912_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(27643..28584)
                     /locus_tag="LY912_001331"
     CDS             complement(27643..28584)
                     /locus_tag="LY912_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBM6955039.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            complement(28729..29577)
                     /locus_tag="LY912_001332"
     CDS             complement(28729..29577)
                     /locus_tag="LY912_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBM6955040.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            29931..31220
                     /locus_tag="LY912_001333"
     CDS             29931..31220
                     /locus_tag="LY912_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955041.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            31294..31863
                     /locus_tag="LY912_001334"
     CDS             31294..31863
                     /locus_tag="LY912_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBM6955042.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(32039..32305)
                     /locus_tag="LY912_001335"
     CDS             complement(32039..32305)
                     /locus_tag="LY912_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBM6955043.1"
                     /translation="MHRTFGSRGCPTLHLADRYAERKTPTLCFAFSARTRQAGIPLED
                     IKDFLGHKDVSTTQVYAHISPEVKKRSMNQLENYIEEQIKKHSN"
     gene            32300..32992
                     /locus_tag="LY912_001336"
     CDS             32300..32992
                     /locus_tag="LY912_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBM6955044.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
BASE COUNT        10972 a         5756 c         6844 g         9437 t
ORIGIN      
        1 aatagaaaaa tgcaaaaata ctgaaaaata gcaatggaat caaaaaataa aatgtatgat
       61 aaaaaacttc taaaacgacg aagtaagtga ccatcatcat aaaagtccac gtcccacaat
      121 aaaagaatag agcgggatcg ctttggcgct tgcgccaata gaggatgcct gacattccta
      181 aaatatagat aactaaaaat atcaggtctc tagtaagatt cattgaatga actcctttcg
      241 atttgtaaat tttttcttaa aaaagatagc atcatttagt agtaaatata tcgaatatag
      301 aaaagttagt tactaaatag tcaatcagtt ttttcacgac gtttctatta taacgaatta
      361 tgttgaaaaa agcttttatc gaaaacataa atcttcaaat taacagattt tttagacctc
      421 gatcatgatg aagaattttg tagatacaaa taactgtaac attgaaaatg aatgcgaaaa
      481 cgatattttt ttttattgga aaatatcggt caagcaataa accagttgca taataaaatg
      541 ttaacggcaa caaaatctgt ggaaggaatg aaccggatga tttgatggaa aaaacaagat
      601 agacaagaag tatacatagt aaaacgtgga acaagtaggc cagaatgaaa aatcagtttt
      661 tatccactcg cttttctata cattcactgt cacaaatata atcgaaagta attctatttt
      721 gagataaagt attttatagg agatagtata tgaacaaaaa aagatttaaa cgtattgaaa
      781 gaaaatttgc attaacttat gaccaagcta agtatttgaa aacactattt ccaaaacagg
      841 tagttcggga taaatatagt gatcatttta tttcttcctt gtattttgat acaaacgatc
      901 atcacttttt aaaagaaatc actacagaaa agtcctatcg agaaaaattt agaatcagaa
      961 aatatggaga tcctcaggac atatcgccta tctacttaga gataaaaaga aagtttcaag
     1021 gaatgacaga taaacgtaga ataaaattag cgcatcatga gctcgatgat atgttggaaa
     1081 atatcgaatt ggcagaaacc acattcagta atttagaaga agagtatatt tttaatgaaa
     1141 tacagtggtt gttcagaagg ttggcattgg agcccaaagt atatatctat tatttaagag
     1201 aagcatttgt aaatagagat tcagaagatt tgcgaatcac ttttgatcaa aatatccatt
     1261 accgtctaat gaacttaacg acctgggaac actgtacaga agacaatctg gtagcgccag
     1321 aaatcgatgt gctgatggaa gtaaaaacga caggagaaat acctgaatgg ttacaggtag
     1381 gattggatag gatgggtaaa aaagagataa aattttctaa atataaacaa gtctataaaa
     1441 gatatatcca agaggacccg ctctatgttc aatagtgtct taaaaaatga gccttctcaa
     1501 ctcacactag atgatttctt tttatgtatg gtggtgtcga ttttgctagg cattctgatt
     1561 gcttacaccc atatgtatca aaacaactgt acaaaaaact tcatgtttgc cttgattggg
     1621 ttacctactt tagtacatac cgtcattttg ttgatcaacg gtaacttagg cacggggatc
     1681 gctgttctag gcgcatttaa cttagtgcga tttcggtctg ctcaagggaa ttcaagagat
     1741 attttcagta ttttttgggc aacgtcgatt ggtttagcca cagggacggg atatattgtc
     1801 tatgcactat tcgtgtctag tatagttgct gctatccaag tcatcatctt cacgcttcca
     1861 atcaaaaata aacatacagt ttttaatact gaaaaaacga tcaagctaaa agtttctaaa
     1921 tccttgtttc tttcgagtat tattgaagaa aaaattgcag aatatacaga aaactgcaat
     1981 ttaaaaaaag taaaaatcaa taaagaaact tgttccttac actatatagt aaaagtaaaa
     2041 acgagtatgc ttgaaaaaga attggttcga acgatcatgg atcatccaga agtcatttcg
     2101 atcactgtag gtatggataa atcgaataaa ttattgtgat aaccaagaaa gtacttaaca
     2161 atgaagtaag accccagttc caaagtttag cggggacact tcaataaagt actttctttt
     2221 ttgtcttcag caactactgg taaaactgag agcaagcttt cgtgagagta cagcgataaa
     2281 gatcaacctc cctttttatc tcgagcaatt tccttgcaag gctgtttcgt tgatcttaaa
     2341 cgagttagca acagtcaaag atgcgatggc cataaaaaaa ttgcattaag ttggctggta
     2401 tctgatagct gggaatctaa ggaagactat ccattctgtt tcttaaattc cgctagttga
     2461 tagatatcag ccaattgttc cagatgatca acatcaaaga taaccgaaag atgtttcctt
     2521 ttattcccat ttgcttgaag agtttttatc ttctctttgg ttccttcact caatgagagt
     2581 gtgactaatt tctccctcgt tttttctggg aaatgaaagg atactttgaa aaatccgtcc
     2641 caaatagaaa gccagaagat cggttttact ttctgagagt gggacaaaag taagaaacac
     2701 ttttgtctca ttctttaaaa acgaataaac ggtgggagca gaagcaactc cttcggaaat
     2761 aagccaaaat tcacaaaaat ttgaaaagca attttcgtga atttcttctt atttctcgga
     2821 gttaaacact tctgtcccaa cctcttgtat tcaccttttg atagccaagc ttttccatca
     2881 ttataaaacc gcaaatttca aaaaaaaacg aacaatacaa aaagcgtatt gctcgttttt
     2941 ctcttcagtt tctcacacct aaacgacttt tgtctcgacc tctttttggt gactattcat
     3001 gatgttaaaa taaattactg aaaaaatctg tgacatggcg ccaaccaatg acaaaaatat
     3061 tagctttttc aacagtagaa gtggtaatga tgtctgtcga aggctcttgg tttgcttcca
     3121 aatagcctaa tttgtcatca gctaattgga tcgttgctga gccaactgta gtgcctttgt
     3181 tgataggagc ggtcacttgg tcatccgtta ctttcttttt atcaattgtt ggagtaatcg
     3241 ttaattttcc agtatccatt ccattttcga cccagacttt tacagggctt tttagcgcaa
     3301 cattgacgga ggtttctttt ccatctttca ctttgatgtc ttttaggctt gggatgcttg
     3361 catttgcttt tccaagttct ttttctgacc agttgtcata acaataatcc atcaatcgtg
     3421 atgtttcatt gaatcgggca cttggatttt cttcatggtt atctgcattt aaaacgactg
     3481 tgatgattcg tcggccatct ttgttgatcg ttccgacaaa gcatgcaccc gcaaaatcag
     3541 ttgtgccagt ttttaatcca tcgacacctt cgtgatagtt tacaaaacca ggtagcatcc
     3601 agttccaatt gaccatttca accggtgact gtgtgttttc gccgaatgtt tgatttgtgg
     3661 tactcgtgat ttttaagact tcaggataat ctaagatgag gtgacgagca acaatagcga
     3721 catctttcgc agacagttga ttttcatctg tttcaccagt attctcaggt cgattctcac
     3781 ctaggtaaga attgtttaaa cctgatgcat tgacgatcgt tgcatctttg ataccccaat
     3841 cttttagttg tttcttcatt agctcaagaa atttactttc actgcctgca actttttcag
     3901 ctaaagcaac catggaagca ttggctgatt ggatgaaagc tgagtcaaca agttctttca
     3961 ctgtataatc attttcttta tgcaaaggaa cattcgatag atccggcacg acacttaatt
     4021 tttctgcata atccgaaatg gctaccttat cttcccaaga taatttaccc tctttgattt
     4081 gttcaagtac gatatataga ccaatgatct ttgtgatgga agcaattccc atcgtttttt
     4141 cgccatcctg atcataaagg atttttccac tttctgcatc tacggcaaag gcagctttgg
     4201 catttatttt aaatgcgtcg tctgcttgaa cagttgcgct aggcaagaaa gaagtgatac
     4261 ataagataag acttgctaat agtacaataa aacgggtatt ttttttgaac atctttgttc
     4321 tcctcatttt taaattgatt cttacaactt agaatattat cagagagaac aaaaggtttc
     4381 aatggttctg aaaaaaacct tataaagaac aagtcttatt aatgaagaat catagaaagt
     4441 tatcttttgg gttcattgac acgaactttg actggctgaa cttcgggttc ggttaggcgt
     4501 gatgctgcaa aaagggcgcc tgctgagagt gcgaccaaac taaaaatcat gaataattgc
     4561 ataagatcac ctcgttcttt tttgtttttt tatagtatag caagagagtt tgaagctact
     4621 gttaaggaaa tgagcatata attgatgaaa gtatgaaaaa aatatgaagt aggacaacac
     4681 aactaaaaat cgatcaggta tttctctggt agggattcgt tttattgtat tgataaaatg
     4741 ggatgtggta gactttattt acagatacaa agaaatgatt tttttaggag gggtacgttt
     4801 atggcaaaaa aagaaaaaga attattatca caattgactt cagaaggtac caaaggaccg
     4861 tttgtcacga ttatgttaaa cacccatgtt gcgcatcaag acgtagaaaa agatcaaatc
     4921 aaattcaaga attttgcaaa ggaagcgaaa aagcgctttg aaaagaaata ctctgagcat
     4981 gattggtctc cattccaaga aaaaattact agtttgttgg acgatccgtc tttctggcgt
     5041 agtgccacaa cgagtgtagc tgtcatagta tcaccagaac aagtgtttat ccaccgtttg
     5101 ggtattcctg tagatgacca gtattatgtg agtgatctac cttatttatt agcgatcatc
     5161 aaaaatggac atttcaacta ttcatactat ttattaggat tgaatcgtga ttcgatgaaa
     5221 ttgtacgaag taacgaataa acaagtcaaa gaagtggctt tgcctgaaga tgcaccaaga
     5281 gatgtcgtca ctgctttagg atctgaacta acaggaggcg ggttgaacta cgcatcaaat
     5341 ggtagtgaag gtacgacgtt ccatggagtc aatcctaaag atgaagaagt cgaaattgat
     5401 tgggtcaatt attatcaagc agtcgatgac tatttgaaag atacatttga aaatccagag
     5461 aaatggccta tcttcttatt tgcattacca gaaaatcaga cgatgttcaa aaaagtggcg
     5521 aagaaccctt attatcgttc cgatgttgcg atctcagctt cacctgcaca actttcatta
     5581 aaagaaattg aagcaggcgc aaaaaaacta tcgcaagaat tagctgtcaa agaagcaagt
     5641 gactacaata agttgcttga taaaaagttc attgatcaac tcgttgatat tataccggca
     5701 gcaaaagaag ggaaaatatc ccatttattc attgctacat ctaatttagc agatggtttt
     5761 ggcgaagatc cagaaacaga atatgaccgc cgtcaggtgc tgaatgaact agcagataat
     5821 gtgatcacga acggtggtca ggtctttatc cttgaacaaa aagatgcacc agacgaaaag
     5881 agtttagttg cgatcttacg ttattgagtg aaaactacca aagtagatga atggtcaggc
     5941 gttgatagaa gtgtatagct ccgagagaag gagtttcctc tgtttcagcc gttggattca
     6001 tcttgagcga gagacaaaag ctagcttttg tctctcgctc attatttttg tgctttagtc
     6061 ccattggctt tgcgagggga agatactttt ctcaaaaaaa cgaaccttgc agttgagagg
     6121 gggatagatg cgcatactaa tttttatcag ttaaaaaatg atgtggatca ttagagaatt
     6181 ccaaagttcg ttcatccttt ttcagataat aaattgaaat tttttgcaaa agtgaaaata
     6241 gcaaatagaa attttctgaa tcttataggg gtgatttcga gaaaacgttc gtttatttgc
     6301 aaatatatct tctaaataag agaataaata caaaaaaata aggaaaaact ctggcaattt
     6361 tgtaaacggt atgatatagt aagaatgtag tttttgttcg gtaatctgtg gtagcttgtt
     6421 tcaaataaac atcttccaga tatacaccat tcaagtaatt gcaaaatatg tgttgataca
     6481 caaggaggat ttttattatg gaaacaggta cagtaaaatg gtttaactca gaaaaaggat
     6541 ttggattcat cactgcagaa aacggaaacg atgtattcgt tcatttctca gctatccaag
     6601 gcgacggatt caaaacttta gaagaaggcc aagcagtaac tttcgacgtt gaagaaggtc
     6661 aacgcggacc tcaagcaaca aacgttacta aagcttaatt tacctatatt aaaaataaaa
     6721 gtccagacat ttatgtgtct gggctttttt gtcttttttt ccttaaaaag cgatgagagt
     6781 atttttctgc actttgtagt ataatttcaa aagaacatta gaggcaggag aagaggaaga
     6841 tattttgaaa ccaagaactt atgcagtcgt tgatatcgag acgactggga cgaatccaaa
     6901 agaagatcgg atcatccaat ttggctgcgt catgattgaa gctggtcgga tcacttcacg
     6961 tttttcgatc gatattcatc cagggcggaa gatttcaaaa caaatccagc atttaacagg
     7021 gatcacgaat caacgcgtcc aaaaagcgcc ttattttgaa gatgtcgccc aaacgattta
     7081 caatcttttg gcagacacca tatttgtcgc gcataatatt tattttgatt ataatttttt
     7141 gaaccatgaa ctcatgcgat gcggacttcc tagtttgaag ataccgggca tcgataccgt
     7201 agaacttgca caaattttct tgccgacgga accaagtttt cgcttagctg atttgtcaga
     7261 aagccttggc tttattcatg agaatcctca tcaggcggat agtgatgccg aagtgacagg
     7321 tcagcttctt ttactgatcg aagaacgaat gaggaaattg ccgatcatca cattagagca
     7381 gattgcacga ttaagtagcc atacaggaat ggatacgagt cgtttcattt accacgtgct
     7441 tgaagaaatg aaagaaaacc cggagcccct tgatctctca ttagaaatca tcgatgggct
     7501 agctttgcag aaaaaagaag tggagctatt cacatccgtc cattatggcg agcggacata
     7561 tccaagaaaa aaacaagcaa aagaaaaaat gtttggtaaa acactgatgt atcgaaaaga
     7621 acagaacagg ctgatgaatg ctgtctacga ccatttcaca aaagatgaat caaaagattt
     7681 gatgatcgaa gcagctacag gaatgggcaa aacgattggt tatctgttgc ctttgagtta
     7741 tttggctaca cctgaaaaac cagctgtcat cagcaccgtt tcgcttgttt tgcagcagca
     7801 gatcatggaa aaagacattc cattactgaa tcaattgcta gatcagccga tacaacctgt
     7861 gattatcaaa agctatcgcc actatattga tttacagcgt tttaaaggta cacttgtgga
     7921 accgccggga caaaaacaat atgctttgta ccaaatggct gtcttagttt ggctaacaca
     7981 aacgaagacc ggtgatttgg atgaattaca tttaaccaat ctgaaccatg cattctttgc
     8041 agatgtcgcg cacagaggca ctgggttttt agcaaggaat cagtcatttt acaaacaaga
     8101 ctttgtgcgt ttcttgcaaa agaaaatcaa acaaagcaat tttttgatag tcaaccatgc
     8161 atttttagta caagaaacac agcgaaaaga accattgctt ccagctagtc cttatttgtt
     8221 gattgatgaa gtgcatcatt tgccggaaat tgctgaaaaa gtaaatgaca aacgactaag
     8281 tattaactac ttccataaac aaattcagca actggaagag ccgaatcagt tatttgaccg
     8341 catacaaagt tatttgccga aggaacatga agccttgcgc tggttgtcga tttatcgaga
     8401 agaactctct gcactatgcg aagcgcagat ttgcgtggca gagggattaa tgaacttagt
     8461 aagcagcaag caacctaacg gacaatatcc agaagaagtc atgatgacaa aagaaatgtt
     8521 ggatcagctg ccactggaat ctggaacagc aatggatcat ctgcaacttt tttatcaaga
     8581 gatccaacaa ctacaatcac agatgcgctt gacttttgag attatccaag aaagttggac
     8641 caaccagatg cggatcgatt tagcaagttt atatagctta tttgatcaat tagacaagca
     8701 atacttgctg atggaccaat ggctagaaga ctggcgagat catttgatcc attggttcgt
     8761 tcccgggaat acagcacagc agatgatttt tcatctcctt gattttcaag cagctatgtt
     8821 gccgtcaact gtgtggtatc ctcgatatga ccatattctt tatattggag gaacactgaa
     8881 gatcggacct aatcgacagt atctctctaa acgacttggc attgaagcag cacctcttaa
     8941 agtgattgct tctccttatg attatgagaa acaggcaaga atctatgtgc cgaaagaagc
     9001 acctgcagtc catcaagtca gcaatcaagc atatatcgat tatttagaag cagcactcac
     9061 aggattgatt gaacaagaag atcggccgat ccttgtttta ttcacttctc atgatgtttt
     9121 gcaaaaggta tatcagaaaa tgcatttgtc tatgctagaa aaaggacgtg aaattcttgc
     9181 tcaaggattt ggcgggagtc gggaaaaact tttgaaacgc ttcattttgt cagaaaaaag
     9241 cgtcttattt ggtgctgaca gcttttggga aggcgtagat ttacctggag atgctttgca
     9301 gattgttgta gtcacacgtt tacccttcga caacccgtta cgtccgatgg tcaaagctag
     9361 gaatgcttat ctggaatcag aggggatcaa tcctttttat caggaatccg tgcctaaagc
     9421 agctttgaag ttacgccaag cattaggtcg tttgataagg acggagacag atcgtggcgt
     9481 attacttatt ttggatcgga gattagtcac tgcaaaatat ggtgcacgaa tcatccatgc
     9541 attaccgaaa aaagtaccga taaaagagct agctatagat gaaatctatc aggatatcca
     9601 tgaattctta aagaaaaatg aagaaggaag ttaaaggtgc cgtctttttt catcattaaa
     9661 atctgctata atgaaaagga atgaagataa aggagcgacg acccttgaag aaaaaacaga
     9721 caaaggaaaa aacgattaat cgcgtgttgc ttggcttgat cgtattttta ttagcggtca
     9781 tcgtgatcag ctcgattttt tacttgcgtt ccagtcgtcc ggcggtccag gcgaaaaaag
     9841 aagcagtaga aatcgcaaag aaatatgcaa atctcgagga agccgatcat ttttactggt
     9901 ttactcgaaa gaaaacgtac ttttcattga cgggtacgaa tgataaagga aaagaaatcg
     9961 ccgttatcat tcctaaatct ggtgaaaaag taaaagtatt ggatcaaaca aagggactga
    10021 ctgaaaacga agcaaaacag acaattgctg cggcccatcc tgaaatccaa atcgaaaaag
    10081 ctgctttagg gatgtatgat gatcagcctg tgtgggaagt agtaggaaaa gaaacaaatg
    10141 ggaaactgaa ttattacctg attggctttg aatctggaga tgaagtcaag acaatcaagg
    10201 gaatttaaaa ggtaaaggaa tgaatgggat ggagttatca aaaagaacaa aacgattaga
    10261 accgtctgtc actttggcag ctgcggcaaa ggccaaggca ttaaaagcaa aaggcagaga
    10321 tgtgctgagt ttgactgtgg gagaaccgga ttttgcgaca ccagaaaaca tccaagaagc
    10381 agcaatcgaa gcaatccgca atgggaaagc tagctattat acaccaacag caggaatccc
    10441 agagcttcga caggcaatcg ttgattatct gaagaaaaac tatggacttg tctatgaacc
    10501 ttcacaaaca gtcgtaacag acggagcgaa atttgctttg tatacccttt tccaaacgat
    10561 ccttgacccg caagatgaag tcatcattcc tgtgccttac tgggtcagtt acggtgagca
    10621 agtaaaactg gcagaaggac ttcctgtctt tgtgaaaggg gaagaatcca atagctggaa
    10681 agttactgtt gagcagctag aacaagcacg ttcagaaaaa acaaaagccg taatcatcaa
    10741 ttctccatcg aatccgactg gaatgattta tagcaagaat gaactgcagg caatcggtga
    10801 atgggcagta aaaaatgata ttttgatagt tgctgatgat atttatggcc gtttagttta
    10861 taatggcaat gagtttactc caattgcaac gatttcagaa gcaatcaaaa atcagaccat
    10921 catcatcaat ggcgtgtcta aaacatatgc gatgacaggc tggcgcattg gttatgcggt
    10981 ggggaattct gagatcatca atggaatgat tgctgttgct tcccagtcaa ccagtaatcc
    11041 gacagcagtc agtcaatatg cagctgttga agcattgaaa ggcgagcaag atacagtgga
    11101 agaaatgcgg aacgcctttg aagaacgcct gaatacgtta tatccgcttg tggcagaact
    11161 gccgggtgtt tctcttgaaa agccacaagg agctttttat ctttttccta atgtaaaaga
    11221 aacgctacgc atgtgtaaat atgaaaatgt cacacaatgg gtagaagatc ttttagaaga
    11281 aacaggggta gcgcttgtga ctggcgaagg ctttggggca ccagaaaatg tccgcatgag
    11341 ttatgccact gatcgcgcta cgttagaaga agcggtacgc agaatcaagc aatttattga
    11401 gagtaaaagt caaaattaat cctgaagaaa ttcaaggaat ataaaaggag agtcatacgt
    11461 ggaacaaatt caaatcatcg attcgaaaaa ccatgtggga gaaacagtaa caatcggcgc
    11521 ttgggtcgca aataagcgat caagcggaaa aatcgcattt ttgcaattaa gagacggaac
    11581 agcctttttc caaggtgtag ttgtaaaaag cgaagtgccg gaagaagttt tccaaacagc
    11641 taaaaatcta caccaagaaa catccgtgtt agtaactgga gaaatccgtg aagacagtcg
    11701 ttcaaaattt ggttatgaaa tcggaattac aaatgtggaa gtggtaagcg agagccacga
    11761 ttatccgatc acaccaaaag aacacggaac agacttcttg atggatcatc gtcatttatg
    11821 gctgcgttct tcaagacaac atgcgattat gcagatcaga aatgaaatca ttcgtgcaac
    11881 gtatgaattc tttaatcaac atcattttgt caaaatcgat ccgccgatct tgactggttc
    11941 tgcaccagaa ggcactacgg atctattcga aacaaattac tttgatcaaa aagcttattt
    12001 atctcaaagt ggccaattat acatggaagc tgctgctatg gctttcggaa aagtcttttc
    12061 attcggtccg actttccgtg ctgaaaaatc aaaaacacga cgtcatttga tcgaattctg
    12121 gatgatcgaa ccagaaatgg ctttcactca tcaagaagaa agtttagaag tacaggaaca
    12181 atatgtagca ttcttagtac aaaatgtttt agatcattgc gaatacgcat tagatgtact
    12241 aggacgagac aaagaagtct taaaaactta tacaaaattg ccattccctc gtattactta
    12301 tgatgatgcg atcgaattac tgaagaaaaa tggatttgat gacatcgaat ggggcgaaga
    12361 ctttggttca cctcatgaaa cgttcattgc gaattcattc gaacagcctg tctttatcct
    12421 aaactatcca aaagccatca agccattcta catgaaacca catccaacaa gagaagacgt
    12481 ggtgatctgt gcagatatga tcgcaccaga aggttacggt gaaattattg gtggaagcga
    12541 acgggcaaca gactatgatt tcttgctaga acaaatccgt aatcacggtt tggatgaaaa
    12601 agaatattca tggtatcttg atctacgtaa atacggttct gttccgcact ctggttttgg
    12661 tctaggcctt gaacgaacag tcacttggat tgctggtatc gaccatgtgc gtgaagctat
    12721 tccattccca cgtttgttga accgaattta tccataagag gttgtgaaat cagtgccttg
    12781 acctgagtat tagagaaaca aaacggaaaa atagcttctc atattttact gttttttgag
    12841 ctaatatcga gggtcagctg attgaacacc gtttatatca agaggttgtg cgtctgccgt
    12901 tcagctccga gtcacaagga gtaatttcaa aaaaacattt tttcatgttt gatgactatt
    12961 gtgacttgtg accaaggagt tggccggaga gcaacgttta tttaaaaaaa agaactgcga
    13021 actctcgcag ttcttttttt ttaaatacgg gataaaggaa gtttccagca gataagagaa
    13081 gaaagcaaaa gaaattgcta tttgattcac aaggttctat aacgaaatcg caatcaatca
    13141 aacatataca aagaaggtta ttcaaatgga aatctgattt gatgatgctt ctgctgttga
    13201 aataaagcag catctagcac ctgaaaacaa actaatagta acattcgaag atggagtagg
    13261 tccgtatttt cagcatgcaa tgatccatat gtaagttcaa ttcacccttg aaatcatcgg
    13321 accagataaa gttatggcca atctatccca agcaatctag aagagatatt agtaaaggaa
    13381 catttactgg aagtcttaga tgagcctata aatatatgtt ctgatggcgt catcaagtgg
    13441 tctgattgac ggaagcttag gtgtgatcga tctctctgga ccaaacaatg aaggaatcaa
    13501 ggggaatcca gcacgttaag aaaaaaatag cataaaaaac tagacacttg atgagcgttc
    13561 attcaattgt ttgaagggac taggctggtg tcatttttta tacatatatt ttctctttcg
    13621 tcttgatagg gcttatggga taatataagg aagaaaatca tcgttttatt caaaaaggag
    13681 tttttgacaa atgaaaaaac gtatattatt tatcggtgac agcattacag acgcaggaag
    13741 agaccgagca gaagcaactg atctaggtaa aggttatcca cttttgattg ccggaaaact
    13801 aatctcccaa tatccaacga tggaatttga atgcatgaac cgtgggatag gaggagacaa
    13861 aattgcagat ctgcaagtac gctggcgaga agattgttta gctttacaac ctgactatgt
    13921 atcgattttg atcggaatca atgatacctg gcataatact agcgatcagg ctatattcgg
    13981 aactgagaaa tctgctcagc aatttgaatc cgtttatcga aaattactaa atgaacttca
    14041 aaaagcggga atctgcaaca tcatcttgat ggagccgttt gtacttccta taaccgacga
    14101 ccgtcatggc tggcgtaaag acttagaccc taaaatccaa attgttcgta aacttgctaa
    14161 ggaatatggc gcattgctgg ttcctttaga tggcatattc aatgctttag ggattgctta
    14221 tggtttttcg aaatatacaa gagaagatgg ggtccaccca acgattggcg gacatgagat
    14281 cattgcacaa agctggatag atgcaattgc cgcagtcgat ttttttagtg gagataaaaa
    14341 tgagcgaaag aaaagtgaga aatgatggaa atacggtggg cagtaaaaga agatctacct
    14401 caaatcaatc agctgattac tgatcatcca gaatcattcg taaaagcaaa aacggcagct
    14461 gacctaaatg ataagaataa actattgctc gttgctgtaa caaaagaaaa acggattatc
    14521 ggttttgcgc aagcggacgt gcaacagtca gaagaacggg tgggtcagcg accatcagga
    14581 aaactaatcc aacacacatt agtaacaaaa gaaaatacgg aagaaatcca aaaaaaattt
    14641 gcagaatatt tgatgctgga agctaaaaaa agaagaataa aatcaatttt tgcccagttt
    14701 taatcaaaaa cagtaataga aggagaaata caatgagttg tttaggaaat gtcatctggt
    14761 ttatattcgg cggactaatc ggtggtctta gctggttagc agcggggata ctttggtgta
    14821 tcacgatcat aggtatccca atcggtatgc aatgttttaa gatcgccttc ctttcttttg
    14881 cgccttttgg caaagaagta atttatcacc agtctggcat gtcattgatc gttaatatca
    14941 tctggctgat cgtttcaggc ctaccaattg ctctcgcaca tgtcgtcagc ggcatccttc
    15001 tatgtatcac gatcataggg ataccttttg ccaagcaatc tttcaaactt gctcgattgg
    15061 cgttgatgcc attcggtgca gaaattgtat aaaagagaat aataaaggtt agataaagca
    15121 tagagtcagg tgggatacat gtatttcacc tgactctatg cgttttcctg tataagttct
    15181 tccatgtgac ttttacgtct tttatttata tggggttact gtttatggaa agttgaaata
    15241 attttcatta aagaactctt tctatatttt tgaaagcgta gtggagcttc gtatatctgg
    15301 gaaggacatt ttgcagggat tgaaaaaaga tattgtccta tcgaaaaatt aatgaattta
    15361 gacaaattgc cagcaacagg cttcaaactt agttgctatc ctgtcaagat caagaaggca
    15421 agtgcgggtt ggataagagc agtggcaatg atcgaagaga aaaagaaaga ataagccaaa
    15481 acatctgtat ggaagaaatt ttccgatgca gatgtttttc attttttctt tcggatacct
    15541 tgacatatga ataaccattc atttataatt agttatgaag agatattcat atgttgaggc
    15601 gaggaggtca ttaaaatgaa aagttacaga ttagaaggtt tagattgtgc gaactgtgca
    15661 atgaaaatcg aaaaaggagt tcagaaaatc aatggagtca aggaagcaac ggtaaacttc
    15721 acttctggaa aactaacgat tgacgcggag gaagatcatt tggctacgat tgaacaagaa
    15781 acaaaaaaag tagtgaagga attagaacca gatgtcaaag taacagaaat agataaggaa
    15841 aaagtatctg aacatggaaa tgaaaaagag agaaatacgc tgttccggat tttattttcc
    15901 cttgcaggta tcgctttatt gctattattt gattttaatg aactaattcg cttgataggg
    15961 tatttattga tttatctgct gataggatat gatgtagtga agaaggcagt gatgaatatc
    16021 gtcaaaggaa aaatctttga tgagaatttt cttatgtctg ttgctacgat tggcgctatg
    16081 ttgatcggtg aatatccaga agccgtagca gtgatgctat tttatcaaat cggcgagtat
    16141 ttccaaggat tggcagtcag tcattcaaga aaatcgattc gcgaattgat ggcgatccgt
    16201 ccagaaacag ctcacgtgca gacggcggaa ggattgatga ccgtgaaccc tgaagacgtg
    16261 ctgatcggtc agtttgtact tgtgaagcct ggtgaacgtg taccgttaga tggaacgatc
    16321 atcgaaggag aatcattagt cgatacgtca gcacttacag gagaatcagt ccctaaatct
    16381 gtatatgttg gtgaaacagt attaagcgga tttatcaata aaaataaacc atttttagtt
    16441 caagtagaaa aatcttatga aaattctact atcagcaaat tattagaatt agtagaaaat
    16501 gccagcagta aaaaagcacc agctgaaaat ttcattacta aattcgcgcg ctattacaca
    16561 ccagtcgttg taggattggc cgttttatta gctgttttac ctccacttgt tgtttctgga
    16621 gcggcgtttt ctgaatggat ctatcgagca ttgacatttt tagtgatctc atgtccatgt
    16681 gcattagtga tttccgtgcc acttagtttc tttggcggta tcggaggagc aagtaaaatc
    16741 ggtgtattag taaaaggttc aaattacttg gagttgcttg cgcaaaccga gacagtggta
    16801 ttcgataaaa ccggcacatt aacgaaaggc gacttttcga tccagacgat cgatacaaaa
    16861 atcgatccaa agatattcat gcaatatatt gcgagtgcag aacagttttc tacacatccg
    16921 attgctcaat ctgttttaga aggctacgca ggtccgcttt taccaacagc taatatccag
    16981 gaatttgcag gtgaagggat cttagctgaa gttgatggca aacaagtatt agtaggtaat
    17041 cacaaattga tggaaagatt tgaaatctct tttccttcaa gtcaagaaat cggtacattg
    17101 ctttatctag caatcgatca aagttacagt ggttatcttg ttattgcaga taccttgaaa
    17161 gaagatgccg tagacgcatt ggttcaatta aaacaggctg gtgtgaaaaa cacagtcatg
    17221 ttgacgggcg actcgaaaaa aattgctgat catatcggga agcaagtagg cgtggacaag
    17281 atatatagcg aattgcttcc agaagataaa gtgcagcggt tagaggaaat cttacaaagt
    17341 aacaataaaa agaccgcatt tgtcggagat ggaatcaacg atgcaccggt gctagcaaga
    17401 gcagatgtag gaatcgcaat gggtggattg ggaagcgatg ctgcaattga agcagcagat
    17461 gtagtcatca tgaatgatca accatcgaag attgcagaag caatccattt agcaaagaaa
    17521 acattgaaaa tcgtcaaaca aaacattgtc tttgctattg ggataaaaat tttggtactt
    17581 tccttaggtg cttttggttt tgcatcaatg ggagatgcag tatttgcaga tgttggggtg
    17641 acagtattag ctgttttgaa tgccatgcga agcttgcatg taaaaaataa acgttgatca
    17701 atgaagagga cgaatgaacg tcctcttttt tttatatcct tttcttaatg aaaaatgtaa
    17761 agaaaataga taggattata aaataactaa tgtttttaat tttgcagaaa attcaaaata
    17821 gcttgaaatt caataaggtc aatgaaataa aagaaaataa cttatttttt tgatggaaaa
    17881 aatatgaaaa aacgatgtgt attaaataaa ataatacaca cataaaataa cactgtcttg
    17941 taagtttgtt aaaaattgaa tatgattaca tctggataac aaatttttat cataaaggag
    18001 agaacgaatg aacaacaaac aattacgctg gtttactgtt gcgttaattg catttaacat
    18061 ggtttggggc atggggaatg tagttaataa ctatgctcag caaggagtat cagttgtcac
    18121 ctcttggcta ttgattttgg ccatttattt tattccatac gcattgatcg ttggacaatt
    18181 aggatcagcc ttcaaggata gtaaaggagg cgtcagttca tgggtcgaaa atacgacatc
    18241 taataaacga ctggcatact atgccgcttg gacttactgg gtcgtccata ttccttattt
    18301 ggcacaaaag cctcaagcaa ttctgattgc tggtggttgg gcagtccaag gaaatggaaa
    18361 tatcgtaaat acgatgtcag tacaaatggt agcagttatt tcacttatta tatttcttgc
    18421 ctttttatat ttatcaacaa aaggactttc tactttgaaa gtgattggcg gactggccgg
    18481 aacagcgatg ttcgtcatgt cgatcttatt tattctttta gctgtaacgg caccgttcat
    18541 caatccaacg atggaatttg ccacaccaca tatgaatcaa gtgaaaacat atattccaac
    18601 atttgatttc agttatttca caaccgtttc gatgctagta tttgcagttg gaggggcgga
    18661 aaaaatatcc ccttatgtca actctacaag aaatcctgca aaggaatttc ctaaagggat
    18721 gatcttctta gcagcaatgg tagggatttg tgctgtatta ggctcagtcg caatgggtat
    18781 gctgtttgct agcgataata tccctaaaga cttgatggca aatggggcat acagtgcttt
    18841 tcaaatttta ggtaattact atggtatcgg taactcattg atgatcattt acgcattgac
    18901 aaacatgatt ggacaaatct ccgcattagc cttttcaatt gatgcaccac taaaaatctt
    18961 gttagcagat gcggatccag aatttgtacc aaactggcta cgtaaacgta atcgtaaagg
    19021 tacattggtg aatggttatc ttctgacagg tatactagta ggaatcatta ttttgttgcc
    19081 gatctttggt atcaaagata tgaatgaatt agtaaaatgg ttgacgaact tgaactcagt
    19141 tgtcatgcca atgcgttacc tatgggtgtt cttggcatat atgatgttga ataaagctta
    19201 taagaaattc aattctgaat ataaatttgt taaaaatcca aaaatcggtt ttatctttgg
    19261 tgcttggtgc tttgccttca ctgcgtttgc atgtatccta ggaatggtgc caaaagtaga
    19321 ttatactgct gatcctaaag catggtggtt ccaattattc acgaatatca tcacaccaat
    19381 tgtcttgatc ttattaggta tgatcttgcc agcaattgct cgtcgagaca aaaacaaaga
    19441 aattactgaa ccagaaacag tggttcagcc ttaaaataga aatacttgtt acaagaggtt
    19501 gtgacagaag ctacttctgg aacaccgtga atcagaggtt gtgaaaaagc tgtcctgcat
    19561 caagtaataa gaacagccaa acaaaaatag ctcctcatat tttgccgttt tttgagctaa
    19621 tgctgaaggt cagctgattg aacaccattt attcgaaaca agggactttg acacgacttt
    19681 tgtcacagtc ccttgttttt ttgcggcgtt ataagtggta tgatcgaacc aaattccaaa
    19741 gagaagtgag ggagaagaat gaagatcatc gtgattggac aaagtgggtc gggaaaatcg
    19801 tccctcgcaa ggaagatcaa agaaatcacc ggctttccgc attcaggcaa aaaagtggtt
    19861 tttgcaagaa cagcaatcgt ttatagtatc taatccgtca tggatcgttg aaggaaatta
    19921 tacttctacg ttagaggaaa ggattaaaga agcagataag atcatttggc ttaaagtgcc
    19981 gcgttatctc gccatctacc gagtagtttg gcgttctcta aaaagaaaga taaacaaaaa
    20041 atctcggcca gatatgcctg aatcattttc ggagaaacta aacaggaaat acttagaatt
    20101 tttatctttt atctggcatt ttgaaggaaa caatgaacca aaaatacagc agctgatcca
    20161 agtagctaat gcaagaaata aactgatcat ccttaaaaca agacgagaga aacaagaatt
    20221 tttaactaaa ttgaaaatag agagcaaaaa taattgacag tttttgttta caagcgtaat
    20281 ctgtattcat aagctaatga ttacatttgt aaacgaaagg tgtgaaataa atggaaaaag
    20341 tcaaaacgcc agtaaagatc agtgattcag agtgggagat catgcgtgtt atttggacac
    20401 ttggacagac gacagcccaa gaaatcacgc agatcttagc tgattcgatg gattggaaac
    20461 cagcaacgat caaaactttg ctgggacgtt tggtaaaaaa agaagtgatc tggacagaac
    20521 aaaaaggaaa aaaattcatt tatcatccag ctgtctcgga gatggaaaca gttcgcagtg
    20581 cgacggaaaa tcttttttcc catatctgtg caaaaaggat tggagagacg attgcggatc
    20641 tagtagaaga agctactttg actcaagaag atatcaatga gattttgaaa caactggaac
    20701 aaaagcaacc agtagatacg atcgaatgta actgtatccc aggtcaatgt gaatgtaaac
    20761 aacatcaata ggaggaagaa aaaatgaaac aacaattttc aatcgaaggt atgagctgca
    20821 atcattgtgc agcaagagta gaagaaacag taagcgcact tgacggcgtg caaaaagtga
    20881 aagtaaattt gaaaaaagca aacggtacgg tcaagtttga tgaaacaaaa gttcaatccg
    20941 aaaagatttg tcaagcaatc aatggattgg gttataaagc agaggtgatt tgatggcaac
    21001 agcagaaacc aaaatggata cgttcgtcat tacaggtatg acttgtgcaa attgttctgc
    21061 taggatcgaa aaagagctga acggacaacc tggtgtggtc aatgccacag tcaacttggc
    21121 cactgaaaaa gcaagtgtca aatatgaagg gacgaccact gaaaaattaa tccaaagcgt
    21181 agaaaacatc ggttatggtg caattttgta cgatgaagcc cacaaacaaa aaattgcaga
    21241 agaaaagcaa gcgtatttga aaaaaatgct attcgatctt atattgagta cggttttgac
    21301 tttgccgttg atgttgtcaa tgattgctat gatgttagga agccatgcgg cgattgttca
    21361 cttttttcat tttccaatcg tccagttagt gctgtctgct cctgtccaat tttatgtcgg
    21421 tgctcgtttt tataaaggtg cgtaccatgc aatcaagacg aaagcaccaa atatggatgt
    21481 attggtagca attggaacat cggctgcctt tgcattgagc atttacaacg gatttttccg
    21541 tggacacccc caagatcttt attttgaaag cagcagtatg atcatcacgc tgattttgct
    21601 cggcaaatat ttggaacata cagcaaaaac gaaaacaggt aatgcaatca aacaattgat
    21661 gtctcttcaa acaaaaaccg cccaagtgat aagaaacggg aaagaagaaa cgttagcgat
    21721 tgaagaagta gtcgttggtg atcaactagt catccgtcct ggtgagcaga ttccagcaga
    21781 tggtcgaatt atttcaggaa gcagtgcgat agatgaaagt atgcttactg gtgaaaatct
    21841 tcctgtagaa aagaatccgg atgacacgct ttttggcggg acaatcaata cgaatggtct
    21901 gctacacatg gaagtcacac aagtcggcaa gcagacagta ttagcgcaaa tcattcaaat
    21961 ggtggaagat gctcaaggga gcaaagcccc aatccaaaaa atcgcagatc ggatctcagg
    22021 gatttttgtt ccgatcgtat tagtcatcgc gtttatcacg ctcatagcta caggtttgat
    22081 cactggtgat tggcaactcg cattgatcca tagtgtctct gtattagtca ttgcgtgtcc
    22141 atgtgcatta ggtttagcga ccccaacagc tattatggta ggaacgggtg ttggtgcacg
    22201 aaatggaatt ttaattaaag gcggagaagc attagaagca gctgctcact tagacagcat
    22261 tgttttggat aaaactggaa cgattacaga aggaaagccc aaagttacag atctagtcgg
    22321 ttcaaaagaa gtcctatcta ttttttatac tttagaacaa gcttctgaac atccactagg
    22381 taaagcaatc gtggaatacg gaaaactgca agaagcagca acatacgata tgattgattt
    22441 tacagcccac ccaggtgctg ggatcagcgg tacgattaat ggagtacgct attttgcggg
    22501 tacacgtaaa cgattaattg aattgaacct atcatttgat gaataccaag aacacgcgtt
    22561 agaattagaa cagcagggaa aaacagtcat gtttttagct gatgaaaagc aagtgatcgg
    22621 gtggattgcc gtggctgatc aaatcaaact agaagccaaa caagcaatca agcagctcca
    22681 gaataaagga ttagatgttt ttatgctgac aggagacaac aaactggcag ccgaaacgat
    22741 tggtaaacaa gttggtattg atccaaagca tatctttgct gaagtacttc cagaggataa
    22801 agcagcctac gtagaaaaac ttcagaaaga tggcaaaaaa gtcggtatgg caggcgatgg
    22861 aatcaatgat gcaccggcct tagcattagc tgatgtcggt atggcaatgg gaagtggaac
    22921 ggacattgcg atggaaacag ccgatgtgac gctgatgaat agcagtttgg catccattgc
    22981 acaaacaatc gagttgtcta ggttgacatt gagaaaaatc aaacaaaatc ttttctgggc
    23041 ttttgtctat aatacgattg gtattccttt tgccgcacta ggctttttga atccaatcat
    23101 tgcaggagga gcgatggcgt ttagttccgt cagtgtattg ttgaactccc tgagcttaaa
    23161 tcgacacatg aaaaagtaag agaagggatg gagtaaaaat gaatgggaac gatatggaga
    23221 aaaaacatga gcataaaaaa gaagtagtaa acaaagaaag tacagaatct catgaaaaac
    23281 agatggagat gaaacatgac catagtcaga tggatcattc catgcacatg ggacataacc
    23341 atggagatat agcaaacagc aaacaaatgg accattcgat gcacatggat cacgaacacg
    23401 gcggcatgga tcattccatg cacatgggga atttcaaaca aaaattttgg ctatcgctta
    23461 tcctagctat cccaatcatt cttttttcac caatgatggg aatggaattt ccatttcaag
    23521 taacgtttcc tggttctgat tggctcgtat tgatcttagc aactatacta tttatctatg
    23581 gcggtcagcc atttttaagt ggagctaaga tggaattgaa acaaaaaagt cctgctatga
    23641 tgacactgat cgcgatgggg attacagttg catatattta tagtgtctat tcgtttatcg
    23701 caaatctgct caatccacat acacacgtca tggatttctt ctgggaattg gctactttga
    23761 tcgttattat gctactaggt cactggattg aaatgaatgc tgtgtcgaat gccagcaatg
    23821 ctttacaaaa actagcagaa ttactgccag aatcagtgaa acgcttgacg aaagatggaa
    23881 aagaagagac agtttcattg aaagaagtaa acgaaggtga tcgtttgatc gtccggtctg
    23941 gtgataaaat gccaacagat ggtgtaatct tgaaaggtga aacaattgtt gacgaatcag
    24001 ctgtgactgg cgaatcaaga ggaatcaaaa aacaagccaa tgacaaagtg attggcggtt
    24061 ctatcaatgg ggatggaacg atcgaaatcg aagtaactgg aactggtgaa aatggttatc
    24121 tagcgaaggt tatggaaatg gtgcgaaaag cacaaggaga aaaatccaag ctagagtcat
    24181 tatctgacaa agtggcaaaa tggctgtttt atgtcgcatt aattgtgggt atcctggcat
    24241 tcatcgcctg gttgttcttg acagatcttc ctaatgcatt agaacgtatg gtaacagtct
    24301 ttatcatcgc ctgtcctcat gctctaggtt tagctatccc attagttgtt gctcgctcca
    24361 catcaatagc agctaaaaac ggattacttt tgaaaaaccg caatgcactg gagcaagcca
    24421 atgatctaga tgtgatcatg ctggacaaaa caggaacact aacagaagga aaatttactg
    24481 taacgggtgt cgaagtactt gatgatgcgt tcaataaaaa tgaaatcctt caatatctag
    24541 gagccttgga agcgaatgcc aatcatccat tggctgttgg cattatgaat tatttgaaag
    24601 aacatgaaat caagccttat caagctgaaa atctaaaaaa tctttcagga gtcgggctag
    24661 aggcaacagt caaaaaacaa caagtgaaaa tagttaatga aaaagaagtt gagcgtctcg
    24721 gattaaacgt agaacaagca ttattgaaac cttaccaaga acaaggaaat accatcagct
    24781 tcctgatttt agaaaatcat ctagctgcaa tcgttgcttt aggtgacgta gtaaaaacag
    24841 aagcaaaaga atttatccga acattgaaag aaagaaaaat cactcctgtc atgcttactg
    24901 gtgacaataa aaacgctgcc caagcagtag cagattattt agggatcgaa gaatattatg
    24961 gcggtttatt accagatgat aaagaagctg ttgtccagaa ataccttgac caagggaaaa
    25021 aagtaatcat ggtgggtgat gggatcaatg atgcgccaag tttagcccgt gcttcaatcg
    25081 ggatggcaat cggtgcaggg acagatatcg caatcgattc tgcggatgtc gtattgacaa
    25141 acagcgatcc aaaagatatt ttgcattttc ttgatctagc caagcaaacg cgaaagaaaa
    25201 tgatccagaa cctctggtgg ggggcaggtt acaatattct tgcaattccg ctagcagccg
    25261 gaattcttgc gccaattggt atcatattaa gtccagcagt tggtgctgtc ttgatgtcgt
    25321 taagtacggt agttgtagct ctaaatgctt tgacattgaa aatcaaataa taatgaaaaa
    25381 aggttgtgac aaaaaacgtg tcacaacctt tttttcgagt aatcgatact caatcagctg
    25441 gttctcggca ttccagaagt agattctcca gaaattttat cttatttttt gaagcggctc
    25501 ccttttgtca gaattttttt gtataccgtt tttcttatta tacgcgttat ttctaaatag
    25561 gtttttttat cgaattttac cggatctgct tgtcgtccat atatttctgc ttcatattga
    25621 gtagttaatc gaatgaaacg cagatctagc ttgaattctt gttctattcg caggctatat
    25681 tcctgcaaag attctgcggg tttgcgcggt accaatgttt ccaaagggtt aagaagtttt
    25741 tgatatgcaa tcgtattagt agaagcaaaa aaatgaagat agataagata acttgtccag
    25801 cgcagagatt ttctgaataa caatagaaag aacaacaaga cggataaaca cactccaagg
    25861 ctgaataaga cgattttata agctggtgtg agtgttgttt cttctgatgg aatgacctca
    25921 gatctctcac tggaaatagt ttctgccata ttttcgcttt catttggttg ttcgatagca
    25981 ggctggacgg tttcggttgt ttcagcaact ggttgtgaac ccattggatt ggcaaatgaa
    26041 ggggttggtt caaatggaag ccagccaaat ccaggaaagt atacctctgg ccaagaatga
    26101 gcatgactat tgagaatgct gtattcctca ttcccttgat tatctgtgcc tgttctgagc
    26161 ccatttgtaa aaccttttgt ccagcgagct gggataccaa gtgttcgaag aaggacgacc
    26221 atagaagttg aaaagttgtc acaatagccg acttttgaat caaagaggaa ataatccaca
    26281 taatcgtgtt ctttcggagt atgcccggta tccgttttgg aatagcggaa atttccgctt
    26341 gtttttaaat actgttagac agcttcgact ttacgaatta aagttgcttc atttttggtc
    26401 aattcgaccg ccaagtcctc aatacgttta ggcaaacttt ttggcaattg aagatttgtc
    26461 tgctgatttt ctaaatcatc agcttttaac tgactgcttt ttaattcttc tctcgtaaaa
    26521 actaaccttt ctgtttgtaa agttgcagaa cgtgtcgatt cattcgggac aggaatgaat
    26581 cgctggcttt caggcaaata gtaaagcgtt tgtccactag ctaatgaaaa atcagtcaag
    26641 gtagtatttc cataaggata aggtaagaaa gcttgttttt ttagggtcaa tgtaatgttt
    26701 tctttgtctt ctataacggt ttggtagctc gtgatgtcaa cagggaattc ttggattggt
    26761 tggatgggtg cgtcctgatc ttctatccat ccagaaccgg tgtaatgatt tttattttcg
    26821 atcttccaat agccatttcc tttttggttc gctgtaaaaa caacttcgcc attatcatat
    26881 aaaggtccac caagctgttc atcattctca ctgaagcctg ttcttgcact tccggttaat
    26941 tgatactcat ggagtgtgtc ataaagccct tcatcattaa gatattctcg gatcggttca
    27001 ctcgtttcct cgagagattg gtgtactttc ggaagatata aaggcaagat agcgctaaaa
    27061 gttaagaaac aaataagcag aactgtagtc aatgactgga atcgagtgtt tcccgacaac
    27121 aaccggatgg agaaaaattg ccttgctgcc agatacacga acaaaacagt tactaccgca
    27181 atcatttcgt acagtaaatc ttttttccga aaaacggtaa gcatcatgaa gtaagccatc
    27241 aaagaaagaa agggtgcgta ccaatagtcg taatccacgg tcaatgtaat aaataaatag
    27301 atcagcaaca ttatgagaaa aaaagctgtc ttttctggca aataataaag tttaccttgg
    27361 gatagatgga agaattcctc tgtaactgac gaaaaaaact gtaagatcca taatatggaa
    27421 aatgtcttcg aaggaaaata taaaaacaaa caacctatca ttactggcaa agaaagcagc
    27481 aaacgtaccc attttttagg aatacagcag acaataaggc ataggacacc aatagttagg
    27541 ataagaaggt agctgttttg caattgatta gctactacaa atatcggagc acctacactt
    27601 agtatcacaa aggagtaaac gccacgcagc catttttccc gtttaatcgt caatccattc
    27661 acctcctggc aatgaacata tcttgtcttt ttcttggacc atgagttgtt tttctacgaa
    27721 ataaacaaga taagccgttc gatcttttga caatgtttca atagcttctg agacttcagg
    27781 agaattctca ggaacaaaga ggacgatttg tttttttgca tattttttca agtgtgcgaa
    27841 aaaagctttc tcatcgccag cttccaaaga agcaaaatag gtatgaccgg ggtctttgcc
    27901 atgaaaggcg cggttgccta atatcagaag ttccggctgc ttttcttttc tcaaatgcca
    27961 taaagaaaaa tacaagtcta gcagaggttc aaattttgga ctgggcgaac cccaaaagca
    28021 aaaaagagga gaacattctt cttcttgata atcgtattca cggtataacc actcttgagt
    28081 atgagcagac aatttccaat cgattcggtt gaaagaatca cctggacgat aagcgcgatg
    28141 ttcccgaaaa tcaagacctc tttggtacgc gttcagctgc tgtttttttt ccagaactct
    28201 ctgtaatttt tctgcttgaa tcttacaaaa agcaggcaga acagtcacag gaaaagagat
    28261 ctctcttttt gcactttttc tgaaaagtcc tagactatca taggctgtaa aaatgacagt
    28321 taatgtttca tggcatcctc tttcttttgg ctgccaaagc aattggactt cttgcggttt
    28381 atttgtaaga atcaaaatct cttgtttttt tctgcaaaga ttgctgggaa gccgatttgt
    28441 aaacgaggga gaggtaaaga aaaagttctc ttttttgcta tggaaaaaat aacctgcata
    28501 ctttttttgc gataaacgag tggctgcaat gtacaagtaa ccgaaagttt ctttagaaag
    28561 ctgcttaatg aaatcaagct ccatgataca taaagagtaa aaaaggccaa caagaaccag
    28621 cctaaagaat tgttgaatac aagagcaaaa agcacaatga tgaaatatac cagaaataac
    28681 acaaaattaa tgaaataatc tttgattttt tccattgtct acctcaatct acctcacagg
    28741 aataggaatt tgtgcaacaa gagtatgaat gatttgtttc ttttcgtctt ccttcaatga
    28801 acgatcgtaa aaaatcaggc gatgggaaaa cacgtaagga actaaatcct gcaaatcttt
    28861 gggcgtgacg taatttctcc catggattaa agcataagct tttgctgcct gaataaagga
    28921 aaggcttcct cgtggactga tgccaagctg gatggcagca tgacttcttg ttgctgacac
    28981 taactgcaag gcataagatg ccacttcggg actgacaaag acattcgcca catttgtttt
    29041 tatttcttct atttcataac tgttcaatac ttcatttaag ttatccaaca ctttttcgaa
    29101 tttatccaaa agtagcaaaa gttcgtcatc aaaagaagga taaccgattt gtagtcggaa
    29161 taaaaaacga tcgagctgtg cttccggcaa aggatatgtt ccttcgtact cgattggatt
    29221 ttgcgtagct aagacaaaaa aatgattgtc tagagggtat gtattgttgt cgatcgttgc
    29281 atgattctcg gccattgctt ctaaaagtgc tgactgagta cgaggagtcg tacgattgat
    29341 ctcatctgcc aacaagatcg tggtaaagat cggtcccgga cgaaattcaa actcttttga
    29401 ttgtgaattg tatacggaaa aaccaagaat atcactaggc agcagatcag gagtacattg
    29461 gactctgctg aaggttccct gtacagcttt tgctagtgct ttgaccagta acgttttacc
    29521 tacaccggga atatcttcga ataagacatg accacctgct aatagggcca cgatcatcaa
    29581 ttggatagtt gaacgtttgc cgatgaccgc tttttctaat tcttatatca actgatcgat
    29641 tttttgtttg gattcttcta ttttttcttc cattttcaca tcaccttctc ataaaatcgc
    29701 tatttatttc attgtaatgg aagggaatac atcctacaag caaagtgatc ttattatgtt
    29761 tttttaaagt acattcgttt tgaaatgaga atacgattaa attgagtaaa ataaaaaata
    29821 atgaggaaga tttgcgtatt taaataaata gaaagggagt tttttatctt tttaggagtg
    29881 aactcatttt gatcaaacaa tatgtttaga aatcaggtga gaaatgatcg atgagatggc
    29941 aaaaactatt atcaaaaaat gcacagaatt tattttcact aatcaatcta atgaaagatt
    30001 tgatctggcg aaaagctgat ttagctgaag aactgaaaat cgatgttaaa acagtggatc
    30061 ggcatctgaa acgtttggcg gaaagcgact gtcccattca gctgattctt cataagaaaa
    30121 ccgttcagtt agtttatgat caaggatata gcgaacctta tctcttgttt gtttttctga
    30181 tccaatcacc cccgttttgt ttactgaaaa atctgctatt aaatgaacct tacgagcaga
    30241 agtacgatcg ttctacgcaa gagcgattga gaaagtggtt tggcgagtac cacctttctt
    30301 tttcttataa aaaagcacag atctttggtt cagaaagaaa agtaagatat ctgctgtttt
    30361 actttttgaa agattttccg catttttttg cagatgatgg agagcagtcc ttttctgaga
    30421 tgttcatcca attattgaag caaagaaagg atccggcaga aatcgagatt ttaggagaca
    30481 gtcgaacact attctttgaa ttgtttcctg aattgctatt tagagaggag cagattttgc
    30541 caataaaaga aaaaaattat ctagcaattt tgcgcttgag ctgtaaccag attactgaaa
    30601 agcggtggaa acggatagaa gagacacaag actatcggaa attgacgatt gtgactgaaa
    30661 agcttgattc gctgttttgg ctgaatagcg aatttgagag cgaaagcaaa tcaaagctga
    30721 taaaagtact ttaccaagaa tggcttcgtt acgtaattgg tatccatgac cggctgatag
    30781 aagaagttcg ttattatcag gaaacattag aaaaatttcc caattccaaa gataaactat
    30841 atcaatttcg gctagcgatc caacaagcac ttgcacaccc cgcagtagag tgggggatgc
    30901 ttttactgaa aacactccag gaacgagggt atttagatgt ccaccctcct gaagtgaaaa
    30961 tcgtcttttt ttttcgctat gaacaccaag aagcaagaag acttgctggg gtactgaaca
    31021 aaacgctaag acatcgaaaa cggatctcta tacatgtatg tactcgaaat aagccgcctc
    31081 ggtatgcaga tctagtgatc accgatcatt tttttccact agaccataac gaagatcaaa
    31141 aaacgtatct gtaccatcct tcatttggta tcgaaagact tcttaccgat atcaattact
    31201 ggttaggcaa aaaccgataa aacctttgga aaaaagatca aaacaagtca gtctgtgcta
    31261 taataaaaag cgattagtaa aggaggaaat ccattggaat taaagaaatt agaagttccc
    31321 acatcttcga tcacagaagt gaaacgatcg ccgatggatg tatttgctca agcgcgagac
    31381 gcgggaactg gcgtatatat atttaatcgt gaaaaagtag ctggcgtgat gctgacccaa
    31441 gaacaataca aaacgctctt gcaagaacta gatgtccttc gtcaaacagt gaaagtggag
    31501 aggaaagaac caaaagaaat aaacgaagaa cctattaaca aaacagcttc cgtcgtatcc
    31561 aatgctgaag ggatggaaga gctggcccaa acattacagc actcgctcat tactggtgtg
    31621 acgattacag caaaaaatct agatgaacga atggtagcac taggttttat tacgaaaaag
    31681 accggatttg gcggagtcgt ggatatgctt agcgagttga tggaaactgg gaaaatcaac
    31741 taccagttaa gaagaaaacc gcaaaatcgg acaatcatag ctgaaatcat aggagagcaa
    31801 aacagtcaat ctcaattgat ggataaaatc atcatcaaga aaatttttct acatgagcta
    31861 taagaaaacc atgttcgcac ttctaggcaa gccaggcttt gaagaccttg ccaaagaatt
    31921 gaacgaacgc ctttaagata agggtttttc gctagattta aaaaatcagt gatagaaaca
    31981 tgttcgctta taaataaaat tagtgatagt tttagtgata gtgagcttaa aaaagcactc
    32041 aatttgagtg cttttttatt tgctcttcta tatagttttc tagttgattc attgatcttt
    32101 ttttcacttc gggagaaata tgggcataga cttgtgtagt ggaaacatct ttatgaccta
    32161 aaaaatcttt gatatcttct aaaggtattc ctgcttgtct cgttctagct gaaaaagcaa
    32221 aacataatgt tggtgttttc ctttcagcat atctatcagc aagatgtaga gtaggacaac
    32281 ctcgtgagcc aaaagtcctg tgcaaatcga gttacaacac acacatgata aagaaacttt
    32341 tgaaaagaac tataaagtat acgttgaatt ggcaagagat tcagcaatga aatatggtat
    32401 tccattaaca ttagacactc cttataacca accaggaatc aaatcgcatt tatgggtaac
    32461 acaaaatatt tggggcgatc atacagatcc ttacggttat ctttctgaaa tgggtgtaag
    32521 taaagaaaaa ctagcctatg atttggctca tggttttacg gatgataatc caactacttc
    32581 ggaggataaa ccagtaattg atccaactcg agcaggtgct gcaaattcta cgctgacaga
    32641 tggaacaaat tacgcccaca ttgatcagtt cggagaaatc gaaaacgcaa acttgcatgt
    32701 agctggatgg cacattgcta attataaata cgagtatatt ttcattatgg actacaatac
    32761 tggaaaagaa ctagctagag taagagctga tgggatttat agaccagacg taaatcaagc
    32821 ttataatact ttaggaaatg ttggctatca tgtatctttc aatatgcgtg atttccctaa
    32881 taagaaagta tacgtcatga tgcgtgcgac aaacgatcca gaaggaaata ctaagggtgg
    32941 agcacaagat tttcatgaca agcgttggta tttaaatatt ccacaacgat aaaaaatccc
    33001 cccctcttt
//
LOCUS       DAFKHN010000030        32782 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFKHN010000030 DAFKHN010000000
VERSION     DAFKHN010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.030"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(56..1534)
                     /locus_tag="LY912_001337"
     CDS             complement(56..1534)
                     /locus_tag="LY912_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955045.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1832..2767)
                     /gene="murB"
                     /locus_tag="LY912_001338"
     CDS             complement(1832..2767)
                     /gene="murB"
                     /locus_tag="LY912_001338"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBM6955046.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2840..3760)
                     /locus_tag="LY912_001339"
     CDS             complement(2840..3760)
                     /locus_tag="LY912_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBM6955047.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3873..4625
                     /gene="xth"
                     /locus_tag="LY912_001340"
     CDS             3873..4625
                     /gene="xth"
                     /locus_tag="LY912_001340"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBM6955048.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5489..6022
                     /locus_tag="LY912_001341"
     CDS             5489..6022
                     /locus_tag="LY912_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBM6955049.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6512..7036)
                     /locus_tag="LY912_001342"
     CDS             complement(6512..7036)
                     /locus_tag="LY912_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955050.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(7029..7502)
                     /gene="tsaE"
                     /locus_tag="LY912_001343"
     CDS             complement(7029..7502)
                     /gene="tsaE"
                     /locus_tag="LY912_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBM6955051.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7625..8605)
                     /gene="pta"
                     /locus_tag="LY912_001344"
     CDS             complement(7625..8605)
                     /gene="pta"
                     /locus_tag="LY912_001344"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBM6955052.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8758..9438)
                     /locus_tag="LY912_001345"
     CDS             complement(8758..9438)
                     /locus_tag="LY912_001345"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBM6955053.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9564..10433
                     /locus_tag="LY912_001346"
     CDS             9564..10433
                     /locus_tag="LY912_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBM6955054.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10459..10974
                     /locus_tag="LY912_001347"
     CDS             10459..10974
                     /locus_tag="LY912_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955055.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(11021..11614)
                     /locus_tag="LY912_001348"
     CDS             complement(11021..11614)
                     /locus_tag="LY912_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955056.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11639..11818)
                     /locus_tag="LY912_001349"
     CDS             complement(11639..11818)
                     /locus_tag="LY912_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955057.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11895..12404)
                     /locus_tag="LY912_001350"
     CDS             complement(11895..12404)
                     /locus_tag="LY912_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955058.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12500..12880)
                     /locus_tag="LY912_001351"
     CDS             complement(12500..12880)
                     /locus_tag="LY912_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBM6955059.1"
                     /translation="MNLTTIHPIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13210..13959
                     /locus_tag="LY912_001352"
     CDS             13210..13959
                     /locus_tag="LY912_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBM6955060.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKLTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14143..15420)
                     /locus_tag="LY912_001353"
     CDS             complement(14143..15420)
                     /locus_tag="LY912_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955061.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15499..16143)
                     /gene="pcp"
                     /locus_tag="LY912_001354"
     CDS             complement(15499..16143)
                     /gene="pcp"
                     /locus_tag="LY912_001354"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBM6955062.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16342..17286)
                     /locus_tag="LY912_001355"
     CDS             complement(16342..17286)
                     /locus_tag="LY912_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBM6955063.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17288..17974)
                     /locus_tag="LY912_001356"
     CDS             complement(17288..17974)
                     /locus_tag="LY912_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBM6955064.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18447..18767
                     /locus_tag="LY912_001357"
     CDS             18447..18767
                     /locus_tag="LY912_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBM6955065.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            18928..19833
                     /locus_tag="LY912_001358"
     CDS             18928..19833
                     /locus_tag="LY912_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6955066.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19830..20603
                     /locus_tag="LY912_001359"
     CDS             19830..20603
                     /locus_tag="LY912_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBM6955067.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(20780..22204)
                     /locus_tag="LY912_001360"
     CDS             complement(20780..22204)
                     /locus_tag="LY912_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6955068.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22415..22861
                     /gene="nrdI"
                     /locus_tag="LY912_001361"
     CDS             22415..22861
                     /gene="nrdI"
                     /locus_tag="LY912_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBM6955069.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            complement(22931..24913)
                     /locus_tag="LY912_001362"
     CDS             complement(22931..24913)
                     /locus_tag="LY912_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBM6955070.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(24927..25823)
                     /gene="murQ"
                     /locus_tag="LY912_001363"
     CDS             complement(24927..25823)
                     /gene="murQ"
                     /locus_tag="LY912_001363"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBM6955071.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            complement(25826..26887)
                     /locus_tag="LY912_001364"
     CDS             complement(25826..26887)
                     /locus_tag="LY912_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBM6955072.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(27099..27665)
                     /locus_tag="LY912_001365"
     CDS             complement(27099..27665)
                     /locus_tag="LY912_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBM6955073.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            complement(27693..29195)
                     /gene="eat(A)"
                     /locus_tag="LY912_001366"
     CDS             complement(27693..29195)
                     /gene="eat(A)"
                     /locus_tag="LY912_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBM6955074.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            complement(29453..30574)
                     /locus_tag="LY912_001367"
     CDS             complement(29453..30574)
                     /locus_tag="LY912_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBM6955075.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            30700..31641
                     /locus_tag="LY912_001368"
     CDS             30700..31641
                     /locus_tag="LY912_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBM6955076.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31784..32680)
                     /locus_tag="LY912_001369"
     CDS             complement(31784..32680)
                     /locus_tag="LY912_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBM6955077.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
BASE COUNT         9539 a         6808 c         5751 g        10684 t
ORIGIN      
        1 aaaaaaacat aaatcagcta ataaatatgt gagacaaagc tgccatccat aaatactagc
       61 tgattttttc agttaaatgt ctattttttt ctctgatgat ggtatttcca aaatattccc
      121 agtcatctgg agtcggtgga tttttccaaa ttatctgttc tttattaaat ttttcaagta
      181 aacaatcaga taaataaata ttcgtacgag aagtgattcg actctcaatc acaatattgt
      241 aatttttaaa tcctttcact tgagaaataa tgtaatcggt ataagcagat ccttgcgaaa
      301 aatcaataca gacatgaatc ggtgcttcaa aatatgatac cggacaaata ccgaccaata
      361 aaaagagata atcataaaat aagcgaatca tgaaacgttc atcttttccc aagaaatagc
      421 gtttattctc ttgtatgacc ttttggattg ctgtactgaa tattggatac gtctcgaaga
      481 aaaactgtag ctgcttttta gacgtaaagc tagtcatctc aaagtcgaat atccaatttt
      541 ttcgattgac atgcatcata cccatacgaa gttcttttcg tatatatagt ctttcttctt
      601 cagagatttc aatcgaaaat ggtaattgat caatcaattc cactgacatt ttttgactaa
      661 tcatgtggat atcatgaaaa tgagcttccg caagtccaaa tgcgccatct aattcaaatt
      721 cttcttccgt gatcaaaaac aacatgatat aagaaatctc atcaatgatc tgctctttag
      781 ggatatgaag aaaagaaata tgtgataaat ccttgatgat cttcattcct tctgagctct
      841 taaagtattc atctgaaaag aaacgttttc cgattggttg attcccatag gccctcaaca
      901 aactaatagt ggttagcaaa ttgaatttga ttcgttttgt tgcagacagt tttaaattga
      961 acagatattc aaaatattgc acgatactct ttgcttcatt catgacgctt tctctaaatg
     1021 gcatagaaaa accattaaag accccgaaat ataccccaaa taatacgttc cgtatgttta
     1081 tttcttcccc aactaatatg tttttcttta actttatttg atgctgttca agaaaagaga
     1141 ctaattctct tctttttaca taggctcttg atatgcttaa aaaatgattc tctgcaaatt
     1201 tttcgatcgt tacttttgaa tccacgatct ccgttaacag tcgagcaatt tttgatcgtt
     1261 gaaagtagat tcttcttaaa tttttgatat ccgtcaaatt cagacgttcg acatggatct
     1321 ctgcttcttc tgaaatttgg atctctggct ttgttttgaa ttcagtaaat tctttattta
     1381 attctatgat ataatttctt gttttaaatt tagacaaacc taatgtttca tataacttag
     1441 gcagcactac ataattcttt ttctcaaatt ctaaatatct agctagcagc agtttttctc
     1501 tatcttcctc ttctataagg taatccaact tcatatccta cacctcaaaa aatgcctcat
     1561 accaattact tgatatgcag atgaaagttc atcttttcac ctatactgat tttatgatgg
     1621 attatgcttg ttttttcatc agttattctc attttttatc ttttttttga gaatattgca
     1681 aaaaatggaa aaatttatga ggaaatattc tatatttttt gttttattgt gttaaaatgt
     1741 acaagatttg cgccatttgc gtaaacaacc acaaaaaaga gcaggacggc caccgtcctg
     1801 ctcttttact tattttaagt tccattactt attaattggc taaacttctg cttgtttctg
     1861 atattgcttg tttttctcca atgatccgca cttctgtttc taaagacaca tcaaattttt
     1921 ctttgattac ttcttggatg tgcgcaatca attcaatata atctgtcgct gtcgcatgat
     1981 cgatattgac gatgaatcca gcatgttttt cagagacttg tgcaccgccc catttcaggc
     2041 cttgcaatcc tgcttgttgg atcagctgac ctgtatagtg tcctactggg cgcttaaaga
     2101 cacttccgca tgaagggtat tctaatggct gttttgattg acgcaattcg gtcaactcat
     2161 ccattcttgc tttgattgct tcataatccc ctgtttgcaa actgaatcga gcttccaata
     2221 cgatagcacg taattcttgg actttactgt gacgataaga aaataccatt tcgtcttttg
     2281 tcaaagtttt caatgttcca tcttcaagca aaagatccac ttcagcaaaa acatctttga
     2341 tctctccgcc atacgcacct gcattcatat aaaccgctcc accgacactt cccgggatgc
     2401 cgcaagcaaa ttcaaatcca gtcaatgatt ctgccaaagc tgcataagtc gtatcaatca
     2461 gtgaggcacc tgcttccgca atgaccatcg ttcctttgac atgaatctgt ttcatttcag
     2521 tcagcatgat gactacaccg cgaatcccgc catcttgaac gatcagattg cttgcatttc
     2581 ctaataccat ccaaggtata tcatggattc ggcaataatc gatgatttgc tttacttctt
     2641 cttgtttttt cgggaatgca aggacatcag ctggtccacc tgttttcgta aacgtatagt
     2701 tcatcaatgg ttcatcaaac aatatagtaa tcgtggctaa gctttcaact atttcttctt
     2761 tattcactga ggattttcct ttcttttctc aaacgtcctc attattctat cacgcttaat
     2821 acaatcttgc cagtcttgtt caaagttgat gacggtagtg atctttaagc acttcctcac
     2881 ataattcatg acttcttaca acttcttttt gtttaagcaa ttctgtttcc gatttaccta
     2941 aacggatctg agaaaagaag gcctctacca ttggctcaaa cccgcgtttg actagcgtgt
     3001 ttgtccagtc gccaaattct ttcacttttt ttccatcagc atcttgaatg acaagctggg
     3061 tcagatcgtt tacttcataa gtaccatttt tacttgttac ttgatatttt tctatattag
     3121 cgccacttgc taaatccatc gttaaaatag ccgtttgatt ttgtgtttct aattgtaaaa
     3181 tggcatattc caaaaattcc tttgtttctc ttatctggta ttttgttctc aaaatgggtt
     3241 catctaataa atacacagct gtatcaataa gatgtaaaaa caaatcataa aggacgaact
     3301 ctgtcgtttc ttttgccgct attcgatttt tttgcaggtg gatcaaccgc ttatctggga
     3361 tacgtttcaa ttcttctacc ataggagcaa agcgccggtt gaaaccgatc atcaaaatta
     3421 tttggttctt atcagctaat tcttgcaatt cacgaacttc atttagatgg acactcagtg
     3481 gtttgtcaat ataaacatgg ataccatttt ctagacattt tttggctaat tcataatgta
     3541 cttttgttgc tgcgtggatc atacatgctt cgattttttc ttctaaaagc tcatcgatcg
     3601 tttcatatag atgttggaac ccgtactctt tttgaattct ttcttttgtt tctttatttc
     3661 ttgttgcaaa ataaaaatca agtgttcctt gttttttcgc ataagttggt aaatatgctt
     3721 tttctgcgat attccctaca ccgattacac caatcttcat ctactttcct cctggatcat
     3781 ttagttactt tcatcttaca ccatttttta ctaaaatgag gtacaatagt atcgcaaagg
     3841 taaggaaatt aattcgaagg agtgtgcttt tattgaaatt tatctcttgg aacgtaaacg
     3901 ggcttcgtgc catcgtaaat aaaaattttt tagaagtttt tcatgagtta gacgccgatt
     3961 ttttctgtct gcaggaaacg aaactccaag caggacaaat tgatttagat cttccaggtt
     4021 attatcaata ttggaattac gcggaacgaa aaggctattc cggcacagcg atttttgcta
     4081 aaaaaccagc attgaatgcc acttacggaa tgggtatcga tatccatgat acagaaggcc
     4141 gtctgattac tttggaatat tccgatttct ttcttgtaac ctgttacacg ccaaattctc
     4201 aaagcgaatt aaaacgttta gattaccgat tagaatggga agaagccttt tataattatt
     4261 tggaaaatct aaaaaaacaa aaaccagtca tcgtgtgtgg ggatctaaat gtcgctcatc
     4321 aaaagattga tttgaaaaac tggaaaacga atcaaaaaaa tgctggattc actccagaag
     4381 aaagagcggc tctttctcga ctgttggata acgggtttat cgatacattc cgttattttt
     4441 atccaaccca ggaaggtgtc tactcttggt ggaactaccg attcaattca aggaaaaaca
     4501 atgctggttg gcggatcgat tactttttga cgagcaaaga tttagagcca ggactagctg
     4561 atgcaaagat ccatacggac attatgggca gtgatcattg tccagtagaa ttagatttga
     4621 aataaagagg ttgtgaaaaa gtcgtttagt ttcgagtatt aagaaaaatt ttgtgaaaat
     4681 ggctttccac attttgcata aatttggcat aataccgaga aactggcttt tgaacactgt
     4741 ttatcgagag attgtgaaaa agctgtcctg catcaagtaa taagaacagc caaacaaaaa
     4801 tagttcctca tatttttcgt ttggttgggc ttattaccgc agatacaagc ttttgaacac
     4861 cgtttattaa gaggttgtga aaaagctgca ctgcatcaag taataagaac agccaaacaa
     4921 aaatagttcc tcatattttt cgtttggttg ggcttattac cgcagatgca agcttttgaa
     4981 caccgtttat taagaggttg tgaaaaagct gcactgcatc aagtaataag aacagccaaa
     5041 caaaaatagt tcctcatatt tttcgtttgg ttggacttat taccgcagat gcaagctttt
     5101 gaacaccgtt tattgagaag ttgtgaaatc agcgtcctga cctgagtatt agagaaacaa
     5161 atggcaaaat agttcctcat attttgctat tttttgagct aataccgagg gtcagctgat
     5221 tgaacaccgt ttagtggaga agttgtgaaa aagtcgccta ctttcgagtc gtaagaaatt
     5281 tttttgaaaa tggttcctca caactttgca taaatttgac ttaataccga gaagtcatga
     5341 tccccatcta actccaaatc acaaggaatg agttcaaaaa ctagcttttc tcaacaaata
     5401 ttacataaaa aattctatgt tttttgttaa atttatttgc ttttttcaaa agtatgttac
     5461 agtaatttcc caaggaggtt ttacagaaat gaattttgtt gccatggatt ttgaaactgc
     5521 caatcatcag ccttatagtg cttgttctct tgcgctagtc atggtaaaaa atagccagat
     5581 cgttgatgaa ttctatacat tgatacagcc tgagactcct tttttctggc gaaatgtcca
     5641 aattcacgga atccatcaag aagacgtacg caatgcgccg aaattcccag aagtctggca
     5701 aactatccaa ccatattttc aaaaaaatcg tttagtcgtt gcacataatg ctgcttttga
     5761 tacaaaggtc ttagcgggat gcttagatta ttatcatctt gaacagccta attatctttc
     5821 tttatgtaca gtgaaaagta gccgtcgcct gtttcctgaa tttccaaatc atcgattgaa
     5881 cactgtgtgc gaaaatttga acatccaatt agatcatcac catgatgcat tggaagatag
     5941 tcgtgcatgt gcggaaatcc tgctttatca agaaaaaaaa ttcgggacag atccattgaa
     6001 aaaacttgtg actataaagt aaaagaatac ttatgaaaca cacaaagagg tcgtgagcct
     6061 gccgtttcac tccgagtcac aaggagcaat ttcaaaaaat agcttctcat gtttattaaa
     6121 tattgtgact ggtgaccgag gagctggcag gagaacaccg tttattggag aggttgtgaa
     6181 aaagctgttc tgcatcaagt aataagaaca gccaaacaaa aatagcttct catatttttc
     6241 atttggttgg acttattacc gcagatgcaa gcttttggac accgtttacc aagaggttgt
     6301 gaaatcagcg ttttgacctg agtattagag aaacaaacgg caaaatagtt cctcatattt
     6361 tgccgttttt tgagctaata ccgaaggtca gctgattgaa caccgtttat tcaaaaaaaa
     6421 tggactgcga cacgactttt gtcacagtcc cttcgtgtgt ttttctgcct tctcaaaagg
     6481 atgacagttt ctcactcttt tcctatttct tctattcaat caaataactc attttatata
     6541 catctaaaaa ttcacctaga tctgttcttg cccctctagg catgaccgct tcgatttgga
     6601 agcccatttt tcggtaaagg tgtacggctc tttcattacg aacttgaacg tcaagctcca
     6661 atcgaaaaag tacacccatt tccttcgccc aactgatgat ttcttctagc ataagagtgc
     6721 ctagtcccat tccccaatat tcctgcagaa tactgatacc gacttctccc acgtgagaca
     6781 aacgaaattg actgtctgcc ttgacagatg ctgttccaat aatcgtccct tcatagattg
     6841 caagcagcaa taaattatta ttgctttcgt atatataatc caactcttct tctaaggttt
     6901 ctggtggtaa caggagttct gcttcatcca aaactaaaaa ttctgtctcc ttattaactt
     6961 gtcccatcat caaaagaatg tcttttgcat ctcctggcac tgcttcccgc aagatgatcc
     7021 caacttcttc actcatgatt ttcagcccat ttttctagaa ttcgctgttt gaaggtttca
     7081 ctttgctccc cgtatgagat tagtttcaca taccgctttt ctaaatctgt atcacttttt
     7141 tctaaaatca gttccaaata atcctccggc agtgcttctt ctaatagatt tccccattca
     7201 acaacggaaa gcccatcacc ttcaaaatat tcatctaacc ctaaatctgc tccgctagct
     7261 gctacccgat aaatatccat atgatacaac ggaatccgac cttgactata ttctctaata
     7321 atcgtgtatg tcggactttt gatcatttgc gttatcccta atccttgggc aattcctttc
     7381 gtcaacgttg ttttacccgc acctagatca ccagtcaata tcagattgtc acctggcatt
     7441 gcggaatgac caattgcctc tgcgaattgt tctgtcattg ttaatcctga tagttcgatc
     7501 atttttcatc ttctcccgct cttctttctt tttgccagta tatcgcgtaa tgaagttttt
     7561 ttaaagaaaa aatgaactag tcaagaacag cagctgctgt ttttggctag ttcgcgtgta
     7621 tttgttaatc aatcaatgtt tgtgctgctg tgataatcga taatttatat acatcttctt
     7681 catttgctcc acgagacaaa tcagaaaccg gtttgttcaa gccttgtaga attggtccga
     7741 ttgcttcaaa gttaccgaaa cgctgagcaa ttttatagcc gatatttcct gactgcaatt
     7801 ctggaaatac aaagactgtt gcttgaccag ctacttctga atctggcgct ttcagttgtg
     7861 caactgaagg aacataagaa gcatcaaatt gcaattcgcc gtcgatcatg tattgtggcg
     7921 ctagtttttt agcgatttta gttgcttcaa ctactttgtc tacttctggc gatttcgctg
     7981 agccttttgt cgagaagctc atcattgcta cttttggttc gatatcgaac aattctgctg
     8041 tttttgcaga atctacggcg atttcagcca attcttgcgc agttggattc acgttgatcg
     8101 cacaatccga aaagacatat ttttcttgat ctcttccacg taccatgatc atcgctccgc
     8161 ttgtccgact gatgccaggc tttgttttga tgatctgaag tgctgggcga acagtgtcgc
     8221 cagtcgaatg gatcgctcca gagaccattc cgtctgcaat ccccatatac gtaagcatcg
     8281 taccaaagta attcacatct tttaaaatct tttctgcttg ttctttggat gcctttccat
     8341 ttctacgttc aacaaaagta tccaccattt catcccactt atcgtaatta tcagggctga
     8401 tgatcgtaaa gctagatgtt ttgattcctc tggcatgcgc tgcatttctt atttcttctt
     8461 cgttccctac taaaatgggt tccacaagtt cttctgcttt caaccgggca gctgcgccta
     8521 aaatacgagc atcagtagct tccgggaaaa cgattttgat cccacggcga acaattttaa
     8581 atcttaaact atcaaacaat tccacaagat gacctccaga cgtttttata tgtattatca
     8641 tacactattc cagaaaaaaa gaacagttta ttttatctgt atcagtcaaa aatgctggaa
     8701 aaattaagtt tttcacatac aaagcgaact gcactataac aggaaagcgc tgttttatta
     8761 cactgtttca ggcagttgcc aatcaatcgg ttcttctcct aacgcaagga gcgcatcatt
     8821 cgttttcgag aagggtttgg aaccaaaaaa gccacgactt gcagataacg gactgggatg
     8881 tggagatgtt atgatgatat ggcgactctt atcgatcatt ttgatttttt cttgtgccgg
     8941 ttttccccac aagataaaca cgattggttt ttcccgttca tttaattttt caatgatcgt
     9001 gtctgttaat ctttcccaac ctttcccgcg atgagaatac gcttgccctt cccgaacggt
     9061 aagaacggtg ttgagtaaaa ggactccctg tttagcccat gacactagat ttccatgttg
     9121 aacaggtgcg attccaagat catcataaag ctctttatag atatttctta acgatggcgg
     9181 gatctttacg ccaggttgca cagaaaaaga taagccatga gcttgatttt ctccatgata
     9241 aggatcttgt cctaaaatca ccactttaac ttcttcataa ggagtcaatt ccaatgcttc
     9301 atagatatga tacatatctg gatggatctt ttgggacgca tattcttttt ttaaaaattc
     9361 tcttagatgc agataataat cttttgaaaa ttctgaggac aaaacttctt gccaactgtt
     9421 atgaatgatt tctttcaaaa actccacctc ctaataaaaa gaataactca cattttcttc
     9481 aatcacaagg gacaatcttc accctcagca cttgattaat atggtaaact aggaacaaga
     9541 agcagaaagg aacgataatc attatgatca aattaattgc atcagatatg gacggcacat
     9601 tattagatgc ccatatgagt gtttctcctg aaaatgccga ggcgatacgt tttgcaaatg
     9661 atgccggtgt tgagttcatg gtcgctactg gtcgaaacta tcaagaagct cgcgcagctt
     9721 tagatgaggt aggaatcgat tgtgcgatga tcactttgaa cggggcacag gtatttgata
     9781 aagaaggaaa ttcattgttt accgtgtcga ttccaaataa tcaagcaatc tctgttttag
     9841 atattctaga tgctaacggt atttactatg aagtagcaac caacgatggt ctttattctg
     9901 aaaatcaagc gaaacgaatt gaaagttttg cttccatggt ggctacccat ttacctcacc
     9961 ttacgtataa aatggcgatt gccatggcct cagctaagct ggagttattg cacatcacat
    10021 acgtggacag tattcgtgct attttggaag aaaagaatct ggaagtttta aaaattattt
    10081 gttttcatac agaagggcca gctgtattag gtccagttgg aaagcagatt tctcttttag
    10141 gcgatctagc cgttacttcc tctggtcaaa acaatatcga agtgaaccat aaaaacgctc
    10201 aaaaaggaat tgctgttgcc catgtcgctc acgagcgtgg gatttcttta gaagaagtca
    10261 tgacgattgg cgataacttc aatgatgtca gcatgctgca agtagcagga gtcagtttcg
    10321 caatgggaaa tgcagaaatc gaagtaaaag attatgccaa atatacaacg gacacaaacc
    10381 ttgaatctgg cgtaggaaaa gccatattgc gcgcgattgc agaagacttg tagttttatc
    10441 tagaaaagag ggatatagat gtcagaattt ttcattcagg aaaagcagct tggacgtgca
    10501 actcggacaa ttgtcaaaaa cgaaaaagga cattccctgt ttttgatggt tggtcgctgg
    10561 ggaacaaagg gcgatgcatt gtctctttat gccatgaatg gcgatctcgt tgctcacatc
    10621 aagcagataa gcctgacatt cggtacgcgt tttgagctgt ataaagagtt cgaaaaggtg
    10681 ggaaccatgc agaaaatatt caattggccc ggtgactttt attatattcg tagacttcac
    10741 tggacagtcc aaggtgatat ctataatcat caatatcaaa tccatcattt caatcagcaa
    10801 atcatgaaaa tggataaagc aacacttttt tcaggagatt actatgtatt ggatgtctca
    10861 aatgatgaag atgctccagt ttgtatttgt attgctgcgg ttttagatta ctggctctac
    10921 cgtaaagaca aaagtcgcga taagcctgtt tcttaccgac ttaacttaag ttaaaaagat
    10981 gtacctgaaa tgcggaaata cgcatttcag gtacatcttt ttagatattc ttttgcatat
    11041 gatcataaag atgaccactg atcatccgct gaccgacaac tttgaagtca tggcgttcgt
    11101 ataatttttt agcctttgga tttttttcat ccacacttag accgatgacg gagcgattag
    11161 ctttcttcgc caatttaggt aatgcttcta ataatcgcga accgatgcct tgtcctctaa
    11221 aatcttctga tacactgata gagtccaaat accattcgtt gggaaacgtt tctttatcaa
    11281 tgaacaaacg tgtagacgca tctagctgat atttctctaa gataggtacc agtggctgat
    11341 cgatgattga ttcttcttca tctgtataac cgtaagcaac tcctgcaact ttaccgtcta
    11401 tttcttctac gatacctcgt gaataactgt aacgataatt tggatcagtg attgcttctt
    11461 ctaaaatctc taaagtcttt tgttcccctg tctgcttcaa aaatggcagt tccatatctt
    11521 ttagaatcac taagatcaat ggggcgattt ctggagcatc ttcttttctc gcaaaacgaa
    11581 tcatagtttc ctctcctttt ctccattcta acatgcagaa aaagaaatcg caaaatcgtt
    11641 attttaaaaa atcttcaatc ttttcagtaa tgaaataacc atgagtaacg attcttgccg
    11701 cttcagttcg gcaataaggg cagacgactg gcatttcttt atcattatgt tcgactacat
    11761 tattgacttc ttcgtatgca aatttttttc cgcaattagg gcatttcatt ttttccatgt
    11821 tatctcaact tcctttcatc tttactctct tagcttactc ttatattgta aaaaagagaa
    11881 gcaatatcct tcttctatgc agatatccat acctgacggt cctgttctcc atctattaat
    11941 cggactttat aataaggacg ttcatctttg actagaagtg tccactcttt cacttttgct
    12001 tttttcccgt agtagctgac tgcttccttc atcgctgctt gcggttgttt gaactcttcc
    12061 gttttttcta tatcaaaaag atgttctgcg gccttttccg tgtcatttcg tacggttgtt
    12121 ttcccagtgg atggattgac tgctatgact tgtccttcac aaaaaaactg gtattcatat
    12181 gttgcattcg taggattctc caaatctttt tcaactgcaa aatgaatagc agatatgtta
    12241 tgttcttttg tttcgttttt tacgattgct gctgcttttt tcaatgagat ccgatattcc
    12301 tggtcactaa tatcatccat gtgaaaagcg gcattgagca gtcccgtcat accggtaatc
    12361 cctattacga tgagggcagc aacaccaaac atcatttttt tcattcttca ttctcctgtt
    12421 tctttttttt aaagaatatc aagaaatgaa cgaatgaaaa atcgaatgaa acgaaaaaaa
    12481 agtgacaatt ttgttatctt tattcgtgca gttctaatgg caatccgtct ggatcaaaga
    12541 aaaacgtcat tttttttcct gtaaaggtat cttctctaat cggttctgat tcgatcccta
    12601 aggactgcaa ttctgcaatt gtttcttcaa tatcgtctac tttgaaagca agatgacgca
    12661 agccacaagc ttctggatag tttggtcgtt gtggcgcatt agcaattcca aaaatctcca
    12721 attcagcact tcctagtttc agatctaatt tatagtcatc tcgttctttg cggtaatttt
    12781 ctctgattac ttcaaatcct aatttattaa cataaaaatc acgtgatttc tgataatctg
    12841 aaacaatgat ggctatagga tggatcgttg taaggttcat atgagcactc ctattcttcg
    12901 tttaagctcg gatctatatt aatctccagt tccattgtaa atgtgtcaga ttgaaaaaaa
    12961 tagctgtttt tcctttttat aagaaaaaag gcaaaaaaaa cagaaagtag gtcctccaag
    13021 acactcttcc tgttcccaat ataataaatg aaagtaagaa attatatttt caagaaaaca
    13081 aacagaaaat tatcataaca caaattattt ataattgaaa gactagtttt ttttcaagaa
    13141 aagcatacaa tagattgtgt tagtaaatac agaacacact acatttagtg tcttaaggag
    13201 tcctcataca tgaagtcata ttttcagttt ttagctcatc agctaaaagg ctggccgcaa
    13261 caaaattatt atcttttctt tttcagtctt ggctgccagg tcatgactct tgtcaatagt
    13321 cccatcactt ggctgtccgt tattacattt atcggtacca cgcttggtgt attgtgtatt
    13381 ttatccatca atgcggcaaa atcagtcaac ggtattttag gtattttgtc tgcgatttgt
    13441 tttattatcg ttgggttttc agcaaagaac tatttaagta tcggtgaaca gattgcttat
    13501 atgatcacat tggatatccc cgtattgtta agtaaagaat ggaatcataa tatggcttca
    13561 aaaatccgaa aattaactgg aaaaagctgg tttatcgcaa tcatcagtac tttccttgtc
    13621 tatcttgttt caggattcct gattggtcgt tatacagatg atcctcggcc gtgggtagat
    13681 gccattgctt tttctattag cttgactgct ggtatcatca gtttcttgcg ttacaacaac
    13741 caatattact ggtggttagc ttcagggctt gctcaaatgg tcctttggta tatttcattt
    13801 acgcatggat ctgcaagttt ggcgatgttc gtgaacagct ctgtttactt gctgaatgat
    13861 gtccttgcat ttaccgtttc accttggtat aaccaaaaag aacgtgaacg tatgcaaaaa
    13921 atggaagaag aatactacaa cgcacaacaa cacgcataaa aaaactgagc gtgggacaaa
    13981 agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaat cagaagcaac
    14041 tccttcggaa ataagctgaa attcacaaaa atttgaaaag caattttcgt gaatttcttc
    14101 ttatttcttg gagttaaacg cttctgtccc agcctctatt ttttatagta attccttcag
    14161 atactttctt gcctcatcat tgaaacgcag tgattcttct aacttctgat aatattccaa
    14221 cgcttgtttc tgagcttcag taaaacgata atgttttcct ttccatttgt cgattgtctc
    14281 ttgcacattt ccagattgga tatctttcac tactagttgc catttttctt ttgagactgt
    14341 acggtctttc ttatcagcag attgtatagc ttctcgttct ttacgcaata cttttaaaaa
    14401 accatttctg actatccgag gaatgctgtc gaagaaccct tctgtaaaac catagcgaca
    14461 atattgcttc caaataaata gatagatttt tggttggatg aatcgttggt ttttcgcaaa
    14521 atattccatc tgagcagtga cttctggtgt tcgttgacgt tttgtctttc tcaacacgga
    14581 aataaatgtt tcaaaataag cattaggatg tactggcact tcttcatata cgatggattg
    14641 ccaatcttta cgtaaaaatg cgcgatagtt gatcaagaat tcttctacat cctttactaa
    14701 ttcttctgca aagtcgtcaa atagttcttt ttttatctgt cgcttttttg actgcccatt
    14761 gatgtgttca cttattttct tgatttcatt ttccaatgct tgataatccg ctatgtaaat
    14821 cggcatttct acttggcgaa attctgcgag ccgctgagct aattttatat ccggtaaata
    14881 tggctgtttc atccgacgat tttggtacaa gacaaaacag tatttttgcc atagtccttc
    14941 aggaaaatcg atattcttct gcttaagcca taataattcg tctaaggcca gatcaacttt
    15001 tgtcattccc tgatggatcg aagctgccac tgtcggagag acatgcaggt gatcggcaaa
    15061 gtggttgatg cctagtttta ggatctttcc ggtttttggc gatttaacga tgtattgcac
    15121 ttttaattct ctaccacact cacaatacaa tttttgctgg cttcgttttg ttcgaaaaaa
    15181 cggattgatc ttgaagtcag aaaacaccca atctgttgca gctaaataat gttcttccat
    15241 aaaacgagag ctgattagat atcggcggtg cttatcgact agttcccgct gttttttcgt
    15301 taattttgca tagatctccc aacgttgact gcttgtgtat tgtttagaaa ttttgatggg
    15361 atagcttttg ctgatttctt ttggaaacca ttcttcaaag acggattgcc attcttccac
    15421 ggctgtttct ttcctttcta attacaaaaa gctggctact aacataacgt tagcaaccag
    15481 ccagtgtttc ttgctaaatt agtgagttgt tccggcattt ccggaaatat cttctttatt
    15541 ttctactgct gcttcaactg cataagtcaa agaagaagca atgtcttcta aagacataga
    15601 aggcgtaccc actggacgat cgatcacttg atcgggtgag aatggcacgt ggatgaaccc
    15661 acctcgaatt gccgggaatt gtgtttcgat caaatgaagc aaacgataca tgatatcatt
    15721 gcagacaaat gttcctgctg tataagagat gtacgctggt agaccatgat cttgtacatt
    15781 ttttgtcatt gctttgattg gcaatgaggt aaagtaagcg gctggaccgt tttcttctaa
    15841 agccgtatcg aatggctgat ttccttcatt atcagggatt cttgcttctg ctagattgat
    15901 tgcgacacgt tcgaacgaga ctgctgaccg cccacctgct tgtccgacac agatcacgac
    15961 atctggttgg tgctgttgga tggcttcttt gactacttga ctgctttttt cgaatacggt
    16021 cggtacttcc actttgatga tttcagcacc gctgatttca tctggcattt tttttactgc
    16081 ttcataggct ggattcactt tgtccccacc aaatggatca aaacctgtta ctagtacttt
    16141 catctgttgt tcctccgtcc gattgattta acatatggtt atcttttatc ataccatttt
    16201 ccttgaacag cgtaaataaa ggaaacaata gtttaaataa cataacagat caaacttaat
    16261 atattcttat aaaaaaatag tgttccacta caatgttaga agaggttgcg acaattattc
    16321 tgtcacaacc cctctcttct attatttaaa tagaatcata taagcaattt ggaaaactag
    16381 cataaataac gcaataaaca actggttttt gatcactccg tatttgtctt tcatctccag
    16441 catcgctaca ggcacgatat tgaagttagc agccatcggt gtcagcaggg tcccacaaaa
    16501 accgcaagtc aatgcaacca ttcctattaa cgctggattc gctccatgac taaatacgaa
    16561 tggtgcaccg atcccaaccg tcatcacggt gatggccgca aatgcattcc ccatgattac
    16621 cgtaaatatc accatgccaa gagcgtaaat gatgatgccg atgttcacat ttccttctgg
    16681 aacgatcgta cctactgcat tggaaatcac tgtcccaact ccagcgcttg taaataccgc
    16741 acctagagaa gctaaaagca ttggcaacat gcttaacggc cctactgtgc ccagcatatc
    16801 tgctgcatca tctaaaaatg tacttggtcg attatctcga gaaaagaaca tcaagattag
    16861 catggctgca aaaacaccga cgcccacgcc gactaaagca cctaaattgg taaatagagc
    16921 aaacaagatc gcaaagacac cgatactcaa agctggaata aaaattttca ttcctagttt
    16981 gtctgacatt ttttccatat attcttttga tggaagccgg ctttctcctt tgctgacttt
    17041 cttagcaatt gctggtatgg tcatcgcaaa gatcaagcca ccgttcacga ttgccggaag
    17101 ccatcttcct cctgcaataa ctacccctaa gaccgtccag aaaaaggctg acccataacg
    17161 atgaggattg gttttatctg ttaaatttct tactccagtg taaatcaata cgagtcccat
    17221 cacgatataa aggatctcca gtaatttatc gcctaataaa atatcaggat ttgtaaaaaa
    17281 gtccatctta ttgccccttt cctggataat atttcttcgc taatttcttt tctttaagat
    17341 agaagtagac acttgccaca actaaagccg tgatagccac tggaacttcc actaaagcaa
    17401 gctgtcccaa tgttacgtca tatcctagat ctttcagtgt tgattggact agcaacgccc
    17461 ctgctcctcc gatgaatagt acttggccaa agaaccagca gacattttcc atagctgaag
    17521 ccataccttt tagttcttct tcatgcttag gatggacttc taaccctttt gattcgatgg
    17581 tccccaatgc catcggtaaa atgattggac gaacaaatcc agcaactcca ccaaaactca
    17641 cgttaaaagc cgcaaagatc attcgaaaga tcccataaat atctacaatc ataccagcag
    17701 atactttctt gaatcgcttg atcaaggaag ccgctgattc tttcagacca tttctttcaa
    17761 gcgttcctgt tgccaacata atgatgataa aaatcgccat cccgcgattg tttacaaaac
    17821 ttgtacctaa aagttctaac attccttgaa tgccaagacc gccagtcaaa gctgtaacaa
    17881 ctaaagcaac cattacgatc aatatcgagt ctaatttaaa tgcaaacccg agaataacaa
    17941 tcaagacgcc taaaaggcta agataatttt ccatatattt tcctccataa aatgacaata
    18001 tttttttaat tataaagcaa aacacataaa aaatatagtt gttttctcac gaaatagaca
    18061 ctatttttaa atatttttcg ttattttttt attatataat tcaccttact tattgtaaga
    18121 taaagctttt tttaatttat tgcctgctaa tatataaaaa taaggtctag ttactgtttt
    18181 tttaaatgat taataaataa caactccttt ctatgaaatt gcaaagcatt catcttcttt
    18241 tctgctaacg atatatccgt caatgcttgt tacactttac taaaaagtat gagattgccg
    18301 atatctggat aggtgtgcta tactacagaa aaagatatac gatctgccac cgggtagtaa
    18361 aaaagaggat gatcattcca ttaggtcttt gaagggatga ttctcctctt tttgtgtatt
    18421 ttttatattg aaggaggaac gtatgtatgg catggatgga attaatcata gcaggaattt
    18481 tggaagtatt ctggtcaacg atgatgaaat ggagtgatgg tttttctaaa atcaattatt
    18541 ctttttacac agtgattgga atgattgcta gtttttactt tttgtcaaag gcaatcaaaa
    18601 gtttgcctat gagtctctct tatcctattt ggacagggat tggcgcagtt ggttcggtca
    18661 ttattggtgt ggtcttgttt catgataagc tgaatctttc cacttggttc tttgtcgggt
    18721 tgctgctcat cagcatcatt ggcatcaaaa tcactagcgg tcactagata cttagacaag
    18781 cagacaagga ctgatcagaa aaagcggggc tttttatttg atattcctct ttctatgaaa
    18841 aaacaagaaa ataagactaa tgacctagcg acttctctac tcatcaggtg tatgcttgta
    18901 ctatctatag aaaaggagtg aatatttttg aaaagtcttt cggtccaaga attatccaag
    18961 aactttggtc acaaacaagc cctcagcgat gtcagtttta gcttatctcc tggcaaaatc
    19021 gttggattag taggtcctaa tggcgctgga aaaacaacga tcatgaaagc tattttagga
    19081 ctgatccatt actcagaagg aacgatccgt attggtgaaa atgagatttc tccctctagt
    19141 cataaaggat tagaacaagt aggagcattg atcgaatatc cgggtatcta tccattctta
    19201 acaggttatg atcatctgaa gttattctct gaaacaaacg atgtatctgc tatcgacact
    19261 atcgtgaaac agctcaagat ggaaaaatac attcacaaaa aagcgaaatc ctactcgctg
    19321 ggaatgaaac aaaaattggg aattgctctt gccttactga accatccgtc tatcgttatt
    19381 ttagatgagc cgatgaacgg tttggatcca caagcaacaa gagatgtgcg aaaaatcatt
    19441 accgacttgg ctactcaggg cacctctttc ttgatctcca gtcacttact cagcgagctt
    19501 gaaaaaatgg tcgatgagct gatcctgatc aatcaaggaa aaatcatcaa acaatgtaca
    19561 atggctgaat tgaaccaaac agcgcaagat ttcatcgtta tctctacgac aaatgatcaa
    19621 gctgctcgaa cgatcttgac agacgctgga tatcccttgg aagatcctga taaaatcaag
    19681 cttctaaaaa aaaacgaaga gttattagga actgttatcc agttattgtc tgcagaaaat
    19741 gtccatgtga cagatgtcca gcatctgacg aatgatttgg aatcttccct attggaaatt
    19801 ctggattcag taaaggggga agaagaaaaa tgacgttgct tataaaacaa gaattattta
    19861 aattgatcaa gaaaaagtca actgctgttt tatctgttct attagttgct ttgctcatag
    19921 gaacagcact tctagccaaa aaatacacga cgatcattga tccagttgaa atgactgctc
    19981 agcttttcag tgccacatct tggattgtct ttatcatgat tgctgctgca agtacgatca
    20041 tttcaatgga atcacaatat ggtacattga aaaatctcct ttatcgaaag tattctcgag
    20101 gagaaatatt agtaagtaaa tggatcacat tagttattta ttctatttat ttataccttt
    20161 tagctattat tgtcaccgtg ctgatgaaac tgatcctttt cccttcgatt tcctttacgg
    20221 agaagatttc tactggtcag acactgatcc aaagcttatt cacttatact ttgggtagtt
    20281 atatcggttt atggctaatt ttaagtttag tgttgatgat tgcttgtttt atcaatagtt
    20341 ccggtgcctc catctcagca gggatcgtct tttattttgc ttcatcaatc atatctggta
    20401 tcctcatcgc actcattcaa aaatgggagt ggatcaaatg gaatccaatc agtatgctga
    20461 atctgcaaaa ccaaattggc aacgaagaga ttatgaagca attgactcat ctttctacta
    20521 atcaaatgct gtttggcaat ttagcttaca ttgctttgtt cttagcattg ggatacctcg
    20581 tattcaagcg aaaaaatgta tgatggttca ttaacaaaga agttgtgaca gaagtggcca
    20641 gtttcaagaa atttcggctt atttttagaa gaagctactt cttgaacacc atttattcaa
    20701 aaaaagaagc gatgacacga atgttgtcac cgcttctttt ttgaataaac cacaggcttc
    20761 acagcctctc tttatacttc tatacgtgaa gcatcccagt ggcaaataaa accattgcga
    20821 ttactccgac catcgtcaca ccgataagta aaatcttatc taagtggata tgttgtacag
    20881 gttcgttttg ttctttacgt gctttgaggt aaaaataaat acctggtaag aaaagaacaa
    20941 gaacaagcat cacttcatta aaggctacaa ctagcatggc ccatacttga aaagcacttg
    21001 ctaaaaaccc tactaaaaat tggacccact ctttccgctg ataagaaagc ttcatttggt
    21061 acagccctaa gaaaagccac gtgaagaaaa tcgctgctgt accaagtgta taagcaaagt
    21121 tatatgcact gtcagtgaat aataatgaaa gtaaaaagac attcgtacat aacgtcgtca
    21181 atacgatagc ataagttggt gccccatttt tgttgagttt tccccatgct ttaggcaaaa
    21241 gtccgtcctc agccatattc cccattgttt caatcggcaa gattgtccat gagagccaaa
    21301 ccccaactaa agaaatgatc aaaccgccgt tgatcacgac cgccccccat ttaccaacca
    21361 tcatttcaaa tacatatccc atagcaggtt gcgctttgat cgtttgcagc tgattcatcg
    21421 tcattgtgcc atatggaagc atggaaacca agacgtaaat aatgatcaaa ccgaatattc
    21481 ctagaatcgt tgctttccca acatccgatt gtttttttgc tcgtgaacct acgacagaag
    21541 ctccttcaat accaacgaat acccagagca tcaccatgat gcaactcaat acttgactag
    21601 aaaacgggat cggctgccca ttcgcattca atatgatatc gctagaaaag ttattaatga
    21661 attgttggat cgaaaaggtg ctgatagcta ctacaataaa taaaaataat ggcactaatt
    21721 tacaaaatgt gacgatagca ttgacaaagc tagcattttc aactccacga ttcactagcc
    21781 atgcatatcc ccataagaag atcgtactca tcacgatcga tgccacattt tgaccacctt
    21841 cgaatacggg gaagaaataa cctaatgcac tcatcaacaa tgttgcgaac gccacgtttc
    21901 ctaaccagca tgtgagccag taaccccaac cgctgataaa accagcgaaa cggccaaaac
    21961 cttcttctgc gtaactaaag atcccgcctt ttaaatctgg acgtttttta ttgatattat
    22021 tgatcgataa ggagagcatc aacattgctg ttcctacgag tacccagctg aagatagctg
    22081 ggccaccagc cgatccggag atgtccgtca taataccaaa tacgccacct ccaatcgctg
    22141 aaccaatcac taaggcagca agtggaatca aaccaattcc ttttttctgt tgctctgtat
    22201 ccatgtaagc atcctccaaa gtaaaaccgc ttttatcaaa aagtataaca aacctttttt
    22261 atttttactt aattaataaa aactttaata gaaatataat tctaccgact tttttctcat
    22321 tatacaagca aagcgcctag tccctttcca aattacacca ccaaaaaaac ttaaaaagat
    22381 gctatactaa agggaaagaa ttgggggatg atccatgaac attttatata tatcgatttc
    22441 aggaaatacg cgtgcttttg ccaaacatct agcagaatat gctgaaaaaa tgcatgcaga
    22501 agatcctgtc aatcctgaag ttactttaaa agaaatccat gaaaatagtg attttacgaa
    22561 agaaacagaa ccatttttta ctttcgttcc tacttattta gacggcggga atgggttaga
    22621 caacggtgac acagaaatct tgaccgaaac gatgcgcgaa tatctggaat acgaagacaa
    22681 tcataaactt tgccttggtg tagtcggtag cggtaataaa aacttcaaca atcaatattg
    22741 tctgacagcc aaacaatacg cacaaagatt cggctttcct ttcttggcag attatgaatt
    22801 acggggaaca ccatctgatg tgacacgcgt ttatcaaatt ttggcagaaa aaaataaata
    22861 acacaaaaga agaagctgaa aaataaattt cggcttcttc tttttatgtt ctctattgtt
    22921 tctattctta ttaagctttg acatccatca caggtgcttt tgctttcgct ttacctgttt
    22981 tttccaagac aaagtttttt acacgatcca tattggttac caagacgatc atggaggttt
    23041 ctttgtctgc tgctttgatt gcttctaagt cagcttctgc tacaagcgta tcaggtgtca
    23101 cttgctgtcc ttctgttact ttcacatcga atggcgtacc gcctaagtca actgtgttga
    23161 tgcccatgtg aagcaagatt tctaagccat ttggtgtcgt aatgccgata gcatgttttg
    23221 ttgggaaaac agaacttatt actccagtaa ccggggaata gatatgtccg ttttctggtt
    23281 ctacaaagta accttcaccc atcatttttt gtgcaaaaac tgggtcactt gctttatcta
    23341 aagaaacaac tgttccgtca gcaactgatg ataagatagt cacactttca gctgaagctt
    23401 gaggtactgc tttttcaggt acttcattta ctgtggctgt ttcggtcgct agttcttctt
    23461 tttctaaacg gtctttagga ataccgaaga agaatgtagc aacgaagcca ccagcgtaag
    23521 cagccaataa accaaggata tagcctaacc atttaccatc agagatcaat ggaatcaaag
    23581 cggctcctga aggtccaata gcgattgctc cgacatttcc gatcattccg atcactgccc
    23641 caccgatacc tccaccgata caagcagtaa taaatggacg tcctagaggt aatgttactc
    23701 cgtaaatcaa tggttcgccg attcctaaga ttccgactgg taaagcccct ttgatcattt
    23761 ctgttaattc tttgtctttt ttgcagcgga tccataatgc caatgctgca cccacttgtc
    23821 ctgctccggc catcgcaagg attggaagca ataaggtacg accagtttca tcaatcattt
    23881 gtacatggat tggcgtcaag atctgatgta gtccgaacat gaccattggc aagaataatg
    23941 tacctagaac gaagccggca aatgctcctc caacaccaag tacccagttg atcccaccga
    24001 ccatgccgtc agaaatgaac cctgctaaag gcatgatgaa gaaaatttcg atcagaccga
    24061 tggcaatcag ggaaagagtt ggcgtaacga tgatatctac cgcatcaggt actactttat
    24121 gcagtttttt ctcaacgatt gacaataacc aaactgcgaa gataacacct aagatcccgc
    24181 cttgtccagt tgcaagagct tcaccggtaa acaagttttt cagtggtgct tctggattca
    24241 tccctgtcag catcacaaca gccccgataa ctccaccaag cgttggcgtt gcaccaaaaa
    24301 cttgtgcagc attgatacct gtatagataa ctagatagct aaacatcccg tttttcaaga
    24361 tgttcatcac atcgatatat tgttgccatg ttcctgcgtc tagtgttcca gctgtgacta
    24421 agtttgctaa aactgcggca atccctgcca cgatcccagt gccgacaaat gcagggatca
    24481 ttggtacaaa gatattagag atgtctttta ataccgattt gattttagag ggtttttgtt
    24541 tcgatttttg tgccgctttc atttcttgtg cccgttcgtt tacacggtct tttccagatg
    24601 cagaagaact tgctgtagtt gcactagcag aaggaagttt ttctcctaat ttcacgcctg
    24661 ctaagtcaac catttcctgc gctactttgt tcactttccc aggtccgatg atgacttgga
    24721 gctgttcatc ctctactacg ccaagtactc ctggaatcgc ttttaattcc gagacattta
    24781 caagatcatc attgatgacc ttcatacgta cacgagtcat gcagtggaca atgctttcaa
    24841 cattgcccat accgcctgct ccttgataaa tttgttttgc cagttcttcc aaagtcaatt
    24901 cgttttttgc catggtcttt tccccctcat aaggttcctt ttacaaaacc gtttgcttca
    24961 gctaattttg cttgagctgc ctctttatca ctatttgtca aaatcatgac gatagccagt
    25021 ttgacatttt gatctgcttc ctcaaagtac ttttcagctg tttcgtagtc agcttctgtc
    25081 gcttgcatga tgattcgttt tgagcgttca attagttttt catttgttgg tttgacgtcg
    25141 accatcaagt tattgaatac tttaccgata ccgatcatac tgatagtaga aatcatattc
    25201 aaaatcagtt tttgtgctgt tcctgacttc aatcgagtag agcctgtcaa aaattctggt
    25261 cctgcatcga cttcgattgg gaaatccgca tgctcgctga tttctgcttg tttattgcaa
    25321 gaaatcgttc ctgtaacagc accaatcgat tttgcgtaat ctaatccacc aatcacatat
    25381 ggtgtacgac cgctagctgc gataccaata actatatcat tttttgttaa attcagcttg
    25441 attagatctt cttgccctaa ttcataagaa tcttcggctc cttcgacggc tacagtcatt
    25501 gcttcttctc caccagcaat taggcctatg accatttccg gttctacacc gaatgtcggt
    25561 acacattcag cagcatctaa tacaccaagt ctaccactcg ttccagctcc catataaatc
    25621 aagcgaccac cttttttaaa ggattcaatc gtgttggcga tcactggctc gatacttggc
    25681 agttcttttt caacagcagc ggccactttc tgatcttctt tgttcatgag ttggactgct
    25741 tgagaaatac tcatttcatc taatccaaaa gtttcttggt ttctgcgttc cgttgttagg
    25801 ttctctaaat tgattttgct catttttatc ttccttcttt tcttataaat tgatagttca
    25861 taccagcttt gatttggttg atcagcggta gttcttcttt gatgactttg gctactacat
    25921 tcactttttc atccgctggc aaatcatatt tagttaattg gatctcaccc atatagcgca
    25981 aatacttttc gttatctaaa gtaatagatc ctttcatacg cttagctgta tttcttactg
    26041 ggattggcgg aatctctcga aaacgcgcat ctgcgcttcg tatgacatct cttgcatcat
    26101 cttgccgatt cgtatgtttt cctaatatat attcgtaaaa aacttcatct acaggttccg
    26161 tatggagcaa gactgtctgt tctttttgga aagaagcaaa ttgctcctga acgtgttctg
    26221 acagacctgc atctccgata taaacaatat ccgtgttact tgctaataga tcaagagcac
    26281 ctgccagagg atggatccct cgatgttctt ccaaagttgg taatccttga tacagtggac
    26341 ctctcaactc tgtatctcct ggtacaaagc cttgtacaag gaatccttga gttttgagcc
    26401 attgattttt ttcctgatac cattctttgt ccaaccctgt ttcaagacgt ggataataat
    26461 tatgccaagc ttcaatctgt gagaaatcag ccgctgcttc tttcaactca tcgatatcat
    26521 taggcgtgat cgtgctggca ttcaaactga ttttcaattg atgtgaccag tcggcgatct
    26581 gctgattaga aatatgataa tccattctta accctgttac accaattgct ttcaagggtg
    26641 ttagatcttc taatgaaaag ccagctcgtt tcaatgcctc tcctgaaata tcgaccatca
    26701 actctagttt attctttttc gcttcgcttc ctagttcgat caatcgattt tgataagccg
    26761 aaacatcatc ttccggtata tgcatggaag tgaaaatacc gacaaagcca ttggatgcca
    26821 tttggcggat atactgtttc ttctcttctg acaaagaatc attcataaat attgaaaagc
    26881 caaacatatt atccctcttt ttctgtatcc gtcttcattt ctatgactag agtatatatc
    26941 taaagaaaca aaatttcaat acttttgtta aaataattaa attttatttc taaaaattgg
    27001 atttataatg ccaaaagaat tgacacagcc acaaaaaagg cactgctaag caaaagcagt
    27061 gccttgaaac attttattta aataacacaa aagtctaatt actcataaga aattaattct
    27121 gtattgtcta ccatgaatgt aaagaaccct tcattaggca ttggatgaaa ataagcattg
    27181 atcactctta tcaaggcatt atgacagact aacaagtaga cattttcttc gtcttccatg
    27241 cattctttca ataaaggaac gatccgtgcg tacacatcta agaccgactc tccatttggg
    27301 aaacgtacag caaacgctaa acgcgctttt tgaaagtttt catctttgct tggcagtccg
    27361 tcataatccc caaaatccat ttctaccaat cgctcatcag cggtcatcgg caaattgaga
    27421 cgatcaacta ctgcttgtgc tgtatctctt gctcgttgaa gaggggaatg gatgattttc
    27481 gtgattggaa caggcaaatc tactaccttt tctgctagtg cctgtgcctg catctgtcct
    27541 ttttcagtca gcggcacatc tgctcgcccg caaactaatc cttgtgcgtt ccaagttgtt
    27601 tctccgtgtc tcgttacata aagcatgtga ttctctcctt cgttgacaaa gttctcctta
    27661 accatacctt gttgtctttg agattacaag gtttagattt tctcaagaga aataatctca
    27721 gtagatactt tatctagaaa ggtttgatca tgttccacta gtaacatagc aggtttcacg
    27781 ttcaaaatca gttgttctaa ttgttcttga ttgaagacat ccaaataatt caatggttca
    27841 tcccatatat agagctcagc tggttgggat aaagatttag ccaattccac ttttttccgt
    27901 tgtcccatac tcatctgttc gattttatta tgaaaaacat ctctttccat cccaagcttt
    27961 cggagattat tcaaaaatgc ttgatagtct actcggtttt tcttcgcgaa ttccgccaat
    28021 gtccctcgat tgtcttcata attttggcgt acgtaactaa tggtcaaatg tttgggctgg
    28081 gatttttctc ctacaacctt gccgttgaat gtccccagaa gataatggat aatggatgac
    28141 tttcccgcgc cgttaggacc tgaaattgcc atccgctgat gaggttcgat cgtaaaatga
    28201 actggctcga ataacagatt ttcataccct aattgaagat tttctacgct taacagccgt
    28261 ttatgatgag acacttggct attcatcgtc aaagcatcga tatactcgat atcttttaat
    28321 aatttttctt tctcactgat ctgggtttcc atccgattca cgattgcttt agatcgtttc
    28381 atcgtccgtg cagcatcagc gcctactgct cctttattca ctcgcctaga ttccgtatcg
    28441 atgaatccga cttttttctt tgttttgtcc ccttctcggg aacgagacca ttctgctttt
    28501 tcagctgctg ttttctttag cctgctgact tcttttttca atttttcatt tttagctatt
    28561 tcaaattcat cacgaagttt tttctgttct tcatagatag agaaattccc ttgataaagt
    28621 tccagttggc tcttttcgat tgctaaaaca tggtccacta cttcatcgat aaatccccga
    28681 tcatgactca ccacgatgaa tccttgtttt ttctttttca agtaagccgc tacttgtttt
    28741 ctgccagaga tatccaaatg attcgttggt tcatcgatta acgggaaatg agtgtcatcc
    28801 acaaataaga gtgccagtag gacttttgtc ttctctcctc ctgatagtgt gctgaattct
    28861 ctccataaga tttcaggatc tgtttgcatc agttggagct ctctttcaat ttcccatatc
    28921 tcaaaatcca taatctcatt taacacataa taggtcaaac gctctttatc ttttgtttgc
    28981 tgcgggaaat agacaaacgc ttgctgatgg atcacttgcc cttgataagg gagtttgttt
    29041 tgcaggatat tcagtaaagt tgtctttcct cgaccgtttc gtccgataag tcctagtttc
    29101 cattgtgtgt caaagtttag attggcttgt tcaaataata atgtgccttg gctgtcatag
    29161 ccgaatgtca gattttttat ttcgatttta gacattattc catcacctcg taaaaaaaga
    29221 ccagtcctat tttcagaact ggctaaagag gatgcaaggg ttggggcaca caaaaagacc
    29281 catacatcga aagaaccaag ccaatcccga aaatctgcac actgctccct tgtctccaca
    29341 aggtacagtc tgaatgcagc tttcatcaat cgacttaatt tttcaatgca cggatccctc
    29401 actttgtcct atatttgaaa ttacgatagc ataaagaaat tgtttttgtc aactacttcg
    29461 ggagaatgtt gaaaaatctg ctgagtgtct gtcctaagat ttctgttttt tctaatgttt
    29521 gcctgtgttc cattgcttcc tctaaatcga ttggtcctaa ttgaatgctt aagacaatgg
    29581 ggagaaaatc aaagagtcct tccagctctc ggtctctact tccgcaaata gcgattattg
    29641 gttttcgata tttttttgca agcactgcta cgccatatgg aacttttccg tggattgttt
    29701 gctgatcaat ccgcccttct cctgtaatga tgacatccgc ttgttcgatc tgtttttcta
    29761 atccagtgat ttggctgacc aactcaaaac cagagaccat cttcgctcct aacaaaaaaa
    29821 gggctccgcc aataccgcct gctgctccgc ttcctgggat gtcatctaaa tccacctccc
    29881 aaacatcttt tatctgctga gcaatctttt cagcttgttt atccaagaaa gctaacgtcg
    29941 tatccgttcc tcctttttgt cttccaaatt gccaagcagc tccttgttga cctgtatatg
    30001 ggttggtcac gtctgcagcg atgatcactt ttactttaga aacaagaacg ttccttcgat
    30061 ccaaatgaag ttttctagta gataacaaag gatttccttc tgtgtaccct tctaaagaag
    30121 cacccaaaga ttggagtaat cctagaccac catcgctaca tccgcttcct cctaaagtga
    30181 caatgatttg ttccacttct tgaagcagtg tatctttgat aagctctccc aaggcataac
    30241 tagaagcaag tcggatggtt tgatccgttg gtttatcaag taaatctaat cctaatactt
    30301 gtgcagattc aatgactgcg gtattttttc cttgccagtt cgtcaataaa taactgattt
    30361 ttcgctgacg aaataagaga tccatcccat caatcgtacg ccaggttccc ccgagcgcgt
    30421 aatagattgc ttctgcagta ttttctccgc catctgcaat cggcacattg atttttcttc
    30481 ctttacggtc ttcccaacca tttagaactg cctgatttaa ttcaaatgaa gaagcacttc
    30541 ctttaaatga atcgattgcc gccaaaatat ccatctatat ccctcacttt cttcttaagt
    30601 aagacacttt ttttcacttt tttcaaacaa aacaatgcta ttttcttctg tttttctata
    30661 tactaaaagg gaactcattg aataaaggag agaaaaaaca tgaaaatcgc aatagctgga
    30721 gccggagcaa tgggcagccg aatcggatta atgttgcatc aaagcggaaa tgaggtcgtc
    30781 ttgatcgatc gctggcctgc tcacattgaa gccattcgta caaatggatt gattgctgac
    30841 tttaatggca aagaagtagt tgcaaaactg ccaatctatt caccagaaga aatcatcgaa
    30901 agcaacaaac acgtggattt gatcgtagcc ttgacaaaag cgaatcaatt agatgatatg
    30961 tttcgttcga tccaatccat tattactgag aatacttatg ttttgtgttt actgaatgga
    31021 ttaggtcatg aagatgtact ggaaaaatat gtaccaaaga aaaatatctt atttgggatc
    31081 acgatgtgga cagctggtct agctggtccc ggaaaagtca cattattagg tgatggagaa
    31141 atcgaactag agaacttgga accagaaggc gaagcattta caaaaaaagt tgtagaagtc
    31201 tttcaagaag caaaattgaa tccaatctat agtcataatg ttcgttattc catttggcga
    31261 aaagcttgtg taaacggaac attaaatgga ttatgcacga tattggattg taatattgct
    31321 gaattaggtg cgcaaaaagc ggcagagggc atggttcgaa cgattgtatc tgagtttgct
    31381 tctatcgcag caaaagaagg aatcacatta gatcaagaag aagtgtacca acatattgct
    31441 tctacttatg atcctgacaa catcgggttg cattacccat ctatgtacca agacctgatc
    31501 aaaaaccatc gtttgactga aatcgactac atcaatggtg ccgtttggcg aaaaggacaa
    31561 aaatatgata ttgctacacc atattgtgcc tttttgaccc aattagtcca tgcaaaagaa
    31621 ggaatccttg gcgcagaata aaaggctctc tgatgagaat cagctggatc agcagctggt
    31681 tctcattttt ttacccccat gaaagttcaa aaagaaaaac acaattctca tgttgccata
    31741 agaattgcgc ttgtttattt tcatctatga ttggttggca cttttattta tttttaacag
    31801 aggaaagatc gtattcatat tgttcataaa tagcggagtc agtagtgaaa aaacgttttg
    31861 cccaattttc tgcatcaaaa aattccaaca gttctgatgg gattggttga aatggcgtat
    31921 gcaaaaattc cggtaattca tctaaatcac gttcttgaag caaaaaaata ttttcagaat
    31981 gataaaactg ataatgagct atggcttgat tatctgtcac tagtttcttt tgaaaataca
    32041 tagattcaaa cgttcgcaaa gtcactcctt gctgcccttc ccgcaacagt tctagaatcc
    32101 ccctcgattc cccggttttt ttcagatatt cttcataagt aaggtatcca ggttgttcat
    32161 ttcctcgaag cggaagaata aagtaattgg tcgtaacacc tctttttgta aattcctgct
    32221 tatatttttc tgcccgttct tttctgccgt tatttgttgc accaaaaaat agatccgtct
    32281 ttggttcgct agaagaaaaa tccatatgtt tcgaataaaa ggaactatta tgttttagtc
    32341 caagttcttt cgcttctaaa aaatcaaaat gataaatctc atcgattgcc ggttcatctt
    32401 gtgcctgctt cagcatcgcc tcgtgttctg ctttaaagtg gttccaaaaa aataacacga
    32461 tttttgcatt ggtaaatgga cgcacgcgtc gagccatctc catatcaaat ccataatcta
    32521 aaaaaacgat cagctgataa tttgccaact gttgtcgagc tgatttaatg aattccgact
    32581 gtagtaaatc ttttccggac caaacatcta aagagcggat ggaaggaaaa aaataaagtg
    32641 atttattttt cgcaattagc aatacgtcgt ttttgttcat ctgttccgcc tcactttctc
    32701 tgtcactttt tcctatgata gcctgtttaa atagtaaaaa gccagtaaaa cgcttcctat
    32761 tatttttata aaaatttaac at
//
LOCUS       DAFKHN010000031        32535 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFKHN010000031 DAFKHN010000000
VERSION     DAFKHN010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.031"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            133..507
                     /locus_tag="LY912_001370"
     CDS             133..507
                     /locus_tag="LY912_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBM6955078.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="LY912_001371"
     CDS             complement(621..1250)
                     /locus_tag="LY912_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBM6955079.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="LY912_001372"
     tRNA            complement(1384..1456)
                     /locus_tag="LY912_001372"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="LY912_001373"
     tRNA            1670..1743
                     /locus_tag="LY912_001373"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
     gene            complement(1881..2045)
                     /locus_tag="LY912_001374"
     CDS             complement(1881..2045)
                     /locus_tag="LY912_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955080.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2340..3668
                     /locus_tag="LY912_001375"
     CDS             2340..3668
                     /locus_tag="LY912_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBM6955081.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3870..4703
                     /locus_tag="LY912_001376"
     CDS             3870..4703
                     /locus_tag="LY912_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBM6955082.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4719..5456
                     /locus_tag="LY912_001377"
     CDS             4719..5456
                     /locus_tag="LY912_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBM6955083.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5611..6579)
                     /locus_tag="LY912_001378"
     CDS             complement(5611..6579)
                     /locus_tag="LY912_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBM6955084.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6811..7644
                     /locus_tag="LY912_001379"
     CDS             6811..7644
                     /locus_tag="LY912_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBM6955085.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7678..8517
                     /locus_tag="LY912_001380"
     CDS             7678..8517
                     /locus_tag="LY912_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBM6955086.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8543..9103
                     /locus_tag="LY912_001381"
     CDS             8543..9103
                     /locus_tag="LY912_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBM6955087.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9302..11023
                     /locus_tag="LY912_001382"
     CDS             9302..11023
                     /locus_tag="LY912_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBM6955088.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11188..12330
                     /locus_tag="LY912_001383"
     CDS             11188..12330
                     /locus_tag="LY912_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBM6955089.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12346..13557
                     /gene="thiI"
                     /locus_tag="LY912_001384"
     CDS             12346..13557
                     /gene="thiI"
                     /locus_tag="LY912_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBM6955090.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14130..14777
                     /locus_tag="LY912_001385"
     CDS             14130..14777
                     /locus_tag="LY912_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBM6955091.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="LY912_001386"
     CDS             15170..17815
                     /locus_tag="LY912_001386"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBM6955092.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="LY912_001387"
     CDS             18125..19438
                     /locus_tag="LY912_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBM6955093.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="LY912_001388"
     CDS             19428..20081
                     /locus_tag="LY912_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBM6955094.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="LY912_001389"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="LY912_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBM6955095.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="LY912_001390"
     CDS             20978..21178
                     /locus_tag="LY912_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBM6955096.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21432..23111)
                     /locus_tag="LY912_001391"
     CDS             complement(21432..23111)
                     /locus_tag="LY912_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBM6955097.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23113..23325)
                     /locus_tag="LY912_001392"
     CDS             complement(23113..23325)
                     /locus_tag="LY912_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBM6955098.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23718..25448
                     /gene="efrA"
                     /locus_tag="LY912_001393"
     CDS             23718..25448
                     /gene="efrA"
                     /locus_tag="LY912_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBM6955099.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25445..27205
                     /gene="efrB"
                     /locus_tag="LY912_001394"
     CDS             25445..27205
                     /gene="efrB"
                     /locus_tag="LY912_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBM6955100.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27300..27497
                     /locus_tag="LY912_001395"
     CDS             27300..27497
                     /locus_tag="LY912_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955101.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27650..28135
                     /locus_tag="LY912_001396"
     CDS             27650..28135
                     /locus_tag="LY912_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBM6955102.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="LY912_001397"
     CDS             complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="LY912_001397"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBM6955103.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29012..29533
                     /locus_tag="LY912_001398"
     CDS             29012..29533
                     /locus_tag="LY912_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955104.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDV"
     gene            29630..30367
                     /locus_tag="LY912_001399"
     CDS             29630..30367
                     /locus_tag="LY912_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBM6955105.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30371..31288
                     /gene="miaA"
                     /locus_tag="LY912_001400"
     CDS             30371..31288
                     /gene="miaA"
                     /locus_tag="LY912_001400"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBM6955106.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31290..32519
                     /gene="hflX"
                     /locus_tag="LY912_001401"
     CDS             31290..32519
                     /gene="hflX"
                     /locus_tag="LY912_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBM6955107.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEIAVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5521 c         6875 g         9367 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc tttttctttt
     1801 attattatga tgaatcaagc tttctgtttt tgtcacgtat gttgtaatct ttacgaaaga
     1861 gtagagttgg ctactcataa tcaaccatac ttcccatcat cgctaaatac gaaataaatc
     1921 agcattccta caccaatcaa agcacaagct gcaccaagaa aagggatgac attcccaaag
     1981 ttatctgtat tcataagtat gccaccaccc acaaacaaaa agccgccagc aatcaggttt
     2041 ttcattttat tcatctcctt tcttacgtta tagtatttcc ttctttcaat gagtattttg
     2101 aaagctatct tattgtatga tgttcttcta ggcctcttct ttattataca ggccattttc
     2161 gttatctcat agaaatattc ctttttatct gaaaactatt gtataccgta tgacattttt
     2221 cttcatgaag ttgtaagtat attctcattc aaatgaaaat ttcatcatag aagagattgt
     2281 atttctaaat tcttaagagt aaaatacgaa gtataacttg gatttggaag gatgattgga
     2341 tgaaagctat tacgcctgat atgacaacaa aatttaacaa acagtttcaa gcaaatatca
     2401 aacagcaggc attgcagcgg gcagttgtga agaacggaat tactgcttct gctgaaaatg
     2461 tttcagcaca tgtggagaat acaccggtat tttctataga tttggctacg gggaaagtgg
     2521 ctaatcaaat gcaatcgggg cgttgctgga tgtttgctgc actgaacaca ttccgtcata
     2581 agatgctgaa tcaattccat ttaaaagagt ttgaattatc acaaaattac acttttttct
     2641 gggataaata tgaaaaggca aattatttct atgaaaacat cattgcaaca ggaaaagagg
     2701 caatcgatag ccggaaagta gctttcttac tcgctactcc tcaacaagat ggcggccaat
     2761 gggatatgat cgtttcatta ttccaaaaat atggcgttgt gcctaaatcg gtgatgccgg
     2821 aaagtgcgaa tagttcaaat tctcgagatt tgaataacta cttgaacaaa ttactgcgta
     2881 aagatgcagt agtgttacgg aaaatggttg ctcaaggaga aacattagac gctattgaag
     2941 aaaagaaaga agaaatgcta gaaagcattt ataacttctt agctatctca ttaggaacac
     3001 ctccaaaaga attcgatttt gagtaccgcg atgaagaaaa gaactatcat cttgaccgag
     3061 gactgacacc acaaattttt tatgataaat acatcggtgt aaaattagat gattatgtta
     3121 gcgtgatcaa tgcaccaaca aaagacaaac cattcaatcg ttcttataca gtagagatgc
     3181 taggaaatgt cgttggcggg aaagaagtca aatatctgaa tgttgatatg gaaactttca
     3241 aaaaattagc gattgctcag cttgaagaag gagaatctgt ttggtttggt tgtgatgtag
     3301 gtcaatcttc tactagaact agtggcatca tggccttaga tgcttattca atggatgatc
     3361 tatttgatac ggattttaca atgactaaag ctgaacgttt agattttgga gaaagtctga
     3421 tgacccatgc gatggtattg accggtgttg acttagtaga cgggcaatca acaaaatgga
     3481 aagtcgaaaa tagctggggc gaaaaagttg gaaagaatgg cttctttgtt atgagtgatg
     3541 cctggatgga cgaatatacg taccaaatcg ttgtaagaaa agatttattg acgaaagagc
     3601 aattaaatgc gttcaatgaa gaaccaattg ttctatctcc gtgggatcca atgggtgctt
     3661 tagcatagac gagtatttca atgaagagta tgtagtaaag ataaaaagag ctggcttaag
     3721 ccagctcttt ttatctttaa agtccattcc ctgtttttta tggtccctgt gctataattc
     3781 taaataaagg ataaggattg gaaataatcc ttttatcatt aaaaatatga tgacgaagta
     3841 gaataaaatt gggagtaggg gggaaagtca tggatatcca aactgtttta tctgatctga
     3901 aattaaatgg taaagtgatt ccagttgttg gtggcgatgt taatcagacc tatcgtataa
     3961 aaaccgaaca tcgtgcttat tttttaaaaa tccatccgaa tgtaaaaaaa ggattttttg
     4021 aagcagaagt agacggatta aaagaactgt cagcattcgt acgtgtaccg gatacgtata
     4081 tgctaggtga aacaagtgaa ggcgcttatt tgttaatgga atggatcgag ccgggaaaag
     4141 gggatcaacg agatcttgct gcagctttag ctaatctcca tcagcaaaca gcgccacaat
     4201 ttggttttcg taaagataac tatttgggta cacttgttca gaaaaattct tttgaagaag
     4261 attggtggac ttttttcttt aaagatcggc ttgaatccca gatttctttg gcagaagaaa
     4321 cgaatcgatg gaatgtacag cgtcaagaaa agtatctgcg atttaaagaa cgtgtattga
     4381 aatcggttga accaaaaaag atcactccac gcctcttgca cggagacctg tggagtggta
     4441 atgtgttctt tgaccagcaa gggcatccag tttttgtcga cccagctgtt tcttatggga
     4501 atcgggaaca agatattgca atgagccagt tattcggtgg tttccgaccg gaatttttag
     4561 atgcttatca aactatattt ccattagaaa agggatggaa agaccgactg ccgatttacc
     4621 agttatatta tcttttggca catttgaata tgtttggaga aagttacggt tcccaagtag
     4681 atcaattact agaaaatttt taagaggagg gcgtgttttt ggcaaaaaaa tataccaaaa
     4741 agcatgaagt ttcatattat gagtgtgaca tcaaccaaac gatgacattt ccttcgatgt
     4801 taggagtagt tatcaaaacg tctgaagatc aaagcgacca gttgggaaga ggcagtgaat
     4861 tcgtcaatag ctttggactt acttgggtca tcacgaatta ttccatggag attaatcgtc
     4921 tccctagagt cggtgaagta atctcagtaa cgactcaagc catggagtac aataagtttt
     4981 tctgttatcg gaacttctgg atccatgatg aagatgggaa agaattagtc aaaatagaat
     5041 ctgttttcgt attgatggat tttgtgaatc gaaaaatgag cagtgttaat gaagagatca
     5101 ttgctccttt tgagagtgag aagatcaaga aaatcaagcg tcaggaaaaa attgaaaaga
     5161 ttgattcggg cttcatgttg ccatatcgtg ttcgttttta tgatatcgat agtaatcagc
     5221 atgttaataa tgcgatgtat tttaattgga tcattgacgt attaggatat gactttttga
     5281 ctacgcatgt tccagaaaaa gtaattattc gatttgataa agaagtagag tacgggaatg
     5341 agatcgaaag ccattttgaa caaatcccta tcgaaaatgg tgtcaaaaca aaacatgaaa
     5401 tccgaatgca agaacagctg tattgtgaag caaatattat atggaaaaat aaataaaaaa
     5461 gaggttgtga cagaaggggg caacttcaag aaataagaag aaatttacga aaattgtttc
     5521 tcaaattttt gtaaattttc gacttagttt tcgaagaagc tatttttgtc acagcctctc
     5581 tttttaagtt tagctattag ataatgatgt ttagttttgg ataaacgaaa tcaattcttc
     5641 acccgacaaa ccatagttta cagcaatcaa tagttttaaa cgtgcttttt gactattaat
     5701 actgttacag aaaataatcc ccattttttc tagttctttt cccccgcctt cataatcata
     5761 aacaggctct gcgattccat tgaaacaacg agaaacaagt actacaggga ttttttggac
     5821 aagaagcttt tccaaagcag ctaaggcttg tggagggaga ttccccgcac ctaaagcttc
     5881 gattaccaaa ccgtctactt tcgtatgggc gatggcttcc aataagtccc cttgcatccc
     5941 agcatatgct ttaacgatcg ggatagtccc atctacagcg gaaatgtcca gtcgctttgt
     6001 ttctaaaagt tcctgcaaga ataaaattcg attcttagtt actaagccga tgggacccaa
     6061 tgtaggtgtt cggaaagtag caacatttgt ggtatgggtc tttgtcacgt agcgtgcaga
     6121 atggatctca tcgttcatga ccaccaaaac ccccttatct agcgcttctt cacaacttgc
     6181 gacacgaatc gcactttcaa aattataaag gccgtcactt ccaagttcat tacttgaacg
     6241 cattgcccca gtcaaaacaa ttggtaattt gttgccaatc gttgtatcaa gaaaaaaagc
     6301 agtttcttct aatgtatctg taccgtgtgt gatcaccact ccggatatac ctgatgcata
     6361 agcggacaag atacgttctt ttaataccaa catgtgagaa ggcatgatgt gtggtgaggg
     6421 aagattgaag atatcttcaa ctaataattc tacatgcttg gggattgtga tttctgcatc
     6481 taataatggg tttgccacat caggactaac accgcccgtg agcatgtttt ctttcatggc
     6541 gatcgttccg ccggtgtgta gtacaagtat ttttttcatt ttacagactt ccttacgaat
     6601 aattttgcat agccgttaaa tcttattgta tactatataa aagagttttg ctatcagtga
     6661 agaataacga atagcctaac ttatcataaa aaagctgacc ttattaaaat ggaaaagact
     6721 caaccttgac ctcctaatac aatggagtat ctggttgagt ttcttttaca agaaagcagc
     6781 caaggaaatc aatcacgaag gtggccggaa atgatcagaa tcggattaac atcgtttaaa
     6841 gaacatgaca aattaactgg taaaaagaat aacactcttt atgaatatgc agggtttcta
     6901 cccttagtgg aattagatac tgcctattat ggaattcccc gaaagtcctc agttgagaat
     6961 tggataagtg aagtacctga atcatttcgc tttgtagtca aagtctatca aggaatcagc
     7021 ggtcaaggag actggaagcc ttattatcag accgaagaag agatgattgc gcatttttta
     7081 gatgttatgt cgccaatggt agatgctgga aagatgtttt gctttttagt ccaattcccc
     7141 tcatcattca aatgtacgaa agaaaatgtc cagtacttgc gcaaacttag aaagtggttt
     7201 gagggttatc ctgtttctat agaattgcgg gattattctt ggtacagcga tgaatttctt
     7261 gaacgtacaa gaaactttat gtctagagcc gctttttctt tagccatcat cgatgagcca
     7321 cagttgctga atacaacgat tccttttgat ccatttgtca ccaatccgaa ctttgctctt
     7381 tttcgattcc atggtaggaa tgcgcaagga tggcaagcaa atgataaaga gtggcgtaaa
     7441 aaaagaacgt tatatcgtta ttcagaaaaa gaactgcaag aactagcaca tgaagtcaaa
     7501 gtagttgatt ctaagacaaa agaggtaggt gtgattttta ataataattc tggtggtgat
     7561 gcggctgaaa atgcattagc actgcaaaaa atattaaata tcaagccaga tggactcaat
     7621 ccaacccaaa tggatctgtt ttaagggctt attttattca agaaaggggc gaagtctatg
     7681 atcaaagcta ttttttttga tattgacgga acattggtca ccaatcgttc aaaagcgttg
     7741 gaatcaacaa aacaagcaat tgaatatgct cggaaaaacg gcattttatg cggtgtagca
     7801 acggggcgca gcccagtaaa gatcaaagaa atcattgatg aattggaatt agatatgtat
     7861 gtcgtgtata atggtcaact ggtttttact gcagatcgca cgattatcga ccaccctttt
     7921 gaacaaaaag tattggaaca tattgttgaa tttgcagatg agaaccatcg acaaatcgtt
     7981 tttggtgcga gaaatcggtt agatggatca acgacgatgc tattaggaca atcgattttt
     8041 atcaagcgac tagtcagctt tttaccgcgt aaattcccgg tacgtctgat gaaaaaaatc
     8101 ctccaggttt ttagccctca ccgacaaaag gatcgttatg aaacgttaga gatattaaaa
     8161 gaaccaattt atcaatgtat attgctcagt ccggagtcag aacagaaaaa gttagaacat
     8221 cgctttcccg agtgtacgtt tcagcgttca aatacgtata ctgtagatat catcccaaaa
     8281 ggtggttcaa aattactagg catccaagct ttcgcaaatg ctgtcgaaat tgaaatggaa
     8341 gaaattatgg cattcggcga tcattacaat gatatcgaga tgctgaaagg tgtaggaatt
     8401 ggagtggcca tggggaatgc tcagatcgaa gtaaaacatg ctgcagactt tgtgactcaa
     8461 tcaaatgaag aagatgggat atacgaagga ctgaaacact tcggtctgat ttattagtca
     8521 atgaaagaag gaaaaaatca gtatggaagc agagacacct tttcaaaaag tagaaacatt
     8581 ccacaaaact tttgatccaa gaagaccaga gatacccacg gcttttacag aaaatgaagc
     8641 tcatacacgt gctgcgttca aaatagaaga acttgttgaa tttgttgcag ctacttcacc
     8701 taataaagaa caactgcatg aagctgttat gctgctgcac gaagcattag ataaagcaga
     8761 agaaaaaata cttggtaaaa cacagtgggg aagtgatccg ctggttgaac aagtagatgc
     8821 actgacagat atcctttact ttacttatgg ttctttttca ttactaggaa tagtgcctga
     8881 tcgaatattc gaaatcgtcc atcaggcaaa tatggggaaa ttatttccag atggaaaacc
     8941 tcattatgac cctgtaacaa ataaagtgtt gaaacctgaa aactggcaga tggaatatgc
     9001 tccagaacct aaaatcgcgg cagaaatcca acgtcagatt caagaagcga ttgctaagaa
     9061 gaaatccgct gatataggca tgtgcacaaa tgaaaaagag tgatcagagt ttcactattt
     9121 ttgttatctt tatacgatgg aaaaacaaaa gattttcgtt taagttagtg aatgcatgaa
     9181 aatagtatgc tataatctag aatagatgtc ttttgcacga gagacgtatt atttggattt
     9241 atgccaagca gaacgccatc tgttgcataa aagatgcata ctgaaaacgg aggaaccata
     9301 aatgggaaat aatgttatca tcggaatcgt cattgcaatc attatagtcg ccattgtcgt
     9361 ctttttggtt agttacttga tgaagaaaaa aaaccaagat cgattggatg ccttagaaaa
     9421 acgcaaggaa gaattatttg acttgccagt gattgaagaa gtcgatgatg ttaaaaaaat
     9481 gcatctggtt gggcaaagcc aaaatacctt tcgtgaatgg agtcaaaaat ggaatgacat
     9541 atctacttcc tcgttcgctg aactagaaag tcaaattttc gaagtggaaa acctcaatga
     9601 aagttttcgg ttcttaaaag gaaaaaaagc agttgttgaa gcagaagcta caatggacca
     9661 aatggagaaa caagtgacgg aaatccgtga aggtctaaag gaattgcggg aaacggaaga
     9721 acgcaactca ctagctgttc agcaggcact tgacgtctat gaagaactga aagaaaaagt
     9781 cagagaagac gagcatgaat acggaccagc tctttttgaa ttgcaaaaac agatcaaagt
     9841 gatcgaaaaa gaatttacgc agtttgtgac tttaaacact tctggagacc ctgttgaagc
     9901 ccgcgaggtt ttggataaag cagaaaaaca tacgtatgaa gtggaagctc tgatgaaaaa
     9961 aattccaccg ctgtatgagg agctccatac cactttccct gaacaacttg aagaaatcag
    10021 tgatacttac gagaaattga tggaagaaca atatgtattc ccagaagaag atcttgctga
    10081 agatatcgca aaagtaagtc gaagaattga aaattcatta gccaatcttg aaaaaacaga
    10141 agttgaaacg gtcgaatttg aaaaccgtga aacagctgat ttgattgatt cgttatatga
    10201 tatcttagaa cgggaaatgg aagctcagag atatgtaaaa actaaccaat caacgattgc
    10261 agagtatatc aaacatacaa caaagaataa ccgtcaatta ttgattgagc tggatcacac
    10321 atctcaaagc tatacattga accacaatga aattggccgt gtacgaggtt tccaaaccga
    10381 agtggaagaa atggaacgtc aaaatgaaca gatgattcca cagatccgtc aacacgaaat
    10441 tccttattca gaagtgcgca cgttctataa aacagtcttc aaagtcttag aagatatcga
    10501 aaagcaacaa gtagagatcg acgactcatt acatgaattg agaaaaggcg aaaaagaagc
    10561 gcaagaaaag atcgatacat tcgaattcaa attgcgcagt ttgaaacgtt ttgtagaaaa
    10621 acaacgtttg cctggcttgc cgaatgatta cctagaattc ttttttgttg ctactgaccg
    10681 tattgaagaa ctaagtgttg tcttgaataa aattcgagta aacatggaag aggtcaatcg
    10741 tttagttgct ctatgtgaag aagatctaga attattagat aagaagacac atgatttagt
    10801 agatgcagca gcattaacgg agcaaatgct ccaatatgca aatcgttatc gtcatacaca
    10861 cgaagaagtg agagaagcaa ttgataaaag ctactattta ttcaataaag aatatcacta
    10921 tcaagaagca ttagacgaaa tcggtacagc attagagcga gtagaacctg gtgctttcaa
    10981 acgcatcgaa gatttttatt ttaatcatcc agacttagta taaagcaaaa aagttagtaa
    11041 accagcaaga gcaagacgga ttattgtctt gttcttgtct ttttttgtat atttgaaaat
    11101 tgaaacaagt gaaaatttca cctgctcttg aaagcacctt ggacaaccgt tataatagaa
    11161 aagaatttca aaaaagaggg gtttcttatg atatattttg ataacagtgc aacaacccca
    11221 atctttccgc aaagcttaga tgcatatgta aaaaccagtc agcggattat tgggaatcca
    11281 tcaagcttgc atgatttagg caatcaagct aaccggttgt tgcagcaagc aagaaagcag
    11341 atcgctgatt tgatccatgt agaaccagaa gaaatctatt ttacttcagg cggaacagaa
    11401 ggagataact gggtattaaa aggaacgatg atcgaaaaaa gagaatatgg gaatcatatg
    11461 atcatttcag gagtcgaaca tccggccgtc agcgagacag cagaacaatt aaaagaatta
    11521 ggaatcgaag taagtatcgc cccagtggat aaacgcggat ttgtacgtgt cgacgaattg
    11581 aaagaattaa taagaaaaga gacagtatta gtctctgtta tggctgtgaa taatgaagta
    11641 ggatcgattc agcccatcca ggaaatcagt gatcttttgg atgattttcc taaaattcat
    11701 ttccatgtag atgctgttca ggcgattgga aaagtaccat tctcgcaatg gttgacagaa
    11761 agagttgatt ttgcaacatt ttcagctcat aaattccatg gcccacgggg aactggtttc
    11821 atttattgga aaaagggtcg tcgtttagca ccattactga caggtggagg gcaagaaaga
    11881 aatcagcgaa gtgggacaga aaatgttcca ggtattgtgg ctatggttaa agctttacgt
    11941 ttatcattag agataaagga acaaaaacct gagcagacac aacgcttaaa agtagctcta
    12001 atcaatgcgt tgaagacgta tgagaaagtg acgatttttt cagaaggaac tgactatgca
    12061 ccgcatattt tatgttttgc tctaaaagga attcgcggcg aagttctcgt ccatgcctta
    12121 gaagaaaaac aaatatttgt ttctactact agtgcctgct cctcacgtaa acatatggca
    12181 agcagtacat tgcacgcaat gcatgtacca aatgatctgg ctacatctgc tgttcgaatc
    12241 agcttagatg aaaacaattc gcttgcagaa gtcgagcaat ttatgattat tttcaagcag
    12301 ctttataaga aattttctgc aatcaattaa aagaggagtg ttcttgtgaa atacagtgaa
    12361 attatggtcc gttatgggga actttcgaca aaaggaaaga atcgaaaaag ctttatcatg
    12421 caactagcac aaaatgtcag acaagctttg aaagactttc cagaaatcaa aatccatgct
    12481 gatcgggacc ggatgcatct tttattgaat ggcgcagacg ggcagctagt tattccaaaa
    12541 ctagcaaaaa tatttgggat ccaaaatttc tctccaagta ttcgtgtaga aaaagatgtc
    12601 gaagttttga aacaagctgt tcaagacatc atgaaagaaa tttatactgg gaaagaaaca
    12661 tttaaaatta tcgctaaaag aagcgatcac caatttgaat tgacaagtaa tgaattgaat
    12721 caaacattag gtaatgctgt ttttgatatt ttcccgcata tccaagttca aatgcgtcaa
    12781 ccagatattc cattacgtgt agagattcgg cgtgatggcg cttatctatc gtatgaaacg
    12841 atcaagggag ctggaggatt gcccgtagga acaagcggaa aaggaatgct tatgctttct
    12901 ggggggattg attctcctgt agcagggtac tttgccatga agcggggagt ggaaattgaa
    12961 gctgttcatt ttgctagtcc gccgtataca agtgaacaag cactgcaaaa agcaaaagat
    13021 ctaacagcca aactagcacc ttatgtggga acgatccatt ttatcgaagt gccatttacc
    13081 gagattcaag aagaaatcaa aaagtcagtg ccacaaggat attggatgac aattactcgt
    13141 cgaatgatgt tgcgtttgac cgatgaaatt cgccgtattc gtcatggttt agtcattttg
    13201 aatggtgaat cattaggtca agtggcttca caaactttgc aaagtatggt ggctatcaat
    13261 gaagtaacga atacgccaat cattcggcct gtagcgacaa tggataaact tgaaatcatt
    13321 gaagtagcag aacagatcga tacatttaat ctttctatcc agccttttga agattgctgt
    13381 acgatttttg ctcctccaca gccaaaaaca cgccctcaac tggaaaaggt ccatcaatat
    13441 gaagagcgtt tagcaataga tgaaatgatc caacgagcac tagctggctt gaagatggaa
    13501 gagatacaag cagaatcgtc taatgaaaaa actgaagaat tttcagaatt gctataagag
    13561 gttatgaaaa tagtgttttg accagagtat tagagaaaca aaacgaaaaa atagctccat
    13621 gtattttacc gtttttgaac taatgtcgaa gattagctga ttgaatacca tttatcaaga
    13681 agttatggaa aagccggttc ttttttacta actgaaaaat aaaattttat ttagagatca
    13741 agctacagtt gataaatgat ataaaaaaga gaatttccca tgaaatagcg aggttgtgac
    13801 agaagtgggc agcttcaaga aataagaagg aatttacgaa aattgctttt caaatttttg
    13861 tgaaatttcg gcttattttt cgaagaagtt acttctggaa caccgtgtat cagaggttgc
    13921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
    13981 tacgtttggt tgagcttatt accgcagatg caagcttttg aacaccgttt tatttgtctc
    14041 acaccctttt ccttcctact tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat
    14101 atgtgaaatt attaacaagg agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag
    14161 caactgcgaa aagattacct ttatatttac gctacttgaa gatgctggat gactcaggta
    14221 taagtagaat caaatcaaat gagttcagcg aaatcaccca aattccttct gcaacgatcc
    14281 gcagagactt ctcgcaatta ggcgagctag gcagaagcgg atatggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtag taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg tatttttttg tatgaaaaag
    21301 taaataaatt taagaggcta tgaaagagcc accttgtatc aaggaataag aacaaacaaa
    21361 aatggcttct catgtttttc atttgttttc tcttatattc aggacaaggt gctgatttca
    21421 taacctctta tttattcttc atctggtgtc attaccattg gcaaaatcat tggatgtctt
    21481 tctgtacgtt cgaataagaa aggctgaagc gcgccagtca tcgcttcttt caatttatat
    21541 tctgaacagt caggtccatt caaacattct cttaaagcgt ggaataagat tcgctgagct
    21601 tcattgatca tttctcctga ttctcgcatg tagacaaatc cacgagagag aatatctgga
    21661 ccagccaaga tttctttttt cttgatatcc actgtcgcga cagctaatac aagaccttct
    21721 tctgaaagca ggtgacggtc acgtaaaacg acattaccaa tatcaccgat cccgctacca
    21781 tcgatataca catctccagc cacaaaatgc ccagcaggac gcgcagaatc gctagttaac
    21841 gctaaaacat cgccattttc catgatgaag cagttttctg caggaacacc tacatcttgt
    21901 gctagagaag catgtacttt caacatgcgg aattctccgt ggacaggaat aaaatatttt
    21961 ggcttcatca aacgaagcat taatttttgt tcttcttgtc caccgtgacc ggaagtatgg
    22021 atgttattga tttttccgtg aatcacttct gcaccagctt cagacagcaa attgatcaaa
    22081 tgattgacac ttgttgtatt accaggaata ggtgaacttg aaaagatcac tgtatcgtct
    22141 ggctggattt ggatttgacg gtgagtacca ttcgcgatgc ggctcaacgc ggccatcgct
    22201 tctccttgag aacctgtaca taggatcatc gtttcattgg caggcaagcg attgatttcg
    22261 tgtgcatcta caaatgtgcc gtctggaact ttgatatatc ctaaacgttg accgttgacg
    22321 atggcatttt ccatgcttcg tccgaaaaca gcgattttac gaccagttgc cacagcggca
    22381 tctgctgctt gctgcaaacg gaagatgtta gaagcaaagc tggcaaaaat gatacgtcct
    22441 tcgatttttg aaaagatctt caaaatagaa tgcccaatcg ttttttctga tttagtaaat
    22501 gttggaatct cagcatttgt actatcagat aaaaggcaca agactccttc ttccccgata
    22561 cgagccattt tatgcaagtt tgctggttcg ccaacaggag tgaaatcgaa tttgaagtct
    22621 ccagtcgcta cgatatttcc agaaggtgtt ttcaccacga tccctaatgc atctgggata
    22681 ctatgggtcg ttctgaaaaa gctgacagaa gtctttctaa aacggatgat cgtatcttca
    22741 ttgatctcat ggagctctgc atctcgaagc aagccatgct catctaattt gtttgtgatc
    22801 aacgctaatg cgagaggacc agcatagata ggaatatttg cttgtttcag caagtagggt
    22861 attccgccga tgtggtcttc gtgcccgtga gtaatcacca aggcttttac tttgtgtaag
    22921 ttttgtatga tgtagctgta gtcgggaatg acatagtcaa ttccaagtaa atcgtcttcc
    22981 gggaatttga tcccggcatc aatcaaaatg atttcatctt ggaattgtac cccatacgta
    23041 tttttcccga tttcacctaa tccaccaata gcaaagacgc ctgtctcgtt atttttgatg
    23101 gaaagtttca tattaaaact ccactaatga gaaatcagca ttttcttttt cgtactctag
    23161 atgacttcct tctagaagtt gaacgaattc aatattgtat ggggtatttt cttccacacg
    23221 ttggcgagcg tctacatcgc tttttgcctc aatgtaaaga gattttgttt cttcccgttt
    23281 agggttgcgt acttttgttt cttgataata aactttatag atcattgttt tgtctccttt
    23341 atctgcgtaa agcagtgatt tagctagttg atttttttag acaacacaaa acgaggggac
    23401 aagccacctg gtttttcata tgctttgact agaatactgg attcgagtca aagagacaag
    23461 cctcgttttt gcttatctgt tcggatattt tttcaaccgt accttctgta taaaaaatat
    23521 acaacaatta attgttattc tagcataaaa cagcaaataa gtatagaaat caactagatt
    23581 gaaagaaaaa atcaatgttt atcatcccgc tataatcata atgacttttt tatgagagaa
    23641 gtgttctatt aataggctcg ttgtgctatc atttttagta atgaaaatgt aacaaaagat
    23701 taaaaggaga tgagaaagtg aaactaatgt ggcattatac catgcgttat aagaaattct
    23761 tgtttttcaa tttcatatgc gtatttggtt ttattttgat tgaattagga cttcctacga
    23821 ttttagcacg tatgatcgat gtaggaatcc gcaatgatga ttttgattat gtgaagcaac
    23881 aagggatatt tatgatcgtt attactgtaa tcggtattat tttgaatatc ttgttaggtt
    23941 attttggttc gaggattacg actaatatcg tagcagatat tcgagatgat ttgttcgaaa
    24001 agatccaaag ttattcgcat caggaatacg aaaatctagg cgtatcttca ttgatcactc
    24061 gtacaacaaa cgatgcttat cagatcatgt tgttcctgca aaatatttta cgtatcggtt
    24121 ttatggcacc aatgatgttc attgtcagtt tgtacatggt catgcgtaca agtgtgacac
    24181 tcagtttgta tgtagtaggt gcattacctt tactattatt ggcagtcgta gcgattgcta
    24241 aggtgtctga accgttatct aaaaagcaac aaaaaaactt agataaaatc aacagtatct
    24301 tgcgggaaaa tctttcagga ttgcgtgtga ttcgtgcatt cgtcaatgaa aagtttgaag
    24361 aaaaacgttt tgctgtagtc aatgagaatt atgcttctag ttcaaaaagc ttattccgtt
    24421 tgatggctgt tgcacaaccg ggtttttatt tcttatttaa tatcgtaatg gtattgatca
    24481 tctggagcgg ggcagtgcaa atcgatgcag gcgagcttcg tgtaggagat ttgattgcgt
    24541 ttatcgagta tatattccat gccttgttct cattcatgtt atttgctagt gtgttcatga
    24601 tgtatccaag agcagctgtt tcagctggac gtatccaaga agccctagat gccaaacctt
    24661 cgattgtaga agatccaaat ggtatatctg atacaaaaac taaagggtat atcgaatttc
    24721 aaaatgtaac atttgcttat ccaggccatt cgcaagagcc agtgatacga aatgtcagtt
    24781 ttacagcctc tccaggagag accgttgctt ttattggaag taccggtagc ggaaaatcta
    24841 cgttgatcca attgatccct cgcttttatg atgtgagtga aggaaagatc ttgatcgatg
    24901 gagtagacgt gagagattat cggctaagca agttgcgaga taagattggg tttattccgc
    24961 aaaaagcgct gctatttact ggaacgattg cagataattt gcgatacggg aaagaagatg
    25021 ctacgcaaga agaaatggaa cgtgcagctg agattgctca agcttcagaa ttcatttctc
    25081 gaaaaccaga tggatttaat gaacatttat cagaaggtgg ttccaatttt tcaggtggac
    25141 aaaaacaacg attggcaata gccagagcca tcatacgccg tccggaaatc tatatttttg
    25201 atgacagctt ttctgcatta gattatcaaa cggatgcgaa gttacgtgct cgtctgaaaa
    25261 aagaaacgac agaatctact gtattgatcg tagcacaacg tgtgggaacg atcatgcatg
    25321 cagataagat catcgtatta aatgaaggag aagtcgtcgg tatggggacg catcgggagt
    25381 tgttggaaaa atgcccgatt tattatgata ttgccgcttc tcaattatca aaggaggaat
    25441 tagcatgaaa aaaacctttt cttccttaaa acgtttagct cgatatatca gaccgtatcg
    25501 tgagactttt cttttagtga tcctatttac agttctgaca gtggctttca acgtggcttt
    25561 gccatatgtt acaggacttc ctactacaga aatcagccgt aatattgcca atggcgaatc
    25621 aatcaatttt tcttatatat tcaaatgtct catttggatc acagttgttg gaatagggta
    25681 ttgtatttcg caattacttt ctggtgtttt gatgacaaat gtcgttcaaa gtgccatgca
    25741 tgatttgaga agagacatag aagaaaaaat caatcgtctt ccggtttcat atttcgataa
    25801 aaaccagcaa ggaaatattt tgtctcgtgt gacgaatgat gtagatgcag tcagcggtgc
    25861 tttacaacaa gcttttattg gtatcgtaaa tgcgatattg ggaattacgt tggctgcagc
    25921 aatgatgttt tatatccagc cgatgatggc gctgatctct atgatcatga ttccaacatc
    25981 gatctggatc tcaaaacgag tgatcaatgc ttcgcagaaa tattttcaaa gcatgcagaa
    26041 ttctcttggt gagctaaacg gctacgtcca agaaaatatg acaggtttta gtgtattgaa
    26101 agtatatgga cgcgaaaaag aaacattgga aggattcaaa aaagttaatc acagcttgaa
    26161 atactttggg tttcgtgcag cattcatttc tggcttgatg atgcctctag ttcaattaac
    26221 tgcctatgct acttatattg gtatggctgt tctaggaagc ttttatgtta ttactggggc
    26281 gatcgttgtc ggtcaactac aagcattcat ccaatatatt tggcaaatca gtcagccaat
    26341 ggggaacgtg acacaattgt cttcagtttt gcaaagtgca tcagcggcaa cgaaacgtgt
    26401 attcgagatt ttagatgagc cagaagaaaa agaaaacaaa gtagatgctt cactgccaga
    26461 aacgatttta ggagatgtga cattcgatca tgtcgatttt gcatatgatc cgaagaaacc
    26521 attaatccaa gatttgaatt ttgaagtgaa agctggtcaa accgtagctg tggtcggtcc
    26581 gaccggtgcc ggcaagacga cattgatcaa tctattgatg cgtttttatg acgtagacaa
    26641 aggagcaata aggattgatg gaatcgacac caaatcaatg agtcgcagtg atgtgcgttc
    26701 gctatttggt atggtcttgc aagatgcatg gctttatcaa ggaacgattg cagataatat
    26761 ccgcttcgga aagcttgatg cgacagatta tgaagtagtt gatgctgcga aaacagcaaa
    26821 cgtagatcat tttatccgaa cgatgccaga tggatatgat atggccatca attctgaggg
    26881 agacaatgtg tctttaggac aaaaacagtt gctgacgatt gcccgagcag tggtctccga
    26941 tcctaaaatc ttgattttag atgaagcaac aagttcagta gacacccgtt tagaagcgtt
    27001 gattcaaaaa gcaatggatc gcgtgatgga gggacggaca agtttcgtca tcgctcaccg
    27061 tttatcgaca atccgtgatg cagatctgat tctagtgatg gatcaaggtc agatcattga
    27121 aaaaggaacg catgagagtt tattggcaca aggtggattt tatgaaaaac tgtataacag
    27181 ccaatttgct gaggaagcag aataagtcat ataagaataa aacagtttaa aacttatttt
    27241 ttgttctcta ttcttgataa tggtaaagta aagttatcaa gaaaagtgag gacacggaga
    27301 tggaacagtt tttaaatgaa aaaattactg aagccaaaag agaagttgat cgtttaacgc
    27361 acgtctgtca gacgaagcct tttgattcag ctgatttttt tgaaaatgag tttcaaatcg
    27421 aacgcttggc agcacaaata gaagtgtacg aattaatttt aaaaaaagta atagaagaaa
    27481 atatagatgt acaataaaaa caggtaaaac gtcagttacc agatactgta aatagacatc
    27541 tggcctgagc aggttttacc tgtttttttt cttatgaaat aaatatatgc tatgatacct
    27601 ttattcaata ggattagttt ctacaaaaaa tgaaaggaga aaaataaata tggaacggtt
    27661 tatagcatca aatgccacag tgattggtga tgtgacattg tcagaagatg tgacgatctg
    27721 gtatcaagct gttttacgcg gggacagtaa ttggataaaa ataggacaaa gaacgaatat
    27781 ccaagatggt acaatcatcc atgtcgatca tgatgcacct gtagatattg cggagaatgt
    27841 gacggtagga catcagtgca tgctacatgg ctgtacaatc gaaaaagggg cgctgatcgg
    27901 gatggggacc acgatattga atcatgcggt tattggtgag aatagtttga ttggtgctgg
    27961 atcattagta acagaaggaa aagttattcc tcctaatgtc ttggcttttg gtcgcccagc
    28021 taaagtgatc cgtcctttga caaaagaaga aatacaaaaa aacaaagaaa acatccagca
    28081 ttatgtcgag ataggtcgga tgcatgcgca aggaaaattc aaggagcaaa gataggcagt
    28141 agcatccata aaataaaaaa ggatggtcag tttgagttga ccatcctttt ttatttggtt
    28201 tagataagag agcttaaaaa agcttccttt gaaacagatt aatttaatga agaactgttt
    28261 tccatgactt catcgatcaa tccatatgct tttgcttgtt cagctgtcat atagttgtca
    28321 cgatctgtat ctttttcaat cacttcaagc ggttgtccag tgcgttcagc taaaattttg
    28381 tttaagcgtt cgcgtgtttg caaaatatgg cgtgccgcaa tttcgatttc agttgcttgc
    28441 ccttgagcgc cgccaagagg ttgatggatc atgatctcag catttggtaa agcaaatcgt
    28501 ttaccttttg taccagctgt cagcaagaag cttcccattg aagcagccat acccataaca
    28561 attgtttgga catctgcttt gacaaagttc attgtgtcgt aaatagccat acctgctgta
    28621 actgaaccac caggagaatt gatataaaga tagatatctt tttcagaatc ttgagcgtct
    28681 aagaaaagca attgggcgat gatcgaatta gcaagatcat ctgttacttg gccgcttaac
    28741 atgatgatac ggtctttcaa taaacgtgag tagatatcgt aagctctttc acctcgtgaa
    28801 gattgttcaa tgactgtagg aattaaattc ataatagagt tcctccttga tttcgtttag
    28861 aaatagtgta ccataattta gtttctaata cctaaaatgt agtatacatt tttggtcaaa
    28921 aaaggtcaaa taaaaaactt aggcaaatta gtcgcataaa cccgctttat ggtatgataa
    28981 gcagagaaac aaaacaagga ggaacaacag attgatagtt ggtattactg gccttatcgg
    29041 agtgctgaca ggtgctgtag ttgtctatat cggcatgata ctgcaaatgc gtcacttgga
    29101 aaataaagaa cagcgtagac gtgaattgga attgaaagtc aaagaaatcg agacgctgaa
    29161 tcaattaaat aaaaagatca acgagatctt gcaaaaacgg acaacgctga tggaagaata
    29221 tgtcagcttt gatgcatttg atgattgtta tatcacgatt gacgattttg cgtatctcca
    29281 atcattttca gcgcaaaata gtttttatct gccaaattat attttagacg agctatttaa
    29341 gaatatctcc catcgaaaag tgattttatc tccagatgaa acaatgaaga ttggtggata
    29401 tgcttataaa ggcggacgcg tgattttaga gaattttacg gatagtctga ctgaaatgat
    29461 caatgaaaaa aaagctcagt tgaagactat gacgcgccag ccgattggtt tcttctcgaa
    29521 agatgatgtt tgaagctgat attttgaagc attgccgttg cacatgagag cgtggtaatg
    29581 ctttcttttt ttcttaatga tacaatagaa ctgaacggag tgaagaaaga tgttacaaat
    29641 ctatgcccat cgcggaagca gcggcaccca cccagaaaat acgcttcctg catttgcaga
    29701 agctgtacga gtaggtgcag atggtatcga actagatgtc catctaagca aagatggtta
    29761 tttgatcgtt atgcacgacg aagaagtgga ccggacgact aacggtaaag ggctgattcg
    29821 agaaaaaaca ttggaagaac tcaaaaaatt gaatgcaggg ggcaaattca gcaaagaatt
    29881 tccagcagct aaagttcctg aattgagaga agtgttagga ctgctcctcc aaaaaaatta
    29941 ccgagggatg ctaatgattg aaattaaaac tgatcagtat gaatatcccg gtatcgaaga
    30001 aaaattagcc gaaacattaa aaagtagaga ttggcctttt caacatgcat attgcagctt
    30061 tcatttggat tctttggaaa aaatcgcatt actggaaccg gagatacagc tggacttatt
    30121 gatgagtact tctgataaaa agatccaact agcagcagaa accccttata tagaaggagt
    30181 acatccaaaa aatacttggt tgttcgaaca tccagtccag gcagctgatt ttccaaaagc
    30241 aattcgtgca tggacgatta acgatgaaga agaaatggcc aaatgtcaag aactcaaaat
    30301 agatggaata ataactgatt ttccggagaa agctcttcgg tggaaacaat caacgaaaag
    30361 taggtaaaat atggaaaaag tattagtgat cgtcggtccg acagcagtcg gtaaaacagc
    30421 gctaagtgtg gaactcgcac aactatttgg aggagagatc atcagtggtg attcattgca
    30481 aatctataaa aatctggata tcggtacagc aaaaatcaaa gaagaagaga tgaataatgt
    30541 tccgcatcat ttgattgatg tgatcgaacc tactcaacgt tactcagccg ctgattttca
    30601 gcattcaggt cgacaattga ttaccgagat tgcgaaccga gggcacctac ctatcatagc
    30661 tggtggtacg ggtctctata tccaatccct tctatatgat tatcagttag gagcgacaga
    30721 agaagcgaat cctgagatta gaaaaaagta tgaaacgtta gctgaaacaa ttggttccca
    30781 agcattatgg aatcagttga aagaaaaaga cccggcagct gctgagaaaa tccactggaa
    30841 caatcaacgc aaagtgataa gagctctgga agttttagag acgacaggac atagtatcac
    30901 ggcacctaaa gaagagccaa agcaattgta tgattacctc atgattggat tagatacgaa
    30961 gcgtagtatt ctttatgaac gaatcaatca aagagtcgat ttgatgctag cagaaggttt
    31021 agtagcagaa gcgcgtaagg tgtatgagct tggagaagtc caggccagtc aaggtattgg
    31081 atataaagaa tttttccctt attttgaagg gaaagaaaca ttggaagaag caacagaaca
    31141 agtcaaacta cattcgagaa gatacgcgaa acgtcagttg acgtggtttc gtaaccgttt
    31201 ggatgcacag tggtttgatc ttataagtga gccaaatcaa aaaagtcaga ttgagcaaac
    31261 aatcaaaaaa tggctggagg cggaataaaa tggaagaaaa agtgatcatc gtaggggtag
    31321 aaaccgaagc aaaccagcgt tacttttcag agtcaatgga agagctagtt cagctgacga
    31381 ataccgcatc aggagaagtc gtattcacaa ttacacaaaa gagaccacaa gtggatcggc
    31441 aaacgattat cggtaaaggg aaattacaag aattagttca acaagcggat gcgcatgaag
    31501 cggatttgat catctttaat catgagctaa ctccgagaca gagccaactg attaccgatg
    31561 ctgttggtct tccggtaatt gatcgcgtgc agcttatctt agatattttt gcgatgcgtg
    31621 ctcgttcgaa agaagggaag ctgcaggttg aacttgctca gttagaatac ctgttgcctc
    31681 gtttagtagg gcaagggaaa acattatctc gtcttggcgg tgggatcgga acaagagggc
    31741 caggtgaaac aaagttagaa acagaccgcc gacatatacg gaataaaatt tttgctgtta
    31801 agaaagaatt gaaagaagta gaagctcatc gagagcgcaa tcgccaaaaa agaaaaaata
    31861 gcgagatttt tcagattgga cttattggct acacgaatgc cgggaagtca actatcttga
    31921 atctattgac acaagcggat acttattcga aagatcaatt gtttgcaacg ttagatccat
    31981 tgactaagag atggcgtttt gctgaaggat ttgagattgc tgtaacggat accgtcgggt
    32041 tcatccaaga cctgcctacg caactgatcg atgctttcca ttctacatta gaagaaagtc
    32101 aaaatatgga tcttttgcta catgtagtcg atgctagttc tccagatcgt attttacagg
    32161 agcagactgt cttaaaattg atggatgaac tgaatatgaa agaaatgccg atactgactg
    32221 tttacaataa ggcagaccag atcgacccag cgatgttcac gcctacgcta ttcccaaatg
    32281 tattgatttc tactcagacg aaagaaggta agatggcgtt gatcgaagca atcaaacgtc
    32341 agctgatgga actaatgacc ccttatacac tttctgtgcc aagcaacgaa ggacagaaat
    32401 taagcgagtt gagaagacaa acaatggttt tggacgaagc gtacatggaa gaaacaaacg
    32461 aatatgaagt taaagggttt gcaaaaacca attcaaaatg gttaagaaaa aaccaataaa
    32521 attttatttt tttaa
//
LOCUS       DAFKHN010000032        29947 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFKHN010000032 DAFKHN010000000
VERSION     DAFKHN010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.032"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(26..328)
                     /locus_tag="LY912_001402"
     CDS             complement(26..328)
                     /locus_tag="LY912_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6955108.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="LY912_001403"
     CDS             complement(353..2446)
                     /locus_tag="LY912_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBM6955109.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="LY912_001404"
     CDS             complement(2935..3699)
                     /locus_tag="LY912_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBM6955110.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="LY912_001405"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="LY912_001405"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBM6955111.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="LY912_001406"
     CDS             complement(4704..5780)
                     /locus_tag="LY912_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBM6955112.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="LY912_001407"
     CDS             complement(5804..6397)
                     /locus_tag="LY912_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBM6955113.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="LY912_001408"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="LY912_001408"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBM6955114.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="LY912_001409"
     CDS             complement(8067..8366)
                     /locus_tag="LY912_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBM6955115.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="LY912_001410"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="LY912_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBM6955116.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="LY912_001411"
     CDS             complement(10121..11032)
                     /locus_tag="LY912_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBM6955117.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="LY912_001412"
     CDS             11152..12009
                     /locus_tag="LY912_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBM6955118.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="LY912_001413"
     CDS             complement(12196..12558)
                     /locus_tag="LY912_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBM6955119.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            12904..14343
                     /locus_tag="LY912_001414"
     CDS             12904..14343
                     /locus_tag="LY912_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955120.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="LY912_001415"
     CDS             complement(14350..16902)
                     /locus_tag="LY912_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBM6955121.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="LY912_001416"
     CDS             complement(17016..18347)
                     /locus_tag="LY912_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6955122.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="LY912_001417"
     CDS             complement(18313..19791)
                     /locus_tag="LY912_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6955123.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="LY912_001418"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="LY912_001418"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBM6955124.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="LY912_001419"
     CDS             22401..23828
                     /locus_tag="LY912_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955125.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="LY912_001420"
     CDS             complement(23920..24285)
                     /locus_tag="LY912_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBM6955126.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="LY912_001421"
     CDS             complement(24282..24647)
                     /locus_tag="LY912_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBM6955127.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="LY912_001422"
     CDS             complement(24839..25087)
                     /locus_tag="LY912_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955128.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="LY912_001423"
     CDS             25086..25214
                     /locus_tag="LY912_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBM6955129.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="LY912_001424"
     CDS             25271..26965
                     /locus_tag="LY912_001424"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBM6955130.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            26969..27088
                     /locus_tag="LY912_001425"
                     /pseudo
     CDS             26969..27088
                     /locus_tag="LY912_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            27616..28749
                     /locus_tag="LY912_001426"
     CDS             27616..28749
                     /locus_tag="LY912_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBM6955131.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28780..29100
                     /locus_tag="LY912_001427"
     CDS             28780..29100
                     /locus_tag="LY912_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBM6955132.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29129..29593)
                     /locus_tag="LY912_001428"
     CDS             complement(29129..29593)
                     /locus_tag="LY912_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955133.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29724..>29947)
                     /locus_tag="LY912_001429"
     CDS             complement(29724..>29947)
                     /locus_tag="LY912_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6955134.1"
                     /translation="VSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAA
                     VNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT         9031 a         6212 c         5170 g         9534 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca
    27121 agtaataaga gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt
    27181 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt
    27241 tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt
    27301 aataccgaga aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt
    27361 gaaaacaact attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac
    27421 aactatttca atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa
    27481 tacataagac tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa
    27541 gatctccttt aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg
    27601 aaaggagcat ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga
    27661 aacgtagatg atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca
    27721 gccatttgcg gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg
    27781 tatgttgtag gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca
    27841 ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc
    27901 tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg
    27961 cttttcggat ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga
    28021 gttccttatg cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa
    28081 gttttatttc tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta
    28141 aaaaaaggcg atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa
    28201 ttcgctgtta tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta
    28261 gataaagcgg ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct
    28321 ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga
    28381 atggacggat tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc
    28441 acaatctctc cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta
    28501 actggtgttt atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat
    28561 atcgctgtca agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg
    28621 attgcagaag gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa
    28681 gcagcacaag catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg
    28741 aaaccttgaa ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat
    28801 acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc
    28861 ttctatttcc aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt
    28921 ttctatattt ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat
    28981 ttttatttgg ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac
    29041 atttttattt acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga
    29101 gaatttttca aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag
    29161 cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa
    29221 acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc
    29281 tgatttccgc taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca
    29341 gggcacaaag atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg
    29401 ctcctccgac gatggtttct ttttcatcta agaccacata ccattgagga atactttcct
    29461 tattagcgat tccagtacga atactttcct catacacaac agcaggaact ccccattttg
    29521 atgaaaacca attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt
    29581 tatatgtaac caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag
    29641 tctttatgaa aattagcaat gacaacaata gtgatgtaaa aaaaaaacgg aaaacaatca
    29701 cttgttctcc gttttttgat taatcaagca tctaaagctt cttttcttct ttcttggatc
    29761 gtagctacct tgacgaacgg tagatagatc aaaatagaaa gaaccaaatt gacagcggct
    29821 agtacaccac ctgcaatact ttttgttgcc aatacaccgc caataattgg tggagttacc
    29881 catggaggca taacggtagc tgctggcact aaacctgtag aagtcgcaaa gtaagcaaca
    29941 ctaacta
//
LOCUS       DAFKHN010000033        27595 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFKHN010000033 DAFKHN010000000
VERSION     DAFKHN010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.033"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(117..1061)
                     /locus_tag="LY912_001430"
     CDS             complement(117..1061)
                     /locus_tag="LY912_001430"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBM6955135.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1357..2301)
                     /locus_tag="LY912_001431"
     CDS             complement(1357..2301)
                     /locus_tag="LY912_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955136.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2522..3736
                     /locus_tag="LY912_001432"
     CDS             2522..3736
                     /locus_tag="LY912_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6955137.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3758..5773
                     /locus_tag="LY912_001433"
     CDS             3758..5773
                     /locus_tag="LY912_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBM6955138.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5856..7229)
                     /locus_tag="LY912_001434"
     CDS             complement(5856..7229)
                     /locus_tag="LY912_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBM6955139.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7255..7539)
                     /locus_tag="LY912_001435"
     CDS             complement(7255..7539)
                     /locus_tag="LY912_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6955140.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7541..9556)
                     /locus_tag="LY912_001436"
     CDS             complement(7541..9556)
                     /locus_tag="LY912_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBM6955141.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9735..10040)
                     /locus_tag="LY912_001437"
     CDS             complement(9735..10040)
                     /locus_tag="LY912_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBM6955142.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10129..11160)
                     /locus_tag="LY912_001438"
     CDS             complement(10129..11160)
                     /locus_tag="LY912_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBM6955143.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11367..12242
                     /locus_tag="LY912_001439"
     CDS             11367..12242
                     /locus_tag="LY912_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBM6955144.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12394..13236)
                     /locus_tag="LY912_001440"
     CDS             complement(12394..13236)
                     /locus_tag="LY912_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBM6955145.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13328..15205)
                     /locus_tag="LY912_001441"
     CDS             complement(13328..15205)
                     /locus_tag="LY912_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBM6955146.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15202..16623)
                     /locus_tag="LY912_001442"
     CDS             complement(15202..16623)
                     /locus_tag="LY912_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBM6955147.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16626..20015)
                     /locus_tag="LY912_001443"
     CDS             complement(16626..20015)
                     /locus_tag="LY912_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBM6955148.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20272..21663
                     /locus_tag="LY912_001444"
     CDS             20272..21663
                     /locus_tag="LY912_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955149.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21736..22383)
                     /locus_tag="LY912_001445"
     CDS             complement(21736..22383)
                     /locus_tag="LY912_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBM6955150.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22391..23077)
                     /locus_tag="LY912_001446"
     CDS             complement(22391..23077)
                     /locus_tag="LY912_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955151.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23083..24156)
                     /locus_tag="LY912_001447"
     CDS             complement(23083..24156)
                     /locus_tag="LY912_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955152.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24378..25052
                     /locus_tag="LY912_001448"
     CDS             24378..25052
                     /locus_tag="LY912_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6955153.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25057..26397
                     /locus_tag="LY912_001449"
     CDS             25057..26397
                     /locus_tag="LY912_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBM6955154.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26546..27532)
                     /locus_tag="LY912_001450"
     CDS             complement(26546..27532)
                     /locus_tag="LY912_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBM6955155.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8035 a         5224 c         5013 g         9323 t
ORIGIN      
        1 attaatttta accattctgt ttatttgctt acctattaga tatcaataaa aaactgctta
       61 acagctattt cagctgttaa gcagttttag gatttttagt tcatattcat tgtttcttat
      121 aatacagtgt tcaatacttc tcttaaagca cttgttgatt tgctgaacat tgctttttct
      181 tcttcgttga ttgataattc aacaacttca cgaacaccat tttcgtcaac gattgatggc
      241 acacctgtaa agatatcttt ttcgtcgtat tcaccagtta aataagcaga tacaggcaat
      301 acagcttgtt cgttattcaa gatagctttt acgatacgtg cagtactcat accaatacca
      361 tagtaagttg cttttttacg atcaatgatc tcataagcag cattacggac tttatcagca
      421 atcacatcta attcatcttg ggcaatacga tggtcttttt ctacaatttc aaacactggt
      481 ttaccaccga cagttgtatg tgaccatgca gcaacttctg aatcaccatg ttcacctaag
      541 atatagccgt ggacgctgcg tgggtcaact tttaatttca atgcgatttc tttacggaaa
      601 cgagttgtat ccaatgttgt tccagtaccg ataacacgtg atgttggcag accagattcg
      661 ttccaagcga tatatgtcaa aatatctact gggtttgaag caacaacgat aataccgtcg
      721 aatcctgatc ccatgatttc ttttacgatt tggcgcatga ttgacgcatt tgttttaact
      781 aaatctaaac gagattgacc aggtttttgg ttgataccag ctgtgataac aacgatatca
      841 gcatctttac attcttcata gccacctgac catacagcca cattttcatc gccccaagcc
      901 ataccatcta aaaggtccaa tgcttcccct tctgcttttt cttgattcac atcgatcaat
      961 actaattcat tagagattcc ttggttgatc attgcataag cgatacttgt tccaacaaaa
     1021 cctgtaccga cgattactac tttacgactt gtttttttca tgaataaaca gctccttttc
     1081 ataactattt gttactttca tgaaaagtat agtcttgttt attcatttta tcaacatgtt
     1141 aattataata gttgttatta taatttttga tggaaacgaa ttcctgaata cgcataacag
     1201 ataaatgaca aatgtttaca cctatatccc ctgataatac aaccaaaagt ttagaactga
     1261 aaataaatcc aaaaaaattc gctgcaacga tataataaga cagcaatcgc acctaaaaca
     1321 attttccttc atatgcttta gtgaaagatt ttcttcttaa tgtttatttc tccattcatt
     1381 gggagtacat gttgaatact tcttgaataa tttgaataaa gaagtcgttt gtttatatcc
     1441 gatacgatta gcgatttctt ccaacgaaaa actcgtttct tgaatcagtt ccaacgcaaa
     1501 gtcgaatttt ttctttagaa ccagttcttg aaaggaagca tcaaaataca ttttcaattt
     1561 attactaaga tagaccggat tgtagccaaa atgagctgct gtttctttta acgtacaaga
     1621 agtaaaatgc ttatcgatat aatctaatac tctaagcatc tcattttctg cgcatccatc
     1681 tgctgatgaa aagctttgtt gttctaataa atgagtcaat tcgatcagta atagtgatgt
     1741 atagagattt aacgaacgga tcttatgact gtatgtatca aaataaatca acagcatatt
     1801 ttcaatcaaa tgcgtcaaac gacttgtttt tccgccgcga aaatgaatga attgtgtatg
     1861 ttcccctttt tcttttgatg catttatcaa aaaagaagaa agtagattat ttgtgcttgc
     1921 caaatgattc aatatctctg tagataaggt ttcttctttt aataagatgt tgattaaaat
     1981 atcctcttgc cctgtgtatt cgattctttg agtagcttct ttatcaatga tcaccacgtc
     2041 actttcttcc atctctatcc tttctccatt aataatttgt aaacatgtac cgctatacat
     2101 ataattgatt tcaacaaaat catgtgtatg ctcgggaact tccgcatatc gacggtgttt
     2161 actgatatga atatttccct gttgaaatag atcccctcgg tggatttttg gcggtgtctg
     2221 aagatggtaa gctaagttta aatcattgat attcattcct tgttcacgct gcagagtttc
     2281 gattgattct tcgttacgca aaaaaaatgt ctaattcagc tagttccaat tgactccctc
     2341 ctttttgtaa gcggtttctt tcgcttatta gttcacgctg tactgctatt atatgcaaag
     2401 ctatttttgg tttcataaag actttctatg gttgggacat gaacttcctg tgattccgct
     2461 attgagagaa taaccacttc atactatatt tttgataagc gcttacaaaa atgaaaggaa
     2521 catgcttatg aataaaaaga tgatgaaatt ttctctgctg tcagtctctc ttattttgac
     2581 ttctgctggt gcagtcacgt ctgcaattcc cagtatgtca gctacttatg ccacgcgttc
     2641 tttatctgct gttgaattat taacgactgc tccctctttt atggtcacta tttttgtttt
     2701 gattagtagt tttattgcta ggaaaatcgg acaaaaacaa actgtgatca tcggattagt
     2761 gattgcatcg atttgtggta tcctccccct cttctcacaa agttacagta ttgtcttagc
     2821 ttcaagagct ggactaggta ttggctttgg attgatcaat tctttggcag tcagcatgat
     2881 tgctgccttt tatcacggag atgaacgagc ctctatgatt ggttttcaaa gtgcatttca
     2941 aggatttggt gcagctttaa tgacatttgt tgcaggacag ctagtacagt tcggttggca
     3001 atataccttt ttagtctacg ccatcagctt acctattctt gtcttgtttg ttttgtttgt
     3061 tcctacacct gaaacaactg aacttcaatc gcatggcaca gccccaacaa gacaagtaat
     3121 caaaacgaat cctaaaatga ttagttatgg tatttttctc ttgctggtca tcgtggtata
     3181 taatgctgta tcgattaaat tagccacagt cctgacgact tattctctag gaaacgaaac
     3241 taatgcagcg aatatcttaa caatcatgca attggcaagt atggctgccg gagtttgttt
     3301 tggctggctt cagacaaaag cacatcgcta tatgcttaca ctttctttac tactgatggg
     3361 aatcggcttt gtattgattg ccactgtgat aaacctgtat gtgattgggt ttggtgcgat
     3421 cctaacagga atttcttttt cgttattcat tccttactta ttcaaccaag taagtatcca
     3481 agcgcccaag tacgcggaga gtttcaatac ttcaatctta ttggttggcg ctaatttagg
     3541 tactttcatt gcaccatatg gtttgctctt tctctctttt gcttctcttg ggagtaaaac
     3601 acttgctgtt ttcgtcaatg gcagtatctt gctgttgatt agcgcgctta ttagccttct
     3661 agtagtacac aggacgaata gaaagacagt gataagagta gatgaagaaa taaaagaaca
     3721 attgacaaca aaataaattt gatggaggtc gtgtaaaatg acaaatgaaa aacataaaga
     3781 tagatggctt tggtatcctg gagactttga gatccgccat ggactgctac aaaatttcca
     3841 acgggaagaa cgaggttttg actggccagc gtactggtac atggatgatt gccatcggaa
     3901 cgtcaagttt aagagatatt actttcttga tcaaccttcc atgtttaaag tgacgatcca
     3961 aggagttggg tatgtagaaa ttaatggaca aaaacatcca tgtggaaaat ggctgacttg
     4021 tccagctggt aaagcaaaaa ttcgtatctt tgtaggacat acatcagggc taccagcgat
     4081 gtttatcgag ggagacgaag taaaatcaga tattggctgg acagcaagta attttattga
     4141 agaatatcca gctggctgga gtccgcttta tgtcgatatc gcaaaagatc caaatcaaat
     4201 ctattatcaa aaagaatgcg tccatccagt cactgaaacg gagattggcg gaggaatctt
     4261 attcgatttt gggcgagcag tgaatggctg tgtagaacta atatctctgg atgaccatat
     4321 cgaatctatc actctatgtt atggagagtc cgatgtagaa gctatggata tcgattattg
     4381 ctactataag caaataggaa tgacaagaaa aatgaaagct cgtaaacgcg cttttcgcta
     4441 tttgtttata ccagaggttt ctactggaat ggttcaactt caagtttttc atgaattttt
     4501 atctctttcg aaacaagctg ctttttcaag cgattcttct ttactgaatc agatctggtc
     4561 agtatcagaa gaagccttca agttatgtag tgatttgttt tttatcgacg gtatcaaacg
     4621 agatcgctgg atttggtctg gagatgcgta tcaatcattc atgatcaatc aatatctttt
     4681 ttttgacgag gaaatcaata aacgaacgat attagcatta agaggacaaa atgaaatcaa
     4741 gcagcatatg aatactatcg ttgactattc gatcttgtgg ttgattggta tcgaaaacca
     4801 ctatatgatg acgaaagact atgaattttt acgcatcgtc taccctaaga tgcaatcatt
     4861 aatgagatac ttgatggagc aaacgaatga attagggttt atttatggga gagcaaaaga
     4921 ttggatattt attgattggt ctgaaatgga taaagaagga acgcttgctg cagaacaagt
     4981 cttattactg aaagcctatc attccatgat cacttgcgga gatatcttag ctgaaacata
     5041 tggagagaac gaaaattatc atactcatct ctatcaagaa aaatatcaac tattgaaaca
     5101 aaacctattt gactactttt gggatgaaga acttggcgct tttatcgatt gctatgaatc
     5161 tgggagaaga aatgtgacgc gtcatgcgaa tattttcgct gttttattcg attttgctaa
     5221 caaagaccaa cagcaatcga tcttaaagaa tgtcttattg aatgacacta tcacacagat
     5281 tactactcca tatttcaaat tctatgaaca agatgcttta tgcaaactcg gacagacgaa
     5341 tatcgtctac caaacgattc ttgattattg gggagggatg ttatctcatg atgcggtaac
     5401 tttctgggaa gaatacgacc ctactcaaac aggaaatgaa aagtacagta tgtatggaga
     5461 tccttatgga aaaagcttat gccatgcatg gggagcaagc ccaatctatc ttttaggacg
     5521 ctattttatc ggtttgtatc caacaaagcc aggttatgaa gaatttatga tacaacctaa
     5581 tctagattca tttgaaacac tgaattgtac gctacctatc aaagatggaa agatttcgct
     5641 tgaaaaaaca aaagataaga tcgtgattac ttctgataga acaggcggaa cagtgaaaat
     5701 gaatggtaaa agttatcctc ttctagcaaa acagccactt gtcttaacaa gctattcaaa
     5761 aataaatgca taaaacaaaa aactgcttgc gacatatcag aagactttaa atcttcttct
     5821 gatattgtcc aagcaatttt tattttgaag tttgcttaat tctgttcttt agaaacaatg
     5881 tttgttcttt ttccggcaaa aagaaagcta gataatacga caagtaaaaa gaaagcgatg
     5941 attccaactg tcaaggctat ttgaccgtat tctcctagtt tcccaagtac aagtcctggt
     6001 actagataat cagtatcggc aaatgtagaa gaagcgattt taagatctcc taatactgga
     6061 aggataaata atggcagcca actaatcaat aagctattga aagcagaacc taataccgcc
     6121 cctcttctac cgccagtcga gttgccgaag acaccagaag cagctccgca gaagaaatgt
     6181 cctactaccc caggaatgat aactgtagtt tgcaagccta tcatagcaaa catggatagt
     6241 gttcctacaa agaagctaac aaaaaagcca attaatacag cattaggtgc atatggaaaa
     6301 acgataggaa catctaatgc tggtttagaa tcgggtacga gttttttagc aatcccttgg
     6361 aatgctggaa cgatttctgc caacaccatt cgaacccctt gaaggacgat aacaaaccca
     6421 gctgtgaatg ttccagcttg gatcagtgca aagattacag cgttgtctcc attgcttagt
     6481 tctctttcaa caaatccagg accagctaac aaagcaagtg cgacatatac gatcgacatc
     6541 aagagcatga tcgatacagt agaatctcgc aaaaagctga aacttttagg aatctttatg
     6601 tcctctgtag aacggtcttt gtttccaaaa aactttccga tccatccact agaagcataa
     6661 ccgatatttc cggtatgccc taacgcaact tgattgtttc cagtgatgtt cttcataaac
     6721 ggttgacaaa gagcaggcgt aatagttaat agtgttcctt cgaagacccc gcctaataag
     6781 atcatccaca aatttgcagt aaaccccgcg cttactaaaa tgactgctgt tagacaagaa
     6841 acataaagca ttgcttgacc tgtaagaaaa atgaatttat atcttgtgaa tctagcaagt
     6901 aaaatattca cgatcatccc tactagcatg atcaaagcag taggtgtacc gtattgttgc
     6961 aaagcaatcg ccactactgc ttcattgcta ggaactactc cttgagtatg cagagctgtt
     7021 tggaacatcg aagcaaaagg ggttagtgaa ttactgatta aaccagcacc gccgatcagt
     7081 actaggaatc cgacaaatgt tttgatagtt ccttggatca cttctgaaaa tttcttcttc
     7141 tgaagaacga gaccaagcag tgcaatcaaa gaaacgagga tggagggctg actgacgatt
     7201 gacacaaaca aattcaacaa tttatccatt gatagttcct cccttgaatc atttttattc
     7261 ttttgacaag atcttcgtta ctttttcttt tacttcttcg ctgtcaatga tcgattgcaa
     7321 aggtacgagc ttttcatcag gtatagaagt tagcgtatct ttcaaagaat gctcaatgaa
     7381 gaaataatca gccatatcgc tagatacact tccaacatcc gtatgactta cttcaaactc
     7441 gtccacatct gctccaagat ctgcaagtgc ttgtttgatg ttcatctcta ccataaaact
     7501 tgttcctaat ccactttgac atactgcaaa aattttcata tcattcgtct ccttttctta
     7561 tgatcgctaa tatttcttct tttgttgatg cgtgtaataa atcttgaaga ttttgtttat
     7621 tagaaagtag ctttgttaaa tttgccaaag cccgaagatg tgcctcatta tcgatagcag
     7681 ctaaacagat gaacaaacta atgggatggg ctggattatc aagcagatcc acaggttgtt
     7741 gaagtttcag caaagacatc cctacttcgt ttacgccatc ttctggacga gcatgaggta
     7801 atgcgatgtg atcgccaata tggataaacg caccatactg ctccacgcgc tcgatcatag
     7861 ctttgatata actttcttct attttatttt ctgataatag cggctgtgcg gcaaatgtga
     7921 ttgcttcttg ccagtttttt ggttgatccg ataattggat catttcttct gttaataatt
     7981 cagatagcat aggacgttga tcctccttct tttctaaaag tttgttcatt ttacgattta
     8041 atacttgata gagcttttct tcgtctacgc cttcttttaa ttcgatataa ggcagtagcg
     8101 ccgacaacaa ttcttgggca gaaggcattg aaaatcctgg tatcagccaa tctctttgta
     8161 cttgattgat cagctgattt ttttccaagt cagtcatgat tggatgcaga acatagagag
     8221 actttttctt atcagtaagt gtgagaggta cagtagaaaa aataatatcg taagaagttt
     8281 cgtcaacctc gtgtaagcgg tcagctgaat tagtctctgt aaaaaagatc atcgggaata
     8341 attgctgaag ttcacttttt aagatcaatg aagagctaat gccacttgga cagacgatca
     8401 cggctcttat ttttctattt ctttcttctg cgtccgcttt tctgatctct ccgccaaata
     8461 gtatagtgaa aaaaccaatc tcttcttcag ggatgctctt ccctattcgt ctttctaacg
     8521 gaagtaatgc ttttcttgtc atttcgtaga tggaagcata ttgatgctta atttgatcga
     8581 tcatcacatt aggtaaataa aaagaatagg aaatacgaaa ataggcaggg accaagtgat
     8641 aaaagacatt catcaataat tcacgaaacg aagcaaattc tacggccatc aggaattcca
     8701 tgcgatggat gacttctgaa gaacattcca gcaaaaaatc aagtgcaggc tcctggacat
     8761 ctccttcaac gatcgatgct aagcaaagag agaaaaatat aatctccgaa ttttgatgtt
     8821 cggaatagcc aaggccagtc aatacttgtc gactaatgtc agtgactgca agagaagcca
     8881 acagttcagc atcttttacc agttccatgg atgtttttcc aattcgaatg gttgtcaaac
     8941 tcaaataata agctaattca tccattcgat ttggtgcgaa tcgaagatct gatagtgaaa
     9001 tcgttttatc tagcaaatct ctaactttgg cgtaataatc aatggaaagg gttgcggtta
     9061 aatacgtgag cccaaatctt ccagcaagtg actgcatcaa acgagcagtg cgattttttg
     9121 cttctcttct taatattgct tctgacccta gcagcctaaa accagttttc ctagtatacg
     9181 acagctgaca atcttccact tctaattcat ttcttatctt tttgatatct gacaggactg
     9241 tccctttaga aacctgaaga aaatcttgaa aatgaaaaac agaaacagac gttgcagtcg
     9301 aataaaccat caaataaaga agatctcttc gctcttgttc ggtatacaca gcttcaaatc
     9361 gagtaatatc caaaaatttt tctgcccagt cgattgctcg gaatttcttt atacggatac
     9421 gggtatcatc cacatattcg gcaaaaggag ttaattgttt gatcgcctcg cttgtattta
     9481 cttcgatgat ctctgctgct ttttctagac tgatttctct tggtgttttc aggagataac
     9541 taattttgta gttcacagcg ctgttcacct cctacttata ttctagtatg gtagcgcttt
     9601 taaatcgagg ggtgtttggt acaacttaca gttggatttt ttttacgact gtaccgaacg
     9661 atttctatcg aatggataca gaaaaaaagc aggtgaccaa atgtctcctg cttttatgaa
     9721 ttgatttcgt ccgatcaatg atgatcatgt ttattttttg aggtcagttc ttcaaatttt
     9781 tctttgacat cttcaaccgc tttttcgata tctttttcaa agtgattggg ctcattaggc
     9841 tttgtttcct cttctacaga atttgaacca gataaagctg tttctttatt ttctgtttca
     9901 ccagagtttg tgccagctaa tgattcttct ttgtcttctg tttcaccaga attagttcct
     9961 gctaaagcca cttcttcttc tgttttaggg gccattgaac ctcttaatcg tttgtgtttt
    10021 tcaccgtcat aatttgtcat gttggttcct cctagtagtt ctatactttt tcatcgtaca
    10081 ataagacagt ttatgcgtca aaaaacaaac ccgattctta caaatatgtc atatttttcc
    10141 ttctgattct tgaatgcttt tgattccttc ttccaaaatt ttcatttgta agattgtttc
    10201 ttcatctttg atgacttttt ctgcgccatt aactaatgtc tcgtaaatcc cttcgtagac
    10261 acggctgtaa tcaccaacct cggaaattac tttttcttca tgataactcc cttgttcatc
    10321 tatataggtc aatacaccat aatgttcggg caaatcgata ccaaagtctt catgatcagg
    10381 catgtaaaac attttcagat gttcttcttg tcgatctttt gtttgtttca cgaacatccc
    10441 tttttttccg taaacgacga aacttggacg ttctttgatg cggaaataac tggattttat
    10501 cgaaattttc atatttccat agaaaaaatc cagatcgaag taatcattca ttcgtccttt
    10561 ccctaaaagt tgacgtacat catagctgat atcatctggt tcgccgaaat aagaaagaac
    10621 ttgatctact gtatgacaag catgtccata taaatagctg ttcgcagtag aaaattcatg
    10681 cgtattttct ggtacttccg gtctgaaata atcataatgc atttctactt ctaaaatatc
    10741 ccctaatttt ccgctttcga ttactttttg gactgtcaag aagtcagaat cgaaccgtct
    10801 gttttggtaa cattggataa atagaccttt ttcttttgct aatgcaaata actcttctgc
    10861 ttcctttgac gtttctgcaa aaggtttctc tactagtaca ttcttaccat gttcgagtgc
    10921 catttttcca tattcataat gaaattgact aggtgtagtg atgacaacta attggatctc
    10981 aggatcatcc caaagatcag acagctgatc agtatattcg atgtcttcga atgttttcca
    11041 cactggttca gatggggaaa aaattttttt gatattgatt ttgttcgtaa gttttcttga
    11101 aaaaggcaaa tgatagcgat ttgtactctt tccattgcca agataagcga ttgtaagcat
    11161 gagtggtgcc tccttttatt gatgttttca gtatatccta gaaaagcgca gaaagtattt
    11221 ataatagcta ttctggtaaa aaagttcaga aaaacacttg ttatcattcg gtttggtgaa
    11281 attaatgttc aaagtaagga taaaaatcaa aaagatagta gcggaaccaa gtgtttatca
    11341 gtaagataga atttggaggt cagatcatgc ttattgaaga aaaactaaca aaacaagagt
    11401 tgtttaccac gacagagaaa cggattgtcg attacatccg taggaatatc gaagctgcag
    11461 tctacatgac gattgaagaa ttagcaaaag ctacgtatac ttcccattca gctatcattc
    11521 gtttatgcaa aaaaatggga ttcagcggat ttaaagaatt ccgtttcgag ctggggcggg
    11581 aagttcatca attgattgct cagttcaatc aaacgattga tcctaatttt cctttttcaa
    11641 gtgaagatag cactcagcaa attgcaaaga aaatggcgga tttatcgatc cagtcaataa
    11701 aaaaagcaca attgcagatt gaacatgaag atttagatca aatcggtaaa gtattgaaca
    11761 aggcacagcg aatctttctt tttgcaaaag gtgattctca aatcacggca aggaaattcc
    11821 agaataaaat ggtcaagttg aataagtttt tgatcatggc tgaagaatac agtgattctt
    11881 cttggaatgc agccaatttg actagcgagg attgcgccat ttttattagc tacagcggtc
    11941 gcatccatca ttatgaacga ataatgacct atttgaagca tgtagaggcc cctaccttgc
    12001 tgattaccgg aaatcagcat tcagaaatgg ccaaacaggc tgatatgtgt cttgttatat
    12061 cgcaggagga atatgatttt gctaaagtag cgactttctc ctctcaaatt gccttcgatt
    12121 acgtattaaa tacgttattc tcagtgatat attctcaaaa ttttgaagag aatatccgca
    12181 acttgaaaaa caaacaagaa ttgatgcaaa aaggccttct taaagaatat cggaaaactt
    12241 aagaaaagat cctcatttag taataagaaa gatagtgttt gataggctct ctttgatatc
    12301 atcataaaaa caggctgaag ttttcttttt caaacctcag cctgtttgtt tacggaacga
    12361 ttcgaataga tatattatag aaatgaggaa tagctaactt ctgtttctta ttttgaacga
    12421 ttgacgaaaa agatatataa gaaggaggaa aatcagtata catgcagcta acaatccata
    12481 caggaaaaat cgtttgttct cggatacttt ctgtacttct ttttgaactt cttttgcatg
    12541 ataaggaacc cggtgccctc tgacaagtaa gcgatgactg ttgaccatat aaggtgtaca
    12601 agttaggagt gtcacgaaat cctgcccttt ttcgattctc agatcttttg tatcagtcgg
    12661 ttctaccgtc ttgatctgat cgacttgata agcgagtgtc cgtccattga tttcgatata
    12721 gaaagaatca cctaaagtca gtttcggtaa gtctgtgaac aactttgctt gaggcagtcc
    12781 tcgatggctg gaaataacgg catgtgtatt ttctcccccc gtaggataag acgttccttc
    12841 caataatgag gcaccttttt ctagcagcac agtattcgtt tcatcaaaaa ttggcaaatg
    12901 gacattgatc tcagggatcg tcaaaatacc gatcgtatgt ttctcaaaat aggttctatc
    12961 ctttttcgca ggttcttttt tcttagtaaa gggatctgca cctggatttc caccttcttt
    13021 tgctaattgc tggtttttct ttgtcatgtt ttcttggatt ttagccatga cttcttcatt
    13081 ttctttgacc gcttgttgct gataatgaga gatgatctgc tgatccagat aattattcag
    13141 cgcgtcgcta acaaatggat aagctagtat ccctattcct gagagaagca agaaaagcat
    13201 cagcagatct agaagtttcc ttttctttgg tttcatttgt gttctccttg tgatgactgt
    13261 ttgataataa aagaaaaagg agcatttgcg taatccgctg ctcctttttc caattcttgc
    13321 aaaaagacta aatctgactg tgcttgcgtc tagcaaagta cagtccagca atcagtagaa
    13381 ggactactcc tgcaccgata tacacataga ttcccttacc gcctgttgaa ggaagtgtac
    13441 ctttgtgttt atttggtatt ttttcaggag aaatcaactg tcctgctgtt acataagatt
    13501 gttcatcgat agtaaatgct acacggtttg ttaatggaac atatttttct ggcgctttcg
    13561 tttcttccag atagtacgtg ccatatttta gacctgtcac atcgattaaa ccgttacttg
    13621 tggttgtaaa aaccgttgct gattctttcg ccgataccca gctgacggct tttgtggatg
    13681 ggtcgatcga taaatatttc gctgtgtcac tatcttgatc acgaacgacg aattctgctc
    13741 cagcaagtgt ttggtctgat gtaacgtcac catctacttt aacaaatcgt ttgcccccag
    13801 taacgacatc gactgacggt ggtgtttgat catttgtatg cccgttatcg acatttgctt
    13861 ggttagaaaa tcctttggtt ggatctgctt tttcgttcaa atgcatatag taaacgaatt
    13921 tcaatgtacc gccaggagtt aatgaaggaa tataattcgg atcaactgaa accgtgaatc
    13981 cgtctgtttg ctcagtgaca gaataattta ctgggtcgat ttctttattt ccatcatata
    14041 aggcataagc atacgttcct gaagaatcat tatcaaatgt taaagcagcg tcatgagtat
    14101 cgataagttt gaatgttgtg tacttgtttt gcgttccttc tttatcagcg atacctaatg
    14161 ggatattgac agaaatctca tattgaattt tttcaccgat tgcgacatct tttccattca
    14221 attgaggtgt tgttttatca actttagacg tatcattttt gatggtcttt tctactggtg
    14281 tttggctatt tgccaggatc tcaaaaggcg tgattgtttg cttttcaatc atttccgcat
    14341 tatcaggagc ttttacttct tctaaattat attttccaac ttctaaatga ttaacgatca
    14401 actggccttt ttcaatagat gcctcggcaa agtcattgtt gccgatgtca taagaatgac
    14461 cagtaatgaa atgtttggct ttggtttgat cagttgtcca agtgtacaat ccatctgtga
    14521 cactttggat gtattttttg acgcttggtg ttccttcttc tttagaaata ataaattctg
    14581 ctccatttag tgcttcgttt tcggcagtac cgatttttgt aactttcaac gttccatcat
    14641 taccgactgt atttttaggg tagagatgga tagtatctag ttcttctgtc ccgtatttat
    14701 aagagccatc tgcttgtttg atcatctcat atacagggaa agctaaaacc atgtttgcgg
    14761 cagctgacac tccgtctttt ggttcttctt tgatcgtgta gactgcatct ttcccatttt
    14821 gttttttagg taaagataaa gtgacatttc catcagcatc tgtcgttcct gaagcaactg
    14881 gtgtaccagg agtcaaagac tggactgctt gttttgctgc atccacggac gctcctttat
    14941 ctcgttgcgc ataaaattct tgagtgacgt tataaactga aaatgaaata tcggctaatc
    15001 cttggtattg atcgaattcg ctcatttctt tcccgctgtt ttggattaaa ggatcgggta
    15061 aatcagtcat tttcttttta tgaaggatga cttgagctgc tgtctcctct gcaaacactt
    15121 tttttgcgcc gaagctgttt gtgagtaatg gtaaaataag gaaaaggact cctaacataa
    15181 cgtttatttt tttatgattt ttcatttttt cactcctgtt ctttttttga taaacaacca
    15241 gattgcaaag cttgcgaata ccataccaac aacgcctaaa agtgtatttt tcgtttcgtt
    15301 tgtttttgga agaaatggac ggctattttc ttttttattg actactttca atatactgtc
    15361 cgcctcttta tcctcagaaa gaaaagttga aatggtaaac ggaatttctg tttcacttaa
    15421 aatataacca gaaggtgctt cgatctcttt taatcgataa cttcctgttt tcaacccgga
    15481 aattgaaaaa gcgccatttt tatcggaaat caggtgaagc gcatctgatt cgttctttgt
    15541 ccacttgtat ccgttggctg tttgctggag gtaatttcct gctttgtttt taataaggaa
    15601 tactgcgcca gctaatcgtt tatctggttt atttgtctcg attttgacaa attgcttact
    15661 ccctgtatat acagagactt tctttgtact gacaccaaaa ccaaaatcca gtgttccgtt
    15721 gttgttgatt tccttgttcg cctgtgctgt actgcttagc tgcatctgat aagaaatggt
    15781 cagttttttt ccagcatatt tttccaacga agggatcgaa aataaaacat caaatccgtg
    15841 aggtttcttg tgtatgacaa agccttctgt cagcttttct ccattcgatg aaatcgttaa
    15901 actattaggt aaaaacgtta atgcttcatc cgcactatct gacaattcga acttttgata
    15961 gtcaaggata tttacaggaa ttgtcgtatg caaggaataa gtgatttttt caccaatcgt
    16021 aaaatcattt ctaggctctt ctaatacctt ctcaaaaggt ggatcagggt agtcgttttc
    16081 ttcattttta ggatacaaat ggatagttga aagtttttga ttgttttgtc catgtacagg
    16141 aagaacaact accatattct ctgccttttc tttgacgact tctggtactt tggattcaat
    16201 gaaaagatac gctttatctc ttttttcttg atctttagcg gccagagaaa aagaagcgat
    16261 accatcttcg ttgttaagag ttgtagttgt tgcttctgcg gtaaacatac cggaagacgc
    16321 accgtttttt gcgatctctg cttgtgcttc ttctaccgtt ttgccctttt cccgtagatg
    16381 gtaaaaagaa tctgtgacat cataaacttg gaatgtgaca ccatttaatc ctcgatacgt
    16441 ttgtaataaa gctttttctt gtccgtcatt tggatgattt ttcggcagtt gcccgtttgg
    16501 gaaaagcaat ttgtgtaaag taatctgaac catttctgtt tctgtttctg ttgctacctg
    16561 agtaaaagct ggtttaaata gtaacaagaa gagacacata ctaagccaac caagtttttt
    16621 catatttagc tgccccctct ttcttttttc aaaaaaagat accaaataga aaacgcacaa
    16681 ccaatcatcc ctactagata gattcctaaa cggccaattc ctcccgtttc aggtaatggt
    16741 acttttgcct gattcgtgat gtctaaagaa atctggttgt ttttggctcc tggtgacaga
    16801 acagattcat gatcttgtcc atccacttga attgacccat cttcgtgtat aactatagta
    16861 actggctctt ttagaccttg gtatccttct ggtgtaaaag tttcggtcag cgtataagtt
    16921 ccaggtttta aattttcgaa tagaaaggta tctgtttctt gtccatcttt tggcgattct
    16981 aagtccattt ctggtccctg cagtctgaat tttgctcctt ttaatgtctg tccgttgtct
    17041 tcttttttgt gtaccgttag atcaaacgct tttagtcgat tttgatgagt gagcgtccat
    17101 acattatttg tcatctcggt attttttccc gtgtaaatga tttttccata tttatcgatt
    17161 tggaattcat aatttcccgg cgaagtatca tatccggcag gaccagctgt ttcaacgact
    17221 cgatatttac caggtgtgag tgaatcaaaa ctggcaagac ctttttcatt cgttgtttgg
    17281 ctgtcaattg gctgataagt accatttgct tcttttttct gtagggaaaa tgctgctcct
    17341 ttaagattta tctctttgtc cgtcccttgc atcgcatact tacgtactgc tacaggaact
    17401 tcaacaaaag gattttcaat agtcaactgg atcgtatcat cggaagtagt gactgttttt
    17461 ccatcaatgg ttaccgtacc atcagaagcg atcttgattt cccaagtagt ctttttgctt
    17521 aatccatgcc cttctggagc ttttgtttct gtcagcgtat aggtcatttc tttttgcaat
    17581 ttgacatttt ctggaagaga ataggttccg tcgccatgat ctgttagtaa agtatcaata
    17641 gaatctcctg ttaatttgaa aacagcgcca ataagatcct tttcacctgt agaggaattt
    17701 ttcgttattt tcaagtttaa cggtgtgaat tgtttagtat ttttccatgt cattgcatct
    17761 atttgttgag aatcgtatcc tggtacaggt aattctttga ttgtttggta actgaatgct
    17821 tgaccttgat tattgtattg aggtagtgat aatatctctt gataactttc tccgctattt
    17881 gcagataatt tgtcaatgtc tgcacgttcc cacgtatttg ttgtatcttt agctggttta
    17941 atgattcgaa tatatccgtt tttccaagct gcagcatttg tcgtatgttc ccgttgaatc
    18001 tcaaaagtaa cttgatctgg acgatcagct agattgttgt caaattcttc ccataacttt
    18061 ttgatgtgaa gactgactcc gggagcttta gcagatggta taccgaattc agctaattca
    18121 ttggtatcaa tgtttggctg gaaagttgtc ctgccgttca tttgatacca gaaatttgga
    18181 tggaagtcct cattttctgt ttggattctc acttggtaat ggatttggat ttcttggtct
    18241 tttcctaaat agatctgatt gctcttgatg gtatttcctt ctatggaaat agatggagtg
    18301 accgttgtag gacttgtccc cacactcttg actgaaagtg taccaggctg ataaatgaat
    18361 ggttctgcga ttggatcatt tatttgtcca ttgcttacag ttgctgagat ctgtacagct
    18421 tttttggcta ggtattcaga gatatctgtt gcatgatcag ctgattcata gtaaagatcg
    18481 cctttttcat ctgatgaaac catttgtcgc atacgagact ctacttctgc ttttgagaga
    18541 ccagctgccg gatcgctttg aagttggatg ccaagaccat gtatttcgat tcctcgttct
    18601 ttgagtgcca tcgcttctcc gatggttgcg ataaacgtac tgtcgattct tctggataga
    18661 ttgttttggt caggtgcatc atagattctt gagattagag aagtatttcc cggccgatct
    18721 tgcgtattag aaaactgagt tccgtaataa ttgctgcttg attgtgcgtg tacccgctgt
    18781 actttatagg aaaatgttgg tacaccatcc gtcagcaaaa cgatcacttt tttatgtcca
    18841 tttggaacgg atagcatgct tcctgcatct cttagtgctt tttgtgtaaa agtaccacca
    18901 tttgtccgtg aaggtgtaat ggattttact tgatttttca ctgaatcaaa tgaacccatc
    18961 tgtactgcac cgttactgta gctatatcct tcgcttgagt agccgacata tcccatattg
    19021 attttgtctg tgataccgct atctgctaaa gtatcgacaa aacgatcgac accaatcttt
    19081 acttcaccga tccgattatt gtcgttcata cttcctgacc agtctacgac caatacgaga
    19141 tcaagaggcg tgatatcttt ttgtacattt ccacgagcat tcaaataaac atcaaacaat
    19201 ccgggtgtac ttgtttcctt tgcatacttt cgtatcgcat agtctgcttg attaccggtt
    19261 cctccatatt cgatatacga atgggtccga tcattaggat ctccattcca agaatttata
    19321 ccatcccatt gatttgttcc gtttttattg ccttgatgat caagaacatt tgtatttcct
    19381 gtaggttgcc aactggcttt aggataagtg ccctgatcat ctgttgtata ttctgtagga
    19441 atcgtttgat tagatggcac actcacagct ggcaaggata atgtaggcaa tgtaaatggg
    19501 ctgacagaat tttcgttttc ttttgatgat tcttcttcta tttcgtctgg ctttggtact
    19561 gacacatctg tatctttctt attttctgtc tcatcaataa tgtcatattc tttattatcg
    19621 acgatcagct tgtttgcctg gctgtggtaa agtgctggat cgattggaaa actcagatcg
    19681 atagtttgtt tagtgtttga tgagatttcc aacgtaattt tcccgctatt tacctgataa
    19741 gcatagccat ctccttcttt tctttccaca tcacttaagt aattttcgac tagaccaatt
    19801 tctttttcta tcttttcagc actggtgtta ttcgcattta gcttgatgtt cagtgctttt
    19861 tttccagact gatccgaaat gacttcagct gaaattgttt ctaaaactgt tggatcatct
    19921 gtagtgtctg ctattgcaga taatggcaca aagtttgata aactcaatat tatcagcatg
    19981 aaaataactt tcagtttctt ccctgtggtc gtcatttttc ccctcctttt tctttttttc
    20041 tgttttgacg tgaatagtga aaattattaa aataaacagg cgttacataa ttttatttat
    20101 tttaatatga taattattat acgaagggcg ctaaagggaa tcacaccaat tttcatacca
    20161 attggtttca tttatgaagt tgattccttc gattaatgag cgtttcattg aaagaaaagg
    20221 gttgagggag aaaaacatat gatcaggttg ttggaaggaa actatagaaa gatggaaaaa
    20281 atcattcgaa ttctgtccat ttctgacaag tggatgacta aaaaagaact tgccaaacga
    20341 attggtagtt cagaatctac atttgtaagg tatatcgaag agatcaaaat ccgctgggga
    20401 acggatgtaa cgattcaatc ttcacaaaaa ttggggtatc gtcttgaaca tttgaatgta
    20461 ccagcttatt taaatgttct gatggaaatg tcgcaaagtt ctacaaacag tcgtttatta
    20521 aatgagatta ttgtcaatcc gggtaaaacg attgagtatt attgtgaaaa aatttccatc
    20581 agccggtctt cttttacacg taagttgaaa caatgcaatc aaattttaga aagctattta
    20641 ttaaaagtga tcgttgacca aggttttcag ttaactagcc ttaaaagtga gctccagttg
    20701 cgtatctttg ttaccttttt ctttttaagt tactacggaa gacgcacgtt gccatttcca
    20761 atcgaaaaaa agaagatcaa agaaattatg gtcaagaata attgtcagat gaatttgttt
    20821 caggaagaaa gcccatatga gcaatctttc tttattatgt attttgttgt gcatctcatg
    20881 agagaatccc aaggaactcc atttgaatgg aaagctggag actcttatgt acagttgata
    20941 aatatcgata aaaaagactt cttaatcttg aaaaatctct taggaaaatt gaagtacagc
    21001 agctatataa aagtagtgaa ctattttgtc aatacgattt tttcagaatt ttcggagaaa
    21061 gaaaaaaatg aaatcagtga gcagatacga aaaaatatgt cctactgttc gttttcatcc
    21121 gctgattgca aagaaaaaaa cgaagaatat gttgttcaat tattaacgca aatttatttt
    21181 ttctcccgta ttttcccata cgatacgact catttgacga tccgtgcaac ttactttgca
    21241 cagcagatgc aacaccgcca gatacgtcta tatgctggat ttcgtgcaga acttcaattt
    21301 tattccactc tactgaatca gaatctgatt tattatttat ctagctatat cttttggatg
    21361 cttatcggta atcctgaaat tcaccattat acttctgata aaaaaatact gattatcagc
    21421 gacttaagtc ttcgacatag tcaatatatt gaagaatata tcagtgatat tcttgctgtg
    21481 cataaaattc actctgagac aactgctatt actgaagatc agctgtcgaa atacaatctt
    21541 ctcgagtatg atctgatcgt tacgaatcaa cccattttga atgcccatgt tcctcatata
    21601 ttgattgatg atagtgtgtc attcgcaaat gaagaagaac tcatccgctt attcgagtta
    21661 tgaataatca aaaaacagct atgtataaac caccctgata aaaatttcag gacaaataca
    21721 catagctgtt tctttttatt gtattccttc agcaatccaa cgagatttat agcgaaagtc
    21781 ttttaacaac tcttcttttg tccaattatt tgcaatgaga tccgtcaaag tgttcattac
    21841 gagggtcatg gaaaagtata ggaaactaac tgcttcttcc gacgattgaa tggagaaatg
    21901 attgattctt aataattcca gccatttttc gttcattgga gaatcagccg atagttctct
    21961 acgtttggtt gtctgctgat catttcgctg ggttaacaag tataaccttt gccaatagat
    22021 actttcgtga tctaagtcgc agcaccactc taaatatttt tcgatcccca aaaagaaatg
    22081 ttgtttgttt tcgctaatga attttaagat atcttgatgg actatgtgag aactgctttt
    22141 gatcgtatac aaataagcat cttccaaatc ttgaaaatat ttataaaaag caccgcgcga
    22201 catccccatc ttgtcaacga tttctgagac tttgacttgg ctgatgtgct gtgagcaaaa
    22261 tatctccagt aataggtcat cgattctctg tttctttgcg ttcgataaat tgaaaaaagt
    22321 ttcttttggc atccacatct ctcctttatc tctgattata cgtggatagc ccttcattgt
    22381 catgaaggat tcattccttc tttttctctt cttctgtcaa gtacccatct tccattcgat
    22441 aaacgcgatc actccattga atcatacgga catcatgagt aaccataata gtcgcttttt
    22501 gtttctcatg agcttcttta actagtaatt tgacgacttc atatgcatga tctgtatcca
    22561 aactagctgt tggttcgtct gctaagatca agcttggctc attatataaa gcgcgagcaa
    22621 ttgccactct ctgtctttct ccaccagaaa ggtctttagg ataactattt ttaagtgact
    22681 ggatatctaa agattgcagc aaggaatcga tttttgttga atcttctttt tttgaagtaa
    22741 cttggtcaac tagttcaaat tgttccttta ccgttaaaaa aggaatcaaa ttagagcttt
    22801 ggagaataaa tcctatttct ttaaagcgta aatctgctcg ttttttttct ggaagctcag
    22861 ttagtgagtg accgttgatc actatttctc cggaagtcgg tgtttgcaat cctcctgaaa
    22921 tggtaaggaa agtactttta cctgaaccag aaggaccaat gatgctgacg aattctcctt
    22981 cctttacata aaaatcaatt gctttcaaag ctgagacctt tgtatgacca gaaccaaatg
    23041 ttttggtaac ttttttcatc gttaatattt ttttcatttt tattaacctc ctattgctgt
    23101 aattgggtct actttggtta tcgtacgtat cgaaaacaat ccgcctagca ttgcgacaat
    23161 gatcaaaatc ccactatata gcaaccattg tgaccaaaaa acagcaaaag gcatcgcgct
    23221 tggtaaaatc agactagtca aataagcaaa caaaagagca agcagaacgc ctaccacccc
    23281 aacaataaag gactgtgcta ctaaagattt agcgatgaag aaatttttga tcccttgtgc
    23341 tttcattact ccaaaaatag cagtcttctg aagtgtcatc acgtacatga aaataccgac
    23401 cacggcagca accactaaga acaaaaagta tatcatcgca tttaaggtca tattttgggc
    23461 agaatagcca ggaatacttt caatgaatgt cccaatagtt aataactgta gacccttcga
    23521 tgctttttct ttcgaaattt tagctgaatc ctttattacg atcccattga tcggctgttc
    23581 ttcttcagaa gcaaacggct gttgtccata cttcaaagca gtccacgtat ctagggacgc
    23641 atagatgacg ggagaaactg tgtaataagt ttcaggaaag ataccgacaa tcgtcaaagg
    23701 atcgtcgtaa ctgccaattt tgatcgtatc tccaatttta tagcctgaat cagccagatt
    23761 ttgagagatg atgatttcat tctttgtttt aaattcatgc cctttcgtga gttttggtaa
    23821 taaaaatgct tctttcgttg tgccgaaaac tgtaacattt tctttgtttt ttcctttgat
    23881 tgctccgctg tacaatccga ttggtgcttt ctctcctcct tcaatgtatt tcagatctcc
    23941 tcttgttaat tgtgaagctg caaatacttg atttgcatcc tccgacaaaa caatctcttg
    24001 tgcgtcccaa tcatcgattg cttttttaaa ctcttctgaa agtccattcg ctagtcctga
    24061 caacatgaat acgacatacg caatcaagaa cataataccg acgatcaagc catatcgtaa
    24121 tttagaatag cgaatttctt tgatagctag aaacatttgt ttttcctccc tatgatagat
    24181 tgatagtgac aaaatgtcac ttgttgaata gtgtaactct aaagtgacaa tttgtcactt
    24241 gtgttgtttt tttcttatca ataaattgtc taagacatct ttcgataaaa ccttaacatg
    24301 agtcataaaa aatttattta agccttattt atgctttcca tgataaacta aagtgaccaa
    24361 atcaatgagg tgggaaaatg attaaactat tagtagtaga agacgataaa gtattatcca
    24421 ataatataaa agaaatactc gctgcaatcg gcgagataac acaagtttat gatggtagtg
    24481 aaggactgtt cgagttggaa agtggagttt atgatcttgc aatcttggat ttgatgatgc
    24541 cggaaatgaa tggatatgaa gtgttagcaa aaatacggaa agaaaaaata cagactccag
    24601 tattgatttt gactgcaaaa gatagtttgg aagataagat tgaaggattt gaacgaggtg
    24661 cagatgatta tctaacaaaa cctttctatc gagaagaact gatcatgcgc gtgaaagcat
    24721 tattgaaacg ctcgctaggt ctctttgatg aaaatgttct gaagtataag gatatcagtt
    24781 gtgatttaaa aagcaatgaa gtcttgtata aagaacaagt tttgcccata caaggaaaag
    24841 agtttgaatt gctcgtttat tttttacaaa ataagggaat cattttgaca aaagagcaga
    24901 tatttgaccg gatctgggga tttgattctg atacgacgat tacagttatt gaagtttata
    24961 tgagcaactt acgaaaacat ctgcgaagta ctggattgga taaagaaatc aaaaccttac
    25021 gtaatgtcgg ttatatactg caaagggtgt gatgcaatga atggagatat tacacgaaag
    25081 caacgtagtc gcttttttgc gacaaatgta gcagcatttg cttttatctt ttttcttttg
    25141 ggattcatta ctttacagat attaaaccaa tctgcataca gagaaacaga tctgtcatta
    25201 gagaaaataa attttgattc tcgaacagta caattagaga tacaaagata tcagcaaggc
    25261 gatccctttt taaacccgac tcaaacggaa caaaacagaa caaacatgga acagccatta
    25321 atggaaccat caaatgaccg ttttaacact caagtgatct tgtggtctaa aaatggtgag
    25381 atattgaata aagcagctat tggtgggcgt ttcaaccaaa tcaaagaatt aaaaatggat
    25441 acgaaaaatc tgaataccat ccaaaatatt gaattaaatg aagacagtgg ctcatctgcc
    25501 ctctctttcc gttcgattac gaaaaaagcg gagacgaatc aagatggcgt tgcctacatc
    25561 caaattttag aaaatacaaa tcaaatcaag aattcattag cgacttttcg cacgattatg
    25621 attttgtgta tgattgtttt ttggattctc tctattggta tcagttatta cttgtctagt
    25681 ctaagcatgc gccctattat tctttcttgg agaagacaaa aagaatttgt tgagaatgct
    25741 tctcatgaat tgcgcacacc gttaacgatt attcaaaata gtttggaaca tctttttacc
    25801 aagcctaatc atactattat tgaagaatcc gaaagcatcg ctcaagcatt gtcagagacg
    25861 aggcgcctca ctggattgac ttcggatttg ctgacaatcg ctcggaatga ttctgatcag
    25921 cagctgcttt caaagcaaat gatcaataca caagaatata tcgaacaact tgttaaacca
    25981 tttcaagaga tggccatcat agatggaaaa gagtttattc tccataacga tgcaacatta
    26041 gaagtaccaa ttgatgaaaa aaaaatccat caagttttgg ttattttgct ggataatgca
    26101 ttaaaatata cgaatccaga agataagatc attttggatt catctgttaa ccataaagaa
    26161 tggctgattc acgtaaagaa tactggccct tctatcagtg aagaagatca agcaaggatt
    26221 tttgatcgat tttatcggga agatcaatct cgggcgaaag agactggcgg atacgggctt
    26281 ggcttggcaa ttgcaaaaca ggtaatcgaa cagcatcatg gacagatttc tgtatccaat
    26341 tatcttccac aaggagtcga ttttaaagtc caattgccgt tgaagcctaa aaaataatgc
    26401 ttatccctaa aaaagggctg tgacaaaaat cttgtcacag cccttttttg ttgcgaataa
    26461 acggtgttcc agaagtagct tcttcggaaa taagccgaaa tttctttaag ctgaccactt
    26521 ctgtcacaac ctctttagct tacgcttacg attttttatt gcggtcttca atgtgtacat
    26581 caccgcttgt gtcaatatcc aattcttctc ggctaacatc ttctgtcact ttttcaacat
    26641 cttcatgttc ttctttatga atcccaactt cttcacgaat aactgtatgt ttgcttacat
    26701 ctacttgctc ttctttgatt gggatagtaa tcgtgtcatc ttccaatttt tcgtctgttc
    26761 cctgtgaaga ttgatctgtt actggtttgc gttcgatgac gatttcttca cgtttgaccg
    26821 gtacttctac cgtttcagta tcgttgacca catgtttgtg gatgtcgact tctccagttg
    26881 tcacatcatg tgtatttaca tctaattttt cttcttttag ttgaattgta tcatcatcta
    26941 gatttggttt gcgatcgatg tcttcagtct tgcttgtacc cattgtatca gtctcgccag
    27001 gtacgtccat cggatcagtt cctggtgtca tattcaatgg atccgttgta ttttgaaagc
    27061 ctgtcgtgcc acctacgtcc attggatctg ttccagtgcc agtttctaat ccagtcccca
    27121 ttgtgcttgc tgggctaaca gtatcttgtg tatccattgt atcttctgtt gtttctggct
    27181 gacgatagcc ttttactgtg atgacaaatt ttccatcaga aatatctcct ctatattgat
    27241 ataaaggatc attttctggt gtagccgtct cagaatcata ggtatcaaaa gaaaaagtat
    27301 cttttatttt ttcccataaa gaacggtctt cttcaccatc catccgattt tcatctgttt
    27361 caacatctat accagacaat ccgtcaaatc ctagtctaga tgctgcttca tcagtagtat
    27421 aaataacgat atcatctcgt tcataccctt cgttacgcaa ccgttcaatt actgataatg
    27481 cttcttccct cgtactatag cttccgatga ccgttaaatt tttctcttcc atgtaaattc
    27541 ctcctagcaa atagatttat gattggtata ttgttactta taaatttatt ctata
//
LOCUS       DAFKHN010000034        25733 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFKHN010000034 DAFKHN010000000
VERSION     DAFKHN010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.034"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            168..2228
                     /locus_tag="LY912_001451"
     CDS             168..2228
                     /locus_tag="LY912_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBM6955156.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2311..2880
                     /locus_tag="LY912_001452"
     CDS             2311..2880
                     /locus_tag="LY912_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955157.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3055..3861)
                     /locus_tag="LY912_001453"
     CDS             complement(3055..3861)
                     /locus_tag="LY912_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955158.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3999..5513
                     /locus_tag="LY912_001454"
     CDS             3999..5513
                     /locus_tag="LY912_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBM6955159.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5916..6899)
                     /locus_tag="LY912_001455"
     CDS             complement(5916..6899)
                     /locus_tag="LY912_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBM6955160.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6904..7551)
                     /locus_tag="LY912_001456"
     CDS             complement(6904..7551)
                     /locus_tag="LY912_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBM6955161.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7636..8268)
                     /locus_tag="LY912_001457"
     CDS             complement(7636..8268)
                     /locus_tag="LY912_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBM6955162.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8284..8835)
                     /gene="coaC"
                     /locus_tag="LY912_001458"
     CDS             complement(8284..8835)
                     /gene="coaC"
                     /locus_tag="LY912_001458"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBM6955163.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8832..9569)
                     /locus_tag="LY912_001459"
     CDS             complement(8832..9569)
                     /locus_tag="LY912_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBM6955164.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9566..10555)
                     /locus_tag="LY912_001460"
     CDS             complement(9566..10555)
                     /locus_tag="LY912_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBM6955165.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10813..11355
                     /locus_tag="LY912_001461"
     CDS             10813..11355
                     /locus_tag="LY912_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955166.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11372..12457
                     /locus_tag="LY912_001462"
     CDS             11372..12457
                     /locus_tag="LY912_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955167.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12469..13275
                     /locus_tag="LY912_001463"
     CDS             12469..13275
                     /locus_tag="LY912_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955168.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13276..14103
                     /locus_tag="LY912_001464"
     CDS             13276..14103
                     /locus_tag="LY912_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955169.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14100..15173
                     /locus_tag="LY912_001465"
     CDS             14100..15173
                     /locus_tag="LY912_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6955170.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15601..18297
                     /locus_tag="LY912_001466"
     CDS             15601..18297
                     /locus_tag="LY912_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBM6955171.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18374..18862
                     /locus_tag="LY912_001467"
     CDS             18374..18862
                     /locus_tag="LY912_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6955172.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18874..19368
                     /locus_tag="LY912_001468"
     CDS             18874..19368
                     /locus_tag="LY912_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6955173.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19389..20198
                     /locus_tag="LY912_001469"
     CDS             19389..20198
                     /locus_tag="LY912_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6955174.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20195..21016
                     /locus_tag="LY912_001470"
     CDS             20195..21016
                     /locus_tag="LY912_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBM6955175.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21067..23166
                     /locus_tag="LY912_001471"
     CDS             21067..23166
                     /locus_tag="LY912_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBM6955176.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23163..24281
                     /locus_tag="LY912_001472"
     CDS             23163..24281
                     /locus_tag="LY912_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBM6955177.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24320..25198
                     /locus_tag="LY912_001473"
     CDS             24320..25198
                     /locus_tag="LY912_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBM6955178.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25389..25541
                     /locus_tag="LY912_001474"
     CDS             25389..25541
                     /locus_tag="LY912_001474"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBM6955179.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8142 a         4473 c         5430 g         7688 t
ORIGIN      
        1 aattaaaaag tacataagtt attattccga ttttcttgaa acaataaaaa atcaaaaaaa
       61 atactctcct aatagtccat cttcttttga ttttatttat ataatgaaat catcttatga
      121 aaattactac ttcatgttta gacaagagta gggaggacta agaataaatg tgttcaaaaa
      181 gacgttcaaa acaactaaat aaacacgctt gtcgtttaga taaggaacgg tcgtgttctg
      241 aaaaacacta cgttaagttt atgatgcgca cgatgctgat cagtttatct gtaggtgtct
      301 atatgcatgt acccgttcag gcaacgacac aaaccatcaa ggtcgtacgt acctctgttt
      361 ctgagaccac tgattcccct atcactatta ctcatacttt cactgatgca aatggaaaac
      421 agctacttcc tgcattgact tcctataata aagtcagtta tcctccaacg ataaaccact
      481 actggttaat tcctaacaaa acattatgga catcggaaac cggaagcagt gtgccgcttt
      541 ctatcttttc cgatatgact gatcctacaa aaggtgatca gttaaaacag atcactgata
      601 ttttgaatca tgctttgaca gatataaagg acggtggaag cgcacaagtt tcttatgtat
      661 atgaaaaaga ttattcacag tttgaaagaa agaaaatcga tgttctggca gggacaaaag
      721 tttcgatatc tgatctggta gaaaggctga agaacgcaga tggaacacaa ggagatatgt
      781 ccaaagtaat ttcaaacaat gggaatatcg tggatacgac taatacagga acatctacta
      841 tttccttgtc ctattttgat ccaattgctt taaaaacaat gactgcatct gctgtgatcc
      901 atgttcgtgc tgatcaaaca gctatcaaag gaaaagatct tcacttaaga acaggagaga
      961 gttacgcccc taaagatctt gttgaatatg taacaaaaag cgatggaact tcaggaaata
     1021 aagaagaaat caaaatgaac gggacagtag atactacaac tccgggagaa tatcccgttg
     1081 tattaactta tatagactcg aaaacatcaa atgtggcaga aacaacagct gtagtttatg
     1141 tagaagcatc tgctgcttca tcgactgtca tcactcattt tatagatagt caaacaaata
     1201 aagaacttca agcagaaaca catatgagta gtgtaaatcg tattcctgat ttgcgcctac
     1261 ctgctgaatt ttctgatcga gtgccaaata tagatttatc gacttatgaa caaaatggga
     1321 aagtcacttc tatttctgat tggatgcaag caaacggatt agacagaaaa agtcactggt
     1381 cggagatcct tgaagtactt cactcagaac tgatgaataa taggaagcaa tcaggagggg
     1441 aaattacctt tacttatgtt tatataccag acaatcgttc attagaaggt catgatctta
     1501 ttgttcatcc aaacgaaaaa ataaacaaag aagagttgat ccaatcagca acaaattcct
     1561 taggtaaacc cgtaccgtta aaggatgtat cggttacaat caatgaagta ccattggagg
     1621 atggttattt gaccaaacaa acaggtgatt ttacgattat gtatagttat catgacccgt
     1681 attcactcca agaactccat gctcagtcac tattacatgt tttaccatta aacaaacaga
     1741 tagatcaaaa agaacaaaaa agacaagaag aaagcttgtc agaaaaaaaa caacaaatgg
     1801 cccatgcagt ttctccaaca gggaaagtaa aacaaacaag aagcctagag ttagcaagaa
     1861 tatctagaaa aatctcagaa tctaataaaa cgataaggca agaagctcat ttggccccac
     1921 aagtttctgg attggaaaat gaaattttag agcctaaaat aaaacaacaa tcagaaaaag
     1981 aatttgttgc taaacagtcg gaagatcaga aggaatcaga tgaccagaag gaaacgaaga
     2041 aaaaacgctt gtcaactatt gattccaccg atgagcatct gcagccgcaa gtaccacttc
     2101 ctagtccggg aacacccgca cctggtggag gtattccttc ttctgcttta ggagatttca
     2161 tgcgaggtat ggcaggaaca tgggtatacg ctaatcgaaa tgaatttgac gcagatgact
     2221 ggttctgatt tatatctcta tctgttatag tcaaataagt agctgagtca tatgttattt
     2281 ggcataatgg agacgaggag ggatagaaaa atgttagata aaacgttacc ttacgcagaa
     2341 atctggatga caagaccact tcaacaaaat gttccaatca cgcctttagc ggaaggtttt
     2401 gaatttcgat tttatcaaaa agaagatgaa tctgcttggg cggagattga gacttccgtt
     2461 ggggaatttc aaacgacaga tgaagcactt gagtattttc aacaaaactt tgctccttat
     2521 cctgaagaac ttgaaagaag gatgtttttt gtagagacaa aaaaaggaga aaaagtagca
     2581 acctgtaccg cttggcgaaa aaaatcaaga gagcaagtgt atccggtttt tcattggtta
     2641 gcagtgaaac cagattacca aggaaaaggg ctcgcaaaag cattgactgc cagagtcttg
     2701 caagaatttc ctaccctcca tacggacgga ccaatctatc ttcacacaca gacatggagc
     2761 catcaggcga ttgctcttta taaaaaaatg ggttttactt ttattgctga aaatctagac
     2821 ggcacaccta atccagatta tgaaaaagtt atgcaggttt taagtaaatt agataaataa
     2881 cgaaatggtg aaataagtcc tcagtattgg gataaaaaac gaaatagtca ttcctcatat
     2941 cttacttttt tgagttaata ctatcggata actaatggca tgccatacat tcaaaaaaga
     3001 aggggcagtg acaaaagtat tgtcactgcc ccttctcttg ttttttagca tgttttatcg
     3061 tttgattttt ttaggaataa aattcttgat gaacgtaaat ttttggtaat cgtttcgact
     3121 atagaggtaa ccaaatacac tgaaaacaac tgctccaata aaattaacaa ataaatcctt
     3181 catagtatcc atgattccca cgtctaagta accattttgg atgattgttt tatctgtttt
     3241 accatctgca ttttgacttt caatgattgt ccgagtgata tctggaacat gatagacagt
     3301 gtttccgtct ttacttaact ccacactatt gatttgctgg atgatcgtat ctttttgcat
     3361 atcgaattgc agtaatttat ctgctgaaaa ttccacaaac tcccacataa caccaactgt
     3421 catcgaaaaa cagaaggaaa caactgctag taataaagga gtcaagttca tggtttttgt
     3481 atttttattg agcaaataaa caagggaaaa gccgacaccc ccagctaaaa atccgctgaa
     3541 tgcatgtaga aaagtatccc acattgaaaa atagccataa aaatcactta actctcctaa
     3601 aactgttgaa ctaaaaataa aagataacaa aatgatttct agcatatttg gaatctgtat
     3661 ctttaatatc ttttccagaa aataagggat ttcaaataaa attaatgtca gtaataaaag
     3721 cattgtattt ccccagtgtt ggttccagac ctgatccact agcataataa cgacgatgat
     3781 acgtaataaa atatagattc cgtttgtgat tctacctgca gtttttgtac tgttcgtaaa
     3841 aaaggttttc aaatgattca taaaataact ccttcatgta tatccttaat tatactaaga
     3901 agcgtgtgtt taccaaagct atatgactta aagaaaaaca gagttgatat tgtgaaaaaa
     3961 atcacttaat atagtataag gagaaaaggg ggatacaaat gaaaaaatta gttgctggtt
     4021 tattaacagc cgttgcactt cttgctatga gcgcatgcgg cgcagatcag aaaaatacag
     4081 cgcagacaag ttctagtacg aaggaatctg ccgaagtatc atcaggcgct tctgaacaag
     4141 tatatacaga tccaaaagaa atgaaagaat cttatgatgt cgtgattatt ggagctggtg
     4201 gtgcagggat ggcagcagct atcgaagcaa aagatgctgg gttgaatcca gtaattttgg
     4261 aaaagatgcc tgttgccgga ggaaacacat ctaaatcatc aagcggtatg aatgcttcag
     4321 aaacaaaatt tcaaaaagaa gaaggaatca aagactcgaa tgatgccttc tatgaagaaa
     4381 cgctaaaagg tggtggagga acgaatgata aagaaatgct tcgatacttt gtcgatcact
     4441 ctgctgatgc ggtcgattgg ctagatcaaa acggtatcaa actggacaac ttaacgatca
     4501 ctggagggat gagtgaaaag aggacacatc gtccgtctga tggctcggct attggtggat
     4561 acttagtgga ggggttattg aataacgtcc atgagcggga aatccctatt tttgtcaacg
     4621 cagatgtgac agacattaag aaaaatgggg aaacggtcaa tgaagtgact gtacatgttc
     4681 aaggagaaga accaaaagag gtcaccggaa aagcaatcgt agttaccaca ggcggttttg
     4741 gtgccagcaa agaatttatt gaaaaatatc gtcccgattt agctgattat attacgacaa
     4801 atcaagaagg atcaactgga gatggtatca ccatgattga aaaattaggt ggacaaaccg
     4861 ttgatatgga taaaatacaa attcatccaa ctgtgcagca ggatgagggg gtcttgattg
     4921 gtgaggttgt tcgcggagaa ggagcaatct tggtcgatca agaggggaaa agatttgtca
     4981 atgaaatgga tacaagggat aaagtatctg cagcaattac agcattgcct gaaaaatcag
     5041 cttatttgat ttttgaccaa ggcgtgcgtg atcgtgccac agctattgaa ttttatgacc
     5101 aaaaaggata tgtcacaact ggaaagacaa tggaagaatt agcagaaaaa atcgatttac
     5161 caaaagaaac actagcaaaa acagttgatg gatggaatac ggatgttgcg gagaaaaaag
     5221 atgctcaatt caaccgtgcc acagccatgg aacatgactt atcgtctccg aattattatg
     5281 cgatcaaaat cgcaccagga atccattaca cgatgggcgg tgtgaaaatc aatacgaaca
     5341 ctgaagtatt agataaagaa aaccagccaa ttagggggtt atatgctgct ggtgaagtca
     5401 caggtggctt acatggaaac aaccggatcg gtggaaattc agttgcggag atcattattt
     5461 ttgggcgaca agcgggcata caagcagctc gatttgcttc ggaaaatgaa tgaaatagaa
     5521 cgtaaataaa aagaggttgt gaaatcagcg ttttgagcta ataccgaggg tcagctgatt
     5581 gaacactgtt tagtgaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
     5641 caagtaaaaa cagcttctta tgtttttaac ttggttggac ttattaccgc agatgcaagc
     5701 ttttgaacac cgtttattcg gaaaaagagc gtgggacaaa agtaaagaac acttttgtct
     5761 cacgctctaa acacgtataa acggcggaag cagaagaaat tccttcggaa ataagctgaa
     5821 attcacaaaa atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg
     5881 cttctgtccc agcctctttt ttgatcagca tgattttatt cagttatctt caaaatgatt
     5941 tttccgatgt ttttgtttgc ttccatatat tcatgcgctt gtttgactgc gctgaattgg
     6001 aatgtacggt caatgattgg ccgaatcttg ccattttcta gaaaaggccc agctttttgc
     6061 ataaaagttt gtgcgagctc tgctttatac tgatcacttc taggtgtcaa taatgtacca
     6121 agcagttgga cacgtttccc aatcaataca ccaaggtcta tctcaggcac gatggtccca
     6181 cctagcatac caatcaagac ccaacgtcca tcaacggcta tagaagctaa attcttttcc
     6241 cagtaagaag cgccgatgaa atccaaaata acatcgactc cccgaccttc agtgattttt
     6301 cgtacctctt cttgaaagtc ttgtttttta tagttgatca attcatctgc accaagttct
     6361 ttacaaaagg cgagtttttc ttctgatcct gcagtaacga tgattttcgc gtgagaaagc
     6421 tgtctagcta attggatcgc tgctgttccc acaccacttg ctcctgcatg gatcaagaca
     6481 gtttcgcctt cttgtaattt tccaagccag taaagtgttt gataagcagt caaaaaaact
     6541 tctgagattc cagcagcaga aacatagtct agcgtatcag ggagaaggat tgcacgatcg
     6601 gcaggcatca cagcatattc ggcataacca cctagattga ctaatccgta tacttttgtc
     6661 ccaggagtaa aagtggagat atcactttta ttctcaacta cctctccagc tacttcgact
     6721 cccaaaatag ggtagggagg tttcaaagag actgattctc ttttcataat atctgttcga
     6781 ttgacagctg ctgtatggac tttgatcagt aattcgcctt gttttggttt aggaacaggc
     6841 acttcaattt gttctaatac atctacagaa ccaggatgct tgattgaaat ggcacgcatg
     6901 gatctattcc tcctttgccc attcttggaa tgctgtattc aactctttgc taccttcaga
     6961 aagtactaga gtcgtacgag aaatatccgt ttcttccact agagcggcaa gtacagcagc
     7021 aactgtagag cgagtgatcg tttttgatgc cttctcatta ggcttagtta attgaatgga
     7081 agtaacttct tcatcgttag tcaatgtgac tggttgaaga atgacaaaat ctaagttagt
     7141 tcgtttcagc cattcatctg cataatgttt agtaatataa taatctgtca tggactcagg
     7201 ccattttgct ggttcatctg cataaacagc actgaccatc agatagcgag agacatgcgc
     7261 attttcagct gcgatcactg ttttgattgc gccatccaag tctacttgca gaagattctt
     7321 tccttgagag ccggcagcaa aaatcaatac atcgatgcct ttgaatgctt cggtcatttt
     7381 ttccacggac caagttaaat caaaagagac atacgaaaca ttctcttttt ttactaatgt
     7441 ttgggaagca acatctctca cccctgcaaa aatttcatgg gaacttggag ctaaatcttt
     7501 tatcaggtgt cggccaattt gtccgtttgc acctacaaca aaaattttca tttggatcat
     7561 cctttcgacg tcaaatcttt ccattcaata gtaacaccaa aagagaaaaa aatcagagat
     7621 cggctacgat gactatcagt tagtaagaga agggtgcttg aagtatctta acaagacatt
     7681 gcatactgct gcagtcgcaa gacctgcgac gattccttca ggtataccac ttgtaaaaat
     7741 aaccgctaga atagctgaat aaacagcatt taaatttgtt ccgatgactt tggcataatc
     7801 ttgctggaat aaaaagtaga tcatattcat cactaaaatc gtattggtca atgaaccgga
     7861 aagtccagct aagaataaag aaacggaatc tgctttttgt ttcattagtt tgcgcagacc
     7921 tttataaacg aaataaggaa ccaccccaat caagatgcga ggaataaacg cgatcagcaa
     7981 ggctttccag cttccatgtt ctgttccgat gactgggata aacggagaaa agacaaaaga
     8041 caaaggtgtt tggataactg tgctacggat catgctgatc agtccaaatg taccgccaag
     8101 aaaagcacct agtcttggtc ctaaaacgat cgaagcaatg attacaggaa tatgcatggt
     8161 tgttgcattg attggaccga tagggataaa acctaaaggc gtaacagcta ataaaatcaa
     8221 aatagctaaa aacatcgcag ttaatgtaaa gttttttgta tttttcataa gtactccttt
     8281 tttctaagca tttctttcat taagagtcag catgacctgt tcgatgatcg tctgaatatc
     8341 agctaaggca ccttttccaa aatctccaca agctaaaaga gattctcttg gttcaatttc
     8401 ctgatagccg acagatctca atgtttccag attacgctga gtgatcgggt tttgatacat
     8461 attcgtgttc atggcagggg caatcaattt tggtgttccc actggaagcg ccattgcgac
     8521 tgttgaaaga agatcgtctg caatgccgtt tgctagcttg ccgataatgt ttgctgtagc
     8581 aggcgcgatg agaaacaagt cagcttgttt tgctagttcg atatgattga ttacctgcgg
     8641 atttgattct tgcatgacgt ctgtatggac tgcgcgcttc gacagagatt gcaaggttaa
     8701 tggcgtgata aaatgtgtgc tgcttttaga cataatcaca tctacctggg cacctaattt
     8761 gacgaattga cttgtaagat cagcgctttt gtaagcagaa atacttccag taacgcctag
     8821 taagatcttt ttcattttga ttcctccagt ctaattttct cagtaatcaa tgcagcaatc
     8881 tcagatttac tttgagcttc ttccactgtt ccatctttag ataagagata gccgtggtgt
     8941 gtctcgccat ggatttccgt caaatcattt gcgaaaataa aatcagtttt gttatttatc
     9001 agactatttt ttgcgactgc cagaagagat tcctttggta catctactaa tagtttgaaa
     9061 ccaatgattt ttgcttttgg ctgccattca cgtagataag aaatgatttt tggtgttttc
     9121 ttcaaaacga gcacaagatg ctcggtgtta gaagagatct ttgaaacagt ggtatctgtc
     9181 tgttcatttt ccgcaaacca attgtccagt tcttcttgcg ttgaagaagt gggtaggttt
     9241 tttgccagct gttcttctga aaaactaaaa gcaggagtaa aatcactgac tgccatactg
     9301 tggataatcg catcgtagtg ttcttttttc gttagttctt ctaattgtaa aaataagtcc
     9361 agtgcagatt cgatcgtata aatcgttata ttggagtgtc ttttcggttt cagtgcttgt
     9421 ttcgtagtca cgtaatcgat tgtggtatcc ggattggcag ctaaataatc agctaatgct
     9481 tgccctaatc gtcctgtcga atgatttgta atagcacgta cttgatcgat tttttcagtc
     9541 gttcctccag ctgtgattag aatcttcatt tatggtcacc tacatttact agtgttcttc
     9601 cttggtgtgt tccagcaagt agtttagatg ctgtttcagg caattgatcc agagtaatct
     9661 cttggacgac cagttcatct gcaatctgca aatccgccat ctgttgccat aaagaaagac
     9721 gttgatctat tggtacattg acagaatcaa ttccaatcaa ctggatgttt cgcagaataa
     9781 aaggcaagac agtcgcgttt agtttgattc ccccagcatt gccacataaa gctactgcac
     9841 cgttataaga gatcaatgga agaagactgc ttagctgctc gccacctact gtgtcgatga
     9901 catagtcgat ttgctgtttt cctaaagctt ttgttgtctc tggcagaaat tcatcaggtc
     9961 gtacgacttg caaagcacct agacttttta gccatgtgac agactcttct tttctggaaa
    10021 aggcaatgat tgactggaat cctagtttat gtaacagggc tatcgctgta ctgcctacac
    10081 cgccagaagc accagtaacg acaacttttt tatcggaggt cataccttga cggattaaag
    10141 cgttcacaca caacatagca gtaaaccctg ctgtaccaag gatcatcgct tgacgcagcg
    10201 tcatattttt tggtagagga actaaccagt ctcctggtac tttttgatat tggctataac
    10261 cgcctggatg ggtgacgcca agcccaaaac cagtagcaag tacaagatct tcttttgaaa
    10321 aacgtggatt gttactttgg acgacagttc cggataaatc aatccctgga gtcatcggat
    10381 atgttcgtat cacctgacca gactcgctca ttgccaatgc atctttataa ttgacatcag
    10441 aataggcaat ttttaccaag acttcatttt cagccaactc agtaaatggc agatcactga
    10501 ttgctgtatg gaaaacaggt tcctttatta cctgaaaaga tcgaaaagcg ttcattcgtg
    10561 agacactcct tttaaaattt tcttttatca taccataaag cctactcttt tattcttgtt
    10621 cttccgtaaa tttagacaaa aattaggtga aaaataaaga atcaaacaac tagaatttat
    10681 tccaaaagat aaagaaatat tcagcaaaaa aaattttaca aagggttgcc tttttcaata
    10741 aatttcgtat actaatacga gtggtagtaa acaggaagtt tactattaga aaacttcgat
    10801 tcggaggaaa ttatggaaat tggtgagaag ttaagaaatt tgcgcatcca aaagaatttg
    10861 acacaagaag aactaggcga acgcacagat ttgtcaaaag ggtatatttc ccagttggaa
    10921 cgagatttaa gttcaccatc aatggaaaca ttcttttcta ttcttgaagt cttaggtgtg
    10981 actccagaag aattttttca tcaagaagca gcgaatctgc aagtggttta ttcaaaagaa
    11041 gatcatacgg tttatttcga tgaagaaaac gggtatgaat tggaatggct cgtggctgat
    11101 tcgaatgaaa aagaaatgga gcctgtcttg ctgacttttg aaggtgcagg agaatataag
    11161 acgtttgaac cttcattatc tgaaacgttt atttttgtat tagaagggga attagagtta
    11221 agcttaggag agacggtcta tgtggcaaaa gcaggacagt cgatctatta tcaagcgaca
    11281 aaacaacatc aattaaggaa tcatctcaaa aaacgaacaa aagtattgat tgttgcaacg
    11341 caatcatatt tgtaatatag ggggtaaaaa cgtggggaaa ccaatcattt catttgatca
    11401 agtagtgaaa cgctatgatg atgaaacagt attaaaaaaa gtaagttttg agatcgaaca
    11461 aggaaaattt tatacactgc ttggtccttc cggctgtggt aaaacaacga tcctacgtat
    11521 tatagctgga ttcaccgaag ctacagaagg ggacatctat tttgaaggga aacggttgaa
    11581 tgatttgcca gctaataagc gacaagtaaa tacagtcttc caagattatg cactttttcc
    11641 tcatatgaat gtttttgata acgttgcttt tggattgaag atcaagaaaa tgtccaaatc
    11701 agatatcgaa aagaaggtaa aagatgcttt gcgtatggtc cagcttcctg gatacgaaaa
    11761 acgggagatt agtgaaatgt ctggtggtca aagacagcgt gtagcgattg cacgagcaat
    11821 tgtaaatgaa ccgaaagtat tgctattaga tgaaccgtta tcggcgcttg atttgaaact
    11881 acgtacagat atgcagtatg aactgcggga tctgcaacaa cgattaggaa tcacgtttat
    11941 ttttgttact catgaccaag aagaagcgtt ggcaatgagt gatgagattt ttgtcatgaa
    12001 taaagggaaa atcgtccaaa gtggtacacc cgtagatatt tatgatgagc caatcaatca
    12061 tttcgttgct gattttgttg gggagagcaa tatcgtggac ggtgtaatga tcgaagataa
    12121 tctagttgag tttgttggta agcaatttga atgtgtcgat ggcgggatgc gtctaaatga
    12181 accagttgaa gttgttttac gcccagagga tttgacgatc acgacaccag ataaaggaaa
    12241 actagtcgta acggtcgata ctcagctgtt tcgtggtgtc cattatgaaa tcatctgtta
    12301 tgatgaacag caaaatgaat ggatggtcca ttcaacgaaa aaagctaaag aaggaagcaa
    12361 agtaggattg gcctttgagc cagaagatat ccatgtcatg cgtttcaacg agtctgaaga
    12421 agaattcgat gcacgtcttg acagctacga agaatagggg ggacaagaat gaaaacaatg
    12481 cgcaggatct attccgtccc ttatattttg tggctcggtt tattcgtgat cgcgcctgta
    12541 ttaatgatca tttatcaatc tttttttgat atgaatgggc aattcacgct gaataattat
    12601 ctatcttatt ttacgtcggg gacatcgctt tctatgacga tcaattctgt atggtatgca
    12661 tttttgatca cgtttttcac gctgatcatc agttacccga ctgcttattt tttaacaaaa
    12721 ctgaagcaca agcaattatg gctgatgctg attattttgc ctacatgggt gaatctgctg
    12781 cttaaagctt acgcatttat tgggattttc agtgtgcacg gcagcgtgaa tcatttcttt
    12841 gattttatcg ggatcgggcc gaaacagata ttattcacag acttcagttt tctgttcgtg
    12901 gcaacgtata tcgagattcc atttatgatt atgccaattt tcaatgcatt ggaagagatg
    12961 aatccttctt tgatcagtgc tagtagagat ttaggcgcga atagctttga gaccttccga
    13021 cgagtgattt ttccgttatc attaaatggt gtgaaaagtg gtgtccaagc agtatttatt
    13081 ccttctcttt ctttattcat gctgactcgt ctgattggcg gaaatcgggt gatcacttta
    13141 ggaacggcta tcgaacagca tttcttggtt acacaaaact gggggatggg ttctacaatc
    13201 ggtgtgattt taatcattgc tatgttcatc gtgatgctcc tgacaggcga gaagaaaaaa
    13261 ggaggtcgct cataaatgaa aaaatttaaa tggtcgtatc tttatttagg gatcgtcttt
    13321 ttattcttat atgcaccgat cttctatctg attttttatt ccttcaatga aggaggaacg
    13381 atgaacagct ttacaggatt tacttgggaa aattatgaag ctgtttttga agatacacgt
    13441 ttgatcatta tcgtattgaa tacgttcatg ctggctttct tatctgcatt gatcgccacg
    13501 atcatcggga catttggggc tatgggaatc tattacacga aaaaacgacg tgcacggaca
    13561 gcgttgttga gcatgaataa catcttatta gtctctcctg atgttattat cggtgctagt
    13621 ttcttgattt tctttacact actaggattc ggattaggtt ttcagagtgt attgctttcc
    13681 catattgctt tcagcattcc aatcgtcgtc ttgatggtct tgccaaaatt gcaggaaatg
    13741 aacgattcaa tggtcgatgc ggctagagac cttggtgcta ataatttcca agtagtcaaa
    13801 aatatcattt tgccttatct ttctccagga atcatagctg gatattttat ggcatttacc
    13861 tattctcttg atgattttgc ggttacattt ttcgtcacag gaaatggctt tacgacgctc
    13921 tcagtagaga tctattctcg tgcaagacaa ggaatcagtt tagaaatcaa tgcgctaagt
    13981 gcgttagttt tcttgttctc catgatattg gtcattggat actactttat tagtaaagaa
    14041 aaccgtccaa aacggctgaa gaaaaacaga agagtacgcg agggggtggc acggctgcga
    14101 tgaaaaaatt acaatctctg tttttaggta ttctcatcat tattgcggtg ctgctgcttg
    14161 gtgttcgtca acttgaaaaa acaagtggca tgagtggagc aaaggtactt accatctata
    14221 actggggaga ttatatcgat cctagtttga tcacgaaatt tgaaaaagaa tatggataca
    14281 aagtgaatta tgaaacattt gattctaatg aagcgatgtt cacaaaaatc cagcaaggtg
    14341 ggacaaacta cgacatcgct ataccaagtg aatatatgat ccaaaaaatg atcaaagaaa
    14401 aactagtact tccattagat cattcgaaga tcaaaggatt aaataatatt gatccacgat
    14461 ttttagactt ggattttgat ccagataatc agtattcgat tccatatttt tggggaactt
    14521 tagggatcgt atataacgat aaattctttg atgcaaatca aattaagcat tgggatgatt
    14581 tgtggaagcc ggaattaaaa gacagtttga tgctgattga cggtgcacga gaagttatgg
    14641 ggctttcttt gaatagttta ggctattctt tgaatagtaa gaatatggca cagctgacag
    14701 aagcagcaaa taaattgaat catttaacac caaatgtcaa agcaatcgtg gcagatgaga
    14761 tcaaaatgta tatgatcaat gaagaagcct ccgtggcagt gacattttct ggcgaagctg
    14821 ccgatatgat gtgggaaaat gaacatttac attatgtgat cccaccagaa ggatccaatc
    14881 tttggtttga taatatcgtt atgccaaaaa ccgtgaaaaa taaagaaggt gcctatgatt
    14941 tcatcaactt tatgctagaa ccggaaaatg cggcacaaaa tgcagagtat attggttatt
    15001 ctacaccaaa tgaagaagca aaagcgttat tgccaaaaga catttcgtcg gacgaacaat
    15061 tctatccatc tgatgacacg atctcccatc ttgaagtcta caaagatcta ggatcgaaat
    15121 acctaggcat ctataatgac ctattcttag aattcaagat gtataggaga taatggcaaa
    15181 actcagtaag aatggggact tatcaacgtt ctaaagagct aaaaatcgtc ctttttctat
    15241 ctgagttttc caatcttcta ccaaaagcgg atgaaacgcc gctttttttg tgttatttta
    15301 ttttttctac cacgtttttc taccagagaa aagtggacaa aaccattgta aaatagggcc
    15361 cgagacgggc tagtaaatct aagattgaaa aagttacaga aggataaagt aattggaaac
    15421 tatgcaaata tacttaaccc ttctgtaatc tattaataaa actaatatat gaatccagtt
    15481 caatatttgt agctatgaaa aaacataaaa atcatattag ataaaaacta aattggtaga
    15541 taaattattt tgtcagatat ctgaggcaaa tattcgacta tttgtgtttc aaagtaaaaa
    15601 ttggaataca aatatagaat agacatattg cagccgatag tttattatgc ttttagacac
    15661 attaaactgg aggaaaaaat gaaaaagagc gctaaagatc gagtttttga tgagctgata
    15721 cgactaacag ggaatatgtc ttctgtcact gccgagaaaa tttcgaagaa tctaggtatc
    15781 tctcgtcaga atgccagcca ttatttgacg agattagtgg aagataaaaa ggtcgagaaa
    15841 ttaccgggaa agcctgtttt gtggaagcct ttagatgaat atgcggttgt agataatacg
    15901 gagcaaataa acgaagcctt tcattctgta gttggtcatg acggaagtct gagagaggtc
    15961 attcaaaaat gtatagccgc tgtcaaatat ccgcctaacg gactcagtgt attaataaat
    16021 ggagccacgg gtgttggaaa aagtttttta gccacaaaaa tttttgaata cgctatccat
    16081 gagcaaatta ttgaaaaaga tgcaccattt gctatcttaa actgtgccga ttatgcggac
    16141 aatcccgaac tgctttcggc aacactgttt ggatacaaga agggggcctt tacgggggct
    16201 gaaaaggata ccgatggttt attggcaacg gccaacaacg gctatctttt tctcgatgag
    16261 gtccatcgcc tatcgaaaga aaatcaagaa aagctctttc tatttattga tactggaaac
    16321 tatcgtccag tcggtgaaaa tgtaaattgg cattctgcta aggttcgttt tattttcgcc
    16381 acgacggaaa aaggtgaaaa ttatttatta gacacctttg atcggcgtat tcaaattagt
    16441 gttatgttgc caacttttga agatcgcccc attcgagaac gattagagct gattcaatta
    16501 ttttttcaaa atgaagcgga tgttttacaa aaagatatta ttgtttcaag agaagccttg
    16561 tctttaatgt tatctcatcc ctttagtggg aatattggta agctgaagaa tatcattaaa
    16621 atcagttgtg cggatgtgta tagtcgaaca caagaagaac cattaacgat tgggaaaaat
    16681 gagatcttga ttcagttaaa tatgctggaa tccgaagtag aaagcttgcc gattgctagt
    16741 ttattgataa agaaaaatca aaagataaaa acggatcgaa tcaaaccgtt tgattatgat
    16801 tcgattttgg aaaaaattac tcagctgata aatgaaggta atttcaatga aaatttttct
    16861 tcgataaaga atgaagtaca gcatttggtg catcacattg ataaggattc ttttttatca
    16921 atgagtagaa aattgatgat tcagatgttt agaaaggtct gggtatccgt tttaggaaaa
    16981 acgtacggat tgacgacgag tggacctgtt gcagaaatta ttagcagatc ctatgtcatt
    17041 tccccaagct ataagacaga cttaaccggg ataaatcgta cattagctgc aaatctacct
    17101 cggacgactt acttatgtaa tcagttcttg gagcatttac caccgctctc agaaaaggac
    17161 gagaactttc taagactgct tattgtcgtg actttatctg attatgtaga tgaatccatc
    17221 gagctgaagg gcctgttgct tgctcacgga gatagtacgg ctagcagcat tcaagcagta
    17281 gtgaatcaat tatgcggcaa ttatgttttt gaagcgttgg atatgccagt agagagtaat
    17341 gtgtcagaga ttgtcgaatc gacaaggaat ttcgtgaaac ggcaagtgaa tacagatagt
    17401 ctagtgctga tcgtagatat gggctcttta aatcaaattt acacacagat caagaacgat
    17461 ttaaaagggg agttacttct tctgaataat ttgacgactt ccattgcact tgatattggc
    17521 ttgaagatga cgatgaatgc gccatttaaa cagattgcgg aggatgcagc agacaagtat
    17581 tcaatcaatg ttcaatactt tgaaggcttt tctcaaagta gcaacattat catttcctgt
    17641 atgtcgggtt tggggatttc ggacaaattg aaagatgttt ttcgtcatca tttatcggat
    17701 gaatccatcg aagttttcac gaaggactac agagaactac gtgaattaat cgaccaaaat
    17761 gatgaaactt attttgacaa gacaaaattg gtcatcacga cttcggatct tccacgttcc
    17821 ttttcaattc ctaatattaa tgtttatgac atcttagacg gtgatggagc agccaatttg
    17881 gagcatattt tgagtcctga aatgaagccg gcagaattta accgcttgat tcaggagcta
    17941 gtaaaattct tttcgttgga aggaattgcg gaccgtttga actttctgaa cccaacgatc
    18001 gtgatgagtg aagtggaaac agtcatttct aaatatgaaa attactatca tttcacttta
    18061 aatggccgtg taaaactaaa tctctatatg catacggcat tgatgatgga acgtttattc
    18121 ttggctcgga cagaaaaatc tgaagaaccg aattatgatt tgaaaccaga tgaagatgaa
    18181 ttttattatg tttctagaag tatttttcaa tcaatggaga tgaaatataa ttttaaagtc
    18241 aatgcttatg agctttcgct gctctatgaa ttattaggac cgtatattca aaaataaagt
    18301 gtctaaaaaa gtgtctaatc tgtttttttt aggttagaca ctttttttaa tgtgaattaa
    18361 cgtgattaaa ccaatgtttt taaaagttgg cacaggaatt gcttatataa aagtgaacag
    18421 aaagaaagga attaaccata tgaagaaaat tctaatagcg actcacggtc acttagcttc
    18481 aggctttctt agcagtattc aattactgac ggggaaggtt caagagatta cggtgattaa
    18541 tgcttatgtg gatgagtgtg attttgaaca ggagttgaat gtatttgtaa accaggtgaa
    18601 cgagcaggat cagatttttg tttttaccga tttatttggc ggaagtgtca atcagaagat
    18661 taccaaaacc tttttggaga aagagattgc tgtaactatt ttgtctggct ttaatctgcc
    18721 aattctgctc gaaatagtat tggcaaccaa ggaattaaca aaggaggata ttcaggaact
    18781 ggtaaataaa tgccaacagg aattaaagat gaccattctt gatgaggtac atgtagtaaa
    18841 tgaagaggaa gatttttttt aggaggaaga aaaatgatta aagcagtgcg aattgatgaa
    18901 cgattaattc atggacaagt agcgatgact tggacaaaga gtctaaattt aaccgggtta
    18961 gtagtagcaa gcgatgaggc ggctaccaac gatattcaaa agatgacatt gaagatggct
    19021 gcaccatcga atgtcaaagt cattattaaa acagttgatg acgcgattca tttgttaaaa
    19081 gatccgcggg cgaaggacat gcgcttgatg gttttagtcc ctaatgtcaa agatgcggta
    19141 aaagttgcga aagctttccc aacggaaatc gaattaatga acgtggggaa tgctgggaaa
    19201 atgacaccgc catcggaaga taagaaaacc ttatcaaagg aagtgatgtt aacgacgtca
    19261 gaaattcaag acttaaaaga attagttgaa ctttatccag ataccgtttt tcagcctaca
    19321 ccggcgatgg aaaaacgttc agctatctct attttgagtg atttttagaa aaaggaagga
    19381 gaaaaattat gtatgatgca tttgtagtcg ctttggccgt ttttattgga gttgctggac
    19441 atgaaatgtt cgggatgtcc atgctgagtc gtccgattgt tgttgctccg ttagcaggag
    19501 cgttgatggg ggatttgcag acggggttga ttgtcggggc gtcactagaa gccatcttta
    19561 tgggtgtcgt caatatcgga atctctagta cggcggagcc ttctttggct gctgggctgg
    19621 ctacagcgtt cgcaatcaaa atgggaggaa acgtggatgc gattattccc attgtctttc
    19681 cactagcagt attaggatta cagttaatga atatgatttt ttcttttgta tgtggaccga
    19741 tggctgctaa atttttcaaa tttgcaaaat ctggtgatca aaaaggaatc atcaatctgc
    19801 acttctttat gtggtttgtc cactatgcgc tttatgctct tattccattc tttgccgttt
    19861 tatttggagc agatgttgtc aaaagcgtct tggataatat tccagaggtc atcatgaacg
    19921 gattaacagt cgctggaaat ctgctgccgg cagttgggat ggcgatgctg ttacggatgc
    19981 tttggagtaa aaatattgct gtgtggtttt tctttggggc cgttgttatg gcgtatctcg
    20041 agttaccatt gattgcaatt gccgcagttg gaacgattat tgcaattgtt atagcccaaa
    20101 gagatctaca actaaaaaat atatctgttc atgcagttca aagcgatgct gctgtaaatg
    20161 caacgcttga ccaagaagag gaggatttct ttcaatgaaa ttagctgatg gaatttctaa
    20221 agatgagaaa aaattggttc ggaagatgtt ttggcgctcg atgactatgt atgcttcggt
    20281 gaatccggtg acgatgggcg gcggtggttt cgcctattct atgatgccct tcattaatca
    20341 tttctacaaa agtgaagaag atcgagctgc ggcgctggaa cgtcatacac agtatttttc
    20401 gacgaccatt ccttgcgcgt cctttgtcat ggggattgcg gcatcgatgg agaaggaaaa
    20461 ttctgaaaaa gctggttttg acgtggaaag tatcaacgcg atcaaaacga gtttgatggg
    20521 accattggct ggaattggcg attcattgtt ctggggagtt tggcgtgtcg ttaccgcggg
    20581 actagcgatc aacttagcca atgccggaaa tattttggca ccaattatct ttttagttat
    20641 gttcaatata cctaattact tgatgcgata ctatggcggc gttttaggct attcattagg
    20701 ctctaaatat attgaaaagc tgtatgcgaa cgggttaatt gaaattctga caaaagctgc
    20761 tagtatcttg ggtctgatca tggtaggtgc aatgacgatc agtatggtca aattcaatac
    20821 cgttttgagc ttttcaatga agggcgaaga actaatgaat gtccaagaaa tcctcgatag
    20881 tatttttaaa ggaattgtac cgttattggt aacattgagc tgtttcaaat tactagataa
    20941 aaaagtcggc gtcatcaaaa ttatttttgg aatggtcgtc ttgggaattt tattgtcatt
    21001 acttggaatc gcatagtagg aagctgcagc tactaggctg cagttttttt agcaaggagg
    21061 gaaaagatga ctattaatga agtaatttat tcacccaaac acccattttt taatgctgag
    21121 ttaaacgacg gaaatgtgac tacttcaaac gaatacagct actatcggaa tattcctgat
    21181 gtaaagggat tgaccttcga tgtaagtaat caaaagacat tagcaaacct tgatgtttgc
    21241 gggacgattc aaacgttgac cttttatcga gaaaatttac taactgagga aaaaccaggt
    21301 gtttgggtca ataaacagct ctctcaaacc aattcgttat ccttaaaggt tgaagtaaac
    21361 gggattgtct accatttgtc agaatcggat catcgtattg aagtcgatgt gattcaagac
    21421 tgtttgccta gatatattca tcattattcg acgtttaagg tcattgtagt atcctttgct
    21481 cccatactgg ctaataagcg tttaagtatg cttgttcaac aggtttacat tgtgaatgaa
    21541 acacacgaaa gccttcaagt ttcagtgaaa gatgtgcctt cgtatcaaga gaagtattcg
    21601 gatcagcaaa atgtgttgat ttctcaaaaa ggaaataagg acacgatcgc acaacaggaa
    21661 gtggcaagct tcgccattgc ttttgtggac ccaaatgctt ttgaagaagt aatgactttt
    21721 caggaatctg atatcgaaaa atggctgaag gaaacattga actattttgc tcagctattt
    21781 gggcagctgt caatgccaaa cgatagagtt gtccatctct atcgtcgtgc actttatcaa
    21841 agcttttcta gtttcggtat gaatcgacag ggacaggtcg tcggcagcaa ttggggcagc
    21901 tatcctgcta ctaatcgaat ttggaataag gatatgtatt acgcatcatt gccattcacc
    21961 atgtttgaac cggagttatg tcaaaaaacg gttctatggt ttgatcaata tggcgttaag
    22021 tttcctggtt caaaatttac aggaggtatc aatcattctc tgagtaattc gttatccagt
    22081 gcgttactgg ctagtcttta ttttgaacat actggggata caaaattctt tgagcggtgt
    22141 ccgcaggttc tactgaatgc ttcaagaatt attgaggaca tattagctca acgtcggtca
    22201 ggggaaccaa tgctttttcc atctgtttgg ttatcagacg cctttgcact tggaaagtat
    22261 cataccggca gcaatctttg tctttggaag gcctgtattg gacttgcaga aatttttgaa
    22321 gccctagaac aactgagtct tagcaagcga tacaaaaaca ttgcctgtaa actaaaggaa
    22381 tcaatttgta aacaaatgac tatcgatggt ccttttggtg agcaattttt ggagggaatc
    22441 ggtgatgagg agaaaacaac ctattcagtg aagcactatc aaaaaccgat tcttgagcaa
    22501 gggttaatct ttttaagtga tgtgattgtg gatggaaaaa ttaatttatt gatgcatgat
    22561 ggagaagaat cagacactac gttgatgcct ttttatcaat ttttagataa taaagatcat
    22621 ttatatcaga acaccatggc cttttctgct agttctttca atccaaccta tagcgaggaa
    22681 atcaaaggca tcacttgggg attagaatcc ggcgccactt ttcctggctt tatcactgtt
    22741 ttaatgagcg agctgcacaa ccctcaagct ttcgtaaccc gattagaaga actaatttgt
    22801 ttggcagatt tagacggttc gtggtggtgg tggccgtatc gcttagaggc tcaacaagga
    22861 gaagtcgtgc gagactttgg ctgcggcaaa tgcggctggg catcgggtct ttttgtcagc
    22921 ctaatgatca gtcaatattt cggattgaaa ttcaaaaaag gagtattgca aattgatcct
    22981 gttgataatt taacgttttc ttggaagaat ttgaagttcg gtcaagcctt catttcgatt
    23041 gaatgtacgc aatccgagtt gagtatttca aatttgtcag aaaagccatt gaaaataagt
    23101 gatacgaaaa aaattcttca cgtagaaaag ggaaaaacga ttcacattca aaggagaaaa
    23161 agatgagtat actaaaaaat attacccaat ttaaaaaaat ccagagtcga gcaatcactc
    23221 ccgaaaatcc aacaggcgag aaaggtaaag ctgcgatgtt gccaagcgag ctaggaccaa
    23281 gccgcaaagg tcgtggcgca attccgctga cttctggtga agaaactgtg attgcggata
    23341 ttactggaac gggaataatt cgtcatatgt ggatgacgat tcgtgatcga acagaatttg
    23401 gcagttttgt tttacgtgat ttaatcttaa gaatttattg ggatgggtcg gatagccctg
    23461 ctgttgaaag tcctttaggg gatttctttt gtaatgggtt tggagagcgt tgcgaggtga
    23521 actcgttgcc gatagtggtt aatcctacag ggggctttaa ttcctatttc gaaatgcctt
    23581 tccaaacatc cgctaaaatt acgatcgaga atttacatcc gaaggatatg tcctcatttt
    23641 tttatacgat aaattacgct ttggtggacg aattggaaga aaatagccta tattttcacg
    23701 caaattggca tcgggaacgc attaccaaat tacaggagga ttataagtta attgatcgat
    23761 taaagggtca aggctattac gtgggtactt accttgcgct tacctgccta gaacgttatt
    23821 ggtggggcga aggcgagttt aaattctaca ttgatgggga tagtgagtat ccgaccgtaa
    23881 cctcaacagg ttcagaagat tattttggcg gggcgtgggc ctttcatgag tacgatgagt
    23941 tcggacgtcc acatgcgaaa aactattcaa cagccttttt agggtatcct taccaatcaa
    24001 atagagatgc cacaagagat cgttttgaaa cgggaaaatt gaatgccgtt catgcctttg
    24061 gtgacgacgc aatgccacga catggtcttt atcgttggca tcttcaagac cccatctgtt
    24121 ttaccgaaga tttatcggtc actttacaac aaatcggcaa cgatgatgtt cgcttatttg
    24181 agcggcaaga cgatgttgct agtgtcgctt actggtattc aacagaagct tcaggaaata
    24241 ctaaacgtca tttcactgat cgagaacgct tgccgcgtta atgaagtgtt tttcacatat
    24301 tcgaagggag gaacctatga tgatatatgg ggcaattgaa gctggaggga ctaaatttgt
    24361 ctgtgcagtc ggtactgagg aattaacgat tttggaaaga gtcagttttc ccacaacaac
    24421 tccagttgaa acaatgaagc aggtcattga tttttttaaa ccttttaagg aacaattggc
    24481 aggcatcggg gtcggctgct ttggtccaat tgatattcaa tgcaaatcaa cgagtttcgg
    24541 tcatatcaca tcaacaccaa aacttgcttg gcaaaatttc aattttgtag gaacgctaaa
    24601 gcaatatttc aatattccga ttgaatggac aacagatgtc aatgcggctt gctatggtga
    24661 atatgttgct ggttctggca aagggttagc aggtgttgca tacttcactg tgggaacagg
    24721 tatcggaggt ggtgccttgt tcaatgggac tttcgtggaa gggttcagtc atccggaaat
    24781 ggggcatatg ttgatcaagc gacatccaaa ggacaatttt tcaggaaact gtcccttcca
    24841 ccaagattgt ttagagggga tggcagcagg accagcgatt gaaaaacggt tgggtgtaaa
    24901 aggccagaat ttattggctg acgattcgtt ttggcagatt gaagcctttt accttgccca
    24961 atgtgcatac aatacaacac tgatgttttc gccagataga attatttttg gcggtggtgt
    25021 aatgaaacaa gaacacatga agaaaaaagt tcaggataaa tttgttgagc ttataaatgg
    25081 atatgttgaa ataccaccaa ttgatagcta cattattacg cccgaattag gtgataatgc
    25141 cggaataatc ggcggattag cattggccag aaaagcggta agaaataagc aaccataatt
    25201 aatgaatgtt tcattgatac tcatgtcaaa agtatttaac cgagtaatca aatgatcaaa
    25261 tgaagttgga taaagcgaaa atgaattcaa ataaaaaggc tctaagtcaa atcgtgttgt
    25321 tttcattaaa tcactgaaag gaaatgcttc tgcgtttcct tttttctttt tgttgtgcgc
    25381 tgtatacctt gaggatattc actggtggcg tacacttaaa tagtaatata ttgtgttact
    25441 ttatgtctgt ggtaatagtt atagttgctt accaatgtat gttcattttt cgaaatgttg
    25501 acttcataat ccttggctta atgtttgaat ttttttggtg atagattttt tcagccgtat
    25561 aaaataaatc gtaattctat tatagagagt tgtgattata aaaagatagc aagaaaaaaa
    25621 aagaaagttt ctatacattt taaatatttt attcctattt ctattgctaa aaaagtagaa
    25681 attctatatt tacctttaac tctcgcttct cttgcaaatg tagttagcat ttt
//
LOCUS       DAFKHN010000035        25566 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFKHN010000035 DAFKHN010000000
VERSION     DAFKHN010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.035"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            237..1877
                     /locus_tag="LY912_001475"
     CDS             237..1877
                     /locus_tag="LY912_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBM6955180.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2031..3353
                     /locus_tag="LY912_001476"
     CDS             2031..3353
                     /locus_tag="LY912_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBM6955181.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIICAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3415..3846)
                     /locus_tag="LY912_001477"
     CDS             complement(3415..3846)
                     /locus_tag="LY912_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955182.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3910..4746)
                     /locus_tag="LY912_001478"
     CDS             complement(3910..4746)
                     /locus_tag="LY912_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBM6955183.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4936..5238)
                     /locus_tag="LY912_001479"
     CDS             complement(4936..5238)
                     /locus_tag="LY912_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBM6955184.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="LY912_001480"
     CDS             complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="LY912_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBM6955185.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5692..5958)
                     /locus_tag="LY912_001481"
     CDS             complement(5692..5958)
                     /locus_tag="LY912_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBM6955186.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6212..6937)
                     /locus_tag="LY912_001482"
     CDS             complement(6212..6937)
                     /locus_tag="LY912_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBM6955187.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7303..7373)
                     /locus_tag="LY912_001483"
     tRNA            complement(7303..7373)
                     /locus_tag="LY912_001483"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7339..7341),aa:Gly,seq:ccc)
     gene            7490..8242
                     /locus_tag="LY912_001484"
     CDS             7490..8242
                     /locus_tag="LY912_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBM6955188.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8258..8737
                     /locus_tag="LY912_001485"
     CDS             8258..8737
                     /locus_tag="LY912_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBM6955189.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8988..10568)
                     /locus_tag="LY912_001486"
     CDS             complement(8988..10568)
                     /locus_tag="LY912_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBM6955190.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10561..11304)
                     /locus_tag="LY912_001487"
     CDS             complement(10561..11304)
                     /locus_tag="LY912_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955191.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11480..12256)
                     /locus_tag="LY912_001488"
     CDS             complement(11480..12256)
                     /locus_tag="LY912_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6955192.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12504..13340)
                     /locus_tag="LY912_001489"
     CDS             complement(12504..13340)
                     /locus_tag="LY912_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBM6955193.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13351..14280)
                     /locus_tag="LY912_001490"
     CDS             complement(13351..14280)
                     /locus_tag="LY912_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBM6955194.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14472..14825
                     /locus_tag="LY912_001491"
     CDS             14472..14825
                     /locus_tag="LY912_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBM6955195.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14899..15555)
                     /locus_tag="LY912_001492"
     CDS             complement(14899..15555)
                     /locus_tag="LY912_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBM6955196.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15781..17715
                     /locus_tag="LY912_001493"
     CDS             15781..17715
                     /locus_tag="LY912_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBM6955197.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17801..19024)
                     /locus_tag="LY912_001494"
     CDS             complement(17801..19024)
                     /locus_tag="LY912_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBM6955198.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19018..20916)
                     /locus_tag="LY912_001495"
     CDS             complement(19018..20916)
                     /locus_tag="LY912_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBM6955199.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(20910..22028)
                     /locus_tag="LY912_001496"
     CDS             complement(20910..22028)
                     /locus_tag="LY912_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBM6955200.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22111..22944)
                     /locus_tag="LY912_001497"
     CDS             complement(22111..22944)
                     /locus_tag="LY912_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6955201.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22937..23854)
                     /locus_tag="LY912_001498"
     CDS             complement(22937..23854)
                     /locus_tag="LY912_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6955202.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24081..25205)
                     /locus_tag="LY912_001499"
     CDS             complement(24081..25205)
                     /locus_tag="LY912_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBM6955203.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25388..>25566
                     /locus_tag="LY912_001500"
     CDS             25388..>25566
                     /locus_tag="LY912_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBM6955204.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSL"
BASE COUNT         7897 a         5093 c         4332 g         8244 t
ORIGIN      
        1 ttctatttat ctatctaaca tatcctttat tcttctactt ttctttcttt agcatataag
       61 agatacgcat agtaatcaag caaggattgt tgatataaaa agaacaaata ccgctatttt
      121 gatttctttt gactctatta ctcatataaa taaaatttat tatacctgct ctttttgact
      181 atatcctcat ctgactccta tacttcgttt gtattaaaac ttaggaggaa tcattcatgc
      241 ttacagggct aaacttatta aataatcctt ttctaaataa aggaacagct tttacaaaag
      301 aagaacgggc aaaatacgga atcactggta tgcttccaag tactgtccaa acattggaac
      361 aacaatctgt ccaagcttac ggtcaatact taagcaaaca gaccgatttg gaaaaacgta
      421 tcttcttaat gaatctattc aatacgaacc ggacattgtt ttataaattg atgggcgaac
      481 atttagttga attcatgcct gtcgtttatg atcctgtcgt tgcggattca atcgaacaat
      541 acaacgaaat tttcttgaaa ccacaagatg ctgtatttct ttcaatcgac gaaccagaaa
      601 atatcaaagc aagtttgaaa aacgcagcag atggacgcga cattcgtttg atcgttgtga
      661 cagatgcaga aggaatctta ggtatgggtg actggggtgt gaacggtgtt gacatcgcta
      721 tcggtaaatt gatggtctac actgccgcgg ctggtatcaa tcctgcacaa gtcttgcctg
      781 tatcaatcga cgctggtact aataacgaag aattattgaa taatccatta tacttaggga
      841 atcgtcatgc tcgtgtagaa ggcgaaactt actacgaatt cattgatcaa ttcgttcaat
      901 cagctactga attattccca gaattgttat tacattggga agattttgga cgaggaaatg
      961 ctgcaacgat cttagaaaaa tacgaagata aaatcactac tttcaatgat gatatccaag
     1021 gcacaggaat cgttgtacta gctggtgtat taggtggatt gaatatatca ggtgagcaat
     1081 tgaaagatca aacgatcttg acatttggtg ctggtactgc tggtgtaggt atcgcaaaca
     1141 tccttttaga tgaaatgatc cgtcaaggtg tacctgaaga agaagcacgc caacatttct
     1201 atcaagtaga taaacagggt ttattgtttg aagatacaaa aggattgact cctggtcaaa
     1261 tcccattcgc tcgtaaacgc tcagaattca ctaatgctga tgaattgaca aacttagaag
     1321 cagttgtaaa agcaatccat ccaacgatca tgatcggtac ttctacccaa cctggagcat
     1381 tcactgaaga aatcgtgaaa gaaatggcgg ctcatacccc acgtccaatc atcatgcctt
     1441 tgtctaatcc aacaaaattg gcagaagcaa aagcaaaaga tttgattgaa tggacggacg
     1501 gaaaagcttt agttggaaca ggtatccctg ctgctgatgt ggaatataac ggtgtaactt
     1561 accaaatcgg tcaagcaaat aatgcgttga tgtacccagg tttagggctt ggtttgattg
     1621 cttcaacagc tacacgagta aatgctgaaa tcatttctca agctagtcga gcattaggcg
     1681 gaatcgttga tgtaacaaaa ccaggagcag ctatcttgcc tccagtagca aaaatcactg
     1741 aattctctca aacgattgct gaaactgtcg caaaatcagt tgttgcacaa aaattgaatc
     1801 gtgaagaaat cacggatatc aaagaagctg ttgaatctgc taaatgggtt cctgaatata
     1861 aatctttaga agattaagat tgttatagta aaagaacata cagaaacttt gtatgacgtc
     1921 taaaaagaaa aaagcgactg cggcaaaaca gcagccagcc aactactgct cttttgccgc
     1981 ttctctttgg cttttttcat acgatacaga ataagaaagg atctgtaaaa atggcacaaa
     2041 aaacaacaac cgcaactgca gttgaggaaa agaaaaaaga agggttttgg tcaacaaaaa
     2101 ttaccggcgt aagtttgccc ctttatttga tcatggtcct tgtcctgatc attgcaatgg
     2161 ctttaggaaa attaccgacg aatatgattg gcccaatcgc tgttttggtc attttcggta
     2221 atttatttca ttttatcgga acaaaaatcc ctatagtcaa aagttattta ggtggtggct
     2281 ccgtttttgc gatctttgcc tctgccgcga ttgctacatt tgggatctta cctgagtatg
     2341 tagtaaaatc cacagaaaac tttgtcagca atatgggctt tttagacttt tatattgctg
     2401 ccttgattac tggtagcatc cttggtatga accgtaatct attgatgaaa gcttctgttc
     2461 gttttattcc cgttgcactt atttcaatgg tcgtctcctt ttttgccgta ggactcgtag
     2521 gtatgcttat cggaaatggt tttgcaaatt ccgttttata tatctcattg cccgcaatgg
     2581 ctggtggtgt tggagccgga gctgtacctt tatcaacgat ttatgcaaat gttttaggta
     2641 cggacgcttc ttctatcatt tcccgcctga ttcctgcgac agcaatgaca aatgtcctag
     2701 ctatcatttg tgcagcgtta gttgctcgtg cgggacaatc aatgccaaaa ttcaacggta
     2761 atggtaaatt aatggaaaaa ggcgaccttg gcgatggaaa acctagaaat gtaaaacctt
     2821 ccattccaca attaggtgtc ggtttgatgg tatcattgac tttcttcatc ttaggacaaa
     2881 tctgtaacta ttttgttcct aaagtccatg cttacgcatt catgatcatt atcgttgtta
     2941 tctgtaaaat cgcaaaccta ttaccagaat attacgaaga tgcagctatc atgttcaaca
     3001 acttgattgt caaaaacttg acagcagctg ttcttgccgg tatcggtatt gcgttattga
     3061 atctaaatgt attggcttct gctttgacat ggcaatttgt tgtcttatgt ttgacaagtg
     3121 ttatcgcgat ttcagtagtt tcaggatttg tcggtcgttt gtttggttta tatccaatcg
     3181 aatcaactat tactgctggc ttatgcaaca actcgatggg tggtacagga aatgtagctg
     3241 tcttatctgc agctaatcgg atggaactta ttgcttttgc tcaaatgggc aatcggcttg
     3301 gtggtgccat cgttttgatc atctcaggtt tcttgatgca attactttct tagtcaaaaa
     3361 aaatacctga tcatcaagta tcggcttgat gaccaggtat tttttgataa aaatttacag
     3421 gattttcaaa aatctttttt gcattttatc ggaatgataa ccgatgcgtt cataaaatcg
     3481 gtgtgcttct actctgtatt ctgcagaatt aagtcttatt gctgatattc ctcgtctttt
     3541 cgcttcttct acgccagtca tcaaggcctt tccgattcct cttttttcag catgtttaga
     3601 cacagcaagt gccataatat tgaacatcgg atcgctgaaa atcgattcat aggactccgc
     3661 ttgtacatag ccagctgctt ttttagaagt aggatcttca tagaccaaga aaaaattttt
     3721 ttctggctcc ttcaacagtt tcttcatttg tctcaccgta acggttaatg gtacatcata
     3781 tcctaattgt tccgcattga tttctcgtag tgcttctgca tctcctaaac gcatttcccg
     3841 caacatccaa atcaccagcc aatttttatt tttttaaatg aattttttta tcacagtata
     3901 ctcctttttt cacttaaaaa aagacttttc agtgattttg acttgcttga atccagatcc
     3961 ttctaatgtt tgcaagatga cgaaagcatt gtaaagattg atcaaaagaa ccacgatgac
     4021 aatcgcttga aaaataaagg tcactttttt tggagacaaa accctgctaa atcttgctcc
     4081 ccacaaacct ccaataacag cagcggggat aacataaaac aacatagata aatcaaagcg
     4141 cataaagcta cttgttaaag caatcgttac caattttgcc agttgagaaa agaaaatcgt
     4201 agatagagaa tatagtgttg cttcttttat tggcaatgca aacatcagca tcaacaaaga
     4261 aacattgact ggtccaccac caatacctaa aaaactagct aaaaagccca gaaccccccc
     4321 acatataagg taccaagtcc atgacgtcaa atgaaatttt ggctgatgat gcttggtgta
     4381 gaagaacgca aaaaccaagg tcaataccgt caaaaaaatt tggatcagct gcacatgctt
     4441 ctcgttttca aataactgta aaaaaacttc gaatacaatg ttgccgacta ctcctccaac
     4501 aacagctcca ctagataccc aaccgacaat ctgccaattc agtgatttcc cgcttgatac
     4561 ttgtcgcaca gtcgaaacaa tggacatcgt gaataccgca actgttgagt aaaaagaaat
     4621 ccctgcaaca gaatgggcgc cgataagatc aagaatcggt ttgatcaaca cgcctccacc
     4681 catcccggaa atagcgccaa ctgtgttcgc cagaacgatc accacaaaat aaatcagacc
     4741 aatcatcttg tatttccttt ctcttgttta tatcttttag cgattgttac tcttttcttt
     4801 tattatacag taaaagaaac aaacgaggct tcgaaagctt ttctactttt taaggaaatt
     4861 tagtgctaaa cgaaaaaacc gggctctact tttcagagag tccagctttt cttacacctt
     4921 atcgattctt ttgttctatt cttcttccgc catgaatgta ttgaatactt cttcgatcat
     4981 atcccattct gcgtctgttt cgatttgttc taactcgcct tctgttccat cttcgttttc
     5041 gatgtatgca taagcttgta attctacatc ttcatcttct gaaacaccag ctggatataa
     5101 aagaacatag ttacgtccaa attcttcttg tccgtcaact gttagcaaga tttcgtataa
     5161 tgtttcattt ccttggtcat ccaccaatgt gatgtgttcg tgtccttcgt gttcgtggga
     5221 atggttatgt tctgtcataa gattacctct tttcttttta ttattaaaat aattgcttac
     5281 ctgagccgtc taaataattt tgtaaaatca tcacagctgc taatttatcg atgacttttt
     5341 ttcgtttcgc tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg
     5401 ttagtcgttc atcttgataa tcaaccggca aggagaatag ttctttgatc ttctctccat
     5461 atgacatgga agcttctgcc cttggtccga tggaattgtt catattctta ggtaatccaa
     5521 ctacaaaacg gtctacttcg tactgcgcca ctaattcctt caaccgatca aaaccaaact
     5581 cttcttctgc ctcattgatt cgaatgattt ctactccttg agctgtccag ccaaagggat
     5641 cgctcacagc aacgcctact gtcttagaac cgacatccaa gcccattact ctcataaatt
     5701 cactccatga tttgagaggt agtctttgac aattacttcc atgatttcat cgcgttcgtg
     5761 acggcgaatc aaatttcgtg catcacgata acgaggaatg taggccgggt ctccagaaag
     5821 caagtagccg acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac
     5881 aatcgctaat gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt
     5941 ttcatctgta aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt
     6001 ctacaccctt attttactcg aagaaaggga aaactacaaa caaatattcc aaacttctga
     6061 ataaattaag aaacacgatt tgtctgattt ttcctttttt ctgtggcttt ttcaaaagcc
     6121 ctctttccat aaagtatacg ctatatttct ttgaaagtat gtttttacac aattttttca
     6181 taaagttcat aaaaaattcg aattgctgct actaattttt cgttttcgtt gcttgccctg
     6241 tctcataatt gatggtgtag ccatcttgaa cattgtagat aaagacattg aattcaattt
     6301 ttttgtcttc aatgctttct gcttccaact gcacacctct tgctaccagt tcatttccct
     6361 cgaaatgagg agtgacacga tagcgtacat gatgatttgt ttccttgata tatgccgcaa
     6421 tatcattttc gtgggcaagc atgtacggag cattcaacga acgtgtccct gtcattaagt
     6481 ttttaatgtt attattttga ccagtcaact ggaaaccaat caaatggctg cggttgtata
     6541 accattgtcc gtcacttaat ttcttttgtt tccaacctgt cggatcaata tacaaaggtt
     6601 ctctcttttc agtaggaaac aagtcttttc ccaacatcgc attggcttgt cctactctgt
     6661 tcaatttgtc tatatttgaa tagctttccc atgtcccttt ggaaagacta agatcctctt
     6721 ttgtaaactc cggctgattc ccattgattt ctatttcttg atgttttcca tcatattctg
     6781 gcacatccgc tacttgagaa gcttgcggtg tggaatcaaa aatggttgta atttgttgga
     6841 agatatctga atctttttgt gtggtggaaa taccgagtgc ccctgcaatc acagcagcga
     6901 cgatccccac gatcgccttg gttgtttttt tgctcatttc tttactcctt tactaacagt
     6961 tccctaaatc ttaacatatg ttcccctata aataaatact ggaaagaaat agaaacagta
     7021 aaaaaataaa accagttttt agacggctta agaatacaaa aaaagagacg gattcatcgt
     7081 ctctactcaa tcacaaaaca ctatttacaa ggtatttatt atcattcaaa aaatttttct
     7141 taatactcaa aactaaacgg cttctgtacg acctcttggt aaacagtgtt caaaagcttg
     7201 catctgcggt aataagtcca accaagtcaa aaacataaga agcttttttg cttgactatt
     7261 cttattactt gatgcagggc agctttttca cagcctcttt taagcgggtg acgggaatcg
     7321 aacccgcgac atcagcttgg gaagctggga ttttaccact aaactacacc cgcgatacaa
     7381 aaacagtata cgcctctttc actccttcct caagtttttt tattctttac gcttccgata
     7441 tgttttgtag taaaataaaa ctaatcaatc aattattgga gaagatgcta tgacgggaaa
     7501 agaattagat ctgttgctgg acacttgttt actcgctggg aaaatcatga tggaaagcaa
     7561 tgcggagatg tatcgggtag aagatacgat gagtcgaatt gctttagctt ctggaaattt
     7621 ccgtttggtc agctatgtca ctcaaaccgg tctctttatt ggtcttgatc gtacctcgac
     7681 catccgaatg gaacaaatta ccaaccgttc gattaattta gaaaaagtag taaaagtaaa
     7741 tgatctttca cgtaaatatg ttgcttcaga gctaacatta gaagaacttt actgcgaact
     7801 gcaagcaatc gaccgagacc gttctttctt tcctgtctgg ttgcaaatcg ttagcgcggc
     7861 agtgatcagt ggaacaatta tggtgttatt tggcggaaag atgaccgatt tacctgtgac
     7921 tttagtcatt ggaggattgg gatacgcagc ttatctatat agtttgaaat tttttagaat
     7981 caaattttta tcggaatttt tatcttcttt attgattggc atagccgcta tctacagcgt
     8041 acgttttggc ttaggaagca atcaggatct aatcattatc ggatgtgtga tgcctttagt
     8101 tcctggagtt caaattacga acgctatccg tgatttgcta gctggacatt atgtctcagg
     8161 agtttctcgc ggaacagaag cgatgatgac tgctacgatg atcggttttg cgattgcttt
     8221 tattttccag cttttttatt aggaaaggaa cacaagtatg gggacgatat ttattcagtt
     8281 ttcttttagt tttttagcga ctgcggcatt tgccgttatt acaaatgtac ctaggcgttc
     8341 attgatttgt tgtggtcttt ctggtgcttt tggctggatg atctactgga tctgtgttca
     8401 aataggcgga tctgctgctt ttggttcatt gcttggttct ttaggagtag cattcatcag
     8461 cgatcttttc tctaaacgtt tgaaaatgcc cgtaacgatt ttcaatattc ccgggatggt
     8521 tcctctagtc cctggtggtt tagcttatca agcggttcga aatctcgtta ctgaatccta
     8581 tcgagaagcg gctcattatg cggtccaagc aattatgatt gctggagcaa tcgctttagg
     8641 tcttgtatta tcagaagtct ttaaccataa catccgtaat ttcaaagtaa agcgtgacgc
     8701 aatcatgatg aaacgaaaaa aacggctttt taaataaacg aagtgtaaca aagaaaaggt
     8761 tgtgaaagag acgttcagcc ttgagcgatg acaaaatatc tcacaaacat tgcgacaagt
     8821 aaccgcagga gcaataagaa gtaattatga gtattaaaaa aagttttgta aaaatagctt
     8881 ctcacatttt tacataaaat tgacttaata ctgagaaact gacttttgaa caccctctat
     8941 ctgtaaaaaa ggggctgcga catgattttt gtcacggccc ctcttcttta ttcaaatttt
     9001 ttccaaaacg ttcgttgata ataaacgatc catagagcgg aaagtattag aactaaaccg
     9061 atcacaggaa tattcactaa ccaaaatgga taaaacaaag ccaacattcc gtataagacg
     9121 ataagaataa tactgatgat caatgaaccc atcatagttg cgactaaacc caaacttcct
     9181 gaacctctgt taaataattg gttaatattg gtccagttca gcagcagcaa ccgataatct
     9241 ctagcgaaat aacgtagtga caataagtag cagccgaata aagaaccaaa tagcaagcta
     9301 gggataaaaa acaaaggcag ctgaaaagac agtccgctta ataatgcgat cccaccagtt
     9361 aaaaaactct gcaatatcca tccgaatctg aacttttctt ttaaatattg gttcatagag
     9421 attggcaaag aacggataaa cagaaaattt tcttgatcca aagaaataag attgctgata
     9481 aaagaagtct gattaactgt taagaaagcc aatgcgatcc ctaccaggaa aacaacaccg
     9541 attaacttat tatctaaatc agttaatttt atttcgcctc ctagggcaaa agcaagaata
     9601 aaaatgattg gagttaacaa ggaagaagaa agaacttgca taatcaaatt aggttctttt
     9661 actaattgag cattgtaact aaataaaagc tgatgcacat tttggttctt tttatgggtt
     9721 ctttttattt tgaactcact gtttgaatca gtcagttgct ctgtaagctt tggtactatc
     9781 agctgtttta cagcaaggaa aaatcccaga gccgtgatag ctagtattcc ccaacccaat
     9841 aaaccttgtt gagaaagtgg ctgactggca gcatcataga atggcaataa tatcgaaatc
     9901 ggatgccgat ctgttaactc attttcaata gtccccgttt gatgattcat ccacatgatt
     9961 ccagcaaatg cgatcagcat cgagctgcca agcaagatac tagaaactgt ttttctatgt
    10021 tttttaaaca ctgctgttcg agccaaacca aaaacaatca aactagccag acaaaaaaga
    10081 ataatcaaaa atagagaaaa caaaaggatt gagataatga tagtaagcaa aatccctaga
    10141 tcagctcgcc atccggttaa aataaacatg actagaagcg gaaaaacaaa aggaatgatg
    10201 gtcaaagcaa ctaccaaaat ctttgctgaa aaaacctgtt cttgtccaaa aggcagaggc
    10261 aaaaatactt gcaggtcatt tccttcaaaa aagatattat aaatgactga tatactttga
    10321 gttaaaccta acataccaaa aagtgccacg taataagtaa agaaacctgg caatttaaca
    10381 aagttcatag caaacatagc aaatccgtaa atcagtaaaa aaatcagccc tgaaaaaaga
    10441 ttttgagaca aaagatagat agttaatcgc tttccctttt ttcctttctc tcttgcttta
    10501 ttcgtgagct gtggattaac atataaaaga ttaactcgaa ttaattctaa taattgtcgc
    10561 ttatacatac ggtccatctc ctgtcgcttg ccttccagcc attttcaaat aaatcttttc
    10621 tagcgtttca tcaggtgagc cattcaataa ttcactaact gccccctgat aaatcaattc
    10681 acctttcttc aaaatagcca gtttatcgca taactgttgt gcggtatcca atacatgtgt
    10741 agaaaaaatg actgtttttc cttttgcggc atgagccttc atcatttctt tcaaatcaaa
    10801 tgctgcttga ggatcaagtc cttgcaaagg ttcatccaat acccaaatat ctggatctgg
    10861 cagcaacgtg ccgatcaaaa tcgttttttg acgcattcca tgtgaaaaac ttgcgattgt
    10921 ttcattttga tgactataca tatcaaaaag cgctgtcaat tctgctaaac gcttttcttt
    10981 tttttgtgtg tctaattcat aggcagctga aatcaagtcc caatattctc cagccgtcaa
    11041 ttgtaaaaaa atatctgggg aatcaggcac ataaccgatt ttttgtttga tactcaatcg
    11101 attttccgtc aatttcattc catctactaa aatcgttccc gatgatggtt caataatact
    11161 aactaaactt ttaatcgtag ttgattttcc ggcaccatta tgtcctaaaa atccaaaaat
    11221 ttccccttgt cttatcgaga gagacaagtc ttttaatgct tgttttttcc cgtaactttt
    11281 acttacattg atgaattcaa tcatttctgt actccttttg tttgttatta ctttttattg
    11341 tacccttcgt tattggtgga gtaaatgtca aaaagagtgc ataacaaaaa aggatagaaa
    11401 cgactaggct gctacttggg ttgttctctt ctacaggaaa acactcttct aacaggtaag
    11461 atatgagtct ttgttttctt taaaatgatt cattttctat cttttcttgc ataaaattct
    11521 ttagtttatc aatacttctc tttcccatct ctagttgttc tccatttgca aatgttacta
    11581 tttcgtttac tctgctaata gatgtaatgt tttcagtatt aatgatataa gcttttaaat
    11641 ctttacataa atactcatat tcgagtgatt ttttatattt tttaattgtg ccgtttacga
    11701 gaatctcttc atctttcaat actaggccta ttttattttt ataacctggc atgctcatta
    11761 gataaaggat ttcatcgtaa tggatatagt gatcgctatt accataacgg acagttgtcc
    11821 accttttttt cgtagcatgt tgaacaggat agttttcttt ttctttcaat aagtaacttt
    11881 ggatgctttt tttatttttt tcataagtga attcttttat caaataacca ctaggcgtaa
    11941 tctttcgatt aataacagtt attgctttat tcggatgaga cgttagataa acaattttac
    12001 acttttcatt cttttctcta agcatttcgc ctagttcgat accgctataa taggcgttca
    12061 aatcgatgtc taggaaaaaa atatctgagg aatagatttc attattttta atgaattcaa
    12121 caaattgtat aacgttcaat ccctgaacga tctcaaattt ccaaggactt aataaaattc
    12181 tggattcttc caaaatttct actagcattt tttcaaaaac caaactatca tccaaaataa
    12241 atatacgcgt taccataaaa agtacctcca ctcgatattt tactatcaaa atcatttcat
    12301 acaacttttc aacatacatg ttaggaataa attgtaattc tcttcacaat cttttccaac
    12361 acctttgaaa ccgatatcaa atactttcag gatgctgctt ctaaaataaa tatcaaacaa
    12421 atgaatacat catgcaaaaa aagccagaca accgacgtcc ttgcgtgtca gctgtctgag
    12481 ctatgtttat ttattttgtt cttttaaaaa gaacgataca catactgatt tttcggagca
    12541 gagactttct cagcgtttgt aacaactaca gatgggattt cacgcttgaa tggttgataa
    12601 tagtctgatt ggatggttcc ttctatttta taccattcat catttttaac cgttactcct
    12661 tccggcatat gcgtcaacaa accaaagact cctgaatctg ccacacaatg gataatgccg
    12721 aatcggaaca agaagatatc tgtattgcta tcgttcggtg tttggtaaac aaatccttca
    12781 tagctgattt ttttgccaat gaattcgcta gggtaattat aaattagctc cataacttct
    12841 aaatagtttt catctgtgat cttgatagtt tgcttatccc catacttttc tttcaactca
    12901 ttcatttggt ctaagtagtc tgatttgttg aaataaatac tggtatccgg ctttaagtat
    12961 tgtgtctgca tctccggatc ccctactgat tctttactta ctgggaaatt aaatcctttg
    13021 gcttctacga tcgtagtgtc gagactaact gttggaaaca acgtccccac gattactggc
    13081 aaagctagca gtacataagc gattccacgt tgataaggtt ttgacaaccc atggtcatga
    13141 tcgtgctcgt gtgccttttc ttctgctttt ccgtttttga cccacaaata cagctgaact
    13201 aaagccaaaa gagcagataa aatcattgaa agaatagcta agtagcgata atggacattg
    13261 atatattgat cgagtttgcc agaaacttgc aagtacatca tcaattcgaa atacccagat
    13321 aaaatcaaaa accgcagcat attttccctc ctaaataaat aatgtgaatc caataacgct
    13381 aagggcaatc agtccgatca gcgataaaat aaagcgtcct gtaaaatatc gtttcatcat
    13441 cagtagattt ttgatatcga ccattgggcc aaagaccaaa aaggcagcta caggtgctgt
    13501 gccgaacaga cttaacaaag aagatcctat aaacgcatct gcttctgagc aaagagacat
    13561 cgtaaaggcc aataacagca tgatgataat ggctaaaatc tttgttgagc cgagcgttag
    13621 cataattcta gttggtaaat aagtctgcat cgcagctgcg attaatccgc caatgatcaa
    13681 ataacgacct gtatcaaaaa attcgtcgat tgaatgtgtc aacacatgcc cagtttgatg
    13741 gatcagctga ttttttggtt cattcttctc actttgttct tcttcatgga catgatgatg
    13801 gtgattttct gctactttag acgtgatttt ttctttcaat acagcgtctt tttgaaaata
    13861 ggcaagccag acaccaatca caagggcaac aaaaaagctg cctatcaccc gccagcttgc
    13921 catctgccaa gaattgccaa atgcgataaa agtggaaaaa atcacgattg gattgatgat
    13981 cggagcagtc agcataaaag caaacgctgt gtgaactggt acgccttttt taacaaattg
    14041 atgaacgatc ggtacgatgc cgcattcaca tgaaggaaag aaaaatccta agatcgaacc
    14101 agtaaaaata gagaagatac gattttcagg aagccatctc ttcacacgtt ctggggtcaa
    14161 aaatacttgt aaggcgcctg agataagaca gcctaataat acgaaaggta atgcttcaat
    14221 aacgatcgat aagaaaatcg tactcatctg caaaaccgaa tttggaataa aagaaaacat
    14281 gagtttcctc ctttttattt ctagttcatt cgctttgcaa atatacgctt ttattcaaaa
    14341 aaaacaagtt gctctgtaaa tttttacaca actcttattt tttaccaaag cacttcaatt
    14401 gactttttct gttattccca ttaaattaag gtctcataca tatcacttct atcataaaag
    14461 ggagaataaa aatgaaacaa accactaact tgactgaagt tcaagacata ctgcaacagt
    14521 catccgttgc cgtcatttat ctttcgatgc ctaattgcag tgtttgtcac gctgttcgtc
    14581 cacgactaga ggaacttctc acacattatg atattccggc acttcatttg gatgcatttg
    14641 aaacaccaga agtagctagt aaatttgaag tgctgactgc gccagttgtc ctgatttttc
    14701 atcaaggaaa agaagtcttt cggcaagcac ggttcatcga ctttaaaaaa atccgttatc
    14761 tactagatga actgacagca gaagatgatt ccctttctta tgaagaaatc ttccgaacaa
    14821 aataatcgtt gtccaaacag aaaaaagcga ttgaacaagt gaaagttttg ccttcatttg
    14881 ttcaatcgct ttttattttt attctgctgt attttcggaa tgcgcatttg cgtcagaatg
    14941 caagaaatag atcaaggttt gcaattcatt cgtcaaatca acattttgga tcaatacatc
    15001 tgacggagca ttcaatcgag cagcggtaaa gttcaagatt cctttgattc ctgcttccgt
    15061 taactgattg actacttctt gtgctctttc agcgggtatc gttaaaattg ctacttcgat
    15121 ttgttggatc ttgatttgtt ctgacatatc ttccattgga taaacgggga taccgtctac
    15181 gatgcgccca acgatttcct cattcacatc aaaagcacaa ctgatacgta tgctattact
    15241 ttgatggaat ttgtatttta gtaaagcact tcccaagttc cctacaccga tcagcgcaac
    15301 atttgtcaat tgatcgtcgt ttaatgtctt tgcaaaaaag tgcataagat cttctacatc
    15361 ataaccatac ccacgttttc ctaattcgcc aaaataagaa aaatctcgac ggatcgttgc
    15421 actatctact tgaacggctt cacttaattc agttgaagac acttttttct ttccagcatt
    15481 atttaaaatc cttaaatagc gataatacaa aggcagtctt ttagctgtcg cctttggaat
    15541 aatatgatct ttcacgaaat gacctccacg tattgtctaa ttacatcttt gatttctcca
    15601 tcatagcagt atttatagga aaaaatcaat tccattgctc agatattgtg aaattttatt
    15661 ctttattcat ttatttatca tttctgcaaa tctcgcagta taatggaatt tatggtagac
    15721 tactaattga aaaatagttt tttatttgag gagaattcac aaagtagaaa agaggattcc
    15781 atgatattat tacaagccaa tcagattgct cgccattttg gtgcagaagt cttatttgaa
    15841 aacatacatt tagaaatcag tacaggcgct cgtgtcgctt tagttggcag aaatggcgct
    15901 ggaaaatcga ctttattaaa gatcattgct ggaattgaag cacctgatga aggaaagatc
    15961 gctaaaaata aaacagcgac tctcggatac ctcgctcagg acacaggact tgattccaat
    16021 gaaacagttt ggaacgagat gctgaaagct tttgaacaag ttagacaaat ggaagagcgg
    16081 atgcgcgagc tagagatttt cattagcgaa ggtacgccag acacacctgc ttatagttct
    16141 tatttaaaag aatacgaccg gctgcaacac gatttttcag atcgaaacgg ctatggttat
    16201 gaaaatgaaa ttcgttccgt attgcatggg tttaaattcg attcttcatt ttatgatcag
    16261 aaaatcgata ctttatcagg cggacagcgc acacgtttag ctttagctcg catgcttttg
    16321 caacaccctg acattttgat tctagacgaa ccaacgaacc atttagatat cgagacactt
    16381 tcctggcttg agaattatct gcaaagctat actggtgcat tattgattgt ttcccatgac
    16441 cgttattttt tagataaagt agtcaatgaa gtctatgaat taagcagaag aaaaatgcgc
    16501 cattacaaag gtaactattc gaaatatcta gatttgaaag cagaacagtt agcaagtgaa
    16561 tggaaggctt atgaaaagca gcaaacagaa atccataaat tagaagactt cgttgctcgg
    16621 aaccttgttc gcgcctctac cacaaaacga gcgcaaagcc gcagaaagac attagaaaaa
    16681 atggaccggc tggatcgtcc tcaaggggat gaaaaacaag caaactttct attcagtata
    16741 gaaaagcctt ctggaaatgt agtcttgcaa atcgaagatg ccgctatcgg atatgataat
    16801 gtcaccttat ctgaaccaat caatctagat atccgtcgtc aagaagcgat tgctctagta
    16861 ggtccgaatg gtatcgggaa atcgacgttg ctgaaatcaa tcattcacca gatccctttt
    16921 atccgtggaa aagaaacgct agggacaaat gtcaccatcg gctattacga tcaaggtcaa
    16981 gctgatctgc atacaaacaa gacgatccta gcagaattgt gggatgagca tcctaccact
    17041 ccagaaaaag agatccgaag tgctttaggt gctttcttat tttctggcga agatgtagaa
    17101 aaaccaatcc ctctgctaag tggcggtgaa aaagcacggg ttgctttagc caagttagcg
    17161 atgaacaaag aaaatttttt gattttggat gaaccaacaa accatttaga tattgacaac
    17221 aaagaagtat tagaaaatgc attgatcgat tatgacggca cactgctttt tgtttcccat
    17281 gaccgatatt tcatcaatcg gatcgcgaca aaagtcgtcg aactctctga aaatggcagc
    17341 aaagtctatc taggagacta tgattattat ttagagaaaa agcaggaaga agaagaaatc
    17401 gccgaattgt tggcacaaga tgagccagaa tctgctcctg ctcccacgaa caaatctgat
    17461 tattaccaaa gcaaagaaca gcaaaagctt atccgtagcc ttcaacgaaa aattactcag
    17521 gttgaagaag aaatggcgcg gatcgatgaa tggatcgatc agttggaaca agaaatggtc
    17581 gcgccagaaa acctggaaga tcacgtaaaa ctcaatgagc tgaaccaaga tttagaagct
    17641 gctagacaag atcaagaaac aaaattgacg gaatgggaag aactaagctt ggaattagaa
    17701 gaatatgaaa attaacgaaa aaaccaaaac agaaaccatt catgctgttt tggtttttct
    17761 ttttttattt tatcaaacaa aaattccata tttacctttt tcaccaataa gaagaccaat
    17821 tactagtcat tctcactaaa gcttctaaat aatagtaatc accccaaata caaggtgtat
    17881 ttaccccatt atttttgggc ttattataaa cagactgtgt taaaaagcca tcttcttctt
    17941 ccgttgtagc atatctttct ttcaattgtc gcataatttt ccaaacagca gactggtata
    18001 agttcttttc tgttttgtct aatagacctg attctattaa ttctaataat ccacaaacca
    18061 tgatcaccat actagatgta tctttttctt ctctgctaga atcatcaaag atcaaatccc
    18121 aataacaaat ggtatcttct ggcaaccgat tcataaaata attggctaat attttgctta
    18181 aatcaaaata tttttgttct ttcaaataac gataacttaa tgcaaaaccg taaatccccc
    18241 atgcttggcc tctagcccaa caggaattat cactataacc ttgatgcgta cttccatatc
    18301 ttggttttcc atctttgaca tccatataaa atgtatgata agttgaacca tcttctctta
    18361 ctaaataatc tgctgcattt tgaatatgag cctgagcagc ttttttatat ttttgatttc
    18421 cagtttcttc actcgcccaa tacaataatg gaagattcat gcaacaatcc atgatcattc
    18481 taccttgttg tgaaggatca ctaggatctc cccaagcttg tataactcct gccttctccc
    18541 aaaaacgctg aagtaatgtt tctgcagcat caattgaagc ttccttcatt tttcgatttc
    18601 ccgttatttt ataatctgct acggttgata aagaatacaa aaaaccaaga tcgtgatgat
    18661 tagtgataat ttgacagtca atcctgtgga taaaatctat atctgctttt tcagctgttt
    18721 gttgaaataa aggatcaccc gtcttctcaa ataacaacca attaattcct gtccaaaatc
    18781 cttctgtcca accaatattg tctcttaatg gataacgtcc ttttatagga cactcgcttg
    18841 ggaattgata ctgactgtta ctgatacgtt tgattaacct ctccgtgtgt ctgcgacaac
    18901 gctcgatctc attattccat tctttttcca ttaattcttt ataacattca tttatccatt
    18961 tttctggatg tattatctct tcaaacatca ctttatcaag catttcccca ccagccttta
    19021 gcataatttt agtctttttt tattgttttt attttggata gttagcccgg ttgtcccatc
    19081 aaaatcaatt ttgggacgat tgttccatac ttctaaacta taatcccgat cttgatgagc
    19141 aaccactcct gttccgagcc aatgggttcc ttttccaaat gtaccctcta atccaggaat
    19201 aaaagtgttt tcccatgtca tcaagtttgt attgggcaaa cccataatag ctgtggattt
    19261 tcgtttaata gtatcgtcac ttaaacagat aatacctgaa aagccagctt cactcaccct
    19321 atagttttcc ttgtcttctt ctatgattat tccttctttc tcaggagaac attcaatagc
    19381 aaaccctgtc tcatatagaa catattctgt atctaattct actttgtgta cgcgaatctg
    19441 ccagccttca aaaggaataa gccaagttct gatttttgcc tgtaaagtag gttcccatgt
    19501 agaggcaagt acctctttct tacatacaat gtctcgtaca ttatttcgaa cgatgaactg
    19561 tccataggtt ttgatgctct cattcttaaa actggtcgtg atatatgtgt ccgctcgctg
    19621 aatccctagc attgaatcca ttgccatttc tgctttcaat tgattcgctc gcggtatcga
    19681 aaaaccaaat tgactagaat aagcaaattt taaatatttt tcattggtca atgtatggaa
    19741 atttggccct aattgtcccg cattcaaaaa aaatgtatgt ccattatcat gttgtatgag
    19801 caaattggct tctgaaagaa gtttagttcc ttcacgaata ggcataggca tttctttagc
    19861 cgtccaatac tcatggtctt caggtagcgc caacaataaa aaaatcttat tcagccataa
    19921 tggagataac gtactattat agggttcagt caatgtcaat tgagggtagg tataaccaat
    19981 attcaggata cctttttcat caaatatttc tttttgcatc caccatctta tattccgatt
    20041 gactaacccc ttgatttcac ctaatttaaa aggcaaaaga tcggcccaca acatagctga
    20101 ccaaaagctt gaaactgcaa aacgataaat catgcttcga ccaaaaggca catttgcacc
    20161 atcttccgca aaaaaatgaa tatagtctct agaaaaatca atagctcggt tcttatatat
    20221 ctggctaatg ggcttttctg gttctagtac gctataaatc aaaccataat aatgaaatgc
    20281 aaaaggatta taataatctt ggcgacctct tgaactgtct cgataccagc cattttgaag
    20341 ataacaattt tctatattat caaatgcttc tttcagtgct gattctttaa ctggataacc
    20401 aaatttttgg ataattgttc cgacaattat cttaaaaaat tgccaattac catctgcaca
    20461 ttcatattca aaaatttgcg agaaccaatg aataatctgg cttttttctc ctgtatctaa
    20521 ttttttccat aataattgtt catgatgata taacgctaat aacattgcgg gcatttctac
    20581 catacgctgg tctctttcat gtatttctcc ccaataatcg ggatgggaag gatctgttcc
    20641 agcttttatt cctgatagaa ttaatttcaa ccatcgttca tctaattggt caattgcggg
    20701 ccccgctccc cataaaaccc gagagaatcc ttccattcct gcaattttat ttccatatcc
    20761 taccccttga tgtatataat caatttgtgc gccacttgct cgataaaacg gctggagtgg
    20821 ttgatttatc tttttaaata agtcaaagta atcctgtctg gtccttaata gtggtactgg
    20881 atgtttcatt gtattttctc ctctttttac taccaaatag ctaattccga ctgttctaat
    20941 cgaagtaagc cttcaataaa aaaataatca gaatagatca gtggcacatt ataagtcagt
    21001 tctctatggt atgcttctgc tccgcctcca atgatcccat cttcatccat attccaattt
    21061 gcatagtgct tttctgtctt ttggagtata ttgatagcag cttcatgata catttttgat
    21121 cgtacagagg aaacatatcc tgctaattcc agaagaccgc atgcagcgca tactccagca
    21181 ctggtatcaa tattcgaatc ttttacagca aaatcaatga gaggaatata accagttttt
    21241 tcgattttct gaataaaatt tactgctatc ttttctgcta tagctagata gtacggattt
    21301 tttgtgtaac gataacttaa cgcgaatcca tataaagccc atgcatttcc tctgctccaa
    21361 caagaattct cattgtatcc ttgcccgcca agtaaccgaa tatatttccc tgattctgca
    21421 tcaaattctg cgatatgccc ggttgatcca tctttcctca ctagatactt agctgttgta
    21481 tctgcatgct gccgagcaat tttagagaac ctcggatcac cagtttccct cgaagcccaa
    21541 tacagtaatg gtaaattcat catactatca ataatcatcc aaccaggttt atggtcattc
    21601 catgctacta aatagttccc tgaaatatta tagcgtccag caagtaccgt agctgcatgt
    21661 aaccctagtt gtcgactatg tttgttttga gactgttgat aatgtgcaat agccgatggt
    21721 aagaataaaa aacctacatc atgatgaacg tctgaaaaat ggtacagggc agattctaat
    21781 aattgttctt gttgtattgc tgcctctttg aacttttctc gttttgtctt gtgaaagagc
    21841 tgccataaaa taccactcca aaaaccattg gtccaccagt cgattcctct gtcctttatt
    21901 acgtctgtat attttccgtt gtaagaaata tatggaattt tattccccat tctgtctaat
    21961 tccgcatcta tcttttcaga agctacattc aaaatttttc ttgaccattc cttcgtctgt
    22021 tcattcatgg atatcccgcc attcttttaa tttttatgaa tgtggagttg ctcctagaac
    22081 gaactagatg gttaacattc gttatttttt ttacttattt gcagctccaa tgtcattctc
    22141 cttaaattta gactgcgccc acacataaat caagaccatt gggatcactg aagttgctaa
    22201 aattagcata attgcgccat aattaattgg ctcacctgta ctagaaaccg tcatattttt
    22261 gataattaag ggaaccgtat atttatcttt atctgaaagc atgactaatg gaaatagata
    22321 ttgattccaa cttcccataa agataagtaa accactagta ataatcgtag gtgataaaat
    22381 cggtacagcg attttcgtaa aaatcaccca ctcattggca ccatcgattc tggcagcctc
    22441 catcagtgct gtaggaaatt gactgctata ttgtcgcatc ataaacactg aagttgtact
    22501 ggcaatcgaa gggatgatca cacctgcata agtattcgat aatcctaaac gactcataat
    22561 gtaaaataaa ggaatcaatg tggtaaaaaa aggcaccatc ctagatagca taactgtatt
    22621 gaacaacagt ttattcccca taaaacgata ctttgctaat gcataacccg ccattgtaga
    22681 actggctgta gctgaaactg tactgattac agcaataaca atcgaattcc aaataatcaa
    22741 gggataatta tatctcgcca tgatggcttg ccagtttttt aatagcatat ccccaaactt
    22801 gaaattgatt ccgccactta aaatttcttg attactttgc gttgaagcta caatcatata
    22861 taaatatggc atcaaaaata ttaaggcacc aaacacaata atgacgtacg taaaaattct
    22921 gctttgtatc ttttgtttag tcatttttat cacctccgaa tttaaattga atagccgata
    22981 atataacaga tacaaacacc atcgtccagg caatagcaga ggcttttcca aaatcaacca
    23041 tttcaaaact tgttttatat aaattgactc ctacgaccaa agctgaattt tctggtccat
    23101 tggaagtccc aaagaatata tttgggatat tgaaattacc caagccattg atagtggcta
    23161 aaactgtggc cattaaaatg attggcttta gcatggggat cgttaataaa aagaattgcc
    23221 gaaatttcga tgctccatct atttcagcac tttcgtatat ctctttagaa atcccttgaa
    23281 gaccagctaa aaataaaata gtgttatatc ctacactaag ccaaatcatc gtgatgatca
    23341 ttgatattcg tatccaaaaa ggatttgtta accactgtac accgttaatt cctagcgcat
    23401 tcaaaaatcc attgaataac ccagtcggat tgaaaaaagt catgaatacg gaagctacag
    23461 ccaccgttga tgtaatggtt ggaatataat agacagttct aaaaaatcct tttcctttta
    23521 actgtgctga attcaataaa acagcaaagt aaatagctaa tagcatcgtt attggaattg
    23581 atcctgccat gataatcaaa acattcgtgt aagatttaat aaacaatgga tctcggaaga
    23641 tagctagata attgtcaaat ccaacaaatt caaatgagta gccaattttc ataaaactaa
    23701 aagcaaacga gataatgatg ggaatcaaaa tcgtcacaat aaagaaaata acaaaaggtg
    23761 tgaccaatcc ataagcactt tttttatgag acgtatctgt tgcttttttc ttgctgttct
    23821 ttattgtctt gcttggtaac gaagattgca tcatcgttaa gtcctcctaa tattttttaa
    23881 tcaccagtta attttacgcc gtacttatga gcaaaatttt ctgcttcttt tagatatgaa
    23941 ttttcaaaat cacctgtttg ccaatagtta tatgcagcgg tagtcaaata agacgtagca
    24001 tctgaataag tggctggtaa aacagtattt gatgtatttt cattgatttt attcaatagt
    24061 tcatagtatt tttgtcctcc ttagtagtca aactttttct cagctgcttc tgtttgatag
    24121 gccaatgagt tagatgtagc cacgcccagc tccagtgcgt tggctaagca ttcttcatct
    24181 gtcagcataa atgtaagaaa ttgttgtgcc acttgtggat ttttggcatc tttagggaca
    24241 taaaaacttg atcctcctga tactgcacct tttcctggat tttcttttga aaaaggaatc
    24301 agtggagcca tgcgccattt gtcagatgca tcaggaaaat tcaaagacat attcgtagca
    24361 taccagccgc cagcaacaaa cattgcagat tcttgaaatg ctttctcagc atcttgtgca
    24421 ccgtagaaat gtacaatatc tgagtcgatc atttctttga ttaactttgc agcatgtttc
    24481 gcttctttag tattcagacg gatatttcct tcttcatcaa gcaaagattg attctgctgg
    24541 gctagcatgt tgataaacaa ttcttggtcc ccagattctg gcaaggcaat tccaaaacta
    24601 ccagtttttt cttttaatgc ttttgccacc tggatatatt cttcccaaga actgatttct
    24661 tcaaaatcta cacctatttc agcaaatttt tttggttgat aataacaaag tgctggggta
    24721 aaatcactag cccaaggaat aatcgtttca ttactcgttt gttgacgcaa aatattcaat
    24781 ttttgatcat aaaactgatc gccatatttg tcataaaatc catattcatc agcactataa
    24841 aaagcatctt gaaatttttc cagcacacct gctgctgaag tgtctgccat ggagataata
    24901 tccggcatat cttcgtgtgt taccaatttt ggggtgatca tttgtactgt tgctgttccc
    24961 gaagctacat tcacaatttt taagtcaata tttgctccag ttttgcggtt atagattttt
    25021 gcagcatttt caacatagtt tgtcagtttg ccgtttgcga catatacttc taatgtagtg
    25081 gcttttttta tcattggatc tgcgatgttt gctgttactt cttcgttagt ttttccacat
    25141 gcacttaagc tgaataatag ggtaatgttt agcaaagcta tcaccaattt gtatcttttt
    25201 ttcatgtcta tcccttcttt cttttcaagt tcttatataa aacgctttca cttatgtata
    25261 ttaacggaat tagtaacaca aatatttata taaaaaaata ttttacttgt cgttttggct
    25321 tttcattttt gttataatag tcattaatta taaatagaaa gctttttata taaaaagaga
    25381 aaggaaagtg gttcttttgt taacaaacaa ccaatcctcc aatcttgtca aaaaaacact
    25441 aacctattcc atagataccc atcttcattt atctgctgct ccctattttc gactactaat
    25501 aaatgaaagc gctaatttat atgctgaatt tgcacataaa tctatagaac tagataatcc
    25561 ttccct
//
LOCUS       DAFKHN010000036        25405 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFKHN010000036 DAFKHN010000000
VERSION     DAFKHN010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.036"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            37..3564
                     /locus_tag="LY912_001501"
     CDS             37..3564
                     /locus_tag="LY912_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBM6955205.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3561..7283
                     /gene="addA"
                     /locus_tag="LY912_001502"
     CDS             3561..7283
                     /gene="addA"
                     /locus_tag="LY912_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBM6955206.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7352..7693
                     /locus_tag="LY912_001503"
     CDS             7352..7693
                     /locus_tag="LY912_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955207.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8002..9045
                     /gene="pheS"
                     /locus_tag="LY912_001504"
     CDS             8002..9045
                     /gene="pheS"
                     /locus_tag="LY912_001504"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBM6955208.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9050..11470
                     /locus_tag="LY912_001505"
     CDS             9050..11470
                     /locus_tag="LY912_001505"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBM6955209.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11640..12650)
                     /gene="trpS"
                     /locus_tag="LY912_001506"
     CDS             complement(11640..12650)
                     /gene="trpS"
                     /locus_tag="LY912_001506"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBM6955210.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12904..13641
                     /locus_tag="LY912_001507"
     CDS             12904..13641
                     /locus_tag="LY912_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBM6955211.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13655..14470
                     /locus_tag="LY912_001508"
     CDS             13655..14470
                     /locus_tag="LY912_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBM6955212.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14483..15130
                     /locus_tag="LY912_001509"
     CDS             14483..15130
                     /locus_tag="LY912_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBM6955213.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15146..15802
                     /locus_tag="LY912_001510"
     CDS             15146..15802
                     /locus_tag="LY912_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBM6955214.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            15964..16785
                     /gene="racE"
                     /locus_tag="LY912_001511"
     CDS             15964..16785
                     /gene="racE"
                     /locus_tag="LY912_001511"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBM6955215.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16788..18143
                     /gene="rph"
                     /locus_tag="LY912_001512"
     CDS             16788..18143
                     /gene="rph"
                     /locus_tag="LY912_001512"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBM6955216.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18144..18662
                     /locus_tag="LY912_001513"
     CDS             18144..18662
                     /locus_tag="LY912_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBM6955217.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18769..19269
                     /locus_tag="LY912_001514"
     CDS             18769..19269
                     /locus_tag="LY912_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBM6955218.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19549..20469)
                     /locus_tag="LY912_001515"
     CDS             complement(19549..20469)
                     /locus_tag="LY912_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBM6955219.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20634..21647
                     /locus_tag="LY912_001516"
     CDS             20634..21647
                     /locus_tag="LY912_001516"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBM6955220.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21757..22512)
                     /gene="fabI"
                     /locus_tag="LY912_001517"
     CDS             complement(21757..22512)
                     /gene="fabI"
                     /locus_tag="LY912_001517"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBM6955221.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22732..23172
                     /gene="fabZ"
                     /locus_tag="LY912_001518"
     CDS             22732..23172
                     /gene="fabZ"
                     /locus_tag="LY912_001518"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBM6955222.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23287..24048)
                     /locus_tag="LY912_001519"
     CDS             complement(23287..24048)
                     /locus_tag="LY912_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBM6955223.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24237..25331
                     /locus_tag="LY912_001520"
     CDS             24237..25331
                     /locus_tag="LY912_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBM6955224.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8406 a         4417 c         5370 g         7212 t
ORIGIN      
        1 aaggagcacc gtatcatgtg ttgaaggagg aaaagcatgt ctttacaatt tattcttgga
       61 aacgggaaaa aagatcaccg tcaagtcttg atcgacgaag catccgcttg gctcgaccag
      121 gatgcaagta accaagtatt tttccttgtt cccaactaca gcaaattcga acaggaacaa
      181 gaaattttag cggagatgcg aagaagaagc ggaaaaaaaa ctttcagcac aacaaacgtt
      241 caagtattta gtttttatcg tctggcttgg tatttgctgc aacagacaac tcttcttaca
      301 ggaaatgaat tatcagaatc aggatctgca atgatcttgc gacagatttt agaaaaaaat
      361 gaggaagaat taacaatctt tcgcggagaa atcaataaaa gagggtttat tcgtcaatta
      421 caagaactct acagtgaatt gcgtacagga aatattcaac cagaagacct gatgctttta
      481 tttggtgatt cacctaatgc agaagaccag caacttaaaa tgaaagactt gaagctgatt
      541 ttttcagctt atgacagcga attgactcaa cgtgcactaa caaatgaaga tgcactatct
      601 atactagcaa attatatgca gacacaagat ttcaacaacg tcaaatttat tgtcagtggt
      661 ttttctcgaa tcaatggtca agagtatcaa ttactgcagg caatgatgga aaaggggcaa
      721 ttggttgtcg atttattgct ggatcgtcct tatacagcgg atcttccaga agtacttacg
      781 ctctttcatg agactggaaa gctttatttc cgtctttttc aaagtgcaag agaacggaaa
      841 gtccctatat tagtggaccg atttgcacca gagcagactc gtccgacaga gcttcaactg
      901 ctgcaaacaa tgtgggaaga gacatctagc caaaagaaag cggcagtaca caaaataggg
      961 ggacaagagc atctccattt gtgggaagct gaaaatccaa ctgaagaagt ccgacaatta
     1021 gctgttgaaa tcagacgact agtcagtgaa gaaaactacc gttatcgtga tatccaagtg
     1081 ctgacaaaaa atatgtcttt atatggaaat atccttcggc cgatctttca agaaatggca
     1141 attccttttt atatcgatga agaacaaatg atggaaaatc atccgctgat cgaatggatc
     1201 aacagtctgt tcgctcttga ccgctattct tatcggctaa gtgatattat gcgttttttc
     1261 aaaactgaat tatttctgtc gacggaagca gaaaccgaac ttgatgaatg gaaacaagag
     1321 cgagatgaat tcaggaaaaa actggacatc actgaaaatg tagcacttgc ttacaattat
     1381 caaggaactt attggactcg tgaaaaagac tggcagtttg tggcgtatga ttttgaagca
     1441 gaacagattg aagacgtaca gtatttggaa gaacagtcaa atacgattag acgattattt
     1501 cagaaagctg taccagtatt tttgaaaaaa ataaagaaaa gcaaaacagg acaagaggcc
     1561 gcaaatgttt tttatcaatt tttgatccaa agtggcgtac agcaacaatt attgttttgg
     1621 cgtaatcagg aagtagacag aggaaactta gaagcggcaa gaaaccatga gcagacatgg
     1681 ggagcgctga ttgatctgtt ggatgaatat gtagtaattt atggtgaatc ggcttttgac
     1741 tggtcactgt tccaagaaat cattacaagt ggtctagaaa atctaagtta tggtaaaatc
     1801 cctaccgcaa tcgaccaagt gcgaatcaat cgtttggaat tagttcgacc aaatcaagct
     1861 gccgtcactt ttgcattagg gttgaatgat caagtgtttc cagaccgaaa agagacaaaa
     1921 ggattgttgt ccagtgaaga acgagaagta ttaaatcagg ccttgccaga tggacagttt
     1981 ttattcgacc catcaaagga aagtatctct tttgagcctt tccaagccta tcttgttttt
     2041 ctttccggaa cagatcgatt atatcttagt tatgcacaaa gctatgacac agatggttcg
     2101 ctgaagatgt ctccttattt gcgtagaatc acagaatatt tatctgttcc cgtcgagaga
     2161 aaagagcatt tgacgatcga aagcgaccct aattgttatg tagggactta cagaagcgga
     2221 atcaatacag tcaataggat ttatcgatta gctttagatg aaaaaaaacc tgtaccaaag
     2281 cactggcaaa agctcaaaga attagtactg aattcgtcat ggcgaaattt tgctttacag
     2341 atttttgaaa gtcaggaaca tttaaatgtt cctgtttcga tgccagaaaa aatggcggaa
     2401 gagctttatg gaaaagagat ttatacttca atttcacgta tggagaattt ttataattgt
     2461 gaatacaaat acttcatgca atttggtttg aaattgaaag aacgaactgt ttatggtcta
     2521 actccagcag caactggtga tttttatcat gaatcattgg atcgtttctt caagctactg
     2581 ttttcaaacc aattatcctt agtgaatatg tccgatgcgc agcgtagaga ctttactgaa
     2641 aaagtgctgc aggaagtatt cggagaactt cggtttgaga tattggatag ttctgcaaga
     2701 atgaactata tccgctacca gttaggacag acgattcaaa aagtgacatg ggctttgcaa
     2761 aaacagagca aaaatacagg catgcatcct cttcagacag agattctatt tggtcagatt
     2821 gctggagcaa aaggtatcac aggtctggaa ttaccgttga gtaatggtgg aaaactccat
     2881 gttcgaggga aaatcgatcg aatcgatgta gcttctgaac aagaagatac ttggctaagc
     2941 gtcgttgatt acaaatctag cggacgttca ttcgatgtca cagaagctta ttatggcatg
     3001 gctatgcaat tattgacgta tctggacgta gcattgatgg atgcggtacg tttgactgga
     3061 aaggcggctg ttaaaccagc aggatcatat tatttacatg ttcataatcc tgtattgacg
     3121 gagacagatg atgtagagaa gaatacattg aaaaaattta gttatgatgg cgtttttgtc
     3181 gatgatcccg ctcttttaga agtactagat cattcactgg aagcaaaaga acaatcactg
     3241 atctatccag tgaaaaaaaa tgcgaaagat gaataccaaa aaggtagttt cagtaaagac
     3301 aaatttttca cggaagaaga actgcaacta ttcatggcgc ataatcggga aaatatgcgg
     3361 ttagctggag atgcgattac ttccggagaa atcaaactaa atccagctta taaagataaa
     3421 cagcggattg cctgcgaatt ttgtccattc agaagcatct gtacgtttga tgtgatgctg
     3481 aaagaaaata attaccaccg tctggagaaa atagataagg aagaagcact gcgtagaata
     3541 ttgaaaagga gtgaagaaga gtgaatcaaa ttcctttaaa accgcaaaat gaacgattca
     3601 cagatgatca gtggcaagcg atttttgatc aaggagataa tctattagtc tctgcgtctg
     3661 ccggatcagg taaaactaca gtgcttgttc gaagagtgat tgaaaaacta aaaatgggtt
     3721 ttgatatcga tgaattattg attgtgacat ttactgaagc tgccgcaaga gaaatgaaag
     3781 aaagaattca agaggcatta caagaatccg tcaatagcga aagtgaccct gtacgtagac
     3841 agcattttac taagcagtta gttttattgc ccacagcgaa tatctcaacc ttacatgctt
     3901 tttgcctgac agttattcga cgttattatt acttaattga tattgatcca gtctttcgca
     3961 tgttaacaga tgaaacagaa acgatcttga tgaaggagga tgtgtgggac gagctgagag
     4021 aagcacttta tgcagaaaat gatgaacgat ttttccaatt aacaatgaat ttttctaatg
     4081 atcgttcaga tgacggcttg acgaatctgg tgttttctct ttatgagttt gcccgtgcca
     4141 accctgaccc ccaaaaatgg ctagaacagt taagcgataa ttatcgtttg cctgaggggc
     4201 tagcgaaatc tcgattatat caaaaacaaa tccgtccttt agttttggca gatatatacc
     4261 aatgtgtaca gttatatgaa cagatgactc agttagcaca aggtgaagga ttagaaaaaa
     4321 tgcatgagca agtagctgga gaacaacagc agatcaagaa tatctatgaa gcgttctcgc
     4381 aagatcggtt agaagaagct tatgctggtt tggaacaact aactttttca acttttaaga
     4441 gcagtcggaa agcagaattg aaagaaattt ccaatgaagt caagggcatg agggataaag
     4501 caaaaaaact gattcagcag ataagtaaaa gttattttcc tgtttcccca agccaaatgg
     4561 aagaattaac ggacaaagca ctaccgttag tcgaagaaat gacaaaagtc acgcaaagct
     4621 tcatggacgg tttcagtatg cgtaaacggg aaaaaggtgt gctggatttc aatgatctgg
     4681 aacatttagc gttgcagatt ctcacagaaa aaacgaaaga tgtatggctg ccaagtgaag
     4741 cttcaaaaca ttatcgaaaa aaattcaaag aagtaatggt agatgaatat caagacgtga
     4801 accaattaca agaagccatt ttatactggc taagagaacc cgatgataca aaaggaaata
     4861 tgttcatggt tggggatgtc aaacaatcca tctattcttt ccgtttagca gatcctagtt
     4921 tatttatcgg gaaatacgag aatttctcaa agaaagaagg cggacgtcga atcgttttgg
     4981 ctgagaactt ccgctctaga aaagaagtcc tttcttttac gaatcttatt tttgaacaac
     5041 taatggatcc agcagtgggt caaatcaatt atgacgaagc agccaaactg atccaaggat
     5101 tttcagactt tccagagaat gaacagtttg agccggaaat catgatctat gaaaaagaac
     5161 aggaagaatc agagattgag attccgacgg atgatatact ggaagacaaa acagaaggcg
     5221 aactttttat gacaggacta aaaattcgtc aattaattga ttcctccttt atgatttatg
     5281 ataaaaaatc aaaaaaaagt cgtccgatag agtacaaaga cattgttctc ttgacaccta
     5341 caaagaagaa caacttaacg attttagaga ttttcaaaac attggatatt ccattagaga
     5401 tgaatgatgc tcaaaactat tttcaagcga cagaaattcg cacgatgatc tcgctgctac
     5461 aattaatcga taatccctat caagatattc cgcttgcggc tgtattgcgc tcaccgatcg
     5521 tgggtctgat tgaaccagaa ttagccagca ttcgattagc taaccgtgca catacttact
     5581 atgatgctgt gcttgcttat caagcatcaa acgaagatga attagcagct aagctggaac
     5641 attttggcaa gcaactagag cattggcgag aacttgctcg ccgttcttcg atcactgact
     5701 tgttatggga tatctattat gagacgggat atctagagta tgtggtcggt ctgccagcag
     5761 gggcacagag acaagccaat ctttatgcat tggttgatcg tgccaaagct tacgagcaaa
     5821 gttctttcag aggattatac cagttcgtgc gtttcattga aaaaatgcaa gaaaaagata
     5881 aagacttagc agaaccagtc atttcaatag aagataatgc tgttcgcgtt atgacgatcc
     5941 atgcaagtaa aggcttggaa ttcccagttg tatttttgtt agatatgaca aaggagttca
     6001 acttacaaga cttgcgcaat cggtatgctt ttgaagaaaa acttggagca ggaattcgct
     6061 atatggatcc tgaaacacga gtgttatatg atacgttacc gtttcaagcc atcaaattgg
     6121 caaagcaaaa caaattgttg tcggaagaaa tgcgtaaatt gtatgtagga ttgactcggg
     6181 cagaacaaaa gcttttcatt gtcggttcct ataaaaataa agagcaaatg atccaaacgt
     6241 ggtctgaagc agctgatcat gaggagttag tttttgatcc tgcgctacgt ttgaagggca
     6301 gaagcagctt gatgaattgg attggttacg gattgatccg tcatcctgaa atgcagaaat
     6361 acttagagga agaaatttcg acttctcttc ttcaacattc aaatgcacag ttttctattt
     6421 catggatgaa tcagcaatcg atcattgaac aaagacagtt gcttgctgaa aaagaactgg
     6481 ttaacttaga tcagcagatg aaagaagatg aaactttatt agcagattcg ttacaaaaac
     6541 gtctggcata tgaatatcct tatcaagctt cttcacaaac cacaagttat caatctgtat
     6601 ctgaaatcaa acgattattc gaagatccag atgatacaca agaatcacgt ttgactctgg
     6661 aaagcagtca gaacaaagca gcatcccgtc aatttcgtta tacgcaagaa caactagcag
     6721 aaccaaaatt tttgcaaaaa gatcggcaag tgtcagcagc tgctgttgga actgctacgc
     6781 atgctttgtt acaattactg ccattagaga tgccaactac agagagtatc catcaaaaat
     6841 tacaggaatt ggtaaggaaa cggttagtag acgaaaaagt cgcgaaaaaa gtagatgttt
     6901 cttctattat atggttcttt caaacagaac ttggtcaaca gctgattgcc aacaaagaaa
     6961 acgtaaaacg agaacaacct ttttccatgc tgcttcctgc tgacgaagta tttcaagact
     7021 atccaaatca agaagatgaa ctattaatcc acggaatcgt cgatggatac ctagaagaaa
     7081 aagatcatct caatatctat gattttaaaa cagattttat tttacatccg gatgatccag
     7141 cagaaataga tgcaatcgtc caaaaatatc aaggacagct aagactttac caacaagcaa
     7201 tgtcagaagc tttgaataag ccagtagaaa atgttttcct aattttgctt cgagtgaaac
     7261 aaattataaa cattaacaaa taattataat tgagcaaact tgacttatgt tttgtaagga
     7321 ttatgctata ctctgggaag aggtgagtat gatggagcta acacagacag aattcgtttt
     7381 atgccctaaa tttgaaaaaa cattctctat tttaggaaaa aaatggaacg gattgattat
     7441 cgatgtacta ctcgaaaacg gtccgcaacg ctttgttgag cttgcggcaa aaatcccgat
     7501 ggtcagtgat cgagtattag tcgaacgctt gaaggaatta gaaaaagaag gaatagtcac
     7561 tcgaaacttt gcctgtagcg aaaagagccg ttcagaatat ctcttgactg aaaaaggagc
     7621 agacttgcaa aaagcgatgc gtcaaataca agtttggagc gaaaaatgga tcacagagga
     7681 agaatgcggt tgattttgta aaaaaaatct tgtaaactat agtccatacg aataagtaaa
     7741 gaacgatgac gaaaaagagt agtttggcta aaccagttca gggagatctg tcgcagactg
     7801 aaagcagatc ctgtgtttga aaaatgaagt tcactttccg agttcgtctg ataaaatcag
     7861 accggcaatt gtcgttaacg aagtaagagt gcggtgtaag tcatttatcc gcaaattagg
     7921 atggtaacgc gaagacctcg ttccttaaca ggaatgaggt ctttttgttt tgtatttgga
     7981 atttaaagga ggaacaagca catgtctcta caagcacaat tagagagctt gaaagaagca
     8041 acgctcgtca aaatcacagc ggcacaagat ttaaatgaat taaatcaaat acgtgttgaa
     8101 acgttaggaa aaaaaggacc gatcacagaa gtattacgtg ggatgaaaga tctaagtcca
     8161 gaagagcgac caaaagtcgg aagtttcgca aatgagatcc gagatctttt gacagaagag
     8221 atcgagcgaa aaaaacaagt attagaagaa gaagcgttaa atgcagcttt ggcaaaagaa
     8281 acaatagacg tgacactacc tggtagaaaa gtaaaacatg gtacacgtca tatcgtgaca
     8341 caaatcatgg aagaaattga agatattttt gtgggtatgg gctatcagat cgtagaagga
     8401 tatgaagtag aatctgatca ttacaatttc gaacggatga atctgccaaa agatcatcca
     8461 gcaagggaca tgcaagatac tttctatatt tcagacgaga tattgattcg gacacatact
     8521 tcaccagtcc aagcacggac aatggaaaaa catgatttct ctaagggtgc tctacgaatg
     8581 atctcgccag ggaaagtctt ccgcagagat acagatgatg cgacccacag tcatcagttc
     8641 catcaaattg aagggctagt tgttgataaa aacatcacaa tgggcgacct taaaggaaca
     8701 ttagaagtcg taatgaaaaa aatgtttggg gaagatcgtg aaattcgttt gcgtccaagt
     8761 tatttcccat ttacggaacc atcagtagaa gtagatgtca gctgtttcaa atgtggtggt
     8821 gccggttgta acgtatgtaa atacactgga tggatcgaaa ttttaggagc tggcatggta
     8881 cacccgaatg tgttgaagat gtcaggaatc gatccagaag aatattcagg ctttgctttc
     8941 ggccttggac cagaccgcgt agctatgttg cggtatggag tgaatgatat ccgtaatttc
     9001 tatcaaaatg acttacgttt cttaagtcag ttcaaggggg agtaagaaaa tgttagtttc
     9061 atataaatgg ctcaatcgtt atgtagattt atcgaatgta acaccaaaag aattagcgga
     9121 taagatgtct gtgacaggaa tcgaagtaga gggagtaacg gttccagaag aaggcttgaa
     9181 aaaaatcgtt gtcggtgaag tcaaggaatg cgtaccacat ccagattctg atcacctttc
     9241 tatttgtcaa gtcgatattg gcgaagacga actgtctcaa atcgtttgtg gagcgcctaa
     9301 tgtgaaggtt ggaatcaaag tgattgttgc acttcctaac tcacgtatcg ctggtaatgt
     9361 aaaaatcaaa aaaggaaaaa tgcgtggcca agtatcaaat ggcatgattt gctcattaca
     9421 agaaattggc tattcagata gtgttatacc gaaagaatac gctgaaggta tctattatat
     9481 gccacaagaa gctgtaaatg gcgatccagt ttttccttat ttggatatgg atgattcgat
     9541 tattgaatta tctatcacac cgaatcgtgc ggatgcattg tcaatgcgtg gcgtagctta
     9601 tgaagttggg gcaatttatc gtcagactcc tacattcgat gacgaaaagc tggtagaatc
     9661 ctcacgtcct gctagcgata aaattcaagt ggaagttgaa gataaagaag cagttcctgc
     9721 ttatcaaatc agaatcattg aaggagtaag aatccagcca agtcctcaat ggctgcaaaa
     9781 tcttttgatg aacgaaggca ttcgtccaat caacaatgta gtagatgtga cgaactatat
     9841 tttgctttta ttcggacaac cactacatgc atttgactac gacaaattga aatcaaaaga
     9901 gatctttgtc cgccgtgcaa aagaaaatga aacattagta acactagatg gagaatctcg
     9961 ggaattgaca actgacaatc tcgtcattac taacggcaaa gaaccagttg ctttagctgg
    10021 tgtcatggga gggttagact cagagatcac gaatgaaaca acaacagttg cactagaatc
    10081 tgctttattt gatccaattt cgattcgtcg tacagcaaaa caatttaatt tgcgtagtga
    10141 atcctctgca cgttttgaaa aaggaatcaa ccatgcgact gttggagaag ccagtgaggt
    10201 tgctgcagca atgatcgttt ctcttgcggg tggggaagtt ctacaaggcg cggtcaaagg
    10261 ctcagagatc aaagcagaag acgtatcagt gaagatttca cttgaacgca tcaatcaata
    10321 tttaggaaca tctcttgtcg ttaaagaagt aaatgagatt tttgaagcac ttggatttag
    10381 ctatgaagaa aaggagtatg tttattccgt agtagtacca ccaagacgct gggatatcca
    10441 aatcgaagca gatattatcg aagaagttgc tcgtatttat ggatacgacc agttgccatc
    10501 tacacttcca agtggagaaa cggttgctgg aagcttgtca aaagaacaag aaactactcg
    10561 taaaattcgt acaatctttg aaggaagcgg attgagcgaa gcaatcagtt atgcattgac
    10621 aacagaagaa aaatcaagac agtttgttat aaatgaaagt aatattacac gtttggactg
    10681 gccaatgagc gaagaacgtt ctgtattacg aatgaatttg atcagcggac tattagatga
    10741 tatcagttat aacactgccc gaaaaaatac agagattgct ttatatgaaa ttggtcgggt
    10801 gttcttccaa gaaaatgatc cacgtacaca tctgccgcaa gaagtaaaac atgcagcaat
    10861 cgctatttct ggtatttggg aagaaaaaga ttggcagacg aaagctcaaa atgtagactt
    10921 tttcaccatc aagggtcttt tagaaaactt atttgaacaa ctaggcatca ctgaagatgt
    10981 ccattatcaa acagtgacag aaatgaagga aatgcatcct ggaagaactg ctgcgattta
    11041 ccttggcgaa aaatttattg gttttgtcgg tcaagtgcat ccaacgatta caaaaagtta
    11101 tgatattcca gaaacatatg ttgctgagtt tgatttatct gctatagtgg aagctgctca
    11161 aaaagggatc gttttcgaag cagtgacaaa attcccagca gtcagccggg acatcgcttt
    11221 gcttgtaaaa gaaactgtga caaatcagga attaacagaa gttatccgtt ctgctgccgg
    11281 aagattttta acagatatcc aattatttga tgtctatcaa ggagaaaaca ttgaaaaagg
    11341 acataaatcc atggcgtata gcctgacatt cgtcaaccca gaagcaacat tgacagatga
    11401 agaaatcaat aaagcaatgg aaaaagtcga aaaagcgttg gtagaaaacc tagaggcaag
    11461 tattcgctaa gaaggaaaat atagtaagta acgatcaagt agcttttgaa gaccatacat
    11521 ttgaaaaaaa gatgtgacac aacttcgtca catctctttt tttgatttta aaaaaggaat
    11581 agcacagaga cgagataaaa aaacaggcct ttacagcctg cttttttaga gtaaatgaat
    11641 taatggaagt aattgattcc cattgctgat tttacttcag aaagtgtttg tgcagctact
    11701 ttagcagctt cttcactacc tttacgtaag atttccataa cagctgaagg atctttttcc
    11761 aattcttctc ggcgcgcacg gatcggtgca aattcagctt ccaatacatc aatgaggtat
    11821 cgtttgatct ttacatcacc aagtccgccg cggcggtaat gagctttcat ttcttcaatt
    11881 gcttctttat ctgttccgaa tacatccaag taggtgaaga ccatattccc ttctacttgt
    11941 ccaggatctt gtacatggat gtggtttgga tcagtataca tactcatgac ttttttctgt
    12001 aagacatcgg caggatcgga gatataaata ccgtttccta acgatttact cattttgcca
    12061 tttccatcga ttccaggtaa tctacccatt ccttttggtg ggaatacgcc ttttggttcc
    12121 accaagactt caccatatgt atgattgaag ctttgtacga tttcctgtgt ctgctctagc
    12181 attggttttt gatcctcacc aacaggtaca agattcgctt tgaatgcagt gatatctgct
    12241 gcttgagaaa caggatagat aaagaatcct gtaggcacgc tttcaccgaa ttttttttgt
    12301 tcgatttctg ttttgacagt cggattgcgc cgaacgcgtc ctacgctgac taagttcaaa
    12361 taatacatgg ttaattcagc taattccgga atttgtgatt ggataaataa agtagatttt
    12421 gcaggatcta atcccacggc taaatagtct aaagcaactt gcaagacatt tgatgaaacc
    12481 ttctcaggat ttttagcatt atctgtcagt gcttgcatgt cagcaatcat gacaaacagt
    12541 tggttgtctt catctgcctg catagccact cgggttttta gagaaccgac gtaatgccct
    12601 aaatgcagct tcccagttgg tcgatctccc gttaaaataa tatttttcaa aaaagacacc
    12661 tctttacgat ttgtaagtct gagcacttaa tatcttaccg tttttcctga aaagaaacaa
    12721 cagttcctaa ggaaaaaaca aggaaagagg ataaaataac taatagatta gaaatggaag
    12781 aaatatttat gggagaataa acgttctaag aaactttaca aattactaaa ctatcagata
    12841 taatgtattt tattatacat ctttaaaaga aatcttacta aataataatg ggagtgtaat
    12901 tctatggcaa tgattaaatt tgatcacgtg gataaatatt atggcaagtt ccacgcatta
    12961 aaaaatatca atctcgaatt cgagaaagga gaagttgtcg ttgtcattgg tccttctggt
    13021 tcaggaaaga gcacgatgct tcgctgtatc aatggattag agacgatctc ttcaggtaag
    13081 ctgctgatta atgatactga cttgcatgat aaaaagacaa aactgacaga agtccgaaaa
    13141 aacatcggca tggttttcca acatttcaat ttgtacccaa ataaaactgt tctggaaaac
    13201 atcaaattag caccaatcaa agtgttgaag caagaccagg caactgcagt caaaaacgcg
    13261 gagaaatttt tgaaaactgt caatatgtta gataagaaag attcttatcc ttccatgtta
    13321 tccgggggac aacagcaacg ggtggcaatc gccagaggtt tagcgatgaa tcctgagatg
    13381 ctgctgtttg atgaacctac ttctgctttg gatccggaaa tgattggtga tgtattagac
    13441 gttatgaaaa aattggctca tgacggtatg tcaatgattg tcgtgacaca tgaaatgggc
    13501 tttgccaaag aagtggcgga tcgtgttatc ttcatggctg atggagaagt attggaagac
    13561 agcagaaatg tgagagactt tttcgaaaat ccaaatgaag tccgagcaca gcaatttatc
    13621 agtaaagtta tcaatcattg ataggaggaa aaagatgcgc aggttaaaaa aaatacgcct
    13681 gattttcctt ttaggcattg cttttcttgc actagccgga tgtaaaggaa atgggttggc
    13741 aaatgaagat attttagagc gaagcaaatc taccaatgaa atcatctggg gtgtcaagta
    13801 tgatactcga ttatttggaa tgatggatat tgagagcaga actgtacaag gatttgatgt
    13861 agatattgca aaagcaatca ctaaaaagat ccttggtgac aatggaaaaa cagaatttgt
    13921 tgaagtcact tctaaaactc ggattccatt attgaaaaac ggaaatatcg atgcaattat
    13981 tgcaacgatg acgatcacag atgaacgaaa aaaacaggtt gacttttcag atgtctattt
    14041 cgatgctggc caagctttgt tggtaaagaa aggaagccaa atcaaaagtg tagatgattt
    14101 gaatgcttct acaacggttc tagcagtcaa aggttctaca tcggctgcga atatccgaca
    14161 gcatgcacca gatgcaaaaa ttttagaatt agaaaactat gcagaagcat ttactgcttt
    14221 acaatctggt cagggagacg cgatgactac ggataatgcg attttgttag ggattgcaga
    14281 tgaaaatcca gagtatgagt tagttggtgg aacgtttact aatgagcctt acgggattgc
    14341 gatcaacaaa gggcaagaaa acttcttgaa agctgttaac caagcgctag aggaaatgca
    14401 tgcagatggc acatacgata aaatctatca aaaatggttt ccaaatgaaa ctgaaggaaa
    14461 agtagagtaa gggggagagg caatgagcga attgatacaa acttatggac caatctttgt
    14521 cgacgggttc aagatcacat tgttttcgag tgtcttagca cttgtgttta gtttgattat
    14581 cggaacgtta atggcaatct tccaattatc aaagaataaa gtagtgagcg ccttagcaaa
    14641 ggcatatgta gaatttttta gaaacattcc attattaatc atcgtgatgt ttttttatgt
    14701 tgtcgtaccg atttattggt ttaatctaga tggattccaa gcaggtacga ttggattaac
    14761 gatctataca tctgctttta ttgctgaaac agtacgttca gggattcaaa ccgtaccaaa
    14821 aggtcaaaca gaagcaggac tatcttctgg ttttacctat tcagaaatca tgcgttatat
    14881 tgttttaccg caagcattca aaatcgttat cccgccatta ggcaaccaat ttatcaacct
    14941 cgtaaaaaac tcatctattt tagcaatcgt agctggttta gatttgatgt atcaaggaga
    15001 cttgatcgct agtgaaacat tcaatacctt cgatacgtat atcatcgttg ggttatttta
    15061 cttagttatc acgctaccgt tatcttactt aatggtttat cttgagaaaa aatgggcggt
    15121 tcgttcatag aaggagggga aatacatgga ttttagcggc gctttttcat ggatgaatat
    15181 ccgtttttta ttggaaggat taaaggttac tgttgaagtt tcattgtttt cgatcatttt
    15241 tagtttcttg atcggtggtc tgacaggtgt gattcgtttt gcgaatatcc ctttcttttc
    15301 caaaatcctt ggtgtagtga ttgatattat acggaatctt ccattattat tgatcatttt
    15361 cttcacttac tttgccttac ctcaaatcgg cattcagatg aacatcttct ggtccgctgt
    15421 cgcagcatta acgatttttg agtcagctat gttgtcggaa attttccgag ctggactcaa
    15481 tgctgttcca aaaggacaga tggaagcagg attatcaacg ggactgactt atgtagaatc
    15541 gatgcgaacg atcgtgttac cgcaagcatt taaatcaatg atcccggcaa ttgtgagcca
    15601 attgatttca ctgatcaaag atacttcatt agcagtaatc atttctttac ctgaactttc
    15661 tcatcaggca cgtattattt atggacagaa caccaattat gtgcttccga tgttcatcat
    15721 catgacactt atgtacttcg tggtatgtta cgcgctttct ctgctttccg gttacttgga
    15781 aaagagacgg tacagttatt aatagatgat tcttttagcg gttgtggcaa actaaagtca
    15841 caaccgcttt tcctctttcc attcgaaaaa aagagatttc gattgtttta agcaagtaag
    15901 agcacttgaa aattcacgct aaaaagtaca caatagggag gatagaattt attgaaaaaa
    15961 aggatgatac gattgacaga taatcgccct atcggattta ttgattcagg tgtcggcggc
    16021 ttgactgtag taaaagaagc cctgaaacaa ttaccgaatg aaaatatttt atttgtagga
    16081 gacacagcac gctgcccata tggccctaga cccgcggaac aggtaatcca gtatacttgg
    16141 gaaatgacgg attatctggt ggagcaagga atcaagatgc tggtgatcgc ctgcaatacc
    16201 gcaactgcgg tggctttaga agaaatcaaa gctgctcttt ctattccagt catcggtgtg
    16261 atccttcccg gtactagagc ggcagtaaaa aaaacacaaa ataaacaagt tggcattatc
    16321 ggtacgattg gtacggtaaa aagtcaagct tatgaaaaag cactgaaaga gaaagtacca
    16381 gaattgactg tgacaagtct tgcttgtccc aaatttgttt cagttgtcga aagtaatgaa
    16441 taccattcat cggtggcgaa aaaaattgtg gcagaaacat tagctccttt aaccactaaa
    16501 aaaatcgata cattgatttt gggatgcacc cattatccat tattacgccc catcattcaa
    16561 aatgtaatgg gagaaaatgt tcaactgatc gattctggag cagaaacagt aggtgaagta
    16621 tctatgctgt tagattattt caatttgagc aattcaccgc aaaatggtcg gacattatgc
    16681 cagttttata caactggctc tgccaaactt ttcgaggaaa tagctgaaga ctggcttgga
    16741 atcggacact taaatgtaga acatatcgaa ttgggaggaa aataaggatg cgtcatgacg
    16801 ggagaaaagc ccaagagctt cgcaaactgg agcttcaaac aaatgttttc aaatatccag
    16861 aaggatcggt agtgatccgt tttggtgata caacagttat ttgttctgca acaatagaaa
    16921 attctgttcc cccttttttg agagaaacag gaacaggatg ggtgacagca gaatatagta
    16981 tgctgcctcg agcaacgagt acgagaaatc gtagagaaag cagcaaaggg aaactttctg
    17041 gtagaacaat ggaaatccag cgtcttattg gtcgttcctt gcgtgcagta gtagacttgg
    17101 aaaaattagg agaacgtagt atcatcgtag actgcgatgt gatccaagcg gatggcggta
    17161 ctagaacagc aagtatcact ggggcatttg tggcattgaa attagccatt gaaaaacttt
    17221 taagagaaaa agaattgtca gaagatccaa taaaagaaca tcttgctgca gttagcgtag
    17281 gaatcttacc agatgggact tgcgtcacag atttggatta ccaagaagat tccgcagcac
    17341 ttgtagacat gaatcttgta atgacagaat ctggaaaatt cgtggagatt caaggaactg
    17401 gagaagaagc aacgtttgat ggtgaacagt tgaatgaaat gctctttttt ggaaaaaacg
    17461 cgattgaaga tttgatcaaa gagcaaaaac atgctttgct aacagagttt gctcaaaatg
    17521 atgagcggat agaagaaaca aaaacaatca tcattgcgac aagaaatcca ggaaaagcag
    17581 aagagtttcg aaatatgttc aaagaagcgg gatatcatgt aaaaacatta cttgactatc
    17641 ctgaattgcc agatgtggaa gaaactggca gcacatttga agaaaatgcc cgattaaaag
    17701 cagaaacgat tgcacaattg cttgatcagc cagtcttagc agatgattca ggtttgaaag
    17761 tggatgcttt aggcggtatg ccaggaatct attctgcacg ttttgcaggg gaacaaaaaa
    17821 gtgatgcggg gaataacgcc aaattattat atgaattgac agatgtgccg gatgaaaaaa
    17881 gaacagcaca attccattgt acgttagtat tcgcggcacc caaaaaagac agccttgtag
    17941 tagaagcgga atggcccggt cgagtagccc gtataccatc tggcgaaaat ggctttgggt
    18001 atgatccttt atttatccca gaaggtaaga aacaaacagc agcagaatta tcgagcgaag
    18061 aaaaaaacaa gatcagtcat cgggctcaag caatgaaaaa attgagtgcc gagtggaaac
    18121 aatggctgga aggagagaga tagatgcggt atttagtagt aagtgataat catggagaca
    18181 gagatatcct cgttgactta gtagatcgtt atcgttctga agtggatatc tttttccatt
    18241 gtggtgattc ggaattagaa gcttctgacc cattatggga tacattccaa gtggttcaag
    18301 gtaattgtga ttatggacca ggattcgaac agaaaaaagt gatccaaact ggtcaggata
    18361 cagtattcat gactcacggt catttatcga atgtccgatt tggtttgaca cagttagcaa
    18421 tcgaagctcg agctgcaact gccgatatgg tgttttttgg tcatacccat caaataggct
    18481 gtgagatgga tcagaaaatc ctgtttttga atcctggtag catttctcag cctagaggcc
    18541 cgatccaaat cccatcatat gctcttatcg aaagtttaga tgaccaaatt tctgttcaat
    18601 actataaccg tgcccatcag gcagttgaag agttggcctt ttctttttcg agagagcgct
    18661 gaataaaaaa actctaattt ttaataaaaa taagctttat tttatgaatt ttgcatccgg
    18721 tttcggtaaa atagtagtgt tgaatgaaat agaaatggag gccatcagat gattggacct
    18781 atagtaagag aaatgctgct ggaaaatcag gaaacgtttt tgattcctgc agaaaatgtg
    18841 gcaaatgtta tgtatcatca tccattgtcc catggtttac ttgtgttatc gaaggtcggt
    18901 tattccaaaa ttcctgtatt aggaaaagat gatcactttg taggactagt aagtttatca
    18961 gatgtggtca ataaaatgat tgacttgcaa acaatcagca tggacccgtt agaaggacta
    19021 acggttgctg atgtgacaga aacagatgtt ccgacaattg atgaaaattg ggaactagaa
    19081 gaagtactcc atttgttagt cgattcgcct tttttaccgg ttgtcacaga agatcggatt
    19141 ttcaaaggaa tcattacaag aaaagagctg cttaaagccg taaacttcat ggtgcatgaa
    19201 ttagaacgtc gtaatatatt gtctccgaaa atcgaagaat taaaagaaca aatcgatatc
    19261 gtgagctaaa gaacgagaaa ctaaaagata atcaaaaaat aagtagaaaa aacagcgtac
    19321 cagttttgac tttatcttga aaaagaggct gggacaaaag cgtttaactc caagaaataa
    19381 gaaggaattc acgaaaattg cttttcaaat ttttgtgaat ttcagcttat ttccgaagga
    19441 gttgcttctg cttccgccgt ttatacgtgt ttagagcgtg ggacaaaagt gttctttact
    19501 tttgtcccac gctcttttta gtgagattcg ttgcatcgtt tgtccaaatt attttccgac
    19561 agcaattgga ctgttcggaa tcgtgaaacc agaagctgtc aattctttga cataggagct
    19621 caagaactct tcttttaagg catattgttt tccgttcaat gcgtagcaga ccgtacgaat
    19681 cgcaaaattg ctgtttccaa gatccactaa tccaaagata gaaggttcag tttggagctc
    19741 ttcttggtat ttttcagcta atgtacgatt tactcgatca atgatctcat agattttgtc
    19801 atatccttct tcaggaacaa tccgaatatc taaaagtact tgcatatttg cacgagagag
    19861 attgctgatc gtggtgatgt ttcgattcgg gatgaaatgg acagtaccat ccgttgcttt
    19921 cagctgaagg gtacggatac caacagatac gacggttcct tcaatcgtta agtttgctag
    19981 cttgatgtag tccccaacat ccatctgttg ttccatgata ataaaaaatc cggtaataac
    20041 atcactcatg aacccttggg caccaagacc gattgccaca cctgcaattc cggcaccagc
    20101 caaaagtgat ccgatcggca caccgatagc agataaaatt gcatagataa aaaagaaacc
    20161 aagggtataa tgaaaaatag tatttaaaag actatgtaaa gtctttaagc ggctctcgtt
    20221 tagaatggct tttttagaat actgattaaa agacttatca atcagatatt ttcccacacg
    20281 gtgaagaatc caaaaaagga cgatcaaaaa aatcagatat aaactttttt ggataaaggc
    20341 agccaaaatg gcgtcccaat caatcccgtc ccaaaaccgc tgaaacgcat ttactttgct
    20401 gacagcttga tctgtcaatg tctcgccaga agagtctgtc gtaccggcag ttgctaataa
    20461 tgaaaacata aaatcctctt ttctaaaatt tgattctttc tgtattgtac caagaagttt
    20521 tcaaaaaagg aaatagcaaa aataactata atgaaggaaa aaagctgaaa ataaaatgac
    20581 aaataatatg gataatgata aaatgtggag aaaataacga aggtggtaag tatatgcaaa
    20641 tcgattggaa caatctaggt ttttcttata tcaaaactcc ttggcgtttt attgccaaat
    20701 ggaaagacgg acaatgggaa gaaggagaat tgacagaaga taattacctg acgattcatg
    20761 aaggctctcc agcgcttcat tatggtcagc aatgttttga aggtctaaaa gcttatcgtc
    20821 gaaaagacgg caaggtcaat ctctttcgac ctgaacaaaa tagtcgacgg atgaatcaaa
    20881 gtgctagacg attgctgatg ccaatggtcc ctgaaaagat gttcgttgat gctgtcaagc
    20941 aagtggtaaa agcaaatgaa gattttgtgc cgccctatgg aacaggcgct acattatact
    21001 tgcgcccttt actgattggg gtcggtgaaa acattggtgt ccatccagct ccagaatatt
    21061 tatttgtcgt cttctgtacg ccagtaggag cgtatttcaa aggtggacta aaaccaacga
    21121 attttattgt atctgattac gatcgtgctg ctcctaaggg gactggtgca gcaaaagtcg
    21181 gcggaaatta cgcagcgagt ttacttccag gaacagaagc aaaagaactg gattactcag
    21241 attgtgttta tcttgatcca gccacacata cgaaaatcga agaagtaggt gcagcaaatt
    21301 tctttggaat tacaaaagac ggaaaattca tcactccgca atcgccctct atcttaccaa
    21361 gtatcacgaa atattccttg ttgcagttag ctgaagaacg actaggactg caagcaattg
    21421 aaggagatat tttcattgat gatctagatc aatttgcaga agctggtgca tgtggtacag
    21481 cggctgttat ttctccaatc ggtgggattt atcacaataa caatcttcat gtattttata
    21541 gtgaaacgga agtaggacca gtaacaaaac ggttgtatga tgaattgaca ggtattcaat
    21601 ttggagacat agaagcacca gaaggctgga ttgaagtcgt ggaataattt caaagtaatg
    21661 agttgaaaaa aacgtaaaaa gaaaaaatca ggaagagact ttaaaaagtt ttttcctgat
    21721 ttttatatgt tttactttaa agaatgcaac aaaagtttat gaaagatgga cacctttgtc
    21781 aacgtagata atatcaccga tgattccgct ggaaagtggg ctgattaaga aagcacaagc
    21841 attaccgact tcttcgatcg tcacaccttg ctgatcaggc gtacgagatt cagataactg
    21901 gatcagtttt tgatagtctt taacacctgt gacagctaat gttttgattg ccccagctga
    21961 gattccattg acccgaattc ctttaggcga gaactcagct gccaaataac ggatagcagc
    22021 ttcaagagaa gctttcgcaa tacccatcat gttataattc gggattgcgc gttctgaacc
    22081 tagataagtc atgctaacga tcccgctgtt tggtgcaaga aacggttgtg cgtattttga
    22141 tacagcaatt aaagagtagc tgctgatatc ttgagctaat tgatagccgt ctctggaaat
    22201 atcagacaca tttccggaca attcttcttt gttggcgtaa gcaactgcat ggacaaggcc
    22261 gtggatctcc ccagcatatt caccgatggc attcattgct ttttcgatgc tttcgtcgct
    22321 agaaacatca cattctacag tgaatgcttc ttcgccgacc aatttgacta atgatttttt
    22381 cattcgttca ttttggtaag tatagataat ttctgcccct tgtttcaaca ttgcttcagc
    22441 acaaccccaa gcaatgcttt ttttgttagc gacgcccata atgacgattt tttttccttc
    22501 tagaaatgac ataatgactc tcctttgttt ctgataaaaa tttgatagtc gtaaaaaaat
    22561 agagaataat agctaaaata acttcttgat ttcttaatta ttagtcaaaa tgttttgatt
    22621 gtcaaactat tttttcttaa attaaaaaaa gattgctaaa tatttaggaa tatgatactt
    22681 tgatagtcaa agtaatgaaa atggcaattg cctgaaagaa ggagtttaat tatgtcttac
    22741 gtattatctg ctactgaagt aatggaattg attcctaatc gttatcctat ttgttatatt
    22801 gattatgtag atactttaga accaggaaaa aagatcgttg cgacaaaaaa tgtaacaatc
    22861 aatgaagatt ttttccaagg tcactttcct gacaatccag tgatgccggg tgcgttgatt
    22921 ctagaaacac tggcacaagc aggttcgata cttatcctaa aatcagaaga gtttctagga
    22981 aaaagagctt atatcggtgg gatcaataag gccaaattcc gtcaaaaagt tgttccagga
    23041 gatgtgctga aatgtcattt tgaaatcacc aaaatgaagg gatcagtcgg tacagcgtta
    23101 tctgcagcat atgtagatga taaaaaagtc tgtgagtgcg agttcacgtt catcgtcaac
    23161 caaaatgctt gactataaaa cctgatatag caaaacaaaa ggaagcttac ttgcttttta
    23221 tgtaaaaaga agacgcctga atcctagcat acgttgtcat ctatgcagga ttcagacgtt
    23281 atttttttat ttttgttttg cttcttgcag tatattgatt ttatcgattt ttacttcttc
    23341 ttttggtttg tctgaactat ctgtttcgat atttgcaata gcatccacga catccattcc
    23401 ttcaatcact tggccgaaga cagtataatg gccatctagt gaaggataac cgccgttttt
    23461 ataagcgtcg atgattgctt gaggatagtc gtcttttaaa agaccatcat gcatatcatc
    23521 tgtattttga acgataaaga actggctgcc gttactgtta ggatcttgtg agcgagccat
    23581 agataacgca cctcttatat tataaaggtg gttgttgatc tctgtttcaa atccttctcc
    23641 ccaaatgctt tcccctccag tgccatcgcc tttaggatcg ccaccttgga tcatgaaatc
    23701 tttgatgacg cgatggaaag tcagtccgtt gtagtaaccg tcttttgcat gtgtcataaa
    23761 gttttcaacc gcttttggtg cgtgttcggg aaataatttg attttgattg tgcctttatt
    23821 cgtcaccatt tcgaccagat cttcattttc ggcgacatct ttcgtcaatt gtggtaattc
    23881 caatgcgttc aaatcgacgc tactggcagt cgtgctttcc gcagtagatg tactttttga
    23941 actttctgta gacgaactag aagaagtcgt gttgtttgca gaacaaccag cagcaaacag
    24001 caatgctgct gctaaactaa tacttaaaat aactttattt ttcttcataa ctgttccttt
    24061 ccaatttact attttgttat ctttaatgat aacaaaatag agggaaaata cctacttaaa
    24121 ttattggaat ttatcattta ttttaaaaga aaaagaaaag gtgtagacca tttactttgt
    24181 gtttgctata atgtaagtgg atacaaaaac gaaaagatgc aggaggaaat ggtaatatgg
    24241 gaaaattagg aatctcgatt tatccagaac ggtcaacatt tgaaaaggac aaagcgtact
    24301 tggatttagc tcataagtat gggtataaac gggtttttac cagtttgctg cagatcaatg
    24361 atgataaaga aaaagttctt tcagaattta aagaagtagt tgattacgcg aatagcctag
    24421 gcatggaagt aatggttgat atcaatccag cgttatttga acagttggag atttcttacg
    24481 atgacttatc ttttttccat aagatgggtg cctacggggt ccgcttagat atcggattca
    24541 caggagcaga agaagcaaaa atgacgcgca atccttttgg tatcaaaatc gagatcaata
    24601 tgagttcggg cacgaattac gttgacaaca tcatgagtta ttcgccaaac acggataatt
    24661 tattaggttc tcataatttt tatcctcatc gatactctgg tttaggatac gaacactttg
    24721 ttttttgttc agaaaaattc agaaaatata atttgaatac gatggcattc gtcaattcgc
    24781 aatctgctga gtttggccct tggcctacgc aagatggctt gtgcacgctg gaagaccacc
    24841 gagatcttga aattgcgaca caagtgaagc atttaatcct tacaggattg attgatgata
    24901 tttctattgg aaatgcgtac gcaagtgaag aagaattgaa agaaatggca gaagcattta
    24961 acgcggatta tccaacattg aaagtagata cggaagaagg tattacagaa aacgaacgaa
    25021 tctgcttgtt tgataacctt catagttatc gaggggatcg ctcagaatat atccttcgtt
    25081 caacgatgac tcgtgtatac tacaaagata aagatttccc gcctcataat acgcgagata
    25141 tgcatcatgg ggatgtactg attgacaatg aagggtacgg tcaatacaaa ggagaaacac
    25201 aaatcgcctt gaaggatatg aaaaacgacg gacgtgtcaa tgttgtagga agaatctccg
    25261 atgacgaatt attcctcctt gactttttga aaccatggtc aagctttaaa ttaattgaaa
    25321 ataaaaaata gataattagt tattgcagaa ataatccgct agaaatagcc agttatttct
    25381 gcttttttat tttgtttttt tatag
//
LOCUS       DAFKHN010000037        24570 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFKHN010000037 DAFKHN010000000
VERSION     DAFKHN010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.037"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(149..547)
                     /locus_tag="LY912_001521"
     CDS             complement(149..547)
                     /locus_tag="LY912_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBM6955225.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(544..1317)
                     /locus_tag="LY912_001522"
     CDS             complement(544..1317)
                     /locus_tag="LY912_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBM6955226.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1314..1997)
                     /locus_tag="LY912_001523"
     CDS             complement(1314..1997)
                     /locus_tag="LY912_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBM6955227.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2164..3051)
                     /locus_tag="LY912_001524"
     CDS             complement(2164..3051)
                     /locus_tag="LY912_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6955228.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3048..3917)
                     /locus_tag="LY912_001525"
     CDS             complement(3048..3917)
                     /locus_tag="LY912_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6955229.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4054..5340)
                     /locus_tag="LY912_001526"
     CDS             complement(4054..5340)
                     /locus_tag="LY912_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBM6955230.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5613..6191
                     /locus_tag="LY912_001527"
     CDS             5613..6191
                     /locus_tag="LY912_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBM6955231.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6191..7120
                     /locus_tag="LY912_001528"
     CDS             6191..7120
                     /locus_tag="LY912_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955232.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7117..8853
                     /locus_tag="LY912_001529"
     CDS             7117..8853
                     /locus_tag="LY912_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBM6955233.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8916..9752)
                     /gene="pheA"
                     /locus_tag="LY912_001530"
     CDS             complement(8916..9752)
                     /gene="pheA"
                     /locus_tag="LY912_001530"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBM6955234.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9749..10258)
                     /locus_tag="LY912_001531"
     CDS             complement(9749..10258)
                     /locus_tag="LY912_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBM6955235.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10251..11546)
                     /gene="aroA"
                     /locus_tag="LY912_001532"
     CDS             complement(10251..11546)
                     /gene="aroA"
                     /locus_tag="LY912_001532"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBM6955236.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11559..12650)
                     /locus_tag="LY912_001533"
     CDS             complement(11559..12650)
                     /locus_tag="LY912_001533"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBM6955237.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12667..13833)
                     /gene="aroC"
                     /locus_tag="LY912_001534"
     CDS             complement(12667..13833)
                     /gene="aroC"
                     /locus_tag="LY912_001534"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBM6955238.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13835..14899)
                     /gene="aroB"
                     /locus_tag="LY912_001535"
     CDS             complement(13835..14899)
                     /gene="aroB"
                     /locus_tag="LY912_001535"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBM6955239.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14932..15954)
                     /gene="aroF"
                     /locus_tag="LY912_001536"
     CDS             complement(14932..15954)
                     /gene="aroF"
                     /locus_tag="LY912_001536"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBM6955240.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16613..17587)
                     /locus_tag="LY912_001537"
     CDS             complement(16613..17587)
                     /locus_tag="LY912_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBM6955241.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17568..19451)
                     /locus_tag="LY912_001538"
     CDS             complement(17568..19451)
                     /locus_tag="LY912_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBM6955242.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19469..21694)
                     /locus_tag="LY912_001539"
     CDS             complement(19469..21694)
                     /locus_tag="LY912_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBM6955243.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21809..22843
                     /locus_tag="LY912_001540"
     CDS             21809..22843
                     /locus_tag="LY912_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6955244.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22910..23923)
                     /locus_tag="LY912_001541"
     CDS             complement(22910..23923)
                     /locus_tag="LY912_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBM6955245.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24001..24189)
                     /locus_tag="LY912_001542"
     CDS             complement(24001..24189)
                     /locus_tag="LY912_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBM6955246.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7059 a         5340 c         4396 g         7775 t
ORIGIN      
        1 tattttgaaa agaaagtctg atgcttagag tagaatttca taaaaattta ctatttcata
       61 agtattcacg agaaaaatac aaacaaaaaa gcggaaataa cgctcatccg ccttcttgtt
      121 tgtgtttatt tcctcttcaa acgcttgtct atgattcaga cttttctcta tcgttatttt
      181 catctaaaag ttcttgcatt ccgataattt ctcgatattg atgaatctta gtgataccaa
      241 tgactttgtc tacatcaata ctaaaacaaa taccattacc tggaatatcg atgttgatgc
      301 cttgaccaat cgcatccatt actttattcg tcaaactatc gggtactaat gtcaacacaa
      361 tatctttttc tggcgaaatg tccaaaccta aaaatttccc tgaatcatgt acaccagaac
      421 ctcttccatg taagatcgtt ccgcctgctg cacctgcttc ttttgaaaag tcgataacat
      481 cttcgcccat tcctccgtca acgatcgtca caatcatgtg aagattcaat gctacaagat
      541 ctttcatttg ctttccccca atttttgcaa tctttctttt tcgattctgt ctttttcatc
      601 ttttcgttta taaatatatc ctagtactaa agtggataat attggtgtca atgcaatcat
      661 tgcaaccaca ccaaacccgt caatgatcgg atctcttcct tcaatttgtg cagcgattgc
      721 cacgctcatt gataaaataa atgtcgaaca catcgggccc gttgctactc caccgttatc
      781 aaaagccatt gctaaaaaga tcttgtccac ttttcgtcct aaaataaatg ctagcccgta
      841 tcctgggatc aagaaataat aaagagagaa tccgacgagc aaacgccaca tagacaatcc
      901 tactgctgcg ccgatcccaa ttgaaattac catcagcatg attttcgatc ggattctccc
      961 ctcgctcaat tcttcaacct gtttgatcat tacatgaatc gccggctcag caaaccctac
     1021 taagaacccc attaaaaagc caaggggaac cagtatataa ttgtaaggca atcccgcaat
     1081 agcactgcct aaatgctgtc ctaccggtac ataagccata ttgactccgt gcaggaaaag
     1141 gatcaaccca atagtcgtta tcaagaaacc tttcataatg tcaaagaaac gctttttgcg
     1201 catacgaaaa ctaatgatat tcattaaaac aaataggatt acgataggtg ccactgccaa
     1261 aatgacttcc atggtaacga tttcgattcc atctatcact tgctgccaga aactcattgg
     1321 aagatcaccc ccaaaatcat cacggcaaga atcggcccta acgaagcaat accgaccatt
     1381 ccaaaactgt cattttcatt tttcttttgt ttgatcatac tagtcatccc tccggcaagg
     1441 gccaagataa atggaacagt tactggacca gtagtcactc cccccgaatc aaaagcaatc
     1501 ggcataaatt cggaactggt gaaaaatgag gcgatcaaaa cgcctatgta gcctatagcc
     1561 atcaattgat aataggatag cttgaatacg acccgaagca gcgcaaaggc tagaaatact
     1621 ccagtgccga cgctgacgat cccaatcagc aacactctgc caatctctcc gtcagatata
     1681 tcatatactt gttgtcccaa aacttgcacg gaaggttcag caatcgtgat cacgatcccg
     1741 atagcaaatc ccaaactgac caaaacggtc aaacttttct ttttgatcat atatttccct
     1801 actagatctc cgacttccat catagaataa tctgctccaa acaaaaagag cgtcattccg
     1861 atcatcatga ttgccgcacc aaccagaaat gaagcgaggt cttctccttc taacggtgca
     1921 aaaacaaacg ttaaaatgac aatcaggaca gtcatcggca atatagcagc aatcacttct
     1981 ttaaaatttt ttagcatgta tcctcctcct ttactcttta agtttacctt aaaatgaaag
     2041 agttttcgag cacaaactta aaacgttatc atttaatttt tctcaacata aaataacaca
     2101 cgtcccaaaa gtatcttttt acttggaaaa atgactttga aggaacgcgc ttattgtgtt
     2161 tttttatttt acagagccga tcattccttg aacgaattgc ttttgcaaaa caaaaaatac
     2221 gatggcagtt ggtaaagtag cgatgactaa tccagccatg atcattccat agtctggtgt
     2281 ataggaagca cccatagcag ataaaacaag cggaaccgtc cgtttatcag gagattgcaa
     2341 agctactaag ggccataaat aattgttcca gctactcatg aatgtgatga ttgcagccgc
     2401 ggcataggta tttttagccg tcggcatata cactctaaaa aaaatactta gttcttttag
     2461 accgtctaat cgagcggctt ctactagatc ttttggaaaa gatttaacat tttgtcgaaa
     2521 gaagaagatc aaaaaagcag tgctaacaga tggcaggatg acaaccaaga aactgttgat
     2581 tcccaaaacc gttccgttca attgtgaaaa cattcgatat aaagggatca tcaatgccgc
     2641 aaaaggaacc atcatcgata gcagtagaat attgaaaatt aggtcttttc gtttactttg
     2701 ataaatctca aatccatatc ctgccattga cgaaatcagc aatgcaaaca cagtggtcac
     2761 caaagcgatc atcgctgaat tccaaaggga acgagtaaaa ttcagctcat tggaaaacaa
     2821 attttgaaaa ttgatgatca agttactgcc aatctttatt tttcccgatg tgatatccac
     2881 gggtgtattc gtcattccca aaaccatcca gacaaaaggg aaaatggaaa taaatgatag
     2941 gatgcttaat gctgtatact ttaatactga cccaattgtc gaacgaagtt ctaatgcttg
     3001 ttttttgacg ttggggcgtt cgattgtttc tttttctacc atatttttca tcgactttct
     3061 cctcctactt tcgtttggat tatcgacaat atcacaataa aggaaacaat aacaaaggaa
     3121 actgctgccg catatccaaa attaggcgtg aatttataac tcaaattata gatgtattga
     3181 gatagggtgg tcgttgcatt tgctggtccc ccgccagtaa tattttgtac ttcatcaaaa
     3241 agctgcaatg tcccgatcgt cgaagtaatg gaagtaaaca aaatgattgg ttttaaattt
     3301 gggatcgtca ctttgataaa ctgctgccat ttagaagcac cgtcaataga tgctgcttca
     3361 taaatctccg aatcaatatt ttgcatgcct gaaaggaaaa aaatcatatt gtatccagtc
     3421 caacgccaag tgatcgaaag aatgatcaga actctcgccc aaattggatg agtcaaccag
     3481 ccaatcggtg tgtcaatcat accaatgccc aacaacaagt tgtttacaag gccagattga
     3541 gaaaatagac ttttcatgat cagagaataa ctgaccatcg aagtgataca tggaagaaag
     3601 atagcggttc gaaacaaccc tttatatttc aactttttat catttaaaag gttggaaata
     3661 aaaagtgcta gaaacaacat gatcggtact tgtacaagta aatacaggaa tgtattaaaa
     3721 aaagcttttt taaaagttgc atctgtcaac atccgctgat aattacctaa cccgttaaat
     3781 gtcatattga cagggggacc actttgaaaa gacgtgatca aagccaaaac catcggaata
     3841 aaaaccatga ttgatatcaa aatgactggc aagattaaaa aagcatgccc gtttttgaat
     3901 aaatctttct gcttcattct tttccctcca attctatcat tgattatcta catgaaaaga
     3961 caagaaagac aatatctgta aggcagacgt gatctttttt gtcttttcgt ttgtctgatg
     4021 aaaaagcgaa gaaattcact tttttaccac cgatcaatta gccaattgtg cttctacttg
     4081 tttttgtgta tctgctagta ccttgtctgt ctcttctcca ttgatgattc gatgaagagc
     4141 ttcagctacg actgcttcaa ttgcataggt ctcatgtccg taattcactt ctggtatttc
     4201 agatgtccat gttgaaaaat cgtcaaagat cttttgacca ctgtaaaatt cagaagcttc
     4261 ttgataagct tcttgttcat tcgcgctaag catcgtagat actagtccga tttctttcgc
     4321 aagagtgccc atcagttctt cattcgaagc aaacgttgct tctaggaaat ctttcgctga
     4381 atcttctcca gctactcctt tgatcacata ccagccagcg ccgccaaggt tagaagcttg
     4441 cgctttttgc agattttctg gaagtgcagg tattggtgca atcttccatt ttccagattg
     4501 gttttctgct ccttggatcg ttgaagaata ccaagcgcca gttgggctag aagctactgc
     4561 tcctgattgt atcgcagtta ctccagcatt ccagtcagag gtttgttcga ctagatcttc
     4621 tttcaaaaga gtggcaaaca attcaagacc atactttaaa gatgcattgt cttggatcgt
     4681 gactgtctcc ccatcttcag atgtatacca ttctcctgcc tgttgcataa tcatccttac
     4741 tcgaccaagg tcagaaggat tgacttcagc gattttcttt cccgtctttt ctttgacatc
     4801 tcgcgctact tgaatatact cgtcccactt cagattctcc atatcctctt ctgtataacc
     4861 tgcttctgcc atcagatccg tacgatagaa gtttgctgtt acgcccgaat cgaaaggaac
     4921 accgtatatt ttatctccta ctttgtttac cgcaaattta tacggtgcaa aatgatcttc
     4981 ctttacaata gcagacaaat tagcgaatgc atctggataa gaagtcaaat agccttgtat
     5041 cctataatct tcaatcaaga cgatattggg caatccttct gtattcccgc tcgctaaagc
     5101 ggtgttcagt ttctgaacga tatcatcctg agacatcgta acaacttcta tctctgtttc
     5161 ttcgttctca taaacttttt ttgcttcatt cactgctttg atattgaatg tctcatccca
     5221 cgcccagaca gtgacttttt cttctttgtc tgctgtacta ctagcacttc cgcatcctgt
     5281 taagaaacct gatgctgccg ctaaacaaac gactccagca attaactttc tgatgttcat
     5341 ttttatccgc tccttttcca tccattagtt gtttacgttt gctacattca tcataccaaa
     5401 atttgaaaac ggtttcttta ttattcagat acttcaaaaa tttctcctaa aataataaaa
     5461 aaatacaaat caactatgac aaaaggaata atcttagcat ctagaccaaa gatcgaaatg
     5521 gtgaggtttc tttaaaataa aaatatcctt gcattttctc ctagaaataa gtatttttaa
     5581 attacaagac tattcttaag gcgggtaaaa aaatgccaat acgcgtaatt cttatcgatg
     5641 atgaacagac gattttagat ggaatgaaac agttgatcaa ttggtctgag cacgggtttc
     5701 aattaatagg gactttttcc agtccgctga aagcgcttga tttttctttg gtacatgcaa
     5761 tcgatatcgt ggtcacagat gtaatgatgc ctgaattaaa tggaatcgaa ttatcgcggc
     5821 tattaaaaca gcaacaacct gaaacacaga tccttatcct ctctagctat gatgaatttg
     5881 atatggttaa agattctttt aaagaaggcg tcgctgatta tcttttaaag cctcgattga
     5941 gtcctgattt ttttctaaat tccttaactg ccgtttcaca aaaaatcaaa aaaaagccca
     6001 acaaaagccc aatcaccaat cgttatgagc agatctgcga gaatctttca cagcagattg
     6061 ctggacaaac tcgtccattg cttgaccctc ttctttttga acacaccttg tttttctgtt
     6121 atataccgaa aaacggccat tcagttcaaa acaaggctct aaacaaaaac agtcgatcac
     6181 ccattcattg atggatagcg acgattcgtt tactatttat cctgtttcta ccttttcgga
     6241 agaatccggc tatgtaatca atactgattc caaagataca cttaggaagt ttgttcaaaa
     6301 gtttcgtcaa gaagtttttc caggtgattt ttttgttgtt tctgattctt ttgcaatcca
     6361 agatatcaat gaaatattcc aagagatcag aaattgcacc aaaggacaac gtttctatca
     6421 taagggaaag aaccttgctt atcagcatga acttcttccg ttattaacca accacgagca
     6481 gcaagcaagt agttatttaa caaaaatcgt tcataaagac tacgctttag ctgtcaaaga
     6541 acttgagaat ttcttcacga cgatattgga acagcctatt gatccagctt atttgaaaca
     6601 tgaggcaatc aatcgtttct atgcattact caacgctttg gctgacgagc atgttgggaa
     6661 tgaagaactt tctttgctca agatcgccct tccttcttta ttagccgatg ctgagtattt
     6721 cgaagatttt tctattcttg tcaaagaaac acttgagaaa ctcacccact tttctgcaaa
     6781 tgcaaaaaaa gacaatttcg atatcttgac tttgatctac gagttcgtcc aggaaaatta
     6841 tgagaaagaa atcaatttac aacttttatc cgaaaaatat catttttcat atagctatct
     6901 ctcagccatc tttactgaaa aatttggtat caacttttca aaatatctaa aaaaagtccg
     6961 tatcagtaaa gccaagctct ttttgacgga aacacggctt actttgacgg aaatctgtga
     7021 gaaagtcggc tataccgaac tgggttattt ctccagagtt tttaaagaag agacaggaat
     7081 gacaccttct caataccgta aaggaacttt tgtaaaatga gaaaaaaaat caaagagcat
     7141 gaactctttg ccaaacttct gttcattttg ttcatcggtc tttttctgca agccatcgtc
     7201 atttctttgt ttatttatca tcgatcaagg gatgcctata tccagctgtt caatcaatcg
     7261 aatgatgtgg tactaaaaaa gattcaatct gaatttgaaa gtttgaatga tacaatcgag
     7321 aatacattag ccgcttttga ttctaatcca gctgtcaaaa gctatttttc caatgatcca
     7381 gcccaacata tggaacagct tcagcaacta agaacaatcc aaaaaatgaa tgactctctt
     7441 tcaaaaatcc atccaatgat cgattacgat gtattgatct ttggagaaaa tggaagaact
     7501 tttgtcggaa acgacatgct cactgccgta tctgccgatt ctttttttca atctgcgatt
     7561 gctcagagag tgaatgaacg tgctgctgat acacaaatgc tttttgcaca ccacggattg
     7621 actcttcgcg ataagaaagc acccagcgtc ttctttgtca aaaaactgaa aaatacattg
     7681 aatcacgttt acggatatgc tgttttatcg atctcatcca agcaactagc gaatcttttt
     7741 caatctgtag taaatcctga gatatcgaag atctccttca tgaacgaaga acagacgatc
     7801 atcgcatcaa atgaagaaaa tacaattggg agccgatcaa tgattttcaa aaaactaaca
     7861 gtaggtgaaa caacgatttc aaatggacag cagttgaccc gtcttcctct gtaccgccag
     7921 gattgtacat tactcagtca agtcgatctt cattctttat ctaaccaaat gggcgtgatt
     7981 tttccgatta ttttgtataa tatcgtgaca cttgcttttg ctggctcatt ggtatttatg
     8041 tatttggatc gacacacaaa atcgatctac cgcttgattg attcgctaaa acggctagag
     8101 gaagatggct taaaagctac tgttcctgta caaggaagcc atgaagtcca attgctaggg
     8161 aatacgatca atcaattgct aagtaatgct cagcatcatt atgaacagac gatccaagac
     8221 gaaaagaaga aacgttcgct tgaaatccaa actatgcaag cacagataca gccccatttt
     8281 atttataata cgctgactag cttgaaattt ttgatttggc agaaaaaaac agatgaagca
     8341 gttcaaggaa tcgacagttt cattacttta ctaagaagta cgattgggaa aaaagaagaa
     8401 gtgattccag tcaaggaaga aatcaaaagc gtacaaagtt acatcgatct tttgagtatg
     8461 cgatatggcg aaagaatctc ggctaaaata atgattcctg atgaactgca gtcattatct
     8521 atgccgaata tgatccttca accaattatc gaaaacgcct atcttcatgc ttttcacaat
     8581 aaaacgcaag gattcatcac ggtgtacggc aaaacaaaaa atcagcttct tttattcgaa
     8641 gtgattgata acggcgatgg cttcgatact gaaaatacca aacaaaaaaa tgatcatttt
     8701 tcaggaatcg gcatcagcca tgtagatgag cggatacgcc taatgtatgg cgatgcatat
     8761 ggcttaacga tccaatcagt gattgggaca ggaacgactg taacgatttg tctaccgctt
     8821 cttcctaaaa atcaatcaga atatcaaaaa taaagaatag ccaagcgctg atttttttat
     8881 tttaagttaa ataaatcaat cagtattctt gactttcatc tacgcgtctc ttctactgtc
     8941 agcactggat aacagcccaa tatttgactt tctcctccga gcatcttgat ttcttggagc
     9001 gcattctcta ctaatgtcat tggacggtcc aacaacaaat cgatcacgaa aaaatattct
     9061 cccaagctag ttttcaatgg tcgggattca atcttactta agttgatttc ccgccagcca
     9121 aaagctgcca gcattttatg aagcatccct ggccgattag caggtagtgt caagatgaca
     9181 ctcattttta ctggagctga ctgctggctg gtcatctttc ggtcaccgac gatccaaaaa
     9241 cgtgtctggt tcaactcatt atcttggata ttctcagcta agatctccaa tccaacatgc
     9301 tgtgctgttt ctaatgaagc aatcgctgct gcgtcttctt tcggatgttc tgctacatac
     9361 attgctgcag cagttgttga ttctgttgct actaaaggaa cattaggata atgcgtttct
     9421 aaaaactgtt gtgattgtgc tagtgcttgt ggatgtgaaa ggatttttgt aatctttgtt
     9481 gctggattgc ctaaaagctg ctgcttgata ggaagaacga tttcactttt aacttcgact
     9541 tctggatgtt tggaaagaag atcgattgtg tgatgaacag ctccttccaa tgaattctct
     9601 acaggaacga cagccagatc gacttgtttg cgaaacaaag cgcgcaaaca aacagggatg
     9661 gaagcatacg cagtcaattg ttctgtagga aatagctgac aagccgcctg ataagtgaat
     9721 gaactttctg gccctagata gctgacgttc atatgctttt gatcctttct ataatggtat
     9781 cgatgatctt ttctggtgtt tgattggtcg tgttgattcg atgtgtcgca ctttcttcat
     9841 accaagaaag tcgttgtgcc aataatgctt ttatttcttc tcttgttttt ccaagagcta
     9901 aaggtcgaat agacgtttca tcttgttgga tacgatcaac tagacagtcc gcttctgcct
     9961 ctaagtaaag aacaatcggc tgtgttttta aaaaacgccg attttctgca ctttggacaa
    10021 tccctccacc agtcgcgata attttgtctt catttgacag ctttcttaaa atatctgact
    10081 ccacttttcg aaagcttttt tcaccgtaat agtgaaaata ttcggcaatc gacaattgga
    10141 tatgttcctc aatctttgta tctaaatcta catactcttt ttgtaaacat tgagctaacc
    10201 ctttaccgat tgttgttttt ccagcgccca tgaaaccaat cagcaaaatg ctagccatga
    10261 gcttctcctc ctgacacaag ttctgctaaa tcgtcaaaaa atgccggata agagattgaa
    10321 acagcttcag ctccttctag ttcgcaaggt ccatcagcta tcaaagcagc tacttgcagc
    10381 atcataccga ttcgatgatc gcctctgctg gacacttttg cgccatgcag aggtgtcggc
    10441 ccatggatga tcagaccgtc tgctgtcgct tttatctttg ctcccatttt ctgtaattct
    10501 tctgccaccg catcaattct gttggtttct tttactttta attcttctgc gtctttgatg
    10561 atcgtgattc cttctgcttg agtagccact aaagctagaa tgggcaattc atcaatcaga
    10621 cgcggaatga tttctccacc aatcgttgct ttcttcaaat gactcgtctt gacacttaaa
    10681 tcagccgatt ggttctgttc attgtgattc gtctgggtaa tcgctgcgcc catctcctcc
    10741 aacacatcta agataccagt tcttgttgga ttgaccccga cattttttaa caacagttgg
    10801 ctttccggaa caagaagtcc tgctgctaga aagaaagcag ctgatgaaat atcacctgga
    10861 acagttatct gttgaccagt taatttttgc ggtccggtca ctatgatcgt tttatcttcc
    10921 actgtgatcc ttccgccaaa ttgacgaatc atttcttccg tatggttacg ggaacgttct
    10981 ttttcaacga ttacggatgt gccttctgct tgtaatgccg caaacagcaa agcagatttg
    11041 acttgcgcac tggctacagg catattgtat cggataggtg ataaagagcg ggttcctgtc
    11101 acagtgattg gtagatactg gtcattttct tctccttgca agtcagcgcc catctcgcgt
    11161 aaaggttcca tcactcgccc cattggacgt ttagacaacg aagcatcccc gaacagagta
    11221 gtcgtaaaag gctgtccagc caaaataccc atcaataaac gtatggtcgt accggagttt
    11281 cccatgtcaa ttgattcggt tggttggaca aatgagtggc taccgcgacc atgaatcttg
    11341 atcacctctt cctcttcttc gatctcgaca cctaattgtt ggaaggcatg taaagtactc
    11401 agacaatctt ctgcgcgcaa aaaattttgt atagtcgtcg ttccttcagc aattgctcca
    11461 aacatgatgc tgcgatggga aattgattta tctgctggta tcctaacagt ccctcttaat
    11521 ccatgtattt gttgtaataa ttgcatttat ccagcctcct atttgatcca gcaatgataa
    11581 ctggtattag acataatgat tctttttgct tgtaacaaat cctgttggtt tttaaaactg
    11641 atttgcagta ttcctaaaat atcttccctg gtctcttgga tcttcaaatt aatcaaagaa
    11701 actcccgctt ttccgatcag tccagttact tctgcaataa cgccaggttc atctggcaca
    11761 tcgataaata aatcaaaaaa ggcaggaatc gcgccttgct tatggacagg caactggtct
    11821 cgactttctt ttgcccgatt gaaaaaagaa aagatttccg attggttctc agtcatgatc
    11881 cattctgcta tttgtgtcat ttcttgttgc caatctgcca atcgttccaa taatatctgc
    11941 ttattgctca acaaaatatc tgtccacatg acaggatctg aggaagcgat cctagtgata
    12001 tctcgaaagc ctcctgctgc cagttgtttg gctcgcggat actcttgatt gaattgttct
    12061 gcctgattga ctaagccagc tgccagaata tgtggaaaat gacttagcat tcctgttata
    12121 cggtcatgtt ctcttgctgt aagagttaca tattttgctt tggttccgca aaatagttct
    12181 tgcagttttt caacatcttt tttcgtcttt tccaaaggtg taaagatgta ataggcattt
    12241 tcaaatagtt tagcatctgc tgcctgtata cctgatttat gagaaccagc cattggatgt
    12301 ccaccgacaa accgaagatt tttctgctca gcggatgtca cgacttgctg cttcgtactg
    12361 ctgacatccg taatgatgac gtgatcagac aagttgattc tttcaaggac atcaagataa
    12421 gctaaggttg tacggacggg aacggctaat aagataacgt ctgcttgttc tgcacctgtt
    12481 tcaaaatcac ttgcaacgta atcaacgatc tgctgttcta ctgcttgctc acgggttttt
    12541 gactgactat cccaaccaac tactatcagt tctggattgg tctgacgaat acaaagtgcc
    12601 atagaagcac caatcagtcc aagccccacg ataaaaacat gttgtgccat cttatttgcc
    12661 ccctttttag taatgtttca agtagtcacg gtactccttc actgcagctt tcaactcaac
    12721 aagcgaatca cttgggaatt ttgacaatag ctctgtcgct accacagtgg ctacaacatt
    12781 ttccgcaacg acgctagctg caggaactgc tgtactatcc gaacgttcta cacttgcttt
    12841 gtaaggttct tttgtatcga tatcaacact ttgaagtggc ttgtacaatg taggaatggg
    12901 tttcatgacc ccgcgaatga caagtggttc gccattggtc attccgcctt cgaagccgcc
    12961 tagattattg gtacgtcgga aatagcctct ttcttcttcc cataggatct catccatcac
    13021 ttctgagcct ggtaatgaac cagaagtgaa tccgacccca aattctacgc ctttaaaggc
    13081 attgatacta accacagctt gtgcgatttt ggcatctagc ttcgtgtccc attgtacgta
    13141 gcttcctaat ccagctggaa cgcctccaac gagcacttct acaattcctc cgatcgtatc
    13201 tccatttttc tttgtctgat cgatcaaatc ttttattctt tgctcaactg ctggatcaac
    13261 aactcgtact tctgacgctt cagaaatttc tttgatttct tgaatcgaga tatttccagg
    13321 tatttctgct tggattccac caagacaaat cacgtgtcct gctacgatga tgtcaagttc
    13381 ttccagaatt ttcttggcaa ttgcgccgat tgctacacgc atggtcgtct ctcttgcaga
    13441 ggaccgttca agcacattcc gaagatctcg atgatggtat ttcataccgc ctaccaaatc
    13501 cgcgtgtcct ggacgcggac gtgcaactcg ccgcagtgat tggtcttttt caggcacttc
    13561 tgctacagac atgacagttg tccaattttt ccaatcttta ttttctacca ctaaagtgac
    13621 aggtgaacca attgttttgc cgtgacggat gccagacgtg atccgaacac gatctttttc
    13681 gatcttcatc cttcctcctc tgccgtaacc agcttgtctg cgagcgagtt cgtgattgat
    13741 ttcttcttct gacagaggta atcctgctgg tagtccttca ataatggctg ttaattctgg
    13801 tccatgggat tctcccgcag tcatataacg catcttacag tcctcctaag taatctttga
    13861 atgtctctgt gggaacagga acgatttttg cttgcccaat cttttctagc aagatgatat
    13921 tcaattggct tcctcttgct ttcttatcat gggttatcgc gtggaataat tcatctggat
    13981 gacttagatc gtacgtaatc ggcagatgga atttttgaag tatcctttct aaagcagctg
    14041 tcgatccagt tggagacaag ccgatttttt ctgcatgaga agtgatggct accattccaa
    14101 tagctactcc ttctccatga ctgactaccc catatcctgc tgtattttca attgcatggc
    14161 caattgtatg accaaaattt aaaataagtc gatttccttg gtcaaagaca tcttcttcca
    14221 ctacttttcg tttgatttcc aacgtagcag taatgattgg aacagcatgt tccagaagat
    14281 ctttttcgtc tttcagctcg ttcagctgtt tccaaagcgt tgcatctgct atagctgctg
    14341 atttgatgat ttcagcgatt ccttctcgta aacgacgtac cggcaaagtt tttagaacct
    14401 caggatcaat caatacacca gctggctggc taaatgttcc gacaaggttt ttcgctttgt
    14461 ttgtattgac tgctgtcttc ccgccaatac tagaatctac ttgtgcaagt agcgtagtcg
    14521 gaatttgaac gaaatggatc ccacgcatga acgtcgaggc cacgaatgct gctagatcac
    14581 ccaccattcc tccaccaagt gcaagtatcc catcgctgcg ggtaaaatca ttatctgcta
    14641 aaaaatcgta taactcagct gcttgttcta aagatttact ggtctcaccc gccggtacga
    14701 ttgaaaggac tggttcaaaa ttagcttgtc tcaattggaa catgattttt tctgcatata
    14761 gtggagcaac gtttgtatca gtgatcacag ctactttttg aggtctccaa atcgtttgaa
    14821 gccatgatcc agcctgttct agtgcgcctt tttcaatatg aatatcgtat ttttggttat
    14881 caacatgtac agtaagcatt cgtttcactt ctttctttta aaaagctgga attaatcgag
    14941 tgtctgaatc ttttccattg cttctttcat gatcgcaact tctttcatca tgcgtgagta
    15001 agtcttttca ttcaacgatt ggggaccgtc tgaccaagca tttgcaggat caggatggat
    15061 ctctacgatc atgccatctg ctccgcttgc cacacccgca cgagccattg gtggtacaag
    15121 ttcccaaatt cctgtaccat gacttggatc aacaatcaca gggaaatgag ttaatttttt
    15181 catcaatggg acagcactta aatcaaacgt attacgtgtc gctgtttcgt aagtccgaat
    15241 cccacgttcg ataaaaatga caggagattt gtcttcgact gcaatgtatt ctgcagcatt
    15301 aagccattca ttgatcgtac cggaaattcc acgtttcaat ccaacaggtt tacctgtttt
    15361 accgacagca gatagcagtt taaaattttg catattacgt gcgccaatct gtaggatatc
    15421 gctgtactca gccaccatat cgatatgccc ttcatccatc acttcagtaa tcactttcat
    15481 tccaaattca tcagccgctt gacggatgta tttcaatcct tcttcttcta aaccttggaa
    15541 agcatatgga gaagtacgtg gtttgaaggc accacctcgc agaatttttg cgcccccggc
    15601 tttggccatt cgcgcacatt ctctgatttg gtctaatcct tcgatagaac aaggaccagc
    15661 catcgtcacg aaactgccgt caccaatttt tactccgtct acatccacga ctgtattgcc
    15721 aggatggaat tctcgagaag tcaatttgta tgtgtttaaa atacgcacag cattttctac
    15781 tccttcatag cgtgtaaatg ctccttcttg taaacttcgc gtatcacctt ttagtccaat
    15841 cactactcgt tctgttcctt gatcgattga gactttgaat ccttcttttt cgatatgatc
    15901 gacgactttt tttatttgtt cttccgttgc ttcttttttc ataattacta tcattgtttt
    15961 tcccgctttc ttttgtttac ttatctatct tggctgattt tctctacttt ttcaaggtgg
    16021 ttttacatta attcctacta aatgaccgtg tcctgttgtt ctcattttcg ctccttcttt
    16081 cctacttatg acccagataa tcaacaaaaa aagatgtccc tgtaggaaat tgcctctaca
    16141 gtgaacatct tcaacgagcc ttaaaaagcg ctgcaaaaat ataaaatagc cactatagat
    16201 gaatttctct acgtggctgt aagtcgtgtt taaaaatctt tagccatcat agatacaaac
    16261 ctggtttgtt tgtacccacg aagtcatgaa tacaaaccta tctaaaatag ctaaagtaat
    16321 acgtattcag ttttgtaagt tttctagatt tcataaaaaa tcgctccaaa ctgatgtaag
    16381 aattgtacct agtatagaca taaaaaaatc gactgtcaat catttttatg aaactttttt
    16441 taattttctg atagttaact ttgtttttca gaaaaataac aattggtttt attgaagaaa
    16501 atagtcatga acaaaagtat ctgagaactt ttttactctc ttgttcatga catatagaat
    16561 aaagcagctt tgtcttgtaa actccgtttt tcaaataata atctaaagat tgctactgaa
    16621 taataaagcc gatttcatgg tcctcttcgc tgctgattcg gtaaggtgac tcaacatccg
    16681 ctccccagct attgataccc ccgactcctc ttacttttgc aaaaatcgta agaaccgttc
    16741 gtctttctgg cggtagttct tctatatgtg ttgcctgttc cagttcttct gctttgaatg
    16801 gtaaagcgga aaaagcaaat ggcgtatcct gctgttcaaa tcgcaacgaa aaatcttctt
    16861 gatctttatc cgtattatcc aacgtttgat ttcttgttag ttctacccat ttcgtttcca
    16921 tatgcatgcc gcattcttgg ggaacaaggt atggggaaac ggggagtcct gccactttat
    16981 aaataccttc gacaccacca gccatccgat ccggatatgt ttcccctgat aggccttcat
    17041 actcaaaaaa ttttgctttc gttggcataa tgaaccttaa acccaatgcg ggtaattccg
    17101 gtaatccttt ttgtccataa taatgcatat tgacaagcat tttaccctct ccagcgattt
    17161 ggtaggaaat tgtcacttgg gtttttggta ctgtgttgat ttccagtgta aaaatgattt
    17221 caaccgtttc agcgtattca ttacttgaat attgattatt tactggagca atcggcaaat
    17281 cgatcttttt attgtccacc agtacttcta tttctttgac ttttggatac aatccggctc
    17341 ctaaccacat accggattta aatccaaatc cgctacctct gtcattatcg gtcgttgctc
    17401 gccaaaaaac tggaagtgtt tcccggtata gccattcttt tccgttttta ttgagcgatt
    17461 ccagtccgcc tcttgtataa gaaaaaatat aatgcgtatt ccccgatttg acacctaatg
    17521 tacagtcgcc gaagacgatt gcaacttttt ccgtatccat atgactttta tttactgtat
    17581 ttttcataat aatatcttac ctcctgcatg gcgggttttt cttgtccatc tgcaaaaacg
    17641 atcccattcc ctgagaattc atagtcactt ggtttatcgt caaagtcacc gccatagcgc
    17701 atcacttctc tgcctgtgat tggatcagtc acttggatcg cctgatcttt aaaatcccat
    17761 atatagcctc cttggtacat ttcataacga tcaagcaacg tcatgtaaga atccattcca
    17821 cctaacgaat tccccatgtc atgcatatat tcacataaga tgaacggttt ttccgcttta
    17881 ttttcaaggt agtcaatgat ctcttctggt ggcgcataca tgcagctttt tacatctgaa
    17941 atcgaatctt cgaatgctgg atttggaaaa ttcccttcat aatggacaag tcgatcgggg
    18001 tctacttttt tgaagtaatc gttcatttgt cgaatgtttt cttccgcata agattcattt
    18061 ccaagagacc aaaaaagaat acttggatgg ttttttaatg tttcgaaatt cgtttttgct
    18121 cgatcaagaa cagccgcctg ccactgaggt actgcacctg gtacgttgta agaaggctca
    18181 aatgcgccca ttttttgcca tgagccatgg gattcgaggt tcgtttccgc catcacatgg
    18241 attcctgctt ggtcgcataa ataataccaa gtgatctggt tggggtaatg agatgtccgt
    18301 acgccgttga tctttgcatt ttttatgata gccaaatctt tttccatatc ttctatagtg
    18361 atggcgcgtc cttttttcgg atgccactca tgtcgattta ccccgttgat aatcatccgt
    18421 tttccattga agtagatgat tttatctttg atttcgattt tacgaaaacc gaaggaatag
    18481 tcaatatact ccgttactct tttttcttcg tctatcgtct ccaattcaag cttatataaa
    18541 ttgggctgaa aatgccccca cagtgccaca ttttcaaatc catcgatgcg aatcgtcatt
    18601 tgctctttta acggatattg ctgttgatag atttccttcc catcaggatc tagtatcgct
    18661 acattcagct gactgttttt ggctacttgc tcaaaagaca aatctacttc aagtttgcca
    18721 ttttgacatt tgtcatctaa gcgaggtttg atccaaagat cttctaaatg gttttgtcct
    18781 cgagcaacta agaagacatc tctgaagatc ccaaaaaatc ggaaaaagtc ctgatcttcc
    18841 aagaatgcag ctgtacttct tttgtaaacc tccacagcta gaatattttc ttcttccaaa
    18901 taaggtgtta aatcaaattc agacggagtg aacgaatctt cggcataccc gataaaatga
    18961 ccattcaacc aaataaacat tgcttgttct acaccagcaa aatgaatcga gatttgtttt
    19021 ccctttagac cttcttctaa tcgaaaagtc gtcaaatacg aaccaaccgg attgtcttta
    19081 gcagctgaaa agatcccttc cgcctctttc tcagggcttg tcgtgaaagg gggacggcga
    19141 aatacatgtc cctcccacgg atacatcgta ttgatgtaat ggatcttgtc ataatttgct
    19201 aattcaatat gactaggaac agtgatttca tcaaaagaac aggcatcaaa atctttttta
    19261 taaaatgttt ttggtcgtac cgaaggattt ggcgaataac aaaaacgcca tgatccattt
    19321 aaagactgtt taagggagga tgtggtttct acttcttccc ttgttgcata acaaacatga
    19381 tcgctatgtg catttgattg gttcactcta aaaacttgtg gatcatctaa ccattttata
    19441 tttgctttca tacttttttc cttctctctc ataacttttt gaaatgaagc agttctgttt
    19501 ggaaatcacc ttgaaaatcg gggaagtaaa gtccaactgt catcaattcg gcccccgaaa
    19561 atatccgctt cgaggtctgt tcctgataaa gtgcctcatc atctaacccc atcagatata
    19621 cttcatggaa cgctggttga gctgaagcta gtatcctccc taaaaacaca atagcttcat
    19681 cttgtttagg agacacaaac atccatgcgg caatattttc ttcaaaagga ctcgccaaac
    19741 gataataatg gccatactgg atcaccggac gaatcgtttg ataggatata atttggtctt
    19801 ttacttgctt tttttcttca ggagacagct ttgtcaaatc cagttcataa ccaaaaacag
    19861 cgctcatagc tgtttctcct cttgttttca acgaagtaga tctgtcggtc tgatgatttg
    19921 gtacagctga tacatgagct gtgatggacg aaatcggata agcaaggctt gttccatatt
    19981 ggattttcat acgctccact gcatccgtgt tatcacttgt ccatgactgc ggcatataat
    20041 aaataaaccc ggcatcaaac cgtccacctc caccagaaca gccttcccat aagatttccg
    20101 gataatcagt tgtcaaatgt tcaagtagtt cataaagccc gagcatataa cgatgcgcta
    20161 cttctccttg tctctgtggg tcaagggtaa tcgaatagac atctgaaagc gaacggttca
    20221 tatcccattt gatgtagtca agaggaatcg tatctaaaat ctttctcatt tgtttctcaa
    20281 tcgtctgccg aacatctaac cttgtaaaat ccagtacatg ttgtgatctg gaagcagaag
    20341 gcattctacc tggctcctgc ataagaaaat caggatgtgt tcgatacagt tcagaatcaa
    20401 ccgagatcat ttcaggttca aaccataaac caaatttcaa tcctttgcta tgagcataat
    20461 ctgctatttc acgtaatcca tttgtcaact tgccttcata ctcgaaccag tctcctaatg
    20521 aagaattgtc cgcatctctt tttccaaacc agccatcatc taatacgaac atttcgatgc
    20581 ctagctcctt tgcttcatca atgatcgcct tgattttttc actattgaag tcaaagtaag
    20641 tggcttccca gttattgacc agaatcggcc gttcagcaaa ttgatgacga cctcttgcga
    20701 ttctttcacg tagcaactca tggtggatct gactcatttt gttcaatccc tgacttgagt
    20761 aagaaaggat catttcaggt gtttgaaaag actggcctgc attcaattcc cacgaaaaac
    20821 gatggctgtt gatcccaccg acgactctca attgattgat ctgatctttt tcaagttcga
    20881 aagaatggtt gccggaataa acaaattgaa gtccgatcgc ttctccagta ttttctgtcg
    20941 tatgatgatg aactaaagca ataaagttat tcatatggtg actgctcgtt cctcgacggc
    21001 tttcaaatac ttttgttcca gataaaacag attgccgtga aatctgtctt tcattgacat
    21061 gtgctcctgg caaagcaatg acttcatcaa atcgcctagt atgggcaaag tctagctgga
    21121 aactagccgc tttttctagt ttgattgttt ctccggtttc atttcttatc tttacagatc
    21181 gtgtgatcac tgctctatca gtaaatatgg tatagaacaa atcgaaataa atcgctgttt
    21241 ctctatcctt aagtgaaatc accaacgttt gtgcctctga cttgtccatc acataagttt
    21301 gaggcaagcc ttcgatctct ggcttcccat ctgtaatata atggctgtca tatctcagat
    21361 ccagtaagtc tgatccattc ttgcgctgaa tgatcgatgc gggcgttcga aagtccatgc
    21421 tgccatgaga agagtattct tgcggtagtg tatctttcga cagagaccgg tcaggattta
    21481 agggaacatt tcctgaaaat ccacgatctc ttcggggata atttttattg tctttgtact
    21541 gcttgactgg tttgccaaaa taaatatgcg ccaatacatt gctttcttct atctttatca
    21601 gataagaaag aaatgtattt cgtaaatgga agactcggct cttttcatca aataagatga
    21661 aatttttatc tgtttttcta tgcgtaatat ccatcatttc actcccaaca aaacggaaac
    21721 cgtttacttt tttttataat tcctgtatac tgtttactaa acaattttgt caataaaaat
    21781 tttttatttt tttgaggagt gtgtaaaaat ggttggaatt agagatgtcg cacgaaaggc
    21841 aaatgtctct cctgctacag tttcccgtgt gttgaataac gatcagacga tccatgtggc
    21901 tcagactact cggcaacgga tagtagaggc agctgctgcg ttggattatg acatcagtac
    21961 tcgtaaatat atcaaaaaga gaatgccttc gattggtgtg atctctacga tcggcaaagc
    22021 gagcgaagaa caggatatct attacaaaca tttgcgagta gggatggaag aagaagctcg
    22081 acgtctgcat ttagggatga atcgaatcta taatctatct gataatccta aacaatggga
    22141 agatctagat cagttaggtg cggtgatcgt tgttgggact gttacgaaag aatcgattac
    22201 cgccttgtta aaacaaaaca tgcaaatagt cgtcgtggat aaccctgaca tccagcaaga
    22261 ggtcgatatg gtgtatgcag atcttgaacg gatgactaaa accgtactgg aattgttctt
    22321 agaaaatggt cataaaagaa tagcctatat cgggggatat aaagtcgata tggatgaatt
    22381 cggtgggaag cagatttcta taaatgaaaa gaggatgcgt gcctatcagc attttatgat
    22441 cgatcatcac ttagaaaaat atatgtctta tcatctaggt ggctggacag aaaaacaagg
    22501 tgaggtactt gcgactaatc tattagaaaa tgaatcccct cttcctactg ccattcttgt
    22561 cgggagcgat ccaatggcaa ttggtgtcta tcgggcattg aaacaaaaaa atatccaaat
    22621 tggagaagag attgttgtag caagctttga taatatcgag acaatcgcaa acctctcccc
    22681 tggcttgacc agtgttcaaa tcaatgcgaa atcaattggg caagcagctg ttcgaatggc
    22741 attggagcga attgacggta tacgggacga accaatcatt ttgacttatc ctgcacgatt
    22801 gattgttagg gaaagtttta tcccaagaac aaaaaggtat tgaaagagag gttgtgaaaa
    22861 gccgcttcgt ttcttcatac tcaaaacgaa acggcttttt cacaacctct tacttatact
    22921 tattcacaaa atccaatgtc tgctggtaac aattttgcga ttcttttagc gtgtaatcaa
    22981 attggtattc atgggtaatc tctttttttg tatctgtata aaacaaggat tgcacgggta
    23041 cctttaattc tgtcaaccga ttttctaatg cttgaccttg ctcctggaat gagtatgcat
    23101 ttccgtcagt tatatacgtt ggcggaaatt ccttagaaac atggtcagcc acactagctt
    23161 ctttcaattg ctcactcgtt ttccaatctt ttgttccaat caacgaccac gcaacggttt
    23221 tgacgaaaaa cttcataaat cgatcatccg aatgctgctg tgctgttagc ttcaaatcaa
    23281 caggtccgca ataagaaatg gttcctttca gactatcttt tggaagtagc tgtttgattt
    23341 tcatttgttt agcatacgca tcattcgttt gtatagctgc atattgcaat gcgatttgtg
    23401 aacctgcact atctccacca aaaaataatt gttccatgtc tagcaatttg tcgtcttttt
    23461 cttcagctaa taaatctttg atcagttcat tcacttgaag aacttgatta gggtattctg
    23521 aatcaggcgc taattcataa ttcatcgcaa ccactgcgat gttggcgtct gaaactaatt
    23581 ttgtcgcaaa ttctttgaca cccgatttat ctccgccgac gaatcctcca ccatgtaccc
    23641 aaaatagaac aggaacaggc cccttgctgt tttttggata gtagatgtca taagtattct
    23701 ctttatactt ggactcatac gtcaaatctg tttttttcgc cacgtttttt tctgcttgat
    23761 cgaacgtttt tttatcagtg atttgaacag tatttgaaaa catatggttg atcaagaatg
    23821 ctccaggtct gggggaaagc tggaaggcaa gaaagattgc aaacgcgatc ccaagaatga
    23881 ttccgaagaa ccatccgata aatttaagaa ttttcttttt cataaggctc cctcagtagt
    23941 tagtattaag cattctgatt ataccatagt gttatttcct atcaagctct cctagatgat
    24001 ttaatgattt tccccaaact tcttctgcaa tgcttttgac aaaagaaatt ttttccattg
    24061 ttcttcaaac aaaacatttt cttcttctgt tgaagcaaat ccacattgag gacttaagca
    24121 caaacgatcc aaaggcagat atcgtgtcgc ttcgtagatc cggtcaatca cttgctggtg
    24181 ctcttccatt tcgccatttt tcgttacagt caaaatctaa gacaactaat ttatcttcag
    24241 agactttctc taaaagaaca aaactcccag cacgttcact atcgtattct aaataatagg
    24301 cacggacatt ttcttgagta aaataatggg tctgctacgt cgtcatcccc cctgatgccg
    24361 ccaaaatcga ataataattt ccgcgtcaaa catgtatatt tagtgttgaa tcatttgaga
    24421 atatgaaaat aaaaatcttt ttgatcaatc agttaatcaa attgaaataa cgaaaaatct
    24481 gagacagaat gacgttcatt ctgacccaga tttgattttg cacaactcaa cagtccttat
    24541 tggcaaatcg ccaaaataat gtagactaac
//
LOCUS       DAFKHN010000038        24519 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFKHN010000038 DAFKHN010000000
VERSION     DAFKHN010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.038"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            8..81
                     /locus_tag="LY912_001543"
     tRNA            8..81
                     /locus_tag="LY912_001543"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="LY912_001544"
     tRNA            101..173
                     /locus_tag="LY912_001544"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="LY912_001545"
     tRNA            201..274
                     /locus_tag="LY912_001545"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="LY912_001546"
     tRNA            288..361
                     /locus_tag="LY912_001546"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="LY912_001547"
     tRNA            385..474
                     /locus_tag="LY912_001547"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="LY912_001548"
     tRNA            487..560
                     /locus_tag="LY912_001548"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="LY912_001549"
     tRNA            579..654
                     /locus_tag="LY912_001549"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="LY912_001550"
     tRNA            656..726
                     /locus_tag="LY912_001550"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="LY912_001551"
     tRNA            740..813
                     /locus_tag="LY912_001551"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="LY912_001552"
     tRNA            838..925
                     /locus_tag="LY912_001552"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="LY912_001553"
     tRNA            947..1018
                     /locus_tag="LY912_001553"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="LY912_001554"
     tRNA            1041..1130
                     /locus_tag="LY912_001554"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="LY912_001555"
     tRNA            1143..1216
                     /locus_tag="LY912_001555"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="LY912_001556"
     tRNA            1235..1307
                     /locus_tag="LY912_001556"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="LY912_001557"
     tRNA            1311..1383
                     /locus_tag="LY912_001557"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="LY912_001558"
     tRNA            1388..1458
                     /locus_tag="LY912_001558"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="LY912_001559"
     tRNA            1471..1544
                     /locus_tag="LY912_001559"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="LY912_001560"
     tRNA            1556..1627
                     /locus_tag="LY912_001560"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /locus_tag="LY912_001561"
     CDS             1893..3086
                     /locus_tag="LY912_001561"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBM6955247.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="LY912_001562"
     CDS             3216..4688
                     /locus_tag="LY912_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6955248.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="LY912_001563"
     CDS             4771..5559
                     /locus_tag="LY912_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBM6955249.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="LY912_001564"
     CDS             complement(5626..6294)
                     /locus_tag="LY912_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBM6955250.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="LY912_001565"
     CDS             6409..8121
                     /locus_tag="LY912_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955251.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9893
                     /locus_tag="LY912_001566"
     CDS             8124..9893
                     /locus_tag="LY912_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955252.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10098..10664)
                     /locus_tag="LY912_001567"
     CDS             complement(10098..10664)
                     /locus_tag="LY912_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBM6955253.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(10664..11620)
                     /locus_tag="LY912_001568"
     CDS             complement(10664..11620)
                     /locus_tag="LY912_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBM6955254.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(11620..12276)
                     /locus_tag="LY912_001569"
     CDS             complement(11620..12276)
                     /locus_tag="LY912_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBM6955255.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            12646..14664
                     /locus_tag="LY912_001570"
     CDS             12646..14664
                     /locus_tag="LY912_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBM6955256.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    14734..14940
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15091..17505
                     /locus_tag="LY912_001571"
     CDS             15091..17505
                     /locus_tag="LY912_001571"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBM6955257.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            17853..19406
                     /locus_tag="LY912_001572"
     CDS             17853..19406
                     /locus_tag="LY912_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBM6955258.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(19787..21571)
                     /locus_tag="LY912_001573"
     CDS             complement(19787..21571)
                     /locus_tag="LY912_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955259.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(21586..23307)
                     /locus_tag="LY912_001574"
     CDS             complement(21586..23307)
                     /locus_tag="LY912_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955260.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            23407..24168
                     /locus_tag="LY912_001575"
     CDS             23407..24168
                     /locus_tag="LY912_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBM6955261.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         7633 a         4477 c         5182 g         7227 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa taaagaggtt
     9901 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag cttctcatgt
     9961 ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt gaataaagag
    10021 gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac atatcattta
    10081 tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg cggctggttc
    10141 ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag tttggaacaa
    10201 aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta gacgacaagg
    10261 atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt gcgtgtagtc
    10321 tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt gaaaatccct
    10381 gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc ttgtagaaac
    10441 aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc atcgattgct
    10501 tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc tgctagaaaa
    10561 accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg ttgcaagatt
    10621 tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg ctcacctttt
    10681 tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca tcaattgcat
    10741 tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc cacggcgcat
    10801 cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg tcgcaaatga
    10861 cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag tcccgcaaca
    10921 ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata tctgaatcta
    10981 aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt aatccgttga
    11041 tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca tctaaataag
    11101 tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt gtttgcaatc
    11161 caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca actacttcat
    11221 ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt aaattgacta
    11281 cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta aaattttgga
    11341 aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg atttctttct
    11401 ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa ccagatacac
    11461 tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag tcaaatcctc
    11521 catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg taattccaag
    11581 aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct tctttctgta
    11641 agagttatct atttgttttc ttttttctct atacactgga taagtcaggc acagccaaga
    11701 aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca gataaatgcg
    11761 gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg tgcgtaaggt
    11821 tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa tcatactgcc
    11881 tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg ccaatgaagg
    11941 acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa ttacaataaa
    12001 tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc ataaagccgc
    12061 acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa agagttggta
    12121 gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat cgaaaccaga
    12181 aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga caagaaagaa
    12241 gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt gaagcaatga
    12301 cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac caatgtatga
    12361 ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga aagacatttt
    12421 ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa tccttttaaa
    12481 caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt acggtaaatt
    12541 acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat attaagagaa
    12601 gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga aaacattgca
    12661 agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa acgaggggca
    12721 gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt acagccggtt
    12781 cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac agcggcattt
    12841 atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct atatgcatca
    12901 gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt atctcaagca
    12961 ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt ctacatggat
    13021 acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg acaatatcct
    13081 tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc atttggcaac
    13141 ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga tgcgacagct
    13201 tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa taatatcatc
    13261 gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg cggtggagcg
    13321 actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag caattctggt
    13381 aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg tgattctgtt
    13441 tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg gaacaacatc
    13501 caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca ggaaaatggc
    13561 tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg tacatcaaac
    13621 ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt ttggaagatc
    13681 tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat caagaacaat
    13741 ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa tgctggagca
    13801 aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc aagttcttct
    13861 aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg gagcgtctca
    13921 aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca aaataacttt
    13981 atctacccag gacaacaact gactgtttca aacagtggat caacaaacag cacgtcaggt
    14041 aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg cagcagttcg
    14101 tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc aaataaaaac
    14161 ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt catttatcca
    14221 ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg ttcaactact
    14281 tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc atccactggt
    14341 aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa caaacatcat
    14401 atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat ctatccagga
    14461 cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc agttactggt
    14521 tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga cagtcatgga
    14581 attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat ttatccaggt
    14641 caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt gaattccaca
    14701 aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg aagtagtaaa
    14761 aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc ttttgaactc
    14821 gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg gccgttacaa
    14881 cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta cgtcctataa
    14941 aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag aaaacaaagc
    15001 aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat aatagaaaca
    15061 agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga aattgagaaa
    15121 aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga tcctgaaaag
    15181 ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct acatgtaggg
    15241 catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag tcaaggatac
    15301 aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca atatgcgcta
    15361 gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt ccgacgccaa
    15421 atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac tgatccggag
    15481 tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct agcttatgaa
    15541 gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa tgaagaagtg
    15601 atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat gcgccaatgg
    15661 atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt agttgattgg
    15721 ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg agcaaatatt
    15781 gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg accagatact
    15841 ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag agaaattacg
    15901 acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa aaaatcagat
    15961 ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc ttatgcaatc
    16021 aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt atcttcatac
    16081 ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga attcgctcaa
    16141 actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa agctgcttac
    16201 acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa acaagaagca
    16261 atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga agtcagctat
    16321 cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat cccaatcatc
    16381 cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt acggttgcct
    16441 aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa tatcgaggag
    16501 tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac gaatacaatg
    16561 ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca taacaaaaaa
    16621 gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta cattggtgga
    16681 gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt cttatacgat
    16741 atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg aatgatctta
    16801 ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc tgatgatgtg
    16861 gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg gccattagat
    16921 gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt ggatcgtgta
    16981 tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac attgaatgat
    17041 ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga ctatgaaaat
    17101 cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc ctataaagtg
    17161 gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc gattgctcct
    17221 cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc ttacgcacca
    17281 tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt tttccaagta
    17341 aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga tgagctagaa
    17401 aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac agtcagaaaa
    17461 gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc tctttgtcaa
    17521 taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca ttctgtctca
    17581 gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga ttttcatgtt
    17641 ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct ctgtaatcat
    17701 caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga aattgagagt
    17761 acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga ttttgacgca
    17821 taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt attatcgaag
    17881 tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa agaataatgt
    17941 tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct gtatcgttcc
    18001 tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa ttaaataatt
    18061 tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt gtttttcttc
    18121 tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg cttagtcaaa
    18181 gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat ctttattttg
    18241 agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag ttattgctga
    18301 gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc ggaatgaaca
    18361 cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag tcttcgcctg
    18421 gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc attcttttag
    18481 ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat ataaatgctg
    18541 cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca aatgaagggt
    18601 tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat gatctcaaac
    18661 ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat tgggtatttg
    18721 tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg gggctgattc
    18781 ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca tggtttatct
    18841 attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa acatggcaaa
    18901 cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta ttttatggca
    18961 acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact ttgtacattt
    19021 acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg atcaatcagc
    19081 cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca cgtgaaagtt
    19141 tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg attccggaaa
    19201 actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact caaataagcg
    19261 cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat gcagggaaaa
    19321 tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc gttcagcaac
    19381 tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg ttcagcaccg
    19441 agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt gtaactcgtg
    19501 attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc gtattttaca
    19561 agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt aaaaagggat
    19621 tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc caaaaagtat
    19681 cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa aagctatcga
    19741 tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac gctatctgaa
    19801 attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca gaatgtgttc
    19861 ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt tcaatcgttg
    19921 acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc attgcttgct
    19981 gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa ataacgacag
    20041 gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct tgagataacg
    20101 tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga ataaagtgat
    20161 cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc attttcccgt
    20221 aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa accatcccaa
    20281 aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg aattcgatct
    20341 ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt tttcctgcac
    20401 cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg acttgattca
    20461 tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt tttcctttcg
    20521 gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca tctaatatct
    20581 caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca taagaagcgg
    20641 tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag aagccgatcg
    20701 tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg aaggcgagtt
    20761 gattaatgaa acgaatggcc ggatagatag caaagttcat aaattgagca cgtttaaaag
    20821 cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct tgctgattga
    20881 atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt aaaacaccca
    20941 gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta gttgtaacaa
    21001 ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg atataaaaca
    21061 gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg atacctgtca
    21121 ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg tcacctactt
    21181 gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt tcttttcgca
    21241 ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata aatgaagtga
    21301 tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat gcttgtttga
    21361 tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag agatcatcga
    21421 tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat aaactgcata
    21481 gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa cgtatcaaag
    21541 cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata ttccttgtga
    21601 ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag taccttgtcc
    21661 aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg tactgaggcg
    21721 ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg ctcttaatgc
    21781 tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga tctctgctgg
    21841 tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat aattagaacc
    21901 gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt cttctaattg
    21961 agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc ccatctgcaa
    22021 gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac tgatgtggga
    22081 gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta cttttcctat
    22141 cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag atccggtccc
    22201 gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt ctagaactgg
    22261 atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat ttgtctgatc
    22321 aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct ctgcttgcag
    22381 tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca ataccatagc
    22441 tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag tcacgacacc
    22501 gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag aagcataaac
    22561 gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt tcactttgat
    22621 catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat atgattgatt
    22681 atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga tggtgatccg
    22741 atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca gtcgataaac
    22801 aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata gagaataacg
    22861 aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca tttggcaaaa
    22921 taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca aaagagatcc
    22981 agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga aatatttctc
    23041 ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag aggcaactgc
    23101 agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt ttataactga
    23161 ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg gtacacctaa
    23221 tgtaccggcg atttgtaaac agatcatcac aaaggtaagg agagcgagtc ctttgttttt
    23281 ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat acttttcgat
    23341 tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa aaagaggtga
    23401 gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga tttgccaaaa
    23461 tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca agaagagaat
    23521 gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt tttttataga
    23581 aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt gacggagtta
    23641 tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt gatgaaacaa
    23701 aaacaaaaag agataaggga gcgaaaaaaa cagttgaaat tgatgatcga tacaaacgag
    23761 gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga gtttgaagat
    23821 attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat gagtatgcca
    23881 gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt acatttattt
    23941 actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt cttattgaaa
    24001 tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag aatgtatgaa
    24061 aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac ggatgaaaac
    24121 aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga aatatgtgtt
    24181 taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct ggttcgatta
    24241 cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt tttagaggaa
    24301 atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg taattgtcct
    24361 cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat ggtgaactga
    24421 gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat gagaatgata
    24481 aattaaatag gtgcataaaa gcattacact taaaataca
//
LOCUS       DAFKHN010000039        24271 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFKHN010000039 DAFKHN010000000
VERSION     DAFKHN010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.039"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..572
                     /locus_tag="LY912_001576"
     CDS             <1..572
                     /locus_tag="LY912_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBM6955262.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="LY912_001577"
     CDS             576..1217
                     /locus_tag="LY912_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955263.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="LY912_001578"
     CDS             1214..2131
                     /locus_tag="LY912_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBM6955264.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="LY912_001579"
     CDS             2128..2799
                     /locus_tag="LY912_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955265.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="LY912_001580"
     CDS             complement(3340..3828)
                     /locus_tag="LY912_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBM6955266.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="LY912_001581"
     CDS             complement(4029..4295)
                     /locus_tag="LY912_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBM6955267.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="LY912_001582"
     CDS             complement(4295..4558)
                     /locus_tag="LY912_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBM6955268.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="LY912_001583"
     CDS             5034..5219
                     /locus_tag="LY912_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBM6955269.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="LY912_001584"
     CDS             complement(5361..7184)
                     /locus_tag="LY912_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBM6955270.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7781..10486)
                     /locus_tag="LY912_001585"
     CDS             complement(7781..10486)
                     /locus_tag="LY912_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBM6955271.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10792..11739)
                     /locus_tag="LY912_001586"
     CDS             complement(10792..11739)
                     /locus_tag="LY912_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBM6955272.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11929..12198
                     /gene="rpsN"
                     /locus_tag="LY912_001587"
     CDS             11929..12198
                     /gene="rpsN"
                     /locus_tag="LY912_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBM6955273.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12374..12736)
                     /locus_tag="LY912_001588"
     CDS             complement(12374..12736)
                     /locus_tag="LY912_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBM6955274.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12747..13868)
                     /locus_tag="LY912_001589"
     CDS             complement(12747..13868)
                     /locus_tag="LY912_001589"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBM6955275.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13884..14234)
                     /locus_tag="LY912_001590"
     CDS             complement(13884..14234)
                     /locus_tag="LY912_001590"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBM6955276.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14364..15875)
                     /locus_tag="LY912_001591"
     CDS             complement(14364..15875)
                     /locus_tag="LY912_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBM6955277.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16197..17549)
                     /locus_tag="LY912_001592"
     CDS             complement(16197..17549)
                     /locus_tag="LY912_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBM6955278.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17702..18778)
                     /locus_tag="LY912_001593"
     CDS             complement(17702..18778)
                     /locus_tag="LY912_001593"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBM6955279.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18974..20719
                     /locus_tag="LY912_001594"
     CDS             18974..20719
                     /locus_tag="LY912_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBM6955280.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(20999..21436)
                     /locus_tag="LY912_001595"
     CDS             complement(20999..21436)
                     /locus_tag="LY912_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBM6955281.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21420..22793)
                     /locus_tag="LY912_001596"
     CDS             complement(21420..22793)
                     /locus_tag="LY912_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955282.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23115..23603)
                     /locus_tag="LY912_001597"
     CDS             complement(23115..23603)
                     /locus_tag="LY912_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955283.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23625..24227)
                     /locus_tag="LY912_001598"
     CDS             complement(23625..24227)
                     /locus_tag="LY912_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBM6955284.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6960 a         5166 c         4486 g         7659 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt tatgggcttt
     7381 ttctttgaat tctataataa aaggatagaa cttgacttag aaaatcaagt tctatccttt
     7441 ttgatatctt aacttttgga agagagatgt aaggctgctt tctacccatc attcttacta
     7501 ctcgaagcat agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa gcttgcatct
     7561 gcggtaataa gcccaaccaa attaaaaaca taagaagctg tttttatttg gtcgttctta
     7621 ttacttgatg cagagcagct tttttacaac ctcttggtac acggtgttca atcagctgac
     7681 cctcggtatt agctcaaaaa aacggcaaaa tatgaggaac tatttttcca tttttttctc
     7741 taatactcag gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa atatggctct
     7801 catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag attgccgttc
     7861 ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc gtagcatttg
     7921 gccaataaat tcctcctgca gattcccgta acaagtttac cgcatgagta aatggcaaga
     7981 acggattgat catttggaag aatttccctg agacttggat cggatagttc ccgcctccgc
     8041 cagagatcga cagtactaag atgataatag cgatcccttt accgacatta tcgaataatg
     8101 cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca aatgacacgc
     8161 tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat gtaacgatca
     8221 agctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat tgttctcgtt
     8281 tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca acacttgaaa
     8341 gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta gctgaaccgt
     8401 tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta aagaagtcac
     8461 tttcttttgt tgcgtctagt ttcaataatt tgatgacttc gcctagatcg acttcttgtt
     8521 cgccttttcg gatcgcgtct gctgcttttt ggataccagc tttgatattt ggccagtcat
     8581 tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ttctggcatt ttttcattta
     8641 ctgttgtcaa tgtaccggtg atttcatttt ttagtgctgg ccaatcattt tggataaaat
     8701 cagcggccaa tcctaatttt tgctgaatga tcggtaattc attgttgtat aggtctgccc
     8761 cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta ttggcatcat
     8821 ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt gccactgcat
     8881 tcgttacagt tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg tccgctttgc
     8941 tcagtgcgcc ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga gaagtgacag
     9001 tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta ttaacaacgg
     9061 catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga acagctgtgt
     9121 tcaaagcaga taggcggttt tgcagattgc ttagcaaggg ttttaattga tttagctgat
     9181 caataattgg ctgtaatttc gtatttccag cacttgtttg caatttagtc aggaactcga
     9241 ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg ttcaatacat
     9301 tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct gttcttacag
     9361 tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat gtaacatcta
     9421 cactgtttgt gatgcttggt atcgcatctt tcagctgaga ggcacctgat tttgtttggt
     9481 ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata tcttgtactt
     9541 gttggatgat cgtcaagcct tgttttgctt catcgattcc ttggttcatt gtctcttgga
     9601 tcgaagcaaa atcgccgtcg atctctgcta gttgcttacc ggcattttgg atctctggga
     9661 ttttttcttg caaatcaagg atgatttttg cttgatcttt caactcaggc attttgtcat
     9721 tcaatgcaac gactttttca cccatctcat ctactttagg gatgtaatcc acgaattcat
     9781 ttgctttatt cagtttttcc ttgatttcag gtagttgact ttgtaattcg aggacttgtt
     9841 ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata tctttaactt
     9901 tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat actttcaata
     9961 aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc gaacttgctc
    10021 ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta tattcgattt
    10081 ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa tcctttggca
    10141 agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt tcttttgaat
    10201 caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact tgctccccaa
    10261 tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca gcaattggca
    10321 gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac gcatatagcg
    10381 aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg aaaatccgtt
    10441 tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt ctcccccttc
    10501 ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat cggctttttt
    10561 caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc tcttacatat
    10621 tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg aaagataatt
    10681 ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca ttttttgtct
    10741 ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt cttatttttc
    10801 gaatgacagg atgattttcc cagcaggagg atgtccttca actagctgat gtgcttggat
    10861 gacatgctta agtgaagcag acagattcat tgaaataaaa acatgaaagg ctcctttttg
    10921 gtaggctttg attatgccag caaaggcttc tgcatctaga tattcctttc ttggaacaaa
    10981 cgattcataa aagccttcct ttttttgccg caaatctaga tctgggaggt catttaatgc
    11041 aacatacctg ccgcctggtt tcatgatctg gatgccggtt tctcctttga tacttccttt
    11101 cgtcgcatcg attacaaggt ctgcctgatc agcaaattgc agacctggat ttgttttatc
    11161 ataagcagca aatgctgaag ctcctaattt ttttaccttt tcctcatttt tactggatgc
    11221 actggttaag attcggattc ccttttcatg gagaagctgg atcagacttg acccgaccgc
    11281 acctgatgct cctagtatca ttacagtatc tgtcggctgg atttccgtca aatggttgat
    11341 tagattataa gccgtaattc ctggcgtgac cattccggct gcttcttccc aactcatttt
    11401 atctggaatt tttgctactt ttgctgatgg caacacgact tcttctccgt aagtcccgcc
    11461 gactgcatgg acagctactc gatcacctac atgaacagtt gtgacatctg aaccaatctc
    11521 tgtcacaata ccagcgccat cattacctgg tacataaggg aatttcaatg ttcgtatctc
    11581 tttcatttct cctaaacgca aggcaacatc ataaggattc acactgaatg cttttatttc
    11641 tacacgaaca tgtccagaac cgacttctct gggatgagca tcgatttctt caaaaacatc
    11701 ttgtgcttct ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct ccctttttct
    11761 ttaagtttac gtttatgcct ttattttgac aaaaaaaatg tcttttcgtt ttggcgcatg
    11821 attcaaaaca aaatagttgt cttttttcgc gtaacgtgtt aaattattta tctaaaagcg
    11881 taaagattac gatttacgct aataaaaaat aattggagga atttgttgat ggctaaaaaa
    11941 tcaaagattg ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc tgctttacgc
    12001 caggaattaa aagcgcaaaa agattacgaa ggcttgcgta aacttccttt agatgctcgt
    12061 ccagaacgat tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata catgcgtaaa
    12121 ttcgggatgt cccgtataaa attccgtgaa ttagcacata aaggtttgat tccaggagta
    12181 aaaaaagcca gctggtaatc caagtctggc tgtaatgtaa aggaggaggg cgcatggacc
    12241 actccttgga tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc tggtactaga
    12301 agcagacgta tcttttttta cgcacagctg gtcctttttt atatgtaaag gctgcatggt
    12361 tacttcgcta tatttattta gtaacaggag tcagtgcttc gatacccaca ctaattttca
    12421 atgctcggtc aacttctgcc ataatgggtc gatccaaatg gcagaccttt tctttcaatc
    12481 ttgatttatc gatcgttctg atctgctcca acaggataac ggagtctctt tctattcctg
    12541 ttccagtagc tttgatccca atgtgagtcg gaagcttagg tttagccatt tttgccgtta
    12601 tggccgcaac aatgatcgtc gggctaaaat ggttacctag attattttga ataaccaaaa
    12661 ctgggcgtgt tccgccttgc tccgatccca cgactggaga aagatcagca aaataaatat
    12721 ctcctctttt taccatagga tcctccttat tcttgatatt ctcttggtat ccgctgtcct
    12781 aatccgcaag ccacttcata gtggatcgta cctaattgat ctgctatatc ctgcatagtg
    12841 atttctttgt ctgcattttt gccgataagc gtcacttttg ttccgacagg aaattcttga
    12901 ggcaatcgga tcatcagttg atccatacat acacgcccaa tcgtttcaca gtagttccct
    12961 tctaccaata gagaaaaacc ctgcatcttt cgtggccagc catctgcata accgatcggt
    13021 atcgttccga tccactctgc ttcaggagtg atatatgttt ctccatagcc gattccttca
    13081 cctgctggga gttttttgac ttgaatcaat tcagaaacca gctcaagtgc tggctgcaat
    13141 ggataaactt ccggtagtgc gtgcccagag ggattaagtc cgtacattgc tactccataa
    13201 cgaatcatat tgccgattgt ttcatcatgc cataaagccg ttgcactatt gctgacatgt
    13261 acatatcgag gaagttcggg aagttttttc agcacttcta taaagcgttc tttttgcaga
    13321 ttccaatatg tatcatctgc ctgatctgct gtagaaaaat gggtaaataa accttcccat
    13381 tctaatacac gactttcttt gatgaatgca gctgcctctt ttacttcttc aggtgtacaa
    13441 aatccgatac gacccatccc agtgtctgct tttagatgaa tcgaaagagg cgtctctagc
    13501 ttacttttct ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc tgcagttact
    13561 gataaatcat gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt caagataagg
    13621 atgggctgag taaatccagc ttctctcaac tcgactcctt catctaaatt tgaaacacaa
    13681 aagcccgaag ctccacctgc aactgctgcc tcagctgttt caatagctcc atgaccgtat
    13741 ccgttcgctt ttactactgc aaacaattct tttccttgcg gaagtcttgc aacttcattt
    13801 gctacatttt cagttatagc ttttttatgt atcactgctt tcgttgggcg gtgccaagcg
    13861 acaaccatcg tttttccttc tttctagtct tccaaaataa tttgtgcaaa agctgtttca
    13921 tttgtatgag taatactgac ccatacattg ccttcatgag gtgaacgcgt cacaacaggc
    13981 tgaccatttt cattttttaa aatctcgaca tcttgaaagg taacttttcc gatcccagtt
    14041 ccccaagctt tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa ttctacttgg
    14101 cgatgaaaag gcaaggactg gaatagtttc atttcatcag aggtcaagat tcgtgcaatg
    14161 aattttggtt tttcttcgat cagccgagtg atcctaggaa gttcgactgc atcgatccca
    14221 attcctttta tcatatgctt ttctcttttc aataaattta gaacactctc attctaccaa
    14281 attataacca ttttgccaca aataagtcca caaataacaa aaatgaaagt ttctcttaaa
    14341 aaagagaaac tttcatttta tgtttaatcg ttatttgaac ggattacaaa tccgcgtttt
    14401 ttatcattgt gacgtttacc gccatctttt tggctgttat tatttttgct ataaccgcct
    14461 tttgatttgt ttccacgata attaccgccg tcacgacgat tacggttgtt tccgccacca
    14521 cgtttgccat ttttattgta tccttttttc tgcattggca atgggcgttc tggtgtgatc
    14581 ttcactggca ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag tgcaactaaa
    14641 tcttgtgcag aatattcttc taataattta tctgctgttt gcaggtattt atctagacca
    14701 ttttctgcaa gttttgtttc gatttgttca actgcagcac ctaattgacc tttgaatgct
    14761 tctttttcgg ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt ttcaatcaca
    14821 tgcaagtagt ccatttcatt tggtgtaacg aaagtcacag acataccgcc ttttccggca
    14881 cggcctgtac gtccgatacg gtgaacgtag ctttctggat cttgagggat atcatagttg
    14941 tacacatgag tgacacctga aatatctaat ccacgtgcag caacgtctgt cgctacaagg
    15001 atatctaaat gaccgctctt aaatgaacgc aatacgctca ttcgtttttg ttgagacaaa
    15061 tcgccatgga ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc caattcgtct
    15121 acacggcgtt ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac atcaaacaag
    15181 cgagtcatga tatcgaattt ttcgtattct tttgcgcgga catagtattg atcgatcaag
    15241 tcagctgtca tttctttcgc tttgatcttc acatgatgtg gatttttcat gaatttaacg
    15301 ccaatattct tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg tctttgatca
    15361 ggaacttgtg aaatgatttt ttcgatatct tccaagaagc ccatattcaa catttcatct
    15421 gcttcatcca aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg gttaatgtgg
    15481 tcaagcatac gtcctggtgt acccacaacg atatgtggac gatctttcaa gccacggatc
    15541 tgacggccaa tatctgctcc gccgtaaacg gcttgtacac gtactttttt gtcgcgccct
    15601 aaacgatata attcttcttg tgtttggata gctaattcac gtgttggtgc gataactaaa
    15661 ccttgtaatt cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc aaatgcagct
    15721 gttttccctg tacctgtctg tgcttgtcca ataacgtctt ttccagctaa tgctagtgga
    15781 atcgtttctg cttggatagg cgttgcttct tcaaaaccag cgcgttcgac tgatttcaac
    15841 aattctggtg ataattctag ttctttaaat ttcaaatgaa tcctcctata tggttgttaa
    15901 ctgaggatgt agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt attgtttctt
    15961 tttgacagtg gccacgcacg tttttatcca ttcttagccc ctgtggcacc accgaaaaat
    16021 cactttgcga agtttaggca ttagaaaagc caaacgggtc gcgttcagct ttatcattat
    16081 tatgacatct ggcttcaaca agttgtttct atggcaaaac cagtccaatt tctcttcatc
    16141 tttcggcaat aggttattct aacatagttt ttcgttttct gcaagtttac agatttttat
    16201 ttcatttgct gaagttgttc taccacttca aataagccca tgctgttgct gccttttagc
    16261 ataatactat ctgttgcttc aagattttgt ttgatagcat caatcaattt attcttttct
    16321 ttttcaaaat agaacacagg tagttggggg tatttttggt tcaattcttc ttttagtgca
    16381 tgcatttgtt ccccataaag gaaaatcatg gcgaatttct caggatcgat atgttcactc
    16441 atttgcgcat gcatatttaa agactctttc cctaattcca gcatatctgc taacacagcg
    16501 attctgcgtc cttttgttgg cagattttta aaagtatcta ataccagtcc catggctgtt
    16561 ggatttgcat tgtagacatc gctcaaaata gctgcaccat ttcctgccgt tagccattcg
    16621 gttctgtttt gagtgataga aacatgggcg agcccttggc gtatctcagg tatggacagt
    16681 ccaaagaagc gcccgatcgt atacgcaatc aaagcattcg ttacattata acttccaggc
    16741 agcgggatcg taaatgtttc tccttctact acaaaatcgg tttgtgcttt tccttttgct
    16801 gtcacttccg catgaacatc gccatttcca ataccgaatg ttgtgactgt ttgtactaat
    16861 gttgccgtta aaggtgtcag caacggttca tctgcgggca caacgagtaa tccgtctgat
    16921 acaagtccgt cagtgatttc cattttggct ttagcgattc cttctcgcga cccaagattt
    16981 tctatgtgtg cttcaccgat cattgtgatt gctgcagctt ttggttgagc cataagtgaa
    17041 agttccgtga tttcattggc gtgatccatg cccatttcca aaacgatctt ttctgtatct
    17101 tggggcatgt gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt tccttgcgtc
    17161 ttatatgttt tgtatttttc agacaagaca gacgcggtta gatctttcgt ggtggtttta
    17221 ccattgcttc ctgtaattgc aacgacttct gcgcctactt tttccaagta ataggttgcc
    17281 aattgctgca tggctttcaa aggatctgct acaggaataa ctggaaaatt ttttggagct
    17341 tgttcaacag gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc ttgctggata
    17401 aattcatgtc catctcgcgt accagcaaga ggaacgaata aacttccttc ggttatcttc
    17461 cggctgtcaa attcgacatt ggtaatcttt gtcagtgcag agcattcgct gcccacggct
    17521 tgtgcaattt cttgtattgt tagattcatt gagatctctc ctaaaaaagg ttgtgaaaaa
    17581 agcgtttggc ctaaacggcg ggttcgcatg actctcactt ccaagtaaat ttctctattc
    17641 gtatttagaa gctagaatga acgcggttac gcaatcactc cagcctcttc tttatttctc
    17701 tttattcatt tttttcaaaa aaagattgac gctgatggta tcgattcatt cctaactgga
    17761 tcagttcttc aatcaaatca ccgtatttca agcccatatt ttcccataag agtgggtaca
    17821 tactgaactc cgtaaatcct ggcatagagt ttaattcatt caggaataat tcatttttat
    17881 ttgtcaaaaa gaaatcgcac cggctcaatc cgcttccacc taacatcgtg taagctaact
    17941 tcgcgtactc ttgcgctttt tgataaactt cttctggcac ttcggctgga atctgcattt
    18001 cgattttatt attgatatat tttgcttcat aatcatagaa tgctacgtct tttacgactt
    18061 caccaggcaa agtcgtccga acgtcttcat ttcctaatac agcaacttcg atttcgcgcg
    18121 cttcaattcc ttgttcaacg attgctcgag aatcatactg ataggctgtt gctaaagcat
    18181 tttgcagctc ttctcggttt tctgcttttg taatgccgac actagaaccc atattcgccg
    18241 gtttgacaaa catcggataa agcaaagaac cttcacattg atcaaatact tttttaggat
    18301 tttctttcca ttgattctta agtactggta cataaggaac ttgcggcaca ccagcagctt
    18361 gtaaaatata cttggtcatg attttatcca tggcacatgc actggtcaat acgcctgcgc
    18421 cgacataagg catattcaat gtctctaaga agccttggat cgttccatct tccccgtttg
    18481 gcccatgtaa aactggaaaa acgatggctc cttcttcttt gatttcgccc ggattgatca
    18541 cttttcctgt aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga tgcaagacat
    18601 ctttgctggc aggtttttct gttagtaatg gacctttgac ccattgtcct tcttttgtaa
    18661 taaatacgag ttgaacttgg taataattat aataaatggc atttaaaact gaaaatgcgg
    18721 aaagaatgga cacttcatgc tctgcgctgc gtccgccata tagtaaagta atcttcaaaa
    18781 gattgtcctc ctgtattcta aatcgttcag tgatttactc tcatatttta gcacaaaaca
    18841 aaaataaacg aataacttat ttataaaaaa acgagccagc ttctaaaaga acgagcgtca
    18901 tttatttttt gtcagctaga ttatttgtcc cgttttttat aaaaagttat gataaagaaa
    18961 aggagggatg atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa tcattcgagt
    19021 gttcatcaat tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg aacaggtaaa
    19081 aaaagccttt gaagaactag gccccacctt catcaagata ggacagatgc tttctgttcg
    19141 agaagatttg ctttcttctg ccttcactca aacattcaaa acattacaag atagtgtacc
    19201 tagcgacaca ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc tttcattatc
    19261 agatatattc gatgattttt caaaatcgcc ttttgcctct gcttctatgg ggcaggctca
    19321 tcgtgccaag ctgaagaacg gtgacgcggt agtcgttaag atccaacacc ctaacatcgc
    19381 cgaagagatc cgacttgatc ttcaactatt tgaacgagcg atccctttga tcaaatacat
    19441 tcctgaaact agcgtagttg atctaaaagg ggtactccaa gaagtaaaac gttccttgat
    19501 caatgaaatg gacttcttaa aagaaagtca aaatggcgaa caattctatc aaaagaacaa
    19561 tggctggaaa gagatccgca gccccaagat ttatgacgct ttttgttcga aaaaagtgat
    19621 cgtgatggaa gaaatgtctg gtaaaaactt gaatcattta atgaacgccg aaaacaaaac
    19681 tgaaactttt atcactggaa ttcaaaacaa gcagctgaaa caagaagttg caaagctttt
    19741 agttgagaac tttatgaaac aggtgtttga tgatggtttt ttccatgctg atcctcatcc
    19801 agggaatctg ctattccatg tactaacaaa agaagaacag acacaagcta gccgaaaaac
    19861 tgaaacagtc catgaaaaag agttcggttc ctttgctttt cgagcctcca cttctgcaga
    19921 agaccctgtt gcgccatata ccatcaacta catcgatttt ggtatgatgg ggcatctttc
    19981 tgcaggactt aggcaaaaac tcacacaagc cgttttagcg ctgtatacga aagatgctta
    20041 tcgaatcgaa aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg atgaaagtcg
    20101 gttccaccaa gaactgacaa gttttcttga acagtattat gattctccta ttgatgaaat
    20161 caacttgcaa gaagtattca cacatgtcgt gacgatttgt catcaaaata atctgcagtt
    20221 cgatcgtgat atcacgcttt tgctgaaagc atttgggaca ttagaagggg tgatccgcgt
    20281 cctcgatcct gaagtttccc tcatggaagt cgcttcgcct tttgctcaac attattttct
    20341 cactcatctg gatgtagaag atacattgaa acaaagcgga ttagacttat tggaagggat
    20401 gaaggctgcg cctaagatcc ctcaacagct ccaccatcta ttagaaatgt ggacttcggg
    20461 acaaggaaaa gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca ggatcgaaag
    20521 tatgatcaat cggcttgttt tcggtatgat tttagctgca ttgatcgtag ggtcctccct
    20581 gcttgtccaa gcagcacctg tagaaaacgc agaggtcgtt tccttattag ggatatttac
    20641 gtatgctatt gccgcattcg tcattatttt tttggcaatc gatgcattga tccaaatgta
    20701 taagaagagg aaaaagtaga aaaaggttgt gacagaaaga atcagcttca agaaataaga
    20761 aggggtttta cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat ttttcgaaga
    20821 ggctacttct gaaacaccga gaataaaaaa tgtgaaaaag ctgttctgca cccagtaata
    20881 agaacaatca aaaagggaac atggaacaca tttatcctgt ttccctgttc cctttttgat
    20941 gtattcgagc ataaataaaa taccttcgtt acctactatc ttctgtactt ggtaaacctt
    21001 agtcaattgc cttttttaac gcttgacgaa aagacatatg atctttctcc gtaaagggtt
    21061 ttggaccctt tgtccttatg ccagcttttc ttaactttcc actatgataa cgttgttcta
    21121 gaagcgtgcc gatattcgct tcgtcaaatt cttttccaga gtgatggaac actcgcacac
    21181 ccttcggcaa tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag tcattcttct
    21241 taaccatacc gacgatttta taatccgcac tatcagctcc gcggtctacg tagacgattt
    21301 ggacatgatt agcgtattct ttggtcgtat aatggtccac actggtcacg ataaccacgt
    21361 caagaccata ggattctcct aattttatga catcttcttt tactggagaa ccatctccat
    21421 caatgaatag cctcattctt tttcgccttc ttccataaat gataaacagt tactaatccg
    21481 ctcagtaaaa gaccaacatt gatccatttt gccaagataa gcagttgtac actttctatc
    21541 ggcactgatt catggttcag cgtgatcaat aatagatgga ttggctctcc catttctttt
    21601 gctaaaacaa acaaaagcgt catcaataaa aactggtgga tcacactccc tttattttga
    21661 gtagtatact tgacaacgat ccggcgatcc attggaatag ctgtatcagt ttgataatat
    21721 tccttattta gccagctgcc tgttactacg tgccagaaac taagcagaaa gacacctatc
    21781 gcaaaaccat ttggaatcaa gaggaccaat aaagaagaac tcagtccaag caattgcata
    21841 gccaatggag accatgttaa acgtttcaaa atccatggtc cgactatttt tgctgcaatc
    21901 aagcctgctg cataaggcaa atacataaaa atcgaaagtt tttctaatcc gtacagtatg
    21961 ccaacataaa aactgctaaa taaaaaaagg aaattcccta gcattccatt tagaaaagta
    22021 aacagattta gccagcttgg caacttccat tccttcttct ggtgtcctaa aacaaacacg
    22081 aacaagatga acagcagcaa gaaaccataa atagcaagat caaaaagcct ttcatcgaat
    22141 aacaatcggg catttctcaa aagaaacaat aagccaaaga atatcaaaaa taaaacaagc
    22201 tctcgcgtag ctaccagatt tcttttgatg tctttgaaat ccagttcgta acgcggataa
    22261 tgactaaccg tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa gcttgctgca
    22321 atctgagtcg gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca gatagctgca
    22381 aataagtact ttttcccatc catattgata aaaccttgcg tcttttcgtg aaaattgacc
    22441 gtggtattag caggtacaag ccatgctgca ctcagcccta gcaaaacact tgaaaaataa
    22501 aataaaggaa aataaaatac gcctaatatt ccaagcaatg aaccagcacc accaatcagc
    22561 agagcgatca tcagcaacgt gtaactatct agaccaaatc gtagactgtt gactaaaaat
    22621 agtccagtca tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag ccaattatgc
    22681 gagtctgtta gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt acttaagata
    22741 aagggcgttg tttgtgtaaa attacgccca aatcgtttga gtttttcgaa catgacaatg
    22801 gctccttaaa cagtcttata actaatctgc tcttcgattt tagcattaaa ggggaaataa
    22861 accaatttta cagaatatat tcttgtaaaa aaaaatacag aaagaagcat aagcttcttt
    22921 ctgcattttt acggtacttg attactcaag cagacaagcc cttctccaca aaagtcttgc
    22981 ccgacacccc tgcatccggc aggtgataaa gatagaaatc aattatcctg tgcctccaaa
    23041 atcaattagg agctctgtaa accagagtcc ttctcgaccc gtcgcataaa tttactttaa
    23101 cacagttcct atgtttatgc gagagctttt ttcattttat aatcgaccat ttgaaatcct
    23161 tgaccgatat ctgaaataag ttcttctgta atctcaaatc cttcatgctt ataaacctcg
    23221 attgcttgat gattcccctg attcactcgc aaaaagatct ctctttcctt tgtttgcgca
    23281 gcaagttctt cataccagcg aaaaactgaa gaagtcaatc cttgaccacg tactttattt
    23341 agcaaatata atttacttaa ataaattttt ccatttatct cttcataagc agtgtaaccg
    23401 acagtctttt cttcgctttt taataaaaag taggacacac cttctgtcag ttctttttga
    23461 atctgttttt ttgactgata agttttcagc atgtaatcca cttgtttttg accaatgatc
    23521 ggcacaaaaa cttccggcca tacttcttgt atgactgcca tcagctcatc cagttcattt
    23581 tctgttactt ttattttttc catacaccca cgtccttttt tacattataa atgaccttgc
    23641 gcttgatgga ataaaaagag catgatcatg ctatacacac ccaccgacca cggtttcaag
    23701 aaaatcacaa tctgcataaa ttccctaaaa gataatttcg tcaaaccagc tactagacag
    23761 atcaagtcgt ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt tttaatatct
    23821 ttcgtttttc ttgtcagcaa ttcatcaaat ttctgatact tttttggcga taaaataagc
    23881 tggacaaagg ctacgccata gtaacggaca agcaaaaatc cgattgcttc cccaatcact
    23941 aggccaatac aactatataa aagcccaaat ccattgccaa acatcagcat gcccgctact
    24001 gaggagatcc ctcccggcaa aataggaatg atcacttgga tcacttgcaa cagaacaaat
    24061 atcatcactg catacttgcc aaattgctgg ataaacgctt gcaaagacgt gctcgatcga
    24121 aaaatcccat gatgataagc ataaagaatc aacacaaaga aaaaaaacag accaataatg
    24181 ggcatgatct gaagacattt ttgtaaaact gatccttttt tagacatcta tattccccac
    24241 atcttttttc atttattaaa actgcctcct t
//
LOCUS       DAFKHN010000040        23881 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFKHN010000040 DAFKHN010000000
VERSION     DAFKHN010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.040"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(56..790)
                     /locus_tag="LY912_001599"
     CDS             complement(56..790)
                     /locus_tag="LY912_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBM6955285.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1117..1527
                     /locus_tag="LY912_001600"
     CDS             1117..1527
                     /locus_tag="LY912_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBM6955286.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1520..2221
                     /locus_tag="LY912_001601"
     CDS             1520..2221
                     /locus_tag="LY912_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBM6955287.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2221..3807
                     /locus_tag="LY912_001602"
     CDS             2221..3807
                     /locus_tag="LY912_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955288.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3826..4047
                     /locus_tag="LY912_001603"
     CDS             3826..4047
                     /locus_tag="LY912_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBM6955289.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4044..4805
                     /locus_tag="LY912_001604"
     CDS             4044..4805
                     /locus_tag="LY912_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBM6955290.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5185..5694
                     /locus_tag="LY912_001605"
     CDS             5185..5694
                     /locus_tag="LY912_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBM6955291.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5769..6308)
                     /locus_tag="LY912_001606"
     CDS             complement(5769..6308)
                     /locus_tag="LY912_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBM6955292.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6448..7059)
                     /gene="rpsD"
                     /locus_tag="LY912_001607"
     CDS             complement(6448..7059)
                     /gene="rpsD"
                     /locus_tag="LY912_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBM6955293.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7321..8172
                     /locus_tag="LY912_001608"
     CDS             7321..8172
                     /locus_tag="LY912_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBM6955294.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8200..8835
                     /locus_tag="LY912_001609"
     CDS             8200..8835
                     /locus_tag="LY912_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBM6955295.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8855..9628
                     /locus_tag="LY912_001610"
     CDS             8855..9628
                     /locus_tag="LY912_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBM6955296.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10036..10833
                     /locus_tag="LY912_001611"
     CDS             10036..10833
                     /locus_tag="LY912_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBM6955297.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10811..11224
                     /locus_tag="LY912_001612"
     CDS             10811..11224
                     /locus_tag="LY912_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBM6955298.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11208..13853
                     /gene="mutS"
                     /locus_tag="LY912_001613"
     CDS             11208..13853
                     /gene="mutS"
                     /locus_tag="LY912_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBM6955299.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13871..15979
                     /gene="mutL"
                     /locus_tag="LY912_001614"
     CDS             13871..15979
                     /gene="mutL"
                     /locus_tag="LY912_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBM6955300.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16001..16561
                     /gene="maf"
                     /locus_tag="LY912_001615"
     CDS             16001..16561
                     /gene="maf"
                     /locus_tag="LY912_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBM6955301.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16646..18634)
                     /gene="treP"
                     /locus_tag="LY912_001616"
     CDS             complement(16646..18634)
                     /gene="treP"
                     /locus_tag="LY912_001616"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBM6955302.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18857..19570
                     /gene="treR"
                     /locus_tag="LY912_001617"
     CDS             18857..19570
                     /gene="treR"
                     /locus_tag="LY912_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBM6955303.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19647..20093
                     /gene="msrB"
                     /locus_tag="LY912_001618"
     CDS             19647..20093
                     /gene="msrB"
                     /locus_tag="LY912_001618"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBM6955304.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20263..20865
                     /gene="ruvA"
                     /locus_tag="LY912_001619"
     CDS             20263..20865
                     /gene="ruvA"
                     /locus_tag="LY912_001619"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBM6955305.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20878..21879
                     /gene="ruvB"
                     /locus_tag="LY912_001620"
     CDS             20878..21879
                     /gene="ruvB"
                     /locus_tag="LY912_001620"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBM6955306.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21908..22486
                     /locus_tag="LY912_001621"
     CDS             21908..22486
                     /locus_tag="LY912_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6955307.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22538..23020
                     /locus_tag="LY912_001622"
     CDS             22538..23020
                     /locus_tag="LY912_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBM6955308.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23137..23511
                     /locus_tag="LY912_001623"
     CDS             23137..23511
                     /locus_tag="LY912_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955309.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7801 a         4291 c         5120 g         6669 t
ORIGIN      
        1 aataaaaaaa cttggtacgc aatcgctgta ccaagttttt ttatttagct tttgattaag
       61 ccataaataa taatttatat aagaatactg ctacgacacc agcacagata ggtgctacaa
      121 ctggtaccca tgcatatccc cattgagaag aacctttatg tttcaatgga agaagtgcgt
      181 gtacaagacg tggagcaaag tcgcgggctg ggtttagtcc aggacctgta ggaccaccaa
      241 gtgaagcaac taatgtccat acaaggaaac caagtgctaa gtgagctgta ccaagattat
      301 cttggaagaa tggtgctttt gtaataccta gggcaccaaa gaataaaacg aatgaaccaa
      361 agaattcatt gacgaaacca ttgaatttag aaccaacgct gttgattgtt gagaatgtac
      421 ctaacacatg gtttacgtct tctgtttggt cgtagtaagg tttgtaacaa gctactacga
      481 tcaattgtcc aatcgctgca ccaatcaatt gtgcaatgat ataaggaaca acttcagccc
      541 aagggaatag accattagat gctaaagcaa ttgtaaatgc tgggttgatg tggttaccgc
      601 tgattccacc aaaaatcatt gctggcatca taaccccgaa tccatacccg acagcaatca
      661 gcatccagtc actgccatat ccttttgtac cttttaaatc tacgtttgct acagcaccgt
      721 tacctagaac gattagtaat gctgtaccaa tcatttccgc cgcaagacgg gtcattagtg
      781 agtaatccat aaatacctcc aaaagttata aaaatgcaaa aaaaaaagaa acatcaacac
      841 gaaaagcatc ggtgcagtgt ttcgtgtcgg aaggatttct gcagtcttaa caaatgtgaa
      901 taaaaaaatg aattccatta cttataagaa accagaccaa cagtaaaact ccaactcttt
      961 ttaaaagttc tccacaaatc accaagctta actataaata taccaaaaaa aaaacgtttt
     1021 ttttctcaaa aattgtatct tagaaacagc atgttttgaa actttcagaa aaggtttgtt
     1081 agtaaaatga aagctatacg taaggagtgt tgtttgatga aattttttca agagtttttc
     1141 attattattt tcttttctgt attaggagaa ggcatacgga tttttgctca tttacctatt
     1201 cctggaagta tcttaggtat tcttttttta tttttagcat ttgaaatgca tcttgttgat
     1261 cctgaaaaaa tcggagcaac tggtgatttt ttattgaata atctagccat tttatttgtt
     1321 cctgctggtg taggtttatt ggaatatttt gatgatattg cttcgatatg gcctgtttta
     1381 ctgggagcag tcgtcgtgtg ttccatcgtc acgatggttg cagcgggaaa aacggcagaa
     1441 ggtgtagaag ctttgctggg ctatgtccgt aagaaaaaag cagaaagggt atctgtaaac
     1501 gaaatggagg agaatcaaat tgactgagtt ttttgtgaat ccattatttg gcttaagttt
     1561 gactttagga gtgtacgtat tatctgacaa atttttgcgg aaatataaac tgcctgtttt
     1621 gaatcctctc gtattatcga ttgttgttat tatcttattt ttgcattttt ctgggatcag
     1681 ctataaagac tataatatcg ggggcaattt tttgactatg ctgattactc ctgcgacagt
     1741 ggcacttgcc atccctcttt ataaaaactt ccgtttactg aaagagaatt tttatcctgt
     1801 aatggctgcg attttagcag gaatagtcgc aaattgcttg gttagtgtag ggttcggtta
     1861 cttcttctct cttcataaag agatggtgat ctcattacta cctaaatctg taacgacggc
     1921 tatttctgtc gatttatctc atacgatggg cggggtgaat gccgtgacac ttgctattgt
     1981 tgtctctaca ggtatttttg gttcgctgat cgccactcat attttccgcc tattcaagat
     2041 cgaaagtcca gttgctcgcg gtgtggcgtt aggaagtact tctcatgcta ttggtacagc
     2101 aaaagcaatc gagattggtg aaatagaagg aatcatttcc ggacttgcga tatgcgtcaa
     2161 cggaatattg accgttttat tgctaccgtt attctttcag ccttttgctg gcttgttttg
     2221 atgcgaaaac cactatttta tgctacaata accaaaacgt tcgagcataa aaaaggaggg
     2281 aaagacgtgt atttgtcttc cgagtatctt aaacaatttg ataaagatct atattataag
     2341 attctcctcc tagaaagttt tgaggatcaa gcttggcata ccgctgcaca attagcgcaa
     2401 gttgttcagc tggatgcccg cagcgtgtcg aaatacctga acgagctgtc taaaaactat
     2461 cagcagttta gcggtaagac acaccctttg tttacaaaaa atcaccgttc tggttataac
     2521 ttttatgata cgctcgattc aattgaacat gagcgttttt tgatctatct cgtgcaaagt
     2581 acgctgaaat tccagttgct gcacgacatt ttttttgaag aattccatac aatgtaccaa
     2641 tttgcgcaaa agcattacat tagtgaatct actgctcatc gaaaaatcaa tgaatggaaa
     2701 cagcaactgc aaacttacgg aattcggctg caacgaggta catatatcgc tcaaggcgaa
     2761 gaagaaatca ttcgacttta cttgcatatg acattctggc agttgtttcg agggaaaatc
     2821 tggccatttg aaacgatttc tcaaatggac gtaaagaata tggcagaaca tatcatggct
     2881 ttttttaatg ttcgtctgaa cgagatcaaa aaaagacgat tggaatatat gctaggtgcc
     2941 ttttttttaa gaaaatcaca gaagcattat gttgtattga atgagaaaaa aagacggctg
     3001 atttctgaca atctgttgtt ccagcgattt tgccaggtca tggagccggt atttcctaat
     3061 tattttcaag tagaagacga gttaggcgca ttatttcttg tactgatgac tcgtgaagaa
     3121 tattatagtg atcctaagat acggaagaaa atttttgatt ttcatcaaca agcaaaaaca
     3181 ccgcccttta cagccctttc agaagcaaaa gccgctcttt ctctttatca ggaagagcag
     3241 gggctgccag cagaaaatct aaccttcgag gcagaaaact atttattcag cagtcatttt
     3301 ttcgcctatc tttttcctaa tgcgaaagaa acgattgatg gcaatagtag tgattttatt
     3361 aatcatttag ttattgaaaa caaggaattg aaacaatggc tcgtacattt ttttgaaagt
     3421 agacacaaac atcccaatca tctggcattt aaaaatcatg cgtttttgat ggggcggtat
     3481 ctgactgtgt ttaaaacatt aggagccttt actccacagc ttccaaagat cacgatcctt
     3541 ttaatgacag atttcccatt atttgaagag caactgttag aggagggatt acggacattt
     3601 ttccgtaatg agtatcagct gatttttctg ccaacagatt atcgggggag agaagttgat
     3661 cttctgattt cgacaagtaa agtccaccgc aaaccatggg cggatcttga ctattttatt
     3721 gtgactgaag aactaaaatt aattgattac atccaactat ctcaaaaatt tgaaatgatt
     3781 caaaaacaaa aactattaaa acaataacaa agaaggagaa aaaagatgac atttgaagaa
     3841 attttaccag aattgaaaaa aggtgcaaag attattcgta aaggatggag tggatttgaa
     3901 ctttatgttg ttctcgtatc cgatgatgaa tttgatggct gtccggtgac gccgtactta
     3961 ttgatcaaaa caagtgacga aggtttttcc agcttcgctc ctacagtttg tgatatttta
     4021 gcagatgatt gggcgatcgt agaatgaaaa accagtatcc agatctagct aaacaggttg
     4081 tatttatcac aggagctgct tctggaattg gtgctgcgca agcccgagcg tttcttgaac
     4141 aagatgcttt tgtatttgga ttagatcaaa agttcggtaa aatggaagaa atttctttgc
     4201 gatttcctga aacttttgcc tacgcactag gtgatgttcg acaaatgaaa gaactccaac
     4261 aagcggtatc gaaatgccaa aatcattttg gtgaagttac gattttactg aatacagcgg
     4321 ggatattgga tgcctacaaa cccttgatgg aaactgacga atcgctgtgg gatctgattt
     4381 atgagacgaa tgtgaaaagc atgtatcagc tgacaaaaat catccttcct gatatgatcc
     4441 gccaaaaaag cggaacgatc atcaatatgg cttcgattgc tggcttgatt gctggtggag
     4501 gtgggatcgc ttatacaagc gcgaaacatg cgattgtcgg atttaccaaa caactcgctc
     4561 tggattacgc aggacagggt atccgagtaa aaggaattgc tccaggagcc atccaaacac
     4621 caatgaatgc ggctgatttt gaagggaaag gtgagatggc agagtgggtg gcaaatgaaa
     4681 caccagtcaa gcgatgggca cagccggaag aagtagctga gctgacgtta tttcttgcct
     4741 ctcctcaagc aagctacata caaggaacga tcatcccaat cgacggcgga tggttgttaa
     4801 aataaccttg tgtttttttc aagcttctgt atgataaaac taaagagaga aacaacggtt
     4861 gatgataaaa aaagtcgatg actgttcccg acattcgatg ccgaacagcc agttcaaaaa
     4921 attcttttta ataatcgtta atattcgaaa ctaagcggct tttcacgacc tcttgatata
     4981 aacgatattc aaaagcttgc aactgcggta acaagtccag ccaaatgaaa aatataagga
     5041 gctattttta tttgaccatt cttattactt gttgcagggc agctttttca ctaccttctg
     5101 cgacacttca gttggaattt tcttcccatc ctttggtcgc ggtcattacc aagataaaat
     5161 tatcttgcaa aggagaaata gaacatggaa aaaaataata cccgttcagc caaacgctgg
     5221 acaacgacag atgtgactcg gatggcgcta gtcactggtt tatatgtggc agtgacgctg
     5281 gttttgtctg tctttagctt tggagtgatt cagattcgtc tctcggagat gttcaactat
     5341 ctgtccttgt ataacaaaag atacatcgtc gcggtaacag cgggagtagc tttggctaat
     5401 attgcttctc ctcttggact gatagatgtt gcagtaggaa gcgtcagcac gctgcttgta
     5461 ttgcttatca actataaaat cactagtcgc atcaaaaaca tgaaaatcaa aatggccgtg
     5521 acagcatgcg tatttgcttt ttccatgttt acagtagctg gtcagctaac gattttatat
     5581 caactacctt ttttcttgaa ttggtgggtg attgctttag gagaattggc atcaatgatt
     5641 gtcggtggga taattattta ttggatcggt aaaaaagtgg atttgtcaaa ataaagatct
     5701 gtttaattta aaatagggca gcatggaaga gactgaatgt tgagtcttct tccatgctgc
     5761 ttttttgatt aatttgtatg aagaaatcga tttagccgtt ttttcatcaa gataccgata
     5821 taagctgctc cagttgcctt gattgcttcc ggcagtaaaa acggcagtag tccactggca
     5881 aatgcagttg taaaagtaag atcaccactt attttcagcc agatcgttcc gcagatcaat
     5941 gcagcaagag agcccattag attggcaaag attgcatata agtaatgagc atccgttctt
     6001 tcgatcatcc aaccagttat ccacgtttgt aagagaaatc caatcaaata tccgccagtt
     6061 ggcccaaata aaacagctat acctccagtc atccctgaaa atacaggaag accaatcaag
     6121 ccaagtaaaa gataaactcc aacagatatc aatcctagtt ttcttccgag aaaagttgct
     6181 gttaatccaa tagcaaatgt ttgccctgtc aaaggaacca aaccaaaagg aatggtcatc
     6241 tgagaaagga cagaaataat cgcggcaaat tccgcagcaa gtatcaattc tttcaatgtt
     6301 cggttcataa cgccctcttt tcgttaactt aatattttta tttggttaac gaaattgtaa
     6361 aacaaagtga ttactttgta aatagaaaat ataaaaaaag accagctatc caatagatag
     6421 cggtcttttt caagaaagct tttgaaatta taagctttgg ttgtagtatt caacgacaag
     6481 agcttcgtcg atttctggat atagttcgtc acgttctggt aaacgagtca atgaaccttc
     6541 caatttttca gcgtcaaagc ttacgaatgc tgggcgtcca acagttgctt ctacagcttc
     6601 ttttactgtt acgatgtttt gtgatttttc acgaactgag atcacttgac ccacttctac
     6661 gtggtatgaa gggatatcaa cgcgtttgcc atcaactaaa atgtgaccat ggttaactaa
     6721 ttgacgtgct tgacgacgag tcgttgcaag tcctaaacgg taaacaacat tgtctaaacg
     6781 ttgttctagt aagatcatga agttaacacc atgtttacct tctttgattt tgctagcttt
     6841 tacgaacaag ttacggaatt gacgttcgtt cattccgtac atgtgacgaa gtttttgttt
     6901 ttcagttaat tgcatgccgt attctgattg tttgccacgg ctattaggtc catgttgacc
     6961 tggtgcgtaa gggcgacgtg ctaattcttt tcctgtgcct gacaatgaga tgcctaagcg
     7021 acgagaaatt ttccatgatg gtcctgtata acgagacatt aaaatttcct ccaatgaata
     7081 taagtttttg gagtaaaata atccgttgaa aaattcataa tcatatagtt tgttcttcaa
     7141 tcttcacctt tgcagccgcg gttacacaat cgaacccgag acggggcaac aaactaggga
     7201 tgagttatta tttttctgct gcattatttt acacaaatta cagtatatga tagatcatcc
     7261 acgaatgtca agataattag tacataaaaa cgctttacaa acctaggctg tctttataaa
     7321 atgagagggt atgtgcaaat ggaaaaaagc gaaggaagtt taaggagaaa atcaatgaat
     7381 ccggtatcac cattatttga gaaaatcgat gcttcaattg aaaagaaggc gaatcttttt
     7441 gaaaacagct tttcacgtta cgctgttcga gcggttctcg cctgtttgtt tttgacttta
     7501 ggaacggctg tggcatttgc gatcgcgatg aagggggaag atatcgcgca tggtctagga
     7561 aagattttat acgcatttat gttcagctgg ggtctggtca tgattctata catgaacgcc
     7621 gaattaggaa catcgaatat gctttatatg accgtgggtg tttttcggca gagacttgct
     7681 ttaagtaagg cagccaagat tctatttgcc tgtatttttt tcaatatgat tggcggtata
     7741 ttatgtggat ttctaatttc tatgactacg ccatttcaag atttaacgtt ggacaacttt
     7801 atgttagaat caatagcagt aaaactagca aaaccttcag caacgatttt ggtggaaggg
     7861 atgtttgcga atatcgttgt caataccgct gtactgatca gcatgcggat gaaagaggat
     7921 gtcggaaaag tgatcacagt cgtattcatc attttcattt ttgctttttt aggatatgaa
     7981 cacgtgatag cgaattttcc tgcctttacg cttacttact ttgcttctca cggacagatg
     8041 gatggaatga cagtcagcaa tgtgttacat aatttgtttt ttgctttggc aggaaattat
     8101 attggtggcg gtttagtaat gggactggga tatgcttggc tgaatcagtc aaaatcatcc
     8161 tatgtggact aaaaagtcgt tcattaaagg ggaagtgcca tggaagtttt agtttttcca
     8221 aaaaatgagg aaaaagcgtt acaaatggaa aagtacatga aaaatctttt ttcctttgct
     8281 ggagtaccta agccggaacg cgctctttta caacaaccgt tactggatga gagcaaaaat
     8341 ttatctattt ctgaagtttt agcttttgtt cattattatt atgaacaaat cgaaagagag
     8401 tatcagtatg tagcgatcga tttagtccag aaaaacatca aacggcttac atttgaagac
     8461 ttagtcgtat tgttgccact agttcagaaa aaagaatggt gggacagcat cgactcttgg
     8521 agaaaagtat acagcacatg gtgtaaagcc tacccagagc agcgtgaaga agtctttcaa
     8581 ttgtttgaaa aaaaggaaga tttttggcta cgtcgaatag caatcacgtt gcaattaggt
     8641 tataaacagc aaacagacac aggactattg atccgagcaa tagacgaaga tcgtcaaaca
     8701 aaggaattct ttatccaaaa agcaattggt tgggcattac gcgattatag taagaccgat
     8761 gccgattggg taaaaagaca gctgacaaca gatttgagta agttagctgt tcgagaggca
     8821 agtaagtatt tataagaaag cgagacgaca agagatgaga cgcaaattat ttgcttttga
     8881 tattgatgga acgttgttag attcaaacaa acaagcttta gatagcacaa gagaagcatt
     8941 ggaaaaatta cgcaaagccg gtcatctggt cacgattgct acagggcgga gccgatttca
     9001 tgcgcaagag atcattcgcg atcttgattt tacgaactac attttatgta atggagcggc
     9061 cggtttttta gaccatgaac aagtatataa gaatttacta gatcgcgacc agttggatgc
     9121 gttcgttcaa gaagcgcatc atgagcagat cgatacagct tttgtcagct tagacaatat
     9181 caagcgttct tcttccaatg atgtaacggt gatggaagaa gcgatgcatt ctttcggtgc
     9241 tgtcttgcct gaattagatc agttttttgc agaggaacaa gaaatatacc aagcgttagc
     9301 atttttcgat caaacatatg atgggaagtt ctcttcatat gataaaattc gatttgtccg
     9361 ctggcatgag aacagtgtag atgtcgtacc taaaaatggt tctaaagcag cgacaattct
     9421 gcacttagca gaacaagtag gcatccctca tgaagacatc atcagctttg gcgatggaca
     9481 aaacgaccgt gaaatgttgc gcatgtcagg aattgggata gctatgggga atgctgtgcc
     9541 agaagtacaa gcagaagcta agatggtcac tgatacaaac gatcaggatg gaatttggaa
     9601 ggcattgaaa gagttaagcg tgatttaaaa gaggttgtga aaaagctgtt ctgcatcaag
     9661 taataagccc agccaaacaa aaatagctcc tcctattttt cgtttttctg ggcttattac
     9721 cgcagatgca agctttcgaa caccgtttaa ggaagaggtc gtgacagaag tggtcagttt
     9781 caagaaataa gaagggattt acgaaaattg cttctcaaat ttttgtaaaa ttacggctta
     9841 tttctgaaga agtagatgaa acaacgttta ttcgggaaat gggactgtga caagatgttt
     9901 gtcatagtcc cattttttta ttttattttt caaaactaag aaataccagg aaagagttcc
     9961 ttttgtttga ccttttcttt cttattgaaa acaactataa tatagagtga tgttaaaaga
    10021 gaagaggaat ttagtgtgcg ggtattgttt attggtgatg tagtaggttc aatgggacga
    10081 gagatgatta ctgaatatct tcctagattg aagaagaagt accgtccgca agtaacgatt
    10141 gtaaatggtg agaatgccgc ttctggacgt ggaatcacag aaaaaatcta taaaaaattt
    10201 ttgcaagacg gcgtagatgt cgtgacgatg gggaatcata cgtgggacaa ccgcggaatc
    10261 tttgagtttg taaatgaagc taaaaagatg gttcgtccgg caaattttcc ggaagggacg
    10321 cctggacaag ggatggtctt tgtcaaagtg aaccaagtcg aactggcagt gatcaacatg
    10381 caggctcgtt cttttatggt ggacttggat gatccttttc gtaaaatgaa tgagctggta
    10441 gaagaagcca gaaaacgtac gccgatcatt tttgtagatt ttcatggaga aacaacaagt
    10501 gaaaaacaag caatgggctg gtttttagat gggaaagttt cagcagtggt cggtacacat
    10561 acacacgttc agacaaatga tgcgcgaatt ttgccaagag gaacagcgta tctgacagac
    10621 gttgggatga caggtcccta tgatggtatt ttgggtatgc gcagagaacc tgtaatcgaa
    10681 aagtttctga ctgcattacc aaaacgtttt gaagttgtgg aacaaggccg atcgatttta
    10741 agcggctgta tcttggaatt ggatgatacg acaggtcatg caaaagaaat ccagctgatt
    10801 cagatcaacg atgatcgacc gttcatggag tagaaagaga ggcagttttt tgcagcagga
    10861 gccggaaatt caaaaagaag taaggaaact gacaaaactt ttaagagaga atgaaacgat
    10921 cattcgctac aaagaacttg aagaaaagat ccagcaaaac cagtatttag ctgagttgag
    10981 agaaaaaatc aaacaagcgc aaaaagatgc tgttcatttt gcccactatg acaaaccagc
    11041 agcagaaaaa gaagcaatca aacaagcgga tcaattcatg caagaatttg atcagcatcc
    11101 gcttgttgta gcttatagaa aacagctgtt ggaagcagat gatctgcttc atcatttaac
    11161 aactatgata caagaagaaa tcaatggaca aatagaggag gaaaaacatg cctcaaaaaa
    11221 ctaaaaatac tcctatgatg gaacaatatc taagcatcaa ggcccaatac caagatgctt
    11281 ttttgttcta tcgtttagga gacttttatg aactatttta cgaagatgcg atcaaagcgt
    11341 cacagctttt ggaattaacg ttgacgagca gaaatcgaaa tgcagaagaa cctattccta
    11401 tgtgcggtgt acctcaccat gcagcacaag gatatatcga tgccttgatt gaaaaaggct
    11461 ataaagtagc gatttgcgag caggtagaag atccaaagac gactaaaggg atggtcaagc
    11521 gcgaagtgat ccagctagtc actcctggta cagtcatgga cagcaaagga ttgtcggcaa
    11581 aagacaacaa ttttttaaca gctgtagtta gtcaaggaaa tgaatttggc tttgcttatg
    11641 ccgatttaag tacgggagaa ttgaagacgg ctcggttgca tgatgaagaa gctgttttaa
    11701 atgaagcctc tgcattgcag acaaaagaac tcgtattagg cagtgagatc actgataccc
    11761 ttcgtgaaca gctaagcggg cgtttagggc tagtcttttc tcaacaaaat gagatggaag
    11821 aaaacgcgga atttagcttt ttgacaagcg aactagtcga tccgctggaa aaagaagcaa
    11881 ccggcaaact attgacttat ttatcggtga cacaaaagcg gagtttagct catatccaaa
    11941 aagcagtaga ataccaacca gatcattttt tgaaaatgga ttattattca aaattcaacc
    12001 tagaattaag ccaatctatt cggactggga aaaagcacgg cactcttcta tggttgttag
    12061 atgaaacaaa aacagcaatg ggtggccgtt tactaaaaca atggctagac cgtccgctta
    12121 tccaggcaaa acaaattaaa gcaagacaag aaatggtcgc ttctttgcta gacagctatt
    12181 ttgaacgtat cgatttgcag tcagcattaa cgaaagtcta tgatctggaa cgcctagcag
    12241 gtcgagtagc tttcggtaat gtcaatgggc gagacttgat ccagctgaaa acttctttag
    12301 aacaagtgcc aatgatcaga gggttgattg aaggaatcga tcaaggtcaa tggcaaagtc
    12361 tgctttcaga aatgcagccg atggaccatc tcgtccaatt gatcgaccaa gctatccaag
    12421 atgatccgcc gttacaaata acggaaggaa acatcatcaa agatggattc aatgagcagc
    12481 tcgatatgta ccgttctgct atgagaaacg gaaagaaatg gttggcagaa cttgaagcaa
    12541 aagagcgtca agaaacagga atcaagaact taaaaatcgg atttaaccgc gttttcggtt
    12601 attatataga aattacaaaa gcaaatcttg gaaatgcaga actggagaag tatgaacgaa
    12661 aacaaacttt agcaaatgca gagcgtttca tcacaccaga actaaaagaa ttggagacac
    12721 aaatcctcga agcagaagaa aaatctgttg atttagaata tcagttgttt ttagctgtga
    12781 gagaagaagt caaaaaggct atccagccgc tacaagtact tgcaaaagca atcagtgcag
    12841 tagatgtgct acaaagtttt gcaacgatca gcgaacgcta tcagtatgtt cggccagaac
    12901 ttgtcagtga caagcatcag cttctgatca aagacggacg acatcctgta gtagaaaaag
    12961 tattaggaca tcaggaatat atccctaaca gcgtagaaat ggcagaagac gaaatgatct
    13021 tgctgattac aggaccgaat atgtctggta aaagtacgta tatgcgacag ttggcattaa
    13081 ctgttctgat ggcgcaaatg ggctgtttcg ttccggcaaa acaagcagtt ttacctattt
    13141 ttgatcggat ttttacccga attggtgcaa gtgacgactt aattgctgga caaagtactt
    13201 ttatggtaga gatgatggaa gccaatcaag ccctgcgtta tgctacgcca aacagtttga
    13261 ttttgtttga cgaactaggg cgaggaacag caacctatga cggaatggcg ttggcccaag
    13321 caatcatcga atatatccat cgtcatgtac aagcaaaaac actcttttct actcattatc
    13381 atgaactgac ggtacttgag aaagaacttc cgcagcttaa aaatgtccat gttggagccg
    13441 ttgaaaaaga cggagaagtt gtcttcttgc ataaaatgat ggatggacct gcggataaaa
    13501 gctacggcat acatgtggca aagatcgcag gattgccttc caatctacta gaacgagcag
    13561 cagatatcct gcatacgcta gaaaatggcg ataacggaca ccatactgtt ccagctgaag
    13621 tagaagagaa aactaaaaca gccaaacagg agcaaataaa accacctgca gaaaaagtaa
    13681 atcaagacca tatacaagac cgtgtaaaag aagaaaacca acagctttct ttattcagtg
    13741 aattatccga aaatgaaaca gaagtcattg aatcactgaa gcaaataaat ttactagaaa
    13801 tgacgccaat ggatgcacta aacacattat atgaattaca aaaacaactg taggaagaag
    13861 gcggatatcg atggccaaaa tccaagaatt atctgaacgt ttagctaatc agatcgctgc
    13921 gggagaagta gtggagcgac cagcttccgt tgtgaaagaa ttagtggaaa atgcaattga
    13981 cgccggcagt actcagattg atatcttagt tgaagaagcg ggactgcgga cgatccaagt
    14041 gattgataac ggagaaggca ttttggcaga cgacgtagag aatgccttca agcggcatgc
    14101 gacaagtaag atccataatc gcgacgatct ttttcgcata cgaacgctgg gctttcgagg
    14161 ggaagctttg ccaagtattg cctctgtttc tgaaatgact ctggaaacgg cgaatcagga
    14221 agaaaaacaa ggcacctatc tgtcgctgaa aggcggagaa gttattgagc atcgaccagc
    14281 accactgcgt caaggaacga agattaccgt cagcaatctg tttttcaata cgccagcccg
    14341 cttgaaatac gtgaaaacac tgcacacaga attagcgaac atcggggaca tcgtcaatcg
    14401 actggcattg agtcatccat cgattgcttt tcgtttagta catgatggaa acaaaatgct
    14461 ggcaactgct ggaaatggcg atctgaaaca aacaattgcg ggaatctacg gattatctac
    14521 cgcaaaaaaa atgctgaaaa tcgaaggaaa agatctagat tttgagttat ttggctatgt
    14581 ttcattgcct gaggtgactc gtgccagtag gaattactta tcgacgatca tcaatggacg
    14641 ttttatcaag aacttttcct tgaataaagc aatcgttgca ggttatgggt caaaattaat
    14701 ggtcggtcgt ttccctattg ctgtattgga aatcaaaatg gacccgcttt tagtagatgt
    14761 aaatgttcat ccgacgaagc aggaagtccg gctgtcgaag gaaaaagaac taacagagct
    14821 aattagtaac gccattcaaa aagcattgtc tcaagaaaat ctgattccaa gtgcagcgga
    14881 taatctacgg tttaagaaaa aagtacctga tcagcctaaa acagaacaaa tcgaaatcga
    14941 tttgtcctac gcttttgaag aagaaaaacc taaaaagcca agtagtttga attttgatcg
    15001 agagacaggt acctttttcg tagaagaact aaagaacaca tttgttgaca gaattgttga
    15061 taagtctgtg gaaaatgttg aaaactattc tggtttttct gaagaaaaca ccacttatcc
    15121 agaaaaaaca gcgaaaacgg tggataagtt tggtgaaaat gttgataact ttgtagaaaa
    15181 aacagtggaa aaatctgaaa agaaagaatt tcccattgtg gataacatgg agaaaacaaa
    15241 tgaagaacaa gcagataaat ccgtagaaga ggatgaaaag atttacgagg aagaattgac
    15301 actccatcct gaatttgatt tcactcaagg aaacgacaaa acattagaac aagccatcaa
    15361 gaaattagaa acggaaaaac cagtacaacg ttttcctcag ttggaatatt ttggacagat
    15421 gcacggaacg tatctttttg cccaaagtag cgatgggttg tacatcattg atcagcatgc
    15481 tgcccaagag cgcattaagt atgaatattt ccgggaaaaa attggggaag tatctgatga
    15541 tctgcaagaa ttgcttgttc catttgtgtt agactatcca aacagtgatg ctttgaaatt
    15601 aaaagagcaa aaacacttgc tagaagatgc agggatttat ttagaagaat ttggtcaaaa
    15661 cagctttatt gtacgggccc atcctacttg gtatcccaat ggagaagaag aatcgattat
    15721 tcgggagatg atcgatatgc tgctgacaac tggaagtgtg agtgtaaaaa aattccgtga
    15781 agcaacagca atcatgatga gttgcaaacg atcgattaaa gccaaccatt atttgaatga
    15841 agcacaagca cgtgtgctgc tgaaggatct ggcacgatgc gaaaatcctt tcaattgtcc
    15901 ccatggccgt ccagtattga ttcactttac caattcggat atggaaagga tgttcaaacg
    15961 aatccaagac ccgcattaag tcaaagagaa gagggaaaac atgaagattg tattagcatc
    16021 ccaatcacca agaagaaaag agttattggc tcatatcgtt tcagaattcg agattgaacc
    16081 tgctgatatc gatgaaacgc catttccaga cgaacagccc gtcgattatg ttcgtagaat
    16141 ggctgaagaa aaagcacgaa ctgtctggga acaagatgaa aaagaagacc atttagtgat
    16201 tgccagtgac acgactgttg ttctcaatca agagatcatg ggtaaaccag aagatctggc
    16261 tgaggctgaa ttcatgctga aaaaactaag cggggaaaca catactgtat atacagctgt
    16321 tgttttaaaa acaaaggaac gagaagaacg gatactagca gaagcacatg tcacttttta
    16381 tcctttgaca gacgaagaga tcaaacgcta cttggagacg ggggattatg cggataaggc
    16441 aggggcatac ggcatccaaa atgctgcgag tgtattcgtc aaagaaattt ctggagatta
    16501 ttacagtatc gtaggatttc cgattggtgc tgtcaatcag gcactgaaaa cattcattta
    16561 aacaaaaaag cggactatct gattttcgat tgaaaatcca tgatagcccg ttttttttat
    16621 tgaaaagatt acttatctac tctgactaag attttacttc agctttaccg actgcttcgc
    16681 ccgggcgaac aagtcctgat tggtcaagag aaagtcctgc aactttttca ttattggtca
    16741 aagcaacaat aatgtcagtt ttcttgccag cttgttctat ttctggcaaa tccatttcag
    16801 caatcagggt ctctggtgtg acaaggtatc cttctttcac gaatacattg aaaggaacac
    16861 cctttagttc aacagtatct aatcccatgt gaacaagtac ttccagcccc tcattagaaa
    16921 gaataccaat ggcatgtttt gtttcaaaga cactcgtcac tttaccgttt actggtgcat
    16981 agactttgcc gtttgacggt tcgacagcat aaccgtcacc catcattttt tgtgagaaaa
    17041 ctgggtcatt tacttcagtt atttccttga tggtccctgc agcgactgcg aataatgttt
    17101 cttttgttgc aactgccgta ccagttgctg aaacaggttc gaaagactgt ggcgttgctg
    17161 ttgcgccatt tgctgtttga agttgtacat cagcagcatt ttcaggaaca gcaggatcaa
    17221 tcttattcaa aattccctga cgtctaaaga tgatcgtcaa gccaaatgga atgatgacag
    17281 caatgatcat tgcgatgatg aaaggtaccc atgtttctgc ttggatagct agtattcctg
    17341 gcaaaccgcc tactccgatc gcgttagctc gaacacccat caagttagca aacatgccag
    17401 ctaatccaga gccgaccatt gcagcgacga aaggatagac gtatttcaaa ttgattccga
    17461 acatagcagg ttcagttacg cctaagtaac aagaaatcat tgctggaatc gagatttgtt
    17521 cttctttttt attcccacga tgtaagaaga tgatggctaa gactgcagag ccttgggcga
    17581 tatttgataa agcaatcatc ggccataaat tcgttgatcc gaaatctgca atcagctgca
    17641 tatcgatggc attggtcata tggtggagac cagtaatcac taaaggagca tacaggaatc
    17701 cgaatacggc actaaacaac cagctgatag aagacgtcaa tccagtattt acgatatttg
    17761 agatccagct tccgactgtc cagccgatag gacctaaaat aacgtgtgca gctaaaacag
    17821 ttggtaacaa tgaaaacaat ggaacaaaaa tcatcgagat cgactgaggg atatatttgc
    17881 ggaagaagat ttctagatac gctaacataa accctgccag catggctgga ataacttgcg
    17941 cttgataacc aatcatctgg acttgagcaa aaccaaaatc ccaaaatgga atatctgctg
    18001 cggctgtgga agctacacta taagcattta ataattgcgg agaaactaac gtaattccta
    18061 aaacgattcc taatatttgt gtagtaccca tcttttttgc aatactccaa gtgataccta
    18121 ctggaagaaa atggaaaatt gcttcaccgg gtaaccacaa aaaggcattg acaccattcc
    18181 aaaacttcga gtgttcaacg attgttccac caagactttc aaactggata ccttcaagta
    18241 catttctgaa tccaaggatc aatccaccga caatgattgc aggaatcagt ggtgtaaaga
    18301 tttctgctaa aacggcaata gcacgttgaa cgggatgaag gttttgtttt gcagctgctt
    18361 ttccttgttc tttggaaacc ccttcaactc cagatactgc aacgaagtcg ttataaaaag
    18421 tagaaacatc gtttcctatg atgacttgga actgtcctgc attcgtgaac atccctttta
    18481 cgctaggtat atcttcgatc gctttttcgt ccgcttttcc tggatcattc aggacaaaac
    18541 gcatacgagt cgcacaatga ctaactgcag caatattttc ttttccgccg atatcatgta
    18601 acagcttctc ggcatctgct tgatattttg ccatatcaat aaaccccttt ctcttaactt
    18661 gtctatgcaa gttgtttctt catttactat actttttttc ggagagaatt gcaagcgttt
    18721 tattaaaaag tacgagagaa aatgatatcg ttttaaaaag cttaaaataa gcttttctta
    18781 aaaataggaa cattgaaata caaaaagagc tgtagtatag tgaagaaatg atggaagaac
    18841 gagtgaggga aaaaacatga ataagttcaa tgaaattttt ttagatttgg aacagaaaat
    18901 tttagcgaaa gaatatcctc cgcattcgct tttacccagt gagaaccaat tgatcaaaat
    18961 ttatggtgtt tcacgagaaa caattagaaa agcgctgaat cttttgacta cggaaggtta
    19021 tattcaaaaa aaacaaggaa aaggttcgat cgtactggat cggaatcgct tcgactttcc
    19081 tatttctgga ttgactagct ataaagagct acaggagacc caacgtattc caagtgaaac
    19141 gatcatccat acgttagaag aaacagaagt gacaaaagca ttgaacgaga tcactggctg
    19201 ggagatcggt gcgcctgttt ggcatttgat acgcgaaaga aaaatcaatg gcgaagtagt
    19261 tatattagac accgattatc tattaaagga aatcgttcct attttaactc cagcacaagc
    19321 acaaggatcg atctatgaat attttgaaaa tgagctttct ttgacgattg cttacgcgca
    19381 aaaggagatc acagtagaag aagtaacgga aatcatgaaa acagcgatgg atcttcacga
    19441 tgacacttat gcagtagtag tcagaagcct cgttcatctg gaagataccc gctgtttcga
    19501 gtattctgag tcggttcacc gattagataa attccgtttc gttgagtttg cccgacgccg
    19561 aaaagtgtaa atagttcaaa agaaagcaaa ttgttggcat ctgtccactt tggcgctatg
    19621 ataggatcac aaagggggca tttttaatgg ataaaccaat aagaccagaa aaagaagaac
    19681 tgaaagaaaa gttatcaccc atggcttatg cagtcacaca agaaaatgca acagaacgac
    19741 catttagcgg gaaatatgat gatttttacg aaaaggggat ctatgtagat atcgtcagcg
    19801 gtgaaccgtt attcagctct gcagaaaaat atgatgcagg ttgtggctgg ccatcattca
    19861 gcaaaccaat aacgaaaaga caagtgcgcg aaaaagccga tttttctcat ggcatgcatc
    19921 gaatagaagt tcgaagcaaa gaagcagatt ctcatctcgg acatgtgttt accgatggac
    19981 cagtagatca aggtggtcta cgttactgca tcaattctgc ctcactgaaa ttcattccat
    20041 atgaaaagat ggatgaatta ggttatgggg aattcaaatc acttgtagaa taatggaaat
    20101 acacaaagag cggtacaata cggggattta ctcgatcgtc cgctcttttt ttattcaagc
    20161 gattgctatt tgaaagaaac gctccctaga ctcctttttt cacaaggtga aatgtgctac
    20221 aataaaggga acgtatgtgt gcaaaagaaa gaggactaga atatgtatga atatctgaca
    20281 ggtgtggtta cctttatcaa cccctattac atagtagtag aaaccaatgg tatcggctac
    20341 cagatcgcac taggaaatcc ttaccgctac agtagcaaac taaatcaaaa aataaaaatt
    20401 tatgtccatc aggtaatacg tgaagatgcg catcttctgt atggatttga ttcgctagaa
    20461 gaaaagcaac tgtttttgcg attagtaagt gtttcaggaa tcggtccgaa aagtgccctt
    20521 gcaatcatgg caagcgaaga ccactccggt ttgattcaag cagtagaatc cagtgatgtc
    20581 acttatttga cgaaatttcc aggagtaggg aaaaagacag cacaacaaat gatcttggat
    20641 ctaaaaggaa aattcggtga gctgagtatc gatacacctt ttagtctatt tgatgaagca
    20701 aacacaaaag acgctacagc tctatctgaa gcaatggaag ctctctcggc tcttggttac
    20761 agtgatcgag aaatcaaacg tgtagaaaaa caattaaaag aagtagataa tcagacaacg
    20821 gatgagtatc tacgccaagc actcaagcta atgatgaaaa aataaggagg agaccaaatg
    20881 acagatgaat acttgttatc accagaatct ggcgaaaatg aactgagttt ggaaaaatct
    20941 cttcgaccac agctgctttc tcaatatatc ggacagagaa aagtcaaaca agaacttcag
    21001 atttacatcg aagctgccag aaatcgggaa gaacctttag atcatgttct gttgtacggg
    21061 cctcctggat taggaaaaac gacgatggcc atggtcattg ctaatgagat gaccgtaaat
    21121 attcgtacga cgagtggccc tgctatcgaa cgtccgggtg acttagtagc aatcttgaat
    21181 gaactggaag caggggatgt cctgtttatc gatgagatcc atcgattacc tagagtggta
    21241 gaagagatgc tttattcagc tatggaagat ttctatgtag atatcatggt aggacaaggg
    21301 ccaaccgcac atccggttca tttccctctt cctcccttta ctttgattgg cgcgacgaca
    21361 cgggcaggta tgctttctgc acctttacga gatcgatttg gcatcatttc tcatatggaa
    21421 tattatgacg aacaggatct gcaggagatc gttttacgtt cttcggatat ttttcaaaca
    21481 gagatcattg aagaaggggc attggaaatt gctcgccgat cacgaggaac gcctagaatc
    21541 gctaatcgct tgctcaaacg ggttcgtgat tttgcgcaag tccaaggaga cgggaaaatc
    21601 gatcgtccta tagcggatca ggcacttact ttgctacagg tcgatcaggc tggattggat
    21661 tatgttgacc agaaattgtt gcgaacaatg atcgagttat atggcggcgg accagtaggg
    21721 ttaagtacgc tttcagtaaa cataggagaa gagcgtgaga cggtagaaga tatgtatgaa
    21781 ccgtatctga tccaaaaagg atttttaaag cgtacaccta gagggcgaat tgctactgct
    21841 tatgcctatg aacattttgg ttacgactat catatatgat ttttgctttt agattggagg
    21901 aaaatgaatg agtgatacaa cacgtacgaa acaattgatc aaaaacgtat tgattgattt
    21961 gtgccaaacg caatcttttc gaaaaatcag cgtccaaaaa atcgcaaacg aagcaaaaat
    22021 caatcgacaa acattttatt atcattttac agataaatac gatttgcttc gttgggtcta
    22081 ttgtgaggat gcattgcatt atttagatcc acaatgtctt tcacttgata attgggaaga
    22141 gcaagcattg aaaatgctga aagcaattgc tgagaagaaa gaattttatg caaatactgt
    22201 gctttctgac ccagaaattt tacaaaaaga gttttctcaa ctgatccaaa aatcatttat
    22261 caagattttt gaacaaatgg atgaagaaag acaactttct gcaagagaca aactatttta
    22321 tgctcgtttt ttttcttacg gttgcagtgg tgtattagtc aattggatca cgaatgaata
    22381 tgaagaaaca ccgatggaaa tcgctatgca gcttttccgt ttagccaagg atacggaatt
    22441 atattcttat cgtctttatg caaaagaaga gttggaagaa cagtaataga aaaatttttt
    22501 gttggaaaag caataatcgc taaaaggaga tggggaaatg acaaaaattt tatttgtttg
    22561 tttgggaaat atttgccgtt caccgatggc agaaggcttg ctgagaaaac gaatagcatt
    22621 agaaggaagg gaagcagaat tttttgtgga ttctgctgct acaagcacgt atgaagttgg
    22681 aaagacaccg caccctggaa cgaaaaaaat attaaaccaa gaaaaagtag atatgacgaa
    22741 tatggttgct cggcaaatca caccccacga ttttgaaact tttgattgga tcattggcat
    22801 ggatcaagaa aatgtagaag aactgaaacg aagagcacca cgctcagcgc aggggaaaat
    22861 ccatttgttt ttaagtagca ttcctggaaa agaaaaagaa aatgttcccg acccatacta
    22921 taccaataac tttgatgaga catatcactt gatcacagaa ggcctgaatc attggtggaa
    22981 tatttggatt gatgaaaata aaataacaaa caatttgtaa agttaacgct ttctttttaa
    23041 ggcgatgtta gagcatttcc ttgttttttt gtaaaatgtt aggtaaaata aaattaatta
    23101 agtaacactt tcttagctaa aggaggagtg cattcgatga acgaagagac agtatcgcca
    23161 atgaagaagc ttacgaagtt agttactcat acttcgtatc aactttttga ttcttttgta
    23221 aatgacactg aagaacatgc taagaatgta cgattgcaag gaaagtttat tcttgagctg
    23281 caaaaagctg ctactgaaca tagtctagtt atcttacaag taagagcaaa tcgtttgagt
    23341 agcaagtatg aaacgatctc aggctgggtg gcgacaaaaa cggtcgaaaa agaccgagtg
    23401 atgatccgcc tacaaaacga agagcagcag atccggatgg ttcctgtaga acaaattgaa
    23461 aaaataacaa tcctttcacc agcaggggaa caggaacggt tatcaaaata atttatacca
    23521 gatagaaaag cacgtatgag cttgtaccat caatcattac taatcaaaaa taaccgaatg
    23581 ctttaagctg atatcagtaa aacggaacgt tttaggatga gtatcacagc atgacagcat
    23641 tgggttgatt agttgaatcg attggatggt acaagttttt ttgataaaaa aaggtcctgc
    23701 tagccgggga gctagcagga taaggagtta aaaatgaaaa agtgttgtta gggttgtttg
    23761 ttggtatgct tatataatag tcactagttg tgaatatttt gtgacgaaag ttttcgaaag
    23821 ttgttaagtt tttttgcgaa aactattttt atatcatata tatgtctaaa atctatatta
    23881 t
//
LOCUS       DAFKHN010000041        23790 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFKHN010000041 DAFKHN010000000
VERSION     DAFKHN010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.041"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..921)
                     /locus_tag="LY912_001624"
     CDS             complement(<1..921)
                     /locus_tag="LY912_001624"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HBM6955310.1"
                     /translation="MSISFSNNGRKSFSGKEVQIQYAALDIYWNIFSSTATEFYDEDP
                     QVVAFMMNTFFKKEVLDRLNSGMIDKLYFLLKICKENFPATSVKDVQKEFTEYEYIDF
                     FIDLSVDILRPNLPICREQRILVNILARLSITKIESEETSLEQYKLLKKANVPHVLYS
                     REMVESLCTVFDLFIPEKEKILYSLAFARNKLYNGFLNFNQPNTPLPTFMLYQEHSVL
                     KEVQTAIEQFYMDFREQNQHLLPVILEKENVQWMVEDLVHLYDRYKKQPRIVIGVNYT
                     RDFYISKDLIVKIEQIFSNESIKIQNDFMEN"
     gene            complement(928..1362)
                     /locus_tag="LY912_001625"
     CDS             complement(928..1362)
                     /locus_tag="LY912_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955311.1"
                     /translation="MQTQEAIKTFILKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISFSQQTNYSASYLYTKMKKINAFLA"
     gene            1510..2651
                     /locus_tag="LY912_001626"
                     /pseudo
     CDS             1510..2651
                     /locus_tag="LY912_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(2777..3856)
                     /locus_tag="LY912_001627"
     CDS             complement(2777..3856)
                     /locus_tag="LY912_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBM6955312.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(3959..4399)
                     /locus_tag="LY912_001628"
     CDS             complement(3959..4399)
                     /locus_tag="LY912_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBM6955313.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(4456..4866)
                     /locus_tag="LY912_001629"
     CDS             complement(4456..4866)
                     /locus_tag="LY912_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBM6955314.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(5046..5480)
                     /locus_tag="LY912_001630"
     CDS             complement(5046..5480)
                     /locus_tag="LY912_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBM6955315.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(5580..6428)
                     /locus_tag="LY912_001631"
     CDS             complement(5580..6428)
                     /locus_tag="LY912_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBM6955316.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            6817..8583
                     /locus_tag="LY912_001632"
     CDS             6817..8583
                     /locus_tag="LY912_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBM6955317.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            8685..9944
                     /locus_tag="LY912_001633"
     CDS             8685..9944
                     /locus_tag="LY912_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBM6955318.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            10091..11392
                     /locus_tag="LY912_001634"
     CDS             10091..11392
                     /locus_tag="LY912_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6955319.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            11395..12246
                     /locus_tag="LY912_001635"
     CDS             11395..12246
                     /locus_tag="LY912_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6955320.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            12259..13074
                     /locus_tag="LY912_001636"
     CDS             12259..13074
                     /locus_tag="LY912_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBM6955321.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            13225..14391
                     /locus_tag="LY912_001637"
     CDS             13225..14391
                     /locus_tag="LY912_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBM6955322.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            14621..15268
                     /locus_tag="LY912_001638"
     CDS             14621..15268
                     /locus_tag="LY912_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBM6955323.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            15352..16296
                     /locus_tag="LY912_001639"
     CDS             15352..16296
                     /locus_tag="LY912_001639"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBM6955324.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            16431..17882
                     /locus_tag="LY912_001640"
     CDS             16431..17882
                     /locus_tag="LY912_001640"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBM6955325.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            17903..18739
                     /locus_tag="LY912_001641"
     CDS             17903..18739
                     /locus_tag="LY912_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBM6955326.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            18739..19398
                     /locus_tag="LY912_001642"
     CDS             18739..19398
                     /locus_tag="LY912_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBM6955327.1"
                     /translation="MYFPLIDLSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            19524..20213
                     /locus_tag="LY912_001643"
     CDS             19524..20213
                     /locus_tag="LY912_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955328.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            20219..21175
                     /locus_tag="LY912_001644"
     CDS             20219..21175
                     /locus_tag="LY912_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBM6955329.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            21219..21731
                     /locus_tag="LY912_001645"
     CDS             21219..21731
                     /locus_tag="LY912_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955330.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(21987..22535)
                     /locus_tag="LY912_001646"
     CDS             complement(21987..22535)
                     /locus_tag="LY912_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBM6955331.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(22624..23787)
                     /locus_tag="LY912_001647"
     CDS             complement(22624..23787)
                     /locus_tag="LY912_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBM6955332.1"
                     /translation="MIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGFVLLRTT
                     FGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISAIIGILR
                     YIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFLSEKRLF
                     TMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEEKEDELI
                     IEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGITFQEILG
                     YIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTAIISVFL
                     VSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLLV"
BASE COUNT         8016 a         4272 c         4538 g         6964 t
ORIGIN      
        1 gttctccata aaatcatttt gtattttgat cgattcattt gaaaaaattt gttctatctt
       61 aacgatcaga tctttactga tataaaaatc acgcgtatag ttcacaccaa tcacaattcg
      121 cggctgtttt ttgtagcgat catacaaatg tactaggtct tcaaccatcc attgcacatt
      181 ttccttttct aaaataactg gtaacaagtg ttgattttgt tctctgaaat ccatataaaa
      241 ttgttcaatg gcggtttgga cttctttcaa tacgctatgt tcttgataaa gcatgaaagt
      301 aggaaggggc gtatttggtt gattgaagtt aagaaatcca ttataaagtt tatttcgtgc
      361 gaatgccaat gagtaaagaa tcttttcttt ttcaggtata aacaaatcaa atacagtaca
      421 aagggactcc accatttctc ttgaataaag aacatgagga acgtttgctt tttttaaaag
      481 tttgtattgc tccaagcttg tttcttccga ttcgattttc gtgatagaaa gtcgagctaa
      541 aatattcact aagatgcgtt gttcgcgaca aattggcaga ttaggtcgca aaatatctac
      601 agagagatca ataaaaaagt caatatattc atactctgtg aattcttttt gtacgtcttt
      661 cacagaagtt gcaggaaaat tctctttaca tatttttaat agaaaatata atttatctat
      721 cataccgcta tttagtcggt caagtacttc ttttttaaaa aaagtattca tcataaaagc
      781 cactacttgc ggatcttcat cataaaattc tgtagcagta cttgaaaaga tgttccaata
      841 aatatctaat gctgcatatt gaatttgtac ctcttttcca gaaaaagact ttctgccatt
      901 attagaaaag gagatagaca aaccgtacta tgctaaaaat gcattaatct ttttcatttt
      961 cgtatacaaa taagaggcac tatagtttgt ttgctgactg aaactgataa tcgaatttgt
     1021 ctgacagctg aacaaagaag tcaagatctg ataactgact gattcgttgc agtatcttcc
     1081 aaatagacga taatagcagt aagccggatc aattccttca aaattcaact ttaaaaaagg
     1141 tttttgctta tcaatatgca gttctgttag attgagacgc tcaaagtctt gttctaattc
     1201 tttgatgtat agtaaaaaat ttgattcaga catatggaaa tgatctgcta aatattgtgt
     1261 agtaataaag aaacgatgtt cagataggaa aagaaaaata tctaattttg tattgctttt
     1321 tttcttcaag ataaacgttt taatcgcttc ttgagtttgc atgaaagagg ctccttttta
     1381 cttaaattgt taaaacttga aaatattact gtttttttca taaatttaga caaaaaaaca
     1441 gtaaacatat aggtagaatc tctactatct tatttcttgc atacaaaaaa atcaaggagt
     1501 gagagagtta tgagatattc aaccatctta atatcaacat ttgcagcctt aagcttatcg
     1561 cttactataa atcagacagt ccacacagag gagacagaaa cagccaaatg gacagaaacc
     1621 aagtgggcca acgtcaatcg aattaccttt caggatgaat tttcatcctt caattcagga
     1681 gtcgcaaaat taagaaaagg acaaacagcg accatcaaag caaaaattga ctattcggga
     1741 gacttagcac ctatactaca atcagctgtt acatttgaga atgttgatcc cactttgtcg
     1801 attggctatg acgagaacac tttgactatc caacacaagc aagcgatatt taccttcacc
     1861 gttacattaa atcaggactt gttaaaacca gcgcttttta ctgtcaaggt atcagatgga
     1921 ctaccgaacg atcatcattt aacgccgtat agtcagcggc agacaattga gcaagattca
     1981 gccatcgact caggaggaga tcttgttgaa gaaccaacag ataaaccaga aaatgaaaat
     2041 aagccagaag taccgcctac agaaaatcca gacggagaac agaaaccgga aatagaacct
     2101 ggagaagaac ccgatacaga aactcaacca gagccagaca ataaatcaaa acctgaaata
     2161 acccctggag aaaaaccaga tgtaactcca gaaccagata cggattctgg aaaccaaaca
     2221 gtaccggaaa caaatccaga cacagataat gaaactgaaa atccagaaaa accagaggta
     2281 gatccagaag aaaaaccaga tgtgactcca gaaccagata cggacgcaag agaccaagga
     2341 ataccagaaa aaataaacaa aaaaacaatt caagaggatg gaaaaaaaga gagtaaaaaa
     2401 tcaaatctag caattctaaa aataaatgaa gagcagctga ataaaaaatc acgaatattt
     2461 gatagcgccc aatcagctga aaccttaaaa agtagcaagg atacaacctt tgctgtcctg
     2521 aaacgaaaaa taaacagcta ccaaaatccg gagagtcaca aaacaaagtt atactgtgga
     2581 gcggaatcat tctattaagt atagcaacaa tgctttctgc aaaaagattt aaacaaaaca
     2641 gatctctcta acatttgaat aatgtctgtg aacgcatttt tcaaataaaa agaaatatcc
     2701 agaaaatgac cccaaaatac cagattgaaa tctgatattt ggggtcgttc atactttatc
     2761 tttcttcata tttattttaa gggatatctg tttcttttgg aagatggttc gggatctttt
     2821 tcactttcaa tacatctaaa aagaaggtaa agatcggaat gccgacaatc aagccccaaa
     2881 cgccaaagaa ccgttcgcta acaagtaaga ccacaaatgt ataaaaaatc ggcagttctg
     2941 ttttgctgga catcaacttc ggattcagca cataagactc aattagatgg acaatcaaaa
     3001 tcgtaatcag gatataaaca acatctcgga tgcctccttg ggaataagct atgaaagata
     3061 gaggaataca agaaatgata acacctgcta ctgggatcag acttaaaatg aaaatcatga
     3121 tcgctaaact cagcagctga tgaaagccaa atacagccaa ggcgattgta gtgagcaacg
     3181 tatttaaaag agcgacaaca aattgagctt ctaataccaa accaaatgta ttgacaaact
     3241 tatcggcaaa atagtaaata tcttgaaaga accaagaaaa ttcacttttt aaaaacaatc
     3301 ttgagaatac aattgttttt ttcttttcaa tcataaaaaa gaaacttaag atgaatgaca
     3361 tagcaaacgc cactgccatt tttcctatat cctgtaaata gccaagcgca atcgaagcgc
     3421 cattttgaag ctgttcaaaa aaatcgtttc gctcaatata agtatggata tattgtaaaa
     3481 caggatctgc atcttttggc tgatgctcgt aaaaattaat aacggactgg atcatgtcaa
     3541 atgtttgatg aataagcatc gggatatact ttgtgaatgc cagatagata aggtaaacga
     3601 tcagtgtata aatcatgata gctaaaacac ctgtagggat tcggacaaat cgctgaatga
     3661 tttgaacaag atgaatcatc aaataagtaa agataaatgt gagcaaaatg gttgtaatca
     3721 tacttctaac taagaaaaga acaaaaacga caaataataa aacagtgaga cggcgtattt
     3781 tttcattcgc caaaaaacgc tgataaacgg tcaaatcgac aacctccaaa taacaaaaaa
     3841 taaacacgtt attcattata tgatggaata tgaaaataag aaagagcaaa aagaaaaacc
     3901 gctaaatgac gttatcttat gagttggttt tcctcataaa atcgttcatc tagcagtttc
     3961 agcccttttt ctggtcttga tgaaaattat ctagcatttt tcgggtcaga tgttgcagtg
     4021 tatccaattc ttcctgttca agtggaagat aagacttgat cttttgtgga ataccttctg
     4081 cttgtttttg caacgcagca ccttgagcag tcagcgtaac atttacgatt ctttcatcac
     4141 ccgtttcacg ctgacgatta atataatttt tttctgctaa cttttttagt aagggagtca
     4201 gcgtaccaga atccagacac aaatcatttc ctagctcttt cactgaagtc tttttctttt
     4261 cccataaaac taacatcaca agatactggg tataggtaag attcagcggc ttgaggaggg
     4321 gagtgtagtg tctaatgatt tctttagagg cggcatataa aggaaaacat acttgattaa
     4381 ctaaatatag atcttccatt tttccacctc cgctgtttta ctatagtgta tcatagcgga
     4441 tttacacaaa aaagtctatt cactaactgc tttcagagta acttctatat ttccagctgt
     4501 agcttttgaa tacggacaca ctttatgcgc tgcctctaat aattcttgcg tttcttccag
     4561 agaaagacct tcgatagatc cttcaatctc tacacctaag acaaagctcg tttcactttc
     4621 tgaataaagg gaaacttgtg cactgacagt agaagcccca gagatatttt tttgctgttt
     4681 gatcaattct aatgcactgt taaaacatgc actgaaacca gctgcaaaca attgttcagg
     4741 gttggttgca ttttcgacgc gtttaccagg agctgcaata ttcaattcga atgtacgatc
     4801 gggattatgc acttctccag agcgtccgcc tgtgttgatc attttcgtag aatacatttt
     4861 tttcataaaa ttaccacctt taattatatt ttatacaatt gaattttaca caatataatt
     4921 gtggaaagca aagaaatgga ttggcataag ataaataaga gaaagcacat gaaacagacg
     4981 cgctttctcg aatagcaaac atatacaaaa aatatcagag acaaaaaata atctcatcat
     5041 aaacattaca tatatttctc aaaaagttgt tttctttctt caaaaattac ttcacgatgg
     5101 acctgatgaa gcatccataa ataaccaaaa ggatctctga acattgagtt agtcacacca
     5161 aagtccatca tttctgtcat ttcttgaatc tctacacagc catttcgtaa tgctttatta
     5221 tgtgtgtcct cgatatcaga gacgatgata ttgaaccaga tcgtatttgg atgttcagca
     5281 gtaggagcag tcaaaccaag agacgtgttt tcatccagca tatggaatct cgtaccatac
     5341 aaggtaaaaa tgacttcatt attgcctcta gggtaatctg ttgcctcaat cagttgtatt
     5401 tcatcaaaga ttgtttgata cagttctagt gctttcaaac tatcatttaa tacaaaatcg
     5461 atttccgttc ctttatgcat aaagatctcc tctccttttc agtcgaacag ttactagatt
     5521 cttttattat accagctaaa gaaaacgcat tcaaaaaaat agcggattta cttaccaact
     5581 cattcgattg gatgataagt aaatccgcgt cccattactt ctgctacgct gctgacaatg
     5641 acaaaggcac ttggatcgat ttcttctatc aatggtttca ttcgggaaaa ttcatgatca
     5701 gtcacaacga tcaataaaac ctcttttgac tttcgattat acccgccttt tgcctctagc
     5761 agggtaaggc cacgtccaat ctcagcactt aagcgaaggc ggatgtcttc caaataatgt
     5821 tcactcatga ccataacaga tttctttcga ttgatacctg tttcgatata agtcatgaca
     5881 attgaagtga ttgcaataga taaaatagca taaagaaact cttctattcc aaaaataaac
     5941 agattaagag aaacaacgaa tgcgtctgta aaaaataagc caatcgaagt attcaagtgg
     6001 aaatattttt taaaaatgag gggagggatc gtcgtaccgc cgctagaaga gttgttttta
     6061 tataaaatcg caactcctaa agcaaaaatc gcacttccaa aaatgacaga caacaaccga
     6121 tctgaagtaa tcattgtttc tggaactatt gcaatgatta aaggaaaaac caagcttccg
     6181 aaaagtactt taaaaaaggg ttttttacct aaaaatagaa gagctagtac caacataacg
     6241 atattcaaca ctaaaataac tatagctcgg tcaaagccta aagcagcttc cagtaatatt
     6301 cctagaccgc tgacacctcc agcagcaata tgatgaggcc ctaaaaacat attgatagcg
     6361 actcctaata tgaagagggc aaaaataatc ttaatgtatg tccatataaa ttgtctcgtt
     6421 tctttcattt attcacttcc ttaattcatt aataatactc ttatcttatt ataacttact
     6481 tttcacctta agttaacttt aattaataaa aaaattaggc tagtctaaat tattatgttt
     6541 cattcttcta gaatatactt ctacgccaaa aactgttaaa aaacttttac tttagaaaat
     6601 tggagaaatt gatcgcttaa gataaattca ggacactaaa tagtacagga agtagactaa
     6661 aacttttaaa agttttaagt ctatctattt ggcaagttta aaaaataaaa attcggtatc
     6721 aaaaaactgt taccgataac atttttgaaa gcgttgtctt ttgcttctct atcacttata
     6781 gtgatgacgt catattaaaa cacaaggagg aaatcaatgg atacagctgc aatttatcat
     6841 cgaccggaaa gtgaatatgc atttctatat acgaatacaa gatttcgtat tcggcttcgt
     6901 actaggaaaa atgatatcaa aaaagtatat gtgctatgtg gagatccata taccataaca
     6961 actgaaaaat ggtatcaaaa acaacgacca atgaaaaaat gtctaagtac caatgttcat
     7021 gattattggg aaattgaagt gacgagcgaa acaagtcgct tacagtatgc gttccatgtt
     7081 gttggggaag ataacacgga ctgtttttac ggtgatcaag gaatttttcc ttatcgagaa
     7141 aatgtgatta ctgaaccaaa tttttatttt cgaatacctt attttcatca aatcgatcga
     7201 ttcactattc cagaatgggt aaaagaaaca gtatggtatc aaatttttcc cgaaagattt
     7261 gcaaacgggg acaaagcaaa tgaccccgaa cacactttac cttggggaag taaagatcca
     7321 gaccgagaag actttttcgg gggagatttg caaggtgtga tggatcattt ggattacttg
     7381 acggaccttg gcatcaatgg catctatttt tgtcccatat ttaaagccac atccaatcat
     7441 aaatacgata cgattgatta ttatgaggtg gatcccgctt ttggcgataa aaaactttta
     7501 aaaaacttga ttgatgaagc acataaaaga gggatacgta tcatgttcga tgctgtattc
     7561 aatcatatgg gtgtccattc accacagtgg caagacgttc tcaaaaacgg agaaaaatcg
     7621 atctataaag actggttcca catccgtttt ttcccagtag attcttatca gatgactgac
     7681 ttaccagaaa ctgctgaaaa tatcccatat gatacttttg cttttactcc attcatgccg
     7741 aaactaaata cagcaaatcc agaagtgcaa aaatatttgc tggatatcgc aacttattgg
     7801 ataaaagaat tcgatattga tggatggcgt cttgatgttg ctaatgaagt cgatcatcat
     7861 ttttggaaaa aattcagaga agcagttaca gaaatcaaac cagacatcta tatccttgga
     7921 gagatttggc attcctctca agcttggctg caaggggatg aattccatgc agtgatgaat
     7981 tatgcattta cagattcgat taaagattat tttgcaaaaa agaaaatcac agcttcacaa
     8041 atggtcagtg gaatgaatca tcagcaaatg ctttacagag atcaggtgaa cgaaggaaca
     8101 ttcaacttat tagattctca tgatactgcc aggatcttga ccctttgcca aggtaacaaa
     8161 gaattgatga agtctgtgat ggcctttatg tttcttcaaa aagggtctcc ttgtatctat
     8221 tacgggacag aaatagggat gactggtgaa gatgacccgg attgccgcaa atgtatgata
     8281 tgggagaagg aggaacaaga tctagagcta ttcggtttta taaaagaact tgtttctcta
     8341 aggaaacagt tgtctaagat tatttctgaa ggttctactc agtggctaat agtaaatgat
     8401 cgtgaagata agctctattt cacacggaaa ctagagggac agatcatcta tgtttacttt
     8461 aatcagtcaa aagaaccttg ggtagtagaa caggaaaatg aggtgattct tagtcaaaat
     8521 tgtcagttgt tagaagacgg gaaagcagag atacgacaat acggattttt gatcatgtgt
     8581 tgaaaactgt taccggtaac aacaagaaag cgtttgcaaa tgaagatttg tgcccattat
     8641 aataagggtg taacagcacg ttgaatacaa aggaggaaat gaagatgaaa aaaagaagtg
     8701 tgaaacagtt gggtttaggg ttaatctctt taggaatctt aggcggatta gcggcttgtg
     8761 gcaatggtaa ctcttcagca gaaggggaag ccgatgaagg aaaaacgtta acagtttccg
     8821 ttgattctgg atataaagat tatataaacg aaataaaaaa cactttcgaa aaagaaaacg
     8881 atgtgaaaat caagctagta gaaaaggaca tgttcgatca gttggaatca ttagcgttag
     8941 atgggcctgc tggaaaggga cctgacgtta tgatggcagc atatgaccgg atcggtgcgt
     9001 taggacagca aggacatctg gcggaagtaa aactgggaaa tgaagcagct tacgatgaaa
     9061 cagacaaagc ccaagtgact tatgatggaa aaatctacgg agaacctgca gtaatcgaga
     9121 cccttgtttt gtactataac aaagatttag tcgatacagc accatcaacg tttaaagatt
     9181 tggagaatct atccaaagac agtcgttttg cttttgagtc agaagcagga aaaaatacag
     9241 gatttttagc taaatggact gacttttatt attcctatgg tttaattgca ggttacggtg
     9301 gctatgtatt tggtgatgat ggcacaaatc cttcagatat cggtttgaat aatgcaggtg
     9361 ctgtagaagg aatctcttat gcaacagatt ggttcaaaaa tgtttggcca aagggaatgc
     9421 aagacataaa aagtgcagga gacttcgcca gccagcaatt catgtccaat aaaactgcag
     9481 caatcattga cggtccatgg caagcgcaaa catacaaaga aaacaatatc aattatggtg
     9541 tagccaaaat tcctactcta aataatggac agccttatca accgtttggc ggaggaaaag
     9601 gatgggtagt cagcaattat gctaaaaaca aagacctctc tcaaaaatgg cttgattatg
     9661 taacgaatca ggaaaatcaa gaaaaattct ttgaaatggt aaatgaaatc cctgcaaacc
     9721 aacaagctag ggaaacagca aaggctaaaa acgatgaatt aacaacagct gtgattgaac
     9781 aatatgaaac agctcaagcg atgccaaaca tcccagaaat gggcgaagtt tggacaggtg
     9841 cagaaaactt gatgttcgat gcagcatcag gttcaaaaac accaaaagaa tccgcagatg
     9901 aagcagtaaa aacaatcagt gaagccatag aacaaaaata ctgattaaaa tgataaccgt
     9961 ccatttttat aaaaaatgga acaggtgctt cagataaaag tggcaagagc gagatggaaa
    10021 attatcttgc tcttgttgcc attatcttaa aagcagtttg cggtttagca agtttagagg
    10081 gggcattcag atgcagcaag ataaaacaag caatatcaac gaaaaaaaaa tcacgctttg
    10141 ttcacttatt ccagggatgg ggcagtttgt aaatggccaa gcttttaaag gtatcgtttt
    10201 tttcgccata ttcgtcctat tcattggtca gatgcttctg ggcggatttc atgcattggt
    10261 aggattggtt actttgggaa gtataccaat ggaagatcat tcattattta ttttgattga
    10321 aggcactttg caattcatca ttacaatcat tttcttgatt ttttacggtt tgaatctttt
    10381 agacgcttat cgagtagcga agatgcgtca agagggcaaa aaaatcaatc ggacgatgaa
    10441 ggaagtcata cataatatag gtgatgaagg ttttccttat ctattgacac ttcccgctta
    10501 tcttctcatg atttttacga tcattttccc agtcctagtt acattgttca ctgcatttac
    10561 taattatgac ttcaatcata ttccaccagc cagtttaatt gattgggtag gggctaaaaa
    10621 cttttttagt atcttctttt taagctcata tcgtaatact ttttttgcag tcttttcgtg
    10681 gaccgtgatt tggactttat gtgcaacaac tttgcaaatc acccttggta ttctcacagc
    10741 ggttgttgct caccagaaat ttattaaatt caaacgtatt ttcggtatca ttttcttatt
    10801 accatgggcg gtcccagctt ttattactat catgagtttt tcgaatatat tcaacgatag
    10861 cgtaggtgcc atcaatactc aagtgattcc tttcataaac cagcttcctt ttgtagatat
    10921 cagtgcaatc tcttggaaaa cggacccgaa ctggacgaaa gtagcaatta tcttagtgca
    10981 gggctggtta ggatttccct atatctatgt gatggttaca ggaatcttac aatcgatttc
    11041 agaagactta tatgaagcag caaaaatcga cggagcaaat gcatggcagc gcttttcaaa
    11101 catcacgctt cctgctgtct tcctagtggc agcgccaaca tttattacac agtatacggg
    11161 gaatttcaat aatttctcca tgatctatct gtttaacaat ggcggtcccg gaagcgtagg
    11221 cggaggagct ggttctactg atattcttat ttcctggatc tataaactta cgactggaac
    11281 ttctccgcag tattctatgg cttcagcaat cacgttgatt atctccgtca tcgttatctg
    11341 tgtgtcattg ctggtattta aaaagacaaa tgcgttcaat atgggggatt aacaatgaaa
    11401 aaatttcatt cgagtgctcg attccaaaaa cgactttctc acttttttac ttactttttt
    11461 cttttaatac tgtcagtcat tatcatctat ccgcttttga tcacagcaag tactgccttc
    11521 aagtcaggaa atattgcagc ttttagttta gatctttcaa gtgactggac tttaggaaac
    11581 tttactcggc tattcagtga aacactttac gggacttggt ataaaaatac attgatcatt
    11641 tctgtcctaa caatgatcgt acaagtgact gtagtaactt tggcgggcta tacttatagt
    11701 cgctatcgtt ttatcggccg caaatcaagt ttgatgttct ttttagtgat tcagatggta
    11761 ccgactatgg cagcattgac tgccttttat gtcatggctt tcttattaga agcgctcgat
    11821 aagtactggt tcttgacaat gatctatata ggcggtggaa ttccaatgaa tacttggctg
    11881 atgaaaggat actttgacac tgtaccaata gatttagatg aatctgctaa acttgatggg
    11941 gcagggcatt tcaggatttt tttccagatt gtattaccgc ttgtcaaacc gatgctcgcc
    12001 gttcaagcat tatgggcttt tatgggacct tttggggatt tcatgttagc taagttcctg
    12061 cttcgaacac ctgaaaatca gactgttgct gtcggcttac aaacatttat ttctgatgtg
    12121 acaaaccaaa gagtctctct ttttgctgct ggggcaattt tgattgcact accgatttgt
    12181 ctattattct tctttttaca aaagaacttt gttaccggcc tgacatctgg cggaacaaaa
    12241 ggataggagc agagtatcat gcaaacattt ccgttaaact atttttccgc attacgtacg
    12301 ccaactcaag tgtttgcggg acgcaaacta ttatcatggc ctaaattttt cttgatattt
    12361 gtatttttag tttccttgat ggtcatgcct gtgactcttt tttatgccaa tcagatccaa
    12421 gcgattccat tagaacaatt tctatccgtt cattcgctga tcgatgaaca aggaacccaa
    12481 aaattttctg aacttgaatt atctgaaact gggttacaag catcgcaaca aacgatagct
    12541 gtgacccctg aaattttggt aggtgtgtct ttatctgaga aacaacaatc cgatcatgga
    12601 acttttattg attttgagaa ggaacaatgg gtgatccaac aaaaggataa atctggtata
    12661 cgccgctata cgatgaatta tagcccatct ttccaaccag attctgtacg tacgcccgaa
    12721 gatttccaac gatttttaga aagagaattt tatgccagta atcgtccaac aatcatttta
    12781 tcttatagtt taagtcttgg tcttgtccta tttgtcatga cgagtctcat tttattcggg
    12841 gcttcctttt tcttgtggat gacaagaaaa agccaacttt catccattca tacattcaaa
    12901 gagagtgcaa atttgatgct gaatgttatg ggaataggtt ccatggcagc agcagttgta
    12961 gggtttatcc actttgactt tatcttgatg ctaagtgtcc aaacaacgat aactgtcttg
    13021 ctgcttttat gggtttttgt caaaacaaga ttcaaagata agcgtgtcga atgacaagtt
    13081 taagcgattt atgcgacaat gaatgtgaaa aaaatgaaaa ataaagtagt ttttgaaaaa
    13141 tttctgaaaa aattaaactt cttagttgat tcttttcttt tttagtatta acgtaatagg
    13201 gtagtttttt taaggaggaa aatcatgtta gagaaaactt tatacaatca attattttca
    13261 cgttctttct cgctccctgt cgaagtaaat tattgggacg gtacaacgaa acaatacgga
    13321 gatacggaca ctcctcccca aatcaaaatc aatatccatg aagaaatccc aatgaaagag
    13381 attacaagta acgcatcttt ggcactagga gaagcctata tggatcatcg aatcgagatc
    13441 gagggaagta tccaagcatt gatcaacgat gcttatcagc aagcaaacag ctttttacga
    13501 ggaaaagatt atctaaaatg gctgccaaag aaagaaaaac atacgaaaca aaaaaacaaa
    13561 gaagatatcc atgcgcatta tgacttaggt aacgactttt ataaactttg gctagatcca
    13621 actttgactt attcttgtgc ttatttcaat acacctgaag atacgttgga acaagcacaa
    13681 atcaataaag tccatcatat cttagacaaa ctctttatca aagaaggcga aacgttgctt
    13741 gatatcggtt gtggctgggg aacattgatg ttcactgcta ccaaagagta taatgtcaag
    13801 gcaactggga tcacactaag tgaagaacaa tacgatttga ttaccaaaag aataaaagaa
    13861 gaacatttag aagataaatg ccgtgtatta ttaatggatt accgcgaact aaaaggcgaa
    13921 acgtttgatc atatcacaag tgtaggtatg ttcgaacatg taggttctga aaatcttgaa
    13981 ggttatttca aagtggtaaa agatttattg aaaccaaaag gaacagcttt gatccatgga
    14041 atcagccgac aacaaggcgg tgcgacaaat gcttggatca ataaatatat tttccctggc
    14101 ggttatgtcc ctggtgttac tgaattagtt gataatatta caaaaaacga tttgcaactg
    14161 attgatttgg aaagcttacg tcgtgactac caattgacat tagaacattg gacaaagaat
    14221 tttcatcaag tccaagatca agtcacgaaa gaaatgggtg attccttcta tcgaatgtgg
    14281 gatctatatt tacaagcttg tgcagcttca tttgaatcaa gtaatatcga tgtgattcaa
    14341 tatttgcttg ttcaacctgg aaacaatgac atcccaatgc atcgtgcata attgaggcaa
    14401 aagtactgtt taaagactat ttaaaaagaa gctaagtttt atgatgctcc agaagtgaac
    14461 ttttttgtct aacttctagg attgtctcta aagcttagtt tctttttctt tatattttca
    14521 taataaaagt ttggttcttt aatttttaaa catgacagaa aattttttct tcgttatact
    14581 tgtaatagaa tactatttta taacaaaggg gatcgaatca atgaaaaaaa ctgttattta
    14641 tactagttta tttgcagctt tgtttttagc tgcttgtcaa tcaaatacca atcaaggcac
    14701 atctgggaat acgtcttcca gtagcgaaca gcgctcttca caggtatcgg actcctcaac
    14761 aaaagcaagc acatcttcgt ctagccagac aaaaagttct agtgaagcaa gtactcagtc
    14821 agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc caagataaat acccagatac
    14881 tgcaattact agtttggaat tagatagtga ttggggatct tacttctaca agatagaagg
    14941 tgtcgatgat caaaaagaat acgaagcaag aattgatgct caaaatgaaa aaatggagac
    15001 agagaatcca gaaactctag atcgagatga acaaaatggt caaaagaaaa aagaagatgg
    15061 tctggatgtt gataaattga tcacgattga ggaagcagca aaaatcgccg tcgacaaagt
    15121 aggaagcggt acggcaacag attgggattt ggataaagat ttaggtacta cttattggga
    15181 agtcaaagta aaagacggca atcaaagtac atcagtcaag atcaatagcc aaacaggcga
    15241 agtactgtca actgaacaag atgattaaga atttcttcgg aaaacaagag ttgatttttc
    15301 ttttagtcat gatacactag acaaaataac ttgtttgaag gagcgattta cttgagttta
    15361 gaaacgacct ttgccaatca tatctttgcc aatcctttga tgaatgcatc tggtgtccac
    15421 tgcatgacta cccaggaatt agatgaactg gctcattcag aagcaggagc atttatcact
    15481 aagagctgta cgatcaatga acgaaaagga aatcccgaac cacgctattt tgatgttcct
    15541 ttagggagta tcaattctat gggacttcca aacttaggtt tttcttatta tctagagtat
    15601 gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac cgttattttt ttccattgcc
    15661 gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa tagaaaaaag tgggtttaat
    15721 gggatcactg aattaaattt atcttgtccc aatgtgcctg gaaaaccaca actagcttac
    15781 gattttgagg ccacttatga aacactgaaa gaagtattca gcatcttttc taagccgcta
    15841 ggaatcaaat tgcctcctta ttttgatttt gctcattttg atcagatggc tgatatcttg
    15901 aatcagtttc cattgaccta tgtcaatgct atcaacagtg tgggcaatgg tttgtatatc
    15961 gatacagaac aagaagcagt agtcatcaaa ccaaaagaag ggttcggcgg cattggcgga
    16021 gagtatatca agccgactgc tttggcgaat gttcgcgctt tttatacacg tttgaaacca
    16081 gaaatccaaa tcattggtac aggtgggatt cggacaggac aagatgcatt tgaacatctg
    16141 ctatgtggcg caagcatgtt acagattggt accgagcttc ataaagaagg gccggaaatt
    16201 ttttctagaa tcataaaaga attaacgcag attatgtcag aaaaaggata tacgtcaatt
    16261 gacgaattta aaggcaaatt acgcaccatt tcatagcaaa gagacgaagg tcatgattga
    16321 tcttcgtctt tttttataaa aaacactcgt ctgttcattc ctgtgcaagc gtactcattg
    16381 tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa ggaggataat atgaatgatg
    16441 caacagaatt agcaaaagag cttaaagaaa aagaatttag ttttcaagaa ctagttacgg
    16501 atatacagaa aaaaataaag aagcaaaatc atgaattgaa tgcgtttgtc gcgcttgaac
    16561 cattcgagag taattcccac gagctattga ttccccagtc agaaaaaggg ccattggctg
    16621 gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa gggatggcta gctacttcag
    16681 gatctcgttt atttgaaaca caccgagctt ctcatacatc taattatgtg cggcaagcag
    16741 aagcgatagg tctagttcct tttggacaaa ccaatgcgcc agagtttggt ttcaaaaata
    16801 ttacagaccc agtcatctat ggcccagcaa gaaacccttg gaaccttgaa tgtacaccgg
    16861 gcggatcaag tggaggagct gctgctgcag tttcatcagg aatcgttcct ttagctggtg
    16921 ctagtgatgg cggtggttct attagaatac ccgcttcgtt ttgcggattg attgggctga
    16981 aaccttcgcg agggacgatg ccagttggtc catatgcttg gagaggatgg caaggagctg
    17041 ctattgattt cggcttgaca gtttctatga gagacacgga ggctttattt tatgggatga
    17101 gaagtatcca ttccggtgcg ccatatcaag tatcgccagt tgagtggcaa acacatccaa
    17161 gaaaaaaacg gttgaagata gctttttgtg ttgattcacc gatccactca cagattagtg
    17221 aagaggcagt acttgctgta aaaaaagctg tagatttcct tggaaaagaa gggcatgatt
    17281 tgacagagat tccttaccca ctagatggtc gtaaactgat cacgtcttat tatcagatga
    17341 atggcgcaga aacagcagca atgatccgct cgattgaaac aggcatccag cgagctgtca
    17401 gaaaagaaga acttgaaccc atttcttgga ctttgttcca atatggtcag aagctctctg
    17461 ccgctactta catcgattct ctgcatgtat gggatgaagc agcaattgtc atggaaaacc
    17521 tacatcaaga atacgatcta ttcctttcac caacgactgc atttaccgcc cctaaaatca
    17581 gcgaagattt gcaaagtgat gcgataagag cacagatgga acacatcagt gattgttctg
    17641 aagtagaagg tttagacgtt gtttcttcca tgtttgagga gagcttgaag atcacacctt
    17701 atacacagtt ggctaatctg actggacaac cagcaatcag cttgcctact catttgacaa
    17761 aagaaaacat gcctctagga atccaattta tggctgccag aggaagagaa gatttgctat
    17821 ttcaaatcgg ctatctattt gaagcaaatc atcagttcca tttaccaaat ccatggaaat
    17881 agcagaaaca aggagaagaa gaatgaagaa aaaaagattg tttgctctaa taactagtgc
    17941 cttttttatt ttaagcgctt gcggtacagc tgccgctaat caggaagata acagctggag
    18001 taatgtagaa aaaaagaaag aattagtagt agcgacttct ggcacactgt ttcccgcatc
    18061 ttattataat gatcaaaatg aattagttgg ttatgatgta gatttggcaa aagaggtggc
    18121 taaacggtta aatgtcaaaa tctcctttaa agaatacaac gtggatggac aaatcacttc
    18181 tgtttcaaaa agagaatcag attttgctgc gaacgatttt ggtatcacaa aagaaagaga
    18241 aaaaaaattc tccctttcag agactttcaa atattcattt gacagtatga tcgtacgaaa
    18301 aaaagatgat tcaggaatcc actcacttga agatcttaaa gggaaaaaag cagctggcga
    18361 acccaatact agctatatgc gtttagcgga aaaacacgga gctaaattag tcacatatga
    18421 caatgccacg aatgatcagt atttaagcga tgtagcaaat ggtcgaacag atgttattct
    18481 aaatgattat tatctgcaga aaatggccgt atctgcttta ccagatatcc ctgtaaaaat
    18541 actggagaac gtttatttca atgaaaacga aagtggtttt ttattgaaag aaggaaatga
    18601 tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg aaagaagatg ggacgacaaa
    18661 gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc aaaccgaaag aaacgatggc
    18721 tgagtcggtg agtgagtgat gtactttcct ctaattgatt tatccctcat gtggacttca
    18781 cttcctttcg tactgcaagg cttggtatac acattaggga ttggcttcgt gtcgtttctt
    18841 ttaggaaatc tggtagggtt gcttttgaca gttttaggtc ttttggattg gctgcctctg
    18901 aatgtattta ttcgttttta tttatcgttc tttagaggca ttcccgcact agtcctgctg
    18961 tttctgttat attttgggtt accttatcaa ttaagtgcct taacggcttc agtcatctgc
    19021 tttacgatta ccagcagtgc atttattggt gaaatctatc gaggatcact agcaggcgtt
    19081 tcttcaggtc agtgggacgc tggtttagct tctggttttt ctttctttgg ggtattgaaa
    19141 tatatcgttt tgccgcaagc ttttcgaatc tcagtaccgg cactcagtaa cgtagctatg
    19201 gatctagtga aaggtacttc gttagcagca acaatcacag tgccagaaat atttcaaaaa
    19261 gcaaagatca taggcggtcg gacattcgat tatttttctc tctatatttt agttgcactg
    19321 atttattggg tcatttgtat cgggatcgaa aaagtgcaac agtatttaga aaaacgttct
    19381 atgcatcagt caatctgaaa aatagaaatg gtgctagcgt ggctggcacc atttctattt
    19441 tttgtttctt gtatattctg cctagtattt taaaaccatt tcatgtaaaa tgtaaatcga
    19501 aaatatgttc ggaggtagaa aacatgaaga ccccgctaac catcgaaata gaatcctcgt
    19561 tataccaata ttgcatcgag caaggcggct tggttgtaga agaagtcacg atgcctgatg
    19621 accaaggaat tgtagatacg cttagctgct tgacaaaatt tgatggaagc cgagaatggc
    19681 gatgctatga gctgaaagtg acaaaagcag attttcgctc tacagccaaa ctgtcatttg
    19741 ttggacatta taattatttt gttttaccaa gtaaactata tgaagaagta aaaactgaaa
    19801 tccctacagg aataggtgtt ttagtgtatc gtccgtacac ggttgaagag gagatgcctg
    19861 cctctggtac atttctgatt gcgaaaaaag cagcaaagaa agagcttgct gtaccggaag
    19921 aagctttgac aaaccgcttc atggcttctt tattcaggga agtaagaaaa gcaaagcaaa
    19981 tggagcgagg cgtaaaatat tttccaacag atcaattgta caaagaattg aaaagacgtt
    20041 cagaaaatca agatccattt tctaacgaac gatattatga acggttttta gaggaaatag
    20101 ctagtcaggc aatcaatgag ttgcaagaag aagttatcgc gcttcagcat gattatgaat
    20161 atttgaggca acaacagcag atccgtcggt tgcctacaga gccattggag tgaaaaatat
    20221 gtactatcct tatttaagag gaaaacaatt tgacctatta gcattaaaag aagcactgtc
    20281 gcgaggattg ctctccaata aaatccaacc agtgatcgaa ccagtacgtg attccgctac
    20341 gcttaaaaat gtgatcgaat tatttcaaaa aaagcaccat cgaatcgctg tgatccaaaa
    20401 tccccaagta ggacaattca aattattcga tcagcatgtg cacagttgga cagtcaaaga
    20461 aaatagctct gtcgtccctg cacagatctt aacgccagaa aatctcagtg aagtactgga
    20521 ttcacctcca gcgtttcttg ttttcgatgg acagcactac ccaaaagata cagaggtgtg
    20581 gaaacagttg gcaggagttg attcgaaatt tttgatacca gatactagtc gctttcgcat
    20641 ctggctgccc gaaaacaaaa ttgtgatccg tgactctttt caaacgagaa agcatgttga
    20701 aagttatgca gataaaacag atgacttttt tagtgatgac tatctttttt tccacgcaga
    20761 cggatatatt ggattttctg atttcacgat cgaaggtagc cgttatttcg ataaagggtt
    20821 ccctagccga gcgcttgcta tccatctaac gtatattgat gcttacggca atatacgcgt
    20881 gaaacatttt gtctctgaca gtaacgactc tgctaaagac caagcattga agtttcttga
    20941 agcaggagat aaaatgaaaa aatggatcat gcgtcaccat catcaactct tgattacttc
    21001 aggaatgatt gaattattgg ctctttacca gcaacaaaaa ttccctggac tgggagtgtt
    21061 gaaaaagtgg tcacttatgc atcatttgga acttattagt cacctgctag atcatccaaa
    21121 agattggctt aaatattatt caaaagttca ggaactatat gaagtgatcc aatgattaga
    21181 taatgtaaat gaaaaaggaa tagaaaagag gaaactggat gtatattcgg caaacaagga
    21241 aagaagaagt agaagaagtg gtagaaatca ttaatgccgc agcggatttc attgcttcgc
    21301 aaggctctcc tcaatggcaa aacgggcaga aaccaacaaa agaaacgatt ttgaacgata
    21361 ttgaaagaaa agaaagctat gtattaatag tggaagatca aattgctgga acagctgcat
    21421 tagtctcaag cgtggatccc gtttacacaa aaatagatgg tagttggaaa gaatcaactg
    21481 gtccttattt atcgattcat cgtgtcgctt tagcagaaag tactcgagga aaaaaactag
    21541 caaaaccgtt cttagaacat ttgttgacga ttgcagccag caaaaatatc caagatatcc
    21601 gtatcgatac ttatccagct aatgaaccga tggaaaagac catctattct gctggattca
    21661 cttatcaagg gatgattgaa tttccttttg aacacggcga aagaaaagca tatcaaataa
    21721 tcatcaattg actataaaat catctgagca aagataaaga cattaacact actgaaaaaa
    21781 acaatcatat gatagccaag aggttgtaac agaagtggcc agcttcaaaa aacaagaaag
    21841 aatttccgaa aatgcttctc aaatttttgt ggaattttag cgtattttac gaaatagctg
    21901 ctttctgaaa ctcccttcat cgagaggtcg tgacatagct tttgtcacga cctctcggct
    21961 tatcctacga gtattattcg atacatttat atcaataatc ctttttttat tttatctgca
    22021 gcttcttgga acgctccatc gtttgacacg actaaaagtg aggggatagc tttcaaacgt
    22081 ttcaactgtg ctaaatcttc tacataaacc gccagtctgg ctgaaatctg ttcagatgaa
    22141 tctccacgtt ttttcaggcg cgattgcaat gtttctttag agatcgtaat aaagatagga
    22201 cggactaccg tcccgaaata ctcatataaa tgccaaaaac catttgctgt caaaacggcg
    22261 taacaatttc ctactgtcag tttcttttta atttctgctt tactggaacc atatttatgt
    22321 tgagcatatt ggtcccactc tgcaaactca tttcccttga tcatctgatt gaatgtattg
    22381 tcagaaacaa aataataatc ctcttgatct ttttccccag gtcttggtga tcgattcgtg
    22441 taagtaatga tcttttgttc cggctgaaaa atagcttctg cgagtgaagt ttttccagaa
    22501 ccagaaggac cgataaatac atagcaataa ttcattgtca tttctccttt gatgattgaa
    22561 caagtgaaaa agctttggaa aatatttcca aagcttttaa aagtaacttt gcttttttgt
    22621 atattatacc agcaagccag tcacaatagc acttaaaaag ctgactaaag tcgctgttag
    22681 caaaattttc aatccgtgtt ttgcgacaag atttcctttt tcttcattta atcccttcat
    22741 cgcaccagaa atgatcccga tagaagagaa gttggcaaat gaaacgagga agacagatat
    22801 aattgctgtt gtacgctcag taaaatggaa attaccattt gctaattctg tcatagcaac
    22861 aaattcattt gtaaccagtt tagtcgccat gatactaccg gcatccactg cttctttcca
    22921 tgggattccg ctgatgaagg caagaggggc aaagatgtaa cctaggatct cttggaaagt
    22981 gatgccgaat atcccgtgga agatagcatt gatcatggca atcaaagcaa caaaaccgat
    23041 aagcatagca gcaaccgtga tcgccacatg gaaaccatca agaatgtatt ctcccaacat
    23101 ttggaaaaat gtctgttctt tgttttcttc aatgatcagc tcatcttctt tttcttctaa
    23161 tacataggga tttacaattg aagccagaat ataaccgcca aataagttca aaacaagggc
    23221 agtgatcaca tatttagaat cgatcagtgc catataagat ccgacgatcg acatagaaac
    23281 tgtagacata gccgatacac tcatggtgaa caaacgtttc tcagatagga agggtaattc
    23341 cttttttatg gaaataaaaa cttccgattg tcctaaaata gcagaagcta ctccattata
    23401 agattccaat ttgcccatcc cgttgatttt acttaatcct agaccaacag ctttcataaa
    23461 taatggaaga atcttgatat agcgtagaat accgataata gcagaaataa atacaattgg
    23521 catcaatacg gaaagaaaga aaggtgcact tcctttattt gctacaccgg caaaaacaaa
    23581 gtcaacacct tgcccagcaa aagcaagaag atgatcaaac atttttgcca atacagaaac
    23641 aaccgctgta ccaaaagttg tacgtaataa tacgaaacca agaacaagct gtaaaacgaa
    23701 catcacaatt agtggtttca atttgattgc ttttttgtta ctgctgatca aaaaagcaag
    23761 ccctaatgtg acaaataaac caataatacc
//
LOCUS       DAFKHN010000042        23592 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFKHN010000042 DAFKHN010000000
VERSION     DAFKHN010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.042"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="LY912_001648"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="LY912_001648"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBM6955333.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="LY912_001649"
     CDS             complement(1172..1867)
                     /locus_tag="LY912_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBM6955334.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="LY912_001650"
     CDS             complement(1880..2596)
                     /locus_tag="LY912_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBM6955335.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="LY912_001651"
     CDS             2926..3534
                     /locus_tag="LY912_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBM6955336.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="LY912_001652"
     CDS             3859..4182
                     /locus_tag="LY912_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBM6955337.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="LY912_001653"
     CDS             4364..5734
                     /locus_tag="LY912_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBM6955338.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="LY912_001654"
     CDS             complement(5864..7165)
                     /locus_tag="LY912_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBM6955339.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9477)
                     /locus_tag="LY912_001655"
     CDS             complement(7519..9477)
                     /locus_tag="LY912_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBM6955340.1"
                     /translation="MTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="LY912_001656"
     CDS             complement(9654..9920)
                     /locus_tag="LY912_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBM6955341.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="LY912_001657"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="LY912_001657"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBM6955342.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="LY912_001658"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="LY912_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBM6955343.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="LY912_001659"
     CDS             13264..13827
                     /locus_tag="LY912_001659"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBM6955344.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="LY912_001660"
     CDS             complement(14080..14601)
                     /locus_tag="LY912_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBM6955345.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="LY912_001661"
     CDS             complement(14604..15446)
                     /locus_tag="LY912_001661"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBM6955346.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="LY912_001662"
     CDS             complement(15439..16164)
                     /locus_tag="LY912_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBM6955347.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="LY912_001663"
     CDS             16340..16636
                     /locus_tag="LY912_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955348.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="LY912_001664"
     CDS             17204..18796
                     /locus_tag="LY912_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBM6955349.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="LY912_001665"
     CDS             18809..19549
                     /locus_tag="LY912_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBM6955350.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19717..21066
                     /locus_tag="LY912_001666"
     CDS             19717..21066
                     /locus_tag="LY912_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBM6955351.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21194..21784)
                     /locus_tag="LY912_001667"
     CDS             complement(21194..21784)
                     /locus_tag="LY912_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBM6955352.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21931..23283
                     /gene="brnQ"
                     /locus_tag="LY912_001668"
     CDS             21931..23283
                     /gene="brnQ"
                     /locus_tag="LY912_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBM6955353.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6744 a         4758 c         4498 g         7592 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagtcattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaaataaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgaaatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtatctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 atcaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acaaacttcc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgccatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 aacaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa aacagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagattact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaaaattttg gaatcttagt tgtgtttttc agaaaactct tttaatatgg
    19681 aagtaattaa acttttttag ttaggatgat ttaaaaatga atgaagagca agaactgcag
    19741 cgtggactga aaaatagaca tgtccaactg atttctattg gcggagcgat tggaacgggg
    19801 ttgtttttag gttccggaaa gtctatccag ctagctggcc cttcgatatt gctcgcctat
    19861 cttattactg gatgcatctg ttttttcatt atgcgtgcgt taggcgaact tctgttatca
    19921 aacaccaata accattcttt tctggatttt gttgcagaat atcttggcaa aaaagcggct
    19981 ttcatcactg gctggacgta ttggttctgc tgggtatcga ttgcaatggc cgatttaaca
    20041 gccatcggaa tgtatgtacg ctactgggcg cctggtgttc ctcagtggct tcctgaactg
    20101 attgcattag gtcttcttct ttgcttgaat atggtggctg tctcattgtt tggtgagtta
    20161 gagttttggt ttgcattgat caaagttgta gcgatcattg cctttatcct cgtaggagct
    20221 tatatgatcc tcacccacta tacgacagat attggcacag ccagtatcac gaatctatgg
    20281 tctcatggcg gattctttcc aactggtgca aaaggattta tcttagcttt ccaaatggta
    20341 acctttgctt ttgctgggat agaattagtt ggattagtcg ctggagaaac agaaaatcct
    20401 gaaaaagtgt tgccggaagc tatcaataat attcctatca ggatcatctt attttactta
    20461 ggatctcttt ttgtcattat ggcaatctat ccatggaaca gcttgaatcc agataacagt
    20521 ccatttgtag aagtattttc ggaaattggg atcacgattg ctgcttcctt gatcaattta
    20581 gtcgtattaa gtgcagcagc ttctgcctgc aacagtgcaa tatatagtac aggacgtatg
    20641 cttcgttctt tagcgcaaga aggcagtgcc cctaaaaaat tcaaaaagtt aacaacacat
    20701 catgtgccag ggaatgcttt gacattttct actatcgtca ttttcatttc tgttatcttg
    20761 aattacgtga tgcctagtga agtattcaca ctagtaagca gtattgccac tacttgtttc
    20821 ttgtttatct ggagtatgct tgtctacacg cacatgaaat atcgtaaaag tatcctcggc
    20881 aaaaaagctc attcatttaa aatgccgttg tacccattta gtaattatct ggtatttctt
    20941 tacatggcct ttgtgtgtgt cgtcttgttc ctaggaaaag atacgagaat cgctttatta
    21001 ctaacacctg tgtggttctt gcttctatta ctaatctatc atatgaaata tgaacgtaag
    21061 aagtaagaaa gtagttgtga cagaagtggt cagcttcgag aaataagaag gaatttacga
    21121 aaattgcttc ttaaattttt gtgaaatttc ggcttatttc ttggagttaa aagcttctgt
    21181 cccagcctct tttctatttc cccggaaaca accgctgata ataggcatct gcttttttat
    21241 aggaaaaaat ccaaatacca gatacaaaaa aacgtccgaa taacccgatc aacggtacaa
    21301 aaaagacacc ggcaatcaag cataagttaa tcatcatgga gataagactt cgacggtcct
    21361 ttgacaaaac tctcacgaca tgggaatctg gtttatttgc tttcatgatt tgcctcatca
    21421 agataccaaa agaaaaactc cacatcgtgt atactaagac ataagccatc tcaggccaaa
    21481 aagcttcagg gttacgcccg acccaactag taacagaagg acataaagtc agccaaaaga
    21541 gcaaaaagat attcgaccag accactcggt aattaattcg ttctgccatc tgaaatatac
    21601 gatgatggtt cacccagatc accgcaacaa atataaagct gatggtataa gctaataatg
    21661 tatttcggat gacccataaa gaatgaaagc tagatgtatt agggatcttg atctctaata
    21721 caagaactct caaaacaatg gctaccactc catcagtaaa tgcttctaat ctcgactttg
    21781 tcacgatgat tcctcctcag atgattcagc gcttttattt tatcacttac gttattaaat
    21841 aaccgtcgtt ttatatagga aattttctga aaattgttgc atatttttcg aaattttgtt
    21901 acttttaaaa aaaccgtaaa ggagttatgt atgacaaaaa aattatcatt taaagactat
    21961 ctttttatag gctccatgct tttcggtcta ttttttggtg ctggaaatct tatctttccc
    22021 gttcatttgg gtcaagaagc aggcgctgct accttttggg cgaatctagg tttcttggtt
    22081 accggtatcg gtcttccctt cttaggggtg attgccattg gtgtatcgaa aagctcaggt
    22141 gtatatgaat tagcaaaacg gataaatcaa acatatgcga tggtttttac catcttgctt
    22201 tacttagtta tcggaccgtt ttttgcttta cctcgccttg caaccacatc tttcgagatt
    22261 ggtttagcac catttatcga tcctagcaga cagacgctat atctagcaat tttcagtatt
    22321 gtattttttg tgctggcttg gtggttttca agaaaaccga caaagatatt agattatgtt
    22381 ggaaagttcc tgaatcctgc atttttggtt ttattaggtg ctttgcttct ccttgctttt
    22441 ttgaatccac taggttctgt aaatcaagcg cctattcagc caaattatca agagcatgct
    22501 tttttcacag ggtttactca aggatataac acattagatg cgcttgctgc tttagcattt
    22561 gggatcatca ttgtcacaac aatccaaaac atgggtgtaa caaaacctgc tgaaatcgct
    22621 aaagacacga tcaaatctgg tgcgatcagc attatattga tgggaatcat ttatactttg
    22681 ctcgcttatt taggtgctat gagcttaggt agctttgctc taagtgaaaa tggcgggatc
    22741 acgctggctc agattgctga tcattattta ggtacttatg gcagtatctt attagcattt
    22801 atcgttatat tagcttgctt gaagaccggt attggtttga ttacagcttt tgcagaaaca
    22861 ttcacagatt tgtttccgca aagaaattac gcattctttg ttgcacttgc tagtatcctt
    22921 ccttgtttag cggcaaacgt aggcttgacg aatatcattc aattttcgtt gcctgttttg
    22981 atgttcatct atccattagc aatgacactg attttactag tgttagttgg tcctttgttt
    23041 aagcagcgta cggctgttta tcgaatgact acttatttta cattgattgc ttcgattttt
    23101 gatgggttga acgcttgccc agaaactatc aaacaaacac ctattgttca aaatctttta
    23161 tatgttgcgg aaagctactt gccgtttttc aaattgggga tggggtggat cgtaccagca
    23221 gttatcggtt ttgttatcgg actgatttgg agtttcgcta agaaagaaga agtagcagat
    23281 tgataaaaga ggttgtgaaa gagacgttca gccttattgc cgataggctg tctcttgaac
    23341 actgtttatt gagaggtcgt gaaaaagccg ctcagtttcg agtattaaga aatatttttt
    23401 gaaaatggct tctcacattt ttgcataaat ttgacttaat accgagaaac tggcttttga
    23461 acaccgttta ttgagcgtct ataaactgac ctgagtatta gagaaacaaa acggcaaagt
    23521 agctccatat actttgccgt tttgttttga actaataccg aagagaagct gatcaaacaa
    23581 catttctttt at
//
LOCUS       DAFKHN010000043        23523 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFKHN010000043 DAFKHN010000000
VERSION     DAFKHN010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.043"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            150..557
                     /locus_tag="LY912_001669"
     CDS             150..557
                     /locus_tag="LY912_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955354.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            571..972
                     /locus_tag="LY912_001670"
     CDS             571..972
                     /locus_tag="LY912_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955355.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            974..1345
                     /locus_tag="LY912_001671"
     CDS             974..1345
                     /locus_tag="LY912_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955356.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1381..1683)
                     /locus_tag="LY912_001672"
     CDS             complement(1381..1683)
                     /locus_tag="LY912_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955357.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1932..2132)
                     /locus_tag="LY912_001673"
     CDS             complement(1932..2132)
                     /locus_tag="LY912_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBM6955358.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(2437..3669)
                     /locus_tag="LY912_001674"
     CDS             complement(2437..3669)
                     /locus_tag="LY912_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBM6955359.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            3923..4492
                     /locus_tag="LY912_001675"
     CDS             3923..4492
                     /locus_tag="LY912_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6955360.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4670..5110)
                     /locus_tag="LY912_001676"
     CDS             complement(4670..5110)
                     /locus_tag="LY912_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBM6955361.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5268..6032
                     /gene="map"
                     /locus_tag="LY912_001677"
     CDS             5268..6032
                     /gene="map"
                     /locus_tag="LY912_001677"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBM6955362.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6064..6987
                     /locus_tag="LY912_001678"
     CDS             6064..6987
                     /locus_tag="LY912_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBM6955363.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7063..8202
                     /locus_tag="LY912_001679"
     CDS             7063..8202
                     /locus_tag="LY912_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBM6955364.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8195..8995
                     /locus_tag="LY912_001680"
     CDS             8195..8995
                     /locus_tag="LY912_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBM6955365.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            8995..9822
                     /locus_tag="LY912_001681"
     CDS             8995..9822
                     /locus_tag="LY912_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBM6955366.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9800..10534
                     /locus_tag="LY912_001682"
     CDS             9800..10534
                     /locus_tag="LY912_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBM6955367.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            10634..11500
                     /gene="rfbA"
                     /locus_tag="LY912_001683"
     CDS             10634..11500
                     /gene="rfbA"
                     /locus_tag="LY912_001683"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBM6955368.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11514..12086
                     /gene="rfbC"
                     /locus_tag="LY912_001684"
     CDS             11514..12086
                     /gene="rfbC"
                     /locus_tag="LY912_001684"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBM6955369.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12108..13136
                     /gene="rfbB"
                     /locus_tag="LY912_001685"
     CDS             12108..13136
                     /gene="rfbB"
                     /locus_tag="LY912_001685"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBM6955370.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13234..14085
                     /gene="rfbD"
                     /locus_tag="LY912_001686"
     CDS             13234..14085
                     /gene="rfbD"
                     /locus_tag="LY912_001686"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBM6955371.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14120..16153
                     /locus_tag="LY912_001687"
     CDS             14120..16153
                     /locus_tag="LY912_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955372.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16197..17477
                     /locus_tag="LY912_001688"
     CDS             16197..17477
                     /locus_tag="LY912_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBM6955373.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17687..18493
                     /locus_tag="LY912_001689"
     CDS             17687..18493
                     /locus_tag="LY912_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955374.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18505..19725
                     /locus_tag="LY912_001690"
     CDS             18505..19725
                     /locus_tag="LY912_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955375.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19715..21301
                     /locus_tag="LY912_001691"
     CDS             19715..21301
                     /locus_tag="LY912_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBM6955376.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21340..23478
                     /locus_tag="LY912_001692"
     CDS             21340..23478
                     /locus_tag="LY912_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBM6955377.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALKMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7518 a         3928 c         4825 g         7252 t
ORIGIN      
        1 cagatatgct tacaaatata cttataaata tgcttacaaa attagctaat atttccgttg
       61 acaaagcttt gttactattg ttaaactaaa ttgactagca aaagtgaaac ataaatttat
      121 taaataaatg taaaaattag gagaaatcaa tgtcttatag agtacaatta ataatttcag
      181 aagatgtaga aagtcagcaa tttggcacta atgttattaa taaagtaatt aatccagctc
      241 tttctattaa tgcgccttta attcctactg ctttatcatt ttctgtaaca gctgtggtgt
      301 ctgagataga ggatacagaa aagataaaaa tagtagaaat tgaagtttta aacaagaatg
      361 aaaaacaaat tttttctacg ggtgaagtat cggtaagctt gcctcctcaa gttaacgata
      421 taaactttaa tataaacgcc agaaatgtct tggttgaaga agcaggagag cattatgctg
      481 ttgttaaatt taatggaact gagattggaa ggcaaatctt tgatatcaag gtcaacaaac
      541 cagtggaaaa aaattaagga gacgatacgg atgcttgata tagtaccatc aaatacacat
      601 cggagtggta gcttaataaa ttttgctgcg atttttgctt gcgcatcggt aattctagca
      661 tctccagttg ttgtggatgc aagttctact ccgaaaacta aaaatgataa tcaacttgta
      721 attactacaa aaaatgagat taacacaatt tcaagtaatg atggcaaaat ttttgatgtg
      781 ataaatacgg ttttaaaaag aaaagctgaa atcaatataa aatatgatga agatttaaac
      841 ttgtatttct ttgttatcaa aacaacatct gaattgtttt cctcagatta cgatgttttg
      901 gatactctcg ataatgtatt atctgactat aaatatatgg ggaaatctgt agtagcaact
      961 ttgggggaat aaaatgtttg actttaatga atatttatct atttccaaac aaattgaatc
     1021 agatgataaa tataattcta aagaatctta tagaagaact gctgtttcaa gagcatacta
     1081 cagtgctttt aaaaaatctg atgagtattt gaaagaaaat tatgatatta tttataatgg
     1141 aagtagcgga aaaggaagcc accaaaccgt ttggaatttg ttttcaacag ttaaggaatt
     1201 gaatacctta ggaatacata atagtgggta tagaatgtta gagaaaagaa aatgtgctga
     1261 ctatattcct aatgaaacca ttacgaaaac agatatggcg ctgatgaatc gagaagcaga
     1321 aaaaataata aacaaactca cctaatgaat ttcaagcgag tttgtttgtt atttttttat
     1381 ttaatctttg tatctttctg gatcaacgaa agtatacttt atatagtcat aacgccgatg
     1441 atcgctacgt gcgtccggca cgtcagtcac gatatcaaac aaaaagtata cacccttctt
     1501 cattctagtt ttcgcagcag gaattttgaa atagttctta ttagaatagt agagattgat
     1561 taataagcta tcttcgattg ctaaaaagaa aacttctgaa ttccatactt tataaaaatc
     1621 tttgataaat ctattcgaag ggtcaaattt aaaccataat tgtgtttttc cttccatcag
     1681 cataaaagtt cacctcaaaa agagtatacg aacgaatgtt ctttttgtga aggcggaatt
     1741 taatatactg aataatagaa aacaagtact tgtgccaaat tatgtgccaa aaaaattcga
     1801 attcaacaaa atgtaaacaa atagaaaacc ttctatatta agatttcctg caataacaaa
     1861 cacaacagaa gacgtgtaat agttagtcag gaacgtacaa ataacccctg tatcctttgc
     1921 ggtacagggg gttattttgt ataagtagac attgtagttt ctaaactgct atgtcctaaa
     1981 cgtttcgata cgctaagtat atttactcct tgataaagta aaatagatgc atgcgtatgt
     2041 cttagtccat caataaacag tcgaagagaa aatagggaaa aattgattac taaagaaaaa
     2101 cttactaggt cgacggtgta gttgattttc atacttcaat agattcgaat taaacgattt
     2161 cgattggctt ataccagtcc tatccaacga aagatatatc gttcttaact ctagcggtat
     2221 aacttgaagc tttacgtaaa gccaatggga atgaactgga gatgactttt tattattttt
     2281 agtaatagct gatgggttaa tacttacaac tttccttttc aaagtaccat ataaaaaaac
     2341 ggtggggttg tttagcgaaa taaaggatct aagccaatag cttagatcct ttattctatg
     2401 ctttatatta ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa
     2461 aatcggtact gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac
     2521 catgaaatct acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga
     2581 catttctgta ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga
     2641 tgcgttttca tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg
     2701 gtcaggtaca agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt
     2761 tgctaagaca tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt
     2821 aaatttcata cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta
     2881 accatctact cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat
     2941 gaatttttct ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa
     3001 tccgataatg atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt
     3061 caattcttct gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc
     3121 ttcttcatag acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc
     3181 ttctggcagt tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt
     3241 ccaactgact ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc
     3301 tgattgataa gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga
     3361 aacaacgctg atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga
     3421 ttgtggtaca ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg
     3481 gtcgtcagtc cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat
     3541 caatcgagca aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc
     3601 tgtggctacg ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc
     3661 agataacata ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca
     3721 tttaattatg attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt
     3781 taagtttcat gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta
     3841 attttgcata tcaaaaaaac atgttacaat gaaattaatc aatggtggaa gcgttataaa
     3901 aaaattaagg agattaaaaa atatggcaag aaaaaagacg attactagag aacagatttt
     3961 ggcagctgct tatgaagtag ctgccaccga tggatttaca cgatttactg cgagaaacat
     4021 cgcgaacaaa atgaattgtt ccacgcaacc gatttatctt gagtttaaaa atatggatga
     4081 cttgagacaa gctctttttg agcagatcta tgatcattta caatatgaag tgttcactgt
     4141 tgagcataca gggaatacga ttatcgatct tgcttttaat tatatccatt ttgcaagaag
     4201 agagaagaag ttgtatcgtt cactgtactt agaagaatat ggtggaggaa aagagatgca
     4261 gaatttctct tatacttact ttgtgaatac agtgaaacgc gatccagctt atgtgaatct
     4321 ttcagaagag cagatcgaat ctttgtataa tgggacatgg atcatagcta ctgggatcgc
     4381 agctttgatg tcttcaagca tcatccatcc aactgatgaa cagattgaaa agatgatcca
     4441 agacagtata gatgctatct tgaaattcaa agaaccaatc gaaatcgatt gaatatactc
     4501 aaaagttcca caaatcagta ggtaacaaga gatgtgtcaa aataaggaaa agttcgtttt
     4561 tcttacagcg tatgcatttt taactcccga agaactcttc catgaatgca atgaataaaa
     4621 gagccataca gattgaataa atctggatgg ctcttttatt gcaagtatat taaatttttg
     4681 cgactagttc tttagcgaaa gcttctaaat tttcgatatc ttcttcttca gcattcagat
     4741 ccactttaac attttcggct ccttttgatg cgcctgtttt tgcaaaagca gcatcgaaat
     4801 catccaccga tttgcagaat tcatcgtaaa aagtatcacc agatccgcag acaccgtaaa
     4861 tttttcccaa tagatccaat tcttgcaagt cttcataaaa gtctacgatc tcatcaggca
     4921 gatcgccatc atcgtatgta taagtagcta ctacgcaaat atctgcctcc tcgaattcat
     4981 ctgcatctac ttgggtacat tcgttgattt cgacttcgat atccagattt tcaaatgctt
     5041 ctgcaacaat atcggcgatt tcttcagtgt ttcctgtcat gctagcatat acgatttttg
     5101 ctaaagccat gatgtgcctc ctcgtttata attatttaac aattatgaat tataccaaaa
     5161 catcattgaa aagaaaataa aacctaaaga cacctgggga atgtcatttg gctaaatgta
     5221 tgccgctatg ttaaaatgag agggatttgt aaaaaggaga cgaaaatatg attactttaa
     5281 aatcagcacg tgaaattgaa atgatggcag aatctggagc tttattagca gatgtacata
     5341 aaaatctgcg tgattttata aaaccaggaa tcacaagttg ggatattgag gtatttgtca
     5401 gaaactatat cgagagtcat ggcggaattg ctgcgcaaat tggctttgaa gggtatgaat
     5461 atgcgacttg tatcagtata aatgatgaaa tttgtcatgg attccctcgt aaaaagcctt
     5521 tgaaaaacgg tgatttggta aaagtcgata tgtgtatcga tttgaaaggc ggcatttctg
     5581 attcttgttg ggcctatgta gttggagaat ctacacctga gatcgaccga ttgatggaag
     5641 taacgaagaa agctttgtac atcggtattg agcaagcaca agtagggaat cggattggtg
     5701 acatcggtca tgctatccaa acttatgtag aaggcgaaaa tctagcgatc gttcgtgatt
     5761 ttattggtca tggcgttggt cctacgattc atgaagaacc agcagttcct cattacggag
     5821 aagctggaaa agggttgcgg ttgaaagaag gcatggttat cacgatcgaa cctatggtta
     5881 ataccggaac ttggaaaatg aaaatggatc ctaacggctg gactgcgtat acaagagacg
     5941 gcggactttc ttgccaatat gaacatacat tggctattac taaagatggt ccaagaattt
     6001 tgacatcaca aggagaagaa ggcacttatt gatctatcca gtcaataggt acgggagagg
     6061 tacatgaaag tttggaacaa aataaaacaa aatgaaaatc tgatgcgctt tattgagacg
     6121 actcaaaagc gcatcactga ttcagaaatg agtacgacct ctgtcgtcgt tgcttattat
     6181 ttactcttgt ctttatttcc attgattatt gcttttggta atattttacc gtttctccac
     6241 atcgatcaag agactgtact gacctattta cgagaagtga ttcctgagac cgtttaccag
     6301 tttatcggtc ctgcaatcaa agaccttttg acacaaagtt caggaggctt gttatccgtt
     6361 tctgcattag cggctttatg gtctgcaagt caaagtatca atgctttgca aattgcgatg
     6421 aataaagcgt atggcgtaga aaatagaaaa aattttttga tcgtccgttt cttctcacta
     6481 attgtcattg tcttgttcat gattgctatt agtggggtaa ctatcgttct tgggttggga
     6541 cagctgattt tggatgctat tcagccaatc gtacaaatac ccgtgaactt tatcgatcag
     6601 ttccaaactt tgaagtggcc aatcacattg gtagctttat ttgtcatcat gttcttgatt
     6661 tatttaattg tccctaatgc tcagttgaag ttgaagacga tcattccggg cacgatcttc
     6721 gctactgtcg gctggatgct gttatcacaa gtgtttagta tctatgctag gtattttgca
     6781 acgaggatca gcggttatca gatcatagga agttttattg tactcatgct ttggcttaat
     6841 tttgctgcta cgatcatcat tttgggcgga atcatcaatg cagttgttca agaatacgtg
     6901 acgggtcatc aaatcaaaaa acgtcgagat ccaagccgaa aatggttcaa taaattgaaa
     6961 actaaatttt ctcataaaaa aaagtagaaa caagagttct tattgtaaat ttatatcagt
     7021 aatttataat aattatgact cttaattaaa gtaggtgccc atatgcttgt ttcttttagt
     7081 atggttataa gattttttct gacaatttta ttatcactga tattaacacc tgtattcaaa
     7141 atcatttcag tacaaacagg tatggtcgac aaaccaaatg aaagaagaat aaataaagtt
     7201 ccaatgcctt cagcgggcgg actgcctatc tttatttcat ttgttatatc gactttattc
     7261 ttattccgta aaattatccc tcaatcgtat attgtaccga tcttgattgc ttctttagta
     7321 atcatagtca caggagtgct cgatgataaa tatgagctga cacctaaaca aaaaagtata
     7381 gggatcttga ttgcttctct tattatttat tttgtagcag atatacgtat tgattccttc
     7441 acgcttcctt ttattggata tatccaacta ggctggctta gttttcccgt aacgattttt
     7501 tggatcttcg gtatcacgaa tgcggtcaat ctgattgacg gtttggatgg gctggcggca
     7561 gggatttcat tgatcggttt aattacgata ggaatcattg gatatttttt cctccatgct
     7621 tctacagtgt atattccagt tgttattttc tgtcttgtag caagtattat cggttttttt
     7681 ccttacaatt tttatccggc aaagatttat ttaggcgata caggagctct attcctaggg
     7741 tttatgatgg ccgtcctttc actacaaggg ctgaagaacg tgacttttgt ttcatcgatt
     7801 tctttgctga tcgtcatggg agtgccggta acagacacgt tttttgctat cattaggaga
     7861 aaagcaaacc gtgtttcttt ttctacagca gataaaaaac atcttcatca ccgactaatc
     7921 agtttaggct ttactcataa aggtgctgtc ctgacgattt atgcgatggc tttgatgttt
     7981 tctttcacag ctatggtcat gaattatact ggaagaatcg gaacgatcat attgattatt
     8041 gccatgttgt ttgctgcaat tttattattt gaattgattg gtctgatcaa tgagaaacat
     8101 cagtttattt taaaaacatt gcgattttta gggaataaag agtaccgtac gcaagtaaaa
     8161 cagaaatatt tgaagaaatg gaaccgtcat atagatgaat aacaaattaa accagccgat
     8221 ccttattagt attgtgacgg caaacagtga taaaattttt cggacactag ataattttat
     8281 ttcaactgta aaagatgaaa cagcagtaaa aatccgaatt tttgacaaca attcacttcc
     8341 cgagtacaaa aaaagactaa cagagtatag gaaatatccc tacatcgata tctattttca
     8401 tgatgaaaat tccggatttg gttatggaca taatcacaat ctgatagcta gcgattctcg
     8461 ctatggcatt atttgtaacc cagatatttt agtggatgaa gagacagtta cagcattggt
     8521 cttgttattg aaagaacatc cggaatgtgc gatgttagca cctaagattc ttaatgaaga
     8581 tggaacaact cagcacctca tccgtgagca gctggctgtt tttgattacg ttttgcgctt
     8641 tgtgcctttc aaatgggtca aaaaaaagtt tgacaaacga ctggctgtgt ttgaatgccg
     8701 aggattgcct actgatgcta atagttatgt acggatgatc tcaggtagtt ttatggtagc
     8761 tgatattgat aaatttaaag agataaaggg gtttgatgag cgtttcttca tgtactttga
     8821 agacaacgac ttgtgtttga gttttgaaaa agcaggttac aagttattgt acacaccctt
     8881 ttatgcagtt atccattttt acgggaaggg tgcgcatcga aatgcaaaac tgtttcgcgt
     8941 gtttttgact tctatgatga aatttttcaa taagtggggg tggcgttttt tctgatgaaa
     9001 ccagaaatat tagtagtcgt tgtgctttat cagcaactat tcagtcaatc tccagcttat
     9061 ggaccattaa gcaaagcact tagcgaaaag caaattcagc ttattattta cgataatagt
     9121 cctcaaaggc agcaaaatga gctgtttgaa aaagaaaata tcgtttatca tcatgatccg
     9181 caaaatcctg gtttagcggt ggcttataat tttgcgttgt ctcaagcaga tgaaggaaca
     9241 cgttgtctcg tcactctgga tcaggatacg aggctagtcg acgattattt tgaactattg
     9301 cgtaaagtaa cctttacaga tgaatgtgtt gctgcagttc cgatgatttt ttctgggagc
     9361 cgacaagttt ctcccctata ttcagatcgt tatatcaatc gtacagctca agcagtagaa
     9421 gttgaaggcc caacagctga acgaatcatg gcaatcaatt caggtgttgc ctggtctgtc
     9481 aaatttctaa aaaagattgg cgggtttaat cctgcttttt ctttagattt tttggatcat
     9541 tggctgtttt ggaaagtgga tcagttggaa aaaactgtgg agatccttcc tgtacgaatg
     9601 gaacatgatc tttcggtttt agactatgaa aaagtttcaa gtaatcgata ccgttctatt
     9661 ttacaagcag aaaatcgatt ttatcatgaa tatgatcaaa ggcatttatc cagtcaccga
     9721 cgacaattat tgttaagaac agctaaacag ttcttgaccg tcaaaaaccg gcatatctgg
     9781 cggatgactt tgcgctcata tgttaagaat tggaaggtgt gaattcgtgc gttcggtttg
     9841 tatagctacc tttaatggag gcagatattt aagagagcag ttagatagta ttttatctca
     9901 gctttcagca gaagatgaag tagtcatttc tgatgatggg tcagtagatg atacatggga
     9961 tatattaact gaatacgcag aaaaagataa gcgaatccag cttttttcgg ggcctcgtca
    10021 aggattgatc gctaattttg gttatgcgat ccagcagacg aaaggagatc taatcttttt
    10081 ggcagaccaa gatgatgttt ggttggagac aaaagtgaaa aagatcactg actattttga
    10141 gcagaatccg gatcagctag tagtagtttc tgatttaatc attgtggaca gcgagctgca
    10201 agagatccat gattcgtatt tttcgtttcg aaattccaaa gaaggatggc ttaataatgt
    10261 gataagaagt cactatattg gtgctggtat ggctttccgg tcttctttaa aacccgatat
    10321 tttgccgatc ccgtcagaag tgccgatgca tgatatgtgg attggtttgc tgggaggaaa
    10381 gaagactggg ttcctaagag aaccgttaac tctgtaccga agacatgatt taaacgcgag
    10441 tgagattgaa acacattcta aattacggca aaaaatttct tggcgtgttc atctgattac
    10501 ggcgttgatc aaacgaaaat ggtttaaacg ttgataaaag atgtttaaat ccttaatatt
    10561 tccatgacaa atataacaat tgatgagata ataacaaagt gaaatttgaa atcaaaaagg
    10621 agagcagata tccatgaagg gaatcattct tgctgggggc agcggaacac gtctgtaccc
    10681 tttaacaaag gcaacatcga aacaattgat gccgatttat gacaaaccaa tgatttatta
    10741 tccaatgtct actctgatgt tggcgggaat caaagaaatt ctgattattt caacgccaca
    10801 agatacacca cgtttcaagg aattatttgg aaacggaaat gatttaggac tgcagatcga
    10861 atatgcagta caagaaagtc cagatggatt ggcacaagcg tttatcattg gagaagaatt
    10921 tattggagat gatagtgtct gcttggtatt aggggacaat atttactatg gtggcggtct
    10981 gtctaaaatg ttgcaacgag cagcttcaaa agatacaggc gcgacagtat ttggctatca
    11041 tgtcaatgat ccagaacgct ttggtgtagt agaatttgat gagaatatgc aagctttgtc
    11101 gattgaagaa aagcctgctc agccaaaatc aaattacgct gtaactggcc tttattttta
    11161 tgacaatgag gtaatttcta tcgctaaagg tatcaaacct tcagaacgtg gagaactaga
    11221 gattacggat gtcaataaag catatttgga taaaggaaaa ctatccgtag aacttatggg
    11281 acgcggattt gcttggcttg atacaggaac acatgaatca ttgcttgaag catctacctt
    11341 tatcgaaaca attgaaaaac gtcagaactt aaaagtggct tgtttggaag aaattgctta
    11401 ccgtatgggc tacatcgata aggaacaatt gctggccctt gcacagccat tgaaaaaaaa
    11461 tcaatacggt caatatttat tgaatttggc cgctgaataa ggagtcctta cagatgaaag
    11521 taacagatac aaaattaaca gatgtcaaaa tcgtagaaat ggacgtcttt ggcgatcatc
    11581 gcggtttctt cacagaaagt tattcaaaag caaaatttgc agaacatgga ttgaaatatg
    11641 actttgttca agacaaccat tcactatcag ctgaagctgg tgtccttcgg gggcttcatt
    11701 tccaaaaagg agaagctgca cagacaaaat tgattcgggt agtcactgga gcagttttag
    11761 atgtagtagt ggatatccgc aaaggtagcc cgacttatgg tcaatgggac ggatttatct
    11821 tatctgaaca taatcatcga cagttgcttg tacctaaagg atatgcccat ggattcgtta
    11881 ctttgacacc aaatgtgaac ttcctttata agtgtgataa ttactataat gcagaagcag
    11941 atgggggcat cgcatttgat gatccagatt tagcgattga ttggccaatt gatccatcaa
    12001 gagcgattat gtcggaaaaa gatcaccgtc atccgacatt aaaagaattt gaagcagaaa
    12061 atccatttgt ttacggagaa atctaagaat taaggagaaa ttttcttatg aaaaacatca
    12121 ttgttaccgg aggtgccgga ttcatcggct ctaatttcgt tcattacgtg gtaaacaatc
    12181 atccagaagt gcatgtcact gttttggata aactgactta tgcaggaaac aaagagaact
    12241 tggccggact tcctagcgat cgcgtagaat tggtcgtagg agatgttgca gatgcagaat
    12301 tagtggaccg tctagtaaaa gaagcggacg cagttgttca ttacgcggca gaatcccata
    12361 acgataattc attaaaagat cctttcccat ttgtacaaac gaatatcatt ggtacgtata
    12421 cacttttaga agcttgccgc aagtatgatg tacgctatca tcacgtatct actgacgagg
    12481 tttacggcga tcttccatta cgtgaagacc tgccaggaca tggggaaggc gaaggagaaa
    12541 aattcactgc ggaaacacca tataatcctt caagtccata ttcttctaca aaagctggtt
    12601 cagatctgtt agtaaaagca tgggtgcgtt cttttggctt acgtgcaacc atttcaaact
    12661 gttcaaacaa ctatggtcct tatcagcata ttgaaaaatt tattcctcgc caagtaacga
    12721 gtatcttaag cggtattcgt ccaaaattat atggcgaagg aaagaatgtt cgtgactgga
    12781 tccatacgaa tgatcattct tcagcagtgt ggctgatttt gacgaaaggc agaattggcg
    12841 aaacctatct gatcggtgca gacggtgaag aagataataa gaccgtgatg gaattgatct
    12901 tagaaatgat gggccaacca aaagacgcat acgaccatgt aaacgaccgc gcagggcacg
    12961 atttgcgtta tgcaatcgat tcgacaaaat tgcgagaaga gctaggttgg cagcctgagt
    13021 ttacgaactt ccgtgatggg ttggctgaca cgatcaaatg gtacgaagaa catgaagact
    13081 ggtggaaaaa agaaaaagag gccgttgaag cagcatatgc caaaaatgga caataataca
    13141 gaggaaattt cactgtatta atggaaaaac acatgtgagg caggcgctcg cctgtctctt
    13201 ttttaaaata aaaatcaagg agcggataac catatgtttt tattaactgg aggaaatgga
    13261 caattaggta cagaattgcg ccatttatta gatgaaaaaa atctgccata tgtttcaaca
    13321 gatgcaaaag acttggatat cacagatgct gagaaaacaa tggcttatat tacagaatta
    13381 aaacccgatg ttattttcca ttgcgcagct tacacagcag tagataaagc agaagaagaa
    13441 gcaaaagaat tagatgagaa aatcaatgtc gatggcacaa gaaatgtagc acttgcagca
    13501 aaagctgtga atgcacaatt cgtctatatc agtacagact atgttttcga tggaaaaaac
    13561 aaaaatgtag aatacgaagt agacgaccaa acgaatccac taaatgaata tggtcgtacg
    13621 aaattattag gcgaaaaagc agtagaagag attttagaag actattatat catacgaact
    13681 tcttgggttt tcgggatcta tggacacaat ttcgtcttca cgatgcaacg cctagcggaa
    13741 acccgcgaca aactgactgt agtaaatgac cagtttgggc gaccaacttg gacacgtact
    13801 ttggcagaat ttatggtata tgtcatcgaa gaaaaagcac catttggtat ttatcatttg
    13861 tcgaacgaaa atagctgttc ttggtatgag ttcgcaaaag aaatattgaa agatacagat
    13921 gtagaagttg cacctgttac gtcagaagaa tttccgcaaa aagcaacacg tccgcagtat
    13981 tcagtcatga gcctgaaaaa gacagaagcg ttaggttttg tcataccaac ttggcaagaa
    14041 gcacttgcgc aaatgctgga agctgccaaa aaaatgaata agtaatttcc tttttatcaa
    14101 atagaatttg gagcatgata tggaaaaaca aacaagaagt gcacgacgaa aagaaaagcc
    14161 aaaagcgaat caggcagatt cgaatttggt gcttgacctg tttctaaaac tccgctatct
    14221 tattggcgtt ttagtcatcg tggtcatcgt tacttttaat ttaaacggaa gttcacttgg
    14281 tgtttgggat aaatatgtgt cgcaaagaga cgatgggaaa aaaactgatg tgatttttgg
    14341 acagaatcgg gaagtgcggt cagacgaatg gctggtgcag acaccttttt acctctcaca
    14401 agctgaagag gacttttcgt tggtgaacga ggattattca ttaaacggac aaaacatgat
    14461 cattgcgtat aattctcctg taaaggatat tacggttatc ggaaaaccat tcaactgggg
    14521 attctttttc ctcggaagag atcgaggact ttccttttat tgggcgatga aattagtcgt
    14581 catggtcttg cttggattcg aagtactgat gatattaacg aagaggaaaa aagctctatc
    14641 gctaatcggt gcatttgcgc tgacattttc tccagcagtc cagtggtggt tcatgcaaca
    14701 tgtgggcgat ttgattttct ttactttggg actgatgatt gctttttatc attatttcta
    14761 caatcatgat aaaaaatggc tacgaacgtt gatgatgctt ttggtggtta ttttcggtat
    14821 tgggtttatt ttagtgattt acccagccca tcaagtgatg ctggcgtact tgctgatttt
    14881 ttattttgtt ggcctgctta tttactatag caagaaagtt tcatgggatc tgttggatgt
    14941 agtgttgatt ggaggggcag ttttatttat tggcggagtc atggttcatt tctggctaac
    15001 gtcaaaagac gcattgttag cttctttgaa taccttatat ccaggaaaac gggtaagtac
    15061 tggaggaaag tggacgattg gcgaattttt ttctttcctt acaaattgga aaattccttt
    15121 tgaagatatc aactattcga ataactctga agtggccctg ttctatcact tttttccaac
    15181 tgtattccta gcaagtccat ttgtgttatt tggcaaaaaa gatagcgaac aaaagttact
    15241 gggacgtatt ttgatgattt tttgtctgtt ttctatcttt tggattaccg ttgggttgcc
    15301 aaaatggcta gcagaaatca ctctgctgtc ttatgttcct ccattaagag ccatccttac
    15361 ttttagtttt gcggcttgtt tattatcgat ctggtttatc gcttatattt ggagagaaga
    15421 tgttattcct atttggtata aattcatttt gttggcagta aatgcatggt cttatttcta
    15481 tgcgattacg cattcgaaaa tggataatta tttttcggat tttgaaacca tcgcagttgc
    15541 tgtgttggga acagtgattt tagcttttgc attatttggc tggagacgct tgttttacct
    15601 cgcttttgtc gccttagtta tcgtatctgg ctttttcgtc aatccagtcg tagaaggtac
    15661 aggagcgatt tttgaaaaaa cactggcaaa agaaatccaa aaaatcgatc aacaagatcc
    15721 tggtaaagtt tggttgtctg aagatgaatt atataacttc accccaacat tgggagtgaa
    15781 atccttcaat acagtacgct tttatccaga tatagctgca tggaagaaaa tcgatccgaa
    15841 agaagaatac gagaagtatt ataatcggta tgctcataca agagctttta tcgctaagga
    15901 agatacaaag ttcattttag atcgtccaga tatgttttcg gtcacgttga attttgaaga
    15961 cgcagaaaaa ttagggatcg actatgtgat cagtaaacga ccattaactg attacaacca
    16021 attatatgaa gcgcagttca cgcagctata tggaccggat aaagacggtt atatgatttt
    16081 taaagtagaa tatccggatt atccagatgt accacaaaca caaactcagg aaaatcagct
    16141 agtcgtacag taataggcta gctgagaata atcctgaaat attagtagaa aggagagtga
    16201 agataattca agcaatcgta caaaaatttg tcaacaaaat gagtgtcggt ttcttgcttt
    16261 tgttgctgac gctagtcttt tttgtttgga cagcaggggt aggttttcca gcaactttgt
    16321 ttatatataa caatagttca ttacttatcg cttttagtgt ggctattttg ctcattttaa
    16381 atgtttataa agcaaaaggc gtcgattttc tttatctagg tgttgcgctt gcccttttca
    16441 ttttcttttc ttactttcgg gaattaagaa atgagtcttt atttggagac ttactgtttc
    16501 ctttgattat tttattttgt ttagtaatta aatggatcga gtggacaaaa tgggatcgcg
    16561 gtatttatct gattgtcttt acggtcttcc tcggaatcac gttatatcgt gtatttacag
    16621 agatccaagt accagaagga caaagcatct gggctccagg caattcgctt tctgatattt
    16681 ggatcaatac gaatacaatc ggaagttctt tgatgactct tgctttattg atcagtggat
    16741 ttgccagttc ttttgaacga tggtatgttc gaatcatcgg tgggatagca gtcgttgcag
    16801 cctttttagg tatttgggtc tgccaatcta gaggtgcatt agtcgcgttg attgtttttg
    16861 cgatattgga tcttttacct aaatcgttga tgcgtgtcat tcgtgcgcca tttattgcct
    16921 acacggttac gattctttta gctttgccga tttcttatct ggcggctgtc tctgaaaaag
    16981 tcaatttgtt taccggtcga gaagatattt ggcataaatt ctatcagacg ctaggagaaa
    17041 aatctgaaca agttttacta ggaatgaaaa catttatctt ccagcgagga aaccaatttt
    17101 taggaaacca caatagttat aattctattt tgaatatcta tggattgata ggatttggga
    17161 ttgctgcttt gctgcttatc ctttttattg gtcgcttaac gttgaaagca gatttatcca
    17221 acgggcagat gacttttatc tgggcctttt ttgcggtgat gatgcagtca tttatggagg
    17281 atacattgac ttcataccca tgggttccga ttatttatat cctgttggct atggccgttc
    17341 atcgatatga tgaaccagaa gttacggagg aattctatgt tatggaagag gcatatgacg
    17401 atatgactta tgatgataca tcttatgagg aacaaccaga tagcgctcat tcttccagga
    17461 tccaacgcta tcattgatag gcacaaaata cgagagaggc tgtgacaacc gtcgcagcct
    17521 tttttggttt attgcaattg tctagcatct tctgtaaaat agaaacgtta gagaaaatct
    17581 tgtatcatag aaaattaaga aagaaataag aacgcagctc ggtaccaaaa atatggtaaa
    17641 atggcacttg actgtaattc actgaaaatc gcttggagga acacaaatgt ttaaagattt
    17701 gtatttattt atgaaggaca tttatcagaa cagaaaatta ctgctacagt tttcgatcaa
    17761 tgacttcaaa tcaagatatg caggatcgtt tttaggaatc ttatgggcgt ttatcaatcc
    17821 gctatttact gtattgattt attggctggt atttggtgtt ggactgaaag cacaaatgat
    17881 cgatgcaaaa tacccattta tcgtatattt agttaccggg atgattccct ggttcttctt
    17941 ctcagatgca tttgcatcaa ctacggttgt ttttcgggaa tatacttatt tagtaaagaa
    18001 agtcgtattc aatattcgta tcttgcccac gacgaaaatc ctatccaatc tgtacaccca
    18061 tttattcttc attctgattg gcatagctgt cgcgcttata aatggtatat atccttcagc
    18121 aatgtcttta cagctgattt attatttatt ttgcatgtgt gctttcttga caggattgac
    18181 ttggctgacg gcatcgatcc aaccattttt acctgatatc atgcaattaa ttacgatcgt
    18241 gctgcagttg atcatgtgga cattaccgat attatggagc cctaatcagt ttgattcagg
    18301 tcttgtaagc atattgaaat taaatccgct gtactatgtt gttcaaggtt atcgtgagtc
    18361 atttttaagt gaagcttggt tctgggagca tggaacatat actttgtatt tctgggtttt
    18421 cacgttagta atgttcgtaa tcggctctgc agtgttccgt agattgaaac cacatttttc
    18481 agatgtgctg taaggagaat agctatgaca gaatatgcaa ttagactaaa agatatcaca
    18541 aaatcttata atatgtacgc aaaaccttcg gatcgatttc gtgaagccct caatcctttt
    18601 aagaaatcct atcatgatgt attttatgcg ttgaaaaacg tgaatgtaga aataaaaaaa
    18661 ggtgagatga tcggtttcgt gggagaaaac ggatcgggaa aatctacaat gttgaaaatc
    18721 attacgggag tactgacacc aacatccggc acgatggaaa tcgaaggaaa aatctcagct
    18781 ttgctagaac taggatcagg attcaatcct gagtattctg gctatgaaaa tatctattta
    18841 aatggaatgg ttctaggatt ttcaagagaa gaagtcgatg aaatggtcga tgatatcatt
    18901 gaatttgctg acatcggcga ccatatttat caacctgtaa aaacctattc aagtgggatg
    18961 ttcgttcgtc tagcttttgc tgtagcgatc aatgtgaatc ctgatatttt gattgtggat
    19021 gaagcattgg cagtaggaga tcttgaattt caactaaaat gtatggaaaa atttacagaa
    19081 atcaagaact cgggaaagac gattttattc gtttctcatg atattagttc gattcgccgt
    19141 ttttgtgatc gttcctattg gttgaaaaat ggaaaagttg tcgaatatgg tgatacgatg
    19201 gaagtaacga cgaattacga aaactttttg aagaaaaaat cagttaaaac agtagatcga
    19261 aataaaaacc aagtagaacg cttcgcagct ccagatatcg tagacgtgac gaaagccgaa
    19321 ttgttggata aagataaaaa tccagtggat atgctggaac aaggagaaaa actatacgtt
    19381 aaagtaacct atgaagtaaa agacgataca atcaaaaatc cagttttagg aattgctctg
    19441 cgtacagtcg acaattttta tgtgtgcgga ctcaatactc tactagatgg tatcaagatc
    19501 ccttggaaaa aaggtgagaa tatcttttat ctggagtatg aaaagttagg tttgttagct
    19561 ggtgaatatt attttgacgt tgcggtcttt gaagaaaatg caacggttcc tttggtatac
    19621 aagacaaaat acatgaactt gtttgtcagc ggttcttata tcggagaagg catcgtggtc
    19681 ttagaccata aatgggaaga agggactcat agcaatgaaa tatgattttg aaatggacct
    19741 agatgaacaa agcagtgtgg gaaaaattgc cgcacagatc aaaccaggaa gtaaagtttt
    19801 agagtttggt cctggaaacg gccgattaac gaaacatttg atcggagcaa aacaatgtga
    19861 agtgagcatt gtcgagctag ataaggaatt gttcgatttt gtcagcgagt ttgcccaaga
    19921 tggattttat ggagatatcg aaagttttga atgggcaaac tattatgctg gacaaacatt
    19981 tgattacgtt ttgtttgccg atgttttaga acatttggta gatcctggaa aaacgttgaa
    20041 gaaagttaga gaatttttga atgaagaagg agaaattcta attacattcc ctaaccttgc
    20101 gcataattct gtcatgattg atttgttcaa taatcaattg ccatgggctt cttatggttt
    20161 gctagatgaa acccataatt ctttttatac tcatgatggc ttccaaaaag tttttgaaaa
    20221 agcaggatta tacatcaata ttgaagatta tttgtactta gctgtaggtg atacagaatt
    20281 aaaatcaact tatgaagaat tgccggaagc tgtacgttat gatttcaaaa tgcgaccatt
    20341 tggcgaagtc taccaatact tcttctcatt gatgaaacat ccagtagcac aaagttccat
    20401 tgcgcagccg caaaattcta attatgtgaa agtattagaa gtaatccagc aaacgaaaca
    20461 agatgaaata attcaacaaa taccattcaa taatttcaca ggggaaaatg agacactaag
    20521 tttccatgta tcagaattag cagaacgaat ggtgtttcgc ttcgcgcagc aacctagctt
    20581 tatcgaattc agcgcagaag ctgctggaga aaaactcaca tttatcgatt caaatgctgt
    20641 agtcaaaaca gtaaatgatt gttatttgtt tgatggtaaa gatttaccag agttcttttt
    20701 aacggatatt gcagggaaag aagtgactat ccattgtcac tatcgtttta tcggagaatt
    20761 gacaccaaca atgaaagaat tgctggaaac aatccgtcca atggctgaag ttacaaagca
    20821 gctttctgag aaaaatgatg aattagaaag agaaaatcat tatcttattg agaataatac
    20881 aagattagat cagacgttga aaacaaccat aaatcgctat tgcacgttgt tggaaagtga
    20941 tgaatggaca atcaaacata gattagggcg acgtaagaaa gaaacatcga aaaaaatcca
    21001 agaaaaagag ctttctctat gtattgacga aaaaatctgg gatgcagaaa caaagatatt
    21061 gaaaatcatc gggtggggaa tcgctaattc ggatcgccaa ccattgtcct ataagttatc
    21121 agccgaccaa tcaccatttt ttgaagcaat tcctgtttta cgagaagaag tcaatcaagc
    21181 aaaacagcta gctgaaggag caaaagcagg atttgaactg cggatccttt gcgagaagga
    21241 acgttcattc ttagttgaag cagtggctca aaatggtcaa tcatggatca ttgaaatgta
    21301 aataatgatt aacttataaa gataaggagt aaacgaatcg tgcaaaaaaa agaaattgcc
    21361 gtatttatcg atcaaatcac tcgtgaacgg gccactggcg atttgcttat tgtgggctgg
    21421 gcaattgatg aagtgaccaa agaaatccct acgataaagg tagaaaaaga aaatgtgatt
    21481 gctgaagcaa cacatgtcgt aagattggat atcaatcatt tatataatct tgatgttaag
    21541 acccaaagcg gttttaaggt acgtttatca gggaaaatga gaggaaaagc aatcttagac
    21601 ttccaaacag caagacatca aaatggcata gctgtgaaat taaacggtaa atatccttat
    21661 gatgacggca ttgaatcttc atgggaaaga aaaaaaagat tactgaaaaa agggataaat
    21721 tatgcaagga ctcatggcgt aaaaaaagca atccgccggg tcaaactgga attgaaacca
    21781 ggatcgatcg actatgcaga gtggatcagt cgtcatgaga aacctgatct gaaagagcaa
    21841 aggaaagaag tacaaggatt tgcctaccgc ccattgattt ccatacttat gcctgtctat
    21901 aacgttgaaa tcaaatggct cgaaaaatgc attgattcgg tacttgatca aacgtatgat
    21961 cactgggaac tatgtatcag tgatgatgct tctactgatc cagctatccg aaagtgtcta
    22021 gaatcctatc aagcaaaaga tgatagaatt aaagtcgttt tccgacaaga aaatggacac
    22081 atcagtctgg caactaattc tgcattgaaa atggcagaag gagagtttat agcgctctta
    22141 gataatgatg acgaattacc tccatttgcc ttatatgaag tggcaaaagt gctaaacgta
    22201 catccagaac tggatttgat ctacagtgac gaagataaaa tcgatgcaga tgggaatcgc
    22261 tttgacccgc acttcaaagc agactggtct cccgatacat tgatgggaaa taattatatc
    22321 tctcacttag gcgtatatcg gacaagcatt gttaaggaac ttggcggttt ccgtaaagga
    22381 tatgaaggct ctcaagatta tgatttggtt cttcgtgtga cagaacaaat tcctgcagaa
    22441 cacatttacc acattgaccg tgtcttgtat cattggcgga cgatcccggg atcaactgca
    22501 agcaatggag aagctaaaag ctacatctat gattctggag tgaaagcatt gacagatgct
    22561 ctatctagaa gaaatatcaa gggaagcgta catcctggca gaatttctgg tttttatgaa
    22621 atcacttatg atgttttgca agaagacttg gtcagtgtga tcattccaac taagaatggc
    22681 tatgaagatc taaaaacttg tgtggattcg atcatcgaaa aaacgtctta tccaaattat
    22741 gaaatcatta ttgcagataa tggaagtaca gatcctaaaa tgcaagaatt atttgcagaa
    22801 tacaagcatc agctgaaaga ccgatttatc gtcgaattaa ttgacattcc attcaattat
    22861 tcacgtatca acaatctggc agcagaaaaa gcaaacggca aatacttttt attcttgaat
    22921 aacgatacag aagtgattga acctgactgg atgacagcga tggtttctta tgcacagttt
    22981 gatcgaatcg gctgtgtagg agcaaaatta ttttatccgg atgatacaac gcagcatgca
    23041 ggtgtattat tagggatcgg tggcgttgca ggacatgcat tgaataacta tgatcgaaca
    23101 cattgtggtt actttggccg attggtcatt gacgtcaatt acttagcagt cactgcagct
    23161 tgtatgatgg tcaaggcagc tgacttcaat gctgtcaatg gatttgatga aatattagaa
    23221 gtagcattca acgatgttga cttgtgcttg aaagtttatg aactgggtcg ttacaatgtc
    23281 tatgcacatc aagcagaatt gtaccatttc gaatctaaat caagaggtta tgaagataca
    23341 ccagaaaaac aaagacgttt tgctggggaa atcaaaaaaa tgcaagataa gtggccttct
    23401 tatattgctc atgacccatt ttataacgat aatctaacta aagaaggaat cggcgatttt
    23461 tcgttgagac ctgattgatt aaaagaactg tattttcatt tttattaatg aaaatacagt
    23521 tct
//
LOCUS       DAFKHN010000044        23126 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFKHN010000044 DAFKHN010000000
VERSION     DAFKHN010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.044"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..660
                     /locus_tag="LY912_001693"
     CDS             <1..660
                     /locus_tag="LY912_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6955378.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
     gene            820..1107
                     /locus_tag="LY912_001694"
                     /pseudo
     CDS             820..1107
                     /locus_tag="LY912_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
     gene            complement(1209..1925)
                     /locus_tag="LY912_001695"
     CDS             complement(1209..1925)
                     /locus_tag="LY912_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBM6955379.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     LKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(1894..3543)
                     /locus_tag="LY912_001696"
     CDS             complement(1894..3543)
                     /locus_tag="LY912_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBM6955380.1"
                     /translation="MFPFFKKKPLKLQNTIILVVCFSTFVSLIVSAILIRNFILSMNR
                     SSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIMIASNLDFIVVMDPEGIR
                     YSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFRYFVPIYYNQEIIGAVCV
                     GLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMKKVLLGLEPQEIAEQLSE
                     KTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDFEVGKKISDNLYDVLFKE
                     TIEHQTTVRTQSMYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGTKQ
                     YINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVPAI
                     AGFLLGKINEAKEQSVEMLLETDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQKHE
                     RNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLIHS
                     IVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            3718..4242
                     /locus_tag="LY912_001697"
     CDS             3718..4242
                     /locus_tag="LY912_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBM6955381.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            4258..5757
                     /locus_tag="LY912_001698"
     CDS             4258..5757
                     /locus_tag="LY912_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBM6955382.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMNEE"
     gene            complement(5845..6448)
                     /locus_tag="LY912_001699"
                     /pseudo
     CDS             complement(5845..6448)
                     /locus_tag="LY912_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
     gene            6553..7509
                     /locus_tag="LY912_001700"
     CDS             6553..7509
                     /locus_tag="LY912_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBM6955383.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCERLLTFIRESQEDAREHQENYWLRQPLYYETCFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILARIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(7814..8770)
                     /locus_tag="LY912_001701"
     CDS             complement(7814..8770)
                     /locus_tag="LY912_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBM6955384.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMIHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            8944..9504
                     /locus_tag="LY912_001702"
     CDS             8944..9504
                     /locus_tag="LY912_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955385.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            9497..10321
                     /locus_tag="LY912_001703"
     CDS             9497..10321
                     /locus_tag="LY912_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBM6955386.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            10331..10948
                     /locus_tag="LY912_001704"
     CDS             10331..10948
                     /locus_tag="LY912_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBM6955387.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            10966..11649
                     /locus_tag="LY912_001705"
     CDS             10966..11649
                     /locus_tag="LY912_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBM6955388.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            12332..13615
                     /locus_tag="LY912_001706"
     CDS             12332..13615
                     /locus_tag="LY912_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBM6955389.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            13631..14518
                     /locus_tag="LY912_001707"
     CDS             13631..14518
                     /locus_tag="LY912_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6955390.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            14535..15371
                     /locus_tag="LY912_001708"
     CDS             14535..15371
                     /locus_tag="LY912_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6955391.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            15374..15997
                     /locus_tag="LY912_001709"
     CDS             15374..15997
                     /locus_tag="LY912_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955392.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            15994..17286
                     /locus_tag="LY912_001710"
     CDS             15994..17286
                     /locus_tag="LY912_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBM6955393.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      17645..17742
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            17858..18439
                     /locus_tag="LY912_001711"
     CDS             17858..18439
                     /locus_tag="LY912_001711"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBM6955394.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            18442..19749
                     /locus_tag="LY912_001712"
     CDS             18442..19749
                     /locus_tag="LY912_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBM6955395.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            20165..20653
                     /gene="purE"
                     /locus_tag="LY912_001713"
     CDS             20165..20653
                     /gene="purE"
                     /locus_tag="LY912_001713"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBM6955396.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            20646..21770
                     /gene="purK"
                     /locus_tag="LY912_001714"
     CDS             20646..21770
                     /gene="purK"
                     /locus_tag="LY912_001714"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBM6955397.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            21783..23078
                     /gene="purB"
                     /locus_tag="LY912_001715"
     CDS             21783..23078
                     /gene="purB"
                     /locus_tag="LY912_001715"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBM6955398.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
BASE COUNT         7316 a         4048 c         4963 g         6799 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttcta ccggtcaaaa atttgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaattgtg gacataaaga cggcaagaaa
      541 tctctcgaaa ttcgagaatg gacttgccct atttgtcata ctcatcatga ccgagatatc
      601 aacgctagta tcaatatcct gaccgaaggt ctaaggctac actctatggg attggcttag
      661 atcaaataaa caagaaccgt aggaactacg gggatagctt ggtaaataag aggcacctct
      721 gttagtaaag taatacgcta tcaagtatgc tctcttccca agaagctccc acttcaagcg
      781 taagaaaccg ttaggtttag ctaagtggtg agtagttcac gagctttgaa aagcaatcat
      841 ttagctggtt ttgcaaccga tgtttttgca aatgaaacag aggttttttt ccgatccttc
      901 aagccatggg agacgattcc agaccctgct atccagcaat tagtagaaat gtaccctaga
      961 gttcttgtaa ccccgcatgt aggttcaaat acagatgagg cattatcaaa tatgatttcg
     1021 acaagtttcg agaactttcg tgaaataata gaaactggaa aaacgaaaaa tgaggtatct
     1081 cttcctaaag cccgtcaatt aagataagaa aacatggata ttcgtcaata aaatgtttaa
     1141 aaatagtcca agtaaacagt tgttacttct gtatacttgg actattttgt atgggataat
     1201 tcgatgactc aacagtaatc tgtgagcttt ttccgcccat tctttgtcaa ttcataacag
     1261 gttagcggcc ggccgatttc caaatatttg attctttcgt tcaatatatc ttgttctacc
     1321 aaaaaattca aatatttctt gactgatata cgtgacagtg agcttttttg agccagttct
     1381 tttgttgaaa aaatagtatc ttcttttaga ataaatgcac ttattttttt taaagtcagt
     1441 tttaacagac ctttaggcaa atcgatgaat gatggtattt cgtgaatggg agtggtgtgg
     1501 ttgaatactt gatcgatcaa tttctgatcg gctttttcag tcgtttggat tgtctgagag
     1561 aaagcaagat acttttcgat cgccagctga aaacgttgca aagtgaacgg tttgatcaaa
     1621 taatctaagg caccgtagcg gatcacattc tttatggttt cgatatcatc tgcagcagtg
     1681 atcaaaatca ctgggatatc atttccttgc tgtctaagcc aagataaaaa atggatacca
     1741 ctttcgccag gcatgtatac atcaagcagc agcagatctg cgtttttttg tctgaaatat
     1801 ttttttcctt cttctacatt tctgaaactt tcgattacgt tcatattagg gatgctttcc
     1861 acaaaagtac gattcaattc tgcaaccatt ggatcatctt cgattatcag gacatttgtc
     1921 atcattttga tcttcctttt ttggtaattc tagatagacg attgtaccgc catttgtttg
     1981 tttggaaaat tctaaaaatc caccgtggcg tttgacgatt gaatggatga gattcaaccc
     2041 aaacccacga ttaattccct tcgtcgaaaa acctagcgta aatatttttt ctgagatttc
     2101 ttctgatatc ccgacaccgt catcgcagac ggtcacgatg aatacttcag cttctgtgtc
     2161 atagtttaaa tgaatccgga cctgtccgtt tctttcatgt ttttgtagca cggcttcttt
     2221 tgcattatca agtaagttcc ctaacacttg caaaagtgaa tggatggagt catccatctc
     2281 cattttaggg ataaaagaat cggtttctaa cagcatttca acagattgtt ctttggcttc
     2341 gtttattttg cctaataaaa aaccggcaat tgcaggaact ttgatcagac ttgagacttg
     2401 gccaatctct tttttataat tttgatttag ctgctggata aaatgggtga cttcttcata
     2461 cttcttcaaa tcaatcaaac cagaaatgac atgaagttta ttcatgaatt catgggtttg
     2521 agctctcatg gagtttatat attgtttcgt ccccccaagc tcctccatta atttcattac
     2581 ttctgatcga tttcgtaaag ttgcgactgc tcctaaaaaa cggtcattgc taaaaagagg
     2641 tgtaacgcta gaaatagttt ctatcccatt taaatacatg gattgagtcc gaacggtcgt
     2701 ttgatgctca atcgtctctt taaacaaaac gtcatataga ttatcactga ttttttttcc
     2761 tacttcgaaa tccaatagct gctctgtttg gtagaaaatg ttttttgcag gtgtattgat
     2821 caagaggata gttttatcag aagagatggc taagattcct tcatctactt cattttcgat
     2881 aatcgttttt tcacttaact gttctgctat ttcttgtggt tcaagtccaa gcagtacttt
     2941 tttcattttt tgggcaagaa aaacggcgcc tatgatgcct acgctaagtc cgataatcaa
     3001 tgaaaaaaca atcatttttt gtccatcttt gacttgattg tcaatcgtgt tgttcgttaa
     3061 gccaacacaa actgcaccaa taatctcttg attgtaataa ataggaacga aatagcggaa
     3121 gccgaaccct aacattcctt ctttttcaga gaaaaattct tgtcctccaa tcactttttt
     3181 cacatcttca tgacttgaga aaggaagacc gatgtaactt gggtctgcgt gagaatatcg
     3241 aatgccttca gggtccatga ccacgataaa atctaaattc gatgcaatca tgatttcatt
     3301 tgttattcct tgaatcgcat gtgttgggtc accagtctgc agcttttttt ggatgagttt
     3361 atcattggca acgattttag caatgctaga gattttatct gacacactag atcggttcat
     3421 cgaaagaata aaattcctga tcaatatggc agaaacaatc aaagaaacga atgtggagaa
     3481 acaaacgaca aggatgatcg tgttctggag ctttaatggt tttttcttaa aaaaaggaaa
     3541 cataggctac ctcgaaagaa tttattgtga aaattttaac atgaaaacaa aaatttaaca
     3601 aattgtcaac gataaacaca accttcctat aaaaaacacc actgagtcgg taaaagaagc
     3661 tatacagaat tttcaaacat tggtatgata gacgtagaaa tggaaggagg cgtgtatatg
     3721 atagggggaa tcgcacttga gacgatttat tggtatacat tgctgatttg tgcaggattg
     3781 gcagtcctat tgattatttt tggagatgta ttcgattttg atggcccgct tgatccgatg
     3841 cttattatcc cttggttaac tttcacaagc ttgtttggtt ttctaggtga gcgtttaaca
     3901 gatcaatcat ctttattttt atttattgct agtggaggca tatcgatagt gttggtattt
     3961 ttgcttaatt tctatatatt gatgccgatg aaacatgccg aatcaacgat gtcgtcttct
     4021 gaaaaaactc tggaaggaca agtagctgtt gtgatcacac cgatccctgt acgaggtatg
     4081 ggagaaattc agttgaaaag tgttaccggt tccattagtc gtccagcttg tttttacagc
     4141 ccccaagaac agacagctga gcggggaacg aaagtattga tcattgagat caaggaaaga
     4201 atctgttatg tcatgcctta tgaaagcatg ataaaagctt aaaggagcgt gtgttaaatg
     4261 gaaataccag ttgtttttat cgcgatcgca atcgcagctt tgattttact gatgttgctg
     4321 atcgtctttg tagcgaagta ccagacagca aaaccggatg aagcgttgat catcagtgga
     4381 agttatttag gaagcaaaaa tgtgcacatt gatgaaagca ataacaaaat caaaattgtg
     4441 cgtggaggtg gcgcattcgt cttgccagtt tttcaacgtt cgaatcggat cagtctatta
     4501 tcgagtaaat tggacgtctc cacccctgaa gtgtatacgg aacaaggcgt accggtgatg
     4561 tgtgatggta cttcgatcat caaaatcggt tcatctgtag aagagattgc tacagcagca
     4621 gaacagtttt taggcaagac aagagaagaa ctggaaaatg aagcaagaga agtattagaa
     4681 ggacacttgc gctcgattct tggttctatg actgtagaag aaatctatca aaatcgcgat
     4741 aagttcagtc aaagcgtaca agaagtcgct tctgtagacc ttgcaaaaat ggggttgatc
     4801 atcgtttctt tcactatcaa agaggtcaga gacaaaaacg gttatcttga ctctttaggg
     4861 aaaccaagaa tcgcccaagt caaaagagat gcagatatag cagaagcgga agctctaaaa
     4921 gaaacgcgta tcaaaaaagc tcaagcagaa aaagaatcac aagcagctga attacagcga
     4981 caaacagaga tcgcagaatc attaaaagaa aaagaactga aattagcaac ctacaaacaa
     5041 gaacaagatg ttgctaaagc aaaagcagac caagcctaca atttagaaag tgcccgagca
     5101 caacaacaag taatcgaaca ggaaatgcag attaaaatcg tagaacgtca aaaacaaatc
     5161 gaactggaag aaaaagaaat cacacgtcgt gaaaagcaat atgattcgga agtgaagaaa
     5221 aaagcagatg ccgatcggta cgctaaagaa caagaagcac aagctcaaaa agtcaaagaa
     5281 gtgactgaag ccgaagcaga acgattccgt gtggaagcac tggcagaagc ggaagccaat
     5341 aagacacgtt tagctggaca agcagaagcc gaagcagcac tagcaaaagg aaaagccgaa
     5401 gccgaagcaa aacaaaagat cgccaatgcc ttcaaggaat atggcgaagc agctgtcttg
     5461 agtatggtta tcgatatgct accgcaattg atgcgcgaag cagcacagcc gctaggaaat
     5521 atcgaaaaaa tctctgttgt cgatacagga agcagttcag gagaaaccag tggagcgaac
     5581 cgagtgacaa attatgccac aaatttgctt tcttctactc aagaaacact aaaagcgaca
     5641 acaggacttg acttgaagga aatcgtagag aatttgtcga cacgtgggac tactagccaa
     5701 gtaaatatgt atgaagcgcc aaaagaggca gaacaaaact cgatgaatga agaataaaat
     5761 agtacacttc accgttcaat caaaaatgga ggaagacttt ttaaagttct tctctccatt
     5821 tttttatttt attgcaaaag aaaattagtc ctcgctattt ttcttttgtt tttggatctt
     5881 agcttctatc tcttgtaaat ttgttcttag caatcgttct ttcttttgga gttcgaccaa
     5941 atcttctgat agttcttcct tcttttctgt ttcaggagga cgaagaaaga aattgatacc
     6001 gattgcaatg aatgtcccta taaaagtatc tagtacacgt tggatagcat acaaagcgga
     6061 ttcgccttga gggatgctca acgcaatcag caacaacgta gcgattgcgg aaatgatacc
     6121 ggaattattg ttaataccat ctgacacgac gatcacaata ataactagaa taggaagcaa
     6181 gatcaattct accaaaaaat cattgtgaaa atagcttttg acaaaaaaat aaatgatagc
     6241 taatgtacca cctaatgtat tgccgatgat cctagacttt ccaaaagaaa cggttgtagt
     6301 caagtcctga cgcaaagaaa aaacagcaga taatgcagca atcatcggga ttcctcgttg
     6361 agtcaaatga aaaaacaaga tacataaaaa aaacagctat ggcacttttg atcgtacgca
     6421 tacctagtcg aaaacggcca aattgcatag agattctcct ttttggtctt tttactatca
     6481 tacctaaact tttgtctgat agctagtttt tcattattca agtataatta aaataaaaaa
     6541 agggggaagt aaatgcgtat aggaatgcga acagtcaaaa cagtgatcag tgtcttcttt
     6601 tcgatggtca cagcgggtag cttatcgctg ttgtattggc cagctgcagg gatcattgca
     6661 ttattaagtg taggaaatac caagcgctct acattgcgta cgggcatgaa tcgaatcgca
     6721 gcctttatat tagctacggc aacagcactg ttcagttttt ttgctgttgg gtatactatt
     6781 tttggcttca gtcttttttt attcctgttc atcccgcttg cctctcgctt caaattaacc
     6841 gaagggatcg tagtaaattc ggttttggtc actcattatt tagtggagga aaacatgtct
     6901 tggcagctga tcggcaatga agcgggatta atggcgattg gattagtatt tgctttgctt
     6961 gcaaatgttt acatgccaga tcgtacgaag cagctgaagg aaaaccaaat acagatcgaa
     7021 aaagaatttc gaaatatttt gagacaaatg gcagaatttc ttttatcaga aaataaagaa
     7081 gatgtgcaga tcaaatgcga acgtttactg acattcattc gcgaaagcca agaagatgcc
     7141 agagaacatc aagaaaacta ctggctcaga cagccgctat actacgaaac ttgcttctct
     7201 atgagaagag cacaggccaa tgtgattaaa gacatgctgg aaaatctaga gagaatccag
     7261 caaccagctt attatggaaa acatatctat ggtttattga tttatactgc agaaacattt
     7321 tcagagtcaa atgatggcag acaaatttta gcacgtattg aagaagttta tgtattgtat
     7381 cggcaaatgc ctctgccgac tagtcgccct gaattcgagg atcgagcaga attgttccag
     7441 tttttgcagt cttttaaaag ttttattgaa atcaaggcag aattctccca acaaaaaatc
     7501 caaaaataga ggttgtgaat tcagctaata ttcaggtcaa aaagctgagt tcacaacctc
     7561 ttctttaaac ggtgttctcc tgtcaactcc tcggtcacaa gtcacaatat tcaacaaaca
     7621 tgagaagctg ttttttgaaa ttgctccttg tgactcggag ctgaacggca ggctcacgac
     7681 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagtccag ccaaacgaaa
     7741 aataggagga gctatttttg tttgactgtt cttattactt gatgcagaac agctttttca
     7801 caacctttta aaattacata tttttccata gaacttgcat ttgatccaag atttcgatga
     7861 catcttttgt caagaagaga gagcgattgg gcaagtcacc ttcaatcatg tgtatcatat
     7921 tctttatttc gtaattcatt gcttcagatg tattcccgct ttcgatgaat tcctttgtac
     7981 catctgtaaa taagatctcc gcacgatcag cacgcgggta atcagcaatc gtcacataac
     8041 cgttctcaaa ggcaacgata ccgacttttg gcatttttgc ctgaaaagtc aagctgacag
     8101 cagcaagttc attttctttg ttacgcaaga tagtgactga ttgttcgtcc acgcctgttt
     8161 caaaaggaac cattgtagag gcaactactt caggttgaga gctcaaaaag aaacgagcga
     8221 aagatacagc atacgtaccg atatccaaca gtgctcctcc agctaattct ggattgaaga
     8281 accggttttt agggtctggt tctttgtaac tgccgaaagg tgcttggatc atttttaaag
     8341 cccccagttt tcctgtatcc attattgagc gtaactgctg ataaagtggc atgttgaaga
     8401 ttgtcatcgc ttctgctaag atcaaattct tttcttctgc taagcgcata gcgtcagcca
     8461 gttctttttt attcatcgtg atggcttttt cacatagaac gtgtttgcct gcttccaatg
     8521 ctgccaagat atggtcgata tgctgtctat ttggtacagc aatgtacacg atgtcgattt
     8581 cagcatcgtc taacatttct tgatagcttc cgtaagcttt tggaatattg taacggtgag
     8641 cgaagttttc cgctttttct gaagttctgg aagcaactgc tgttagttcg ctcgtctctt
     8701 gattgaagct ttcggcaaac tcatgtgcga tggtaccaag accaacgatt ccccattgat
     8761 attttttcat ctgaaaacgc tccttcatag ttggattgag tttcttgtct gtctattatt
     8821 ataacaaaaa tcacgaagaa taaagaggag aggacttgaa acattaaaaa aaatgaaagc
     8881 agcgatttaa gaggtgcttt ttgatcaaaa cttaagtaga atagttaaaa ggaggggata
     8941 aacgtgcatc aagtatatat tgatcttatt atgagtgtat tattagaaca gtttgaaact
     9001 gaaaaaaatt ttttagatga atacttgctg atcagtccag aacaatggca aaaatggaaa
     9061 gatggcgaga aaaatctgcc atctgaagcg atgcagaaag taaaaaatct tttcactgat
     9121 tatgaatgga tgctaacgca aaagattttg cgtcaaacga ttatttttcc cgaaaaacga
     9181 aacgttgccg ttgcagagta caagcaaatc aaaacacgca tcgcgcaaaa atggcttagc
     9241 agcaaagcag caaaagtcga gctgatccct ttgaaaaata atcagcaggc tggtagatac
     9301 cttgacttga aagtaagtat tcaatatgat gaatggggct atgatgatat tttgaatttt
     9361 cgtctgccag cagatgttca aaaacagatc gaaggagaaa aaatcgaact tctcgattgg
     9421 gtgaatgaaa atctggaaga aacttacgtt catgaggcga atggggaacg tgaagaacaa
     9481 cgaaaggatt tttcaagtga ataaattttt aggatttgga gcagttgtga ttatgatcgc
     9541 agcaatgggc tatgttattt ttagcgatga tgattcgcat gttcaagccg gcaatcaagc
     9601 agtcgaacga acaagcacca aaacaactgc tagtaaagaa aagaacagtc aaacaaccag
     9661 cagcaaggta aaggacaaag aaacaaaaga tcgtacgtcc aaacaattgc cagatgttaa
     9721 aacagacgat tggaagctag ttttggttgg tccagatcac aaattagaaa aagaaattga
     9781 tgagtctact caattggcat cattaagtaa cggatacttg atcgacaaac gcattgctcc
     9841 agaatatgaa gcatttgcca aggctgctga agcagctgga tttccattag tgatggtctc
     9901 agcttaccgg tctgtatcat cccaacaaca agttttcgaa caaaatgtcc aagatgtgat
     9961 gagtcgtcaa ggtgtatcag aagaggaggc gacaaagatt actaaagaaa cgattacgga
    10021 gccaggatac agcgaacacc acacaggtct ggcagtcgat gtcgtcgatc aaaactggta
    10081 caacagttat ccttctactg tattggatgc aagttacgga gatcagcctg gagctaaatg
    10141 gatcgcagat aatgctgcgc agtatggatt tatcgttcgt tatccaaaag gacacgaaga
    10201 tataactaag atcacatatg aaccttggca cttacgttat gtcggtaaag aaaacgctga
    10261 gtatatcacc aaacaccaat tgacgctaga agaatatctg aatgaattaa atgaaaagta
    10321 ggaattgatc atggcgaaaa aaaagtggaa aaagcaaaag cgcaagaata tccgttggcc
    10381 agcagtggtt gccggtgtag cagtgatact cttagccttt gttttttcct tgaagaatct
    10441 gtcttctcct tttactgata atcagcaaga aaatgaagcg caatcccatc agcaatttat
    10501 tgaacggctt gttccgcatg cccaagaact acaagatggt tatggagtgc ttcctagtat
    10561 cattttagga caagctatat tagaatcaaa ttggggaaaa agtaccttgg ctagcaaata
    10621 caataatctt ttcgggatca aggcttatgg ggatcagaag aaagtaagcc tggaaacaaa
    10681 ggaatttgtt aacgaagaat ggataactat ccaaggagac ttcaaagtgt atgattcatg
    10741 ggaacagtcc atggatgacc atacacaact gttcgtccaa ggagtagatt ggaatcctgc
    10801 gctgtatgaa aaagtgatta cggccaccaa ctatcaggaa gccgcacaag cattgcaaga
    10861 tgcaggttat gcgacagacc ccggttatgc gcaaaaaatc atccaggtca tcgagacgta
    10921 tcaattgaat cagtatgacc ggagatagca aaggagaagt ggctgatggc agaacaattt
    10981 acgccagaaa tcatgacgga attgagaaaa gatatcgtaa gagtaccgga aatcatttta
    11041 gaagcaagcg ggatcaagat atttggaaaa ttgatccgtt cgatcatctt tactacggat
    11101 attgcgatca tacgtaatac aaatgcgaat gcagtaattg ctgtgtatcc ttttacacct
    11161 catccagcga ttactaaaag cattattgag gcagctgaca ttccagtttt ctccggtgta
    11221 ggtggtggtt tgacacaagg tgctcgttct tcctacatga gcatgttcgc agaagcgcaa
    11281 ggttcgttag gggtcgtttt gaacggtcct acgcctttag agacagtaaa agaagtttgt
    11341 cgagtagttg atattccagt tatcagtacg gtaacgtcga aatatacaga aatagatgaa
    11401 aagttagcag ctggtatttc gattatcaat atcagtgcag gtaaagaaac tgcagaagca
    11461 gtacgccatt ttcgtaaaaa atatcctgaa cttcctatca ttgcgacagg tggtccaacg
    11521 gaagaaagta ttgctgagac cattcaagca ggagcaaatg ccatcacata tacgccacca
    11581 agtagcggag agctttttag tcgtaaaatg gaaaaatatc gggaaactga gaaaaagaat
    11641 catgaataac aggtgagaat caaaagacga ggaagagcag atagtggctc ttcctcgtct
    11701 tttgtactcc agtactattt gttcagaatt caaaaaaaag agaaattttt ttgttttttt
    11761 acctgtaatg tacataagaa gagttaaaac cttttgttat tattagcatt ctaacaaaaa
    11821 aatgtcttga tttattgaag cgctttctat agaatgaaaa acgaataaaa actaaaaaag
    11881 gcacccgaca atttagtagc agctaaattg tcggggcttg aaaagtcagc gggaactgac
    11941 caatcaagtt gccatagtca atgcttgtgc atcgacgtgt atattgtacc taatttcata
    12001 cagaattact agttattttt ctgtttttta gggaagagcg cacacgaaga agcatgctta
    12061 tttagctatg tcaaggatat tgggcagttg tctgatatcc ttttttcttt gcgtaattat
    12121 cctcccatca ttgaagcaag aagtgttttt agcgatgaaa gaagaatcag cactatctaa
    12181 tttttcttga aagtattgag ttgttcatcc taggcagaac gataaggcaa gtcttggttt
    12241 ttattcccct tgaaaaagat cgtttaataa atatgttctg tataaaaata cagtatattg
    12301 aaaaataaca atggaagtag aggtgcagag aatgaagaaa agaatgagaa tcatcttagc
    12361 tttaagtgtt atgttattct tcttgacggc ttgtgggcaa gaagatgaca aaaaaatcac
    12421 gctgaacatg gcttggtggg gttcgcaagt ccgacacgat gcaacagtaa aagtaatcga
    12481 gctttatgaa gaaaaaaatc cccatgtgac gatcgattat gaattttatg attatgaagg
    12541 atattacaca aaattaggta cactagcagc atcagatgat atctgggaca ttttccaact
    12601 gaacaatcaa tttcctcaat acatcaatca gattgaacca ttagatgaat atgtggagca
    12661 agggataatt gatatttcta atgcagatga atcctattta gcaacgacga cttacgacgg
    12721 gcaattagtt ggactgtcta acggggtgaa ttcgtttgcg attgcttaca ataaaaatat
    12781 atttgaacaa ttaaatatcc ctgaaccagc ttcaaattgg acatgggatg aatttgaaca
    12841 aatcagctat caaatcactg aagaattagg aatctatgct atttcaagat tcgaagattt
    12901 tatagctggc tgtattattc aaataccaca agttgagaaa ggattgaatt tttataatcg
    12961 ggaagatcta tctaacagct tgggatttga aaatccagac tatctaacag attttttcca
    13021 gctgcgtaaa aatctggtag acaaaggggc ccatccagaa ccaggtggtg gagctgcaag
    13081 tacgacggat ctgtcttttc aggcggttag ggatagagaa gcggcaatgg tgtttctatc
    13141 aagtaaccag ttgacagaaa tattgtcagg ggctcctgaa gatatggaga ttcagttgat
    13201 taatccacct cgcagaaaag cagatggaga atctggtatc cctttacgtt cttcgcaaat
    13261 gctgagtatg gcaaaaagct cagcccataa agaagaagct gctaagttta ttgatttctt
    13321 tcaaaacagt gaagaagcca atgaaatttt aaaaggagaa cgtggtgtac caatcatgtc
    13381 gaatattcga gaacagctcg ctcgtgcaga tgatgcaact ttgcaagcga catttgatta
    13441 tttagaaatg atttccgata tggacaacgg cgaagtgaat gtctttgata gtgctttgaa
    13501 tccggaaatt caagaccaat acaatctttt agttgaaaaa gtcatttatg aagaagtaac
    13561 agcagaagaa gcagcagaga gtctttatga gtttgcgtca aacattctag gatagcagca
    13621 ggaggaaggc atgaaaaaag aaaaactaaa acggttcttg gatcaagaca atgtggtcgg
    13681 ttacgtattt gcttctccat tcatcctagg atttctattg ataacagtga taccgatgat
    13741 cttgtcactt tattattcgt tcaccgatta tcgtttggga aatccagtct catggatcgg
    13801 cttggataat tatataaaga tgctgagtga tgcccgtttt ttgaactcca tccgagtcac
    13861 ttttctctat gtatttgcat ctgtacctgt gaaactgatc tttggtctat tgattgctta
    13921 tcttttaacg aggaatatca aaggaacgac tttctttcgt tctttgtatt atgtgcctag
    13981 tttgatcggt ggcagtattt ctatcgctct agtttggcgg gagttgtttt ctaaaaacgg
    14041 gttagtgaat attttcctgg aacgattagg cgcacctgcg ctttcctggt ttagcgatca
    14101 aaaactggtc atgatccctc ttgttttgat gtctgcttgg caattcggtt cggcaatgat
    14161 catctttgct gcaggtatca aagagatccc aggctcgtat tatgaagcgg cagagatcga
    14221 tggagcgaac aaatggcaga cgttttacaa gatcacgtta cctcttcttt cgccgatcat
    14281 tttgtataac ttggttatgc agacaatcgc ggcgtttatg acttttacgc aggcatttat
    14341 cattacccaa ggtggtccga atgatgccac gaacttttat gctctttatg tgtataacca
    14401 agctttttct tttaattcta tggggtatgc tagtgctatt tcgtggatca tgctgttgat
    14461 tatgggagct gtcacctttc tgattttcaa atcatcaaaa aaatgggtcg ttgtgtgaat
    14521 gagaggagga agaaatgaat aatacagtaa cgaaatggtt tcaatacggt tttattttgc
    14581 tattaggtct agtcatgatt tatccggtct tatggatgat cgcaggttct tttaaaacgg
    14641 atcaagagat tatgagtggt tcgctgaatt tgattccaga gacttttcaa tgggaaaatt
    14701 acgcaaaagg atgggcgggg tttgctggaa tttcattttt tactttcttt aggaattcgt
    14761 ttgtcatctc tgcagtttcg acgataggga cagttctgag ctcgacttgt attgcttacg
    14821 cattatcgag aatcgatttc aaaggaaaaa gattctggtt cgtcgtcatg ttagtaacga
    14881 tgatgattcc tgcacaagtg attttgattc cgcagtttat tatttacaat cggctgaatt
    14941 tggttgggac gtatgtgccg ctgattttac cacatttttt tggacaagca tttttcattt
    15001 accagatcat gcaattcatg gtcagcatcc ccaaagagtt agatgaatca gcgattattg
    15061 acggatgcag caagtatagt gtctttacca aaattatttt tcctttgctg aaaccttcga
    15121 tcatcacgac gatcatcatc cagttttatt ggaaatggga cgacttcatg ggaccattga
    15181 tttatttaaa caagccgaga tcttacacgg tatcgattgc catcaaatta tttgcagacg
    15241 ctggatctag tacgacttac gcgagtatgt ttgcgatgtc tacgttgtcg ctgctaccgg
    15301 tttttctgat tttcttattc ttcaataaat atcttgtcca ggggatcagt acaagcggtc
    15361 tgaagggctg aatatgaaaa agccaataga agagatgttt ctttacaagc tcaactacta
    15421 tgtctgtcgg atttttttaa ccagtcttat cagtaatgct cttttcgctt tagttctagg
    15481 atgtttgttc actttaggat tagtgctgtc tgctcgtgtt gtctatctga tttatttttt
    15541 gatgatgtat ccttcttatt atctatctgt ccattacttg gcagaaaaaa aggtatgttg
    15601 gaggaaagga aaaatcaaac ggatgtgttt catcattacg ttgtttcagc tgtttgtcat
    15661 tatttttgca gttgattggt atttattagt gggaaagatt ggagcttggt atctgattcc
    15721 ttttctattg tgtctgttgc tttttgtatc ccatagtttt tttagtacgc taattgatat
    15781 ctgcaaagaa gataaagcag atagtcttgt ttatttgatc aaaaggaata tctggctgtt
    15841 gtcaaaaaac gtcaaggggt ttctgtggta tttatgcctt ttgtatggac tgttctggtg
    15901 tatacagcat gattttttac tcactgcatt actgtatcca gggctgccat ttgtcacagt
    15961 attttgctta aaagaaaagg agaatgactt taaatgaaga aaaaatatgt acaagtcgga
    16021 cttggtggga gagcgcgttt tttttatgag gcaattgcct ctacgtatca tcaaacttgt
    16081 gaactagtcg gtttttgtga tgtatctcaa acaaggatgg attatgcaaa tcggatactt
    16141 gtgaacaagt atggacagaa aaaagtaaag acatgtatgc catcacaatt tgagcaacta
    16201 ctggatgacg tacggccggc tgaagtcatt attacgtcag tagatcgaac gcatcatgat
    16261 tatatcattc gtgcaatgaa aaaaggatat gatgttattt gcgaaaaacc tctgactatc
    16321 gatgaggaaa aagctcaaga aataataacg gtccaaaaac agacgggaag aagcctgcga
    16381 gtcactttta attatcgtta tgcaccgtat cacacgaaga taaaggaact gatagaaagt
    16441 gatgtgattg gtgatgtgtt ttctatccac ttcgaatggc tgttaaatac gcaacacggg
    16501 gcagattatt tcagaagatg gcatcgaaat aagcacaata gcggcgggct tcttgttcat
    16561 aaatctaccc atcattttga tctagtgaat ttttggttga acagccgtcc ccaaaaggta
    16621 tttgcattcg gtggattaaa cttttatggg atgcataatg cggagaaacg cggagtagaa
    16681 atattttaca gtcgatgcta tggaagcgaa ctagctaaag ctgatccatt tgctatagac
    16741 ctgtcagcca atgaggaatt gcgagaaatg tatttagaag cagaaaaaga cagtggatat
    16801 attcgtgacc gcagtgtatt ttccgatgat atctctattg aagatacact aggcgtaacg
    16861 gtcaaatatg aaactggtgc gattttgacg tattcgctaa acgcgtatat gccgtgggaa
    16921 ggattcaatg tttctttcaa tggcagcaaa ggacggatcg aaatgaaagt gatcgaaaag
    16981 tcttacatca atgcaggtgg agataaaaag gatgaaggag cagccgttct tcagtccatc
    17041 catgtctatc cgatgttcgg tgagccatat gaggtaatcg tcgaacaaga agcgggcgga
    17101 catggcggag gagatccgcg tttattagat gatctatttg gtgaagaaaa agaagaagat
    17161 ccgtggaatc gggcagcaac tcacgtagat ggtattttgt cgattttgac aggaatcgca
    17221 gcaaatcatt ctattgcttc aggaaaagca gtagtgattg acgagcttgt cagcttaaaa
    17281 gaataagaat agatttacgg aaattacttc ccgtagttta taaaatcttg ccttattgcc
    17341 gataggctgt cttttgaaca ctatttattc ggaaaaaggg gctatgacat gctttttgtc
    17401 atgccttctt tttatgtggg ctgctttttt agataggaga aaataaaaat aactatttaa
    17461 acccgaacaa aaaggaataa tgcattaaaa atcattagat tttacaaaaa aataagtaaa
    17521 ccacgttgtc agtttcagaa agtagtgtta gactgttttc aatatttgaa acaacatttt
    17581 ttattcaaat atggcaaact gccttcacgt gcaaaacagt tgcaagaaaa tgaatttaca
    17641 ctattattag ttttacatac ctacttatat atcgtcataa tatggatgac agtttctagc
    17701 cagtaccgta aatgctggac tataagtaaa agattggcta tttcaccctt cttttcttat
    17761 gataaagtgg agggtgtttt tctttaacag aaacatagta ggtttttgca caaaagcggt
    17821 tatttcggta ttaataaatg ataaaggagc aaataaagtg aaagaattag ttgaacgtat
    17881 tcaaaaagac ggacgtatat taggcgaggg cgtattaaaa gtcgacagct tcgtcactca
    17941 ccaagtagac cctgtattga tggaacaaat gggaaaacgg tttgcagaag tatttaaaga
    18001 acaaggaatc acgaaagttg tgaccattga agcttctggg atcgcaccag ctttatttgc
    18061 tgcaagagaa ttagatgttc caatgatctt cgctagaaaa gcaaaaagtt tgacgatgga
    18121 tgaagaatta ttgacagctt ctgtttattc ttttacgaaa caagtgacaa gtacgatttc
    18181 tatttctcgt aaatttttat cttcagaaga caaagtattg attatcgacg atttcttggc
    18241 aaacggacaa gcggcaaaag gattgatcga attatgccag caagctggag cgcaagtaga
    18301 aggaatcggg atcgtcatcg aaaagtcttt ccaagatgga cgtcagttac ttgaagaaat
    18361 gggattgaga gtcgtttctc ttgcgcgtat tgcttccttg acgaatggac aagttgagtt
    18421 tcttgaggag gacgcataat cgtggaaaaa gaaacacaaa atggaaaagc tgcggtttta
    18481 gggctgcagc atctgctagc gatgtatgca ggagcagtag cggtgcctct tttgatcggt
    18541 acaggactag gctttaatca agaacagatg acttatttga tttcaattga tatctttatg
    18601 tgtggattag cgacattatt gcaattgaca gttaaccgat ttttcggaat tggcttgcct
    18661 gtcgttttag gatgtgcgat ccaagcagta gctccactga tcttgatcgg aaccaatgaa
    18721 ggagtaggag ctatctacgg atctattatc gcttctggga tctttgttgt gttagtttct
    18781 ggtgtctttt ctaaaattaa aaaactattc cctcctatag taacaggaac ggttatcacc
    18841 gttattggtt tgactttgat tcctgtagca atcgagaaaa tgggtggagg taatgcaaca
    18901 gcagctgatt ttggtgacaa aacaaatctg ctacttgcat ttgtgacgat tctcctaatt
    18961 gtaggcgtgc aaatgctggc aaaagggttc attcgttcaa tcgcggtatt gattggttta
    19021 gtcggaggaa gcatcttagc tgctttcatg ggaatgattg atctgagcgc gattggagat
    19081 gcgccgttgt tccatgttcc acaacccttt tattttggta aaccaacttt cgacgtatgg
    19141 tcgattttac taatgatcat catttccatg gtcagcatgg tagaatcaac aggtgtatat
    19201 tttgcacttg gtgacattac tgggaaaaat gttggagaag aagaattgaa aaagggatat
    19261 cgtgcagaag gacttgccgt tatcttaggc ggtattttca atacattccc ttatactggc
    19321 ttttctcaaa atgtcggatt ggttcaactt tcgggaatca aaacaagaaa acccatctat
    19381 ttctctgcat tcttcttgat tgttttagga ttattcccta aaatcggtgc gttagcacaa
    19441 atcatccctg agccggtact tggtggagga atgttagtca tgttcgggat ggtggcagtc
    19501 caaggaatcc gtatgctgtt ggaagttgat ttcagcaatg ataaaaatct attgattgtt
    19561 gctgtttctg ttggatttgg gctgggtttc aatgttacgc cgacattatt cagtcaaatg
    19621 ccgcaaacat tgcaaatgtt cactggaaat ggcatcgtaa tgagtagcat tacggctatc
    19681 atattgaatt tgatctttaa tggattgaaa aaagatgaag aaatattgga agaagccttc
    19741 aagaagtaat agagcaaaag aaaggttgtg aaatcagcgt tttgacctga ttgttagaga
    19801 aacaaacgga aaaatagttc ctcgtatttt gccgtttgtt tgagctaata ccgagggtca
    19861 gctgattgaa caccgttgaa ggaagaggtc gtgagcctgc cgttcatctc cgagtcacaa
    19921 ggaacaattt caaaaaaaag cttctcatgt ttgttgaata ttgttccttg tgaccgagga
    19981 gttggcagga gaacaccgtt tatccataaa aaggaatgtg acctaacttt tgtcacattc
    20041 ctttttttta tctttaataa acacgaacaa taaaatgttt ttctttgtta acattcgaaa
    20101 tttctttgac atcaaaaaaa gtgattgtta aaatatgaat gtagaaaaac tgggaggaaa
    20161 aacaatgaca gcaaaaatct ctgtgattat ggggagtact tcagattggg aaacaatgaa
    20221 agaagcatgt caaatattgg atgaattcgg tgtgtcttat gaaaaaaagg tcgtttctgc
    20281 tcatcgaacc ccagatttga tgtttgaata tgcacaaaac gctcgaaaaa aaggaatcaa
    20341 aatcattatt gcaggagcag ggggagccgc gcatctgccg ggtatggtcg catcaaaaac
    20401 aactttgccg gttatcggtg taccggtcca atcacgaaca ttaaatggtt tggattcgct
    20461 tctttcgatt gtccaaatgc ctggaggagt acctgtagct actacagcaa tcggaaaagc
    20521 gggagcaatt aatgctggac tacttgcgat acagatgctt tccatgtatg atttagaatt
    20581 ggaggctaaa ttggctgaaa gacgttcaat gttggctaaa actgttatag aaagtagtga
    20641 tcaacttggt taaacctttg ttgcctggtt caacgatcgg gatcgtcggt ggcggtcaat
    20701 taggtcgtat gatggcgatt agtgcaaaag aaatgggctt taaagtaggt gtgctggatc
    20761 ctgtgagcga ttgtccagcc gcacaagttg cagattggca cattgaaagt gtctatgatg
    20821 acacctttgc gctgaaagag cttgccagaa gaacagatgt cattacctat gaattcgaaa
    20881 acgtcagtgt agaggcgtta aatgcgattt tacccatgtc atttattcct caagggacag
    20941 acttgcttgc gattacgcaa gaccgcctgt tagaaaaatc ttttttggaa acgaataaca
    21001 tcgtgattgc tccttatgca acgatcgtca gtccgacgga tatccaagat gcgattgacg
    21061 ggatcggcta tccttgtgtt ttgaaaacca ctcgaggcgg ctatgatggc aaggggcagt
    21121 atgttttgaa aagtcgggcg gatctagctc ctgccatgga ccttttaaga gaaggaacct
    21181 gtgttttaga agcatggatc ccgtttgaaa aagagatttc gatcatggtg gcaggaaatg
    21241 gtcaaggaga tttcacgact tttccggtcg tggaaaacat ccaccacaac aatattcttc
    21301 atgaaacgat tgctccagcc gcgattgatc aggatgtgat cgaggaggct gagcgtattg
    21361 cccgtgtgat tgcagaagca gtgagccttt caggtgtttt aggggtagaa atgtttttaa
    21421 caaaaacagg cgggctatat gtgaatgaat tagctcctcg tcctcacaat tctggacatt
    21481 attctattga agcttgttct atgagtcagt tcgatgccca tattcgaggt atttgtggtt
    21541 ggccattagg agaaaaagta cgtttgataa gcaatgcagt aatggtcaat gttttgggag
    21601 aacaactgct ggaaagctat cgcttgattg agaataagcc agactggcaa ttccatttct
    21661 atggaaaaaa acaagcaaaa aaaggtcgca agatgggaca tatcactatc ttgacagaag
    21721 acatccagca aacgctggaa gaaatcaaac aaacgaatat ttgggattag aggagaaaaa
    21781 acatgttaga acgttataca cgccctgaaa tggggaatat ctggacggaa gagaacaaat
    21841 accgtgcgtg gctcgaagtc gagattttag cagatgaagc ttgggcagaa cttggtgaaa
    21901 tcccgcaaga agatgtgaaa aaaattcgtg agcatgcatc atttgatatc gatcggatct
    21961 tggaaatcga aaaattaaca cgccatgatg tcgttgcgtt tacacgagcg gtttctgaaa
    22021 cattgggaga agaaagaaaa tgggtccatt atggtctaac aagtacggat gtcgtagata
    22081 ctgcttatgg ctatctcatc aagcaagcaa atgatatttt acgggaagac ttgaaacgtt
    22141 ttacggaaat cattggcgaa aaagcaaaag aacacaaata tacagtgatg atgggtcgga
    22201 cacacggtgt ccatgctgaa ccaactactt ttggattgaa acttgccaca tggtattcag
    22261 aaatgaaacg gaacatcgaa cgatttgaac atgcggcaaa aggagtagaa gcaggaaaaa
    22321 tctcaggagc agtgggaacg ttcgcaaata tcccgccatt tattgaagag tatgtatgta
    22381 aacaattggg gatccgtcca caagaaatct ctactcaagt tctccctcgg gatctacatg
    22441 ctgaatattt ctcagcgatg gcgcttattg ctacaagtat tgaacgtttt gcaacagaga
    22501 tacgcggatt gcaaaaatcc gaaacacgtg aagtagaaga attttttgcg aaaggtcaaa
    22561 aaggttcttc tgctatgccg cacaaaagga atccgatcgg ttcagaaaat atggctggtc
    22621 tagccagagt ggtgcgcgga cacatggtca ctgcctatga aaatgtcaca ttatggcatg
    22681 aaagagatat ttctcattct tcagcagaac gaatcatctt gcctgatacc acgattttat
    22741 tgaattacat gttaaatcgt tttggcaata tcgttaaaaa tctaacggtc tttcctgaaa
    22801 acatgaagcg gaatatgtct gcaacatttg gtttgattta tagccagcgc gttatgctga
    22861 aattgatcga taagggaatg acaagagaag aagcttatga tcttgttcag ccaaaaactg
    22921 cgtacgcttg ggacaaccaa gtgcagttcc gcccgctgtt agaagaagat ccaaccatca
    22981 catcggtatt atctaaagaa gaaatagacg atgcctttga ttatcatcat catttgaaaa
    23041 acgttgacgt gatattcaaa cgagtaggtt tggaataaag aagagtgagt tgcaaaattc
    23101 aattaaaata gaatagcaaa aataac
//
LOCUS       DAFKHN010000045        22028 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFKHN010000045 DAFKHN010000000
VERSION     DAFKHN010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22028
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.045"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(60..1370)
                     /locus_tag="LY912_001716"
     CDS             complement(60..1370)
                     /locus_tag="LY912_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBM6955399.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1382..2800)
                     /locus_tag="LY912_001717"
     CDS             complement(1382..2800)
                     /locus_tag="LY912_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6955400.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3040..4608)
                     /locus_tag="LY912_001718"
     CDS             complement(3040..4608)
                     /locus_tag="LY912_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBM6955401.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4612..4893)
                     /locus_tag="LY912_001719"
     CDS             complement(4612..4893)
                     /locus_tag="LY912_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBM6955402.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4890..5813)
                     /locus_tag="LY912_001720"
     CDS             complement(4890..5813)
                     /locus_tag="LY912_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBM6955403.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5810..6688)
                     /locus_tag="LY912_001721"
     CDS             complement(5810..6688)
                     /locus_tag="LY912_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBM6955404.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6675..8012)
                     /locus_tag="LY912_001722"
     CDS             complement(6675..8012)
                     /locus_tag="LY912_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBM6955405.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8015..9118)
                     /locus_tag="LY912_001723"
     CDS             complement(8015..9118)
                     /locus_tag="LY912_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBM6955406.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9192..10700)
                     /locus_tag="LY912_001724"
     CDS             complement(9192..10700)
                     /locus_tag="LY912_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBM6955407.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10666..11358)
                     /locus_tag="LY912_001725"
     CDS             complement(10666..11358)
                     /locus_tag="LY912_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBM6955408.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11380..12354)
                     /locus_tag="LY912_001726"
     CDS             complement(11380..12354)
                     /locus_tag="LY912_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6955409.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12654..13526
                     /locus_tag="LY912_001727"
     CDS             12654..13526
                     /locus_tag="LY912_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6955410.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14108..16306)
                     /locus_tag="LY912_001728"
     CDS             complement(14108..16306)
                     /locus_tag="LY912_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955411.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16538..17530
                     /locus_tag="LY912_001729"
     CDS             16538..17530
                     /locus_tag="LY912_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6955412.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17590..19011
                     /locus_tag="LY912_001730"
     CDS             17590..19011
                     /locus_tag="LY912_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBM6955413.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19004..20503
                     /locus_tag="LY912_001731"
     CDS             19004..20503
                     /locus_tag="LY912_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBM6955414.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20542..21936
                     /gene="uxaC"
                     /locus_tag="LY912_001732"
     CDS             20542..21936
                     /gene="uxaC"
                     /locus_tag="LY912_001732"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBM6955415.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6669 a         4494 c         3823 g         7042 t
ORIGIN      
        1 tcattaaaaa aaataaaggt caagctaaaa tattatttaa gcttgacctt attataattt
       61 caacgattgt caaaagtatt gtttgcagct gtgttgccag tttctataga taaatcacag
      121 cttttgaaac ataagttttg tactgcttcg attcgcccga attcttttgc agttatttgg
      181 caatgagaaa agcagacatc ttctataggc ttttcaggaa atgctactaa atcaaaagct
      241 cgggaaggaa gtgagtaacc tggagaaagg catgcctgta cgtttttgat gtgtatgtct
      301 ttgactttcg tcatttgctt tgattcaggt atttcttcag ccactgcttg ccaactttct
      361 ggcatttgag caaggtcatt gctatttttt ctattgtatt cattatgcca gtccattatc
      421 caagaaaaag gaaattgtac atcaatcata ttcagatttt ctaccctgat attttcgatc
      481 actccccctc tttcttttga agatttcatt cgaataccac agtctgactg aaaaaaattg
      541 atatcgtgaa tatatacgtc actaactcca gcactaactt cgctaccaat agttacaccg
      601 tatcctgaac ggattttaca tctagcaacc tcgattcttg atgattttcg attgactctt
      661 gcaccattgc catctctgcc agacttaata gcaatacaat catcaccaca ggccaaatca
      721 cattcataga cacgcacatt tgttgaagaa tcaatatcaa tcccatctgt acttggtcca
      781 tcattgttgc ggatgattac tttttctact aatacatcgt tagaataagt gatttgcaag
      841 ttccaaaaac ctgatttctg aaaaatcaaa tcacgaacaa caacatgttc tgcatgatac
      901 agtaaacaag cgcgtggacg tttaatagca taatccgcaa tccaacgaag tcccttttga
      961 tcgtattcag ctcttgtccc gcttttttga tcttttcccc aatacagctc ccaccaatgg
     1021 tctccttgac cgtcgattat tccttttcct tctataagaa tatctttcgc cgagagaaca
     1081 ttcaaaatcg ctgctggcca tttcatttct acgccggcta ctcgtgtatc gatttctgga
     1141 aatgcttcga tatctgttct ccccttgagg actgcacctt cttcaaagat aagatgactc
     1201 ttatctttta aaaaaagggc tccgactaaa taaatgcctt ttggaataaa tacaggtaag
     1261 tgttctttcg caccttgatc gattgctttt tgcagtatta ttgtatcatc ttgttgagtg
     1321 tcgtttgttt taaagttcaa agcattgata atcccttttt ttgtccgcaa tacgtttctc
     1381 cctatctttc attgattttt ttcaattctt caccaataaa tacagttttt gaacgattca
     1441 gtgggtaacc tactagcaaa atgattgcgg atacaaataa gcagaatgct ggtaacaagt
     1501 ttgccatcgt ataaatcctt tcttgtacta aaactgattg gatggctcca cctgttgtag
     1561 acgattggta accaatgagt gccagcataa atccgcctac cgctcctgca catgcttgtc
     1621 ctacttttct cgcaaaagaa tttactccat atactgttcc atcttctctt aagcctgtct
     1681 tatattgatg ataatcaatc acgtcagtaa tgaatgccca gaccatcaaa ttgaataaac
     1741 cagatcctaa agtagcgata aataaaagaa tcagatatac ccatgcattt gttatatgaa
     1801 ggaaatacat cagcaagtac atacatgaag aagcaagtaa cgcaaatacg cttgcttcct
     1861 ttttaccaaa taattttgtc agctttgtag caaatggtgc taaaactact actgttccgt
     1921 aagtaaataa aagagcaaca gacattgctt gtttattatg gaagtaatca ttgaataaat
     1981 aagtcatatt cgtcccagct aaaatctgat tgatcacaat gaaaatgtca acaatgacta
     2041 aaataatcag tgctcgatta gctaacaaac cttttaccaa ctgagaagca gatacttttt
     2101 cgtttttgac aactcttact ctttcagtag tcaatttaca agttaacata tatgcgacaa
     2161 atgctattgc agcacatccg attgaaatcc aaaagaaatg attccctgaa acgacttgtt
     2221 gtccactctt gttatgggta tacattaaaa tcggaatgaa gaatcctgta gttgatccgc
     2281 caatcgcaga accaatgctt cggaacgtgg acaacgaggt gcggtcatta ggatttgagc
     2341 taattgctgc tgccattgct ccatacggga tattgattgt tgagagaaaa atcccataaa
     2401 caatgtatga aacaaaaata taagcaatct tcaccgtcat tggaagatgt tggacgaatg
     2461 gcaaaaacaa aatgacagtc actaagcaaa atggatactt catttttctg atccaaggaa
     2521 taaatcggcc agtttctgtt aactctgaga catcacataa tcttccaacc atcacatcag
     2581 caaacgcatc caaaattctc gaaatcaaga ataacgtacc tacgattgcc cctgaaacgc
     2641 caagaacatt cgtataataa atcatcaaga aactattgac taaacctaaa ataaaacagt
     2701 tacctagatc accgaacatg tagcctatct tatcggaaat cccaaattcc tttttttctt
     2761 tttttactgt atttgctgta acagcatttt gtgaaagcat ttgaattcct cctacctctt
     2821 ctagtaaacg ttttcaaaat tataactctt tttttcttgt ttttatattc acaatgttgg
     2881 ctttttattg cattatcttg acagataaaa aacaaaaaat aatctaaaaa cattgatgca
     2941 taagattgat aacttttttt acataacaat atatacaaac aaaaaaattc actaactagt
     3001 gaaaataagt tagtgaacct catttattaa agaattaaat tacagatgat cttttccatc
     3061 atacttgaaa aactcaaaat cagcataact tcctcttttt ttatttagat catgcactgc
     3121 tatcccgata aaatttccag taaaccctcc tgagagtata cacatgtttt tttgcggacc
     3181 tactttcttc cattcttcag ttgatacgtc tttcaaatga aactgtgctg tctctttctt
     3241 tacagtgact ttcaaaaaag tcttcttttc tgtgagtgga atcgtccaat cttctatttg
     3301 tgctactccg ttttctgatt ctatcatacg taggcatttt cccttgtcct cattccaagt
     3361 aacataacaa taaatataat tggattcatt taagtacagt accagtccag ccatctgatt
     3421 aaaattatta ggcatgtatt caaatgctgt ctccgcatca aaagtaaaat ccgtttgccg
     3481 aatagctaac aaatgatgtt cgaaggtaga ttgaagagat tcaccggaaa tcagacgtaa
     3541 aaaacctggt ctacattttg tatcacacca atcagcattt ggcaaaatgc gtctggcatt
     3601 ccagttcttc tttagctctc cttcaaatgt atccataaac tgatgatctt tttcttgttg
     3661 tacctcttca tttgtctcaa tcattatttc ttccatcgga gttgtctggc tatctttaag
     3721 tcttaaccaa tcgtcggacg tccaatacac ttcttgaata gcggtttctc ttcccaaaat
     3781 agccgcaccg tttaatggtc tggtacaaag atatgtcatg taccatcttc ctgacggggt
     3841 ttgtactaag ctcccatgtc ctgtacattg caatgtagaa gcaggtttgt cactagctgt
     3901 cagcatagga aaaccaggat caagctcgta aggaccagta atattctttg ctcggcaaac
     3961 tgtaactgaa tgtcctcttc ctgtaccgcc ttctgccgtc atcaaataat aatacccgtt
     4021 acgaaaatac aaatgtggtg cctccgtttt cgctaattct gtacctgcaa atattttata
     4081 gatgggacca tcaagcttct tcttctctgc atcatattct tgtaatacga taccgctgga
     4141 tttattcggt gtgtccagac gataatccca tagttcattg acaagccatt tttttcccgt
     4201 ttcaagatca tggaacaaag aaggatcaaa gccgttacta tttaaataaa ttggttcgga
     4261 ccaaggacct gtgatctcag atgcagtgat caaataattg tggacatctt taaacggacg
     4321 gcctgcactt ttgacatctg tgtaaacaag ataaaacaat ccatcagcat aactgatctg
     4381 tggcgcccat atacttccat ttgtaggatt tccttgcaaa gatacttgag tggtcaaaat
     4441 atccgttgta tgtgaccagt tgactaaatt tttcgactca tatactcgga ttcctggaag
     4501 ccattcaaaa gaggagacaa taatgtaata ccgctctttc actcttaata tattaggatc
     4561 tggattgaat cctcttaaaa taggattttt cactttgata gtctgcatga ttcaggctcc
     4621 ttttctcatt cttactcgat ataaactgaa tgccccagct gctaaaaaag caagtgaaat
     4681 aaacaacaca acggcaaaca gaccagtcat gtcctgtaat aatccaaatg tattttctaa
     4741 agacaaagtt gaatgatcta cagcaagcga ctgataactt tttttaaact ctgacgcaga
     4801 catattactt aaagtaactg ctaacccgcc aaagaaaatc aaagatagac tgccaccgac
     4861 cattcctagc aatagttccc attttctttt catttctgaa ccccctgctt ttctaaatgt
     4921 atccattcag gtcttttgat cgatgtttca taattgttat tacgttcaga gaatttgaca
     4981 gtctgttcat ttttcttgtc atcccaatta tcccaaccag ttgggtgaac atgcccacct
     5041 atcttacacg cttcaaataa gacatttgca tacggacgcc acggtcttcc taaatagacg
     5101 tttctagtat caggttctgc agtcaaggta cagctttcaa aacgataccc tgttttttga
     5161 tttttcggcg tagatgctgc tgtgatgtat ccaggatttt tactggctaa gctatggata
     5221 tgacactgat gaaaaacggc atctgcccca ccaaatatga aatccaccgt tccttcaatc
     5281 cagcaatatt cataggtctg acgacaatac tcaggattgg cagaagccgg tgtacaaaaa
     5341 ggagtaccat ctttttgcaa atcaggcaac ggacccgtgc ataaggtatc ctgataacca
     5401 gatagtcgac agttttttaa agatacgcga tctcctgaat tgaataaagc aacagcctgt
     5461 cctacctttt ctcctggacc tgctgtattt tcgatgtgaa gattttctaa tacgacattc
     5521 gatccttcta agaaaaaagt agcacttcgg aaagtcccta actggctacc gtcaagatac
     5581 tcctgttttg caaaacgatt accggagata actactgttc ctgctcccac aagtttaaaa
     5641 ttggataatc tgctttctat atattcatca tatcttcctt cttttactat caagaccttt
     5701 ggatggctat ccggcaggcc tgccaaataa tcgattcctt cttggatagt ttcaaaatcc
     5761 gtcggggtat ctatagcatt ctttccaatt atcagtttgt ctttcatcct cataaatgct
     5821 cccttatgaa ttgtttccaa atatttctca tttcttgtgt ttccatatga ccgcctgtta
     5881 aagaaaaaga agaaaagttt tctggactac ccattgattg atactttttg tccagccctt
     5941 ttctcagctt cagtacgcct tcgtccaagc acatcgtatc gttttttcca actaagctaa
     6001 gacgagggcg cggagcgatt ttttcttgga ttgctaacgt tgtataagct gtcaatagat
     6061 ttggcacata gtaataaaac ccatgatgat ctaggcggcg atgtagcaaa agtgtttcga
     6121 tgtccacctg tgccgctaga tcaatacaaa ctttgacacg agaatccaat gctgtcaccc
     6181 accagcttaa taagcctccc atagaaagac caatcgttgc gagccgttga gtatctgtgt
     6241 cttcccttgt ctccaaataa tcgatcaagc tgatcacatc ataaatacgc attccccata
     6301 acgtttttcc tgttaataaa aattgtttga acaactcgct ttcagaaata cctccgcgtt
     6361 cttcaaatcc ccaagcatca atcgaccaaa cagcatatcc cattcctgtc agtacttctg
     6421 caaaagatgg agaagctaag taaggagcac catggatcaa ttcacttttc ccgactgaaa
     6481 aatctccgcc gtgagaatgc aggtaaagga ccgtcggaaa cggtccttct ttttctggat
     6541 aagcatagag ggctggtact gtttccaatt catttaagta caattgatag tattcaagca
     6601 taaaaccgtt ttgtttttct cggtataatc gttttccact aggggtatgt ctgctagatg
     6661 gagcacctaa aaaatcattc aactgcataa gcaaagtttt tacgaacaac cagttcatcc
     6721 atattttctg attgatttga ttggaatttc tcaatactga tttctttagt attttctaat
     6781 agaaatgctg gtccctcgtg attttcaatc gacatctggt taaaggaaac cttacccgca
     6841 aagccaatat aaaatccttg tctgctcatt tcctctattc ctgtcatcat agcaggaaca
     6901 ccgggaactg catcttgggc catcgagaca tcgatattgt caaatgtgat ttcttgtatg
     6961 aattgttccg ctaatccata aataaaacct gcagaagcat ggacattcct tgccgtgata
     7021 ttcgaaaaat ggatccttct gaatgctgat gtccgttcat ctatcggata agcctttttt
     7081 tcccatacat acggttcttt ccctcgcgga ccacagaaat aataaagatt cagtataaat
     7141 ggacacatca cattatccat gactatattg gatactcgaa tatcttcaac gatcccgcct
     7201 cgacctcgtc tagatttcaa tcgtattcct cgatcagttt cttggaagat acaatttgaa
     7261 atggtaatat tacgaatact accactcatt tcacttccta atacgacacc gccatgtcca
     7321 tggaccatcg tgcaatttgt gatcgtgata ttttcgcaag cgatcctttc gtacgtatct
     7381 tcagtccctg ccttgattgc aatacagtca tctcccacgt caatatggca attactaata
     7441 cgcacatttt tgcatgattc tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc
     7501 aagatcgtca agttatcaaa cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt
     7561 ggtgactgga tcaatttaat atctttcaca gtaattcgat gacagttatg gaaactcatc
     7621 aatttaggac gaggataagc gagattatct ggttcatttc taaaagtatg ccaccatttt
     7681 tttccatttc catctaatgt accgaaacca gtgacagaga tgttctctac attttgagca
     7741 tagatacagg aagcataaac ttttcgatgg actccttccc aacgtgaatg aacaacagga
     7801 taatcttttg gatcgtcaga gaatttcaga accgctcctg cgcttaaatg aagttcgaca
     7861 ttgcttttta aaaataaagc tcctgttaga aattcacctg ctggaacaac tacggtcccg
     7921 cctccgtcac ttgctgcagc atcaatggct tgttgtattg cttcagtatt caattcatca
     7981 attgatgcgc caaatgtcaa aatatcatac atatttataa tgcctccact tcaatcaatg
     8041 cttgcaagaa tgcaccaacg cctttttgat cattacaaat aattggttca ctgatgtagt
     8101 aagcatatga accatctcgc tgatctgctc cgcctaaccc tgctacttga cagtttttat
     8161 tcaagttcag ccagccttct tttgtttcca gaacaaattc atcaagtaat ccttgatgtg
     8221 atttcttcac ttgtggaagc cattcttctt tgttcagcag tcccaaacgt attcctttag
     8281 ccattgcgta aacaaacata ctactgccgg aagcttccag ataatttcct ttccgttttg
     8341 tttctgttgt tacttgatac catgtcccgc tgttttcttc ttgatatgga agtaatgcag
     8401 ccagtgtctt ttctagaatt tctttcagca aagaacaatc tgtttcttca tgaagtaatt
     8461 cataggtatc tgctgcagcc atcaaatacc agccaatcga tcggctccaa aaatgatggg
     8521 atagacctgt ttttggatca gcccatggtt ggaccttctt ttcatcccat gcatgaatca
     8581 gcaaatttgt ttttggatcg aatagatgtt tataactgat ttcaaactgt ctcaaaacat
     8641 cttggtaatc tttttcttca ctaaaattct ggataaattc agcataaaaa ggagaaccca
     8701 tatataagcc atccaaccaa atttgataag gataaatttc tttatgccaa aaagctcctt
     8761 cggatgtgcg tggatggttt gccaactgct gggaaaggag ttctgctgct tttttatatt
     8821 tttcttcgcc tgtttctttg tacaataaaa agaaaagctt tcctgtattt acatggtcga
     8881 tattgtattc ttcaacgctg tagccacgga tcgttccatc ttcttgcacg aaatagtcga
     8941 tattgtcttt tatgaaatca aaataaattt tttcttgggt tcgttcccaa agtaattgga
     9001 accctttaag tacgacgcca tagtcataag accattttcc tttataccac ttttcttcat
     9061 ataagcgagg tgttctttcc atgatacttt ttgctaattt ctttgaccag ttttccatta
     9121 tttgctctcc tttaaaaatt aaaataggat ttgggacaaa taccaagaag tatttgtccc
     9181 aatcgtctat attactgtgc cgctgctttg tatgcttcct cgtactcttg tgtgattcga
     9241 tcgcctcctt gtgctttcca gtcttctaca gcttttttga atccatcttc gtcaagctgt
     9301 cccatgatgt attgcaccgt agcatcaatg acgatttttt caatttctga tcctacttca
     9361 ttgttcgtcg gtgaatccaa tggcacagaa ggatccatta cagcaaattc ttcattttct
     9421 ttgatcaatt gattagagaa ttctttttca gggtctgtat ctttgaaaga gaacgtcact
     9481 tcactaggac gagagcttga taacggttgc acctcttgtt gccaaagatc catatcgata
     9541 aattcgatag aaccatcatc attcaattca taatgcgttc cttcgatacc gccagtcatc
     9601 aatttataca catcttcttc taaaagatca tcaacaaatt gaagtaattt cttcaattgt
     9661 gcttcgtctt ttacttgaga tttgggaaat gctagcaagc cgccaatacc atttccttct
     9721 gaccaaacat gataaccgcc gccttcacca tctgagatct tgtttacagg cactaattcc
     9781 atatcatctt gaataccttg acccatcgtc ttcagattct tgatatccac cattccagtg
     9841 tagattccag ttcttccttg tgcaaattgt tcttgctgat cagtcttttg ggtaactgca
     9901 aagtcttgtg ccaaatagcc attctcaaat agatctcttg aaaaattcaa agctttcata
     9961 tactcttctg tatcaaattc tggagtgaat ttgccattat cgtctacagc ccagccattt
    10021 ggtgctccaa aataagaagt gaaaagttta aagctggtat aacgaatatc actaggcgca
    10081 cgatcgccaa aaccaactgt gtcgtccaca ccatttccat caggatcgtt ttctgtaaat
    10141 tgtttagcta cttcataaag ctcatccatg gtagttggaa catctagtcc tagattatcc
    10201 aaccagtctt ttcgaatgac taagccagca cgagcgtagt ctttttgtat cggtacgccg
    10261 tacaaggcac cgtcgatact cgcagcttcg attctatctt cagaaatttg acttaaattt
    10321 ttatagtctt ttaaatattc tgatacatcc cagaatacgc ctgattttaa cgcattgcgg
    10381 acagaagagt ttttcaacat cgcaatttga agtgtaacga tatctcctag ttcatcagaa
    10441 gccaatgcag ttgttaatct ttcttctttt gaagcatcag gaatccagtt gaatgtcagt
    10501 tccgtatcgg ttttttcttc gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga
    10561 tgcaaaatat ttaaccaagt gattttagct tttccatctt ctgtctctga agaactgtta
    10621 cttgaactgc tgccgcatgc ggcaagtgct agaattcctg caaaactaag acctaatttt
    10681 acgagcgttg cttttttcat aaattttctc cttcactgtt ttaataatat ttttgttttc
    10741 ttctgttttt tctgtatatg agttcttcca ttccaaatgg caaaatatag aatttgctgt
    10801 ccacgtgact gcggaaaaga agagactgcc accgataaag gttaaaacac ctggcattgt
    10861 ttggatgatc atcagataaa tccctaccat acttaatatc aacactaatg agtaatgaag
    10921 atgtgagaat ccgaataaaa atgccatttt cattttgaaa aaatatcctt tccaatcata
    10981 atgagccatg attgggaaaa tatagagtgc tgagagcaca tatatgaacg cagcaatata
    11041 caaagcgatc ctaagatacc aattgtgtat gaaagaaaga tccacaagta aaacaatccc
    11101 gatggcgcca tatatccagc tcatcagcaa ggtttcacga tagttttctt taaaatatgt
    11161 gaagtacgtt ttcgtcaaag gaaacgtttc ttttgagcgc agccattttc taatcactgc
    11221 aaccatcgca tacgatgcag gaccgaaagt aaaaactccc aaacctgcga tgactaaacc
    11281 gccccacaga aaattcaaat aaaccaactg taaaatacga tttagccttc cgtttatttt
    11341 atctaatgac tgcagcatat ctttccctct ctttctatct tagtaaacgc cgtcttctcc
    11401 tagctttttg gcaatcttat tagctaaaat taccataaac aatcctacga cccctttaaa
    11461 caatcccatt gctgtactga aacttaactg tccattcttc aatccagctg tataaatata
    11521 ggtgtcgaaa atttctgcaa cgcttcgatt caatgaattc aataacaagt acatatgctc
    11581 gaaccctaag tctaatgtct gaccgatttt tagaatcagc aaggtaatga ttactggacg
    11641 aattgccggc aatgtaacat gccatgtttt gcgtaagcgt cctgctccat ccatttctgc
    11701 agcttcatac aactgtgtat cgactgcagt tatcgctgaa aggtagatga tcgtagacca
    11761 gcccaactct ttccagatca cttgtccgat atatactgtg cgtgtccatt caggggatgt
    11821 tagaaaactg attttttcaa atcccattgt tgcaaggaat tcattcaata cccctccgtc
    11881 aacattcaaa aatacataag taatcgaaac aatgattacc caagacatga agtgagggat
    11941 gtaaatgatc gtttgaatcc cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa
    12001 agacaaaatg attggcatcg gaaaaaacac gaagatattt aatccgaaca agatcaacgt
    12061 atttcttaat aatgtaaaga atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc
    12121 gacccaagga cttcccatta ttcctaaaaa tggttgataa tcttgaaaag caataacgag
    12181 tccccccata ggaagatacc taaaaatcaa gaaataaagg actcccggca gaatcatcac
    12241 atataaaaat ttattcgttt tgattcctgc aattattttt tttcgtcttc tgagcttttc
    12301 ttcttttttc gatagcgtca gttgaaatgg ttcttgtttc tttacacttt ccataagccc
    12361 ctccttagtt ttgtgaatgt ttgctgctta tgacttcatg atagataact atctgaatta
    12421 cgtatataat catttttatc gtaagtaaaa acgcttacat agcaatgatt tttgtgctat
    12481 acaaaacgat aaagtgtatt ttttcacaaa taaactacgc atagcaaacc ttctattttt
    12541 ttctatctga cacttagcat aggaaatgat tatatacgta atctttcacc gatgataaat
    12601 tgaacatata gaaacagaaa catttaattt attttgagga ggagcctatc tatatgaaaa
    12661 agaaagtctc tataggagaa agaagtttta cacttttcaa caatacgttt ctaattttgc
    12721 tagctttgat ctgtatcgtt ccttttttaa atatcatcgc tacatctttt gcttctacac
    12781 aagaagtcgt cgcgaaaaag tttatccttt ttcctactac cttttcttta gacgcgtatc
    12841 gctacattct ttctacgccg accattttta gagcacttgc tgtttcgatt ggtgttacag
    12901 gtgtcggaac gatcgtcagt atgtgtgcaa cttcactgat ggcctacggt ctttccagaa
    12961 agtatttgtt tggtcgaggt ttcgtcaact ttcttgttgt attttctatg ttgttcagcg
    13021 gggggatgat tccaacgttc ttagttgttc gttctctagg gctggtcaat tcttactggg
    13081 ccatgatcct gcctgtggct gttaatgcaa tgaatatgat cattatgaga aactttttcc
    13141 aagccttgcc ggatagtttg gaagaatcag caaaaatgga tggttgcaca gattttggtg
    13201 tatttttcaa aattatgctg ccattagctt taccgtctat tgctactatc tcgctttttt
    13261 atgctgttac ttactggaac acttatatga ctgctatttt gtatatcaac gattcatcta
    13321 aatggccgat acagattctt ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag
    13381 aaagtagtgc cgttgatgtg attccaccag cacaaacagt taaaatggct gttatcgtta
    13441 ttgcaacagt gcctatgctg attgtttatc cttttgttca gaaatatttt gtcaaaggag
    13501 cactcgtagg ttctgtcaaa gggtgattat gtactgaacg caaaatggta gttgtgtcag
    13561 aagtggtcag cttcaagaaa taagaaggca tttacgaaaa ttgcttctta aatttttgtg
    13621 aaatttcggc ttatttttcg aagaatctac tcctggaaca ccgtgtatca gaggttgtga
    13681 aagagacgtt cagccttgag cgatgataaa aactctcaca aacattgcga cgagtaaccc
    13741 acaggagcaa taagaagcga ttttgaaaaa tagcttccca tatttcacaa aattatgcct
    13801 tattgtcgat agcctgtctc ttgaacgcca tttattcgta aaaaagaact gtgacaagac
    13861 ttttgtcaca gttctttttg cgtgcttagc cttgaaattt aactatccat aaatacaaat
    13921 actagggtta ttctaacttc ttttattgct tgaatcagtc cacaagaaaa acagcctctt
    13981 gattaaacgg cgtttatctt gttgattctg cggcaataaa atcagccagc agcaaaacat
    14041 gaagtgctgt tttttgctgt cctcttttat tgcttgaatc agatcacaag aaaaacagcc
    14101 tcttgattca caaatatttt tttcgatatt ctcccggcgt aatcgattcc ttctttttaa
    14161 agaaacgaat aaaattttgc ggatttcgat attgcaatct ttctgcaatc tcttttacgg
    14221 agaggttagt ctctttcaac catttttttg ctacctctaa acgatgattt tgaacaaaat
    14281 caccaaattt ttctcctgtt tcctttttaa atacattact taaatagtta gggttataat
    14341 gcaacctatc agcgatcaca tctaaagaca gatcacgatc atattctgtg tagacgatat
    14401 gcataatatt ctccgacaaa tttttaaatt catgatcagt gattgcttga gagcattctg
    14461 tgattggcag aactaattgt tctaaaacaa gtttttctag ttctttggga tgataattgt
    14521 tcagtgcttt tacataaatt tgtttcatgt tatcaaagtt ttttgaatct actcccaata
    14581 actgtcctaa ttgaacgagt tcattgatca agcggaccga aactacttcc cgactcaaag
    14641 gatttttatt ttgtgcaaac aatgcatcaa tcaattcatg tactaaattc ttcacttcct
    14701 gatttccaga acgaatggct tcaaacaatc gattttgttc ttctatcgga tatctaataa
    14761 gtgttttttc atgagcagca ggaacgattt cctgataaaa aataattgaa cttggaccag
    14821 tatttacacg ataatacagg gcttcttttg cccgatcaac cgattgcttg ctttcattca
    14881 gcgtttcgaa ccggttactg atgcctatac tgatagttaa attcaagtat tcttttacac
    14941 gtttttgaat gagtcggcaa tactccatga cttttttgct tgcttctgca tcatctttat
    15001 ccattcgata aatagtggct tgcatttctt cattcaaaac gatcggcagc attcgatttt
    15061 cctttggcac aatttccgtg atcatgttgt tgatcgctaa aagtagcaaa tcacgctccc
    15121 caccgtgact atcttctaac agatcgattt gaaccaaagc tgtataatag cagtcatttt
    15181 gagaactata accaaattgc tgcaaccgct gatctagttc tcgcctttct actcgatttc
    15241 taaataaact aagtacaaat agcgtttcca gctgtggctt ttgggtaact aagtgtgcac
    15301 ttaacgcttc tttttctcct atgatccgac tgactgattg agcgaccaaa tctagttctt
    15361 tcccactgaa tccttttgat ttaagattca gacgttcctg tatttgagaa atcggacggg
    15421 caaatctgtc cgaaaataag taggaaaaaa gaccaatgag tcctaccagt gttaaagaca
    15481 ctgcaactag cccgattctc agattgcgga tcattgcgcc aattgcacta gagtcaactt
    15541 ctaatctgta aatccaatta ttataatctg atttcagtac tatatacgtt ttatcttttt
    15601 ctcttatcac tttcagctga ttgtaatcta gatccacgtc cgttaataca gttggttgct
    15661 ctttattttt tactgtctga gtagtaaaaa ggttgccaac ttcgttttca atagaaagta
    15721 tgtcttctcc actttcacca acaacttgtt ctattgtatg tttctctatc gtagcaattc
    15781 ccaatgcata tttttctttt tcaaacattg gcaaagaaat caccatttcg attcctttgt
    15841 ttttcttttg ccaaaataaa ttatttttgt tatttatgta cttctgttga tacttttcaa
    15901 cttcctcttc ggtcagttga ctcaacgatc cattgattac tccccattta ccagccaaac
    15961 tgactaaatc ataattatta tcatccataa caatcgtttc tataaaattt agttctttcc
    16021 tgatttcaga ataagtggag taatctgtat atgtcagcgg atgcttgaat atgtccgaga
    16081 aatttttggt cgaaccatac gtagaaaacg aatattcaat cgttctaatt ttccattcaa
    16141 cgttagtttt aacttgcctg agcaaattct ttttgtctgt taaataactc gattcgatcg
    16201 attcataggt attctggtaa atgaataaac taaatcctat gacaagtacg gctcctaata
    16261 aaaacatcgg taaaaatatt ttataaaata ctgtactttt cttcattttc ttcctctcct
    16321 ccttttaaaa taaaaggctt tcatttttct gtaaaattga tactcatcta attaaatgag
    16381 cattccccgc tttcaagaat agcataatta aaaataaaaa tccaagtaat ttttaacgtg
    16441 tgcaatcttt tcatatcaaa gatctattga cttatcgtag ttatcgtaat atgatgaatg
    16501 cgttaacaaa aagtgaaaaa gtaaggaaaa tgatggaatg gtaacgatca aagatatcgc
    16561 taaagcagct ggcgtttctc atacgacagt ttctcgtgct ttgaataaca gcagtttaat
    16621 aaaaaatgaa acaaaacaaa aaatacgaca actagctaag gaaatgaatt attcgccaaa
    16681 ctatagtgca aaaggtttag tgaatcaaaa aaaatatcta atcggactat ttttctcaag
    16741 tttgcataaa ggaacttcat caaatttcct agcagattcc attgcaggca tccattcagt
    16801 attagacaca aattacagtt tatctgttga aagtatcgat gttgttgatt taacagaaat
    16861 caacctgcaa cgctacgatg gactgatcgt tatgagtcaa agtgatgatg atcagccttt
    16921 catcgactat ctcaaagaaa aagaatttcc tttcgttgtt gtcaatcgtc acatcaatga
    16981 tccagcggtt atcaacgtca ctgccgatga tgcggccggt gttatgcagg cagtagatta
    17041 cggtattgga tgcggacata cgaagatcgc ttatattggc ggaaagaaaa attttcgttc
    17101 gacaaaagaa cgggaaaaag gggtattgaa aagtctaaaa aaagcgagca tccctgtcaa
    17161 tctagcctat tttttaacag gagattacag cttagaaagc ggcctccaaa acatggaata
    17221 cctattatca ctttctgacc tgcctactct ggttttttgc ggcaacgacg acatagcgat
    17281 tggtgcattg agagctgtac atttagctgg cctccgtgtt ccccagaaca tttctctgat
    17341 cgggttcgat gattctccag tcgtctccta tctcaatccg ccgcttacca ccgtacgtaa
    17401 gcctttgaaa gaaatgtgtc aagaaggaac aaagctttta ctagatttga tcgaaggcag
    17461 gacgatcgaa caatctaaaa ttgagctctc caccttgttg atccttcgtg agtcgatcaa
    17521 ttacttgtaa actacaagta attttatata aaaatgttaa cgtgtgcata acacagaaag
    17581 gaagtttata tgaaaaaact gacaaaagaa ttagtgaaaa aaaacgaagc acctgtaaaa
    17641 gttcttcagt ttggtgaagg caattttatg cgtggattta ttgattggca gattcagcag
    17701 ctgaataacc aacaattgtt taaaggtaat gttgcaatca ttcaaccttt agaacaaggt
    17761 cttggaaata tgatgaacca gcaagataat ttatatacgg tcattttaca aggactcagc
    17821 aatggcgaaa tcgttgatac ttccgagatt atcaccgtag tagaacaaat gatcaatcct
    17881 tatgatgaat gggatgctta tctatctcta gcagaaaatg acgacttggc ctatatcgtc
    17941 tccaatacaa cagaggcagg aatccaattc gtggagactg ataatttaac agatactccc
    18001 ccacagagct tcccgggcaa actgacagcc tttttatacc gacgtttcaa attaaacaaa
    18061 gctggcttta ccatcattcc ttgcgaactg attgacagaa acggcgaacg tctaaaagaa
    18121 atcattttac gctacgcaga aaaatgggat ttagaacctg cttttgttga gtggttagaa
    18181 aaagaaaatg ttttctgttg tagtttagtt gatcgcatcg tcccaggtta tcctcgcgaa
    18241 gatgcaggtg ttttcaatca acggcataac tatgaagatc aattgatggt caaagcagaa
    18301 ccattcatgc tttgggtgat cgaagggcct aaagaattgg agaatcaact accattcaaa
    18361 caggctggct tgaatgtcat catcacagat gatatgactc cttatcgtga acgtaaggtg
    18421 catttgctta atggaccgca tacagcgatg gtccctcttg ctttgttggc ggaattggaa
    18481 actgtagaag aagtaatgaa agatccttta ttctccgcat atgttgatca gttattcaat
    18541 ctagaattga ttcctatgct ttctttacct aaagatgaat tagccattta tgctgaccaa
    18601 atcaaagaac gtttcttgaa tccttttgcc catcacaaat tagaagcgat ttcattaaat
    18661 agtgtttcaa agttcagcac ccgtctgctt ccagtgttca agaagtatat cgaagaacaa
    18721 aatcaggtac caccgttaat cactgtttca ctagctgcgc tacttcttat gtatcgaggc
    18781 gatcaagtaa agccacatga tgatgaaaag acgataagcg aatttactga tgcttggtct
    18841 gataatggaa cagctattcc tcgattattg caaaacgctg cgctttgggg agaagatttg
    18901 tctcaaatac cgaatgtgac agatacagtt caagaaatag ctgcaaagat cgatcaaaaa
    18961 ggtgtccggt cagtattaca agaaatgaaa ggaacgatgg tccatgcttg aaaccctgca
    19021 accaacaatg aaattaaatc gacgagacag tgtggtcgtc gcattaaccc ctattccaaa
    19081 acaaacacaa ctgacgattg atcagcaaac gatcaccact cttgaagata tcccgcaagg
    19141 tcataagatt gcattgggtg atttgaaagc tggagacaac gtgatcaaat atggctatcc
    19201 aatcggtcat gtgacgacag acgtaactgc cggtcaatgg ctgcacactc ataatgtaaa
    19261 aaccaatctt tctggtgaat tggattatcg atatgaaaaa gatgtccatc caagtcatta
    19321 cctttttgag aaccgaacat ttcaaggtta cttgcgaaaa aatggaaaag tagggattcg
    19381 taatgatttg tttttagtac ctaccgttgg gtgtgtgaat ggcattgctg aactgatcgt
    19441 caaacagttc aaggaaaaac atccagatct gggacagttt gaccatatta cgattttaaa
    19501 gcatccttat ggctgttcgc agcttggaaa agatcatcaa aatactcgag aaattttagc
    19561 ggacgcagta aatcatccca atgccggagg agttttagta tttggattag gttgtgagaa
    19621 caatacagtt cctgaattca aaaaaatttt aggtgaatat gatgaagaac gagtgaaatt
    19681 tctagtggct caagatgttt acgatgagat cgaacaaggt gtggctctat tagaagagct
    19741 tttaacagcg gcggaaaatg accagcgcat atcagtcccg ctctctaagt tgaatgtcgg
    19801 tttgaaatgc ggcggttctg atggtctatc gggaataact gctaatcctt tacttggtgc
    19861 attttctgac tacttgattg ctcaaggagg cagcacgatc ttaacagaag tgccagaaat
    19921 gtttggcgca gaacaagtat tgatggcacg agcggaaaat gaagaagttt ttgactcaat
    19981 cgttgacttg atcaatgact tcaaacagta tttcttgtct tacggggaac cagtttacga
    20041 aaacccatct cctggtaata aagcaggtgg gatcactaca ttagaagata agtctttagg
    20101 ctgcacgcaa aaatcaggaa gctctcctgt cgttgatgtg ctacaatatg gcgaaaaaat
    20161 cagaaaacca gggcttagtt tattgcaagc tcccgggaat gatcttgtag ctgcctctgc
    20221 tcttgcttca tccgattgcc agttggtctt gtttaccaca ggaagaggga ctccgtttgg
    20281 ctcatatgtc ccaacggtca aggtatctac gaatacaact ctttttgaac gcaaaggtca
    20341 ttggatggat tttaatgcag gcgtcttatt agaacaacca atggaagtaa tcttagaatc
    20401 gtttgttcaa aaaatcatcg ctgtagctag tggagaagaa acgaaaaatg aacaaaatga
    20461 cgttcgagaa attgccattt ttaaaaacgg agtaacactt tgattttcat aaaacagtat
    20521 aaaaagaaag aaggaagatt tatgttttta tctgatgatt ttttattaaa agacgattgg
    20581 gcgaaaaagc tttaccattc ctacgcaaaa aacatgccca ttattgatta tcactgtcac
    20641 ttagatccaa aagaaattta cgaaaacaac aatttcagca atctgacaga agcttggtta
    20701 ggaggcgatc attacaaatg gcgcttgatg cgagcttgcg gcgtgcctga agaaaaaatc
    20761 acaggaaatg cttctgattt tgaaaaattt ttagcttggt gtcaaaccgt accaaaaatt
    20821 atcggaaatc cgctttacag ttggtcacat cttgaattga agcgtttctt cggtattgac
    20881 ttgttgataa atgaagaaaa tgcagagaaa atttggacac aagcaaatga aattttggca
    20941 gctcctgatt ttcgccgtcg ggaaatcgca aaaaaatcga atgtagaagt gatttgtaca
    21001 acagatgatc ccgcagacga cttgcactat catcagttgc ttgctcatga agaaccagat
    21061 ttgaaggttc taccttcatt ccgtccagat aaagcactca atattgaaaa agaaggattt
    21121 aatgcatggg tcacactact ggaagaagca gctgaccaaa cgatcaccac ctatcaagaa
    21181 ctgatagaag tcttagggca gcggatagaa tacttccatc aacatggatg tcgtgtttcc
    21241 gaccacgctt tagacatctt acgctataaa gaagcggatg aaacagtatt agaagagatt
    21301 tttcaaaaag cacgagctaa caaactatta tcttcagatg aaatcgatgc ttatcttaca
    21361 gaaacactga tacatttgac ccacttctat cattctcata attggacgat gcagctgcac
    21421 atccatgctt atcgtaactg taatacacaa atgttggaaa aattagggcc cgataccggc
    21481 tatgatggaa tgaatgatct ttctttgact attcctctgc aaaaattatt gaaccgtgca
    21541 gaagaaacgg atcagttgcc aaagacgatc ctttattcat tgaatccgaa tgactatcct
    21601 gcgattttag ctttgatggg ctgtttccaa aaagaacaga atggaaaact gcagttaggt
    21661 tctggatggt ggtacaacga tactcgagct ggtatgcgcg atcaattgac acaatttgct
    21721 gatggtagtg ctttggggaa ttttgtcggc atgctgacag attcaagaag tttcctgtcc
    21781 tacactagac atgaatattt ccgtcgtgtt ctttgtgaat ttttaggcga aatggtcatg
    21841 cgaggagaag cacctgaaga tgaacaactt ttaggaagtc tagttcaagc gattagttat
    21901 acaaatgcta aaaattactt tggctttttt gcctaattga ttaatagtaa cagtaacgaa
    21961 tcaaaaacag gatagtgaaa taacggaatc cgtttatcca cgttttagag aagaagacgg
    22021 accaaatt
//
LOCUS       DAFKHN010000046        21769 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFKHN010000046 DAFKHN010000000
VERSION     DAFKHN010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.046"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            60..614
                     /locus_tag="LY912_001733"
     CDS             60..614
                     /locus_tag="LY912_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBM6955416.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(787..1260)
                     /locus_tag="LY912_001734"
     CDS             complement(787..1260)
                     /locus_tag="LY912_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBM6955417.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1272..1808
                     /locus_tag="LY912_001735"
     CDS             1272..1808
                     /locus_tag="LY912_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBM6955418.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            1848..2219
                     /locus_tag="LY912_001736"
     CDS             1848..2219
                     /locus_tag="LY912_001736"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBM6955419.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2503..3774
                     /locus_tag="LY912_001737"
     CDS             2503..3774
                     /locus_tag="LY912_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBM6955420.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4019..5044
                     /locus_tag="LY912_001738"
     CDS             4019..5044
                     /locus_tag="LY912_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6955421.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5338..6447
                     /locus_tag="LY912_001739"
     CDS             5338..6447
                     /locus_tag="LY912_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBM6955422.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6530..7426
                     /locus_tag="LY912_001740"
                     /pseudo
     CDS             6530..7426
                     /locus_tag="LY912_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7442..8266
                     /locus_tag="LY912_001741"
     CDS             7442..8266
                     /locus_tag="LY912_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6955423.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8298..9608
                     /locus_tag="LY912_001742"
     CDS             8298..9608
                     /locus_tag="LY912_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBM6955424.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            9756..11015
                     /locus_tag="LY912_001743"
     CDS             9756..11015
                     /locus_tag="LY912_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBM6955425.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11025..11897
                     /locus_tag="LY912_001744"
     CDS             11025..11897
                     /locus_tag="LY912_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6955426.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            11909..12739
                     /locus_tag="LY912_001745"
     CDS             11909..12739
                     /locus_tag="LY912_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6955427.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            12779..14962
                     /locus_tag="LY912_001746"
     CDS             12779..14962
                     /locus_tag="LY912_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBM6955428.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15023..16243
                     /locus_tag="LY912_001747"
     CDS             15023..16243
                     /locus_tag="LY912_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBM6955429.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16240..17700
                     /gene="gtfA"
                     /locus_tag="LY912_001748"
     CDS             16240..17700
                     /gene="gtfA"
                     /locus_tag="LY912_001748"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBM6955430.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            17777..18883
                     /locus_tag="LY912_001749"
                     /pseudo
     CDS             17777..18883
                     /locus_tag="LY912_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19205..19414
                     /locus_tag="LY912_001750"
     CDS             19205..19414
                     /locus_tag="LY912_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBM6955431.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19407..19556
                     /locus_tag="LY912_001751"
     CDS             19407..19556
                     /locus_tag="LY912_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBM6955432.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            19710..20375
                     /locus_tag="LY912_001752"
     CDS             19710..20375
                     /locus_tag="LY912_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBM6955433.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20659..21744)
                     /gene="xerS"
                     /locus_tag="LY912_001753"
     CDS             complement(20659..21744)
                     /gene="xerS"
                     /locus_tag="LY912_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBM6955434.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         7394 a         3285 c         4194 g         6896 t
ORIGIN      
        1 ttatggtaaa atatatacat aatcattaac tcagaatatt tttaagaagg gaaacaatag
       61 tgagctataa tgtacaaccg ttaaggacaa atgaagagat acaagatttt cagttttggc
      121 taagaagaac aagtaatccg gaaagagata gttttttatt tttgtttgga atcaataatg
      181 ggttacgtat gtcagatatt ataggattaa aagttggaga tatacgaggc aaaagtaagc
      241 ctattattgt tgaacataaa acaggtaagc gaaaaccgat ttttatagat aatttgagag
      301 aagaaatttt attatatact gaaggtaaag aagaaaatga ttggttattt ccgagtcggc
      361 aacaaggtcg acatataaca agggatcgtg tctatcagat atatgcagat atagcagaaa
      421 aattaggacg agatgatata ggaacacata cattaagaaa aacttttggg tatcactact
      481 acaagaaaac tagagacatt gctaccttaa tgtttatttt taatcatagc tcgcaagcaa
      541 ttacaaaaag gtacattggt ataactgaag atgaaatagg agcatcactt cgtggattta
      601 aactaggtgt ataatttaaa aatttttata aacagtaaag acaaagatta aaagctattt
      661 ttatctagaa cgattttatt tcataaagtt cgcggaataa aagctggggt tactggtact
      721 tggtataggt tcgtgttata taaactaagt aattaaataa catttttagg ttggaaaagg
      781 atgaaattaa aaaaagagaa tcaatacggt ctcaaaaacg caaacgctgc ggaataagaa
      841 aaatactgat aactcaacgt ttagcagact atctaatagg gatagtctgc ttttttcgtt
      901 tttgaccata cttttgacct tctgcaaact tccttgcttt tcctctgtag aactcatgaa
      961 atctgcaaaa cgaattgccg tttcctctgt ctgctttttc gcgatatggg tgtatatatc
     1021 atccatagtg gttttaatat ctgtatgtcc aagtcgaaca tacacttctt tgacagacgc
     1081 accagattca aagagcagac tacaatgggt atgacgaaaa ccatgaagtg tgatatgttt
     1141 taagttattc tctttaatga tgattttcaa attgtgattt acatagtcta aataaagggg
     1201 cttattttct tctgatgaaa acaaaagttg ttcaccatct tttataggtt tgattctcat
     1261 ttttagatat tatgcccgca cgtattcatc acatttctat tgtgaatcgc tttattcgac
     1321 cgacatttga cttttatcat aatatactcg gtttaaaatt actaatgaaa acaattaatc
     1381 aagacgatca taccatgtat cacctgtttt tttcagataa tcaccaccgt gtgggaactg
     1441 aactgacttt ttttgaagta caagaaggga acaaccagtt ttttggaacc aatacgattg
     1501 aacgaacgat actaaaagtt ccttccgaag catcattgca tttttgggaa atatattttg
     1561 aaacacaagg cgtttgccat tatggaatcg aatcattttc tggacgacct atcttacgtt
     1621 ttgaagggcc agatgcaaca cgattagctt tagttccctt acgcgaattt gaagatattg
     1681 atgattattt cccgtatgtc acagaccaga tccctacaga gcatgccatt ttaggaattg
     1741 atgccattca actacgcgta caatattccg atgcgactga acgagagtta ttgtcggtag
     1801 gctggtagca caaagaatac gtcagtttct tttcgggtca tcaacgagtg acaatcttag
     1861 aaaatcaaga cactcagttc tatcaagaag ttcagattat tcaagatcgt gagaatccag
     1921 ttgccattga agggattggt agcgtccatc atgttgcgtt tggcgtagaa aataaatctg
     1981 atttacaacg catcgacaaa caattacaag agcgcaattt tataaattca ggaataaaag
     2041 atcgtgaatt ttttgtatca ctttattatc gtgacccaaa tcaattattg attgaaattg
     2101 ctacagggga aggaaaccta gatgcaaaag cgtatgaaaa tcaaagtcca cgctttgaag
     2161 aaattccttt atttttaccg cagtacttaa atttcattcg tgaacaagtg gagcaataat
     2221 tagctaatca aatccatgac gaagagtaag aggttgactc ataagtcaaa aaataaagaa
     2281 aaacgcatca aatccattct aaagaatgtt gatttgatgc ggttcctatt tttataaact
     2341 atcattttcg actaataaaa ctacttatga gtcagcctct ctttttttct tgatttttat
     2401 acctctttct aggtaaacta aacatctgcc aaaaataccg tgtctcattg aaacattctc
     2461 aactatttca aaataaaggg gagtaccaaa tgaacgagta tattgaaatt atccacgcaa
     2521 gagaaacaac ttaaaaatgt cagtctcaaa attcccaaaa ataaaattag tatttttacc
     2581 agcgtatctg gttcaggaaa atcatcgatt gtttttgata ctattaccca agaagctggt
     2641 cgtcaactga atgacaccta tgatagtttt acccgtttat ttttacctaa atacagtcgt
     2701 ccagaggttg atgagattga taatctttct acggcgattg tggtcaatca aaagaagatt
     2761 ggtggcagtg cgcgctcaac gttagggacg attactaaca tcaatgcgtt atttcgtgtg
     2821 ttgttttcat gttttgcaac acctagttta ggatatgcaa atgcttattc atttaatgat
     2881 cctagtggaa tgtgttctgt ctgtcaggga atcggtaaga cgattgcatt tttaatagga
     2941 ttgctttatt tttcggctat tgataatgct gattttgtat tttctgatcc atttaccgca
     3001 gaagttttgt ctggaattga ggaacaggca aagaatcatg gttattttgt attggtgcat
     3061 aatgttaatt cagcagaaga tgttaaaact attcagagaa attggcgttt tgaggggttc
     3121 attgttgttg gtgtacgtgt aaaagaattt ttggaattaa ataacgtttt tgatggtcct
     3181 gttgtttata ttgatacgca tctttcaaaa gagacattaa gagaacttga acaacaaatg
     3241 aatcgtttat ttgtaaatac aaatgattac caagctagta cattggcagt ggaacatttg
     3301 attcattatg gtcatgagaa aatagcgttt ctttcttttg actacattgt aggtgaacca
     3361 agtgttattc aagaacgaca tcaagcttat atcgatacat taaagaaata tcatttaacc
     3421 tttaaatcgc attggatata taacaactct gaatttgagc gaatttatca agaattagct
     3481 gaatttactg caattgttgt tactggagat tatttagcgg ctaaattagt aaaattttta
     3541 aaaaataaga ataaacgagt gatggaacaa ttatcgatta ttggatttga tgatattact
     3601 tttgcagaat taatggatcc tgcgttgaca acaatacgac taaatccagg taacaagggg
     3661 gcgattgctt ttcaccaact gattggactg gccaaacaag aagaaataaa aaatcaagta
     3721 ctactattag agggagaatt gatttctcga gactctgttc acaaaatcaa ataaaaaagc
     3781 tctgtgaaat aagtatagtt aacaataaaa tatccgaacg atagagagaa tgaactgtga
     3841 tctagcagtt cctcgtcgca aattcactag aattagcatt atttactcta aattgttcgg
     3901 atattttttc ttgtttttaa ttatgattac agtgcctatt tttaacgaaa tttgcttatt
     3961 ttcaaaatgt atgattatat gttagtaaac actttcaaat atgaaaagag gagctattat
     4021 ggtaggaatt agggatgttg caaaacgggc gggtgtgtcc attgcaacag tatcgcgcgt
     4081 gctaaatgag gatccgacac tttcagtaac cgatgaaacc aaacgaaaga ttgcagaatc
     4141 ggttaatttt tatcattatg tcaaaaaaag tcccgttgca aaaaatttaa caaatattgc
     4201 attaataacg acagtttctg aagtagatga gttggaagat ccctattttc gaacgattcg
     4261 cagagggatt caagtcgaag cagaacaaag caaagtcaat ttgaagaaaa ttattcgttt
     4321 gtcagaaaca ccgttggagc aagacgattt gctaaaatgt caaggtgtgt tgattattgg
     4381 gcaggtgcta tcttctgtga ttgaagaagt atcagcaatt aattcgaatg tcgtagtgat
     4441 tgatgaccct agtattgaag ctgaagtaga tgcagtttat actgatttaa caaaagcaac
     4501 gaatcagcat ttagatcgat tgtataaaaa aggacaccga aacattgcgt ttatcggagg
     4561 aggacgtgtt cgtttagata gccaaggaaa taaacacgtg tcagatgatg attatcgaaa
     4621 aatagcctat gagacgtgga tgaaacaaaa aggattagaa aaatatagtc aaatttattt
     4681 agaaggctgg accacacttg acggaatgca ggcagcagat ttacttttga aaaaacatgc
     4741 taaagataag ttgccgactg ctatcatggt aggaaatgat cctattgctg tgggggttta
     4801 tcgttcactt caaaaaaatg gtctacatat tccagaagat atttcgattg tgagttttga
     4861 taatattgaa gttgctgaat ttttaacacc tgcattaaat acggtgaatg tgaatacaga
     4921 agaaattgga aaactagcag ttcgcatggt taatgaacga ataaaagaag ttagaaatgt
     4981 ttcgatcaaa gtgattgttt ctaataatat tattgttaga gaaagtgaaa aaaatatcga
     5041 ttaaaaaagt aaacatccaa aaaagggtgt ttactttttt gtttactaat atttttagta
     5101 aaaaatctcg acaaaacatt aagtaaacag ttatggtgtt gttaacaaaa agaaaacgca
     5161 ttcaaaacag gaggaattaa gatgaaacat ttcaaaaaaa tagctttaac agggatagct
     5221 gttttaactg ggacattact cgcagcatgt ggtgggggag atagtaattc taaagacggg
     5281 caagtaactt taagctatgc gagttgagat actgaccaag ctccaggact aagaaaaatg
     5341 ttagatgaat ttgaaaaaca aaatcctgat atcaaagtag aaatggagac aacgccttgg
     5401 gatcaatatt gggttaaatt agaagctgca acaacgggag gtaatatgcc agatgtagta
     5461 accatgcact ctagcgaatc ctataaatat atgtcacaga atgctttgat gggacttgat
     5521 gatgttatca aagaaaatga tattgacatg ggaaacttta ctgaaggaat tgctgatttc
     5581 tatacgcttg aagacgaact atacgcaatc cctaaagatg cttctgtagt ggggctatgg
     5641 tacaacaaag aattatttga taatgcaggt gtcgattatc cagatgaaac atggacatgg
     5701 gaaacactca gacaagctgc aattgattta acagatgaat caaaaggcat ctatggtttt
     5761 gcatcacata ttggaacaga gactggctac tggccattta tttatcaaaa tgggggagaa
     5821 gtatttgccg atgacaatac aaaatcaggt ttgaataccc cagaagcaca agaagcttta
     5881 gctttttatc gagatattgc acttgttgat catgcttcac caacaattac agaattacaa
     5941 gatcctgata agttaagtcg ttttcaatca ggtagattag caatgatgat tgaaggaaac
     6001 tggtttgcac cgggattttt gaaaaatgac tatctagttg aaaatgttgc ttctgccgtg
     6061 ttacctaagg gaaaagttaa tgcaacaatt acaaatggac ttggttgggc tgccagtgcg
     6121 agtacaaaat acccagaaga agtgaaaaaa ctaatggcat ttttagctag tgaggacgcc
     6181 aataaaatcc aagcggaaac gggggcatca atcccagcac taaaaggctt tgaagacgag
     6241 tgggctgctt cttcagatac aattgatttg agtgcttttg gaaaaatgtt ggagtatgga
     6301 gtccctcgtc catacaataa agatggatta cgagctgaac aagcagaagt tcaaattatt
     6361 aaccgtattc tgtctggtga agtaactgtt gaagatggaa ccgctcaaat tgaaaaagaa
     6421 gtcaatgcga tattgagcgg aaattaaatt agttaattat acaatataca ggcgaaagga
     6481 ttctatttcg tctgtatatt aatggatgaa taccaaaaag ggggatatta tgaaaaatcg
     6541 aatttttgga aaatatcgta aagatcaagt gatatggggc tatattttta tttttccaac
     6601 ggcattagga ttaattttat taaatatatg gccagcaatt caaacagcaa ttttaagttt
     6661 tcaaaaaacg gtagggttcg gtgatactga atgggtcgga ttaagaaatt accaaaaaat
     6721 gtttgcagac ggtgaagttt ttcagtcttt attaaacaca ttaatttatg cagtggtttc
     6781 gatacctagt attgttgtat tatccttgtt ggtggcagtt ttaatgaata gaaaagttaa
     6841 aggattgtcg atttatcgga caatttattt tctaccagtc gttgctgcac catccgcagt
     6901 cgcaatgatt tggcgctgga tgttcaataa tgattatgga ctgattaata acatgttggc
     6961 taaaataggt ctcgatggac cagcatggtt aacggatcca tcgattgcga tttattctat
     7021 tatcattgta ggagtttgga gtgctattgg ttataacatg gtgttattac tagccggctt
     7081 ataagaaatt cctaaagatt attatgaagc agcggaaatt gatggtgcta gtccaatcca
     7141 gcagtttttc aacattacgt taccattagt tacaccaaca ttattttttg tagttgtaac
     7201 aacagttatc aatgctttcc aagtatttga tgttattttt atgatgatta ctcctaatag
     7261 taccgccatg tttaaatcac aatcattagc ctatttattc tataaacatt catttatttt
     7321 aaatgacaag ggatatggtt cggcaatcgt tatgttcctt ttagtgatta tattaattat
     7381 tactgcaatt caaatgaagt tgcagaaaaa gtgggtaaac tattaaggag gctatcaaat
     7441 tatgaaaaat aaattttttt caaatgcgcc aatccatatc atgcttattt taggtggtat
     7501 tgcaatggca ttacctttta tttggatgat tttaacttca gggaaaacgt tggttgaatc
     7561 tacccaaatt ccacctacaa ttttccctga gaaatttcag ctaagtaact atcaacaagt
     7621 acttgattta ttaccattca tggcttttta tatcaataca tttttaatgg ttgttggacg
     7681 agtgattggc tcggttttat tttcagcaat ggctgcatat gcttgtgcgc gtctaagttt
     7741 tccagggaaa aatatccttt tcagcttagt acttattcaa atgatgattc ccggttccat
     7801 ttttattact ccacagtatt tattagcaca aaaattgggt attttaaata caattccagc
     7861 attaatatta ccaggggtag ttagtgcgtt tggtacgttt ttattaagac aatttttctt
     7921 aggtttacct gatgaattgg aggaagcggc ctatttagaa ggtgccaata tttggacgat
     7981 ctttttcaaa attatgttgc cgcttgctaa atcaggattg gttgcacttg gaatattcac
     8041 agcgttgttt gcatttaaag atttaatgtg gccattgatt gtcaatactt caattgataa
     8101 gatgccttta gctccgggat tagcaaactt acaaggacaa tatgccacga acttcccaca
     8161 attaatggca ggttcgttat tagcaatttg gccaatagtt gtgatattca tcgttttcca
     8221 aagaaaattc attgaaggaa ttgctacaac aggtagtaaa ttataaaact attaattagt
     8281 gattggagag taagtacatg acaaaaatta catttattgg tgcaggaagt actatttttg
     8341 caaaaaacgt attaggcgat gcgatgttaa ctccaagtct acaagatgca catattgcat
     8401 tgtacgatat tgatgaaaaa cgactaaaag aatcaaattt aatgcttaaa aatattaata
     8461 aaaattcgaa tgaaaatcgt gctgatattg tttcttatta tgatcgcaaa gaagcgttaa
     8521 gagaggctga ttttgttatc aatgctattc aagtgggtgg ttataaacct tcaacagtga
     8581 ttgattttga tattcctaaa aaatatgggt tgcgacaaac tattggtgac accatgggga
     8641 ttggtgggat ttttagaacc ctacggacac taccagtaat gttagacttt gctaaagaaa
     8701 tggaagaagt ttgtccaaat gcttggttat tgaactatac aaatccgatg gcgatgttaa
     8761 ccatgggtgt tttaaaagcg acgagtatta agactgttgg tttatgtcat agcgttcaag
     8821 tatgcgtacc agaattgttt gagcatttag gaatagccga tcaatatgac ttaaatgact
     8881 ttcaatggaa aattgcaggc attaatcata tggcattctt gttggaaatt acaaaaaatg
     8941 gggaagattt ctatccaaca attcgtcagt tagctgcaga aaaaccaaat ccacatccag
     9001 attctgtacg ttttgaattg ttgaaacgtt ttggttacta tattacagaa tcaagtgaac
     9061 acaatgcaga ataccatcca tactttatta aatcaaaata cccagaattg attgacgaat
     9121 tagggattcc gttggatgaa tacttacgtc gttgtgaaca acaaattaat gattgggaaa
     9181 gcatgcgaga ggacattgta aataatgggg agttaacaca tacgagaagc cgtgaatatg
     9241 cttcatatat catggattct attacgacag gaactccgtc agtgattgca ggaaatgtct
     9301 taaataaagg cttaatcaca aacttaccga cagatgtttg tgtggaagta ccttgtttag
     9361 tcgataaaaa tggcgtgcaa ccaacctatg tcggtgaatt gccaacacaa ttagctgctt
     9421 taaatcggac gaatatcaat gttcaagaac tgacagtaga agccgcttta acactagata
     9481 aatcaaaaat ttatcaagca gcgtatttag atccacatct atcatctgaa ttgtctttaa
     9541 cagatatcaa aaatttagtg gatgatttaa tcgaagcaca tggggactat ttacctgaat
     9601 ataattaaaa agaagctgaa agagtaagga attttcaatt ccttactctt ttcttagtta
     9661 aatttagtaa aaatattgac aaaacactta gtaaacagtt acattagtgt taacaaaaag
     9721 aaaacgcatt caaattgtat aaggaggagc ataaaatgaa gtggtctaaa aaaattattt
     9781 tagcttgtat agcactagga gcaacgatct ctttgactgc ttgtggaaaa aatcaggaag
     9841 atgcaagcgg taaggtagaa atagagtttt ttaatcaaaa aaaagaaatg actcaaacga
     9901 ttcaggagat tgctaaagat tttgaagcaa aaaaccctga tattcatgta aaagttgtgg
     9961 atgtaccgaa tgctggtgaa gtaattaaaa cacgtatgct tgcaggcgat gtaccagatg
    10021 tcattaatct ttatcctcaa agtatagaat tgaaagaatg ggcgaaagct ggttatttag
    10081 aggacttaac cgaagaaccg tatttagaga atatcaaaaa tggatatgca caacgttttg
    10141 ctattgagga tcgtgtatat agcataccat taaccgctaa tgtctatggt ttttactata
    10201 acaaaactgc ttttgaggaa atggggattc aagcaccaga aacttgggca gaatttgaaa
    10261 aaatagtagc tgagattaaa gatcaaaaca aagtaccgtt tgcgattgca ggagcagaag
    10321 gctggacttt aaatggttat caccaactag ctatagcgac tgctgctggt ggtgaagagg
    10381 aagcgaacaa tgtttggcgt ttctcagaag ttaatggaat taatgctgaa agcaaagaaa
    10441 tgcaaaaaga ttttaatcga ttagatttgt taagagaacc aaaagctttg caaaacaact
    10501 ggcaaggtgc cggttataac gatacagtag ttacttttac aaaaggtgat gcgttgatta
    10561 tgccgaatgg ttcatgggca atgccgatga ttcattcaca aaatccagat tttgaagtag
    10621 gaacttttcc ttttccagca gatgaagcag gtcaaagtct aacgattggc gcaggagacc
    10681 tagccttatc agtttctgca acttctcaac ataaagaaga agccaaacgt tttgtagaat
    10741 atatgacaac acctgaagcg atgcagaaat attatgatgt agatggtgca ccgtgtgctg
    10801 ttgagggcgt tatcgagaat actcaggatt caccattaag tggtttaact gaacttgctt
    10861 ttactgatcg tcatttagtt tggttagcca aagattggaa tagtgaaaat gatttttata
    10921 ccttaacaac aaattattta cacaatggca atcaaaaagc catgattaac gcattaaatg
    10981 ctttctttaa tccaatgaaa gctgacggaa ggtaggaaaa taaaatgaaa ataaaagaaa
    11041 ttttaaatcg ttactgggca atcatttttg tagcaattcc aattattttg cagatgattt
    11101 ttttctactt tccaatggtt caaggtgctt tttacagttt aactaattgg actggtctga
    11161 cttataattt tgattttgtg ggtttgaaca attataagat tcttttttct gatccgaagt
    11221 ttatcaaatc gattggcttc actttaattg tgacgctttg catgattgct ggacaaattg
    11281 gttttggtat tttgattgcg cgggcgttga acgcaaatat taaagggaaa acattcttta
    11341 gagcatggtt cttttttcca gcggtcttat cgggcgtggt tgtttcttta gtatttaaac
    11401 aaatttttaa ctatggttta ccaaaaattg gtagtatgtt aggcattgaa tttttacaaa
    11461 ccagtctttt aggaacaaca tggggagcga tttttgcagt aatttttgtt ttactttggc
    11521 aaggaattgc catgccagtc atcattttct tagcgggttt tcaaagtatt ccacaagaaa
    11581 ttattgaagc tgctagaatg gatggggcga atgataagca aattttttgg aatattgaaa
    11641 tcacctactt attaccaagt atttcaatgg tatttattat ggcattaaaa ggtggcttaa
    11701 cagcatttga tcaaattttt gctttaactg gtggtggacc aagcgatgcc acaacatctt
    11761 tggggttact tgtttataat tatgctttta aaaacaatca gtttggttat gcgaatgcta
    11821 ttgctttagt cttatttatc ttaattggga ttgtttcact ggcacaatta aaattatcga
    11881 aaaaatttga aatctaggag gtttcccaat gaaaacatca aaagaaaaaa atatttctaa
    11941 atacttgctt ttattattag ggggcttcat gattttagtt cccttagttt caacgctatt
    12001 cggttcattt aaaacaacac ccgatattat gaataatttc tttcgttttc ctaatccagc
    12061 gactttggaa aatttccgaa gattgttagc ggatggaatt ggtcattact tttggaattc
    12121 ggcaatcatc acaatcattg cagtagttgc tgtgacagca attattccta tggctgctta
    12181 ttcactagca agaaaaatga ctcgtgggaa agcatacgga ttgatgtatt tatttttaat
    12241 tttaggaatt tttgttcctt tccaagtaat tatgattccg attaccgtta tgatgagtaa
    12301 aattggttta gcaaatatgt ggggattaat cttactctat ctcacttatg ccgtaccaca
    12361 gacactattt ttatatgttg gttttattaa actaaatgtg cctatcagtc tggatgaggc
    12421 tgctgaaatt gatggggcta gtcactttac aacttatttc aaaattgttt tcccaatgtt
    12481 aaaaccaatg catgcgacga ctattattct taatgctcta tggttttgga atgatttcat
    12541 gctaccatta ttaattttaa atcgtgattc taatatgtgg acactaccat tgtttcaata
    12601 taattatacg ggacaatatt ttaacgacta tggtccaagt tttgcttcct atacagtagg
    12661 aattgtcacg attacactag tttatcttgc tttccaaaga agtattatag ctggaatgag
    12721 caatggagca gtgaaataac caataaatta ttctcattat aaaggagttc ataaacttat
    12781 gattatattt gacaatcaca cacaaacatt tcatttacaa aataaaaaaa ttagctatct
    12841 attaggaatc gaagaaaata attatttaac gcatctttat tttggaaaaa agattacgca
    12901 ctattctggt gggtatcgct acccccgaac agatcgttcc ttctcaccca acaatgcaaa
    12961 tgcgcaagat cgtttattat ctttagacac attaccatta gaatttccag gatatggaca
    13021 tggtgatttt agagaaccgg cgcataatat taaattagga aacggtagtc gtgtaaatga
    13081 ttttcgttat gatagctacg aaattcaaaa aggaaagccc agcttagcgg gattgccagc
    13141 cttatatacg gaagatgatg atgaagctga aacgctgatt attcaattga aagacgcgat
    13201 tagtggattg actttacagt tgttctacac aatttatcaa aatcacagtg taattattcg
    13261 ttctacgcaa ttagtaaata atagtgatga aacagtggag attaaccgct tagctagtca
    13321 atcaattgat tttccaaatc gtccactcga gttaattcat ttaaatggta cctgggcaag
    13381 agaacgtcaa atgactagag aaaaaattca tacagggata aaagtattag atagtaaacg
    13441 cggatcaagc agccatcaac aaaatccgtt tgttgcttta gtagatgcca aaacagatga
    13501 atttcaagga gaggcatatg gatttaattt agtttatagc ggtaatcacg aaacggtgat
    13561 tcaaaaagat ccatttgacc aaacacgggt cattatggga attaattcat ttaattttgg
    13621 ttggcaacta aaaactggcg actcatttca aacgccagaa gtcgtgatgg tttatagtaa
    13681 tgaaggtctg aatacgttat cacagacgta tcatgaattg tataatcacc gtttaattcg
    13741 tggaaactat cgtttaaaag aacgtcccac gttaatcaac aactgggaag caacgtattt
    13801 tgattttaac gaagaaaaaa tcatgaatat tgtcgatgat gcgaagaact tgggcattga
    13861 aatgtttgtt ttagatgatg gttggtttgg cggtcgtgaa aatgacttca cttcattagg
    13921 tgattgggtt gaaacagaag gcaaacttgc ttgtggtttg gaaaatttag ccaagcaagt
    13981 gcatgataac gggatgaaat ttgggatttg gtttgaaccg gaaatgattt ctgaagatag
    14041 tgaactattt cgagcacatc cagattgggc attgggtatt ccaggtcgtg accgctcaat
    14101 tagtcgaaat caatatgttc ttgatttttc aagacaagat gttcgtgata atatctatca
    14161 acaaatgacg gcgatttttg atcgtgtacc gattgattat gtgaagtggg atatgaatcg
    14221 aaatatgaca gaagtctatt ctgtcttgtt ggactcaacg atgcaaggtg aagtggctca
    14281 tcgttatatg ttagggttat atgaattttt agaaaagtta acaacgaatt atccaactat
    14341 tttatttgaa agttgttcgg gtggaggcgg tcgttttgat gcaggtttct tgtattacat
    14401 gccacaaact tggacgagcg acaataccga tgccgtggct cgtctgaaaa ttcaatatgg
    14461 aaccagctta gtgtatccaa tttcaagtat gggtgcgcat gtttcagcag tcccaaatca
    14521 tcaaacagga agagaaacga gtttaactat tcgtggcaat gctgcgatgg ctggtgtttt
    14581 tggttatgag ctagatctaa cgcaattaac ttctgaagaa aaagcagaaa ttaaagaaca
    14641 agttgccttt tataaaaagc atcgccaact tttgcaatat ggaacttttt atcgcttgga
    14701 aagtccgttt gaaggcaatg atactgcatg gatgtttgtc tcaaaagacc aaacagaagc
    14761 catggtcttt tatttccgag tattagcaga agctgcgcat ccattagtca cattgaaatt
    14821 agcaggatta gcagaagaag caacttatca aatggaagat gtaacatttg ctggcgatga
    14881 attgatgaat ctcggttttt atattgactc agaactacat ggtgattatg cgacacaacg
    14941 cttttatttg aaacagatat agtagcttga atttacaata taagtgcaac accaaaagag
    15001 actcattcca aacgaagaaa atatgtttta tttacacgca tttactaaaa agcagcctga
    15061 tttgaattgg gaaaatgaag aagtacgtga agaaatctat gcaatgatta actattggtt
    15121 agataaagga ctaggcggat ttagaatcga tgcgatatta aacatcaaaa aaaaactaga
    15181 gtatggcatc tttgaatctg atggagaaga tgggttagcc ttcattgggc cctggattct
    15241 taatcagtcg ggcattgaag tgtggttaaa agaaatgaga gagcggacat ttaaaccaca
    15301 taatagtatg acggtagcag aagccgatgt tcctaatgaa cgtttagatg aatatattgg
    15361 tgaagatggc tattattcga tggtttttga ttttagttat acggatattg atgtacctga
    15421 aactggtgaa tggtttaaag atagccaatg gacatggacg gatatgcgta ccaatatttt
    15481 tacgaatcaa ttagttacgc aagataaagg ttggggcgcc ttatatttag aaaaccacga
    15541 tcaaccacgt tcaattaata aatatattcc agaagaatgg atcaatgatt atagtaaaaa
    15601 aatgttggcg acgcttttta tgttactaag aggtacccct tttatttatc aaggacaaga
    15661 actaggaatg accaacatag aaatggcatc attagaagat tttgatgatg tagctacgca
    15721 ttctcagtat aaacgggcat tagaatatgg attggcacca gagcaagcat tgaaagctgt
    15781 caataaacga agtcgggata attctcgcac acctatgcaa tggaatacgc aaaaaaatgc
    15841 cagattctca acttctgata atgtatggtt aaaagtaaat cctaattatc cagaactcaa
    15901 tgcagaagct cagttaacca atcaacagtc ggtattcaat tattatcatc aattaattaa
    15961 attaagaaaa aatagtgtat acaaagacgt gctaatctac ggacaatttc taccagtgaa
    16021 agataaaaat gaacatattt tgctttatga acgccaatta gaagataaaa tcgtattagt
    16081 tatcttaaac gttacagcaa cagaacaaga atattatgta gatgaacagt accaacaagt
    16141 attaatcaat aattatgaag atgttttatt agatcaaagt cgaaaattgc gtttacgacc
    16201 gtttgaaagt attgtattag ctaattatgg aggacaatta tgaaaattaa aaacgaagca
    16261 atgctcatca cctatgcaga tagtttagga aaaaacatgg gcgaattaaa acaagtctta
    16321 gacaaacatt tacaaggtgt tattggtggt gtacatctgt tgcctttttt tccatcgaca
    16381 ggtgatcgag gctttgcgcc gagtgattat acgacagttg atccagctct tggaacatgg
    16441 gaagatgtgg aagcattagg tgaagattat tatttgatgt ttgattttat gattaatcac
    16501 atttctcgtg aatcaaaatt tttccaagat ttcaaaaaaa accatgagca gtcaccatac
    16561 aaagaaatgt ttatccgtat tcatgaattt ttcccagaaa atcgaccaac acaagaagat
    16621 attgatttaa tctacaagcg taaagacaaa gcgccgtttc aaacggtaga atttgcggat
    16681 ggtacgacag aagaggtttg gaataccttt ggggaagaac aaattgattt agatgtgacc
    16741 aaagaagttg tgaaagaatt tattcgagaa accatcaaag atatggcgaa ccatggctgt
    16801 tctttaattc gattagatgc gtttgcttat gcgattaaaa aattagatac caatgatttc
    16861 ttcgtggaac cagatatttg ggaactttta gacgaagtgc gtcaagaagc agcgaaatat
    16921 gacgtcgaat tattaccaga aatccatgag cattattcca ttcaaatgaa aattgccaat
    16981 catgattatt atatctatga cttcgccttg ccaatggtca ctctgtattc actttatagt
    17041 ggaaaatcag aacgtttagc caattggttg aaaatgagtc cgatgaagca gtttacaaca
    17101 ttggatacgc atgatggaat tggtgttgtg gacgctcgtg atttattaac agatgaagaa
    17161 ttggattaca cctctgagga attgtataaa gtcggggcga atgtgaagaa ggtctattca
    17221 agtgccaatt acaataattt agatatttat caaattaaca gcacctatta tagtgcatta
    17281 ggcgataatg accgtagcta tctgttagca cgtgcgattc aagtatttgc gccagggatt
    17341 ccacaaattt attacgttgg gttattagca ggaaaaaatg atattgaact gttggaagca
    17401 acgaaagaag ggcgtaatat taatcgtcat tactatgatt tagccgaaat tgaagaagaa
    17461 gtgcaacggc cagtgattca acaattattt gcacttttaa aatttagaaa tgaatctgcg
    17521 gcgtttgatt tggatggaac gattgaagta gcaacgccat cagaatcaga aatagtgatt
    17581 acacgtaaaa ataaaaacgg tagtgatagt gcaacattaa cggctaactt ggatacgaaa
    17641 gaatttatca ttgagtctaa agatataaaa attttcacta gtgttgcatt aaaattttaa
    17701 cctattccat agaacaaaaa atcctttata ctagcacttg gatgacttat ccaagaccaa
    17761 taaaaaggac tcatacatgg ataagtataa aacaaataca gcatttaata aatggttttc
    17821 tgccataaaa ttaggaaaac tttctgtcaa ctcccaaaaa tgtatttttg attacaattc
    17881 gtatcgtaaa aaactgtctt ttgaagctgt gctcaagctc tttctctacg cagttaatga
    17941 agaaaaagaa agtttgcgtg atttgagtac agctcttatc gaccgatcgc tccaactaga
    18001 aaccgatgtg tcatcgatta gtcataccca attgtctcga gcatttaatg cacttgaacc
    18061 taaagtgtta gaagaaattt ttcaacaact gttagaaaaa gttcaacatc aaatcaaacc
    18121 aaccaagcga aatcatctgt atctgattga ttccagtacg ttttcgctta gtttaaaacg
    18181 tcataagtgg gcgactttcc gtcaaacaaa atcaggtgtc aagttacact taaactattg
    18241 ttatatggac gatactacga tgtatccaac tgattttacc ttaacaaatg cccatgaaca
    18301 tgatctcaat caactaccag tattggtgaa tcaaccagag gcaacttacg tgtttgatcg
    18361 tgggtattag gactttgaaa agatggatca gatgcattgg gatggctatt tcttcgtcac
    18421 tcggattaaa aaaaacacca aagttcacgt gatagatact ctggaaacat cgccagaaac
    18481 agaaattcta cgagacgagc tggttcgttt aggatctaaa acctatctaa ccgccaattt
    18541 ccgactagtc actgttcaag ataagaacgg acgtgtgttt caatttatca ccaatcgaat
    18601 ggacgtctct tcaaaagaaa tctctgatat gtatcacgct cgttggcaaa tcgaattgtt
    18661 tttcaagcac atcaaacaac acatgaccat taaaaccttc ttttctcaaa gtgaaaaagg
    18721 cgtgcagaat caattgattt taacgatgat ttccgctctc ctcacgtttc tcatcaaatt
    18781 ggagacgaaa acggaaaaat cagtgttcca aatcaaacga ttctttcgtt atttactgtt
    18841 tcagcccttt gaatgttgtc tagaaaaatt aattcccaca tgagaaaaaa gaaatttggc
    18901 tcgttacttt tggttttcag ttgaataaca gataaaaaat tttctggaaa aagtcatcct
    18961 ctgcgtcagc acagtttttt ttgacttatt ttcagaggaa atagttttca gaatattcta
    19021 aaatgtttta tgcaacacta gtgatatttt ttagaattag atttctaatg tgcatttttt
    19081 gagtattaag gagcaagtat acaaagattt ataaagctga ttaaatttga ataaaaatat
    19141 gcaggaacgc tactattttt agtagtgttc ttttttatat ttgaataaaa aatgtggtgg
    19201 ttaaatggtg gttataacaa aaaatgaatt aatgaaatta ggttatggga agtatcagtc
    19261 tgagagaatc atacgacagg caaaagcaat tatggtttca aaaagctata cctattacga
    19321 aaatagaaga ttaggactag tacctgttga atctgtagaa gaagttttag gtatgaagat
    19381 agaggtagag gaggattttc agaatcatgg ttaattttaa aaaagataaa aatgggaaat
    19441 atcattttac tgctagtttg ggattcgaca aacgaacagg gaaaagagta caaaaaaacg
    19501 tagaggggtt aaaacagtta aagaagaaaa aaagcgtata ccgaacttgt ttctaattat
    19561 ggaaaagaag cagaaacttc tcaaagtact atgttgtttg aggagttttt ttataaatta
    19621 ttcctacctt attatcaagg gaaagtagaa gaaagaacat ataaaaatcg gttatctaca
    19681 atcaaaaaaa cttttcttat ttctttaaaa tggagttaag agaaatacgt ccaattgaca
    19741 ttcaaaagtg gcaaaataat ttattgagca aatataaaaa ttcttatgta agaaacatgt
    19801 atgggatttt tcagatgtca ttagatcgag cagttgtttt gggactactt gaaaaaaatc
    19861 ctgcaaaagt tattggaaat gtgaagaaaa ggaaaactac agttgatttt tggacaaaag
    19921 aagaatttac aaaagttatt tcaacttttt atattgatga tttgtaccaa cattttggtt
    19981 ttatttgtat gtggttactt tttatgaccg ttatgcgttt gggagaagcc actgcattaa
    20041 cttggaaaga tattgatttt gaaaataaaa acttgcgtgt gaataaaaca ctctattata
    20101 agagagccaa aacctatgag tttgtagaac ccgaaacggc ttctagtatt cgtacaatcg
    20161 aactagacga caatacaatt acctttttaa aagcttggaa ggagcgtcaa gtttcaatag
    20221 gaggcatgtc gtttgtactt tcttataatg gaacacctac tcagaaatat acaatccgtc
    20281 atattatgag aagacatgca acgatcgttg gtgttcatat aatccgcata cacggattaa
    20341 ggcatagtca tgcttctttg cttatatcac aataaaaaga tgcacttcga attaaagaaa
    20401 ggttaaaaca tgctgatgta caaacgactt taggaactta tggtcatttg tatctaaatt
    20461 cattgagaga gataacaaat gatcccacag attatatcca aactaatttt tctaaaatca
    20521 aaccgacacc tatttacgat aataaaaaat aaatgataaa caaaagtagg atcacaccaa
    20581 aagaaacaca ctagaaaaac tataatacag gcttttctag cgtgttgttt cttatttccg
    20641 cctatttata cattatactc ataaagcatt taatgcatcg atcgtagccg cattgtctat
    20701 atgggtatat aaagttgttg tattggtact tgaatgtccc aattgttggg cagttaatac
    20761 caatgaattt gtctgttggt agagtctagt agctaatgta tgacgcagtt tgtgagggct
    20821 gacttgaatt ctaaagcctt ttgaatattt tgctaccatc cgttcgattg caataccgga
    20881 tatacgcttg gcttctcctt ggtaaattgc tagaaataaa gctttttcgt tttctgttac
    20941 tttatatcgt tctttccgaa tagctagata attagctaaa tattccattg cgaatgctgc
    21001 tatattgaca gcatctcttt tatttccttt tctagttact accacattat tcttatctaa
    21061 agataggtca tctaaattaa tatttataac ctcggagagt ctcaatccag atcctaaaat
    21121 cagtgcattg atcgccaggt ctctttctac atctcgttga taatagatca aagctcgttt
    21181 actcaaagta tttttatatt cattggcaat ataatctaga taattttgtg tatccttatc
    21241 tagaaataat tttttctcaa tggcattggc acgtgcagct aacgtagttt tatctgtgat
    21301 ggttgctact tgatccatag gattattgtc taagtatggt tttcctagag gattattgga
    21361 acttttcgaa agatatttaa atagaacctt taatgccgtg atatttctat tgatagtaga
    21421 agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct ctttttttac
    21481 attttctttt gtgcgacgtt tcaaatgaga tttgtacaag tttaggtcat aggcagttaa
    21541 ctgtcttatc gaggtgatag aagtatcagg aacgatagac tcactcagaa gccattcata
    21601 aaagagctta taatttttta gatattctaa agtggttcga ggtgattgat ctttatcctc
    21661 acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg tatctatttt
    21721 ttgatatatt tctgtatttt tcatgtcatt catcctttca ataagtagg
//
LOCUS       DAFKHN010000047        21280 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFKHN010000047 DAFKHN010000000
VERSION     DAFKHN010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.047"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            157..622
                     /locus_tag="LY912_001754"
                     /pseudo
     CDS             157..622
                     /locus_tag="LY912_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323211.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            965..1221
                     /locus_tag="LY912_001755"
                     /pseudo
     CDS             965..1221
                     /locus_tag="LY912_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            1608..1835
                     /locus_tag="LY912_001756"
     CDS             1608..1835
                     /locus_tag="LY912_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBM6955435.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            1851..3017
                     /locus_tag="LY912_001757"
     CDS             1851..3017
                     /locus_tag="LY912_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBM6955436.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            3252..4295
                     /gene="hrcA"
                     /locus_tag="LY912_001758"
     CDS             3252..4295
                     /gene="hrcA"
                     /locus_tag="LY912_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBM6955437.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            4389..4952
                     /gene="grpE"
                     /locus_tag="LY912_001759"
     CDS             4389..4952
                     /gene="grpE"
                     /locus_tag="LY912_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBM6955438.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            5003..6832
                     /gene="dnaK"
                     /locus_tag="LY912_001760"
     CDS             5003..6832
                     /gene="dnaK"
                     /locus_tag="LY912_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBM6955439.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEVNNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            6983..8149
                     /gene="dnaJ"
                     /locus_tag="LY912_001761"
     CDS             6983..8149
                     /gene="dnaJ"
                     /locus_tag="LY912_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBM6955440.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(8517..9254)
                     /locus_tag="LY912_001762"
     CDS             complement(8517..9254)
                     /locus_tag="LY912_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBM6955441.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(9256..10758)
                     /locus_tag="LY912_001763"
     CDS             complement(9256..10758)
                     /locus_tag="LY912_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBM6955442.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            11017..13011
                     /gene="uvrB"
                     /locus_tag="LY912_001764"
     CDS             11017..13011
                     /gene="uvrB"
                     /locus_tag="LY912_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBM6955443.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            13021..15837
                     /gene="uvrA"
                     /locus_tag="LY912_001765"
     CDS             13021..15837
                     /gene="uvrA"
                     /locus_tag="LY912_001765"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBM6955444.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            16100..17365
                     /locus_tag="LY912_001766"
     CDS             16100..17365
                     /locus_tag="LY912_001766"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBM6955445.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            17369..18100
                     /locus_tag="LY912_001767"
     CDS             17369..18100
                     /locus_tag="LY912_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBM6955446.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            18235..19119
                     /gene="rapZ"
                     /locus_tag="LY912_001768"
     CDS             18235..19119
                     /gene="rapZ"
                     /locus_tag="LY912_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBM6955447.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            19116..20114
                     /locus_tag="LY912_001769"
     CDS             19116..20114
                     /locus_tag="LY912_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBM6955448.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            20148..21083
                     /gene="whiA"
                     /locus_tag="LY912_001770"
     CDS             20148..21083
                     /gene="whiA"
                     /locus_tag="LY912_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBM6955449.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
BASE COUNT         7073 a         3657 c         4612 g         5938 t
ORIGIN      
        1 aaaagtaatt ttgtaaagat tcatttattt gaaacattta aaccaaaaga acacacatat
       61 ctgggagaag tatatttagc aggacaaata tatactgtta atgaaaaaga tagttcgggc
      121 aacagcagaa aagtatataa atttccatta gctttaataa atcaagagca attgattgaa
      181 gataaagata tataaccagg aagaaaatca aactagacat attcgtaatt tatctaatgc
      241 taaattagag gaagaagcaa gaaaagttag taattataat aaaaaaatgg ctgcaaaata
      301 tgttaacgaa gaggagtttt gcttctcaaa aacaaaaata tataaacgta atcccttcgt
      361 atctgaatat gttaaacgac ttgcaaaagg tatttgtcaa ctttgccaag aaaaagggcc
      421 atttataaaa gacggtgtac cttatttaca ttgtcatcat atagaatatt tgtcgcaagg
      481 tggaaaagat gtgattgaaa actgtatcgc gttatgtccc aattgtcatg ctagaattca
      541 tgaacttgag ttacctgacg ataaagaaaa attgctgaag atcgttgaaa aaagagaaaa
      601 tagcttttct aaaataccgt aatttatttt tataggacaa ataagctaat gtgagctatg
      661 ccttctatat aagactaagt tctattataa gtaacgaagt aattctcgtt ccttcctgta
      721 gtaatatttt ttaaataacc tataggcttc ttcaaaagta catcctccag taaattctaa
      781 gtactggagg attctttttc tagtgttgct ttactcatga aaaagtagtt ggctacttca
      841 tcaaaatttc tgaacttttt taatgtataa taaagagctc gatcatttac tacaaggatg
      901 ctagctccta cattttcaca gttttttagc aagtaaattt ttctaaaatc acatcaggaa
      961 atgcatgaga ttctttaaga gaggcaatta tagggctatg attacggttc gtgtaagtga
     1021 cgccaaaaaa gaatggcttt cttatatggc tgaattttat gggattactt tatctgaact
     1081 tctaaaaaac tattcgatgg aacaactaga agatgaatac aatcgtcaaa cggctgaaat
     1141 tgcccataaa cattggataa gaagtgggaa aacaacagta ttcatggaag aatccttaat
     1201 gaatttggtg ggctggaatg acctgccgtt taaaattcac gcccgaaatt cagaagcagc
     1261 tctgattggc aaatacgtgt attggtagag atagaagata atcaattcgt tgttatcgct
     1321 attcaagtag ggcaccgaag aaatgtctat gattaagaga ctgtttattt ttacaaaaaa
     1381 ataataattg gaatctagtt aaaactcttg aagtgagaga tttgactaga tttttttatg
     1441 aataaaataa ggacaaaatt gtttaggaag aatcatgagt gtaaaaaaat catccaagaa
     1501 gtcgattctt ggatttttta gtggatttgt tcgccaaata cgtttagtat gcgtatatga
     1561 gaggttgtaa gcaaagcgtt gtggtctgag cacttaagga ggaatctgtg aaaatagctt
     1621 ttcatatttt tgcagatttt gacttaatgc cgaaggtcag ctttgcgatt accgtttatc
     1681 gagaggctgt aaaagcaccg tgtagctccg atgacaataa gcaagcattt ttagagctag
     1741 gtttccttga ttctaaatat gcggcttatt tcaatgagtt ggtgcttgaa cgcgatttta
     1801 agaaggtcga aaacaggcac gacttttcga cgtaaggaga aagaatttca atgatagaaa
     1861 caataaatcc cgcagaaaac aaggtttctg cgtacattca tatcccattt tgcgagcata
     1921 tctgctatta ctgtgacttt aataaagttt ttttagaagg gcagccagta gatgagtatg
     1981 tggaaatgct gctgaatgaa atgagattaa tgctggaaag tcatcctaca gcgaatttgg
     2041 aaacacttta tgtaggaggc ggaacaccaa cttctttatc tgctaaacaa cttgatcgac
     2101 tattatcagg tgctagagag atcctgcctt ttcaaaatgg taatgagttt actgtagaag
     2161 cgaatcctgg tgatttgacc cgtgaaaaac ttcaagtgat gaaaaactat ggcgtcaatc
     2221 gtttatccat gggagtgcag acatttgaca atcgcttatt gaaaaaaatt ggacgtaaac
     2281 atactgcaga agatgtgtat caaacaatgc aatttttaga agcagaaaat tttaccaatg
     2341 taagcatcga tttgatttat gcattaccgg gacaaacact agaaggatat cgggatactt
     2401 tggaaaaagc tttggctttg gatctgcctc actattcttt gtactcattg atcctcgaaa
     2461 acaaaacaat gttcatgaac tgggtacgac aaggaagact cgaactgcct gatcaggaaa
     2521 cggaaaccag aatgtttgaa gagacgattg aagcaatgga aaagcatgga cgtcaccaat
     2581 atgaaataag taactttggg ctctccggac atgaatctca acataacctc atgtactgga
     2641 acaatgacca ctattttggg tttggagctg gtgctagcgg ttatcttgga gatattcgtt
     2701 accgcaacaa aggaccaatc caacactatt tacgcccatt acgagcaaat gaacgcccgg
     2761 tattggaaga agaaaaattg acacgaaaaa atcaaataga agaagaaatg ttcttaggac
     2821 taagaaaaaa aacagggatt actaaaaaac atttctatga tcgctatcaa aaaacaattg
     2881 aatcggtgta cggtgatgtg ctaagggaat tagagcaaga agggttactt gttaatgaag
     2941 aagaccgtgt ttatttgaca ccaagaggga cttttttggg gaacaatgtg tttgagcgct
     3001 ttttatttga aaaatagttt gaagaatatt tgttttttat cgaaacttga aaagaaaaag
     3061 tttagaaagt ttgacaatga ggtattgaag tattgatata actggattta catcaattat
     3121 ttagaattag cactcttgtg tttagagtgc taaaaaatgg agtctttctc ttgacaggag
     3181 aagggcttct tgctatattt ataagtgaat tagcacttag aatatatgag tgctaatgag
     3241 aggtgaggaa gatgttaaca aagcgacaaa acgacatttt acgtctgatc atccaacact
     3301 atacgagtag tggcgtgccc gttggttcca aaacattaat gtctgaggga gtcaaggcca
     3361 gctcagcaac gattcgcaat gatatgaaag cattagaaga tgaaggattg ctgttgaaga
     3421 ctcactcttc ttctgggcgg attccatctg ctttaggcta tcgttattac gtggatcatt
     3481 tgttaaaacc tgctcgcgta gcagaagatg atttgctgct gattcgtcag tctctaggca
     3541 gagaatttca tgaaatcaat gagattatta agcaatctgc tgagatatta tctgagctga
     3601 caagctatac gactttttca ttgggacctg aaataaaaga ccgccgactg actggctttc
     3661 gtatcgtacc cttgaataat cgacagatta ttgctatcgt cgtaacagat atggggaatg
     3721 tagaaagcca agtgttcact cttcccgaat atatgggaag tcaggaacta gaaaaaatgg
     3781 tacagattgt aaacgaccgt ctagtcggag atcctctgat gacggtgtac cataaacttc
     3841 gtacggagat tccgatgatt cttcataaat atttccagac gacagaaggg atgtctcagt
     3901 tatttgacac cgttcttggt catgtttttg aagaaaaggt ttatgtcagt ggacaaatga
     3961 atctcttgga ttatgagccc cgtcaagatc ttgatcagtt caaatcgatg ttttctttta
     4021 tgaaagactc agacggactt acacaaatga tcactccgat ggatagcaat attcatatca
     4081 agattggtgc tgaattaggc aatgatttat tgcagaatat gagtatgatt caagcaagtt
     4141 acgagataga tggtcatgga agaggtacaa tagccttgtt agggcctact agtatgcctt
     4201 attctcggat gttcggtcta gtcgatgttt atcgaagaga actagcagct aaacttgctg
     4261 attactaccg ctcgcttgac ttgtcaaact cgtaatgtga ataacgaagc tatttgcagc
     4321 tgatcgttct ctctttctta gtaagagcaa tcaaacagct gactgaataa tgaaaggaag
     4381 actgtatcgt gaaagaaaat caagaagaac tagataaaga aatgacagat gctcagccag
     4441 aaccggaaat cgatgtcgaa gctgcagaag attcgggtat ttcagaagct gaagcggaag
     4501 aattcgaaac agcgaaatta aaagctgagt tagaagaaat ggaagataaa tacttgcggg
     4561 ctcgtgctga aatcgcaaat atggcaaatc gaggaaaaaa tgagcgtgag caattacaaa
     4621 aataccgttc acaagattta gccaaaaaat tacttccatc aattgacaac ctggaacgtg
     4681 cattagccac agaagtgtca gatgatcaag gggcaggttt gaaaaaaggc gtggaaatgg
     4741 tcttggaaag tttgcgtaac gcactggaag aagaaggaat tgaaaaaatc cctgctaaag
     4801 gagaagcctt tgatcctaat cttcatcaag cagtacaaac tgttccagcg actgaagata
     4861 caccagccga tacgattgta gaagtactac aagaaggcta caaattacat gatcgcgtgt
     4921 taagaccaac tatggtcatt gttgcacaat aattgtgcgg atataaaact tacactttca
     4981 attaaagaag gagacgttaa ttatgagtaa aattatcggt attgacttag gtacgactaa
     5041 ctctgcagta gcagtattgg aaggaaacga agcaaaaatc atcgctaacc cagaaggaaa
     5101 ccgtacaaca ccttctgttg tatcattcaa aaatggagaa atccaagtag gggaagttgc
     5161 aaaacgtcaa gctgtgacaa acccaaatac gatttcatca atcaaacgcc atatcggtga
     5221 agcaggttac aaagtagatg tagaaggtaa atcatataca ccacaagaaa tctcagcaat
     5281 gatccttcaa tatatcaaag gattcgcaga agactattta ggtgaaaaag tcgaaaaagc
     5341 agttatcact gtgccagctt actttaatga tgcacaacgt caagcaacaa aagatgctgg
     5401 taagatcgct ggtctagaag tagaacgtat cgtcaatgaa ccaactgcag ctgctcttgc
     5461 ctatggttta gataaaacag atcgcgacga aaaaatctta gtattcgacc ttggtggcgg
     5521 tacttttgac gtatctatcc ttgaactagg agacggtgtc tttgatgtat tgtcaacagc
     5581 tggcgacaac catctaggtg gggacgactt tgataacaaa atcatcgact acatggtagc
     5641 agaattcaaa aaagaaaaca gcattgactt gtctcaagac aaaatggctt tacaacgctt
     5701 gaaagacgct gctgaaaaag cgaaaaaaga tttatctggc gtatcaagca cacaaatcag
     5761 cttgccattt atcacagcag gagaatctgg accattgcat ttggaaatga cattgacacg
     5821 tgcaaaattt gatgaattaa cagctgactt agtagaacgt acaaaagtac cagtacgtca
     5881 agcgttaaaa gatgcaggtc tgtcacaatc agaaatcgac gaagttattt tagtcggtgg
     5941 atctactcgt atccctgcag ttgtagaagc agtacgtaaa gaaacaggaa aagaaccaaa
     6001 caaatcagtt aaccctgatg aagtagttgc tatgggtgct gctatccaag gtggcgtgat
     6061 cactggtgat gtgaaagatg ttgttttact tgacgttaca ccattgtcat taggtatcga
     6121 aacaatgggt ggagtgttca ctaaattgat tgaccgcaat acaacgattc caacaagtaa
     6181 atcacaagta ttctcaactg cggcagataa tcaaccagca gtagacatcc atgtattaca
     6241 aggtgaacgc ccaatggctg ctgacaacaa aactctagga agattccaat tgacagatat
     6301 tccagcagct cctcgtggta ttccacaaat cgaagtaaca ttcgatattg ataaaaacgg
     6361 gattgtaaat gtatctgcga aagatctagg tacacaaaaa gaacaaaaaa tcacgatcaa
     6421 atcttcttca ggtctaacag acgaagaaat cgaacgtatg gtgaaagatg cagaagcaaa
     6481 cgctgaagca gataaagctc gtaaagagga agttgaccta cgtaatgatg tagacgcatt
     6541 gctattctct gtggacaaaa cattgaaaga attagaaggc aaagtggacg aagaagaagt
     6601 gaaaaaagca gaaacagctc gtgacgaatt aaaagccgct gttgaagtaa acaacatcga
     6661 ggaaatgaaa actaaacgcg atgcattgaa cgaaatcgtt caaaacttga ctgttaaact
     6721 atacgaacaa gctgcacaac aacaagctca agaaaatcca gaagcagctc aaggcggagc
     6781 agatgatgtc gttgatgctg attttgaaga agtcgatggc gacgataaat aatcagttca
     6841 ctgaatttcg agagaaggcc aaagttgcta ctttggcttt ttcttttgaa aaatagtttg
     6901 aagtatcggt ttttgtttca aacaaaatat gatatgataa caagcgacgt gaaaatgatg
     6961 agaaccaata ggaggaaagc ctatggcaac aaaacgtgat tattatgaag tcttagggct
     7021 ctcaaaagga gcatcagaag atgaaataaa gaaagcttat cgtaagcttt cgaaaaaata
     7081 ccatcctgac atcaataaag aacctgatgc ggaagaaaaa ttcaaagaag tatcagaagc
     7141 atatgagatt ttaagtgacc cgcaaaaacg cgctgcatac gaccaatacg ggcatgcagg
     7201 cacagatcca aattacggtg ctggtggagc tggtggcgga tttggtggat tcggcggctt
     7261 ctctggtggc ggcttcggtg gttttgaaga tatcttcgac tctttctttg gaggaggcgg
     7321 tcggtcagtc gatccaaatg cgcctcgtca aggtgctgat ttgcaatata cggtcgactt
     7381 gtcttttgaa gaagcgattt ttggtgtaga aaaagaaatc aagtataatc gggaagaaat
     7441 ctgtcatact tgtggtggaa acggtgcaaa accaggcaca caaccaacta cttgtcataa
     7501 atgtcatggt gcaggtacga tcaatgtaga acgccaaacg ccacttggac gagtgatgag
     7561 ccgtcaaact tgtgatgttt gtcatggcac agggaaagaa atcaaagaac cttgtccaac
     7621 ctgtcatggc tcaggacatg agaagaaagc acattcagtt aaagtgaatg taccagctgg
     7681 tgtagaagaa ggacaacaaa tgcgtttagc tggtcaagga gaagctggag aaaacggcgg
     7741 accatttggt gatttgtatg tggtttttcg tgtagaagaa agtgatatct ttgatcgtga
     7801 aggttctgaa atttactatg aattgccttt aagttttgta caagcagctt tgggggatga
     7861 agtccaagta ccaactgtcc atggagatgt gaaattgaag atccctgctg gaacacagac
     7921 aggtacgaac ttccgtttac gtggaaaagg cgctccgaag ttacgtggtg gtgcaacagg
     7981 cgaccaacat gtcaaagtaa aactgatcac accgaaaaat ctaaatgaac aacaaagaga
     8041 agcattacgt gcattcgctg aagctggcgg catcaaagtt gaagaacagc aagaagacgg
     8101 tttcttcgat aagtttaaag atgcttttgg cgggaaaaag cggaagtagt ttttctagta
     8161 aaaatataaa gtagacttgc ccaaattttc tatttctagt aaaaacgcta agtcattaat
     8221 aattaaaaac cagacgaaca atcatacgtt cgcctggttt ttttgtagtt gtcatgtttg
     8281 taccaacaaa aaagccagct ttagaataag ataatcatca tagtttctga aggtggtatc
     8341 gactatgtac ttgatatcgt caatgaaccg atggtacttt cttatgcgat ggaacaggta
     8401 gagcgattgc ttgtttgtgc aggagaacaa gcgatgcggc tggtacagtt aagtgaaaaa
     8461 acaagaaact aaaaatgccc ggtcgtcatg aagcgaccgg gcatttttgg tttttattaa
     8521 atatttaata ctttattcaa gaaatctttt gtccgttcat tttgcggatt ttcaaagatt
     8581 tgttgaggcg ttccgtcttc taaaaagttt ccgtcgtcaa tgaacatgac acgattggcc
     8641 acttctttag cgaagcccat ttcgtgcgta acgataacca tcgtcatacc ttgttctgct
     8701 aactttttca tgacgttcaa gacatcaccg accatttcgg ggtcgagtgc agatgtaggc
     8761 tcatcaaaaa gcatgatgtc agggttcatc gctagagcac gagcaatagc cacacgctgc
     8821 ttttgtccac cggaaagcat ttcaggatac atatcttttt tatcttctag accaactgtc
     8881 tgcagcaatt tgattgcttt tttctctgct tcttctctag attctttctt caggtccatc
     8941 ggtgctaaaa tgatgttttc caaaatagaa agatgaggga ataggttaaa gtgctggaat
     9001 accattccga tatgttgtct caccaagttg atatctgtgc ttttatccat caagtgggcg
     9061 ccgtcaataa taatttcacc gtcagaaggt tcttctaaac gattcaagca acgcaaaaat
     9121 gtactttttc ctgaacctga agggccaatg atacagacga catctccttc gttgatggac
     9181 acattgatgt cgtttaatac tgtgttatcg ccgtattttt tgactaaatg ctcaactaag
     9241 attttttctg ccatcttact tcaccttctt ttctaaaact tttgctaatt ttgtcaatgc
     9301 tgtgatcaaa atcaagtaca tgatcgcaat gatcaagtaa acatacgtac tttgtgttgt
     9361 acgtgcaaca atgatcttac cagtttgcag caattcgact acaccgattg cggaaatgat
     9421 cgttgtgtct tttaatgaga taacgaactg attgacgaat gatgggatca tgatgcgtat
     9481 cgcttgcggc aaaatgattt tttgcattgt ccgattataa gaaagaccta aacttctgga
     9541 agcttccatt tgtccgacag gaacggcgtt gatcccgcct cgaacaatct ctgcgatata
     9601 agcacttgcg ttaagagtca aggtgataac accagcaagg aagtcaggaa tcgtaaatcc
     9661 aacgatacca ggcaacccaa agaaaataaa gaacgcaaga accatcattg gaattcctcg
     9721 gatgatatcg acataaatac tagcaattgt gcgaagagcg cgtattggtg ctacactgaa
     9781 taatccaaaa atcacaccga ttactatagc caaagcaaag gagatcaaag ttaggagaat
     9841 tgttctccaa agtcctttca acaatgcttg atagttgttt tggataagtc caagaaatgt
     9901 tgattcatca gcagtggaag actcactgga agtttctgaa ccatccgcta catattcttt
     9961 aataatctta tcgtattcgc ctgttctttt taattctttc aatccttcat tgaacatatt
    10021 aagaagctca ggattttgtc cttttttaac ggcaaatgca tattttccgc cagattcttt
    10081 tttgatcggt gtttccaatt cttgtccttg tttgatcgca taaccgatta ccggataatc
    10141 atccatcatt gcatcgattg cgccaacttt taacccgtcg tacaattgat cagcagcatc
    10201 aaaatatttg atagaatagc catattcaga ttcatggtcg cttaaaaatt cagcactttc
    10261 ggtaccaact tttgctccga ctgtttttcc tttcaaatct tcataagact tgatcgaagt
    10321 atctcctttt ttgacagcta attggatccc gctatcaaag taagaatcag aaaaatcata
    10381 gcttttcttt cgttcatctg ttacagtcat tccggcaatc attccgtctg cttgtcctga
    10441 ttccaaagct tgcaaagcag cagagaaacc acggtagtcc attcggatgt taaatccttg
    10501 cagtttggcg atgttttcca tcaattttac atcgatgcct tcgtactcgc cctttgcgtt
    10561 ttgaaattca aatggagcaa aagcagagtc actggcaatt acgtatacgt cttttttggg
    10621 ctctattttt tgcattgtct cgcttgtgct tgactctgcc gttgtagtgt tgtcagcttg
    10681 tgcaacatgt ccaaacgcaa gtgtcacaag tcctgtcatt aagaaaacaa atgagtgaaa
    10741 taaatgcttt cttttcataa tcaacctcct aaatttccaa tattttatta ttataggcga
    10801 aaagtgctga atcagacaag actgtaagct cgaaaaaatg aaaaaaatgc gagtttctaa
    10861 cattttatgt tataaaacgt aacatgcata ataagataaa aaagtggcga aagtatgttc
    10921 ggtgtggtat aattttttag taaggaatgc ctttgctttc cttttctttt tattggtcgt
    10981 aaaatgaaaa ggaatgaatg aaaaggagga cgaagaatga ttgagagaga tacctcccga
    11041 cactttgagc ttgtctcgaa ataccaaccg gctggtgatc agcctgaagc gattaaccaa
    11101 ttagtggatg gcgtagtcgg cgggaaaaaa gcacaaatct tattaggtgc gactggaaca
    11161 gggaaaacat atacgatttc caatcttatt gagaaagtga ataaaccaac actaattatt
    11221 gcccataaca aaacattggc tggtcagctg tacggggaat tcaaggaatt tttccctaac
    11281 aatgctgttg aatattttgt ttcttattat gattattatc agcctgaagc ttatgtgcct
    11341 tcaagcgata cgtatatcga aaaagattca agtgtaaatg atgagatcga caaattacga
    11401 cattcggcta ctagttcatt attagaaaga aatgatgtga tcgtcattgc atccgtttca
    11461 tgtatttttg gattaggttc gccttttgag taccaaaaac aagtagtttc gattcgacag
    11521 ggagcagaac tagatcgcaa tcagttgatt cgtgacttag tcagtatcca attcgaaaga
    11581 aatgatatag attttcagcg cggtcgtttt cgagtgcgcg gtgatgtcgt ggagattttt
    11641 ccggcttcaa gagatgaacg tgccttacgt gtggagtttt ttggagatga ggtcgaacgt
    11701 atccgagaag tcaatgcact gacaggtgaa gttttaggag aaacggaaca cgtggcaatc
    11761 ttcccggcga ctcactttgt gacgaatgat gaacatatgg agcatgccgt agcgaatatc
    11821 aaagcggaat tagaacagcg tttaactgtc ttgcgaaatg aaaacaaact tctggaagct
    11881 caacgtttag aacagcgaac caattacgat attgaaatga tgttagaaat gggctacacg
    11941 tcgggaattg aaaattattc tcggcatatg gacggacgta aagaaggtga accgccttat
    12001 acgctattgg atttctttcc tgaagatttt ttgatcgtgg cggacgaatc gcacgtaacc
    12061 atgcctcaag tcagaggaat gtataatggt gaccgagcga gaaaacagat gctagtagat
    12121 tacggtttcc gtttgccatc tgctttagac aatcggccac ttcggttaga agagtttgaa
    12181 aaacatgtca atcagatcat ttatgtctct gcgacgccag gaccatatga acatgaacaa
    12241 acagataccg ttatccaaca aatcatccgt ccgacagggc tgcttgaccc agtgatcgaa
    12301 gttcgtccaa tcatgggaca aatcgatgat ctagtaggcg aaataaatga acgagtcgaa
    12361 aaagaccagc gggtgtttgt aacgacattg acgaaaaaaa tggcagaaga cctcacagat
    12421 tatttcaaag aattagggat caaagtcaaa tatttgcata gtgatatcaa aacgctggaa
    12481 cgaacagaaa tcattcgaga tcttcgatta ggtgaatttg atgtgttagt tggaatcaat
    12541 ttgcttcgtg aaggattaga cgtacctgaa gtttcccttg ttgctatctt ggatgcggat
    12601 aaagaaggct ttttacgtag tgaacgttcc ttagtccaaa cgattggacg agctgctcgg
    12661 aatgaagaag gtaaagtaat catgtacgca gacaaagtaa cagattctat gcgtctagcg
    12721 atggatgaaa catcaagacg ccgtacgatt cagcagaagt acaatgaaga acatgggatc
    12781 gttccaaaaa cgatcattaa agaaatccga gatttgattt ctattacgaa agaatcggaa
    12841 gatgatacaa aagaagcggt acaagtctcg tatgaagaaa tgacgaaaga agaaaaagat
    12901 acgttattga tgaaattaga aaaagaaatg aaaaatgcgg cgaaagcatt ggattttgaa
    12961 acagccgcta atgtgcgaga tatgatttta gaattaaaag cttcaaagta ggaggacaac
    13021 atggctaacg ataaaattac gattcacggt gcacgtgccc ataacttgaa aaatatagat
    13081 gtaacgattc cacgagataa attcgtggtc gttacaggtt tgtccggttc tggaaaaagt
    13141 tccctagcat ttgatacgct gtacgctgaa gggcagcgga gatacgtaga gagcctttct
    13201 gcttatgctc gtcagttttt aggacaaatg gataagccgg acgtagatag catcgacgga
    13261 ttgagtccgg cgatttctat tgatcagaaa acaacaagta aaaatcctcg gtcgacagta
    13321 ggtactgtga cggaaatcaa tgactattta cgcttgttgt ttgcacgtgt aggacatccg
    13381 atttgtccca acgatcatat cgagattacc agtcaatcag tagatcaaat ggcagatcaa
    13441 gtaatggctt tgcctgagcg cacaaagatc caagtgttgg caccgatcgt ggtaaagaaa
    13501 aaaggacaac ataaaaaaat attcgaacga atccaaaaag agggatacgt ccgcgttcga
    13561 gtcgatggtg agatctatga tttaagtgaa gtgcctgagc tggagaaaaa caaaaaacat
    13621 gatatcgcga tcgtcatcga ccggatcatt gtgaaagaag ggattcgttc tcgtctattt
    13681 gattctttag aggcggctct gcgattggca gacggctatg ctctggttga cgtgatcggt
    13741 gaagaagaaa tgttgtttag cgaacactat gcctgtcctt attgcggatt tactgttggc
    13801 gaactagaac caagactgtt ctcattcaat gcgccttttg gagcttgtcc agactgtgat
    13861 ggtttaggtg tcaaattaga agtcgatcaa gatttagtga ttccagatag aacgaagaca
    13921 cttagtcaag gtgctatcgt tccatggaat ccaatcagct ctcagtatta tcctcaaatg
    13981 ttagcgcagg cttgtgaaag tttcggtatc gatttagata caccattcga agaattaccg
    14041 gaagagcatc aggatatcat cttgaatggg acagatgatc ttttccattt ccattatgaa
    14101 aatgattttg gtggcgttcg cgatgtagaa acgactttcg aaggggtatt gaagaatatc
    14161 gagcgtcgtt atcatgatac gaacagtgat ttcacgcgtg agcaaatgcg tctttatatg
    14221 acagaattaa cttgtcagac atgtaaaggt tatcgattga atccccaagc tctatctgtt
    14281 caaatcaatg gaacgaatat cgggcaaaca aatgagttgt ctattcaaaa agcagtagat
    14341 ttcttctcaa acttaacgtt atctgaacaa gagaaagtaa ttgccaaacc gattttaaaa
    14401 gaagtaaatg acagactttc attcttggaa aatgtgggac tagactatct aactttgagt
    14461 cgcgcttccg gaacattatc tgggggagaa gcgcagcgaa tcagattggc tacacaaatt
    14521 ggatcgaatc tttctggagt tttgtatatt ttagatgaac catcgatcgg attgcatcaa
    14581 cgcgacaacg atcgactgat tggctcatta aagaaaatgc gtgatcttgg caacaccctc
    14641 gttgtagtcg aacatgatga agatacgatg tgggcagcag attatctgat tgacgtcgga
    14701 cctggggccg gagaacaagg cggacaaatc gtggctgcag gcactcctga agaagtagct
    14761 aatgatgaaa attctttgac agggaaatat ctttcaggga aaaaatcaat ccctgtacca
    14821 aaagaacgcc gtaaaggtaa tgggaaagca atcaagatca ctggtgcttc agaaaacaat
    14881 ctgaaaaata ttagtgttga atttccatta ggagaatttg tagcagtcac aggtgtgtct
    14941 ggttctggaa agagtacatt ggtcaatagt atcttaaaga aatcgttagc gcaaaaatta
    15001 aataagaatt ctgctaagcc aggtaaattc aagacaattt ccggctacga aagtatcgaa
    15061 aagatcatcg atatcgatca aagcccaatc ggccggacgc cgagaagtaa tccagcgact
    15121 tatacaagtg tatttgatga tatccgtggg ttatttgctc aaacgaacga ggcaaaaatg
    15181 cggggttata agaaagggcg ttttagtttc aacgtaaaag gcggtcgttg tgaagcttgt
    15241 cgcggggatg gaattattaa gatcgaaatg cactttttgc ctgatgtcta tgttccttgt
    15301 gaagtatgtc atggcaaacg atataactct gaaacattag aagtgcatta caaaggaaaa
    15361 agcattgctg atattttgga aatgacagta gaagatgctg tagaattctt caagcacatt
    15421 ccaaagattc atcgcaaact gcaaacgatt gttgatgttg gcttaggtta tgtgacgatg
    15481 gggcaaccag caacgacatt gtccggtggt gaggcacaac ggatgaaact tgccagtgaa
    15541 ttgcacaaaa tctctaatgg aaagaatttc tatatactag atgaaccaac gacaggactt
    15601 catagcgatg acatcgcccg cttgttgcat gtattacaaa gattagtaga tgctggtaac
    15661 acagttttag tgattgaaca caatctagat gtaatcaaaa cagcagatta tatcattgat
    15721 ttaggaccag aaggtggaga aggtggagga acgatccttg cgactggaac accagaagaa
    15781 atcattaacg taaaagaaag ttatacaggt cactatttga aaaaaataat ggtataaaga
    15841 ggatagatag ctgagatagt taaaaaaaca taaaaaaatg aatttttgct tgttttatta
    15901 atatcagtgt tctagaatca ttacatggta gttctttcta cactgattgg tatagacaaa
    15961 aacttcctat aagttcaatc cgttcaaaaa agaattgagc aatcggagga gtttcctttg
    16021 attgcttttt tctttatggt atgatattcc ttgtgtagtt ggaaaagaaa aacaagagat
    16081 tatgagtaag tgagagataa tgatgaacag tattgaaaat gaagaattta tccctatatt
    16141 attaggaagc gacatgaacg tttatggtat ggcacgttct tttaatgaag catacggcaa
    16201 aatctgccaa gcatatgctt cggatcagtt agcccctacc cgctacagta aaattgtcaa
    16261 tgtagaagtt attccaggat ttgataaaga ccctgtgttt atcgagacga tgcttcgttt
    16321 ggcaaaagaa agatattctg ataagagtaa aaaatatctt ttgattgctt gtggtgatgg
    16381 atatgcagaa ttgatctccc aacataaaca agagctgtca gaatatttta tctgtccata
    16441 tattgattat tctttatttg aaagactgat caataaagta agcttttatg aagtttgtga
    16501 agaatatgat cttccgtatc ctaaaacatt gatcgtcaga gaagaaatgt tagtaaatgg
    16561 acatttggaa caggaattgc cttttgaatt cccagttgct ttgaaacctg caaacagtgt
    16621 ggagtatctt tctgtccaat ttgaaggaag aaaaaaagct tttattttag agactagaga
    16681 agagttcgat ttaattttag gccggatata cgaagccggt tataaaagtg aaatgattgt
    16741 acaagatttt atcccgggtg atgatagtaa tatgcgtgtg ctaaatgcgt atgtagatga
    16801 agatcatcaa gttcggatga tgtgtcttgg tcatccactg ttagaagatc ctacaccagc
    16861 atcgattggt aattacgttg tgatcatgcc agattataac gaaaaaatct atcaaaccat
    16921 taaggcattt ttggaaaaaa tcgaatatac aggctttgcc aatttcgata tgaagtatga
    16981 tcctagagat ggagaatata aattatttga aatcaatttg agacaaggtc gtagcagttt
    17041 ctttgtgaca ttgaacggct tgaatctggc tcgtttcgtc acagaagatc gagtgtttaa
    17101 caaacccttt gttgaaacga cctatggaac gaatcaatca gataaagcaa gattatggat
    17161 gggtgtgccc aaaaaaatct ttttagaata tgctcgggaa aatgaagaca aaaaactagc
    17221 tgagcaaatg atcaaagaaa atcgttacgg tactactgtg ttttatgaaa aagaccggtc
    17281 aatcaagcgc tggttgttga tgaaatatat gttccataac tatattccaa gattcaaaaa
    17341 gtattttcat gtgaaagaag gctagttcat ggagaatttt ttcagtattt taggcggaat
    17401 gggcacgatg gcgacagaaa gttttgttcg cttgatcaac caccgaacga aagctacaaa
    17461 agatcaagaa tatttgaatt atgtcttatt caatcatgca acagttcctg atcgtacagc
    17521 ttatatttta gatcgatcag aagaaaatcc aatgccgttt ctgctggatg atattgagaa
    17581 acaaaattta ttgcagccga acttcattgt gttgacttgt aacaccgcac actacttttt
    17641 tgaagaatta caagcggcaa cggatattcc tatccttcat atgccaagag aagcagcaaa
    17701 tgaacttgtc cgtcagcata cgacagggag agtagcgatt ctaggaacag aaggaagtat
    17761 gaaagctgga atctatgaac gcgaagtcaa aaatcttgga ttcgaaacag tgattcctga
    17821 tactgttctt caagaaaaaa tcaattatct gatctatcat gagatcaagg aatcggatta
    17881 tttgaatcaa gagctatatt acgaaatctt agaagaagcg gtagagcgcc taaactgtga
    17941 aaaagttatc ttaggttgca cagaattgtc attgatgcat gaatttgctg aagataacca
    18001 ttatccagtg atcgatgccc aatctatttt agcagatcgg acgattgaac gagcgctagc
    18061 tgaaagaagc aaggcattgg atacagcatc ggaaaagtaa aaaaattgga tttggggcaa
    18121 atatcctaaa agatatttgg tccaaatctt tttgtaaaag aaaaagaaaa ctggtaatga
    18181 tacgcccgga atgatataat tttactatgc acaatgtgag aggagttcgt aattatgaca
    18241 gataatttgc aattagtcat cataacaggt atgagcggtg cagggaaaac agtagctatc
    18301 caaagttttg aagatatggg ctatttttgt atcgataata tgccgcctcg attgattcca
    18361 aaattctggg aattaatcaa agaatcaggc aaagtcacaa aaatggcttt aggagtggat
    18421 ttacgttctc gttccttctt tgaagaaatc caaaacatgc tgatcgaaat cgaaaatacg
    18481 aacttcatcg acacttctat cttattttta gatgcttcag acgaagaact agtggctcgc
    18541 tacaaagaaa caagacgagc acatccaatg gcgatggacg gtttgatcac tgaagggata
    18601 cgtaaagaac gggcgatact agacgacttg aaagcccaag cttccgtgat cattgatacg
    18661 acgacattga caccacgaca attacgtgaa aaaatcaatg agtcattcaa atcaaaggga
    18721 gaccaaggat ttcggatcga atttgtatca tttggtttta aatacgggtt gccgatcgat
    18781 tcggatattg tgatggatgt gcgttttttg cccaaccctc attatatccc ggaactaaga
    18841 ccattgaccg gaaaagatca gccagtctat gattatgtga tgtcctttga tgaaacgcaa
    18901 tcattctacc ataaattttt ggatcttctg gaaactgtat tgcctggata cattaaagaa
    18961 ggaaaaagca gcttgacagt tgcaatcggc tgtacaggcg gtcaacaccg ttctgtggca
    19021 ttgactgaac gtttggcaaa tgctttaggg aaaaactata aagtcaatgt gacacatcgg
    19081 gacaaggata aaaggaaaga gacggtgaac cggtcgtgaa aatgaaaacc taccggataa
    19141 gaaaaccaaa gatcgtagtg gtcggcggtg gcactggtct gccagttatc ctgaaaagtt
    19201 tgcgaaatca aggagcagat atcacagcag tagtgactgt tgcagatgat gggggaagca
    19261 gcggtgcaat cagagaatcg atcgctatgg ctcctcctgg tgacttgaga aatgtcttag
    19321 tggcgttatc ggatatgcca caattctatg aagatatttt ccaataccgt ttcaaaaagg
    19381 aagatcagtt tttagccaat catacgatcg gtaatctgat cattgccgca gtttccgaga
    19441 tgcggggaag cacttatgag gcgattcaat tattagcaaa aatgatgcat gtagatggac
    19501 atgtttatcc ttcttcagaa actcctttga ccttgcatgc tgtctttaaa gacggaacga
    19561 ctgcagtagg agaatctaaa atcgcgatcg accgtaaaac cattgaccgt gtgtatgtct
    19621 gcaacacaaa tgataaaagt gaagccaaag cggctcgaaa agtcgtttca gcaattatgg
    19681 acgccgacat ggtcgttttg ggacccggaa gtttattcac cagtatcctt ccaaatttag
    19741 tgataccaga aatcggcgaa gcaatgctca agacaactgc tgaaaccgtc tatatctgta
    19801 atatcatgac ccaaaaaggg gaaacggaac atttcacaga tgccgatcat atacgtgttt
    19861 tacacaagca tttgaatcag ccttttatcg atacagtatt ggtcaatacg gaaaaagtgc
    19921 ctgaagatta tatggaccca gagatctatg atgagtatct agtacaagtc gcacacgact
    19981 tcaacggatt gagaaatgaa ggatgtcgag tgatttccac cgactttttg gaattgaaag
    20041 atggtggtgt cttccacgat ggagacaaag tagtagaaga attgttccgt ttagttttcg
    20101 gttcaaaata ttaagcaatt tattgttgga gaaaggagga gaataggatg tcatttgctg
    20161 cagatgtgaa gaaagaacta actggtttgg aagttcatcg agaacatgcg aaagcggaat
    20221 tagctgcttt gctgcgaatg aacggctctt taggtattgt gaaccagcag tttattttga
    20281 acgtccaaac agaaaatgct gcaattgcca gacgtatcta ttctcttttg aaagatcatt
    20341 atcaggtacg aagtgagcta ctcgttcgta aaaaaatgaa attaaaaaag aacaatgtct
    20401 atatcgtccg gttgaagcaa ggcacaaaag atgtgttgat ggatcttgat atcatggatg
    20461 gtatgatgtt caatggacac gtttcggacg agattatggg aaattcgcaa aaaatgcgtt
    20521 cttacttacg tggtgctttt atggcctcag gttcagtcaa taatccggaa acgagccgtt
    20581 atcatttgga aatattttct atttatgaac agcataacca agacatttgc gatatgttaa
    20641 attattacgg tctacatgct cgaacgcttg aacggcgcaa tggctatatt tcttatttaa
    20701 aaggagcaga aaaaattgct gatttcttaa cattgattgg tgcaaccaac tcaatgctcc
    20761 gatttgaaga tgttcgaatc gtacgggata tgagaaattc ggtcaatcgt ctagtcaatt
    20821 gtgagacagc aaatctgaac aagacgattg atgcggcttc taaacaaatc gaaaacatcg
    20881 aattgatcga agcaaaggtc ggtctacatg cccttcctga aaaacttcag gaaatcgcag
    20941 aacttcggct tcaacatcca gaggtcagct tgaaagaatt aggggaaatg attccctcag
    21001 gtgcgatatc aaaatcggga attaatcacc gaattcgcaa aataaatgaa tttgcggaaa
    21061 aactgcgtga agaagcagtt taatccaaag aaaaaactga tacatgaagc aggagatgcg
    21121 aatgtatcag ttttttttaa aagttatact tgcttttctt ccgtcaaact ataattccat
    21181 ctttactgga gtaacataat ttggaaaggc ttctattgtt tttaatacaa tcgtataaaa
    21241 agcggggaga caactgaatg aagattttag ttttgtacat
//
LOCUS       DAFKHN010000048        21265 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFKHN010000048 DAFKHN010000000
VERSION     DAFKHN010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.048"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            145..1317
                     /locus_tag="LY912_001771"
     CDS             145..1317
                     /locus_tag="LY912_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBM6955450.1"
                     /translation="MSLFDIFKQSIKNEDPSDWIPDFVFGDEESARAYLKIMAKSTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWAMSDVIYMEYNNEELERFTR
                     GLFEDYAELFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDKIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIADVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVAKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            1304..2008
                     /locus_tag="LY912_001772"
     CDS             1304..2008
                     /locus_tag="LY912_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBM6955451.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            2013..3173
                     /locus_tag="LY912_001773"
     CDS             2013..3173
                     /locus_tag="LY912_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBM6955452.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTVEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITGSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVEYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            3249..3527
                     /locus_tag="LY912_001774"
     CDS             3249..3527
                     /locus_tag="LY912_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBM6955453.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            3508..3879
                     /locus_tag="LY912_001775"
     CDS             3508..3879
                     /locus_tag="LY912_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBM6955454.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            3895..4299
                     /locus_tag="LY912_001776"
     CDS             3895..4299
                     /locus_tag="LY912_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955455.1"
                     /translation="MSNVKFEGVQETIQALEKKFGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIDEVVRKNATYRNYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSEPLYFDAVGEEVKKRL"
     gene            4296..4706
                     /locus_tag="LY912_001777"
     CDS             4296..4706
                     /locus_tag="LY912_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955456.1"
                     /translation="MKDMLNIIYEALCLNEYIRSMTYNENTEQYRIKFYEQPETADKT
                     GPMITLRPVDTPNEAYHGSNKELSVEHMVQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFSETKRFVDARRYEGNTKIYDTEY"
     gene            4767..5354
                     /locus_tag="LY912_001778"
     CDS             4767..5354
                     /locus_tag="LY912_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBM6955457.1"
                     /translation="MTLVGFKKMTIGIFDSTGKIPAANLYVIEGEQDKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPTEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFSRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITALKEMVFPAAGE"
     gene            5427..5894
                     /locus_tag="LY912_001779"
     CDS             5427..5894
                     /locus_tag="LY912_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HBM6955458.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            5940..6248
                     /locus_tag="LY912_001780"
     CDS             5940..6248
                     /locus_tag="LY912_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955459.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            6443..13207
                     /locus_tag="LY912_001781"
     CDS             6443..13207
                     /locus_tag="LY912_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBM6955460.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGITGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRDLATKLPASHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKMLKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKALDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDNTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDIVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPNDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPNAKGTNFHPG
                     GAAMVNDQKGPTYEELITLPSGEAFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYADG
                     IGNITTVSSTLNLDALILAINELTTVLRTQLMAETTNAKDTKLSDETKVADPIIPGSL
                     SEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGVAW
                     NKNLLNGWNSLTGTFISTINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYGS
                     FIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMVG
                     GMGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHEE
                     YVQMPDGRGFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDLL
                     DDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDGA
                     VNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRYT
                     AAANYAFEKFPSKIAYVITNGRVRDRMGLSGTGSSGQWTNWPDGDHFDHIHLNGSMGS
                     GDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGND
                     GLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIGK
                     GHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGDDKKRSNTT
                     NTADNSAELVTLIKQQQKQHNELMMILRAILGKDLSLKSSDIGQAANHYMGSDLNKLR
                     YTNGGV"
     gene            13211..14032
                     /locus_tag="LY912_001782"
     CDS             13211..14032
                     /locus_tag="LY912_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HBM6955461.1"
                     /translation="MFYKLQFNQNGKLFDPQRKEKIVCKEIKRQAPVYEVNYEDFEGT
                     NGSREANASFRPFELVLTFDIFYKNKHDKELLLTEFYELIFVGYQYYISYDLSPGKRF
                     KVNPTNFEITEEENDYSTIEITFSIPSGSAESSATTLTDFNLEEEWQFSQGLVAEDYK
                     YTHQTSHFIIYNAGSFEIDPREHYLRIALEGESEGNVTIFNKTTGDRFIYYPSLSTNL
                     GQTLVLDGVIPKLNGVSCGINTNHGLINLVEGVNEIEIQNITRVKSSWDFRFLYK"
     gene            14041..15084
                     /locus_tag="LY912_001783"
     CDS             14041..15084
                     /locus_tag="LY912_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBM6955462.1"
                     /translation="MTELIIRNYEQTKEEILVGYDKGSFYENWQQNETWEIGFTVTSN
                     SLNQEVFDLVEYESSVFYNGQEFVIKEMTRKALGQLLTKQVVATHIYYTVQDGYQYNT
                     VTGAKSISQLLTHVFSAGSRGFTWEVIDPNKKFLTVEQENFGNANYLKLINEILSDYN
                     AVVIPNNKHLTFYPASEYGQQTEEQIRYKYNTDEVSFDIDTYSLKTQIKGYGKLKDGA
                     NTENPKDSDYIFTPITYTSPESQKWGIRIQDPVKDERYTVSGNMLERLKTDLQDYPNI
                     SGSVTLKWKISPNKGDHVPFIYEPLNINTYIQVVGIKTYPAIPNKPPEITLSNTKKTM
                     TSILAEMAKKGVI"
     gene            15084..16115
                     /locus_tag="LY912_001784"
     CDS             15084..16115
                     /locus_tag="LY912_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955463.1"
                     /translation="MGLLKLISNRISTEWKEKFNKNIDYLNDLEKKLSDQDKSMNSRI
                     DNLVLHSGGESPNEVVDARVNNKGETFPTLHGRLVEHETLTDEQISELNTNMDSQKEQ
                     VQQLNKSVQQIIGGYNEPINIYVSKDGSDILGDGSEEKPFLTIQTAVNNVPLITTSQI
                     TIWVGSGAYLEDIMIRNLNFTSFLIRPIDNFDTIDPLKSDLPVKIRSICFTACKGYCQ
                     VAGMQIVDTANGADYGIRNEQSGYMAINRCKFAENTKTLARYNAVYVGGTSKINMYGD
                     TTLINQKVAIYAVLMGEIFVSAFGSGNDVGILCENGTVRGTVSTSFATTPTKTTGYGL
                     IITKGTVLQ"
     gene            16115..18217
                     /locus_tag="LY912_001785"
     CDS             16115..18217
                     /locus_tag="LY912_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBM6955464.1"
                     /translation="MVYKTNESIIMIQAEATSPNRTNVVFWSHDRGTAKLRMKLVRKN
                     GIPQSLPEGTTVPIRLMLKSATAEGGYGKHDYLATIEDRVNGIVSIVLEDNILGYVGI
                     VEGSVYIDFPNDRSLDTAGRFTFDIKRSPIDDSTPELEDYYFNGFSQTIDKIEKILAD
                     GKQEIEQKITESETQIDGKLKETSNKITKANQDVATINTNIDKANDRIDQTNQQISDL
                     GKLKKMYSNSIDFGNYDYSGNPNLMANINADSFSQGSGALSVVDDGDEVVITLDPNHK
                     LEIFKAKSQPALVVGKTYTMSVEIMLEDDFTGDPSNISLRYIKMPSWLTVLYTPYTLT
                     NTKGVWQKLTVTAKMTTAIDNAESWFIMLQNKDANNSLSGKLRLRHAKLEEGSTATPF
                     QPNLLAEPYNMCREYPNENIADPKVKFPIESGDHQIYQGYTEEELMIGQTYTITLKGT
                     KPASQTFVAYNHWTARLGELKPVDGLTDVWSLTFTPTNVVAMPKLFRVYQYPRSTVGA
                     CQIDWLKIEKGNTRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKGLNNAVNVYD
                     PQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKDNSQSFIDGYATFIKHGKEVVVNG
                     TVKFKKAYAFGVPLDDEVPDEFIARIVHGMLTGQSGTNSVSKAMYVQKDLGKIMTNSE
                     FAANEWFTFHGNYWVGVK"
     gene            18218..18664
                     /locus_tag="LY912_001786"
     CDS             18218..18664
                     /locus_tag="LY912_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955465.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGLRADGEPL
                     TIADQMFDPKLNQWIVLANTLDHNDLNNLKAMYEALEHENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPTLKGGE"
     gene            18666..18803
                     /locus_tag="LY912_001787"
     CDS             18666..18803
                     /locus_tag="LY912_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBM6955466.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            18838..19080
                     /locus_tag="LY912_001788"
     CDS             18838..19080
                     /locus_tag="LY912_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBM6955467.1"
                     /translation="MKEEALQDVVERLVRIETKLDNYESLREKADSAKDLADKAYSVA
                     LNNAEDIKEMKNNNKWAWGYMIGLGITIIGYFLTKL"
     gene            19096..19293
                     /locus_tag="LY912_001789"
     CDS             19096..19293
                     /locus_tag="LY912_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBM6955468.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASALVAMLGKAYGWNGTDMIVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            19304..20323
                     /locus_tag="LY912_001790"
     CDS             19304..20323
                     /locus_tag="LY912_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBM6955469.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQIA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            20513..20586
                     /locus_tag="LY912_001791"
     tRNA            20513..20586
                     /locus_tag="LY912_001791"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20547..20549,aa:Ile,seq:cat)
BASE COUNT         7499 a         3447 c         4536 g         5783 t
ORIGIN      
        1 gaaaatagaa agataaatga taacttatta tctcttttga gaataagata cacgttacaa
       61 gatggaaata aaattattat aagtaatgga gtatagtcct agaaataggg ctttttattt
      121 taccttgaaa ggtggtgaaa atatgtgagt ttatttgata tctttaagca atcaataaag
      181 aacgaagatc catcggattg gattcctgac tttgtgtttg gtgatgaaga atctgctaga
      241 gcatatttga aaatcatggc taaaagtaca gttcttgatt ttgttgcaag aactatgtca
      301 acgttagaag ttaagtttaa aaataaagat gggacatcag attgggatta cattctaaat
      361 gtccgaccta attctgatat gtcagcagct acattttggc aaaaattttt ttatcggctc
      421 ttagatgaca acgaagtgtt agtgatattt acagatgata atcaattgct gattgctgat
      481 gattttagtc gaacagagta tgccgtgtat gatgatgttt ttacaaatgt gatggtgaaa
      541 aattttgtct ttgaacgttc atgggccatg tctgacgtca tttatatgga atataataac
      601 gaagaattag aaaggtttac acgaggttta tttgaagatt acgccgagtt gttcggacgg
      661 attctagaag ttgcaatgcg caataaccaa attcgtgggt ctgtctccat tgattcaaca
      721 ggaacggcaa atgatgaaaa aggaaaagat ggtaagacta gatctcaaag attacaagaa
      781 tatattgata agatttggaa ctcttttaaa actaactcag ttgcaattgt tcccaaagtg
      841 aaaggctttg agtatgagga atacaccaat aaacaaggcg tatcgaatca atcactagat
      901 gaactgaata agatgaagtc gtctttaatt gccgatgttg ccaacgccat aggagtacct
      961 acggcgctta tttatggcga aaaagctgaa ctagattcaa atattaaagc ttttcgtaaa
     1021 ttgtgtattg ctccactagt taaaaaactt caggacgaat tggtggcaaa aataattagt
     1081 cgacaagagt acaaaaacgg ggaacgtata gaagttaaaa aagttctcca aaaagatcta
     1141 ttagagtatg ctactcaaat tgacaaaata acatctggtg gtgcgtttta tattgacgaa
     1201 gttcgtgatg aagttgatta tgatgagttg ccaaataatg aaggaaaaat tcgtattcgt
     1261 acgaaaaact atgaagaaac tgtgaaggga ggtgagaacg acaatgccga aagctaaaaa
     1321 agtaccattt cagtttacta acgaaattca gaatggtaag cacattctca ccttgagtgg
     1381 aaatgtacag aaaaaatatt ggcgtgatga tgatgtcata aacgctaaag atattcgtga
     1441 ctctctagat actgtaaccg atgatattgt aatcaagttg aacagcccag gcggtgatgt
     1501 gtttgaaggg attgagattt acaattattt aaaagatcac ccatcaaata ttactgtaga
     1561 agttacaggg cttgccgcaa gcgcagcaac gtttattgtc gctggtgcca atgatgtgat
     1621 tatgaatgtt gggacttctt tgatgattca tgaagcttct acatttgctt gggggaataa
     1681 acaggacatc caaaaaacgt taaacgcatt ggaaacgatc gatgattcta tcttagctat
     1741 ttattcagat aagactggcc aatctgttga taagttgcgt gaatggatga atgaagaaaa
     1801 atggtttaca gcagatgaag ctgtcaaata tggatttgcc aattctgtga agcgtgaaga
     1861 accacaaaac gaacctcaaa atattgcagc gatgattcaa gatgctgttg ccgttgcaat
     1921 agcgaattta aaggaacctg ttactaataa aatcgaacaa gaatcaaaac aaaaatcatt
     1981 aatcgcacga ttgcgaaaag gagaataaag atatgttaaa aattacagat aaaactgcag
     2041 atgcaaaaaa ggcatttaat gctatttctt cgaaagaaga tgcaacaccc gaacaaatta
     2101 atgctgctct agaagaatat gtaactgcca ttgcagaaga tgccggcaaa caggtgcgtg
     2161 ctgaatatga agaattgaaa aatgtgacgg acaaccgtgt attagaggct cgtggaattc
     2221 ctacactaac agtagaagaa acaaagtttt ataatgaagc cgtaaaatct ggaggtttcg
     2281 attctgacgt agtttggcca gaaacgattt tggaacgtgt ttttgaaaat cttcaaaacg
     2341 atcatcctat tttaggcctc attaacttta caccaactgt aggtcgtgtc aaagtaatta
     2401 gagcacgtcg taaaggtgtt gctgtttttg gaccattgca taaagacctt gaaggccaac
     2461 tagatgctga atttggtgca actgaatttg ttcaacttgc gttgaccgca tttttcttaa
     2521 tttctaatga taccttagat ttaggaccac gatggattga ccgttttatc aatctttctt
     2581 taagtgaagc agtacgtgat gtttgggcta aaaaaattat tacaggttct ggtaaagatg
     2641 agccaattgg attgcttaaa gatctagatg gtgcggtcac aagtggtgta tatccagata
     2701 aagctagcgc agggacatta acttttgcga aagagaagat tgttcttgaa cttgcagggg
     2761 tgatgaaaaa attatctaaa tacacataca aagtagatgg tgacgatgaa ggtgaagtgg
     2821 aataccgttc tgttgctgga cgagtgtatc taattgttaa tcctgttgat tactgggata
     2881 tcgtagctag agttacattt gcaaatttaa acaatgtgta tgggactacg atgccattta
     2941 tcgctgttga tcatatcatc gaatctgtag acgtaccaga aagtaaatgc attgcatacg
     3001 ttgataaaga gtatgaagct actcaatcaa gagctgaaaa agtctatgta tataaagaaa
     3061 cttttgcaat gaaacgcgca actttgtatg ctgtcgacat gcttggtaat ggctatccaa
     3121 caaataatga tgcagcacaa gtatatgact tggactttac agcgggggag taacgtcccc
     3181 tgcaattggt gagataacac cgacgactga tggggcagtc attaatcttt cgtaaatggg
     3241 gttagagtat gaacactgaa gaatttataa aagaatataa ggcccgattt cgtattttcc
     3301 atacttccga agatgaggat atcgggaaac agttagagag cgggtttgcc gatataaaat
     3361 ctctaatcgg cagttttgat ccttccactt atgagaaagg aaaagaatta gtttatgaac
     3421 gtactcggta tctacggaac gaatcactag agtactttta cgacaatttt caaacaatga
     3481 ttatggatgc atcaattgat ctggcaggtg ctggatatgc caattaaatc aaattataag
     3541 aagcctaaaa ttgtagctgg tgatctaaat acgccagtta ctttttttga gtttcaacct
     3601 aataagggtc cagaacctgg tgatgaagaa aaaaaggaac tgtatttttg tacagcacta
     3661 gtttacaacc catcaatgaa agatcgtgac attcttggca caaaagaagg cgttacgata
     3721 aaaatacggg atccccatca atcttatatt cctactaaca aacataaagt aaggatatta
     3781 gattatcgat atggagataa agtttgggaa ataatcgatg tctcaccgga tttggaagaa
     3841 aattcaattg taaagatagt attagaatta attacttaaa tttggtgata aacgatgagt
     3901 aacgtaaagt ttgaaggcgt tcaagaaaca atccaagctt tagaaaaaaa gtttggagaa
     3961 aagaaaacta agacattaac aaaaaaagca atcaatgttg gcgctgaaaa agtagaaaaa
     4021 cagttgcaaa cggacatgac cgtttttaaa gacaaaggtt atacgattga tgaggttgta
     4081 cgtaagaacg ctacgtatag aaattacaag gcagaagctg aaatcggttg gaatggtcct
     4141 catcagcgtt atagaatcat tcacttaaat gaatggggat atacacgaaa aggtaagcaa
     4201 attaggccaa gaggttttgg cgtaatcact aaatcgctta aaaattccga gccactatat
     4261 tttgatgctg ttggggagga ggttaaaaag agattatgaa agatatgctc aatatcattt
     4321 atgaggctct ttgtttgaat gagtatattc gttcaatgac atataacgag aataccgagc
     4381 aatatcgtat taaattttat gagcaacctg aaaccgccga taaaacaggg ccaatgatca
     4441 cacttcgtcc tgtagataca cctaacgaag catatcacgg aagtaacaaa gagctttctg
     4501 tagagcatat ggtacagatt gatgttgaat cgaaatatag agcaacatgc aagcagattc
     4561 aatatgagat aaaaaaagag atgaaaaaac taggctttgg ccaaatttct ggtcaagggt
     4621 tagatgaata cttttctgaa acaaaacgct ttgtagacgc gcgtcgttac gaaggaaata
     4681 caaaaattta cgataccgaa tattagaaat taagacacga aaataacgtg tcttttttta
     4741 ttacccaaaa ttaggaggaa aattttatga ctttagtagg attcaaaaaa atgacaatcg
     4801 ggatctttga cagcacaggg aagattccag cagcaaattt atatgtaatt gaaggtgaac
     4861 aagacaaagg ggcgactgta tctgctgaaa tcagtgggct atcaaaagaa ccatcaaaag
     4921 tttacggatc gaacatcgct tactatgtct ctcaaaaagg aacaggcgat gtttcagcta
     4981 cttttggatt gttagattta ccaacagaag taaatgacaa aattcttggt tacaaaaccg
     5041 atacaaacaa aatcagcttc ttgggagaag atactgagcc accatattgt gcaattttga
     5101 tggaatcgga ggatttgaac ggcgatacag caatgcttgc gatgttcaaa ggaaaattca
     5161 gtcgtgaatc tattaatctt aacactacga caaatgaagc tttcgaacca gaagcagaag
     5221 aatatgtatt ttcagcgatt gccaatgatg ttgaaggtga tgctaaaggc caaacagtcg
     5281 caaaatatgt tggagacgaa gaagcttcta ttactgcttt gaaagagatg gtatttcctg
     5341 cagcggggga gtaactagct ccgttgttgg agcaatcact cccactatta atggggtaac
     5401 agttgaatta agttaggagg ataactatgc cagatacatt taaaatctat aaaaaaaatg
     5461 gtactgaatt tacaaaagtc gcagagggtg aaagtccact ttctattact ggaattgcag
     5521 caaatactca agttgctaaa ggagactacc aagctacgcg tgtggttgga ggtcaagaat
     5581 cagtaaaagt agatattcct gcatttacca ctcttccaat ttcagttact ggtgtgacgt
     5641 tggataaaac gacagctgaa gtcgaacaag gcggaacctt aaaattaact cctactgtaa
     5701 caccagcaaa tgcaacagac aaaacaggaa gctggagcag ttcgaataca gctgtagcta
     5761 ctgttactgg aggcaacgtt acagtaaaaa cagacgctga agttggcgga actacagaag
     5821 tttcatttac tactacggat ggcggtaaag tagcaaaatg tactattaca gttattgaaa
     5881 aagcagcggg ctagtcttcg gactagcttt tttatttgga aaataatgga ggaatctaaa
     5941 tggcaaaagt aagaattgaa ttgaaagaag aatcaggaaa gaaagtctat gaaaacatag
     6001 acacaacagg taaagattat cgaaaagctt tagaaacaat caaaaagcta aatgaagatg
     6061 gagtaatgat ttggaatcgt ttagacattt atttggattt tgctgtaggt atcttcaggg
     6121 atagcaaatt gacagctgaa caaattcttg atggcttacc atctgagaag gtaatgagca
     6181 cattggacga catcctagga gaagtaatgg ggattgaaag taatccagac ccagacgcaa
     6241 aaaagtaaca cccgaagaag cagaagaaat gtacttaaac ctatgcagag agttagtgaa
     6301 agcgggatgg tcactatctg acatagaaga taattccttt gaaatgatga tgaaaattgc
     6361 gtgcacttcg cctaagaaag agaaacaaaa agaagttgat cttaaagact tcttgaaatc
     6421 catgtagaga ggaggtaaac atatggcaaa tggaaaacct ttaggcaata tgattataaa
     6481 actagactta gacagttcag ctttttcaaa aggtctagcc ggagctaaaa acgctgttaa
     6541 ccatcaaatg aaagcaatga aatcacagat gcaagtaatg aactcttcag ggaattctct
     6601 cggtgcttta caagcaaaat ataatggttt aggcggagtt ctacaagcaa atgaaaagca
     6661 agtagaattg ctcactaagg cttataagga tagttttgac tctaatggaa acgctactgc
     6721 ttcgactgct aaatacgcta atcaattgaa tcaagcaaca gctagatcag caagttacga
     6781 atctcagatg aaaacaaccg ttggacagat tgctcggatg aaagtggaaa cggaagggat
     6841 tacggggaaa ctaaaagcta attctgatgt attgattaat tctgggaaaa aaattgaagc
     6901 ctttggtaaa ggagtttctg ggataggatc tgccctaact gttggagtaa cagctccaat
     6961 agtggcaggt gcaactgctg ttactagtgc agctatttct tgggaaagtg cttttgcagg
     7021 agtaaaaaag acaaatgatg aagttgtaga ttcgaatggg aacgtagttt actcctacag
     7081 tgatttagaa aaaggccttc gtgatttagc gactaaattg ccagcaagcc accaagaaat
     7141 agcgaacgtt gctgaagcag caggtcaatt agggattaag acagaaaatg tagttagttt
     7201 caccaagaca atgattgata tgggcgaatc tactaatatg tcagcagaaa cagctgcaac
     7261 ttctttagca cgatttgcta atataaccca aatgtctcaa aaagactttg ataaattagg
     7321 atcagtcatt gttgatctag gtaacaattt tgctacaacc gaatcggaaa tcactgaaat
     7381 gggactgcgg ttagcgggtg ctggtaaaca gattggaatg agccaaggcg aaattctagg
     7441 atttgctact gctctatcct ctgttggtgt cgaagctgaa gcaggtgggt ctgccttttc
     7501 gaaggtcatg atccagatgc aactagctgt agaaaaagga tttggcgctt ttgatcagct
     7561 gaaacagatg gcagaagaac aaggtgttcc gtgggttaat ttagtaaatg ctgtgagaga
     7621 cggtggaaaa tcgttaaaag cagtatcaga gcaaatggga ttcacttcat ctgatttaaa
     7681 gaaaatgtat aaagaagcgg acaattcgaa aagttcgctt gaaaattttg cgaatgtggc
     7741 aggtgttaca agtgaacaat tccagaagtt gttcaagagt gatccttcag aagcaatcat
     7801 caagttcatt caaggactga aagattcaga aaaacatggg acttcagcaa tcaaagttct
     7861 ggatgacatg gatataaaag aagttcgact acgcgacagt ttattgagag ctgcaaatgc
     7921 tagtgacata ttcaaaggag caattgaaaa aggaaacggc gcgtggaaac aaaatacagc
     7981 tttaacaaat gaagctaata aaagatacga aacaactgaa tcaaagctaa agatgttgaa
     8041 aaacgaagtg attgatacag caatcgatct tggaggtcca tttgtagacg cgttgcgtga
     8101 tggtctaaat gtatcaaaac cgttgataaa aaacttaggg aatatggcga aagctttctc
     8161 agccatgagt gatgatcaac aaagaaacat tatcaaatgg gttggattag cagcagcagc
     8221 tggtccagcg ctgaagcttt taggaactgg tacttcagta ataggtaaag ttacttcaac
     8281 tactggaaga ttgacgaaaa gccttgttga tttagcagcg aaagcagcag aaaagaaggc
     8341 tctggatgcc tttgcatcgt cggtaacaac agctggtgct gcagctgcaa agacagcagg
     8401 agctggaggt attggcgggt tagtccctat gatgggaaaa acagctagtg ctgcaagtac
     8461 tgctgcgggc gctagcggaa taggcgcaat gacaacatca ctaggtttgt taggtcctgc
     8521 tctacttggt attgttggcg ttggtggcgc actagcagtt ggctatggag catggaaatt
     8581 atttggtgaa gaagcttgga attcctcgca aagagtaaag caatggggaa cagatgtcgg
     8641 tgaggaaata gataatactc ttgacggagt acagaagaat attgaaggtg caaatggtca
     8701 attcggtctt ctcaaagagg gttttactgt tgatgatgcg aataatatgg cggctaattt
     8761 cgcaaccgct ggaacatctt tggaaacatc tttaacaggt agaataaagg cattagacga
     8821 tgcactaaaa gggctacctc aatcagttca ggatgccatg aaagaagtag ctgaatcaga
     8881 agaagaaacc ttagggcaat ctctttctaa aataaaagac aacaatgaag aaataaaaaa
     8941 aatcagagaa agagccgcaa atcagaacag agacttgact gtttcagaac tacaacagat
     9001 acaggatctg atgaaaggaa cttctcaagc gtatgtggat acgctcgatg tttctgctaa
     9061 agacagaaaa aagatactat cagccatgaa tggtgatgtt gcacaggcta cagaagaaga
     9121 agcgaagacg tggttacaat ctttagcgaa acaaaaagct gcaactaccg aaaattatag
     9181 acaaatgctt gaagaaaaaa aggcggcttt aaaggaaaag ggagtaagca aagaattcat
     9241 tgatgcatta gaagatgaaa tgaatgatta catcaaaact acaaatcaag gattcgatag
     9301 ccaaatagct gctataacaa ataaatatcc acaattgatt aacgaagtga gtttatcaaa
     9361 tggtcaatta tttagcaaaa cggcagctgc tatggacaat actggtcagt atacaaaagt
     9421 ttttctcgaa agtaatgaaa agattttagc ccaagcgaag aaaacatcgg atgaaatagc
     9481 agataatgcc gaaaaaaatg cagaacaact tggtatggta gctgatgagg ctacgcatgc
     9541 tggatcaact tggaatggat tagttttaga cgaaaaaaca ggaaaagtaa aaactaacgt
     9601 acaagaagta gtgaatgaag caacgaagga tttcactaaa tggaatgaac ttaaacctgt
     9661 tgttcatgat gcgaaactaa caacgaacgc aaaagatgtc atttccatag cggcagtaca
     9721 aaatggttat tgggatgata tggaatggaa agaaaaagaa gcattattag aagatgagtg
     9781 ttctaaaaat gtatacaagg ctttagaaaa tgctggtaaa tggaatgagt tagatattcc
     9841 ttctaaagaa gcaatcctaa cttcaaatac tcctgaagtt atgggtgaaa ctctcatgaa
     9901 tttgggacta tgggatactt acaaacttca agtgaaagat ttagatttga atgcgtataa
     9961 agtatacgat gctatcgatg gatcagaaga aaaattaaat agttgggctc aattagataa
    10021 ccccacaaaa gaattgttat tagataactc agatttttct acaaaacttt ttaattccga
    10081 agaaatgttt aaacgttgga atcagttatc atctaatgca aagtttcttt cagctaataa
    10141 tactaaattt acagaggttc ttttatcatc tgacagaatg tggaatcaat gggtaaacct
    10201 tcctgataat gagaaaagat tacttgcaga taacgaagat ttagctacca ctgttttatc
    10261 ttcagaagaa atatacggaa gatggactca attaccagat aatcaaaaat atatgttagc
    10321 tgacaatact gacttagcaa acaaaatatt tgcttcagaa gaatcatgga atgcatggaa
    10381 agcaattcca gacatagtta aaaacttgct tggtaataat attgatttac tggctaaagt
    10441 gaaagatggg actgtaagtg tagaagaata taacaaagtt atgccacttc ttaaaactct
    10501 atatggagat aacgttaatt taaaagaggc aatcagtggg gctaaaagct ctatagagaa
    10561 ttacaacaaa aatatttttc ctaatgataa aactgcagta ggacacgatg aggcttcaca
    10621 agctgctaaa gatgcatttg aagcgttcaa catcttccaa acaaaaatac cagataaaat
    10681 tactaaaact gtatcagctg actttatagg tcctatgcct aatgctaaag gaacgaactt
    10741 ccatcctggc ggagcagcta tggtaaacga tcaaaaagga cctacttatg aagagcttat
    10801 aaccttgcca agcggagaag cttttatacc taaaggacgt aatgtcgttt tagacttacc
    10861 aagaggttcg aaagtactga acgccactaa aactaaacgt ctagtaccta aatatgctga
    10921 tggtatagga aacataacga cggtttcatc tacgctaaac ttagatgctt taattttagc
    10981 tattaacgag ctaacgacgg tattgagaac tcaactgatg gcagaaacga ctaatgctaa
    11041 agatactaaa ctatcagatg aaacaaaagt tgccgatccg attattccgg gcagtctttc
    11101 agaaaaatca gatcagtatc taggaattgg agctcaatgg ttaaccaatc taatgaatgg
    11161 ttggaactca gcggttcctc aatatatgaa tagtgaaatg gtttttatta caaactatct
    11221 caatgcgcta aaacttcaaa acaatcctaa ttatacgcaa ggagtagcat ggaataagaa
    11281 cttactgaat ggatggaata gtttaactgg gacatttatt tctacgatca attcattttg
    11341 taatcaagca atggtcacgc ttagaaacta caacactcct atgtacaaca atggccgaac
    11401 gtggcagcaa aataatctta atggttggaa ttcattgtat ggatcattca tagcccgtgt
    11461 aaatcagctt ggtaacgatt cgattaacaa ccttcgttct aaaagtggtg gtttttacaa
    11521 tgcagggaca ttcttgttgc aatctttaat aaacggaatg aattcgttag gtaattctct
    11581 ttctacaaca atgaacaatg tcgctaatac aatggttggt ggtatgggca aaggggttaa
    11641 tggcgtcata tcgggagtta actatgtgct taaggaagtc gagtcaagta agaatatcgg
    11701 aaactggcca attccacaat acgctaaggg aactgatgga catcctggtg gacttgctat
    11761 gattaatgat caaaaaggcc tagttcacga agaatatgta cagatgccag atggacgtgg
    11821 ttttattgcc aaaggtagag accttcttgt taatttgcct aaaggtgctc aggtcttaaa
    11881 tgcttcttta acaaagaaat taaaggaacg tttaaatatt ccacactacg aaaaaggtat
    11941 tggcaattta gatattgttg atttgttaga tgatgaaaaa agaatgttag aattcttgac
    12001 tagcaaagtt gacttttcag gcattaatga accatggctt gatatgacta aatcaggaac
    12061 gtcattaatg tctaaagctg caaatacaat gcttcaatca aaattaagtg aattcttcac
    12121 tcatggcaat tttgatggtg cagtaaatgc caatggtgtt tatcaatatt tagttgatgt
    12181 tgcacagaaa gtaatgggta agttccccgg acttacagta acttctggat atcgagcagg
    12241 agatgcttac tatcacggaa aacggcaagc tatagacttg gcttatccag gtatatctgg
    12301 agatccgaga tatacagcag cagctaatta cgcttttgaa aaattccctt caaaaattgc
    12361 gtatgtcatt acgaatggac gtgtacgtga ccgcatggga ttatctggaa cagggtcaag
    12421 cggacaatgg acgaattggc cagatggcga tcacttcgat catattcatt taaacggttc
    12481 gatggggtct ggcgatatat tcaatggagg agttggagga agtggtgttg cacgctggcg
    12541 ttcttatgtg tctaaagcat tgaaaatgaa tggattacca gctacagcag cttatataaa
    12601 tgcctggatg tcccaaatcc aaacggaatc tggtggtaat gagaaagcaa tcggcggcaa
    12661 tgatgggctc gctgaaggca atgcaacagg attacttcaa acgaaacccg gaacttttgc
    12721 agctaacgct tttcctggtc acggaaatat tatgaacgga tttgataaca tgttagcagc
    12781 aatcaattat gctaagaaac gttacggagt tgcaggtatg ttgcaagtta tcgggaaagg
    12841 acatggatat gccaatggtg gattgattac caaagacgga ctatatcgag cgggagaagg
    12901 aaataaacca gaaatggtta ttccattgac aagaaaaaca agagctattg aattgatggg
    12961 tcaagcatta gcttttcttt ctggcgatga caagaaacgc tccaacacta caaatacagc
    13021 tgataattca gcagagcttg taactttgat taaacagcaa caaaaacagc ataatgagtt
    13081 aatgatgatt cttagagcga ttcttggaaa agatttaagt ctcaagtctt ctgacattgg
    13141 gcaagctgct aatcattata tgggctctga tttgaataaa cttcgatata cgaatggagg
    13201 tgtttgataa ttgttttaca aattacagtt caatcaaaat gggaagttgt ttgatccgca
    13261 aagaaaagaa aaaattgtat gtaaagaaat caaacgtcaa gcaccagtgt atgaagtgaa
    13321 ttacgaagat tttgaaggga cgaacggtag cagagaagct aatgctagtt ttcgtccttt
    13381 tgaattagtg ctgacttttg atatctttta caaaaataag catgataaag aactgctatt
    13441 aacagagttc tatgagctaa tttttgtcgg ttatcaatat tacatttcct atgatttaag
    13501 cccaggaaaa agatttaaag taaatccaac aaatttcgaa attactgagg aagagaacga
    13561 ttattctacg atagaaataa cctttagtat tccatcaggg agtgctgaat ccagcgcaac
    13621 cactttaacg gatttcaatc tagaggaaga atggcaattc tcgcaaggtc tagtggcgga
    13681 agattacaag tatacgcatc agactagtca cttcattatt tacaatgctg gaagctttga
    13741 aattgatcca cgtgaacatt atctacggat cgcattagaa ggagaatcag aaggaaatgt
    13801 gacgattttc aataaaacaa ctggcgatcg atttatttac tatccatcac tttctacgaa
    13861 tctcggacag acattagtct tggatggcgt gattccaaaa ttgaacggtg taagttgtgg
    13921 aatcaatacg aatcacggtc tgatcaattt ggttgaggga gtcaatgaaa tcgagatcca
    13981 aaatattact cgcgtgaaat cttcatggga tttccgtttc ttatataagt aggtgattga
    14041 gtgactgagt taattattcg aaattatgaa caaaccaaag aagaaatcct tgtcggttat
    14101 gacaagggtt ctttttatga aaactggcaa caaaatgaaa cgtgggagat tggctttacc
    14161 gttaccagca attcgttgaa tcaagaagta tttgatttag tcgaatacga gtcttctgtt
    14221 ttctacaacg gacaggaatt tgtgatcaaa gaaatgactc gcaaagcact tggacaattg
    14281 ctgacgaaac aagtagttgc gacacatatc tattacaccg ttcaagatgg ttatcagtac
    14341 aacacagtga caggtgcgaa atctattagc cagttactca cgcatgtatt tagtgcaggg
    14401 agtcgcggct ttacatggga agtcattgat ccaaacaaaa aattccttac cgttgaacaa
    14461 gaaaatttcg gtaacgcgaa ttacttgaag ctgatcaatg agattctatc tgactataat
    14521 gcagtcgtga ttccgaataa taaacatcta actttctatc ctgccagtga gtacggccag
    14581 cagacggaag aacagattcg ctataaatac aatacagatg aagtgtcgtt tgatattgat
    14641 acgtattcct tgaagacgca gatcaaaggc tatggaaaat tgaaggatgg tgcaaatact
    14701 gagaatccta aagatagtga ctatatattt actcccatca cttatacaag ccctgaatca
    14761 cagaagtggg gaatcaggat acaagatcct gttaaagacg aacggtatac cgtatcaggg
    14821 aacatgctcg agcggttaaa gacagacttg caagactatc caaatatttc gggatccgta
    14881 accttgaaat ggaaaatcag tcccaacaaa ggcgatcacg tcccattcat ttatgaacct
    14941 ttgaatatta atacgtacat tcaagtggta ggaatcaaga cgtatccagc gataccaaat
    15001 aagccaccag aaatcacatt gagcaacaca aagaaaacaa tgacgtcgat actcgctgaa
    15061 atggcgaaga aaggagtgat ttgatggggt tattaaaatt aatcagtaac cgtatctcta
    15121 cggaatggaa agagaaattt aataaaaaca ttgactacct taatgatctt gaaaagaaac
    15181 tgtctgatca agacaaatca atgaacagtc gtattgataa tctcgtgctt cattcaggtg
    15241 gcgaatcgcc gaatgaagtg gttgatgctc gtgtaaataa taagggagaa acctttccta
    15301 ctttacacgg cagattggta gaacacgaaa ccctgacaga tgaacaaatt agcgaactga
    15361 atacaaacat ggatagtcaa aaagagcaag ttcaacaatt gaacaagtct gttcaacaaa
    15421 ttattggtgg atacaatgag ccaattaaca tctatgtttc taaagatggt agtgatattt
    15481 tgggtgatgg atcagaagaa aagcccttct taaccattca aacagccgta aataatgttc
    15541 ctctaattac aacgtctcaa attactattt gggtaggtag tggggcttac ttagaagata
    15601 ttatgattag aaatttaaat tttacatcat ttttaattcg acctatcgat aattttgaca
    15661 ctattgatcc attaaaatca gatttacctg ttaaaatacg atccatttgt ttcactgctt
    15721 gcaaaggtta ttgtcaagtt gctggaatgc aaattgtgga tacagcaaac ggagcagact
    15781 atggaatcag aaatgagcaa agtggctata tggcaatcaa tagatgtaaa ttcgcagaga
    15841 acacaaaaac acttgcaaga tataatgcag tttatgtcgg cggaacatca aagattaata
    15901 tgtacggaga cacgacgttg attaaccaga aagtggcaat ttacgctgta ttgatgggtg
    15961 aaatttttgt cagtgcgttt ggttcaggaa acgacgtagg aattttgtgc gagaatggca
    16021 ctgtacgagg aactgtatca acttcttttg ccacaacccc aacaaaaact actgggtacg
    16081 gtctcatcat cacgaaaggc acggtgttgc aataatggta tacaaaacaa atgaatcgat
    16141 catcatgatt caagcagaag ccactagtcc aaacaggacg aatgttgttt tttggtcgca
    16201 tgatcgagga acagctaagc ttcgaatgaa attagttcgg aaaaacggca ttcctcaaag
    16261 cttacccgaa ggcacaactg ttccgattcg cttgatgctc aaatctgcaa cggcagaagg
    16321 tggttatgga aaacatgact atctcgccac cattgaagat cgtgtaaatg gtattgtgtc
    16381 cattgtgctg gaagataata ttttaggcta tgttggaatt gtcgaaggta gtgtttatat
    16441 tgatttccca aacgaccgct cgttagatac agctggccgt tttacttttg acatcaaacg
    16501 cagtccaatc gatgatagta caccagaatt ggaagattat tatttcaatg gtttcagtca
    16561 gactattgat aaaatcgaaa aaattctagc tgatggaaag caagagattg aacagaaaat
    16621 tacggaatct gaaacgcaga ttgatgggaa actgaaagaa acaagcaaca aaatcacgaa
    16681 agccaatcaa gatgtcgcaa ctatcaatac gaatattgat aaagcaaatg atcgtattga
    16741 tcaaacgaac cagcaaataa gtgatctcgg aaagctgaaa aagatgtact ccaacagcat
    16801 cgatttcggg aactatgatt atagtggaaa tccgaatttg atggctaata taaacgctga
    16861 tagcttctcg caaggtagtg gtgccttatc tgttgtagat gatggtgacg aggtagtgat
    16921 tacgcttgat ccaaaccata aattagaaat attcaaagcg aaaagtcaac cagctctggt
    16981 agtggggaaa acatatacca tgagtgtaga aattatgtta gaagatgatt tcactggaga
    17041 ccctagtaat atatctctaa gatatattaa aatgcccagc tggttaacag tactatatac
    17101 gccttataca ttaactaata ctaagggtgt atggcaaaaa ctaactgtta ccgctaaaat
    17161 gactactgcg attgataacg ctgaaagctg gtttataatg ctacaaaata aagacgctaa
    17221 taacagccta tccggcaaac tacgtttgag acacgctaaa ctcgaagaag gctcaacagc
    17281 tacaccattc caacctaact tattagcaga accttacaac atgtgtcgcg aatatcctaa
    17341 cgaaaatatt gccgatccta aagttaagtt cccaatcgaa tctggcgacc accaaatata
    17401 tcaaggctac acagaagaag agcttatgat aggtcaaacg tatactatca cgcttaaagg
    17461 aacaaaaccc gcaagtcaaa cctttgtagc gtataatcat tggactgctc gtttaggaga
    17521 actaaagccg gttgatgggt tgacagacgt atggtctcta acattcacac caacgaatgt
    17581 tgtggcgatg cctaaacttt tccgtgttta tcagtatcca cgatcaacag taggcgcatg
    17641 ccaaattgac tggctcaaga ttgaaaaagg caacacccga acgcccaata ttagtcagtt
    17701 taaatacttc ggtgaaggat tgaaagacag caacaatccg aatgattaca gttgggatgt
    17761 cacacctgaa tatactgaaa aaggcttgaa taatgctgtt aatgtgtatg atcctcagag
    17821 agttgaaggt ttgaaaaact ttgccgatgg tattcaaata gcaggagata aagtgatcag
    17881 tgaaaatgat tgcactgttt atacattaac taaagacaac agtcaatcgt ttatcgatgg
    17941 gtatgcaaca tttattaaac acggaaaaga agttgttgta aatggtacag taaagttcaa
    18001 aaaagcttat gcttttggtg taccacttga tgatgaagtc ccagatgaat ttattgcaag
    18061 aattgttcat ggcatgctta caggtcagtc aggaacaaat agtgtatcaa aagcgatgta
    18121 cgtgcaaaaa gacttaggaa aaattatgac gaatagcgaa tttgccgcaa atgaatggtt
    18181 tacattccac ggtaattatt gggtaggagt gaaataaatg aaaaacattt ggaaatacgg
    18241 acgtactggt ggagagtacg caggaaaagt attggacgac atgcttgtat ccgttcctta
    18301 cacggatcag ccaccgctcg aaggattacg tgctgatggc gaaccgctaa cgattgctga
    18361 tcagatgttt gatcctaaac tgaaccaatg gattgtttta gcgaacacac tggatcacaa
    18421 cgatttaaac aatctcaaag cgatgtacga ggcactggaa cacgagaacg gcgatttaaa
    18481 acagctcaac gccaaactca tgctaagcga tgtagcaatt aaacaggaaa atactgcatt
    18541 gaaagaaaaa gcggatagtt tagcacaaat caattcaaaa atgatgcttg cttcgttaca
    18601 aaatagcaaa gacatttcag aaattaaaga gcaactaaat ccaactttaa agggaggtga
    18661 gtagtatgtt tagttttagc gatgtgaaaa tgatgtatga ttggggctgt tttactgacg
    18721 atcaagttcg actattcgtt ccactatgca ttacagacga agaagcagat aaaatcatta
    18781 gcaaagaaga gagcgcatct taagtgatgc gtttttttgt tggaaagttg gtggaacatg
    18841 aaagaagaag cgctccaaga cgttgtggag agattagtaa gaattgaaac aaaattagac
    18901 aactacgaat cacttagaga aaaggctgat agtgcaaaag atttagcaga taaagcctat
    18961 tcagtagcac taaacaatgc agaagacatc aaggaaatga agaacaataa taaatgggct
    19021 tggggctata tgattggctt aggcattacg atcattggct atttcttgac taaattgtaa
    19081 aggaggtgag aagaaatgat tttaccagat aagtattatc aagtcattaa atggacagtt
    19141 ttaacagtat tgccagctgc atctgcttta gtagccatgt tagggaaagc gtatggatgg
    19201 aatggaacag atatgatagt gttgactatc aatgcagtag caacattttt aggcgttatc
    19261 actggtgtgt cggcttataa tttgaaaaaa taggaggaaa caaatgaaaa agaaaattac
    19321 tattactgcg atgagcctat taacggctct ttttttattg ccaattaatg ggtttgccta
    19381 tactatcaac aatgaattta atttgggcgc aaatgaaggt agctcacaaa tagcaaataa
    19441 tcagtacatt ttactgcatg aaacggctaa tgaaacagca acaggacgca atgaagcgca
    19501 gtatatgcaa cgttcatgga ctagcgctta tactgcttat attgtgggag acggcggaat
    19561 tgtttatcaa gtcggtcaac ctggttatgt acagtacggt gctggttcgt atgctaatgc
    19621 caacagtcct gtgcagattg agttacaaca cacacatgat aaagcaacgt ttgagaaaaa
    19681 ctacaaggca tacgttgaat tggctagaga ttcagcaatg aaatatggta ttccattaac
    19741 attagacacg ccttataacc aaccaggaat caaatcacat ttatgggtaa cacaaaatat
    19801 ctggggagat catactgatc catacggtta tctttctgaa atgggcgtaa gtaaagaaaa
    19861 attagcatat gatttagctc atggatttac cgatgaaaat ccaacaactt ctgaaaacaa
    19921 gcctgtcatt gatccaacac gagctggtgc agctaatcct acgctgacag atggaacaaa
    19981 tcacgcccac attgatcagt ttggggaaat cgaaaacgca aacttgcatg tggctggatg
    20041 gcacattgct aactataaat acgagtatat tttcattatg gactacaata ctgggaaaga
    20101 attagctcga gtaagagctg atggaattta tagaccagat gtaaaccaag cttataatac
    20161 ttctggaaat gttggttatc atgtatcttt caatatgcgt aattttccta gtaagaaagt
    20221 ctatgtaatg atgcgggcaa cgaatgatcc agagggaaac actaaaggcg gtgcgcaaga
    20281 tttccatgac aaacgttggt atttaaatat tcctaaacga taaaaatagc tcctcgttga
    20341 ggagcagtac ataactatat tgacaactat aaaaattatt cgataaaata gtgatgttat
    20401 cgcatatctt cactatcacc cataaatagt cacactccaa gctatgcgat aacaggtttg
    20461 ttgccacaca ttctactggt tgattgttta tggctttatg tggcaacaac cagtaccctt
    20521 agctcagttg gtcagagcag acggctcata accgtccggt cgtaggttcg agtcctacag
    20581 ggtacattaa cgtagccatt tgaatcgttc tgtgttagaa tttttttgaa gagtattata
    20641 caagctaaag cttttcttca ttgccactca aatgagtggc ttttttatgt atccttttat
    20701 ggattaatga aaggatgttt cacatagtta tacttctgta tatttgaaaa gttttacttt
    20761 gatttttaaa tagaaagaca tttgggttaa attgtgagat aataataaag aagagtttaa
    20821 agcgcacccc aaaccacttc cccataagtg tgttacgctt taaactcttt tatatttgaa
    20881 gccattaaaa agcataccat atttttgaaa aaaagtgaga aaaaaggctt acaattggag
    20941 tggtagttaa ttagtgactt atttttgatt ttatagcact gatactataa aatatagata
    21001 tcatcatatt acacaatctt aatactaact taaaaaatat ctcctttcac aagtatggtg
    21061 ataaaattcg ttccgggcta cctttttagg tagcctactt taatctttat acctttctgg
    21121 atcaacgaaa gtatacttta tatagtcata acgccgatga tcgctacgtg cgtccggcac
    21181 gtcagtcatg aatcggctac actagactag acagaaaaaa taaggtgtgt agaataataa
    21241 aaaacacact ggaggatttt tcatg
//
LOCUS       DAFKHN010000049        21041 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFKHN010000049 DAFKHN010000000
VERSION     DAFKHN010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21041
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.049"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(55..684)
                     /locus_tag="LY912_001792"
     CDS             complement(55..684)
                     /locus_tag="LY912_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955470.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            complement(681..2057)
                     /locus_tag="LY912_001793"
     CDS             complement(681..2057)
                     /locus_tag="LY912_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBM6955471.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            complement(2137..3399)
                     /locus_tag="LY912_001794"
     CDS             complement(2137..3399)
                     /locus_tag="LY912_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955472.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            complement(3412..3759)
                     /locus_tag="LY912_001795"
     CDS             complement(3412..3759)
                     /locus_tag="LY912_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955473.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            complement(3779..4648)
                     /locus_tag="LY912_001796"
     CDS             complement(3779..4648)
                     /locus_tag="LY912_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBM6955474.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            4969..6396
                     /locus_tag="LY912_001797"
     CDS             4969..6396
                     /locus_tag="LY912_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HBM6955475.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTYGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTAPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCVSCPLLENCTLSTKHQKIVTRHIWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKTKKPM
                     AFYFKIMQRLTKRSGLITNSFLSTI"
     gene            complement(6418..7224)
                     /locus_tag="LY912_001798"
     CDS             complement(6418..7224)
                     /locus_tag="LY912_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955476.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(7312..8112)
                     /locus_tag="LY912_001799"
     CDS             complement(7312..8112)
                     /locus_tag="LY912_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955477.1"
                     /translation="MVGVSKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            complement(8451..9560)
                     /locus_tag="LY912_001800"
     CDS             complement(8451..9560)
                     /locus_tag="LY912_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBM6955478.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            complement(9550..10413)
                     /locus_tag="LY912_001801"
     CDS             complement(9550..10413)
                     /locus_tag="LY912_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBM6955479.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKI
                     VAKRRGMKNEE"
     gene            complement(10482..12317)
                     /locus_tag="LY912_001802"
     CDS             complement(10482..12317)
                     /locus_tag="LY912_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBM6955480.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKSVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            complement(12366..14756)
                     /locus_tag="LY912_001803"
     CDS             complement(12366..14756)
                     /locus_tag="LY912_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBM6955481.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMMLSTLIMPFSAIRAEADVTKPT
                     SAKFIETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            complement(15024..16271)
                     /locus_tag="LY912_001804"
     CDS             complement(15024..16271)
                     /locus_tag="LY912_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBM6955482.1"
                     /translation="MNMKRNSLGMVLLASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPIENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKPMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            16664..17080
                     /locus_tag="LY912_001805"
     CDS             16664..17080
                     /locus_tag="LY912_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955483.1"
                     /translation="MNKKRKLSVLITLVSILTILSVILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            complement(17097..17834)
                     /locus_tag="LY912_001806"
     CDS             complement(17097..17834)
                     /locus_tag="LY912_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955484.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(18256..18819)
                     /locus_tag="LY912_001807"
     CDS             complement(18256..18819)
                     /locus_tag="LY912_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955485.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            complement(18806..19333)
                     /locus_tag="LY912_001808"
     CDS             complement(18806..19333)
                     /locus_tag="LY912_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955486.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            complement(19356..20693)
                     /locus_tag="LY912_001809"
     CDS             complement(19356..20693)
                     /locus_tag="LY912_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBM6955487.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            20813..>21041
                     /locus_tag="LY912_001810"
     CDS             20813..>21041
                     /locus_tag="LY912_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955488.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYN"
BASE COUNT         5951 a         4219 c         3073 g         7798 t
ORIGIN      
        1 aaagcctgtt ctatttgctt caaaaagttc tagcaatctt tttcacctct actgctactg
       61 ccaaacaaat ttagctttat catgccatgt ttcagacatt acttttttac cattttcgtc
      121 aaatatcacc gcttcccact ttgctgttcc atccggctgt ttacaaatat ctgcaaacca
      181 taggatcgtt tttcgatcgt tgaatttcct tactttcttc tcaaatttat tgatctgaac
      241 tctattttga ttgctgttcc aacctactaa taggcggtta tctgattctg taccatgaaa
      301 accaatggga acgatgtggg ttctatcaaa tgcttctttt ccttctggat agagcattgg
      361 tctaagtttc ctacgtttca agtcatctct tgcttgatac cgccatgccg attttggatt
      421 gaatttaata gctatttgat gcttgctttt gtcatggtaa aaatatgcga catcggcttc
      481 agctccaagc aacttttctc ttgcactatt tgattcaaac ggtttattca cttctaaaac
      541 cttcacccct aaaatgccat gatcaagcat ctgtttagga gttagtaccg cttttttatc
      601 tcttttcttc gctcgtttca caactacttc atctgtatat ttatatggag taagccatct
      661 taaaaaagaa ctgacgatga tcatttatgc acctgttttt ttgcttttaa cattttttgc
      721 atgataggtg aagtacttcc atttatttgt ttcttttcag atttatcagt tgtgatcact
      781 acgttttctg agccttttgg atcattagct ttaggtttgg ttttagatgc aatcggctgt
      841 ttattattcg tgttgtttga ggtttgcggt tcaggatcag cttttcctaa tgcccttaaa
      901 actttttcta gtttttctgc ttgcagtttt tctagtgttt tagctccctg ctcgactttt
      961 tcttctttgt tcttttcaag cttaatagca aacgcactct tcttttcaat tgatggctct
     1021 ttagatgatg gatttgctaa aggtgtgttc aaatttcttt tagcagattt tcttacagga
     1081 gctttaccaa ttccaccaaa atcctcgtct tcaccgccct caccacgagt ttcagctacg
     1141 attgctcggt aatcaacata ttctggttct ggcatagtat ttctaaggtg attgaagatt
     1201 gtttcaattt ctttgttact gatgtaagct ccctgcgctc taaccatact tccatcaaca
     1261 agcttaataa gcatatctcc ctttggactt agactttctc caccgccttc atctaataca
     1321 atcctacttt ctaaatcact tgctaccata aggcaaacac gtgacggaaa attggctttg
     1381 ataataccag tgacaactgt tgatcgagga gattgtgttg ctaagataac atgaatacct
     1441 gctgcccttg ccatttgtcc taattgaaca atcaaacctt ctacttcttt atgtgttcca
     1501 accaactgtg aatattcatc aactaataag atcacatagg gaaatctatc taatccattt
     1561 ttttcggcat attcgttata tagcgtgatg ttttgtaacc ctgctttttc catcagtttg
     1621 taacgttcat gcatcaagat cacaagatat tcaaaaaaat cataagcttc atccatatct
     1681 gtaattggat cagccaacat gaacggcaat tttttgtatc ttccaaattc aacccttttt
     1741 gggtctacaa ttcctatttt taattcatca ggcgttgagt gacacattac tgtaacaaga
     1801 atttcattca gtaatactga tttccctgat cctgtcgttc ctgcaaccaa catgtgtggc
     1861 atttcgctga tgcaaaaatg agcaattgtg ccatcaggct taattccaaa aatagcatct
     1921 gttgggtctt tagcctttgt gttcaacata ttgacactga attttccatt aagctttata
     1981 ttaggttctt tatctagcaa aatagattca gctttttcgg ctctcttttt gactttctct
     2041 aataatttca tagccatttc tattcctcac ttttctcggt acttttctgt ttgtgaactg
     2101 gtagtttgta ttttctgttt ctatttgtga tgtcttctaa aacacgctat tgatcattga
     2161 tggtacatca attggaatac gatcattttc tcctaatggt aaagtaattt gaatacgccc
     2221 tgcgttgatc cgcacgatta cacctgatat atgcaagtaa gtttcaattt cttctttcat
     2281 tgagcttagt tgaatttttc tggtacgaga taaagtaaac aaatattcaa tagatgtatt
     2341 cccaacgtgc atatctgtta gacttgcagg tacgtcagca gaagatagat aaagttctaa
     2401 agattgcttt tgagtttcgg catattttct agctttttcg gtttggtttt ggatattttt
     2461 ggaattatcg gcaaagagat tgattggaaa agaaaattgt gaatttgaaa ctgcgattga
     2521 agatgttgct ctttccgttt ctttgttttt ggtacttact ctttccttac gttctctttc
     2581 aatatttact gatgctcgga aaatgaaata atcgcctgaa acttcatctt ctttttcacc
     2641 aaatttggct cgtccgcttg ttgctcttgt caggatcgac cctaaatctt gaatttgtcg
     2701 taaaactgtt tctctaactt tcttcccttt tggttgcggg atttttacga tatattctcg
     2761 aatatcttca ttgacactta gatcacgtct tgtatgaaca gaaattttga tatttttaag
     2821 cgttgatagc acatcggatt ctaattgcgt tttgtttcgt tttctttttt tgttgttcgt
     2881 ttcatctcct ataatcttgt ttggatcata cttcacatcc atagcttcta gagcttctct
     2941 tttcaacctt ctactttcca tatcatcaaa aaatggtctt tgttctccat agtgatgcct
     3001 gaacatcaaa gtaaccaaat atccaacaaa gaataccgtt cctgcttcta atactaaaat
     3061 agagatgtct accaagtgta gctttgcaaa aaagctttgt acattatatg aataacttaa
     3121 ataattggga aaaaacgcat tgagtaactc tttaaacatc tcttttaatc ctaaatcatc
     3181 tgttccgtta acatcattta acgagacaag aatacttact aaggtatcta caagcagttg
     3241 tacaaccttt gttacccaat gcaaaatata tatgccaatt gcaccaacta ccaatgcacg
     3301 tccaaccaga tatactgatt tagaaaaact ggctacagga taatattttt ctccatcgct
     3361 tcgcttatat tcctttaatt caatggattt ttcgctcatc tgaatatctc cttattttct
     3421 ttctgatttt ggttcatcgt cacttatgct gtcctcacac atctgcgtat ctttaggaat
     3481 gattactctg atttcgtcta acatttctct ctcaatgatc atcgcccctt ttgtactaac
     3541 agttttctct gataattcaa cacatttccc tatttcagaa tctggatcaa aaatagcctg
     3601 ttctacgtca aaatgattct tagctacata cacgatactc attgtttcta actctctagc
     3661 aactgaatat ttacccttct tcagaagata gtagccattt ccttttttta ttcgatttgc
     3721 aactgattta tctaatccat tgatgcttat tgtttccaat tcttcacctt ctcaatttct
     3781 aatctcttac ccaagtacca ttttgatagt tgatgttgat tcctttttga ttgttaaata
     3841 cataaacatt aaggtttacc gtttttccat tatcgttaac tgagaaagct tcgacatgag
     3901 aaccacgagg aactaattca ttccctttat aaattggatc aactttatac aatacttttt
     3961 cattcttatt tttatagatt gcatcacgta caatcgtttc tgagtaagcc atccctccat
     4021 tctgatcatt tttcccaaca ttttgcgctc tcgttccaag tgttaaattg tgtacctcca
     4081 tatctcctcc tagcgaccat gctaatgaat gacttttgtt atagagataa cctttatagc
     4141 cttctagctg agtgatttca ttgtttgaat ctttgccgac ccaagtatct ctctcttgat
     4201 caaatactcc atccttgtat tctcctgcaa tatggacaga acttttgaaa gatggacgtt
     4261 ccacattttt agatgagtga gaatttacag catcataggt gatcaacgct tcaacatctc
     4321 ctgctcttcc aagttgatct aaatctgcat aatttaccca aaaggtttga ctgccttttt
     4381 ctgataatgc ttcatggtct tcttttgtca gtgtatattt cccatcatta atgtttacga
     4441 tattatttgg atatttgttt ggatcataac gtatccctaa aaattctttt gattcactgt
     4501 ctgctttatt acctacctga acactacttt tgatctgaaa atcatgttcc tgagtactgt
     4561 tattctgaaa gtaacccttg ccactaagac caaccgcaac taaaaccaaa attcctaaca
     4621 acgatcggct aaacttcttc tttttcatac caccattcct tttattgtgt tatcataata
     4681 agataaatat ataataaact atattgtaaa ttttgtcaaa tgtattttta tttattccca
     4741 ctataaacct tgatatatag ccaatttaaa aaaggatggc aaaaaattat caagttaaaa
     4801 aaataaattt tgaaccaaat tatttttaat aaaatagcta gtttttttat caaaaaaaat
     4861 agagcttttc agctctattc agactgtaga caaactccta aatttggagt gttgtttgca
     4921 gttttttgtt ttatactaat tgtataaact attctgggag tgattctaat gatgagaaaa
     4981 caatcgattg aaggtagaaa tcaatttgct atgttaacaa ttgatgatct tgtacctaaa
     5041 gatcacttag ttcgaaaaat tgatgctgcg attcagtttg atttcattta tcccattgta
     5101 gaatctacgt attcaaccta tggtcgtccc agtattgatc cagtggtctt aattaaatta
     5161 gtatttatcc aatatttatt tggtatccgt tcgatgagac agacaattaa agacgttgaa
     5221 acaaatgttg cttaccgttg gtttttaggt tattcattcg aggatcctat cccacacttc
     5281 tctacttttg gtaaaaacta tgttcgaaga tttagagaaa caactttatt tgaagatatt
     5341 ttctctcata ttctagaaca agctgtaaaa gctggcttcg ttacggaaga caacctttat
     5401 attgattcta ctcatatcaa agcaaatgcc aataaacata agttcacgaa agagatgacc
     5461 tacggtcaag caaaagctta tcaagatgaa ttagaagatg aaataaataa agaacgtatt
     5521 gctgtaggaa aacgtccttt tacatgggac acagaaagtg agttgagtct tcaaaaaata
     5581 agtcattcag atccagaaag tggttactat gttaaaggtg aacgagaaaa acaatttgct
     5641 tattctgcac atacttcctg tgaagataac ggttttatct tatctacatt aatcacacca
     5701 ggaaatgtgc atgacagcca agtcgcaatc gatctggtta aacagtcgaa aagagctttt
     5761 ccaaatataa agcgtgtggt tgctgatgca ggatataaga cgcctaaatt tgttcatttt
     5821 ctgtcacact tgaaactcta cccgattctt ccatatactg cacctcatgg agtgaaagga
     5881 atgtttcgta aaaaagactt tgtttatgat gcctattttg actgctattt atgtcccaat
     5941 aatcaaccgt tgttattttc aactatcact cgtgatggtt atcgaaccta taaatcaaat
     6001 ccaaaattct gtgtgagttg tccattactt gaaaattgta ctttgagtac aaaacatcaa
     6061 aaaatagtga ctcgacatat ttgggctgat cttatggatg aacttgaaca ccaacgccat
     6121 acggcgttga atagagaaat ttacaaaaag agaaaacaaa ccattgaacg aatatttgca
     6181 gatgcaaaag aaaagcatgg tatgcgttgg acgaaatatc gaggtcttga aaaagtcgcc
     6241 acgcacacga tgcttacgtt tgctgccatg aatttaaaaa aactagccac atggctatgg
     6301 aaaacaaaaa agcctatggc tttttatttc aaaattatgc aaagactaac aaaaaggagt
     6361 ggcttaatta ccaactcctt tttgtctaca atctgaatag agcttttcag ctctatttta
     6421 ttcaatatca ttttgatcaa ttaataatcg tacactccaa ttaaccgagt tttgatcact
     6481 caaatattta taatctttgt catcaaaaac cagttgccaa actctggtac gaacagtttc
     6541 ttcgtccact tcctcatctg aagagtattg cgataatgct tcttcaacta tatactttac
     6601 aacttcctca aaatcagtag gaactttatc aataaccact tcatagtctt cttgttttac
     6661 gatattggga tcaatatgtt catccaaaca tacctcagtg agtttttctt tcacttctgt
     6721 atctctttct gtttttaggt actctgcata gtcttcctta gaccattgtt tttcaagatc
     6781 atccgctata cttttaataa aggattcttt atttaaccaa ttatctgcgg tatctatacc
     6841 ttcaaactca aaagctgttc cttctatacg tgatttgacg aaagcgtcaa ttttcttgta
     6901 ttgattattc atttcccatg aaacacactc atcttcttgc gtaatatcat aaattttttc
     6961 ggaaaaacta actaattcat tccacgattt atcctcggca acttgactta gtttcgatgc
     7021 aataaaagga aattttgctt ttaagtcatc catattcttg atctcaaatt cgatattttc
     7081 ttctcctaca gctgaaatcc atgctgaaag attgattgca atatcgctaa agtcttctac
     7141 attttcgaca tttcctgtat tatcttttat tactgcttct aaagccatat cggttgttgc
     7201 actcatggtt tgatctcctc tcataataga gcaaaaagcc ggtttaaccg actttttgca
     7261 tggtacgttt tgtttggtag ttttctgctt gtgtttatgt tgaaataatc cctatagctc
     7321 ttcttttaat agttcttcaa ctttatctct taactctccc tgaccactct ctaatagatt
     7381 taaatagctc atcagaatat ccgtttcata cgtttttaat tcagctctat actcactttc
     7441 tgaatatgat cgtaaatacc catcattgct aaatgcaact agatcatctt gaaagttcca
     7501 ttctcctaaa tttgttttac ttactgcttc ccatggacta ttactaaaca tttcattaaa
     7561 gaaatcttcg tcattttgat ataccttcaa ttcaggaaaa tagttgctgt cttcattgat
     7621 ttcttgcacc atttttccaa gttcttcttc agataattta ccttccaata attttacttt
     7681 ttctctgtca tttgcataag ccatttgaac ctctcctttt tctttttcaa tttcttcagg
     7741 tgtttgtttt ggcgtaactt tcaaatctat tccattgcct attagaccta ttagataacc
     7801 atagaacgtt ttaaagtcac ttgtagcaag agatttggca tcagggtatg tatcccctcc
     7861 aattttatct aaaacaaaat cagcaatcgt tacccaagga gaatatatcg tacatactac
     7921 atcccatgta gcatcttcaa tattcgtcca tgtcggaaag tcattttcat tcaaatagtc
     7981 ttttttcatt gtttcgatca gagtttttcc actttcgttt tggcttagat attcaacaaa
     8041 ttctgcacca tcaaacctgc tactaaatag tttagctaat gagtctaaag ctgtttttga
     8101 tactcccacc attactacac ctcctattaa tattttacga tgacttgttt ttcattcaca
     8161 aataagattt tctacatctt atctattgct ttatagcttt tccatacatt atttctaaat
     8221 acaaccaata accctattaa attaagcttt tgagtttatc ttttctaata atattctgat
     8281 aaatattctg ataaaaaaat ttattgtatt tttttcttga ctttttcttt agaattaaga
     8341 tcagttttga ttttatttaa aagtgaatct agctctattc aaaataaaaa agagatcaat
     8401 aatagtatca atcccttttt actgtactct atcaattttt ataatcttca ttatgctttt
     8461 cgaaactctt tgattaaaag aataagaacc tttagacttg ctaatgctcc tattacagtc
     8521 caaatgacta aaagcatttt ctgatgttta ttggtaattc ctgtaaatat tgaacttgcc
     8581 ttttcagcaa acgttctgtc ttgcatctct acgctacctt gttccggaat attaagatca
     8641 ttatttccat ctaattcctt gttggcacga tcaacatctt caaataaatc attagaagat
     8701 gtaacagttt ctgtcttatc tgaaacggac tcgctatcaa tggcatcagc gtatgcggta
     8761 ttgccaactg ttacttgtgg cgtgatgtat tttgcttttt catctcttag acttctaact
     8821 aataaacgat cgtagttctg aggatatgga tgacaagtat aaagtgttaa catatctaaa
     8881 tcaggaatat cagtcagtgt tgaattctga ccgtaatttc taataacgtc tgttcggaaa
     8941 accgtataaa ctgctttttc accaagataa tctatataaa tgtggtctcc ggctactaat
     9001 tgatcaacat aaagaaattg tggtgacgta taaccgccac gatgacctgc tattactgtt
     9061 tgatgacctt tacctgataa aggtagacta gtagcactca tttgtgccac acctctatat
     9121 aaatgctcct gtgaagcgcc tagaaacaaa agctctagca catttatttt tggaatatag
     9181 acataaccaa ccgctcctga ataggtagat ggttcaaaat ctttcgtttg attttttgaa
     9241 aaaacatctc ctgtgtatgg attgaccttt ccttcagctt cacgaatatc aaatgatcca
     9301 ccgtctgttt cctgagtatt gtctactcct ttatctgttt tctgagtatt gtctaatcct
     9361 tggttaccgc tgttcgattt tatttgttcg actttttttg ccacttcctc ttttgaagga
     9421 gtttgttttt tctcaatttt ctcttggatt tccgccacat tctcttttgt tttgaattga
     9481 tgatagagct gatttgcagg ataaattgtt aaaaccaaag tgcaaataag agtcaaaaaa
     9541 agtagtattt tattcttcat ttttcattcc tcgtctcttt gctactattt ttttaataat
     9601 gactatcaca gctattatta ataaaacccc tacaactacg ataggatacc agttcatctg
     9661 cgcctttacc tttaaatctt ctttcttctt ttctttctca acaatacttt tttggtaagg
     9721 tatgctaacc cctctaacga gtaacctatg agaattatct ccaacaggtg tacatgtcat
     9781 aagtgttaca taatcttttc ctgccacagg aagcaaatcc tcaaattcgg ttggtagaat
     9841 tgtttttatc cgatctactt gataagcaag ttttttccct gaaatatcaa taaaaaattt
     9901 atcaccaagt ttgagcaact ctaaatctgt aaaatatttt ttattaggaa tgcctgaatg
     9961 agctgatata acagaatggt ttccaatccc accagttgga taatcagttc cggttaatat
    10021 tcctgctcct gctgatagtt ggaaatcgtt tacaccatca taaattggca aatccacatt
    10081 aatctttggt ataagaattt cacccactaa ttcacctaat ttatccttct gaagatttcc
    10141 atttgacgga atattgttat tatcttcagg aatcgtgact gaggtttgtt ctgtgtcttt
    10201 tcgtttccta ttaacttctg aatatctctt gaagacttct tcattctcct tttcagaagc
    10261 ttcatcatat ttttccttat aggagtttag tgtttgttga gtttggtagt aggtataagc
    10321 ctgagtaatt acaggatata gacctactcc taaacatagc aacatcccaa tttttaagat
    10381 gatcaacttg atattcttct ttttcatgct catacctact tttcacacac tttttaaaaa
    10441 gaaaccctag agccaaaaac actctaggga attttatttc attaagcttt gtgttgttct
    10501 cgtttgtaga caacatatag ccctgttcct gccacacctg caaccactag aaatactact
    10561 gttccaattc cacctgtacg aactgtttca ggtgttttaa ggttcttgat gtctgttact
    10621 tcgctagaag catcatcatt cgataccaca aatggaacat catttctagt tggtgtatat
    10681 cctgaaggag caacaacttc ttcaagagca taatcattga tttttttatc tgtgattgtt
    10741 ggattacctt gtttatcaaa atctacatca taggtatatt gcaagccttc aatttggaac
    10801 ttaccatctg atccggaaac gaattcagta gctttagatt tatctgcaat ccaagtaaca
    10861 gatttcgttg ttggatcttg ttttaggtaa gtaactttat tcggatcaat tttgttcttc
    10921 actacaaatt ttgctccact caatgctttg cttgtatctc catctgtttt aatgaattgg
    10981 tgatcaccaa tgattgtata agcgtgatca actggtgttt cgtcttcggg ttcatatcca
    11041 ttgttgtaga tcgttgaaac atcattctta agtggtgtat ccattttagc tttactatta
    11101 gtatgagcgt tcatcaaaat tgtaaagaag cgatcccctg catcaaattg tttctgaagc
    11161 ttatccatac ctgattcagt aaagacatag tttgtcgttt gtccgtcacg ttcgatactg
    11221 taatcagtat ctaaagtcat tccttcgatc acttctgatg aatcataagt taactctgca
    11281 cctagaacat ctttgacaac atatttttcg taattaccaa tattaccagg aattgatggt
    11341 ttcaatgtat attgaacatc ttcgccagta tcaacggttt ctttatcaat taccttagta
    11401 attacaggtc gtttgtagtt ggtaacatca agaactactt tagcagtctc cccacgttta
    11461 acgctaaatt tgaatttttt accatctagt aaataggttg ttttattagc atctgttccc
    11521 aaatcggttt ctaggaaata atagtcacct aattccaaac catctacagt taatttacct
    11581 gtgctgtctg ttttataagt tccaacaacc tgatcagatc catcatcttt tcgcaattca
    11641 aaaacagttc cggcaagagc ctttccatct tcgtcttttt tatcaagctc tgctgagttt
    11701 aattggaaat agtttttagg atagacatgt acatcataat taaagtattg atcatctgat
    11761 ccgtttagtt caggtacgtt aacaatcata ggatacgctt cttcaactac acctttgact
    11821 gttcctgttt caacaatcaa atacaagtta tctgttaaat cgtctgtatt tacttgtata
    11881 ggtatgtcta tattcccttg tgaatcagtc ttcattctac ttacttcact gtattttttg
    11941 tttagtaata atcgtgcttt agcatcatca atatgttgac cttttgtagt atcactatcc
    12001 gtccatccca aggatttagc ttcatcttta gtaagtttca cataagagaa ctcaacgcct
    12061 tcaagaggtt ttacaccatt tggtaaagct atttctttcc ctttgttatc aatatctgag
    12121 acagggttcc catccccatt agtatttgtt actttatgga tatgaatcgt tccagttcct
    12181 tgataattat agttttgttg tgcatatgct acttgccccc ctagtccaag gctagaagag
    12241 attgagcttg cgcccaatcc cactcctagc aaagtaccaa atagcattaa atttgaaaaa
    12301 attttttttg atttcatacg tcagccttct tttttcatat ttacttcttt tccattaaca
    12361 cttttttatt ttgctttgtg ctgttctcga taatacagta gcaccatact caatcctgca
    12421 attagaaata caagaaggaa ggctgatgta ccgattccgc ctgttcttac tgtttcaggt
    12481 acaaggtgat taattactgt atattcaaag gtttgtccat cgtcagcaac ggtgatgcct
    12541 tctttagacc atttccctgt ataaccatta gggttttgtg tttcttcgat tttgtacgtt
    12601 ttgttggcaa caatattaaa tgttgccaag ccattgctgt ccgttttttg tacaactttt
    12661 acacctttgt cgtctgtcaa agtgaattct gcgtttgcta atgctttccc ttgatcatcc
    12721 actttatgaa ctttgatcac accttttttc aaagtgtttt tagcagtata ttcaaagact
    12781 tgtccatcat ctttgacggt aattccttct tgtttgaatg cgcctgtgta acctgttggt
    12841 acttttgttt cttctaagtt ataagttttg ttcgcaataa tgttgaacgt agccagacca
    12901 gttgcatccg tctttttaac ttcttttaca cctttttcat ccgttaaggt gaattctgca
    12961 tctgctaaag gttttccatc ttgatcgact ttatgaactt ttactacacc ttttttcaaa
    13021 ttatttgtag ctgtatattc aaaagtttgc ccatcgtctt taacggtgat accctcttgc
    13081 ttaaatgcac ctgtgtaacc tactggtact ccggtctctt ctaggctata cgtcttgttt
    13141 gctacaatat tgaagcttgc aagtccattt tcatctgttt tttctacttg tgttgcacct
    13201 ttttcatcgg ttaaagtgaa ctctgcattt gccaaaggtt ttccatcttg atcgacttta
    13261 tgaactttta ctaaaccttt tttcaaagtg tttgtagctg tatattcaaa agtttgtcca
    13321 tcatctttaa cggtaattcc ttcttgcttg aatacgcctg tataaccagt tggtactccg
    13381 gtctcttcaa ggctgtaggt cttgtttgct acaatatcga agcttgcaag tccgttttca
    13441 tctgtttttt ctgcttgtgt ttgggatgaa tcatccgtca aggtaaattc agcattagct
    13501 aatggttttc catcttggtc aaccttttta acttttactt tacctttttt aattgtgttc
    13561 gtagcagtgt aactaaattc ttgtccatcg gtattaacag taataccatc ctttttaaat
    13621 gaaccttgat aaccttcagg aacttttgtt tcttctaagc tgtatgttaa gccttgttgc
    13681 aaatcaaacg tagctaaccc atcatctccg gttgtcttaa cagatttagc attgttattg
    13741 tcagttagag taaactccgc tccttttaaa gcatttccat cttgatcaac tttcttaact
    13801 gttacctgac caacagctct tgtccattta gcactcaaag atttagagtc ctttgtttct
    13861 gaagtagtga tcataactac ggcatcttga tacacacctc gtccatcaaa agtaaaagga
    13921 ttggttgtgc taacattagc agtaccttta aatgacaaag taccacttgg tgtagtcaca
    13981 ggtactttaa tagtaaaact tgaatttaat ttcacagtgt tgttagtaat ttctttacca
    14041 tctgcatcat aaatcttcat accagctggt tttgctgatg taaaagtgag cttcgcatta
    14101 ccagtcttat ttgatgctgt tttatatgtg aaagtgtgat attttccttc gtcagctgtc
    14161 ttagaagctg tgatagaaaa ctcagtgttg ggcgtatctt ttccattctt agcatagtca
    14221 taaatttttt caaatgcttt ttttacacga gctgtttctg cggcggtatg gtttggatgt
    14281 gaccatacaa tctgtgaaac tttaaagttt ccggctaaaa cccatgaaac taattgtgtt
    14341 gcataccatg cttctgtatc atttcctgca cccagttcct ttgctgtttt tgatggaaaa
    14401 ccacctttaa acatacgata gaactcatca ctgccagctc ccttgtactt caagcttccg
    14461 gctccacttc ctgttgggga tggcaattct gaatccatac aatatccaat atttccatga
    14521 gaatctttaa attgacttga aatcatccat tcatttggat gattcggcat attaacccta
    14581 atataaccgt ctgtttttac gccagtttct ataaattttg cacttgtcgg ttttgtgaca
    14641 tctgcttcag ctcttattgc tgaaaaaggc attataagcg tagataacat cattactaaa
    14701 gtcgcaaaac aataaattat ttttgatttt aaaattatcg ttttttcatg cttcatctct
    14761 cgttactcct tctttatacc agttaggcga agaaaatgag ccacgatatg tcggtgtggt
    14821 aatgaccttc gcgcccattc ctaagttaaa atcaccacac ctattaatca tttttttcgt
    14881 tgaaagcaag ctgtttcaac gctctagtat tcatagcatc acccctttta gttctaccca
    14941 ccatgagcaa caagttttct aagtagttaa gcaaggacaa ataaagacta tataactact
    15001 tagtatataa acgatatctt ttattaacgt accgaaaccg ctaattgaga tacgttatat
    15061 gctgtttcaa atgatcctgc attaatccaa cttgccccaa acacaggatc gacaacatgg
    15121 taaaaaccgt ctttaaatcc atcaacggct actacatgtc gattccaaat agcatcgccc
    15181 caaaacattg gtttatgttg agcaggttca aaggcataag ttacccacgc tactacagga
    15241 tttccattta caatctcatc ttttaatcct tgtaccgatg aaccagaaat atctacaaca
    15301 tttccgccat tagcaacacc ccatgaaact acaggagccg gattcatacc ttgataagtt
    15361 ccatccacat tgtgtctcca ttcaccagaa aaaccattat ttggattatt gtcaggagat
    15421 agtggcattg atttaacaaa agtcattaaa tcttgatttg ttgcaacacc tttataatgt
    15481 aacgcttcta gcaaagatgt tccttcgcaa agcattgtgt taccttgact aataaatgga
    15541 acgcctagca caacattagt tggttgttcg ggtttacttg gtgaagtaga actgtcagtt
    15601 tcatcactcg aacctgtttg tgattgatca ctagaagatg tactggttga ttcatttgca
    15661 tcatttgatg ttgattgtga gttatttgtt gatgttccag tatcagcttc cgtagtgcta
    15721 ctttcacttg ttccctgtga tgcttctttc tcacttgtag aattatttgt attagatgaa
    15781 cttgctccat caacacttga agcacttgtt tctgtcttat cagaagtgtt tgctgttggt
    15841 tccgattctt ttgtagtctc ggattttttg ttctcttgct ccgtattttc aataggatca
    15901 ggtttatctt tttgaacagt ttgactaact acttcgccat ctgcttcctt aactgttaat
    15961 gtatctttac tgatgttgaa agttcgtcca atcgggatag tccgttgttc tccttttgcc
    16021 aaatcaacat tgttcaattc ggcaaactca gcaacagtag tcttgtaacc taagctttta
    16081 agcttctcta cagttgacca aatagtatct ccttttttga acgcataact tgattgtcct
    16141 gttgtaattt ggatttgatc cggtgtgttt gcagtccatt catcagcatg tgaggttact
    16201 ggtactgata accccgcaag tacagctgat gccaataaaa ccataccaag cgaatttctc
    16261 ttcatattca ttccttcttt ttgtttttat tttctgtttg tgatcgcaat gcttctattc
    16321 cttcttccgt tataatatag gttttgtcac ccactttctt gaacgaacct ttaggcaaac
    16381 gatttggata atagttgatt atgtttgtaa cataatttct acctttaccc aaaatcaaac
    16441 ttgcttccct tgcggtatac aagttgtatt tgtctaggtt caatttcttt ttgtttgcga
    16501 tttagaccta cccctttcgc aaaatttatt gtataataat agtaccattg cactgtcata
    16561 attgcaatat ttttttgggg tttatcttca tttaatagcc taaaaaggct tgttagataa
    16621 ggaatatcta actaatcaaa acaaaaaagg atgttaagaa aaaatgaaca aaaaaaggaa
    16681 attatcagta ttaattacac ttgtttctat attgactatt cttagcgtta tcttgtcgct
    16741 gaaaatattc aatcaaataa acacaagctc aaatgccaaa gatggaatag tcgtagaaaa
    16801 tacctctaat tctaaagaaa ctggtactac tacaaaaaaa gacaaatctg ctgagatcac
    16861 tacgaaaaat tatttaataa agactgttta ttttgatgaa cgaaaaacag caattctcaa
    16921 agatgaggaa ggatcagaat taaagctacc tataacggta tccgataagt tcaatggaac
    16981 gttctcctta caaaccgctg aaggatcacc tgacaatctc aaagttgggc aaacaatcat
    17041 tcttggtaaa aacgacgaac tgtattcatt tgtaaaataa aaaaatggag caaaggctag
    17101 tcaagccctt gctccatttt ccattcttca agaggtgtag ctatttcaac accaaagttt
    17161 aaatactgtg gatgctgtag atacatgata tccattctat tttcgataaa ctcttttaac
    17221 gttgagtaga tgtatttttc taatgctata tctgcccaac taccataatc aagtttattc
    17281 gtgatcttga cgtttatttc aatttgagaa acatcaatat tttgaacatc aggaaactta
    17341 ttcagtctta gctcttctct aaccgcttct actagcggtt catattgtcc gcctagttcg
    17401 ctaattgttg aaactatttc atctgaattc caacgatctt ccaatacctt tgctacattt
    17461 tctttaggcg gttgtctttc tataaattct tcaggtgttt catcaaactc tactctaaag
    17521 ttcaatttat tttgattgtt agcatacata taatcatctc tgtttgattc aaaaaagtta
    17581 cgaattcctg tgtctgattt atcacttaac tccttatttg ctaaagtagc ccaaaaatcc
    17641 caagttcctt tattttcagt atacaaagta aaattaatgt ttatatagtt tgcagtttca
    17701 ggataccctt gctctctaag agcatcttta acaatcactg ctaagtcagt ttcaaaattc
    17761 tccataaaaa attcactaaa ttcttttgga ttccacgttt cttctaataa cttttctaat
    17821 ttatgatctg ccattattat tctcccccac tttactttca atcttatatc taaaactgct
    17881 taaaattaag agctatacct tatcataaaa ggtattttat gctttattta agtctacaat
    17941 tctatattac aattatcatc tagaccattt tcttatgtca aataaaccat atatattgtc
    18001 tttaatagtt ttatttgact ttttaagaaa gtatttactt ttgacttttt ttacgtttta
    18061 caacatatac gtattgtaat gttcagctca atttattata atctaaatga attgattaat
    18121 aaaaattctg aggttcgggt tttttatcaa ttcttttctg tttgtgtttg tgatgaaaca
    18181 atcctttttc ggtaggtttt gttatcatcg tcagcacaaa gagctaacgt tggtaccgtt
    18241 agctcttttt ttattttact ctgctcttac atagctatct aaatcctcca aataaaacaa
    18301 ttgattttct cctatgcttg ttactccacg ccaaattgtt gttgttgctg ttgttggagt
    18361 atttcttgtc tgtgtaatca attcaaccat tttacctttt tgatttgttg tatagtaatc
    18421 agcagtatag ctagatattg gactattacc agtgcctacc atcgtgccag aaatatcaac
    18481 aggactagac tttactatct gaggaaattc tttttgtatt tccttcatat tcttcgtata
    18541 tttttcccat gaattccagt tgtaaaataa attaaagaat ttcctacttt gttccttaat
    18601 ttcagcattt cccaattctt tgtattgagc ttcctgcata gctttcactt tctggttatt
    18661 cttgactact tcgatttgtt tacttttaag gtcttccaat tctttgacat tattatcata
    18721 agcatttttc ttttgaaata gtaccacaca acaaaggatc acaattatgg aaagtattcc
    18781 gatcgccttt ttagcagtag tgatttcatg attttgcata aaaagcaccc ccagtcactt
    18841 tcttatcatt atttagtgtg atggttaatg tggtatcata cacttttttt ccattgtatt
    18901 gaacttcaaa atcggtcaat gcttcataca acccactact agatgtctta attccaaagt
    18961 ttgttagctt aaaagtaaaa ggcttatagt actcgatttt ttctttctca ctactcttat
    19021 cagtaattgg tggtttacct gttacaataa atagttttct caaaaattct tcacctgatt
    19081 gatctgcaaa cttattttga actgatccat tcaacatttc ttgaatatca ttttctaaat
    19141 ctttccgtaa tccatccacc tcatttggtt taacctcttt aaagaatgtc agcttatctt
    19201 caatatgcac actgtgtttt tcagcttcta tgtcctgatt ctgcttattg aagaatagga
    19261 ttccaacaag cagtgctaat aacataccag aaagcaaaga aatgataatt gtatctttca
    19321 ctttactatt catctatatc gtccttcatt ccaatttatt tttcgatttc aaatttagct
    19381 tttcctacac cgctaaagaa atgcacatta tctgatccgt ccactccatc aatcaacgtt
    19441 accgaaactc cccttgttgg agcttgggtt ggtggaacat taaagttagc acatagaaat
    19501 gatccatctt caaacaccgc tataactaca ccagtatgcc ctgcatctcc aacagcccat
    19561 aaccatccat ccgaagcact aaacccataa cctacgattg gtttgttcgt tatttttgct
    19621 cctgccgatt tgtagctttc ccatacataa ccaccatttc cagtagtcgg ttgattccca
    19681 tcgtataatt ggctcatata agcccacgtc aactctgtac actgaccttg atatattccg
    19741 ttaaaaggtg aagttgacca atctggttct ttgaattttg gtagcgtgat cgctttccca
    19801 tattttttca aagcttcttc ataagtcata ttcgctatta cttgaccttt tttaccgtta
    19861 atttttcctt ctttcccaat tgatccagaa ccagaattag cgtcatccgt agttgcacag
    19921 gcatcttcta ctgttcctga tgctgaactt gatgaattat tcgatccatc tccggtactt
    19981 gaacctccgg atattttatt gatcttactt tcatcttttg caccgtccat acccttgctt
    20041 ttcatgtact tccagatttc ttttgcattt tcaccacgta cagctattac agctgattcg
    20101 gaatcagctg aaatttccca gtttttatga aaagttactg cattttctac gacatcatca
    20161 gaagcattta aagcataatc ttttaatatt cctacgaatc ccccatcacc tttgaacata
    20221 aagtccaatt gggcttctgt agtccaccaa gaaccgccat tatttttctt agaccaatca
    20281 actaatgctg tatgtcgccc agctgtccat tgaccatagc caatacccat cagaccatca
    20341 gtaaattgtt tgatgaagtc aacttctctc tgtccatctc cgtaataccc ttctactgct
    20401 cgaggatcaa tacctgattc ttgtttccag ttacctaaaa tacctgcaat actagcacct
    20461 gataagccat attctccatt catgtatttg taaatatctt caatattttt ggctacatca
    20521 cctgttacag cgccacttcc agtatcgttt ccatcgctat ctgttcctga cccactacct
    20581 tcagtagtac agttaaattg tgcatcataa gtagctatcc catcagcatg tatcacttgc
    20641 ggatttattg tgattacact cattgcaatc cctgtaaatt gcaccattaa cataagcaat
    20701 gtggcaatct ttctcttaga ttttttcaat aactacgccc ccaaaaagtg tactttttta
    20761 tgttattatg ataatataat aacataaatt aatagaaagg aaaagctaat aaatgactga
    20821 taaaacaagt gatttaccta aactagctcc aaaaacatct cgagtaaaga gcaaaaaaga
    20881 tggaaaaaca aaaaatgctg taaagaaaaa gtcagtaaaa gaaacatcct cgttactact
    20941 tgatattcca atgagttctt ttgatgacaa tacggacgaa acttctgtta aaattgcaac
    21001 tcacgttgga atgaacaatc aaaatgattc tttttacaac t
//
LOCUS       DAFKHN010000050        19717 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFKHN010000050 DAFKHN010000000
VERSION     DAFKHN010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.050"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            289..606
                     /locus_tag="LY912_001811"
     CDS             289..606
                     /locus_tag="LY912_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBM6955489.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(697..1062)
                     /locus_tag="LY912_001812"
     CDS             complement(697..1062)
                     /locus_tag="LY912_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955490.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1270..1752
                     /locus_tag="LY912_001813"
     CDS             1270..1752
                     /locus_tag="LY912_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955491.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1949..2839
                     /locus_tag="LY912_001814"
     CDS             1949..2839
                     /locus_tag="LY912_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBM6955492.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            3165..5639
                     /locus_tag="LY912_001815"
     CDS             3165..5639
                     /locus_tag="LY912_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBM6955493.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(5742..7478)
                     /locus_tag="LY912_001816"
     CDS             complement(5742..7478)
                     /locus_tag="LY912_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBM6955494.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(7475..8179)
                     /locus_tag="LY912_001817"
     CDS             complement(7475..8179)
                     /locus_tag="LY912_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6955495.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            8310..8813
                     /locus_tag="LY912_001818"
     CDS             8310..8813
                     /locus_tag="LY912_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBM6955496.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8773..9111
                     /locus_tag="LY912_001819"
     CDS             8773..9111
                     /locus_tag="LY912_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBM6955497.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            9132..10550
                     /gene="ffh"
                     /locus_tag="LY912_001820"
     CDS             9132..10550
                     /gene="ffh"
                     /locus_tag="LY912_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBM6955498.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10662..11240
                     /locus_tag="LY912_001821"
     CDS             10662..11240
                     /locus_tag="LY912_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBM6955499.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            11244..11765
                     /locus_tag="LY912_001822"
     CDS             11244..11765
                     /locus_tag="LY912_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBM6955500.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11844..12398)
                     /locus_tag="LY912_001823"
     CDS             complement(11844..12398)
                     /locus_tag="LY912_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBM6955501.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12651..12926
                     /gene="rpsP"
                     /locus_tag="LY912_001824"
     CDS             12651..12926
                     /gene="rpsP"
                     /locus_tag="LY912_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBM6955502.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12938..13189
                     /locus_tag="LY912_001825"
     CDS             12938..13189
                     /locus_tag="LY912_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBM6955503.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            13313..14104
                     /locus_tag="LY912_001826"
     CDS             13313..14104
                     /locus_tag="LY912_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955504.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            14274..14795
                     /gene="rimM"
                     /locus_tag="LY912_001827"
     CDS             14274..14795
                     /gene="rimM"
                     /locus_tag="LY912_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBM6955505.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14785..15546
                     /gene="trmD"
                     /locus_tag="LY912_001828"
     CDS             14785..15546
                     /gene="trmD"
                     /locus_tag="LY912_001828"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBM6955506.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15682..16029
                     /gene="rplS"
                     /locus_tag="LY912_001829"
     CDS             15682..16029
                     /gene="rplS"
                     /locus_tag="LY912_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBM6955507.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(16161..17297)
                     /locus_tag="LY912_001830"
     CDS             complement(16161..17297)
                     /locus_tag="LY912_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBM6955508.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPNLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKMPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVDFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPKGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(17414..18106)
                     /locus_tag="LY912_001831"
     CDS             complement(17414..18106)
                     /locus_tag="LY912_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955509.1"
                     /translation="MKKVILGLVFGAFFLTGCSQSNVVDNTGKTNEKDSSVTLSESTT
                     QSSKNSQEVDGPLLKVGQWTKEKRDTSGKIELIGTASPQSDIPLGDIGIYISNIKLLK
                     YSNYADPSAAGYYDANNHKDSEGNFYGLQIAFKVKNNSEVDYGYNGLAHAILDNGQQI
                     DFSSDDLMHTMTTNSFFKKTESKEFYSLAYLDPSKVNDITKVTIKTGVLYNPSDYSTV
                     AESAESTFNINR"
     gene            complement(18244..18897)
                     /locus_tag="LY912_001832"
     CDS             complement(18244..18897)
                     /locus_tag="LY912_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955510.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKVSKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQDTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     GQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(18947..19375)
                     /locus_tag="LY912_001833"
     CDS             complement(18947..19375)
                     /locus_tag="LY912_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBM6955511.1"
                     /translation="MEMDTINLVEELKRKYRSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIDELKNLYGLPESAYRFLI"
     gene            complement(19380..19709)
                     /locus_tag="LY912_001834"
     CDS             complement(19380..19709)
                     /locus_tag="LY912_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955512.1"
                     /translation="MSITQLEEELNIPKNTIYQWKNRTPSTKRLQLVADYFNVTTDYL
                     LGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRVKDILIGTFWDIVKED
                     KEKGKKM"
BASE COUNT         6349 a         3482 c         3879 g         6007 t
ORIGIN      
        1 agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg tgaataagat
       61 aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac ctttctggat
      121 caacgaaagt atactttata tagtcataac gccgatggta actatgcact gtaacgataa
      181 tgctgctaaa atatcttttt acgaaaaaca tcacaaggaa aaacttaact atggtattat
      241 ctaaacataa ttttttcggt atttaatatt taattaggag gtaatatttt gcttttttat
      301 agtaatttta tcttaatagt agcgatatta ttacttctga atatatggat ttttgatagg
      361 agtagaaatg caagtatagg ttttagaact aaacgaagtc tgtcttctaa aaaaaattgg
      421 gtatactcac aaactatttt ttatggagga attgttttaa ttagtttact ttcttcaaca
      481 ctttattctt tgaatattat agatgtttcc acctcaaatt caatatctat tattggaatc
      541 attattgctg caattattac acaactgttt ttagtgtttg gagagaagaa aagaagtaaa
      601 aaatagaaaa actagtgata gttttggtga tataagaaaa acatatatgt ataaaaagaa
      661 gaaagtagct tctctttgta catatatggt ttgtttttat ggatgccgag cttttttata
      721 agataaggct accgcccata acgacccaag gatttgtgga actaagtaaa tacctgcaag
      781 aagcaagatc agctgggtcg gttttaaagg atgatagaag taacgccatt cagtaaaatt
      841 ggcgcaaaat aaataggaag tgacagtaga tataatattg gcaatgaata aagatataat
      901 acgcctgttc ctttgaaaat aatatccagc aaaaagagat aaaaatatca atgtgatgaa
      961 cccgcttacg gaatgataac gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa
     1021 agataaaagc aacggaaggt ttttccagca agtttttatc atctttcatc accacctaac
     1081 aagtgttatt attttgttag ttttattgta aattgaatcc tgcaataatc aattactttt
     1141 tcattatttc tagattaaat gaataaactc tcatgccatt atctctaaaa aaaaagtttt
     1201 tccccctaat ttttttagat agaaaattgt atagtatgat gagagaaaaa gtagtttggg
     1261 ggaacgttaa tgagaagaaa agcagtaatc gatcggcttt atttattttt ttggtttttt
     1321 cctatcgttt tgctaccttt tacatgggta aatgctgttg tacaaggtgc ggagatatta
     1381 ggcctgatcc aaggaagcgg attagtggtt tctaggaatt ttccagcttt gactgttttc
     1441 tatttagtga taagtgtagg tctcttatta ccaaaatctc tgatcaatca ctacaattgg
     1501 cagctgcttt acttttcttg cttattagta tttacatcta tgttttcttt gctgcctcgc
     1561 ttgattatcg gccctaatgg tttgagcgag agtggattga aggattcagc ttattcctcc
     1621 atgtatttct tgacgatcaa accatggttc tatttagtaa ttgcctcatt tattcttgca
     1681 acattttttt acttctggac agaaatcagg ataaaaagtg aacgatctgt atctataaaa
     1741 aataactatt gatggtggat catcagtaaa aaagcatatg agctgcgtaa aatgcatgtt
     1801 tctcatatgc tttttttatt attatgtaaa gaatgcgaaa aacgtttaca tgatttttac
     1861 ataacttaac tatattttta cagcaaccat acgagggatt tacagtcgac tgataaactt
     1921 tagttgtaaa taagaaagga gcaataaaat gaaaaaagta ttgtttactc taggtatgat
     1981 gggaattctt ttagccggat gcggctcagg atcaggaaat acagatggct ctgccacaca
     2041 aaataattca agtgactcaa atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt
     2101 acagccgtta gtcgatgcag cacaagaaag ctttgtacaa gaaaatccaa attatcaaat
     2161 ctctgtacaa ggaggaggaa gcggaactgg tttgagccaa gtcgaagctg gagcagttac
     2221 tatcggaaac tctgatgtat ttgcagaaga aagagacgga gttgatgctt caaaattagt
     2281 ggatcataaa gtagcagtgg tcgggatggc accaatcgtc aataaagata cagatgtcaa
     2341 agatatcacc aaacaggaat tgattgatat ctttacagga aaaatcacta actggaagga
     2401 agttggcggg aaagatcaaa aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg
     2461 cgcgacattc gaaaaatggg gactggatgg tgctacccct gtgcagtccc aagaacaaga
     2521 ttcatcagga acagttcggc agctggtaag tcaaacacca ggagcaatca gctatttagc
     2581 tttctcatat ctcgatgatt ccacacaagc actaagtatc gacggtgtag aaccaaaaga
     2641 agagaatgta gcagataaca gctggggaat ctggtcatat gaacatatgt acacgaacgg
     2701 aaaaccttcc cctgaagtcc aaaaattctt agactacatg atgacagaag aaatccaaga
     2761 aggacctgtc aaagaattgg gctatttacc aatcacaatg atggaagtag aacgtgatca
     2821 cgaaggaaat atcaaataac tagcagataa acatgccacg gtagtcgtta ctattaagga
     2881 aaaatcaact atgtttcccc acatatacat ttttccttta attgtgaaaa atagttcctc
     2941 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttattcga
     3001 aaaaaagagc tacgacatag aactgtcgta gctttttttt tgctatatga caggaatgaa
     3061 aggtgtttgc aagcttaatg tgaggaacac tttccatatc tgttctatac tggataggag
     3121 aagtttggaa atatccagaa aacgaaatca atcgaggtag ccacatgaag aataaatgga
     3181 taaatcgaag taaaaaaaag aaagtaacac aaagatcatc agataaagtc atccgtcttt
     3241 ttccatcgta taaagaagga ttaacggcag atcaagtcaa ggaacgaata gaaaaaggtg
     3301 cagcaaataa ttcagtcgat cccacattca aaacaaatca gcaaatcgta ttggaaaaca
     3361 tatttacgta tttcaatttg atctttctta tcttagccat tttgctttgt ttagtagaat
     3421 cctataagaa cttgactttt ttaccagtta tcatagccaa tacaggaatc gccatttttc
     3481 aggaaattcg atccaaaaag atcttggacg aactaaatgt tttaaataca gcaaaagtca
     3541 atgtcatacg agacgggata gaacaaacaa tagatataga agaccttgta atagatgaca
     3601 ttgttatttt agagactgga catcaaattc cagcagatgc agaggtcgtg gaagggaaac
     3661 tgcaagttaa tgaggcttta ttgacaggcg aagcagatga aataaccaaa gaaataggcg
     3721 atccattaat gtccggcagt ttcattgttt ccggaaaagc ttacgcccga ttagacaaag
     3781 ttggagcaga ttcgtatatt tcccagctga cagtcaaagc caagacaatg ggagaaggag
     3841 aacagtcgga gatgattgct tctcttaatc aattgatcaa atggattggg atcatcatta
     3901 ttcctatcgg tatcctgctt ttttctcaaa gttacttttt taatggaaac acgatcaaag
     3961 aaagtgtcgt tgcaatggaa gcagcattga tcggtatgat acctgaagga ctgtacttgc
     4021 tgacgacgat tgcattagca ttaagtgcga ctaaactagc aaagcaaaga gttcttttac
     4081 acaatatgaa aagcattgag acattggcaa gggtaaatgt cctttgtgta gataaaacag
     4141 gaacgatcac agaaaataaa atgtctgttc aaaaagtgat cgtctctaaa aaacaagaaa
     4201 taatcagtca gtcagatcaa ttggaagcat gcattgctga ctatgcaaaa gcgatggcag
     4261 gagacaatgc aacaatggaa gctgttaaag catattttac aaaaaccact gatcaatcct
     4321 atcaccatgt tattcctttt tcttctgtcc aaaaattcag cagtgtagcg ttggcagaca
     4381 aggtgtatgt tttaggagcg cccgaaatgg ttttgcgcga tcaattgccg gaatatgcgg
     4441 aagagtttgt ttctttcgct gaaaaaggct atcgcgtgtt ggtctttggt gtgtacgatg
     4501 ggattcttga agaaccagta ttgacagaag cagtcacacc attaggctat attctgattg
     4561 ctaatcctat cagaaaagaa gcaagagcca catttgatta cttcaaaaaa cagcaagtag
     4621 ccatcaaagt gatttctgga gataatccgc tcaccgtatc caatgtagct gtccaagcag
     4681 ggatttcaca tgctgatcag tacgttgatg catctaaatt atcagaagaa gaatatgaag
     4741 cagctgtcga aaaatataca gtttttggac gcgtcaagcc agaacaaaag aaaatcttcg
     4801 ttcaattgct aaagcgtcgt aacaatacag tagctatgac aggtgatggc gtgaatgata
     4861 ttctagccat gaaagaagca gactgcagta tagcgatggc ttccggaaat gaagccgcca
     4921 tgcaggcctc acaagtggtc ttacttgatt ctgacttttc acgcatgcca gaagttgttg
     4981 cagaaggacg gcgcgttgtg aacaatattg agcgatcagc cagcttgttt ttagtgaaga
     5041 atattttctc ctttttgctc tcactgtttt cagtgatctt tgctctgacc tatcctttag
     5101 aaccatcaca aatcacattg attagtttgt ttactatcgg acttccatct ttcttgcttg
     5161 ctctagaaga aaacaaaaag cgaatcagag ggaaattcat catgaatgtg atggaaaaag
     5221 ctgtgccagg tggactaaca gatatgatcg tagtcggtgc gttggtgatc tgcggggtga
     5281 ctttgaatct aaataaaaca gatgtttcta cagcatctac catgcttttg attgcagtag
     5341 ggttcctcgt tctctataaa atctgttcac cgctgaataa attcagaagt cagatcattc
     5401 ttttctgtgc tagcggtaac tttttttcgg tcatcttttt gcataagctg ttttcaatca
     5461 ccggtatctc agctgtatca cttttgctgt tgagcattct atttttctcg gcagattcga
     5521 tttttaggca tttgaccaca ttggtagaat atttgtttga acgtaaaaat gaaaaagagc
     5581 aaaagccgtt tagtcgcgta gttaaaaaat ttctatcgat atttaaacga gaaaattgac
     5641 gaaaagtatc tcaaaaaaga gtaaaaaaga acaaccactc gtgtatcttt cgaagcagga
     5701 tgagtcatcc aactttaaaa cgcacgagca gttgctcttt tttacatttt cggaatggta
     5761 acggtgaaag tcgaacctgt tccaagatga ctgtctacag taatcgtacc atgaaggagt
     5821 tgcacgtagt cttttacaat cgctaaccct aatccggtcc cgcctgaatg ccggcttcgc
     5881 gccttgtcta cgcggtaaaa acgctcaaag atccgttcct gatcctcaat gtcgatacct
     5941 ataccaaagt cttggacaga aaacgataga tcatctgttg cctgatagcg gataataatc
     6001 tcgctgtcgc tttttgaata ttggacagca ttttcaatca gatttttgat aattggataa
     6061 aggatatctg ttttagtagt aaatggttcg ttctttccaa tcaatcgaat cgtcaaccgt
     6121 ttcttttcga tgattggctg ataattttga acgatttgct ggaaataagg ttctgtataa
     6181 attgtctgga tctcgtaaga attctcgcca tcttttgaca gctggatgat ttcccgaatc
     6241 agtttatcta accggatcgc atctttttgc atgatctcaa gaaaagaagt cagagtttgc
     6301 gggtcatctt ttgcaccatc cagtaaagtc tcggtaaaac caatcagtga agtcacagga
     6361 gtttttaatt cgtgagagac gttgccaacg aaatcctttt gtagcttttc taaacgtcgc
     6421 actttcgtta agtcatacgc cacccctaga atctgtccgg taccttctga attagtaaag
     6481 tagcgcaaac tcaagtctaa tgtctgccga ccttctgtaa gggtgatctc ctgatggatc
     6541 agcggatgct caggagtcac ttgatgaatc agctgaatga gttttggctc ttgaatgact
     6601 tctgtgtacc gctgttcagg ttgatagctt accacgttta aatgtagctg catctttgga
     6661 ttaagcagta gtaaacgaga atcagcatca tcaatcagga atacgccaat catcagttcg
     6721 ttcagtaacg tatataattg ctcttctgtg gtagtatacg cccgatacat cttactcatt
     6781 tgttcgctca acgcattgat cgtctgatac aattcttccc attgatcggg tgtttgcatg
     6841 attacttccg cctgattagg attttgcacc atttttttta gtacgggcag cacggttttc
     6901 aatggctggt ttttttgata gatcagataa tagatcattc ctgcaagaac aaggaagaaa
     6961 gacagaaaga agaaaaagac ccaacggcga aaactctcag ttctcggtaa aaaaccgctt
     7021 gtcggttctg cgatacgtaa aatggcttct aactggccac tttttttgac tggtaatgcg
     7081 acatataaaa gatccccatt caaagtagta cttttgcgca aagcgctacc taggttccca
     7141 ccattcaata cggctttgat ttcgggacgg gagtttcgct gttcattcaa tgtttcattg
     7201 tttgtgtcaa ataagatctt tccagtagca tccattaaag taatccgttc gttcgactga
     7261 tggacgaatt cttccaaagc agttttgttt tgcgctgctt ggaggttttc gacatctaat
     7321 tgccggatca gcagttgtgc tttttttgtc aggtagcttt cttgctgttc cacgatctgc
     7381 tgttgaaaat aatgggaaat caattgccag ccaccaaaaa acaaactaac taaaagaata
     7441 agaaagaaga gacgttcata aatttttttc catttcatcg tttgggttcc tgaaacttat
     7501 agccaaatcc tctaatagtc accaagtact ttgggtgttt tggatctcgc tcgatttttt
     7561 ctcgcaaatg actaacgtgt acatctacga ttcggctttg tcctgcgaag tcaaaattcc
     7621 aaatgcggtc tagcaatgtg tctcggtcga tcacacggtc ttttcgtttc atgaaataaa
     7681 caagtaattc aaattctttc ggtgttagtt caatcagatg gtcgtctacg gtcacttgat
     7741 aattggtcaa atcagcagtg atttgtccaa tcgatagata ttcaggctca gcttcatctt
     7801 ttgattgctt acgaggttca attcgtctga atattgcttt catacgggct aatacttcgc
     7861 gaggactaaa tggtttggtc aaatagtcgt cagcacctat ttctaggcca atgatccgat
     7921 ccacttggtc atctttagcc gtcagcatca aaatcggtgt ttcatttttt tcttgacgca
     7981 gccgctgagt gatctccatg ccatccatcg ttggaagcat cacatctaaa atgatgaaat
     8041 caaatgattg ttctaatgct aattctaatc cttcgcctcc atctgtggca ctggttacct
     8101 tgtagccttc tttttccaaa ttgaacgtca agagcgttac aatagaaggt tcatcatcaa
     8161 caactagtat ttttttcatt caaatctcct ttaaataggt ttcattctgt ttatatttta
     8221 gcatagaatc agtacaaagg gctattttac aaaagaaata aatggtataa taggaaggca
     8281 ctttgctgaa tagaaaggaa gagcagtcaa tgattggaat cagtgcatgt ttaggcggtc
     8341 tggcctgtcg ctatgatgga cagaaaaaag aagtaccaga attgatggaa ctagttgaaa
     8401 ctggagaagc tgtcatggtc tgtccagaag tgatcggcgg attaccaatt cctagagatc
     8461 ccgctgaaat cattggtgga aatggattcg atgtgtggaa agatcaagca aaagtatgga
     8521 cgacaagcgg cgaagatgta acggaagcgt acaaaaatgg cgcgatcaaa gcctatcaaa
     8581 aattgcagga aaaacacatt gatctagtca tcatgaagga aaaaagccct tcatgcggaa
     8641 cccattcgat ttatgacggg agtttttccg gaataaaaaa aaatggtgcc ggagtggcta
     8701 ctgcttattt tattcagcaa aaaatgactg tgctctctga tgaagaatgg ctgaaaacta
     8761 gaggtgagca gaatggaaat cgaaaagacc aatcgaatga acgcgctctt tgaattttat
     8821 tcgaccttat tgacagaaaa acaaatgaac tacatggaat tatattatgc agatgatttt
     8881 tcattaggtg agatcgcgga agaatacgaa gtaagccgac aagcagtata tgacaatatc
     8941 aagcggacaa gcaagatctt ggaggattat gaaaaaaaac ttcatctttt ttctaattat
     9001 attgttcgag aacaggtatt ggaaaatatg actgcatata ttacagataa gtacccggaa
     9061 gataaaaaac tacttgaata tgtacagcaa attcaagcaa tcgaagaata aataaaagga
     9121 atgaagaaaa tatggcattt gaaagcttaa ctgaacgtct ccagcaggcg atgggaaaaa
     9181 taagaaaaaa aggaaaagta tcagaagctg acgtaaaaga aatgatgcgg gaaatccgcc
     9241 ttgccttact agaagccgat gttaacttgc aagtagtcaa agattttact aagcgcgtac
     9301 gcgaacgtgc ggtaggggca gaagtgctgg aaagtttatc acctgcacaa caaatcgtaa
     9361 aaatcgttga tgaagaattg acgatcacac ttggttctga aacagcagag ttaaataaat
     9421 caccaaaaat accaactgtt atcatgatgg ctggtcttca aggggcaggt aaaacgacct
     9481 ttactggtaa attagccaat tatttaaaga aaaatgaaaa tgctcgtccg ctcctaatcg
     9541 caggggacgt atatcgacca gctgcgatcg accaattgaa agtattaggt caacagctag
     9601 acgttcctgt atttgatatg ggaactgaag tcagcccggt agagatcgtc cgtcaaggga
     9661 tggagttagc aaaagaaaag aaaaacgact atgtattgat cgatacggca ggacgtctgc
     9721 atatcgatga aacattgatg gatgagttga aacaaatcaa agaattgacg caaccaaatg
     9781 agattttgct tgttgtcgat gccatgactg gtcaagatgc cgtcaacgta gctgatagct
     9841 tcaaccagca attaggtatt acaggggtcg tcatcactaa acttgatggg gatactcgag
     9901 gcggggcagc actatcgatc cgctcagtga caggcgcacc aatcaaattc atcggttctg
     9961 gtgaaaaatt gactgactta gaagtattcc acccagatcg tatggctagc cgtatccttg
    10021 gtatggggga tatgctgaca ttgattgaaa aagcgcagca agactatgac gagaaaaaag
    10081 cggaagaact tgcacagaaa atgcgggaaa attcattcga tttcaatgac tttattgaac
    10141 agcttgatca agtgatgggt atgggcccac tggaagatct aatcaaaatg atcccaggaa
    10201 tgaatcaagt ccctggaatc gaaaacgtca aggtagatcc aaaagatgtt gaacgcaaaa
    10261 aagcgatggt ttattctatg acgccagcag aaagagcaaa tcctgatctg ttgaacccaa
    10321 gccgtcgtcg ccgaattgct gccggttctg gaaacagtgt tgttgaagtg aatcgaatga
    10381 tcaaacaatt caaggaatca agaaaaatga tgcagcaaat gtccaaaggg gatatgaaca
    10441 tcccaggtat ggaccaaatg tttggttcag gcgtcaaagg aaaactaggc aaaatggcga
    10501 tgaatcgaat gatcaagaaa aataagaaga aaaagaaaaa acggaaataa gatgaaaaaa
    10561 acagcttcgg tacagactga aaatgtctac tgccggagct tttctatcag caatttttat
    10621 tctttactaa tacaattact ctaaacgaag aggtggcaca gatgagatgt ccgtggagtg
    10681 aacaaacaga aagtatgcgg caatatcatg atactgtctg gggtgttcct gaatatgatg
    10741 accaaaagct gttccgaaaa ttgatgcttg atattaatca agccggattg agctggcaga
    10801 cgattttaaa taaaagtgaa gcattcgatg aagcatatga tcgattcgat attaaaaaag
    10861 tcgcaaatta tggagaaaca aaaatcagtg aactaatgga aaacaaagga attattcgta
    10921 accgaagaaa aatcgaagca gccgtccaaa acgccaaagc agtcttgaaa attcaagaag
    10981 aaatcggcag tttttcagag tatctttggt cgttttctaa tggaaaaatc gttgattctt
    11041 cttatcattc acaagaagaa gtcccaacaa caagtcctct ttcagatgaa ttagcaaaag
    11101 atctaaagaa aagaggattt aaatttatcg gaagcacaac aatctatgct tttttagaag
    11161 ctgtcgggat catcaatgat caccttgaca gttgtttccg caaagaagag gtcgtacgta
    11221 tcggcagaaa gggcgaataa agcatgcgaa aaatcatatt ttatggtgct ataagtttag
    11281 atggctattt ggcaacgaaa acggatgatc ttcaatggct ttttgacact ccaacaggta
    11341 agcaaaccac ttatgaagct ttttatgaaa caatcgatac gaccatcatg ggcagaaaaa
    11401 cttatcagga agcaaaaaaa tatttggaga ccgaagcaat ttatccagag aaaaagaatt
    11461 tcgttttttc cacccacgca caattacaat tgccagatgc tgaggtcgta aacgaagatc
    11521 ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa agatatctgg gttgtgggtg
    11581 gcggtcgatt gatcaaaccg ctattggaac atcaaatgat tgatgaatgg tatatccaga
    11641 ttacccctgt attattaggg gacgggattc ctttattcca aaaaggaaca tatgaagcgc
    11701 gttttgaaat gctagacacg acacgattcg gtgaatttat cgaattgcat tatgtacgaa
    11761 agtagaagta aataaaataa aaaaggcaac tatatgcaga aatgtcctgt acatagttgc
    11821 cttttttatt accgttatgc tttttactct gttaatttgt tagaaaaatc tagatacgca
    11881 tctaaaatcg tttggaagaa acttaatgtt ccttcaacga tattaccatt ttcatcaatt
    11941 agattcgcaa cgtttccgat atatgcttcc ggttgctgca aggttggcac attcaaaaag
    12001 acaagtgatt gtcgtagatg gtggtttgcg ccaaagccgc cgatcccacc tggtgatgca
    12061 gtaacgacta aacctggttt atgatcccaa acactgtgtc cataaggtct tgagcctaca
    12121 tctaaagcat ttttcaatac tgctggcaca gaacggttgt attcaggagt aacgaaaacg
    12181 acaccgtcta gtcccctcac ttcctcacga aaacgagtcc attcagcagg agcctgttct
    12241 ggagtttcga gatcctcatt gtaaaatggc agatcatcga tttttacaaa tacactttcg
    12301 tacccttcag gaagcaattt cgcaaaagct tctgctactt ttttgttgta agaatctttt
    12361 cttaaactac caataaaaaa tccaattttt tttgtcatac gatttttcct ccttcaaact
    12421 atctataaca atcttacaaa aaataagtaa ctggagcaaa taaaaacact tactgacaaa
    12481 agctacatag aagatagatt acttattttt aacaaaaaag aagtctaaaa tcttctattt
    12541 cctaaaaaaa atcgaattta atcaagctgt aaagaaaaaa agctttacag ggtaaaaaaa
    12601 aactgttaca ctacatcttg tgaataaaac aatggaggtg gaaataaata atggcagtta
    12661 aaatccgttt aaaacgtatg ggttctaaaa agagtccgtt ttaccgtatc gtcgtagctg
    12721 attcacgttc tcctcgtgat ggacgtttca tcgaaactgt aggtacttac aatcctttga
    12781 aagaccctgc agaagtagtt ttaaaagaag acttagttct tgactggtta tcaaaaggtg
    12841 cacaaccttc tgacactgta cgtaacatcc tttcaaaaga aggcgttatg caaaaacacc
    12901 acgaagctaa attctcaaag aaataaggtg accggatatg aaagatttaa gcgacttagt
    12961 cttaacaatc gttcgtccgc tagtcactta tcctgatcaa gtcaagttag acgtcgtaga
    13021 gtcgaaagac ttttacgagt acaatctaac agtggctcct gaagatattg gccgtatcat
    13081 tggaaaacaa gggcgtgttg ctaaagcaat ccgcacaatc gtttacggtg ttcggatcaa
    13141 tgcaccgaaa aaagtgcgtt tgaatatcat cgatgataag gaaaagtaaa taaacgtgct
    13201 gtactcgaat tttcgagtgc agcttttttg tttttttatt aattgaagaa atgattattt
    13261 ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg agtgaacagc caatgagaaa
    13321 gaaaatgtta tttattccat ttgctctatt gttaagcgct tgtagttcgg ttactcaaga
    13381 atcagacaat acacatctat caagcagtat atctgaaact gttaccagtc cagaaaaaag
    13441 tagtaccaaa acggctacca ccactgaaca aacaatggct acctcaaata atgagaaaaa
    13501 gactgcttta gaccagttga aagaacaaca gccaaatgtt cccatgcctc tagatgtacc
    13561 agtctcttca ggctatctca atatcgcagc gacacataca aagcaaggtt attctatttt
    13621 atattacaga acagatcgtc ccctcgggtt gaatgctgac gaattgaatc aagaaacgcc
    13681 tattgcaacc tatctatatc aatatgggtt tgcttctagt caagaaacaa tccaagtttt
    13741 gcagcccttt gagatcgaca caaatggtca gcaagtggac ttaggttctc gaatcacagg
    13801 gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg caagaaggaa actggcgtat
    13861 tcgaatccgt gggaataata tagaaggcca agatccctta ctattagcta aagaaatcgt
    13921 agcttatttg gaagaaaaca gtctaccagc acctgaacaa tttggtaaaa ttactgttga
    13981 tatgggtgat acgacgaatc gagccgtaga agtaagctgg caagaaccga aaaatgccta
    14041 tacgatcact catcaagatc ctatgtctgc gttgaagatg gcagtttcta tgaagaggtt
    14101 gtgaaatcag cgcgctgatc tgagcccatc atttaactcc aagtcacagg aagtaatcaa
    14161 aaatagcacg ccgcattttt gcataatttt ggcttaatac cttaaaagaa aactagaatt
    14221 gcctcttcac acatgctaaa ataaaacaga caaaaaagaa atggggatat aagttgactg
    14281 aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat caaaggcgaa gtccgtgtta
    14341 tctcaacaac ggatttccca gaagaacgtt acaaaaaagg aacggtgtta acactattcc
    14401 aagacggaaa agcacctgtg gaattaacag tcaaaagtca tcgcaaacat aaaaattttg
    14461 acttattgag ttttgaagga catccttcta tcaatgatgt ggaaaaatat cgggatggca
    14521 tattaaaagt gtcaaaagac aactctgtag atctagctga aaatgaattc tattaccatg
    14581 agatcatcgg tctgcatgta ttagaagatg gaactgagtt aggtaaagta aaagaaatct
    14641 tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc gaaaaaagct gatatattgc
    14701 ttccatatat cgcttctgtc gtcaaagaag tcgatttaga agctggagtg gtccgtgtag
    14761 aaattccaga aggactgatt gacgatgaag attgatgtat tgactttatt tccaagaatg
    14821 tttgaaggtc ctatggggga atccatcatc ggtaaggctg tagataaagg attattagat
    14881 atcaatatct ctaacttccg cgattattca gataacaaac atcagacagt agatgattat
    14941 ccatacggcg gtggagcagg tatgctgctc aaagtccagc ccatctatga taacatccaa
    15001 gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa ttcttcttga cccagctggt
    15061 aaacgattcg atcagaaaat ggcagaagaa ttttcacaag aagaacactt agtattcatt
    15121 tgtggtcatt atgagggata tgatgaacgt atccgcacat tagtgacaga tgaagtttcc
    15181 ttaggagatt atgtccttac tgggggagaa ttaggtgcga tggtcatgat cgatgcaaca
    15241 gttcggcttt tgccagatgt gttagggaat cagacttcag ctcaaacgga ttcttattca
    15301 accggtttat tggaacatcc ccaatatact cgcccggcag aatataaagg gatgaaagta
    15361 ccagaagtat tgacaaatgg aaatcataaa ttgattgaag aatggcaatt aaaagaatca
    15421 ctaagaagga cctatcaacg tcggcctgat cttttggaaa cacttgaatg gacacctcaa
    15481 atgacgaaat ttttagaaga aatcaagaaa gaagaacaag aaaaaacagc agatgaagcc
    15541 aagtgacttt ttctaaaata ttctttacag taggttgata atatgttagt attttatggt
    15601 gagtgcaaaa gcacttaact attacgatat tccgctatga gaaaagctca taagaatatt
    15661 tggaataagg agaagaaaac catgaatcca ttaatcgaag aattaacaaa agaacaatta
    15721 cgttctgaca tcccagcgtt ccgccctggt gacactgtgc gtgttcacgc aaaagttgtt
    15781 gaaggtactc gtgaacgtat ccagttattt gaaggtgttg ttatcaaacg ccgcggtgct
    15841 ggaatcagcg aaacttatac agtacgtaaa gtttctaacg gagtgggcgt tgaacgtaca
    15901 ttcccattgc atacaccacg tgttgcaaaa atcgaagtag ttcgctacgg taaagtacgt
    15961 cgtgcaaaat tgtactacct acgtgcatta cacggaaaag ctgctcgtat caaagaaatc
    16021 cgtcgttaat cattgttatc agactgagaa agaacccttg gtattcaagg gttctttttt
    16081 tattatctgt ttttttatat taacgatttc tatttggtac atttttgatt aataaaaagg
    16141 ggcaaaaaag gggcaacaag ttacagtttt tctatatctt ctttcaattt ttcttttact
    16201 ccttttgtca catgcaaata aatcttttca gtgatatcac tattttcgtg cccaacgcga
    16261 tcctgaatag catacagagg agttcctagt tccgctaatt ttgaaatatg ggtatgtcta
    16321 aaaatatgtg aactaagttt tttatcaatc ttcatgtcag ctttatgatt tctcaaatag
    16381 gtgttaattg ctgttagttg gaaaggagtt cctttcgttg tttgaaatag aaattgaccc
    16441 ttcggattta attctagaag ctcattgtaa atagctatcg ctttttttgg taaatcaatt
    16501 tctcgcattc cagcagcagt ttttgtagaa tcagattttt tcatatcagc tattgaacgt
    16561 tctctataca tcatcgtccc atttataact actgatgcat tattattggt aatgtgtaca
    16621 tcgtctttac ttaatgcgat tgcttctcca ggtctcattc cagtcaaata tagccactgg
    16681 aaaaggagag aatatctttt attgtgtgaa gttgtgaaat ctactagtct tttatattca
    16741 tcatcttcta aaaacttatc tttaattttt atcgtttttg actctcgttt ataatcaata
    16801 actacttcgt tgataggatt tttttctaca tagccttttt tcatagcgta tgaaaaaaga
    16861 agattcaatt tggatttaat tacactgacg tacttatttg acaagtcatc tttatatatc
    16921 atatcttcaa aaatattatt taaatctact gtattaatac cagaaacgat gtaagtctca
    16981 ggcatcttct tctttatagt gtttaagata ttattcgtag gataatatgt agactcctta
    17041 acttgccttt tgtaaataac taaccattct tcgacaagct catgaaatgt tagattaggc
    17101 ttctggagtg ttttttcatt tagttttata tcaatttttt tatttaactc cagtaatgcc
    17161 actttctgag tttctcgaga cttattttta taagtaatgc tcactttttt tctttttcta
    17221 gtttttggat caatatatcg ttcattatat ttatatactt tttttccgtt tttatcagtt
    17281 ttggtttcaa tccacattgt tttcatctcc tatttgttgc tataatagga atggataagt
    17341 aagccgatta tagcaggttt atttttcatc acgtccacaa actttggcga gggagggggc
    17401 gtgtttttgt attttaacga tttatattga atgttgattc agcactttca gcaactgtac
    17461 tataatcaga cggattatat aacactccgg tttttatcgt tacttttgta atatcgttaa
    17521 ctttagatgg atctaagtaa gctaaactat aaaattcttt actttcagtt tttttgaaaa
    17581 acgagtttgt tgtcattgta tgcataagat cgtctgaact gaaatcaatt tgttggccgt
    17641 tatcaagtat ggcgtgtgca agcccattat aaccataatc tacttcagaa ttgtttttaa
    17701 ctttgaatgc aatttgtaaa ccataaaaat ttccttcact atctttgtga ttatttgcat
    17761 cgtagtaacc agcagcgcta gggtcagcat aattggaata cttgagtagt ttgatattag
    17821 atatataaat gccgatatca ccaagaggaa tatctgattg tgggcttgcc gttccaatta
    17881 attcaatttt gccacttgta tctctttttt ctttggtcca ttgaccaact ttgaggaggg
    17941 ggccatcaac ctcctgtgaa tttttagaag actgtgttgt actttctgat aacgtaactg
    18001 aagagtcttt ttcgtttgtt ttgccagtat tatctacaac attagattgg ctacatccgg
    18061 taagaaaaaa agcaccaaat actaacccta aaatcacttt tttcattctt tattctccgt
    18121 ttctatgata ttatttttat gtaggatctt agaaacgaga tcttagtccg tgttgcagca
    18181 cgggcttttt tctttataac ttttttagag attataggca aaatagtagg acacaaaaat
    18241 atattattgt attccgtatt tagaaaatcc taattgaact tcaccagaag ttttttgctg
    18301 tgttgtacgc aatgcttctt cttcagacat tccattctgt actttccatg caacaggcga
    18361 catcccgtat ttgttaacaa aatcagtaag tgataaagtg tcagcgtctt gctgaccgct
    18421 tgtttgttgg tcttctggat tttgttgaga tgctgcttgt tgttctttct gatcttgact
    18481 gataatattg ccagcatcat ctgtagtcaa tccattttca taaagggcca cgccgaaagc
    18541 ttcccactct ttgttggacc aatttgcacg atcagctgga gttgactgta aagtgcgttg
    18601 tttcatctgt tcatatgttt cttcttgagg tgcggtttgg attgtatcct gactggagct
    18661 tataactgtt gggctaggtt ccgccgtagc ttggttagag cttgtaactg ttgaactaga
    18721 atctgtctta gatgtagatt tgctagtaga ggaactggtt tcagttgttt cttttgtttt
    18781 acttactttt gtttcttggt tagaagtggc atctgttgat tcagcttttt tattatttga
    18841 acaagctgaa agtagcagag cagtacttaa caacaacata acgctaactt ttttcatttt
    18901 ataattcctc tttctcgttg taatatgtgt gctaacacgg gcttttttat ataagaaaac
    18961 gataagcgct ttctggaagt ccgtaaagat tctttaattc atcgattttt ttgggatatt
    19021 gatcattatc ttctttataa agagaaacaa tgagattagc agcaaagcaa ttagcttcgc
    19081 tttcagattt gcttctagat gttcttgttg atacatagta actggataag ccgcgatgaa
    19141 aaatagcgtg acctaattcg tgagcgcaaa tgtagaatct ttcctcagag tctcgcagtt
    19201 catcatttaa gaagattatt gcacgacctc taatttcttg aaactgtcct ttgggatttt
    19261 cgataaaagg aacgtattga attttaatgc ccatcttttc acaaatataa aaaggattag
    19321 cagaccggta tttccgcttc aactcctcga ctaaattaat cgtatccatc tccataagct
    19381 cacatctttt tgcctttttc tttgtcttct ttcacaatat cccagaaggt tccaataagg
    19441 atatctttta cgcgttggac ctgttcaggc gtcagtgttt ctccgccata agacatattg
    19501 acatttgaat ctagtaattt atcaagttca actacttcat cttttgttgc ccagtcagga
    19561 acttggtttc taccgagtaa ataatcagta gttacattaa aataatctgc tacaagttgt
    19621 agtcttttag tactaggagt tctatttttc cattgataaa tcgtgttttt aggtatattt
    19681 aattcttctt ccaattgagt tatacttatg cctcttt
//
LOCUS       DAFKHN010000051        18026 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFKHN010000051 DAFKHN010000000
VERSION     DAFKHN010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.051"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(49..1515)
                     /locus_tag="LY912_001835"
     CDS             complement(49..1515)
                     /locus_tag="LY912_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBM6955513.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1902..2498
                     /locus_tag="LY912_001836"
     CDS             1902..2498
                     /locus_tag="LY912_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBM6955514.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2556..3038)
                     /locus_tag="LY912_001837"
     CDS             complement(2556..3038)
                     /locus_tag="LY912_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955515.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3144..3341)
                     /locus_tag="LY912_001838"
     CDS             complement(3144..3341)
                     /locus_tag="LY912_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955516.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3636..4394
                     /locus_tag="LY912_001839"
     CDS             3636..4394
                     /locus_tag="LY912_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBM6955517.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4454..4882
                     /locus_tag="LY912_001840"
     CDS             4454..4882
                     /locus_tag="LY912_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955518.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4928..5000
                     /locus_tag="LY912_001841"
     tRNA            4928..5000
                     /locus_tag="LY912_001841"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4961..4963,aa:Gln,seq:ctg)
     gene            complement(5150..5521)
                     /locus_tag="LY912_001842"
     CDS             complement(5150..5521)
                     /locus_tag="LY912_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBM6955519.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5736..5921
                     /locus_tag="LY912_001843"
     CDS             5736..5921
                     /locus_tag="LY912_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955520.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6004..6192)
                     /locus_tag="LY912_001844"
     CDS             complement(6004..6192)
                     /locus_tag="LY912_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955521.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6216..6479)
                     /locus_tag="LY912_001845"
     CDS             complement(6216..6479)
                     /locus_tag="LY912_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955522.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6637..6894
                     /locus_tag="LY912_001846"
     CDS             6637..6894
                     /locus_tag="LY912_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBM6955523.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6965..7156)
                     /locus_tag="LY912_001847"
     CDS             complement(6965..7156)
                     /locus_tag="LY912_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955524.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7297..7617)
                     /locus_tag="LY912_001848"
     CDS             complement(7297..7617)
                     /locus_tag="LY912_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955525.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7640..8074)
                     /locus_tag="LY912_001849"
     CDS             complement(7640..8074)
                     /locus_tag="LY912_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBM6955526.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8409..9047
                     /locus_tag="LY912_001850"
     CDS             8409..9047
                     /locus_tag="LY912_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBM6955527.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9371..9454)
                     /locus_tag="LY912_001851"
     tRNA            complement(9371..9454)
                     /locus_tag="LY912_001851"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9418..9420),aa:Leu,seq:cag)
     gene            9982..10428
                     /locus_tag="LY912_001852"
     CDS             9982..10428
                     /locus_tag="LY912_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955528.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNLNCQIKLDRSSILT"
     gene            complement(10392..11351)
                     /locus_tag="LY912_001853"
     CDS             complement(10392..11351)
                     /locus_tag="LY912_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBM6955529.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            11446..11547
                     /locus_tag="LY912_001854"
                     /pseudo
     CDS             11446..11547
                     /locus_tag="LY912_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(11737..12081)
                     /locus_tag="LY912_001855"
     CDS             complement(11737..12081)
                     /locus_tag="LY912_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBM6955530.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(12235..13155)
                     /locus_tag="LY912_001856"
     CDS             complement(12235..13155)
                     /locus_tag="LY912_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBM6955531.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            13342..13833
                     /locus_tag="LY912_001857"
     CDS             13342..13833
                     /locus_tag="LY912_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBM6955532.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(13857..16232)
                     /locus_tag="LY912_001858"
     CDS             complement(13857..16232)
                     /locus_tag="LY912_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBM6955533.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            16558..17184
                     /locus_tag="LY912_001859"
     CDS             16558..17184
                     /locus_tag="LY912_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBM6955534.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            17207..17911
                     /locus_tag="LY912_001860"
     CDS             17207..17911
                     /locus_tag="LY912_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBM6955535.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
BASE COUNT         5621 a         3517 c         3011 g         5877 t
ORIGIN      
        1 aaacaggaac tgctgcaaat aagcaattcc tgtttttatg ttcattgatt aatgaataga
       61 gcccattagt tttttgattg gttctttcac agtaaatagc aagataccac cgacgattgc
      121 tactgcaccg ataataccga agtaagcaga ttctgttccc ggtgtgtaga agcgtgcaat
      181 ttgtgcattg attgcttgtg aagaagcatc agctaagaac caaatagcga ttgtttgtga
      241 ttcaaatgct cgtggtgcta attttgttgt cacagacaaa ccaactggtg aaagacacaa
      301 ttcagcaata accacgatga agaaacttcc caacaaccac aatggactta cttttccact
      361 tgtaccataa agcatacccg gcaacatcaa tagcaagtac gataatcctg caaataaaag
      421 tccaagagag aatttcacta ctgtagatgg ttgacgttca ccaagtttcg tccacatcgt
      481 tacgaatact ggtgtcagaa taaagatgaa aattggattc aatgattgat accagcttgc
      541 ttggatcgtt acaccaaata gcgtagattg tgtacgttca ctagcaaata aagctaagat
      601 agatgaacct tgttcttgta atgaccagaa aatgattgct gcaaggaata atgggatata
      661 agcccatact cttggttttt cttcagcagt tacatctttt gaagtcagca ttttgataaa
      721 gtaatacaac ggtaagataa tccccaatac actgattgta ttgacaaaaa agtcaattgt
      781 cagatgacca gttagttgtg ccccgccgaa tactgcagcg ataacaacaa gtgcgatgat
      841 caagttacgg atgaatcctt tacgttcttc agttgtcaaa ggattcggcg gtgttgtacc
      901 cactccgtct aatgtcttgc gtccttggat gatgtattgt aataatccaa agaacatccc
      961 aatagcagct aaagagaacc ctaaatgata gttatattct tgaccgattg taccaacgat
     1021 tagtggtgct aataatgccc ctaagttgac acccatgtaa aaaatcgaaa atcctgcatc
     1081 tcttcgcaag tcagtctttg aataaagatg tccgaccatg ccagaaacat ttggtttcaa
     1141 aaaggcggtt ccgataataa tcaatgccat cgaaacaaac aatgtactta caccaaatgg
     1201 taaagccaag acgatgtggc caagcataat gaaaactcca ccgaagaata cagtgcgttt
     1261 tgctcctaac actcggtcag atacccatcc gccgacgata ctagacatgt agatcaaaga
     1321 tccgtagatc gacatgatag ctaatgctgt tgctcgtggt aatccaagtc ccccgttggc
     1381 aactgtatcg tacatataat agataagtaa tgcacgcata ccgtaataac taaatcgttc
     1441 ccacatctca gtgaagaaca aagttgacaa tcccttcggc tgcccgaaga agcccttgtc
     1501 ttgctgtttt tccataatct ataccccaat tctttaaatt ttcagaaaat attatacatc
     1561 tttaccgaaa aatttaacta aaaaacttat ttaagaaata taaactaatt ttctataaaa
     1621 gcaagtaatt tttaatggca atatcataaa aaaaagaaga tagagattta ataattatat
     1681 atcagctgtt tttttcaaat aagcaaaaat tcctaaaaca caacaatgaa agcgataact
     1741 aagaaaatcc ttacataacg atttttctta ttaaaattgt tttttgaact tcgcttattt
     1801 tttgtgagca tatctgttta cttacttttt gtaaggtgct atacttcatt tcgtaatcaa
     1861 ttaaaaaaat gcaaaacgca aatcaaagga gaaattttat tatgacaact tttactgaca
     1921 ctttgaaaaa ccgccgttca atctatcatc taggacgtaa tgtttcactt tctaatgaag
     1981 aattaacaac tttgatcaaa gaagcaatta aagaaagccc aactgctttc aatgctcaat
     2041 caacacgcgc agttatcctt ttcggagatg cacatgaaaa actttgggaa atcactgaag
     2101 aagcacttcg cccattgact ccagcagaag ctttcccaaa tacacaaaac aaattagctg
     2161 gtttcaaaaa tggttatggt acagtattat tcttcaaaga tactgacgtg gtaaaaggtc
     2221 tacaagaaca atttgaatta tatgcagaca acttcccaga ttggtcagaa caatcaaacg
     2281 gaatcgcaac agctaatact tgggtagcat tagttgataa aggattgggc gcaaacttgc
     2341 aacattacaa cccagttatt gacgaagcag ttgcaaaaga atggaatatc ccttcaaact
     2401 ggaaactacg ttcgcaatta gtattcggtt caccagaaac accggctggg gaaaaagaat
     2461 acatgaacga tgccgatcgc ttccgcgtat ttggataatt ttatttgaaa taaaaaacag
     2521 aggttgtgac aaacatcttg tcgcaacctc tgtttttatt ctggatcaat cataatatca
     2581 atctctgcct catcgtttaa gcgttgggac aaaaatggaa ctaattcttc taatgatgca
     2641 gaaaatttca gcatcggtcc tcgccatccg tttcggaaaa aattcatttt tacgatttta
     2701 gaaccttttg gctgatataa tacaatttta ttgatctcag aaaaaggaac accttttttg
     2761 tcaaagctat tcaaaacaag tccttcttct gtgattcctc tactgtccaa caaaaaacta
     2821 ataaaaatca ttgctgacaa gatccctttt gccaattcat ctgctgtagg atgactgatg
     2881 agtgtatacc aaatgactag tgacactaag aagggtatca ccaagtagac ccatcgattt
     2941 cgcacagtcc gataaataat ttcttttcga accagccaaa gaaataaaaa catcacaaca
     3001 acgaataaaa acaatagaac cgtaaagaat gttaccatga caactcgcct cgctttttct
     3061 tctccagaaa ataggaaaag aatactgatt taccttctca aagaaattgg acttgcagca
     3121 cgccgcacgt ccaattgttt tctttattca aatgtatcat attttgcaac aaccatgctt
     3181 gctttttcat ctaataattc ttggtcctct gcagcacatt gggcaacttt gaccacggcg
     3241 cagtttgtca tttttgatac aacttcacca atgaccgttt ttgtaaaacc aattggtttg
     3301 catgcatatt gttctcctaa attaatcatt tcttccgtca tcaaaatcct cctaaactgc
     3361 tggaactttt ctccacatta ccactgctat ttctttggag atttaactca ttgattttta
     3421 tttacagtta aaaatcaacc ttacaggcat tatagcgtac tgttttcgtt ttcacaatta
     3481 aaacagctgt tgtatttaga agaatttttt tcaaaaaatt aaaacatatt ccttaaaaac
     3541 taattatttc ctacatatta aaatataata cttccatttc caataaaaat acatttataa
     3601 taggaaagat aaacagctga aaagggagat ttcaaatgaa gaaaaaaacg ttcaaaaaac
     3661 tattgtttct agggggcaca gctgctcttt tattaagcgg tacaagttat tacctacata
     3721 tccattctcc agaacataca atgaacactg cacaaaaaag ttcaacacaa aaaacgaaaa
     3781 agacaaaaga gaaagcagaa gttttactag atgttccatt agagagccag tttgattctc
     3841 cttctttaga aaatggctgt gaagtcactt cgctttctat gcttttatct ttttatggtt
     3901 atgaaacaac taaaaaccag ttagctgagc aattggatta cgtccctgtt ttcaatgcag
     3961 atgggactca tggcgatcct aatgaaggat ttgttggtga tatcagtggc ggagactggg
     4021 ctatggtcgt ctatgttccc ccagttgcct cccttgctca gcaaatcgtc caaacggatt
     4081 atcacacttt tccaaaaacc gatgctcaac tcgatgatat caaaaaagca ctatctaaag
     4141 gaaatcctgt ctggacttct gtgactatca attttgaagt cccagatgaa actgatttta
     4201 tgacttggac cacaaataat ggagaagtaa gagtcactcc tcttgttcat gcttgtgtag
     4261 tcactggata tgacaaagaa aatatttatg tcaacgatcc ctatggtgta aaaaatcgag
     4321 cagtaccgat caacgatttt tcggcgattt tcactgcaat gggtggacag atgctaactt
     4381 tggagaaaag ctagtaattc aaacaaaaat cccttatact caagatacca aacctttgaa
     4441 gggagcgtag ataatggaaa aattcacaca taaaaaaatg gatccaaatg aaattccgat
     4501 tatttttgtc cgtgactgca agggaaatgt tcaaggtaaa gtctctatta atgagtggaa
     4561 cgagcgtcgc agacctgcta ccctcaatga actggaaatc aaattgtatc gtcaatctct
     4621 tgtttattac gcagatcaag agtacgagaa agccaccgat ttattgaaat ttctaattgc
     4681 tcgaacagag tatactcgct ttgaatatat tgaacgttta gcaaacatct atcatattat
     4741 gaatgaacct gtcaaagaat atcagttatt ggacaccgtc ttgtcagtag cagaactgat
     4801 tgcccttcct gctggattag aaaagaaact agtacgccgc cttttacgag taaagcaaca
     4861 actatccgat caagaaaaat aacttgcgtt tttttaggaa agtgctatga ttattttgtt
     4921 gaataaatgg gatgtagcca aactggtaag gcacttgact ctgaatcaag caattgtagg
     4981 ttcgaaccct gccatcccaa tttgatgtgc ttgctgaaaa aatgaacccc ctgtaaaaga
     5041 acaatctttt tgcaggggga ttattgtatt atttttacta cttgtattta gtttacataa
     5101 ttaaattatg aataataaaa tcgggcgtat tcttaataca aaaactgatt tacccaataa
     5161 ttgctaatgc tttctccgga actttttctc taggaacttc ctcatacgtt tctatgtgtg
     5221 ctcctttatt gctaattttc aaataatgat tttcttttaa cacagaaaga ccattaaatt
     5281 caaccgttcg ttctttccca ttggcatcag cagctttctg cacatacctt gctgtaccat
     5341 attcatttac ttcctctggt ttttgtgtct ttacatagac ctctcctttt tcaactaatg
     5401 gatttagctg atcaagtata ccagggattt ctccataact tccttcagta taatatttca
     5461 gtccaaatag caaaatacca ctaatcgccg ccagtccaat caaatattta atcactttca
     5521 tctttctacc tccttgttat atattcagta tatgggtcag ttaaagaaat tccatccgtc
     5581 ccaagttgga gatttttctc ctactttaga agcgagaatc gagtgttttt ttagtaaaaa
     5641 tgatcgttat ttgatattat tgacgtgtgg ataaatcagt ttttctcgtt ttgtccatgt
     5701 aaaaaatcat gttgatagca aaggatgtgt tcaaaatgaa tcaagaagaa ttatttcaaa
     5761 aagtcaagga aatgattaag aacggcaatt tcgatggcgc aaaacgattt atcgaagaac
     5821 ataaagaaca attaggacct tataaagaga aagcccaaaa tcttttaaaa gatgtaaata
     5881 tcgacagtgt caaaaacaaa tttaaaaatc tattcaaata agtaaaactt tcacttttgt
     5941 aaaatcaaag gaggacaatg ctgctgcatc gtcctccttt ggttcttttc tgaatacttc
     6001 atactaaaat aaacgtgtcg gatcgtaatg ataagtcaca ttgccgttca gtgaggcttt
     6061 tcccaccaca tatttacgat tctccaactt cagccacgct tctcgaaaag ccattaattc
     6121 ttctcttttt acatcaatct tttcgatttt tccatcgatc aaatcttgaa taagttgttc
     6181 atatggattc atttttttcc tccatctgct gtcaatcaat aagttgtaaa aataggttca
     6241 tatgcttttt tggtatctag atcttctctg actttgactg tcgtataaat aattttttct
     6301 actgggatac tataataact tccttcacca ttattgaatc ggtgaacgtc tttctttgct
     6361 aaaataccat ttattttatt cgtcagtaca cgttgttcga cactgttact tacaacatag
     6421 taaatcaccc gaatattatt gatcaaatgc aaatcgattt ctaacactac atgatccatg
     6481 aaaatcccac tccttctttc actttgatta tagcaagttt ctcctctaat ttcaaaatcg
     6541 atacagattt taccggataa atccacaaaa ctgcttgcgc catttcgcac aaagtgttat
     6601 tttgtatcat ggactttatt tatcggaggc aatagtatga tcgcgatcgg tcaatttgtt
     6661 ttttatattc ctttttttat tatgataagc attcttttct attacataaa atggacaaaa
     6721 aagaagtttt cagttttact ggcctcttta cctgctgtat attttactta tcaaattttt
     6781 tcttttaggc attgggaaac aacgtctgta ttaataacac acatcatcga attgacgctt
     6841 tcagtaattt ttcttattat ttggatctat tttttatata agaatcagaa ttgaatccct
     6901 cgcatgttta aaaagaaaac gattaaagat gcagcaaatt tctgccgatc tttaatcgtt
     6961 ttttctattc tgttatacca aaaaaatgtt tgaatcggtg aaggatcgtt ccttgtttta
     7021 attctataaa ttcttgtgcg atcgggtact tttcttccaa attttctttg ttcttttcga
     7081 tcaggctttt cgcttcttca tattttttat ctgcacatag tgcttttact tcctgtaata
     7141 cttttcctgc ttccatttgc ctcaccctct tgccatttta ttgctttaag ttttatttaa
     7201 gttatacgca ttattctagt ttcatcccaa ataacctttt ttcattttta ctcctcgaac
     7261 taatcagttt tctaaaggct gattggttcg tcttttttat ttttcctcca tttcattctg
     7321 ctcttctgtt aatttatcta atgctttgat tgatgctgcg gctcttgcat aatcatagct
     7381 gtataattcc ataaatttat caggcagaac aaaccacgct ggatgataac cgttagctgt
     7441 gacagggaat cctttatctt gttggttatc tccatcccat ctcagagcaa cacctttttt
     7501 tcctttccac tttactaaag cgatcgagta tcccttcttt gtttgtgtgc cgtcttcaat
     7561 aattgctaaa atttctattt tttcttttgg cgcacggact tcttgaggac gaaccatttt
     7621 ctattcctcc cttatctcat tacttcacga ccaacacact gcaaggggca tgtgatacga
     7681 cataagaagc ggtcgatcca actaatgctt gttgtatagc accttttcct gtcgctccca
     7741 taacgatcaa atcaatattt tcttgtccag ggatgacatt ggcaatcaaa tttcttggat
     7801 ctccagtttc aactattgcg tggatctcag caatgccgta ctctttggca tcattgattt
     7861 ttttcagcat ggctacttct gttctttgtt tttcatctgc atagattttt gaaaaggcat
     7921 aggcactatg ggtcagctca actttgttga tgattgacac gataaataag tgggcttcat
     7981 tgtcctttgc taagtcaagg gcttcagcga acgctttgat cgattgtctt gatccgtcaa
     8041 ctgctaccat gatgttctgg tatcttttac tcattggaac cgcctccttt ttcttttatt
     8101 gtaacatctc aagcaaaaat acaaaaaata tacgcaatat gtaaataaaa tgatgaacaa
     8161 aagcaatttc tttcaagtta tttatacatt tcttttctca tcagaacacc tgttctaatc
     8221 ccattatttc tgcattatgt gaaattcctc atcatttttc acatcgagcg aacatcattc
     8281 tgttacaaaa aacgtggatt tgtcataaat tgtcatgctt cttttaccta tgaaatattt
     8341 tcacgtgtta aagtattcct cgttgaacac aacaaataaa actttttaac gaataaagga
     8401 gatttttcat gacatcactt aaaactttac tttttggaac aactttggct gccggcgctg
     8461 cattcttcat gggaacgact gctcatgcgg acgaagctta taccgttcaa tcaggtgata
     8521 ctctatcaac gatttctcaa aaatacgttg gtgataactc cttgatcaat gccattgcag
     8581 aatcaaattc aatttctgat attaacctga tctactcagg acaacaatta acaatcccaa
     8641 cagaaggctc tgcacaagca gctgctgaac ctcaagcagc cgttcaagaa gcaccagtcc
     8701 aagctgaacc tgttcaagct gaacaacctg ttgtacaaga aacggttcaa acggaaacac
     8761 aagcagcgcc tgttgctgaa acacaacctg ctcctgctgt aacagaaact gctgctactc
     8821 cagcaagtac aagctctgca aaagaatgga tcgcacaaaa agaatcaagc ggttcttaca
     8881 cagcaacgaa cggacgttac atcggccgtt accaattaga ttcttcttac ttaaatggtg
     8941 actactctgc tgcaaaccaa gaaagagtag cagaacaata tgttacttca cgttatggtt
     9001 cttgggaagc ggcgaaagca ttctgggaag caaacggttg gtactaagat tcattatttg
     9061 aacgtttaaa cacattcaaa atatagtaag aggtcatgcg atttattctt tcgcatgacc
     9121 tctttttgag tttaagttta gtctttattc cttaactatc gtttgccagt atttcttgta
     9181 tcagaatcta taaatctact atttgaatca atctattagg ttttaaactg tcccaccttc
     9241 acacaaattt tttttgattt atttgaatct ggttccgttg tttaaaattt ttcctatatt
     9301 cttttagata atatgttatt ttctttctca tcgctccagg tgtaccttct ctttataaaa
     9361 aaacaaatta tgcggctaag aagactcgaa cttccacgag gtcaccctca ctagcgcctg
     9421 aagctagcgc gtctgccaat tccgccatag ccgcatcaca tcttttagtt taggattaca
     9481 tgtgtttttt gtcaagaaca tatttttgtt ctttttcatt tctgtacgcc ctcccttatg
     9541 ccatctacac aaataattca tccgagcaac tccatcatct attgagggtt ggtgaaaaaa
     9601 tctgttttat ccatatgatc gatttcaatg ttaaacgaac gactctggga ttagtaacta
     9661 ttttattttt ttcttcattt cttttttcct ctttttctcg attcagctat cttctttcat
     9721 ttggatattg attatttctt ctgttgatta ctatccttct ggaattctag acgctgaagt
     9781 aattcacgtt ttctttcttc tagagatcat aagtaacgaa tgaacgaact tcaaataatt
     9841 tttttattgt aattcatatt tgtattgttc gatgattctt aatacgatat gacacaataa
     9901 ataaaaatag gcatggctat ttacaacaat agtgctatag tagaaaacaa atgaataagg
     9961 ttacttaaag aggtgaatac gatgaaactg atcaaactat gggaagcaga tttaaagaaa
    10021 gcttatcagc tacaaactag ctttggacca aatgagagtg gatttatcaa caatgcttat
    10081 ggctatacat ttgctgaatt tttagattat gtaaaaaaat gcgaaaaaac gtctttagga
    10141 atcgatcttc ctgagagtta cgttcccgca accgtcttta ttttagaaag tgatgaacat
    10201 gagtatgtag gaatttttaa tttgcgccat aaactgaacg aaacattaag aaacggcgct
    10261 ggccatattg gttacggcat ctcccctaat tatcgtaaaa aaggatatgc cacacaagga
    10321 ttagcattag tactacaaga ggcaaaaaaa atcggcattg atgaggcact tttgtctgta
    10381 aatcttaatt gtcaaattaa gttagacaga tcatcaatac ttacgtaact caaaaatact
    10441 tccaaaggtg ttcgataatc cagtgatttt ctaggaatat tatttcgttt agatgcgaca
    10501 gattgaataa aaaattcatc tactgaattg aaatccatag atttcaataa accatctcta
    10561 cgtaacaatc cgttagaatt ctcgtttagg cctctttgag acggcgttcc tggatcagcg
    10621 aaataaatgg caatatcatt gacattactg atctgtttcc aatttgaaaa ttcctttcca
    10681 caatcaaaag tgatggattt gaataggttt ttcggtacag attcaaacca ttgatttaat
    10741 tttttttcaa tatcaatcgc ttgtctacca cacggtttca atgtgatgat aacttttgat
    10801 aatcgttcaa ctaaggtaat tacagcactt ttatgtttca gacctacgat agtgtcacct
    10861 tcaaggtgac caaactcatt tgagaattgg ctataatcct tttcacgttc atgaatagag
    10921 cggcggaaag tttgttttcc acgtctttct tgatgtccat tcggtttacg cttgcctttc
    10981 atcggtaagt cagaagaatc aaatagcccc tttttgaaca tacgataaat ggtacgagca
    11041 gaacaactaa taggaaacgc tgcacgacca acaatcacat cgggtgtcca tccttgaaca
    11101 acctttcttt gaatatattc tgattgttcc tcgggtaaaa caagcggacg tctaccacag
    11161 tttgatttgt ttttcttata ctgttgataa tattctaagg ctgattttcc ttgcttgaag
    11221 aacagatata ctttatggat cgtttgtctt gaacgattca agcaatgggc agttttagca
    11281 acagattgat tcattttgaa ataagactct attattacaa gttcatccgt tgtaagatgg
    11341 gtataggtca tttgtactca ctccttataa ttctttggtc ggaactattt tgagtgtagc
    11401 acaaatgact tttttagttg tctagcttaa ttttacaatc ggcgaaataa aaaaaatctt
    11461 ggcagtctta aagcacaaca aaaaaatggg gctgcgattt atcgtgaaga tgagaaagaa
    11521 tactatacga aaatcaaact gatgtaaaaa agaaggattc caaaaggaaa gggatttgaa
    11581 tgtcctttat caatagaaca catttattta attaacttat aatatagcag acaaaatttt
    11641 ataaacaaag aaacctttta tctcttttct tctagaaagg ataaaaggct tttttgtttt
    11701 tcctatttgc ttctcatagc tagtcagcca agatttctat cgtatcccca acgcaatccg
    11761 tgcataacgg ctcatcttat ctgtcgtcca tgctggatac cagactagtt tgacttctgc
    11821 tttcgttact tctggcactt cttttaatgc gtcatggata gattctgtta aaatatctgc
    11881 taatggacag cccatagttg ttagagtcat cttaatgact gtttctccat tttcaggatt
    11941 gaattctata tcataaatca agcctaaatt gacgatgtcg attcctaatt caggatcaat
    12001 caccatttcc aaggcagcaa gaatacgttc tttgattagt tctatttctt gtccagaccg
    12061 ttcttggttt gcttcgctca tcgtacgaca ctccttaaca cgatttttat ttatcatact
    12121 ctttttttag ctgcttgtaa atgagaattt agaagtaaga ttctcgttta aatttataaa
    12181 aatgttctta ttagatgtaa tagattaaat ttattctaaa ataaacctga ttcctcattt
    12241 tttttgtgaa cgatttttta tttctggcaa tacgccagtt gttcgataca ttttttgttc
    12301 gttttcattt gcaaaccggc caaatactga atgagttggt aaaatattga taaatgcatc
    12361 gtcgtcgatt tcatgaacga tctgatcaag atcatacatt tcgtagcggg tgatgaccat
    12421 catgatcatg ttcccttgtt tttttgaata gccaccgaca gacggcagta atgtcattcc
    12481 acgtaccatc cgttttgcta gttcttctgt tacctcttct ggcttgacgg taacgatcat
    12541 tgctgttact ttttgatgac tcgtgtggat ggcatcaatt acttgagtca ttgcataaat
    12601 ggaaataatc gtatacaagg cactttccca gttaaagaag aagcctgcga tgactacaat
    12661 gataccattt agaatcagca tgtagtttcc gactgttttt ccagttgttt gtgaaagtac
    12721 aagagagatg atatccatcc caccagttgt aaagcccatt tttaaagata atcctacgcc
    12781 aagacctaat aaaacaccgc ctactagggc attcatcaaa atattatcag tgatctgtcc
    12841 gactggaagc agcatcgtca tcaccgatac acatacaaca ttcacaaaac taaggatcgt
    12901 tgctcgtttt cctactttga gaaaccctaa tacaaacaca gggatattca aaagaaaaat
    12961 aaatgttcct gtgtctatct tgatatgaaa ccattcatat aaaagcgagg aaatgatttg
    13021 agcgatccca ttcatccctg cagaaaagac attggctgga atcaaaaaat aatttaaagc
    13081 gaccgcagcg gtcaatccgg ttatcaaaat aaccactatt ttctttaatc tttcattttt
    13141 atgatacgca gtcataattt tactcacaag cacctctccc ctactttggt attccaaatg
    13201 taagaataac agtttatcta ttaaaataaa atacttcgaa ctcaaatgag aagaatttta
    13261 gcaaacaggt aagaatctgc cctaatccta tgataagata gatgtatggt aaatatttat
    13321 atgtatatca ggagggttcc tatggcaaaa gatgctagct tcgacattgt atcagaagtc
    13381 aatacagaag aagtaaaaaa tgcgattcag caaacaacaa aagaattgtc caatcgcttt
    13441 gacttcaagg attctacagt agaaatcaaa ttagagaaca gcaatctagt tgtattgagc
    13501 gatgatgatt tcaaaatcga acagatcaaa gatgtattat ttggtaagct gatcaaaaga
    13561 aatgtgccaa tcaaaaatat ccatttttcc gaatcagaac acgctctagg tggcaaagct
    13621 cgacaaactg ccgatttggt caacggaatc gatcgtgaaa acgcgaagaa aatcactaca
    13681 gctatcaaaa atgaaaaact gaaagtaaaa gcacaaatcc aagaagatca gattagagtg
    13741 acaggtaaga accgtgatga tctacaagct gtgattgctt tattacgtaa acttgactta
    13801 ccaatcgagt tgcaattcac taactatcgt taatcaaaaa acgaggctga cgtctgtcat
    13861 tcctcgtttt tttgatttac tgcttctttt gataaccaaa aacgctgtat tccttcttcc
    13921 aattccccaa cacttcgtac ttctcttgct gtttgccaat gttgtgggaa taaacgtcga
    13981 taagaaaaac tagaaaatcg ttgatctgcc aatacaacga ttccttgatc cgccatgcca
    14041 cgaatcactc gaccaccagc ttgcaagact ttgttcattc caggaagctg ataagcgtaa
    14101 gcaaatccaa ggtgttcctt ctcatcataa tatgatttga tcagttcctg ctcatgattc
    14161 atctgcggca aacctacacc tacgatcata ctgccgatca atcggtcccc tctcaaatcg
    14221 attccttctg aaaaaatccc gccaagtacg caaaatccaa tcaatgtttc agcgggattt
    14281 gtttgaaatt ttgttaaaaa tcgttcgcgt tcttcctcat tcatgtccgt ttcttggatt
    14341 agcacattgc tgtcgggata ttgctgtctg aatgcttcca ccgcaagatc taaatattga
    14401 taagaaggaa agaaaacgaa ataattcccg acctttccat cagcaaaagc atgaatcgtc
    14461 tctactaatt ttgccagact gtgttccctt tttcgataag tcgtctctag gtaatttgcg
    14521 atgaaaactt gctggtttcc ttctgggaaa ggactcggca gtttgtaagc cagacttttt
    14581 tgtcccccca gtgtttcctg ataataagag agtggtgaaa aactagcaga aaaaagaata
    14641 ctgctttttc ctttatccaa cgactgctca agaaacaagc ttggatcaat acaaaactct
    14701 tttactatca gatcgcgata cgttttttcg actgttgttt cgtagtgatc atcataaaat
    14761 tcactgacct tcaaaaaatg aagcaaatca aaataataag gaagcaattg ttcttgtgat
    14821 gggtgctcag gaaattctgc cagccattct ttaatttttt cgcttaattg ataacctgcc
    14881 tttactaaag attcagccgg tgctttttga tgatgataat cccaatgatc ttcttttgct
    14941 atttctcgga tcgaatcaaa ttcttttaat agtttgttga aacggcgatg aagttttttg
    15001 aattcctttg gtatagcttc cttacttcgt ttcgtttttt cataagatag ttctgccgaa
    15061 tacatctctc gggaacgatt caccaaatta tgtgcttcgt caatcaaaaa cagatagtcc
    15121 tcgttttttt catcttcaaa aaaacgtctt aaataaacag ttggatcaaa taaataattg
    15181 taatccccaa tgattacgtc acaccagata ctgacatcta atgatagttc gaaaggacaa
    15241 agtgtatgct ttcttgcata agtttcgatg acttcacgag tgatctgatt ctcatgattc
    15301 aaaagatccc ataaaccttc attaatccga ttgtaataac cattggcata tgggcactga
    15361 tctggattac aggtcgtctc atctaaaaag cagatcttgt ctttcgccgt caaagtgaca
    15421 ctttttactt cagctcctgt atcttttaat gctgtcatag catcttcagc tacttgtcta
    15481 gttattgttt tagccgttag ataaaagatc ttttctccct cttcttcccc tacagctttc
    15541 aaagcgggga ataacgtaga gattgttttt cctgttccgg taggtgcttc tacaaacaat
    15601 ttctgtttcg tacggatcgt tttataagca gctaccgcta gttcacgctg acctttccta
    15661 tactcatcat gggggaattt caaagccatc aaagaggcat tgcgtacagt gcgccagttt
    15721 tcttgaaaaa caagccattc tttataatct tcagtcagct ttttaaaaaa agtttctaac
    15781 tgctctcttg tctgatgttc aacctttctc gtgatcactt cttctgccgt ctggaagtaa
    15841 gtcaattgca gatttatttc ttgtaaatca tgttcttgac tatagatata ggcatacacc
    15901 cttgcttgat gaaagaaaag ttccacttgt tctggttcta aatcttcaaa tcgtggttcg
    15961 gaggttttga tttcatctat ataataaata ccgtctcttt tgaaaatacc gtctgcacgg
    16021 ccttcaacga tcaggtaata ttcatctaat tgaactgttg tttttaaaaa gacttctttt
    16081 tcatagtttt ctcccgcatc tttttggagc ttgcggtgga ttctcgctcc ttctaatgca
    16141 gtatggttac tttttttacg attgtcgata cttccacgtc gcaaaataaa ttctactaag
    16201 tgccgcacag atatttttga ctgtttgatc atttccacca cctctttctc tctaagatta
    16261 cctgaaaaaa cctagtttag caaaaagagc tctctttcca aacataaaaa aacaccctgc
    16321 tgattaggca gggatatagg atatagaatt tggatttttg gatgaatcta atgtaacaag
    16381 gacatattaa aatgctatga aaacttactt tccttctctt tagaatatcc aaatactttt
    16441 catatagtct gataattcag ataagtaaag agaaataagt acctgttttt gtttcctagc
    16501 aatgaatgcg ttatactaat ggatgaaaga agttttggct atcaaggagg aatgcacatg
    16561 catatcgaaa gattaaaaac aggaatgatt gaagaaaact gttatttggt ctacaacgaa
    16621 gaagcacttt tgatcattga ccctggagaa gatgcggaac gaatcaaaca agaaatcaaa
    16681 aaaacaaacc aacagccggt agcgattttg cttacccata ctcactacga tcatatcggt
    16741 gcagtggaac ctttacgcgc gtattatcaa atcccagttt atgtcagccc actagagcaa
    16801 aaatggctag gtgatccgat tttgaatctt tctggactcg gtagacatga tgatattgct
    16861 gatgttattg tctcgcctgc agaatatgaa tttgaaatga aaacttatac tttaggaaac
    16921 atgtcttttc gcgtcgtccc taccccaggg cattctatag gaagcgtcag ctttattttt
    16981 gatgattttg tcgtttctgg cgacgccctg tttagaggaa gtatcggtag aaccgatctg
    17041 tatacaggga atttagaaca attacttcat agtattcgga cccagctgtt tgtattacct
    17101 gatgaatttg cagtctatcc aggacatggc gatgcaacga cgattgaaca ggaaaaaagg
    17161 acaaatcctt ttttcaatcg ttaaaacgac ttaggaggag aataaaatga cagaaactac
    17221 actttatatc gtacgacacg gaaaaacgat gttcaataca attgaacgag tacaaggctg
    17281 gtgtgataca cccctcacaa agcaaggaca agaaggcatt cattatttag gtcgcgggtt
    17341 aaaaaatgtc gacttttcat ttgcttattc tagtgacagt ggtcgtgcaa tcgaaactgc
    17401 ccgtattatt ctaggagaac attctaaggg aaaagaaatt ccttatttta ttgaaaaaag
    17461 gattagagaa tggtgtttcg ggtctcttga aggtggatat gacatggaaa tgtggggtgt
    17521 gatccctcgt gtattgaatt ttaaaacata tgatgaaatg tttaccacag aagtttcttt
    17581 tgaacaaatt gctaatgctg tatacaactt agataccgct gggtgggcgg aaacttatga
    17641 aacattgcga gaccgtgtat ggacaggatt tgaagatatc gcccatcact gcgaaaaaaa
    17701 tggtggtgga aatgttttag tcgtatctca tggtttgacg atcgcctttt tgcttaatct
    17761 gatcgatcct aaacagcctg ttcgtgctgg gcttttaaat ggcagcgtaa caaaggtcac
    17821 ttatgcaaac ggtcgatttt ctatccacgg catcaatgat acgtcttata tcgataacgg
    17881 gaaaacacat agtcgcgact cgtttctata atggggatat tttaattttt accagagaat
    17941 cataaaaggc aaagtctgaa cgagggcttt gtcttctttt ttctcttcgt gtacttatct
    18001 gctttatttc tcaagttttt cttaat
//
LOCUS       DAFKHN010000052        17541 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFKHN010000052 DAFKHN010000000
VERSION     DAFKHN010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.052"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(41..850)
                     /locus_tag="LY912_001861"
     CDS             complement(41..850)
                     /locus_tag="LY912_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBM6955536.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1143..2579
                     /locus_tag="LY912_001862"
     CDS             1143..2579
                     /locus_tag="LY912_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBM6955537.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2749..3945
                     /locus_tag="LY912_001863"
     CDS             2749..3945
                     /locus_tag="LY912_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBM6955538.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4007..4192)
                     /locus_tag="LY912_001864"
     CDS             complement(4007..4192)
                     /locus_tag="LY912_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBM6955539.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4423..7737
                     /gene="dnaE"
                     /locus_tag="LY912_001865"
     CDS             4423..7737
                     /gene="dnaE"
                     /locus_tag="LY912_001865"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBM6955540.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLGPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            7904..8866
                     /gene="pfkA"
                     /locus_tag="LY912_001866"
     CDS             7904..8866
                     /gene="pfkA"
                     /locus_tag="LY912_001866"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBM6955541.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8940..10724
                     /gene="pyk"
                     /locus_tag="LY912_001867"
     CDS             8940..10724
                     /gene="pyk"
                     /locus_tag="LY912_001867"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBM6955542.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10759..11661)
                     /locus_tag="LY912_001868"
     CDS             complement(10759..11661)
                     /locus_tag="LY912_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBM6955543.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11847..12416
                     /locus_tag="LY912_001869"
     CDS             11847..12416
                     /locus_tag="LY912_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBM6955544.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12474..12653
                     /gene="rpmF"
                     /locus_tag="LY912_001870"
     CDS             12474..12653
                     /gene="rpmF"
                     /locus_tag="LY912_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBM6955545.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12823..14244
                     /gene="gndA"
                     /locus_tag="LY912_001871"
     CDS             12823..14244
                     /gene="gndA"
                     /locus_tag="LY912_001871"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBM6955546.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14437..15123
                     /locus_tag="LY912_001872"
     CDS             14437..15123
                     /locus_tag="LY912_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6955547.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15120..16625
                     /locus_tag="LY912_001873"
     CDS             15120..16625
                     /locus_tag="LY912_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBM6955548.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            17312..>17541
                     /locus_tag="LY912_001874"
     rRNA            17312..>17541
                     /locus_tag="LY912_001874"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         5675 a         3060 c         3681 g         5125 t
ORIGIN      
        1 aaattgtcac aacctctttt ttgtggaatc taattctcta ttatagttta agtagttttt
       61 ccagataaac agctaaaccg tcttcctgat tgctcaaagg agtgacatca tttgcaatgc
      121 ctttgagttg gtcagtaccg ttagccatag ctactcccca acctgcataa tccaacaatt
      181 ccaaatcatt atgctcgtca ccaaaggcaa tgacgtcttt ttgatcgata gacaggtagt
      241 tagcaatctc ttgcacgcct tttgcttttt ggattccttt tgaaacaatc tctaagatgg
      301 cagtaggtcc accccatgtc cgaacatcga cataactgcc aaattgacgt gttaattcag
      361 cagatacagc tcctgcaaaa cgtttgtctg ttcggacaag caaagatgta ggatttgtcg
      421 tcaaattttt aggagaaagc aaattcttct ctcctggacg agaagaagca aaaatttttt
      481 catcaaagaa atcaaaactg tcaataaaaa aagtatcacg attttcagca gcgataaaat
      541 ctaaatttag ctgctttttt tgcgataaga tttcaaaagc gatttcacga ttgatcaacg
      601 tttctctttc accatcccag tgctgattag ggatgtgtac taatgcgccg ttaaaattaa
      661 ccatcggtgt tgttaattct aattgttggt aaaactgatg gctcattcgg aatgggcgtc
      721 ctgtagcaat actgacatga tgaccggcat tgattgcttt ttttagagtc tcttttgttt
      781 tagatgtaat catcgaatct tgattgaggg tagttccgtc cagatcgatg gcaattaatt
      841 ttttattcaa taagggtcct tccttcctca actagcattt gttttagtct agcatatttt
      901 aggtaattaa caagagcaat cagctattcc taacaaaaac tacagttatg gctatataaa
      961 tagctaaaca taagctaaac acgaacgtta agtattattt tcgctttttt tgttaaaaaa
     1021 acgttgaaaa gcgaatgaaa cgtctatata atttgaaatt gttcgatgga tttgccctat
     1081 tttacttatt ttttattatt atagttttcc atcagaaaaa aattcaggga gtggaacttt
     1141 ttatggaaaa gtttttcggt ttaaagaaaa acaatacaaa tgtatcaact gaaataatgg
     1201 cgggagtaac gacattcttt gccatgagtt atatcttatt cgtaaatccg acgattttgt
     1261 cagcatcagg tatgcccttc caagcagtat ttctagcgac aatcattgca tcgattattg
     1321 gtacgctggt aatgggattg ttcgcaaatg taccatatgc tcaggcacct ggtatgggat
     1381 tgaacgcatt tttcactttt acggtcgttt ttgggcttgg ttattcttgg caacaagcct
     1441 tggcaatggt gtttatttgc ggattaatca atatttttat tactgtcaca aatattcgaa
     1501 aaatgattat tcgggcgatt cccgaaagtc ttcaacatgc gattggtggc gggatcggta
     1561 ttttcgttgc gtatgtcgga atcaaaaatg caggattctt atctttttca gcagaccagt
     1621 cagctatttc gagctctgtc gttgaaggcg gaaaagcgac aaatgttacg ataaatggtg
     1681 gaatcgtccc tgcgttagcc aactttgaca acgctcctat cttattggct gtgattggtt
     1741 tggtactgac agccatttta gttgtaaaaa atgtccgtgg ggctattctt atcggtatcg
     1801 tagcgaccac agtccttggt atttttatgg gtgttgttga tttaagttcc attgattggc
     1861 aaacgaattc gttaggtaat tcatttaaag aattaggaac aactttcggt gcagcatttg
     1921 gttctgaagg catgcaatct ttattcagtg attcttccaa gattcctcaa gtattgatga
     1981 cgatcatcgc attcagttta tctgatactt tcgatacgat cggaacattt atcggtacag
     2041 gacgccgcac aggtattttc tcaaaagaag acgagatcgc gttggaagat ggtcgtgggt
     2101 tcaaaacaaa aatggataaa gcactatttg ccgatgcgat cgctacttct gtgggggcta
     2161 tctttggtac atcgaataca acaacttatg tcgaatctgc agctgggatc ggggccggtg
     2221 gacgtactgg tttgacttca gtagtagtgg cagtgctatt cgcattaagt agtttattct
     2281 ctccactgat cgccattgta ccaaatcaag caactgcgcc agcattgatt ttagttggag
     2341 taatgatgat ggcttctttt gcagacatca aatggctaga tatggaagaa gctttaccgg
     2401 ccttctttgc atcgatcttt atgggattgt gctatagcat ttcctatggg attgcagcag
     2461 gatttatttt ctatacaatt gtgaaagtaa tcaaaggaaa atacaatcaa gtttctgttg
     2521 ctttgtggat cgttgatatt ttattcatta tcaacttcat cattctagca acaatttaac
     2581 taaagagaag ggattggaac agtatttgtt ctgatctctt tttgttttac ataaaaagaa
     2641 cgttacatat aaaatgacct ttgcgggatt tttctctttt tactggcgag atcgttgctt
     2701 gtttattcga aaataggtat gataaaagag acgaaagagg gatgatagat ggagattaat
     2761 tggagaaaaa atttagtgat tgcgtggatt ggctgttttt tcactggtgc aagtattagt
     2821 ttagttatgc cattcatacc agtttatgtt gagcaactag gaacaccaaa agatcaaatc
     2881 gaattgtttt cgggactagc aatctctgtg actgcttttg catctgccgt ggttgcacca
     2941 atctggggaa atctagctga tcgaaaaggc cgaaaactca tgatgatccg tgcagcagca
     3001 gggatgacat taacaatggg atctttggct tttgtaccaa acgcgtattg gcttttgatc
     3061 atgcggtttt ggaatgggat tttgtctgga tatattccaa atgccacagc gatgattgct
     3121 tcacaggcac ctagagaaaa gagcggatgg gcgttaggaa cattgtctac cggagcgatt
     3181 gctggaaatc tgatcggacc ttcaatgggc ggtgcactgg ctcagtggtt tggtatggaa
     3241 aatgtattct tgatcacagg ggctttgttg atgatcacaa cggtattgac cattttctta
     3301 gtcaaagaag atttccatcc aatcgagaaa aaagatctga taagcaccaa agaaattttt
     3361 tcaaaaatgg atcatctctc tattttgatc ggtctcttca ttacgacctt gattttacag
     3421 ataggaatca ctacgatcag ccctattttg accttatata ttcgtgaatt gagcggaagt
     3481 acagaaaata tcctttttgt cagcggcttg attgtttcga tagctggtgt ttccgctgtc
     3541 ttttcttcac cgaaactagg aaaactaggg gataagattg ggaatcaaaa agttctaatt
     3601 ggaggactca ttttatcatt ttgctgttat ttacctatgg cattcgtcac tacaccgctc
     3661 caattaggta tacttcgctt tattttaggc ttttcaactg gcgctttgat gccttctgtc
     3721 aatacactga tcagtaagat tacgcctcaa gaaggagtca gccgaatcta tagctacaat
     3781 cagatgttta gcaactttgg acaagtttta ggtcccatgc taggatcgac agtcgcgcat
     3841 gcttataatt acagtgctgt ttttattgtg acaagtttgt ttgttctgtc aaatattctt
     3901 ctttctttat tcaactttcg taaagttctt cgcagcagat tataatggtg gtgaggagta
     3961 gaaaataaaa aagagcttga gaaatctcaa gctcttggct gtttttttac gaatgggcag
     4021 aggtttcttt tcttggcgca actgcaccaa tcaaaaggat aatgacaccc gcaatgaatg
     4081 aaatgattgt tgtcaaagta aaatcatatg ttccgcttgt taatgcagca ccaatataac
     4141 cgactacttg acctagaacg acagcccaga ataatgtaac gatatatcgc ataaagaaca
     4201 cctcttttct atcttaattt taccagattt tctttgaatg taaagaaacg agaccaaatc
     4261 tcaataaaat ttgagttctt gcgaaagaac tcattcctac agattacaag caagcaaatg
     4321 aagtggaata atcaacttca gcgcctgcta tcttaatgaa agtaaaagga tcaaaccttt
     4381 taacgctagt gaattttaac gaaaaaaaag gcggaatgca agatgttttt cccacaactt
     4441 tatacaatta cttcttattc tcttttacaa agtacgatac gtattcgaga atatgtacaa
     4501 gaagcaaaaa aacaaggcta cacttcatta gccataacgg ataaagatgt cttatacggt
     4561 gcacctgaat tctatcgtat ttgtgtagaa gaaggagtac agccaatcat tggattacat
     4621 cttagttata cttatgaaga aaaaaattat ggcttgcttg cgtacgcaaa agatgaaata
     4681 ggttatcagc agctgatgaa actttccagc cgaaaaatga tccaagaaaa attggaactt
     4741 gcagaaatga cagaaaccga ccatctagcg tttgttgttc cggcaaatca ttctgtttct
     4801 gaggctttca ataaagagga taactttttc ggtcattggc agtttttact tgaaaatgtt
     4861 tttactagaa atttttatat cggcttgaca gaaaacacgc ctgatcaatt gcctgaatgg
     4921 tatcagtatg tgataaaaga aaattattcg ctttgtgcat tacatcccat cgctagttta
     4981 caacaagaag aactttttgc acttgaagtg atgaaacata tcaaagaggg aagccaaata
     5041 cctttagaaa atttatctgc atctttacca ctaacagcaa atgtctatct tctttcagaa
     5101 caagaaatga tcaaacgatt cgaaaaagcg ggtctttccc aagctgtaat aggcgcccag
     5161 cgtttagctg aatcgatttc atttgaattc cagttccatc agaaattact tccgcattat
     5221 ccagttccta atggaaaaca agctggagaa tatttaagag agttatgcta ttcgcaagtg
     5281 gaacgccgaa tcactgacta tacaaaggaa taccaagaac gtttggacta cgagttatct
     5341 gtcatccatc aaatgggatt cgatgattat ttcttgatcg tatgggatgt aatggctttt
     5401 gctcatagaa acaaaatcgt taccggtgca ggtcgtggtt ctgctgcggg ttcattagta
     5461 gcctatgtgt tagaaatcac agatgtggat ccattagaat atgatttgct gttcgaacgc
     5521 tttttaaacc ccgaacgctt tacgatgcca gatatcgatt tggatattcc tgacaatcga
     5581 cgtgaagaag tattgaatta tgttcgagaa aagtatggac aatatcatat ggcacaaatc
     5641 gcaacatttg gcacaatggc agcaaaaatg gttcttagag atgcagctag agtgtttggt
     5701 ttatcgcaaa gtgaagcaaa ccgctggtca aaagcaatac ccaatcaatt gaaaatcaca
     5761 ttgacccaag cttataaaac ttcgcatcaa ttagtagaat tagttcaggc aagcgaaaaa
     5821 aaccaacttt tattcaaaac tgcagtgatt ttagaaggat tgccaagaca tgtttcgact
     5881 cacgcagcag gtgtagttat cagcgataag aatctacttg aactagttcc gctccaacgc
     5941 ggttctgatg aagcttttct gacccagtat acgatgaatg aggtagaagc aatcggtctt
     6001 ttgaaaatgg actttttagg actacgcaac ttatcgatta ttgattttac tttgaaagct
     6061 gttaagcgag tagaagggta tgagatccga ttaaaagaga tcccgctaaa tgatgcaaaa
     6121 acgctgctct tgtttcaacg aggcgaaacc tcaggagtat ttcaatttga atctgctggt
     6181 atccggaacg ttttacgaag attaggtcca gaaaacatcg aagatattgc cgcagtcaat
     6241 gcattgtatc gaccaggccc tatgcaaaat atagatacct tcattgccag gaagaaagga
     6301 aaagaagcca ttcgctaccc agatgattca ctgatcccga ttttgaaaaa cacatatgga
     6361 gtgatcgtct atcaggaaca aatcatgcag atcgcctcga ctatggctgg atttacatta
     6421 gggcagtcag atattctgcg acgggcagtg agtaaaaaga aaaaagacgt attagatgaa
     6481 gaaaagtcgc attttgtatc aggagcatta caacagggat attcggaaaa aacagcagcg
     6541 accgtatatg aatatatcga aaaatttgca aactatggat tcaatcggtc acatgcattt
     6601 gcttattcat tcgtgggatt ccaaatggcg tatctaaaag cccatcatcc aggtgctttc
     6661 tttaccagcc tgatgaattc tgttcggcat aacacatcaa aattgaaaga atatattgca
     6721 gaagcacgta aaaataaact caaactttcc tcgccgtcca ttaatcaaag taattccagt
     6781 tttgagttgg tcaataagga agaaatcaga ttcggactga cagcgataaa aggtattcgg
     6841 cgtgattttg tagaagatat attaaacgaa agaaaacaaa atggcccgtt ccagtcagtg
     6901 gatcaattcc tcatacggat cgataagcgt tggctgaaat tagagttact gcaatcactg
     6961 acagcagtag gcgtttttga tgaattatct cctaacagga aacaattgat gcttgatctc
     7021 gaaggaaaaa tccaaaatat cgtttacagt ggtggaagtc ttgacttgct gggaatcatg
     7081 gcattaaaag aagaagaagt cgctgactat acactagaag aacgcttgaa gctggaagag
     7141 gagtacttag gtatttattt gtcaggtcat cctgcagaag ggtttgatcg tcttcgttta
     7201 gctaaacaag ttcagctgat tacagatatc gtccctaatc aaccagtcaa tttattagtg
     7261 atgatcaagg aagttagaga aattcggaca aaaaaaggag aactgatggc ctttgttgaa
     7321 ggaaccgaca gtagtggaga aatttctgtc acagtttttc caactcttta tcgtaaatat
     7381 cgtaatttgt ttgccgttga tcgagtgatc tttgttcaag ggcggagcga aatcagcaaa
     7441 tataatcagg aactgcaact aattggagaa agctttgctg atcctaacca gttagaagcc
     7501 cagtatcctt cacaaacttg ctatttgcgt attacagaag aacgggaaga tcccgagata
     7561 atgaaacaat tacaagtgat ttttcagaaa cacccaggat atataccagt agttatgtat
     7621 cacgaaaaaa cgcaacgaaa agtagttctg tcagatgctt attgggtgga tgacagcaag
     7681 agtataaagg ggcaacttat ttatctgctt ggcgaagata atgtggtttt caaataactt
     7741 acggtaaaaa atactacttg ctttcatttt tttcattttt ttatccgtaa atcaagacaa
     7801 gtgagaaaaa taatgttaga atgttagtcg tggttaacgc aaaaatggtt gtaaacctaa
     7861 gtcatactta ggataaagta ttttaatgag gtgaatgttt attatgaaac gcatcggaat
     7921 tttgaccagt ggcggagacg cacctggaat gaatgcagct gttcgtgccg ttgttcgtaa
     7981 aggtatttac gaaggactgg aagtatacgg gatcaattat ggttttgccg gtttagttgc
     8041 tggagatatt cgtcgtcttg atgtggcaga tgtaggtgac aagatccaac gtggtggtac
     8101 attcttgtat tctgcacgtt atccagaatt tgcaactgaa gaaggtcaat taaaaggaat
     8161 cgaacaattg aaaaaattcg gaatcgaagg tctagtggtt atcggaggag acggctctta
     8221 tcatggcgca atggctttga caaaacgcgg tttcccagca gtaggtattc ctggaacaat
     8281 cgataatgat attcctggga ctgatttcac aatcggtttt gatacagcaa tcaatacagt
     8341 actagaatca attgaccgta ttcgtgacac agcgacttct catgttcgta cattcgttat
     8401 cgaagtaatg ggacgcaatg caggagacat cgctttatgg tcaggtgtgg ctggcggagc
     8461 ggatgaaatc atcatcccag aacatgattt tgatatggct tcagttgcta aaaaaatcca
     8521 agaaggccgc gatcgcggga agaaacattg cttgatcatc ttggctgaag gtgtaatggg
     8581 cggaaatgaa ttcgctgaga aactttcaga atttggcgac tatcatacac gtgtatctat
     8641 cttgggacac gttgtccgtg gtggagcacc aagcgcacgc gaccgcgtgt tggcaagtaa
     8701 attcggtgct tacgctgtcg aattgcttca agaaggaaaa ggtggattat gtgtcggtat
     8761 ccatgacaac gaaatcgttg cgtctgacat cattgataca cttgaaaaca acaaacataa
     8821 accagactta tcactatatg atctaaataa ttcactttca ttttaagagt gaaagaaacc
     8881 aagctattta agctgtgtac agctttaaat aaacaaaatt gaatgggaga gttttttaaa
     8941 tgaaaaaaac caaaatcgtt agtacattag gaccagcaag taactcagta gaaattattt
     9001 ctcaattgat tgaatctggg gcaaatgtct tccgctttaa cttttctcat ggtgaccatg
     9061 aagaacaatt atcacgtatg actatggtcc gtgaagcagt taaaaagaca ggaaaagatg
     9121 tcggtattct tttagataca aaaggagctg aaatccgtac aactgttcaa ggcacaacag
     9181 aagctgattt tggtcgtgca ggatacatca aatttgaagt aggagatcaa acacgcatct
     9241 ctatggatcc tgaacatgta ggttcaaaag aaaaaatcgc ggttacttac ccaggattat
     9301 ttgacgatgt tcacgttggc ggacacattt tatttgatga tggtttgatc gatatgcaaa
     9361 tcattgaaaa agacgaagca aaccgtgaat tagtcgtaga agttaaaaat gcaggtatgc
     9421 taggatcacg taaaggggta aatgcaccag gcgtttctat tagtttgcca ggtattactc
     9481 caaaagatgc tgacgatatt cgttttggtt tagacaacga tatcgacttt atcgctgcaa
     9541 gttttgtacg taaagcacaa gacgttctag atatccgcga aatcttagaa gaaaaagaca
     9601 tgactcatgt tcaaatcttc cctaaaatcg aatctcaaga aggtatcgac aacattgacg
     9661 aaatcatcaa agtttctgac ggtgttatga ttgcccgcgg agatatgggt gttgaaatcc
     9721 cagctgaact agtaccaatg gttcaaaaac gcatcatcaa aaaatgtaat gctgctggta
     9781 tcccagttat cactgctaca caaatgttag aatcaatgca agaaaaccca cgtccaacac
     9841 gtgcggaagc ttctgacgtt gctaacgctg tatttgatgg cacagatgca acaatgctat
     9901 ctggtgaatc tgcaaacggg gactacccag ttgaagctgt ttcaacaatg gcacgtatcg
     9961 accaagaagc tgaaaatgca ttatcagaat taggtacatt ccaattgaac gaattcgata
    10021 aaacagatgt aactgaaaca atcggtttat ctgtagctcg tgctgcaaaa aatctaggcg
    10081 tgaaaacaat cgttgctgca actgaatcag gatacactgc aaaaatgatt tcaaaatatc
    10141 gtccagatgc agatatcttg gctgttactt ttgacgaacg cacaaaacgt ggtttgatgt
    10201 taaactgggg cgtttaccca acagttgctg aaaaaccatc aacaactgat gaaatgtttg
    10261 aactagcagc taaaaaagct gttgaattag gtttcgcatc agaaggcgat ttaatcttga
    10321 tcactgctgg tgtaccagtt ggtgaacgcg gaacaactaa cgtgatgaaa attcaaatga
    10381 ttggttctaa attattagaa gctcaaggcg ttggacaaaa atctgtcgtt gcaaatgcag
    10441 ttattgcttc atctgctgaa gaagctgtaa aaaaagcaaa agacggaatg gttctagttg
    10501 taccatcaac tgacaaagaa tatatgcctg caatcgaaaa agcagctgct gttatcgttg
    10561 aagaaggcgg attgacttct cacgctgcag ttgtaggaat tgcacaagat attcctgtaa
    10621 tcgttggtgc taaaggcgca acaacaacaa ttacagaagg tgaattgatt accgttgatt
    10681 cacgtcgcgg catcgtttac cgtggcgaaa caacagctat ctaatttagc ttaataaaaa
    10741 ataaaaacag ctcttctttt acgaagagct gtttttttgt gctgtaacga attcatggat
    10801 aacttggact acttgttctt gaagaggcgt gacgatctgc tgtgttcgtt ttgccaatga
    10861 aatcaagaag cgaggctgaa cttcatctga aagagggagg caaactaaat gatcttcagg
    10921 atggacagca atctctgcca aaaaaccgat acccacattt tctcggacca tactctttaa
    10981 aatcgtcaag tcattgcttt gataaacaac ttttggatga gtatgtgttt gtttagaaag
    11041 cttagtgaat gctgcggggt ggacataatg ttcgttcaat agtacaaact gttcatctgc
    11101 tatatctttg aaagagacag tatcctgctt ggaaagagga tgtgtaggtg gcacgacgat
    11161 catgaaacgt ttgtccaaaa gtaactctgt ttctaaatat tgatccacga ttggctgtgt
    11221 tgagcctaat acagctaaat cgatcctccc ttgtcggatc atcccgtata agtcccgaga
    11281 gcctccatcg gtaatctcaa tttgattcat caattcatgc ttgataaagt aacttgacag
    11341 tttaggaaag tattcattgc cgataatagg aggcatgcca aaacgaagct ttttcttttg
    11401 caactgagtg atttcagctc ttgcagtaga aatctcttgg agaatggttt gtgcatggag
    11461 aaacagctgc tttccagaag gcgtgacgat taattcgtga tgcgatcgat ctcttgtaat
    11521 aagtacggtg tcaaactctt tttcaagacg ttgtaatgca tatgtaatag taggttggct
    11581 cacacggaaa taattagcca ctttcgtaaa atttttttgt ttgacgattt ggacatagta
    11641 ttcgatatct ttcgtgttca tgaagatcat ccgctccttt aatggaataa tgattattgt
    11701 aaatgattct gaggatgata gcaaacagag gctttctaat aaagattttt ctgttttttt
    11761 atgaactgca aggtgtcaag aaaatttcat tgacaacatg ctttttgccc tgtataattg
    11821 cttttgttgc ttaggagtga tgaaaaatga aatggtcttt attggaattg agaaaatacc
    11881 aggagacacc gttaactttt catgagacgc tcgacttgaa agccgctctc atgaagcgag
    11941 acaatttaat acttgatgtt gcgccagtgg aagtcgaagg tttggtctca gttgataaga
    12001 aaggctatat cgttcattac actgtgcaga cgactttgac agttccttca acacgttcac
    12061 tagaacctgt tgaactgccc atggattttt ctgtagacga agtattcatg acagaagaac
    12121 aattccaaag tagagatgaa caaatgtctg cggatgagat tttgctaatt gaaggtccat
    12181 tattgaattt agcagagtcg attgaagaca acatcttatt ggcgattcca atgcgggtat
    12241 tgacaaaaga agaggaagca gcaacagaac ttccaaaagg caatgattgg gaagttgttt
    12301 ccgaagaaga ataccagcgc agaaaaatgg aagaagccga gaataaaatt gatcctcgtc
    12361 ttgcaaaact atctgaactt tttgattcta aatcaaaaga cgacgataac aagtaagatt
    12421 ggaatatatt gtgtctaatt tagatacaag actttacaag gaggtgtagc aaaatggcag
    12481 taccagctag aagaacatca aaagctaaaa aagcaaaacg tcgtacacac tacaaattga
    12541 caatcaaagg gttaaacgaa tgtccaaact gtggtgaaat gaaaaaaagc catcacgtat
    12601 gtgcaaattg tggttactat gatggtaagg acgtaatgtc aaaagaagct taatacattt
    12661 taattagaaa atgtaaaacc tcaaggctaa ccatggagcc ttgaggttta tttttttgta
    12721 gtcggtaaat aaaaaatatg ttgttcttta gtttgcaatg tagccgtgtt aagctataat
    12781 gtaagagatt agggagaaat cccgtatgta ggaggagttc atatgtcaaa acaacaaatc
    12841 ggcgttgtcg gtatggccgt tatgggtaaa aatctagcct tgaacataga aagccgcggc
    12901 tattcagtgg ctttattcaa tcgtacaggg gctaaaacaa ccgctgtagt agaagaacac
    12961 ccagataaaa atttcaaagc aacatataca atcgaagaat ttgtagaatc tatcgagaaa
    13021 ccacgtcgga tcttgctaat ggtcaaagca ggaccggcaa cagatgcaac gatccaagag
    13081 ttgcttcctc accttgataa aggcgatatt ttgattgacg gaggaaatac attctttaaa
    13141 gatacgatgc gtcgtaatga agagttagcc aactctggca tcaactttat cggtacaggc
    13201 gtttccggtg gtgaagaagg agctttaaaa ggaccttcaa tcatgcctgg tggacaaaaa
    13261 gaagcctatg cgctagttgc accaatctta gagcaaattt ctgcaaaagc agaagacgaa
    13321 gcaccatgtg tcacatatat tggcccaaat ggagccggac attatgtgaa aatggtacac
    13381 aacggtattg agtatggaga tatgcaactg attgctgaat cttatgactt aatgaagaat
    13441 attttaaacc tttcagtaga agaaatggct gatatcttta aagaatggaa tcaaggcgaa
    13501 ttagacagct atttgataga aatcactgct gacattctga cacgtaaaga cgatgaagga
    13561 acaggtaaac cagtagtaga tgtgatcctt gatgcagctg ggaataaagg aacaggtaaa
    13621 tggacaagcc aaagcgcgct tgacttaggt gtgccacttc cattgatcac tgaatctgta
    13681 tttgcccgct atatttctgc ttataaagaa gaacgcgtac aagcaagcaa gattttatct
    13741 cgtacgaacg attttgagtt cacgggagac aaaaaagaat tggtcgaaaa aatccgagaa
    13801 gcgttgtatt tcagtaaaat catgagttat gcccaaggat ttgctcaatt acgtgtcgct
    13861 tcaaaagaat ttgattggga cttgccattt ggtgaaatcg caaaaatctg gcgcgctgga
    13921 tgtatcatcc gagctcgatt cttgcaaaaa attacggatg cctatgacaa aaatcctgag
    13981 atcgaaaatt tattgctaga tgattacttc gttgaaatca cgaaaaaata tcagcaatca
    14041 gtcagagacg tcgttgcctt ggctgtccaa gctggcgtac ctgtaccgac tttctcatca
    14101 gccatcgctt acttcgattc atacagagca gaacgtctgc ctgcaaatat aatccaagcc
    14161 caacgcgatt actttggcgc acatacctat gaacgtgtcg acaaagaagg aatcttccat
    14221 tactcatggt accatgaaga ataatagtct ttcggctgtt aggaaatgag aaaataaaaa
    14281 gaggacgaaa gagctgaagt cgattgttat gagtagactt cagctctttt ttaaaattgc
    14341 tatccatgat aaaatgacta tagattttta agcatattat cggtataatg atagagtttt
    14401 taaaaagcca gtagaataga aaggataaaa taataaatga gcaatattct aatcattgaa
    14461 gatgaaaaga acttggcacg atttgtcgag ctagagttga agcatgaagg gtataacgca
    14521 gaagtccact acaacggccg aactggttta gatgcggcat taaataatga gtgggatgcc
    14581 atattgttgg atctgatgct cccagaattg aacggtttag aagtctgcag acgtgtacgc
    14641 caagtcaaaa atacaccaat cattatgatg actgcaagag attctgtgat cgatcgtgta
    14701 tctggacttg accacggagc agatgactac atcgtcaaac catttgctat cgaagaatta
    14761 ttagcacgtc ttcgtgcatt gttgcgtcga atcgatattg aaggcgataa aaatgtggct
    14821 aaacaaacta ctattactta tcgcgatttg actatcgaaa aagaaaaccg tgtcgtacgt
    14881 cgcggaaatg aagtaattga actaacaaaa agagaatacg agttgctgct tactttaatg
    14941 gaaaacgtga acgtggtatt agcacgtgac gttttactaa ataaagtgtg gggatacgaa
    15001 acagaagttg aaacaaacgt agtggacgta tatattcgtt atcttcgcaa caaaattgac
    15061 gttcccgggg aggaaagcta tatccaaact gtacgcggaa caggttatgt gatgcgctcg
    15121 tgataaagcc gaaaaaatcg gaaaaaagag aactgaaagg gccctccttg acaatcaagt
    15181 gggcctttgc gagttctttc ttcatattcg ttgtgtttac aattttcgct gtcattacct
    15241 ataaatcatc tatcaatctg attgtggcaa aagaaagaaa caatgtagag cgtacgattt
    15301 cagaagtagc ttctcgtttg gctaactcgg atgaagaact gacattagta aatacgtatc
    15361 gtaatctgac gaaagcgaca aatgacggag atgaggtcgt agatcatact tcactggtcg
    15421 aaggaaactt aatgaagatc gattccttta tagctgagct agggcagcca tcaatggatc
    15481 tttatgttta tgatttggac gagaacttga tttttaaaac ccatgaaaac agtcgaaacc
    15541 tgattcagac tacacgtaaa gttccaacga tcgttacact agaaggaaaa actggctttt
    15601 tatctatcca gcctatatat tctaaaggta caagagaaaa gatcggctat gcgcaaagct
    15661 tctatgaatt atcttctttc tatgatattc gaaataagct attattgact cttattgttt
    15721 tagaagttgt ttctttgatc ttaagtagta ttttaggttt ctttttatct tcttatttct
    15781 taaaaccact caaggtactc agagatacaa tggatactat acgtaaagat ccgcaatcag
    15841 atatccacat gcctgaaatc gacacaaatg atgaattggc agatttagct gaaatattca
    15901 atgagatgct tgaccgtatg cgtttgtata ttgaacaaca agagcaattc gtggaagacg
    15961 tatctcatga gttaaggaca cctgttgcaa ttattgaagg gcatcttagt ctgctaaatc
    16021 gttgggggaa agatgatcct gagatattag aagaatcatt aagcgccagc atgcaagaaa
    16081 ttagccgtat gaaaagctta gttcaagaga tgctagactt atcaagagca gaacaagtag
    16141 atgttcatta tgcgaatgaa acaactaaag gaaaagaagt cacctatcaa gtttataata
    16201 atttcaagat attatatcca gactatgtga tcactttaga tgatgatttg acaaaagaag
    16261 tgaccctgca aatttatcgt aatcactttg aacaattaat cattatcata ttggataacg
    16321 cagtaaagta ttcaactaca cgaaaagaag tccatatctc tatttcttcc actctgaatg
    16381 aatttgagat cgcgattcag gactttggcg aaggaatacc caaagaagac cttaataaga
    16441 tcttcaatcg tttttatcga gtggataaag caagagctag aacgaagggt ggaaatggtc
    16501 tggggttgtc tatcgctaaa caactggttg aaaactataa aggacgtatc ttagcagaaa
    16561 gtgtagtagg gcaagggaca atttttagaa tctttattcc tatcgcaaag gcagaagaca
    16621 agtaaagcat gtgctttact tgttttttta tatatccaac aaagaataag gtacaaaata
    16681 caagcaagtt agaaattcag ggatgtcatt ataaaaaaaa ctagcgaaca attaaataga
    16741 ataacatccg ttaattaaac gtaagtagct tttagatgaa cgaaaaaaca atgaaatgct
    16801 gtaatattcg tgtttaaaaa taataaataa aaatagggaa ttttctattg caattttata
    16861 aagagattgc tatattatta tttgttctaa atgattcctt taaggtgtca ctaaaaatta
    16921 taaaaaatag ggttgacgca cttttgatgt catgttataa taacgaagtc gtttggatga
    16981 ggtagctaat aaagcttgat tttatcgaaa aaaacttcga aaaagttgtt gacaaataac
    17041 aataaagatg atatgataat caagtcgctg ctaatgagtg acaaagacgt ttagaaaaaa
    17101 taaacaaaga agttgttgac attctcttct gaatctgata agattaaaga gttgttgaaa
    17161 caaaaagatt agacctttga aaactgaaca aagtaagaca aaccaaatgt gtagggcgtc
    17221 ttgattcaat tcaagacaac aaacattttt aacaagcaag caatatgcta gcaaacaaat
    17281 tgagcttaac aatcgcaaga ttgttcgaac tttttatgag agtttgatcc tggctcagga
    17341 cgaacgctgg cggcgtgcct aatacatgca agtcgaacgc ttctttttcc accggagctt
    17401 gctccaccgg aaaaagagga gtggcgaacg ggtgagtaac acgtgggtaa cctgcccatc
    17461 agaaggggat aacacttgga aacaggtgct aataccgtat aacaatcaaa accgcatggt
    17521 tttgatttga aaggcgcttt c
//
LOCUS       DAFKHN010000053        17166 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFKHN010000053 DAFKHN010000000
VERSION     DAFKHN010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17166
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.053"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..95
                     /locus_tag="LY912_001875"
     CDS             <1..95
                     /locus_tag="LY912_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBM6955549.1"
                     /translation="DIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            223..1437
                     /locus_tag="LY912_001876"
     CDS             223..1437
                     /locus_tag="LY912_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBM6955550.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            2426..2635
                     /locus_tag="LY912_001877"
     CDS             2426..2635
                     /locus_tag="LY912_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBM6955551.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            2747..4360
                     /locus_tag="LY912_001878"
     CDS             2747..4360
                     /locus_tag="LY912_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6955552.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            4395..5606
                     /locus_tag="LY912_001879"
                     /pseudo
     CDS             4395..5606
                     /locus_tag="LY912_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            5629..6555
                     /gene="glsA"
                     /locus_tag="LY912_001880"
     CDS             5629..6555
                     /gene="glsA"
                     /locus_tag="LY912_001880"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBM6955553.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6763..8223
                     /locus_tag="LY912_001881"
     CDS             6763..8223
                     /locus_tag="LY912_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955554.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            8444..10207
                     /locus_tag="LY912_001882"
     CDS             8444..10207
                     /locus_tag="LY912_001882"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBM6955555.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            10291..10749
                     /locus_tag="LY912_001883"
     CDS             10291..10749
                     /locus_tag="LY912_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBM6955556.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10858..11541
                     /locus_tag="LY912_001884"
     CDS             10858..11541
                     /locus_tag="LY912_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBM6955557.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            11688..12302
                     /locus_tag="LY912_001885"
     CDS             11688..12302
                     /locus_tag="LY912_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBM6955558.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            12318..12524
                     /locus_tag="LY912_001886"
     CDS             12318..12524
                     /locus_tag="LY912_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955559.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            13065..14195
                     /locus_tag="LY912_001887"
     CDS             13065..14195
                     /locus_tag="LY912_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBM6955560.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            14287..15042
                     /locus_tag="LY912_001888"
     CDS             14287..15042
                     /locus_tag="LY912_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBM6955561.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15100..17139
                     /locus_tag="LY912_001889"
     CDS             15100..17139
                     /locus_tag="LY912_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBM6955562.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFRTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRAGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFINNGTLVY
                     PKLIPDKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
BASE COUNT         5887 a         2802 c         3615 g         4862 t
ORIGIN      
        1 aagatattat cctacacttt gaaaaatacg attatcgttt tcattggaat agtgataatt
       61 cagttattga aatttggata cctattcaag attagaagca attttatatc catacacaca
      121 aagcagttag tcttaggatt gactgctttt tctatacaga tttttaatga caggcaatta
      181 tcaattatgg tagttgcctt ttttgattgg aggaattgaa gaatgaatga taaaaacttt
      241 attgaagaac taagacaaaa gcgtgaggaa tacggagtaa cacaaacaag gcttgctgtt
      301 gcctgtggta tcagccgtga atattacaac cgcattgaaa aaggaaaaca gccattgaat
      361 gacgaattaa gagaaatcat agaaaaacag attgagcgtt tcaatccgca agaaccacta
      421 ttcttattga ttgattactt tcgtgtccgc tttcctacta cggacgcatt ggcgattatc
      481 cgtgatgtat tacaactgaa atctaattac atgctttatg aagattatgg aaaatacgga
      541 tatgaaagca aatatgtact tggcgacatc aatatcatgt gttccatgca ggagcattta
      601 ggtgttttat tggaactgaa aggcaaaggc tgtcggcaaa tggaatgtta tctgctggca
      661 caggaacgct catggtatga cttcatgctg gattgtatga cggctggtgg tgtgatgaaa
      721 cggcttgatt tggctatcaa tgataaagca ggaatattgg atattccaaa gttaaaggaa
      781 aaatacaagg ctggcgaatg tatgtcctac ttccgtatgc agaaagatta cagcggtaca
      841 gaaaaatgcg gtagcgattt accaaagaat acaggagaaa ccttatatct cggttcaaca
      901 agtagcgaat tatatatgtg tgcttatcag aaaaattatg agcagtatgt caagaatggc
      961 acagaaattg aagatacgga gattaagaac cgttttgaaa tacgcatgaa gaacgaacga
     1021 gcctattatg cggttgtaga tttactgacc tatcgggacg ctgaacgcac cgctttttct
     1081 atcatcaatc attatgtccg ctttgttgac agagaggacg acaagccaaa aagtcaatgg
     1141 ataacaaatg atgattgggc atggtttgta ggggaaaaca gagagccgat acgcttaacc
     1201 acaaagccag agccttacac tttacaaaaa gcgttgcatt ggctacaaag acaagtcgca
     1261 ccaaccataa aaatggtaca ggcattagac agagaaaatc gtacaacgat actgaaagat
     1321 atgattgagc aggcagaact aaaagacaag cataaacatt tattacaatt agagaaatca
     1381 accatagaag aacgtataga taccgctgtt ccacaagaga atgacggtat tttttaatgt
     1441 aattgaaaaa tttcagattt agtcagcaaa gagctgtttt cattccctat gtgaagtgaa
     1501 agaagaaaaa taaatttttt attaaatctg caacaaaatg gctacttgcg tacagatatg
     1561 gtgcgagaaa aggaaatcta aacttttttt gaaaataggt cattaaatcg gggcttgctg
     1621 tccctatatg aagtgaaaga agaaaaaagt tttgaaaaaa tgacggaaat tcgtgattag
     1681 tggacagtct tctgtgaaaa gaggaaaaac atcatcattt tgtattcaaa caggcattag
     1741 cagttgagtg ttgatgtgaa aagatgaaaa tactttgttc tcaacttaac aatttaaggt
     1801 ttccgttccc tatatggtgc aaagaaaata tttcattcta ttgttggcag taacggtatg
     1861 gtttgggtag ttagggtgtg aaaaggaaaa tattcttttt tcatcatcaa cttagcaaaa
     1921 tgacattttc tatccctata tggtgcatga aaagaagtta aaatttttcc atttaaactt
     1981 agcaaatgga cgtttgctgt acagatagta gtgaaaaagg agaaaatcaa ccgttgattg
     2041 ccaaaatgaa ccgttccatt tgtactaata atggaaaaag ttttggattt tggttacgtt
     2101 tctcctcttt tccaacgcga tatataggaa agacgatttt tttctttcaa tcgttctttg
     2161 acaactgaat aaagctattc aatacgtttg acagacagct agccgttgaa acaaatacgc
     2221 cacgaccttt cccctgcaag agcgagcgaa aacctatttg tgttcttgta aaagatttgt
     2281 cctcttttat cgccatgacc tgtactgtca gataatgata ctcccgtaca gccacagctt
     2341 gagcattaag agcgtcgcac gcaatgggta cggctacata agaactatgc agaggtggaa
     2401 ctcctgtggg ctatgacaaa agccgttgaa ttgcttagaa agattttaca gaaagggggt
     2461 atgtgttatt gataatgctg taaaaacaat tcaaaagaaa aatggcaagt gtggcattgg
     2521 caacagagga aagacaaaga ttgtagtaaa agagcatttt tccgaaaagg gcaaaacaat
     2581 ggaagaactt ctaactgatg tcatgctgga aaaagcaaag cagacaatcg cataaaatcg
     2641 gtgcagttgt aagaaataga ttgaatgaca aaaagtaccc gtgttatact ttacttgcaa
     2701 gcaggtattg taaacacggg ttagttataa aggaggataa ctgacaatga aacaacagat
     2761 ttacaatact gcactttatc ttaggttaag ccgagatgat gaattacagg gcgaaagttc
     2821 cagcattacc acacagagaa gtatgttgcg tttatatgca aaagaacatc atttgaatgt
     2881 cattgatgaa tatattgatg acggctggtc gggaacaaat tttgacagac cgagttttca
     2941 aagaatgatt gaggatatag aggcaggaaa aatcaactgt gttgtaacga aagacctttc
     3001 ccgtcttggc agaaattata ttatgacagg acaatataca gaattgtatt tccctagtca
     3061 taatgtccgc tacatagcga ttgatgacgg tgtagacagc gaaaaaggcg aaagtgagat
     3121 tgcaccattt aagaacatca tcaatgaatg ggtggcaaga gatacaagcc gtaaagtcaa
     3181 atcagcattt aagacaaagt ttgcggaggg ggctcattac ggtgcttatg ctccgttagg
     3241 atataagaaa caccctgaca tcaaaggaaa actgttggtt gatgatgaaa caaaatggat
     3301 tattgaaaaa atcttttccc tagcctatca aggttacgga agtgcaaaaa tcacaaagca
     3361 gttaagagca gaaaaagttc cgacagcgtc atggctaaat tttacaagat acggtacttt
     3421 tgcacatatc tttgagggaa aacccgaaag taagcgttat gagtggacga ttgctcatgt
     3481 caaggcgata ttgaaaagtg aggtttatat cggaaacagt gttcacaata tgcagtctac
     3541 ggtatcgttc aagagcaaaa agaaagtgcg taagcccgaa agtgaatggt ttcgagtaga
     3601 aaacactcac gagccgatta ttgacaagga agtgttctat cgtgtgcagg agcagataaa
     3661 atcaagacgc agacagacaa aggaaaaggc aacgccgatt tttgcagggc ttgtcaagtg
     3721 tgcggattgt ggttggtcta tgagatttgg aacgaataag acaaataaaa cgccttacag
     3781 ttattatgct tgcagttact acgggcagtt tggcaaaggt aattgttcta tgcactacat
     3841 tcgttatgat gtgctgtatc aagccgtatt ggaacgcttg cagtattggg ctaaggcagt
     3901 acagcaggac gaagaaaagg tattgaacaa gatacagaaa gctggcaatg cagagagaat
     3961 acgggaaaag aagaaaaagg caagtacatt gaagaaagcc gagaacagac aaaatgagat
     4021 tgaccgttta tttgcgaaaa tgtatgaaga tagagcctgt gagaagataa cagagcgaaa
     4081 ttttgtgatg ttgtccagca agtaccaaaa agaacagata gaactggaac agcagataac
     4141 aagcctaaga gaagaactaa gtaaaatgga acaggatatg ataggtgctg aaaagtggat
     4201 tgagttaatc aaggaatatt ccgtaccaaa ggaactgaca gcaccattat taaatgccat
     4261 gatagaaaaa atcctcatac atgaagcaac aacgaatgag gataacgaaa gaatacagga
     4321 aattgagata tattaccgat ttattggaag agttgagtaa tcaacaagag taatattttt
     4381 aactaaggga aaccggcggt gtctatactt gggtcagtcg cacattggga aaacgattcg
     4441 gttttgccgc aatctttttc caatggtttg agataacagt tggctacttg accatgctgt
     4501 atttcttaac tggtgcatta tcctatgcaa cgggtattgg tgctatacaa aacaataaat
     4561 atctgaaatt ggcaatccta ttgattattt tctgggctat tttactctca cagttaaaag
     4621 gaaccaaata cacttcattg attgctcgga tcggttttgt agctggtatc ttgttgccag
     4681 cattagtctt gtttggctta gggatccatt atgtcgcttc aggcgctcca ctacaaacga
     4741 tactgtctat gaaaacattg attcctgatt tttcgaaatt gcctacgctg gttgtttttg
     4801 tttcctttat tttagcatat atgggcgtag aaacatctgc cagtcatgca aatgaaatgg
     4861 aaaaccctaa aaaggattat ccattagcaa tgtttgtatt ggttattctg gcaatcattt
     4921 tagatacttt tggcggattg accgtcgcta ctacagtacc tcaacatggt ttgtctctta
     4981 atacaggggt gattcaatcg ttagaattcc tattaagaca cattgatcca aatcttgcat
     5041 ggattgcgaa aattcttgcg attcttgttt gtttaggtgt catcggagaa attgcttctt
     5101 gggtaacctc tccttcaaaa gcacttcacg tagcagcaga agaaggatta cttcctgaat
     5161 attttgcaaa agaaaacaca cacggtgttc ctgctcattt gatgatcgca aatgggatcg
     5221 ttgcaacaat ctgggcagcc gtctttacat taagcggcgg ggggaataat ctttcatttc
     5281 ttgcagcgat gtcattgact gttgtaatct acctgatgtt gtactttatg tttttcgcgg
     5341 gctatttgaa gctggttttt aaagatgaca gtcttgaaag agcctatcag gttccaggcg
     5401 gaaaagttgt aaaagtaatc gttgcttgtt taggtctttt gacttcactt tttgcttttt
     5461 gtatctcatt tgttccacct gctagtatcg cagctggaca gcatgggatt tatgaaacga
     5521 ttctgattgt ttcttatctt atcgtcttag ttattccatt tacgatctac gcatgccgtc
     5581 ataaattcca gcatgcagaa aaataaaaaa tgaaagctgg ttattcaaat ggaagtaaaa
     5641 gaattagaac aattgattgg aaaaaatttc cactattatc aaacaggaca agtggcggat
     5701 tacattccag cattagctga agtggatccc aaacaattag gtatggcgat ttatgatttg
     5761 gatacaaaac aactgattga gggaggagac gccgatgtgc gctttgccat cgaaagcatg
     5821 tcaaaagttc ccgtattgtt attagcaatc aaagacaacg gaatagaaaa agtctttcaa
     5881 acaatcaaca cggaaccaac cggttttgcc ttcaattcta tcatgaatat ggaaatcaat
     5941 catcgcaaac atccaatgaa tccttttgtt aatgcaggag cgattgcaac aacctcgttg
     6001 attgccggta aagatgcaga tgaaaaattt gagcgaatct tgtcatttat gaaagagatc
     6061 tgtgatgatc ctaatatcac attgaatgaa gaaatctatc attctgaatc aagaacaggt
     6121 gatatcaatc gctctcttgc ttactatatg aaaggtaatc aaatgatcga aggagacgta
     6181 ccggagatac tcgatgctta tttcagacaa tgctccctca atgtcaccgc tacaggcata
     6241 gcaaaattag ctgctgtgct ggcaaataaa ggaattgctc cttggaatgg caaacaaatc
     6301 attactgaag aaagtgctac aatcgtcaaa tcaattatga caactgctgg tttgtatgat
     6361 gaatcaggag agttttccgt ccatgttggt gtacctgcaa aaagcggtgt aggcggcggg
     6421 ttgatggcag ctgtgccaaa tcgttacggc ataggtgtct tcagcccggc actagatcca
     6481 tttggtaaca gcgcagctgg tatccaattg ttgaaagatg tagtcaaaga actagacgct
     6541 gacatctttg aataaccatt cttgaaagag gctggggtaa aagtccaaac ggctcaaagc
     6601 tacctacaat gaggctgaaa ttgtgagctt gtttgacttt tgtcccagtt tcttttttta
     6661 ttggtttttg aaagggcttt tctaaataaa aaggaaacaa aaatacgatt tacagatatg
     6721 attaaataaa atcataagaa aaactggagg cgtgtatcag gaatgctgga aaattacatc
     6781 gagcgaaata tatttagaaa agtgtatctg tgtgaacaat tatttgaatt ccaagaaata
     6841 gacatcgaac aaacagctat ttctctaagg gtgactacac caacgatcct tcacgatcta
     6901 gaaagtctag ccgagtgtct agaatattgt ataaaagaac aagtaagaga gaagcataag
     6961 tataaactcg tattcaaaca tggtattgct ctttctgagc tcacacagtt tctgtacggt
     7021 caatcttatt ttttaaagtt tttaagttat tattttaatg gtatattcac gagtacagaa
     7081 ctggctgatc ttgaatttat ttctttgagt aaagtatata caatcaaaaa aatcgtattg
     7141 gattttttta aagaaaatga ttatttgaaa aataaagaaa tcattatccc agaatttgac
     7201 tcgcggaaca tcttgctagc tttagtacgt tatgtcaatt gggaaggcta tgaaaataaa
     7261 aatccgtatg tagaagaagc ttgtaacgag ttgattgatt atgtagagac tcattttttt
     7321 aaaagaagat attcggaaga tgaaaagtcc tttatcatac gagaaataga gatcgcaatc
     7381 ggaagaaagg catttcccct tggactgaaa gaagaagata agaaaagcgc agaaacgaag
     7441 ccgttatttc aattagtctg tcaaggattg gaagagcaaa aaggaattct agacttacaa
     7501 gaagaagatg tctattatat tttttctttg ttcaacagta gaaattatac caatgagaac
     7561 atggagctgt taagaaaaga tttcgaagtt gtttataaaa attttgttct caatgaccta
     7621 tcactgaatg aattgatttt acagattatt agtatcgctg aaatcgacga tgcagaaaat
     7681 tttattttca agcaatcctt tttacaattt gtccgtacgt tgtgggcaga tggacaagta
     7741 tttttaccgg aaaggatcta tcttctatca gaaaaagaac aacttctgta cggaaaaatt
     7801 gtagaaatat tggaagagtg gaaaaagaaa aatcaaatcc aactaagatg gaatgaaaat
     7861 ttcattcgaa aattcgtcaa aagtctttct ttgatcaaca gtgaacaagc ggggagacag
     7921 gaaatagaaa tttttgttgt ttcagaaagt tcagtcaaac aattttttta tcgaacccaa
     7981 tttcatttgt atgcggaaga aggcatcgct gaaataaatc ctattttatt tcgttcatta
     8041 gaagaattgc ctgatgaatg tctatgtgcg aaaaaaagag tggttttgtg cgatgctgct
     8101 agctatcaaa atggattaga aactgaaaag acaaagatct atccaatctc attaaaaggt
     8161 gcaaacatcc atttgtatca tattgctcag gaacttcacc tattaaaaaa acatatttct
     8221 tgatgagacc ttaattagga gaccttctac aaagcttttt aattgtctgt agaaggtttt
     8281 tatttgagtc ctgattcgtg cgaagatcta cttatataac aagctttctc tgaaattttt
     8341 ttaaaatgct attgacttag agtcaactct aagtagtaga atagataaag tgtaacaaat
     8401 ctattttcat taaaagaaga tagtacggag gagagaatgt attatgagta cagtattaca
     8461 tgtattggat gcaatcaata gccccgcaga tgtcaaaaaa ttatctgttg aggaaatgaa
     8521 acagttggca gaagagatgc gccaaaaaat cttgcaaaag gacagcgatg taggtgggca
     8581 cgttggtccg aatctaggtg tagtagaatt aacgattgcg tttcattatg tatttgattc
     8641 accaaaggat aaaatcgttt gggatgtttc ccatcagtct tatggtcata agcttttaac
     8701 tggtcgaaaa aatggttttg aaaaaggaca ttaccgtgaa gtgagcggat attccaacca
     8761 acatgaaagt aaacatgact attttacagt ggggcacaca tctacatcta tcagcttagc
     8821 aacaggttta gctaaagcga gagatctgaa gaaagaatca ggaaatgtgg tagcatttat
     8881 cggtgacggc tccctaagtg gtggcttagc ttttgaagga ttgaacaatg gtggtgtttt
     8941 acaatccaat ctaatcgtat tagtaaacga taatgagatg tctattgatg agaatcatgg
     9001 cagtttatat aaaaacttag ctgagcttcg tcaaaccaac ggtaaaagca gcaataacct
     9061 atttaaagca atgggatttg attatcgtta cgtggataat ggaaacgatc tggaaacggt
     9121 gatccgttta tttgaagaag taaaagatat tgatcatccg attgtacttc acgtccatac
     9181 ggaaaaaggt cgcggttatc agccggcaat cgataataaa atgaaatatc attggcatgt
     9241 accatttgat ctgtccaccg gggaggcaaa gcaagtaact tctggagaaa catttaatat
     9301 gatcatcatg gattatttgg ataagaaaat gcaaacaagt acagctccta ttgccgcagt
     9361 caatgcagcg ataccaggcg cctttggact gaaaacattc caagaaaaac atccagatca
     9421 ttattttgac gtggggatcg ctgaacagca ctctatcact ttcgcttctg ctttggcttc
     9481 tcagggagta cgtccagtcg tcttccaatc aagtactttc ttgcaacggg catatgatca
     9541 attatcacat gatttagcga tcaacgagaa tccagtgatt attttagtcg gtggcggaac
     9601 gatctcagct agtgaccgaa cacaccaagg aacatttgac attccttact tatcaagtat
     9661 cccgaacatc aaatatcttg ctccagcaac aaaagaggat atgatctcta tgctagattg
     9721 ggcgttcgaa caaacagcgc agcctgtagc aatccgaatt cctacacatg gtgtagaaca
     9781 tggtacagct atcgcaaatg attatagtat tccagcctat caaacagtaa ataatggagg
     9841 aaaagtagca attttagctt taggcggttt tcttgaatta ggaaaagaaa cagtaaaagc
     9901 ttttagaaaa aaaggaatcg aagcaacgtt gatcaatcca ggaacgatca cagaaaatga
     9961 cgtagaaaca ttagataaat taaaagaaac acacgaatta gtcatcacat tagaagatgg
    10021 tagtttgtca ggaggatttg gcgaaaatat cagtcgttat tatggtgatt cttcaatgaa
    10081 cgtattaaat tttggtgcag agaaagaatt cacggatagc gttcctgtag ggcagcttta
    10141 tgaacgttat catttaacac caaaacaaat cgttgaagat agtctgcgtg tcttgaatat
    10201 tcaataattc attatgctca ccatccagat aattgtttat actagtatct ggatggtttt
    10261 ttcattataa aaagcaaagg ggtggatgtt atgtatcagc aagtagaaga atatgtcaaa
    10321 aagttccaag aaaaatatcc tagttatcaa tcagaaaaat taggtttctt ttcatttggg
    10381 gatacagaaa aaatggcaga cgagttgagc gaactagttg taaaaaagat aaagactggt
    10441 acatcaagtg gttacgatct gtataaacaa gagaatgagc ctttaccaaa agttggtcaa
    10501 ttagacgtgg tcctgaatgg aaaaaatgaa ccagtttgta tcatcaaaaa tataaatgtg
    10561 accatcttgc cttttagtga agtcacgaaa gagcatgctt ggaaagaagg agaaggggat
    10621 cggacattag cttattggcg gaaagtccat gctgagtttt ttaaacatgc ttataaagaa
    10681 gcgttgaaca tagaatttac agaagagaag ctggtcgtat acgaagaatt tgaagtaatt
    10741 ttcttttagt aagaaaggtc tgctgaaaga aatagctcat tattgtctcc tgaatagaaa
    10801 agggttacat ttttatatga agctgtattt ttatataaca ttactggagg agatattgtg
    10861 gatacactgg aacaaatcaa aggcggagtc gtcgtttctt gtcaagcttt ggaaaacgag
    10921 ccgctacaca gttcttttat tatggggaga atggctttgg ctgcaaaaga aggcggagca
    10981 gttggtattc gagcaaatac gacagaagat atcaatgaaa tcaagcgaat cgttgattta
    11041 ccggtaatag ggattatcaa aagagattac gatgggtcag aagtgtttat tactgcgaca
    11101 gaaaaagaag tggaagaact tttggagacg caagcagaaa tcattgcact ggatgcaact
    11161 tctcgtaaac gtccgacaga aaaaacaact gctgaacttg tccaaatgat tcacgaacac
    11221 ggtcggttag ctatggcaga tatttcgact tttgaggaag cgcttcaagc gcaagaagat
    11281 ggttttgatc ttttgtctac gactttagca ggctatacag aatattcacg aaagacgcag
    11341 acacctgatt ttgatttatt gaatcaaatc atagaacaag tcgatatccc agtaattatg
    11401 gaaggacata ctgactctcc tgaacaagta gagaaagcat atgaattagg tgctttttca
    11461 gtcgtagttg gatctattat cacccgtccg caattgatca ctaaaagata tgtcgaagcc
    11521 gcaagtaaag caaataacta aaaaacacgc acggcacaga ttcttgacaa aaaagaaaaa
    11581 ttgatagata gtttaaagca gattctaaga agatgaaaaa agcattactt ttcattttgt
    11641 cttcaagatc tgctttttaa cgaattttat agaaagaagg cgaaaccatg tttgaacgga
    11701 gtccttcaga attgacagaa cgtgaaaatt acaagttgct gattggttca gtcatcccta
    11761 gaccagtagc agtagtaacg actaaatcag caaaagatat agtgaatatc gcacccttca
    11821 gttacttcaa tatcgtcagt tcgaatcgac ccatcttatc cttggcgatc cagagaaaac
    11881 aagatgcagt aaaagacaca gcaaagaata ttcttgagac aagagaagct gttatccata
    11941 tccttgatga ggacaacgta gaagaagtaa ataaaacagc agccaatctg cctaatgagg
    12001 aaagcgaact gtacctgact gacttgactt taactgattc agtaatcatt tcagtaccag
    12061 cattgacaga agcaaaagtt cgttttgaaa catccttata tgaacatgtc gagatacgga
    12121 ataaaaataa agtaacagct gatttatttt tgctagaagt acagaaatat catttaaatg
    12181 aaacagtcta tgatgataag acaggaagga tcgatccaag aaaattgaat gctgtaagcc
    12241 gtttggcagg aaatgattat gcagcaatag gagaaatttt cacgattgca cgtcccgaat
    12301 aaaaaggagc actagttatg ttaaaaataa gctataaacc atcgacagat tcaaaagaaa
    12361 tgaaaaaaga atatgaaaca gtgaatgatt ttctgcaagg gcagtactta gaagttccgc
    12421 cattgcaaga ccattttgtc gttactactg ttactttaga tggtaaggaa atagaaatgc
    12481 cagatcaaac gattagcgga ttgtttaatt actttaacaa ataaatattt attccgaaaa
    12541 gtgaaaaaac atataaaaaa acacataaaa ctaaaaaatt atcaaagaat cctggtgcaa
    12601 ctgaaagaat ttgcaacggg attctttcaa cttatttgtt atttttttct aaaaaatatt
    12661 aaagattgtt aaatttcact atttcatttc aaattccatt gcctaatcat taggaaaagt
    12721 ctataatgaa ctcgtaaata gaatatagta ataaccttgt taggtgaggc tcctatacaa
    12781 acataggctg ttgcccagaa acgtcgaaag tcgccaatgg gtaaaacaga aactgttgga
    12841 ttaaggcttt ttccaatagc taagaatgtt ttctttacgt tgtatagtgc taaaactcgg
    12901 acgatgagat gatgctaggt cagaattctt gttcgaaaag gtttctgacc ttttctttat
    12961 atttttgtga ctgacttatt tgatgagaca aactcgctcc tcacctgaca agtggattgc
    13021 tgtgtgagga ggagatgcgg tgaaaaaaga tcgattggtg gattttgggt ccttatttga
    13081 ctttgtccat gatcggtctt ttagaagtat acagtgccag ttcttatcgt ttattgcaag
    13141 ccgatgaaaa tacaaaaagt ctattattgc gtcaactaat tttcatattt ttgagttgga
    13201 gcgtgatctt cttagctcgt tcagtcaaac tacactattt acttcaccct aaaatagcag
    13261 gatacggttt agccttatcg attttctttt tagtattagt aagaataggg atattcggtg
    13321 tcactgtcaa cggcgcacaa cgttggatct ctctgtttgg cattcaattc cagccttctg
    13381 aactggcaaa tctttttttg attttttatt taagctggtt ttttcgtgac ggaaatagta
    13441 gcccaaaaga tctaaaaaaa ccattcctga ttacagtagg tataactttt ctgattttat
    13501 ttcagccaaa gattgctgga gcattgatga tcctttcgat tgcgtgggtc atattttggg
    13561 cagcggcggt tccatttaaa aaagggatct atctaatcgt tactttttct gcattgctga
    13621 ttggagcagc aggcggggta ttatatttag gaaataaagg ttggcttcca cagatgttta
    13681 atcatgctta tgaaaggatc gcgactttaa gagattcttt tatcgatagt catggtgcgg
    13741 gctatcaaat gacccattcg ttttatgcac tatataatgg tggcatattt gggcggggat
    13801 taggaaatag tatcacaaaa aaagggtatc ttccagagac agaaacagat tttatttttt
    13861 cgattattac agaagagctt gggctaatcg gtgcattgtg tgtgcttttc ttattgttct
    13921 cattatgcat gagaatcttt tgtttaagca gtcgctgtaa aaatcagcaa gctggattgt
    13981 ttcttttagg attcggaact ttgctattcg ttcagacgat aatgaacgtg ggaagtatcg
    14041 cggggctgat gccaatgact ggtgtgccat tgccatttgt tagctacgga ggaacaagtt
    14101 atctgatcct ttctttagga atcggaatca cgttgaatat ttcttcaaag atacaggccg
    14161 aagagttggc gctctatcga cctgaaaaac aataaagaga aactgagaaa ctctcagttt
    14221 gaattatcat aaagtacaat cttttatttt tcaagcgaga ggttctttta gaaagaggaa
    14281 ttcgcaatga aagtatctca aaaaatcata ttatctattt tgttactgct tacattagta
    14341 gttggctatt tttcgattga gtttatccat ggattttcgt ctgcaaaaca gagttcaact
    14401 gtgaaaaagg tagagccgaa aagtatccct accacactaa atgtggcttt gattggttca
    14461 gatgctcgtt cgaaagacga aaacggtcgc tcggattcac ttctggttgc acaatacaac
    14521 cagaaaacac aacaagcaaa actgatctct atcatgagag attcatatgt cgatattcca
    14581 ggttacggaa tgaataagat aaatgcagct tactcttatg ggggagttga tttattaaat
    14641 caaacattaa aggaaaattt caaatttgaa gctccctatt atgcaagtat cacatttcaa
    14701 gattttatcg attgcgttaa tgaactgttt cctggtggag tcaagatcga tgcagaaaaa
    14761 tctctagatt tagatggcgt atatataaac aaaggagagc aagtgatgga tggtaatact
    14821 ttactccagt atgctcgatt tcgggaagac aaagaaggag acttcgggag gatcagaagg
    14881 cagcagcaag tgatcaaagc tatctctcag cagctgaaag acgtaacttc aatattcaag
    14941 ctacccaaag cggttgggaa attacttggt agtatccaaa cgaaccttcc agaaagtgtg
    15001 cttctggatt gtggtatgga tttcctcaaa gacatatgtt agaataaaca ggtataaata
    15061 gtgaaataaa ggaatgacaa gcaagagaag gaggaaaaaa tgaaaagaag tgacaagcac
    15121 ggcaaaaatc gaacaggcgc ttatattgcc ggcgcagtga tcttaatagc agctgcgggt
    15181 ggcggttatt tttactacca gcactatcaa gaaacccaag cagtagaagc tggagaaaag
    15241 acagttgagc aatttgtcca agctttgaac aagggagatt ataacaaagc tgcagaaatg
    15301 acatcaaaaa aggcggcaaa taaaagtgca ttatctgaaa aagagatctt agataaatac
    15361 cagaatatat acggtgctgc tgatgtcaaa ggacttcaga tatcgaatct aaaagtagat
    15421 aaaaaagacg attctactta cagtttttca tataaagcaa agatgaatac ctcattaggt
    15481 gaattgaaag atctttctta taaaggaaca ttagacagaa atgatggtca aaccacgatc
    15541 aactggcaac ccaacttggt ttttccagaa atggaaggaa atgacaaagt aagcctgacc
    15601 acacaagaag cagcaagagg gaatattata gatcgaaatg gtgaaccatt agcaacaaca
    15661 ggcaaactaa aacaattagg agtcgttcca agtaaacttg gagatggagg cgaaaaaaca
    15721 gccaatatca aagcgattgc ttcctccttc gacttaacag aagatgctat caatcaggcg
    15781 atttcacaaa gctgggtaca acccgattac tttgtcccat tgaaaatcat tgatggagca
    15841 acgccagaac ttccagctgg agctaccatt caagaagtag acggcagata ttatcctttg
    15901 ggtgaagcag ctgctcagct gattggttac gtgggagata tcacagcaga agatattgat
    15961 aagaatccag aattaagcag taatggaaaa atcggtcgct caggtttgga gatggctttt
    16021 gataaggatc ttcgtgggac aacaggtggg aaattaagca ttacagatgc agacggtgta
    16081 gagaaaaaag ttctgatcga acatgaagtt caaaatggca aagatatcaa attgacaatc
    16141 gatgcgaagg cacaaaaaac agcttttgac agtctaggag gaaaagctgg atcaactgtt
    16201 gcgacaacgc caaaaaccgg tgatcttctt gcgcttgcta gctctccaag ctatgatcca
    16261 aacaaaatga caaacgggat ctcacaagaa gattacaaag cttatgaaga aaatcctgaa
    16321 catccattca tcagccgatt tgcgacaggt tatgctcctg gatctacgtt taaaatgatt
    16381 acagcagcaa tcggtctcga caacggcact atcgatccaa atgaagtgtt gacgatcaac
    16441 gggcttaaat ggcaaaaaga cagttcttgg ggatcttttc gaacaacgcg tgtcagtagt
    16501 gatgtatcac aagtagactt aaaaactgct ttgatctatt ccgataatat atatgcggca
    16561 caagaaacgt tgaaaatggg tgagaaaaaa tttcgtgcag gcttagataa attcattttt
    16621 ggtgaagacc ttgatttgcc aattagtatg aatccagcac aaatttctaa tgaagatagc
    16681 tttaactcag atatcttgct agctgatact ggatatggac agggcgaact tctaattact
    16741 cctatccagc aagcagcaat gtattctgtt tttatcaaca atggcacact tgtctatcct
    16801 aaattgattc cagataaaga gacaaaagat aagaagaatg tcatcagcga aacagcagta
    16861 caaacgatcg tgccagatct gagagaagtt gtgcaagatg taaatggtac agcacattct
    16921 ctttctgctt tagggattcc gttggcagcg aaaactggta cagcggaaat caaagaaaaa
    16981 caggatgtaa aggggcaaga gaacagtttc ttgtttgctt tcaatcttga taaccaaggt
    17041 tatatgatgg tcagcatgtt ggaaaataaa gaagatgatg attcagcaac caaacgagca
    17101 tcggaactat tgcaatacct caaccaaaat tatcaataaa aaattgcttt ttaagtacag
    17161 taaaag
//
LOCUS       DAFKHN010000054        16556 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFKHN010000054 DAFKHN010000000
VERSION     DAFKHN010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.054"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(26..724)
                     /locus_tag="LY912_001890"
     CDS             complement(26..724)
                     /locus_tag="LY912_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBM6955563.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGGSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(717..2069)
                     /locus_tag="LY912_001891"
     CDS             complement(717..2069)
                     /locus_tag="LY912_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBM6955564.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2292..3692)
                     /locus_tag="LY912_001892"
     CDS             complement(2292..3692)
                     /locus_tag="LY912_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBM6955565.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3853..4590
                     /locus_tag="LY912_001893"
     CDS             3853..4590
                     /locus_tag="LY912_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBM6955566.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4715..5194
                     /locus_tag="LY912_001894"
     CDS             4715..5194
                     /locus_tag="LY912_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBM6955567.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5191..5958
                     /locus_tag="LY912_001895"
     CDS             5191..5958
                     /locus_tag="LY912_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955568.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6188..6757
                     /gene="lepB"
                     /locus_tag="LY912_001896"
     CDS             6188..6757
                     /gene="lepB"
                     /locus_tag="LY912_001896"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBM6955569.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6861..7463)
                     /locus_tag="LY912_001897"
     CDS             complement(6861..7463)
                     /locus_tag="LY912_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBM6955570.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7569..8038
                     /locus_tag="LY912_001898"
                     /pseudo
     CDS             7569..8038
                     /locus_tag="LY912_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8144..8728
                     /locus_tag="LY912_001899"
     CDS             8144..8728
                     /locus_tag="LY912_001899"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBM6955571.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8731..9804
                     /gene="prfA"
                     /locus_tag="LY912_001900"
     CDS             8731..9804
                     /gene="prfA"
                     /locus_tag="LY912_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBM6955572.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9797..10636
                     /gene="prmC"
                     /locus_tag="LY912_001901"
     CDS             9797..10636
                     /gene="prmC"
                     /locus_tag="LY912_001901"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBM6955573.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10629..10808
                     /locus_tag="LY912_001902"
     CDS             10629..10808
                     /locus_tag="LY912_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955574.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10830..11855
                     /locus_tag="LY912_001903"
     CDS             10830..11855
                     /locus_tag="LY912_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBM6955575.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12030..13274
                     /locus_tag="LY912_001904"
     CDS             12030..13274
                     /locus_tag="LY912_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBM6955576.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13427..14374
                     /locus_tag="LY912_001905"
     CDS             13427..14374
                     /locus_tag="LY912_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBM6955577.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14508..15137
                     /gene="upp"
                     /locus_tag="LY912_001906"
     CDS             14508..15137
                     /gene="upp"
                     /locus_tag="LY912_001906"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBM6955578.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15276..15518)
                     /locus_tag="LY912_001907"
     CDS             complement(15276..15518)
                     /locus_tag="LY912_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955579.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15639..15711
                     /locus_tag="LY912_001908"
     tRNA            15639..15711
                     /locus_tag="LY912_001908"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15672..15674,aa:Thr,seq:cgt)
     gene            complement(15830..16468)
                     /locus_tag="LY912_001909"
     CDS             complement(15830..16468)
                     /locus_tag="LY912_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBM6955580.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT         5643 a         2951 c         3330 g         4632 t
ORIGIN      
        1 tgtcacattc ccctttttcg aataactagg ctgtttgtcc ttcaagatag ggcagatcca
       61 attctttacc gtaacgttgt tctaaagcta ggcggatcaa acgagctgcc aggttctcat
      121 ttcttgcaag gataggtcca tggaaataag aaccgaagac atttcggtaa atgacacctt
      181 cagattggtc ttcaccatta tttccttgac cttgtaccac tttccccaaa ggtcgttcac
      241 cttcacctaa gaaagtccga ccattgtggt tttcaaatcc ataataagtt tcattgaatt
      301 cttcgttatg gataacgata tcaccgataa accggttatt ttcctgactt aacgtgtagt
      361 gatccagtgc actgattcct tggatctttt ctccattagc tcccatgtag tagtgaccta
      421 gcaattggta gccaccacaa atggctaaca tgacgccatc attttcgata tagttgatca
      481 aagaatcttt ctttttctgg atgtcttttg aaatgattaa ttgctcaaag tcttgaccac
      541 cgccaaagaa aaccaagtca tatttatcag catcaaaagg ttcatgtata ctaacgatct
      601 ccgtatggca agaacccccc attttttctg ctatatattt caacatcaaa aggtttccgt
      661 tatcaccata tgtgttcatc aaatttccat aaaggtgggc gatattgagt tcataattag
      721 ccacggttca ttcctccttt gataaatcct tgagcagcta gttctttacg aagctgcaat
      781 acagcagtgt aagtagctaa aatatagaca tgctcagttg gcaattcttt gattttttcg
      841 attacttctg gtaattcttt tgtttctgtc aatttatttt ctggaatccc ggcaactttt
      901 agacgtaaag tcatatctgt atgacggtct cctccagaaa taacagctgg gatatccata
      961 tcggcaaagt tttcaaaatt accatcccaa atccagctga catcgattcc gtctgcgtaa
     1021 ttggcattta ataaagccac taaagaaaat ggataaggag ctagaccaat catatcgatt
     1081 acttgattga tacctacagg atttttgaca agtactaatg tacatttttt cccattgata
     1141 ttgatgactt cttgtcggcc gaatactttc tcgtcatatc ctaaaccttg tttgatttta
     1201 tcaggatcga cattgaagta ctctgccact gcagtagctg ctaaagcatt gtagacatta
     1261 tacataccgc caacttcgat tccgtattca tgaccatcga tcacgaaatc tgctgacaca
     1321 ttgtccatcc gtaccatatc agttaatcga taatccaatt caggacgttt gaagtcacaa
     1381 tttggacagt aatatttccc taagtttgca taagtgatca ttttataatg caagatgtga
     1441 tgacaatttg gacataagac accgtctgta ttgtaatgag ccatttgttc acgatcttct
     1501 tcatggtcaa agccataata ttttctagga ttgactgttt cgatagaatt gaagattggt
     1561 gaatcaccgt tactgataat cgttgcattt ggtgactttg cggcaccgtc tacaatcatt
     1621 ttataggtcg tatagatttc tccataccga tccatttgat cacggaaaat atttgtaaat
     1681 aagaacagtt ctggtttcat atattctgtg actttgctca aacttgcttc atctatttct
     1741 aggacagcaa actttttctg tccttttttt ggttttgcct gcaagaaagt cgatacaatt
     1801 ccctgtacca tattcgcacc agtagggttg gttagaactt catcgaattg ctggcgcaaa
     1861 atattgactg ttaaagcggt agtcaatgtt ttaccgtttg ttccggtgac aacgacgact
     1921 tggtagtctt ttgccaaact atctagtata tgtggatcga ctttcagcgc tagtttacct
     1981 ggtaaacttg atccgccttt aaaaaaagtt tttaatgccc attgcgacgt ttttccaact
     2041 gcaatcgcaa aatgactgcg tattcccatt atgtaacctc caaaaacgat ttgctgacga
     2101 ataaattcaa ctaatcatac catatgttga aaaaaaggtt aaattgcttt tcttattctt
     2161 aagaaaaggt tacggctgaa agtgcatgaa atcggacaaa atcgcatgat ttaacaaaaa
     2221 aacagcttga aacaaaatga ttgtttcaag ctgctgtgat tttattattc cctcttacct
     2281 atattcccat tttaaccgat aataattttc tcgcttggat attcatagcc tagatctcgt
     2341 gtttcttttg gcacgaataa catcaatgta tatagcattc cgatccgccc aataaacatc
     2401 agtgtagcaa tcgtgatttt gcccacaaca gacaagtctc cggtaatccc taaagataaa
     2461 ccagttgttc caaacgcaga agttacttcg atgatgatcg agatcagcgt ttgttcttct
     2521 gtagcagata aaaaaacgat acaaaagaaa cacataccaa gagaaagcat aaagacaacg
     2581 actgattttc gcacatcatc ttgatcgatt ctccgtccaa aaatattgat gttatcttca
     2641 cttttgagga aggaatatag atacaaaccg atgattgcta cagtagttgt tcgaatcccg
     2701 ccgcctacag aactaggact gcatccgata aacatcagta aagaaaaaat gatcagtgtt
     2761 gtgatttgaa aatcacccaa atcgtgaatc tgcagaccag cattacgagt cgtaatcgaa
     2821 taaaacatcg aattgatcca tttgacactc atattggaat cttggaataa atggtccttt
     2881 tccaatagat aaatcaagac agttcccgaa acaaacaaga taacaaaagc taacacagct
     2941 aatttggtaa acaaggaaaa acgaaacgga agcttcgcat tggaacgttt gtataatagc
     3001 cattcccggc actccatcaa tacaggaaaa ccaattcctc cgacaaaaat caaaaacatg
     3061 atcaggatca agaaaaaata gtcatgtgca aagggcttga tggaatcccc agtgacgtca
     3121 aacccagagt tcgtgacagc cgatatcgcc tgataaaaac cgtaaaaaac ggcatcacgc
     3181 caacgatcaa aatagcctct gtaataaaaa taaatagaaa agaatgtccc aaaaagtaat
     3241 tgaaaccaga ttaaaatagc aaaagtgatc cgaatcagtc ggacgatacc agacaaacgc
     3301 ggttgattca tatccgtcat gatcagctgt cgctgtttca gtgtgatccg tcgtttagaa
     3361 aaaatgacaa aagcagtaga aatcatcatg atccccaaac caccaacttg aaataatatt
     3421 tccagcagta taataccgtt atcattgaac acagaattga tatcaaaagt cgatagtcca
     3481 gtcacactca ctgtactgat tgccatgaac agcatgtcca caaaagaaac atggctatct
     3541 ggttcgcgaa aaatcggcat ataaaataga acgagtgata agaccgtcat caatatataa
     3601 taaaaaacga tgatttggat cgatgagaaa tgattggcag caaacttctg tcctcgccgc
     3661 tgcagccttc gaaagaataa atcaacatgc acagtactat cctcctgaca atagtcgttt
     3721 ctaccagtat acaaggggaa ttaggaatac tcaaagaaat tatcaaacag ataacaatac
     3781 agctttcgat taaaatagaa atggcttata ataaggaaaa tcctagaaaa aagaaggagg
     3841 aggaataaca aattgattaa tgctcaacaa atcgtagaaa aaatgaaaaa tcaaaaaata
     3901 aattatgata cagttctgaa aaaaatgatc atgcaatggg agaaagaaga agtaaagcct
     3961 aagatattaa tacatacatg ctgtgctcct tgcagtacgc acacattgga attcatgtct
     4021 caatatgcag agatcacgtt atttttttca aattcgaata ttcatcctaa aagtgagtat
     4081 ttgcgaagat tacatgaaca aaaacgattt gtagaccaat ttaatgagaa aactgaccat
     4141 catgttgcgc taatcgttga tgaataccgt ccaaatgaat tcaccaaaat ggttttaaca
     4201 aaccatcttg aaaacgaaaa agaaggtggt gctcgctgca gtgcatgctt caatatgcga
     4261 ttagatcttg ttgcgcaaaa agcgcaagaa ctaggatacg attactttgg aagtgccctg
     4321 accatctcgc caaagaaaaa tgcagctttg atcaatcaga tcggaatgga tatccaaaag
     4381 atttacggga cacaatactt gccaagtgat ttcaagaaaa acaaaggcta tgaacgctct
     4441 ttgcaaatgt gcaaagagta tgatatttat cgccaatgtt attgtggttg cgtgttcgct
     4501 gccaagcagc aaggatgcga tctgaaagaa atcaatcggg aagcaaaagc ttacttaaaa
     4561 acatcaaccg tagtttttga ggaaaattaa agaaatcttt cggaaaaacg taagaaaaaa
     4621 ataaagaatt tatggtagaa ataaggtaga ctgtataatt tgtccgtagt aaagtaagga
     4681 aacaagaata aatttcaatg aaggaagaga taagatgcga aaagtagcac ctattttgaa
     4741 gccaatcgct gtattaacaa tctcgacgat tgtcgcgact actacaggta ttgtgaatag
     4801 ttccagctac cgtgcaccaa gttcaagttc tagtactgta gaagaaacaa caccaactac
     4861 ttcagtctcg acatctgaac caacaacaac ggaaagtttg aatgaaacca ctacgacaag
     4921 tacatgggac gatacaacaa ctagttcgtc gtatgatgag acatatacaa ctgacagctc
     4981 aagcgaaaca agtaatacgg taccagatgg cactccatcg gattcaacca atccaagtac
     5041 aagtccggat acaagtgcta gctccgaaac gataccaagc agtacgactg tagatgataa
     5101 cacgcaaaat gatgatgcag cacgtacagc acagcaaaac caagattcag gaaataccca
     5161 aacgtataac cagcaagcag gtgattctca atgacatttt tactagacct tatcaacggg
     5221 gtgcataaat tccttggcta tttagacatc agtcctaaat atcttaaccg tggatatacg
     5281 attttaagtg tgattcccac gctttattta ttgagaattg tttatggact ttggcaaaac
     5341 caaaactatc ttcaattttt cttatatgga cttgcatttc tagtgcttgt ttattttact
     5401 gttttaaatg tattttatta ctttttagat aaaaacacga aagccgatgt cactcagctt
     5461 tttgtgaagt atttacctga tgaagcgttc aacatccaga cagaagaatc gatagataat
     5521 ggaaattcga tcgataaagt gaatacacaa gaggtcatgg tttcttatga cgaagattat
     5581 caattgaaat tagccgagaa tatgcggtat ttgattggaa atggtgagat caaaacaaat
     5641 gaactcggtc gcatggatgg atttctggtc gatagaaata cattgtatcc ttattactat
     5701 gtcaagaaaa caggagagaa agagtatgtt ctaaatattg gacgaagcta ctcggacatg
     5761 gaaaaagtag ggaccattcg acttgactca acagaagaca cattggaacc tgtcggattg
     5821 ttcatcgtcg gcggtgattt tgtcaaagac gggttacgct atcatgagcc ttatcgtctg
     5881 aaattgattg caaaaaaggc acagtcgcag gaagaaccag tggtttatag tcgtagccaa
     5941 agaagaagac attcataatg tgatgaaacg ccgtgtatca gtggttgcga taaaaacgtt
     6001 tattcggaat aagggggatg tgacacgtct tttgtcacgt tcctttttta tataacgaga
     6061 aagataagac gaacacatca cttattcttt cctttcattt ataaacattg tagaataaag
     6121 aaagtacaac gaagtattgt gaaaaaacgt aataaataac gaggaaaata caagtaggag
     6181 gtaagctgtg aaagaatttt tgaaaaattg ggggattttg atccttgtat tagcggctat
     6241 tttattagct agagtgtacg tgtttacacc agttactgta aacgggcatt cgatggaccc
     6301 tacattaagt gatggacaac gattgatttc atctaagatc tcaaactatg aacgaatgga
     6361 tattattact acaaaggaac cgggggatga agaacggatg attgttaaac ggatcatcgg
     6421 tatgcctgga gatacagtca agatggaaaa tgaccagttg accattaatg gcaaaaagta
     6481 tgatgaacct tatctggatg agttcaaaaa agaattttca gaagataagt tacaaggaga
     6541 atatgcttat agctcaggat tccaagcaca agcagaaagt tcatccacct ttacgagtga
     6601 ctttgaatat actgtgccaa aaggaaagta tcttgttcta ggcgataacc gcttgatttc
     6661 aaaagacagc cgaatgtttg ggttagtcga caaagatatg atccaaggaa aagttgtttt
     6721 ccgttattgg cctctttcag aaattaaaat catgtgatga aaaaataaaa agaagctgtg
     6781 acatgttttt tgtcacagct tctttttccg aaaattcctt cttatttctt ggagttgctc
     6841 actttttttg caatctcatt ttaagctttt tggctgatgg ataagaaaag cgaagcgttt
     6901 ttgttcataa atagcttttc cccacgatgg aaggtatgac tagtagcaga gacaaagccc
     6961 gttttttcca atcgattatt caattcttct tggctaaagc cattatggac tttcggatga
     7021 ctaatttgtt cattcttgtc aaagtctacg atgatcaatt gaccgccagg agctaaaatt
     7081 tcataaagtt ttgtaagaat attctccgta tcaggaatgt gtaaaagtac aagtgataga
     7141 aggatgagat tagcttggac agcaggaaat tcgacagaag catcagcgtg gatcgttcgg
     7201 acatttttca gatctgctgc ttggatcttt tcttctgcca ttttcagcat agtttctgaa
     7261 gcatcggcaa tgatcagttc tttgaatctt tccgcaagcg gtaaactaac aagcccagtt
     7321 ccgcctccgt aatccagcag gactttttgg tggctgtcgc gcggtagata agtagttagt
     7381 tcttcgcgaa taatcttggc taatgcttga cggtcagggg aatcataatg gttagcgatg
     7441 gaatcaaaaa tattttttgt catcaaatag ctccttacgt aaaactttga aattttaact
     7501 tattatagca cgtgaaaaga aagaaagcat gctatactca attcaaaaag ggagaatcta
     7561 gaaagaatat gccgatatcg tttgtaaaag atagagagga aaaaggaaag tgtgtccgag
     7621 aaatattact agacttgcct gagtggtttg ggcttcctga atcaacggaa aaatatatcg
     7681 aggaatcaag taaactacct ttatggtgtg aaaaaagaaa agaagaatat ttaggcttta
     7741 tcactctttc acagacaagt gaagatactg ccgaaatcta ttctattgta tgggaataaa
     7801 aaaagactat catcaccaag gattaggaac aaaacttttt aaagaagcag aaggttacgc
     7861 agcaaaacat tacaaatatt tgcaagtgaa gactgtagac gaggggcact actctatata
     7921 tgatcaaact atttgtttct acgaatcatt aggattttca aggttggaag tttttccaaa
     7981 tttatgggat gaatggaacc catgtttagt tcttgtcaaa aaattggaac aaaagtgagc
     8041 aatagattta atactaatct gtgcttgatg aaaattctca ctgtaaaaaa tgctgaaaat
     8101 caagtataat accataggaa caaactggaa ggtgaaaaag agcatggcac aactattttt
     8161 taagtatggc gcaatgaata gcggcaagac gatcgagatc ctaaaagtcg cacataatta
     8221 tgaagaacaa aataagccag ttgtcttaat gacaagcggt attgatacaa gagatggttt
     8281 aggcgttgtt tcaagccgaa tcggactgaa acgtaatgcg atgccgatat ttgaagaaac
     8341 agacgtattt gacgtaattc agaaaatgga aagcaaaccc tattgtgtgc tgatcgatga
     8401 agcgcaattc ttaaaaaaga aacatgtcat tgcttttacg agaattgtgg acgaattgga
     8461 tattccggtt atggcatttg gtttgaaaaa tgattttcga aacgagttat ttgaaggatc
     8521 aaaatattta ttgctttatg cagacaaaat cgaagaaatg aaaacaatct gttggttctg
     8581 ccacaaaaaa gcaatcatga atttacatta tattgatgga aaccctgttt atgaaggcga
     8641 tcaagtgcaa attggcggaa atgaagctta ttaccccgtt tgtcgaaaac attactttca
     8701 cccatcaatg attacagaag gagaataagc atgtacgatc aattacaagc aattgaagac
     8761 cgttatgaag agcttggaga acttttaagt gacccagaag tgatttctga tacaaagcgt
     8821 tttatgcagc tttcaaaaga agaagcaaac acgcgcgaaa cagtcgaagt ttatcgtcgt
     8881 tataaagaag tagtacaagg aatcaccgat acagaagaac tgcttggtga aaaactggat
     8941 gatgaaatgg ctgaactagc aaaagaagaa ttatctgaat taaaaaaaga aaaagaagtc
     9001 ttagaagaaa aaatcaagat cttgctttta ccaaaagatc caaatgacga taaaaatatc
     9061 atcatggaaa tccgtggagc agcaggcgga gacgaagcag cattattcgc tggcgatctt
     9121 ttcaatatgt accaaaagta tgctgaagca caaggctgga aaacagaagt gatggaagct
     9181 aacgttaccg gaatcggtgg atataaagaa gtgatcatga tgatcaccgg agacaacgta
     9241 tattcgaaat taaaatatga aagtggtgcg caccgcgtcc agcgtgttcc ttcaactgaa
     9301 tcgcaagggc gtatccatac ttccaccgca acagttgtcg tgatgccaga agctgaagaa
     9361 gtagagatcg atattgaaga caaagatatc cgtacagata tctatcatgc ttcaggtgct
     9421 ggcggacagc acgtcaataa aacagcatct gctgtacgtt tgactcactt accaacaggg
     9481 atcgttgttg ctatgcaaga tgaacgttct caaatcaaga accgtgaaaa agcaatgaaa
     9541 atcttgcgtg ctcgtgtgta cgataagatc cagcaagaag cacaaagcga gtatgatgcc
     9601 aatcgaaaat cagcagtcgg aactggggat cgttcagaac ggatccggac gtataatttc
     9661 ccgcaaaatc gtgtgactga tcatcgtatc ggattaacta tccaaaaatt agatcagatt
     9721 ttagcaggga aattagatga gatcgttgat gcattgatca tgtatgatca aacatcaaaa
     9781 ctggaagcta tgcaaaatgg gtaaaatgac ctatcgagaa gtcctgtcac gggcttcttc
     9841 ttttttagag gatcatggga aagaagcata tagtatccaa tttttatttt tggaacgaaa
     9901 acaatggaaa aaacttgatt ggctccttca tatgaacgaa gagatttcag aagaagaaca
     9961 gcggttgatc gaaaccgatc tgcgacttct gcttgcagat catccacctc agtatttgct
    10021 aggatatgca gatttttatg atcatcggtt aaaggtaact gaagcaacac tgatccctcg
    10081 accagaaaca gaggagttag tcgaatggtg tttagacgag acgcctggtg taccgttaga
    10141 agtgatagat attgggacag ggactggagc aattgctatt agtttgaaag cagcaagaaa
    10201 aaattggcat atatctgctg tggatctttc agaagaagca ttagaagtag cgaaagaaaa
    10261 tgctcagaaa gaaggaacga aaatcagttt ttatcatgga gatacattag gaccagtaat
    10321 ggatcagcaa tttgatgtga ttatttctaa tccgccgtac atcagtcgga atgaatggga
    10381 actgatggat gaaagtgtcc ggtcattcga acctaaaatg gccctttttg ctgagaacga
    10441 tggattagct atttatgaaa aaatagcagt tgaagcacca agcgtactaa aatcaaatgg
    10501 aaagattttt ttagaaatcg gatttcgcca aggtgaagca gtaaaaaaaa tatttcagca
    10561 agcatttcca gataaaaaag tggcgataaa aaaggatctt tttggcaatg aacgaatgat
    10621 ccaagtttat ggttgaagtt gtggatgaaa aattttttat ttgttttttt attataaaaa
    10681 aacacttatt tgacaaggat gtaaacgact ttttggttta tcaacaagtt tatccactat
    10741 tgacaaatag attatccaca aacagtggaa aacttgagga taaactcaga caaaataaga
    10801 atgtatgaaa aaggggttgt ggataaactg tggaaacgaa acgatatgat gaaacagaat
    10861 tgcaagaggc agccgaagca ctgaaagaag gagaacttgt tgcttttcct accgaaacag
    10921 tatacggatt gggcgccaac gctcttttac caaacgctgt caagaaagtg ttttctgtaa
    10981 aagggagacc gcaagataat ccattaatcg tccatgtcgc ctcttttgaa caagtaaaag
    11041 agtatgtgga caactttcat ccggcagcag agaagattgt gaagaacttc tggcctggac
    11101 cattaacttt gatatttaag atcaaaaaag acactttgcc ctcagttgtg acgggaggat
    11161 tatccacagc tgcatttcgt ataccggata acaaaaaaac actagaagta atcgaacttt
    11221 ccggtgttcc gcttgtcggt ccaagtgcaa atacgtcggg aaaaccaagt ccaacgactg
    11281 cagatcatgt atatcatgat ctacaaggaa aaattaccgg gattattgat gatggagcta
    11341 cgcgaattgg tgtagaatcc actgttcttg atttaagtga tccaacagcc atgcctatga
    11401 ttttacgacc aggtgcagta acgaaagaac aaatcgaagc agtcatcgaa tctcctgttg
    11461 ctattgatca gcatcttgta aaagaaaatg aaacaccaaa agcccctggg atgaaataca
    11521 aacactactc acccgataca cgtgttctga tggtcagaga tggcgattgg tcaactgcag
    11581 ttcaatgggc aaaaaataag aagatccgtg caggtgtcat agcaagcccc gaaattgcgg
    11641 atcaagtgcg gacagatact gcagctgttt atatgtataa cgacaactca gtagaagcgg
    11701 cggctaaagg attgtttgca ggtctaagag gattagatga accaacactt ggattagatt
    11761 tgatttttgt acaagtgtat ccagaaactg gattggggaa tgcttacatg aatcgcttga
    11821 aaaaagcagc aggacaaaat tattttgaaa aatgatcaat tggttattgt cgcattcttt
    11881 tagtatgata caatgctatc aagtaaatct tctatcagtg aacgaaaaac taagcgtaac
    11941 taatcgtaat agaagagata cgaatatttg gcaatttgtt tttgatggga aaaataaaat
    12001 tgtaggaaaa taaaaaggag ctgttgtttg tggtagatta caaaacgttt gaccctgatc
    12061 tttgggctgc gatcgccaaa gaagaagaaa gacaagaaca taatttggag ctgattgcct
    12121 ctgaaaactt tgtctccgaa gcagtgatgg ctgcacaagg aagtatcttg acaaataaat
    12181 acgcagaagg ttatccaggg catcgctatt atggtgggtg tgaatttgtc gatatcgttg
    12241 aaaatttagc gattgaccgt gcaaaagaat tattcggagc gaaatttgcg aacgtccagc
    12301 ctcactccgg ctctcaagcc aacacggctg cttatctcgc tttggtagaa ccaggggaca
    12361 cgatcttagg aatggatctt tccgcaggcg gacatctaac acatggatca ccagtcaact
    12421 tcagtggcaa aacctatcac tttgttgctt acggtgttga tccgacaaca gaagttattg
    12481 attataatgt ggtacgtatt ttagctagaa aacatcaacc aaaattgatc gtagcaggtg
    12541 ccagtgctta cggacgaacg atcgactttg cgaaattcag agaaatcgca gatgaagtag
    12601 gcgcaaaact gatggtagat atggcacata tcgcaggatt agtagcagca ggacttcatc
    12661 ctaatccagt tccttatgca gatatcacaa cgactaccac tcataaaaca ttgcgtggcc
    12721 ctcgaggcgg catgattttg acaaacgatg aagcattagc aaaaaaaata aatagtgcgg
    12781 tatttcctgg tattcaaggc ggccctctag agcatgtgat tgcgggtaaa gcagtagcat
    12841 tcaaagaagc attagatcct gcatttaaag aatatagtga acaaatcatc gccaatgcaa
    12901 aagcaatggt caaagttttc aatcaagcaa ttggaaccag agtcatttca ggggcgacag
    12961 ataatcatct gatgttgatc gatgttcgcg agttaggtat aaatggaaaa gaagcagaga
    13021 gcattttgga cagtgtgaat atcactgtaa ataaaaactc gattcctttt gaaacactaa
    13081 gtccattcaa aacaagcggt attcgaatcg gcacgccagc aatcactact cgcgggttca
    13141 aagaagaaga tgctgtaaaa gtggctgaac tagttgtcaa agcattacaa gcaaaagatg
    13201 ataacgctca actagacgaa gtcaaaacag gtgtacgcga attaactgaa aaatttccgt
    13261 tgcataaaaa ataaaaattt aaattccatt agtaaacaga aaagttcaat gttgggcttt
    13321 tctgtttatt ttttgggaaa acggattctt tgacaatatc ggtgatgctc tctagtatat
    13381 gaggtgtaat tttagtcttc acactaaatc tcagggagga aaagtcatga ctgatcgtat
    13441 ctcgttagaa aaggaagcag tagcattcag tgatgcaaat gcgcctcatc cgcgtatcta
    13501 tgaactagca ccggaagaag gaagagtttt actagaagaa gtacaagaat cacctgtgaa
    13561 caaatattcc gtcgatattg aagacttgat ggtggatact ggcgaatggg gaaaactcaa
    13621 tattcgtctc gtacgaccag aagggaatat ggataaatta ccagttattt tttatattca
    13681 tggagcaggc tgggtttttg gcagtgctca aacccatgat aaattgatca gagaacttgc
    13741 ggttcgtacg aattccgtcg ttgtctttcc agaatatagt cgatcaccag aagcaaaata
    13801 tccaacagca attgaacaaa attatgctgt gttgcaacag ctgaataaat tagccaagtc
    13861 aaaaaatctg gatctcgaga atctaatcgt tgcaggagat tcagtaggtg gtaacatggc
    13921 tacagtcatg acgatcttaa caaaagaacg aaagggcctc ccaatatcca agcaattgct
    13981 gtattatcca gtcacaaacg ctgattttga tacagattcc tatcatgaat tcggagaaaa
    14041 ctattttttg acaagagaag gaatgatgtg gttttgggac caatatacga cgaatgaaga
    14101 agagcgtgct gaaatcacag cttcgccttt gagagcaaat ataaatgaac taaatgatct
    14161 tccttcagca atgattttaa cgggagaagc ggatgtatta agagatgaag gtgaggctta
    14221 tgcgcgcaaa cttcgtgatg caggggttcc tgttacacaa gtacgcttcc aaggaatcat
    14281 ccatgatttt gtcatggtaa atgctatgga tcagacaaag gcaacgcgtg cagcaatggc
    14341 attatctact tcttggatca agaaaaaaga ataagctttg cttgtccgca ggaaaacttc
    14401 ttttcaaaaa cggattttct taggaaaaat ggcgagtttg actagtcaat cacttgattt
    14461 tgttttacaa ttaaaaagaa acgacagaac aaaggagagc ttaaaaaatg ggcaaatttc
    14521 aagtgatcga tcatccattg attcaacaca aactaactat tattcgggac aaaaactgcg
    14581 gaacaaaggt ttttcgtgaa gtagtcgatg aaatcgctat gttgatggca tatgaagtat
    14641 cacgggatat gccattggaa gacatcgtga tcgaaacacc gatcactgaa acaacacaaa
    14701 aaacgttgtc tggtaaaaaa gtagcgatta ttccaatctt gcgcgcaggt attggaatgg
    14761 ttgacggtat cttggaattg attccagctg ctaaagtggg acatatcggt ctttatcgag
    14821 atgaagaaac attggaacca catgaatatt tcgtcaaact tccagaagac attgatgcac
    14881 gtcagttgtt tgtagtagat ccaatgttgg caacaggcgg atcagcaatc atggcaatcg
    14941 atgcattgaa agaacgtggc gcgtcgaaca ttaaatttgt ttgtttggta gcagcacctg
    15001 agggagtaaa agctttgcaa gaagcgcatc ctgatattga catctataca gcttctctag
    15061 atgaaaaatt gaatgaacat ggttatatcg ttcctggact aggggatgcg ggtgaccgtt
    15121 tgtttggtac aaaataagta aatacgaaaa agggtgtgac acaacttttg tcacatcctt
    15181 ttttggtcat ttttaacgtt tgatgcagaa cagctttttc acagctttcg tttgcatata
    15241 aaaaaaccat cccaaaaatg cagagatggt caaattcaaa tcttttttag ttctttgtag
    15301 ttaacgatta ctacaccctt actttgcgtc atcaagttcg cattttctgc agtttcatca
    15361 atctcaacaa cagcggaatt tttcaattgc tttgaaatcg ttccagtttg cgacttgccg
    15421 tgaattgtga acattacgtg agtattgatc ttgaattttt caccaatttc cgatggtacg
    15481 atagttgtat caaattttcc aaaagttgcc attttcataa aacctgcctt tcacatcaat
    15541 tataccacgt tttatgaaaa atatcatgaa attaaactaa ttttccatcg gactctttac
    15601 aatcagccaa atagagtata taatttcttt tggataaggc cagcttagct cagttggtag
    15661 agcaacgcac tcgtaacgcg taggtcgtag gttcgatccc tatagctggc attaaaagag
    15721 aagacagata tatcaaggat ttttaatcca ttgatacatc tgtctttttg tttaaaggaa
    15781 ataaagtatg ctttcttagc aatagagcat gtattatttc tataaaaatt taggagaata
    15841 aaacgactag caatatagct gtgaaatcaa atatcacatg aactgcccaa cttgtaatga
    15901 tcgagttgct tttaatggca gcttggttga ataacaatct tgccacccct tgtatcaaaa
    15961 ggatgtgtgc tacagtgtgt aaaatatttc cattatcata agtactgtaa tggataaatc
    16021 caaagatgat tgctgacaag aaactagcga caggaatgct gaacttacta gaaaaaatag
    16081 cgagaaaata cactgagaac aattcttctc caagtatcat gataggcaaa ataataaata
    16141 ataacgggct gaaagcctca tttattggat tgcctgttaa accccatttc aaaatttgtt
    16201 gcaaaaatac cgagactgcg gcactgatta ctacattgat aaaaaaatat ttggctatat
    16261 ttttgacagg agcgacaggt ttcgagaaca tttttttcgt atctttttta ccaaaaacaa
    16321 gtgtaaatgc tataaatcca gtgatagtta aagaaaaaat gctaataatg gatggcgcaa
    16381 atagcaaccc taacaaaccg agtacaacga caatagtgcc caatatccct tttttaagtt
    16441 ctattttttt tcctaaaatg ttattcatga taataactcc tactattcag tttttgaaga
    16501 tagagtcagt atacatgaag agttaaaata ggcaatgttt ttttatggat atttgt
//
LOCUS       DAFKHN010000055        15423 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFKHN010000055 DAFKHN010000000
VERSION     DAFKHN010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.055"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..492
                     /locus_tag="LY912_001910"
     CDS             <1..492
                     /locus_tag="LY912_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955581.1"
                     /translation="IFSLSKDDKIVMGKRIREVRKNREETLEKFGKNFTIYTGKNVIS
                     RWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDYKNILPKDERVSDFKKINSFSMGLR
                     MRKIRKDYYLEREEFGKLFSPSISKWSIDRYENGRDIPNTNRIIQYAYIGNLSLEFLI
                     YGI"
     gene            1488..1739
                     /locus_tag="LY912_001911"
     CDS             1488..1739
                     /locus_tag="LY912_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955582.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            1822..2094
                     /locus_tag="LY912_001912"
     CDS             1822..2094
                     /locus_tag="LY912_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955583.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            2184..2423
                     /locus_tag="LY912_001913"
     CDS             2184..2423
                     /locus_tag="LY912_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955584.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            2570..6853
                     /locus_tag="LY912_001914"
     CDS             2570..6853
                     /locus_tag="LY912_001914"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBM6955585.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            6952..7317
                     /locus_tag="LY912_001915"
     CDS             6952..7317
                     /locus_tag="LY912_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955586.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            7319..7771
                     /locus_tag="LY912_001916"
     CDS             7319..7771
                     /locus_tag="LY912_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955587.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            8385..9695
                     /locus_tag="LY912_001917"
     CDS             8385..9695
                     /locus_tag="LY912_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBM6955588.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            9718..10029
                     /locus_tag="LY912_001918"
     CDS             9718..10029
                     /locus_tag="LY912_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955589.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            10390..11646
                     /locus_tag="LY912_001919"
     CDS             10390..11646
                     /locus_tag="LY912_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBM6955590.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            11643..12188
                     /locus_tag="LY912_001920"
     CDS             11643..12188
                     /locus_tag="LY912_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955591.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            12189..12689
                     /locus_tag="LY912_001921"
     CDS             12189..12689
                     /locus_tag="LY912_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955592.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            12770..13326
                     /locus_tag="LY912_001922"
                     /pseudo
     CDS             12770..13326
                     /locus_tag="LY912_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13346..13690
                     /locus_tag="LY912_001923"
     CDS             13346..13690
                     /locus_tag="LY912_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955593.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            13709..14620
                     /locus_tag="LY912_001924"
     CDS             13709..14620
                     /locus_tag="LY912_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBM6955594.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            14699..>15423
                     /locus_tag="LY912_001925"
     CDS             14699..>15423
                     /locus_tag="LY912_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBM6955595.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAK"
BASE COUNT         5394 a         2265 c         3309 g         4455 t
ORIGIN      
        1 atatttagtt tatcaaaaga cgataaaatt gttatgggaa aaagaatacg agaagtccga
       61 aagaaccggg aagagacgct tgaaaaattt ggtaaaaact ttaccatcta tacaggcaaa
      121 aatgttataa gtagatggga aaaaggtatt aatattccag atattgaaaa actaatgaat
      181 attgcctatc ttggtaaggt cactgttcct taccttatgt acggagaaga ttataagaat
      241 atacttccaa aagatgaaag agttagcgat tttaaaaaga taaattcttt tagtatggga
      301 ttaaggatga ggaaaattag gaaagattat tatctagaaa gggaggagtt tggaaagctt
      361 ttttctcctt caatttcaaa atggtccata gataggtatg agaatggtag agatataccc
      421 aatactaatc gaattatcca atatgcttat ataggaaatc tttctttaga atttttgatt
      481 tacgggatat aaaaatagtt tacgtcgata cttattaagt tatcgacgtt ttttattata
      541 gaaaaaattt ataaaaggag gtttcttgat atgataagaa acaaaaaggg tttgttgaaa
      601 gttgctttac tggcagcttt tttctaagta actttttgac aagctcaatg gcaacacaag
      661 cggaagaagt aatacaagaa ctaactgtta tgaataacag ctagataaaa tgggctatgt
      721 atgttatcca acaatttagt aatcactaga agcctagcga aagttcgctt gataagttat
      781 agatgagtat tgatttgtag tgtttccaaa tcaaaagggt acagagccac atgaaatatg
      841 ttgtcctctg cagcgtcagg atgggaatcc ataccatgga gattcggaga tctgtgaggg
      901 aatacttacg tggttaatat gtcagttgtg ttggacgtag taatggtcat agtgggtaga
      961 ttgactgaat tcttatatga gaaaatgaaa ccaacaagaa gatagggtta tttatacaga
     1021 attggggatc ttttctggaa aagtaatcgg ataatgcgag attcgtacgg tcttttttaa
     1081 atttctctaa aaaaaacggc atcgaatggg ttgggtgatt gataagcaat gaatcataga
     1141 ctgatataga ataaaaaatg attctattta tctttttaca tctatcgttt tttcaagtag
     1201 ccgcaaatta tatcagcatt caacaatttt tgtatacaag ttctagtaaa aggatctgaa
     1261 gaaaaagttg gttgttgtga agataaaaaa agaatcaggt tttactgagt ttttcttcaa
     1321 aatttgtgtt attaggttag gacaaagata agaagaagta tgaagattta aaaaaggaat
     1381 gaggaaaaga tagtaatttc cgattattgg agttttttta tttataaaga agaagcgaat
     1441 aagttgtgat tcctagattt cgcgcgtgat taattaatga gcaaaaaatg cggaaagttt
     1501 tagtgtttaa tacacgagga caaagtttct taggtattga aggcacacgt gtaacggttg
     1561 atgggtggtg tgattgtttc gaggttggaa aacatgttga acttatggca tttactgagc
     1621 taaaagataa gaacaacgtg gaatttttcg agagtgatat tggttgggac gatcatgaag
     1681 aagtttatgg aaaatttatt ttgcggaagg gaaattctta tacgaatggg gaagcataag
     1741 tagcgatttg ttagagatca ttgataggat tgaaattgtc gggaatattt atgagaatct
     1801 agagttattt gaggtgatag aatgagtgat ggttttgaac aagtatcaat aattaaaaat
     1861 caagttcggg agattcttag aaaaaaaggc tatttggtag atagttattt tgaaggagat
     1921 tacgaaacat gggtaggtgt ctatgctcgt ccagagaata aacctaccta tttagatcct
     1981 acgacgtcag aagatgccta tttacaaaat aggtatcgag tagatggttt taagcaagac
     2041 tttgcggagt ggtttgaatg ggaaattgaa aacggagaag taaaagaaga ataagagtac
     2101 ttgttgtatc aaaataagcc agtagaacaa ccaaaccagt agctagtaat gacaataata
     2161 ctgaggaatc ggatcattat ggtatgattg atatttctct tccagaagat cttaagccag
     2221 atcctgtaac aattggcaat agtgtcatga tttttgattc attagatgaa gctatgtcat
     2281 atggttggaa agaaattaag gatgaaggta gtaattggta tggcatgaga tttggtgatg
     2341 gtgaagttgc caaaaaagct ggtattccaa ttgggaaatg gacagttgat ttccacgaag
     2401 caggttcttt ttttgttctg taattatagt gggagggtaa aatcattgat gaaatgtgtt
     2461 cagataagag cgccagataa aaatagaaga gacagttcac gtcgttatca cttttggtaa
     2521 cggcgttttg ttttattata taaaattctc aggaaaagga ggaattcttg tgtatgcaaa
     2581 aacgaaaatg aattggttga aagcactcgc attggtggct ttttctcaat tctgtttctt
     2641 ggtgggaact gctcaagcac atgcagaaga aacgacggct atacaaccta cgatggaagc
     2701 cattgcccaa gtcgcttctg aagtgacaga agtccaacca gcagaagccg gggtcccagc
     2761 tggtgaagcc actgttgaac aggcccctgt gacagaagcg ccaacggtca attccaaaac
     2821 gactctcgat cagacgattg gggaaacaca acacccaggg aatagtcctg gtacttcaca
     2881 accagttgaa gaaactgcct caattacaac ccctgcttca gaaacgtcca ctctagaagg
     2941 agaaaaagct gccgaagcaa cgccttctgt gcagccagag tcttctgaga aacaagcgga
     3001 agaaaagaaa cgaatagaag aaacagtgga acaaccagcg gctactgctg acaaagaagg
     3061 aaaaaatgag gaaaacgttg aaaaaacaat ctcttcaacc gcagctagtc aaaatcaacc
     3121 aacgaaacca aacaaagaat ctacggctag tattgaaaat caaaagaaaa aagagcagaa
     3181 cattccaaaa acaggtacac ctacactgtt agtaacagta ccaaccaatc gttcggttcg
     3241 tgttcgccgt gcaaccaatg cagctgtttt aggtggtcgg aaaattgatt ggggcgaaaa
     3301 tattggtgtt acttctagtc cgaacaatct aaacttcact ttaaattata tggttcgttt
     3361 tgagattaat ggacaagtgg cgttttgtat tgagcctggt gtctcagccg cagaaggtca
     3421 agtttataca gctactgctt tgaaaaacta tttgaaaaat tcaaatgtac ggaaaaaaac
     3481 aagcttgatc tcttatttag gatatgtcac aaataaagac aaatccgatg aacaatacat
     3541 tgcggcacaa tttatgattt gggaagcttt gggcacaaaa atcccaatca aaaatatacg
     3601 tgttgattat gatcgtcgaa aagcagaaat tcaacgtttg attaataact ttggtgaaaa
     3661 agcaactttt aataatcaaa cacatacggt aaaaattggc gaaacgttga aagtaaagaa
     3721 taaaaatgat tttttgaaat atgtgaaaga cattcaaaaa ccaaaaggtg tcaatgtatc
     3781 tattcacggc aatgaagtat ggattacagt cacaaaagag gcaccggata aagcaaaaat
     3841 tcaattgaat aaaattaaag ttcaaggtgc gccattagcc tatcgtcgtc caggagctca
     3901 aacaattggt gtgttacatc caacagaacc taatgcgtct gttattaatt tacaaattct
     3961 aaaacaagga aacattcgtg tgtttaaaga agatgcggaa actggtgtga aagcacaagg
     4021 tgcagcttct ttagaaaatg cggtctatgg tttgtatcaa gcagatggga aaaagattaa
     4081 agaaattacc ttgaaaaaaa ttaacggcaa agtacaggca gaaattaaag atcttgatcc
     4141 tggcaaatat gttttaaaag aaatcaaagc gccaaaaggt tatgtgcttt ctgatgaagc
     4201 aattgaaatt gttgttgaac ctggaaaaac tgtcaatgcg accgcaaaag atcaagtgat
     4261 caaaggaacc attgatttag tgaaagttgc taataaagat ttagtcgatt caacgaatcc
     4321 agataacaaa ccaaaattag ctggcattga aatcactttg acgtcaaaaa caactggcaa
     4381 agtggtgaaa accgttgtga cagacaatga tggttatgct acttttggta aaaataccgt
     4441 tgtctttgat acgtacattc tttctgaaac caaaggaaaa gaagggtata aactatttga
     4501 accacttgaa gtcacaattt ctgaaaatgg gcaaactttc cattatgttt tagaagataa
     4561 agtaattgaa caacgtctta aagtggtgaa agtggatcaa gaaacaggaa aagtgattcc
     4621 acttgctaat acagaattca agatttttga tactttagcc aatcgttatg tcacaatgga
     4681 gattccaaat gatacagaaa caacggatat ctttaaaacc aatgaaaaag gctttttcct
     4741 aactaacggt acacttactt atggaaaaga tcgctatcgt ttggaagaaa tcaaagcccc
     4801 cgtaaattac gttttgaatc aaaacccatt agtgttctcg attaccaatg atacagaacc
     4861 gatcaaagtg atccattttg cgaaccgtca agcacggaaa agtgtaaaat tattcaagta
     4921 tgaagaatgg aacaagaaga aaacgccgct cgcaggtgtg aactttacct tgtataacgg
     4981 taaaaatcaa gcaattggtg aatataccac tgatcaaaac ggggaaattt tagtgaaagg
     5041 tctagttgcc gatgactatt acttcttgga aaatgcccca ttagaaagtt tccaaccaaa
     5101 tacagataaa caagcattca cggttgcatt caaacaaaat gcgccagatg atggggaaac
     5161 gttagtggtt tctgtacgta attacttgat tccaccaaaa ctagaaacac aagcgtcaaa
     5221 taaagccgat ggtgaaaaag tggttgatcc attagaaacg atcgtcatta aagacagtgt
     5281 ttcttatacc aacttgtttg tcggaaaaga atacaccatt tcaggagtat tgatgaacaa
     5341 ggcaacgaat gcgccaattt tacaagatgg caaagaaatc acaagtacct tggcctttat
     5401 tgcagacaaa gtcaatggca caaaagacct tgaatttgtg gttaatgcta gtgttctgaa
     5461 aggtcaaacg atcgttgttt ttgaaaaact tttccgtgat ggcattgaag ttgcagcaca
     5521 tgcggatatc aacgatgaag cccaaagtgt gaaagtgaat aatccaaccg ttcataccac
     5581 ggctgtcttt gaagacggat tgacagtcgc agacccaaca ggattgttta ccttaaacga
     5641 taccgttgaa attaccgaga ttcttccagg aaaagcatac ttggtcaaag ggatcttaat
     5701 ggataaagca accggtgaac ccttgcttgt gcatggaaat acggtagaaa cgagtgttgg
     5761 ctttattgcc aaagcagaaa atgaaacggt gatcgtacca tttacctttg atttgacagg
     5821 tataaatggt cgtgaaatcg tcgtgtttga aagtcttttt agaaatgatg aagaactagc
     5881 aaaccataaa gacatcaacg acaaagggca aacggtacga gtaactaacc caagtgtacg
     5941 tacaacggct acacataaac ccactggctt gaaagaggtt aatccattaa cgaaagtcac
     6001 cattacagac gctgtgaaat accacgattt ggtcgttgga aaaacataca cagtcaacgg
     6061 tgttctaatg gacaaagtaa cggaaaaacc agtgctagta gatggaaaag aagtcacaag
     6121 taccttaacg tttgtggcag aaacaacgga tggtacagtc aatctagact ttattctaga
     6181 cgcacgtgcg ttgcgaggca aagaagtcgt ggtctttgaa gatctgttta gagaaggcgt
     6241 attattggct tctcacgcag atattaccga caatgaccaa accatcaaaa tcagtaatcc
     6301 aaccattacg acgaaagcga cgaataaaaa tggcggaaaa gagatcttgg ccttgccaaa
     6361 tcaaactgtg cttgaatggg tcaaagtaga cggtcttgcg attggtcaaa tctatcgctt
     6421 aattgttcaa ggctacttaa caccagacgg cacaccattt gaaggcactc atgcggaaaa
     6481 agtctttgcg gccgataaag aaatgatgga attcttattt gaattcttag tggacggtcg
     6541 caatcttgca ggaaaaggct tgagttttgc ggaatggctc caagcgaaaa cggaagatga
     6601 gaaagaaacg tttgaagaag tggcgaaaca caatgtagat ctaacaaaca aagatcaaac
     6661 ggttcaaatt gtggaagcgc caaaaccacc gcaaccagtg aaaccagaac aacgggttaa
     6721 accagctact gttgtaccaa tgttgccaaa aacaggtgaa caaacaagta gtatacttat
     6781 ggttcttgga ttagtagtat tagtcattgc tttaggtata acactttata aagtacgtaa
     6841 agccaaagat tagtcatgag gaacaagcgg ttaggatttt taaccgcttg tttgattgta
     6901 atgtagaaat atttagaatt tattttggtt tttaagagga ggaaaaactt tatggcagaa
     6961 aaagcattgc gtatgaagaa agagttttta ggtcaagtat ttttattggg ttcacgggaa
     7021 cctaatccac caaaggaaat taatggtgtg tctgggcgat atgttcaatt acaagcagag
     7081 tgttcgcgag aagaacagcc tgcttttttt gtttatctca cagctgaaga ggataaaaga
     7141 ttacgattac cagaaaaaga ggtgcgtatt tcatttgaag aagcttattt tgtttttcgt
     7201 aaagaacgag tgaatagtcg tgaaacaaat gatatgggac aaacagagcg tcgaacaact
     7261 ggctatcaag atgttggtgt ctttttaact ggtgtaaaaa ttggggaggt tttgtaagat
     7321 gggattaaaa tttccaaata attatgacat tacagaagca ttagatgaaa cttgtttagg
     7381 agccgtacgc tttggcgcat tagaagagtc tgatcgtgta tttgataatg aaacaggcga
     7441 ttatacggga gaaattcgat cacagcgagc acaattagtt tttggaaatc cagatgaacc
     7501 aaagattgca cgacgagtta aatttccagc agatgtagat ttgactggtt ttaaacgacg
     7561 tgatcctgtg aaattaattg atccagaata tcatgtggta tatattccag cacaagatgg
     7621 caatcgtgaa tattcagatt tagtgattta tgcgaaagga ttagagaaag tagaagctcc
     7681 aacaaataat cctaatatga aacaatcaca agaaaaaggt ttagatcaaa aacaaccaag
     7741 tgttgattct aaggaaaaag agaaaaaata aggttttttt gaaagaatag gaaggagtct
     7801 tcctattctt tttatctaag atagaaggaa ggggagattt tgaattcaga taaaaccaat
     7861 caaatacttt gagagattgt gcttgttatc aaaatatcca acaattgatt gagtattttg
     7921 gagacaatcc aacgattttt gtacaaacaa atgcatatat ttgtgcggtt attgggcagt
     7981 gtatgttttt acgtgatctt gttcgttttt cattaccgta ccagtggaaa caagatcatc
     8041 aggaagtgat ttggattcgt atagtacgaa tatgtaatat gtgtgcacac ccttataaaa
     8101 atcgattaaa tctttttcga ttatgttttt ttactaaatg tgatattcct gtattagttg
     8161 ctttttgtca aaagttttta gcacaggaaa agtaaaaaca gaaaggagga atgtgacaat
     8221 tgaaagctca ttttttcaag tatcgtggtc ggcgaattcg ctatttcaat cgttatttat
     8281 ggttttgcta ttatggtttc tttttgtttc catttttgat tctgttaggt tggtttagtt
     8341 ggaaagtatt ttatccacgt ttaagtacgt tttcgaattg gcaaatgtat cttattcctg
     8401 gaataagtat tgtgttgtat ttgttgctgg ttagtgggtt aattttaggg ttgatgcatt
     8461 ggtcgcgact aaaagaagga tattttgcct ctgtttattg gcgtcagtta cttgttcgaa
     8521 tgttaattga caatcggttt gtttatacaa agaaacaagt tagtgagaaa caaacaaggg
     8581 aaaaaatgag attaccaaaa gtttattttt atcaaaagaa acaagaatta gtggtttctt
     8641 ttcctttaga tggtgggcgt tttcacgaac gatttttaaa aatgggtcat ttgttatctg
     8701 aagtattttt gcgtgattta attcgtgaag aacgagaaaa agcccgaatc aattatgtat
     8761 tcctttcaga ttctggtcgg attcctattg atcaatgtat agcagaaaat ggacgtattc
     8821 atttaatgaa aactttggat tgggtatatg atcaatcacc aaatatgttg attgctggtg
     8881 caatcggtgg tgggaaaacc tatttattgt attctttaat tcaagcttgt ttaagtgttg
     8941 ggacagtaga tatttgcgat ggaaaagcgg cagatttagc agcattaggt gacgtcgatg
     9001 tattcaaagg acatgtgttt tacaaaataa atgaagaaat gattatttgt ttacgaaatg
     9061 cattaaaaga aatgaatcaa cggtatgcct atatgaaaac catgaaagat cctaaatatg
     9121 aaccagggaa aaattatgct tattatgggt taccaccgca ttttatcttt tttgatgaat
     9181 gggcagcttt ttatggttcg ttggatatgg aagcgagaaa tagagtcgat aaattgattc
     9241 agccattagt attaaagggt cgtcaagcag ggatgtacat tattttagca atgcaacgac
     9301 cagatgcaga atattttcca agtggtgttc gggataattt aacattccgt atttctgttg
     9361 gtcgattgtc tcccattggt tatttaatga cttttggaga agattttaaa aataagccat
     9421 tttacaacaa agatcaacct ggtcgtggat atgcttttcc aggatttgat gtacctgtag
     9481 agttttttgc gccatttgtt tacaaagatt atcactttat caaagaattt gagaaattta
     9541 ctgaaatgat tgtctatgat tttacagtaa aagaggatag tcaagatcaa acgatgggag
     9601 atgataatca gttgttacaa gaacaactag agcgccaaat gtatttagca aaagatccaa
     9661 aaggaacaag tttttctgat gcgcatattt tgtaatcaac taaggaggtg aagttaaatg
     9721 gcagagagtt gttattatag agtagctaca gcaatacgaa tgattaatcc ttctctttct
     9781 tccagaacgt tttatgattg gttgaatcgt attgaacaag taactgatta ccgctttttg
     9841 cgcaaagaac gtgtttttac aggaaaagtt attaatcaag tattgctaac gaaaaaagat
     9901 atagaacgat tgactcgatt gtatcattat cgagtagatt tagaagagga tttaactttg
     9961 tcaatttatc gcgttttttc tcctgaaaaa tatagtgaaa taacaaaatt agatcattta
    10021 attttgtagt tattatctat cgggagggct ctagacgtag tctggtagcc gcactctgcc
    10081 tggcggtgcg cattaaggct gcgaagcatg ggcctataat gcgcactcgc tagcagcgtg
    10141 tgcagctcac aaagaggtcg tgcgcttgcg cacggcctct ttgtgtaaag ccccccgata
    10201 tataatatgg ggggcagaaa taacataaca catagaaaaa agttttataa acccttttgt
    10261 atcaagtgat tatctaaggt cagcagttgt actacttttc ccaaaaaacg agggggacta
    10321 gttgatatat cggtgtttct aaagggttaa aaaaaatcga ttttgttatt ttataaaagg
    10381 agcgagaaaa tgacaccgat tgagctaaaa agctacagaa agaagttaag tgcaattcat
    10441 aatataagtg gagataaaaa gccgctatca caagcaagat ttgcgcaatt gatgggctgc
    10501 tcaaaagatt acattagaaa gatggaacaa gggaaaagaa aaatcccaga ggattttgaa
    10561 caacgaatca aggaacgctt tcgattgtat atgaaaagcg gaatagatct tcgagcaatg
    10621 attgattatt tgcgtctttc cttttttggg acagactaca aaacagtgat tcaacgtgta
    10681 ttacgaatgg atctgacaga atttgaaaca cgtccaacgg gcttgtatct ttttgactgt
    10741 ctttctgttc gtgggaatat ctgggtgttc tggcattcaa aacgaactgt aacagaaaat
    10801 gtacttgtgc aattttcagg acaaggttgc cgggaatatg aggaagtcat gcgtgaacaa
    10861 caaacagatt ggcgaacatg gctatattcc atttggaaaa atcaaggaaa gttggaagct
    10921 ggttatacac gtgtgcaatg tagccgattc gatattgcgt tagatgaact ttggggattg
    10981 gaaacggaag aacatttcga tctctttgaa ttactagaaa aacaaaaagc aggtttatta
    11041 gaaatggact ttaagagatt ccagaatatt ggcggttgtt ttttagatga tggctatttt
    11101 cgaagtgaag gattatcttt gtattttgga tcgcgaaaga gtcctctctt ttttaatttt
    11161 tatgagaaac gttttgaaat tgcgaaccga gaaaaaattt cagaattaga agcattaacg
    11221 aaatatggta tttataatcg atatgagtta cggttagcca atgagaaagc aacacaagca
    11281 gtagaagcat ttattttagg tgattcaccg aaacgtttag gagagattgg cgttggttta
    11341 attaatgcaa aacttattgt ttgggataga ctggaaagtg atgcacggat tgttgataaa
    11401 cgatgggcaa aattatttcg ttcgatggaa gaattggatt ttacagtaaa gccagaaaaa
    11461 ttctcattag atcgttcaga acgctggttt ttgaaacaag tagctccgac attaaagttg
    11521 ttacaagaag cagatcgtat tttaggaaga gactttgtac aagaagggat tgataatgcc
    11581 gaactaaatg acgagcaaca aaactatcta gaatggatgg gaacgtcagg agggaaaatt
    11641 gcatgaatgc atatacgaca acagaatggc tgcgcctgtt ggatttaaag gctgcaatcg
    11701 aagcattaaa tgaaaagatg gttgatttgt cttattttcg ttttcgagtt ccttatattg
    11761 aacaagcggt aaaagctgga cgttatcagg aaaaagagaa ctggcaagaa attgcacgct
    11821 tattagaagt tcgtaaggga tacgaacaag aactcgaaga gttggaattt agccgaagga
    11881 aaggaaggct agaattcatt cgcttttatc gattttcatt gccaatacct gcgattttag
    11941 cggttaaaaa aggctgcgat aaaatgaaga tatatgaaaa ctgtgtggca gcacttagca
    12001 gcgaaaaacc tcttatggaa gaaatttcat tggtgactgt cacttgggaa atgagtcgcc
    12061 agccaacaga agaacagaca tatctttctt tagaagagat tgagatagaa ttagaggaaa
    12121 ttggtcgcta tgccacttgt tctacctatt gtggatcggt cattagtatt gctggtgtga
    12181 ttgtctaaat gaaaaaaatt atgatttatg ttggtgcgta ttggtcacgt gatccaacag
    12241 tattagaaaa tccagaggcg gtacactatt gcttgcgcca attattctat ctgtataaag
    12301 aacgattaga atcgttgatt cgtcagttac catatactga cagacgttta gatgaacttc
    12361 ttctaaggta tccagcaatg tataaacgac gaaaaaatag attgttacca gaagagtatc
    12421 ccattgaaaa acatgaactt gaagggcgat ttgtggctta tttctatgat gatgttcgta
    12481 tgcgcttagt agaacaacga atggaaatag aaaatgatcg ctactatttt atcaattatt
    12541 gtaagaagcg taagtatcaa gtaactgatg atttttatga ttgtatttta caagatgggg
    12601 aagtgattct atccaaaatt gctccaagtt ttcgtgaact tgtgccgatt gattttttga
    12661 aaaaatgtca tttgcggatt cttccgtaaa aaagagctat aaaaggaaag aaaagtagaa
    12721 gccaaatcgg tttctgcttt tttatttttt ttaggaagga gaagatggta tgtcactgga
    12781 atttttagga gagccaattg aaaaggaaga gttcgtttcg cattatatgg atttgtttat
    12841 tcaggtgata aaaaactttg tgcgattgat gaattttatc cacgcgaaca agactatcta
    12901 gccgctgaac gaataaaaat cagtttatta tgggaaaaat tcacagatga aaataaccga
    12961 ccgccagatt atcgctattt atcagattgt ttaacgaata atgtgctttc taaagaatac
    13021 ctatttcaca aacgtgagaa aaatcaaatg tcggttgaac atttttgtga ttgttatatt
    13081 gcattattgc gtagtcaaca gttattaaca gtagaacgat atggtgcaga gtttggttat
    13141 gtcatgcaag ctgagcgtca tagagctaca agatgctatg aaaaagaaga tcaagtgatt
    13201 gatggctatg aagaattatg tattcgaaac aatcgctatt tgcaacaacg tttatatgaa
    13261 caattgatga tggatttttc aaatctctat agagggtatg aatgttcgat gattcaagaa
    13321 aggtagaaga aaagggggaa tttttatgtg gcgattatta tttttggtgg tatgtggtat
    13381 ggcattgttc tatgtgtatc gtgtctatct ctatccacga atggaacgat ggacaagttg
    13441 gtatagagat cctttaaaac aacgaaaagg attgaagcgg tatcgttatg aattacttgt
    13501 tgaattttcg gatgggcgac aagcacagta ttattttttt gcaaactatc caaaatacaa
    13561 caccagtgaa ctattgattc aattattcaa aaataatcca tatgttgggt tagaagaaaa
    13621 cggacgggag ttcttttatc gttcagataa tattagtgcg gcgtctatga acaaaacacg
    13681 aattgcataa aaaattggag gaataatcat gaaaaaaaca acattagcag tcgtaacaac
    13741 actaggaatt tcattatttt cgtttcaatt agggagttca ttggtttatg cagatgaaac
    13801 tgtagaaaca cctaagtcag aaattgtaga aacattgcca ggggaaggat taccagatgt
    13861 tgagacagag ctaaatggag gaacaacgga aaaaccagca gaacctgaac aattgcagtc
    13921 agagaaacct gaaaaagagc cagtgacacc agaaccagag tttcctgaat caactttacc
    13981 gactgattcg atcgaagaag aaggtgtgca tagttcaaca acaacggatt caagtatagt
    14041 cacaactccg gaacaatcag gaacaaccag ttcttctgaa aagaatactg attcgtcaag
    14101 tacggaacag ccaacgatgt cgtctaccag tgaagaacaa aaagaagaac cgaaacaacc
    14161 tgttgaaaaa tcagaagcaa ttccaaaaga aaataaacct attgttccag caaaagaagt
    14221 cacagtatcg gtaaccccaa gcggtgaaat tacgacgaat acttctcaag gaatgagtgt
    14281 accgattgtc actagtaatg tagaggaatt gacccatatt ccaacaccaa ccaccccatt
    14341 aaaagtagca ggtgatcaaa caattgttgg tgtaaaagat ggtattccat taatccaaga
    14401 tagtgaaggg aatttggtaa aggatttgtc gattcctgta aagaaacttc caagtggcaa
    14461 tattgaaatc aaaacagcag atggaaaaac aaaagtctta ccaaagactg gtgaagaaat
    14521 acatgttgca ctttctgttc taggaggagt gttgacaagt attgctggat ttgttggata
    14581 taaaagaaag agaaaaggaa tagaaaatga gggtaattga atggactatt tttcagaaaa
    14641 acaagcttat cgttgtcaat cgtacgtact agtaaaaaca tactagaagg agtagcttat
    14701 gaaaaaacga caactacggc ggaaagaaaa agtttataca gagaaagtac cgaagcaaaa
    14761 gaaaatccat tcaaaaaaag cagtgaaatg gatttggtgt ttggttttat ttctttgttt
    14821 ttcagggggc ttggcatttt ttcaatccat gaaaacgaag gttcaagtgt cgtttttgaa
    14881 agatgaaatc caacaattac aaaagaaaga agtacaaagt cggtcagaat taacgtacac
    14941 acctgaaatt gaatccttta tgaatcgttt tgttgctttg tatatgaata cattcgataa
    15001 tcatgaacaa gaacaacaac gtcaagaaac attaaaaaaa gagttttatg cacaaaactt
    15061 tattcaagaa ccaggaagtg tttcaggtgt tcgaaaatta actgctgctt cgtttattgg
    15121 attaaaagaa attgaaacca ttccaactgc tagttataaa gtaacttatg atattcgctc
    15181 gatgaatcca gagagtaaga aagaaacaag tgtgacaatc acacaagtac tcaatcttcc
    15241 cttttctatt tcaaacaagg gctgtcgtat tattgcttat ccttatttta cggcactacc
    15301 aaagaataca gaaaaacaac gaatgattac ttatgatgac acattatacg aaacggttga
    15361 tgcgtcggaa gcgaaagatg ttgaaggatt tgtggaagat ttcttagata agtatgcgaa
    15421 aaa
//
LOCUS       DAFKHN010000056        15402 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFKHN010000056 DAFKHN010000000
VERSION     DAFKHN010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.056"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            147..533
                     /locus_tag="LY912_001926"
     CDS             147..533
                     /locus_tag="LY912_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBM6955596.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            627..818
                     /locus_tag="LY912_001927"
     CDS             627..818
                     /locus_tag="LY912_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955597.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            1332..1664
                     /locus_tag="LY912_001928"
     CDS             1332..1664
                     /locus_tag="LY912_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6955598.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            1960..2115
                     /locus_tag="LY912_001929"
     CDS             1960..2115
                     /locus_tag="LY912_001929"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBM6955599.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            2391..3731
                     /locus_tag="LY912_001930"
                     /pseudo
     CDS             2391..3731
                     /locus_tag="LY912_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(3972..5588)
                     /locus_tag="LY912_001931"
     CDS             complement(3972..5588)
                     /locus_tag="LY912_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBM6955600.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            5706..5924
                     /locus_tag="LY912_001932"
     CDS             5706..5924
                     /locus_tag="LY912_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955601.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            6119..6580
                     /locus_tag="LY912_001933"
     CDS             6119..6580
                     /locus_tag="LY912_001933"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBM6955602.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(6773..7012)
                     /locus_tag="LY912_001934"
     CDS             complement(6773..7012)
                     /locus_tag="LY912_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955603.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(7036..8559)
                     /locus_tag="LY912_001935"
     CDS             complement(7036..8559)
                     /locus_tag="LY912_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBM6955604.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(8577..8699)
                     /locus_tag="LY912_001936"
     CDS             complement(8577..8699)
                     /locus_tag="LY912_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBM6955605.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(8729..9712)
                     /locus_tag="LY912_001937"
     CDS             complement(8729..9712)
                     /locus_tag="LY912_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBM6955606.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(9736..9885)
                     /gene="rpmG"
                     /locus_tag="LY912_001938"
     CDS             complement(9736..9885)
                     /gene="rpmG"
                     /locus_tag="LY912_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBM6955607.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(9906..10283)
                     /locus_tag="LY912_001939"
     CDS             complement(9906..10283)
                     /locus_tag="LY912_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955608.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(10315..10494)
                     /gene="rpmF"
                     /locus_tag="LY912_001940"
     CDS             complement(10315..10494)
                     /gene="rpmF"
                     /locus_tag="LY912_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBM6955609.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(10509..10778)
                     /gene="rpsN"
                     /locus_tag="LY912_001941"
     CDS             complement(10509..10778)
                     /gene="rpsN"
                     /locus_tag="LY912_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBM6955610.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(11301..13067)
                     /locus_tag="LY912_001942"
     CDS             complement(11301..13067)
                     /locus_tag="LY912_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955611.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(13027..14781)
                     /locus_tag="LY912_001943"
     CDS             complement(13027..14781)
                     /locus_tag="LY912_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955612.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(14891..>15402)
                     /locus_tag="LY912_001944"
     CDS             complement(14891..>15402)
                     /locus_tag="LY912_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBM6955613.1"
                     /translation="FFSIMVSSIGGAFGHSISPGIFGLLSGIIFVYISYNYPRKGIFT
                     IYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVFGYDRAIPQVASWALMQLGSA
                     AGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGIWGIISVLVVASLSMIGVLIG
                     RKVLKKYKK"
BASE COUNT         4961 a         2960 c         2358 g         5123 t
ORIGIN      
        1 aaaacatttt tgaaaataaa catcagcagt cctatcaatg catgtgagct tatagaagtt
       61 attcgcagcg cagcataatt gcattagctt cttttcgtgt tttttgcctc ttttcccttt
      121 aaatcttaat ggaggaggtg tgcaatatgt cagataacga cgaacgcgta aatgcccagt
      181 tgattcgatt ctttgaaaag gtcattttga acaccgctaa tacttattat aaaaaacaag
      241 aagaaattca aaaacatgaa caacttgatc aactcccacc atatttgttt actaaagata
      301 ctataaaatt taaacaaccg attaatgttt taaatgtgac tctccttgtt gaagatataa
      361 aattagcaaa aatccttcct ttgttgaaag aacctgaaca aatttttctt atcgaaaaat
      421 ttatctttga taaaactgat aaagaaattg gaaaggttct ggggattaca agacagggtg
      481 cgacaaattt aaaacatcga ctttacaaaa aaattcaaaa aatgctggtt taatatctgc
      541 ataataacta attttgtatg cttctttgct cgttctcctc cttcccaaag aaatagatta
      601 taagtccatg ggaagaaggt agatttatga attctttaaa agaagatttc attttagcaa
      661 aggctggaaa tgaagaagct gttgaggcaa ttctcaaaag atttagctct ttgattcata
      721 agcaatcctg gagaactgga aaatatgatc aagattgtta tcaagaatgt atgcttgcaa
      781 tatatctagc tatctcgaaa ttcgaaatta aagaataact caactaaggg agtctgtgac
      841 ataagtaaaa agatagtttc aaatttcgaa caataaattt gaaactatct tctttataat
      901 tataaagtat cgattttaca gcgttctata atgattcata gaatctaaaa cgaatgattt
      961 taattatcaa cgttttttaa ttcgttttta gcttaaaaat aacttttgtc acagtctcac
     1021 tcctaaaatt actttattta cgtatgaagt gggcaggagg tcgaatccag aactgggcta
     1081 tggtacttca acgaggactt ctcctctaga attgaaaagc atgcgattta ccttccgtaa
     1141 cgacggtaga tttattcaac tatgtgtcca atcaaaattt gtctgatttc aaaaatagtc
     1201 aagagaattt tggttgttaa aaactcttat ctatcaactt ccacagttta gttgacaaac
     1261 cctgatacta agttgggcta tgatacactt ttcttgacta tcagttacgt taccggaagg
     1321 aatgaactct attgagaaaa acatatgatc gtaaatttaa actaaagatt tcacaggata
     1381 tccttgagaa aaaagtaact accaagaaaa ttgctgaaga atacaatatc tctcgtccaa
     1441 caatttcccg atgggtttca gaatatcgtc gatacgggaa aaatgctttt gctggacaag
     1501 gaaaaagatt acctgataaa gcagatttct acattcttga acaggaaaat aaacgactaa
     1561 aagaggaaga cgagtgttct acgaacacaa agatcgatac ggatctccag ggatcactca
     1621 aaaactttac gatgaaggaa tcgaaatcaa taaacgtgtt gtagctgttc ttatgcgtga
     1681 aatgaattta tgcacaagag gatttcatcg acgcaaatct tctcatggta gagaaaaaac
     1741 aatcaaagaa atggtaaaaa aatgttgaat cgataatttg aacagaacca aattgatgct
     1801 gtttgggtga tggatattac ttacattcca tgtaatgacg gtcgcctcta tttgtccacc
     1861 tatattgact tagcaactcg tattctacgt tactatatgg tagattcaca catgaaaaaa
     1921 gagattgtcg tccgtccatt acaaatttat taaggagaat tgcctacggt aattcattcc
     1981 gatagaggta gccagcatcg gtcttttatt tatcaagagc tgttgaacga ccaccacatc
     2041 acacattcag tgagccaaac tgggactcct gttgacaatg cagtaattga agcgtttcat
     2101 cgatcaatca aatgagaatt aatcgactcc aacaaatata aaagtaaaat agagatgaag
     2161 gtgttaatcc aagattattt agaagactac tacccaaaca aaagaatcca tacaaaattt
     2221 atgatgactc cttgacaatt tgaagcgaag aaaataaggg atctataata tctagtgttg
     2281 gtgacgcctt ctgttgccaa tactttttct tttttctaat aaacgcaaac agacacctta
     2341 aaatccttta gaataaagtc gacgaaaacc attcaaagga gtgtttcaag atgtcctatt
     2401 cagagtttac caaagagtta ctagatattc tagacctaaa tcttatcttt catgaagatg
     2461 cctttcgcaa agagcgaatc aatgacgaaa catgttttgt ttttgatggc acattgacct
     2521 atcaaccgga ggaatgcttt catcgccact atcaaaatga acaaacgatc attaaatagg
     2581 gctggaaaaa agtatccatc ttattgaatg atgtcagtaa ctacaagacc attctgcgga
     2641 ttaacaaaca gcgcttcaaa tgtaaacact gtggaaagac ttttttagca gaagattcag
     2701 ttagtgatcg tcgctgctcc attgctcgca gagtcaaaca agccattctt gagctattaa
     2761 gcgaacctct ttctatgtct ttgatcgcac gtatgaagca catttctccg accactgtca
     2821 ttcgaatact tcgcagcctt cggcctaaaa ccatttcttt gagccagctg ttaccagaag
     2881 tggtgtgttt cgatgaattc aaatcagtga aaaatgtctc gggagccatg agctttgtca
     2941 tgatggacgg caagacccat caactgattg atattgtgga aaatcggcaa ctcaatcctt
     3001 tacgcgacta tttcttgcgc taccctataa aagtccgtga acaagtgcgt ctagtggttt
     3061 cagatttcta tacaccctat cgcacattgg tgaaagagtg ttttccgaat gcccgaatcg
     3121 tcgccgatcg ctttcatatt agccaacaca ttggtcgggc ttttaccaac caccgaattc
     3181 aagtaatgaa gacctttaaa aaaggggatc gtcggtcgaa gcacttaaag aaatactgga
     3241 aactacttca aaagaatgcg tgggaattga aaggtcagca tcgctactgg cgtccgtcat
     3301 ttcgagatca tctgacagaa gcagagatag tcgatcggct attatcttat gatgattcct
     3361 taaagcgagg ctacgaagtc taccaggatt ttctttccgt tatcagaaga caagatgttc
     3421 ctgaattcgt cgcgctccta aaagaagact acaaggagtt gccagagcac taccaaccag
     3481 tgttcacgac cttcaagaaa taccaaacag aaatcaaacg agcgttgcgc gttccctatt
     3541 ccaacggccc tatagaatgt ttgaataacc atatcaaagt actaaaacga attgcctatg
     3601 gctatagaaa ctttcaaaac taccgagaac gaatcttttt atatcgagga aaatatttta
     3661 agaaaactaa gaatactacc caactgacta aagccagaac aacaacacgg ctagacaaga
     3721 tagctgtcta gccgtgtgag tatctcgatt attctattga atttcttcac caacactcat
     3781 tgacgaagag ccaaaataag taatctaacc gactgttaac taaaccattg caggtcccgt
     3841 taaagatact tgtgcctgtt gtcaccgctt ctttttcttg tccacaagcg cttaacacac
     3901 ttaataaagc ccctgctatt attaataata atatcttttt cttattaaaa acctcctcat
     3961 ctatttccag attagtaaat gtagtaatct gtgctttctt ttttctcaat actaataact
     4021 aacttatggg gtaaacaaat actcgtttga ccgggttttg agatccatcc agttctaacc
     4081 gcgatttgat caggactatt atcttcttta actcgaattc ttccatcttt aatctcaaca
     4141 atattatatt gtcccttcgc aggatgataa ttcacgagtt tatgattgat cttatccaaa
     4201 tcgaagcgat ccatttcctt gccatcaatt cgaacgatgg catatttgat agcatcttca
     4261 gttgtttcat tctccttttc tatagagaat acaaataagg gaataaaaga ggtaataatc
     4321 aaaatgccaa taattatgac atcgcctatc ttgacaccag cttttcttaa aaatttcatt
     4381 aacgatatct ggctaaacat attagacttt ttccatggaa atggtgaaat ttttcggaaa
     4441 ttatctgcat taagagaatc agttaaacaa ccctcaagtt gttccttaat acattgttga
     4501 tccatcttca taccaataaa aactagttta ttaatgcgtt caccaaacaa cggatgccag
     4561 gcttccttca attcgggatt tttttgtata atcatttgac actcaatttt aggtaaacta
     4621 gctacccaat aatttaatga ttcaatactt ttatagctac ccgatgtttc aaagatcgtc
     4681 gaaaaatcac tatgttgggc aaaccaaaga aacccttttg ctcttgtaat attgccagga
     4741 aaatttttat ccgtaagatg ggcaaatttt tgtgcgtcaa ggagtaaccg atttcgatag
     4801 ataaaacttg agataccata ttcttctgtt tcaggaatat gattttgata gccaagctct
     4861 aactctttga accagcccac tgaataggaa gtctcatcta tattaaaaag atttgtattt
     4921 agaattttcg ataagtctac ttcaccttta attgtcctaa ttattttggc attggactgt
     4981 aacttagcaa ttagaccgtt aattttgtaa atcgtcttgg ttgacactaa gtcactatta
     5041 tttaaaagta atatgttaca acactcgaat tgatcaatta acaagccacg aatatcctgt
     5101 tcttcttcaa ctacattacc ttcagctttt ctttcctgaa tcttttcacc cgtttcgaaa
     5161 ttatcccaaa aacgttttac atccactact ataataatgg caccaatctc taatcgttgg
     5221 gtcaaatcaa tgtctaaagg gtttttagct aatataattg cttgaataat tggaattggt
     5281 ttgctgattc ctgaagcttc aataacaatt tgattcaagt cagaaaattg cactaattga
     5341 tctagttcaa caatcaaatc ttcgcgtaat gtacaacaaa tgcatccatt cggcatcgaa
     5401 acaagttttt ctccagttct tttaaaacct ttcttgtcga ctaatacccc atcaacattt
     5461 acttccccta tgtcatttac aatgacagca atttcctttc cgtgatcacc gtacagaata
     5521 tgatttagaa gtatcgtttt tcctgaacca agatagccag ttaagattgt aataggtatt
     5581 tttttcatag ggaacctctt tctatacctt gaatttacac tttaagtgca acacataaaa
     5641 atgagtcata atcgatatcc aactagtata agtttgtcga gaacactcct agaaggaaaa
     5701 taattatgag ccagtatcgt catcttacta tactcgaacg agaaagaatc tttctgcttc
     5761 acgaagaagg attttctatt agtataattg gcaacgacat tcagcatagc ccgtttacta
     5821 ttttacatga actgagaaga aacaagaaaa aaactattca ccttccaaag cggaaaaaaa
     5881 ttatgcttat cgaagaaaaa aatgcggacg ttatcacatt ctaaatgatc cgtgagtttg
     5941 gtcaattgtt cgtcatttat ttgtcgattt tcagtggtcg ccagaggaaa tctcgaatcg
     6001 tttgaagcat gaacatatgg acttttcaat tagttttatc acgatctaac gtgcaatttg
     6061 caatgatctt ttcgatacag aacccctctc acacggcaat aaaggcctga tccgttcatt
     6121 gcaccatcga ggaaaaacaa gacatacaaa aaatcatgtc gagtctcgtg gaaagatttg
     6181 ccttactcat tcgatccatg gccgtccaaa atccgcagat gatagaagtg attttggtca
     6241 ttggaaagcc gatattgtag ctggcaaaac tggtggtact tgtttagtga ctttgacaga
     6301 cagaaaatca tgcttccttt tagcaggaaa gaaggtcccc agaaagaaag ccgcttatgt
     6361 gagcgagaaa atgattgaac ttttaagcag tattccaaat gaggcggtca aaacgatcac
     6421 tccagataga ggaaaagaat tctccaatca tttcgcagtt acagaagcat tgaataatat
     6481 gcccttttat tttccagatc ctcatgccct tggcaacaat gaacaaatta aaatacgaat
     6541 agactcattc gagaatactt gccaaaatcg aaagagatag ctacggtaga taactcaacg
     6601 ataaatcaga tgattgaaaa actgaataac agacctagaa agtgtttaga ttggagaaca
     6661 ccttatgaag tcttctttga taaagtgttg cgcttgattt gacaattcaa gacataataa
     6721 aaagcagatc aaatccaaat aagggaaaaa tgatctactc tggtattatc aattaattgg
     6781 ccaagctatt atgccgtttt gctaaacgtc tacttcttcc agtattgacc ttgataaaac
     6841 aacaatcagg atcccgtttt aatactctat gaactgtgtc aatactaaca tgtaaagttg
     6901 cagcaatatc agctaatgta ctcccattta atctcatttg ctttgcaaat cgataacgcc
     6961 gataagcatc aatattcttg gaatccatag acaataatac ttttcttacc atgtatttcc
     7021 tccaaaaatt gaattttaat gagccatcat ttcttgagca atttcatgtt tagacaatga
     7081 agctggatag aaagtaggcc aattatgcaa ttcattatag agtttttctt gactttctcc
     7141 accaaagaaa atatggaaat gctctgcctt acttggtgca attccatgat cactaaattg
     7201 aatatattta aaacgaccag cacctgcatc atcagtttca aaattaaaac gaacaccacg
     7261 gtttcctttt tcataattca aaattttgta tccaacatat ttgtatgtgt attgatgatg
     7321 ttcaccgttg actacaaaat caatggtgtt gtctttaatg ttgatagtat caatatctgt
     7381 cttatagcca gtagtataat aatctttgta ctcggcagct gtcatgtctt tattgatttt
     7441 tgctttgtaa tcgaaaactt catccaaaat tccatctttt aacaacggat aaacagattg
     7501 ccattcgcct gtataatcac tcaattcgcg atccttcaca tcggcatctt taaagtaccc
     7561 attagcaact gtcttttcat ccttcgcttc tttttctgga actacctctt caccagcaac
     7621 catagttgtt ttttctaacg cttttagatt gtcttccatt actgaaacat aatcttcacc
     7681 attatccatt tgttcttttg taagactttc aagaggattc agtacttcca attttatccc
     7741 agcttcgttg gccaaagttt ttgcaatttt atcattagca ttcttttcaa agtaaatata
     7801 attgatctta ttttttttaa catactcttt taattcagct aatcgaccag aagatggctc
     7861 ttcttcagga cttagtccag caataggaac ttgtttcaat ccataatcca aagctaaata
     7921 tccaaaggct gcgtgttgcg tcacaaaact tttttgtttc gcttctttaa gactagtggt
     7981 atagtcagca tccaaccgtt tcagtttagt caaatacttt tcagcatttg tctcaaatac
     8041 ttttgctttt ttcggataca atttaactaa ctgatccttg atatttgaaa cttccttaat
     8101 tgccattttg ggtgaaaccc acgtatgagg atctagttca tgatggtgat cttcttctcc
     8161 gtgatcatga tcttcttctt cactacctgg caataaaatc atgtcttttg ttccttctac
     8221 tacattaggc ccagctttct tccaactttc tttagctttt ggtacccatg attccatgtt
     8281 ttcgttatga tatacaaaaa catcagcatc atgagctttt gccatatcct tagctgaggg
     8341 ctcatagtca tgaggttctg atcccgctgg aaccattaaa tccacgttcg cttcatcgcc
     8401 gacgatgttt ttggtgaaat catacattgg atagaatgtt gttacaattt ctaattttcc
     8461 atctttatca ttcgatactt ttgcatcatt agtgctggag caagctccca ataatcctag
     8521 agctgctatc ccaataagtc ctacactgat tttcttcatt ctttttcctt ccttaattat
     8581 gctaatttct tcattttatt tcgtttatgt tctttgataa tttttaatgc cctttttcta
     8641 gttttaatat tcgggctttt aagtcgtcga tatgcactag atatatccgt tttctccatt
     8701 agaaattacc cccaatcact acttatcatt atttgctttc cgccagtaat ttatcaaaac
     8761 tctgtttgat cctttcttca tccaacattt ttccgattag aataatagtg gtttggtctt
     8821 tttgtcgagt ggtgtattga aaattaacct gttcgtttac ctcttgcatg gcaactataa
     8881 aatcctgctc ttgtaaagca atcaatcctt taaaacgata caggctccct tggttggtta
     8941 aaatcagcca gtcaatccat tggagtaaaa aatctttttt tatgtcttga tctgaagtta
     9001 agagaattga tttaaactca tgtacttgat ggtgttgatg atagtatttg ccattatagt
     9061 gattttctga tgaatcactt tcaaaaacta agggatgatt aaattttttc aaattataaa
     9121 aatccttttt ttgaatcgtt tcactatgtg tgaacattcg aatatcggat aaagggttaa
     9181 tacttttgat ttctctctgt aattttttta gtgcagataa attcaagttt tgttttctag
     9241 acacaaaaat gcgatctgcc atgacaagtt gcttaagggc ttgtggttct ctttcaataa
     9301 gttcaaaact gtcactatca ataacagtca ataaactatc gatatatact cttcctctta
     9361 gttgaggcgc tgttaaaagt gtttgaatga ttggttgggg atctgctata cctgtagttt
     9421 caatgatgat ttgtgaaatt ggttgttgat gttcttctat tgtttccagt aaagaaatca
     9481 atattgctaa taaatcactg cgaagactgc aacacataca tccattattt agttgtaaca
     9541 cccgttcctc gctatgaact aataatttgt gatcaatccc aacttcacca aactcatttt
     9601 caattataat aatttcttcc ctggggtagg gtgagacttg caaggcttga ttgattagcg
     9661 ttgtttttcc agcccctaaa aacccagaaa cgattgtaac tggtatgccc attttgtcac
     9721 ctttttacca cttagctatt tcacttcttt aaaaattgcc cgtctgcgca attttggcga
     9781 atactttttt aattctaacc gttcagggtt attccgttta tttttgctgg tgagatacag
     9841 acgttctcca gtttcgacac attccaaaat aatattttga cgcataaatc ttcctccttc
     9901 aatacttatc gatcttcaag atatgcttga atttgttgtg catcttcaaa agttaactcg
     9961 ccagattcca attgtgaaac taaattttct ttcatatcaa caggtatctc ccaataacca
    10021 tcgatacatt gaaataactc ctcgtcatac tcttcaaaaa ttggatagat tcttaaaaaa
    10081 tcatcaaatg ataagccttg gtcctcatag taatctttga ctaatccatt ttcaattgcc
    10141 tgttgggtcg gtaaacccgt ttcagtaata attcctctct ctaccatcga acgataaaaa
    10201 gtgcatttat ctagcgattg ctgggtcgtt tcaagataat actttaatcc ttcttcaact
    10261 aaaggtgggt aaataatttc cattttgatt ccctcctaaa agttatatat taaactattt
    10321 tgaagctcct ttaattactt tctttccatt atagtaccct tttaaagata catgatggct
    10381 acgtctataa tcaccattcg cttcgtcaaa tgaaatttct ggttttacta cagtttgatg
    10441 agttcttctt aaccgtttct tcgccttaga tgtttttctt gctggtactg ccatgatatt
    10501 tcctcctttt accaacttgc tttttttact ccaggaatca acccttgatg ggcaagttct
    10561 ctaaacttaa tacgggacat accgaacttt cgcatatacc ctcttggacg accatccgtc
    10621 tgatcacgaa gcctcagacg attcggattt gaatctcttg gcaatttagc gagagcggtg
    10681 cgatctcctg cggcttttaa ttcctgacgt ttatctgcat acttttcaat catcgccatt
    10741 tgtttctttg ctttagcaat tttcgacttt tttgccatat acctttatac tccttttatt
    10801 ttgatttaga cacctcaaat cgtaatcgtt acgttttgac actgatactt taccaacaag
    10861 agttgctctt gtcaacaata aataacatga aataaaactc atatgaatag ataactattt
    10921 gaaaacgaat ttatcggtac atagagataa tcaaatcatt taaaagaata tgcagtttag
    10981 gctctgaaaa ataagaattc acttttatta gtccaatcaa acacaaatac cgttttaagt
    11041 agcttttcct ctacttaaaa cggcaatatg aaagaaacta taacttttta ttcaatcttt
    11101 tatgtttaac tggtttatcg ccaatttttt aaaactttga ttattcctta tattataaga
    11161 atagacatta agtgaactaa ttcaatcata ctgattcttt cgtgtattca aaattagatg
    11221 ctgtttaata aaattattct ttttgaaaaa gaattataac tatatcccaa aaattgtagg
    11281 ttaatttaaa gcctatttca tcatcgtgat tgagcttctt tttcatagac gaatttctca
    11341 gatagtttag ttttctttat gagatttttg tatatttctg accttcgata caactcatta
    11401 tgagtacctt gatcaactag ttttccttga tccatcacta caattttatt taccttttca
    11461 atagacttca agcgatgcga tataattagt actgtcttat cttgtattaa acgatttaaa
    11521 ctttcctgaa tacgtttttc attttccgca tctaaactgg cagtaatttc atctaaaatt
    11581 aaaattggcg catttttcaa aaaagcccgt gctatggata ggcgttgtcg ctctcctcca
    11641 gaaagtgaac ttccgttttc tccgaccaat gtatgataac cgtcaggtag tttttcaata
    11701 aagtcttcgc agttagctaa acgagctgct tttttcactt cctcatctga cgcttgacta
    11761 tttccaatac gtatattttc caaaatactt gtattaaaca aagttacctc ttgaaaaaca
    11821 atagcgattt tgctaaacaa agaagctgga gatacacgtt taatatcata cccatcaatt
    11881 aaaatacagc cttcatcata atcatacagt ctagacacta atttcaagat actagttttc
    11941 ccggaaccac tagcacctac taacgcagtc acttctcctt gtttagccgt aaaagagata
    12001 tgatctaaaa ttggggtatt gttatcatat gagaaagaga catctcgcaa ctcaatgtca
    12061 aaagatttca gaggactatc tgatccctct tggatactgg tttccttcat agctctaatt
    12121 cgctgtattt taggagctaa ataaaatatt tcaagcactg cttctttcat agaatcgaag
    12181 gaatccttta tttttattgc ggctagtaag taaccaacga cgtagagtat agtcacttca
    12241 cccgttaaca gtaagtgaac acctactaga atgactactg ctaaactaac atatgagaaa
    12301 atagaggata aggccatgac tgaaaaagta cttaattcta cctttaaatg aatcctttca
    12361 ctctcttcca tttttttgaa aagtctgtct tgaacttttt tagatagatt aaagctatta
    12421 atctcttgct gcaattctat agtttcttga aattcttccg agttttctct caaagtatcg
    12481 taatatttag tattggcttt cgtttgggat ttctttgata acaagattaa gacaaaacta
    12541 aataacgttg gcaaaataac agctaatccc attttgacat taccaaccaa aagcatcact
    12601 gaaataaaag ggaaaaacag agccataccg ccggctttag gtattgcatg actcatcgca
    12661 tgctcaatac cttcaacgtc agacatgata gtttgagata aatctgataa attatgtttt
    12721 gaaaaatagg ataatggtaa atttgacaaa tcgtctgcaa tttgcactct taaatgcgca
    12781 ctttctttat aagtactatt atataagttt tcatactccc tatctaacaa ccaatacatg
    12841 aaaagcaaag taacaaacga tacggcaaaa taaagccaac ggggctttgt attttctaaa
    12901 actaattcgt ctatcagcat cattataatg aatgctggta ccatattaat gcagtataca
    12961 aaaaaactag aaatagaagc tttagttaaa gcttctgcgc cctgatcact taaagcaaat
    13021 ttgtttttat aaaaactttt cattgtcaag cctccaatca tttgcattct cataattagt
    13081 gaccaattgt ttatacactt gatgtttagc cattaattca ttatgatttc cacgttctac
    13141 tattttccct tctgacaaga caagaatttc atctacagat ttaatgctgg ataatcgatg
    13201 agctatcata ataactgttt tttcttttat cagatgttga aaagcctttt gtagttcata
    13261 ctcattatct ggatcaatag atgcactggc ttcatccata ataacaatct ttgcatcttt
    13321 taaaattgct ctggcaatag ctatacgttg tttttctcct cctgacagat aaactccttt
    13381 actaccaatt aaggtatgct ctctttcggg aaatttttct aaaatcgatt cgcaaccggc
    13441 taatcttagc gcgtcaaata ctttacttgc tggcgcttga ggatttgcta tagaaacgtt
    13501 atcgtaaata ctctgattga atagtttcgt atcttgaaag acaaaagcaa ttgtgttaat
    13561 aattgtgtct tttgaatagt gatttaaagg cttaccacca attttaatct gtcccttatc
    13621 cacattgtag aaacctgaaa ttagtttagc tatcgtactc tttccgcttc ctgattttcc
    13681 tactaatgca taaattcttt tttgttctaa aactaagttg aaattttcta aaacacactc
    13741 ttctttgtat gaaaagctga cattttcaaa tgcaatgtca caatttttaa tctgtgtctc
    13801 gttcccatat tttagttggt cttgcttcat ttctaaataa agggagtcta gtgtttcgac
    13861 tgcatatctt gcttcaaaca agtgcatact tacatacatt attctcatga aagaaacaaa
    13921 aataattcca cttaaaaaaa acaacatcaa caagtcaaca gctaatatct tgggagtggt
    13981 aagagaagtt ataaaaaagg ttataggaac tatcaaaatg caaactatgc caaaaaatag
    14041 ccattgaaaa agaacaaaag gtgttttccc actcaaagaa tacttatatg caaacttagc
    14101 ataatcgtta attgctttat tcaaggcttt aaatgatgtt actttagcac caaatatctt
    14161 tataacttga attccgcgga tatattctac cgtttcagag cttaacacat ctaacgattc
    14221 ttgatatttt tgaataaaat ttgtattctc tgtcattttc tttaacaaga atacaccaat
    14281 tactaacatg gcgattagaa ccaatccaat tttaaagtta atgaaaaagc ctaaggcaac
    14341 tgataaaaca ggtgttacta tggcttgagc actatctgga atcaagtgag caattgccat
    14401 atgtgtttta gccgcgttgt catcaattgt ctttcgaata tatcccgaag aatttaaatc
    14461 aaaaaaacga aaacttgctt ctgttaaacc gctaattccc ttttttctca aattagtctc
    14521 taagcgaaac ccaaggatat gagaaaataa gccagaaaaa atataaaata aagctcctaa
    14581 agttaaccaa gcaacagttt gaaccgcata actcttagct aaatattcat ctcctacaat
    14641 aattagagac tgaagaaatt tgtaaatact gtaatatcca tagactgtta atacgacaga
    14701 aaaatcagaa aataaagtgg ctaaccatcc gtagtatttc attttaggga cataactaaa
    14761 taattttttg tatactttca ttttttcctc ccccgcattc aatttcttct cttattcgtt
    14821 tacaactgtt aatgctttcc gtaatagcgt aaattagaga tgtacaaaca gataaaaggt
    14881 aaactacgtt ctattttttg tattttttta agacttttct tccaatcaat acaccaatca
    14941 tagataaact tgctacaact aacactgaaa tgattcccca tatacctacc gcatagtgga
    15001 tcattgcatc cattgttgca gcagattgtc ctttatctat ccaatcttga cgaaaacgat
    15061 ctgtaaagaa ccatatagga atccactgtc cggcagcact gcctaattgc attagagccc
    15121 aagacgcaac ttgaggaatt gctcgatcat atccaaatac agatagaata atatcagcta
    15181 agatcgccat actaatcgaa ctgataaacc aaggtaagta cgccccgccc attaacgtaa
    15241 aaaataacaa taaaacaatt gtgtaaatag taaaaattcc ttttctaggg tagttatagc
    15301 taatataaac aaatatgatt ccagataata atccaaaaat cccgggggat atgctgtgac
    15361 caaacgcccc accaatacta ctaaccatta ttgaaaaaaa gt
//
LOCUS       DAFKHN010000057        14850 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFKHN010000057 DAFKHN010000000
VERSION     DAFKHN010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.057"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            57..818
                     /locus_tag="LY912_001945"
     CDS             57..818
                     /locus_tag="LY912_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBM6955614.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            1046..1240
                     /locus_tag="LY912_001946"
     CDS             1046..1240
                     /locus_tag="LY912_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955615.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            1509..1808
                     /locus_tag="LY912_001947"
     CDS             1509..1808
                     /locus_tag="LY912_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955616.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1905..2339)
                     /locus_tag="LY912_001948"
     CDS             complement(1905..2339)
                     /locus_tag="LY912_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6955617.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(2571..3281)
                     /locus_tag="LY912_001949"
     CDS             complement(2571..3281)
                     /locus_tag="LY912_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBM6955618.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(3271..4131)
                     /locus_tag="LY912_001950"
     CDS             complement(3271..4131)
                     /locus_tag="LY912_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBM6955619.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(4136..4774)
                     /locus_tag="LY912_001951"
     CDS             complement(4136..4774)
                     /locus_tag="LY912_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBM6955620.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(4789..5088)
                     /locus_tag="LY912_001952"
     CDS             complement(4789..5088)
                     /locus_tag="LY912_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6955621.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(5131..6615)
                     /locus_tag="LY912_001953"
     CDS             complement(5131..6615)
                     /locus_tag="LY912_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBM6955622.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(6635..7096)
                     /locus_tag="LY912_001954"
     CDS             complement(6635..7096)
                     /locus_tag="LY912_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6955623.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(7114..8181)
                     /gene="ulaG"
                     /locus_tag="LY912_001955"
     CDS             complement(7114..8181)
                     /gene="ulaG"
                     /locus_tag="LY912_001955"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBM6955624.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            8399..9169
                     /locus_tag="LY912_001956"
     CDS             8399..9169
                     /locus_tag="LY912_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBM6955625.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(9442..10270)
                     /locus_tag="LY912_001957"
                     /pseudo
     CDS             complement(9442..10270)
                     /locus_tag="LY912_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            10837..12072
                     /locus_tag="LY912_001958"
     CDS             10837..12072
                     /locus_tag="LY912_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBM6955626.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(13071..13331)
                     /locus_tag="LY912_001959"
     CDS             complement(13071..13331)
                     /locus_tag="LY912_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBM6955627.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(13358..14659)
                     /locus_tag="LY912_001960"
     CDS             complement(13358..14659)
                     /locus_tag="LY912_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6955628.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
BASE COUNT         4740 a         2994 c         2371 g         4745 t
ORIGIN      
        1 ttttcactat attttatcac atgaaaattc attaagaaag taggaatcga agtattatgc
       61 acacaccaga agaaattatg gaactcagta ttcatcttgg aacaaaaaaa atacataaac
      121 ctatcttagc taaactgatt ttaggtttta tcggaggagc catgatttct ctaggttatt
      181 tggcatacgt acgagtctct gcttctatcc cagaatctat ggctagcttg actagtttag
      241 ttggtgcctc ggtttttcct atcggcctgc tggtcatcct tcttggcggt ggtgaattga
      301 tcaccggaaa tatgatggct gtggcgattg cctttatgga taaaaaagtc acattctcac
      361 agctggttaa gaattggtca gtgattactt ttgcaaatat tattggtgca attttcgttg
      421 cctatttctt tggacacttt gttggtttaa ctcattcagg tgtctatctc gaccaagtga
      481 ttcatattgc tgatcataaa atcgctgttt cttggtggca agcattaggc tccggaatag
      541 gttgtaattg gtttgtcggt ttagcgttat ggttatcata tggagcaaaa gatgcggccg
      601 gcaaagtact aacgatttgg tttccagtca tgatttttgt ggcaatcggt ttccagcata
      661 gtgtggccaa ctgttttgtg atacctgctg ccatatttga aggtcaagcg acttggttag
      721 aatttctctc gaattttatc cccgtttata ttggaaatat catcggcgga gctatttttg
      781 tttcaggttt ttattacgtt agttataagc atcattaaga ttgaaggtaa tgttcattcg
      841 agcattacct tcaatctctt tatatactat ttatatttta agaacaatag ccttttatta
      901 tatatattat tcaaattagt tatatcgagt gaaaaaaact ttcaaattga ttctttttat
      961 ttatcataaa gatatagata cataatcatt ttcacttaca tatatttgaa tattaactaa
     1021 aaacagcaag aaagaagagg atcaaatgta ttatgtagaa gtaaaaacaa aaggcgtcaa
     1081 aaacaaacaa tatgtgaaag gtatcagtaa cgaatatcct ttacttggtt catggaaaga
     1141 agctgctcct ttttccaaac catgtgccat aaaaataaag aacgagctag aaaaagaact
     1201 gacttgtggc aaagctgttg tagatatcat cgaaaagtaa atccaatgta tagaaaggaa
     1261 gatcacacat gaaaagcgac gtacaaattg ctaagattat agaattagaa gaagaagacg
     1321 cagtgttgac aattgaaaaa aaataaatgt ttgtatacca tatgattatt tcaatatgta
     1381 tcctggaatt ggagatctcg tagagctata tcaagatgaa tcaaatatac ttgtcattca
     1441 tcatgaaata tagagactta taaaattgtt tatttttata atgtatcagt atagaaagga
     1501 aataaaacat ggattatact gttgaatttg acagtgaact acttaagcaa tttccacaag
     1561 aagaacattt catgtataaa gaagcaattt cccacaaagt gacagagtat ttggagcata
     1621 atttttttcg tataaagcca gtgcgtactc gttcggcaaa aggaatatac gagatgaaag
     1681 tcaaaattaa taaaaaaaat tatcgcatag catttgcttt aaaaaaaaat catgtgttca
     1741 ttttttatat tagttcgaat ttgcaaaaaa ttgtatttga taaagaggtg agtaaaaaaa
     1801 taaaatagct gagcattgga ggatagattg agtgatacta agtctatcct cttgtttttc
     1861 taaagaacta agctagaatt ttttcttttg tacgttatta tatgttattt gtcattacca
     1921 aaaagcacct tttttcttct agtatctatg acataagaaa taccacccat ttcctttact
     1981 tgaacaaatc ctactgattc ataaaatttt tttgttttct cagtatcatc tgtcaataat
     2041 tcgatttgga ctggtccata actagtgatc ttctccaaag cttcattcaa aagcactttg
     2101 cctattcctt ggcgctgata cctcggatga atgaggatat cttgaataaa tgcgatcgtc
     2161 gcaaaatcag tgatccaacg aacgattccg ataatcttcc cttccccatt acgctttatc
     2221 agagattcag attgttcaaa tgctctagct aaccttgcag tgtcttttgt gtaattcgtc
     2281 caaccaacgc tcttatataa ttcagaaatc tcatcgatca taagggaatc aatattcatt
     2341 tttttcttcc tttcttatac aattctccct ctaataatac agttctttga ctatttaatc
     2401 tatcacatat aactctcctg taaagattct ctcgattcct taaaatctct ctttcctttt
     2461 agaatgcatc ctttttgata aataaaaagg ttgtgataaa ttttcttcac aacctctgtt
     2521 tctctctatc aagtgttatc ttttaatttt ctacccttac cctagcatct ctattgcccg
     2581 tagtatgcat actttccatg tttgcgaaaa taatgtttat ctagtaaata ttgcgggatt
     2641 tcacatatat tggggttgat cagctcgttt tctttggcca tcagacaaat ttcatctaag
     2701 atcaaactgt tttctactgc tttcataggt gaatcccccc atgtgaacgg tccatgtcca
     2761 tagacaagta ctccagggac ttcgtttgga tctaattttc tttccttaaa cgtctcgaca
     2821 atcacattcc ctgtatgaac ttcgtaagct tctcttactt cttctttcgt taattggcgt
     2881 gtacaaggaa ccttaccata aaaagcatca gcatgagtcg tgccataagc tggcaaatcg
     2941 cgtcctgctt gcgcccacat gacggagtgc gtggaatgag tatgagtaat agcagttata
     3001 tcttcaaaag tttgatacaa aacaacatgt gtggggagat ctgaagatgg ttttaagcta
     3061 tcttcttcta ttatatttcc cgacaaatct gttaccacca tttgatctgc ttgcatgcat
     3121 tcatatctga caccgcttgg cttaatgacg atgactccta gctcacggtc cacttcactc
     3181 acattgcccc aagtcaattt gactaatccg tatcgcggca atgccagatt tgcttcaagg
     3241 acacgttgct tcattgctgc aattttttct tcacaagaca tcatagccag cctccttcaa
     3301 tttagaactt aagtagtctt ttgcctgctg gatttctctt cgaaagtctt ggcttttttc
     3361 actccacatt tcaatcagaa atgttccatc ataatctaga cgtttcaaat gtcttaataa
     3421 tccaagaaaa tcaacacaac cgctaccaaa aggaacatca cgaaactggc ctgaatattc
     3481 ttttgttaca gggtaagtat cttttaagtg gatagcagtg atataatcga tccctttctc
     3541 aagttctcga gccggattat tttccggcca tgcggacaaa ttgcctaggt ctggatatac
     3601 ttgtagaaaa ggggaatgaa tctgttcttt gatttctaaa aattttgaaa tggagttcat
     3661 aaatggatca tccatgattt ccacggaaag aatgatgcca tatttagaag cttcctttac
     3721 gctttctttt attccttcga taaagtcttc tctggaattc attgatttct cttcataata
     3781 aacatcgtat ccagctattt ggattacttt gacgcttaga ttatgcgcca aatggattgc
     3841 ttttttcatt agttgtttcg ctgctttttt cttttctgga tcagcagaac caaacggaaa
     3901 tcgccgatgc gcacttaaac aaatcgaatg gatacgtaca ccggagctga acatctcttc
     3961 tctcagctca gctatctttt cttcagacca atctaatcgt gctaaccgct catccgtctc
     4021 atcaatcgac atctcgataa aatcgaagtc catttctttt acaagggaaa aacgttcttt
     4081 ccatgaaata tctttgggta atgctttttc ataaatccca atttgagcca tttccttacc
     4141 cccagatacg aatgatctca tctttgaagt tttgtgcggc cttcatcgga tcatttgctg
     4201 ctgtaatacc acgaccagtg ataaaggtat acacatcgat cccttcaaat aagtgtaatg
     4261 tgtgtggatt taatccacca gttacagaaa cattaaagcc tagttcaatc agttttttga
     4321 tcttcgataa atctttttca ccccaagttt caccagataa cagcgcatca cggctttgat
     4381 ggtagattac ctgccggata ccgatgttat gccaatccat ggcttgttca aaagtccaat
     4441 tgccgtagag ttctacttgc aattcaccta tttctttttg tgctgcctcc atagttggaa
     4501 tcgttgcaca acaaatgact gtcatccagt ctgctcctgc ttttgcaaca ttactcgcca
     4561 ctgttcctcc agcgtctgca catttcgtat cagcgactag ttttttatct gggaacatac
     4621 tgcgaataca gcgaatcgct ttttgtcctt cctgtaagca aagaattgtg cccacttcaa
     4681 taatatctac tacatcacca actttcataa catctcctaa tgcatgttct aagtcattgt
     4741 gatctaacgc aatttgcaaa ttcggcctgc tcatcttagt tccttccttt acttgttttt
     4801 ttggtaccac tttgtttcag caaatttttc actgatttct ttggctgaca tcacattttt
     4861 gataccgata actgtaactt cttttttctc tgcctgagta aacatattca aaaaattgac
     4921 tggcgtaaaa actacatcgt attggccagc tgaacttttt ccctctgaaa tggcacaatg
     4981 atggattttg gtaattggta cgtttagttc tttcattgct ttttccacac ttctcatcat
     5041 catcaagctt gttcctgatc catttgcaca cgatactaaa attctcatct taatccctcc
     5101 attatgagtg ttgtctaatc agattttctt ttatactctc tgcttttctg catatgtgtc
     5161 atagtcttct acaatcaaaa aataaccctc aggatttttc cgatattgta actgcggaat
     5221 agccaataaa ccaatgacaa ctacggcaat tccagcataa cctaggactt tcatgattac
     5281 tgtaaacaat ggccaagctg ttgcccagtc gaacatcccg atataaccac catatgttga
     5341 catcccaatc catgtagcga ataatgctga accgcctact tgtatgattc ctgaaagaaa
     5401 cgggaacagg caagcggctt tgaatccacc tcggttattg gcataaactg ctataacggc
     5461 attatcaaag aacaacggaa tgaaaccggc tatgacgatc gttggtgatt tcaataaaat
     5521 cagtaaacca atcatcaaaa actgtcccaa agcaccaaac aagaacccaa tcgttaccgc
     5581 atttggcgaa ccaaagccaa aagtagcagc tacgtcaatt cctggaacag ctcctggtaa
     5641 aattgtgttt gagattcctt ggaaagattg agttagttca tcgacgaatg tccgaacacc
     5701 taattgcaag atcgccagat ataccgcaaa atttaaagaa gtcgtcataa tgtagaataa
     5761 gaaactctgt ccttcttgca tgaattgcgc ttgaatcaaa taatctttgc ctagtacaat
     5821 cagaatgatc ccaaagaaaa atagcatgag taacgaagta gcaaccatat tctcattgaa
     5881 aatcgacaag aatcctggta atttgatatc ttcgattttt ttgtcttgct tgattgatct
     5941 atttttcttt tcatcccgct ttttcatcca ctcagctaat tttgcaaata taaagattcc
     6001 gaacatttgc tgatgtgcca ctgcaaatcc ggcaccttct gtcaattcct gcgtgattcc
     6061 tactgttaag ttagaagcta ctgcccaata acaacctaaa atcagtccca taaaaatcaa
     6121 tacttgtatc ctacctagat caggaaagca aaacagtaaa atccaaaaag cggtagctgc
     6181 ttgttgaacc tgaacgtttc cggtagtgaa aacggaacgc agtttcgtat atttctgaaa
     6241 acggactaat aagatattta aaacaaatgc aatcagtaat aaaatcatca catctccaaa
     6301 ggtacggcca aatgtctcca ttaatccagc atccacagca ttttgtccaa aataaggatc
     6361 tgtaaccatg gcatccaaat tgaaccgttc ctttagtcca accaaaatcg gccgaaaatt
     6421 attgaccaaa ccaccagagc caacagtcaa aataaagtaa ccgaccgttg cctttaagaa
     6481 tccagcgatg cattcatgaa gcgggcgttt cagcaaaata tagcctaata acacgataaa
     6541 accaatcagg tatgctggct gcgtcaagat atttgttgca aaatacgtcc aaatgcttaa
     6601 caaaaattcc cccatctttt ttctcctcta tcaattaatt atattctgcc atcacaactt
     6661 ggtaatcatc gatggagttc gtagagatga gacgctcaac caatccatct gtcattaata
     6721 attcggataa tttttggata ttttctagat gttcttctgg atcttttgct gcaagtgtaa
     6781 aaaacaaact agccgttttc tcctcatcct ccccttcact ttcaaaacgg attggctgtt
     6841 tcaacttggt aaatgaaata gctgttccaa aaacaccatc acttttttct gaagaatgcg
     6901 gcattgctac ttgaggtgcg atcacaatat aaggaccgta tttttctaca caatggatga
     6961 tctcctccac atacgtttca tcaataattt ccttatcgat caatacaaga cagctttcgg
     7021 cgatagcttc acgccaatcc gtgatttctt tatctgggta atgaatcaat tgatggtcaa
     7081 aaaagtattt cagcaagaaa ctccccttct ttcttataaa aacgacggaa acggtgtatc
     7141 attttcaatc gagaagacat cttcaaatcc tcgataaaaa ttaaactcaa gatcatcttt
     7201 gtttgtcgga tagatgaatt tcccgcctac ttgccagata taaggtttaa atccatactt
     7261 caggcgatcc tttttgaatt tccaaatttc agtgatctct tttgaatcag ccataaaatt
     7321 agaccaaata tcgtagtgga caggaatcac tacttttgca ttcaatgact ccgccatgcg
     7381 cagcatatca acagaagtaa ctttgtctgt tatccctcgt gggttttcac cataggcccc
     7441 taaacagaca tcgattttgt gttcattacc atgtttggca aataaattgg agtaatgtga
     7501 atctcctgca tgataaagat tccctcctga tgtttcgaat aaatagttta ctgcaatttg
     7561 atccatctcc tgaggcattt ttccttttaa tacctcttct ggatcttcac aagtgaccaa
     7621 cgctgtccga tcaaacgctt ctaaagctac tacattgatg tctttgattt tgactgcatc
     7681 acctggcttt actgtaatcg ttttttcttc aggaattccc catttttgcc acgtgcgaac
     7741 cacttctttt ggcccaatga atgttgcttc aggacaattt tgatgaactg ctgcggctgt
     7801 atggatatct agatgatcgg aatggatatg tgtaacgatt aaagcgtcta cattttttat
     7861 cgcaaaagga tcgattacga aaggctgagt acgtaaatta ggctgcatat tttgaacgcc
     7921 actcatacgc atcatctgat ggcctttttt catcatgcca ttcccatgac tacgttttcc
     7981 cgtcccacac catagatcac ataaaatatt cgttccttca tgacttttca gccaaattcc
     8041 cgtacagccc agccaccaca tagcaaaagt tccaggatcc actacttctg tttcgatttc
     8101 ttcattcaag tatgtgcccc actcaggaaa tgtttctact aaccactttt cttttgttac
     8161 ttcattgaca gttttactca tttgcttgct ccccccatat cgttgttcca acttacaagt
     8221 aaatattaat gtgtatcagc atccatggaa acccttttat atgaccgttt gttttttata
     8281 tgattttctt tcagtaatca atgattgttt cagtataata aagacagata tgaatgttta
     8341 aatgaacaac tagtcaaata aatccatgga tcaagatgtc cctcaggagg caaaagtcat
     8401 gaaaaactca cttgtcaata ttgaaaaacg tcaaaaagaa attttggaac tgcttcagca
     8461 gactgaacaa ctatcaactt tcgaattagc tgaatccctt gatgtatcta ttagtacgat
     8521 acgaagagat ttaaatttat tagaagaaaa aaacgagatc atacgcaatt acggttattg
     8581 ttcttataat tacaaaaacc agactgattt tgatcaatct ggtcctgaaa ggattaaaca
     8641 agcgattgcc agagaagcta gtaaatacat taacgattat gatacgctgt ttatcaattc
     8701 tagctcgact gcgttgaaaa cactggattt tcttcaatct aaccatttga cagtcattac
     8761 aaacaacgtg aaaatcaatt actctccgca caaagataat tgtagttata ttttaactgg
     8821 tggagagatg cgctttccaa aagaagcact agtgggcgac atcgcattaa atacgatttc
     8881 ttcagtcaat gcagacattt gtatcattgg ctgtagcgga gtcgatgtag tacatggggt
     8941 cacaacaaag atattaaatg aatcaacgat caacgaaatg atggtcaaca agacaatcaa
     9001 atgtaagatt ttagtcgctg atcatcgaaa aatcggactg acatcaaagt tcaagattgc
     9061 tgatatttca gtctttgatt atttgatcac tgataaattt tgttctgaaa aagtattaga
     9121 ggagatcaga aatacgggga taaaaaccat tcaagtagat tcattttaag aaccaggacg
     9181 taaatatgta aataggatta tcaaaaaaat gaataacaaa tttatcgata aatgaaaaac
     9241 acgctacgct caaattgata aaggaatccc aagatgtgtc catccaatcg ataccatcat
     9301 aatctattgc ttcttttata accgttatat gttgcctaaa taggaatcaa acaatatcga
     9361 aaaaaggagg tatgacaaaa gtcacacctc cttttttcga ataaacggta ttcaaatcag
     9421 aacactgatt tcacaaccac tttatttcag gtcgttttca atcaccttta ccgcgtaatc
     9481 atttccgttg aaacgcgcta ttttttttgc gtccatatat ctttctaaat aatcatcttc
     9541 tcctaattgc ttatggcaag aagcaatttc ataaagcaag tattccaatg cataagtcga
     9601 tttatgtttc ttattatact caataccctt ctcacataat tggattgctt tatcataatc
     9661 ctcgatttta cggtaatagg tggcgatatc ataatataca atgcagacca tcagattatc
     9721 aaaatcagtc tcactcaata ttttaagtgt acgctccaca taaactttcg caaaatctaa
     9781 ttctcctttt gacaagtaga tcattgccac gtttgcagct gcttgtaagt gatggatatc
     9841 tgtttcggtc gtttgttcca acacttgatt aaaataaaat aatgctgcat ctggtttttt
     9901 tcgcataaag atgatcaagc agtccttgat aaaataaaat ttgatttaaa agatcagaat
     9961 tacttacttt ttcctgatcg atcgtttgta aaattttata agattcttgg tattttgata
    10021 cagaattcaa tgattgaatc tcatttattt ttttcctgat tttgtcttct tctgtttcta
    10081 ctaatatatc ggagatctcg acattcagct ttttgcaaag cgcacttaag atattgatgc
    10141 ctggcgacat attcttgttt tcgatattgc tgacagttgc ttgttcacaa atgccttctg
    10201 ctaattgtac ttgtgttaac ccctttttct ttcggtattc ttttagtaat gctccatcta
    10261 ctttaatcaa aacaatttcc ttccctttaa aaaattattt ctcctttata tcatacacaa
    10321 aaaaaagttc taaacaacca aaaatgttta gaacagaata aaaattttaa ttttaaaata
    10381 atattcaaat taaacaactg gcgtatctgc tccttgattt ctttttgtgt tatctgaata
    10441 attatcgttt acagttataa cacatagtga aaattgtcat ggcgagaaag tctaagaata
    10501 tttttaaaca taactatttc tttcttacgt gtgtataatg acgacagcac acctatcaat
    10561 taatataatt attttatttt ttatgttctc atgtttattt ttaatgacac aacttctcgt
    10621 atttatctgg cacaacatat aaatcgatca aaaaattgtt gcgtgttttt ttgaaaattg
    10681 gagtttcaac ttgattacaa aatttaaatt tagaagttgt gaaaacagcg agagacagtt
    10741 taatattcaa aatatacata ggctactcga acgctgtgtt ttttagtata ctagtaagaa
    10801 acgaagggat agactcattc caataaggag gatttcatga agacaattct ttttgctcct
    10861 gcagtattca atttagctga gacaacacga atgattgagg ttgccaaagc tatgaaagac
    10921 cgttattact gtgtattctt tggcttttct aaaacttttg ctcctttgat cacagaaagt
    10981 ggctttgagt atcatttact agcgccgatc cttacgaaaa aacaagaaga acaaatcata
    11041 aaatttgacc agttgcgtac acttaaaaac ccttttacca aagaaatggt tgcctctcgt
    11101 atcactagtg aacagagtct gattgctaag tttgagcctc gactgattgt gacaggttcg
    11161 aatgtgacaa tttttttatc ggcccgcaat aaaaagattc ctttagtata tgttaaaccc
    11221 tatgctttga gtgaaccttt ttttcaatca gagcatgcgc tgatgcccca cgagttacgt
    11281 ttcttcggcc ctttaagcaa tcccctttgg cactggacaa aaaagcgtat agtaaatacc
    11341 cgatggatcc ccaatgcctt caaacacgct gcacaaaaag aaatgcttcc tttaccaaaa
    11401 acaagtttac aaatgatgga tgctgatcta aatctcatca caacgcctaa actatttttg
    11461 gaagaagaac agctgccgga aaattatcga atcgttggtc caatttttgc taagctcagt
    11521 acttccttgc ctgaagaagt gctaactttt atacagcgaa agcaacaaga aagaaaacgt
    11581 attatctatt tcgcaatggg tagttcaggc aatccgcgta tgttacgcaa aattttgttc
    11641 ttcttacaaa aacaaccgga tctagcggtt attgcaccta ttgactatct gcttgatgac
    11701 attcaatctg actcagaaga tcttttaata acagaatatc tgtctagtca tcttttgcat
    11761 gaattcattg atttttcttt tatccacggc ggggaaggga ccgtccaaac tgcctgtgaa
    11821 tccggcaaac cgtttatcgg tgtggggatg caatttgagc aaagctgtaa tattgactat
    11881 tgtgtaaaat acggaaacgc aatcgccctc acaaaaccag tgactgaaag aaaactgcag
    11941 attgctctgc gcgaagtttc ttcacccaag attcgtcagc aggcacgcac gctgcaagcc
    12001 gtttttccaa taaatggtcc acaacaagca attcaagaaa tcgaaacctt cctgagcaac
    12061 cacccaatat agtttcaagt agaaaaagct tttttaatag agactcatca gtaatttcgc
    12121 tattcgagac ccagacagtg aaaatacaaa aaaagtaaat agtggattga aaagttagag
    12181 ttacttaaat tacggtgtct aaaaaacaca aaatcatcct taaaataaaa gatctgacgc
    12241 aatccaaatg agcataggta gcgtctgcca tttattctta gtcaaattct ttgacacctt
    12301 tctctggttg gatcatctca acgtttcttc aaaagaaaga ccataataat taggcaaata
    12361 cattttctta aaatgtgtca tatagatcta gaagcatcgc tttgtagaga tttgtgctgc
    12421 tagtcccttc aacaattact aaatcaaatg taggatttac cactttatct ttgataatca
    12481 acctccctct tctgttgaga caatgatctc gcaatccgat gcatactcct atataaactg
    12541 ccagcaatcc ccacatgctg agtagatcat gtcagaatgt tctatgtcgt cagcaacgat
    12601 aaactaaaag tcacgttcac catgactgat tgctattccc agcgcaatta tttctataca
    12661 cgtttcatga tttgaataaa cactctcatc atacatatta ccattcatac accatactgc
    12721 agcccctact atatggttgt aagctcccaa atctatattt gccttgatca ctttggtagt
    12781 agatcgacta attcttaatc cattgctgat aaaattttca tttttgcctc cttctttctg
    12841 ccaaaacagt taaaacaata ataatcttta tgtaaaaaag ggctgtgaca aaagccttgt
    12901 cacagtccca tattccgaat aaacggtggt caaaagcttg catctgcggt aataagttca
    12961 accaaacgaa aaataagcca acatttcaca aaaatttaag aagcaatttt cgtaaatttc
    13021 ttcttatttc ttgaagctaa ccacttctgt cacaaccact tttagaacat ttaaagcttc
    13081 gatgtgacaa accatctatg ctgctcgatc ataaaattga tagcaaaaat tccacaaagt
    13141 acatatgtcc cccatgaaaa caaaacattc atatgcggta caatgatctt tggaagaatc
    13201 acgatcaaaa atgatgccag tgcccaaatc catcgattga tttgaatatg atatgtagct
    13261 agcatattca atataaggtg actagccgtt aataaaaaga taaaaacaaa aaataaaatc
    13321 agccaataca ttgtttccca ccttctaaaa accaaactta gacagtttgg acttcgtttt
    13381 ctccacgact ttgttcatct gacagcatct ttttatcata agcttttaca aatggataat
    13441 agataataaa tgctatcaat gtgttgatca tgatcaagat aacaacacgc cagtcatttc
    13501 ctgctgaaag ataaccgccg attggagctg gtaatgtcca agttggcaaa acagtaaatc
    13561 tattgaccat ttctaatttg actgcaaaat aactgataat agtcaaaact aaaggaacta
    13621 agttgaacgg gatgaacatg taaggattca acatcatagg agctccaaaa atcatgggct
    13681 cattgatatt gaagatacca ggaataatag aaaaacgacc aacctctttc aagaattttg
    13741 atttacagaa gaatataaac aaaacagata ccacgatcgt tgctcctgca ccaccaattg
    13801 ttaccgtcca ttgataaaac tgttcaggag cgatataggg taattgggtg gcagctgtac
    13861 catctgccaa tgcctttgca ttctcatcca acatgatcag ccacattgga cgaacaacag
    13921 cccctacaat actcatgcca tggataccaa atgaccacaa caaatggatc aaaaacattg
    13981 gtagtaaaac accaagcaaa ttattcccta aaatattggt taaaggctcg aataacgata
    14041 ataaggtagc gtttacatca aagcccgcga cgcttcgaat cagccaagta attgttaaaa
    14101 tgactgcacc tggaatcaat gcctcaaaac tacgggcaac agcaggtggc acttgttctg
    14161 gcattttgat agtaatattt cgatttttaa agaaacgata tacttccact gcaaaaatca
    14221 tagataagat ccccgcaaac atcccagatg ctcccaaaga actcataggt aagacccagc
    14281 caagaggtgc cttttcagga gttaaaacgt ttacaggaac ttgtaacata aagaacgttc
    14341 ctaaagataa tataccacct gtcacactat ctaatccata tgatttagct agatccgaac
    14401 ccataacaaa agttgcataa atagccatca atcccatcgt catcctaaaa ggtaaaacaa
    14461 tcgttgccga ataaggggca ataaattcat tccatccagg aaacggtaaa ttgataaaga
    14521 ccataaaaaa tgtcccaatc aaaatcaatg acaatgttga aacaacccca ttacgaattg
    14581 ctaataaatg acgctgtgta ccaatttttg ccattggtgg gacaagtttc tcttcgaccc
    14641 atttcatcag cttttccact aaaaccactc cttttcaata aaatatgaac cattcattgc
    14701 atgacaacgc aaagaatgtt cataactaat tatataatta agaaatttta tttcaatata
    14761 ttctcttaaa taatcaaatt tatttttaag aatcctgaaa ataagttttc taaatcatag
    14821 gagcaacaaa aaaattcgat aattaacaaa
//
LOCUS       DAFKHN010000058        14830 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFKHN010000058 DAFKHN010000000
VERSION     DAFKHN010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.058"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            316..675
                     /locus_tag="LY912_001961"
                     /pseudo
     CDS             316..675
                     /locus_tag="LY912_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(970..2103)
                     /locus_tag="LY912_001962"
     CDS             complement(970..2103)
                     /locus_tag="LY912_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBM6955629.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            complement(2094..2762)
                     /locus_tag="LY912_001963"
     CDS             complement(2094..2762)
                     /locus_tag="LY912_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6955630.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(3218..4204)
                     /gene="lacD"
                     /locus_tag="LY912_001964"
     CDS             complement(3218..4204)
                     /gene="lacD"
                     /locus_tag="LY912_001964"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBM6955631.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(4217..5143)
                     /gene="lacC"
                     /locus_tag="LY912_001965"
     CDS             complement(4217..5143)
                     /gene="lacC"
                     /locus_tag="LY912_001965"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBM6955632.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(5156..5671)
                     /gene="lacB"
                     /locus_tag="LY912_001966"
     CDS             complement(5156..5671)
                     /gene="lacB"
                     /locus_tag="LY912_001966"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBM6955633.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(5690..6118)
                     /gene="lacA"
                     /locus_tag="LY912_001967"
     CDS             complement(5690..6118)
                     /gene="lacA"
                     /locus_tag="LY912_001967"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBM6955634.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTRKHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(6138..6911)
                     /locus_tag="LY912_001968"
     CDS             complement(6138..6911)
                     /locus_tag="LY912_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBM6955635.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            7076..7555
                     /locus_tag="LY912_001969"
     CDS             7076..7555
                     /locus_tag="LY912_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6955636.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            7612..7914
                     /locus_tag="LY912_001970"
     CDS             7612..7914
                     /locus_tag="LY912_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBM6955637.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            7936..9393
                     /locus_tag="LY912_001971"
     CDS             7936..9393
                     /locus_tag="LY912_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBM6955638.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(9986..10738)
                     /locus_tag="LY912_001972"
     CDS             complement(9986..10738)
                     /locus_tag="LY912_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBM6955639.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(10953..11189)
                     /locus_tag="LY912_001973"
                     /pseudo
     CDS             complement(10953..11189)
                     /locus_tag="LY912_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
     gene            complement(11199..12157)
                     /locus_tag="LY912_001974"
                     /pseudo
     CDS             complement(11199..12157)
                     /locus_tag="LY912_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(12363..14045)
                     /locus_tag="LY912_001975"
     CDS             complement(12363..14045)
                     /locus_tag="LY912_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBM6955640.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
     gene            14183..>14830
                     /locus_tag="LY912_001976"
     CDS             14183..>14830
                     /locus_tag="LY912_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HBM6955641.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVST"
BASE COUNT         4391 a         3168 c         2533 g         4738 t
ORIGIN      
        1 tataaataac tcataaaaaa tattttgact ttcaaaatca cttttgctac cagaagttga
       61 ggcgaagtgt tttaagcata gttgtaccct agtttgaccg ttaaaaataa ataacgatcg
      121 ctagagtgca actatgtttg tttgccctac cgtcagcgtc ggcttggcct ctcacatcca
      181 ttaccgtcgg gattatctcc gttacatacc cttacaaaat acgccctgta agcattgcat
      241 gaaaccaccg tgcatttgca ccgtatttcc gccctagccg ttcaaatcgg tcgctaccac
      301 cattcagaaa cacgtgcggt aatggaaggt ttggaggaag ctatccagac cactaacgat
      361 tgtccctatc gtcgtacgtt tcactcagat caaggttggt cgtatcaaat gaaagcttat
      421 agaaacaaat tgaaggagta caaaatcttt caaagcatgt ctcggaaagg gaactgctta
      481 gataattcac ttatggagaa tttttttggc ttattaaaac aagagatttt tcacgggaaa
      541 gtttataact gtttcgagga attaaaatca gccatcgata gctatatcta ttactacaat
      601 aatgaacgga taaaacagaa attaaactgg caaagtcccg tccaatttcg taaaacaacc
      661 gttacggttg tgtaaaaata tcattttaga gcatgaaaaa aagagtggat ttctccactc
      721 caaaaaagtc taacttttgg gggtcactac atttttgatc ctttttattt gattaattat
      781 atccagctgg ataataattt tgggggcaac atttctatct tactattatc ttcctaaagt
      841 agtagacttt cttattggga aaaattacaa caaaaaggag tggcttagtt gacaactcct
      901 ttttgtttac aaatcaattg gatatctata aattgtattt tctaacgaat tttatagaca
      961 tctgatttgt caaattaagc tagacaatat gtctttatct atgcagctca aaaatacttc
     1021 caatggtgtt cgataattta atgattttct tggaatatgg tttcttttcg aggcaacgga
     1081 ttgaataaag gtttcatccg tgtccctaaa gtccattgtt ttaggtaagc catcctgctt
     1141 gagcccatgc actcggtact gatgagaaaa aattgatgcc tgtttctcct gaggaatgcc
     1201 aattccctga tcttttactt caataatcac gctacccttt tggtttgaaa tggtgacaat
     1261 taccagtttt ccttcaccat atttgattgc attgtcaact aaattcgaaa ccgcccgata
     1321 aatccaacga tctcgtccat gaatcagggt tggttgatct tcagtaaacg caaacaaaag
     1381 attcggataa ttcattttgt aggcatcaca aacttccgca cagatcagtg aaacgtctac
     1441 gacttccgtg ctaagatcct ctgagttatt ggataatgtc aaaatatcgt caatactgtc
     1501 ggtcatccga tctaaaagca ttaaatttcc ttgatcggca tgttgccgtt ctatttccag
     1561 attcgtacgc aaaatagcga tggcattttt ctgctcgtgg gtcagataac tatttaatcg
     1621 tcgataatcc tccaaatgac catcgaactt atcctttagc ttattaaaag ccgcatttaa
     1681 tgcctcgtcc ttcacagtat ttttaggaac ttgatcaata aacgttaaat cacgcgtaat
     1741 cgctaagatt tgattactgt aaattttgcg taaaaccaac caaagaataa acgttaataa
     1801 catgacggca gaacaaataa ccagcaccat cgctggtaaa tatttaaata gttcgtcctg
     1861 gtaagcttta tctatcatcg aaatagtcat aaattgattg ttggaagatt tcgaagcttc
     1921 catctgcgtc tctgcttgaa ccgtcttacc ctcttccata aaataaacat cttcacctaa
     1981 ggtagatgcg atactgattc cctccaaatt atttctcaga aagaagaaac tcactaaaat
     2041 cacgcctgtc accaacagtg aaaaagccag catcgttaac gtcattttaa aatttaatag
     2101 catagctggt acccctttgc tcgaatggtt tttaagacct ctttttcagc tgcttcagcc
     2161 agtttctttt ttagacgagc cagatgcact cgcagaaccg acgaaaaagg atcaaaatct
     2221 tcatcgtaga catgttcaga aatttcctca gacgaaacaa ccgctggatg acgctgagcg
     2281 atgcacagta agatatcaaa ttccttgggt ttcaggacca cctctgtctt ttgatagctg
     2341 acccttcgac ctaatggatc aatcttcaaa gcaccaattg aaatctgcgg cagcgcacgt
     2401 ccatgataac gacgaataac cgcgcgtatt cgtgctttta attctagtaa ctcaaagggt
     2461 ttgactaaat aatcatctgc tccaaaatcc aagccttttg ctcgttcttc aatctcatca
     2521 cgtgcagtaa taatgataac tggactttcg acttcttcag cacggagact ttgtaaaaca
     2581 gataatccat cttttttagg cagatttaaa tctagtagta tcccatcgta tgaattgatg
     2641 aaggccttct cttctcctga ctcgccatca taagctacat ctacagaaat attctcctgc
     2701 tctaggccct tttttacgga taaaaccagc tcacgattgt cctcaaccac cagtacacgc
     2761 atgtatattc actcctcata cggatttagt aattacactt atgcttttta gcatagtaca
     2821 cgctcttctt caaagtccac gttctttttg tgaagatttg aagaaattca tacattctgt
     2881 taaaaaacac ataattaaga atgattttac tgtttgaaaa tacctagaat agaaaaagac
     2941 tggaaccttt cctccagtct cactactttc tatttgcttg gttttcttgt atatactttt
     3001 caaagttcgt tggtttatga ccaataagcc tcgttagaat actgaaaatt gccatcaagt
     3061 cattaagtac cacatgtaag aaaatctctc taaagaaaaa ccccttcgtt ttaactcact
     3121 tactatttta gaattcgttc ccctaataat gcagcatgat tttacgcttt atgtataaaa
     3181 aaagactgca agcaattttg cttcacagtc tgatttctta tgatagtgag cttgttaaca
     3241 cttccaccgg tgtagcagtt tctttcaata cggcatttaa ttcttcaata tttttacgcc
     3301 cttgcgtatt catccactcc atcgctgctt cttttccatc aacgatatag ctttctacac
     3361 catctgccca agtcgcacgg ccgcaaagta caccattgaa ggttgagccg gcatttttcg
     3421 cgaagcgcag tgtttcttgg aacaactctg cttttacacc ggcgcttagg aaaataaatg
     3481 gcaggttagt ggcttcagcc tgttccttga agaagttagc cgcttgtgcc tttgtgtaca
     3541 cgacttcgtc tgtcccatag ccttccacat aattcatatt gacgggtact tccaccttta
     3601 acacatctac gccataacgt ggatcagaaa attccttcat catatcgttg actttatgag
     3661 gtttcttaat ggcgtattct ttcgaagtcg catcagagat gttcgcgtca taagaaacaa
     3721 gctccaagaa gaagggtaag ttttcagcct gacattctga gccgattcgt tcaataaagg
     3781 catgtttttg attattgatt tcttctgctt catcgacatc atagtaaagt aggaacttac
     3841 aagcatcggc gcctgcttct tttaaacgtt taactgacca gatcgataat aaatctggta
     3901 aacggccggg agttgacgca tcgtaaccag ttttttcata agctaacagc aagccggcat
     3961 tttttgctct aacgtcagct gctggcaagc catattcggg atctaataaa atcgatgagg
     4021 catatttcgt taattgtgaa gaaacaattt ctttaaattc aacgatttct gattcttctg
     4081 cttcgctgcc cttgaatttt gtgatcatct tcttcaaagc cccgcgttga tcaattgcta
     4141 aggccccaat cactccatct tcattgcata gttgcttgat atattgacgt ttttcttcgt
     4201 tcatttccgt atcctcctac actttctcca ctaagatttg atcatatagt ttttgataat
     4261 tggctaattg gacatagcca gtcgtcgctt cctgagcatt cagcattcct aaaacattac
     4321 cctgttttaa cacggcttca tccgaaagac cttgttgaat cgcagcggtc aatccggcaa
     4381 cggtcgcatc accagagcca actggattga cgacatcaat ctttggaatt gtcacgcaat
     4441 aaaaagtctc gtgatgtttg gcaaaggctc cgtcgccccc cattgaaacc actatccatt
     4501 caatttcatc aaacatcgaa tctgacaagg cggcttttaa atctgataat tctgttgaga
     4561 tttctcgtcc tagcagacca gccagctctt cggtattggg ttttattagc ttaggcttta
     4621 cactgcctcg caacacttcc cttaatgctg tacctgaaca atctaaaacg acaggctttg
     4681 gctgacaaac ttgcagcatt tgtcgataaa aatcagcagg caatccttct ggcaagcttc
     4741 ctgaaaaaga aatgatttcg gctttaacag ctaatttttc gaaatgttgc aagaacgccc
     4801 ttgcttcttg ttcagtaata acaggtccgt tttctaggat ttccgtctgt tttccgtcat
     4861 gtaaaacagc gatgcaatta cgtgtctctc cgctgatagg taaaaagtca tgagcaatct
     4921 cattttgagt caggtccttt ttaatctctt cacctaaaaa accgccgatt aaaccactag
     4981 caatcacctc cgtatctaat tgcttcaaga tacgtgtcac atttaggccc ttaccgccag
     5041 ctgttttgcg aacatttctt actcgattga ctgtgtcgag cttgaaggtt tctaatggat
     5101 aagaaatatc aatcgatgga ttcatcgtta ttgttaaaat catttgtcca cccgcttaat
     5161 cgtggtattc gccacgatcc catttctcga taaattcatc gaagaaatgc ggatcagact
     5221 gcttgtcact ggctttttcg acgtgatcga ttttggcgat caattttttg ttttcttcag
     5281 tttcttgata atcggcattg atgaaggcct ctaatatgtc acagatcaaa aattctcccg
     5341 taatccgagc gccaaagccg atcacattgg catttagttg ttccttcgca tagatagcag
     5401 tcgtcatatc gcgaaccagc gcactgcgga taccaggtac tttattgaca gcgttgttaa
     5461 tcccaacacc tgttccacac aaacaaactc ctagatctgc ttctccgcta gtcacggcct
     5521 ctccgacttt ttttccgtag atcggataat gggttctggt aaagtcatag gtccccatat
     5581 ccaacacttc atgtcctttt gattttaaga aatctgatac tgccattttt gtatctgtga
     5641 cgatgtggtc acagccaatt gcgattttca tttcattcat ccttcctaat tacgccattt
     5701 tatttaacat gtcgacacgt acttgatgac gaccaccatc ataatttgct tgtagaaatt
     5761 ccttaacaat attcaacgcc aactcatcgc caacaatttt tgatccaagt gtgatcatcc
     5821 gagaattatt atgtttacgg gtcatatacg cactgcgctc atccgaaact tctgctgcta
     5881 ccattccttt aacctttgtt gccgtgataa agctgccagc gccgtagcca tcaaccgcga
     5941 ttcctaaact accttcgttt tcattcagat catttgcgat cgccaaagtt gattccacaa
     6001 aatcttctga agccgtttca ctcttatcta ctactgtaat accttctttg atcaattttt
     6061 tcttgattaa ttcctttaat tccatgccgt cactgtctga accaattact acacgcattt
     6121 ttgtttcctc ctatttttta ctgaatgatt ttagtgaatt gctgataata actcttcagc
     6181 tcggctgaaa gagtagaatc cgtaaataat ttgtcgatct tgcgcaaatc atagaaatta
     6241 taaaaatcgc tatggtcgaa tttgtttgca tctgaaacca aacatttttc tgccgcatta
     6301 tctaaaacaa ttttttgcaa ggtaccttct tcaatactga aattcgaaac ctccgaaccc
     6361 ttcaatccat tcactccgac aaaagccttc ttaataccga ttttttgaac agcttcattg
     6421 gcaattgaac cgacaaaggc tccagtcttt tcccgatata gcccaccgat caaatacagt
     6481 tcaaatcttt ttatttcact taatagattg aaaaccggca gactattggt aacgattcgg
     6541 agagatgacg gcttgatgta tcgtgtcatt aattcgatcg ttgtacccga tccaagaaaa
     6601 atcgtgtcgt cttcttgatt gatatgagct gccgcatttt tagcgatgta ttccttctct
     6661 tttgtatgca gcttcttttt ttcagtatga gaaagctcat ttgcttctat agaagtcgac
     6721 atttccagat aatcgatttt ttgtgcaccg ccatgaacgc gtaaaagctt tttcttctgc
     6781 gcgagttcct ctagatctcg gcggatcgtc atatctgaaa cattcagtac ttcctgaata
     6841 aatttgactg ttatcgtccc atagcgatca cacatcgcta agatcgaacg ctgtcgttct
     6901 gttttcagca tattctgtac ctccacgacc ttataataaa acatttacga acatttttca
     6961 acacatattg ttcgtttatt ttcgtttatg cgttgacaat gattttgtaa gcggttatac
     7021 tcaacttgta aacatataaa taaacataaa cgaactaata aaggagctgt tttgtgtgaa
     7081 tgaattcttt ttcaaagaca ctgtctatgt ttctgacaag cagtcgcagg aagaagtgtt
     7141 cgaggaagtc tatcaagatc tgttaaagaa agaattggta accgaagatt ttttggagaa
     7201 ccttttagaa cgggagcgta attatccgac gggattagat ctctcacctg tctctaaaat
     7261 attgccagat atcgctatcc ctcataccga aagtgagttt gtgcgaacca cccgtatcat
     7321 tccaatcaaa gtaaaaaatg aaatcccttt ctacaacatg atctcgccaa gcgatcagat
     7381 ttccgcttca tttcttttca tgatcttgaa cgaaaatggt gaagcacagg ctggcatgtt
     7441 ggctaatatc atggatttca ttaattctgt tgacgaagaa aaactgtttt cgtttttcaa
     7501 attagaggac acagaagcga tttatcattt tttagaagaa catttttata tatagaagtc
     7561 tctgcctaac cgcaggataa aaaataaact tattttaagg ggagaattat tatgatcaaa
     7621 attttagcag catgtggagc aggcgttaat tcaagccatc aaatcaaaag cgctttggaa
     7681 actgaattga aaaatcgtgg ctatcaagtc acctgtgacg ccgttatgat caaagatatc
     7741 aatgaagaaa tgctgtctca ttatgacatt ttcgcacaaa ttgccaacac cgacttgggt
     7801 tttgacatta acatccctgt cgttgatgca ggtgctattc tttatcgtat tcctgctatg
     7861 gctgagcctg tttaccaaag tatggaaagc gcaatccaat cattaaacaa ataggactaa
     7921 agaaaggaaa agcatatgaa tacaattatt gatattgcca ataaagtatt taccccccta
     7981 attaatttag gtgcggcacc gttaatgacc atcgtattaa ctgttattgc tttatttttt
     8041 aaagtaaaac cgtcacgcgc tcttgaaggc gggctcaaat tagggatcgc cctgactggg
     8101 atcggagcta ttattggaat tttaactact gctttttcag acgctatgac agcttttgtt
     8161 gaacgcacag gtatttcatt aaacattaca gatgtcggtt gggccccact agcaaccatc
     8221 acatgggggt cgccatacac gctttatttt ttactaatta tggtgatcgt caatattgtc
     8281 atgttagcaa tgaaaaaaac caacacatta gatgtggata ttttcgatat ttggcattta
     8341 gcaattgttg gtttgttcgc gatcttctgc ggtgctaatc tgtttattgc ttctgcatta
     8401 gttattttca ttggtgtatt aaaaatttgg aactccgact taatgaaacc aaccttcaat
     8461 gacttgttaa atgcgccaga cagcaacccg atgaccacga ctcatatgaa ctacatgatg
     8521 aatccgatta ttatggtttt cgataaaatt ttcgacaaaa tcttcccttg gttggataaa
     8581 tatgatttcg atgctgccaa attgaatagt aaaattggct tctggggatc aaaattcgcg
     8641 attggaattt atttggggat ttttgttgga ttactagcag gacaaacacc aacgcaaatt
     8701 ttctcgctag cctttaccgc tgccgtctgt ttggaattgt tctctttgat aggcgcttgg
     8761 ttcatcgcag ccgtagaacc gttatcacaa gggattaccg attttgccaa taaacgacta
     8821 aaaggacgta ccatcaacat aggtttagac tggcctttca tagcaggccg cgctgaaatc
     8881 tgggctgccg ctaacgtatt agcaccaatc atgttgctag aagccatcat cttaccagga
     8941 aataaattat tgccactagg cggaatcatc gcaatgggtg ttaccccagc actattggtc
     9001 gtaactcgtg gaaaattaat ccgtatgatc gtaatcggcg cgatcgaatt accattattc
     9061 ttatggtccg gcaccttgat cgccccgttc gttactcaaa cagctaaagc agtcggagcc
     9121 tttccagccg gcttgaacgg gtccgccatg atctctcata caacgatgga aggcccgatt
     9181 gaaaaattcc taggttattt agtcggtaat gcttctcaag gacaaatcga atttgtgata
     9241 tacgctgcct tagcattagg tgcatacctt ttaatcttca tttggtacgc tcgtcaaatg
     9301 aaaaaacgca acgctgcata cgcagctgaa aaagaagaga atgcatctcc ggcaacggcg
     9361 cataatatga cttatgcagc cgaagctaaa taagctaaaa acaccccgaa tgtctttaga
     9421 cttcggggta ttattttacc tataaaaaat aaatagatgt aaaatccatt tcaaaaagca
     9481 tagcccatct cttgccacac ccaataaaga aattatcaac gtttatgctt tttttaactc
     9541 ctttaagctt gcctttgttg gtattcctca acgattcttt ttgtgttctt gtttgttttg
     9601 tgctttttga ctttttgttg tttaattgcg aattccttga tttctttttt cctgaatcgc
     9661 ttcgcatccc gcggttatgc gtgcgatttc atcattgctt tttctgatct aactcgtttc
     9721 atgtcaaaga gcttcagctg acttagtgtc catggttgtt ttgatatccc ttttcctcct
     9781 taataaagcg gtgattgata ctgctatttt ttccttcaca taaacataac atcccaaaaa
     9841 aatcgactat cttttttcaa atggtgtatt caagtattcg gaggaattag taatgatgca
     9901 ccctaaaaat aacataattc gcttaaattc aaggctacca aaaaactacc aagttctaat
     9961 tatctagagt ttggcagttt ctcatttaca caacatattt ttcttctttt tcgatttttt
    10021 catagtgctt ttgttcatca tcatccgtta taactactgt tacatcattc agattataat
    10081 atactgaaaa atctcttttc ccaattttcg aatgatcaat caataaaaag cgttcaacag
    10141 aattattcag agcgatctgt tgagtttggc cctcttcaaa agtcgaagtc ataattttct
    10201 gttcatttaa agcattacag ctgaaaaatg ctttatgaaa attcatatcc tgtagcgatt
    10261 tattcgtgat ttcaccaaca aagcattgag tcgtttcccg catctcgcca cctaatagat
    10321 agatttttcg attccctttt cgcttattta attcttcaaa aacaggcaaa cagtttgtaa
    10381 caatccgcag tgaatcccct tgaatgattt ttgacatgag ctcgattgta gttcctggtc
    10441 caagaaatat cgtatcacca tcattgatca tttcattcgc cttttccaca atccgctgct
    10501 tttcttcttg cagcataatc tgtttttctc tatgagaaag ctccacatgc cgataaaaat
    10561 ccttcaattt cgctccgcca tggacgcgtt ctaataatcc ttgtttctcc atttcgtcca
    10621 aatcacgtcg gactgtcata tccgaaaccg aaaacttctc cataatatcg ctgactcgta
    10681 ctgtaccgtt aacctctaat aacgacatga tcgcttggaa tcgatccgtt tttaacattt
    10741 catcgcctct tttcttttta agactatcaa attcttaaga aaagtgctag aacaagtttt
    10801 cttaagaagc cttctgcagg aaggaaagca aaatttttca gaatttgcaa gctgctattc
    10861 taaaaaataa aaccgaacga gcatgactgt catagtgaca gccttgttca ttcgactttt
    10921 atctttaata aatcatttta tttaatctga agttattgtg caagttcaaa aacaaagtag
    10981 ttaatgtctc ctcgatattt cgaaatcgaa tactcaacgg gcagacgttc tagcgaaaaa
    11041 ccctgtgtat ggaaatagaa cattggatct ccttcttcca catctaacaa atcgctgatc
    11101 gtatcatccg ctttgattac ttctagtttt ctggtgaccg ttttaattgg ataacccatt
    11161 tcttcaaaaa cttgatacat tttttctttt ctgatttgtc aaattaagct agacaatatg
    11221 tctttatcta tgcagctcaa aaatacttcc aatggtgttc gataatttaa tgattttctt
    11281 ggaatatggt ttcttttcga ggcaacggat tgaataaagg tttcatccat gtccctaaag
    11341 tccattgttt taggtaagcc atctcgtcta agcaagccgt ttgagtgctc atttagccct
    11401 ctttgcgaag gtgttcctgg atctgcgaaa aagatggcaa tatcgttcga gttacttata
    11461 gatcgccagt tggaaaattc ttttccacaa tcaaatgtca tggatttaaa caagtgttta
    11521 ggcatggatt tgaaccaatc atttaacctg ttttcgatat cttcggctcg tctgcctgtc
    11581 ggtttcaaag taataataac cttggataaa cactcaacca atgtaataac agcgctcttg
    11641 tgtttaactc ccacaatggt gtcgccttcg agatgaccaa attctttagt caggtgtgga
    11701 tagagactgt tccgttcatg aatcgttctg cgaaaggcct gttttccacg cttttcttga
    11761 tgattattcg gtttacgttt ccccttcata ggtaacgact gtgtgtcaaa aaggcctttt
    11821 ttaaacatcc gatagagtgt acgaacagaa caatcaattg gaaactcgcc acggccgata
    11881 atcacatcgg gtgaccaccc ttgagctacc ttttcttgaa catatgttga ttgttcatca
    11941 gataaaacgg ttgaacgtcg tccacaacga gatttatttt gtttgtattg acggtaataa
    12001 tctagcactt ttttccttgt ttgagaaacg aataaacatt ataaatggtt tgtctagagc
    12061 gatttaaact ttgtgcgaca agagcgacag gtttctcgat attgaaataa gactctatga
    12121 ttactagttc gtctgttgta agatgggtgt aggtcatttg tactcactcc ttattaattc
    12181 tttggtcgga actattttga gtgtagcaca aatgatcttt ttagttgtct agcttaattt
    12241 tacaatcgac gcctcaaaaa gaatacccga aatttaaaca gcaaaaaaag atagcgctta
    12301 ccattgtgtt taagataaaa cgctagctaa gttggctagc gctttattaa tctaagcaag
    12361 ctctaaaatt gcttcaatac aaaatcaact gctcctttag gatcacgtgt taaattgata
    12421 tattctgcac ctttagttgc aattactttt atccctaatt tgtctgcatc tttacggaga
    12481 tcatccaaat aggaattcac ttgaggtgct agaacgatta aatcaaaatt tttcatcata
    12541 tcataatgag aaccataagc tcctgcttta gcagaaagat taacacctgt ctcttttgcg
    12601 ccctcttcta atgcattagc caacattgca ctcgttccgg caccagcaca aagtactaaa
    12661 acgcgctttc cttcaccaac cgatgctttt gcttcatcaa ctataactgc cgcagttgca
    12721 ccaacttctt ggatttcttc gaccaattct tcttttactt cttctgcagc aatgtttttt
    12781 aactcttgtt ctactaattc agaatcatag gccttaacaa aaggtaaata aataatcgca
    12841 tcgacaacaa tcaatactac cgctaataca atcgccaaca cactaaaccc ggttcctaaa
    12901 accaagccaa tcggtgcggg cgtcgcccaa ggcaatacgg atataaagct attcatcccc
    12961 aagacatcga caaaaagttt gaatatccat acgttagcga ttggtgctaa taaaaatgga
    13021 attagaaagt acggattcaa aataatagga gtagcaaata gtaacggttc atttaccgca
    13081 aacgaaactg gaataaatga agctttacca actgctttca attgttttga tttagcgaac
    13141 aacatgaaca gaaaaggaac aactagtgtc gctccagtac cacccatcgt tccaacaaag
    13201 tttcctagac caactgttaa tacttttgag gcttgtgcac cgtttttaaa taattcaaag
    13261 ttagtttcta cgttcgcata aataattgca gcaatcgctg gttcaacaat cgatggtcca
    13321 tgaacaccaa caaaccagaa cattgccatg gctccccaaa tgattgcaat accgacatat
    13381 ccatcagcag cactaaataa tggctgcaat aattgaatta cacctgctgc aaatgatgtt
    13441 ccaaaaaatt gacgaactcc cgtatcaatc aaaacggcaa taaatactgc aattgaaaag
    13501 gggataatat ctctaaacat ctgtgtgatt gttccgggaa cttcttttgg catacggatc
    13561 gtcaaatctc ttttaacaca gaatttatac acatttacag taacaaacgc agaaacgaaa
    13621 gctgctaata atccctttgt ccctaaataa tcagtagcta tcccaccatc aatttgatca
    13681 gctgccatca ttacaaaacc acaaattgac gctaacataa cagaaacttc attaatctgc
    13741 ttacctgaat cagataattg acggttcatt gaattagcta aacatcgagc tgttgtagca
    13801 acaaccaaaa gaccaactaa tcccattgaa taaccataaa ctttccaaag ccacgtcgag
    13861 aatgcctctg gtaacgtcac gttaaatact tctggaacag ccgcaatcat aataaaaata
    13921 cttgaaaata gaatagctgg catagcagtt aaaaagccat cgcgaattgc ccctaaataa
    13981 atattacgtg agattttttc aaaaaacggt tttcccttct caatttgctt aataatcgta
    14041 ttcatttttc ttctcctatg ctttagcaaa tttttctttg tacaattcaa caaaatcatt
    14101 gataagttcg gttctgttgc aaagttttcc aaaaaatcta ttttagtgta aaattgagaa
    14161 aaaagacaga gaggacagag taatgaatca ttttaaaggc aaacaattca aaaaagacgt
    14221 cattattgtc gctgttggtt actacctgcg ttacaatcta agctatcgtg aagttcagga
    14281 attgttatat gatcgtggaa taaatgtttg tcatactacg atttatcgtt gggtacaaga
    14341 gtacagcaaa gtcctctatt atctttggaa gaagaaaaat agacaatcct tctattcatg
    14401 gaaaatggac gaaacctata tcaaaattaa gggacgttgg cattatcttt atcgtgcaat
    14461 tgatgcggac ggcttaacct tagatatctg gttacgaaag aaacgggata cgcaagcagc
    14521 ctatgctttc ttaaaacgac tccataaaca gtttggtgag ccgaaagcaa ttgtgaccga
    14581 taaagcacct tctcttggct ccgcctttag aaagttacag agtgtgggtt tatatactaa
    14641 gacagagcac cgaactgtga agtatcttaa caatttaata gaacaagacc atcgacctat
    14701 taaacgacga aataaatttt atcaaagtct ccgtacagcc tcttccacga ttaagggcat
    14761 ggagaccatt cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct tcggcttttc
    14821 ggtgtctact
//
LOCUS       DAFKHN010000059        14781 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFKHN010000059 DAFKHN010000000
VERSION     DAFKHN010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.059"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            285..2024
                     /gene="yfcC"
                     /locus_tag="LY912_001977"
     CDS             285..2024
                     /gene="yfcC"
                     /locus_tag="LY912_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBM6955642.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2181..3365
                     /gene="iadA"
                     /locus_tag="LY912_001978"
     CDS             2181..3365
                     /gene="iadA"
                     /locus_tag="LY912_001978"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBM6955643.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3476..3679
                     /locus_tag="LY912_001979"
     CDS             3476..3679
                     /locus_tag="LY912_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBM6955644.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3780..4442)
                     /locus_tag="LY912_001980"
     CDS             complement(3780..4442)
                     /locus_tag="LY912_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955645.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4455..5957)
                     /locus_tag="LY912_001981"
     CDS             complement(4455..5957)
                     /locus_tag="LY912_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955646.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6505..8184
                     /locus_tag="LY912_001982"
     CDS             6505..8184
                     /locus_tag="LY912_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBM6955647.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8311..8790
                     /locus_tag="LY912_001983"
     CDS             8311..8790
                     /locus_tag="LY912_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBM6955648.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            9009..9689
                     /locus_tag="LY912_001984"
     CDS             9009..9689
                     /locus_tag="LY912_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBM6955649.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9697..11028
                     /locus_tag="LY912_001985"
     CDS             9697..11028
                     /locus_tag="LY912_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBM6955650.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            11043..12005
                     /locus_tag="LY912_001986"
     CDS             11043..12005
                     /locus_tag="LY912_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBM6955651.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12116..12454
                     /locus_tag="LY912_001987"
     CDS             12116..12454
                     /locus_tag="LY912_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBM6955652.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12533..13240
                     /locus_tag="LY912_001988"
     CDS             12533..13240
                     /locus_tag="LY912_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBM6955653.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13405..14700)
                     /locus_tag="LY912_001989"
     CDS             complement(13405..14700)
                     /locus_tag="LY912_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HBM6955654.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIKVR"
BASE COUNT         4687 a         2607 c         3182 g         4305 t
ORIGIN      
        1 aatgaaattc aatttttcaa tgattgtaaa atgaaaaaaa caggacgaga ttttctctaa
       61 tctaaaaata aaaaaagaat tttaaggaaa aacagagaaa taaaatactt aatataaatg
      121 gaaagagaaa aaaataatca tacataggag aaaaaaagca aaatagaaaa aagtgatttt
      181 ctaataaatt attcatgtgg aaatgtcatt tttactgtat aattcatttg attatccatt
      241 ttttattcat caaaattact gaaaaaagaa aggaagaaat aaatttgaag aaaacaaatt
      301 cttcaggaaa accgaaacgc gacttcacta aattatcgac accccatacg tatgtcatta
      361 tttttggtgt agtcatcttt gcatggatac tgacttttgt cgttccagca ggaaagttca
      421 gcacgcaaga tattgaatac aaagatgcaa atggcgaaac aagtactcgt actgttttac
      481 gtcaagattc cttccgttat gcttacgagc tggataagtc gtatgtgttt gatcaattag
      541 aagaactgca agatcatcca gcagaacgtg aaaaactgga tgttccggaa aaaggattgg
      601 aaaaagtcat tgctgacgga gaaaaaaatc ttacgcagga aaaactagat gaaatctcct
      661 tgacagatga tgtgctttac gatcagtacg gcgaaaatat ctatgatact tctaaaaaat
      721 tgcataaaac agccaaaata tggggaacag atgattttgg cggctttggt ttcttaaatt
      781 ttgtttttga aggactagta tctggagata agtatggatc tgctgtaggg atcgctgcat
      841 tgatccttgt tgttggaggt gcttttggta ttattatgcg taccggagcg atcgacgcag
      901 gtatctatgc gtttatcagt aaaactaagg gactggagcg tttagcttta ccgctattat
      961 tctttgcttt ttcattcggt ggcgctacat tcgggatggc agaagaggta attccattct
     1021 caatggtgat ggttccattt gtcattgcgt taggatatga ctcgatcgta gcagtaaccg
     1081 tgacttatgt cgcatctcaa gtcggaaatg cgacctcttg gatgagcccg tttagcgtag
     1141 cggtggctca agggattgct ggaatccccg tgttgtctgg tgcgacattc cgattgatta
     1201 tgtgggtagt tgttactgca ttagccgctg gttatatgat gatatatgca gaaaaaatcc
     1261 gtaaaaaacc agaaagttcg ttgacttaca aatcagatga ttatttccgt tctcatatca
     1321 aaaagacatc tgatgaaaat aaaaaattca tgcttgggca taaattgatc ttattagaga
     1381 tgttagttgt ccttgtctgg atcgtttggg gcgtgactca aaaaggctat tacattccag
     1441 aaatcgcttc tcaattcttt gtgatgggat tagttgctgg aatcattgct gttcttttca
     1501 aattagatgg aatgaaagtc aatgacatcg cttcttcttt ccaatctggt gcagctgatt
     1561 tagctggtac agcaatcgta gtaggtatgg ccaaagggat tcttcttgtc ttgggaggat
     1621 ctgatgcatc tgttccttca gctttgaata cgattttgca tgggatcggg acggcgttga
     1681 ccggtgttcc agctgtcatt ggtgcttggg cgatgtacat cttccaaagt ttgttcaact
     1741 tggttgttac atcaaattca ggacaagcag ctttgactat gccaatcatg gctccactgg
     1801 cagatttagt aggtgtatcc agacaagtag cagttcttgc ttatcagctt ggttcaggtt
     1861 ttatggacgc ttttacaccc gtatcagcca gcttgattgg tgtgctaggt gttgcacgga
     1921 tcgaatgggc aaaatgggca agattccaaa tcaagatgca aggattcctg tttgttttag
     1981 gaactatttt catcatgatt gccattgcaa taggtctgca gtagtactgg agacctgtaa
     2041 ataaaaaagt aatccaaaca gtagataagg actccaagaa ccgtcatttt acggtaaaat
     2101 caaaggagta aagatcctat cgtttggatt attttttaag atcctatcat cagttatact
     2161 taaagaaaga ggaaaaatgt atgaaaatca ttcgacaaat tgaagtgttt gcaccagatt
     2221 acttaggaaa aatggatgta ctgattgccg gtgggaagat tttggctgta gaagaacagc
     2281 tagaaggcgg ctacgaagga gtggaagtag aagaactttc aggtgaggga aaagtactaa
     2341 ccccgggttt cattgactgt catttccata ttttaggtgg aggaggagaa ggcggttatc
     2401 aaaatcgaac gccagaagtc acattgagcc aattgactac agctggtgta acgacagttg
     2461 tcggttgttt gggaacagac ggagaaggta gagatatgac tgcgttgatc agcaaagcga
     2521 aaggtctgga agcagaagga atctccactt atgtatacga aggttcgtac cgattgccgg
     2581 taaaaacagt aacagattct atcatcaaag actttttgac aattgataaa attatcggaa
     2641 tcggagaaat cgcagtatcc gatcaccgtt cttctcagcc aagttttgaa gagttcgctc
     2701 gtgcagtagc agatgctcgt gtaggaggca tgttatccgg aaaagctggg atcatcaatg
     2761 tccacttagg cggaggaaaa agaaagctag agctattgac acgaatcgta gaagaaacag
     2821 aaattccgat cacacaattt ttgcctactc atgcaaatcg cacaccagaa ttatttgaag
     2881 cttgcgtggc atttgccaaa cgtggtggca cgattgactt cactgctagc gaagatcctg
     2941 atttttggga gaagacagat ggtgaagttc gcttcagcaa agcactgaaa cgattgatcg
     3001 aggaagatgt ttctttagat aatttcacga tgacctcaga tggacaagga agcttgcctt
     3061 attttgatga aaacaatcat ttcctagggt taggagtagg aagtgccaag gcattgctag
     3121 tagggatcaa agaagctgtg caaaaagaaa gtatcccttt ggaaatcgcc ttacgagcta
     3181 taaccagtaa tccagcacgt atattgaaat tggataaaaa aggaaaaatc gaaattggtg
     3241 ctgatgcaga tctgtgtatc ttggataaag aaacgcttga tattgataca gttatcgcta
     3301 aaggagaaat aatggtccaa gaaaaagaag tcaaagtatg ggggactttc gaaaaaagtt
     3361 tttaatcaac agctctaact atctttttta gaaaacgagc gttctgtttg tctgtatctg
     3421 ttgttgatgt taccctgaag gtagatcaat aaacaaacta agaggaggaa gcacaatggc
     3481 agatttaaaa ggacgttcta aagatatgaa agataaagta gtcggtgaag gaaaagaagc
     3541 atacggcaaa gcaacagacg acaagagcaa agaaacagaa gggaaagcac aatcactagg
     3601 tgctgacatc aaagaaaaag ctcgaaattt aggcgacgaa gtcaaagaca agttttctcg
     3661 aaaagacgaa aaaaaataaa aaccacttat tactaattga atcaagcaaa taaaaaatcc
     3721 gaaccatatc tgcgagacag atatggttcg gattttttat ttgatcatta tcctgttttt
     3781 taaacttcga ttttttgaaa ttttttattt tttagttcaa agacttcatc acagcttttt
     3841 gctacttcaa tctcatgagt cacgatgata atacagcgat tttgttcatg ggcgatttct
     3901 tggaaaagtt tgacgatatc ttgtgaagtt gtttcatcta gatttccagt aggctcatcc
     3961 gctacgatta gttgatgttc acagcagata gcacgaacga tagcgactcg ctgctgctga
     4021 cctcccgaaa gtttggtcac ctgttttttt gctaatattt catcaattcc tacacgagcc
     4081 agtcgatcta aagcaacttg tcgataattc tcttgcttgg tcttagtgat ttccattgct
     4141 gctatgacgt tgtctagagc cgataaataa ggaagcaagt tgtaagcttg gaaaataatc
     4201 gagacatcat ttttacgata acttcttaac ccgattttgt tcagtgaacg atcttgatag
     4261 tatacctttc cttcttttgg tgcatctagt ccagaaataa gcgaaagaaa agtcgttttt
     4321 ccagaaccac ttgctcctaa aatagcgtac atttttccag cttcgaaatt cagttctaca
     4381 tctttataaa gcgcatcttg cggatcttga taccaaaatc ccaattgttc tgtccgtaac
     4441 atcaaattcc tcctttagtt taataggatt tttcttgggt ttaatcttaa tatccctata
     4501 gaagctaaaa agacagaaaa cagactgatt ccaaatgcta ctccggctaa tagtcccaat
     4561 tgtgcaggtt tgacattgat ttccaattcg ctgacttgat cagaaacagc aaatggatta
     4621 ttcgtggttc cttgttgacc atcgcgttga ccgccttgtt cttgtctgtt acctggcatt
     4681 tgtccaccgc caggagcttg ctggttttgt gtcgtggttt ctgtctgttg gtcaagtagc
     4741 tgctgtccca cggcattcgc gacgacgttt ccgctaagcg aagcaactcc taatgcaaga
     4801 atcatacaaa tagccacttc ggtaaacaat tggagaatga ttttacttct ggattctcct
     4861 aaagatagca agacgcctaa ctcatgccga cgctcccgaa tggtaatcat aatgatcaga
     4921 gtaagtatga taataccggc tacagtcact agtaaaacaa catttttaga aaaacttgcc
     4981 acgttgttta aaggttccaa cattgactga tacatggaat catttgattg taagctaaat
     5041 gtatctgtgt cgatcagctt ctcagcttct ttgagaaact catccatttt atctggatca
     5101 gatagagtgt aaatagcaga atctatcgtg ttatcgtcag atgtcccatt tagttcattt
     5161 gcaaaagtgt aagaagtgta aagtgtattc gacggattca tgaagttgaa tttcataccc
     5221 atactgccgc ttgtttcgct ggattcataa attcctttga tcgtcatttc ataagtggta
     5281 tcttcatctt cagtactcgt gattgtgaaa gtatctccga ctgccaggtc atttgtttct
     5341 gctagagtag aatcaatgac tacattgttt gtgcctttgt cgctgtcatc tattccttca
     5401 ccatccgtga tttttgctgt tccatcagaa aaattactat tttgtgcagt tgctgacaca
     5461 ccactgattt gaaagtctgc ttgagtcatt tgcggattcc cgcccattcc tccagcaggt
     5521 tcaccgcctg catcagtagt ttctgaactg tcttcacttg aatcagaact agtgatggca
     5581 gttattccat cttttgccat agctgaggcg gaactttcaa aggaataact ctttacatta
     5641 tctaattcag ctattttttc cgcgtccgtt aaggaaactg gtgtaagaga aaaactgcct
     5701 ggatctggac gttcttcagt ggtagaaccg cttgaagaag tttgttcctg ttttttaaat
     5761 gaagcttctc gattggcact taaagtcact gttgctccaa cttctttttg tgcttgattc
     5821 gctgcttctt ctgcagcgct tcgaatcgtg aggccagcta gcacaaaaat aagaatggct
     5881 gtgaacacgg caaacaataa caatgaacgt ccccatttta cttttgtact tttccatgca
     5941 cgtttcataa aattcatatt ttgcatccct cctagtagat gcatttgata atagacaacc
     6001 tatcttaaag ctagcttaaa tcttatgctg tttgcacacc atcaacatga ggttctgtat
     6061 atataaaaag tcactatagt tattgcaaaa aatgtggtaa aatgaaaaaa gtatgtttca
     6121 aaccgacgaa gaagaaatga aagaggaata gcaaaagaaa tcctagatgc tacagaggga
     6181 tttttacgtg catagttgtt ctaacaattg ctgatactag cgatttagtt tatttgttgt
     6241 ataataatgg ggaacagctg aatacttata taagtattct ggctatagcg tttcgcaaaa
     6301 gatccatttt gttaatgaag tatatccaaa ataaaatgcc catccaactg tcagaacgcg
     6361 gatgtgctgg taattttcct gctgattctc cataagttga gaaatagtga ttttgcatat
     6421 gcttcattgg aatggctcat atatttagat aaagaagaaa atcgacatct ttaaacttgg
     6481 atgtcataag aagaggtgaa gtttgtgagt accattaaaa ttatcccatt aggcggcgtt
     6541 cgtgaaaatg gaaaaaacat gtatgtcgca gaagtgggcg aggatatttt tattttagat
     6601 tgtgggctaa aatatcctga aaatgagttg ttggggatcg acgtcgtaat ccctgatttt
     6661 acgtatttag aagaaaacat tgatcgtgta gctggtgtct ttttaacaca tggacatgca
     6721 gatgcgatcg gggcacttcc ttacttgttg tcaaaaattt ctgtaccagt attcgggaca
     6781 gagttgacga tcgagttagc aaaattgaat gtcagtcgta atgaagcagc caaaggattt
     6841 aaggatttcc atgtggtaga tgagcataca gaaatagact ttggtgaaac agtagtgagc
     6901 tttttccgta ccactcatac gataccagat tcagtgggga tcaatctgaa aacaaaagaa
     6961 ggtagtatcg tttatacggg agattttaaa tttgaccaaa cggctatccc aatgtatcaa
     7021 acagattatg cacgattggc ggaaatcggc aaagaaggag tcttagcctt actaagtgaa
     7081 tcggcaaatg cagaaaatcc tcagcctgta gcttctgaag cccaaatagc agatgaagta
     7141 tttgatacga tcaaatattg ggaagggcgt atcatcgtcg cttgtgtagc aagtaatttg
     7201 caacgagtgc aacaagtatt ggatgcagca gaaaaagcac aacgaaaagt tgtcttgact
     7261 ggtcaagatt tcgaacgaat tattcgcaca gcgatgcgtt tagaaaaact tcaattacca
     7321 agtgaagatc tgcttgttac gttgaaagac atgaaaaact atgatccaga agaactgatc
     7381 attttagaaa ctggccgaat gggtgaaccc atcaagtctc tgcaaaaaat ggcaaacggt
     7441 acacaccgta atgtcaagat tgaagaagga gatttggttt atatcactac tacgccaagc
     7501 atcgcgatgg aaaccatcgt ggcgaaaacg gaagatatca tttatcgagc tggtggaaca
     7561 gtgaagttga tctctgagaa tatgcgcgtt tctggccatg ccaatcctaa tgacttgcaa
     7621 ttaatgatca atttgatgaa accaacatat tttgtgccag ttcaaggaga gtatcgtgaa
     7681 ttagctgctc atgcagattt ggctcatgca gtagggatgc catacaaaaa tatctatatt
     7741 actggacgcg gagacgtgct ggaatataag aacaagcgta tgagtgttgc aggaactaca
     7801 agtgcagaaa atgtaatgat tgatggatta ggcataggtg atatcggaaa cattgtttta
     7861 cgtgatcgaa aaatcttgtc agaagacggg attttcgtag cggttgtcac tatcagtcgg
     7921 cgagaaaaga aaatcatttc aaaacctcaa attacttcac ggggattcgt ttacgtaaaa
     7981 gctagccgtg atctgatgaa agaaagcagc aatatgattg aaacaatcgt tgagaaacat
     8041 ttagaaagca atgattttga gtggagcaaa ttaaagcaag acatccgaga tcaattaggc
     8101 cgttacttat ttgaacaaac aaaacgccgc ccagtgatct tgccagtcat tatggaagct
     8161 actcaacgtc gaaataaaaa ataaacaaaa agagtaagat gaacctctct atagagtgct
     8221 cgtcttgctc tttttttgcg aaaaacaaat aatttttgaa tacagcatcc ctcgctttat
     8281 aataaacgat agaataaagg gagtgaatca atgatgagtc aaacaaaagt cgaacgttat
     8341 ttagaagaac aaaagatcag ctatcaacca cttgatttta gtcatgtggt agaagaatct
     8401 ttcacagaag aactacaaaa aagagggatt gatccagctt tgatatgtaa aactctcgta
     8461 gtgaaaggaa acaaaactgg ggtgatcatc gcattgattc ctttgaacga tcacttagat
     8521 tacaaaaaaa cgagacaagt gacgaaagat cgtaaagttg gttttcctgg aatggatttt
     8581 gtattaatgc atacaggata tccccacgga gcaaacaccc ctattggaat aaaactcgca
     8641 catcctgatt attgtttttt agcagacagt tctttaaaag aaaaagaaga agtaattgtg
     8701 tcaagcggtg aaatcgggag aagccttcgg ataaaagtag ccgatttaga aaagatcgtc
     8761 catcctattt acgctgattt aattagttaa gggacgagaa gagaagctaa gcagagcaga
     8821 gacctcaaac ttgagattat atctgcttgg tacttggtgc atcctgtatt atctgttaca
     8881 attgctttgt acatactgta ctatcaatcc aatgaaaata tatttagcag ctatattttt
     8941 tcattgatgt gcaagtgatg aaatcgtttt taataaaaaa gatacagaga aaacgcgagg
     9001 tgtaaaatat gaaaattacg tatcatggac attcctgttt aacaattgaa atggaaaatg
     9061 gccaacgcgt gatgattgac ccgtttatta caggaaatcc attgacagac ttaactgcag
     9121 aagaagtaaa gacagattgg ttgctgatta ctcatggtca tagtgaccac ataggagata
     9181 tgattcctat tgcaaaagaa aatcaagcca caattatcag tattgttgag attgctgatt
     9241 atgcgaacag cagaggagta gattcattcg gtatgaatat cggtggaaaa catgcgtttc
     9301 cattcggcgt ggtaaaattc gtacatgcac agcatagttc aagctatgaa gtagacggta
     9361 tcgttcagta tatgggcgag cctagcggaa ttattattca agcagaagga aaaacgattt
     9421 atcatgcagg ggatactgct tatttcagtg atctaggatt gcttgcagaa gaattcgata
     9481 ttgatgtcgc tttcttgccg attggcgata actatacgat ggggccagaa gatgcagcaa
     9541 aggctgcgca aacaattcgt gccaagaaag tagttccaat ccattacaat actttccctg
     9601 tcattgaaca agatcccgaa tcttttgtag agttactgga agatagtgaa ggaaaaataa
     9661 tgagcgtctc ggaaacgctg gaagtgtagg cagaaaatgg cgacaaaaca tgatttgatt
     9721 ttagaatata ttgaaagttt acctgttggc aatcgaattt ctgtaagaag catcgcaaaa
     9781 gaattgaatg tcagtgaagg aacagcgtac cgtgcaatca aagatgcaga aaatgtcgga
     9841 ctagtttcaa caattcaacg agtagggacc atccgtatcg aacgcaaatt aaaaaaacat
     9901 attgaacgtt tgacatttgg cgaggtcgtc aggatcattg aaggggacgt tttaggcggg
     9961 gcggcaggat tagacaaggt cttgaataaa ttcgtcatcg gcgcgatgac taaacatgcc
    10021 atggaacgct atattacgcc aggatcacta atgatcgtcg gcaaccgggc ggaagtccaa
    10081 aaattagcat tggaagatgg cgccgcagta ttgatcacag gaggattcaa tacgactgct
    10141 gagattgcaa agctagctga tgatcttgaa atgccgatct tacgcacctc ttatgataca
    10201 tttacagtcg caaccatgat caaccgagcg ttaagcgacc aattgatcaa aaaagatatc
    10261 atgcttgtca gtgatatcta tatgccagct gaaaagactc attatttgca gcagacagat
    10321 acgatttctg attatcagcg tttgtcagaa gaaacgcagc attcgcgttt tccagtcgtc
    10381 aaccgccatc atcgtttgat ggggattgtt acggcaaaag atgttttagg gaaatcgcca
    10441 aaccagatca tcgatcgggt gatgacgaaa gaaccaatca gtgtaaagaa aacaatgagt
    10501 attgcctctg ttagccatca aatgatctgg gatgggctag aagtcatgcc ggtcgtttcc
    10561 gatgacttga cattggaagg cttgattacc cggcaagatg taatgaaagc gatgcagctt
    10621 gtccagcgac aaccgcagat tgcagatacg atttcggatc agatatctgg aaatatccat
    10681 acgattgata ctgaccgtga aggaaatcgt ttggaaaacc ctaagttcaa attcgtagta
    10741 gcaccacaaa tggtcaatgg cgttggaacc atttcttttg gcgtacttag cgaaatcatt
    10801 tctgatgtcg cacaaaaaac aatggtgatg aaccaaaaac gaaatatctt gattgaacaa
    10861 gtgaacctac attatttgcg gctgatccaa ttggaaagcg aattagacat tcgtccacgt
    10921 gtattggaaa tcggcagacg ttccgctaaa ctggatatcg aagtgtttat tgaaaacacc
    10981 atcgtttcca aagcaatcgt tgtttgtcaa gtaatggaac gttcttagaa agcaggagtg
    11041 aaatgacagt acagcaagaa atagtagata caataaaaaa atacgataaa atcattatcc
    11101 acaggcattt gcgccctgat cctgatgcat taggatcaca agtaggatta gccgaactat
    11161 tacgggaaag tttcccagaa aaagaaatac gtcaagtagg tgaaacgatt gaagggcttc
    11221 gctttttagc agaaatgcaa gaagttgaag atgtcttcta ccaaggagcg ctagtcatcg
    11281 tgactgatac agctaattca cccagaatca gtgatcaaag atatcagttg gcagaaaaac
    11341 tgatcaaaat cgaccatcat cccaatgatg acccttatgg agatcttgtg tgggtaaata
    11401 caaaagcaag tagctgtagt gagatgattg cagaatttgc tttgatgttt cctgaatctt
    11461 taaagatgaa cgttaaggct gcacggttac tttatgcagg aatcgtcgga gatacagggc
    11521 gctttttgta tccctccacg acgtcccgta cattagagat tgcttcgata ttgagaaatt
    11581 atccatttga tgcaagtgct ttgaacagag agattgaaca aatgccgatg aaagtcgcta
    11641 aactttccgg ttatctttat caaaatatcc aggtggatga aaatggtgca ggaagaataa
    11701 tccttccgca agaaattctt gataaatatg gaatcgatga ttcagagaca gcttcgatcg
    11761 tttcacttcc tggagtgatt gacgaagtgc tggcttgggg gatttttgtt cagcagcctt
    11821 cagggtatta ccgcgtacgt ttacgttcta aggggccgat catcaatgaa ttggctaaac
    11881 gccatcatgg aggaggccat ccattagcaa gtggtgcgaa tgcaaaagat ttagcagaag
    11941 tagaggaaat ctataaagag atccaagata tatgccaatc gtataagagc agaaaaacag
    12001 aatgatactt cgttcgaaaa cgtgcctttt gtagtaaaaa tcacaaatgt atcttttcaa
    12061 gatcttcttt ttccgttaca atagtgctca ctaaagattt taaaggagaa agaagatgac
    12121 attaccaaat tgcccagaat gtggctcaga gtacacatat gaagatcgag gcttgttgat
    12181 ttgcccagaa tgcgggaacg aatggaacaa agaagaacaa gaaactgtca tagaagacgg
    12241 attagtggta ttagatgcaa atggaaaccg tctgttagag ggcgatagcg tgacagtgat
    12301 taaagacttg aaagtaaaag gtgcgtcagg tgccattaaa caaggaacaa aagtcaagaa
    12361 catccgttta gtagaaggcg atcataatat cgattgcaag gtagaaggat ttggaccgat
    12421 gaaactgaaa tcggaatttg tgaaaaagaa ttaaagaata ttcaaggtct tttcacattc
    12481 ttttcctact actaatgata aaataaagta aacgaaaagg agtgaaacga aaatgtatgg
    12541 ttatggaatg tatggttttt tagatccgac atttcttttg gtcattcttg gattagttat
    12601 ttccggaatt gcgtcagcgt acgtcaatag tactttccga aaatacgatc aagtgagaag
    12661 caaaaacaat gtgactggta cacaagcagc acaatatata ttacaaagtc aacagataaa
    12721 taatgtcggt gttcaacaaa ttgccggaga tctcacagat aactacaatt caggtaataa
    12781 gatgttgagt ttgtctcaag caactgcaca gtctacttca gttgctgcga taggtgtagc
    12841 agctcatgaa tgcggacatg cggtacaaga tgcttcgggt tatgtcccat tgaagattcg
    12901 tgcagcactt gttccagcag ctaactttgg ttcgatgatt tcgttcccct tgattatggt
    12961 aggtgtattg cttagctgga actctacgtt aatcaatatc gggattttcg ctttttcttt
    13021 agcattactt ttccaattgg tgacattacc agtcgaattt aacgcgtctc ggcgagcaat
    13081 ccaaattttg agtgaaggcg gactactgac ggaagaagaa gtaccgatgg caagacacgt
    13141 attatttgca gcagcactga cttatgttgc agcagcgctt tcgacattcc tgcagctgtt
    13201 gcgcttgatc ttattgttcg gcggcaaccg aagagattaa aataaagaag ttgtgaaatc
    13261 agcgctttga tctgagctaa taccgagagt tagctgattg aataccattt atttggaata
    13321 agggctcttt gtcaataagg actgatgggt tgtacaaaat caaatctggg tcagaatgaa
    13381 cctcattctg gctcagattt tttgttatct tactttgatt aattgattga tcaaaaagat
    13441 tctaattctc atgttctcaa atgatttaaa tccgtaggat actcgtttca ttgtctttat
    13501 atgggtattc ttcgcttcta tttttccatt ggtgtaagga tagatcatcg cgttggtgat
    13561 gccttcttca taggtcagaa ggttttggag cttttcccga aagccgtcat ctaacgtttc
    13621 gggaagttct gccaataagg agaaaaataa gtcagggtct ttgtctcgaa aggcttcaac
    13681 taattcatga aaatagggat acgcctcctt cagggacgta gaaaagccaa gcaatcgatc
    13741 aatcatcatc gcttccgtaa gaaatgggta ttttggtgct cgaaaacttt tccatgtttt
    13801 gtattcataa tggttgatgt ttgcacgatt ttttagcaaa aagcgccagt tctttttcag
    13861 tttttctgcc tgacttttct gtcctacttt acgaagttca ttcatttcac ggatacgcaa
    13921 ctcattaaag gcttgattca tgtgtttgat aatatgaaac cgatcaatca ctactttcgc
    13981 atttggcaga atacgtttgg taagctggaa gtaggcggcg ttcatgtctg tgactaaaaa
    14041 ttttacttct tcaggattag cgcagcctaa gaaatagctt gttaatcgag gcaatttacg
    14101 cgtaggcaag acatcaatta attgtcctgt ttcgccatct gcgcaaataa agctcatttt
    14161 atcttctatg gaagcgtgcg aacgaaattc atcaaccatc aatactctgg ggagaatcct
    14221 cttagattgc tttggtaagt agcttttaaa ctctttcaac gtacgaataa cggtggtcaa
    14281 agatacctga caatttttcg caataaaaga taaagatact ttttcagtca gtaaagaagc
    14341 aattttatat ctgacatgat tcgcgattga atgtctgggt tgaacaaaat aactttgagc
    14401 cgtccaatgg gttcgacagt ttttacaggt atagcgctgc ttttttaagc gcataaccaa
    14461 aggcatgtga ttgtattgtt caaagcggac aatcgtttcc ttcttcccat ttttcactac
    14521 aattactttc ccgtttccat ctaccacagt agaaccacaa tttctacagg tatggggagc
    14581 aggtgagaaa acagcatcga cgatcaacgt ctttttcttc tgaaaggtct cgtaagagac
    14641 ctctgtaatc atcaaatctt tctctattaa tcgcagcatt tttttgatag aatcattcat
    14701 atagcatatc gtcctctcag ttgtttattt tgtcgtgatt taatcatact agagaacgat
    14761 atgtttttta atacctaaaa t
//
LOCUS       DAFKHN010000060        14591 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFKHN010000060 DAFKHN010000000
VERSION     DAFKHN010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.060"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(18..293)
                     /locus_tag="LY912_001990"
     CDS             complement(18..293)
                     /locus_tag="LY912_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955655.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            587..1402
                     /gene="thiD"
                     /locus_tag="LY912_001991"
     CDS             587..1402
                     /gene="thiD"
                     /locus_tag="LY912_001991"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBM6955656.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1607..3058)
                     /gene="cls"
                     /locus_tag="LY912_001992"
     CDS             complement(1607..3058)
                     /gene="cls"
                     /locus_tag="LY912_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBM6955657.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3400..6066
                     /locus_tag="LY912_001993"
     CDS             3400..6066
                     /locus_tag="LY912_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBM6955658.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6430..7182
                     /locus_tag="LY912_001994"
     CDS             6430..7182
                     /locus_tag="LY912_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBM6955659.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7204..8358)
                     /locus_tag="LY912_001995"
     CDS             complement(7204..8358)
                     /locus_tag="LY912_001995"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBM6955660.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8543..10984
                     /locus_tag="LY912_001996"
     CDS             8543..10984
                     /locus_tag="LY912_001996"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBM6955661.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11314..12018)
                     /locus_tag="LY912_001997"
     CDS             complement(11314..12018)
                     /locus_tag="LY912_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955662.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(12205..12450)
                     /locus_tag="LY912_001998"
     CDS             complement(12205..12450)
                     /locus_tag="LY912_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955663.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12467..13318)
                     /locus_tag="LY912_001999"
     CDS             complement(12467..13318)
                     /locus_tag="LY912_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBM6955664.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13484..14488
                     /locus_tag="LY912_002000"
     CDS             13484..14488
                     /locus_tag="LY912_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBM6955665.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         4689 a         2557 c         3033 g         4312 t
ORIGIN      
        1 taaagaacag ttagaagtta aaattgctga ttcacataga gtttatgact tcttggaaat
       61 tctttttcaa tcagtttttt catctgttta tgaaattctt ttttttcagt aaacataaag
      121 gtttgggtat cgtaaccttc ttcatgtagg aaatagatta ttcctttttc tgtgttttgc
      181 gtataagctt ttatactcct gtcttttttg aaagaacaga tcgtatagcc atctatttgg
      241 tctggtagtc gtttgatttt cttcaaaatg acttttttat cctcaagttt catttttttc
      301 acctgacttt atttttttca tatggaaatc atagcgcctt tggttatatg aaaacaagaa
      361 ggatactgaa atatatataa atcaaatagt ggttatttat tattagaata gcgaatacaa
      421 acaaatgaca actattttct gatttattac aaatgttttt tcaaataaat ttgattacca
      481 agaaaaggta gtggtatatt tactgaggga tactttgaaa aacatatgat agaaacagta
      541 acagcattat gaaaaatctt tttataaaaa tggaggaatc gatttgatgg aagatcagta
      601 tgtacaagca atgacgatcg caggatcaga tagcgatgga agcgcaggga tgcaagcaga
      661 tatgcataca ttctttacaa gaaatgttta cggtgtttct gtcatgaccg catgtgttgc
      721 aggtaattct tacggaatcg gagcaagtgt gacattgcca acagatttta tcgacaaaga
      781 atttgaactg attgcgaagg actttcaaat acgtgcagct aaaacaggta tgctagcaga
      841 ttcaaagttg attgagacag ttgtaaaaaa ttaccaaaaa tatgattttg gaccattagt
      901 cgtggatccc gtaatcgtaa cgaaacatgg aaatctttta ctagaagaat ctgctttgca
      961 aagcttgaaa gaaaagcttg tccctttggc cgaagtactg acacctaatt tttatgaagc
     1021 agaaaagctg actggacgga cattagcagc tgaagaagat tttgtgcaag cagcaaaaga
     1081 actgcaagat atgggtgcaa aaaacgttat gatcaaagga catcatgcta aagatgcgca
     1141 gcaagaaaca gtcaatgact acgtattgct cgaatcagga aaatcatttt ggttaaatgc
     1201 accattttat cctaccgacc ggatcaacgg aactggcgat tcgctatctg catgtattgc
     1261 agctgagtta gcgaaaggaa aaacagttga acaagcgatc cgattggcaa aagactatgt
     1321 aaaccgtgca attcgtgaag aaataaatgt agggcacaaa tatggaccca tcaatcattg
     1381 ggcagctggt gaattagagt aaaagaaaga ggtcgtgagc ctgccgtcca gctccgagtc
     1441 acaaggaaca agttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg
     1501 aggagttggc aggagaacac cgtttgttcg gaagaaggga ctgtgacaag atttttgtca
     1561 cagtcccttt aatcttagta tatttttctc tacttgaata aaaaaattat aggattggag
     1621 aaaataatcg agaaatttgt tgcttgaata atagccagtt agacatttcc ttgactgttt
     1681 cagttgtcat ggatgaacaa tgtgtctcat cttctttgaa ctgagtagca agttcttcta
     1741 aaaactcagg atcgtaaatg acagcacttg tttcaaaatt caatcggtag ctacgaatat
     1801 cttgatttgc tgaacctacc atgcagattt catcatccat tatcaatgtt tttgcatgga
     1861 ggaagccgtt ctcatagaca aggatttgta cattttcctt gatcagctgc cgagcataat
     1921 attgtgttgc tcgataaata aaaggatgat ccggtttgtt gggaatcatg attttcacat
     1981 ctacaccaga ggcagttgcg atttttaaag cagcaatgac actttcatca ggaacaaggt
     2041 aaggtgtctg tatccaaaca cgttttttag cagaagtaat caatttgata aatgaaagct
     2101 tgatttgttc cctttcgtta ttcggtccgc ttgaaacaag ctggatggat gtatcagcaa
     2161 gcttagattc atctcgatct gcttttttaa agaaataatt caaatgatag ccgacctttt
     2221 tttcttcagg taccgagacg ttccagtctg ttaagaagcg aagctggagc aaagaagaag
     2281 cggcaccgaa aatccgtata tgcgtatcgc gccaatagcc gaattttttt gttgtattta
     2341 catattgatt ggcaatattg aaaccaccgg tataactaat ctttccatcg atcacaacga
     2401 tttttcggtg atcatggtaa ttcaatcgga aacgaagtaa tgccttttgt gaggtaacaa
     2461 atgtatggac atgtccacca tttttgatta gacgattgaa atcttttgct tttgtaccat
     2521 gagagccaaa tgcatcatat aatattcgaa cttccacgcc ttctgcggct ttttcttcta
     2581 aaacatgtaa gacttgctgg ccgatattat ctgtcacaaa tgcgtaatat tcgatatgga
     2641 tcgaatgttt ggcttttttt agatcttgaa gcagtgaatc caatttctct tgtccgtctg
     2701 tgagaagagt gacagaattc attcttgtca gcggcatacg atttaatgaa gagaagaagt
     2761 cgacaaattg ctgtttgtct ttatcgccca tgtcaggatc gtaatgttca atggtatctc
     2821 ctctaaaaga ctgaaagttt tctaattctt tcaagtcact ttgtcggaga tagaattttt
     2881 tcttatccgt taatccacgt ccgaaaaata aatataatac aaagcccacc ccaggaaggg
     2941 caaacaatac taagagccat gcccaaatgg ctgctacatc tcggggtttg atcaaaatag
     3001 ccaccaaagc aataagtgca tttaatagat aaagggcggt tataatacta gataccacaa
     3061 aaatgttcct ccttacatac aataacatta gtatagcatg atagaagaaa gaagcctacc
     3121 aaggtgaata tacttttcac tcctttcatg aaaatgtagg taaatcgggc taaagtagtt
     3181 gctttttgta ggttaataag gtaggatatt agtacagttg aatatctcct taggggagta
     3241 accggcaacg tttgttgcga taatatcaac agtaagttaa ccaaatggtt ttctggtatt
     3301 gtatgaaatg gtgagaccta agacaaatgc gtatttgtct taggtctctt tttttttcag
     3361 acaggactag ggccaagatc aaaaaatggg ggatgaaatt tggaaaacaa ggaacaagca
     3421 caacaagcgg tctataaaga aacgatcgac tcgttgatgc agcaaacgca gagctcaacc
     3481 gatggattga gcaccacgca agcgaaggaa aaattagaaa gagatggctt gaaccagcta
     3541 aaagaaaagc cgaagaagcc aacttggaaa ttgttcttag aaactttcaa agatgcaatg
     3601 gttatcgtat tgctgattgt cgcactgatt cagatggtca tgggtgacta catcgaattc
     3661 ttagttattt ttgcagtatt gatgttgaat tctataatca gtgttgtcca aacaaaaaaa
     3721 gcagaaggtt ctttagaagc gttgaaaaac ctttcagcgc ccgatgctcg agtgattcgt
     3781 gatggtaagg aaaaaacgat tccggcaaac gaacttgtgg taggagatat cgtgttgtta
     3841 gacgcaggcg attatgtacc tgctgatgga cgtttactag atgcgggatc attaaaagta
     3901 gatgaaggta tgctgacagg agagtcgact tctgcagaaa aagaagtaac ggatatcaca
     3961 agtacggtac caatcggaga tcgtacaaat atggtattca gtggaacgat cgtaacttac
     4021 ggacgcggta aattcttagt gacttcaact gggaataata cggagatcgg acaagttgct
     4081 ggccttttgg aatcaacaac tgagcaagtc actccgttac aacgaggtct ggataaattc
     4141 agtaaaaaac taagtctggc tattttggca ttgtctttat tgattttagg tatccaactg
     4201 tttcgtattt atcttggaga aggtacagga gatatgactg cagatatcgt cagcgcagtg
     4261 atgtttgccg tagccgtagc cgtagctgct attccagaag cattacagtc tatcgtaaca
     4321 atcgtgttat ctttgggaac gaataaaatg gcaaaacgtc atgccattat tcggaagctt
     4381 ccagcagttg aaacacttgg ttcgacaagt atcatctgta cagataagac tggtacattg
     4441 acacaaaaca aaatgacagt tgttgactac tttttaggta atggcgatac tggggatttc
     4501 acaaatgacc cttcaaaatg gacagctgac gaacgtcgct tgatcgaaat cagtgtttta
     4561 gcgaatgatg catcgatcag tgaagacggt actaaattgg gcgaccctac ggaagtagcg
     4621 tttatcgact ttagtgaaaa attaaaccag ccttatcagg aaatccgaaa caactaccca
     4681 agacaagcag aacttccttt cgattctgat cgaaaattaa tgtctactgg acacacgatc
     4741 gataacgaaa attacttgtt tgtcaaaggc ggaccagata tcgtcttcca acgcagtaaa
     4801 aaagtattgc taaatggtga agtcgttccg atgacggatg aattgatgaa aaaattccaa
     4861 gagcaaaatg aagctttttc aacacgcgca ttacgtgtac tagcttttgc ttaccgtcca
     4921 cttgataatt ttgatttatc atttgaagat gaagacgatt tgatccttgt tggtttgctt
     4981 gctatgatcg atcctccacg tgctgaagtg actcaggcgg taacagaagc aagaagtgca
     5041 ggaatcaaaa caatcatgat tactggtgac cacaaaacaa cagctgttgc tatcgcaaaa
     5101 caaatcggga tttttgaaga aggaaacctg gctttgaccg ggacggaact agatgaattg
     5161 acagaagatc aactaaacga agttttagaa aaagtcactg tttatgcacg tgtttcacct
     5221 gagaataaaa ttcgtatcgt tcgtgcttgg caaaataaag gtcatatctc agctatgaca
     5281 ggtgatggtg taaatgacgc accagcattg aaacaagcag acatcggaat tgctatggga
     5341 acgggtacag atgtggcaaa agatgcagca gcgatggtat tgacggatga taactttgct
     5401 tctattgtca gcgcagtaga agtaggacgt aatgtgtttg ataatatcaa gaaagctatt
     5461 tcttatctat ttgcaggaaa tttaggtgcg atcattgcga tcatctttgc cttagttgct
     5521 gactggtcca atccatttac agcattacaa ctgttgttca tcaatttagt caatgattca
     5581 ctgccagcaa ttgcattagg tacagaaaaa gctgaacctg ctacgatgaa ccgcccgcca
     5641 agagatccaa attcaggaat ctttacggac aaaacattga tttctgtaac gtatcgtggt
     5701 gtgctgattg ggattgctgt tatctttgct caatggcttg gcatgcagca ttcacctgaa
     5761 ttcggtgtag ccatgtcatt ttcaacattg atttggtgtc ggacattgca aacattccca
     5821 gcacgttcaa acacacaaac agctatccaa gcagggttct tctctaacag aagtgtctta
     5881 ctagctgtag ttgtatgtag cgcgctttac tgcttaacaa tgatcccagg actgaaagaa
     5941 gtcttctcta tcccatcagc atttggattg acagaagtct ttacatgtat gggaatcgca
     6001 cttgtgacaa ttgttttgat ggaaatcact aaattgatca ttgtacgagt acaaggaaat
     6061 aaataaaacg aatcaacgag gttgtgagcc tgccgtttaa ttctgagtca caaggtgcaa
     6121 tttcaacaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga agagttggca
     6181 ggagaacacc gtttaaggaa gaagttgtaa aatcagcatt ttgagctaat actgagggtc
     6241 atctgattgg acactgttta ttcggaaaga gggactttga cacgactttg gtcacagtcc
     6301 ctttttttat ttatgataga cggaaagcca atcattttat tattcatcaa aagagataga
     6361 atagataaaa gaggagaata atttattccg aaaagtgaaa acatataaca aaaaattaga
     6421 ggaaatcaaa tgaatgaaaa agaatgggat gaatttgctg aagaatatta tgaaatccag
     6481 caagaatcgc aagtaactat tgctgaagat gtaaaaaatt atctgaaaac ggagaaagtc
     6541 ctgcctgctg aaacagcagc agacgttgct ggaggatctg gcagatttct ttccttagca
     6601 aaagaaatta atcgctatga tttgatcgat ttttcttcag gaatgctaga aaatgcaaaa
     6661 aaagaagcag aaaaaaatga gttgccaaat gtttccttta tcaaacagtc gttagaagaa
     6721 tttatccaat caaatgagac atatgaaatg gtttttacag cagcaaatcc agcattggta
     6781 catcttattc aattagaaaa attgatgaaa aagtcaagca aatggtgcgt gataatcagg
     6841 gtagtggaat caatcgatga tgttttttat cctatcgaaa agcaactagg aatgatagaa
     6901 gaagatccta atacatcgcc agttgtaatg gatcaatttg aaacatactt aattgatgaa
     6961 ggattcaaag tgaagaaaaa agattttact tattttacac aggaatcaat tactgaagaa
     7021 ttgatgaagc tatactatga cgcgtacgca aaagatcctg ttgtgaccag gtacattcgc
     7081 aaactattca gtgaaaaacg agaaatcctt agtacgacta agctgaccta tagactgctc
     7141 ctttggtccg cagataaaaa aagaaccttt cacgactcgt gaagggttct ttttatgatt
     7201 ttattatatt ttgtagtaac gaatatcatt ttcgatcttt gtaatcgaaa aaggtacatc
     7261 tgaagtatat tctgcacatt ctccgtgttc aggaagcgtc tcactgaaaa tcgtttcata
     7321 ttcgtcaaca gtgatccgtg ttcgagaatc tagcatctct tgatgagatt gtgcgaagag
     7381 atattcttga tagttttctt ccagataacc tgtaaaaaat tcacttactg caccagaacc
     7441 gtagctgaat agaccgatgc gatctcctgg ctgtagtgat ttcgaatttt ccagtagaga
     7501 agttagcccc aggtataatg aaccagtgta aagattaccg attcgtcggc tgtaacggat
     7561 gctttcttca tagcgagcca taagacgttc ctgattttct tcgtctgttt ggtctaatac
     7621 gctttgcaat gccttttttc ccatcttagt atacggaata tggaaagcaa tcgcctgata
     7681 atcttcgagt cctcgacccg acaattcttt atgtcgattc caaacttttt ggaatgattc
     7741 gatatacgta gaattagata aaggaccatc aacaacagga aattcgctat aatctggacg
     7801 ccagaaatca tagatatctt ctgtcagaaa tacgctgtcg tcttcaatcg ataaaatacg
     7861 cgggttttga gtgatcatca tcgcaacagc accgacacct tgcgtcactt caccaccgct
     7921 tgccaagccg taacgagcaa tatcacttgc tatgactagt acttttcgtt ctggatgatt
     7981 tttgacatat tctttcgcca tgtgcaaagc tgcggtgcca ccgtagcaag cctcttttac
     8041 ttcaaaagaa cgagcaaaag attggatttt cagtaaatgg tggataatta ccgcactcgc
     8101 ttttgaatga tcaatcccgg attctgttcc gacgatgacc atgtcgatta gctcacggtc
     8161 tttttctgtt acgattttgc tggcagcatt tgctcctagt gtaatgatgt cttcatttgc
     8221 acgattgact gccatttggt cttgaccaat ccctatatgg tattttgcag gatcatcccc
     8281 acggctttct gccaactctg tcatatctaa atataaatta ggaataaaaa aggaaagacg
     8341 atcaatccct attttcattt caacacctct ttacttatga taaaaaactt actttactaa
     8401 ggtatcataa aaagattaaa agaaatataa aaaagagaat atttaaggat tgttaaaatt
     8461 taatcttaga aaaaaacaac tggaacaaga gctatttgtt tttacagcaa agaatggtat
     8521 atttttgtag gaggtggctt acttgaaaga agtcgttatg atagatgctg caagaacgcc
     8581 gataggaaag tatcgcggaa gtttaagtcc atttactgca gttgaattag gcacacttgt
     8641 gactaaagga ttattagata aaacaaaact gaaaaaagat aaaatcgatc aagtaatatt
     8701 cggaaatgtc ctgcaagctg gtaatggtca aaatgttgcc agacagattg ctttgaacag
     8761 cggtctccct gtagatgtcc cagcaatgac gatcaatgaa gtttgcggat ctggtatgaa
     8821 agcagtgatc ttagcacgcc agctgatcca attaggtgaa gcagaacttg tgatagccgg
     8881 cggaacagag agtatgtctc aagcacctat gctgaaaccg tatcagtcag aaacaaatga
     8941 atatggtgaa ccaatttcca gtatggtcaa cgacggattg actgacgcat tttcaaatgc
     9001 acatatggga ttaaccgcag agaaggttgc aacacaattt tctgtgagca gagaagaaca
     9061 ggatcgctat gccttgtcgt cccagttgaa agcagcacat gctgtcgaag ccggtgtatt
     9121 ttctgaggag atcatcccag tcaagatttc tgatgaagac gtgttatctg aggatgaagc
     9181 agttcgtgga aatagtacat tggaaaaact gggcacgtta cgtacagtat tctcagaaga
     9241 aggaactgta acagcaggaa atgcttcgcc attgaatgac ggtgcctctg tggtgatcct
     9301 tgcatccaaa gaatacgcag aaaataataa tctgccttat ttagcaacca tcaaagaagt
     9361 agcggaggtc ggtattgacc caagtatcat gggaatcgct ccaatcaaag ccattcaaaa
     9421 attgacagat agatcaggaa tgaatttatc aacaatcgat ctttttgaga tcaatgaagc
     9481 atttgcagct tcttctatcg tagttagcca agaactgcag ttagatgaag aaaaggtcaa
     9541 tatatatgga ggagcaatcg cattaggcca tccaattggt gcaagcggtg cacgtatctt
     9601 gactacatta gcttacggat tgcttcgtga acagaagaga tacggtattg cttcattatg
     9661 tattggtgga ggtttaggct tggcagtctt gttagaagcg aatatggagc aaacacataa
     9721 ggatgtgcaa aaaaaaaagt tttatcagct tacgccatct gaacggcgca gtcaattaat
     9781 agaaaaaaat gtattgacac aagaaactgc gttgattttt caggaacaaa cactttctga
     9841 agagctctcc gatcacatga tcgaaaacca agtgagtgaa gtggaaatcc caatgggcat
     9901 cgcgcagaat tttcaaatca atggtaagaa aaaatggatt ccgatggcaa cagaggaacc
     9961 atctgtcatt gcagctgcaa gtaatggtgc aaaaatctgt ggaaatatct gcgcagaaac
    10021 acctcagcgg ctgatgcgag ggcaaatcgt tctatcagga aaatcggagt atcaagcagt
    10081 gatcaatgca gttaatcatc gaaaagaaga gctgattctt tgtgcaaatg aaagttatcc
    10141 ttcaatcgtg aaacgcgggg gcggtgttca agatatctct actcgggaat tcatggggag
    10201 tttccatgca tacttatcta ttgatttttt agtggatgta aaagatgcaa tgggcgctaa
    10261 catgatcaac tcgattcttg agagtgtggc aaacaagtta cgggagtggt tccctgaaga
    10321 agagattcta ttcagtattt taagtaattt tgctacagaa tcattggctt ctgcctgttg
    10381 tgaaatccca ttcgaacgct tagggagaaa caaagaaatc ggtgaacaaa ttgccaaaaa
    10441 aatccaacag gcaggggaat atgcgaagct tgacccttac cgtgcagcaa cgcacaacaa
    10501 agggatcatg aatggtatag aagctgtagt ggcagctaca ggaaatgata cacgtgcggt
    10561 tagcgcttcg attcacgcct acgcggcaag aaatggatta taccaaggat taacagactg
    10621 gcagatcaaa ggggataaac tagttggaaa actaacggtg cctttggctg ttgccacagt
    10681 aggcggagct tccaatatcc tgccaaaagc aaaagcatct ttagctatgt tagatattga
    10741 ttcagccaag gaactagcac aagtaattgc tgcagtaggg ttagctcaaa acctggctgc
    10801 tttgcgtgca ttagttacag aaggaatcca aaaaggccac atgggacttc aagctcgttc
    10861 attagcgatc tcaattgggg ctattggtga ggaaatcgag caagttgcga aaaaattacg
    10921 tgaagcagaa aagatgaacc agcagacagc tatacaaata ttggaaaaaa tccgggaaaa
    10981 ataaaaaagc aatatcttta gaagaataaa gcaagattta cagttatttt atttactgca
    11041 aatcttgctt ttttctctat cagaaaatat gtttattatt agaatttttt atagttaagg
    11101 ttaggcatct taagaaatca ggcaactcca agatatcttc aggtagaaga gaagtcgcct
    11161 aacattgtag gatcataggt gatttgttgg acaggtcaag ctgatatttg agcctgatgt
    11221 tagaaggaat ttctttttac ttgctgtaga aattattata tgactaaaaa ggctgggatt
    11281 ttaaatccca gccttttatg acaaatagaa tttttatcga tcagtaatcg ctgtcgctgc
    11341 aaattgttcg atcaaaggaa tcaaagtcaa tttgactttg tatttccgtt cgagtgcttt
    11401 ttcgataacg aactcatttt cagtagtcat agaaatagtt gctaatttac gaggttcatc
    11461 agcatttttt tcattaataa ctacttcatg ttcattttgt tctgtgtaaa atttaggata
    11521 ctcagcaacg gcttttgaaa aatcagcaaa acttaaagcg gcattcgtat cagttgagcg
    11581 tgtattttca gttgtgtccg cttttggttt ttccgttttt tcttctggca cactgactgt
    11641 ttcttctgta actggtgtcg caacagcttg cgcagttggt tcatcgtttt tcaatcgttg
    11701 atcattccag taagacacga tttcaataag aagattgtca cggaatcgtt cgaaaatccc
    11761 gttttctcct gaacgaattc tctttaatac agtattgaag ttgtcatcga ttggcacgtt
    11821 gatccgtgta tcttcatttg ttttcccagc taatccgatc gttaagattt gacggttttt
    11881 gggatcaagc atgacttgta acggcaaacc atagcgtcgc aagctctctt cttctagaga
    11941 acggaataat tgtcctctta caccatccaa tgaaggacgg aattgattta ataatttttg
    12001 tttctgtttt ttcttcatat gttctctcct tcgctcatac cctttcgatt ataagaaaaa
    12061 aacagccaaa tgaaaaggag taatgcaaaa aaacttgcgt atacgcaaat tacaacagaa
    12121 aaatttgcgt attttcccgt tttttgaaag aaaaataaaa aatggaacgg attatgtata
    12181 tatacataat ccgttccatt ctttctattt tttcggtatc aaggcaaaaa caggtagttc
    12241 aggtgaataa atgacttcat gttcgtgcca gggtttgacc attagcgaat gatcgaaccg
    12301 ttttttcagt tcttcgatga tttgatcatg tgtccagttt cttgcaggaa aatgttggat
    12361 tttctctgca tcgatcaaaa agacaaaatc ggaatgaaaa gtctgggtaa cttcttccga
    12421 gagagaattc aagcgttcga ttggatccat aaaatcacct ttcgacttaa aattgggtag
    12481 tatctgggtc ttttgctttg ccgactacac catctaactg atcgatttgt ttcatttctt
    12541 cttctgttaa ttcaaaatca aataattcag tattttcttt gattctgctt ggtgtcactg
    12601 acttaggaag aggaaggaat tcgtgttgca gcgaccaacg caaagcaact tgtgcaatcg
    12661 tcttgtcatg tgcttcagcg atttgtttca tttcaggcac atcgaagatt ttaccagtgc
    12721 ctaatggact atatgcttcg aggatcatat catgtttttt tgcatactca actacagttg
    12781 gctgtaattc gcctggtgca aggaaaactt gattgaccat cggcataatt tttgctgttt
    12841 ttgctagtgt atctagatgg tggggtaaga aattgctcac accgattgct ttgattttac
    12901 ctgcttcata cagttcttca aatgctcgcc atgtatctgc atttgcttgt tcccaattat
    12961 cacgaaaagc aacagggttt ggccagtgga tcaaaaacag atctaaataa tctgtttgga
    13021 gcttcttcaa tgattcttca aaagaagaca tcacaagttc atagctgtgg tttgcattcc
    13081 ataattttgt tgtcaagaat atctcttctc taggaattcc actttcctta atcgcttggc
    13141 cgacactttc ttcattcttg tatccttggg cagtatcgat atggcgataa cctgcagcca
    13201 gcgcttcttt aacagaggaa acagcgacat ccccatcagg tgtttgccat gtgccgaatc
    13261 ctactaccgg gatttcgtaa ccatttaata gacgataagt gcttgttaat gaattcatac
    13321 tttcagctcc ttttttattc gttcaactat aagtgtagcg catttttcga aaaaaagaat
    13381 ccattttgtt tctactcttg aaatttttgt ttaaaagaaa atgattttga ttctggtatt
    13441 tttgattttt tttccgtaaa ctaagacaga agggaatgag aaaatggata tctatttaaa
    13501 aaaagcaatt ctgcatatta ttgacagaga aactggttct ccagtctttt cacaaaaaga
    13561 gctggatctg acaaaagaat atattcgtga ttttcttcaa aagaagatcc aaaaaatctc
    13621 ttctgctcaa acaaaaactg gacaactagc agaagaaagc atgatcgttg aatcacttaa
    13681 aatcgctcaa gaaaattttg tggaagcaag tgaagcaatc gttcagcggt ggttcgatat
    13741 ctaccaagaa agtgaagaag cacctagtgc agatgtattt gttgttttgt atgaattaga
    13801 tacagtgatg tacttatctt tattgaaagt caattatcgt gaggcttaca ctcactttgt
    13861 tgaagcagac gaagcaggga tcgacaaccg cttgattttg aatcgagcaa ttctaggggc
    13921 gaaaacacaa aaagcagatg aagcattcgc tgtgaatttg actgattgga cctacgaatt
    13981 aattgaaaaa aaatatgagt tttctggcaa aaaagagctt tatttttctg gaagagtgat
    14041 cgaaagtgtt cctgcacctt ctttagaaga aaatgtaaaa gtgatccaaa aagtagccaa
    14101 gcatcttgga aaaaaatttg agacagaaga atttgatatc atggctgatt tgaaagaagc
    14161 tgtctatgat acgatagaag aaaaaggtcg gttggatcat gagatgattg cggaaaaagt
    14221 cttcaaggaa aacatcacgg caaaaatggc ttttaaagaa gaagtacaag agcaaggatt
    14281 tgtcccagaa gcacctcctg taaaagaagt acaagaaatt tctgagaaaa aatttggaaa
    14341 acaaaaattc aagctatcaa acgggatcga actgatcgta ccagtagatg tatatcgcaa
    14401 cccagatttg attgaatttg tgaataatcc ggatggtacg atatccgtga tgatcaaaaa
    14461 tgtggatgaa gtattgaatc gtttataaaa atgactagaa cattaggtgt tcaagtacca
    14521 gtgatcagtt aaatgaattg tgtcaagaga aggatcggaa aagacgaata taacaaaaaa
    14581 agagcgtgag a
//
LOCUS       DAFKHN010000061        14543 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFKHN010000061 DAFKHN010000000
VERSION     DAFKHN010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.061"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(97..729)
                     /locus_tag="LY912_002001"
                     /pseudo
     CDS             complement(97..729)
                     /locus_tag="LY912_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
     gene            complement(742..1107)
                     /locus_tag="LY912_002002"
                     /pseudo
     CDS             complement(742..1107)
                     /locus_tag="LY912_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(1173..2291)
                     /locus_tag="LY912_002003"
     CDS             complement(1173..2291)
                     /locus_tag="LY912_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6955666.1"
                     /translation="MKKAHKIRIYPNCRQEIQFQKTFGCVRFYWNFLLDQRITNYKKK
                     KENADYKEDKTTYASLKKMEEYAWLKEVEAQPLSQVAMDLNKAFKNTFNSTFGFPKFK
                     SKKYSKKSYRTAMGIKVNRNYFYVSKVGWVKMAETLRFNGKLMNVTISQSKTEKYFAT
                     FLVDIENFQKDPVTESIGLDLGLTHFCITSAGEKIGNERFYRSLEKRLVVEQRKLSRR
                     LEVAKKHNRKLEECKNYQKQRVKVARIHEKIFNQRNDFLHKLSSRITDENQIICIEDL
                     NVTGMVRNHKLAKSIADVSWSEFVRQLTYKCEWKGRTLVKIDRFYPSSQICSSCGHND
                     GKKELDIREWTCSNCGTNHDRDINASINIRTEGLSGIA"
     gene            complement(2315..2716)
                     /gene="tnpA"
                     /locus_tag="LY912_002004"
     CDS             complement(2315..2716)
                     /gene="tnpA"
                     /locus_tag="LY912_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003378761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBM6955667.1"
                     /translation="MDNEYRYSKTTVSLVNYHFVFCPRYRRKIFVNSEVDARFKALVQ
                     EIAKENEWNIIAIETDKDHCHLLINVQPTYSPSKIMKIIKGKTSSIIRQEFEHLSKMP
                     SVWTRSYFVSTAGNVSSEIIKRYVENQRTRY"
     gene            complement(3225..4874)
                     /locus_tag="LY912_002005"
     CDS             complement(3225..4874)
                     /locus_tag="LY912_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBM6955668.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVKDVEDEGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAEKANIKVTNNDGSVVLKENTDYKIENSDYKIENSDSGFVIDFIVNNGQVS
                     DTVANLHGQDLKMTYNMFVNDSAEIANPLTNSVDFVYSNNPFNQEEHHEKTKADAVTY
                     GAKFLKADGGLFGTGIKATPLEGAEFAAKNAEGKYYSFCGR"
     gene            complement(4927..5598)
                     /locus_tag="LY912_002006"
     CDS             complement(4927..5598)
                     /locus_tag="LY912_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBM6955669.1"
                     /translation="MKKWLFGFLGVALIVFCSVFGYVSYQKHEGDVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTCKFIVSEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            complement(5684..5923)
                     /locus_tag="LY912_002007"
     CDS             complement(5684..5923)
                     /locus_tag="LY912_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955670.1"
                     /translation="MNCKEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYVKKSSNCQLLLEVS"
     gene            complement(5989..6222)
                     /locus_tag="LY912_002008"
     CDS             complement(5989..6222)
                     /locus_tag="LY912_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955671.1"
                     /translation="MARPVLDAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWREHNGIKDLKPARPVIRRKKLKK"
     gene            complement(6414..6704)
                     /locus_tag="LY912_002009"
     CDS             complement(6414..6704)
                     /locus_tag="LY912_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955672.1"
                     /translation="MKFFEVKSPYYYALIAAKNEEECAELYEQVVTDIENREEFIRCL
                     HELNRNEAIQEDAKKISEETLQPIGMEEATKDIFTIIDEQKSCVLSIDSTLV"
     gene            complement(6723..7064)
                     /locus_tag="LY912_002010"
     CDS             complement(6723..7064)
                     /locus_tag="LY912_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBM6955673.1"
                     /translation="MKNYDPNSRWGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQKLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            complement(7051..7380)
                     /locus_tag="LY912_002011"
     CDS             complement(7051..7380)
                     /locus_tag="LY912_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955674.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            complement(7971..8303)
                     /locus_tag="LY912_002012"
     CDS             complement(7971..8303)
                     /locus_tag="LY912_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBM6955675.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(9139..10179)
                     /locus_tag="LY912_002013"
     CDS             complement(9139..10179)
                     /locus_tag="LY912_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBM6955676.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDSTVIAKIANTAKPRKINDST
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMQEDSINTFVPENVLNLIKTFSSSYSEAQQTVQTIHNAKKKAEELEQTIVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(10528..10854)
                     /locus_tag="LY912_002014"
     CDS             complement(10528..10854)
                     /locus_tag="LY912_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955677.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNYKPKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(10841..11644)
                     /locus_tag="LY912_002015"
     CDS             complement(10841..11644)
                     /locus_tag="LY912_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBM6955678.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTTAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(11997..12287)
                     /locus_tag="LY912_002016"
     CDS             complement(11997..12287)
                     /locus_tag="LY912_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBM6955679.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(12423..12602)
                     /locus_tag="LY912_002017"
     CDS             complement(12423..12602)
                     /locus_tag="LY912_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955680.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(12599..12949)
                     /locus_tag="LY912_002018"
     CDS             complement(12599..12949)
                     /locus_tag="LY912_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955681.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(12942..14267)
                     /locus_tag="LY912_002019"
     CDS             complement(12942..14267)
                     /locus_tag="LY912_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBM6955682.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
BASE COUNT         4180 a         2864 c         2109 g         5390 t
ORIGIN      
        1 gttaaataaa aataatatga acgcaaaaaa agcgaatagc agtgctaatc gccaatccaa
       61 tgaaattgat ttcctatttt ttgctttttt ctgtagtttt aaatcttctt tactgaatga
      121 aactcgttca ccatacacta aaaagcggtg tgagttgaca ccttttggcg tgcaggtcat
      181 taacgtaatc ctatcttggt ctttttcagg catgagataa tctaaataat tcttttgtaa
      241 ttcttctgct ttaacttctt caattcgata aatttgatag gcatgttgtt cttcatttac
      301 cttaataaag aatttttgcc ctttttttac tgaaggcaaa tcatcgaaaa gattatcttt
      361 ataaagtcca ctgtgccctg cgattaaagg atttttaccg tttcctcctg taatatcgcc
      421 agttccttcc gtaatcccta caccattctc taaaattttt tcggaagttc cgtcataaat
      481 tggtagtttt aaagaaatac ttggaattgt aagaacacca acaggatcgc ctaactctat
      541 tttcgcaaca tccaaagaag aatctgtttt ttcaagattt tcaatggcta aaattctttg
      601 cttttgttga aatttagcta catttgtttc cacaactgga attaaataga ctgctactgc
      661 cgacagcaac caaaaaaata tcatcagttt gtgcatgact cttctttttg ggggcttacg
      721 aataatcatt agctgatcct tctaggcttt cttcttaaag taaacaactg cagaaagtgc
      781 ccctgctcct agcaacaagc aagagatcaa tacatacgtt tggaaaccat tactacctgt
      841 taatggaata gctgcttttt gattattttt aacagtgatt cgattttcct ctttaaatga
      901 gtttttgttt actttaaatg caatatcttc tgttaatttt tggtaaccag ttggtgcttt
      961 tgtttcttcc aatgaatatt caccttcagt taaaccagtg atttcaaagc gcccttcttt
     1021 atctgatttt aggatcgctg catttgctac attgtctacc catactgctt ctttgacacc
     1081 gtctttatcc gtatcaacta atccaccctg acactccaca cgactaaagt catggggttc
     1141 ttaggtaata cacccaaacg ggcgcaaatt tactaagcta tccccgaaag tccttcggtt
     1201 ctaatgttta tactagcgtt gatatctctg tcatgatttg ttccgcaatt gctacaagtc
     1261 cattctctaa tatctaactc tttcttaccg tcattatgac cacaagaaga acatatttgc
     1321 gagctagggt aaaaacggtc gatttttact aacgttcgac ctttccattc acacttgtat
     1381 gttaattgcc ttacaaattc actccaagat acgtctgcta ttgatttagc taatttatga
     1441 tttctaacca tgcctgttac attcaagtcc tcaatacaaa tgatttggtt ctcatcagtt
     1501 atacgagaag acagtttgtg taaaaagtca tttcgttggt taaaaatctt ttcatggata
     1561 cgtgccactt tcactctttg cttttggtag tttttgcact cttctaattt acgattatgc
     1621 ttctttgcta cttctaagcg tcttgaaagt ttacgttgct ctaccactaa gcgtttttct
     1681 aatgatcgat agaatctctc gtttcctatc ttctcacctg cggaagttat gcagaaatga
     1741 gtaagaccca aatctaaacc aatggattcc gtcacaggat ctttttggaa gttttcaata
     1801 tcgactaaaa aagttgcaaa atatttttct gtttttgact ggctgattgt cacattcatt
     1861 aatttaccat tgaaacgcaa cgtttcagcc atttttaccc agccaacctt ggatacataa
     1921 aagtagtttc tattcacctt tatacccata gctgttcgat aggacttttt ggaatacttc
     1981 ttacttttga atttaggaaa tccaaaagta gagttgaacg tatttttaaa tgctttattt
     2041 agatccatgg ctacttggct aagtggttga gcttcaactt cttttagcca agcgtattct
     2101 tccatttttt tcaatgaagc atacgttgtc ttatcttctt tgtaatcggc attttctttt
     2161 ttcttcttgt aattcgttat tcgttgatct agtagaaagt tccaatagaa acgaacgcat
     2221 ccgaatgttt tttgaaattg aatttcttgc cgacagttgg ggtaaatcct gattttatga
     2281 gcctttttca tttctgcaca cctccttaac gcaatcaata tcttgttctt tggttctcaa
     2341 catatcgctt gataatttcg ctagatacat ttcctgcggt tgaaacaaag tatgaacgtg
     2401 tccaaacact tggcatttta cttaagtgtt caaactcttg ccggattatg ctagatgtct
     2461 taccttttat tatcttcatg attttagaag gagaatacgt aggctgaaca tttattaata
     2521 aatgacaatg atctttatct gtttctattg caatgatgtt ccactcgttt tcctttgcta
     2581 tttcttgaac gagtgcttta aatctagcat ctacttcaga attaacgaat attttccgac
     2641 gataccttgg gcaaaaaaca aagtggtaat tgactaacga tacagttgtc tttgagtatc
     2701 tgtattcgtt atccatacct taattttagg ttaagccatg tactaaatca atgttaatat
     2761 acacaaaaga atgaagaatt ttttatgtgg agtttgttca cataggttcg ctacttccta
     2821 tgcagttctc tgatgaactt ctgacacttt cgtgccagca cagactatat cttatccgtt
     2881 ggctttaccc agtacggcga aaccacttcc acacgcttgt gtgtacttcc ctcaagagga
     2941 atagtcgttg aacgttactc tgttcgagtc ttcgctgcag attgcccatt gtcgcaacac
     3001 ttaggattta accatatgct atcgagtaaa ttttttctgc tttcgccacg gtcacgtttg
     3061 cctatttcaa gactacgttg tcgttttact cgctttaggg gttccccgca attcagtttc
     3121 tttgttggga tatacgagat tttatatatt ccactaagca caagtttccc tatgctctta
     3181 cagtacagtg cgggctatca tccacacggt taaaaccgtg ggttttatcg cccgcaaaag
     3241 ctataatatt ttccttctgc gtttttagca gcaaattctg cgccttcaag cggtgttgct
     3301 ttgattcctg ttccaaatag tccgccatca gcttttaaga attttgcgcc ataagttaca
     3361 gcgtcggctt tcgttttttc atggtgttct tcctgattga atggattgtt gctatagacg
     3421 aaatccacgc tatttgttaa tggatttgcg atttcagcac tatcattcac aaacatgtta
     3481 taagtcattt ttagatcttg accatgtaaa ttcgcaactg tatcacttac ttgtccatta
     3541 tttacgataa aatcgatcac aaaaccacta tcagaatttt cgattttata gtcagaattt
     3601 tcgattttat agtcagtatt ttcttttaat acgactgaac catcattatt tgtgactttg
     3661 atatttgctt tttcagcgac ataagaaagt ccttgtcctg ctgtatcccc ccatttaaat
     3721 acactgtaag gagaagtttc gcttttcact ccgtttactg tgataccgtc tgctccgcct
     3781 gcaatgtctg ttgggatatg aatcgttcct tgataattta ctgcgtcacc aatttggaaa
     3841 gaatgttctt gtcctgttcc atttgttact gttttatcga tcactggtgc tttatagttt
     3901 acgtatgaag cttttaagtc acttgtcacg ccatcattcg taatttcaaa ggttaattta
     3961 ttgtgcgcat cgttgcgagc gtctgcgcct aataaatatt gatctgctgt tggttcttta
     4021 tctgatccca ctacaacttc tgaaggaact tccacaaaat agtattttcc taacgtcaaa
     4081 tcagtagcag tcagctttcc ttgatcatcc gatacaagat ctcctaattt tgttcctttt
     4141 ccaggttcgc ccttgtataa ctcaaatttt gcccctttta aaggtgtttg tttgctttga
     4201 gctgtgccat cgtcaccaaa tttcgttaat tcaaaactca acttagaaac aatattttta
     4261 ggatataagt gaatgtcttt taaaaaacct gaacctgtat tatcagtcat tggcgcaatc
     4321 acaaccattg gttttgcttt ttgtgtgact aatccagcag cggatttact ttcataaacc
     4381 acatatacat tccctttgga attgacatag gctggttgat cagcaaaagt gatctcacca
     4441 ttttcatcta cagctgaagt aattttattg gttgcattct taacgtactc actgttagat
     4501 ccctcgtctt ctacatcttt aacgatttcg tccactttcg cgttggttag atcagaatct
     4561 tccctcggta atacttgatc cgtaatattt cctaacgtaa actcaacatc accataatct
     4621 gccttgttgt atttcgttac acctgtagga tattgatcgt gcgtataacc atcatttttg
     4681 atcccgtcaa tatcaacatt caattgcgtt ccttgatcgt acattaattt atgaaccgtg
     4741 atattgacct tctctggtgg cgttttttgc gtgacatctt ctgcatatgc tcgatatccc
     4801 tgaaagcagc ctgcaatgat tcctaacatt ccaacaagca ttccagcttt ttttacatac
     4861 cgatttattg ccatttttta ctctcctcat ttcatatttc aacgactcgc gttgattaca
     4921 accttgttat tgtagctctc cctgtaccac gtatctttct tttccttgtg acgtataaac
     4981 acaagtaaac aacgttaata agggtttctc tcctttcttt ggtaaagaca agaaagagtt
     5041 ctcttcagga acgccatcaa ttaatttaaa gtactcagat acgataaatt tacacgttac
     5101 cttgtaacga tagacgccat cgttactaac taagtccatc acctccccta atgacaactt
     5161 ttgaatatct gaaaataaaa cacctggcat ttccatgttg tgtcctgcta gaacatagtt
     5221 tcctttgccc atttcggcat cctcataaaa ataagtagcc gctccaagac tcaaagtgta
     5281 ttgatttgcc cctttaaaaa tcggcaatgc taaaccaagt gcaggaatct gaatttgtgc
     5341 aaatacttgt ttattgacgc ccatttcgat tgcttctttt tgtatggaca acatttgccc
     5401 caaagacata tcattattga cgttcgttgc atcctcctta taactctttg cgtgtgcatt
     5461 gatttgatct acgggcatct ttttttctat attttgctta aacacatctc cttcatgttt
     5521 ttggtagcta acatagccaa acacactgca aaagacgatt aaagcgactc ctaaaaaacc
     5581 aaataaccat tttttcatcc atctgcctcc tttcagacaa aacaaaaaaa ctttttctca
     5641 tttccataga aaaagtttta aaaatgaatt ctattaatga atgtcatgag acttctaaca
     5701 atagttgaca attagaactt tttttcacat aagttcgtct caactgttca aagtttttca
     5761 ttgaacctaa caaacaagct ttctcttttc ctgttaactg catatcattg atatattgcg
     5821 cgacagataa tcttttaagg tgtttttgtt tcattgtttt tagtaacttt tcttccattt
     5881 ctttcgacac tttttttcta ttttcgattt ctttacaatt catggttttc cttcctttca
     5941 ttatttttat caaaataaaa aagcctatgt acgccatacg ctttggtctt acttcttcaa
     6001 tttttttcgt ctaataactg gacgtgctgg ttttaaatct tttattccgt tatgctctct
     6061 ccaatagtcg aattcttttc gtaatctttc tttttccata tctgttcctt tagatagggc
     6121 tttgaataca tctttaggtg aataaccacg agctaacagc tgtacatacc ttccttttgt
     6181 caaagtatcc atatccatcg catctaaaac tggtcgcgcc atctaatttt cctcctaaat
     6241 aaattcctta ctcaatgcct aaggtaatac taccttttta ttaatcgccg tgattccttc
     6301 taatccttta tctgtaaaat ctaatttgta tggttatttt cctaagtaat tggtctgaga
     6361 atcattacct aatttctttt tactttgaaa aaaattatag aatcttggat ctattaaacc
     6421 aatgtagaat caatgcttaa tacacaagat ttttgttcat caataattgt aaaaatgtct
     6481 tttgtagctt cctccatacc gattggttgt aacgtttctt cactaatttt tttcgcatcc
     6541 tcttgaattg cttcatttcg atttaactca tgcaaacatc gaataaattc ttcacgattt
     6601 tcgatatctg ttactacttg ttcatacaat tctgcacatt cttcttcatt ctttgctgcg
     6661 attaacgcat aatagtatgg tgattttact tcgaaaaatt tcataattta ttcctccagt
     6721 ttttattctt ctttatccgc tacaaattca atgatttcaa cgctgacaat ataatcactc
     6781 aaatatgacc aagtatcttc aacagataat tcgtctccat tatcattcat aagcgtcatt
     6841 ttaaaccatt cattaccttc atcatcttca ggtagcaagc cgaatccaat tggattatca
     6901 gtcaattttt gatcgtataa atcatcctcg tctaatgcta aaacatctaa tcctttacaa
     6961 tttccgcctc ttctaaacgt cacaaatcct ttgtaatccc aacgttggaa agaaacctta
     7021 atcgtatgtg ttccccatcg gctattcgga tcataatttt tcatttgttg taacctcctc
     7081 ataatcagtt agtactataa aggtatcttt gtttttatcc aaaaaatcta ataaatcttt
     7141 tgtagaagat atctcttcat caacttcacc ataataaata ccttcgataa ttgttgctat
     7201 atctgaaaaa ctaattttta ctggacattt atcgtctacc gcattcaata ccgacaaaat
     7261 tgcttctttt tctgcaatct ctcgtttgaa tttctttgga gctaatcgca tgacactcaa
     7321 gtcattttca agcttttcaa tccatgcagt tttactcatt ttcgcaaatt tttgaatcat
     7381 tcctctacca cctttgctat ctactaaatt agttttactt cataacgaat atttttatcg
     7441 tttttcgttc actcaaaaat atataaaata aatcgactcg tttatggcgt ccgaaacgag
     7501 aaaccctagt agaaaacggt aaatgctcga ttgatccaaa gatcaacgtc ttcgcaagta
     7561 tctacatgta ctgcagcaca cgacacaatt tcttgtgcgt cctccccatt acgagaagac
     7621 ctactcctta ttccatgagt ttgcgtcaaa gcctagatcc cttagtagct gctcatgatt
     7681 aatctaggcg ctattctaac ttgtctaact tctaaattcc ctcttgttta ctctgtgcat
     7741 attatttaca caaattcatt tcaccactat ccaaacaagg gcatttactc gattgaccaa
     7801 ttttttacgt taccaatcgt aaaaacctac cccgtcaccc cccgaaagga attgttgata
     7861 gatcaagtct actccttatt tttctagtga ttctaagttc ctttagaagt ctcgacaata
     7921 ttttcaagca agcgaaaaac gataaaatac aagttatgag aatgatcaat tcagctgatt
     7981 aaacgcccca tcccttttgc ggtacaacgc aagactccat tttttcttcg accaatcagt
     8041 acaccgtttt ggtcataaac atgtttgatt gttggatata gctcttttaa agggatagga
     8101 tcttttaaaa ttatttgttt ttgtttccca atgtaataaa tcatttcttc tgagactttg
     8161 tctttctgga ttatatattt cttacactgc acaacggttt tactttgacc agttgatagt
     8221 ttcttcgtga tcttttctgt agcggtacac cgtttaccgt agtgacaaat atcttcgaga
     8281 ctcaaaattc ctgtatatga cataaaataa tccacccact tactttaaat atttttaaca
     8341 agtttttctt gttatttttc aaaaatagag aattgatttt cgttcatgac aaacaaaaaa
     8401 gagggaacgc atccaaacat gcgttccctc taatttcagc gttcgtcata cggcaaagag
     8461 ccacacggac atttttataa cattatgctt aggcatagat tcatcgtaat atcacgtatt
     8521 tttaacctta acacagccaa aaaaagtggt atcacttttg aatatctgtt atactaaatc
     8581 cgttacgggt aataccgtaa cactgaaagg taaacgcatt aagggagtga tcttaatgcc
     8641 acctgtggac gtcgacgaag gttaccagcc ttccgagtct cacagggcct ttcttttttt
     8701 tgtattttca attgtccaaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac
     8761 aagcatagca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat
     8821 attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga
     8881 attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc
     8941 tatttttttg agtgaaaaat aactaaaata tctaacgatt atgaatttaa aacctacgat
     9001 tgtgattgtt ttcataaact tttaatctaa aaactccgga atactaacta tttatttgta
     9061 atatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat catttttata
     9121 gtaattgctt tttatcaact actctaacca attttccgta ctaactgttg gtaattcgtt
     9181 aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga caaaccaatt
     9241 ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt tttgtttttg
     9301 ataagctttc agtaaagtca tatataatcc tttgtcagca tcaattccat aagattccag
     9361 ttcttcataa acgacaatag tttgctctaa ttcttcagct tttttctttg cattatgaat
     9421 agtttggacg gtttgttgag cttcactgta acttgaagaa aatgttttta tcaagtttaa
     9481 tacattttct ggtacaaatg tatttatact gtcctcttgc atgatgtcga cgaagttatc
     9541 tagcaaaact tgattttgta actggtcagt ttcagtgtct attatgtgtc tattagtgtc
     9601 tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg agtccttgat
     9661 atgactggat tttgccgtat ttgcgatttt cgcaattacg gtagaatcat tgatttttcg
     9721 cggttttgcc gtatttgcga ttttcgcaat tacggtggaa tcagtattgt cttcctcttc
     9781 catgatttta aagacgtctt gattcgtaac ttctggcttg cctaagtaca ataaattagg
     9841 catagattca atcttaccat cacgtttatt tactcttcct ctcttctgtt tcagaagacc
     9901 tgctttttct aattcttttt tgatcttaga tactttacct tcgcggcatt gtaacaattt
     9961 cattaattct tcaactgtga atatgaagaa tatattatca tcagaatcta cccagttatt
    10021 tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg catcatttga
    10081 aagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat atttttcacg
    10141 ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc tttctgtagg
    10201 atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta tccactatat
    10261 atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt ttttatcttt
    10321 ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaggg tttaagctca
    10381 tggtaactat atcacgatat tacaataaca ttatatcacg atatcgtaat attacaatat
    10441 gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa tatcacgata
    10501 ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg ctagtttata
    10561 tccttcaatc aagtattctt caggtatgga ttttaatagc gcatcttcta taacgtctgg
    10621 tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca ttagaattgg
    10681 atttatacga atgctatctg ctgttcttac actacttcct tgatctttta tgactttact
    10741 tatatttttc ttggttaatt cgatttcttc tacttctttt ggtttgtagt tctttttatt
    10801 tttatttcct agtagtctac ttactgcagc ttgactgcga ttatcttctg ccatcaaaat
    10861 caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca gctgttgagg
    10921 gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg gttattgttc
    10981 tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg gttgctgcag
    11041 tcgtcatttc tttagaaatg ttataacgct tattatactt agtaaatagg actcctcgta
    11101 cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt aactttatta
    11161 gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca gaaacagtaa
    11221 atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata taatcatagt
    11281 tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact tgagtaaatt
    11341 ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct ttatagtcca
    11401 gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta ggttggtttg
    11461 ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca atgtccacta
    11521 aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg ctagtcgtag
    11581 ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt aaaatatccc
    11641 ccattcatct tatattataa tataattata tcataatatt gtgatattgc aatatcgtat
    11701 atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat cggttcggat
    11761 ataaagatta ttcatatgtt attcgaaagt aaaataatca ctttttatta ctttaaaatt
    11821 ttttattaat cataagaaat atgttttgcg agcagcaact agaataattt aaacattatt
    11881 aaactgtcta tattgttact aataattccc ttcttatagt gcattttctt agaaaaaaac
    11941 aatattacga tatcatgata ttaagatatc gtaatattat acaattgtga ttgatattat
    12001 atatgttttt ttattttttt atcatgttta atcttgaagg aatcatattc tttttctaaa
    12061 gacaggagct tttcataaac atcagacatg tttaaactag aggccaggct taaatcataa
    12121 acgaatgaag caggtaatga ttttattcta cgttgtcggg ttatccagct tgcaaccgtt
    12181 ccttgtgggt aggcatataa ctcacaaaat tgttctacag tgattcctaa attcttgata
    12241 atgtaaacat tgatcgggtg cgagtaaaca aatgtattga tagacatggt gcgtaagcct
    12301 actttctttt attattgcgt ttgcaataat agtttaacac acgcattatt ctagtatcta
    12361 ctcctatttg taaaaacaaa aaaggattca tagagataac tctatagaat ccgtaaaata
    12421 ccttatatat ataacgggaa aatataaaac ctaaaattat gataacctgc tgcagcttct
    12481 acatagaaag agaagcgctc aacaccaacc tcatttatca aacgttggcc ataaccccaa
    12541 atctcttctg atagctgatc aaaggttata tactttagct catattgctg gataatgttc
    12601 attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt tcgtcgtagt
    12661 gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc ttgccaacaa
    12721 tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat actgatctat
    12781 tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt tgttcttttg
    12841 ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta tgatcagata
    12901 aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt tttaattccc
    12961 ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct agcgctttct
    13021 aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat cttgtcaata
    13081 attttatcta aattttcttc gttaatttgc ttttgtggat cactaaataa atccagctga
    13141 agcgaatcgg tgtacacaag cttgctatag gttattccaa cgtgccttac ttcttgtcct
    13201 tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt attatctgtg
    13261 ataggtattt tcatctggtg tgaaaatcct ggtctcgttt ctaagatcga cgtaccaatg
    13321 tttaaatgaa cacatcctgt tttacaatta tgctgcctga tacgaatggc tacttgttcc
    13381 gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg tggtaacact
    13441 tgtgaattac cataagattt ttcctttgtc ggttctggcg ggattgctat atctgttcga
    13501 tcgattccgt tagcatggaa gtacagctgt aatccaatca cacctaatct attcttaatc
    13561 gtataaggat tccagttagc aaggtctcta atgctcaaaa ttcccatttg gttgagcctt
    13621 tttttcattc gagaaccaat tccccaaaag tccgtcattt cgggaatatt ccatactttc
    13681 tcaggaacgt tttcgtacgt ccattccgca ataaatcctt cattatgctt tgcttcattg
    13741 tctaaggcta atttagccaa aaggggatta tcgccgacgc ctaccgtagc aatcaaacct
    13801 aactcttctt taatacgttc ttggatcatt tgagcgagct tcttccttcg ctgacttcgt
    13861 gtttcttcag tcgtaaaaag attcagtgat tttgtcactt ttaaaatcga ttcatcgatc
    13921 gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt tacctgcata
    13981 tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt aggaaatggt
    14041 tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt tgcttcagga
    14101 gaagaagcta atatcaatcc tgaaccagta ttatcagatc gactcataac aacaagttct
    14161 gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa gcttttcata
    14221 tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa taacactcca
    14281 ttcttccaca ttatacaaac atatgttcga tgttgtaaag aagaaatagc taaatacata
    14341 aaaaaagaag cataggtatg ctatcaccct gcttcttctt atgatttgta tgatcaattt
    14401 attctatcac tttactaatt aatttgaaaa tctaataaaa actctcactc taaaagagtg
    14461 agagactgca aattagagta cggacttttt tggagttccg ttctttaata ttaacaaatg
    14521 aataaaatcc ttacaacatt tga
//
LOCUS       DAFKHN010000062        13898 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFKHN010000062 DAFKHN010000000
VERSION     DAFKHN010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.062"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            148..1599
                     /locus_tag="LY912_002020"
     CDS             148..1599
                     /locus_tag="LY912_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBM6955683.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            1948..2580
                     /locus_tag="LY912_002021"
     CDS             1948..2580
                     /locus_tag="LY912_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBM6955684.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            3168..4607
                     /locus_tag="LY912_002022"
     CDS             3168..4607
                     /locus_tag="LY912_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6955685.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4902..5120
                     /locus_tag="LY912_002023"
                     /pseudo
     CDS             4902..5120
                     /locus_tag="LY912_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5369..5584
                     /locus_tag="LY912_002024"
     CDS             5369..5584
                     /locus_tag="LY912_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955686.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5801..6057)
                     /locus_tag="LY912_002025"
                     /pseudo
     CDS             complement(5801..6057)
                     /locus_tag="LY912_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6244..7155)
                     /locus_tag="LY912_002026"
     CDS             complement(6244..7155)
                     /locus_tag="LY912_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBM6955687.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKYFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(7174..8178)
                     /locus_tag="LY912_002027"
     CDS             complement(7174..8178)
                     /locus_tag="LY912_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBM6955688.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(8175..10298)
                     /locus_tag="LY912_002028"
     CDS             complement(8175..10298)
                     /locus_tag="LY912_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBM6955689.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10303..12750)
                     /locus_tag="LY912_002029"
     CDS             complement(10303..12750)
                     /locus_tag="LY912_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBM6955690.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLTYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12737..13126)
                     /locus_tag="LY912_002030"
     CDS             complement(12737..13126)
                     /locus_tag="LY912_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBM6955691.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(13186..13689)
                     /locus_tag="LY912_002031"
     CDS             complement(13186..13689)
                     /locus_tag="LY912_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBM6955692.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13702..13863)
                     /locus_tag="LY912_002032"
     CDS             complement(13702..13863)
                     /locus_tag="LY912_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955693.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         4302 a         2727 c         2532 g         4337 t
ORIGIN      
        1 ttaaaggcag taacaggatt aaacattgaa acataatcgt tactaaatga aatcaagaaa
       61 tatactgtat tactcaattc attgaaaata tttatcataa tttttaatag aaaacactat
      121 taaagagaaa aaagagaggt aaatcaaatg aaaaaatctt taaaacttgc atcagcagtt
      181 atattaatgt cccaactcct tatagcaaca cctttccatg tgttggcaag cgaaaattca
      241 acatacaaaa ttgcaaaaga aagaaccgag acgactgaaa tgagtaattc cgatgtaaca
      301 gcagagagta gtgaactttt gacaacttca tcaagtgaaa gtagtacgac ttcaaatgcc
      361 gagtcttcaa caacttcatc aagtgaaagt agtacgactt caaatgccga gtcttcaaca
      421 acttcatcaa gtgaaagtag tacgacttca aatgccgagt cttcaacaac ttcgtcaagt
      481 gaaagtagta cgatttcaag taccgaatct tcaacaactt caagtagtac aagtgaaata
      541 acttcttcga aagtgacaaa accaaaccat atagaatctt caaaaaagga agcgccaaaa
      601 acggaaggac aaacaaaaac tttttcgaca ccacagcaaa tagaatcaac agaatctttc
      661 caatcacaac caatactatc tggtaatgaa gaaattcatt ttgacaaaaa tgaatctgta
      721 gaaaatttta ttatgaaaat tggtgagtct gcgagaaaaa ttggtcagaa atatgattta
      781 tatgcttctg ttatgattgc acaagcgatc ttagaatctg ccagtggtca aagccagtta
      841 gctcaggcac cgaattacaa tttatttggg ataaaaggaa cttataatgg aaactttgtc
      901 attatggtaa caaacgaaga tttgggtaat ggaacgcttt atacgaccca atcaaaattt
      961 agagtgtatg aaaactatga ggaaagcttt gaagattatg ccaaattatt aactaaggga
     1021 attagtggaa ataaagattt ttatgcagga gcattaaaag ctaatagtaa aacatatcga
     1081 gaagcaacta aattccttac aggacggtat gcaacagata cacaatacta tttgaagcta
     1141 aatgaattaa ttaaaaccta cgatttaacc aactatgata aagaagttaa aggtccacaa
     1201 atgagtaaga ctggatacca agtgcctatt cataattatt caataaccag tttgtttgga
     1261 aatcgtggaa atgaatttca ccgaggactt gatatggcag ctacacaggg tgagccgatt
     1321 catgcagtta aagctggtaa ggttgttaaa gcagagtttc actactcttg gggaaattac
     1381 gtggtgatac aacacgaaga tggatcaacc gcgttatatg ctcaccagca acaataccta
     1441 gtaaaaactg gagataatgt tttgcaagga caaataattg gctatgtagg aagtactggg
     1501 aatagtactg gcccacacct tcatttggaa atttgcaaag atagtagtct ttctcagagc
     1561 atgttagttg atccgaaaac cttattattc ggagactaaa aaaggtaatc aatctgacaa
     1621 agtaacaaga aaatggttgg attcttagac ctttgatcag gatattgaga ctggaattga
     1681 tatctcgatt acgatgggtt tgacaaataa aacaagtcca ttatcgaata tcgagtgtat
     1741 tattgccgtc tttatgctca tattttgagc aggtttcact agatgaaaac aatttatcta
     1801 tcttgaggat ttcgtgtacg tatcgttcag tcttgtattg taaattagtc ataaaatcag
     1861 actaagaaaa attggaaata tttttttctg atttattaaa agttaattga aattatatgg
     1921 tacttctttc ttgggagggt aggtgcagtg aaggaaagat atggtcacct tactgttgtt
     1981 gaggagatta ctcataatgg atataaaaaa tatcgttgcc tatgtgactg tgggaatgaa
     2041 acgattgtat atcgatcaaa cttactaaca ggtagaacca aaagttgtgg atgtggaaat
     2101 tataaaaata ggcataaata taaaaatttg acaaataaaa cttttggtaa gttagttgca
     2161 atcaagccaa ctaaactgcg aagtgaagga actgttgttt gggaatgtca atgtctgtgt
     2221 gggagaaaaa agttagtatc ggcaaagcga cttctaaaag gtgatgtaaa aagctgtgga
     2281 tgtttgaaat caaaaaagca tcacattgaa aataaaaaat tcggattact tactgcaaag
     2341 tatcctttgg acaataactg ttcatggaaa acaaaatggg tttgtcattg tgagtgtggc
     2401 agtatgtgtg agataagtta tagtaactta ttttttggac atactcaaag ttgtggatgt
     2461 ttaaaaaggc aagaaacaag gacatgtgtt gaagggacag taatagagtg tctaacgtca
     2521 aaattaccga aaaataatac aagtggtgtt aagggagttt atcgttctaa agagaaatag
     2581 attgcgtata taactttaaa aaaaaagagg tactatttag gatcgtatga ttctattaag
     2641 agtgcagctc aagctagaaa agatgctgaa aataaattgt ttcaaccttt gattgacaaa
     2701 tatcgaggta atcattaatt attgtggata ataattaaca gtgatatata aacatctata
     2761 atatattatt catactattg atatttagta taatcctatg gaattgaata tcatagcaat
     2821 gtatttgaaa agcaaattgg aaaacaaata ggtgcaacac cataaatatg aaaaaattgg
     2881 gaaaaagtag aatggaaatt tgcttacgtc tcacgagata gctcacacta ttaatctgaa
     2941 gaacaatgaa gtcgactttt agaaattgct agaagaaagt aaagcgaatt atcactagtt
     3001 actatagagt aagttcaaat aaagcatctc caacttacat ggttacatga ggatatcaaa
     3061 tcgaaattac tcaagcttcc tatggctaga gtcgcgagaa gttgttgggc agtagacata
     3121 ggttatattg ttcttagcta cacgatcatt agaaaggaaa tcctattatg tatagttatc
     3181 aagaagatgc aaaagtccaa aaaaatcgct ggtggatttt gattgctata tctatgttta
     3241 ccttcatgtc cacattggat ggcagtattg tcaatattgc actacctacc atctcagatg
     3301 atatgggcat accaatgaat caagcggaat gggtagtgtc cgtttatctg atgattgtct
     3361 gttcttgttt gttgctgttt ggtaaaattg gcgatagccg tgggaaaatc aaagtatttc
     3421 ggattggtac gctgatcttt gtcttgggat cgctgttgtg tgggttcaat cattcgctag
     3481 gtattttatt gttcgcacgg gtggtacaag ccattggtgc tagtatgact atggctacaa
     3541 atgccggaat catcacggaa gtctttccca tacatgaacg tggtcgggca ttgggagcaa
     3601 taggtgcgtt tgtttcatta ggctcgattg ctggaccagg tcttggcggc ttgattttgt
     3661 cccaattttc ttgggcgtac attttttgga tcaatgtacc ggtgggaatc gtaacgatgt
     3721 tgattgctga aaaattctta ccaaaagata tcaccatgag cggccataca atcgatggag
     3781 ggggctttgc tgccattgcg gctacgatta tcagcttttt tggagcaatc tttttggggc
     3841 aagaaagtgg ctttttccat ccagtccccc ttgtactgtt cgtaatttca gtgattgcct
     3901 ttgtcagctt tttaaaagtt gaaaagaaag cagcctctcc attgatttct ttcggtattt
     3961 ttaagaacaa gatttttacc atgagcttga ttacagcctt gttgattttt tcttccaact
     4021 tctttgtcaa tgtagtgatt cctttttatc tgcaaaatgc tcgcgggttg agtcctagct
     4081 atgctgggct gttgatgatg gtctttcctt tgatgatggt cgtcggggcg cctttaagcg
     4141 gctacctgac cgaccgggtt ggcccggaga ttttggtatt agtaggcttg ggcttattgt
     4201 cggtaaccca ggtcatgtat atgtttttgt cagtggactc tcctttgtgg ctatacattg
     4261 tcgctactgc catcatgggt gccggcaatg ccttgttcca gtcccccaat aatacgatgg
     4321 ttatgagctc ggtcactatc gaaaacttgg gactggcagg ctcgatgaat tcctttgccc
     4381 gaaatttggg gatggtcagc gggatttcgc tttctacgac ggtcttatat caagcgatgt
     4441 ctgctaagat gggccagcaa gtaactaact atatcgcaaa tcggccggat gtctttttat
     4501 atggaatgaa gattaccttt ttaggcagct ttgttttgtg ttttgttgcc tttttcctga
     4561 ctatctggcg tatcaaaaaa caaggaggta ttcagaaaaa tgtctgaaaa aaccactgtt
     4621 gaagaatttt tggaggcctg cgtatgggtg agtgggattt ccatggatga tggaagatga
     4681 agtgaacttc taaaagccga aaaactcaag tattatcttc aaaatactag tgctcaatga
     4741 gatgcttgat ttgatcacaa gaagactgcg aaagccgctg gcaaccgcaa gctaggtatc
     4801 ccaccgatgg actacgtttt agaggctact ggttatgaat acggagccaa cgctctcatc
     4861 tgcataagaa tacatcaccc agattatgta aagattttcg atacttctgt caaaaaatca
     4921 ttaagataga taaatgattt ccgtctagtc aaattggttc agaatgtaga cacacagatg
     4981 gtaagaagtc actcacaatt cgagaatgga cttgtcctat ttgccgtata catcataatc
     5041 gaaacgtcaa cgatagtatc aatattttga ccaagggcta tgaatacaag cattgcctta
     5101 gaaaacatca agaaccttag gaacaacggg gatagcttgg ttaataagag ataccgctgt
     5161 ttaggcttgc aagtatactc ttttatcaag aattccgtgg ctttagtcat gagaggctta
     5221 atactatgaa aattttcttt agcatttttg atttaggttc cttttctaat tataataaga
     5281 tgaccactac agtaacctac tgaaatatat aaacagccac tgtagtacca ttttcaaagt
     5341 agtctatgag aggagaatct tcattcttat gaacgctgga attgcggata tgaatttaat
     5401 aaaaaaaacc cttaatgatt ttacttccaa ttcaatatca aaaggtactg gtatcaattt
     5461 aagcacaata aaaaagctga aaagtggtga aagatcagtg gaaaagctga atcttttaga
     5521 tgctataaaa ataacggaat ttgctatgaa aaatggaaaa gctgagattg aaatatggag
     5581 ataattatcg tctagtgaat tacttgccac ttagctgaat ttaacgatcc ttggtgcttg
     5641 aagggggaga ttcttgggaa tagagcatac ttgcaagcct atgtctttac taacaacgat
     5701 atctcttatt aaccaagcta tccccgtagt tctaaggctt ttacttttat ctaagcaata
     5761 atcgtattca aaggaaattt ttgaccctta gaaagtctca ttttatcaga cgtgagctta
     5821 ggcattgctg aattttgtta attcggtttt aggttgtgct ttgagcataa tatgaaagta
     5881 ttctttatca cgatttcatt catctaaggt aatgtgatgt gattctgaaa ttctttcaaa
     5941 ggcagttttt gcataagctg acattacatc atcaatgaca tgtttacaat gtttcactac
     6001 taaaataagg gggtaaccaa gaagaaaaac tgaatgatta tttgtatcta attccatggt
     6061 atatcaacca tttcctatat agactgatta tgacatggat taaaataaaa aggcactatg
     6121 tcttaattgt cggttttcga gttaccgaat ggcattcatc acccacctat agaggatggg
     6181 cgacttctgc ctgaaataag ttacactact tataacttct aataaaatta gattgagtca
     6241 ttattattta acatcaacga ttttccagtt tccatttttt tgtaatacta atttgtactg
     6301 aaagtagcta gtggtttttg atacattatc aaggtatttt atctttgtac tcactagaaa
     6361 atattttccg ttttgtagat aaactggatt ctctaactcc gaaaacttta agtcaatatt
     6421 gattggtcgc atcgcaccat tttcaacata atactccaat tctttttcag aagctgatgg
     6481 ataaagttta aaaaatgttt ctaaaaaatc ggtgatttct tccgttgttt tggcatcaat
     6541 ttctgaatcg ttttctactt gttttgcttc atattttgcc ttgtctggct ttccaatcat
     6601 tgttggcaaa ctagttacta aatgattcct gttttcatct tcaaagattg tcactcgata
     6661 tgcagaagaa attgattgcg tcttttttcc ctctgtaata tgttgctcca ctaaaaatga
     6721 aacgacaaat tcttccgagt gtttttcaac atctagaatt tttacagatt gaacttcgga
     6781 actcgtggga atatctgctc gaaccatatc ttggattaaa gcgagaccgt tttctgtaag
     6841 gtactgttcg agattactca ttctcttttc aattgcttct ttgttatttt tccatgaaaa
     6901 atattctttc gcaaaatcct ctgtaaaact ttcaacgcca gaagtattca ctaccttctc
     6961 ttttataacc actttttcat gagttgtatg ttgatcaatg gcggtgaaat ttttataaac
     7021 gccaaaagca agactacaag acaataaaag ccaaagggca agcaccattt ttcgatgctt
     7081 acccacggat acaactcgtt cttttttctt ttttgggctc ttttcctttt gattccgttc
     7141 aatttttatc ttcattcttt ttcctctttt ctcttatttg tatcggccag ctccgataag
     7201 atgctgccgc caatagtttt ccgttagatt cgtccacccc actggatctc ctgcatgaaa
     7261 catgcgattc tcccctgcgt aaatgcccac atgggtcaca taagtaccgg catcataggt
     7321 tgaatgaaag aaaactaaat cacctggttt ggcatctttt agatcaatat gagtcatggc
     7381 atcatattga tcctgagcca cccgaggaag tttcaggtca actttggcat aacaccattg
     7441 ggtcaagcca ctacaatcaa accccgtttc tggacttgag ccaccaaaca cataggccgt
     7501 tccttcatac ttaaatgcct catcaaaaat ttcttggact attttgtcat caaactgagt
     7561 tgtagttagg tattgcttca ctaataaaca gtaaaacata ttgccataat tataccgcca
     7621 cccaccattt tccttaatcg cgattgggtt ggggtaatcg actttttgac cacctgattt
     7681 ttcctttgaa aaagattcag ctaaagcaaa actatgcttc ttcccgtttt tcccgacatg
     7741 atctagatac ccgccaccat agttataggc ctgaataata ctatcttgat cacaccctag
     7801 ttctttggaa cgcttaacca aagacgcaaa atagagacag ccttgtttga tggatgcctc
     7861 ggtacttaat gaattaggtg gtaatccggc tgactcagaa ctttgcataa cgtcttccat
     7921 tgtgccacca gattccactt gaataatcgc caaaagaatt ggaatatact ctgttatatc
     7981 cgattctttg gcatactttt ccaccattgc acggtgtttc aatacttctt ctgagacact
     8041 agttccgcca ggagaagtgc cagaactacc atttccctca ctgtcttcac caaacaacaa
     8101 acccacacac atcaaaatac ccataaaaga gatggtcaga aaagttaatg aaataacacc
     8161 cactttcttc aagttcattt tttctcacct gaccttgatt ttggacgatg gttcattctt
     8221 ttttgtactt tttgattggt ctgctttggc agagtggacc tctgtttcac ttgttggaaa
     8281 gaatttttct tacttgctga ttggcttttc ccttttgaaa tgatttcttg actagttagt
     8341 tttcgtttga tttcgggatt cagatttgct ctcacaatcc gctttggtgc ttcttttttc
     8401 agcatcatat ctttctgagg ttgagctgct ttatctattg gaatattcgc ccttcttttt
     8461 ccctgacgat ttgttgcttc actcagtatc ttgcgttttt cgtccatttt cgcatttctt
     8521 cgttgtcgtt gtttttctcg caaatccact cgatccgctt tttcttggaa cagtccgcgc
     8581 ttgaattctt ctggtgcttt tttcgacttt tcgattcctt tatggagatt gtatttcaaa
     8641 ttcgttggcg tattccttac ctgatccttt acttgtttag tcttatcttt caccaaagct
     8701 tgggtatcca aaactttgcc gatttttctc ccagccaaat tcattcggga ttgtttctta
     8761 ttatttgaaa ctggattctc cttagttaag tcagatagta tttcgtgatc gttcggtaat
     8821 cgtgaattct ttcgtagaga agaaccggat ggcttaaatt tggattttga ttgttccttt
     8881 gccaacttat ttccgactgc tgcaccacca ccaaaagcca aagctcgtcc cacatttcga
     8941 ttgagttgcc gcaattttcg attcattaac atttgcggtt ttcgcatgac gcgtcttccc
     9001 attgactggc tatcattact ctggaggttg aacatactca taatgtcgcc caatttgaaa
     9061 tagataccgg caaaggtcac aatttgcaga aaagcaacca tgaaaaatgg ataggttgcc
     9121 gaaatattga aaaacatcgt ggagatgcta aatgcagtcg taatcaccaa agtaacaccc
     9181 gctcgcatca taatcgtatt gaataaacga ataatcgcct tctttcctaa actttcataa
     9241 gtcggcaaca tggacaataa gaaactaatt ggcagaaaca tcgcaaagat aatgaagaga
     9301 atttgcgaga acaacataat ccctgttaga agaaaaacaa agaaggaaat gccaatattg
     9361 aacaatacca aaaagaccac ggtccctaaa cggttcatgg tcttggtaat actgagattc
     9421 gcattgtcat tgtcttcaat ctctgccttg accgcttctt cccgatcttt gcctttgttt
     9481 tcatctggac tcacagatag aatcttgttg acccggtctt caccaatttc ttctatgttg
     9541 gaatcatcaa attgcagtag taaccaaggt tgttggactt gaatcgaaaa caaactatcc
     9601 cgaatcaaat ccacactatc ttttccttgg ctttctgaat tgggtacaac gatctcggtt
     9661 ccaagggtaa gggccgcttc actaacatct gagctaaagt cattgatttt tgtgatatag
     9721 gtaggcgcat aagcaatgaa cgaacccgat agtagaaaaa tcatcacaaa attaatcacg
     9781 gctcgaactg ctttcgtggt ttctcgtttt aataatccgg tatacgccac atacaccccc
     9841 agagctaaaa tcatcaataa tagaaaccca aaataaaatc cggaggtctg gagtccattt
     9901 tcagtaatac cagccaatgt ttggatattc tttccaatac tttcagccgt atccgaaatg
     9961 aaatctaatt tgtaagcctc ttgaaccaca taacccgtgg cgttcgacaa atacaaactc
    10021 accgtccaaa tgaaattagt aatggcataa agaccataca tcacgctttt ccctaagcca
    10081 tcaccccaat tccaaggcaa ccaatcccaa gagctatcca caaagaaatc tagttgatag
    10141 ttgttcagtg aatatttgga atatagattt cctgcttcaa ctgtatcatc aactagccct
    10201 gtcgcctcgg ctaccgtacc aactaaactc aatagaacta tcagagtgag tatgctaata
    10261 aaaacgattc ccacaatccg aaaaagtttc tttttcatcc cctcactcca ttctctcttg
    10321 aacaggtgga cgggtatcaa aggcatggaa gagttcttca aagactggat gtacctgaac
    10381 cacgcctacc cgaccataca aatcctgcat caagcattgg ccattttcca aatctcgtag
    10441 gcgtttttga ttgctttcat cttctcgatc caagccaaag aattccaagg ttttcttgat
    10501 ttcatgaata tcggtactgc gaaacgcaaa cttcaacccg atattattct tcaagcgttc
    10561 atccagtaaa tcatcactat tttgcgtgac aaagtaaacc ccggcattca tagcccgccc
    10621 agcacgaacg agcttattcg ataatgtttt cccttgcgct acttgaagaa aactccacgc
    10681 ctcatctaag tctacaattt tgaagatttc tcgattacta tggataaagt ccaaggcaaa
    10741 agtggaaatg acgattagca tggaaacact aagcaattcc atggtggtat attcttcaaa
    10801 agtggtttct gcatctggta aaaccaaatc cgctacttga atgatattta actgcctatc
    10861 taaactaatc gactgggtaa tcgaaccatc tgagaaaagc aaatgggcaa aatcataatc
    10921 ggtaaaggac tcgatgtgat ccgcgatatt ttccgcaact ggtgagcctt cttttcgaag
    10981 ctcattaatt acttgtaata atccccgttg attgctttgg gtaaccgtcc gaatggcctt
    11041 acgcaacact ggaaacttct ccccatctcg actagaaatt cctgttaaaa aggtcagaat
    11101 atcaattgct agactttcag aatccttctt tttctccata atcacataag gatcaagtaa
    11161 tccttgattt tttggcttac tagttaagtt gagaatattg atttcatccg caatttctgg
    11221 caaggtttct ttccagccac cccgttcccc ttttggatcg acaatcacag cttgtccacc
    11281 aaaaaggacg gcgtaataaa ctaagagatt gttactaaag gactttccgc caccgagtga
    11341 accgaggaat gccgctgcta gcgcattggt aactgaatcc ttgacccctt gtgaggccaa
    11401 tgccggtttc aggtaaacat tgcgccccgt atctacgtta taaccaaagt aaatgccttc
    11461 caactcccct aacatctgag tggcgccaaa accaagtccg gcgagaaaat cagacgtaac
    11521 atactggata taatcattca tgtatcgctt actagaaggt aagaattctt catgtagccc
    11581 catcatatcg ccaaaaggcc ggactagttt tacattggta tcatcataaa aatctagcac
    11641 ttcatcacac cggcgcttta gttcatctac tgattcggca cttactcgaa ccacataggt
    11701 cagtttgtac atggattctt tggactgatc caaggtagtt tccaattcat ctacggaatc
    11761 caatgcatct aagacattgg aatttgtttc attgtcagat tgataggcat ggttgtccaa
    11821 gtcttttaat tcctttttct tattgcgaac ggtagcaagt gcctttttgt tcgtcacaat
    11881 ctccacattc atactagtgt caattgggaa tgtaaattgt tgttgctggt aatagaaaag
    11941 ttctgaggag ggaaactcca tttcccccac aattgtatta attgttaagt acgctacata
    12001 tgattcatga ttctcatgtt ccatgcataa gtaccggggc ttttcttcaa tcaaacaacg
    12061 actgggacgt aataagtcgt aacgtttcac caaagtttcc gacttcagct ttttctttgg
    12121 tagctgaaat tcatattctt caaatggtgt acccttttcg ccatagatat gttcaatcaa
    12181 atacatcaga tcactcggtg tgactcgtct gactttaaat cttcgagcca atttactttc
    12241 cattagtttt tcaagcttgg tatatcggcg aatttcttca ttggataagg aaacaaaatc
    12301 gcccatcaaa tgatgattca ctccatagac aaattcttga aagccggaga agaaagattt
    12361 cttgagattc tttagattga cctcttcatc tgtcgcaatc agtttgaagc caataaaaaa
    12421 gcgataatca atctgactat cgccaatcat ggatactaat gcctctgtct gtaaatcaat
    12481 tcgttgtttc gctacttctg ttaatcgccc ggtaatttcc ttttttgatc gttcttgcgt
    12541 ggcacgaata ctactttctg tggcaatttg taaggcatga atcttgcctt cacgattttg
    12601 cgcaatcaat tgacgaaagt tatcgtggac ttgatatttc tgttcaggtg acaaaaagga
    12661 gtaattgtaa ggtattaact catagtaggc aaaacattct ccctcttgat taaagacaag
    12721 attattttca atatacttaa tcgggtacat agttcacact ccttaccaga gtaatgggtt
    12781 cgtcccatcg tttcttctgt tctttgactt tctttcctgc gaaagtgacc ttaaatcgta
    12841 agtgatagct aataaaagat cgtaaaaatc ccaatggttt cttaccgtca aacgtttttt
    12901 gcgacatgaa ccaagtaact gccaccggta tacctaagta ttttaaaaag gccccctcta
    12961 tcatagatag tggaggcaca tgggcaaata cgatgacaaa cagcaaggat aaaacaaacc
    13021 aagccatctg gttaaaagtc acaggaaaag gcagttgaaa gtcattaatt gcataaatga
    13081 ccttttcaac tgcccaaata ctggtgtagc tttttatttt cttcatcaaa tcattccttt
    13141 aaaaagaagg atagtttaga aatcaactac ccttcaataa ttttgttaat atggatactc
    13201 aaaaacacct cgactcgtta ccaaataatt gcctccaatc tccaagtctc taccacacgc
    13261 atcaaaatca atatacgtct tcaagtgttc tggtacttct ccaaaatcac cagcttctac
    13321 aatcaagaaa tatgctacat cactcatatc atcgcaatct ggataataga taatatcatc
    13381 cacatgctct accatctcct caaaagaatt gaagaaagca tgttgaatct cagaagcaac
    13441 ttcaccaact ggcgttcctt caagttcctc cgctaagcca cacaaccgat taatttcctc
    13501 aattggcgta tactcatcaa tctcaaaggg aagttcataa tcatgaattg catattcctc
    13561 gtattcgtca tttaacccaa ttcgttcttt cacttcatca aaatcgacag gtggggtaaa
    13621 ccacgccccc accaattcac cttcgttata tttcccgagg ttcgcaatat aaacacgcat
    13681 ctgttccatc gtgcttcccc cttacgcacc gacaattcgg ttaaacaaac tgagtaagac
    13741 atccttcacc ccagaagcat taaagaccaa tccgaccgca atcaaagcaa tcaccaaaaa
    13801 gccaatcagt ttggaaaact cccgcttaaa tcctaaaaac aaaccaatga ccacaattgc
    13861 cagtaagact aaggattggg cattggttaa aaaccatt
//
LOCUS       DAFKHN010000063        13818 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFKHN010000063 DAFKHN010000000
VERSION     DAFKHN010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.063"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(163..2160)
                     /gene="tkt"
                     /locus_tag="LY912_002033"
     CDS             complement(163..2160)
                     /gene="tkt"
                     /locus_tag="LY912_002033"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBM6955694.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2262..2513)
                     /locus_tag="LY912_002034"
     CDS             complement(2262..2513)
                     /locus_tag="LY912_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBM6955695.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2660..3283
                     /gene="lexA"
                     /locus_tag="LY912_002035"
     CDS             2660..3283
                     /gene="lexA"
                     /locus_tag="LY912_002035"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBM6955696.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3463..3681
                     /locus_tag="LY912_002036"
     CDS             3463..3681
                     /locus_tag="LY912_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955697.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3970..4482)
                     /locus_tag="LY912_002037"
     CDS             complement(3970..4482)
                     /locus_tag="LY912_002037"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBM6955698.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="LY912_002038"
     CDS             complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="LY912_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBM6955699.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6935..7378)
                     /locus_tag="LY912_002039"
     CDS             complement(6935..7378)
                     /locus_tag="LY912_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBM6955700.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7379..8167)
                     /locus_tag="LY912_002040"
     CDS             complement(7379..8167)
                     /locus_tag="LY912_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBM6955701.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8164..9105)
                     /locus_tag="LY912_002041"
     CDS             complement(8164..9105)
                     /locus_tag="LY912_002041"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBM6955702.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9282..9869)
                     /locus_tag="LY912_002042"
     CDS             complement(9282..9869)
                     /locus_tag="LY912_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBM6955703.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="LY912_002043"
     CDS             complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="LY912_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBM6955704.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11700..12710
                     /gene="gap"
                     /locus_tag="LY912_002044"
     CDS             11700..12710
                     /gene="gap"
                     /locus_tag="LY912_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBM6955705.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12795..13730)
                     /locus_tag="LY912_002045"
     CDS             complement(12795..13730)
                     /locus_tag="LY912_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBM6955706.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3810 a         3096 c         2436 g         4476 t
ORIGIN      
        1 tctcaagaaa cacaaactaa tccgaagaat tctttgtttt gtcatttaaa tgtaacatag
       61 ccgaaaacga aaagtaatat tgatttattc ttctaacaca taaagaacag ctgtctccaa
      121 cttgcagaca gctgttctta tcagtcaaac aattgcttgg atctatgata gttgattgta
      181 cgtattcacg acattttcta ctgtaaatcc aaattcttct aaaattttag tgccaggggc
      241 agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct gttcctacgt agcgttccca
      301 tccaaatgat gcagcagctt cgatagccac acgtttcttc actgatttag gaagtacact
      361 ttctttatat tcagaagatt gtttttcaaa gaggtcaaag cttggcatag aaacaacaga
      421 aacatctttg cctttttcag ccaattcttt ttgagctttc acagccaaat caacttcaga
      481 acctgttgca atcaaaatac cttctggtgt ttctccttgt gatggagaaa gaacatacgc
      541 gccttttttc accatttcat ctgctacttc ttttgtagaa ggcaatactg gaaggttttg
      601 acgactcaat acaaggatag taggcgcatc tgttgtctcc atcgctactt tccaagcagc
      661 acgtgtttca tttccgtctg ccggacgaat cacttgaaca ccaggcatgc agcgaacaga
      721 tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct ccgacagcaa ccgagtcatg
      781 tgttaagacg taaacaacag gagtatgttg gattgctgct aaacgaactg ctggtcttag
      841 ataatcgaca aagacaaaga atgttccacc gtagatacga gttccgccat gaagttggat
      901 accattcata gccgaagcca ttgcaaattc gcggacaccg aaccagatgt tgcgtccttc
      961 ataatgttca ggagtgaaat ctttatctgc agccaccatt gtattattgg aacctgacaa
     1021 gtccgctgaa ccaccccaga agcttggtat agctttcgat aattcttgga tgacttcttt
     1081 acttgaaaca cggcttgctt gactgcttcc aacttcataa gttggcaatt ctgcatccca
     1141 gttttctggt agtttgccat caaaagcatc ttcaaattgt tgtgctaatt caggataagc
     1201 ttttttataa ttggcaaaca tttcattcca tgcatcttca gctttttgtc cttcttctat
     1261 catcgtttga tggaagcggg cagctacttc ttctggaaca gtgaaatctg gatactccca
     1321 accataaact tctttagcca tcttgatgcc atcttcacca agaggagcac catgaacagc
     1381 agatgttcct tctttaggag caccatagcc gatgactgtt tttacttcga tcaatgttgg
     1441 tttgtctgtt tcagcttttg cttcttcaat cgctttagag attgcttcta ggtcatttcc
     1501 gtctttcact aagatatgtt gccagccata tgcttcatag cgagcaccaa cgttttctgt
     1561 gaaagctttt gaagttggac cgtctagtga aatatcgttt gaatcgtata aaacgatcaa
     1621 tttccctagt ttcatatgac ctgccatcga acttgcttct tgagataccc cttccatcaa
     1681 gtctccgtca ccgcatattg catacgtata gtgatccatc acattaaagt tttctttgtt
     1741 atacgttgct gcaaggtgcg cttctgccat tgccataccg acagccattg caatcccttg
     1801 tcctaatggc cctgtagtgg cttctacacc atctgtatga tgtacttcag gatgtcctgg
     1861 tgttttagaa tcccattgac ggaattgttt caaatcatcg attgtcactt gatagccagc
     1921 taaatgaagc aagctataca acattgctga cccatgtcct gccgaaagaa cgaaacggtc
     1981 gcggtcagcc cagttttttg atgtcgttgg atttactttc aggtgttttg tccataacgc
     2041 atatgccata ggtgctgcgc ccatcggcaa tccaggatgt cctgagtttg ctttttggac
     2101 tgcttcaata cttaatgtac gaattgtgtt aacgccaagt tggtcaattt tgtcaaacaa
     2161 aataacccct cctattaatt taggtttttt ttacctttat ttcttacact ttcattctat
     2221 aagatgtcac acgaaaaagc aatctttttc agtatttttt actaaaagtt gtcatttcgg
     2281 ttgtgtaagc cttttttctt ttggatttct tttaattttt ccggggtcac gtcattgccc
     2341 tcaggatcga cgactttcat tccttcgata tgatgacgca taccggaacg aaaagcttcc
     2401 aaatactctt tgcgcaagtt gatttgttct tgttcttcgg cttttgagag accattttcc
     2461 ttctttttac gtgcaagttc attgatccgc tctatttttt caggtgacag catgctcagc
     2521 cctcctttta ctctccttca tattatataa aaactgaaaa aaaaacaact agataaacta
     2581 aataaaatac gaacattcgt ttgatttagc gctttttata tggtactatt tatttatcaa
     2641 gtgaaagaag gtgtaccttg tggcccgaca aactgaatca agacaaatcg aagtcttacg
     2701 atatatccat gaacaagtaa cccaaaaagg atacccgccg actgtccgtg aaatcgggga
     2761 agctgttcag ctttcttcta cttctactgt tcacggtcat cttgcacggc ttgaaaaaaa
     2821 agggtttatc caaagagatc cgacgaaacc tcgtgcaatc gagttgacaa aacaaggttt
     2881 agaaaagatt gggattcgtc caacaactat tccagtactt ggcgtcgtaa cagctggaga
     2941 acccatttta gcagtagagg atgcttcaga cttctttcca atccctccta atctttcttc
     3001 cgaagaaggc agtctcttta tgctgacaat tcgtggagat agtatgatca atgctgggat
     3061 attggatggt gacaacgtga tcgttcggaa gcaagaaact gctcaaaatg gcgatattgt
     3121 cattgcaatg actgccgagg acgaagcgac ttgcaaacga ttctataaag aaaaaaactt
     3181 tttccgtctg cagcctgaaa acgacttgct cgaaccaatc atcttagatc aagtatctat
     3241 attaggacga gtagtaggac tttatcgtag tcatatctat taattgctac taattaaaag
     3301 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
     3361 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
     3421 tatacgaaca attgttcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
     3481 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
     3541 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
     3601 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
     3661 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
     3721 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
     3781 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
     3841 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
     3901 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
     3961 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
     4021 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
     4081 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
     4141 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
     4201 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
     4261 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     4321 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     4381 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     4441 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     4501 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     4561 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     4621 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     4681 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     4741 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     4801 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     4861 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     4921 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     4981 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     5041 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     5101 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     5161 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     5221 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     5281 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     5341 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     5401 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     5461 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     5521 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     5581 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     5641 atcctttagc tgatccatct tcttttaaag taaggacaag cgttggttta cccgtttcat
     5701 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     5761 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     5821 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     5881 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     5941 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     6001 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     6061 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     6121 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     6181 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     6241 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     6301 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     6361 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     6421 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     6481 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     6541 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     6601 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     6661 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     6721 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     6781 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     6841 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     6901 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     6961 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     7021 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     7081 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     7141 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     7201 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     7261 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     7321 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     7381 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     7441 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     7501 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     7561 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     7621 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     7681 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     7741 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     7801 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     7861 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     7921 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     7981 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     8041 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     8101 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     8161 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     8221 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     8281 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     8341 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     8401 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     8461 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     8521 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     8581 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     8641 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     8701 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     8761 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     8821 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     8881 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     8941 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     9001 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     9061 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     9121 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     9181 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     9241 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     9301 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     9361 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     9421 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     9481 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     9541 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     9601 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     9661 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     9721 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     9781 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     9841 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     9901 ttattttacc tttaattgta aaataagaaa agaaaagcac tctttttttc caataaaata
     9961 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
    10021 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
    10081 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
    10141 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
    10201 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
    10261 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
    10321 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
    10381 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
    10441 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
    10501 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
    10561 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
    10621 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
    10681 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
    10741 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
    10801 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
    10861 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
    10921 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
    10981 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
    11041 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
    11101 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
    11161 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
    11221 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
    11281 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
    11341 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
    11401 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
    11461 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
    11521 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
    11581 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
    11641 aattgtatta attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata
    11701 tgacagtaaa agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca
    11761 tcaaagaagt ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta
    11821 tgttagcaca attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg
    11881 caacagaaga ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg
    11941 caagcaaaat cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt
    12001 tttatacatc tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta
    12061 tttctgcccc agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag
    12121 atgaaaacga caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg
    12181 cttatttctt aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct
    12241 acacttccac acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc
    12301 gttcagctgc tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag
    12361 ttatccctga gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg
    12421 gttcattaac tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg
    12481 aagcaatcaa aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg
    12541 tttctagcga tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag
    12601 taacaactgc tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg
    12661 gatttacttg ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat
    12721 caatcgataa aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct
    12781 acttttaaac tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat
    12841 ttttcaggat ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct
    12901 tttggtccct tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct
    12961 tcgtctccat gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt
    13021 gcttcaccga aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc
    13081 ggaaatgctg gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa
    13141 gaataaccgc aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc
    13201 atcataactg ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca
    13261 ttgttttcta gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat
    13321 ccaatgtaat ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa
    13381 cccatatcat gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca
    13441 tgagccacaa gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat
    13501 ttcagaccgt cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat
    13561 ttatgtgcat ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag
    13621 tctttctcag aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca
    13681 acaatcagag ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca
    13741 tctcatttct cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc
    13801 aatgttcatt tttataac
//
LOCUS       DAFKHN010000064        13360 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFKHN010000064 DAFKHN010000000
VERSION     DAFKHN010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.064"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..359
                     /locus_tag="LY912_002046"
     CDS             <1..359
                     /locus_tag="LY912_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBM6955707.1"
                     /translation="AAVQEAPVQAEQPVVQETVQTETQAAPVAETQPAPAVTETAATP
                     ASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRY
                     GSWEAAKAFWEANGWY"
     gene            complement(443..1165)
                     /locus_tag="LY912_002047"
     CDS             complement(443..1165)
                     /locus_tag="LY912_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBM6955708.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQSYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKTVPIDHLLIETDGLHAAEWALGGIFSEKYYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1155..1892)
                     /locus_tag="LY912_002048"
     CDS             complement(1155..1892)
                     /locus_tag="LY912_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955709.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYRNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1904..2896)
                     /locus_tag="LY912_002049"
     CDS             complement(1904..2896)
                     /locus_tag="LY912_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6955710.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQETKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDITYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDNPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2911..3654)
                     /locus_tag="LY912_002050"
     CDS             complement(2911..3654)
                     /locus_tag="LY912_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955711.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3728..3832)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3895..5217)
                     /locus_tag="LY912_002051"
     CDS             complement(3895..5217)
                     /locus_tag="LY912_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBM6955712.1"
                     /translation="MKTYDAIVIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYFVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANVVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRNPPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5204..6169)
                     /locus_tag="LY912_002052"
     CDS             complement(5204..6169)
                     /locus_tag="LY912_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955713.1"
                     /translation="MTKLIEFKHVQKKYDRKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFNEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6166..7704)
                     /locus_tag="LY912_002053"
     CDS             complement(6166..7704)
                     /locus_tag="LY912_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBM6955714.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKVLNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8120..8407)
                     /locus_tag="LY912_002054"
     CDS             complement(8120..8407)
                     /locus_tag="LY912_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955715.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8541..9209
                     /locus_tag="LY912_002055"
     CDS             8541..9209
                     /locus_tag="LY912_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBM6955716.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9495..10235)
                     /locus_tag="LY912_002056"
     CDS             complement(9495..10235)
                     /locus_tag="LY912_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955717.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKGNLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKMLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10365..11312)
                     /locus_tag="LY912_002057"
     CDS             complement(10365..11312)
                     /locus_tag="LY912_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6955718.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11441..12205)
                     /locus_tag="LY912_002058"
     CDS             complement(11441..12205)
                     /locus_tag="LY912_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBM6955719.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRGSEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12209..12598)
                     /locus_tag="LY912_002059"
     CDS             complement(12209..12598)
                     /locus_tag="LY912_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955720.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12732..13274
                     /locus_tag="LY912_002060"
     CDS             12732..13274
                     /locus_tag="LY912_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBM6955721.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
BASE COUNT         3905 a         2778 c         2278 g         4399 t
ORIGIN      
        1 aagcagccgt tcaagaagca ccagtccaag ctgaacaacc tgttgtacaa gaaacggttc
       61 aaacggaaac acaagcagcg cctgttgctg aaacacaacc tgctcctgct gtaacagaaa
      121 ctgctgctac tccagcaagt acaagctctg caaaagaatg gatcgcacaa aaagaatcaa
      181 gcggttctta cacagcaacg aacggacgtt acatcggccg ttaccaatta gattcttctt
      241 acttaaatgg tgactactct gctgcaaacc aagaaagagt agcagaacaa tatgttactt
      301 cacgttatgg ttcttgggaa gcggcgaaag cattctggga agcaaacggt tggtactaag
      361 attcatttat taatcgaacg gtttactttt atacaaagaa agccaaaaag aggtgtgaca
      421 caactagtgt cacacctcct ttttatttac ctaatctaat gaaacgttcc aagttttgat
      481 aagtattttt cttaacttct tcaactgata gctctttgat ctcagcgatt gtctttaact
      541 gttcttcaag cagtgagaca taatattttt ctgaaaaaat cccccctaaa gcccactctg
      601 ctgcatgtag tccatccgtt tcaataagta agtggtcgat tgggactgtt ttagctagtt
      661 gccagactgc tgggttcttt ttcaaatcaa gaccaatgct gaaataacag cctaaatcaa
      721 tatagtcttg ttgatagtcc aaagaagaat accaatgaat caaatagtga ttagggtaag
      781 attggatata atttaagatc tctttttcgc atccttttgt atgcagtaca acaggtttct
      841 catttatggc tgcaaaagca agctgtcgct caaatacttt tttttgtgta gtcatcggta
      901 cattcgtcca aatattatct aaccctattt caccgatgat ccttgctttt ttcaaaaaag
      961 gctcaacttg ttcaaacgta tagctatctg ctttccaagg atggataccg taacttaagg
     1021 cttgagtctt acttgctgca agctgtctgt tttccttcca ttcttctggc gaatcacaat
     1081 tgatgatcgt caaaatcgtg tgttcctgct gaaggagtgc taaactctga ctcccatcta
     1141 aatgacaatg agcatcactt aacatctaat tcacctgcca ataactgata aatcgtttgc
     1201 ttcaactctg attgctgcag tagccattca cgtgaccgtc gtttttcagg cacttgaatc
     1261 tcagcaatca catgtgccgg acgggcggaa agcacaagaa tcctgtctga taaataaatt
     1321 gcttcttcga tatcatgcgt cacaagtaaa gtagtccgct ttgctttttt aggcagcttc
     1381 aacatccaat cttgcatctg ccctctggtc atagcatcta acgctccaaa tggttcatca
     1441 agaagcaagt aagaagaagg attcatgatt gttcgtaaca aggccgttcg ctgcttcatc
     1501 ccgccagata attgttccgg caaaaaatgt tcatatccgt ttaacccaaa gatatccaga
     1561 taatccctta cttgttcttc attgattgtt agatgattga ttttttgata taacgtaacg
     1621 tttcgataga cgctcagcca aggaagtaac atatcttctt gcggcatata actaaatgct
     1681 gtatggagac cagttacttt ttgatcgtct actttgatcg ttccagaagt cataggctgg
     1741 actcctgtta aagttttcag caatgttgac ttaccggctc cgcttggcgc gacaatcgat
     1801 gtaaaggtat ctttagggat agtgaaatgg atgtcttcta atattttcag gttttcaatg
     1861 actacattca agtggctgat ttggattgac atatctatca ctcctatttt ataaactgat
     1921 tagtgaatag ttcttgcgaa ggtacatctt gcttgatcaa tccgttttcc tgcataaaag
     1981 ctgtataatt gcgccaaact ttttcttcca tcaatcccca attctcagga ttatccgtat
     2041 aattttttga caagaatgct tgtgattctt ctaaaaacgt ccgatcattt tcttttgcat
     2101 atttttgcaa cagtttagca ctgtcatttg gatccttaat agcttcctga tagccttttt
     2161 tcgtggcatc cataaaagac tgtaccaatt ctggatcact tttgatcagt tgatcattcg
     2221 taataattac cggagtatag taatctaacc gttcatctaa ttctttcaat gggatatagt
     2281 ttagttcaat acccgcttct tttgctttga tcatatccca accttcaaag taccattgga
     2341 tatctgagga ttttcctaag ctttctggcc cttctccatt gcttcctacc attgtcagtt
     2401 ttgaaaagtc cccgccgtct ttttccatca cagcttttaa gacagcttct tcacttggac
     2461 tttgccaacc tgcatatgtt tttccttcaa aatcttttgg tgaatggatg ttactgtctg
     2521 atagggtagc gaatccagaa gtattatgtt tgatcactgt agcaattgct ttgactggta
     2581 tattctgtcc atctgcgtga gcataagtga tatcttcttg ataacttaca ccaaattgtg
     2641 ctttgtccgc acctactaga ccaatacttg tcgaattatc tcctggttcg atgatttgga
     2701 catttaaacc agcctcttta taatagcctt tttcttttgc taggtagatg ccagtatgat
     2761 tagtattcgg tacataatcc aaaacaagtg tcactttttt caaatccttt gtttcttgtt
     2821 tgctacttgt ttcttttgca gtgccacaag cggataaaag caacagtagc ggtaataaaa
     2881 gccataattt tttcatttga tccccttctc ttaaaaaata taaagcatac gataataccc
     2941 ttttttcaat aatgaacaag cgccattcag caataaactc aatagaatga cacaaatgat
     3001 cgcagcaaaa actttatcga tctggtagct gttttttacg cgtatcatgt aataccctaa
     3061 gcctgcttga gcacttagcc attctccaac gactgctccg ctgacacaat aagtagcagc
     3121 cacttttaaa ccggaaaaga agccggataa acccgctggt attttatata ttcgataaat
     3181 cttccctgta tctgccccca tcgttttcaa aaagatgatt tgctcttttg atactttcct
     3241 caatgtatcc gaaaaagaaa ctacgatcgg aaaatagctt atcaagacaa caaggatcac
     3301 ttttggaagc ataccgaaac caaaccatag ggtaagtaat ggccctaaca ccatgattgg
     3361 caacatttgt gaaatcacta gtaacggata aaaagacatt tctaaaaact tccaataatc
     3421 cattgccaag gcagtaataa aagaaagaac gctagctatt accaaaccaa gcactgcttc
     3481 atttaatgtc gtgacagaat gggaaagtaa tacttgtgca tctgccgcta atgcagaaaa
     3541 tacagcagca ggtccgggta aaataaaggc aggtattttc caaactatga caacaatctg
     3601 ccaaataatt aaaatgaatg ccatactgac tgctggataa agatttttct tcattttgtt
     3661 acctcctttc ttctaatatg aataacaaaa aacgcttgaa atgggcacga catagtaacc
     3721 cgcttcaagc gtctgctatg tttctccctt caccagtatt aactgacagg ttcaatgggt
     3781 ctaagttcac aacttactct catgtcgtct acgacatccc cagaaacagg tattcatttt
     3841 ttaaagtgta gcacaagaag gaaaaagcaa caagcgcttt agttatcatg ctgattattt
     3901 caataaatag gagagatcac ttgccaatgt cggatacccc atgatatagc tatccaactc
     3961 ttttttagtc aatttttgat tgatgactag tgtcaaatca tcgatcaatt cgtctgcttg
     4021 ctcgctaatc actgcagcac caatcaaata attttgctgg tcaaaggtca attcagcctt
     4081 agcaactggt tcattgacac gatgataggt gaaccaactg gtaagatcca tctctaccac
     4141 ttgatctgac gaagaagcgt gactttttgt aacacctact tcagcaagtt taggactggc
     4201 gtagacgatc gtaggtataa tcggatattt gataggttcg cttgttgcat ccgttatccg
     4261 cttagctaca taatttcctt caaaagtggc gactggtgtc aatttggggg ggttccttga
     4321 aacaatatct ccacacgcaa aaatttttgg attgctcgtt tgcagataat cattgactgc
     4381 aattccgtgt ttatcaaaga cgacattcgc ttgctcaagt gctaaagatt ctgtattcgg
     4441 ctgtctccca gtcgcacaaa aaatcatatc tgctactaat tccgtctctt ttccgactaa
     4501 acgatagcga gtaccttctg aaatgatctt ttgggtttca acaccaaaag caaactgaat
     4561 gccagatgct tccatttgat ggacggcttc ctctaccaaa gacgcctcaa attcttttaa
     4621 tggccgttga ttatgatgga caatggttac tttgctccct gcagcattgg caatcgtagc
     4681 tagctcaaaa gcaatataac caccaccgat aaaaatgatt tctttaggca gtacaggcaa
     4741 tgataaaaag tctgcactag ttttcaagta ttcctttccc tccactggta agatcgtagg
     4801 tctttgcccg gttgccaaaa caaagtaatc cgcatggaag acttcttcgt tgacttcaat
     4861 agatgaatca tccaaaaaac gagcggttcc tgaaagatga tcgatttcag cttctgctaa
     4921 ttgttttttt cggctttctg ggactggatc cgtaaatgtt cgtttgaatt tttgaagttc
     4981 ttcccagttg gcagttggga tctcgttaaa accttttcca ctcaattgtt ttacccgatt
     5041 acgtgcctct actgcactta acaagacttt tttaggatca catccacggt taggacaagt
     5101 cccgccccat agatcttctt cgaccactag tactgtttta cctgcttctt tcaatccata
     5161 agcagcactt aagccgctca cacctgaacc gatgacgatt gcatcatatg ttttcatttc
     5221 cttcctcctc tcgacttaaa aaagcaaaga tttctttact tgtcagcgac ccaatacttc
     5281 tttgcttttc tactatcaca atgcttggat acaccgaaag aagcgaatat acttctttca
     5341 taggcgtatc aaagcaaact tgttgacgag cattttctgg tatttcattt aagaaatatc
     5401 cattgacgac taaatcttct actcgccact ctttcgtctg tttcggttca ttaaagaaat
     5461 gccgaacgta gtcgttttta ggattcatca ataactgctc tggtgtgtca cattggataa
     5521 tttctccatc cttcataaat gcaatacgat cacctaactt gattgcttct tccatattgt
     5581 gcgtaacgaa aacgatggtc gtgcccaatt cttcgtgtaa ggacaaaacc aattcttgta
     5641 atgagtttct tgaaatcgga tctaatgcgc taaatggctc gtccatcaaa atcacatctg
     5701 ggcttgcagc aatagctcgg atgatcccga tccgttgctg ttctcctcca gacaactctc
     5761 taggcatacg atctcgataa atatcaggag ataagccaac tttttgaaga agttcatcta
     5821 cacggtctgc tcttttctgc ttttcccaac ctaacatttc agggatgact tcaatatttt
     5881 gcttgactgt catggtcggg aacaaagcga tttgctgcag cacatatccc atattccacc
     5941 gcattttctg cagattatat tcatttaacg attttccttt gaagtagatg tctcctgctg
     6001 atggtttaga taatccattg atcattttca aagtagttgt ttttccacta ccggaaggac
     6061 caaccaaaac aaagatttct ccttttttga ttgccagatt taggtcatcg atgacatact
     6121 ttctatcata ctttttttgc acatgtttga actcgattaa tttagtcact gatcttcctc
     6181 ctttactaat ccttcatttt tcaggaagat tcgtgctact tctgtcggct ttttcttttc
     6241 gacattgact tggtaattca tatcaatcat ttgatcctct gttatttttc cgcttaattt
     6301 attcagtact ttaacgattt caggatgttc tttagcaaaa tcttttttca tcagcggtgc
     6361 gccttgataa gctgggaata accctcgatc atcttctaga gtcactagat cgtactcctt
     6421 gagctggcta tctgtggaat aggcatccac aatattgaca tctccattat tgattgcttg
     6481 gtaacgcaaa cttggctcca tgctttgtac acttgaaaaa ttcaagccat atgcttcttg
     6541 gattccttta tatccatctg aacgatcaat aaattccagt gtgaatcccg ctttgatctg
     6601 atcagagata gctgccaaat cggaaatctt tttaagttga tgttcgttcg caaaagatct
     6661 cttgactgcc aaggcatacg tattttggta agccattggt tttaataatg tcatatcgaa
     6721 ttgcttattc aataattctt ctgcttcgtc atatgttttt tcttttgtca aatcagcact
     6781 tttcattgct tcaggtacct tcaccaagct ttctaggaca gtacctgtga actcaggata
     6841 gatatcgatt tgaccttgat ccagtgcatt gaacaaaaaa ctcgtcttgc caaaattcgg
     6901 ttttaattca acttctgttt ttgtgttgtc ttcaatcaat tctttataca tttggatcag
     6961 gatttcaggt tccgctccta attttccagc aatcgtgatg gtttcatttt taaacaaggc
     7021 agactgatat aaagaaacgc cgccaaataa acacaccact gctgctaaag taatgatgga
     7081 atatcgaggt ttcttatgct gcaaccagcg aatcagtccg ctgaatataa ttgcaagcaa
     7141 ggcagaactg atcgcaccaa tcaatgtcaa aacaggtgta tttcggtcaa tacctaacaa
     7201 aataaatgtc cctaatccac ctgctccgat caatgctgcc aaagtagccg taccgatgat
     7261 taaaactaag gcagttcgga tacctgagat aatgacaggt aatgcgatgg gaagctctac
     7321 tttcagcaag cgtctcattc tggacatacc aaatgctacc gctgcttctt caatagacgg
     7381 gtcaatttca gctagaccaa tatacgtgtt ttggaaaatc ggaagcaaag cgtaaataac
     7441 aagtgcaatc aatgctggaa cagttccgat ccctacaaat gggataagta aacctaataa
     7501 ggcaagtgaa ggaatcgttt ggagcacacc cgtgatctgc aataagactt ctgccatttt
     7561 tttatgattg gctgcccaaa tcgctaaagg aatagcaatc agtgctgcaa tcagcaaaga
     7621 aatgagagaa atggacagat gttgaaatgc agcttccagc aactcgcctt ttctttcact
     7681 taatgtttgt ataaaattat tcatgcgacc ttcctttctg ttattcttta agtataaaca
     7741 tttctttcct ttttcccaac taacttgtct tgccttaacc ttacagcacg aacaaaaaaa
     7801 aagaaaaaaa tacctctaaa tatgctgaca aaaaagaatc caagcaacaa agtcggatca
     7861 actttttggt tctcgttttt tcactacgaa taccataaaa atctatacga aattgtcact
     7921 tggaatcagc tatatctttt ttacacacac aacttttatt ttaataaaaa gaaacagcca
     7981 ataaagtaga aatctcgtgg gggagaacac ctttattggc ctgttcaacg aatattatac
     8041 tgtatcatga cacttttttg ccaaaaatgt aaaaaacggt tgttttgaca tcataaacgt
     8101 cttgttttct tatttttact tatatcacca ctttattttc tatctctttc actccataaa
     8161 gcggaatgag ttcttctttt gactgataat aaacagcttt ctcacggttc ttcatcaaaa
     8221 aaagaaagat gtctttcata gcaagtggtg ctttgccgtg ttcaaataaa aagataaatt
     8281 gatttgcttt atttatctgg accattgtca caggcaccag tttttgttct tgagccaaaa
     8341 aaactccttg atactctgtt tttttgggtg attttgtaag aattgtcaat aagtctgctg
     8401 ctcgcatttt tccactcctt atttgataaa taaaaagaaa cagccaaaaa taattttttt
     8461 tcattttcct cttgaagtaa gagtataagt cagtataata aagaagttgc tgaaaatttt
     8521 caaaagaaaa gaggctagaa atgaaaaaat taaatttatt tacagaattg tgcggaatca
     8581 ttttaggcgc aggaatctac ggattagctg tgacaggaat caatattcca tctaagctgg
     8641 cagatggtgg ggttactggt attgctttgc tcttgcataa tctttttgga ttcgctcctt
     8701 ctgtcacttc actgcttttt aatttacctt tattgcttat ctcattgttt ctttttggaa
     8761 aacacgcttt tctccggacg atcgtcggaa catttgcgct agttttcttt ttacatttat
     8821 gggagagcct tcatatacat tttgctgtag atagtctact gatcaatagt ttgatgacag
     8881 gtattctttc tggcattggt tgcggtctcg tctttcgatt cggcggaagc acaggcggaa
     8941 cagatatcat ttatcaagcc attgaaaaat attttcatat taagattggc aaaagtcttt
     9001 tcttgattac ttttggtatt ttagttgtct ccttgcttta tttggatctc acacattttc
     9061 tgtatacatt acttagctgt tctattctat cttatacatt gaataaagtg aaatatctgg
     9121 aaattggatc tgttttgccc caattggaag caaaacagac tacagaaaca tttgaaccac
     9181 ttgaccctct tgaacagtta gagcactgat tcttattttt cactacttta tttacagaaa
     9241 tatcattatg taaactaaaa tgatattatt cagtaaaatc ttctttataa aaaaataaac
     9301 tatttttgca aacgatctgc gaaaatagtt tgttttttta ttttgccatt attttcttac
     9361 ttattgggag aaaaaattcg cttaagctca aaaaaatctg aggatacgat ataaacttcc
     9421 ggatagagta taaaataagg aaacgccgca gcgtttcctt tccaactgta gccgaatata
     9481 aatttgtata tcacttattt aaaatagcta ttttctccca aagagtttcc ttgatcatcg
     9541 atcaatcctt gtaatgagcg ttctaaaata ccatggcttt ttttcgattt tttttcttct
     9601 gactgctttg tttcctctaa catttttgtt cgattgaatg ttcgtacaga cggctcacca
     9661 tttctttttt cttgatacgg cgtcggttca gtatcgaaca acagataaga gtcatccgtt
     9721 tttttcatcg attcgattaa atgatcctca gaaattttgc tttctctagg gtctgggata
     9781 atcgatgcgg gtacatattt aggaacaaaa taagaacgct cccgcacctt cgtgtcaaca
     9841 gatgcgtttc gtgtagtatg cttggactct gtccttgttt cactttgtct gacagaacga
     9901 gaggaatcac caaaaagttt ttttcgtcct gtcgatgtga tttctgattg gtaatggccg
     9961 gtataatccg gtaattttcc tttatgcttt tccaaatttc ccttacgcgg agctgacttc
    10021 aatccatttg ttgcacgacg cttgcgacgg attttctcgg tgttcgtgtt cgtgaaatga
    10081 aattctttca tctgctcaaa cggggactga ttctgttcag tcaaaagatc ttcttgtccg
    10141 tcaaataata ctcgcttctt gtcgttggtt aattttacgc ctaactcatc atcgtacgca
    10201 ggaaaacgga aatgttttcg tctgatttct ttcattcaaa ccatccttct caaaaatgga
    10261 acttttctca ataatagcac agattcattg ttttcagtag caatgcgctg attattttaa
    10321 gaaaatagcg atgaatttca taaatatata tatagtaata agacttaatt cgttgtctct
    10381 ctgataacta gttcaggaaa aaaacgacga taaccttgac tcgccccttt ttcttctatt
    10441 ttttttaaca acatttctcc acatacttca cccatacgta taatatcttg cttgatcgtt
    10501 gtcaatttag gtgaactgat ttggtctaaa aataccccat caaatccaat cacaccaaat
    10561 tcttcgggca agtgtcctcc agcatttata atccctctta ctgctcctag tgctagccga
    10621 tctgaactac atacaaaaca agttttatct gtaaaatctg cccagttttc tgtcatatat
    10681 ctttctactt ctgtcgaatg atttggaaac cgcaagattt tactaggaag atcaacttcc
    10741 ttcatcacag ataaataacc agtttccctt gaaatttcaa aaggctcgtc cacttcgata
    10801 ccgatataaa taatcgtttg ataatctctt tctaaggcat attgcgttgc ttttgctgta
    10861 ccatattcat tatcgctgtc tacataatca tatccttcag aattttcccc aaacaagaca
    10921 actggttttt ccaaacgatc gatccaatcg aagtcttttt ttctgacacc tgtgatgatg
    10981 tatccatcac aagaaccgac gtcgaaggca tcatttgtaa ctaattggag agaataatgc
    11041 gctttaccga tccgtttagc gattcccatc agcaaattca tgtaataggg ctcagttgtg
    11101 tcgatttctt ccagtataaa taatttgatg atctgcgacc gattcgtgac aagtgctttt
    11161 gcagcaatat ttggacggta atccagttca gccattgctg agaaaactaa ctctttcaat
    11221 tcgtcagtca cctgttccgg atgattgatg actcgagaga ccgtcatttt tgaaacattg
    11281 gcacgttttg caacatctgc taaagtgggc atgctctctt cctttctaac atgttgtcat
    11341 tcttactatc aattatacca aattttccta acagagttta ttatagccca aaataaaaaa
    11401 cggaaaatcc tctatcgtca tgagtgattt tccgtttcaa ttatttatac ttttttatca
    11461 aattttttgc taaaaaagtg gaagcttctt ccattagtgg tatttgtacc atatgtcgct
    11521 gtgtttttga ggaacgaaaa acaatttctt ttccgtaaga cttatgccga tttttttcta
    11581 caaatcgttc cgtttgtata taagggattt tttcgtcagc ttgtccatgc caaaagaaca
    11641 gaggacgtcc agctaacttt tccggctgca atgacaaatc atagctctta acccatgaaa
    11701 tcaaatcaaa atagtctttt ggtacgacat aattatattc cgatccgcgc cttacgattt
    11761 cttttccata ttccaaaggt gcaggggaac ccatcaaaca cacgcccgct actatatgag
    11821 gatgtttagc caacaaggcg catgttgtca ttccccccat cgaaaccccg ccaactgcaa
    11881 gctgatcatg tagaagacct cttttttcta aatgcttgat aagtgtgtca aattcaaaca
    11941 gatttccgta gatactatcc caaaatgtat aggatggaat agaagaaacc ggctgtttgc
    12001 gctccccatg attcatcgca tctggcagga tcacacgaat gccctgctgc gcaatttttc
    12061 ttccttgcgt caaaactaac tccttacttg tctgccatcc gtgataatag atgacaacgg
    12121 gaatacgttc ctctcttaat tctttcagaa caacttctaa cactggaata tgatggacag
    12181 aacgtttcaa tataattgga ttcaattgtt actcacctat tttcattaaa tttcctgatc
    12241 gccatagcaa ccatgctcca acagttgtct ggaacaggtt cagtgtacca aataatataa
    12301 atgcaggact gaatggctcg ggaaataagc acagagaaca aagtcccacc actcctaatg
    12361 ctagcgaaag gagtggataa atagaaaaat tcaaaaaact ggcaacgcta ccgaaaatat
    12421 taccaataaa cagtatcaaa aagaaaaaaa cgcttaaaat taaaccatct gtcagcgaca
    12481 tctgaaaaac aatgttctct acctcaattg gctgttgaat cgaatagaca cctaagtata
    12541 tactgagaag gagacttagc acgtggctgg cacaaaacac acgattgacc gttttcattt
    12601 taatcaccta acctatcttt ataattctat tataatcatt ttatcatttt ttgtatgtat
    12661 aaagtttcaa tttttcttca cttacgattt tttttgatat tgttgttata taaatgaaag
    12721 gagttttaca aatgattgat ccaaaaatgt tggggatgat cttcctcatt aattttgctt
    12781 atatcactct gaacacgtta cgtttcatgt tgacaatgaa aggctatcga ctgattgctc
    12841 cacttgtcag tatggtcgag atcacgattt atatcgtcgg cttatccctt gttttagatc
    12901 gtttagataa tccactgaat ttatttgtct atgcgttagg ttacgcagta ggtatcagtg
    12961 tcggaatttt gattgaagac aaattggcat taggatacat catggtcaca acgattttgc
    13021 cagcaaatag cgcagaagat aaaagtttgc cgggtatact gagagaacac ggttatggtg
    13081 tgacacagac ttctgcaatg gggctggaag gtgagcggct agttctcgaa atactttctc
    13141 ctagaaaaag cgaacgtgaa ctgtatcgcc tgatcaaaga aatcgaagag cgtgctttta
    13201 tcatttctta tgagccaaaa tatatttcag gtggtttctg gactaaaaaa gtgagaaaac
    13261 gacaaggaaa ataactcaca aacttaaaaa ctgtctaata tctaaattaa attttaaatg
    13321 ttagacagtt tttatttatt attttgatta aaaaacatcg
//
LOCUS       DAFKHN010000065        13345 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFKHN010000065 DAFKHN010000000
VERSION     DAFKHN010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.065"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..190)
                     /locus_tag="LY912_002061"
     CDS             complement(<1..190)
                     /locus_tag="LY912_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBM6955722.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKY"
     gene            complement(187..840)
                     /locus_tag="LY912_002062"
     CDS             complement(187..840)
                     /locus_tag="LY912_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6955723.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1128..1648
                     /locus_tag="LY912_002063"
                     /pseudo
     CDS             1128..1648
                     /locus_tag="LY912_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1550..2266)
                     /locus_tag="LY912_002064"
     CDS             complement(1550..2266)
                     /locus_tag="LY912_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBM6955724.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(2390..2575)
                     /locus_tag="LY912_002065"
     CDS             complement(2390..2575)
                     /locus_tag="LY912_002065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955725.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            2802..4075
                     /locus_tag="LY912_002066"
                     /pseudo
     CDS             2802..4075
                     /locus_tag="LY912_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4182..5213)
                     /locus_tag="LY912_002067"
     CDS             complement(4182..5213)
                     /locus_tag="LY912_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955726.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(5220..6050)
                     /locus_tag="LY912_002068"
     CDS             complement(5220..6050)
                     /locus_tag="LY912_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955727.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(6047..6862)
                     /locus_tag="LY912_002069"
     CDS             complement(6047..6862)
                     /locus_tag="LY912_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBM6955728.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(6859..7683)
                     /locus_tag="LY912_002070"
     CDS             complement(6859..7683)
                     /locus_tag="LY912_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBM6955729.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(7673..8773)
                     /locus_tag="LY912_002071"
     CDS             complement(7673..8773)
                     /locus_tag="LY912_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBM6955730.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            8951..9736
                     /locus_tag="LY912_002072"
     CDS             8951..9736
                     /locus_tag="LY912_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBM6955731.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            9769..10152
                     /locus_tag="LY912_002073"
     CDS             9769..10152
                     /locus_tag="LY912_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBM6955732.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            10228..10359
                     /locus_tag="LY912_002074"
     CDS             10228..10359
                     /locus_tag="LY912_002074"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBM6955733.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            10328..10564
                     /locus_tag="LY912_002075"
     CDS             10328..10564
                     /locus_tag="LY912_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBM6955734.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(10642..11613)
                     /locus_tag="LY912_002076"
     CDS             complement(10642..11613)
                     /locus_tag="LY912_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBM6955735.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            12247..>13345
                     /locus_tag="LY912_002077"
     CDS             12247..>13345
                     /locus_tag="LY912_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HBM6955736.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPPFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGEREKQFAYSVHTSCDDNGFILSTIITPRNIHDSQVAFQLVKQSKRLFPEIN
                     CVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGKKELLSKNEFLYDEYFDCYICPQDQ
                     MLAFSTVTREGYREYKSNPKECVNCPLLNQCT"
BASE COUNT         4028 a         2976 c         2449 g         3892 t
ORIGIN      
        1 tatattttat ttcttttcca ttcatattac tagaaatttc atttgccata ttatgaatct
       61 tttcttttct cgtctccaaa tatgttttag gaaagataaa aaaaattaat gaatgaacta
      121 atataattat tattccaaga acagaaaata tttgtatgaa catttttgga aatatcttta
      181 attttttcat tttctctcca atttatatcc tacatttctt atagtagtta tacagtctaa
      241 ttgtaatttt tttctaagtt cttttatata tacatctatt actcgatcat aaggagtttc
      301 ttcgctatct ttccatacat aatcaataat ttgcattctt gttaacactt gtccattatt
      361 atccaataaa cattttaata cttctagttc ttttgcattt acatctattt cttcaccatt
      421 tattttagct gtatagctat taaaattaac cgatagatcc ttatattcaa acttctctaa
      481 atgtccataa ttcttcttaa ttaaagaatc tattctagct tttaagaccg gcaatgaaaa
      541 tggcttttct acatatccgt ctactaaatt agtaaatgca tcaattttat attcttcatc
      601 actaaatgca gtcaagatta gaattggtaa attgcttttc tttctaattt ctttcaacac
      661 ttctaaacca tttataaaag gtatctgaat gtctaagata accaaattta tatcgctatt
      721 aaattttgac aaggcttctc ttccatcttt agcttgaata acagtatatc caaattctga
      781 aagatattca cttattccct ctcttatcat attatcatct tcaacagtta atattttcat
      841 atatacctcc acttaagcct atacactaga tattatacag catattatgg ctctataata
      901 tctagtgttg gtgacgcctt ctgttgccaa tactttttct tttttttaat aaatgcaaac
      961 agacaccttg aaatccttta gaaaaaaggc ttctataata ttttgtgttg ttggaaaatc
     1021 gaaggcgatt ttctactaac actttttctt cgtttcaact caaaaagaga ctcacttttg
     1081 gtaaaattta gtcgaccaaa acatcaccct accaaaggag tcgctctatg gataatcata
     1141 ctagaaaatt actcggatta acagataaac atttattttt tgatgaagaa tggctgattg
     1201 aaaaagaata taaaggcgtt caagcgcagt ttattaaagg gagattggat gactcacctt
     1261 cccattgtga acactgtgga tcgattcgta ttatccgcaa cggttcctat acgacacgta
     1321 ctcagatgtt gaaagtcaaa gaaaagttga ctattttaga attaaaacgt acccgttttc
     1381 tatgctatga ttgtgggcag accttttctg cgaaaacgga cttagttgat gaacatcatc
     1441 aactaacaaa ggaactgaag caggcgattc tcatagaact gtacgaaaat caatcacgta
     1501 atctgaaaat cagaagaagt accgtcggct caagcgatat tggaaactct tactcaaaga
     1561 ttccacgaca ttggagccgc tcaaacggca ttatcatcga ctgtttaaac gaccaattag
     1621 tcaaacagaa atcgtcgatg aaccgttgtg cacaatggtg tcctgaacgt acagcgacac
     1681 cttccatatc cagagcagtc gccacatcac ggggatggat gccatccaaa ttaaaagcaa
     1741 ccacgccagt atgatgttca ggatcttgcg gtccgtaaat ggtgataccg ccgatcgctt
     1801 gtaatttagg taaaacgtag gcaaccagtt cttgctcata acgatgaata ttctccatac
     1861 caatctcatt caagtaatcg attgctcctg caatgttcgg agtaccagct tcaaatttcc
     1921 atggcagctc tttccatgaa ctatcgtaaa gattgacaaa atctatcatt tcaccgccga
     1981 attcgactgg ctccatttgt tctaacaatt gacgtttgcc atataataca ccgattcctg
     2041 tcggcccgca cattttatgc ccgctaaagg cgaaaaaatc tgcatccaac gcttgtacat
     2101 caactgtcat atgcggtgct gcttgggcac cgactggact atcctcaact acaacagcct
     2161 gttcaaccct cagccgtttc aagcacaaca aataaccttc tggatctggt ttgccgacct
     2221 gaagatcatc gatcgtcaca aaggaatcaa ttttttcctt aatcatcgga tgtgcttcaa
     2281 aaaaatagtc tagctcccgc agttcagaat tgagactact ccgattttcc agtgctgctg
     2341 atccgctgct caaaatgttc agcatccact ggtctcccaa ccgcttgact tatcccttca
     2401 taaaaggaca gttctgctgc cgtcccaaca ccttgttgat agtctgcaaa aggaatttta
     2461 tagccgaact gctccagtaa ataggcttca gtaaatagtg atgaatactc tcgtaaaaca
     2521 tccattcact gtcaatcatc gtcccatcaa aatcaaaaat aagtgctttg gtcatcttct
     2581 ttccccctta cccaaaacaa gcaaaagctg tgtcctgctc tctctacagt atcagcataa
     2641 aaactgccgt ctgaaaagtc aaaggtgaaa gaaatgtggc gctataattt ctaggactga
     2701 tagtaaatca ttctatcagt ccttttgagc ataaaaaaac aaaacataca gaagctccgt
     2761 tagaattgaa tcaccacaac acaatcaaag gagcgttctg tatgcctgat cttcatctta
     2821 tcaaactatt actaggaatc aaagatggaa acattcaaat cactcatgtc gagaagaaaa
     2881 aaatacattc aatcaacagt atcgttgttt ctgccacgct cattaaaacg attcagccct
     2941 gtcctcagtg taaacaggtg aatcaacatg ggctgatcgt taagaacgga aagaaaaaat
     3001 cgctggtcct tctcaataag tgtgcgaatc aacggactta tcttgctttg gcaaagcaac
     3061 ggtacctctg tcgtggctgt cacacctatt ttacggcgaa tacctacatt gttgaaaaaa
     3121 actgttttat cgccaaacaa gtacattata aaatattgga ggaattgact gaaaaacaag
     3181 caatgacgac gatttctaaa cattgcggcg tttcttggtc aaccgtttcg cgaacactcg
     3241 cttctctgct ccccatgaca aacgtgaaaa taaattggtt gcctcgctgt tcattggtag
     3301 atgaatttcg ttcattgaaa aatcaagtcg gtccctattc tttttcttgt atggatggcg
     3361 atactgggaa attactggat attcttcctt cacgtaagaa gaaagatctc atttcttatt
     3421 ttatgcaatt tgaacgacgt gcacgtttaa acgtaaaaat actcgtaaca gatatgaacg
     3481 cctcttatgc tttgctgata aaagagtgct ttcctcatgc caaactcgtt gtggatcgct
     3541 ttcacatcgt caagcacctc attcgcagtt ttaaggatat ttgactatga gtcatgaaaa
     3601 gcttcgaccg aaacgatcca atacaagcca aacactatcg acaagtgaag gctttatctc
     3661 gacttctgat caaacgacag gacacgcttg tttatgataa atggacaaaa tggcgtaatt
     3721 ttggttgggc ctatttaacc gaaagtgaag tcgtagaacg tctactttct acttctgatg
     3781 aactacgaat agcttatgct tactatcaag aaattcttca agctttttat gacaaagaag
     3841 cggacatctt ctttcagctt gtaaaaacaa tgcccaagtc ggttccaaga gaactgcatc
     3901 atataaaaaa agcgtttata aactatgaat ccggcattcg tttagcctta gagttgcctt
     3961 actcaaatgg caaaatagaa aatctgcata cccacatcaa agcattgaaa cgaatagctt
     4021 acgggttagg atgagaacca gaattttctt aatcaatcat ctgatcactt attaaacata
     4081 aaaaaacatc taaagcagaa aatcaattct accttagatg ttcttatatc actctatcag
     4141 tcctatttga caaagagcca gaaatgtttg ccgactatac actagctttg ttgtgcaaaa
     4201 tgctgagtat caatttccac agggattgct agaatatctt tcagctgaat gtataaggca
     4261 tcgctaattt tctcttcccg atcgttcaac cgatccacta aaatttcttt gccctccagc
     4321 gtttgaaaaa cataccgttg aatgttgcct aaaataaatg attccttcca tagaaccgga
     4381 atcttaaccc cctgaggaac cggttcaaat tgaatcagct ccggtcttaa ataataaatg
     4441 cagcgattgc ccttagcgga aaactcgtgg gtatactgat tcagctcata ccattcgaaa
     4501 cgattatagt tgccgataaa ttccgcaaca aatcggctct gaggattctg atacaattcc
     4561 ttcgaggtgg aaacctgagc cacccgccca gcttccatca caaaaatccg atcactgatt
     4621 cgcatcgcct cttcttggtc atgagtcaca aaaatcatcg tcatccctag cgattgctgg
     4681 atagcgcgca aatcccgctg cagctgtttt ctaattcggg catccaaagc acttaatggc
     4741 tcatccagca gcaggacttt cggttcagtg accaatgagc gagccagtgc cacccgttgt
     4801 cgttgaccgc cagaaagaaa ctggacattt ttatctgcct gctccgtcat atccaccaat
     4861 gatagcatct caaaaacctt ttcctgaatc acctcaggac tcagcttctt taccttcaaa
     4921 ccaaaggcta cattttcaaa aacagtcata gttggaaaca atgcatactg ttgaaaaaca
     4981 aagccgatat tgcgatcctt cgtaggctta tcggcaatat tctcattgtc cagcacaatc
     5041 tcaccgctct ttggttgttc caatcccgtg atacagcgca gcaacgtaga ctttccgcac
     5101 ccgctgggac ctagtaaagt aaccagctca cccttttcaa tctgaatttc atcaatagct
     5161 aaaatctgtt tttcatcaaa aaacagattg agatcatgta tttctaaaaa cattttccgt
     5221 cacaactcct ttaagggctt ctttttcgac tgcttctctt ccctcgtctg cttaagggac
     5281 agctgttgct tttgtcgata agtcagcata aaggtagtta aagcaattcc caccataaac
     5341 agcaaataca aaaccatcac agcgctagcc aaatggccgt tttcgttcat ccgccgcagc
     5401 atatagatgc gtaccgtctg aaatcgaccg ccaatcaaca ggttcgtcag catgtactcc
     5461 ccaaaaaccg aagaaaaaat catcagagaa actagggtca caccgatacg gatgtttgga
     5521 aacagcacct ggataataat cgtagacatc ggggcgccca aggtttctgc tgcatccact
     5581 aattccttca gattaattaa gcgcatctgg ttgttaagac taagatagac aatcggcaac
     5641 gccgtaataa acaatgcacc taccaacact acaaacattg ggataccagt ttcagcatac
     5701 gttcgaagca aagccgttac caaaatcact cctggtaaag catacggcag caggagcagc
     5761 ttttccagcc aacgattcaa acgagggaaa tacaaatgaa tccaaataat ggtgggaatc
     5821 atcaacaaca gaatcgtcac caagaccaca cctgctaata aaagtgagcg acccaccgca
     5881 gcaataaatt ccctgtccgt cagcagctgt tggaaccatt gcaaggtaaa atcactaggt
     5941 aaaagcgatt ttgaccattt agtggagctg gcatacaaaa tcgttccaat aatcggcagc
     6001 aagtaataca ggacaaagca gaacaaaatc ggttttatta actttttcac gtctgcacca
     6061 ccttgccttt cttttgaata atcaacattg ccgttaccag caggacacct aaagcgactg
     6121 ccaacgcact gcctaaatta ggcttggcga acacatctcc cgacactaaa gccgcaattc
     6181 gaatcgttaa aagatttaca ttactgctgg tcagggcata cgctgtttca taggtcccca
     6241 tgccattagc aaataagatg acaaaggtgc tggcaatcga tggtcgcaaa aaaggcaaag
     6301 ccaccttgaa ccaagcatac gctgatgaag cgcccagcaa ttgtgcggac tccagccatt
     6361 cctttttcac ttccttcatg ctgggataca aaaacaagac ccctaacgga atttggaaat
     6421 aggtatacgt gatggtcaat ccccaccaag aatacaaatt gaagtccgct agaaatggca
     6481 aaatcatttt cagcacacct acattcccca acaaaataat aaaagagaat gccagcggaa
     6541 tcccagcaaa attagctgcc aaattggaaa caaaggtgat tttctcctgc aatttagtcg
     6601 atagattcat taagcataaa cataaaataa acgtcccgat taacccaatc acactggagc
     6661 tgacagcaat cagtacgctg ttaacaaagg cctgtgtgta atatttgttg ctgaaaatat
     6721 cactgtaatt ggccaatgtc cactggttag ttaaatcact gtgcaagctg cacagaacca
     6781 taaaaagcag cggcagcagt aaaaatgcac agaagataaa ggaggcagga accagaacca
     6841 agcgtttttt catctctttc atcccctcat caattcttga atgtcctgca ttttctctga
     6901 cggtgcaatt cctaataacc agcaaaacaa tggagccgcc agcagctgtg gtacagtttg
     6961 ttccttcagc ttttggcgtt tatttgaaat caaataaaaa ggaacttcac gatgtgcagc
     7021 caagctgccg ccatgcagtc cgtgcgcatc catcccgtga tccgcagtca ccacgacttg
     7081 ataacctttt tgcagccatt caggaaggta aatagccaat aatctgtccg cctgattaac
     7141 cgctgctgca tattcatgag aatcggcggt aaatttgtga ccgacatcat caatattcat
     7201 cgaatgtacg accaaaaagt ctggctgata ctgattcact aaataatggg catccgcaaa
     7261 taaatgcgaa tcagggtaag tgtcctcact ataaaagatg ccatgctgaa tcagtcgctc
     7321 ctcctgatgc tggatgcgat caaccaaacg attatagggg gcttgattgt acaactcgct
     7381 gtaccagtgg taagcggcgg ctcctgtttt tccgccagct tccttaacta attcaaacag
     7441 cgaccactct ttggatcgct gagcatggta attactatag atgccatttt cataggctgg
     7501 aacgccggtc atcagtactt cgtataacgg acgtgaattg ctgggcagct cactttttac
     7561 cttcaataag cttgcttgct ggtgctcaac taaatgattc atgaacccaa gctgggcgac
     7621 ggctgtgtcg tagcgacagc cgtctagtat aactacaatc agtttgtcaa gtctactttg
     7681 cataggtcag tacctccgcc tgccaaagct ctggaagctc tacagaggtc ttgttccaag
     7741 cttcattgtc ttcaactggc accgccgctt cataagcatc ctccggcagt aatttttcag
     7801 ctacttcttt aggcagctct accttgcgaa taggtcgcgc atagcccttt gccaaattga
     7861 tttgcccttc atcagataaa atatattccc gtgctagctt tgccgcattg ggatgagggg
     7921 catttttatt gattaaggtt gtatacccgc taatgatgga gccgtctgtt ggcacagtta
     7981 cctcaaaacg ctcggagtca atttggtcac gataatttag tccattgaag tcccaaacaa
     8041 ctgccacatc gatttcacct ttttcaagat ttgctacgct ggcatcaacg gtggacaaac
     8101 ggcctttttc tgccattttt ttgtagtaat tcagacctgg ctgaatatcc ttttcgtcac
     8161 ctccgttggc aatcgccgca gccaatacag caaattgtgc ttggttggca atcgtcacat
     8221 cccccacgct aacttgatag tcaccctctt gcagctcctt ccagctagtc ggtgcttgct
     8281 tcacattctc tttatcggtg ataaaggaaa tggttcccgt atagcttaac aaccaatccc
     8341 catcatcatc ctttgcccaa tccggaattt cctcccaata gttggtctta taaggtaagg
     8401 ttaactcttt gctttcagcc aacggaccga agctgatacc gacatcacca atatcggcgg
     8461 ttccattttt tccttctgat tcaaacttag ccaattcttc tgcactggac atatccgtat
     8521 ccacgtgact taagccgtat tctttttcaa ggtcgttcca agtgcctacc caatttgccc
     8581 aagtatccgg cattcccaag ctggcaatct ctccttcttc cttggctttt tctataatcg
     8641 tatctaaaga gtcgtctgcc gcagccgatt gcttcgttgc ttcacctgag ccgcagcctg
     8701 tcagcaggat acttactgtt gctgcacaaa ataaaccgat agtcatgtta cgaatttttt
     8761 cattcatttt cattcattct tctccccttt cgataattcc attctaacaa agctttgtaa
     8821 tgagagaatc agtttcttga aaaggtttca tgaacaatgt aaaggttgta tatggtttgt
     8881 aaatttcgac gaattcccgt taaccttcta aagcttttgc ggtatgatag tagaaaaaag
     8941 gaggctccct atgcagtatt atgatcagca tctccacacg tatttttcct ttgattcaga
     9001 ggaaaaattt gaaaactatt tagcctatca gccggagttt ttcgtttcta cggatcactt
     9061 tgatttaaac aatccatcta ccggaaaaga tgacattccg gattatccag cctatataaa
     9121 caaactggac tctttaaaag aaacctattc caccaaattt ctgcgaggta tcgagattgg
     9181 cgttgttcca ggacaagaag agcggatcgt ggattacctc gctcagcatc cttatgattt
     9241 aaagctggta agtattcatc aaaatggccg ctttgattat atggacgatg tggttttaac
     9301 caaagatccc attcaaacta ccaaggaata ttttgatcag atgttgcagg tcttgacgga
     9361 ttttccagaa ggagatattt tgactcactt tgattatgga ttacgccgct tcaccttcac
     9421 agcggaagaa ttcgcggagc attttgaggc tcagctgcta acgattttca aaaaggttgt
     9481 tgaacgagaa ttggcgatgg agttaaatgc caagagcttc ttgaaatacg gcaacgaaga
     9541 cctttaccgt tatgccgttc ctttgtatca aagtgtcggc ggaaagctct ttaccttagg
     9601 ctcggatgct catgttgccg aagattatca gctgggcttt aaaaaaatga gtcagctgtt
     9661 ggcagactgt caggtagaaa agttgctagt cattcaagga aaagaacgcc gcctgacgcc
     9721 gctgccgatt ttgtgattcc tatataatag aagaaagtgg tgaaaaaaat gagcaacctg
     9781 tgggactaca atcaagaggc acccatccat tatttaattg cgcgacattg ggatgcgttg
     9841 aaaattgagg cggtttgccg atccttgtta gcagccgttc caaaacaaca actggaaaat
     9901 tttttggtgg ctgacagctt gcagcgggaa aaagttcagg cttattttgc agcctttaaa
     9961 gatcagcctt tggaatattt gcatgcgcag tttcatcttt tttatcaagt agccgcccca
    10021 gatgactaca acgatttacg aggacagctg caattgacct ttcaagcgga tgaaaccgcc
    10081 tataccgttt tattgggaat ggctcgcctt ggtgatcagg cgaaggtcga gtggcggatt
    10141 ttcgatattt gatggcagga tcaaggcgtt tcagttgcaa accttcctct ctttcaatta
    10201 gaaaaaccgc agcaggaaga agtttgtgtg ctggtcaccg atgctggtga aattcgtctc
    10261 cgcttatttc ctgaccaagc tcccctggct gtagccaact ggcgctccct agctgagcaa
    10321 ggcgtttatg acaacacacc tttcggctcg tgtcattaag gaatttgtta ttcaaggtgg
    10381 cgctttggat ggttctggtg atgaagctgt ttccagctat gagggctttt tcgctgatga
    10441 agtgcatcgc ggactttatc attttaatgg cgccttggcc ttaggggacc acggccccca
    10501 caccaacggc aaccagtttt ttattgtgca aaacacaaag gcgcaggctg acctgctaat
    10561 gtaaagcaag catacttgga gcttggagga ctaccggagc tggatggtcg ttatactgtt
    10621 tttggacagg tataccaagg gttagaaatc gtagcagcga tcgcagctca gccgacaaac
    10681 agtgaagatg taccgattga gccagtgttc attcgacaaa ttaacttcga aaaaacatcg
    10741 taaaaagaca ctcactgact tcagcaaaag ctctattctt gagctggctg cagctagtga
    10801 gtgtctttca tttatccata agataaagct tggattcaat aaataaataa atgttttggt
    10861 taaagctgtg accagcaaat gaggaaccgt gcgagccagt tgatctgcca atgcaaacat
    10921 ttctttaggt gaaggcgctg gcgtgtctgc caacggatac tccagtccca atgcttggta
    10981 accgtgcata ccatagcagt ggtacggtag taattctaac ggtacgaacc gatcaagatc
    11041 tgccacaaaa caagcaatcg tcagcagctc ggtcaggttc atattgatac ctggaaccac
    11101 aggaactcga attcgcactt cgcagttagg atactcaatt aaaaagcgac gaatattctt
    11161 caaaatttgt tggttatcta agccggtcca ttgtttgtgg agcttgctgg taaacatttt
    11221 tacatccaca aacaatgtat ccacataggg agctaccttt tggatttcat tataagcacc
    11281 acaaaagctg gtttccagta cggtattgat tccaatgtat ttcgattttt gcaaaatttc
    11341 tttagcaaaa tccgcctgaa ccagtgcctc gcctccgcta atggtcactc cgccatccga
    11401 gtgaaagtaa aaaacagcat ccttctcaat ctcatccatt acctcttcag cggtcatggt
    11461 ctggccaaat cctttttcaa tctgcttgct ttgtgattcg ggaatcgaac accaggcaca
    11521 gcgtaatggg cagcccttta aataaacaac ggtccgtaaa ccagcaccat catgtagaga
    11581 accctgttct attcttaata ctgttccttc catatagatt tttgaattac acactagttt
    11641 aaactaaaac acacaaggaa aaacttacca tttaatcata aaattagctc atataaatat
    11701 actaggatgt aaaatagact ggtcaaaatc tggtcaaaaa agaggactaa tacaggtagt
    11761 cctctttttt gttattttaa tattctaaat cattttttat tggtttattc ccttattcga
    11821 tgtagactca aatcactata tcactagata tcaaacggcg tcatacggaa tcaaaaacat
    11881 caaatttgac ctgttaaatg gtcattgaat aacattcaaa atcaataaaa cggagtcaga
    11941 cacggagtca aaaacgctga gagtaaaaaa tatatacagc cttgtaggta aagtaccaca
    12001 gggctgtata ttttttattt cagattacct taaatgattc catttacttt ttatctcatt
    12061 ttttcctact agttagtatc aaatactctc ctattttctc aataaactat ttttggatac
    12121 atggtatctg aaacagctaa aaccttgtca ttacagcaaa aaatcacgtt atccagactg
    12181 tagacaaagt ccattttatg gatgatgtct acagtctttt cttttataat agatttatga
    12241 aaacgaatgc aaggagtgat agctatgatg tctaaaaaca atacgaatgg tagaaatcaa
    12301 tttgcgatgc ttacgattga tgatctagtt cctcaagatc atctcgttcg aaagattgat
    12361 gccgcgcttg attttgaatt tatttatcca atcgtcgaag ccacttactc cgatttaggt
    12421 cgcccaagta tcgatccagt gattctgatc aaattggtgt ttattcagta tttattcggt
    12481 atccgttcca tgcgacaaac cattaaggaa gtcgatacca atgtcgctta ccgctggttt
    12541 ttaggctact ccttcgagga gaaaatcccc cctttctcaa cttttggaaa gaattatgtt
    12601 cgccgattta gagaaacgac ggtgtttgag gatatttttg cctatatttt agaacaagca
    12661 gttaaagcag gttttgtaac agaggataat ttgtatctgg attctaccca catcaaagct
    12721 aacgccaata aacataagtt tacgaaagaa atgacccatg atgaagcgaa agcctatcag
    12781 gatgaattag aagatgagat caatcgtcaa cgaatagagg ctggaaaacg cccttttact
    12841 ttggacttag aaaaggaagt gaagctgaaa gaaagaaaaa taagtaaagc tgatccggaa
    12901 agcggctact acgtcaaagg cgaacgagaa aaacaatttg cttattctgt ccatacttca
    12961 tgcgacgaca atggatttat tcttagcaca atcatcactc ctagaaatat tcatgacagt
    13021 caagtcgcct ttcagctcgt caaacaatcg aagagacttt ttcctgaaat caattgtgtt
    13081 gtcgctgatg ctgggtataa gacacctaag tttgttcact ttttgactca tttgaacctt
    13141 cgaccttgtt tgccttattc aaggcccaaa gggaaaaagg agctattatc aaaaaatgag
    13201 tttctctatg acgagtattt tgattgttat atttgtccgc aagatcaaat gctcgctttt
    13261 tcaacggtta ctcgagaagg gtaccgagaa tacaaatcca atccaaaaga atgtgtgaac
    13321 tgtcctctgc taaaccaatg tacca
//
LOCUS       DAFKHN010000066        13307 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFKHN010000066 DAFKHN010000000
VERSION     DAFKHN010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.066"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(166..570)
                     /locus_tag="LY912_002078"
     CDS             complement(166..570)
                     /locus_tag="LY912_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6955737.1"
                     /translation="MSRQLVLISHGKFCEELKNSTEMIMGPQENIYTIPLLPEDGADT
                     YKERFLSVTAPLKDYVVLCDLLGGTPANTVSKLIMEGETIELYAGMNLPMVIEFINSQ
                     MIGAEPDFIGSGRESIVSVNQVIAGMGDDEEE"
     gene            complement(586..1395)
                     /locus_tag="LY912_002079"
     CDS             complement(586..1395)
                     /locus_tag="LY912_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBM6955738.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDDTPELKEMMKTHTQFFNTSNFFNTIITGIDLAIEEKEGVSSKETVSGMKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPVGILIWILAQVAVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKLLPAGIVGGVYWMLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            complement(1382..2272)
                     /locus_tag="LY912_002080"
     CDS             complement(1382..2272)
                     /locus_tag="LY912_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6955739.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDQHVETMNYKAIERNFLMGALPWALSRMVPVFLAL
                     AFGGGLVQNVVAVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHISYLILGFT
                     ITALLATVFSNVQLLGTSVASVVKDFPGTFNSLPMLAVALIGLALATISYKNDQKNDQ
                     HPVVSQQSQSDEGEIEDDEI"
     gene            complement(2285..2764)
                     /locus_tag="LY912_002081"
     CDS             complement(2285..2764)
                     /locus_tag="LY912_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HBM6955740.1"
                     /translation="MAIIGVRIDGRLIHGQVANLWTTKLNIGRIMVVDDEVATNAIEK
                     SGLKLATPAGVKLSILPIEKAAANILAGKYDSQRVLIVAKKPDRILALVEKGVPIKEL
                     NVGNMSQTDETRSITKSINVVDADVEVFKKLDQLGVHLIAQMVPNDKAEDFMSLLIK"
     gene            complement(2781..4547)
                     /locus_tag="LY912_002082"
     CDS             complement(2781..4547)
                     /locus_tag="LY912_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HBM6955741.1"
                     /translation="MTRFEIKEEFLLDGQPFKILSGAIHYFRVHPTNWERSLHNLKAL
                     GFNTVETYVPWNLHEKEEGTYDFSKILDLSHFLELAQSLGLYAIVRPAPYICAEWEFG
                     GLPAWLLTKECRIRSADPRFMKYVKRYYQTLLPKIVPHLVTHGGNVLMVQVENEYGSY
                     GEEKAYLRQVKKYLEEGGIDVPLFTSDGPWQATLRAGILIDDDVFTTGNFGSKAKENF
                     ADMAQFFEAHGKKWPLMCMEFWDGWFNRWKEPIIKRDPEELADAVKEALQIGSINLYM
                     FHGGTNFGFMNGCSARGAIDLPQVTSYDYDAPLDEQGNPTEKYFALKRMMAENFPEMQ
                     QMEPWIKETIVKKGINLKEKVSFFATLDTISKPIHSTYPQTMEELGQNTGYLLYRTTI
                     KKDAVNEKLRIIDGRDRVHVFLDEEKQAIQYQTEIGETIPLTLEKEDHQIDLLFENMG
                     RVNYGHKLLADTQRKGIRTGVMSDLHFITEWTQYCLPLETTEHIDFSKKWEAGQPAFY
                     RFEAELSEIGDTYLDLSEFGKGIVWVNGTNIGRFWEVGPILSLFVPEGLFRKGQNEIV
                     IFETEGRFSEVIDFVKEPIEKS"
     gene            complement(4593..5534)
                     /locus_tag="LY912_002083"
     CDS             complement(4593..5534)
                     /locus_tag="LY912_002083"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HBM6955742.1"
                     /translation="MITTVTMNPSIDIAYTLDELRIDQVNRVKTVNKTAGGKGLNVAR
                     VLHLLADDVLATGLVGGQHGAYIKEQLDQSGITHQFLPIKGETRDSIAILHGVNQTEL
                     LESGPVVTEEEQHKFTEHFARLMETTDIFTISGSLPQGFSKSYYAELLALTNKKGTRV
                     LLDTSGQTLLEVLEGKEKPFLIKPNLEELGELVHQTISSATSLDEIQSLLDHPLFEGI
                     NWIVLSLGAKGAIAKVGRHFYQVTIPKIAVVNPVGSGDSTIAGLAHALSKSYTIEETL
                     AFAMACGMANAQQEKTGWIDPVKVDYFRGEINVRKIR"
     gene            complement(5531..6526)
                     /gene="lacD"
                     /locus_tag="LY912_002084"
     CDS             complement(5531..6526)
                     /gene="lacD"
                     /locus_tag="LY912_002084"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBM6955743.1"
                     /translation="MNEEKIAAMKSLSTKEGIISALAIDQRGALKKMIKALGKEPTAQ
                     QITEFKELVSAELTPYASAILLDPEYGLPAAKARHQEAGLLLAYEKTGYDATTPGRLP
                     DLLADWSTLRLKEQTADAIKFLLYYDVDEDPEINHLKHVFIERLGSECAGEKRPFYLE
                     LVSYDAKTNDSTSLEYAKIKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVEGYSDG
                     EIAYSKKEAAAFFKEQSDATPLPFIFLSAGVSTALFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGREGAIEWLRTQGRQNIESLNKVINENATPWFDKVKEDSVTAK"
     gene            complement(6519..7712)
                     /locus_tag="LY912_002085"
     CDS             complement(6519..7712)
                     /locus_tag="LY912_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6955744.1"
                     /translation="MFELSKDKLKELGAEITTREIKQQPQLWKETAEILAQNQEKLAL
                     FFDQIKKAANGKRVRVIFTGAGTSQYVGDTAVPYLNEYGDNDHFIFHSFGTTDIVSSP
                     KEFLFPDEPTLLVSFARSGNSPESVATVKIANEQIKTLFHLTITCAKEGQLAKNAATD
                     ERNYLLLMPEKSNDAGFAMTGSFTCMLLSALWVFDQTAVEKKESYLQQLIRTGEDLIS
                     RDQEIQKLLPKSFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVIGFVNNQPYTRNYDLDILEEIKDDQITTSVIAIAQPGNIDFTGTSLLLE
                     ASISLPDAYLALPMIMTAQIIALDTSIKVANKPDTPSPTGTVNRVVKGVIIHEYVNKG
                     ETKDE"
     gene            complement(7730..8458)
                     /locus_tag="LY912_002086"
     CDS             complement(7730..8458)
                     /locus_tag="LY912_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6955745.1"
                     /translation="MESSSKGKSLYYQLVDVLKERIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELETQGYIYRRHGKGTYVSDLSDKSSDLAGAYSFTEEMRELGRVPNTV
                     ILEFKQMEANKKVAKNLNINLGETVFKLKRLRLADDEPLMVERSYLPAKLFIGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDADPLRIADGAPVLYLSRTTYNVKN
                     EIIEYTDSVARADQFHYKIRHVRK"
     gene            9296..9562
                     /locus_tag="LY912_002087"
                     /pseudo
     CDS             9296..9562
                     /locus_tag="LY912_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10945..12111)
                     /locus_tag="LY912_002088"
     CDS             complement(10945..12111)
                     /locus_tag="LY912_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBM6955746.1"
                     /translation="MKISVFGLGYVGLANSLLLAQKEQVKAYDIVEEKITMLQNGISP
                     IEDKEVHEFLKRDDLNVEFTSNFTDAVNFGDYLIIATPTDYDEKKNYFNTSTVEDVIE
                     KALAIRPDSTFIIKSTVPVGYANEIKAKFGTENIIFSPEFLREGKALYDNLYPSRIIV
                     GECSARGREIATMFQRNAFNKDASVLLTHSTEAEAIKLFSNTYLALRVAYFNELDTYA
                     EFRGLDSKQIIEGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLRANYEKVPSNIISAI
                     VDANTTRKDFIAGQILAKKPNVVGIYRLTMKAGSDNFRYSSIQGIMKRIKAKGIEVVV
                     YEPTLDEDEFYHSQVLKDINEFKNISDVIVSNRFEDILKDVEEKVYTRDIFGDN"
     gene            complement(12199..12483)
                     /locus_tag="LY912_002089"
     CDS             complement(12199..12483)
                     /locus_tag="LY912_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955747.1"
                     /translation="MSSVSESTSKIGRIKLGNNIFIGIYSIVFPGVSIGDNVIIRANT
                     LVNKDIPNNSVVAGSSCKVISTIEEHYEKNKNEFIKYRTSMILKQKNFFY"
     gene            complement(12713..>13307)
                     /locus_tag="LY912_002090"
     CDS             complement(12713..>13307)
                     /locus_tag="LY912_002090"
                     /inference="COORDINATES: protein motif:HMM:NF026018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HBM6955748.1"
                     /translation="ITSENDDFIERFVEKNTYIFKMYIRLATLSIPIICCAYSFITNP
                     DYKKSLVLVPILVIMACFSGMTTNIGNIFAVYNKTNQLLMISVVSGLLSVVGTYLLGY
                     SFGVIGVSFATLLGTLVLFGLRYYFGRKIAYYAFDWKRISLLLVLYSAIAFVCIHRGF
                     YFNLFLTIIFSAIFVFTYKQLIITYLKKFFRIKMAKR"
BASE COUNT         4002 a         2819 c         2081 g         4405 t
ORIGIN      
        1 ttcttcgatc gacccagatc atttctgatt ttatgacgat aaaagccaac gtactgtgaa
       61 atatagaaaa ctatatttcg cggtacgttg gcttttttat acacggcctc tttatacatc
      121 cgtatttata tccagttgta tcaccagtca agaagttgtg cttgattatt cttcttcatc
      181 gtctcccatg ccagcaatca cttggttcac tgaaacgata ctctcacgac ccgaaccaat
      241 aaaatctggt tctgctccaa tcatttgcga attgatgaat tcgatgacca tcggcaaatt
      301 catgccagca tatagttcga tcgtttcacc ttccatgatt agcttggaaa cggtatttgc
      361 aggtgtccca cccaacagat cgcaaagcac tacgtaatct ttcaatggtg ctgtaacgga
      421 gaggaatctt tctttatacg tgtccgcgcc atcttcaggc aataaaggga tcgtatagat
      481 attttcttgt ggtcccatga tcatttctgt actgtttttt agttcttcac aaaatttacc
      541 atgactaatc aagactagtt gtctactcat ctttccaatt ctcccttatt tcgaaatcac
      601 acctaatgca gataatgcta cacatacgat caatacgatg aatattgctc gagtaggtgt
      661 catatttttc ttacctaaca tccaataaac gccaccaacg attccagctg gtaaaagttt
      721 aggtaagatc atatcgatat agttttgcat attcaacgtt acatccccaa tcgttggtgc
      781 ccatgagaat ttaacattga tcatggttgc tactaacgct ccaaccatga aaactcctag
      841 taaagtagcc gcatctgtca atgcagtcaa gcgtgattgc atcgtggtaa ctagagaaat
      901 cccttctttg taggcaaatt ctagttgttt ccaacgaaag accatgacag cgacctgagc
      961 aaggatccag ataaggatac ctactggatt accatctgtt gccatatttg cggctaaagc
     1021 tccaaatatg gtcgggatca atgccgcaaa tacagaatca ccaattgcag cgaaggaacc
     1081 catcaatcct gctttcatcc cagaaacagt ttcctttgaa gagactcctt ctttttcttc
     1141 gatagcaaga tcgatcccag taatgatcgt gttaaagaaa ttagacgtat taaaaaattg
     1201 cgtatgtgtt ttcatcattt cttttaattc tggtgtatca tcaccataga tttttctaag
     1261 ttgtggcaag atagtataca gataacctga accttgcatt ctttcatagt tccaacctaa
     1321 ttggaaagta aacaaacttc tacgattgat ctgcttaaaa tcttctttgg tcaatttata
     1381 attagatttc gtcatcttcg atttccccct catcagattg tgattgctga cttactactg
     1441 gatgttggtc attcttttga tcattcttat aactgatcgt tgccagtgct agaccaatca
     1501 atgccacagc aagcatcggt aatgaattga atgttcctgg gaaatctttg accacgctag
     1561 ccacacttgt tcctaacaat tggacattcg agaacactgt tgctaataac gctgtgatcg
     1621 taaatcctaa aatcagataa gaaatgtgtt tctttactgg taggtagcgt agtaaaattg
     1681 caaacccaac tgctggtaag actgcccctg caacagataa gccatctcct agccatttta
     1741 ggtcgccgtt taaaacagcc acaacatttt ggactaagcc accaccgaat gctagggcca
     1801 agaatacagg aaccattctg gaaagtgccc aaggtaatgc ccccatcaag aagttccgtt
     1861 caattgcttt gtaattcatt gtttccacat gttgatcgat ccgatgtgca aaatacgtat
     1921 tcgcaaaacg tgccaaaata tctaattgga tcatcaaact tgctacagga accgcgatgg
     1981 ccgcaatcgc ttgttctggg ttcatcccta gagaaatgga gaaagctgtt gctaagatcg
     2041 ttccagagtt ggcatcgatt tttgatgcac caccaaatgt ccctacccct aaaacagtca
     2101 actgcatact tccaccaatg attaaacctg cttttaaatc acccattact aacccagcat
     2161 ataatcctgc aaaaactggg gcgctcattg aagaataaat ctgtaattca tctaaaattt
     2221 gataccctgc atataatgtt aataataata tctgccacca ttgaatatcc atgaatcatt
     2281 cctcctattt gattaaaaga ctcataaagt cttctgcttt gtcatttggc accatttgag
     2341 cgatcaaatg aacgccaagc tgatctaatt tcttgaagac ctctacatcc gcatctacga
     2401 cattgattga ttttgtgatg gaacgtgttt catctgtttg tgacatattg ccgacattta
     2461 attctttgat cggtacacct ttttctacta gcgctaagat acgatctggt tttttcgcta
     2521 cgatcagcac tcgttgagaa tcatatttac ctgctaaaat atttgcggct gctttttcaa
     2581 taggtaaaat acttaatttg actccagctg gcgttgccaa ctttaaccca cttttttcga
     2641 tcgcatttgt tgctacctca tcgtctacga ccatgatccg accaatattc aactttgtcg
     2701 tccaaagatt tgccacttgt ccatgtatca aacgtccatc aattcttact ccaataattg
     2761 ccatcatcca ttctcctttt ctaacttttt tctattggtt ctttgacaaa atctataact
     2821 tcactgaatc taccttctgt ttcaaagata acgatttcat tttgtccttt tctaaataaa
     2881 ccctcgggaa caaacagtga aagaattggt cctacttccc aaaaacgacc aatattcgtg
     2941 ccattcaccc aaacgatccc tttcccaaac tcactaaggt ccaaataagt atcaccgatt
     3001 tctgacagtt ccgcttcaaa gcggtaaaat gctggttgac ctgcttccca tttttttgaa
     3061 aaatcgatgt gttctgtagt ctctaaaggt aaacaatact gtgtccattc tgtgataaaa
     3121 tgaagatcgc tcatcactcc tgtacgtatt ccttttcttt gcgtatcagc tagcagcttg
     3181 tgtccatagt tgacccgtcc catattttca aataatagat caatttgatg gtcttctttc
     3241 tcaagtgtca atggaatggt ctcaccgatc tctgtttggt attgaatcgc ttgcttttct
     3301 tcatcgagaa aaacatggac ccgatcacgt ccgtcgatga tccgtaattt ttcattgacc
     3361 gcatcttttt tgatcgttgt tcgatacaat aggtacccag tattctgacc caattcttcc
     3421 attgtttgag gataggtcga gtggatcggc ttgctgatgg tatccagtgt tgcgaaaaag
     3481 ctgacttttt ctttcaagtt gattcctttt ttgacgattg tttcttttat ccatggttcc
     3541 atttgctgca tttctggaaa attttctgcc atcattcgtt tcagagcaaa atatttttcc
     3601 gttggatttc cctgctcatc caatggtgca tcgtaatcat aggaagtgac ttgcggcaaa
     3661 tcaatcgcgc ctctggctga acagccattc ataaacccaa aattggttcc gccatggaac
     3721 atatagagat tgatactgcc gatctgtaat gcttctttga ctgcatccgc taattcttcc
     3781 ggatctcttt taatgatcgg ctctttccaa cgattaaacc agccatccca aaattccata
     3841 cacatcaacg gccatttttt accatgtgct tcaaaaaact gggccatatc tgcaaaattt
     3901 tcttttgctt ttgagccaaa attccctgtc gtaaaaacat catcgtcaat caaaatgcct
     3961 gctcttaatg tggcttgcca aggtccatca gaagtgaata gcggtacatc gattccacct
     4021 tcctccaagt atttttttac ttggcgcagg tatgctttct cttcaccata cgaaccgtac
     4081 tcattttcta cctgcaccat taagacgttg ccaccatgag tgactagatg aggaacgatt
     4141 ttaggtagta gcgtttggta ataccgtttg acatacttca tgaagcgagg atccgctgaa
     4201 cgaatacggc actcctttgt caatagccaa gcaggcaagc caccaaattc ccattctgca
     4261 caaatataag gggctggacg tacgattgcg tataatccaa gggattgcgc taactctaga
     4321 aaatgggaaa gatccaatat tttcgaaaaa tcataggttc cttcttcttt ttcatggaga
     4381 ttccaaggca cataggtttc cacagtatta aatccaagcg ctttcaaatt gtgcaatgac
     4441 cgctcccaat tcgtcggatg cactcggaaa taatggatgg caccagataa aattttgaaa
     4501 ggttgaccgt ctaacaaaaa ctcttctttt atttcaaatc tagtcaagca aatttcctcc
     4561 tcgtttttag aaaccgcttt ctaattttat aatcaacgaa tctttctgac gttgatttcc
     4621 cccctaaaat aatcgacttt cacaggatcg atccatcctg ttttttcttg ttgtgcattc
     4681 gccatcccac aggccatcgc aaacgcaagt gtttcttcaa tcgtatagct ctttgataga
     4741 gcatgtgcta agcctgcaat agtcgaatct cctgacccca caggattcac caccgcgatt
     4801 ttaggaatcg taacctgata gaagtgtctc cctactttag cgattgctcc ttttgcgcct
     4861 agcgaaagaa cgatccaatt gattccttca aaaagcggat gatccaataa tgattggatt
     4921 tcatctaacg aagtagccga agaaattgtt tggtggacca actctcctaa ttcttccaaa
     4981 ttaggtttga tcaaaaatgg tttttccttg ccttccaaga cttcaagcaa ggtttgacca
     5041 gaagtatcta acaatactcg tgttcctttt ttattcgtta gggcaagtaa ctctgcataa
     5101 taacttttag aaaatccttg aggcagacta cccgaaatcg taaagatatc agttgtttcc
     5161 attagtcgtg caaaatgctc ggtaaattta tgttgctctt cttccgtcac aacaggaccg
     5221 ctttccaata gttctgtttg attcactcca tgtaaaatag caatcgaatc tctcgtttcc
     5281 cctttgatag gtaaaaattg atgcgttatc cctgattgat cgagttgttc tttgatatat
     5341 gctccatgct gcccgccgac taatccagta gctaaaacat catctgctaa taaatgaagg
     5401 acacgagcaa cattcaagcc ttttcctcca gccgttttgt tgaccgtttt gacccgattg
     5461 acttggtcga tccgtaattc atccaacgtg taagcgatgt caattgaagg attcatggta
     5521 actgtcgtga tcattttgct gtcaccgaat cttcttttac tttgtcaaac caaggggtgg
     5581 cgttttcatt tatcacttta ttcaacgatt cgatattttg tcgcccttgt gttctcaacc
     5641 actcaatcgc accttctcta ccattttcaa catatgcttt gactccatct ttccaagtcg
     5701 cacgtccgca taacacaccg ttgaatgttg aaccagattc atgagcaaag atcaatgttt
     5761 gttggaacaa tgcagtcgaa acccctgcac tcaagaagat aaatggtaac ggtgttgcat
     5821 cactttgttc cttgaagaat gccgctgctt cttttttact atacgcaatt tcaccatcag
     5881 aataaccttc tacatagttc atattgactg gcacttctac tttcaataca tccactttat
     5941 atttaggatc agaaaattct ttcatcatct cgatcacttt atgcggtttg atcttcgcat
     6001 attctaatga agtgctgtca ttggttttgg catcatacga aaccaattct agataaaacg
     6061 gacgcttttc acctgcacat tcactgccta aacgttcgat aaatacatgt ttcaaatgat
     6121 tgatctctgg gtcttcatct acatcataat aaagcaaaaa cttgatcgca tcggctgttt
     6181 gttcctttaa tctaagcgta gaccaatccg ctaataaatc aggcagacgt cctggagttg
     6241 tcgcatcata acccgttttt tcataggcta aaagtagtcc tgcttcctga tgtctggctt
     6301 tagcagctgg caatccatac tctggatcta gtaaaatagc agaagcataa ggcgttaatt
     6361 ctgctgatac taattctttg aattcagtga tctgttgcgc cgttggttct tttcctaacg
     6421 ctttgatcat ctttttcaaa gcaccgcgtt gatcaattgc caatgcactg atgattcctt
     6481 cttttgttga taaactcttc atagctgcaa ttttttcttc attcatcctt cgtttcccct
     6541 ttgttcacat attcatggat aatgacacct ttgaccactc gattgactgt acctgtaggc
     6601 gatggtgtat ctggtttatt cgctactttt atcgacgtat cgagcgcaat gatttgggct
     6661 gtcatgatca taggtaaggc aagatacgca tcaggtaggc tgatcgaagc ttctaacaaa
     6721 agacttgtac ctgtgaaatc gatgtttcct ggttgggcga tcgcgatgac actcgtggta
     6781 atttggtcat cttttatttc ttctagaata tctaagtcat aatttcttgt atacggttgg
     6841 ttattaacaa aaccaataac aagtgtttcg ctatttaaaa acgattttgg tccatggcgg
     6901 aagcccatag aagaatcaaa gatcgttgcc actttaccgg ctgtcaattc caatattttc
     6961 aattgtgctt ctctcgttgc accagccaaa cttcctgaac caagataggc gatacgttca
     7021 aatgacttag gcaataattt ttggatttct tgatctcgtg aaattagatc ttctccagtt
     7081 ctgatcaatt gttgaagata actttctttt ttctcaacgg cagtttggtc gaatacccat
     7141 aacgcactca acaacatgca cgtaaaactt cctgtcatgg caaatcctgc atcatttgat
     7201 ttttctggca tcagtaaaag ataatttcgt tcatctgtcg ctgcattctt tgctaactga
     7261 ccttctttag cacaagtaat cgtcaaatga aacaatgtct tgatttgttc attggcaatc
     7321 ttgactgttg ccacactttc tggactattt ccactacgtg caaatgacac cagtaatgtc
     7381 ggttcatccg gaaatagaaa ttcttttggt gaagacacga tatctgtcgt accaaagcta
     7441 tgaaaaataa agtgatcgtt atcaccgtat tcatttaaat aaggtactgc tgtatccccg
     7501 acatattgtg atgtgcctgc accagtaaaa atcactcgaa ctcttttgcc atttgctgct
     7561 ttttttatct ggtcaaaaaa caatgctaat ttttcttgat tctgtgctaa tatctcagct
     7621 gtttctttcc ataattgcgg ttgctgtttg atttctcgcg tagttatttc cgcacccaac
     7681 tcttttaatt tatccttcga tagttcaaac atgttgtttt ccctctcaat cattttcgga
     7741 cgtggcggat cttataatga aactggtctg ctctcgctac actatccgta tattcaataa
     7801 tttcattttt cacattatag gtcgttcggc ttagatataa taccggggca ccatcagcga
     7861 tacgaagcgg atcagcatct ttcttttgaa cgatacttgc ataaaattct tcatctgcta
     7921 attggacttg ctgttcataa tcctgagaaa acacatcata caatggctta ctttcaagta
     7981 atggcagatc aagaccaata aatagttttg caggtaaata agaacgttcc accatcaatg
     8041 gttcgtcatc cgctaaacga agtcttttca atttgaaaac tgtttcgcct aaattgatgt
     8101 ttagattctt ggcaaccttt ttgtttgctt ccatttgctt gaattccaag atgactgtat
     8161 taggcacccg tcccaattcc ctcatctctt ctgtaaaact atacgctccc gccagatcag
     8221 acgacttatc tgatagatca gacacatatg ttccttttcc gtgtcggcga taaatatacc
     8281 cttgcgtctc taattcttgc aaagcaaggc gaaccgttgt ccgactcact ccataatgct
     8341 gacaaagttc tctttcagat aacaatttgt catgaggtgt catctgtgtt tcgatacgtt
     8401 ctttcaatac gtcaactagt tgataatata atgattttcc tttacttgag ctctccataa
     8461 aaatacctct tctttactgg ttataaccac aacacaagaa tacccacata ttcctcattt
     8521 gtcaaagggt ttttggcgta aaaaagctat tataacaagg tttcaaggta atttagaact
     8581 ggtatcaaaa gatacctcaa aaataccagt tgacaaataa aaaacaaaaa aaagctgaat
     8641 cttggcaaag attcagctaa atggtctaga gaagtaaaga aaaaatattc tttatacatc
     8701 tgtggctatt tctactatcg acaagcaaat gggcctaata gactactatg taaataaaaa
     8761 tggctttctc taaataaagt aggatttttt attttttaga taacttttct ctcatgccgg
     8821 tctgatagtc gaaattttgt tgtacatttt taaaaataac aaaaattttt tatgataatt
     8881 ctgtcttttt ctagtttcct tatggcgtaa gtttaacgaa taagaattta gtatctatac
     8941 ttttatatta caaaaaatat tcgtaaaatt cgggctctat acttttcgat gtttgtgaac
     9001 tttatcaaca tcttttttgt ataaaaaaat atagaaaaga caccctgaaa tcctttagaa
     9061 ttaatttgcc caacaaattc ataggaggat tcaagatgtc tcatactctg cttatcaaag
     9121 ataccctaaa tattctagac ctaaatatca atatccattt cgaggaaaat tgtttaacta
     9181 aagaaaaata caaaggacaa atttgcttga tttacaaagg gactcttcag tacacaccag
     9241 aagaatatcc acatcttcca atatattaaa agaaccttct tgaatcattg agtgaaagaa
     9301 aagagattcg tcactatttg aggactgttt aactagagac attagcgatc tgcctgaaac
     9361 ctatacaacc actttacgaa cgtttaaaaa ttttctgcca cagattcaaa atgcgcttaa
     9421 ctgcagctat tcaaacagac cattggaatg tttaaacaac cacatcaaag tattaaaacg
     9481 caatacgtat ggctttcgca gcttttacaa tttcaaacta cggatcatga ttcgtcatgg
     9541 caaaacattt ttaaccaaat aaacagaaga atgtgggata aatctaaaaa tcagttttgc
     9601 tacagactct cgagtaaacg gcgggagcag aagcaactcc ttcggaaata agccgaaatt
     9661 cacaaaaatt tgaaaagcaa ttttcgtgaa tttcttctta tttctcggag ttaaacactt
     9721 ctgtcccagc ctcttctgtc caaattattc taagatttct ctttaccaac atcatttgac
     9781 aaagagcttc ttttttgaat actatattcg ttctgttttt catcttcaaa tacgaactca
     9841 tccgcagaaa tatttgtcac aactccatga atcttctttt cattaccacc tatataccac
     9901 aggattccta cacagaaaca acaaaaaaat agcataaaat aggttttctt tattttatat
     9961 ccctcctttt agattaaaag ctcacagaaa acgctttcta aaaagacaat agaataatca
    10021 taatttttca ttttgtatta tttatacaaa taatacgcat gttactgaaa aatgatatgg
    10081 ttccctactt tttgagataa gttaaataaa atctgtcatc gataaaacag ctagtacagt
    10141 aatgataaat agtaagaact taaaatattt tggattttta tttttgaaat aatcgaagaa
    10201 aagtaaaagt gataacgaaa tagcaaacaa gattatatct ataagattat tcattgagaa
    10261 atcgccccat atggaactct attttgacct gacacaccga gacataaagc aatcatatcc
    10321 tctgcattgt tttatactat tagaactata gctacaccta ttggatgcta ctggctctaa
    10381 gattaatgct aatacagtaa catcaatacc taaactagca gaaactctat ttgcatcttc
    10441 aatttcagat gcctggactg tcgtgactag cgccgtagta gaaaaattta ctggtactaa
    10501 caaagatgca gacacgactt ttatttcact tatcctttat cccataacct aaacttcaat
    10561 cattacttgt gagctgatca atgttcttcc aagtctgaaa gaacattgat cagcttggca
    10621 aacaaataat gttttcaaat acttgatcga tgaaaaaaag ctattggtaa taacagtaat
    10681 tgcattttcc attttcgtgt cagatacttc gcttacagct ggtaaacgat caatcccatt
    10741 gtcaaatttt ggattttttt ctgatgatgt cttgctttag ttcataaaat aatccagcaa
    10801 taaattcctc gcaaggatag ccaacttcat tttcctaatc ggaattttta aacttatcgg
    10861 tatagataca gatgcaatga gaacaaacat ttatttcgag tcaccatcta aaatattttc
    10921 ctccatgtac ccgttcatta ttatttagtt atcaccaaag atatctctgg tataaacttt
    10981 ttcttcaaca tcctttaaaa tatcttcaaa ccgattagat acgatcacat cagaaatatt
    11041 tttaaattca ttaatatctt tcaatacttg tgaatgataa aattcatctt catccaatgt
    11101 aggctcgtaa acaaccactt caattccttt ggctttaatc cgtttcataa ttccttggat
    11161 cgacgaatat cgaaaattat ctgaaccggc cttcatcgtt aaacgataga ttccaacaac
    11221 atttggtttt ttcgccaaaa tctgtccagc aataaaatct ttccttgttg tatttgcatc
    11281 aacaattgca ctgatgatat tgcttggtac tttttcatag ttggctctta attgttttgt
    11341 gtctttgggt aaacagtatc caccatagcc aaaagaagga ttattataat gcgaaccgat
    11401 ccgtggatcc aaaccgacac cttcaataat ttgcttacta tcaagcccac gaaattctgc
    11461 atacgtatct aattcattga aatacgccac tcgcaatgcc aaatatgtat tcgagaataa
    11521 tttaatagct tctgcttcag ttgagtgagt caaaagaact gatgcatctt tgttaaatgc
    11581 gtttctttga aacatagttg caatctcgcg accacgagca gaacattctc caactataat
    11641 tcttgatgga tataagttgt cgtacaaagc ttttccttca cgcaaaaatt caggtgaaaa
    11701 aatgatgttt tctgtaccaa atttcgcttt aatttcattt gcatagccaa ctggaactgt
    11761 cgacttaata atgaatgttg aatctggacg aattgctaaa gccttctcaa ttacatcttc
    11821 tactgttgat gtattaaaat agtttttctt ttcgtcataa tctgttggag ttgcaataat
    11881 caagtaatca ccgaagttta ctgcatcagt aaaatttgac gtaaattcga catttaagtc
    11941 atcccgtttt aaaaattcat gaacttcttt atcttctatt ggtgagatgc cattttgtaa
    12001 catcgtgatt ttttcttcca cgatatcata agctttgacc tgctcttttt gtgctaataa
    12061 tagtgaattt gctagaccaa catagcctaa tccgaaaact gaaattttca tattcttcca
    12121 tacgctccaa tcaaatttca ttttatagta ttttagctgt tatccttttg aacatattcc
    12181 ttattcaatc aatattattt aatagaaaaa atttttttgc ttcaaaatca tcgaggttcg
    12241 atatttaata aattcatttt tatttttctc ataatgctcc tctatagttg aaatcacttt
    12301 acatgaacta cccgctacaa cactattatt tgggatatct ttatttacta aagtgttcgc
    12361 tctaataatt acattatcgc caattgaaac tcctgggaaa acaatagagt aaataccaat
    12421 aaaaatatta tttcccaatt tgatcctacc tatttttgaa gttgactcgc tcacagaact
    12481 catcttcctt aagacccaga ctccaccatc gtgtgttata aatttaacac caaatgaaca
    12541 tctgaaatta tcccctattt caattaaata tggctcgctc ccaaattcag gaacctctac
    12601 taaactatgt ttttttccga atatcaaacc ttcattaata cattctcgca gattttttcc
    12661 aaatagtttt ctctttattc ttcgaaagat tctattctta cttcgtatac cctcaccttt
    12721 tagccatttt tattctgaaa aattttttta gatacgttat aattaattgt ttatacgtaa
    12781 aaacgaaaat agcactaaaa ataatcgtta agaaaagatt aaaatagaag cctctatgaa
    12841 tgcatacaaa agcgattgcg gaatagagaa ctaaaagtag cgatattcgc ttccaatcaa
    12901 atgcataata agcaattttc cttccaaaat aatatctaag tccaaataat actaaagtac
    12961 cgagcaaagt agcaaatgag acaccaatta ctccaaaaga atagcctaat aaataggtgc
    13021 caacaacact caatagacct gacactactg aaatcattaa taactgattt gttttattgt
    13081 atactgcaaa tatatttccg atatttgttg tcatcccact gaaacatgcc ataataacta
    13141 atattggaac tagaactaat gattttttat aatcagggtt ggttataaaa gagtatgcac
    13201 agcaaatgat aggaatagaa agagtcgcta acctaatgta cattttaaaa atataggtat
    13261 ttttctcaac gaatctttcg atgaaatcat cattctcaga cgtgata
//
LOCUS       DAFKHN010000067        13299 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFKHN010000067 DAFKHN010000000
VERSION     DAFKHN010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.067"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            21..623
                     /locus_tag="LY912_002091"
     CDS             21..623
                     /locus_tag="LY912_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955749.1"
                     /translation="MNIDRLKTMYDGYDGDRVIEIRFIDPRRFTVQQRNFIYALIGDI
                     FIDTGMPTDFWKEFFYFRFEGVTGREISLKDESNTTVSDANILANIILDFIFEHHIPF
                     KEGYEILPANQEYYFYKCITKRVCCICGKTGADIDHFDKALGRRKRKEVDHSEYTFAA
                     LCRIHHTEKHKIGVTNFKNKYQIKGIKLNQETIKKLRIGG"
     gene            626..853
                     /locus_tag="LY912_002092"
     CDS             626..853
                     /locus_tag="LY912_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955750.1"
                     /translation="MINLNAVAFEQTWRTKYKKMSPRDKLFLEIMTFAFIGTQAEQSD
                     ISVEKIKTNRLVNGITETCYQYTIIVVDEEE"
     gene            856..1683
                     /locus_tag="LY912_002093"
     CDS             856..1683
                     /locus_tag="LY912_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HBM6955751.1"
                     /translation="MAERRMFAKTIIDSDAFLDMPLSTQALYFHLSMRADDDGFINNP
                     KKIQRMVGCGDDDLKLLMAKRFILVFESGVIVIKHWKIHNYIRNDRYKPTLYQDEKAL
                     LADKDNKAYTFAEELSKHDEKLGIPDDNQAVYQMDTQVRLGKDRLGKDSKEIKDLTPS
                     KKSKAKPIRHKYGEYKNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESSGKTYKNYL
                     ATIRSWARKEKSESKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            1695..1964
                     /locus_tag="LY912_002094"
     CDS             1695..1964
                     /locus_tag="LY912_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955752.1"
                     /translation="MKIDYLELINEIANYKTGEEIDILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDATQLRNLAYTKLLFVDCIKGLQKHLSELEQV"
     gene            2126..2428
                     /locus_tag="LY912_002095"
     CDS             2126..2428
                     /locus_tag="LY912_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955753.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVTEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK"
     gene            2425..2736
                     /locus_tag="LY912_002096"
     CDS             2425..2736
                     /locus_tag="LY912_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBM6955754.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            2733..2951
                     /locus_tag="LY912_002097"
     CDS             2733..2951
                     /locus_tag="LY912_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HBM6955755.1"
                     /translation="MIGLTIFWCAIGGLLAFLGYYLICESRKGRKYTVTGIVLLIIGI
                     LVAVGAELNLYVNGTQEDLVRFMFWMKN"
     gene            2962..3777
                     /locus_tag="LY912_002098"
     CDS             2962..3777
                     /locus_tag="LY912_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBM6955756.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            3916..4272
                     /locus_tag="LY912_002099"
     CDS             3916..4272
                     /locus_tag="LY912_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBM6955757.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGVGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKAHSIQHGFI"
     gene            4259..4477
                     /locus_tag="LY912_002100"
     CDS             4259..4477
                     /locus_tag="LY912_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955758.1"
                     /translation="MDLYDIESGATVSVESDHLIISFADERQIIIWVVDDMLYPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSK"
     gene            4474..4872
                     /locus_tag="LY912_002101"
     CDS             4474..4872
                     /locus_tag="LY912_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBM6955759.1"
                     /translation="MIPKFRAWDKRENTMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVEIFEGDVVITSKGAIGYVAYLQQEAGFVVVLKKSDYRLG
                     HRNTGESYDVATAHEVIGNIYENSELLEVE"
     gene            4869..5207
                     /locus_tag="LY912_002102"
     CDS             4869..5207
                     /locus_tag="LY912_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955760.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            5204..5434
                     /locus_tag="LY912_002103"
     CDS             5204..5434
                     /locus_tag="LY912_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955761.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            5441..5644
                     /locus_tag="LY912_002104"
     CDS             5441..5644
                     /locus_tag="LY912_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBM6955762.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASETIRKFGISILNDDRKWEAER"
     gene            5641..5934
                     /locus_tag="LY912_002105"
     CDS             5641..5934
                     /locus_tag="LY912_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955763.1"
                     /translation="MKLKDGFYTDAYGIGGLMMDLPTKNPIKQEESEIKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVVRLVDMEVIKS"
     gene            5964..6404
                     /locus_tag="LY912_002106"
     CDS             5964..6404
                     /locus_tag="LY912_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBM6955764.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            6479..6946
                     /locus_tag="LY912_002107"
     CDS             6479..6946
                     /locus_tag="LY912_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBM6955765.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            7223..7459
                     /locus_tag="LY912_002108"
     CDS             7223..7459
                     /locus_tag="LY912_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955766.1"
                     /translation="MYWRVYKMNNASEKIDQLTILVNQRIEDIIKEFEGEKIKSIKLT
                     LMDHKFELNSTKRKIVELIEKEIAVQINEQQLTN"
     gene            7483..7695
                     /locus_tag="LY912_002109"
     CDS             7483..7695
                     /locus_tag="LY912_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955767.1"
                     /translation="MDKESARELYLSKFKRNNKPEEVFGSNVKEVGEKLTQLLKEEDL
                     TYDEAYASLQYCYNLLKYESNFLKLQ"
     gene            complement(7673..8146)
                     /locus_tag="LY912_002110"
     CDS             complement(7673..8146)
                     /locus_tag="LY912_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955768.1"
                     /translation="MNLSEVQAAYFILNCLDPDNYTVKLYVKNGCKIFSADFLKLSET
                     GWSVIQESLDEDFDFSNPKISIASGAEKGFLWAKAAKTWNDSFSYPRQSVKLLDHPQL
                     LLEKIKAFIGNLQIEDYREFSTLAYNTEYIDGKKFNFCLLPESNYELFTIEVSEN"
     gene            8279..8494
                     /locus_tag="LY912_002111"
     CDS             8279..8494
                     /locus_tag="LY912_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955769.1"
                     /translation="MKTRETRAKRNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYG
                     NVVSVLSVHHQASVTVAEVEDAAVNGE"
     gene            8686..8898
                     /locus_tag="LY912_002112"
     CDS             8686..8898
                     /locus_tag="LY912_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955770.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQSKYFYDQL
                     ILQGFNEGQAMEFMMRTFSASNQQKE"
     gene            8905..9132
                     /locus_tag="LY912_002113"
     CDS             8905..9132
                     /locus_tag="LY912_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955771.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIIEMTREAT
                     PNEIDKYNLRYCGHGYWKDEYIQQNIERYIK"
     gene            9129..9413
                     /locus_tag="LY912_002114"
     CDS             9129..9413
                     /locus_tag="LY912_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955772.1"
                     /translation="MNDNYDYIKLIEKIRAEKDMDELANLFMNIISLVGLKMDEVAAL
                     NYFIAEQTIRAEHNAKFLKDRLDLDVKGLGVEGIFKVQEALVNVYVEKMQ"
     gene            9454..10026
                     /locus_tag="LY912_002115"
     CDS             9454..10026
                     /locus_tag="LY912_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955773.1"
                     /translation="MKLKDYIREGYNIVTTPNLAYKIQEDYPNVLVFTDRALDAIPIG
                     KLLVDRYYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWHTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            10027..10338
                     /locus_tag="LY912_002116"
     CDS             10027..10338
                     /locus_tag="LY912_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBM6955774.1"
                     /translation="MIDVSTKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            10329..10589
                     /locus_tag="LY912_002117"
     CDS             10329..10589
                     /locus_tag="LY912_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955775.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEETTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            10757..11311
                     /locus_tag="LY912_002118"
     CDS             10757..11311
                     /locus_tag="LY912_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955776.1"
                     /translation="MIGLNSKLVGTRMKQKRIEKGLTQADVATKSGISSRYYGSIENG
                     KNSPSIETLNSISIVIGCSLHFLLNDRMDDMEKRVELEKKRLQKIFDKIPHDKLNLVE
                     GLIIQAARLRVLLDDNWKDIIENGEYEKFKQSENQIAYDRKRPIVENYDNRDKTYQAI
                     VKQLTDLLPQGTRADKKSKLLGRK"
     gene            11314..13005
                     /locus_tag="LY912_002119"
     CDS             11314..13005
                     /locus_tag="LY912_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBM6955777.1"
                     /translation="MLFNQHVDQYIRKWKSGELILNEKRIQLLKLIEKEILPRDDIYY
                     FDEEQINNYIEFSQAWYFELDEWEKFISAFIFLFYKEDDEVVFDEFVINMGRGGGKNG
                     FISTLANYFVSSLHGIDYYDVSIVANSEKQAKRSFQECYRVINKKGNEDLKEEFEAYK
                     SSLTGLETQSVFEYKTSNASSQDGGREGAVIYDEYHEMENTDIVDVFSGGLGKVDHGR
                     QFFIGTKGFVREGYFDIKYRECEDILNGLSEFKGVFPYICELDAIEEMDDPKNWPKAN
                     PALQPPLNKRGKRLFNEVMKKYKKLAKEPSGRSAFVTKRMNFLEDNMENSVASREEIM
                     ATNRPFFELDTVPIGSLDFGSVRDFATCGLLFKNRKKSEYAFKSFTFAMKNFCDVHYG
                     YSLKEQLVGSEKRAPIKTWEKMGLMKVIDEPSLNPKYIVDWFIQAREEYGVRVIVVDN
                     YKADILGPMLEKEGFEVVRLKRPSSLHPLLAPRIEDGFANHKFIFGDNPLMRWFTNNV
                     YVKETQAGKQFLKKEEVKRKTDGFQAFVHALYKATELDEQIDYDDAFDMLDEIEF"
     gene            13037..>13299
                     /locus_tag="LY912_002120"
     CDS             13037..>13299
                     /locus_tag="LY912_002120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955778.1"
                     /translation="MRIKGKNISWVFYMLGILAFTFVAIKLSEIIIPNDSVVSKNLVL
                     ERAKLIISILGPALTLIVFVRTIQTQLESSKNLIKDNVSKDFY"
BASE COUNT         4846 a         2006 c         2834 g         3613 t
ORIGIN      
        1 gtgcaaccat caatgaggaa gtgaacattg atcgactaaa gacgatgtat gacggctacg
       61 atggtgatcg agttattgaa attcgtttta ttgatcctag acgtttcaca gtacagcaac
      121 gaaacttcat ctatgcactc ataggcgata ttttcatcga tacaggcatg ccaacggact
      181 tctggaagga attcttttac ttccgtttcg aaggtgtcac agggcgcgaa ataagcctca
      241 aagatgaatc gaatacgact gtgagtgatg ccaatatctt agcaaatatc atcttagatt
      301 ttatctttga acatcatatt cctttcaaag aaggctatga gattttacca gcgaatcaag
      361 aatattactt ctacaaatgc atcacaaaaa gagtctgctg tatctgtggc aaaacaggag
      421 ctgatatcga tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa gttgatcatt
      481 cagagtacac atttgcagca ctctgtagaa ttcatcacac ggagaaacac aaaataggtg
      541 tgaccaattt caaaaataag tatcaaatca aagggattaa gttaaaccag gagacaatca
      601 agaaattaag aatcgggggc taatgatgat taatttaaac gcagtagcgt ttgaacaaac
      661 atggcgcact aagtataaaa aaatgagtcc aagagacaaa ttgttcttag aaatcatgac
      721 atttgctttc attggtacac aagctgaaca aagcgatatt agtgttgaaa aaattaagac
      781 gaatagatta gttaatggaa ttacagagac ttgttaccag tacacgatta tcgtcgtgga
      841 tgaggaggaa taattttggc agaaagaaga atgttcgcaa agacaattat tgattctgat
      901 gcattcctag atatgccttt atcgacacag gcattatatt tccatctatc aatgcgcgca
      961 gatgatgatg gatttattaa taatcccaaa aaaatacaac gtatggttgg ttgtggtgat
     1021 gatgatttaa aactgcttat ggcaaaaaga ttcatcttag ttttcgagag cggtgtgatc
     1081 gtcattaagc attggaaaat acacaactat attcgtaatg atcgttacaa acccacgtta
     1141 tatcaggatg aaaaagcttt actagcagac aaagataaca aagcttatac atttgcagaa
     1201 gagctttcta aacatgatga aaaacttggt ataccagatg acaaccaagc ggtataccaa
     1261 atggatacac aggttaggtt aggtaaggat aggttaggta aggatagtaa agagataaaa
     1321 gatttaacgc cttcgaaaaa atcgaaggct aagcccatcc gtcataaata cggagagtat
     1381 aaaaatgttc ttttgtcaga tgagcagatg gagaaactca aaacagaatt ccctaatgat
     1441 taccaagagc gaatagaacg gctatctgag tattgtgaat catctggtaa gacttataaa
     1501 aactatttgg caactattcg aagctgggca agaaaagaaa aaagtgaatc taagaacgca
     1561 agcagtggat acaagcgcac aggaagacga gagaagcttc ctgaatgggc aatcgaccaa
     1621 gaagcctatc ttaagaaaaa agcgctagaa cgagctaata gacaatcaaa agcaccattt
     1681 taagaggtgg aaaattgaaa atcgattatc tagaactaat taatgaaata gcgaattata
     1741 aaactggcga ggaaatagac atcctgagag acgtatatga tcaactcgaa gaagctggaa
     1801 tcgaaggaat taataatgat cgttcgagtt ggagtaaact cagatactat ttcgcacttt
     1861 atatcgatgc aacacaatta agaaatttag cttatacaaa attactattt gttgattgca
     1921 ttaaaggatt gcaaaaacat cttagtgaac ttgagcaggt gtaatcagat ggatctaaaa
     1981 acatttacag cacagatcga actaatgcat caagaagctt taagacaaag cgcctcgtac
     2041 gaagacaagt ggctcaacac gttccatggt ggacgtgaga gcgcacttga tcaagtactc
     2101 aaattattga aaggggaacg tcgggatgga taagaaagcg gcaatgaaac gaatcatcga
     2161 actgacacat tctgagaatt ggcaagaaga caaagaaata gttacagaag tccaaaagct
     2221 cggtaaatca atgtggactg aaaagcccaa acggagaacg ccgagaaaga ttgcaatttg
     2281 gcatggtgat cgaattctag taacaggtac tgctgaacag ttatctgaaa ttactggtct
     2341 gagcaaaaac atcatctggg atagagcaag gagcttatgg attgattcaa aaggacgaca
     2401 atttaggtat gtggaggaga aaaaatgaac gaactaatca caaaagtaga gcagtgggct
     2461 aaagacaagg gactggatca agcagatcca aaagcacagt ttttgaaagt agctgaggaa
     2521 ttcggggaaa tcgcttcagc aatggcaaga agtaatgatg agctatttaa agatagcgta
     2581 ggagacgtaa tcgtcacgtt gattatcctt tccatgcaaa aagggacaaa cgtacaagag
     2641 tgtttagaaa tggcatacaa cgaaatcaaa gggcgcacag gaaaaatggt agatggtgta
     2701 ttcgtgaagt cgagtgattt ggaggacagc aaatgatagg tttaacaata ttttggtgtg
     2761 cgattggtgg tttactagca tttctaggat actacctcat ctgtgaaagt agaaaaggaa
     2821 gaaaatatac agtgacaggt attgtcctgt taattatcgg aattctagtt gcagttggag
     2881 cagaactgaa tctttatgta aatggtacac aagaagattt ggtgcgattt atgttttgga
     2941 tgaagaatta ggaggaaaaa aatgaacgaa aacaaattaa tcaaattagg tgtagcagga
     3001 gcagtaatcg taggtattgg agttatcgga ggatttaagt tcttcgaaaa aatcgataat
     3061 ggatatgtgg gtgtgcgcta ttcaatgaac ggcggtatca aagatgaagc actgacgcaa
     3121 ggtgtgaaat ttgtagggat tgacaaagtg atccaatatc caattcgctt gcaaactatc
     3181 caatcaaaaa atatttcagt atctacaagc gacggcaaaa agacaacgat tgatatcaaa
     3241 tatgactaca aagttgattc aactaaagca gcaaaaatgt acaaggaatt tgggaatatc
     3301 acttcggaag atatcgaaag tggatggtta aaatctaagc ttcaaaaggt cgctcgtgaa
     3361 gtttatgcga aatatagtct gcttgatgtc ctttcaggag attcctctaa agttgaagct
     3421 gaggtattaa cgaactttgc taaatcagtt gaatctaaag ggtttgaagt cgaagacgta
     3481 acacttggtg ttccagatgt cgataaagaa acacaaaaat caatcgatgc gatcattcga
     3541 gctggtcaag aaaatgaaaa agcgaagcta gatgcagaaa ctgcaaaaac tcaagctgat
     3601 agtgaagctt acaagaaaac aaaagctgca gaagcagagg cagaatctaa tcgcaaagtc
     3661 gccgaatcag taacagacaa tttgattcgt tatgaagaag ctcaagctcg caaaaagcat
     3721 ggatgggtaa cagtaaatgg agcagatact gtagttacgg atgaagcagg caaataatat
     3781 gggattcttt atggctaaaa ttctcttgtt cttaggttta gtaggagcag catatctcgt
     3841 gtatgcgctc ctttcccaaa ctgatgacaa agaagatgac aacaacgatg aaatgaaatt
     3901 ttaggaggag aaataatgga tctcattaca caatacagtg atatcatcct caagaaaatc
     3961 atggcaaaga ttcagaaaga taaaaaagca aaagaacgag cggaattagt taagttggaa
     4021 atggctgaaa caggagtagg agtgcgaagt agcaggcatt ggaaagcagc agcaaacatt
     4081 gaattttatt acaacgaaat tcaaaaaggg ttcgatcaga tgcgtgagct ggatcggcaa
     4141 acaaattgga gcaagaaact tcatcaagat cgtttcaaat ttgtagagaa gtataaagaa
     4201 atattagaag agtatttgag gaggacagcg aatgataaaa aagctcattc aattcagcat
     4261 ggatttatat gatatcgaat caggagcaac agtatctgtg gagtctgatc atttaatcat
     4321 aagttttgct gacgaacgtc aaattatcat atgggtagtt gacgatatgc tatatccaga
     4381 aattgtacat gattttgaag aatcaaaagc ggttgagttt gaaatagtga aaaaagtaat
     4441 ggaattgatt gaaaaatacg aggaggacag caaatgatac cgaagtttag agcgtgggat
     4501 aagcgagaaa acacaatgag agatgtagct gtcttacatt ttactaaaaa cggcaaaaca
     4561 aactttattg aatattggat aaatcctacc gaattgaaat catatcacgt gcgaaacatc
     4621 gacctcatgc aatccacagg aatgaaagat aagaatggtg tggagatatt tgaaggggat
     4681 gtagtaatta catcaaaagg agcgattgga tatgttgcgt atcttcaaca agaagccggc
     4741 tttgtagttg tactaaagaa aagtgattat agattaggcc ataggaatac tggcgaaagt
     4801 tatgatgtag caactgctca tgaagtcatc ggaaatatat acgagaatag cgagttattg
     4861 gaggtagagt gattatctta gctactgact acatcgattc tttaaaagat gaaaatggga
     4921 atgtcccagc attgctaaat tgtggaatta aaagcaagaa tagaatcatt ttgttacgga
     4981 tatcggctga tttagcaaaa tatctttatc tgagcaagac agcagtatat tacactgcgg
     5041 ctacacgtta tcagtacaag ggaaaaacaa tcagtcagga ttattatgat cgtttaatca
     5101 gtcctgacat gcatggaaaa tcaaaatcag cgatcaagtt atttggcgca atagagatat
     5161 atgccgatga ttttccaaat ttatggttga aggaggaagc ggaatgaaat acgaaatacc
     5221 actaagtgaa gcgggcattc aagcaattat caatggtcgg gaggttaata aaaaacttcc
     5281 tgatggtact gaattagtca tcagacaaag ttatttgaaa gatatggcag ctccagtatt
     5341 aattgatcgt tttaacgtga ctgattctgt ggtagagaac cacttgaaag aatttcgatc
     5401 aagtataaac gacactttca gattagggag ttgattgaca atgaacacca gacaccgcag
     5461 agtagcaaaa ctaagaaaac aggaactgaa tgtactaaag acaaagtttg aaaaagaata
     5521 tggaatttca gcagaagaaa catataaagt ggcaagtcag tttgttgctg atgcgagtga
     5581 gactattcgt aagtttggga tttcgatatt aaatgatgat cgtaaatggg aggcagaaag
     5641 atgaaactaa aagacggatt ttacactgat gcttatggaa ttggtggttt gatgatggat
     5701 ctaccaacta agaatcctat aaagcaagag gaatcagaaa ttaaagtcgg tgacatggtt
     5761 cgctgcgaag cagaagggtt catctatcca tttcgtggat atgtagagca tctctataat
     5821 cactcagcga tcattcgcat tgaaaacacg atggaatgtg acaagcggtt agcgaaaagc
     5881 aaagagaatt tagcagtggt gagattggtg gatatggaag ttataaaatc ttaattttgc
     5941 ttttttacaa ctatcctaca acaatgagcg ttattccaca actggaagga gaagaggcaa
     6001 ttgtgaacat tttagagaat atagatatta agcaaacaag gaaaaatgct agacgattac
     6061 taaaaagata cagaaattta gaacgtttgg tcggaccagt gaaaatagac ttttccgtga
     6121 tgactgttac caaaaatttg aaattcacaa ttgacagtca aaacgaagaa atcattgaag
     6181 cgataagtac tcgagattcg gttatcgaag cattaacacg gctaagtaga atccatttcc
     6241 aggtacttta ttatagttat tgttttccta ataagatgtc aatgtatcaa ataggagaaa
     6301 aattaggata ttccgataga actatcgaga gaatgaaggc agtagctttg gttgaatttg
     6361 ctgaggcgta taaatcagga gaactcattt cacgtacaaa ataaaaaaag tcggattcct
     6421 ccgactatga ataatatttc cgacataagt attatatcat aattggggga atcagaggat
     6481 ggtacttttc gatgtaaaga aatatgagac accaagcgcg aaagatgttg atatggaacg
     6541 cacaaaacat aatgtcgctg tgtttctttc agcatatcta tcagctagat gtagagtagg
     6601 gcaacctcga gaaccaaaag tgacagcatc ttattccttg gttccacctt ctacagctga
     6661 tcatatattt gaagcagaaa gaatgctgat cgataaagaa gaagcacagg aagaatttga
     6721 gtatctgcat aaattgtttg ttcgaggcta ttcagcgata cagcatccgc ataagcctga
     6781 tgtgactgaa aggcgcaaga agatattcta tgatcgttat atcaatggtc tgcccattta
     6841 tgtaactgct caaaggaata atactagcga agaatcggtt aaagtagaat caaacagaat
     6901 tatcatccaa tttgcttcat cgttagaact ggttgctttc aagtagccag tttttacact
     6961 ttttataccc ttttattacc aatttggttt ccattttata ccttttttat accaatcact
     7021 tacctattca acgttgtatt atgatagtgt cgaaagatta gtgataggtc ttagacaaaa
     7081 taaaatgtaa gggaggaaat ctccctcatc gttttaaatt aagcctcgat agacagcagc
     7141 ggaaatatta agaataagga tgtgaactca actccttcta aattgttctt attatctatc
     7201 atccgttgct gtctattaat ttatgtattg gagggtatat aaaatgaata acgcttccga
     7261 aaaaattgat caactaacta ttttagtaaa ccaaagaatc gaagatatta tcaaggaatt
     7321 cgaaggtgaa aagattaaga gcataaagct tactttaatg gatcataagt tcgaactaaa
     7381 ttcgacaaaa aggaagatcg ttgagcttat agaaaaagaa attgctgtcc agatcaatga
     7441 gcaacaatta actaattaat ttatgcatcg gaggaaaaac gaatggataa agaaagtgca
     7501 cgagaacttt atttgagtaa attcaaacgt aacaacaaac cagaagaagt ttttggatca
     7561 aacgttaaag aggttggaga aaaactaact caattattaa aagaagaaga cttaacatat
     7621 gacgaagcat acgcaagtct tcagtactgt tacaatctat tgaagtatga gtctaatttt
     7681 ctgaaacttc aatagtaaat aattcgtaat tggattctgg caacaaacaa aaattgaatt
     7741 tttttccatc aatatattcc gtattgtaag ccaatgtaga aaattctcta tagtcttcta
     7801 tctgcagatt gcctataaaa gctttaattt tttctaataa tagttgggga tgatccaaaa
     7861 gttttactga ttgtctagga tatgaaaaac tatcattcca tgtcttagca gcttttgccc
     7921 aaaggaatcc tttttccgca ccacttgcta tggatatctt tgggtttgaa aagtcaaaat
     7981 cttcatccaa actttcttga atcacagacc aacctgtttc agagagtttt aaaaagtctg
     8041 cactgaaaat tttgcaacca ttcttaacat acagtttaac agtataatta tcagggtcta
     8101 aacaatttaa aataaaatac gcagcttgaa cctcgcttaa gttcatattt ttcaccacct
     8161 ataatttatt tcagcggacc actcgctgat aactaaaatt atacgcttag tatttatttt
     8221 cacaatatta atttgtcact gtggcggaaa gggtagacgc tatatctggt aggtatgctt
     8281 gaagaccaga gagacaagag ctaagcgcaa ccatgcaagg ttcgattcct tgccagcgac
     8341 attaaatgcc tatgacggtt acgactaccg aaaaaagatc gttaagaagc tatacggtgc
     8401 tacgtacggc aatgtagtaa gtgtgctatc tgtacaccac caagcttcgg tcactgtggc
     8461 ggaagtagaa gacgcagcgg taaatggcga gtagcctcgt gagagcctgg taagttctcg
     8521 tgagtggtgc aatcccactc cagcgacttt aagcaaccga ggcatcggcg gtttaaaaat
     8581 ataggggtgc gcaatttcgt acgcgttttg tgcatcgtgt aggttgctat tacatattag
     8641 atcactcatc gagtgatctt tttattttga aaggggagta aacaaatgaa cgaaaaccaa
     8701 ttaagagagt tgtttaaaac gaatgaagca aacaaaacaa tggaggcgac attctacgaa
     8761 actcaaaaaa gcttagcgtt aatcgcaaaa caatcaaagt atttctacga tcagcttatt
     8821 ctgcaaggat ttaatgaagg acaggctatg gaatttatga tgcgaacctt ttctgccagt
     8881 aaccaacaga aagagtgata cataatgaga aactactggt atatatcgct aactaatgaa
     8941 tatcctcgaa ccattgatga ttgttcagtg cgtgttgtgc gttctgtaca aatcaaaaag
     9001 aagtactcca tcattgaaat gaccagagaa gctacaccaa atgagatcga taagtacaat
     9061 cttcgttact gtggccatgg atattggaaa gacgaatata ttcaacaaaa cattgagagg
     9121 tacatcaaat gaatgataac tatgattaca tcaagttgat tgaaaagata agagcagaaa
     9181 aagatatgga cgaactagct aacttattca tgaacatcat tagtttggtg gggttaaaga
     9241 tggatgaagt agcggcacta aattatttca tcgctgagca aacaattaga gcagagcaca
     9301 atgctaagtt cttgaaagat aggttagatc tagatgtaaa aggattaggc gttgaaggga
     9361 tattcaaagt gcaagaagcc ttagtgaatg tttatgtcga aaagatgcaa tagcattaac
     9421 aagtaattat tggatgtttt caggagggaa actatgaaat taaaagatta tatcagggaa
     9481 gggtataaca ttgtaactac accaaatcta gcttacaaaa ttcaagaaga ttatcccaat
     9541 gttttagtgt ttactgatag agctttagat gccattccta tagggaagtt attagtagat
     9601 cgttattata gcaacaatcc agctgttctt agtgctaagc cacttcaaaa cgcttatgct
     9661 attgaacgct ttacttgcga gtttactgga tatgagacgg tagtaccaat gacaggcgag
     9721 acaggaagaa aagtaattca acagatcaaa aagaggattg ctgaattgac gttagatgat
     9781 ggaagtaata cgaaccttct agaaatcaaa ctaagagata ctgactcagt accagaagtt
     9841 tattataaag gtcaacgaat ggatgagatg ccgataggtc ttgtcgatat tacttatcat
     9901 tggcatacgg aagaatatga atgccaagta ccaaaaggag ctaacgacat cactattgaa
     9961 tattatgatt cacataataa caagtactta gatagaaaaa tcattgggca caagagagat
    10021 atgtaaatga ttgatgtttc aactaaacaa gcaagagcta ggttctatgg atcaactgag
    10081 tggaggaaac ttagaagtca atgcttagag cgagatcatt atgagtgcca atggtgtaaa
    10141 gcagagggta gactaacaac tcaacatgat tcaattcttg aagtggatca tataaaggag
    10201 ctggagtatc atccggattt agctctagat ataaacaacc taagaacctt atgcaaagat
    10261 tgccataaca aaaggcacaa ccgtatgaaa tatcgtggcc aacaaaagaa aagaaagtgg
    10321 gatgatgaat ggtggtaaga aaaacagcaa acagagatga tgtcaaacga gcagaagcaa
    10381 tcgctatggt tgataaggct attgataagt tggttctatt taagagtcag ctcattgaag
    10441 aaacaacaac tgtagaggat atatctatca acaatagact aataggtaac gctaatgaag
    10501 taacagggac atttaatatt aatgtagaca ttgattatac cttgagtcca tttgcacata
    10561 ttgtagaaag caacgagcaa gacggctgat aaatcagtat aaagcgaaga tatatagagt
    10621 gaaatacccc cggtcaaaag attttgagaa gaaataaaat ttttgggaac cggtggatgg
    10681 ggttaattct gcaaatgcaa cgtatttatt ttacccctcc cccctccgcc gcccctttag
    10741 taaatataga aggaaggtga ttggtttgaa ttctaagttg gttggcacga gaatgaaaca
    10801 aaaaagaatt gaaaaaggat tgacacaggc tgatgtagca acgaaaagtg gtatttctag
    10861 taggtattat ggaagtattg aaaatgggaa aaattcccct agtatcgaaa cgttaaactc
    10921 aatttccatc gtcattggat gcagtttaca tttcttactc aatgatcgca tggacgacat
    10981 ggaaaaacgc gtagagctag aaaagaaacg tctgcagaag atattcgata aaattcctca
    11041 tgacaaactt aatttagttg aagggctgat cattcaggca gcaaggttac gtgtcttgtt
    11101 ggatgataac tggaaggaca tcattgaaaa cggggagtac gagaaattta aacaaagcga
    11161 gaaccaaatt gcttatgata gaaagcgtcc tatagttgaa aattatgata atcgagataa
    11221 aacttatcaa gccatcgtca aacaactcac cgatttatta ccgcaaggca caagagcgga
    11281 caagaaaagt aagttactcg gtaggaaata aaaatgcttt ttaaccagca cgttgatcaa
    11341 tatattcgta aatggaaatc tggtgagtta atccttaacg aaaaaaggat acaactttta
    11401 aaactaatag aaaaagaaat attacctcgc gacgacattt attacttcga cgaggagcaa
    11461 ataaataatt atatcgagtt tagtcaagca tggtattttg agttagatga atgggagaaa
    11521 tttatttctg cattcatttt tttgttttat aaagaagatg acgaagttgt ttttgatgaa
    11581 tttgttatta atatggggcg tggcgggggt aaaaatggct ttatttcaac attggcaaat
    11641 tattttgtca gttcgcttca cgggattgat tactatgatg tttcaattgt agctaatagt
    11701 gagaaacaag caaaaagaag ttttcaagaa tgctatcgag taatcaataa aaaaggaaat
    11761 gaagatttaa aagaagagtt tgaagcgtat aaaagcagtc taaccggttt agagacacag
    11821 tctgtttttg agtacaaaac tagtaatgca agctctcaag atggcggtcg agaaggtgca
    11881 gtaatatacg acgaatacca cgaaatggaa aacacagata ttgtagatgt gttttctggt
    11941 ggactgggga aagttgatca cggacggcaa tttttcattg gtactaaggg gtttgttcgt
    12001 gaaggttact ttgatattaa atatagagag tgtgaagata ttttaaatgg tttgtcagag
    12061 ttcaagggtg tatttccgta catatgcgaa ctggatgcca ttgaagaaat ggatgacccc
    12121 aaaaattggc cgaaagcaaa cccggcactg caaccaccgt tgaataaacg tgggaaacgt
    12181 ctgtttaacg aagtcatgaa aaagtacaaa aagttagcta aagaaccttc tggacgctcg
    12241 gcatttgtta ctaaacgaat gaattttctt gaagacaata tggaaaactc tgttgcttca
    12301 agagaagaaa taatggcaac aaatcgtcca ttttttgaac tagatacggt accgattgga
    12361 tctctcgatt tcggtagtgt tcgagatttt gctacttgcg gtttgctatt taaaaatcga
    12421 aagaaatcgg aatacgcgtt taaatcattt acgtttgcaa tgaaaaattt ttgcgacgtt
    12481 cattatggat actcgttgaa agagcaattg gttggcagtg aaaaacgggc accaataaaa
    12541 acttgggaaa aaatggggct gatgaaagtt attgacgagc catctttaaa tcctaagtat
    12601 attgttgatt ggtttattca agctagagaa gaatatggag tgagagtaat tgtcgtggat
    12661 aactataagg cagatatttt agggcctatg cttgaaaaag aaggatttga agtagttcga
    12721 ctaaaaagac catctagttt acatccatta ttagctcctc gtatagaaga tggatttgca
    12781 aatcacaaat ttatttttgg agataatccg ttaatgcgtt ggtttactaa taatgtgtac
    12841 gtaaaggaaa cgcaagcagg caaacaattc ttaaaaaaag aggaagtcaa gcgtaaaact
    12901 gatgggttcc aagcatttgt acacgcattg tacaaagcta cagaattaga tgaacagatt
    12961 gattacgatg atgcttttga tatgttggat gagattgaat tttaaggtat acttttcttt
    13021 acaaaggggt gctttcatga ggataaaagg aaaaaacata tcttgggtat tttacatgtt
    13081 ggggatttta gcttttacat ttgtggcaat aaaactatca gaaattatta ttccaaatga
    13141 cagtgtagtt tcaaagaatt tggttttaga aagagctaaa ctaattattt caattttagg
    13201 accagcatta acactaattg tttttgttcg aacaattcaa actcaattag aatcttcaaa
    13261 aaacttaatt aaagataacg tcagtaaaga tttttataa
//
LOCUS       DAFKHN010000068        13208 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFKHN010000068 DAFKHN010000000
VERSION     DAFKHN010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.068"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            144..1013
                     /locus_tag="LY912_002121"
     CDS             144..1013
                     /locus_tag="LY912_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBM6955779.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1222..2247
                     /locus_tag="LY912_002122"
     CDS             1222..2247
                     /locus_tag="LY912_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBM6955780.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKTVLPK"
     gene            2286..3236
                     /gene="manA"
                     /locus_tag="LY912_002123"
     CDS             2286..3236
                     /gene="manA"
                     /locus_tag="LY912_002123"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBM6955781.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            3330..5033
                     /locus_tag="LY912_002124"
     CDS             3330..5033
                     /locus_tag="LY912_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBM6955782.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5035..7068
                     /locus_tag="LY912_002125"
     CDS             5035..7068
                     /locus_tag="LY912_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBM6955783.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7079..7519
                     /locus_tag="LY912_002126"
     CDS             7079..7519
                     /locus_tag="LY912_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6955784.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(7719..8846)
                     /locus_tag="LY912_002127"
     CDS             complement(7719..8846)
                     /locus_tag="LY912_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955785.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8849..9526)
                     /locus_tag="LY912_002128"
     CDS             complement(8849..9526)
                     /locus_tag="LY912_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955786.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9790..11556
                     /locus_tag="LY912_002129"
     CDS             9790..11556
                     /locus_tag="LY912_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBM6955787.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNIFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11571..12008
                     /locus_tag="LY912_002130"
     CDS             11571..12008
                     /locus_tag="LY912_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6955788.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12021..13172
                     /locus_tag="LY912_002131"
     CDS             12021..13172
                     /locus_tag="LY912_002131"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBM6955789.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
BASE COUNT         4488 a         2293 c         2730 g         3697 t
ORIGIN      
        1 ataagagttt ttactcatta atttacaaaa aacaagcaaa atgcgaattt tctcacattt
       61 tttttaacaa aatcaaagtt attgcttgaa agaagaagaa tccatcgtta aaataaagct
      121 tgacgtagag gggagcaaga aatatgaaag attttcaatt gggggctgcc acctatttaa
      181 aaagtgtagc cattcgggtg aaagaccgag ataaaatgat tgatttttac aagaacgttg
      241 ttggctttga tttgaaaaga gaagaaaacg aattagccat tttaggaaca gaagaagctg
      301 gaagtgaaat gttgctgctg gaagaaagtc ctagagcgaa tgatcacatg ggggtgatca
      361 aaaagctgaa ccgtttttca ttgattatcc ctagcacaga agaaatggca gatatccttt
      421 gtcgtatccg taaaatgaat tatccaatca aagaagcttt agaagatcat ggacgtatgg
      481 ggattttgct cgtagaccca gaagagaatg aattggaaat ttaccatgaa gagaataaga
      541 acgaccaaag agaaattcca gaaacaatgg atcaagaagc attattaaga aaatctgaag
      601 aaaaattcag taaactatca acaggttctt attttgaaaa aatccattta aatgttacta
      661 acttaacaaa agaacgccaa tttcttaatc atgtacttgg tttgaaggta cataatgaag
      721 aagagggcat ccatgtattg aatgaaggag atttccatgt tggtttgaca gaagctagcg
      781 gaggcgcaat tgatttgcct acagatgaag tgattggact tgattttctg aaattcatga
      841 tcgatactga aagcatggaa ggactgattg ctcacttgca gcaactatca gttgatttct
      901 tcttagacaa aaagcacaca gtactcacaa tctatgatgc tataggaatc gaatggtggt
      961 tcgtcagtga gccaaaagaa aagaataaaa ctgacattcg atgcgacgct taactttttc
     1021 tttcttaacg attgtcgcat gtctcgtcat tttatgaacg gtcatactat cgcttattct
     1081 agagatagaa agagaaaata gtataccggg ggaaactgcg cggtttttcg cgcagttttt
     1141 ttgtgtaaaa aaggttgatt cctcatagat taagctttaa gcttggactg taagaatctg
     1201 atagaaaagc aggagaaaaa gatgtatcca cacacgaaac agcttatttt gaaaaagatg
     1261 gaagaaggat tttatccagg tgtagcagtc gccttcataa aagaaaatca agtagaaaca
     1321 tttacagccg gctttgccca agtcgttcct gaaaagcagc tgatgacaga agatctgttg
     1381 tttgatgcag cctcactgac gaaagtcgtt gcaaccactt cattagtttt acgtctatta
     1441 gaagatggaa agatagaact cgatcaaccg cttcataaat atcttcctga atttgaaaat
     1501 cagacaatca ctttgcgtca tttactgaca catacttctg atatcaaaac atggatacca
     1561 aacagagata agctatctca ggaagaattg atcgccgctt atttgaagct agaaccaggt
     1621 gagcaactag gaaaagaagt aaaatataca gatgccggta cgattcttct tgggttgatg
     1681 ctagaggaaa tttaccaaga aactgcagtg gaaatctttc aagaacaagt attggaacca
     1741 ttaggaatga tgaacagctt atttcttcct tttccttcca aaaaaatcgt tcccacagaa
     1801 caactgcctt cgggtgaggt tttgcgtgga caaactcatg atccgaaagc aagagttttg
     1861 gctgaacatg caggtaacgc gggtctcttt attgatttga aagacagcat tacttttgtc
     1921 caaatgtatt tgaacaaggg aaaaatccgt aatggtcgtt ttttagaaga agagacgatt
     1981 gattctttac tgcaagatca aacaccgaaa aaaaatggct atcgttcttt aggatgggac
     2041 ttaaaaaagg atgtagaaga cggtcatgcg attctttttc atactggtta tacaggtacg
     2101 tttttcttga ttgatataaa aacacaagaa gcgttgatat ttttgtcaaa tcgcgtacat
     2161 cctgtcgatc atcgtgcgga gtatctcata tgtcgagatg aaattgttga aaactttttg
     2221 aaagagaaaa cggtattacc gaaataatgc tataatagct atgaaaaatg agaggagttt
     2281 gaattatgca ggaacctatg tttttaaaac cagtttttca agaaaaaatt tggggaggaa
     2341 gtcgtttacg ttcagtcttt ggttttgata tccctaacga taaaatcgga gaagattggg
     2401 cgatcagtgc gcatcctcat ggtgtcagtg tagtagaaaa tggcgaattc aaagggaaaa
     2461 gattagatga actatggtca gaacacaagg aattgtttgg ccatccttca gaaccagtgt
     2521 ttccattatt gatcaagatc ttagacgcag aagatgatct atctgtacaa gtacatccag
     2581 atgatgccta tgggatgaaa catgaaggtg aattaggaaa aactgaatgc tggtatatca
     2641 tcgatgctga acctggtgca gaaatcatct atggtcatca tgcaaagaca agagaagaac
     2701 tagctgagat gatcaaagat gggcgctggg atgacctttt gaagaaagta ccagttaaaa
     2761 aaggtgattt cttttatgta ccaagcggaa cgatccatgc tattggtaaa ggaatcatga
     2821 ttttagaaac acagcaaagt tctgacacga cttaccgcgt gtatgactac gacagaaaag
     2881 atgcgcaagg acaaacaaga gagctgcata tccaacaatc gatcgatgta acaactgtcc
     2941 ctgcgaaaac accagaatta caaatcaaag aagtccgaaa agggaattca tcgatcgtca
     3001 cttatttaga aactgagttt ttcaatgtat atgagtggga tattaaagga atcacatctt
     3061 tcaaaaaaca agccccttat acattgatga cggtaatcga aggagcagga gaccttgtcg
     3121 ttgacggaaa aacatatcca ttagaaaaag gaacaagctg tattattcca aatggcgttt
     3181 ctgagtgggc ggtccaaggt gaactagcaa tcattgcgac tgaaccaggc aaatagttcc
     3241 cagatagctg aaagcagcag acggtttttc gtttgctgct ttttctacat aaaatccgtc
     3301 catcaataaa tagaagtatg gtgaaaaaga tggaatacaa atggaaagca aacaacagca
     3361 gtcgcgtgtc tatgaaacaa ctgagaaaag ctggacatca cttaaatgaa atgatcatgc
     3421 caaatctaag tctgtttatc gcttggggaa tcttgtcatt agcaacaaaa ggtgtgtctg
     3481 gcgatttgca caccacatta gaagaggtat gccattggat gatccagctg cttttaccca
     3541 tcttgatcag ttattcaggc gggaaatcgg tagggggaca aaaaggggca gtcgccggtg
     3601 caattgcttc tttagggttg atcgctcgtt ccaatgctcc acaaatcgta ggagcgatga
     3661 ttatcgggcc gcttgccggc atcgtatatg aacaatttgt ttctagattc cacgtgaaat
     3721 tcaaggctgg atatgaaatg cttgtcagca acctactagt aggactgact ggtagcgtta
     3781 tttgtataat tggaatcgtt tttattgaac cagttttaaa tagtgttcac ttgttgctcg
     3841 cctccgttgt gtcttggcta gtcacaatga atctgttacc acttgtcagt ctgatcttag
     3901 aacctctaaa agtactattt ttcaataatg caatcaatca tggtgtattg acacctttag
     3961 gaatcgaatt ctcacaaaca gtcgggtact cttccttatt tttgatggag gcaaatcctg
     4021 gacctggttt agggatctta ctttctatcc tttgttttgc agaaaaacag gaaaaagtaa
     4081 atgcgagtgg agcattgatg atccatgcga ttggcgggat tcacgaaatc tattttccat
     4141 ttgtcttgct gcgaccgtat ctatttttag ctgtaatggc tggtggggca agcggcacgt
     4201 tgatatttca atggttagat acgggattag ctgcacctgt atcgcctggg tcactactcg
     4261 tgatttttgc caatgcgcct tatccacaac tagctggggt aagtataggg atagcaatca
     4321 gtacatttgt gaccttcatt tgtgcagcga tactattgaa attaccaaat aaagaaaaag
     4381 agaacaaaac ggtcaaagaa aggggagaaa tcttggaacc atctatcatt cattccgtca
     4441 tttttgcttg cgactcaggt atgggatcaa gtgctatggg agccgccctg ctgaaaaaga
     4501 aattagcagc agaaaaaatc gatctttctg tcggatacag ctctatctat gaattgaata
     4561 accaagtaaa tcagctggtt atcgtgcaac atgaactagc gggtcttgca agagaaaaag
     4621 tacctcaaag tcaaatctat gtactggatc actttttgga aacagatatc ttgctgtcac
     4681 gaataaaaga agcgatccaa tttccaaagc gggaagaaaa aaaagagata gcagatatca
     4741 cagaacaaaa aaagtcgcct gctaatattg tatttttgta taaaaacaac agacgcggct
     4801 cacaaactat gggcatgacg attttaagtc aattagcaaa aaaagcgaaa aaacagtttg
     4861 ttatctcaaa agaatcaata gaaaaaatca aaatccaaga agaaacgatt tatatcgcac
     4921 aaagagaact agctgtaact gaacagctag aagaaaagat ccctcggcta gttctagttg
     4981 aacattgggt agctacgaat gaatacgaaa aactcgtgaa gggagaaata taagatgtat
     5041 ttatcgccca gagaaaaaca attattagca gaatttctca gtagcccgtc acctgtatct
     5101 atccaaaaaa tgatgaattt attgaaggtc agtaaacgga ctatttaccg cgaattagat
     5161 aatcttgaag tctcattgaa atcggtaaat gcttctttga aaaaagcagc tagaggctca
     5221 tttgtcattg aggcatcaga agaagtatta gagcaattaa aagaaaatac agatgggaaa
     5281 agtaatgact tatccactgc taaacgacaa cacgcgattt tagccgagtt gttactgacg
     5341 acagagccgt tgagtcttgc tcatttcatg gaatcatatc gcatcagtaa taccactttt
     5401 tatgcagata tcaaacagtt ggaagaaagt attcgccaac tgcctttgga aatcattcgg
     5461 aaccagggat acgagatcga aggaccggaa aaataccgcc ggcttctgac agcgaatgta
     5521 ttagaattag aaatcaatga atatgaactt tttcatagta tttctttcga tgcatcactg
     5581 aattattttt ttcgattcgt tgatccgcaa catctatctc ttgcacgcaa agtaatcggg
     5641 gaagaattga tccaaaaaaa gaccaatcta agtgatagaa agcttgaaca tttggttttg
     5701 atgctgacat tgacgatgga gcgtgtgact aaaaatcatt tactgacaaa tgagacatat
     5761 aatagtctgg caaacaaaga attactacag acagctaaac gattgttttc acggatcgct
     5821 tctgagacaa aacaacttta tccagtaaat gagatcgtct tttttgcagg attattaaat
     5881 gacttcacga actcatttga tcagaatttc tttgaagaga cgttcgatac acagcttgct
     5941 tatttagtaa aacaactgat tcaagaagta agtgaagaga cgaatgtcca tttttatgaa
     6001 gatgaaactt tgtacaaaat gctgttgact catttatctg gtgtgttttc aagagccgtt
     6061 ttacaagaag agacactgac caatccgatt ttagaaaaaa tcatggttca atacgaggaa
     6121 gttgcgaatg caatccgtaa agcagtagag cggatttttc aagaaaaaaa attatccgaa
     6181 gaagagatcg cttatatggt ccttcatttt gcgaattcat tggaacgaag tccgaaagaa
     6241 agcaatatca gtattgcagg attttcgcca agtggattag cttctactag catgttggaa
     6301 ctacgattga aaaggtattt tcccttcatc caacaaattc atttctatcg gattgctgat
     6361 ttaaaaaaaa tcgatttaca agaagaatat gatgttgtta tttctacatc tattttacca
     6421 ggatacggtg gaaaatatat tttagtctcc ccgctactgc tagaagatga agtcaagcag
     6481 ctaaaagaag ctttttcgca tattgagaag aaaaaaaggc aaaaaattac gtataacagc
     6541 aataacgagt ggatgataga agatacttat gaggaaacaa tgcatttcat ggatcaaatc
     6601 aatcaattac tcggtcgttt ttttatccaa gaactggata atcctgagac gatttccgaa
     6661 acgattcgca gcttatttcc ttattttcct gaaggactag taacggatga agaggtggtt
     6721 catcgccggc tgcttaagcg atatgaacaa gcacctatcg gtattcctca tacaaatatg
     6781 gggttattcc atacatccag ctcattgatt tctaaaccga tcttttgtat tttcaatttg
     6841 aaacatccgt tgaccattga agggatggat agacagccag tcgatttgtc ccgtatgtta
     6901 gttatgctgg cgccttcgcc aatccaagaa aaagacggga ttcttttagg aaagatcagt
     6961 ggagcaatca tcatgaatga cttgaacacc gagatcttcc gctcaggaaa taaagaaatc
     7021 gtttatcagt tgttagcgaa aatcctgatt gaagaaataa agaaatgaag gtgaaaagat
     7081 gatacagcta ccagcagaaa aaatattgct cgatcaatcc tatcaaaatt ggaaagaagc
     7141 gttgaccgag atcggccagt ggatgaccca acaaggggga atcaaaccgg catatatcca
     7201 atcaatgatc gaaagacaag aaaaagcgag tgtctatatc gggaatttcg tagccttgcc
     7261 acatgggact gacaaagatg aagaagtagt agaagaagga atctatttag tccaagtgcc
     7321 tgatggtgtg gactttggaa caaaagagga accaaaaatc gcgacactct tatttgtagt
     7381 ggctttaaaa aaagaacatc agttagcggt gctccaagat ttagcctttt tctgttcaga
     7441 catcgaccaa gtaatggcgc tcagtgatgc gaaaaccatt gaagaagtcc aaatgatttt
     7501 tgaacatgga catatataac caatgttcac agtaaaaaaa gctgccttgc atcaagtaat
     7561 aacttcaacc aagataaaaa taagaggagc tatttttgtt gggaggttct tattactgcg
     7621 gatgcaagct tttgaaaact atttattcta gaaaaccgtt tatttgaaat aggggacggt
     7681 gacaaggttt ttgtcaccgc ccctattatt tttgtgtttt aatagctctt ttttatatag
     7741 atagtgccca tacctatgaa taataaaacg atactccata taccaagtgt caagatacca
     7801 ttcatgaaag taacctgttc tgaagctagt ggcgagaaaa tatctcctcc tatgatcaca
     7861 ttttgaaaat caacataaga agttggcaag taatgactga ttgattctat ccatccaatc
     7921 gaagaaaaca agcgatactc tgctaagaaa agacaaagaa gtgtacctaa aagattgact
     7981 agagaatgtt caaataaagc agatagaaga aaactgattg tacttaaaaa gagcacccac
     8041 aacaacagga acagaaagct ctggaaaaga tactcataca tcggaaggat tcgtatctcc
     8101 tgaccaatga tcgttcctac aggataacgg aagtctccca aaccattttt gattattact
     8161 agtatagaga cgatcaaaaa tggcatcacg agacttagca tagctgcacc ataataaatg
     8221 gtaaaacgga tgctatgttt ctttaccata ctatccggta atagattgac tagagagatt
     8281 acctgctttc ttttttcata agagatgatg gaagaaagaa acaaggcggt tatacataaa
     8341 atcaaaaaac tagaaatcat tcctgaaaaa atattttcgt agtaatttgc taaagggaga
     8401 tgcgctggca agtcaaaaat agaatatctt tggatctgat gttctttcat ataacggagc
     8461 aactcgacac gtttttgttg ttcaatgatt ggaattcctt gtctttgacc agaaatcagt
     8521 cgatccagta tatctttttc ataatgataa gttgcttcga ccatttgctg gacattccct
     8581 gtgttttttg catgtaagat tgcttcgatc agtttgttgc ttttctctaa actttccaca
     8641 aattctttct cattctcatc ttctttcaac gtttcaatca aacgttgcat ctcttcatag
     8701 ttatgattca gttcatcgaa ttctgtataa gcaagtttat gatcaaaaaa aagtgggaat
     8761 gcaaagagca cgaccaacaa tagaggaaat aaaaagttta ctttgttttt tagtaagaga
     8821 ttgcgttcaa atgtaagtaa agacatagtt acacctcata taatttacga taaatagcta
     8881 aaatctcttc catatttgag gattctgtga cgatttctcc attttttaga aaacatgctt
     8941 tagaacaaat cgattggata ttcgcgatag cgtgggaaga aagaagaatc gtcttcccct
     9001 ctttctgcca ttgtctgatg aggctattca agatatcaat acttcctggg tctaatccgt
     9061 tcaacggttc atcgaataac atgacagatg aatcactgat caagtaagca gcaagcaaga
     9121 catgttgttt cattcctaga gacatttttc caatcggcaa agtaaggtac tcagtcatct
     9181 tcaatcgttg gaaaacagtt tggcattcta ctttgctctg ccaatagtat ttgatcaaag
     9241 tcaaataatc aacagccgat agatagtcgg ataactgatt cgttgattct agaaaaaaga
     9301 aagaccggcg ataatctgta taagcagtag gagagatgtt gtgaagggac aattgatcat
     9361 aagttgttgg cagcagttgg gcaatgccat tcagcaaagt tgttttgcca aatccgttcg
     9421 gggcaatcaa agcagctact tctcctgatt ctactaaaag attcaattgt cgaatcacac
     9481 gttttttacc acgtttcatg ttcatgtttt tgatcagtaa tgtcatagat aggcctccaa
     9541 tataaaattt aataacataa tagaatggaa aacatctaaa ttaaatgcta acaaaagtta
     9601 ttgtttgcat attataaaaa aattaaaata acagttttat ttaaaattga agttttctga
     9661 taccgaaatc tttttatttt gctgacatac tcaaaccttt ggcacaaagt ttcgtgccaa
     9721 agtacgacta tttctctttt tagtaagcgg atacaattag agtatcaaaa ggagagaggg
     9781 agagacaaaa tggaacggac gattcccaaa aacaacattt cgctaaaagc gagggtacaa
     9841 aaattaggca gtactttatc aagcatggtc atgccaaata ttggagcact gattgcctgg
     9901 ggtgtattaa cggctctatt tatcccagat ggttatttac caaatgaggc tttggctacc
     9961 atggtaagcc caatgctaac ttatctgatt cctttattga tcggttatac tggcggaaaa
    10021 gtaattgctg gtgaccgcgg atcagttgtt ggggcaattg caacgatggg tgtgattgtc
    10081 ggaacagata ttccaatgat gctaggcgcg atgatcatgg gacctcttgg tggatatgcc
    10141 atcaagaaat ttgatcagct attccaaaaa cggatcaaat ccggttttga aatgctagtc
    10201 aatatttttt cagcaggtct tatcggtttt ggattagcgt tattaggttt ttctgcgatt
    10261 ggtccagttg tcgatgcatt gactcaagca atggcaaaag gtgtagagat cattttatct
    10321 gcccatttga ttccattgac aagtattttt attgaaccag caaaaatctt atttttgaat
    10381 aatgcaatca atcatgggat tttgacacca ttgggaactg aacaagtagc agaggctgga
    10441 aaatctattc tattcttgct tgaagcaaat cctggtccag gacttggcgt attacttgct
    10501 tttactttgt ttggcaaagg agcagcaaaa tcttcagcac caggagccat gatcattcac
    10561 tttttaggcg ggatccatga aatctatttt ccttacgtta tgatgaaacc gttattattc
    10621 ttatcagtta taggcggagg aatgtcagga agtttcattt tccaattgat ggatgctgga
    10681 ctaagagcgc cagcttctcc agggtcgatc attgcgattc tagcgatgac accgttcaat
    10741 tcttaccttc ctgttatttt gggcgtgatt gttgccgcag ctgtttcgtt tggtatttct
    10801 gcagtaattt tgaaagcgga tgcgaaagat acaaatgaag acttcgaaaa atctgttcaa
    10861 gagacaaagg cagctaagca agcttccaaa ggtgcccaag gtattcctca aggagctaca
    10921 ttctctggcg tacaaaaaat catttttgct tgtgatgcag gaatgggatc aagtgcgatg
    10981 ggcgcttcga tcttgagaaa aaaagtacag gaagcagact tgcctcaaac ggtgaccaat
    11041 caagcaatca gccaactgac agatgactcg aatacattga tcgttactca ggtcgaacta
    11101 caagaaagag caaaacaaaa agcaccgagc gcgcgttttg tctcagtaga aaactttttg
    11161 aattcacctc gatatgatga aatcattcaa gaattaagca gcaagcagaa aacatcagtt
    11221 tctgaaattg agaatgagcc agcagaagag tttctttcag caaacatcaa acaaatcaaa
    11281 gagattctac ttgtccacga tgatcgttcc ggatcagcaa caatggggat gaccgtgctc
    11341 aaagatatat tagacaagaa ccatttaact atcccgttaa gaaaagtcaa tatccaagat
    11401 ttaaaagatg aacctgattc actgatcgta gccaaagaaa gtttagcgga aaaagtacag
    11461 atggctgcac ctcaatccat tcatttatca gtcaacagca tggtcaatcc gcaaaaatac
    11521 gaatcgattg cacaatattt gaaacagaca gcttaaggga ggaaaacagc atgcaaagtt
    11581 tgccattcga catgatcgag ctcaatcgat cttttaaaac caaagaagaa gcgatccgct
    11641 attgcggtca gatgcttgta gaagcagggt gcgttgatga ggaatatatc gatgccatgg
    11701 tagatagaga caaaatgtta tctgtttata tggggaattt tatcgcgatt cctcatggaa
    11761 cagatgaagc aaaaaaatat gtgaaaaaat ccggcatctg tgtcgttcaa gtaccagatg
    11821 gtgtagattt tggtaccgaa gaagaagaaa agattgcgac tgttttgttc ggtattgcag
    11881 gagtcggaga tgagcatttg caacttgtac agcaaatcgc actttattgc agtgatatgg
    11941 acaatgttgt ccagctagca gacgcgctca gcaaagaaga agtaacggaa aatctagcaa
    12001 ttgcttaagg agagagaaaa atgagagcag tacattttgg tgcaggaaat atcggtcgag
    12061 gatttattgg agaggttttg gcagctaatg gatttgagat tactttcgta gatgtgaatc
    12121 acacgatcat tgatgcttta aatgaaagaa aagaatacga aatcgaatta gcagatgaat
    12181 caaaagaaaa aatcactgta aaaaatgtca aaggaatcaa caatcaaaca aatccagaaa
    12241 aagtaatcca agaaatcgct gaagcagatt tagttactac cgccattggc ccgaatatct
    12301 taccttttat tgctgagttg attgcaaaag gtatccaaga aagagaaaag gaaggaagca
    12361 caacatcttt agatatcatt gcctgtgaaa atatgattgg cggttcagca tttctagaaa
    12421 aagaagtgta taaatatctt ccggaaacat catttactga caaatatatc ggctttccaa
    12481 atgcagcagt cgatcgaatc gtcccattac aacaccatga agatccttta ttcgtccaag
    12541 tggaaccttt caaagaatgg gtcattgacg atagccaaag aaaaaataaa aaaatccaat
    12601 taaaaggggt tttatatgta gatgatctag aaccatatat cgaacgcaaa ctatttagtg
    12661 tcaatactgg tcatgcgact gtcgcttata caggtgcctt gttaggttac cagaccattg
    12721 atgaagcaat gcaagatgcg ttagttgtgg cacaattaaa atcagttttg caggaaacag
    12781 gaagtttgct gattgccaaa tgggggtttg atgcagagca gcatcatgcg tatattgaaa
    12841 aaatcattca tcgcttccaa aacaaaaata tctctgatgc gatcacacgt gtcgctcgga
    12901 caccattacg taagttaggt tatcaagaaa gatttacacg tccagtgaga gaactacaag
    12961 aacataactt gacttgccca catttgacgg caacaatggg gattattttt aattactatg
    13021 atcctgaaga tgaacaaagc cgtcaattgc atgaaatgaa gatccatgaa aacttggaac
    13081 aattgattca agaagtcaca ggaatcaatg atccgaaaac aatcgggaat atcaagcaaa
    13141 acgtgaaccg ttatgccaag caagtcgctt aaaataggat acgaaaaagg ggaatgtgac
    13201 gaaatttt
//
LOCUS       DAFKHN010000069        13086 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFKHN010000069 DAFKHN010000000
VERSION     DAFKHN010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.069"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(79..2199)
                     /locus_tag="LY912_002132"
     CDS             complement(79..2199)
                     /locus_tag="LY912_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBM6955790.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2429..3607
                     /locus_tag="LY912_002133"
     CDS             2429..3607
                     /locus_tag="LY912_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBM6955791.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3623..4381
                     /gene="aroD"
                     /locus_tag="LY912_002134"
     CDS             3623..4381
                     /gene="aroD"
                     /locus_tag="LY912_002134"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBM6955792.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4404..4889
                     /gene="ybaK"
                     /locus_tag="LY912_002135"
     CDS             4404..4889
                     /gene="ybaK"
                     /locus_tag="LY912_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBM6955793.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4960..6213)
                     /locus_tag="LY912_002136"
     CDS             complement(4960..6213)
                     /locus_tag="LY912_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBM6955794.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6329..7678
                     /gene="gdhA"
                     /locus_tag="LY912_002137"
     CDS             6329..7678
                     /gene="gdhA"
                     /locus_tag="LY912_002137"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBM6955795.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7790..9136
                     /locus_tag="LY912_002138"
     CDS             7790..9136
                     /locus_tag="LY912_002138"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBM6955796.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9444..9830)
                     /locus_tag="LY912_002139"
     CDS             complement(9444..9830)
                     /locus_tag="LY912_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBM6955797.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10098..10247)
                     /locus_tag="LY912_002140"
     CDS             complement(10098..10247)
                     /locus_tag="LY912_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955798.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10709..10921
                     /locus_tag="LY912_002141"
     CDS             10709..10921
                     /locus_tag="LY912_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955799.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11199..12998)
                     /locus_tag="LY912_002142"
     CDS             complement(11199..12998)
                     /locus_tag="LY912_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBM6955800.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2354 c         2577 g         3864 t
ORIGIN      
        1 ttattctaag atttctcttt accaacatca tttgacaaag agcctaattt tgtcgctgct
       61 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
      121 cgtttgcgtt ttataaagat caacagttga ttgtcccttg tgttcactaa agacactagt
      181 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
      241 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
      301 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
      361 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
      421 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
      481 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
      541 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
      601 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
      661 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
      721 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
      781 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
      841 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
      901 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
      961 ttgcagacgt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     1021 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     1081 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     1141 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     1201 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     1261 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     1321 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcaagctgga gaccattctc
     1381 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     1441 attttttcct ttagcgagcc cgaacaaatc atcatttggt gctgcataat gttcttttac
     1501 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     1561 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     1621 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     1681 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     1741 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     1801 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     1861 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     1921 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     1981 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     2041 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     2101 taaataggca aaaatcgttt tcaaccaaag taaaacaact agtaaagaaa aaaatccgag
     2161 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     2221 tcttaatcac agaagtgtca tgaaaccatg ttacacagct cacttattct catttatttt
     2281 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     2341 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     2401 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     2461 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     2521 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     2581 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     2641 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     2701 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     2761 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     2821 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcgtag gaggctatga
     2881 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     2941 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     3001 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     3061 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     3121 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     3181 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     3241 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     3301 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     3361 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     3421 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     3481 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     3541 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     3601 ccattagaag gagcgatgca gaatggtttg ggtaaaggga ttgaatatag gaagcggtag
     3661 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     3721 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     3781 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     3841 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     3901 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     3961 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     4021 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
     4081 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
     4141 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
     4201 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggctgg
     4261 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
     4321 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
     4381 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
     4441 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
     4501 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcat atatttaaaa
     4561 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
     4621 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
     4681 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
     4741 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
     4801 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
     4861 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
     4921 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
     4981 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
     5041 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
     5101 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
     5161 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
     5221 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
     5281 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
     5341 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
     5401 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
     5461 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
     5521 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
     5581 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
     5641 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
     5701 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
     5761 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
     5821 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
     5881 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
     5941 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
     6001 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
     6061 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
     6121 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
     6181 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
     6241 atctgaagaa agaaaacaga aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
     6301 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
     6361 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
     6421 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
     6481 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
     6541 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
     6601 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
     6661 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
     6721 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
     6781 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
     6841 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
     6901 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
     6961 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
     7021 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
     7081 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
     7141 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
     7201 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
     7261 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
     7321 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
     7381 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
     7441 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgcccagcg
     7501 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
     7561 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
     7621 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
     7681 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
     7741 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
     7801 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
     7861 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
     7921 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
     7981 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
     8041 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
     8101 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
     8161 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
     8221 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
     8281 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
     8341 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
     8401 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
     8461 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
     8521 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
     8581 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
     8641 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
     8701 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
     8761 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
     8821 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
     8881 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
     8941 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
     9001 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
     9061 caagaaaaac atgttcgcac ttctaggcaa accgggcttt gaagatcttg ctaaagaatt
     9121 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
     9181 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
     9241 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
     9301 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
     9361 ggttaattct gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg
     9421 cttttttgcg atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt
     9481 accttatcgc tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc
     9541 aagatcgttc cttcggtgta agcagaacca ttggcagagt caccagaagt aatgacatcg
     9601 aaatctaact gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct
     9661 cttccaatta cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg
     9721 actaccgcat aataatcttt acctacataa gtagactgat agtagtccca acctttccat
     9781 cctataaaag caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc
     9841 cttttttatt tttattatat taaatattat acagataata acggaatatt atcatcgaaa
     9901 cagctaacaa aattgtcata aaaaacgaga tggttgatat tagaacttgt gtttttgttt
     9961 aggtctagag ataaagagag acaatttcca aatatatgta atgaatacaa aaagacgttt
    10021 gtcgcggatt accgttacaa acgtctttta ttgattttcc gagatctcat cagtcgccat
    10081 ttggaatggt tcactcctta tctagattcg tttaatgctc ggactgcttg ttcgattgta
    10141 ataccaaacg caacgttatt ttcgttttgt gcatcaatcg ccataaaacg gttagaagtt
    10201 gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa acgtcataaa attcatctcc
    10261 tttgtaatgt aatttagttc ttgaaagttt cctttaaact ttcgaactta taccaagttt
    10321 agcatcgtac gttttttgat gcaattaaaa agcatttatc attttcctta tttatttttt
    10381 cttaaatggt ttagctattt tcttttaatc cgataagtag cccaatcatc aaggttacaa
    10441 atactattgc ttgaatataa atcatatgct cacctcttta taaataactt agcaatataa
    10501 agaaaaaaac gcacgaacaa cataggaata taaacaaacg tttttgtcac aacgtctaag
    10561 atcgtgttaa aaaatagtta tctaaaaagc agaaagatac tcaaaataaa aaataaaaaa
    10621 atgaataaaa acgttttcaa atacaaggta atttgttatt ataaaataaa gaaaaaacaa
    10681 aataaaaata aagaaaagag ggaatgaaat ggtaaaagca gaagtaggaa gatcttatat
    10741 atgcaaaccg atcggagtat ctcatgaact aatcggctgt attgaacgta catatatcaa
    10801 cacggctgtc gtgtatgttg aaagttatga ccaacgagac tatcaactta tcaatgaaag
    10861 caagtatcgc atgctcgtaa aattctgtga tattagcgca cctactgaat tggtttctta
    10921 aacagtattt ttgagaattc gcaagaactc ccttataata taaataaaga cagaagggag
    10981 cgagaagata tgccaaaaag aaaaagttca gggaaaatgg gaattattct tgcagtgatc
    11041 tctgcaattc ctgctatttt agctattgtt cgtgcgatga aggaatcaag agaaagttaa
    11101 gcacacatta tgagcgtcaa acaaaaaacg catatacctg cggtggcagg ttatgcgttt
    11161 tttgttgtat aaagactttt ttcattaacg atttttgatt agccgactcc caaaacaaaa
    11221 tttagcagtt tatctgaata agtgatttct tcatctgttt gtttcacact ttcatttagt
    11281 agtcccatct catcggttat gataccatcc acaccataaa acatcatgcg actcatggca
    11341 tctgaatcgt tgattgtcca tacatatact tcttttccgt cttggtgggc agaattaatg
    11401 aagttacggt tgatcgtact atattccatt gtcagaaaat cagcaggcgt cacagggggc
    11461 ccaacaatat tgaaaggtaa gatgtagccc acataaaagt ttggttctgc ttcttttaaa
    11521 tctgaaacgg tttggtacgt caaactttgc aaaatatgat ggttctctaa gataactttg
    11581 cggtatttat ggacaaatcg ttcgacaagg tcatccgaat cttttttaga ggtcttgatc
    11641 tcaataagta atttttggtt tagcttatgt gctttttcca aataagaatc aaaagaacaa
    11701 acaggggctt gcactccgtt ttcagtaact gtaagatttg tcaattcttt caatgtaaga
    11761 tcctgtggtg ttccatttac ccctgttaag tgacgaagat ttgcatcatg catcactacg
    11821 aaatgaccat cttttgtttc ctgaacatcc atctctacat aatcaggatg atagtctctg
    11881 cttgtttttt caagtgcttc taaagtattt tgcgccccat tttgggtact cacacctctg
    11941 tgagagacag tcactggttt tgtctgaaca gctgaagtca gataatccat attgtaaaga
    12001 cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac cagtgttttt cagcgcagag
    12061 aaacgcaagt tgggggcttg tgggataaac cacttaggga tctcaggcaa gaagccttcg
    12121 tcatccatga aatcaacaat gatataaaaa atccctacgg tagacatcac gatattgaat
    12181 aataaaatcc cttgtaaaag cgtcatagca aacacagcgc tgatcaatgc atagtctggg
    12241 aaaaattgtt caaccatact ttgtgccaaa ataacaacga tatatcctaa agaagaaagg
    12301 agtaaaatcg taccgccaat cacaataaat tggcccgtga tggccaaaag acgcgatttg
    12361 gtcaatgacc agctttcccg aatggctgct cgaaaagaac gatctcgtag aatcatttcc
    12421 ggtaaagcaa aaatcagtcg aatcccaata tagccaagga aaatataaac gagtaaaaag
    12481 gaactgacga tgatccaacg attagcaaaa ataaaatcca taatgaaagc ggggattttt
    12541 atttttgaca gtagatcaga attaaaactt aatccgctga tcggtagaat caataaaaaa
    12601 taagcaagga aaaacaaaaa agtaatgggt ctcactttct tcagctgaag tatcgtcaag
    12661 tgtaagagtt gcttcaaaga gattggttct ttctttttaa taaaaaaaac actcatcaaa
    12721 agaaaagtaa attcgaaata aactaacagt aaaatcgtca tcaaaactac gattaacgag
    12781 agtagaaccc caggatgttg agaaaaaatt gaaggaatat tgtcataaga caaatagtca
    12841 attgcccctc ggtgtaaaat aaaacgggtc gtactgctca ataagggtaa acaaataaat
    12901 aaaataaagc catgcatcag caagacatca cggaaataag cttgtgttcc ttttaaaaag
    12961 tcccaagcat tacctaagct acgtttcaaa taattcatcc tatcacctgc tcttcacatt
    13021 gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt tttgcagacc ctttcccaga
    13081 tttaac
//
LOCUS       DAFKHN010000070        12794 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFKHN010000070 DAFKHN010000000
VERSION     DAFKHN010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.070"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(81..860)
                     /locus_tag="LY912_002143"
     CDS             complement(81..860)
                     /locus_tag="LY912_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955801.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            complement(1250..3325)
                     /locus_tag="LY912_002144"
     CDS             complement(1250..3325)
                     /locus_tag="LY912_002144"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBM6955802.1"
                     /translation="MAKDLLLEIGLEEIPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKQYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(3327..4244)
                     /gene="glyQ"
                     /locus_tag="LY912_002145"
     CDS             complement(3327..4244)
                     /gene="glyQ"
                     /locus_tag="LY912_002145"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBM6955803.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(4628..5440)
                     /gene="recO"
                     /locus_tag="LY912_002146"
     CDS             complement(4628..5440)
                     /gene="recO"
                     /locus_tag="LY912_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBM6955804.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(5583..6482)
                     /gene="era"
                     /locus_tag="LY912_002147"
     CDS             complement(5583..6482)
                     /gene="era"
                     /locus_tag="LY912_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBM6955805.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(6497..6892)
                     /locus_tag="LY912_002148"
     CDS             complement(6497..6892)
                     /locus_tag="LY912_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBM6955806.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(6876..7352)
                     /gene="ybeY"
                     /locus_tag="LY912_002149"
     CDS             complement(6876..7352)
                     /gene="ybeY"
                     /locus_tag="LY912_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBM6955807.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(7369..9561)
                     /locus_tag="LY912_002150"
     CDS             complement(7369..9561)
                     /locus_tag="LY912_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBM6955808.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(9585..10556)
                     /locus_tag="LY912_002151"
     CDS             complement(9585..10556)
                     /locus_tag="LY912_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBM6955809.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            11262..12641
                     /gene="brnQ"
                     /locus_tag="LY912_002152"
     CDS             11262..12641
                     /gene="brnQ"
                     /locus_tag="LY912_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBM6955810.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3479 a         2654 c         2317 g         4344 t
ORIGIN      
        1 tttttccctc ttgattttct tcttcgtctt gccatagttt cctccgtttg ctaaccttgc
       61 ttgaatcaac gttttaactg tcaataactt atattgctat agcccatttg ctgagcaaca
      121 gtttgtgctt ttgttgcgta tgctgcgctt attttttcat tccggatctg ctctatttga
      181 ctgagcgccg tcaaatattg atcgtaagta gcggtggcag tcacttgacc atccttcaac
      241 atcgtatcga ataactgatc tagttgcgtg acttgcgcga tctgagtatc agcgaatcct
      301 agatattgca taacaaccgt tttccaagga ctatctttaa aaaagctcat attttcacgt
      361 acacgagcga catctgcact tgtcaccttt tctttgatga cgacatcgtc tacagcttgc
      421 tgccagtttg atacattttt agtaaataaa tcgttgacag ctgtctggat cttcagtttt
      481 gattctgcac tatctaactg tgtcacgatt gctttcttct catcttggat tgcaacagct
      541 tctttaggca attctgattc tttgatgtcg taatcatctg ctgaaagttt gacagaggat
      601 agcttatttg acaaacttgt gattgtttct tctgttattt cagggtttag aaaatttttt
      661 tcttttgtac tatacagctt gtctacttct tttgataaag aagtcaaggt gtctttttga
      721 ttggtgatgg cagattctgc ataattgatc cgttgctgat gttgccgctg attattgata
      781 tggtaaccaa acaaacagat cgcaatagca cctgcaccta ccgccacagc agtcaatgac
      841 ttgacgaatg gcttttccat agattcactc ctaagtattg atgatagata aattaagata
      901 taattcacat acataaaaat gacagctttt tattttaaaa aacataatta aattaatata
      961 ttcacagaaa tatttgtaaa caagttttcc ctatataatc ataccacaaa ttgttttctt
     1021 gactagggca atttacgatt taaaagtaaa taaaacatta ataagataac aattaatcga
     1081 tttcattttt atttccttaa ttttcatagg tgtttttaaa agttacacaa aaaataaaat
     1141 aacaaaaaaa ttaacattga attaataata gttatttata tttataacaa ataaaccaga
     1201 gaaatagcct attttgtgcc tgttctctgg tttatttaca tattagaaat tattttgtga
     1261 tgatttgatc taaacttgct agtgacaaag ccatggcagc aatttgactt aattgcgtta
     1321 atcggttctt acgtactgct ggttcttctg ccatgaccat cgtctgatca aaataatttt
     1381 cgatcagtgg gcgaaggctt acaagctgat cataattttc gttgatcgtt tggtcagcaa
     1441 agcttgtttt cattgcctct actgctttgt gcagttcttt ctccgcttcg ttttcgaaca
     1501 gttcagggtc tacttctgat tgtttttcaa gctccgcttt tttcgctaag ttcacgacac
     1561 gtgtcaaagc ttccatcgat ggtttgaagt cttcatctgc aagatgctgc ttgaacaatt
     1621 gtgctgctgc aaatactttt gtcagatctt tttgttctgc attcaaaaca gcttcgatga
     1681 catcatgacg gatattcttc gttgtcaata attggcgcag acggcctttg ataaagtcga
     1741 tcacctgttg ttgtcccgct gacaagccaa tgccaaaacg atccgtatct ttactgataa
     1801 cttcactaat cgtttcttgc agaacagaca aaggaaaggc ccattttttc gattcgatga
     1861 ttcgaacgac accatatgct tgacggcgca aagcatatgg atcgtttgag ccacttggga
     1921 tcatcccaac tgcaaagaaa gaaaagatac tatctaattt atcagcaatc gctaaaacag
     1981 aacctactgt agtctcaggt aaatctcctt cactggatat aggcatgtaa tgttcacgga
     2041 tcgctgttgc tacggctggt ttctcgcctt taagcagagc atatttttcg cccatgatcc
     2101 cttgtagttc agggaattct cctaccatgt tggttactag atcaaattta tagatttcag
     2161 cagcgcgttg cagatccatc aattcttcct cagatagtcc tacttgttcg cctatgatgc
     2221 gagcgatgac ttgtacccgt tgcattttct catagatgct accgattttt tcatggaaag
     2281 taacagtttt taatttttca acgtattggt cgattgaagc tttcttgtct tcattataaa
     2341 agaattccgc atcttctaaa cgagcagtca atactttttg attgcctcgt accacatttt
     2401 ccaattttac ccgatcgcca ttacgagcag aaataaaatg aggaagcaac ataccttgat
     2461 cgttccgtac ttcgaaataa cgttgatgtt ctttcataga agtgactagt acttcttcag
     2521 gaacagatag atatttttct tcgaagtcgc cagaaaagac agttggatat tcgactaaat
     2581 tgttgacttc ttctagtaaa tcttcatcta gatcaatgat ccagtgattt ttttctgcta
     2641 attcgtttgc ttgtgtgatg atcatttctt ttcttttttg cggtgaagca ataacaaatt
     2701 gttcattcaa tttttcttcg tattgttttg catgcgtaaa tgtcacatct tcgcctaaga
     2761 aacgatgacc tcttgaagct ctgtctgttt tgacatccaa gatctcaaac gggattattt
     2821 cgtcatctaa caatgccacg atccagtgaa tagggcgaat atattcaaaa tcgtattctg
     2881 cccagtgcat cgttactggg aaagtgaggc ttttaatgac atctgctaaa cctgtcaata
     2941 cttcttttgc ttctttgccg tgagtgtatt tcgttacata gacatattcc acgcctttta
     3001 attctctaaa agtgatagca tctgtcgtca gaccttgtcc gcggacaaat ccttcagctg
     3061 ctttcgtcca gtttccatct gcgtccaaag caattttttt ggctggtcct ttgacttctt
     3121 cttcgctgtc tgcttgacgt tctggaatgt ttgttacttt gattgctaag cggcgcggtg
     3181 tagaaaacgt ttcgatcgta tcataagtca attggttttc atctaaaaat tttgctgttt
     3241 tttcttctaa ttgtttcatg cttggtgtga ctacatgagc aggtatttct tccagcccga
     3301 tttcaagtaa taagtctttt gccatcttat tcagcctcct tcacgttttc tggatttgct
     3361 gtgtttttat tcaataaagg gaatcctaat ttttcgcgtt ctgccacaaa gattttggct
     3421 acagcacgag ccatgttgcg gatacgggaa agataacctg cacgctctgt tacggatact
     3481 gcaccgcgag catctaataa attgaatgta tggctacatt tcaaaatata atcatacgct
     3541 ggatgaacaa gattttcatc gatacagcgt ttagcttctt tttcaaaacg atcaaaattg
     3601 cttagtagca ggtcttggtc gcttacttca aaagaatatt tagaatgttc atattctggt
     3661 tgtttgaaga tctcaccata tttcacgcca tcagcccatt ccagatcata aacactttca
     3721 acttcttgga tataagaagc aagacgttct agtccataag tgatctcaga agtaactggt
     3781 ttacaaggta gtcctccgac ttgctggaag tatgtgaatt gtgtgatctc catcccatca
     3841 agccatactt cccagcccac accggcacaa cccatcgatg ggttctccca gttgtcttca
     3901 acaaagcgaa tatcgtgttc taatggatca attcctaaaa gacgcaagct ttctaaataa
     3961 agctcttgga tattttcagg tgaaggtttc attacgactt gaaattgatg atgctgatac
     4021 aaacggtttg ggttttctcc ataacgcccg tcagctggtc ggcgggatgg ctctacataa
     4081 gcagcattcc atggttccgg tccgattgcc cgtaagaatg tatatgggct catcgtacct
     4141 gctccttttt ctgtatcata agcttgcatc agcatgcagc cgtttgatga ccaaaatttt
     4201 tgtaatgtta aaatcatatc ttggacggtc aattttttac tcatctgttt tgcccctttc
     4261 aatttttaag cgttgctgtc aataagaata caggaaagaa aacgacaaaa agtccctatg
     4321 tctgattaca gacataggga cgaataattt cgcggttcca ccctacttcc gaataaagat
     4381 tcggcagctt catttatcgt actcgcaagt gcctcttcaa aaatcgtttg ggtccggctt
     4441 ccactctccc gaactcgcta aaccacgtgt tttttactga tcttggtcaa tgtacgtatt
     4501 cattttgcag ttttctggtt tgtataatag atcctctcag tgaacgatct atttaatcta
     4561 cggttaataa tagacggaag tccctgtatt tgtcaaatag ttttgatttt tttgttgtat
     4621 ctttcattta ttcttctttt tcaggtatct ctttttcagg catatttttc tctggcgtct
     4681 ttaatacgtg tgcccaagac ttcatttgat caatgaactt tttgcttttt agatgaatac
     4741 cgacatattc atcatacaac tggtcaatga ggtcacggat tgcctgcttc gtttcttctt
     4801 tcaagtggat tccactgatc ttatcataag aaatagccga aaacattcga acgaaataaa
     4861 cagcgcgagg atctgcatga taacggtgtt cgtccattgg ccagtgtttc tcgcatatca
     4921 caccgccata tttggaagaa tagtcaaatt ttccttttgt ttccccgcat acgacacagt
     4981 gcgtccaaat tggcgcgatt ccgaagcgtt gcagtatttg cacttcaaag atattcgtga
     5041 tgatttctgc atcatctcct tggtccatcc gctgcagagc ttgttgcgta aattggaata
     5101 aatgcgggtc atattgatga tcttcgattg ctgcatctac tagatttagc aaatacgtac
     5161 cataaccgct caaaaagata tcttcttgga tgttccgaaa cgcatggacg tctttgacac
     5221 tgcttaaaaa cgacaaacct tcacttcgaa aattaccgat atagactgct tcggtaaagg
     5281 ggagcaaagc cggagctaat ggctgatttt gccgatggat tcctttgata taaaacatca
     5341 ttttgccaga agattccgta aagattttga ctaatttatc tttttctttg taattacggc
     5401 tagataaaat caagcctttc gattctgcaa gctggctcat attctccctc ctaaaaaata
     5461 aatctggaaa agcagattct gccgatccag attatttatg tttcgatctt ccgctgtttt
     5521 tctcaacgta cggattttta tccagtttat ttctatacct aacctataag aagtccagaa
     5581 tatcagtact cgtcttttcg gtagccgaag tcttgcagat agactttttt gtctcgccag
     5641 tctttttgga ctttgaccca aagttctaga aatactttgt ctcctaaaag attttcgata
     5701 tcctttcttg ctttcgttcc tacttgcttc agcatttttc cgcctttgcc gataatgatt
     5761 cctttttggc tatctctttc gacgatgatc gtggcctgga tatggatttt atcattctcg
     5821 tttcgcttca tcgaatcaac aacgactgcg acagaatgag gcacttcgtc tcgtgttaaa
     5881 aacaagactt tctcacggat caattcagaa acgatgaagt attcaggatg atcagtcact
     5941 tgatcatctg gaaaatattg tgggccctct ggcatttcac tgactaatac atccattaag
     6001 cgttcgacat tgtttccttc tgtagcagag atcggaatca cttgtgcaaa aggcatctgc
     6061 gtcgaataat cttcgatgat tcccagcaac tcgtctggat ggatcttatc gattttattg
     6121 ataatcagat aaacaggaga atgcacgttt tttagacgtt caataataaa atcgtctccc
     6181 cggccacgtt tttgatcagc actgatcata aataagactg catccacttc tttcaacgca
     6241 ctgtaagctg cttctaccat aaaatctcct agacgatgct ttggtttatg gattcctggt
     6301 gtatcgataa aaatcagctg agcttctggt gtagtatata ctccttggat tttatttcta
     6361 gttgtctgtg ccttgtcact cataatggca attttttgac ccacgattcg gttcaataat
     6421 gtggattttc ctacattcgg gcggccgacg attgcgacaa accctgattt atgttctggc
     6481 atatacgttc tcctttttaa ttaaacaaca aatgatatat tttagggaca aataaaatca
     6541 acccaatgat gacagcaaaa caagcggtca ctaaaactgc tccagctgcc atatctttga
     6601 tttttttccc aatcggatga aaatgaaaat ccgtaaacat gtccactaca ttttcaaaaa
     6661 cagtattgat gatctctact atccaaacga gaaaaacagc taaaagcagc cataaccact
     6721 ctatccgatc aagctggaaa atcacgccca taaataaagc aaggataccg aacgcaacat
     6781 gtttcctcat attgcgttct tcctcaaaaa cggttttgac tccttggaca gcaaattcca
     6841 cagacatcag gaaatgtttg tttttctcta cgtttttatc ttttgagtcc ataggcatcc
     6901 aagatctctt tctgtaaacc aaacatttct ttctcatctt ctggtgtcat atggtcatac
     6961 ccgttgatat gcaagaatcc atgtaccgct aaaaagccaa gttcccgatc atatgaatgg
     7021 ccgtaagctt ctgcttgttc agcagcacgt tcaatagaga tcatgatgtc tcctagtaca
     7081 cgaggtaatg gattctctcc atcttcaaaa atcactggga tttcgtcttc gccttcttct
     7141 tccagagcaa aactgatgac gtctgtcggt gcatcttttc cacggtaatc acgattgatt
     7201 acttggattg ccgcattgtc catgaaagta acagacattt ctgtttcctc tggcagcttt
     7261 aaataagatg ctgcaaattg cagcaagtca tcgatttctt tcattttctc ttctgagact
     7321 tggtttgttt catccataaa ggtaatatcc attatacatc gcttctttct attcttcttg
     7381 ttcttccttt atcttctcaa cttctgtttt cattttagga tatttgatcc gagaatggaa
     7441 ggtgctactt aaaccgctga ttaatgattt ttccactttt cggatttctt tcaaggtcag
     7501 tccactatcg tctaattgac catcggaaat acgctcttcg ataagattat ggacaaaact
     7561 ttcgattttt tcgctcgtcg gatgatccat tgcccgtact gcagcctcac aactgtcagc
     7621 aatattgacg atccctgctt cacgactttg cggttttggt ccaggataac ggaattgctc
     7681 ttctgttact tccggattgc gttctttcgc tttgatgtag aaataacgca ttagcgtggt
     7741 tccatgatgc tgtttgcaaa tatcgatcac catttgcggc atattataat cttccaatat
     7801 tttggctcca tctgtcacat gtccaaagat aatatgttta ctgtcttctg gcaataagaa
     7861 attgtgcggg ttttccgctc ctgaaggcaa gttttcaacg aaaaagctag catgtttgat
     7921 cttgccgata tcatgataat agcaagctac tcgagttagc aaagaacgtc cgccgatttc
     7981 tgctacagcg ttagcactta gattagctac catcatacta tgatgataag tacctggcgc
     8041 ttcttccagc aactgtttca ataaaggatg atttggattg ctgagttcat ttaatacaat
     8101 tacactgtca tcattgacca tcaattcaat atatgggtgt agaccgatcg tcagcaagaa
     8161 tgagaagagt gcaccagtga acccgcagac gagcattaac caagtcgttg catcaccaaa
     8221 gctcattcct tgatagacga tcaaaatgac atccatcatc acaggaaaaa taatgaccca
     8281 catggcagca gataatcctt gttctgagat ccgtttgcgt ctgacaatcg ttgccatgag
     8341 cccagagaaa acataagaca tcaagataat cgttagaaag ttcgtgccaa tcgaatcata
     8401 aaaaatgaaa agtgcggata ctgcttggaa aataccagcc atgatccctg ctcttcgatt
     8461 caagaaaaag cttaaaacaa gtggtgcaaa agcagcggga taaaacagcg ggatataagt
     8521 agcttgttcc gtttggaata attggaaaaa tttcatcagc actatgctga ctgacatagc
     8581 tgtcacatag aaaagcacgt attttgttct ttctcctgca ttttggaatt gaagtgaatt
     8641 ataaatcagt acgccgattt gaagcaaaac agctaaaacc atggcaatta gcggaaaaat
     8701 cgaagttgtt tgattagtca gtcctagtaa ttccaatttt ttcatagctg aagcatcgat
     8761 ttgattacct tcacgaacaa tgatttctcc ttggaagatc atcactggtt gtacagcttc
     8821 tcgtgcggat tgtttcaatt cttctgtctt tttctcattc aatacgtcat tcactacgat
     8881 accttgatcc actaagtagc gaatcatttg ttgttgtgct ggtgtgacat tcaaatattg
     8941 gatttgctct tctgcttctt gtttaaaagc ttccaattca ctttcacgaa cttgtttgct
     9001 catctgttcg tcaatgagct tcagactctc atccctcaca gtatgaatct cagtttcagt
     9061 catttcaaat atcgtcgaat aaaaattgtt cggtagtttt tgataaaaca caacattttc
     9121 tgcattcaca ttttcaaaat ttttcttcag cgcggcgatc cgctcttctg tagtaggctt
     9181 tgggatattt tcatcttcct ttgccttatc aatcttttcg tcataagatt tgttgatggc
     9241 atcattcgtc ttatcgatca attcaaatag ttgcttgatc cgattgttct ggtcatctgc
     9301 aagatctttt tggtaagtgt attctggagt gactgcttct gctgccagtt ttcttttttg
     9361 ttcggtttct tccgtgttct cgatcgtttt gttcgcacgg atactttctt ctgctacttg
     9421 gccttctctg aaatcattgg ccttttgttt gacactacta aatgtaacgc cgcagataat
     9481 gataaaaaac aagaacagca ggaaaggcaa tgctgccttt ccaagttttt cttgtagttt
     9541 ctgcagtgtt ttattcaaca tgtgcttatc ctcctaagca aagcttattc ttgatggaga
     9601 tctgcctttt cataagcttt gatgatttcg gcaactacag ggtgccgaac aacgtcactt
     9661 gcttcaaaat taacaaaatc gattttcttg atttgcttta atgttcgttc tgcatgaaca
     9721 agaccacttg tcgtccctcg aggcaagtct atctgacttg tatccccatt gacaatcatt
     9781 tttgattgat aaccgagacg ggtcaagaac attttcatct gagcgactgt cgtgttttgt
     9841 gcttcgtcca agataacgaa tgcatcatcc aatgttcgcc cccgcatgta agctaaaggt
     9901 gcgatttcga ttacgcctcg ttccatcaat cggttcgtat gatccaatcc aaaaatttgg
     9961 tataaagcat cataaacagg ccgcagataa ggatccactt tttcttttag atccccggga
    10021 agaaagccta gattttcacc tgcttccaca gcaggccgcg tcaaaatgat tttttgcact
    10081 tcaccttttt tcaaggcagc gattgctaat actactgcaa gaaaagtttt tcctgtaccg
    10141 gctggtccta cgccaaatac gatatcatgt ttggctaccg attcgacata tttcttttgg
    10201 ccgctgtttt ttacccgtat aggttttcca ttacggtctt tgacgatctc ttcctcatac
    10261 atctcaacaa aataatctaa tgtacctttt tgccccattt tcaatgccgt cacaacatcg
    10321 ggcgtactta cgtggattcc tcgtttgatc aattcctgta atgtccgaat gactgaggca
    10381 gccaaggaaa tctgggattg ctcaccaatg atctgaatga tttctccacg tgtatggatg
    10441 gttgtttccg ttgtttcctc aatcagtttt atatgcttgt cgtgtgcacc taaaagcatg
    10501 ctgacatcat cagcagccgt caatctaatc tctaaagaac tagactcttc cgtcaaaaat
    10561 agacatcccc tttttttcga ttcattcttt cctattttac catactcaga agaaactata
    10621 tagcaaataa gaaaaggttc taaaagagtt gcttaaccat aagtaccaag aaacgttaaa
    10681 aaactagccg cttccattct ctaaaggtct cgtttgaata aaaaaagctg atcatgtaag
    10741 ctatgcataa gatagaggac aagtattccg tctaacttag caagtattct ctgggtattt
    10801 ttcttgtttc aaaaaaagaa aacaaaatat ttgaaatatt cttgcatttc aaaaaaaaca
    10861 ggtgtattat aacgtcaaca aataaatata cagcaaagcg tcgaggaaaa cagtaggcta
    10921 ttcagtgatt tattcccagt gagtcatgta agtgagaaat gacaataaat cgaatagacg
    10981 aacatcattt ccgagtcaat gtcgaaaacg tagatcattg tggctgcctc cattatcagg
    11041 ctagcggata actttatcga aaagcgtccg tgaatgaaga agctttttta agcgaaaaaa
    11101 ggtggtaccg ttctagaatc tagagccctt ttcccaagtg gaaaagggct ttttttatat
    11161 tttaaggtgg tggttttcat ggaatctgat attagtggta tttctagttt ctgcaacgtt
    11221 tattttgtta ctcaaaatga taattattgg aggaaaaatt tatggaagaa acaaaaactt
    11281 attcatggaa gcaattattg atggtcagtt cacttatctt cgggatgttc ttcgggtcag
    11341 gtaatctgat ctttcctgta cacttaggtc aaatggctgg atcaaactgg atcagcgctg
    11401 gtgtaggatt tgccatctca ggcgctcttt tcccattatt agctatctta gctgtagtag
    11461 tgacaaaaag tgatggtctg tatgacttag ctaaacctgt cggaaaatgg tatgctgcct
    11521 tgttcttgat ccttgttcat ttaacgatcg gaccattctt tggtacaccg cggacagcag
    11581 caactgcttt tgaaatggct gctaaaccct ttttgcctga aaaatatgat tcattaggta
    11641 tgtttttatt ctctgctctt ttctttttac ttgcttattt ccttactgta catccaacac
    11701 gtttggtcaa atatgtcgga aagtatttaa actccttgtt tcttgcatta ttagctatca
    11761 tttttgtcgt ttctttattc caacccatgg ggaatctaaa ccaatctgct gcagattctt
    11821 atcagacgaa cgctttgaca aatggcgttt tagaaggata caacacggtt gatgcagtag
    11881 ctttacttgc tttaagtgtc acttttgtcc atgcagttcg tgatcttggt tttaaagata
    11941 aaaaagtcac agaattaaca gcaaaagctg gtagcctgag cgttgcgtta gaagtcatga
    12001 tttattttgg tctggtcctt ctcggtgcga tgagtttgaa taagatgtct ttatcagaaa
    12061 atggcggaac tgcactttct cagatcacta atttttattt aggtaacttc ggtgctagct
    12121 tcttaggggt aatggtcaca ttaggtgtct tcactactgc tatgggactc gttgtttctt
    12181 ttgcacaaga tttccataaa ctgttcccta aagtcagtta tatgacatgg ctgcggttaa
    12241 cgacttttgt ctcttttgtc gttgcgaatg ccggattgga taatatcatc caatggtctt
    12301 taccagtatt gatgcttttg tatccattgt cacttgcgtt aatcttactt tccttaacag
    12361 caaaattctt ccaaaagagt ccatttgtct atcaagtaac gatgttcttt tctgccgttc
    12421 cagccgtatt ggatatgttg gcaaattcgc ctgcattagt gagtcagcaa actgtcgtag
    12481 caagcttact aggattttat catcattatg ttccttttgc tgcattaggt cttggctggg
    12541 tcgtcccaac gttgcttggt tacgctggca gcttgctctt ttattatgta tatcgcgtat
    12601 caggatataa acaagaagca agtgagttac cagaagaata accaaatcaa acacaattta
    12661 acataagaga tattaaacag gaaaaaaaca gctagaagaa agaataagat tctttcttct
    12721 agctgttttt tagttctttt tttacgaaca caaaaaactg cggataatca ctgtccgcag
    12781 tttaaatgat aaaa
//
LOCUS       DAFKHN010000071        12689 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFKHN010000071 DAFKHN010000000
VERSION     DAFKHN010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.071"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            192..761
                     /locus_tag="LY912_002153"
     CDS             192..761
                     /locus_tag="LY912_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBM6955811.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            748..1608
                     /locus_tag="LY912_002154"
     CDS             748..1608
                     /locus_tag="LY912_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBM6955812.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            1798..2502
                     /locus_tag="LY912_002155"
     CDS             1798..2502
                     /locus_tag="LY912_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6955813.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2507..4342
                     /gene="walK"
                     /locus_tag="LY912_002156"
     CDS             2507..4342
                     /gene="walK"
                     /locus_tag="LY912_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBM6955814.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4339..5655
                     /locus_tag="LY912_002157"
     CDS             4339..5655
                     /locus_tag="LY912_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955815.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5656..6525
                     /locus_tag="LY912_002158"
     CDS             5656..6525
                     /locus_tag="LY912_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBM6955816.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6580..7389
                     /locus_tag="LY912_002159"
     CDS             6580..7389
                     /locus_tag="LY912_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBM6955817.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7492..8121)
                     /locus_tag="LY912_002160"
     CDS             complement(7492..8121)
                     /locus_tag="LY912_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBM6955818.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8291..9583
                     /locus_tag="LY912_002161"
     CDS             8291..9583
                     /locus_tag="LY912_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6955819.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9659..10321)
                     /locus_tag="LY912_002162"
     CDS             complement(9659..10321)
                     /locus_tag="LY912_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBM6955820.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10546..10830
                     /gene="groES"
                     /locus_tag="LY912_002163"
     CDS             10546..10830
                     /gene="groES"
                     /locus_tag="LY912_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBM6955821.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            10881..12506
                     /gene="groL"
                     /locus_tag="LY912_002164"
     CDS             10881..12506
                     /gene="groL"
                     /locus_tag="LY912_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBM6955822.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4213 a         2180 c         2760 g         3536 t
ORIGIN      
        1 tttttactcc tttcccgccg tctccccggc gggtctcctg ttcttaacga taaaagacaa
       61 gaaggcttag ccttcttgtt ttttgttttc atggaatccc gctaatcaaa tcacctagtt
      121 aaagcaacta gattgaatgt ttatcataag tctgatatca tgtttatgaa atgaaaaaag
      181 gagcggttat gatggaaaaa atgcgtcagc aattaatgga gtgggggaag gaactagaaa
      241 cattccgtct gcctcactgg gaagaactcc ctgacttaga actttatatg gaccaagtca
      301 gaacgttagt tgatcgttat ctttcacctg tgatacaagg agaaaagcat ccattgctta
      361 cctcttctat ggtaaacaat tacgttaaac taggtttgat accagcacca gttaaaaaaa
      421 gatataacaa agaacacgta gcatttttac ttgcaatcac tacgttgaaa caagtattga
      481 ctattcctga aatcaaagaa gggatattgt tccaaggaaa aacagtagga attcgtgaag
      541 cctataatct attttgcgat gaacaagaag cagctgtgtg gatggtcagc caattagcac
      601 aaggtaaatc tcatccgcaa aaattcgacc aggcaacccc tgtagaatat attgctgtaa
      661 gagcggcaac tttatcgttt gcaatgaaac ttcttgcgga aaaaacgatt gttctagaaa
      721 ccgaatattt aaaagaggag aaaacaaatg aaaaacaata aaatcgcaat tttagtagat
      781 tcaggtacgg atgttccaga agaattgata aaaaaatacg agatgtatat gatcccattg
      841 aaaattattt ataaagatca ggtatataca gataaaattg acattacccc tgaagagatc
      901 tatcaacgtt tgccagagga aatccctggt acatctttgc cggatggtga gtcgatcaca
      961 gaaatctttg agcaaatcaa aaaagacggt tatgaaaagg tacttgcggt aacaatttcc
     1021 agtggattga gcgggacata taatgtggtt cgtttaattg cacaacagca agaagaattg
     1081 gaagcatatg tactagatac gaaaaatatt ggtattggtg caggtttttc tgcgatccaa
     1141 gcagcaaaat ggctggaaga aggagtagaa tgggatcaac tgatcagtaa tctgaatgag
     1201 ttagtcgaaa gaacaaaagt tttctttaat gttgcgacat tggaatatct tcaaaaaggt
     1261 ggacggatcg gtttagttgc ttctattgta ggaaccgctt taaagcttaa cccaatcatc
     1321 tcatgtaatg aagaagggat ttattacaca gtaggaaaag ctaggggacg taaaaaaagt
     1381 ttggataaaa cggttgctta cgtcaaagaa aaaatcggta atgcaaaggt cttcaactta
     1441 gctgttgccc atggggatgc gaaagaagaa gcaattgaaa tggaagcgag acttaaaaga
     1501 gagttcccac aagcaaacca aatctacttt ggccagattt ctccggcatt agtagtccac
     1561 actggtccgg gattattggg tgtcggtgta caagttttag aaggataaat caaaaaaagg
     1621 aaacactgag gtgaaaatca gtgttttcct tttttattga agttagaaca aaaaataata
     1681 aagtattttg cactttcatt ttaattttct cttttgtttt ataggcaaag atgaaacaaa
     1741 agcagaaata cggtataatg agaaggtatg acaataatat ataagaggtg gctctttatg
     1801 aaaaaagttt tagttgtcga tgatgagaag ccgatttcgg atatcgtcaa attcaattta
     1861 gccaaagaag gctatgacgt ttatactgca tatgatgggg aagaagcctt ggaaaaagtt
     1921 gctgaggtag aacctgattt gattttactt gatttgatgc tacctaaaat ggacggctta
     1981 gaagttgctc gtgaggtacg caaaacttat gatatgccga tcattatggt aacagccaaa
     2041 gattctgaaa ttgataaagt cctaggctta gagttaggcg ccgatgatta cgtgaccaag
     2101 ccattttcca accgagaatt agttgcacgt gtcaaagcaa atcttcgtcg cggtgccacg
     2161 gctgcgaagg aaccagaaga ggcagcacct gcggaattga cgattggtga tttgacgatc
     2221 catccagaag cttacatggt gacgaaacga ggagaaacaa tcgagttaac acatcgtgaa
     2281 ttcgaactac tcttttactt ggcgaagcac cttggacaag tgatgacaag agaacattta
     2341 ttacaaacgg tttggggtta tgattatttt ggagatgtac gaacagtgga tgtaactgta
     2401 cgtcgtttgc gtgaaaagat cgaagataat ccaagccatc caaattattt agtgacacgt
     2461 cgtggtgtcg gttactattt gcgtaaccca gaacaggagt aattggatga aaagaaaagt
     2521 ccgctttttt cgatcagtca attttaagat cgctattacc tttattctga ttttattgat
     2581 ctcgatcgaa attattggtg cctactttat acgtggttta gaacgttcca cgatcaatac
     2641 atttattaaa gatatgaatc aaacggtgga atcattagca acaacaatca gcccggaatt
     2701 gaatcgaaaa gataatgcag atgatgaaga ggtaaatgcg aatatcaaaa gatttattga
     2761 aaacagtgcg actagcgata tcatcgaaat acgggtcgtt gacgaaaaag ggatcatccg
     2821 aggaacaacc gatgtcaatg aacaaagcgc tgtgggaaag aaaaatgatt atgttgatat
     2881 caatgatttc acgactaaac gttatgttgc tttagataac gacgataaac gggtgaatat
     2941 caatgttcaa ccgatcctgt ccccgaccgg cgatgccgtt atcggggctc tttacgtcaa
     3001 aagtaatatc gaacaaaaat attcggaaat caataacaca gcagtcattt tctttactgc
     3061 ctcactaatt gcggcattta tttcaatgat cgtatctgtt ttagttgctc gttcgattac
     3121 acagccgatc ggtgaaatga gagaacaagc cattcgaatc gctagaggag actacagtcg
     3181 gaaagtcaaa gtgcatggac aagatgaact tggacagctg gctgatacct tcaatcagtt
     3241 agctgaacgt attgaagaag ctcaagatac aatggaagct gaacgcaatc gtttggatag
     3301 cgtgctatcc catatgacag acggcgtcat tgcgacagat cgcaggggta aagtcattac
     3361 gatcaatgat atggctgttt ccttgctaga tatcaaaaac gaggaagcaa tcggacaatc
     3421 gattttgaca cttttagata tcgaagaaga atatacgttg cggaaattat tagaagatcc
     3481 aaacgaaatg gtacttgacc gttcaaccag tacattggaa agtgatcaga tgatcttgcg
     3541 agtagacttt tctatgatcc gtcgcgaatc aggttttatc agcggattag tagctgtctt
     3601 gcatgatgtg acagaacaag aaaaaacaga acgggaacgt cgtgaattcg tctctaatgt
     3661 ttcccatgaa cttcgtacac cgttgacaag tatgcgtagt tatatcgaag cattgagcga
     3721 aggtgcgtgg aaagacgagg aagtagcacc aaattttttg aaggtaacgc tagatgaaac
     3781 agaccgaatg attcgaatga tcaatgacct cttaaatcta tctcgcatgg atacaggtaa
     3841 tacccagctt caattagaat atgtcaattt caacgagtta gtgaattttg ttcttgaccg
     3901 gtttgatatg atggtgggaa atcaggaaaa aaattataag atccgtcgtg aatttacgca
     3961 aagagatctt tgggtcgaag tagatacaga taaaatcatc caagtagtcg ataatatcat
     4021 gaataacgcg atcaagtatt caccagatgg gggaacgatt acttgtcgct tattagaaac
     4081 gcataataac gtgattttaa gtatcaccga tcaaggattg gggattccta aaaaagatct
     4141 gaaccgagtg ttcgagcggt tctatcgagt agataaagca cgtgcaagag cacaaggtgg
     4201 gacaggactt ggattagcta tttctagaga agtgattaag gcgcatcgag gcgctatttg
     4261 ggcagagagc aaggaaggaa aagggtcgac tttttatatc tcgctgccat atgaacctta
     4321 tgaggaggaa tggtgggaat gagaatctct gaaaaagtcg ttcgtatagg actcattttg
     4381 atggttgcgt taagcatata cttctcttat gcaatctggc tgagcccagc aggaaaaagt
     4441 tcaatcaacg tagatgagac aaacactcaa atgatcgagt ctcaaagcaa tcgaaaaact
     4501 tccgaagtct ttcttccgct tcatgttaca tggcaccatt cgggaatgat ccaagaaacc
     4561 aacagtgaaa atctcgtgta ccgattgcaa ttgatcatcg ataaagcaag atttggaaag
     4621 ctttctgaag tagtttcagg agacaaatca cagtttgaac aggtgaaaaa tctgaactct
     4681 ggttttgagt tggcctataa tgcgcctttt ttgctaagag aatacaagga agcatttgat
     4741 ttagatttag atgtgtcgaa cttggcaaaa gaaagcgaaa atatgtattt tactagaata
     4801 caattcgatc aaggaaataa aaaaatccga tttttgaatt attcgaacca tctcgtatat
     4861 gaagcaaata tttcgttgaa ttggacagat atcaataaag aattaacagc aaaagacaca
     4921 aaatggacag aaatgacaac agaaccatcg acgatcgaca cgcaatatgc tacgaaacat
     4981 tcgatcaaac tgaagaagta tagttatatc ctgtcacagc aaccctatac actttttaga
     5041 aatgcttttt tccagaaacc agatagcgtg aaaaataatg atgaaagcaa tgaattgatt
     5101 ttttacggtg ggaatgaaac aatgtctatc cattcggaaa cgcaagtagt tgattttcgt
     5161 ggagagctgc cagagaaaaa agaaaatgct agtgtatttt ctgaaagttt cccctatatt
     5221 agcaaattag gcagttcttt agggaacctc agatattttg accgcagtga caatacgatc
     5281 gattatcgga tattcgtgga aggcttcccg gtttttggga cagacagcag aggacagatt
     5341 ggtgtggaag ttggcggtga aacgaatggt tctgtgcaag tgaatatcca aaccagtttg
     5401 aatacgattc aagtgccgat accttcagac gaagaagtag aacttgcaag tacgaatgaa
     5461 atcatccagc agttaaaagc taagggagca gatagcaaca agattggttc agtgatcgtt
     5521 ggctatacat ggcaaaatgt caaagaaacg aatcgtgtcg ttgatctctt acctgaatgg
     5581 tatgtgaaat ataaagataa ctggtattca gctaacgacc ttctggaaaa attacctgga
     5641 ttggaggcga attaattgga tttcaaaaaa atcgaatgga tatttttcgt cgctttttta
     5701 gggttgaatg tgtttttatt cagcagttat catgacgcgg tataccaaga aaacaatgtc
     5761 attcgctcta atcagactga atcaatccaa caacgtctgg ctagcgacga tatcacttac
     5821 acggggaaga tttcgtctga gaacaagcaa ggctattatc ttagcgcgga gcagaccaat
     5881 cttagcactt cattagcgaa ttatcgcaag gctggtaaaa gcggcttgct ggcaagtggt
     5941 gtgtttttag acggtgatgt tttgacgaaa tctttatcca gttcagatgc tgaaaagaac
     6001 gtgatcgatc cagataaaat tagtagttcc ttggaagatt ttttatctaa caaagacaat
     6061 attttattcg gtaatgatta tgtgtacacg aaaaactttt ctcatttaga agaagaacca
     6121 ctagaaatcc aagcaagcca agagtatgaa ggcatcccat tcaatgatga tacagcaaaa
     6181 atcgttcttt ctttagaaaa aaacgataat gattatagca tcacgaaata catgcagacg
     6241 catttatctg atatcgagca gctgcgcgaa aagacggaac tgtatacgga agaggaagca
     6301 atcaatacat tgtacatcaa taacaaaata ccaagaggat caaaaatttt atggcgtcag
     6361 ctagcttatt cctgtattct gaaagtccgg gaaaaaaatg tgtatgttcc tgtttggcat
     6421 gtagcgatcg aaacaagcga taaagtggtc caaattgaga gcgtcaacgc tttcagcaat
     6481 acgatcgtga caaacaatac tgtaccaaaa gtggaagatc aataaaaaag cgagtataat
     6541 gaaaaaagtt tacaaagtaa gaagggaagt aggagtcaaa tggctgaaga aaaaccagct
     6601 tttaaaatca gtatcctagc aagtggaagt tcgggtaatt cactttatat cgaaagtgaa
     6661 aaaaaacggc ttttggtcga tgcaggactt agcggtaaaa aaatcacttc cttgatggct
     6721 caaattgatc ggacaccgga ccaattagat ggaatacttg tgacgcatga acatcgagat
     6781 catatacatg gcgtgggtgt cttggctcgt aagtatcatt tggatgtttt tgccaatcag
     6841 cagacttggg aagcgatgga accactgatt ggaaatgtac cagtggaaca aaaacatcta
     6901 tttgagatgg ggaaagtcag aacattcggc gatatcgata ttgagagttt cggcgtctcc
     6961 catgacgcag cggctccgca attttatcgt ttccataaag aaaatcggtc attcgtcatg
     7021 ttgacggaca ccggatattg cagtgattat atgcgaggtg tcattgaaaa tgccgatggt
     7081 tatttgatgg aaagtaatca tgatcttgag atgttacgca tgggacctta tccgtggaat
     7141 ttaaaacagc gtattttagg agatagagga catctttcca acgaagacgg tgcacttgtc
     7201 atgactgatg tgatcggtaa tcggaccaaa cgaatctatc ttggccatct tagcaaggaa
     7261 aacaatatga aagaacttgc tcatttaaca atggaaaatg ttttgaaaga aaaagatttt
     7321 ggcgttggac atgattttga aatctatgat acagatccag atgaagcaac tgagctattt
     7381 tcgatttaaa cagttcaatc aataaaaata taaaaagcag aagataaaat caatcagggt
     7441 tggttttatc ttctattttt atttttttag catattaaaa aaataaccgt attatcgact
     7501 gactacactg atgtgctgct tttcatgttt ctcatccagt atctcatcta ctaatgcaat
     7561 cgcgtaatct gccatgctga tcgtactgtc gctagcagcg tttctttgta aataatcatc
     7621 acttaacaaa taagtacctg tacgtttgcc atgtggatca aataaagaag ctggactgat
     7681 ataagtccaa tgtagatttt tagattgttt caattttaac aatccttcgt acatattgaa
     7741 agctgttgga tagaagggtg catttttagg tacttggtca atcatacgag tcgtcttttc
     7801 tgtatctaag aataacgaag aggcaccccc aacgacaatt aagcgtgtat cggttccttc
     7861 aagcatctca atcaaatggg acaaagaagt ttgatgcatt tcttcttttc ctttgggagc
     7921 gttgaaagca tcaacgacaa catcaaaaga tgcaagatca gtagttgtca actcaaataa
     7981 atccttttgt ataaacggaa catctgatgg caatttttct ggatgacgca cgattgccgt
     8041 cacgtctaaa tctctggaca atgcttcgtc taaaataaat gaacctgcat ggccagtagc
     8101 tccaatgagt gcaattttca taaaaaacct ccttttttat tcctgtccat tgtaagcagt
     8161 tgctgaatat tcgtcaaaga atccgatttt tgaaaagctc agtgcgcatt cctttcatgg
     8221 ttcgtgatca ttgggtatag ttaaattaag aaaactgatt gataaaaata gaagttgaag
     8281 gagataagaa atgaaagagt ggttagatcg tgccttttta ccaatgataa catctgttgt
     8341 gaatcttaga cccttaactg ctttgcgtaa tggaatgact tacacgatcc caataattat
     8401 tgttggctcg ctgtttttct tatttgctca ttttcctgtg gattacatcg ctcagtggat
     8461 agacaaaaca ggattttcta tgtattttac acaagtatac caggctacat ttgatgtgat
     8521 agccttttgg atcgtttttg ccattgcata cgcttatgca aaagaagaag acatcgatcg
     8581 cttaccagtc ggcataacag ccttgtctgc ttatctactg cttattcagc cactaaatac
     8641 tcagatagat actgtctgga caggtgctga agggatacta ggagcagtta caactgggct
     8701 catcatcgga tggggctatg cacgtttagt aagacttgcg aaagggtgga agcaaagaga
     8761 gaagatacct gaaaatgttt ggcagtcttt tacttcattg attccaatca ttgttatagt
     8821 cacttttacg cttatcggtt cagcggtttt tcaacatttg ttcagaatga ctgttgttca
     8881 aggagtatgg acatatgtcc agcttcccat tcaatcgttc atagacacgt tgtttggtgt
     8941 gcttttatta ggtttttttg ttccgttttt atggttattt ggtcttcatg gatctgcgat
     9001 ggtcaatggg ttggttagtc ccgtcttgca agcgaattca ttagcaaatg cagaaatctt
     9061 agcctcagga caagagttga cggtggcaaa tggcggacat atcgttactc agcaatttct
     9121 cgatcagttc atgacggtta cgggtgctgg attgacgtta ggggctgtat tttttatgac
     9181 ggtttttgcg aaatcgaaga aatacagaga attaggaaat cttgctcttt taccagcctt
     9241 tttcaacatc aatgaatcaa ttattttttc cacaccgatc gtgatgaacc cgatgatggc
     9301 tgttcctttt attttcgcac cggtcgtttc aggattgatt acctattccg ctttatattt
     9361 tggattcgtt cctttattta cagcagtcca agtcccttgg acaacaccgc cgatcctctc
     9421 gggtttctta gtaggcggag tgcctgcagc gattttacaa ggtatcgtgt tgtcaattag
     9481 ttttttcatt tatttcccat ttttgaaaaa aatagattct gcaaactgca aaaaggaaag
     9541 acagacaaaa aatgatggag cagcagaaaa gatgaacgac taaaaaacaa aaatactcct
     9601 gtcgctttag attgggaaaa tcaccaatct aggatgacag gagtatttat agtcatgttt
     9661 atactagccc tttttggaca gctaattgaa caagaacaac taatgtgttc attcctacgt
     9721 gtgtgatcat cgatgtccag atccgaccag ttgctttgta ctctaggctg aagaagaaac
     9781 ctaggaaaaa gtagattagc agatgaccat cattatgagc aaacgcaaac agcaaagagc
     9841 tgatcactgc tccgacccaa aaatttgaat atcgactgat gatccccagt atactgcggc
     9901 ggaatacgaa ctcttccatg atgggtccag caacagttgt cgccaaaata aaagcgggtg
     9961 cttccatgat catctggatg atattttgtg tattctcgga aggggttgct ttgccaaaca
    10021 atacagattc taacatgaca gcgatgcttt gcagaatcaa tgcgacaaag attccaacca
    10081 atccataaat aacaatcttt ggagcagaag ctttttttac cgctgattcg atcgctaagg
    10141 gttcacgttg cttaaaataa aaaatagcta ggacaacggc gcctagtata tacatgactg
    10201 cagttgctgt gatcaattca gacgtagatt ttacaagtcc tatcgaagct aggatcaagg
    10261 gtgagataaa aattagacca tagcaaaaaa tgctgaggaa gctatatttt tttaaagaca
    10321 tgtaattcct ccttttaagg gataacaagc atgcaaggca agcttatatc gattgatttc
    10381 aattatatca taatttcaat aagcagctgt cagaataaaa tttcttttct ttgatttaaa
    10441 agcttgcaaa aaagagggag aatgagtatt attaaaaatg taggttagca ctcgaaggtt
    10501 aagagtgcta acagattaaa aaaagagtta tcggagggat ttatcgtgtt aaaaccatta
    10561 ggtgatcgcg tcattatcga agtcgcaaaa gaagaagaaa aaactgtcgg aggaatcgtt
    10621 ttagcttctg ctgctaaaga gaaaccccaa actgggacag ttgttgcagt cggtgaaggc
    10681 cgtttgttag aaaacggtga aaaagttcct gccgctgtaa aagcaggcga ccaagttatg
    10741 ttcgaaaaat acgccggtac agaagtaaaa tacgaaggaa aagaatatct gatcgtcgca
    10801 ggaaaagata tcatggcgat tgttgagtaa atttggaaga taaaaaaata atcaaaaata
    10861 atcaatgagg tgaatcaatc atggcaaaag aattgaaatt tgcagaagac gcacgcgcag
    10921 ctatgttacg cggggtagat aaattagcag atacagtgaa agtaacatta ggacctaaag
    10981 gccgaaatgt cgtactagaa aaatcttacg gctctccatt gatcacaaat gatggtgtga
    11041 cgatcgcaaa agaaatcgaa ttagaagatc attttgaaaa catgggtgca aaacttgtat
    11101 cagaagtagc atcaaaaaca aatgatattg caggagacgg tacaacgaca gcaactgttc
    11161 tgacacaagc aatcgttcgc gaaggtttaa aaaacgtaac tgcaggtgct aatcctctag
    11221 gcattcgtcg cgggatcgaa ttggcaacaa aagcagcagt cgaagaattg cataatatct
    11281 caactgttgt tgattcaaaa gaagccattg cacaagtagc agctgtttct tcgggttctg
    11341 ataaagttgg acatttgatt gctgatgcaa tggaaaaagt tggaaacgac ggtgtcatca
    11401 caatcgaaga atcaaaaggg atcgaaacag aactagatgt tgtagaaggt atgcagtttg
    11461 atcgtggtta cttatcacaa tatatggtaa cagataacga caaaatggaa gctgttctag
    11521 aaaacccata tatcttgatc acagacaaaa aaatctctaa catccaagat attctgccat
    11581 tgttagaaca aatcttgcaa caatcacgtc cattgttgat tattgctgac gatgtagatg
    11641 gtgaagcatt gccaactctt gtattgaaca aaatccgtgg aacattcaac gtagtagctg
    11701 taaaagctcc tggtttcggc gatcgtcgta aagcaatgct tgaagatatc gctattttga
    11761 caggtggtac agtaattact gacgatctag gtttagaatt gaaagatgca acaatcgaaa
    11821 acttaggaaa tgcttctaaa gttgttgtag ataaagacaa tacaacgatc gtagaaggtt
    11881 ctggagaaaa agaagcaatc gaagctcgtg tgcaattgat caaaaaccaa attgctgaaa
    11941 caacttctga ttttgaccgc gaaaaattac aagaacgctt agctaaatta gcaggtggtg
    12001 tagctgttgt taaagttggt gcagctactg aaacagaatt gaaagaatta aaattacgca
    12061 ttgaagatgc attgaatgct acacgtgccg cagtagaaga aggaatggtc tcaggtggtg
    12121 gtacagctct agtgaacgtt atcagcaaag tttctgctgt agaagcagaa ggagacgtgg
    12181 caacaggtat caagatcgtt gttcgtgctt tagaagaacc aattcgtcaa atcgctgaaa
    12241 acgctggtta tgaaggatca gtgattgttg ataaattgaa gaacgtggaa ctaggcactg
    12301 gtttcaatgc tgctactgga gaatgggtaa acatggttga agcaggtatc gtagacccaa
    12361 ctaaagtaac acgttctgcc ttgcaaaatg ccgcttccgt ttctgccttg ttattaacga
    12421 cagaagcagt cgttgcagat aaaccagaac cagcagcgcc agcagctcct gcaatggatc
    12481 catcaatgat gggcggtatg atgtaagaaa aagcaacttg cttatctaca actgatcatt
    12541 agtgaaagac agataaaaag aggctggaac agaagcgttt aactccaaga aataagaaga
    12601 aattcacgga aattgctttt caaatttttg tgaatttcag cttatttccg aaggagttgc
    12661 ttctgcttcc gctgtttata cgtgtttag
//
LOCUS       DAFKHN010000072        12438 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFKHN010000072 DAFKHN010000000
VERSION     DAFKHN010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.072"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(52..450)
                     /locus_tag="LY912_002165"
     CDS             complement(52..450)
                     /locus_tag="LY912_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBM6955823.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(642..1409)
                     /locus_tag="LY912_002166"
     CDS             complement(642..1409)
                     /locus_tag="LY912_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBM6955824.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            complement(1444..2667)
                     /locus_tag="LY912_002167"
     CDS             complement(1444..2667)
                     /locus_tag="LY912_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HBM6955825.1"
                     /translation="MESYQFQIFKLVPSLERRGNRMKITEKNVNPKFEPTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            3647..4450
                     /locus_tag="LY912_002168"
     CDS             3647..4450
                     /locus_tag="LY912_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBM6955826.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            5035..5490
                     /locus_tag="LY912_002169"
     CDS             5035..5490
                     /locus_tag="LY912_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955827.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            5609..6667
                     /locus_tag="LY912_002170"
     CDS             5609..6667
                     /locus_tag="LY912_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HBM6955828.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            6709..8658
                     /locus_tag="LY912_002171"
     CDS             6709..8658
                     /locus_tag="LY912_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBM6955829.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            8661..12302
                     /locus_tag="LY912_002172"
     CDS             8661..12302
                     /locus_tag="LY912_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955830.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDRKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
BASE COUNT         4348 a         1860 c         2349 g         3881 t
ORIGIN      
        1 catacgtcct aaaacaagct gtttttgctt aatatgatca tctgagagac atcaaatcaa
       61 cttttctctc aacaaatcat tcaaagcttt cgacagatta atattctctt cagccgctaa
      121 aacatttaaa tagtgttcca cagtcactga ttttcgatca taattttgct tgtttcgagc
      181 tttagcaact ttcgtattag cttttacgac aaataaatta acattctcag atcgcttgat
      241 tcttgcattt aactcttgaa caggcgtagg cgatggaatt tctttttctt gcaactctaa
      301 aagcaccaag tatccttcca atacttcttg cgccatctca aaagcatctt ctaaagtttc
      361 accatgtgta tataagtctg gaaaatctgg gaatttaact gcatattcat ttcctttcca
      421 ttcgaatact gcacaaaaaa agtatttcat cgcattgcac ctctctaatt aaaaaataat
      481 ttttgctttt ttgtttcaaa aaaaagaatc gcctaccaaa aaaattgata ggcgatcaca
      541 agctaattaa cctctaaagg agattaatac cttgctccca aggcactata tatcttagca
      601 tacgtctgaa gcatcttcaa acgagtaaga tatattttgc attaacctaa ttttttttct
      661 ctataagttt tttcatcaaa ctcactagaa atattaaact ggacagcaaa attgtaattt
      721 ctgccttttc taactttagc aaaatcaata ttcagcattg atttttcatt aatttcctca
      781 actgattccc ttaaaacacg tctatcaaaa ttcgatattg ttttatactc attttctgtt
      841 ttcgtaatct cacgaatttt aactatttca atcaggggat tcttatatat ttcagctttc
      901 tcaaaatctc ctttattttt ggcgataaga tattttttat aatacatcgc caaatatttg
      961 tataacacga tgctatattt tttttgaaaa gatgctaagt cttcaaaaac aaagaacgga
     1021 tacttctttt tgattgagac aattaaggga attacatctt ctgaaaaact gaaagataca
     1081 ctatgctctt ctaaatccca atgaatccga tcaatagcag atacagtagt atacgtctta
     1141 tattttttgt ctagattcga aatttcataa actgcttgtc tttgcaaagt gttaactatg
     1201 gtttttagtt ccgtttcaag attttgatca acatccatgt aattaataat cgctttaaca
     1261 ggtaaatcta ctacgcctgt tttctttagc tttgtgggtg agatataact gaacagcaat
     1321 tgataaagtt catacgactt taaatccatt ttcatgtcaa ttgttgctaa gaactcctca
     1381 ttgtactttg tcagttcatc ttttttcaaa agtttttcct tccttcacgc attttttcag
     1441 ttgttaatca taaaggttca cataaggcaa ataactcgta attgattttt cgagatattt
     1501 aacagtattt tttattgtgt aatcctcctt atgagtagca acgtaagata ggtgattgac
     1561 aactgattca aatcctctat ctttggataa acgatcataa agcggataaa ctttattctg
     1621 aagtcggctc ataagtttaa gatcgcataa gtcggcagaa ctgatcaaaa agtttttgat
     1681 tagtaattta gtgtatttgc tattcatagc tttcaagtac gattgattca ttttctctgt
     1741 tttatcttct gcgcctttta aataagcagg gtctctttgt tcttgcttat aaggtaccgg
     1801 aactgacatg gtacgtgtaa gcaagaactt tatgtttgta taagtatgac ccttcttgat
     1861 aagctcatag tcaattttaa aatcagtgta tttattcagt tgggcaatcg gttctttaat
     1921 tacacgtctt tcaaagtctc gaaaagcttt atattttttc tcaatactaa atttctttcg
     1981 taaatctgca atggagaaaa caggattttt taatctatca agtgattttg tactccatgt
     2041 taagttatct ctatttgctt catacagatt aaaatcttta gtgaataatt gaaaaaaact
     2101 gatcgcatac ttgcttgtca agttaactac ttgatcaaat gtatattgcg taaaatgatc
     2161 ttctaagttc gttaataaag gcataattga actactaaat ttaatagata ctgcatcaga
     2221 aaaatcattg aattcagtaa tttctagcgg tgagatgact ttgtattcag tcttaccgtt
     2281 aggtttagtt ctttgaattt taatgacaga ttgctgatgc aatttttcaa taacttgttt
     2341 taatcttgaa tgttttgaag aagatgaact agaagacatc aacgcaaata aagccttttt
     2401 agatacttta acagtattat taaaaggcgg atttttaggg tcaagatgtc ctatagcata
     2461 aagataaatt ttttgtggca tagcatccat ttcaacaatg ctatctacaa gttgattcga
     2521 taaagtaaca gttaaatcaa acttttttag attgctttcg gtaggttcaa atttcgggtt
     2581 tacattcttt tctgttattt tcatacgatt gcctcttctt tctaagcttg gtacgagctt
     2641 aaaaatttgg aactggtacg attccattga ataagtatag acctgttttc gatacgatac
     2701 aataagaaat gtatcgtaaa tttataacat aactcaatct ctgtaaaaca cattttattt
     2761 ttttaatcaa ttttcattga taagacagca gaaatcgcta ttttagaaca ttttcaatat
     2821 aaaaatcctt ttcaaaaaaa tacgaaatta taaaaattac caaaattaaa aaacaaatat
     2881 ttttctagtt tttagaaata aattcacata ctttttcttt ttttggatat attcggaata
     2941 ccacatcgct ttttgtccac gtttgcatcg ctttttgtcc acattcacat cgctttttgt
     3001 ccatgttcgc atcgctttat gtccacccta aaatctattt aagattgata taaagccttt
     3061 ttgaaggttg ctaaagtttt aaagattaaa atatatatta taaatataaa taaaagggga
     3121 agctgaagct tcctcctttt cctttttttc aattattcaa agttacacaa gcaaaataaa
     3181 ctcctagata gtgttagttt tttttaagat tttttatttt taagattttg aaataagaga
     3241 ggagtaatcc tcctttatta aatatctgtt aatatatctg ttaaatatct gttaatatat
     3301 ctgttagggg aggcttaatc tcttgggaga gtaagtatta aaggggtata aaggtaacac
     3361 ttttggacag taaaggtaac aaaagtggac agtaagggta acagttttgg acagcaaagg
     3421 taacaaaagt ggacatttga ggtatcacac taggataaga cgttaccttc ggttttcttg
     3481 atttggaagg cgaaaaaata gaaaattaga ttagtaacaa atctttgttg actgttacct
     3541 ttagttgtga tttaatttag gtaacaagca gaaaaaattg tttcctttaa ttagtaccag
     3601 attaacatga ttaaaggagc gcaaaaagaa gattggagag taatcaatgt ctcaagaagt
     3661 taccgaaaag attattgata gtgatgtaga tttagtatca gaacaaacaa atgcaattgt
     3721 gcgttataac aatggtctga atacaacagc tttgcgagga tttaagcctg ttgaaatgga
     3781 tgtgttttgg gctattttat caaaaatgaa acgtcaagga acagcagaag taacttttga
     3841 tttcaacctc tttcgttatt tggtcaaata cgacagaaga gaaaaggaca gtttttattc
     3901 tgtgttaaaa gatttgagtg acaaactagg taatttaacc taccgttttg aagattcaga
     3961 cgtctatgaa cagctgtggc tttttcaaaa attccggata gataaacaga aggaaacagt
     4021 tacaattaag gcaaatgagg aatttgaatt tatcttaaac tcaattggca aaaactttac
     4081 tcgttttgaa cttgataatt ttacaaaact aagaagtagc tacacaaaag aattgtatcg
     4141 tcatctcatg caatacagaa ataaagagtg gcgaaatggt tattgggtag tcaaagttga
     4201 agattttaga agagcattaa gtataccttc aagttataga atgacaaata ttgataaaag
     4261 aatactagag caggcgaaag aagaattttt agctcctgat gaaaacggaa tacaggtatt
     4321 tgaaactttt gattatgaaa aaatctatgc aaagaaagga agaagagttg atcggctcag
     4381 attcactttt agtgagccag aatcaaactt gccaaccatt tcaatgcata attggttaga
     4441 agaagattga gaagaagcag gttgtaattt taatacaacc tgcttcttta aaaaagtatg
     4501 ggtaacactt ttggacaata aatgcaagaa gtttttttgt aagcaagttt cagtctaaat
     4561 aatatttgaa agaatggcta atctatacaa attttaacaa ctatgggtaa cacttttgga
     4621 caagtcaaga aaaaaaacaa tttttcttaa tttgttgatc gactaaaggt aacacttttg
     4681 gacaacacag aataaaaagt ccggtgatat cagttttggt aggaaacatc ttaatatctt
     4741 tgtgagattg aaggtaacat ttttggacaa gtcaactatt tgttaaaagt taatatagag
     4801 taattagata agttttttct tttcgtctga taaatggata atattagtta ttttattgct
     4861 aattagtctt tcatgatgac tgaaatagct aaaataaata tctcgttgga taattgctga
     4921 tactttaagg gatatctaaa tttgctgatt gatttattta tgttattatg atattataat
     4981 aacataaatg tgttacgccc gaacctcatt ttaaaaaaat gaaggggtga gacaatgaat
     5041 gctattaatt ggcatgaatt tgttaactat atggagagct tactagatga tctaaaaagt
     5101 tttagtattg ctgatgcagt aaagcatggg ttaccagtta gtacaacgat gaaattacga
     5161 ggattgaaaa ttccagatga aattattaag ctgagaacta aaacaattat tgaaaccgca
     5221 aaagtcgttg acaatatgaa ccatgaacta aaaggcaaga aaacaactta cgagaaagat
     5281 tttgaacgtt ttttaaaatc tgttattgga aaatatctag gtaaaaaatc tttcagtgaa
     5341 ttgagagatg aagagattgt acctactcca atggttagca aaatccgaaa aaacaaagcc
     5401 gaggggaatt actatcttgg tacaatagca aaaatcattg attatttgga aaataaagag
     5461 caaaagaaag gaacgaagaa aggaagataa tttttgtgtt aaatattaat ggggaagaat
     5521 ataccgaaat gattcaaaat cccgaaccta gaattaccga aaaaacgtct gattgtttgc
     5581 tcttttatga aagggggcag acaaactaat ggaaaaaaac gtcaattcaa catctaccaa
     5641 agatcaatac agtattattg gagggttgct tggtgataag gataagagaa cacgtcacgg
     5701 attacgcatt atgcttgcaa cttttctagg agtgcttttt ttattaacag gcttgggtag
     5761 ctacatttat caattaggaa actataatta ttatctcgtg aacaatacaa cacctatagg
     5821 ctcttcattg gagtttgctc gatcaggagc agagatcact atttcagatg tgtggacaga
     5881 tcaaaacaga gatgtaacag tagtaaaact cggttactcg caaaacgcta gaaagttgtt
     5941 atctacgcaa ggaaaaaact acaacttata tatggcaacg aaagaaaaag atcgtcctaa
     6001 aaagcttgaa atgagctatg ggatgttaag tactgatggg gatgctttct tattcctaaa
     6061 aggtaaatta gatgaaagag cttatcaagt ttttattgca aaccaagtat cactaatttc
     6121 tggtgatgat acagctgacg atgataccaa agtcaatgtg aatgaagcag attcagttac
     6181 aaaagcactt tctcaatatt ctatgaatga tgttaataat gaaggagtaa tttcttttgg
     6241 gaaaaaagca aaacctgtta atactcctga taatatcaat ttcagaataa atccatattc
     6301 agattcaact aatgtctatc aaggaagctt tcttaccaaa gatggcgata ttgattattc
     6361 aaaagttgta gcagttacaa gtaagaataa tgttgtaagt aagttagaag atcagttaaa
     6421 tgcttcaaat actaacatca agaaaattga agctacaaaa gctgagtatc tggaacgttt
     6481 acaacaaaat cctgacgata aagattcgca agaaagtatt cgtcaactag acagtcgaat
     6541 ggagaccgaa attaaagcaa tcaatgatac acaaaaattg attgatcaat acaaaaatgc
     6601 tgactttaac aaagattctt ttggagacat gaagacgaca tttaagtacc taactctgac
     6661 tgactagaag taaattattc ttattttaga ggaagtgaac acaaacagat ggaaaatagt
     6721 accgagtttt ttaagaatat tcaaactgaa tttaatcatg ctctcacacc aatgaaacca
     6781 ccgaaacata agttagtggg acgtgatgac gaactccatg agttgtcact gatcttgaat
     6841 agaccggaaa caccgcaagc tatcttgtta ggtgaagccg gaacaggtaa aacagcactt
     6901 gcaagtgaat gggctgaaag acagcgacaa gatggaaaga aagtacaagt atacaaatta
     6961 tcaatcggac aattgcgtgt tgggggagat gatgtcctcc aaacacgttt agaaacatta
     7021 attccaagat tgaaagaata tgagcgaatt ttaaaatctg aggacaaaga aaatgaattt
     7081 gtcctcttca ttgacgagtt tcataaagtt gttagctctt ttggtagtgg caataaaatt
     7141 gggggtgatt cgctaaaaga accgttagca aatgaatcac ttcaattgat taccgctact
     7201 acaagaaaag aatatgaaaa ctatatcaaa agagatgatg ccttagggag acggttacaa
     7261 ccgttagaat tgaatgaact aaaaagcgat gttgtcgtcg atattttgag acaatggcta
     7321 aatacatcct ctgttaaaga tgatcctcag gcttctttta aattatcgca aaggattcct
     7381 gatgaattac ttcaagaaat cgtacaagca aacaagcttt atcgtgagga tttgtccgaa
     7441 ccggctaaat caattgccgt aatggaggat ttgattgcaa aagatcgagt agacggaaat
     7501 gcttataatc gagaaagtct attgcaaata tttggtaagt ataatattca gctagattct
     7561 gattttgata tggaaaaact tcaagaggaa ttaaagtcca taaaagggca accgttagca
     7621 gtttatacta taacaatgtt gtttaaacgt atgaagcttg gatttgatcg ttttaaaggt
     7681 cgaaagcaac caaaagcaac tgctctgttt acaggatcaa caggggtcgg taaaactgca
     7741 atggctaaag ccgtggcaag aggactttat ggcgatgaaa ataaagttct cttagttaat
     7801 atgccggact acaaaacaaa agatgatgca atgcgtttta gacgactcat aggtactcat
     7861 gtaaggcatg atccttctgc gattattgtg tgtgatgaat atgagaaagc tggtgtagaa
     7921 acactcgatg cctttttatc aattttagat gaaggtagga taagttttac tgaaagagga
     7981 tgggatgatc gagaagttca cgacactgtt tcattgtcaa atacaatttt atttgcgaca
     8041 acaaatgcag gtgcggagat gttcgattcg ttaaacagat atagctcact atctcgtgtt
     8101 acaaacaagg aaaattctaa tgaatatagc actgaactaa aaagagaata ccgaaaagtc
     8161 gcatcaggga tcaaacaagc cttgattggt gaaggtctaa agcctgaagt tattaaccga
     8221 tttggacgaa tagttccatt ttgggcttta tccgaacaaa ctcttctgga aattgcttat
     8281 aatgaaatgt tgaagagtgc tgaattagta cgaaaacatt taaatataga tttacgtctt
     8341 ccacctagga aagaaagagt atatggtcaa aatttttatg cagacgatct ctccatgcac
     8401 ttagtttttg acatggcttc acaagaggat tctaaatcag ggggtgcaag gaatatcttg
     8461 catttagttg aatctgagtt tgaagaagcg attactgaag caataattac ttatccaaac
     8521 gcaaaaatat tcgatgttaa gttgagtgaa gccggagcgt ttgaaggaaa aggtgattct
     8581 aatgctgaaa ttattgcaaa gccttccgtt gctgaaagta aagaaaacaa gattgtattt
     8641 tcgattggag gggcgtagct atgaaattca agaaatattt actacaaaac cttagaataa
     8701 aacgatgggt cgtaagaggt ctagttattg gaggagtatt agcagttact ttaggcgctc
     8761 cttttggaat gaatgatcca actcctgaca atcaagatag caaacaagaa acagttataa
     8821 ataagaacgt tgcatatgcg gaaagtaaac cggcagaaca aggaatgtgg acactatatg
     8881 ctcgtatcct aatgggagat aaagaagtta atgatagtgc cgctaaaact ggacaaatga
     8941 atttgttagg acaaggtggt atcagtgccg atttccctta ttctgacatt tctaaacaag
     9001 gtaattcgat tgcagggggt aatgcaggta ctcaactagc atctacttta gcaacttata
     9061 gttactacgg atatattgaa acagtctcag gaaatgctat tgccagtcaa gcatcatcca
     9121 ttctaggaag tattggtagg acgattggta gttttatcgg atcaattagt ttaatccttt
     9181 ctaatattgc tgaatccata aatgaactcc ttggaaaatt tttcatgagt atgaatatat
     9241 tttctcttat ggggtgggga gaaggtggat cggatgtatc taatccggta tctaaagcat
     9301 taactagctt gcttaacaat ttgggattaa ataatgaatt atttaaagcg atagcaagct
     9361 tatctatgct ctttttcaca gcaatactag gttatcaagg aatgaaatta ttgtcgaaag
     9421 atggtgttaa ctcgaaggga ttatcaccag tacttgaaaa atggattgtt cgtatttttg
     9481 tattgtttat attcttacca gtggcaggat cgctattggg agtttatatc aacggcatcc
     9541 agtcagcaaa aaaagatgga gatataccaa caaatgttgt ttctgactac atcattaaca
     9601 caagactttg ggcttctact caaaatcttg ctccatcatc tgatactggt ggtgatgtac
     9661 ctgacggaaa gcctacatcc gaaatcaagt tcgttgatac agattatgaa ccatctaaaa
     9721 aatctgcaat gataagagcg atcaatacta gcagttatgc cagacaaaat aatgatctag
     9781 attctaattc agtcggtatg gctctattaa aagaatggtc atcgaatgat actttcaata
     9841 ttaatactta tgccggtgat gttaatgtcg ccgaaaatga tgcttatatg ggaagagcgc
     9901 ctgctgtttg gacaggctat aatttagggg atagaaaaga aggaagtgca attaagaaac
     9961 caaccaattt aaatggatat atttggtcag caaatcaaaa tgtgacagac gacaatcgca
    10021 agcctgatgg aaaaggaaca gcgcataact ttgatgctac tcaaccttgg ggcgttgcta
    10081 acaatgcaac ttttagcaca cagtcggtag ctttattgct ccaatcggca cttgatacat
    10141 cgggagctaa gttttatgcg tataatatcg ctccttcagg aattcaaggc agtgctaaga
    10201 atatgtcaac agtaaaaaca gaatggcgta cagcatcctt agttggtcat ggagctatgg
    10261 gtaagtttgg ctcgtggcta gcgatgaacg ctgaatcaat cgttttagca gttctttact
    10321 tagcatgtgc ttgggcgatg ttcaatgtga atatcgtgaa agcatttaaa cgtgaattta
    10381 ttcggatttg ggaagtagtt ctaacaggat cacttgcatc aggagcaggt gtgatggcaa
    10441 tttcattagg tgttgttaca acatctctga tcggactaca attacctatc tttctgatta
    10501 cttttattcg tgcatttggt gatactgctg tgggattcat tcctaataca ttagttggcg
    10561 atggcgtagc aaatattgtt cgatctgcta tgattttagg tgtaggatat cttttagtct
    10621 ttaaaaaagg cgaaaaagta aataatttga ttaatatgct tattggctta ccacttgaag
    10681 tagcgtttgg gtttgatgaa cgtgctaagt tattatttgg taatagaaat gatgctgtgc
    10741 gagttgtgga cggcgtttct aaagcaatca agaaaagcca aggagctaaa aatccctatt
    10801 atgatggtgg caacagctca gtaaaagata tggttgcagg aggtcttgga gcagttggag
    10861 cgcaaaaaat ggctgaacgt ttgaacaata tgggagatag caatgctgat gctaagtcca
    10921 ttgctgataa agtaattcct gaaacaccag aaggaatgtc attcaacggt ggcggagttg
    10981 gttccacaat caataatacc tctttcaaag atttagttcg tcaagatcaa ctacgtaata
    11041 actcccaaca atatattgat catttaggac gtatggttga tgaaaacgga aactttgtcg
    11101 atgaaaatgg tgaaatatta aaagatagta aatacggtaa agatgctaaa ggcaacttta
    11161 ttgacgaaaa agggcgtttg gtcgatgaag atggaaacct tatagatact aatggtaaac
    11221 cattggaaga tagtgaagat ggtaatattg gtatggatag cgaaggacgt ttaattgatg
    11281 aaaaaggtcg cttagtcgat gaagatggaa atcttgttga cgaaaatgga cgcaggttgc
    11341 taaatggtga ttttggtcat gatagtaacg gacgtttagt tgacgaaaaa ggtcgtttag
    11401 ttgatgaaga tggaaatctt gttgatgagt ttggtaataa acttggtaaa cacagcgatg
    11461 gatataatgt gaatggagat ttagtcgatg aggatgggaa tatcattgag acgagagatg
    11521 cgcttgtggc agatcgaaat agagaactcg aacaacaacg gcatacgcca attgctgttg
    11581 caattcctga gaatgaagaa gacgagatta ctttagatca aactcatcaa gaactgagga
    11641 atgaaatgag tggtgaggac gtgtcagaca gagtgcatcg ggaattagga gatggagcat
    11701 ctggtgaaag tcagtcaaga gagcttaaca gcaactttga taatagtgct attcggaatg
    11761 acacagtact taaagacaga gaatcgctaa caaaagaaac ggataaagaa caatcagatg
    11821 tgaagaaaaa gttcattcct actcctaatg ttaatcaaac agataaatat gaaacaaata
    11881 ttggatcagg aatgtcgaaa gacaatcaat caattagaga acctgaactg acaaataaaa
    11941 ataatagaac aaataattct aaatctactt cagataattc agggaaatct aatcaatcaa
    12001 ccaagaaaac atcaacagct aaatcagccg ttgaatatct atcaaaaact ggtaaaaatg
    12061 tttacacctc agcagataaa gctttagcaa aagctccaaa aggtagtcta gcagggataa
    12121 cctatgaagc taaaaacgaa gctattaaaa taggtaaagg aacggctaag gttgccaagg
    12181 ctactgctac aggagcatcc aaaactggta aagtagtgaa gaaatctacc atgtcagtca
    12241 aggactatat tgtaaaatac ggtaatcaaa aatcaactga aaataagtct gaagacgagt
    12301 aaaaagaagg agcattgatt tgctccttct ttttactttg atttctaact gaagatgtca
    12361 aggaaaattt ctatttatgc aaaaaaatta ttttaaattg tctataaatg aattaaatat
    12421 ttactgttca aagttgta
//
LOCUS       DAFKHN010000073        12312 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFKHN010000073 DAFKHN010000000
VERSION     DAFKHN010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.073"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..176
                     /locus_tag="LY912_002173"
     CDS             <1..176
                     /locus_tag="LY912_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955831.1"
                     /translation="NREDLTGDSLDIISLIQNRSIRFQRMDPNHLKLENQDRYIDQLV
                     FTFRRLLKSDCHG"
     gene            169..573
                     /locus_tag="LY912_002174"
     CDS             169..573
                     /locus_tag="LY912_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955832.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            585..1193
                     /locus_tag="LY912_002175"
     CDS             585..1193
                     /locus_tag="LY912_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBM6955833.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            1213..1575
                     /locus_tag="LY912_002176"
     CDS             1213..1575
                     /locus_tag="LY912_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955834.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            1777..5208
                     /locus_tag="LY912_002177"
     CDS             1777..5208
                     /locus_tag="LY912_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBM6955835.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            5259..5996
                     /locus_tag="LY912_002178"
     CDS             5259..5996
                     /locus_tag="LY912_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBM6955836.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            6006..8297
                     /locus_tag="LY912_002179"
     CDS             6006..8297
                     /locus_tag="LY912_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBM6955837.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            8321..10447
                     /locus_tag="LY912_002180"
     CDS             8321..10447
                     /locus_tag="LY912_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955838.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            10464..10613
                     /locus_tag="LY912_002181"
     CDS             10464..10613
                     /locus_tag="LY912_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955839.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            10610..11056
                     /locus_tag="LY912_002182"
     CDS             10610..11056
                     /locus_tag="LY912_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955840.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            11058..11195
                     /locus_tag="LY912_002183"
     CDS             11058..11195
                     /locus_tag="LY912_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBM6955841.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            11233..11526
                     /locus_tag="LY912_002184"
     CDS             11233..11526
                     /locus_tag="LY912_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955842.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            11523..11747
                     /locus_tag="LY912_002185"
     CDS             11523..11747
                     /locus_tag="LY912_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBM6955843.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            11744..>12312
                     /locus_tag="LY912_002186"
     CDS             11744..>12312
                     /locus_tag="LY912_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBM6955844.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLA"
BASE COUNT         4311 a         1899 c         2610 g         3492 t
ORIGIN      
        1 aaaatagaga agatttaaca ggagactcac tagatattat ttcattgatt caaaatcgtt
       61 cgattcgttt tcagagaatg gatcccaatc atttaaaact agagaaccaa gatcgctata
      121 tcgatcaatt ggtatttacg tttagacgat tattgaagag tgattgtcat ggctaaaaat
      181 agttgggagc taaaaataaa tggacatgat gaacttcttg tgcggatgga acgctattca
      241 agcgagagcg aacgactgat taacgaagca ttgaaatcaa aaggttcggc tattgcagtg
      301 gataggatta cagaaaaaat tcctgtttct gaagcagatt taagaagagg gcaccaacac
      361 gcaaaaaata gtcgtccact taagactcaa tacattaatt tgggtttcat cattagacct
      421 acaagaaaat ttgagtattt aaaatatcct gatttgggga taggtacttc taaaagaaat
      481 cagccggacg aatttatgag aagaggatta ggtcttgcac ttgatccaat tacagaactt
      541 ctgattcgtc aattcgataa attaaataaa tagggggaac aacaatggct aaaacaaaaa
      601 ctgtagtaac aacgttcgat aacgtaagta tcaaacgaat tgcttttaat tttaagaacg
      661 caggaaatgc aatcgcaacg aattgtaatg gacaattaga tggcgaaaca gaaatgcaaa
      721 cggtggttaa aaaatgtgga gcgacagaag taaaatcaaa atctaaacca atcaatatga
      781 cggtaacaat tactgcacat gtaccgatgg aagtttatcg acgtttcaat gggttgaaac
      841 aagatggacg tattaaacca ggcatttact cttacggtcc tgattccgta ggcgaagatt
      901 tctcacttgc tgcagagatc gtggatgact tcgaagaaaa tagaaagtta gttggtatgt
      961 tagcatgcac ttcgaataca ggattaacat tctctattga aaatggtgcg gatgaagtag
     1021 ctgcgttaga actagaaaca aaagttatgc aagatgaatt tggtaaattt tatcatgaag
     1081 caattgttgc agaacttgaa gaagacttaa cagatcaatg gatgacgaat ctatctgctg
     1141 atgtgattaa aaaaacttca gttgtgacaa ctacggccac tcaatcacag taaaaaaaac
     1201 ggaggtagcg aaatgaacga agattactca aaaattgaac taaacgatgg aacaattttg
     1261 aatttagaac ctaaactgaa tatcaagaaa ttattgatga tcaatagaga ttttaacaca
     1321 gacgagtttg caaaaatgac tgtgggaaaa ggatccatgg atatttctgt tattcaaggt
     1381 gcaaaggctg tgtatattgc ttaccgccaa gcgaacatga ctgattatat ttcattcgat
     1441 gaatttatcg ataaatggga ttttgatatg gctactgcca gctatattta tcaattgatg
     1501 atgttcaaac aagcacgcga tgcttatcaa aaagaatttg aaaaagcaaa taaggaaaaa
     1561 aagcttcaaa agtaaaaatt ccaaagctct tagttgaaac gtgggtcgat gtctattcga
     1621 tgttgaccga cgttttttct atgccttcag atttggtttt aagcgatatc tgtttagatg
     1681 acattttgca aatggcttac aacaagagtg cttatgaagg atggaaaaac tatgcaataa
     1741 accaatccca gaaaaactaa agaaaggagg taaaaaatgg ctaaaaagag aacagaagca
     1801 gaagtaactt tcatagctaa cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct
     1861 gaattaacta aaaatagagc agaattaaaa ctagaacaag ctcaattaca acagactggt
     1921 tctgaatcag acaagttagg aagtaaatta tcttctttag aaaagcagta tgaattacaa
     1981 agtcaaaaag ttgaagtaac tagccaacgt ttagccaatg cgaaaaaata ttatggagaa
     2041 aattccaccg aagttcagaa acttgaaaga gaactgatta atcaacaaac agcgcaacaa
     2101 cgtttgtcaa acgaaattga taaaacgagt aatgcactag ctcaagcaaa aggcgaaata
     2161 cagacgtacg agtctacaat gcaacagttg gatagcgaac aaaaaaatgt tcaagctagt
     2221 gcttctctga ttgaatccga atacaaaaaa tggcaagcaa ctgctggtca atcagcttct
     2281 gaagccgaga aattagcgaa agcccaagaa tatgtttctc aacaatctga aaatgcggag
     2341 aaaacgatag atatcctaag acgacagtta gaagctacac agtctgaatt tggcgctaca
     2401 tccacagaag caatgcagat ggaagcgaag cttaatgatg ctgaacgtga atttgaagag
     2461 ttaggacaag ctgctaaaaa tgtagataca actaacttgg acgatatcgg aagcaaaata
     2521 gatatgaata atttaatgga agcttctgac gttttaagcg acattggcga taagcttaca
     2581 gaattaggga aacaagcagt ggactctgct aacagtgtag gtagttccca gagtaagata
     2641 caagctaatt ttggtttgtc taaacaagag gctgaagaat taacgaatgt agccagagac
     2701 atttattata aaggttttgg agaatcgtta gatcagtcca cagatgcatt gattttggta
     2761 aagcgtaatt taggagattt aaataatcaa gatttacaaa atatcacgga acaagctatg
     2821 gtcctagaaa acaccatggg cgctgatatg gatgaaacgt tacgtggtgt aaatggctta
     2881 atggtcaatt tcggcttgag tgctcaagat gcaatggatt taatggtttc gggtactcaa
     2941 aacggtttag ataaaacgca cgaattaggc gacaatatgg cagaatatag ccaattatgg
     3001 agtcaaatgg gatattcagc tgatgaaacg ttcggaatgc ttcaaaatgg tttagatgcg
     3061 ggtgcttata accttgataa agtcaatgac ttagttaagg aaatgggaat atcgttaaca
     3121 gatggtcgat ttgagcaaaa catggatatg tttagtgaaa gtactagaaa agcttttgaa
     3181 gagtggaaaa atggcggagg aacacaaaaa gacgttatta attccatgat tcaagatttt
     3241 agcaatatgg atggtcaata cgaccaatta aataaagctt cgacaatttg gtctgcgctt
     3301 ggcgaagata atgcgatgaa agttgtccaa tctttaactg atgttaacca tacatttgat
     3361 gatgttagtg gatctgcaca aaaaatgaat gaagattcta ctactccgtt gcaagagttg
     3421 aacgggaaaa tagctgaatt aaaggattca ttagctccta taggcaacac aatcatagat
     3481 gcactcgaac cagtaattga ttttctagga aagatggctg atgcgtttaa taatcttcca
     3541 caaccagtac aggatttcat tgttgctata ggtggtctta cagcagcatt tggcatactg
     3601 ttaccggcaa tactagccgt gtcatattta tttggtccga tgatgcttat aattggagga
     3661 attatagctg ttatagcagg cgttattgtg gcaattaaga actggggtgc aattactgac
     3721 tggtttagtg gtttatggaa aaaatttact gattggttgg gtgatacttg ggaaagtata
     3781 aaagacggag cctcatcagt ttgggatggg gttaaagaaa cctggtctgg atttgtagat
     3841 tgggttcaag atatttggca aggagtttct gattggtttg gagagctatg gagcggatta
     3901 gttgaaggag cttccaacat ctggcaagga gtccaagaaa cttggcaaac attcgttgat
     3961 tgggtttcaa atatttggaa cggagtcaaa gaagtatggt cgattatttg ggcagacatt
     4021 gtaggaattg ttcaaatacc atggacatta ataacgtcat tgattcaagc tggtattaat
     4081 attatcgtgg gtatttttga tgtagctgga cagttattgg gcgcagcttg gcaagctgtt
     4141 tggacaccta tttctgattt ccttaaaaat acttgggata ctatgacaca atggataagt
     4201 atcgcttgga atgggattgt aactacattc catactatat ttgatccagt agtggcatgg
     4261 tggaatggta tatggacagc tattagtact acggcttcaa atatttggaa ttcaattagt
     4321 gcaacagctt ctagtatttg gaacagtatc aagaatacaa tcactagctt ggtacaagca
     4381 gctgctacag taattcaaaa tatttggtca actgtatcta gttggttagg tggaatttgg
     4441 aattcaatca gctctacagc atcaaatatc tggaatagtg tgactagtag tataagcaat
     4501 gctataaacg cagctaaaag tgccattcaa agtgtttgga atagtatatc ttcgtggatt
     4561 agcggaattt ggaacggtat caaaaatact gctttgaatc tttggaatgg aattacaagc
     4621 actattagct ctaaagtaaa cgatggaaaa aatgcaattt caagcggttg gtccaatcta
     4681 acaggtattg tttccgacat attcaataat gttaaaagta caattgctaa catatgggaa
     4741 ggcatcaaaa agactgttag cgctccaatt gattggatta gagacaaaat cagtggcatt
     4801 tttgataatt tgaatatttc tataccacat attccgttac cggaatttat catggaaggc
     4861 agctttaacc cgctaaaagg tcaaatcccc catttgcgtg taaaatggca tgctaaagga
     4921 ggtatcttta ctaaaccaac tttactaggt ggaatgaacg gtgtcggtga agcaggacct
     4981 gaagcagttt tacctttgaa aagatctgtt ttgcaagaaa ttggtgatcg tatcttgagt
     5041 agcacatcag tttcatctag ggcacaaacg attcaacctg tgaataacta cgaattcaat
     5101 ttcacaattg atggtaacgc agatgaggtt actatgaagc aaacaactca acaaatcatt
     5161 gatagcatta caaaaattca aaatgataat gcttcggcat ggcgttaaac aggagagtat
     5221 ttctcctgtt tttttagtat taaaaaggat gtgaaaaaat gactgattgt atacattcta
     5281 taatcgatgg atttcctgat tatttgcata aattggcttt agctgaaaga ccaaccatac
     5341 cttctccaaa aagacagaga gttgaaactt ctgttttagg taggttaggt ggcttagtac
     5401 aagattactc gtttgaagat atgtcgttta cattgcacta taactattta gaggatgtgg
     5461 aagaccatca agcgttcaag caatcgtttt atatcatgcg tcattggtta aactatgcaa
     5521 agaaattaga attctctgac gatcccaacg tctattacgt tatccagact atcgatattg
     5581 gggatgcaga aaacgatatt gttgaatggg gagagttcga tgtaaatatt actgcgaaac
     5641 cattcgcaag agttcaagaa gatgtaccta taaccgtaga taaaccacag tcatttaact
     5701 tgctgaataa tagtttagaa gaaagttttc caaagattat catcactcct tcagctactt
     5761 catgccagtt catcttaaat gattatgtgt ttagtttcga aggcttagta gcaggaactg
     5821 atgtagtcat tgatagtgat ttgatgcttt gctacgaaga gcaatcggac ggagatattt
     5881 tagatcggtc caacaaaatg aagaccatgc aatatccgac attgcaagtg gatatcaatc
     5941 attttaattg cactggtttg agcaaaatac aaatttatcg taacgggtta aggtaggtga
     6001 aatagatgat cgataattta ataactattt acgataaaaa tgacgcgaat aatttagctg
     6061 aacatttata tgatacgcaa ggtttaggcg ctttgtcaga ctggttaaca gctactgtta
     6121 gcaataaact aaacggagcc gagatatttc agggtactta ttcaataaac ggaactaatg
     6181 cagatttgat tgtagacgga cgtattattc agtgttatgt agatgaaaat cgagcaaaac
     6241 agcgtctacg gatttattat gcaaaaactt ctgtaatagg caatacgata gaagtaaaag
     6301 ctgaacctat tttcaatgat ataagaaaat cggtgttgaa taaatatgac agcggaacag
     6361 aaaagatcac tgctactcag gcatggcaaa acgcaaaagt tttagcgaaa ccagctatcc
     6421 cttcgcagtt ttctttctcg tcattagtag atacgcttgc taatgtgaag atagaaaagg
     6481 cgaatttttt agaattcttt ggtggaaaag agggatctat tctagatcga tttcatggtg
     6541 agtttctaaa agataataac acattacgtc atgaaaaaag tctaggtacg gatcataaaa
     6601 tcaaagcgat ttatactaaa aacttaactg gtcttgactt agagattgat gctcaaagtg
     6661 ttttagttgg agtttatcca ttcattagca gctcttcaga aggagaagac gagatcactc
     6721 taccagaaga agttattttc acggattacg tggatgatta tcctgctgga tatgtttctt
     6781 ttgttgattt taaagacaaa gcgactgatg tagccacatt aagggaagct gctaaagact
     6841 ggttgaaaac aaacatagat aaacaaaaac cacaagtgag tggttcgatt gaattagtac
     6901 cattgaggca tcaaagaggc tatgaaaaat ttgttgatct agaaaaagtt tcgatgggtg
     6961 acggagtaga tgtgtatcat ccacagttaa aagtgaatat gtcagcgaga attgtggaat
     7021 atacgtttaa tgttctaacc aattcatacg ataaattagt tgtaggaaac gtcaaaacaa
     7081 acttcttaga aaacacagag aataatgtca gcaatttgat taatgatgcc attgatcaat
     7141 tgaaaaacgg tggcgaaatc agtgatttac tcaatgatat tgtagatcat caaactgata
     7201 tgattactgg tcaaaatggt ggttatgttt tattagatcc taaagaagcg cctagtcgta
     7261 ttttgattat ggacacacca gataagaata ccgcaaggaa tgttttacaa atcaacaatg
     7321 ctggtattgg tttttctaaa actggcatta atggaacata tgaaacggca tggacgttag
     7381 atggcggatt caatgcctcg tttattacgg ctggtgaaat agtaggaatt actattagag
     7441 gtactacatt aattagtgat ggtgctgatt atagaacaag tattgctaat ggcaaaatga
     7501 cttggtactc aaaaaaagtt aacaaagata ttatggagct agaagcacgt gattatgtaa
     7561 gtgctgatgc cggtattgta tcatacacca tgaaaactgg tggtggtttc atgattagaa
     7621 atccacaggg taacttggtt tttagtacgt gggataatgg taataacaga ccgtttctat
     7681 cttttggtgc gcccaatttc aggtatagca atgctagtta tgtaacttct ggcgacggta
     7741 gttctttaag cattaatggt agtgcgggta actcatggga atttaaggta gctggtagga
     7801 ctatgaaatt tactagtgat ggtatgctaa cgttaccagg ttgttttttt ggttcatggg
     7861 aagatgggaa acttgctagg tttgaacaat caacggtaca agtatataaa gattttactg
     7921 ttagaggtac taaaaactca actgtaccaa cagaacatta tggacaacga ctattgaacg
     7981 cttatgaaac tccagaatat tatttcgctg attatgggga agccgttaca ggtgacaatg
     8041 gtaaagttcg tgttgatatt gaccccatgt ttgctgaaac agtaaatcta agtcggtata
     8101 tgacacatgt gacacctaca gaactagttt tgtgtgctgt tactcatgaa gatattgacc
     8161 atttcatcat tgaaactagt aagccaaacg tattagttag atggaattta gtggcacacc
     8221 gtctagggta tgaagatatt agattaaaag aggatacagc atatgatagc acagtgcttg
     8281 accaaaaacg tttttaaaac gaagacaagg aggtatataa atggctagca gtttatataa
     8341 tttggcttta gatttcagca aagaattaaa ctacaccaaa gctattatgg ctcgtcaagg
     8401 tgataaaggg attacggtga cggttaaacc gtttctaaat ggcttgcaga tggatacgag
     8461 tggcggaaca tttactttaa aaggaacaac accatctaac cgttacgtag ataatgttgc
     8521 aactagtgta actagtgaag aagtcacgtt ttctcttgat ggcacattta tgagtgaagc
     8581 aggatattat aaacactgct acgtagaata tagaaaagac aatcaaattt taacaacgca
     8641 agatatcatt tttttctcac taggagtgtc tgacatttcg caaggccaag ccgatgaata
     8701 tgtttcgcaa ttagaagagt tgattcgaaa gtacaacgaa acttttgatg cttttatggc
     8761 tgaaatcaaa ggtagagtgg atagcttaaa tcaacagatt actgatttaa ctggtcaagc
     8821 taaaacgcta caagacaagt tagatgctct gaaagaagaa atttctaagt taggtaactt
     8881 acaagtgatg tacagtaaca gcatcgactt cggggactat gattattcgg agaacccgaa
     8941 tttaatgcca tatattacag aaccttgggt tggacctttg ttaggtaatg gacatacagt
     9001 taaagatagt gttaaaaggg ttataactca tactaaaact agaacagcta attccggcga
     9061 catattatcg cttggcttag gtattccgtg tacagcggaa gctaataata ggtatcttat
     9121 aaccacttta cgaccatcta cgacatacac attaagcgtt actatgagtg tcggttcaga
     9181 ttggactgga gagaccaata ctataggggt taggcttaga tatttaaatg aacaaggtgg
     9241 tatagaactg cccattaatg cattaatacc agcaaatgta gaacgcgata aaatggtcac
     9301 tcatacattt actggtataa caaaagataa tgtaactagc ataacaaact gttatgttga
     9361 aatattctca cttaatagtg aatataaagg aacggttagt gtcagctatg acgttaagtt
     9421 aaaagcacac taccctaact tactagatgg cccttactgg ttaggtaaag ttcctttagg
     9481 cgagaatatt gctgacccta cagttgtctt tccacacaaa actagtgaat atatggttta
     9541 tggtagacgc aatacagaaa actatatcgc tgaccaaaca tataccatat caatgaaagc
     9601 aactaaacta acagttcaat cgtttgccgt gtatattgct gctggccgcg ttaaagtagg
     9661 agacatgaag cctactgagg ggttagctaa tacatgggag ttaactttta ctgtaactaa
     9721 gcaacatata gatagtgggg taactaatta tctggaaata taccaatacc cgtcagctac
     9781 aaaaggagct gttcaaattg agtggctcaa actagaaaaa ggcaatactc gaaccccgaa
     9841 tattagtgag tataaatatc gtggtactgg tatgcgtgat tcaaacaatc caaaagatta
     9901 tgtttgggat ctagcaccag aatatgtcga agataatttg gccacagata ttaaaatttc
     9961 tgaaattact ggtaaagcaa acaattatac cgatgggaaa gtatcggaga ttaattcgca
    10021 gttgactgct tcaattaatg aagtagacac cacagctaag gatgctcaaa caaaagcgaa
    10081 tgctaatgcg actgctatag atgaattaga caataagatc gatgaacgca ttaatgatac
    10141 agctactacc acattaacag ttacaaacgg gaataccgga tcagcaaagc tttatcgtga
    10201 aggaaaaaca gtttctatat attttgtggc tttaaacgga aaaagcagtg gtggaaatga
    10261 ttcaacgata ctaacaattc cagaaggcta tcggccacca attagttttg agcaactggt
    10321 tggctcgata gaccgttcta ctttgaacag tgctcagtta tctattggtg cagatggagc
    10381 cattaaatgg cgaagaaact caagttatgg atcggattat acctttgcaa ttacttacac
    10441 gatttagaaa agcgtgaatc gatatgaagg cagcatatag accaattgaa ccttacggat
    10501 tcgagcaaat cattgtgaat gatgaagaac atttaccgga agaatgcaca gaagtcgaac
    10561 caccgattcc aaattggaaa ccgaaattca attactggga gggaaataaa tgaaaaacat
    10621 ttggaaatat ggacgtactg gcggagagta cgcaggaaaa gtattggacg acatgcttgt
    10681 atccgttcct tacacagatc agccaccgct tgaaggaatt cgtgctgatg gcgaaccgtt
    10741 aacaatcgct gatcaaatgt ttgatcctaa attgaatcaa tggattattt tagcgaacgc
    10801 actagatcac aacgatttaa acaatctcaa agcaatgtat gagtcgttag aaaatgagaa
    10861 cggcgattta aaacagatca atgccaaact catgctaagc gatgtagcaa ttaaacagga
    10921 aaatactgca ttgaaagaaa aagcggatag tttagcacaa atcaattcaa aaatgatgct
    10981 tgcttcgtta caaaatagca aagacatttc agaaattaaa gagcaactaa atccagcttc
    11041 aaagggaggt gagtagtatg tttagtttta gcgatgtgaa aatgatgtat gattggggct
    11101 gtttcactaa cgaacaagta atggttttcg ttccgttgtg cattactgaa gaaaaagcag
    11161 ataaaatcat tagcaaagaa gagagcgcat cttaattgat gtgcttttta ttttgattca
    11221 aggagttgtc acatgattaa tttaggggaa tggggagcga tagcaggatc aataaccgct
    11281 atcgtttctt tgattttatt agtaataaaa ccaattactg catctttctc gaagattact
    11341 gagactcttt caaaagtaag tcacaattta gatttgctga ctaaagattt agaatcgagc
    11401 aaatcagatc gattgatgat tcatgaagaa ctaaagaaac acgatgaaag attagataca
    11461 catgcagaaa aattggtaga acacacgcaa caaattaaaa ctttatttag ggagagaaga
    11521 aaatgaataa taaaacgttc gaagtactaa aatggttcgc actggtaatt attcccgcac
    11581 tagctacttt cgtggggtta gttggtaaag cgctcaattg gcagtacaca gatatctgtg
    11641 ttgtcatcat tactggtttt ggcgcgtttt tagggagtgt gttgggtgta tcaaatcgaa
    11701 cctacaaaat gttctcggct gaaagcgaag aaggaggaaa caaatgaaaa agaaaattac
    11761 tattactgcg atgagcctgt taacggctct ttttttatta cccattaata cgtttgctta
    11821 tactattaat gacgagtata atttagcgcc gaatcaagga gactccagat tagcaattcc
    11881 taacaaaatt attttgcacg aaactggaat agatgcacca gcaagaaacg tagccgccaa
    11941 catgaaaaat aattataacg gaagcaattc ttatactaca gatgttattg gtgacggtgg
    12001 gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg ggagctggta acgctaatcc
    12061 ttatgcgcct gtacagattg aattacagcg cacatatgat aaagcattgt ttgaaaaaaa
    12121 ctatcgagct tatattgaat atacaagaga tagtgcaaaa aaatatggaa ttccattgac
    12181 tcttgatcaa ggaacttctt tatttacaaa aggaatcatt tctcatttgt gggtgacaaa
    12241 ttatgtttgg gggaaccaca cagatccata tggttactta tcgcaaatgg gagttagcaa
    12301 agaaaagctt gc
//
LOCUS       DAFKHN010000074        12136 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFKHN010000074 DAFKHN010000000
VERSION     DAFKHN010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.074"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..610
                     /locus_tag="LY912_002187"
     CDS             <1..610
                     /locus_tag="LY912_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBM6955845.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="LY912_002188"
     CDS             723..1001
                     /locus_tag="LY912_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBM6955846.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="LY912_002189"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="LY912_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBM6955847.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1458..2213
                     /locus_tag="LY912_002190"
     CDS             1458..2213
                     /locus_tag="LY912_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBM6955848.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="LY912_002191"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="LY912_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBM6955849.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="LY912_002192"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="LY912_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBM6955850.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="LY912_002193"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="LY912_002193"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBM6955851.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="LY912_002194"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="LY912_002194"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBM6955852.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="LY912_002195"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="LY912_002195"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBM6955853.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="LY912_002196"
     CDS             6950..7492
                     /locus_tag="LY912_002196"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBM6955854.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /locus_tag="LY912_002197"
     CDS             7515..9071
                     /locus_tag="LY912_002197"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBM6955855.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="LY912_002198"
     CDS             9085..9987
                     /locus_tag="LY912_002198"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBM6955856.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="LY912_002199"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="LY912_002199"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBM6955857.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="LY912_002200"
     CDS             11430..11852
                     /locus_tag="LY912_002200"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBM6955858.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4035 a         2155 c         2677 g         3269 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttattt
//
LOCUS       DAFKHN010000075        11516 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFKHN010000075 DAFKHN010000000
VERSION     DAFKHN010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.075"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            180..386
                     /locus_tag="LY912_002201"
     CDS             180..386
                     /locus_tag="LY912_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBM6955859.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(588..1589)
                     /locus_tag="LY912_002202"
     CDS             complement(588..1589)
                     /locus_tag="LY912_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBM6955860.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1594..3507)
                     /locus_tag="LY912_002203"
     CDS             complement(1594..3507)
                     /locus_tag="LY912_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBM6955861.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3675..4181)
                     /locus_tag="LY912_002204"
     CDS             complement(3675..4181)
                     /locus_tag="LY912_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBM6955862.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4341..4781
                     /locus_tag="LY912_002205"
     CDS             4341..4781
                     /locus_tag="LY912_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBM6955863.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(4807..5964)
                     /locus_tag="LY912_002206"
     CDS             complement(4807..5964)
                     /locus_tag="LY912_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955864.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(5967..6323)
                     /locus_tag="LY912_002207"
     CDS             complement(5967..6323)
                     /locus_tag="LY912_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955865.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6621..7595)
                     /gene="sgrA"
                     /locus_tag="LY912_002208"
     CDS             complement(6621..7595)
                     /gene="sgrA"
                     /locus_tag="LY912_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBM6955866.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(7791..8630)
                     /locus_tag="LY912_002209"
     CDS             complement(7791..8630)
                     /locus_tag="LY912_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBM6955867.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNRTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            8815..9702
                     /locus_tag="LY912_002210"
     CDS             8815..9702
                     /locus_tag="LY912_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBM6955868.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEGAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(10296..10991)
                     /locus_tag="LY912_002211"
     CDS             complement(10296..10991)
                     /locus_tag="LY912_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBM6955869.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(10975..11373)
                     /locus_tag="LY912_002212"
     CDS             complement(10975..11373)
                     /locus_tag="LY912_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBM6955870.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3434 a         2300 c         1726 g         4056 t
ORIGIN      
        1 ctagacgtat gatggtaaac tttgtaccta tctgattgct gaatcattaa ttgcttatca
       61 ttagccatct ttgtttcaag ttcgctagat gatcatttta ttcacatcct aacaaacttg
      121 tcacatttat agattcttaa tctatttatc atacaattat aaaaaaggag gtgctgctta
      181 tgaaagctat ccatatttct ttgctttttt tcgctagtgc attgatttta tttgctattc
      241 atctttgttc ccagccttat atcaataaca acggaatatt agtggaacca gcattctttt
      301 gcttaccact cggctttttg tcccttcttg cctccgcagg cttcggattt gttgcttttt
      361 ttaaacgatc aaaacaacaa atctgactta taaaatttac gtaaaagaga tcgtgacaat
      421 aatcgtgtga tattcccaaa tttcgaataa aaggtgcccc ttgccatctc taactcctca
      481 gtcacaagtt acaatattca taaaccatga aaagcttgtt tattgaaatt gctccttgtg
      541 acttggagct aagtgacaga ttacaacctc ttttgcatca taagacttta ctccttgaaa
      601 aacattacta acttttgata tgtttcttgc gcttgtttat tgctgaaatc aaactgatat
      661 tcatggttca aaacagcatt tttctccgca taatctactt ttgtgacttt cacccccgct
      721 ttctcaaata cagaagttac ttcttccatt tgtttcgtaa acgtatttgt atttccatcc
      781 gttaagaatg tgttttgcgt ccaacgatcc gcatgtctga ccaaggctaa acttttgacc
      841 ttctctgatt gttcaaagtc cttattatca aagtaagccc atccacattt ttcataaaga
      901 aagctagaga ttttatcact tacttgagta agtgcagaag gatccaacag accagacaaa
      961 gaaataaact tcgtaatctg cttgttctcc aaagtcggat caagatgatc agctttttta
     1021 atttcttcat tttgaagtgc taacaaatat tctccactaa tttgtgcacc tgccgaattt
     1081 ccaccaatcg aaatattcga ccaatctgct tgatctttta tctctttttt agctgcttga
     1141 atggcttcgt tcaattggat aactggtgta ggatgttttg cttccggtga tcgttcataa
     1201 tctatattta cgatgatttg ctgcgtgtct gaacatagat attccaaata atcacgacaa
     1261 tcatttttat cccctcctac atatgcgcct ccatgcatcc agaaaagaat cggtaatttt
     1321 ttcttttcca ctttcggtgt gtagatatcc atattattat ttttgtactt tgaaggatag
     1381 gatatttctt tttttatatc gatttgttcg attttttgct ggaaatcatc tggtcgggca
     1441 tatacttgtt ctttttcact tgtgtcaaat tgttttctaa caagcaagct aatcggcttt
     1501 ggtgtgattt gattaatcaa aaatacagtg actaaaataa ctacgatgat aactggtact
     1561 gcaatcacta ttcgcttgaa ccatttcatt catttaccct ctctttcttc gccaaatcca
     1621 tgtgataatc gtgctaacag ataaaaatcc acctgaataa atgagaagcg aatgtttctt
     1681 ttctccagtt ttcggcaaca ttcttttttt tgcatctgtc tttttttgta ctttcactgt
     1741 catctgaatc ggttgcgtat catcacttga ttgatcctct cgaggttcat tctttccctt
     1801 attgtctgca ttctctgtcg gatcttgctt ttttggtgga gctactggga tttttttgta
     1861 atagaaaata atagttggta tcgtctcatt aaaaatccct tcagtcggtc cttcaacatt
     1921 tgctaattcg tatccttcga atgtcttttg ctctgtcata taattttctc cataagctcc
     1981 gtaaagctgg atttcgtcct ggtctttgag tagactttta ttgttttcat ccacatactt
     2041 tacgtttatc tgatcatgga acactacttt caaaaagtcc gttacatgtt tcgtgtaggc
     2101 agcatggtca acttcctgtg cctttccatg ccctgctcct tctactaata aaagatcttt
     2161 ataccctcct gataactcat ataatttttg cgcgttagac acaggtacta catcatctgc
     2221 tgttccatgg ataatcaatt taggcaatga atctgacatt ccaatcgtag gtagagcagc
     2281 ttttgtatcc aaatgcatct cctgatcaaa atagtattgt ttcaaaaggc ccataaataa
     2341 atcttcatgc tcttgatccc caatgatgtc taactgattt tttatggcat ccggtagtgc
     2401 gggggctact gtctggctgt acgtaaaacg tagttgttca tcaattgatg caaatccgca
     2461 attttcaata attcctttga cattgacagg aatatctttc gctaatacag acatcatcgt
     2521 agctgctccc atcgaaccac cataaagtaa aatcttttga gatggccgct ctcgaacttc
     2581 ttgatttatc cagtaaagga cgtcatctga ctcatattgt ccataggtca cataatcgcc
     2641 tccgctatta ccagtcgctc tggaatcaac aaataataaa ttatacccgg ccttataaaa
     2701 atcattgtat tcttctgtaa cgatcccgtt attccaattc cctcgaaatc cgccatggat
     2761 catgactgtt ttatctgaac cttgatcgac ataatatgca tatacatcca tcattttgcc
     2821 atcttgtttg tttagtacag tttgatgaag ttgttttgta tttggataga agcctgtgtt
     2881 ttctgtaggc gttgtcccat catctgtacc tccaagcatc gacatcaaca cactgttttt
     2941 tgcaaaagcg atatcgtaca atagataagt agcaatcaga tgtttgataa tctctttatc
     3001 tacaccataa tcattaacag caagctcagt gactaataac tctattaatt ttgacttgat
     3061 gtcttctgtt ggtccattaa gtatttctgt catctgttta ccgaagtaat tcaaatattc
     3121 tttaccattg aaattttcac ctttaccgat atcatcattt tctgtcccat tctctttgtc
     3181 acttacttta gcagaagagg attcgtcgtt tgacattttt gtagctgttg cttcttctgt
     3241 ttgttggtta tctgtggtag cggtcgtttc ttgatctgtg ctagtaacag atgtctcaac
     3301 cgttgtttca gtatttgttt ctgtttgtga agtactcgat ttcgtttcat ttccagcatc
     3361 agtagtttct gtggtttcta cctcccgaga ttccgattcg gaagaaatgc tctctccata
     3421 tactgtccat tgcgggacgc ttgtacttac agcaaataag atgaccaacg ctccctttaa
     3481 tacttgtttt gttctcaagc tattcactcc tttttatgtt tctaggagaa ttatatgtaa
     3541 acgcaaacat tttttataca aaaaataaat ggtttatccc ataaaaatag aacaggatta
     3601 ttttctcatt ttacgtaata aagcagaatg gataaaccag tatccattct gcttttttta
     3661 aacgaagaaa caacttattg ctccaaaaat gtcagaaatc gtttatccca aattttctcg
     3721 taaaaagcga ttgtttcctt tgctttcata aaaggattat cataagttgt cgttgctcct
     3781 ctacacatca taagctggta tcctaatcca tgagcaaact tcacagtcgt atctatacaa
     3841 tactctgctt gtgccccaca taattcgatc gaatgacagt ccaattcagt taataaaaca
     3901 ctcaaattag tcttataaaa tgaattcgca tgggtttttc tcacaaaata actgtgctca
     3961 ggaatagata attccgacaa tagctcccat ggttttgttt gtggcactaa ttgagcatct
     4021 tcgtgttgaa cgaaaataac tggtttccca atcgtttcgt atgttttgat tcttttattc
     4081 actaatgctg tcactgtttc taattcgtgt atcggcgaag aatcaaaaca tacccctttt
     4141 tgtaaatcga tcactactat tgcgtcggct gtgtttgaca tacttgtgcc ttctttcttt
     4201 tttcttgatt taatagtatt tcttatctag ctagttccat tatacgtgac aacattttct
     4261 tattttacac ctctaaatgg cacttttcga ctatttcttc atgttattat ttcataaata
     4321 cttagctatt ggaggaatgt atgatgatta aattgtatac aggttctggc tgctcgtctt
     4381 caagacgcgc aaaacgttgg cttatcgtcc atgatatacc gtttatcgaa cagaacttaa
     4441 ttcgtcaacc actaaccaaa aatgaattta tccacttact aaaattgaca aacaacggcg
     4501 tgaccgaaat gctctctact cattctatta gttataaaaa tcttgttcac agaatagatg
     4561 aactcagttt gagtgaacta tatattgaga ttcgtacatc cccttcttta ttgaaaaaac
     4621 cgattatcta cgaccaatct gcaaaacttt tgactggatt tagcgaagat aaaatcagga
     4681 tgttcctttc taaaactaaa agaaagcaag agctcaacga actcttgctt tctggtcatc
     4741 ttgtcgattt taaagaaaat aatctttttg caatgtctta attttggcat aaacaatctg
     4801 cttttcttaa ttaacgaaat ccaatttttc caatatggat ctatttttct cattcctgat
     4861 ttttatgatt tcagctttca gacgcgccca atcatttttt gtaggttgtc cattccagta
     4921 aaatatctgt gtattcgttt gatcatatgc ctttttgtcg ataggataat cgctaatgac
     4981 aatatcaggt aactgatcag cggatgcact atattttatt gggcgttcag tcatagataa
     5041 tatccttttc tttgcccata attcctgtgt tttaccatac tttgattgaa tatagaatat
     5101 gacaggttgt tcgtgtttta taaaaatatc cctgactaac atacagtatt gaaaaatcaa
     5161 ccgtctgttc ttttcataat aagtattaag ctctggaatt ctgcgagcta ccccactaaa
     5221 aaactgttgc atgattggat acatcactgg aaatatatgc tgaaaatctc tgtcttctgc
     5281 tgattttcca aaagcatcca ccttcttttt tgtcccaaaa acccttgaat acaaatggat
     5341 cattgccaaa ttgacatata gataattttt ttctgaagtt gtaaaacaaa tcttgaagtt
     5401 tttttcaaaa ttttctacaa tagacgattc aatccagccc caactttctt gtactttatc
     5461 tggagtatcc aacaaatctt cttccaaata ggtgttcatt acaccaaaca taaaataaag
     5521 gtaagcttgc tctgttggag tgatgtgatt catcgaccag aagtttgctt caaaaaaagg
     5581 ctctagtatg taatgcgtaa actcttcttt tgttatcaat ggatgcacaa atttgttcat
     5641 ctcttctggg acatacgtaa tcgagtggcc ttgtttcatt cgttgcaacg aaattcttag
     5701 taggctgatc catttctttc tatctatact acgcgtatat ggcgcatgtt tcgcaaattt
     5761 ttctaatagt tgacgtttat tttttatact tgataatata tcagaatgat tttcgtcgaa
     5821 tgactgccaa tacatcaagt gaaaaaagta tcggatacgg tattcttctc cttctatcgg
     5881 attacctttt ttcaagctgc aagataaatg atagtttttc aaaatagtat taagttctct
     5941 taattttctt tgaatcgtac gcaaacttat ataatttttt gactaagatt ttctaaggat
     6001 tgataagtac ctttgtaaag tgaatccagt aaaatataac caatcgttcc ctctaaaagt
     6061 atagaataaa ctttactcag taaaaactga gaagaaaact cgacttttat catcttgttt
     6121 tctgaaagaa aagataattt atattctgga tacctttcgc aaaacgattc tgcttgttga
     6181 atcaccgaat tcatcttagc cagggtgtag tttagatcta aagcgatatc cttcaccaca
     6241 tataatttct cgtctctttc ataacaatag ttcaaaaatt gatatacttg cctttcattg
     6301 atatcaataa attcttcaaa caaagtacat actccttttt atctattatt tagacttatt
     6361 ccgacagcta catgaataac gtacaaatag attcgttact gatttttcag agatactacc
     6421 atgcgcagtg tgcattgtca attattcttg ctcttatttt ccatttgtgt tcctgttatt
     6481 tcctgtttct caaatatgtt agtaaacaaa aatagatctg gcaaagctac aacttcgcca
     6541 ggcaatacag cactctcgaa tgaaatattc actcaaaaat ctatcgtttt attcaatttt
     6601 agatctgttg cttttattct ttatttcact cgatggaaga gagaacgaaa atagcttgct
     6661 cctacaatca aaatgagtaa cacacccatc catgtaatta gcttgttcaa ggttctacta
     6721 ccagtttctg gtaaatcgct ttttctatta tctgtttctt tcgctttttc ttgatgatca
     6781 attccacgag aaacaaaatc aggctgtttt agcacacttt ttaggttgct ccctgcattt
     6841 ctcttttgtt ccttagttgg tatgataggt accaaatcaa gttcattatt tacttttcct
     6901 gtgctgcttt cgctgctcgt gcttcctgtg ctactctcac tactcatgct tcctgtgcta
     6961 ctttcactac tcgtactctc cgtactgctt tcgctgctcg tgcttcctgt gctactttca
     7021 ctactcgtac tctccgtact gctttcgctg ctcgtgtttt ctgtgctact ttcactgctc
     7081 gtactctctg tactgctttc accgctcgtg ttttctgtac tgctttcact acttgtgcta
     7141 tccgtactgc ttggcggtcc aacaactgtc caactgcttg gtttcaaatt ctccgtgatc
     7201 gtcatctgtc catcataaaa aacaatcaaa tcaactttat ctttactctt gatctcatca
     7261 atcgatagtt ctgcagaaat cattattgta tactcaatac cagcggtcca ttgtacgtct
     7321 tttaaataaa cttccccaat aactttttct gaacttccat taccatccca accatatgtt
     7381 agaacagcat gtacatcact agcattcacg cttttgtttg gtttgactgg aatagtaatg
     7441 acttgttgtg tcatgtcata aacaatccga tcagttttca cagtaaatga aagattctca
     7501 tttgcccgtt catttgcaga agtactgatt ccaatcattg ctgcaattat actcagccca
     7561 agaataacaa ataatacggt cgctgttttc ttcatttcta tcactctcca tataattacc
     7621 ttctatttga taaaggaatt atataaaatg aaaatgatga gaacacgaca gtcagttgtg
     7681 aaaatctaac aaaagatgtc gtgtattcgc ttgaatttgt ttactttttc gtttaatcaa
     7741 tgacagactt aaaaaagcaa gaccgatatc agccttgctt tcttcatctt ttattgataa
     7801 acagcagtgt atttcttcat ccgctttgtt ttatatgcat agagtaacaa accaacaatc
     7861 aagactaaca agaataatgt agttgatata gatgcttcag ccccaaagtt tcccccagta
     7921 attattgtat tttgcgattg gatcagagtg gagaaaaaac cttgttcttg cgttccgctg
     7981 actggtatac ccaaaatagc tccttgtgtc cgattccaag taatatgagc accaatagcc
     8041 gtaaataaac ttcctgtact gtagataagt gcgctgaaaa agcaacctgc taaaaagata
     8101 ttgaaaactg ccagaaatgt catgttagga ttcaatccgt gcaaaagagc aaataatgca
     8161 gcagatccaa tcattgctat taacggacca aatctaagca tctgatgctg aaaaaagcca
     8221 cggaataaaa gctcttctga tgcccccact gcaataaata aaataaaact cgttatcagc
     8281 ggcacaatgt ttgcgtttcc tgaatctaac cgatacgccc ccgtcaaata taatggacta
     8341 gtaataagca gaaacactcc aattccaaca acgagacctc ccgctaaata cccccagtct
     8401 tttcctcgaa cagaaacacc ataatcttct attctttttc cttcgacctt actagcaaga
     8461 aataaagcta gtaaaaaaac agctaaatgt ccgaccgtac cggcaattgc tccaatccat
     8521 tcactatttc caataaacat atccgcaagt gcattattga caagaattcc taaaacaaaa
     8581 ccaactaaga ctattaaaac agatccaatc aaccgaataa tcctgatcat ctttcatccc
     8641 tcctttatat taagtttaac aacccttttc tttcttgtct cgtgaaaact atgtaaatgt
     8701 tctccatcat agagagaata gatttttacg aactaagaat atctacagca accttacgaa
     8761 aatgaaagac tgtctcccta attcttctgt tagactgttt ttaataagga aaggatggga
     8821 aattttttga aaaaacaact actaattatg tgcctttcag catgtgcaat tttactattc
     8881 tcaggttgta gcaagtccaa tgaaacgatt gcaacgttta aaggtggaac acttacagtt
     8941 caggattttt atgataaccc aaaagttaaa tcaaataatc aaacactatt aaaaaaaatg
     9001 attgtcttca aagcatttga tgatgtatac ggaaaagaga tttcttcaaa ggaagtaaca
     9061 aaagaatata atgaacaaat caaaaaactc ggtccaaact acaaggaaca attaaaagca
     9121 gttggccaaa cagaagagac atataagaaa ctctttaaac agatgctggc tttccaatac
     9181 ggtttgaaag ccaatgtaaa attaacagat aaagatctag acactgcttg gaaagaattc
     9241 tatccagaag ttagtacaca gatcattcta ttttcgacta aagaaggagc agataaagca
     9301 aaaaaagaag caaatgaagg agaaaatttc tccaagcttg ttcaagctta tggaaaaaat
     9361 aaaacattaa aggaaactga tggaaaaatg aattttgatt caaccaatcc agagattcct
     9421 actgaagtaa aaaaagcagc atttaaacta aaaaacgggg aagtttctga tatcattcct
     9481 gtaacagatc caacgactta tcagcaaagc tattatctag taaaaatggt aaaaaaacag
     9541 gataaaggtt ctaataaaga caaatacaaa tctgagctag aaaaaattgc taccgaagca
     9601 aaaactcttg atacggaatt catggataaa acaatccgta aagtgatgaa aaaagacaat
     9661 gtaactatta aagatcctta tgtaaaaaat atattcaaat aaacaaattt gacccaattg
     9721 gggatgtggc aaaatttgag aagtgatttt tggaaattcc ttcttatttt tgaggcaaac
     9781 cacttttgcc acaacttcat cggggccttt ttttatttgt accaaaacaa atcactggat
     9841 ttgttacaat catgaggata taatttaaaa aagtttttta tttctatcac atgaatcaat
     9901 gcgccattaa gtagattctt tcatgcttcc ctattttttc acttgccgta tcgcttcaaa
     9961 aacaactatc ataaactcaa actcgactga aaagttattt taaaaaagac taaaaatatc
    10021 ccttctggac ttgttcttct tattctgtta tactagagaa acacgaaaga tatttttatg
    10081 cgacactttt catttgtttt tatgaaattt attcaaaact ggcgtaactt cagagttaca
    10141 aggatgtatt agaggttagg gaatacatcg tttaaatgag aaataagtaa tagttagtaa
    10201 tagtcaccca aactttaaat taatgaatat tgaatcgtca gatagcctcc tcgagttttc
    10261 gagaaggcta tcgtttattt tatggagaaa ttgattcaga agtaatcagc gacctttttt
    10321 agttcaccaa tcgtttctgc ttggaaagtt tgcacccaat cttcttggaa gcccctcact
    10381 gctttatcaa tcgagggcat ctctaatact tgatctagta gctctttacc taacgttatc
    10441 gcatgagctc cagatcgaat ggctgtagtg acttgttcac aatttttgaa actagctgct
    10501 aatatttttg ttggtctttg cgtacgttcg atctcagtcc gcaacgaatc aatcactttc
    10561 atagcatcaa tgccttgatt ttgcatcctg ttataataag gtgcaatata atctgctcca
    10621 ttattaatag ctaaataccc ttgtaattct gtgtaaatag ctgtaccggt aatcaaataa
    10681 ccttcttttt tcaacttttt gatcgcttga aggcctgctt gattcaccgg caccttgata
    10741 aacgtatctt ttcccagttc ttctatgata actcgagcat cctctatcat ttcttcttcc
    10801 gttcttccta ttgtctgaat atggatagga atctgtccga ttattttttt gatttctttc
    10861 atatgcgaga agaagtttga cgctccttct tttttcagaa ttgtaggatt tgttgttacg
    10921 cctgttaaat tcaaaaactg ttgacaagaa taaatacttt ttgtatttgc tgtatcaagc
    10981 atgatttcca tatagctttc ccccattctg atcctcttga tcgattttaa tgattgtccc
    11041 ctttcttaaa tgcggcattt ccttatcttc tacatacatt gttcctggaa gttccggctc
    11101 atgagatcca tcaaatttta tcgtgatatg tcctaattca ttcaaattag tttggacaac
    11161 atctcctact gctgtgatta catacatttg tttatcaaaa cagagcttca tatcacaagt
    11221 tatttctttt cttacctgat tcaattcaat cttataacaa taatctgtta atgtttccgg
    11281 tgcttcatct ccaaataaaa tcattatttt ttctttcctg aatacttctg cttctatacc
    11341 aacatctgtt acaaccgttt caaagatcgt catctctgtt cctcctcgta aaatatcatt
    11401 tgtctaatag tttttattca aaatgtttct agattataaa atttattgaa taacacattc
    11461 ctaacggaat ttgtttcgat attgtgtgat ttctcagagt acaatggatg tatgga
//
LOCUS       DAFKHN010000076        11441 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFKHN010000076 DAFKHN010000000
VERSION     DAFKHN010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.076"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            185..1183
                     /locus_tag="LY912_002213"
     CDS             185..1183
                     /locus_tag="LY912_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBM6955871.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="LY912_002214"
     CDS             1295..1804
                     /locus_tag="LY912_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBM6955872.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="LY912_002215"
     CDS             complement(1834..2493)
                     /locus_tag="LY912_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBM6955873.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="LY912_002216"
     CDS             complement(2495..3259)
                     /locus_tag="LY912_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBM6955874.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="LY912_002217"
     CDS             complement(3267..3944)
                     /locus_tag="LY912_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBM6955875.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="LY912_002218"
     CDS             complement(3981..5366)
                     /locus_tag="LY912_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBM6955876.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="LY912_002219"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LY912_002219"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="LY912_002220"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="LY912_002220"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBM6955877.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="LY912_002221"
     CDS             6305..7162
                     /locus_tag="LY912_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955878.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDGTEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="LY912_002222"
     CDS             complement(7243..7578)
                     /locus_tag="LY912_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955879.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="LY912_002223"
     CDS             complement(7645..9015)
                     /locus_tag="LY912_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBM6955880.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="LY912_002224"
     CDS             complement(9093..9629)
                     /locus_tag="LY912_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6955881.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="LY912_002225"
     CDS             9938..11419
                     /locus_tag="LY912_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955882.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3516 a         2301 c         1855 g         3769 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatggtactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg accgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc t
//
LOCUS       DAFKHN010000077        11430 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFKHN010000077 DAFKHN010000000
VERSION     DAFKHN010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.077"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..937
                     /locus_tag="LY912_002226"
     CDS             <1..937
                     /locus_tag="LY912_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBM6955883.1"
                     /translation="FLIVFGGYLGWLLIETQNIFIGGLLALIGIPILILLAIGIYILI
                     IFLFWNGVVVMKKESRSLANLLTLLLGVALTIFLILDYTLVHWLPQWANALFAVIPFI
                     FAYLLIVFFNFMTVSILYQFNRPRYNQDYIVVLGAGLIDGERVSPLLAKRINKAIAFY
                     WAQSKATLNPPVLLMSGGKGTDEKVAEAIAMKQYALEKGIPERDILVETNSTTTLENM
                     LFSKEIMDQQMNGPYRAIFTSNNYHIFRAGLYARQAKLNANGIGAKTALYYLPNAILR
                     EFIAILVLHKKRHLIICGLMIGFAVFSALILKFAQ"
     gene            complement(1114..2382)
                     /locus_tag="LY912_002227"
     CDS             complement(1114..2382)
                     /locus_tag="LY912_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBM6955884.1"
                     /translation="MENRLPDPLKVIIYMIKWLLITAILGIFMGSLSAFFLTSLTDVT
                     AIRLEHPWLLFLLPISGGLFAYLYTTYGGNSSRGNNLVIDQGNGGNEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALAENFARWLKLNKIEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEALFPSFFAALFANFVTESFNVKHTHYQMGAIPAWDPS
                     LFFKLLLAGIAFGIIGWLFSRSIVWLKAWYAKRIPHPVLRNFIGGAVVVLVVVILQTQ
                     RYLGLSLPLLQDAFNGSAHPYDFLGKLGFTVLSLGAGYQGGEVTPLFEIGATLGATLA
                     PILHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGGQAASYFFMICLISFMCSGN
                     SGIYSAQKVEVKKGILFLPILGRISRQKEK"
     gene            complement(2543..3190)
                     /locus_tag="LY912_002228"
     CDS             complement(2543..3190)
                     /locus_tag="LY912_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBM6955885.1"
                     /translation="MEKTIKPYQYYFIKREVEQLLSAYSSVNDPKTVQTVQALAAEKI
                     HEVLGHPNTAVNEFMEKVLDVTLKKEKAERLLEELKVIVLPFIQPTKPQIDKLFRKVK
                     KLKQPDWNQLDLREHTYIGWNDPGSQKKFMIYYEEEKLKGISGTLSPTINKGICSICQ
                     RTSNVSLFLSTTKTGSDGTYTKKGNYICHDSDQCNQQLVQLAPFYEFTERVKRER"
     gene            complement(3455..3958)
                     /locus_tag="LY912_002229"
     CDS             complement(3455..3958)
                     /locus_tag="LY912_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBM6955886.1"
                     /translation="MTEKWREDEEYMSYINDLLETDAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYKLAKKWGGDARATARAGLLHDLFYYDWRTTKFDEGTHAYVHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMTASMKQKWQRY
                     FGKEQSI"
     gene            complement(4082..4846)
                     /locus_tag="LY912_002230"
     CDS             complement(4082..4846)
                     /locus_tag="LY912_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBM6955887.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKGEYLLEGFHLIEEAVAS
                     NAKVNELFITQRGLTEWASWLEENQALSVTLVSEEVMATVSDLPTPQGIMAVVEAEKR
                     EIPNFEGGWLLLDNVQDPGNVGTMIRTADAFGLSCVVLGKGTADVYSTKVLRSMQGSN
                     YHLPIIQEDLTKLLPILKEQGFITYGTELNEEAVSLNDIQTTENYAIVMGNEGQGVRP
                     EVLALTDKNVYIPIQGNAESLNVGVAAGIMLYHFSV"
     gene            4954..5229
                     /locus_tag="LY912_002231"
     CDS             4954..5229
                     /locus_tag="LY912_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBM6955888.1"
                     /translation="MNKIKMNVQGRVQSVGFRYMTKIVADQLGITGTVKNEDDGSVTI
                     EAAGDDEAIKKFVEEVKRSPSPSGRVQYVDLQENPMMEDRKKFVVIG"
     gene            complement(5577..6728)
                     /locus_tag="LY912_002232"
     CDS             complement(5577..6728)
                     /locus_tag="LY912_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBM6955889.1"
                     /translation="MDKSKIARRFQQPAENLLMNIAILAKEKEDIIDLSIGDPDLITD
                     PTIIEAAYTDVKNGATNYTAPDGSKEFLSTVVDFYQKKYGLSVECNQVRATVGAMHGM
                     YLVLQALLDPEDEVIIHEPYFSPYREQVILSGGKPVFVPTYEEKGFQLDVEDLKAAIT
                     DRTKVIVINSPNNPTGAVFSESTLKKIAEVAIENELYIISDEIYEDFAFKEKFVPMAR
                     FAPDNTITVSGVSKGFAMTGWRLGYMIAPAYINQIAGLINENITYSAPTASQRGAIYA
                     LKHYEQLVPPVVEVFKERLAYIEKRVAEIPYLSLSSVSGSMYAFINISKSGLDSVTFV
                     EEVLEKSGVLFVPGKAFGETIGDNYIRLAATQPLEILGEAFDRLAKLNF"
     gene            complement(6748..7470)
                     /locus_tag="LY912_002233"
     CDS             complement(6748..7470)
                     /locus_tag="LY912_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBM6955890.1"
                     /translation="MLNVKKLSKSFGENEVLKSIDLSVKEGEVVVIIGPSGSGKSTIL
                     RCMNLLEEPTSGEIFFKGQNITAPDSDINQIRQKMGMVFQSFNLFPHMNVLENLTITP
                     VKIKKEDPKKAKEHALSLLNQVGLKEKVDSYPTSLSGGQQQRVAIARALAMNPDVMLF
                     DEPTSALDPEMVGEVLAVMQDLAKKGMTMVVVTHEMGFAKEVADRVIFMADGIIQEEG
                     TPKEIFENPQNSRTQDFLNKVL"
     gene            complement(7463..8914)
                     /locus_tag="LY912_002234"
     CDS             complement(7463..8914)
                     /locus_tag="LY912_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBM6955891.1"
                     /translation="MKKGINILLVALMFLLVFLPVKVQGAEKDEIYERIKQSGELVVG
                     LSADYAPYEFHANVDGKDKIVGFDVSIAEKIAKDMGVKLKVEELGFDALLGALKTGKI
                     DLVISGMAVTEERLQEVDFSDPYFVVQQKVLVRKEDKNKFKTTADFSGLAVGAQKQTT
                     QEELVKNELTGAELTSLQKVPDLINNLLNEKVEGVVLEQPVAEAYAQQNKKVALTPVK
                     FAQGEKTTAIAMSKNTPELKNHVNASIKTINDDGLLKDYQKQANQLMFQDDQSFLQKY
                     GPYYLIGTKYTILLAFVGVLFGMVFGSLLALMKLGKNKFLKALAIIYIEYVRGTPLLV
                     QIFIVYFGTGVLGLDLSKLVAGCIAVSLNSAAYVAEIVRAGINAVNKGQMEAARSLGM
                     DQKEAMRFIIFPQAIKNILPALGNEFVTIIKESSVVSVIGVSELIFQTGVVQGASFKP
                     FLPYVLVSLIYFVLTFSISRILALVERRMGLNA"
     gene            9056..10138
                     /locus_tag="LY912_002235"
     CDS             9056..10138
                     /locus_tag="LY912_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBM6955892.1"
                     /translation="MTKNLIVRGAPQEYEIKENAWDSLPEHLYKRHIDNVLILHGKTS
                     WKAVKDVFPDLSITKIFEYYGGECTDPLADSFVSLCKKKDFNGIIAVGGGKVADLGKL
                     IAYKTNLPIIILPTLAATCAAYTPLSVVYNEEGVMLRYDMFPKANDLVLIDPKIILHS
                     PREMMIAGIGDTLAKWYESHAIISQLTIKPIEVQVAEFAALRCREILLEKSAEAMEAM
                     DQQKINQAFIDVVETNILLAGMVGGFGDDYGRTAGAHSIHDAMTVLPDSHQQLHGNKV
                     AYGILVQLMIENKLAEIEHLLPFYHHLNLPTSLADMGLHLTESDYQAVAERACLPDEM
                     IHFMKETITPALVVQKMKELEQVTQG"
     gene            10472..11410
                     /gene="yidC"
                     /locus_tag="LY912_002236"
     CDS             10472..11410
                     /gene="yidC"
                     /locus_tag="LY912_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBM6955893.1"
                     /translation="MNKWKNWLLGSGLVTIMLFLSGCVRMDSNGNPDTSGIIYRILVH
                     PMGQAITYLVENFNWSYGWAVILMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     ATQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESTFYGIDLGNPSLVLVAIAGIAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGIFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTPAEPAKQTKKQVQAPKNNAKNGRNAGKQQKRK"
BASE COUNT         3415 a         2411 c         2060 g         3544 t
ORIGIN      
        1 gtttttgatt gtctttggtg gttatctagg gtggctacta atagagacgc aaaatatctt
       61 tatcggtggg ttattggctt tgatcgggat accaatatta attcttttgg caatcggtat
      121 ctacattttg atcatttttt tattttggaa tggtgttgta gtcatgaaaa aagaatcccg
      181 ttctttggcc aaccttttga ctctcttgtt aggagtcgct ttgactatct ttttgatatt
      241 ggactataca ttagtccatt ggctcccaca atgggcaaat gctctatttg ctgtcattcc
      301 gtttattttt gcttatctac tcatcgtttt ctttaatttt atgactgttt caattttgta
      361 tcagttcaac cgtccaaggt ataaccaaga ttatatcgtt gttctcggcg ctggcttgat
      421 tgatggtgaa cgcgtatctc ccctacttgc taaaaggatc aataaggcga tcgcatttta
      481 ttgggcacaa agtaaagcaa ctttgaatcc gccagtcttg ctcatgtcag gaggaaaagg
      541 aaccgatgaa aaagtagctg aagccattgc aatgaaacaa tatgctttag aaaaagggat
      601 tcccgagcgt gatattttag tagaaacgaa ttccacaacg acgctagaaa atatgctgtt
      661 ttcaaaagaa ataatggatc agcaaatgaa tgggccttat cgcgcgattt ttacttcaaa
      721 taattaccat atctttagag ctggactata tgcgcgacaa gcgaaactca atgcaaacgg
      781 aatcggtgca aaaactgcac tatactactt accgaatgct atcttaagag aatttattgc
      841 catccttgtc ttacacaaaa aacgccatct tatcatctgt ggcttaatga ttggctttgc
      901 agtattttct gctcttattc tcaaatttgc tcaataaaaa agagcgtggg acaaaactaa
      961 aaatcagttt tgccacagac tctaactccg aataaacggt gggagcagaa gcaactcctt
     1021 cggaaataag cgaaattcac aaaaatttaa aaagcaattt tcgtgaattt cttcttattt
     1081 ctcggagtta aacacttctg tcccaacctc tttttatttc tctttttgtc gtgagattct
     1141 tccaaggatc ggtaggaaca agattccttt tttcacttca actttttgcg cagaatagat
     1201 tccactattt cctgaacaca taaagctaat caaacagatc ataaagaagt agctggctgc
     1261 ttgacctcca aaaagttcga tccccataac aaagcaagca atcggtgtat tcgttgctcc
     1321 agagaacacc ccaataaacc ctaatcctgc taaaaaaggt actgatacat gaagaatggg
     1381 tgctaatgtc gcacctaaag ttgccccaat ctcaaacaaa ggggtcactt cgcctccttg
     1441 gtatcccgcg ccaagtgata gaacggtaaa gccaagtttc ccaagaaaat cataaggatg
     1501 agcacttcca ttaaatgcat cttgtaataa aggtaagctt aatccgagat atctttgcgt
     1561 ctgtaaaatc actactacga gtaccacgac tgctcctcca ataaagttgc gtaaaactgg
     1621 atgggggatc cgctttgcat accaagcttt taaccagacg atcgaacggc taaagagcca
     1681 gccaatgata ccaaatgcaa tgcccgcaag caacaatttg aagaaaagtg aagggtccca
     1741 tgcaggaatc gcccccattt gataatgggt atgcttgaca ttgaaacttt ccgttacaaa
     1801 gttcgcaaaa agtgctgcaa aaaagcttgg aaacagtgct tcggttctca cttttccgat
     1861 tgccaatact tctaatccaa acaatgtccc agccaagggt gtcccaaata ctgagctaaa
     1921 acctgcgctg atcccactga tgacaagaat ctcacgctcg attttgttca attttagcca
     1981 acgagcaaaa ttctcagcaa gtgccccgcc catttggacc gctgtaccct cccgaccaac
     2041 agaaccacca aaaagatgcg tggtaatggt gccaaataag gtcagtggga tcagccgtaa
     2101 tggaatcttt tcatttcctc cattcccttg atcgatcact aaattgtttc cccgggaaga
     2161 attgccccca tacgtcgtat atagataagc aaaaagtccc ccacttatcg gcaaaagaaa
     2221 aagtaaccaa ggatgctcca gccgaatagc tgtcacatca gtcaaactag ttagaaagaa
     2281 tgcggataaa cttcccataa aaatacctaa aattgctgtg atcaataacc atttgatcat
     2341 atagatgatc accttcaatg gatcaggtaa tcgattttcc atctcatttc ctcctcaaaa
     2401 aaacgcctac taaaaaaagg ggtagccccg tttctttagt aggcgtcatt agttatctta
     2461 cgatcaacgt ttaaaggcga acaccatcac ctattcactt caccaaataa gatagcatat
     2521 ttttcagaaa aatacaatga aatcaccgct cacgtttcac tcgttctgtg aattcgtaaa
     2581 aaggagctaa ttgtaccaac tgctgattac attggtcact atcatgacaa atataatttc
     2641 cttttttcgt gtatgttcca tctgaaccag tttttgtggt agaaagaaag agtgaaacat
     2701 ttgaagttct ttgacaaatc gaacaaattc ctttgttgat tgtaggagat aatgttccac
     2761 tgatcccttt tagtttttct tcttcataat agatcataaa ttttttttgg ctacctggat
     2821 cattccaacc aatataagta tgttccctta aatccagttg attccaatct ggttgtttta
     2881 actttttcac ttttcggaat aatttatcga tctgcggttt tgtcggttgt atgaatggaa
     2941 gaacgatcac tttcaattcc tctaatagtc gttctgcttt ttcttttttt agagtgacgt
     3001 ctagtacctt ttccataaat tcatttacag ctgtattagg atgaccaagt acctcgtgga
     3061 tcttttccgc agctaatgct tggactgttt ggactgtctt tggatcattc actgaactat
     3121 aggcgcttaa cagctgctcg acttctcgct tgataaaata atattgatat ggtttgattg
     3181 ttttttccat gactttgagt cctttcttct ttcaaaatcg gctactttga agaaaaaagt
     3241 gatctttcta tcaaagtgcc tttagataaa gccctcaaac tcttttaaat aagatacaca
     3301 tcgcatctta tcatcacccc ctttattttt atgttggtta tgtacttttt catctcaaca
     3361 aagtaaacac taaaaagacc aattagtcaa tgtctaaaca aaaaacccga ggattttttt
     3421 caaaatactc gggtcaaata cttagttaac taccttaaat cgattgttct ttaccgaaat
     3481 atcgttgcca tttttgtttc attgaagctg tcattggttg agctgcttct ttgactgcac
     3541 aatatttatc cacaaaagta acgatataac cttctttata tttaggaggg gcaatcgttg
     3601 ctccccacat atgtttcaaa ataatatcac gctctagatc tgaaagctcc gtgatttttt
     3661 cagcattttt cacagcgatc cttgggtgaa catacgcatg tgtaccttca tcgaacttcg
     3721 tcgtacgcca atcgtagtaa aataaatcat gtaaaaggcc tgctcgagca gtcgctcttg
     3781 catcaccgcc ccattttttc gctaatttgt agctatagta agacacactg attgaatgct
     3841 ctaatcgtgt cgagtggaca tgttgcgtgt aatttgctaa tttctttact gcatcagttt
     3901 ctaatagatc atttatataa gacatatatt cttcgtcttc acgccatttt tctgtcataa
     3961 ttatcgatct gccacctttt tgaattccat ttatctttga aattgaactt agtataccac
     4021 tagtgttcgt aatattctag tgaggttttc gcaaaatgca gaaagcttaa tagttcctta
     4081 actatacgga gaagtgataa agcatgatgc ccgctgcaac tcctacattt aaagactccg
     4141 catttccttg aatcggtata tacacatttt tatccgttag cgccagcact tctggacgta
     4201 cgccttgacc ttcattcccc atcacgatcg cataattttc tgttgtctgg atatcattca
     4261 gggacactgc ttcttcattc agttctgttc cataggttat aaatccttgc tctttaagga
     4321 taggcaatag ttttgttaga tcctcttgga tgatcggtaa atgatagtta ctcccctgca
     4381 tgcttcttaa tactttggta ctgtagacat ccgccgttcc cttacctagt acaacacaag
     4441 atagaccaaa agcatcggct gtgcggatca ttgtccctac attgccggga tcttgtacgt
     4501 tgtcgagcaa caaccaacca ccttcaaaat tcggtatctc tcttttttca gcttccacca
     4561 ctgccatgat cccttgcgga gttggtagat ctgaaacagt tgccatcact tcttctgata
     4621 ctagtgtaac agaaagcgcc tgattttctt caagccaact agcccactca gtcagaccgc
     4681 gttgcgtaat aaaaagttcg ttgaccttcg catttgaggc aacagcctcc tcgatcaggt
     4741 gaaacccttc aagcagatat tccccttttt cttcacgata ttttttctta tgtaattttt
     4801 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattt ttcacctcaa
     4861 ctgattatac catggattag atcattgcac ttgttcagta gcaaaaaagt cggtatcatt
     4921 aatttaaaaa taaaagaaag aacggtgaat aaaatgaaca aaatcaagat gaacgtgcaa
     4981 ggacgtgtac aaagcgttgg ttttcgctat atgacaaaaa tcgtagcgga tcaattaggg
     5041 atcaccggaa cagtgaaaaa tgaagatgac ggctctgtca cgatcgaagc tgcgggcgac
     5101 gatgaggcaa tcaaaaaatt cgtggaagaa gtcaaacgat caccaagccc cagcggacgt
     5161 gtccaatatg tagaccttca ggaaaatccg atgatggagg acagaaaaaa gtttgttgta
     5221 ataggctgac cttctagaaa tgaataggaa atgtcagaaa aatcggactg tctgtatgta
     5281 gatcgaaaaa gtttgcccct ctctccatcc tagatcgaca aaaaaacatt cttattagcg
     5341 agtttagtaa ccagtgatag gcatacgtaa aagcgggagg acttcaaaaa ttttggttca
     5401 ataaaatgga gtctataata ttttatggta gtggaaaatc gactttgatt ttccactacc
     5461 actttttcat tgtcaaatcc tgacgctgcc cagtcaacaa gccaactctc gaaaggatca
     5521 ttttccctct ttgttctaat ggatacccat agctgttttc aaatatacag ttttatctaa
     5581 aaatttagtt ttgctaaacg atcaaaggct tcacctaaga tttccaatgg ctgagtcgct
     5641 gctagtcgaa tatagttgtc cccgatcgtt tccccaaacg cttttccagg gacaaaaagt
     5701 acgccgcttt tttctaaaac ctcttccaca aacgttactg aatcgagccc actcttactg
     5761 atattaataa aagcatacat gcttccagaa acagaagata aagataagta agggatttct
     5821 gccactcttt tctcaatata agctaatcgt tctttgaata cttcaacaac tggcggtaca
     5881 agctgttcat agtgctttaa ggcgtagatt gcacctcttt gagaagcagt cggtgcggaa
     5941 taagtgatgt tttcattgat caacccagca atttgattga tgtatgctgg tgcgatcatg
     6001 taccctaagc gccagccagt catcgcaaac cccttcgata caccactgac agtgatcgta
     6061 ttatcgggcg caaatcgcgc catcggtacg aacttctctt taaaggcaaa gtcttcataa
     6121 atctcatcgg aaatgatata gagttcattt tcgattgcga cttcagcgat ttttttcaac
     6181 gtgctttcag aaaaaacagc tcccgtagga ttattcggcg aattgatgac gatcaccttt
     6241 gtacgatccg taatcgctgc ttttaaatct tccacatcca actggaagcc cttttcttca
     6301 taggtaggaa caaaaacagg cttgcctcca gataaaatga cttgttcccg atatggtgaa
     6361 aaataaggtt catggatgat gacctcatcc tctggatcta gtaatgcctg taaaactaga
     6421 tacatcccgt gcattgctcc gactgtagct cgaacttggt tgcattcaac gctcaatcca
     6481 tatttctttt gataaaaatc tacgaccgtt gacaagaatt ctttgctgcc atcaggcgca
     6541 gtataattag tagcaccatt ttttacatct gtataagctg cttcaataat cgtcggatca
     6601 gtgatcaagt caggatcacc aatcgataaa tcgataatat cctctttttc ctttgccaaa
     6661 atagcaatat tcatcaacag attttctgct ggttgctgaa accggcgtgc aatcttactt
     6721 ttgtccatct tacttcctcc atctttgtta caacactttg ttcaagaaat cctgtgttcg
     6781 actattttgc ggattttcaa aaatctcttt cggtgttccc tcttcttgaa tgatgccgtc
     6841 agccataaaa atcacacgat cggcaacttc tttagcaaaa cccatttcat gagtgaccac
     6901 gaccatcgtc atcccttttt tagctaaatc ctgcatgact gccaacactt caccgaccat
     6961 ttcaggatca agtgcagatg taggttcatc gaaaagcatc acatcaggat tcattgctaa
     7021 tgctcgagca attgctaccc gttgttgctg tcccccagat aaactggtag gataactgtc
     7081 cactttttcc tttagaccaa cttggttcaa taatgataga gcatgttctt ttgctttttt
     7141 agggtcttct tttttgattt ttacaggtgt gatggtcaaa ttttcgagta cattcatatg
     7201 gggaaacaaa ttaaaacttt gaaataccat tcccattttt tgacgaattt gattgatatc
     7261 gctgtcaggg gctgtaatgt tttgtccctt aaaaaagatt tcaccagaag ttggttcttc
     7321 cagcagattc atacaacgta gaattgtact tttcccactt cctgaagggc caatgatcac
     7381 cactacttct ccttctttca cagaaagatc aattgatttt aagacttcat tctcgccaaa
     7441 actttttgac agttttttta cattaagcat tcagacccat tctcctttca actaaagcta
     7501 atatacggga aatactgaag gtcaacacga aataaatcaa agagaccaac acatatggta
     7561 ggaatggttt gaagctagca ccttgtacca cgcccgtttg aaagatcaat tccgataccc
     7621 caatgaccga aacaactgag gactctttga tgatcgtgac aaactcattt cctagagctg
     7681 gaagaatatt tttgattgct tgtgggaaga tgatgaaacg catggcttct ttctggtcca
     7741 ttcctaaaga acgtgcagct tccatctgtc ctttgttgac cgcattgatc ccggcacgga
     7801 caatttcggc tacataagca gcactattca acgagacagc aatacaacct gctaccagtt
     7861 tcgatagatc caatcccagt actcctgttc cgaagtaaac gataaagatt tgaactaaga
     7921 gaggtgttcc ccgtacgtat tcgatataaa taatggctaa tgcctttaaa aatttattct
     7981 tacccaattt catcagtgca agcaaactac caaagaccat tccaaacaat acacccacaa
     8041 aagctaataa aatagtgtat tttgttccaa tcaaataata cggaccgtat ttttgaagaa
     8101 aggactgatc atcttggaac atcaattgat tcgcttgttt ttgataatct ttcagcaagc
     8161 cgtcgtcatt gatcgttttg attgacgcat tgacatgatt tttcagttct ggtgtatttt
     8221 ttgacatcgc aatagctgtg gttttttcgc cttgcgcaaa ttttactgga gtcaaagcta
     8281 ctttcttatt ctgttgggca tatgcttctg caactggttg ttccagcaca acaccttcaa
     8341 ctttttcatt cagcaaatta ttgatcagat caggaacttt ttgcagggag gtcaactctg
     8401 caccagtcag ttcatttttc actaactcct cttgtgtggt ttgcttttgc gccccaacgg
     8461 ctaagccaga aaagtcggct gtcgtcttaa atttattttt gtcctcttta cgaacgagta
     8521 ctttttgctg taccacgaaa tatgggtcag aaaagtcaac ttcttgtaaa cgttcttcag
     8581 tcaccgccat accagatata actaaatcga tcttgccagt tttcaacgca cctaataatg
     8641 catcaaaacc aagttcttct acttttagtt tcacacccat atcctttgcg atcttttcgg
     8701 caatggatac atcaaaacca acgattttat ccttaccatc cacattcgca tggaattcat
     8761 agggcgcata gtctgcagat aggccaacga ctaattctcc actttgtttt atccgctcgt
     8821 aaatttcatc tttttctgca ccttgtactt ttactggtaa aaaaaccagt agaaacatca
     8881 gcgccactaa taatatgttt attccttttt tcatccattt ggccaccttt gaataataat
     8941 gtaatcagaa aagctataaa agaataaata ttcataaata acttgctaat atactagcat
     9001 aactattata ataaaaaaag attaatttaa aaaaataatg gaagaagttt tttatatgac
     9061 aaaaaattta attgttcgcg gtgcccctca agagtatgaa ataaaagaaa acgcatggga
     9121 ttcactccct gaacaccttt acaaaaggca tattgacaac gttttgattc tccatggaaa
     9181 aacatcttgg aaagcagtaa aagatgtttt tccagattta tcaataacaa aaatttttga
     9241 atattatggt ggagaatgta ccgatccact tgctgacagt tttgtttctt tatgcaaaaa
     9301 gaaggatttc aatggtatta ttgcagtcgg cggcgggaaa gtagcagatc taggaaaatt
     9361 gattgcctat aagacaaact taccaatcat catcttacct accttagctg cgacgtgcgc
     9421 agcttatact ccacttagtg tggtctataa tgaagaagga gtgatgcttc gctatgatat
     9481 gttccctaaa gcaaatgatt tagtgttgat cgatccaaag atcattttgc actcccctcg
     9541 cgagatgatg attgccggta ttggtgacac cttagcaaaa tggtatgaat ctcacgcaat
     9601 catctctcag ttaactatca agcctatcga agtccaagta gcggaatttg cagcgttacg
     9661 atgccgcgaa atccttttag agaaaagtgc agaggcaatg gaagcgatgg accagcaaaa
     9721 aatcaatcaa gcttttatcg atgtcgtgga aacaaacatt ttattggctg gtatggttgg
     9781 tgggtttggc gatgactacg gccgaacagc tggagctcat tccattcacg atgcgatgac
     9841 cgtactccct gatagccatc agcaacttca tggaaacaaa gttgcatacg gtatccttgt
     9901 ccagctgatg atcgaaaata aattagcaga aatcgaacac ctactgccgt tttatcatca
     9961 cttgaactta ccaacgagtt tagctgatat gggtttacat ttaacagaaa gtgactatca
    10021 agccgtagct gaacgtgcat gtttacctga tgaaatgatc cacttcatga aagaaacgat
    10081 cacaccagca ctggttgtcc agaaaatgaa agagttagaa caagtgacac agggatagtt
    10141 agccccttat accatggcag tcagcttttt tatggatcgg ctcaatggta aaaaaaaaga
    10201 agtggaaaaa attgacattc cacttctttt ttttgcgcta aaattatgat ttcaaggaaa
    10261 tatccgttgc tcatcttatt ttagagaacg gaggtgctaa gtatgcttta tactgaagta
    10321 tttttagctg gattcttctt tttaacatta agcgtctttt ttgatcctcc aatcggttat
    10381 ttctatgaaa tttctatgaa gttgattgaa ttatgagcgc ttttttagta tagttaagct
    10441 tgtgtaaaaa ttataaaaga ggaagtattt tatgaataaa tggaaaaatt ggttattggg
    10501 ctctgggctt gtcacgatca tgcttttctt gtccggttgt gtccgcatgg attcaaatgg
    10561 taaccctgac acttcaggaa tcatttaccg tatattggtt cacccaatgg gacaagcgat
    10621 tacatattta gtggaaaact ttaattggtc ctacggctgg gctgttatct tgatgacagt
    10681 catcgttcgt atcatcattt tgccattagg tattagtcaa tcgaaaaaaa caatgatcca
    10741 atctgaaaag atgcaagcat tgaaaccaca agttgaagct acgcaacaaa aattgaaagc
    10801 tgcgacaact cgagaagaac aaatggctgc acaagctgaa atgcaacaag tttatcgtga
    10861 aaatggctta agtatgactg gtggtatcgg ttgtttaccg cttctgatcc aaatgccgat
    10921 cttttctgcg ctatatttca ctgctcgcta tacagaaggc atccgtgaat caacctttta
    10981 cgggatcgac ctaggtaacc ctagcttagt tttagtagcg attgccggta ttgcttattt
    11041 acttcaaggc tatatctcaa ctatcggtat ccctgaagaa caaaagaaaa cgatgcgtac
    11101 gatgttgatc gtatcacccg ctatgatcgt cttcatgtcg atcagtgccc cagctggtgt
    11161 cactctttac tgggtagtcg gtgggatctt tagttgtcta caaacattca ttacgaatgt
    11221 catcatgaaa ccaagattaa aagcgcaagt tgcggaagaa ttaaaacaaa atccgccaaa
    11281 acaagtggtg acgcctcgta aagatgtcac acctgctgaa cctgcgaagc aaacaaaaaa
    11341 acaagtacaa gcaccaaaaa acaatgcgaa gaatggtcgg aatgctggta aacagcaaaa
    11401 gcgtaaatag ttatttgtaa ctagcttctt
//
LOCUS       DAFKHN010000078        11369 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFKHN010000078 DAFKHN010000000
VERSION     DAFKHN010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.078"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..304)
                     /locus_tag="LY912_002237"
     CDS             complement(<1..304)
                     /locus_tag="LY912_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955894.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPY"
     gene            complement(350..712)
                     /locus_tag="LY912_002238"
     CDS             complement(350..712)
                     /locus_tag="LY912_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBM6955895.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADEVKKSTEQTFS
                     EMKEQIVHGQETGKLYLIIGWVSMVVSLAFIPVVFGAVAVIMGYLYRETDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(749..964)
                     /locus_tag="LY912_002239"
     CDS             complement(749..964)
                     /locus_tag="LY912_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955896.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            1091..1426
                     /locus_tag="LY912_002240"
     CDS             1091..1426
                     /locus_tag="LY912_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955897.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(1502..3499)
                     /locus_tag="LY912_002241"
     CDS             complement(1502..3499)
                     /locus_tag="LY912_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955898.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(3597..3872)
                     /locus_tag="LY912_002242"
     CDS             complement(3597..3872)
                     /locus_tag="LY912_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955899.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMEQYKG"
     gene            4107..4841
                     /locus_tag="LY912_002243"
     CDS             4107..4841
                     /locus_tag="LY912_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6955900.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIIEEFDNNILLLTSSIEEQLEEMIDEGIHSQVEDMNYPEEAVNEIIDN
                     INKLKQTISSIGKKYTKKKMKGGDTI"
     gene            4880..6022
                     /locus_tag="LY912_002244"
     CDS             4880..6022
                     /locus_tag="LY912_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBM6955901.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(6117..7508)
                     /gene="sufB"
                     /locus_tag="LY912_002245"
     CDS             complement(6117..7508)
                     /gene="sufB"
                     /locus_tag="LY912_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBM6955902.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(7513..7983)
                     /locus_tag="LY912_002246"
     CDS             complement(7513..7983)
                     /locus_tag="LY912_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBM6955903.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(7970..9205)
                     /locus_tag="LY912_002247"
     CDS             complement(7970..9205)
                     /locus_tag="LY912_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBM6955904.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAH
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     SFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVINPVQELAELVHENGGVIVVDGAQSAPHMTIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQELGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VIAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFKHGTI"
     gene            complement(9202..10488)
                     /gene="sufD"
                     /locus_tag="LY912_002248"
     CDS             complement(9202..10488)
                     /gene="sufD"
                     /locus_tag="LY912_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBM6955905.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(10501..11274)
                     /gene="sufC"
                     /locus_tag="LY912_002249"
     CDS             complement(10501..11274)
                     /gene="sufC"
                     /locus_tag="LY912_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBM6955906.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
BASE COUNT         3365 a         2316 c         1934 g         3754 t
ORIGIN      
        1 tatatggtat ctctacatat acacggtctt tctttggata gtactcgaca tttatattga
       61 tagcacttcc attgtctaac gtagctttag cccggtatgt gttatctcca ttttcatgag
      121 taatcgtcac atcatcacat gacctattta agttgtactg ttcttgtaaa atctgtgtca
      181 ccaatggttt agatgacttc tctaatccag atgtacctgt catttttgaa aaaatgatac
      241 ctataatagc caagacaacg atacctataa tgacaaactt cttgttcata tttactttat
      301 tcaacttttt atctcctatc tccaaaataa tttgctctta tccctcttat cagtacattg
      361 acatccctaa aagtacacca aagattgctc cagctacccc tgctatcatc aaaatcgtac
      421 ccattttctc atctgtttct cgatataagt agcccataat aacagcaaca gcaccaaata
      481 caacaggaat aaatgctaac gatactacca tagaaaccca accaataatc aaatacagct
      541 tccctgtctc ttgtccatgt acgatttgtt ccttcatttc actaaatgtc tgctcagtac
      601 ttttctttac ttcgtctgct ccagttgtct catctgtttc ttgtaatgct ccgcaaaact
      661 ggcaatactt actttcatct gttatttctt taccacattt tctacaatac atgtcttctc
      721 ctcctaaaat cattcaattg cttaatagtt aactgtttac tttattaaac acatcagaaa
      781 acagctcgtt tattggtaca cttaatatct cagaaagcat tttcatttga tagggtttag
      841 gaatcgttct ccctgtttgc cacgaactta cacattgctg tgtaacattc atttttttgg
      901 ctaactccgt ttgagaaagt cctttttctt ttctgtatcg gctgagatta cttacttttt
      961 tcatgattct cccctcctgt tttattatat acaacaatat gatgtatttc aactcataaa
     1021 atataaaaaa cttcaaatac cattacaaat acaacaactt gttgtactat actgagatgg
     1081 gggtgtatta atgaaacaga aacaatatgc gaaggtcatt agagaaaagc gaaaagctct
     1141 cgggtggaca caaaaagaat tagctgaaaa aatcttctct acacaacagg cagtagcaag
     1201 atgggaaaat tctgtaacag agcctaacct cgatagctta acagctcttt ctagagccct
     1261 aggaacccct gtaagccatt ttctagacaa tgttgtcgta gattatgagg aagagttttt
     1321 ggctctctat cgttctctta gcactgaaga tgcagttcga acaattgact atatgaagct
     1381 attaaaaagg caagaaaatg aacgcaatca gctattgaaa gattgaaaaa taaataaccc
     1441 accgaacttt aacggtgggt gtattgagat gaaataagat taagagctat ggataacctg
     1501 tctagtttaa tacaattggg tcttttctct tccttactct ccgtccatca tctcttgtta
     1561 cacttgtaaa ttgatacaga ggaactatcc cagctcctga taatatcaat tcttttattg
     1621 tttcatctat ccctgcccct ttcgctaaat atattaaaaa actactactt gctttcacat
     1681 tgtatagttt cttaatatcc ttagaagctc gttcaagagt gaatccttgt ttaacaaagt
     1741 agcctctgtt ttttattaaa gcatttttca cgctgttatc cccaacatta cgtaggcgtt
     1801 cacaaacagt gttaataagt tctttctctg tcattagata tgtcccttgc cacgataagc
     1861 cctgtaaaac ttcatgtgct tcatctaaaa tcaattgttt ttccttgctg agttctgatc
     1921 gggaattttg aggaaatact cttttagcct ctttttcgtt aaaacatatc ttaacccatt
     1981 cataagaaaa atattgatat gtaaaatgaa ttttttccag aagtggaagg atatcttcat
     2041 tcaatttttg aatcacagaa gttgcattaa aaacgtctaa tcgatagaca ttgcttctct
     2101 tatgattaaa gtttcctaac gctttctctt cctttaacct atttaggtat tcgagcatct
     2161 tcaaaggaac atcttcatca tctaattttt ttatcaatcc tataaaagtc ataagtgata
     2221 gtaacttatt acatttatct atgtcataag ttttaccata gtaagaactc atttttttag
     2281 ctaattgttc ccccgacaaa atacaagtca cactttcctt actatcatca aaaaaattaa
     2341 catcagaaag caagacatca tagacacgtc gcatttcctc tagataattc cttattgtcc
     2401 tgaaaagttt gtctttcatt gattcaagag tgtcaaaaag tacttttgat tcctctttca
     2461 attttcgaaa atgtgtagga tacaagtcta ggttctctaa tagccaatta aatgtttcta
     2521 cccgactgtc tttctttaaa attagcatca caactccaat aaaattttca ctgatatcac
     2581 aattactgga atgacaataa aaaatggaat gcccagtttt actggtaaaa atactagcag
     2641 agggattatg atcgttgtga aacagacatc ttaagttttt acttgactta agtaatttat
     2701 tcatatcaat ggttaacaat ctttcataaa tctcattaaa agacatgtcg gaggaatcaa
     2761 acaggcagtc tttaaaccac tgtttcattt cttctttgtc gtcatttttt atcaacttaa
     2821 caaaatcggt ttcattgact agttcatact ctctccctga atcactttga caatttttag
     2881 aacatgtcat ggtaaaatca atcggaagct cagtaatatc taacatgttg tcttcattaa
     2941 ttattatcac tgcatctgac ttatatcctc caaaaaacat tctattcgaa gcatttacat
     3001 tgtcatcaca cccggggatg ttctttttca agtattcgta aacagcaacc attttaccat
     3061 agtcagtaat tgcttctttt aatagaaaga caatcttgta tttttctaga ttttcagagt
     3121 accgaatact tttttgtatc gcaaacgcag aattatgaac taaattgata gataaaacct
     3181 tttctacgct taagtatcta ctatcatctt tactcaaatc tactaccttc cccttctcat
     3241 ctttaacagt gttatcgaca tccagaataa ttactctggt ttccacaaaa ctctccttgt
     3301 cattgccttt attctttgtc ttgcttggaa taaatgattg tgatgaattt agtatctcta
     3361 caaactcatc tcttgtaact tctctatagt tatctaaaca cctatctctt acatcagttt
     3421 tttctttttt tgtaactggc ttctctaata atttttcttg atctacataa attggaatat
     3481 taatcattga tgtttccatt tgtgtttcct ccttataaaa ttctgttaaa gactaaaaca
     3541 tacagataat aaacacaaac tctttattac tatatgtttt agtcttattt gtttactcaa
     3601 cctttatact gttccatgaa actatcaata tcagattttt tgaatctaat gaccgtatca
     3661 atttttataa caggtaaccc gtattgagaa acatattttc taatcgttcc tactgataca
     3721 cctagatatt cacttgcctg ctgatagtcc atatactcta gagtaacacc agaaataatg
     3781 tcttctagca taggctttag cactgtaatt atctctttca cttgttgttc aacttgtata
     3841 gaaacaatgc tatcaatgat ttgtagagac atatttcccc ctcctttcgt gattacttga
     3901 acaaattttc taagaatcat cttcgtatta tttgatcaaa ataaaagtat tttgttgtta
     3961 ttaaccgatt aatcaaataa aaaatgatta tcagttcatc gacatacaca taatacctcg
     4021 atacaaaagg ggtgtcaata tgttgtgtga atttatttac aacaccccct ttttgaggta
     4081 tactaatttt aggaggtgtg gtcaatatga taaagcgtcc accaataaat tatttagaac
     4141 gaaaaaagat actcggaaca aaaataaaag ctataagaaa gagtaaaaaa ttaacacaac
     4201 cagcatttgg tcttatgatt aacaatggtc aattgattga caaaaaaact atctacgaat
     4261 gggaaaaggg aacctattta ccaataccag agcgattatc ccgaattgct gatttgggaa
     4321 atatgagtat agaggagtta gtttgtggca atgtagaaga atatattttg ggaattattc
     4381 tttatagaga tagcattgta ctagatggta taacatttcc agataaaaac ctgttccagc
     4441 atcttcgtca acagttccca ccagtacact ctaatttaga tacatggctg gatagatatt
     4501 ccaaattaga accagagatg caagaattta ttgctaacaa gacttgtaat aaagttaaaa
     4561 atgaaaaaat tagtcttttc aatatcttaa aaatagaaga attattcatc aatgctatta
     4621 tagaagaatt tgacaataac attcttctgc tcactagcag tatagaggaa caactagaag
     4681 aaatgataga tgaagggata catagtcaag tggaagacat gaattatccc gaagaagctg
     4741 taaacgaaat tattgataat ataaacaagc taaaacaaac gatttcatca attgggaaaa
     4801 aatacactaa gaaaaaaatg aagggaggtg ataccatcta gtggtaagta ctccttgtaa
     4861 actaagagga gatgatttca tggcaaaaat atcaaagtac aaaaagaaaa acggtcaagt
     4921 ggcgtggatg tataaaggac acattgccac cgatccacga actggtgaaa aaataaatac
     4981 tacgagaaga ggttttagta gcaaacaaga agctcaaaaa gattatgacg agtacagaca
     5041 tcaaatatta tacggtgtta aaaagaaagc acctgatatg acatttgaag acctgtataa
     5101 tgaatggata actcatcagc gtaccagtgt taaagcttca acaatcgcaa tctcagtaag
     5161 atacgcaaat aatcaaatac ttccagcatt tggtaagctt aaactatcga atatctctgt
     5221 cccatattgt caaaaagtgg tagatgaatg gcacagtaaa tatgaaagtt acgattatat
     5281 gagaaaacag actgcacaaa ttttacgcta cggggttgca atgcaatata ttgacaataa
     5341 tcctatggaa aaaacacttc ttccacgaaa aaaagagtat gagaaaaatc gtaaatttta
     5401 ctcaaaagag gagcttaata atttactgga tgcttttaaa gattttggta acatgaaaca
     5461 atacgccttc ttcagattat tggcatacac aggtatgaga aagagtgaag tactcgcttt
     5521 acagtggaaa gacatagaca cgtttaataa agaactacat gtcaataaaa ctcttgctgt
     5581 agatgaattt ggtaaagtta taattcaatc tccgaaaaca agagcttcta gacgagttat
     5641 ctctttagat actgagactc tttctatcct caacaactgg aaattacagc aaaaagaaga
     5701 gtatttaaaa cttggataca atactagctc taaagagcaa catgttttta caacagttaa
     5761 aaacactcta tacattccaa acactgttaa tgattggtta agatatattt tgaaaaaata
     5821 taacttgcct cgtattacac ctcatgggtt tagacataca catgctagtt tattattaga
     5881 agcaggagaa tctgtcaagg tagttcaaca acgattaggg catgaaaata gtaaagtgac
     5941 attagacatc tatgcacata ttacaaataa tgcacctaag aaaacaggtc aagactttgc
     6001 tgatatgatg gctcatcagt aaaagagctg gtcaaaagct ggtcatttct agtatataga
     6061 caaaataaaa aagctagaac ccttatatac caaggattct agctcctata acaagtttat
     6121 cctacactgc cttccatctc ataactgatc aatcggttga gttcgactgc atattccatt
     6181 ggaagttctt tggtgaatgg ttcaacaaag cccatgacga tcatttcagt tgcttcagat
     6241 tcggtcaggc ctcggctcat cagatagtag agttgttctt ctgagatttt tgagactttg
     6301 gcttcgtgtt ctaaagagac ttggctgttg tggatctcat tgaatgggat cgtatcggat
     6361 ttcgaccatt cgtccatgat gatcgtgtca cattcgatat gagagatcga acccgcactg
     6421 tttttggcaa aggttacttg tcctcgatag tttacttctc cgccgtcttt tgaaattgat
     6481 ttagagacga tagagctaga tgtatttggt gcattatgga tcatttttgc acccgtatct
     6541 tggatttggt ttgctcctgc aaaggcgatg gagagcatgg tgcctcgtgc accttttcca
     6601 tctaagtaaa cacttgggta tttcatcgtt gtttttgcac ctaagtttcc gtcgatccat
     6661 tcaacggttg cgccttcgta tgcttttgct cgtttggtta ctaagttgta cacattgtct
     6721 gaccagtttt ggatcgtggt gtaacggcaa tacgcatctt ttcttgtaaa gatttctacg
     6781 atggcagcat gcagactatt acttgaataa gtaggtgccg tacaaccttc gacatagtgg
     6841 atgcttgctc cttcgtcaac aatgatcagc gtacgttcga attgccccgt gttttccgca
     6901 ttgatccgga agtacgtttg taatggaaca tcgactttga cgccttttgg cacgtaaata
     6961 aaggtgccac ctgaccatac ggctgaattc agcgctgcta atttgttgtc ggttggcggt
     7021 acaagttttg aaaagtactc tttgaataat tcagggtatt ctttcaaagc agagtcagtg
     7081 tcagtaaaga cgattcctaa cttttcgaat tcatctttca tattatggta cacgacttct
     7141 gattcatatt gtgcggaagc accggctaga taagctcgtt cagcttctgg tataccaatc
     7201 ttttcaaatg tatctttgat tttttctggt acgtcttccc agtcacgagc gggtttgtca
     7261 cttggttttt ggtaatattt gatggcatcg aaatcgatgt ctgaaaggtc gggcccccat
     7321 gtttgcattg gcattttatt gaatgtttct agagatttca gacggaattc aagcatccat
     7381 tctggttcgc ctttgattct tgacatctca cggatcactt cttctgtcaa gccttctcct
     7441 gtactgaaaa ccggttcgac atcatcgtga aacccgaatt tatattcttc taattctggt
     7501 acgcccatgt tctcactcct cttccttgtg gtaatgatgg aaagctgcgg taccatcgtt
     7561 ttccattgct tttcctagtg ctttccaggc aagtgtcgca catttgatcc gagcgggaaa
     7621 tttagctaca ccaccaagca tagcagcatc gcctaattgg tcgggatctt tgacttcttt
     7681 tccttggaca agctgtagaa agtctacagt taaatgttct gcttcttcta ttgattttcc
     7741 aatgacggca tctgtcatca tcgaggcact tgctgtactg atggaacagc cgctgccgtc
     7801 aaaggcgata tttttgatga ttccatcttt tacatcaact tgcaattcga tcacatctcc
     7861 acatgtgggg ttgttcaatt cgatcttgct tgtcgagtca gtcaagcttc cacgatgatg
     7921 tggatgggaa gaatgatcca agatcacttg acggtataaa ttgtctaatt tagatagtcc
     7981 catgtttgaa aaactccttt gttgccatga ttgcttcaac taaacggtcg gcgtcttgcg
     8041 ttgtgttgta gaaataaaag ctggcgcgag cagtcgctga tacttcaagg tacttcaata
     8101 gcggttgcgc acaatgatga cctgctctaa cggctacccc ttccatgtct aaagctgtcg
     8161 cgacatcatg gggatgtaac ccatccaaat tgaacgcaat gactcctgtc cgaaaattcg
     8221 ggtcttgcgg accataaaca gtcaatccat cgattgcttg taattttggc aacacataag
     8281 cggctagttc ttcttcatat cgatggatat tgtccatgcc gagttcttgc aaataatcga
     8341 ttgcatgacc taatgcgata gcgccagcga tatttggtgt ccctgcttcg aatttccaag
     8401 gtagttcttt ccatgtactg tcgtataatt cgacaaaatc gatcatttcg ccaccaaatt
     8461 caacaggttc catttcttct aaccattttc gtttaccata taaaacaccg atacctgttg
     8521 gtccgcacat tttgtgtccg ctgaaagcaa agaaatcaca gtctagtgct tgaacatcaa
     8581 tggtcatgtg cggggcagat tgagcaccat ctactacgat gaccccgccg ttttcatgga
     8641 caagttcagc taattcttga acaggattga tgacacctaa gacattggat acatgagcaa
     8701 tggagacgat tttggttttg tccgtaatct ttttcgctgc atcctccata tccaggaagc
     8761 cttcttctgt tagttcgata tatttcaaga cagcacctgt tcgttttgcc aactgctgcc
     8821 acgggataac attagaatga tgttccatgt aagagagcac tatctcgtct cctgctttga
     8881 tatagcggtc gccgaagctt ctggctaccc aattcaagct tgtcgtcgta ccacgagtaa
     8941 acagcacttc tgctgtttct tttgcatgga tgaacgcccg tactttttct cttgcttgtt
     9001 cataatcatg ggtcgcgcgt tctgctaacg tatggacacc gcgatgaaca ttggcgttat
     9061 cgtgttcgta atagtgcgct aatgcctgga gtacttgttt tggcttttgg gtcgtcgctg
     9121 cattatccag ataaactaaa ggttcatcat tgacgtcttg aaataagata ggaaaatcat
     9181 tgcgtagctt tttagcatcg atcatccatt caacttccct tcgattactt cgactaattc
     9241 tttccgaact tgttctacag ggattgctgt taagacagaa ccgaggaatc ctcgaatcac
     9301 taagcgctct gcttcttctt tatgcaatcc tcgactcatc agatagtaca tttcttctgg
     9361 atcaactcgt cctacactgg cagcatgtcc agcagttact tcgttttcat cgatcaaaag
     9421 aataggattc gcatcaccac gtgctttatc agaaagcatc aagacacgac tttcttgttg
     9481 ggcatctgca ccttttgccc ctttcaagat gtggccgata ccattaaagg tcaatgttcc
     9541 tttttctcgg atcactccgt gttgcaaaat atgcccgatc gtatgagggg ctttattggt
     9601 tactcgcgta tcgattcctt ggatttgtct gcccgagctg attgccacga ttttgacttc
     9661 tgcgtgtgca ccttctcctg ctaaatctga gtcaaagtca gcgatcacat gaccgtcatt
     9721 catgacacca attgcccagt cgacagaagc atctcgtaaa atgtgcccac ggcgattcat
     9781 ataagaagta atattttctc ctaattgatc tacggctgaa tatttgattt ttgaaccagc
     9841 tttagcgatg acttccacga tgatattacc tgatgatttt gctacttgtt ctttggttgt
     9901 ctggaaacgt tccagataag aaaattcact atgttcatct gccacgatca acacatgctt
     9961 gaagaagtgc tcatcggatg cgccatcttg aatgaataag gactcgagtg gttcatcgat
    10021 cacgacattt ttaggcacat acaggaaaat accgctgttc ataaaagcta catggagtgc
    10081 agtcaattgg tcttcgttca tgtttactgc ttttttcata taatattctt ggactagttc
    10141 tggatattcg atcattgcag tgaacaagtc ggtaaaaatg actccttttt ctgctaattc
    10201 cacaggcagt tgttcaaaaa tcgtccatga accttgttgg acaagcacag gattgtcttt
    10261 cattgcatca aatgccggaa tcgtgcctgt ttcactgatg gtttgtgttt ctttcacatc
    10321 aaataacgac cagcgatgga atttcacccg atcgatatgc ggcaatggca gttcatctgc
    10381 tttcgctagt gcgtcttgac ggaaggttct catccaatca ggttcgcctt tacttaaaga
    10441 aaaatcattt accgcgtcaa gataatcgag ccagtttttt tctttcattc ttgctccccc
    10501 ttacgcttct tcttctttat agtcgattcc taattcttta ctgataccag cgtagccttc
    10561 tgcttccaga cgtttagcta ggtcagcatt ccctgtcatg actactcggc cttccatcat
    10621 gatgtgaacg acatcaggtg tgatatagtt caataatcgt tgatagtggg tgatgatcaa
    10681 tgcaccgaaa ttgtctccgc gcatttcatt tactccttta gcaacgactt tcaaagcatc
    10741 gatatccaga cctgaatcga tttcgtctaa aattgcaaat gttggttcta acatcaacaa
    10801 ttgcaggatc tcattccgtt tcttttctcc gccagaaaaa ccttcgttca gataacgttc
    10861 agccatttct tctggcatat ttagtaaagc cattttttca tctaactttt tcaaaaatgc
    10921 cataacagaa attttgtcgt tttcatcacg tttcgcattg atcgctgcac gcatgaattc
    10981 cgcattcgtg atacctggta tctcacttgg atattgcata gctaaaaata agccaagtcg
    11041 cgcacgttca tctacttcca agtctaaaac atttttcccg tcaaacaaaa tttcgccttc
    11101 tgttacttca tagtttggat tgcccatgat agcggcagat aaggtagatt ttcctgtgcc
    11161 gttaggtccc atgatggcat ggatttctcc ggttttcatt gttaggttta cgcctttaag
    11221 gatttctttt tcctcgatcg acacatgtag attttttatt tctaagacag acatgcatta
    11281 tacccccaaa ttctctttcg ttctcactca ttttagacta attgagaatg aagcgcaatg
    11341 accttcctta ctaaaatcaa atatctttt
//
LOCUS       DAFKHN010000079        11258 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFKHN010000079 DAFKHN010000000
VERSION     DAFKHN010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.079"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1105
                     /locus_tag="LY912_002250"
     CDS             <1..1105
                     /locus_tag="LY912_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBM6955907.1"
                     /translation="IIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMF
                     SFEGIKGYGYVVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGL
                     FVSYVAHQYQVFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLK
                     KYTDSLEKDQEKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKF
                     EYRYLKNIKNEYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILD
                     NAIEASIESQDRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLG
                     LSSIEEINKKNPNMFVNYQNDPYQFTTQVILLF"
     gene            1120..1872
                     /locus_tag="LY912_002251"
     CDS             1120..1872
                     /locus_tag="LY912_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6955908.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(2575..2790)
                     /locus_tag="LY912_002252"
     CDS             complement(2575..2790)
                     /locus_tag="LY912_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HBM6955909.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(3002..4321)
                     /locus_tag="LY912_002253"
     CDS             complement(3002..4321)
                     /locus_tag="LY912_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBM6955910.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(4493..4729)
                     /locus_tag="LY912_002254"
     CDS             complement(4493..4729)
                     /locus_tag="LY912_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HBM6955911.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            4987..7140
                     /locus_tag="LY912_002255"
     CDS             4987..7140
                     /locus_tag="LY912_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HBM6955912.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            7109..8524
                     /locus_tag="LY912_002256"
     CDS             7109..8524
                     /locus_tag="LY912_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBM6955913.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            8557..9591
                     /gene="sppA"
                     /locus_tag="LY912_002257"
     CDS             8557..9591
                     /gene="sppA"
                     /locus_tag="LY912_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBM6955914.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            9593..10114
                     /locus_tag="LY912_002258"
     CDS             9593..10114
                     /locus_tag="LY912_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBM6955915.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            10111..10497
                     /locus_tag="LY912_002259"
     CDS             10111..10497
                     /locus_tag="LY912_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBM6955916.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(10993..11065)
                     /locus_tag="LY912_002260"
     tRNA            complement(10993..11065)
                     /locus_tag="LY912_002260"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11030..11032),aa:Lys,seq:ctt)
BASE COUNT         3909 a         1676 c         2017 g         3656 t
ORIGIN      
        1 tataatcgga agttatttta tattaaagga aaagaagaaa actaatatag tgcttttaaa
       61 taaattacta ttatgtatgc ttattgatga tttcagatct attattactt ccatggttat
      121 gacgtatatg ttttcatttg aagggataaa agggtatggt tatgtagtat tccagataat
      181 gcttgattct ttgtttttgc tgatgtttat ttggttatat agaaaattag ctataaatag
      241 gattgttgaa cagtccagtt ctaaacttac tgctatattc atgatttatt tacttacaat
      301 tggtttattt gtttcttatg ttgctcatca atatcaagta tttgatcatt ttgtgtttgg
      361 tgtcttaata tttttaatca ttcaaatgtt tgttgttcta tttttattta ttagaataac
      421 tattaggcaa cgagaacaat atgaacagca attgaaaaga aaagaattgg tttatctaaa
      481 aaaatatact gattcactgg aaaaagatca agaaaaattt gccagattta gacatgacta
      541 taaaaattta ttgctgagtt taaaagaaat cgctaatcaa aaccatgatt cgatattgga
      601 aaaagaaata aaagaattag agatctattc taattcttat ctaaccaata agtttgaata
      661 tcgttattta aaaaatataa aaaatgaata tttgaaaagt ttgttgatag cgaagctata
      721 ccaagcaaat aacaataaga tttgttgtaa attcgaatgt ccaagtacta ttattgaagt
      781 tcctgttcca atatttgact gtattagggt gcttggaatt attctcgata atgcaattga
      841 agcatctata gagagtcaag atagagaact gtctctagct atttaccgag atgataaaca
      901 gatagaaatt tcgatatcga atagttgtag agagatacta ctctctatag atactctaat
      961 gaaaaaagga ataacaacaa aaaagggaca tcaagggtta ggtttatcta gtatagagga
     1021 aatcaataaa aagaatccca atatgtttgt gaactatcaa aacgatccgt atcaatttac
     1081 tactcaagtt attttgttgt tttgagggaa ggaggattta tgagttatcc aataatatta
     1141 tgtgaagatc aaattataca attaaatcag ttagaacgaa ttattgataa tttcattctt
     1201 tttcacgata aagtatttaa gatagtattg aaaacacaaa gtccgttaga agttaaaaaa
     1261 tacctcaaac aattccgacc aaagcaagga atatatttct tagatattga tttaaatcat
     1321 gaagttaacg gtatagaatt agcagaagta atcagaaaat atgatgttca agcaaaaatc
     1381 atttttacaa ctactcatga tgagatgtta cccgtaacaa taaaaagaag agttgaaacg
     1441 ttaggatttg taacaaaaga tcaaacacta gatgagtatc gaaacgagat tgttgagtta
     1501 ttgttattag cgcaagaaag gatagatgca acaaaacagg ttacgaatca agcatttgtt
     1561 ttttccatag gttctcaaac atttactttt gatataaatg acatttattt tgtagaagct
     1621 tcaaaattac cacatagatt atcattgtgt actaaagatg ggcagtacga attttatgga
     1681 agaattagtg agcttgaaaa gaaatatcct atgttaacaa gaattagtcg agcgtgttta
     1741 gtaaatatct ttaacgttaa agaaatagat tttaaaaaac gttcactata ttttgattca
     1801 gagttggcca gaaactttac tttagggaaa gcacaaaaaa ttaaggagaa gttgaaagaa
     1861 agcactgttt agtggttttt tctttaggga gattgcattt ttctaataaa atagattcct
     1921 tcactagtgc aaatttttct gaatcctatt aaagttgtac caatttttat agctgttatt
     1981 agttacgtgc ataacagcaa tattagttac tggaggaata tttctatggt ctggaaccaa
     2041 aaaagggcca aatgaatagt tcttttcttg tttttattaa gtaccataaa ggggaattaa
     2101 aattaaatgt atggtggaag atgcgaaaga tttggcaaat tctactaatt tttagaaagt
     2161 gtttttcatt ttttagttaa aaaatttgtc ctgtcaagtg caatcctatg attgtacttg
     2221 ataggatttg agataattac tttcctgttt ttataaattt aacttgcagg aacaggcttt
     2281 aatgcacatc cgacaagtac attaccaata cctcctgtaa cggccgaaat aggtcctcct
     2341 gcagcaccaa ctacagcgct gcaagtcctt ttgtaaaaat atctctacca ttacatttcc
     2401 aaagaatttt tatctgactt taataaaaga taaaaattta atataattat aaaaactagc
     2461 acaagaagct ttagtaaaaa gttctgtcca ttccaaactt ttgaaaagat aaagaacata
     2521 cctatgttcg taatcgacac aaaccaatct tgaggtttga tattttttaa ttgtttacgc
     2581 accggtccac atgctgaatc cagcacctaa taaagctcca cctacaccac aagcagctat
     2641 tgcataaggt cctccggctg aacaaagttt tactcctgct gttgccccag aaaaagtagt
     2701 gcctaaaact cccacggcac tcccaccttg aatatttttc aactcttctg aagataatat
     2761 aaatgttgtt tttgtgtttt taatatgcat actacttacc tgaataattc atagctttaa
     2821 ttctttggca cattttattg aaatatgtat cactaatatc cctatcaact gattttgact
     2881 aaaaagttac ttcaaacatt cactgttcaa aaatattgag gaataaattt tgggtgtaag
     2941 gcattttgag catacttctc cctggataac ttcccagtaa aaaaatcgtt agattgttgg
     3001 attagatcca ttgactggct cgcctcaggc gagcaaagac cctgtagaat tcattctgat
     3061 acacatgata actagataat ttgagataga ctcgtctacc cgtttggact aatttcccag
     3121 caactttcag aaacttcaat cgaatagaat gaatggtcat tcccttttgg acttcttcaa
     3181 agccaatcgt tcttaagaag ttgactaagt tgtaagctat caagctgagc atcattcgga
     3241 catgattctc caaaaagcga ggactgtctg ttttgtcaaa gtaaaagcca gctttcgctt
     3301 ctttaatgaa gttctccatt gtgccacgtt tggcatagat agaaaagatg gtatcaggag
     3361 aaacattttc tgatagattc gtcacgataa attcatgtcg aaagagtagt tcgcccgctt
     3421 cacgtgttga gcgtatacac acgcgacgac tttgtgacca ggattgtgct tgataagtgg
     3481 tcgagaagta ctgaacttct cgttcttccc acttttgatt atcgccataa agtactgatt
     3541 tctcagctat ttgacctagt ctacgattat tcttcagtcg aataacataa tgactctttt
     3601 ttgattcaca cgaatcatac acaccaggtg tagcgaaccc gctgtctcca cgaaccaaga
     3661 tgtcagtgtt tggtagagag tgattatagt gctctaataa aggtgtgaga aactccttta
     3721 cgccttttga tgtatattga tttcctgaac gtagttcagc ttttaagaag tcaccagtca
     3781 atccgtcaaa agctaccaat ggatggtaac cataggtttg gtagtgtgta ttataattcg
     3841 tttgttcttg gtgaccaaat gtatctgaat gggtcgaatc taaatcaatg attaattccg
     3901 tatcattacg gatgaggcgt gctttatcga taagttcttg gttcaaagct tgaagttcat
     3961 ggatattctc ctcagatagt cgatctaaaa atcgggaaag tgaagattga gaagcgagtt
     4021 ctttcctatc taaaacagct ttaaacacag gatcttgtct caggagatta gctgcagaat
     4081 cagctgagta accagcaatt aattgcataa tgaactgctc aagtatggat aagttgtcat
     4141 gagtaaaata cgctcgttcg tcttcaatgt gaatgtgttg cttagccagt tcagaaaaac
     4201 caaagatgtt catcagctct ttcactagga cgagacccga atcactcgat aattgaccac
     4261 ctgtatgaga aatagtgata tttgaattga attttacttg gtttttgtgt aagctagtca
     4321 tgaaaagaac tcctttcttt tggttggttt agtcacttta accatagcag aaaggggttc
     4381 ttttttcatc acttaacggg tgaagatgaa aaagtaattg taagctgccg tgaggcagtt
     4441 tcacatggtt ttaattaaaa gtatgaatta ttcaggtact tattctcctt ttttattttt
     4501 ttcgagcatc ccagccagct gcagcacctc cagcgacagc tccatataac cctccaacaa
     4561 caccgcaagc tggtccgcaa attgctgttc ctaaacctgc accacctact gcccctgtgg
     4621 taagtccacc tacaacttgc cccaattttc cccaagcatt attgcctcca ccaacagttt
     4681 gtgcatttcc acaatactta gttcctttac attttgcatg tttaaacacg cttctttaaa
     4741 taatattttt tacggtgcta ctgtaacata cgtatttgat taacagtaaa aatcttcctg
     4801 aaacttatca agtttattct tgaatagtaa aatttccaaa ataaatttga ttcaggaatg
     4861 aaaaagttag tgttcaagaa ctgttttcaa agtttttgtg gaattatgag acaatatttt
     4921 cactgtatta aagctatatt gagaattttt ctataaaaat tttttagaag gagttgtgtt
     4981 agataagtga taaaatcatt tccttttgtg cagcaacaag atgaaaaaga ttgtggtgtt
     5041 gcttgccttt cgatgatttt aaaatatttt aaaactgata tcccgattca taaattacgg
     5101 gacctatctg ggactgattt agagggtact tcagcatttg gattgaaaaa gacatttgaa
     5161 aaattgtctt ttgattgtat ggctattcaa gcagatagtg agatctggaa agaaagagat
     5221 cttatcttac cattaattgc acatatattg gttgataaca gctatatgca ctacgttgta
     5281 atttataaaa cgaagggaaa cgtactatgg attgcagatc ccgctaatgg aaaaaataga
     5341 aaaacgattg aagcgtttca aaaagaatgg acaggtattc ttttattacc tatgcctaga
     5401 gaaacttata ttcctattaa agaaaaagta gctggattaa gttctttttt gcctataatt
     5461 tggaaacaaa aaggattagt attccacatc gttttagcat cgattttcat tacgtttttt
     5521 ggcataggaa gctcatatta ttttcaaggt attcttgatt ttttcatccc taatcaagca
     5581 cgttcaactt taaatataat ttccattggc ttgatcgctg tctatttatt tcgggtattg
     5641 tttgaatata gtcgtagtta tcttcttatt attttaggac agcgaatgag tatggcaatt
     5701 atgcttcagt atttcaaaca tgtgttaact ttaccaatga atttttttgc tacgagaaaa
     5761 tcaggggaaa ttatttctcg ttttcttgat gccagtaaga ttattgatgc tttagcaagt
     5821 gctacgttat caatattttt agatattggt atggtgttgc ttgttggggt tacgttagct
     5881 attcagaata gtacgttgtt tttaatcact ctatgctctt tgccttttta tgtagttgca
     5941 atattcgctt tcgtgaaaag ctatgaaaaa tcgaacaggg aagaaatggc agccggtgca
     6001 gctgtaaatt ctagtatcat agaaagtctt aaaggaatag aaacaattaa agcatatagc
     6061 ggtgaagaga aagtatataa ccgtatagac catgaatttg ttaaattaat gaaaaaatca
     6121 tttcgtacgg ttacgcttga taatattcaa caaggaatta aacatttgat tcaattaatt
     6181 agcagtgcat taattttatg gctaggttct tattttgtta tggataatag aattagtcta
     6241 ggtcaactta tcacatacaa tgctttacta gtatttttga cagatccttt acaaaacatt
     6301 attaatttac aagtgaaaat gcaaacggct caagttgcaa ataatcgttt aaatgaaatt
     6361 ttcgcgattg attcagaaaa atcgaaccag tcttttgaat atatgctttc tgaacaatta
     6421 tttcaacaag atatcactgt aaaaaacgtt tcattctcgt atagcatgaa ggccccaacg
     6481 ttgaacgaaa tttcatgtac aattccttcg cacagtaaaa cggctatagt tggagttagt
     6541 ggttctggaa aatcaactct tgcaaagtta tttgttcgtt tttatgaagc atcagaagga
     6601 tcgatccatt atggaaacat taatcactta gacattcctt ttcagatatt acgcgatcga
     6661 gtgacatatt tgcctcaaga gtcatttttc tttagtggaa caatcattga gaatcttata
     6721 ttcggtttag atagcccacc aagtttcgaa caaataatag aagtttgtga gatagtccaa
     6781 ctaaatgaat ttattaatca acagccatta cgttacgaga cattgttgga agaaggtgga
     6841 aataatcttt caggagggca acgacaacga ttagccttag cacgggcttt attaaaaaat
     6901 ccggacatat taattttaga tgaagcaact agtggattag ataccttgtt agaacatgca
     6961 attatgaatt atctcctcaa tttaaaagaa aaaacgatta tttttattgc gcatcattta
     7021 ccaatagcaa aagcatgtga tcaaatttta gttctccatg aagggcattt ggtagaaaaa
     7081 ggaacgcacg atgaacttcg ttttgccgat ggtatctatc aaaaattatg ggaaatctag
     7141 gagagggaaa caatttatgc agaataataa ttggttcgaa cattctagta tctatactaa
     7201 acaacatcat agcttctacc gttgggtgtt ataccctgta attctttttt tatgtattat
     7261 tggattgttt ttaacctttg ctaaaaaaga ggttgttatt cggacaacgg ctcaattgaa
     7321 ccccgaaaaa atagagaagt tacaagtgcc attagaagct aaaataatgg aaaacttcct
     7381 aaaagaaaat caatttgttc ataaggacga tgtgttggtt agattggatt gttctttaat
     7441 agagaatgaa aaggctcaga tagaacaaga aaaccaacgt attactcaac aaataaagat
     7501 ggctcagcta tttattgaaa gtataagtaa aggaaaaaat ttgttttcaa cggatgacag
     7561 ttttggctac agtaatcaat taaagagcat gttgtcagaa aaagaatcac tccgctacgc
     7621 tttgaagcaa agtgaattaa atgatcaaaa gcaattagaa gtatacgaaa agacaaaaag
     7681 acaactagaa aaacaaattg agagttcaga tagtaaatta caagaatggc aacaagtaca
     7741 ggtagcttgg agtaataatc aatcattaaa agatttttca aaagaaatga tggcaaacta
     7801 tgagaattgg caagaacaac taaataatgt ttctgatgat caaaaaaatc aagtgaaact
     7861 gacaatttca gcaagcataa atgaacaaat tgagcaacta aaaaaagaag tagaacagta
     7921 tcagtcagaa aaagctaaat tagttaaacc aactacttct gagaatgaca gaattagtca
     7981 aacggaaaaa ggaaagcaag agctagaaca agcaataaca actgtaaaac aaacagttac
     8041 agagctaaat gaaaaacaag agaagaacca gtcagttatc aaaagtttgg acgatcaact
     8101 ttcaaaagga atactaaaag ctcctgtatc tggaacggtt catttaaatg aagaaacaaa
     8161 gggacaagca gaactagcca aaggaacagt gcttgcagaa atttatccga tccacgaaaa
     8221 atcaaaaatg aaatttacag cacttttacc tgcgaatgaa agtacctata ttaaagaagg
     8281 gatgaaggtt cattttaaat tggatcaaaa aggtggggct ccgattacga tcgacggaac
     8341 tttagatgaa atttcagaaa attctactgc cactgagaaa ggtgtttttt atgcagtgaa
     8401 aggaacgtta aaaacaactc aatcgtttcc gtttcgttat ggattaactg gagagttgtc
     8461 tttaattgta ggagaaaaaa catattggca acaaattgtc gatgtgtttc taaataaaaa
     8521 ataattattt ttactaagaa tataggagga gtttatatga ataaaagaag atggattgct
     8581 gtgggagtag cgtgcggatt attgttacta tccattatcg tcgcgctaat tccaggaaaa
     8641 gataaagagg aagcatcaaa tacaacccta acaggaataa ataagatttt ttacggatct
     8701 aacgaaatca cagaagaaac gttagaagaa ggcgcatcaa ataaaaagat tgtcaaacta
     8761 tccgtcaatg gagttattgc agatacaggt gaaagcaatc tttttagtag ggaacaatat
     8821 aaccatcaga attttttaac acagctaaag aaaattcaag aagacaaagc ggttaaggga
     8881 gtgttattag aagtaaattc acctggggga ggaatatatg aaagtgctga gattgctaaa
     8941 gaaatggcaa aaattaaaaa gctagatatt cctatctata ctgcatttaa aaatacagcg
     9001 gcaagtggag ggtactacat ttctgctggt tcagataaaa tatttgctac ggaagaaaca
     9061 acaactggat caattggtgt cattatttct ggtttaaatt attctggctt attagaaaaa
     9121 cttggcgtaa ctgatgcgac gtataaaagt ggtgcattaa aagatatgat gtcacctcaa
     9181 cacaaacctt cagaggaaga gaataaagtt atacaggaat ttgtgatgag tgcttatgat
     9241 cgttttgtca atgttgtagc aaaaggaaga aatatggata ctaatgcagt gaaagaactt
     9301 gcggatggaa gaatttatga tggtaaccaa gcagtagaaa atgggttggt ggatcaaatt
     9361 ggttactctg aagatgcatt agattcccta aaaaaagaga agaaattaac tgatgcgacg
     9421 gttatagaat ataaaaatga cacaactggc tttgcttctt cttggttagg taataagatt
     9481 gctgaatggc aagggctaaa ggcaactaca tcagatcgtg taatttcagt ttttgaaaaa
     9541 cttggatttt ctgatactcc aaaaccaatg tattactatg gagggctata aaatgaataa
     9601 gaagagtggc attgaaactt tgcctaatta tgtatttgcg ggattttggt tacgattttt
     9661 tgcttttctt attgatttaa tttgtattag catcatcacc catgctacta taggtctctt
     9721 ttacaaaatc atgggactgg aatctgacaa atccattatt actttttatg gtatagcgtc
     9781 attagctatt tatttaacct attttgtact tttgactaag ctgaattcag gacaaacaat
     9841 tgggaaaatg atttttggga taagagtagt gagctttgag gaaaaagagc taagttggca
     9901 aactatcttt attcgtgagt gtatatgtag gtttatatta aaaaattttg tatttcaaat
     9961 tgggtatttg gtggctgctt tcacgcccaa gaaacaacat attggggatt atttttctaa
    10021 cacgtcagtg gttgttattc gttcattaga agctattaac tatggtcaaa aaatttctaa
    10081 ttctaaaaca cttaatctgg agagaattaa atgaataaga gaaaaacaga gtttattttg
    10141 attttaatta gtggaataac agggatttta tgtagtcttt tagcattgat gggtggtatg
    10201 tttctatctt ctattgattc aactacttta aatactacag aactaaccag taaggatata
    10261 gatatgttag tcaatctaag cgggaatgtt gttttatttg gaggaattac cctagttttt
    10321 tcgataatga ttttcataat aggtttttta gtaagaaaaa atcaaaaaac agtggtctat
    10381 ggtattagtt tactcatttt atctattatt ccattttttc ttttaacatt attgtgggta
    10441 attcctggag ttttaggtat tattgcggga ttgatgcttc taataagaaa atcttaatta
    10501 ggcaatgtgt agacaacgtg aaacgattaa tcaattaaaa gctaaatacg ttttgagaaa
    10561 tgataacttg tagtcgatgg aagacatgta gataaaaaaa ctacgtgtct tttatttatt
    10621 ctaatttttt cgaaaaaaag acactctctg attgttgtat taatggaaaa ggggaaagca
    10681 gcaagtaaat ttagtttttc tattaaatat tcttcacttt ttaacctttt atagtactta
    10741 gatttaatcc tatatgttta gagagttcat tggcagcatg attttgcaaa gcttctcgaa
    10801 ttattgttat attagaaact ttactgttca taattatgct tcttttttaa ctcaaagtcc
    10861 aaagggctac agtggacttt gagttaaaaa taaaaagccc tagttatttt gaaaaataaa
    10921 aaaagaacag cgtaaatgtt ttcgaaatgc tttcgcacca acatttacct gttccgtggg
    10981 tttggcaccc aatgggccgt gaggggctcg aacccgcgac ccgctgatta agagtcagct
    11041 gctctaccaa ctgagctaac ggcccgtaca aaaagtactt aataatagta gcactaagaa
    11101 ttttaaaatg caagactaca tttaaagaaa atcagaaaaa tctttacttc cttataggaa
    11161 atcattcata gattattcac atttgctcgc tattatataa gcataccaac aaacaaagtt
    11221 cttgcaagag aacaaaccct aacacttttt tcattttt
//
LOCUS       DAFKHN010000080        11196 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFKHN010000080 DAFKHN010000000
VERSION     DAFKHN010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.080"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            158..1417
                     /gene="lysA"
                     /locus_tag="LY912_002261"
     CDS             158..1417
                     /gene="lysA"
                     /locus_tag="LY912_002261"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBM6955917.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1404..2204
                     /gene="dapF"
                     /locus_tag="LY912_002262"
     CDS             1404..2204
                     /gene="dapF"
                     /locus_tag="LY912_002262"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBM6955918.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2207..3088
                     /locus_tag="LY912_002263"
     CDS             2207..3088
                     /locus_tag="LY912_002263"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBM6955919.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3085..3801
                     /locus_tag="LY912_002264"
     CDS             3085..3801
                     /locus_tag="LY912_002264"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBM6955920.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3807..4502
                     /gene="dapD"
                     /locus_tag="LY912_002265"
     CDS             3807..4502
                     /gene="dapD"
                     /locus_tag="LY912_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBM6955921.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4518..5519
                     /locus_tag="LY912_002266"
     CDS             4518..5519
                     /locus_tag="LY912_002266"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBM6955922.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5516..6877
                     /locus_tag="LY912_002267"
     CDS             5516..6877
                     /locus_tag="LY912_002267"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBM6955923.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6837..7988
                     /locus_tag="LY912_002268"
     CDS             6837..7988
                     /locus_tag="LY912_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBM6955924.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7963..9132
                     /locus_tag="LY912_002269"
     CDS             7963..9132
                     /locus_tag="LY912_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBM6955925.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9307..10686
                     /locus_tag="LY912_002270"
     CDS             9307..10686
                     /locus_tag="LY912_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBM6955926.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10967..11196
                     /locus_tag="LY912_002271"
                     /pseudo
     CDS             10967..11196
                     /locus_tag="LY912_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3730 a         1952 c         2497 g         3017 t
ORIGIN      
        1 tttttataac catttttatt cttattttta aaaaaatatt tcgaaatata ctagacaatt
       61 cagaaaattt tgtttaatat tattccaata aaattcaaat ctttatcaaa tgaaattcca
      121 ataaaaacgg aaaaaaagtg aaaagaggaa tgaaaaaatg acagaattga taattggcgg
      181 agtcacagca agcacattgg cagaaaagta taagacacct ctgtatgtgt atgatgaaga
      241 aaagatgaga caaacgatgc tgtcattcaa gcgaggcttt gtatcgaaac gttttgatac
      301 aaaagtgctt tacgcctcta aagcattcca aacgattgag atgctgcatt tagttcgtga
      361 atatggattc gggctagatg ttgtcagtgg tggggaaatc tataccgctt tgcaagctga
      421 ttttcctaga gatactatct acttccatgg taacaacaag acgccagagg aactgatcta
      481 tgcacttgaa aatgatttgt tgcatattgt tgccgataat ttgatggaag ttgaattatt
      541 agcagaatta agccaacgct atttaaaaaa aatctgtatc atgcttcggt tgaatgtcgg
      601 agtagaagca catactcatg aatatatcgt cactgcgcat attgattcaa aattcggcat
      661 gagctatgaa agtaaagagt gccaacaagc ccttcagttg ataaaagaaa gcagctatct
      721 agagttagaa ggatttcatg ctcatatcgg gtcacaaatt tttgatgtta ctgcttggtt
      781 agctgaaatc gacaaattga cgaattactt aaccgatttt gaccaacctc tttccttgaa
      841 tcttggcgga gggtttggga ttcgttatac acaaaatgat cagccgatcc cagtcgaaga
      901 ggcactaaaa aaactgattg aatatacgga agaagctttg gaaaaacgaa aactgaccat
      961 tcgtcaatta ctgatcgaac cgggtagaag tattgttgga gaagctggta caacactata
     1021 cacgattggt ttcatcaaaa agacaccaca taaaaaatat tactttgtag atggcgggat
     1081 gacagataat atccgtccag ctctgtatca ggcagaatac gattgtgatt tagcagcaaa
     1141 actgtcggaa gaaaaaacag agaaagtgac gattgcagga aaaatgtgtg aatcaggcga
     1201 tgtggtaatt aaagaagctt atttgccgaa agcagaatcg ggtgatcttt tagctgttta
     1261 ttccacggga gcttatggat actcgatgag cagcaactac aatcgagcga cacgaccagc
     1321 agttgttttt gtcaataatg gccaatcaag actgattgtt cgcagacaag cattttctga
     1381 tctactaagg ggggaagttt cctatgatcc ttcataaata taatggctgc ggaaatgatt
     1441 ttatcttatt agattacgca gaagacacag attatagtca attagccgct tctttatgca
     1501 caaaagaaaa atatgatata gacggattga tcgccgtaaa aatcgatccg ttggaaatga
     1561 tctattacaa caaagatggc agccgcgcgc cgatgtgcgg aaatggcatt cgctgttttg
     1621 ctcgatacgt aaatgatcag aacatgatga atgaacagga attcaacgta gagacattag
     1681 caggcacaag aaaaattacg gtgttggatc cctcaccttt ttattgcagc gtagatatgg
     1741 gagtgccaga tgattctccg gaaaaaatca aagctaatca aacttatcca ataaaaaacc
     1801 aggaaataga gatcaatggt gaaaaagtaa cgatcactag tttattttta ggaacgattc
     1861 ataccgttgt ttttgttgaa aatgcgcgtg aggaagtctg gagaaaaaga ggtgaactga
     1921 tctgtcatca tcctttgttc aaagaaaaaa ccaatgtcaa ctttgtagaa gtagtcaatg
     1981 aacaagaatt gatcgtccgt acctatgaaa gaggagtagg ttggacactt gcttgcggta
     2041 caggttgctg tgcctcttat gtggttgcta aggaaactgg gaaaatttca gcagatcagg
     2101 tagttgttca cttggaacaa ggagacttga tgatctctgg tgaggatgcg atacaaatgg
     2161 ctggcccagc agttcatgaa tggacaagaa tattggagga atgaagatga taaaaggttc
     2221 gatcgtggcg ctgatcacgc cgatgaatga agagggatca gtagattatg ctggtttgga
     2281 aaaattgatc caattccatt tagatgaaca aacagatgga ttattagttt taggtacaac
     2341 aggagaatct tctacgctca cacaatctga ggaggagcag atccttcaac tgacagtaaa
     2401 gaaagtggct ggccgtgtgc cggtgattgc aggagctgga acgaataata cgaaagaaac
     2461 gattgaaaaa gcgaagcatt ttgcttcttt gggggcagac gcacttttgg tcatcacccc
     2521 ttactacaac aaaacaagtg atgcaggact agctgctcat tttacagcaa ttgcagaagc
     2581 ctcaccgatt ccgcttattt tgtataatgt tccttctaga acaggcatgt cgattccaat
     2641 ccatgtatta gtaaatttag cagaacatcc taatatcatt ggtttgaaag aagcctcagg
     2701 agatatggct tatgtgatgg atgccgctcg gttgattgga gaagaattct tcctttacag
     2761 tggaaatgat gatttgatcc taccagtaat gagtgtagga ggaagcggtg taataagtgt
     2821 atgggcgaat atccaaccta aaatagtcca tgaattagta aaagatacgc aggacggaag
     2881 atggcagcaa gcaaaagaaa agcaattaaa tgcacttgaa ctgatccatg ccttgttcag
     2941 tgagaccaat cctattcctg tcaaagcagc catgtcatta ttagacttac cttccggacc
     3001 tctacgcctg cctttagttt ctctttcaaa agagaaaaag aaacaattag ctcagctttt
     3061 gttaaaagaa aggacggttg aaaaatgaaa atcggactga ttggcagtgg acagatggga
     3121 aatagagtcg aagaagttgc acaagaaaga ggagatacgg tccttctttt acggacggca
     3181 cctaaagaag caactacgct tgcttttacg gaactgccag aactgcttat tgatttttct
     3241 catccagata atttagagaa aatcctttcg tatagcttat catatcaact tccgttagtc
     3301 attggcacga caggttatac acaatcacag ttccaagaaa taaaagaaca tgccaaacat
     3361 gtacctgtga tgtatagtgc taatttttcg ttcggcatca tggtgatgaa tcaactaatc
     3421 aagcaagcag ctgcaatgtt gcaaggctgg cagatcgaac tgattgaaaa acatcatagt
     3481 cgtaaaaaag atgcaccatc tggtactgca aatatgctgc ttcaaacaat ccaagaagtg
     3541 caaaagctgc agcccgtata caactggcaa gggaaaaaaa gagaagaaaa ccaaattggt
     3601 gtacacagta ttcgtgcagg ttctttacct ggtgaacatg atgtattgtt tgctgctact
     3661 gatgaaatat ttacgatcaa acatgaatct ttttctaatc gaatctttgc tgcaggcgca
     3721 gtagaagcag cggactggtt gaaagatcag tcaccaggtt attacaaatt agaagattta
     3781 ttaatggaca aaggggtgta aaaaacgtgg aagctcaaga aatcatccgc tacattcaaa
     3841 cggcatctaa aaagacgcct gtgaaagtct atctgaatgt aaccgagcca atcgaattta
     3901 aagaaagtaa agtttttggt gaaggaagca gcttcgttgt ttttggtgac tatgagacga
     3961 ttgctccggt tttagaagct gaatcagaaa aaatcattga aatcgaaatc gaaactgctg
     4021 caagatacag cgcagttcct ttgctagata ttaaaaaaat taatgctcgt atcgaaccag
     4081 gtgctattat cagagatcaa gtgtcaatcg gcaacaatgc cgtgatcatg atgggagcga
     4141 ttatcaatat tggtgcagta atcggtgaaa acacgatgat tgatatgggt gctgtcttag
     4201 gtggacgagc gacagtgggc aaaaactgcc atattggtgc aggagctgtc ttagcaggtg
     4261 tgatcgaacc agcatcggcc aaaccggtta tcgtagaaga cggcgtactg gtaggtgcga
     4321 atgcagtgat tgttgaaggt gtccatatcg gaaaagatgc agtcgtggca gcaggagcag
     4381 tggttttaga agatgtggca gcagaaactg ttgtcggtgg aatacctgca cgtgtattaa
     4441 aaataagtga tgatcagaca aaagaaaata cagcattgat tgctgcgtta cgcgaattat
     4501 agaggagatg gagaaaaatg cgcgaaatag atacctgtat tgtgggggca accggattag
     4561 tcggccaaac gatgctcaaa gtgttagaag aatatgattt tccagtagga cgattgaaat
     4621 tattagcttc aaaacgttca gccggtaaag tttgtgtatt caagaaaaag aaacacactg
     4681 tacaggaatt gacagaaact tcatttgaag gatatgattt agcgctattt tctgcaggtg
     4741 cttctgtatc caaagagttt gcgccaatcg cacgaagtca gggactattt gtcatagata
     4801 attcctcagc atggcgggaa gattcggata ttccattaat cgttccagag gtcaatctgg
     4861 aagactatac attgaatcgg ctgattgcaa atccaaattg ttcaaccatt caagcggtac
     4921 ttccgcttaa agctttacaa gaagcctttg gtatccagcg agtcaattat tcgacctatc
     4981 aagcagtttc tggttccggg caaaaaggca ttgaagatct tcatcgtacg caaaatgacg
     5041 aggaaccagt tttgtatcct tataatatta gccaaacggt gattccggaa atcgatcagc
     5101 ctttggaaaa tgggtataca aaagaagaac agaaaatgat aaatgagacc cgtaagattc
     5161 tgcatcagcc tgctttgcca gtatcagcaa cctgcgtacg tgtgccaatc gaaaatggac
     5221 atggagtctc tgtggcagtt caactgcaaa aagagtttac gacggaagaa attagagagt
     5281 gtctcagcca gtttccaggg attcaattag aagatgatct agcagcacat aaatatccga
     5341 cgagcattct tgctagagga acagatatgg tttatgttgg gaggatcaga aaagacactt
     5401 ctttagagaa cggattgttg ttctatacga ctgccgataa catacgcaaa ggagccgctg
     5461 cgaatgccgt acagattgct gcagctttaa tgcagaaaat agcggaggtg gcaagatgag
     5521 taatacgctg aaagtagcga aattcggcgg aacatcgatg tctcatgaag agcaattcaa
     5581 aaaagtccgt acaattgttc tttcagatcc caatcgccaa gtgatcgttg tttctgcttt
     5641 aggcaaacgt acgtcagatg atgacaaagt aacagactta ctttatttga tttatgctta
     5701 ccttcagcat catgttgatt ggacacccct ttggaaaagg atttgtgatc gtttcattca
     5761 agtaagagat gttcttgccc tgcagttacc tattgaagat gaactagcac gcatacagaa
     5821 acaactggaa gacgaaaaga taactgaaga ttatttagta agtagaggtg aatatctgac
     5881 tgctcaactg atggctgagt atcttggtta ccagtttatt gacgcaaaag acctgatttt
     5941 ctttgactat gatgggaaaa tcgatcagga aaaaacagca caggaaatca caaaagcatt
     6001 taaaagatat ccgaaaatgg ttgttccagg gttttacggg gcgaaccctg caggaaaaga
     6061 aaaattattg ggccgtgggg gaagcgacat taccggcgcg atactggcga agatgttgca
     6121 agcggaaagt tatgagaatt ggacggatgt ttcaggaatc atgatggctg atccgcgaat
     6181 catcgatcat cctaaaatca tcgaggaaat ctcttttaga gaactgagag agatggctta
     6241 tatgggggct aacgttcttc atgaagcagc tgttttccca gttcaagagg ctgatatccc
     6301 catccaaata aaaaatacca atgatccttt cgctcaaggg acaaaaatat cgaatcacga
     6361 aatagaaaag gaaaatggac tgacaggaat agctggacgc aaggattttc tttccatcac
     6421 tttattcaaa cgtcatatgt ccgatgaaat cgggtttatc tggaaagcaa tgagcatttt
     6481 tgctaaacat gagatatcaa tcgaacatat tccttcaggg atcgacaata tcggagtgat
     6541 cgtctcagca gaagcgattg ccgataagtt atttctcatc acgaaagaat taaaagaaac
     6601 acttggcgtg gaagaaatcg tcgtgatcga agacttagct ttgatctctg tcgttggggg
     6661 tccgcataaa gaattgattg gattatctgg gaaagtgtta tcgatattga acaaattaga
     6721 aattcgcaca tcgatcttat cacaaggagc acaggagttg aatctgatca tcggtgtacc
     6781 gaataatcaa tatgaaacag tagtgaaggg tatctatgaa gggatggtga atacggatgc
     6841 tgaaagaata tcgaatggca ctccatcaaa ttcctgaaat cgggtttcat gaattcaaga
     6901 caaaaaaata tttatatgaa caagtaaaaa acagcgaggc cgttatccat gaaatcggcg
     6961 aaacaggact actcctttat tttgataatc agcaagaaga aacgattgct tttcgaacag
     7021 atatcgatgc actgccagtc aaagaagaaa cgaatctctc ttttgcttct aagcatgaag
     7081 gttatatgca tgcatgtggt catgacggac atatggcgat gcttttaggg ttgactgact
     7141 ttataactaa acacattgag gatcttattt ataatgtagt actgatctat cagccatcag
     7201 aagaaatttc cggtggcgca caaagcgtta ttcagtcagg attgttggat aaatatgaag
     7261 tacaagcaat atttggcttt catctatggc ctggactagc taagggagaa gttttctctc
     7321 gaccaggacc tttgatggca caaagcagtg aaacagacat tatcattaaa ggccagtctg
     7381 cacatattgc ttctagtgaa aaaggaatcg atagtctgga ggcagctgta cgatttttga
     7441 agaatgttta tgattttgac cggcaattac cggcagagtg gaatcatcta atgaaatttg
     7501 gccaaatcca aggtggaacg atccgaaatg ttttagctgg agaagttatt gtatccggaa
     7561 gtatccgttc ttacagttca gatatgcaaa attatttgaa gaggggatta gaccatttag
     7621 cagaacagtt tcactctaca gctactattt cttttcgcta taatgacggc tatccagctg
     7681 taatcaacca tagaggctta tatgcagcac tgttagattc aaacaaacta catgaattag
     7741 atgctccagt tcttcaagcc gaagattttg gcatatatac gcaacaatat ccatgtgtat
     7801 ttttcttttt aggtgtcggt gatacccctg ctttacatga tccgacgttc gattttgata
     7861 tggatgtttt agaaaatggt gtagaatggt acaaaacgat tctttttaca gaaaatcttc
     7921 ttgtaaaaat cgatagcagt tcaaaagagg agcgagtaaa taatgatgaa tttatccaat
     7981 cgatttagtc ctaggctttc tagaatagaa gtatcaaaaa tacgacaatt cgatcagcaa
     8041 atatcgtcga taccagatgt gatcaaactc accctgggag aaccggattt tccaactcct
     8101 gaacatgtca agcaagcagg aatagcagcg attgaagaag acttttctca ctataccgga
     8161 atgagaggat tagaggaact gcgggaagcg gcttgtatat ttcagcaaca gcgttatgga
     8221 ttaacttatg atccgcaaac ggaagttttg acgacagttg gtgcaacgga agcgattgcc
     8281 tctgcgttgt tatctgtttt ggaagaagga gacaaggttc ttattccagc gcctgcttat
     8341 tcaggatatc agccattagt ggaactagct ggtgctgaat tgatcccgat agatacttct
     8401 gacacagggt ttgtctgtca gccggaacaa tttgaacgag catttgaaca atatggatca
     8461 gctgtcaaag cagtcatttt aaactatcct aacaatccta ctgggacgac attgtctgca
     8521 aaacaattga aagcaatcgc tgaggtttta aaaaaatatc cggtatttgt tataagtgat
     8581 gaagtatatg ctgaattgac ttatagtgga acgcatatgt ccatagctac ttatcttcca
     8641 gaacaaacaa tcgtgataag cgggttatcc aagtcacatg cgatgactgg ttggcgagtg
     8701 ggctttattt ttgctcaaaa agcccttatt gacgaactaa ttaaagtcca tcaatatctg
     8761 gtgactgccg ctacaacgat gtcgcaaaaa gctgcggctg aagcgctaat aaatggggtg
     8821 aaagatagcg agaatatgaa agagcaatat caaacacgaa gagactatct ggtccagcaa
     8881 ttggcgcctt taggatttga agtgacccag ccaaacggtg cattttactt gttttgcaaa
     8941 ctcccagctg ccattcaaac tgactcttgg cagttttgtg tagaattagc ggaacaggca
     9001 aaagttgcgt gtatcccagg aattgcattt ggcccagaag gagaaggtta tatccggatt
     9061 tcttatgcta gcagcatgga aaaattacat gaggcctgca aacggatcaa agacttttta
     9121 acagaacagt gattcataga ttttatcaaa aaaacaatcg ttaattttgc ggtatattct
     9181 gcaaggagac gattgttttt taaatttagt tcaaatgaac gcgtttcttt tgattcataa
     9241 ctaatgtaat gttaagttta aattgtttag aatgatttta aaagaatatt caaggaggtt
     9301 tcatcaatgg aaaaaatcaa agttgtcatt gtaggtgcat ctcatggagg gcatcaatcg
     9361 atcttggaac tattgacacg atacggtgaa aatgtagata tcacgctatt tgaagcagga
     9421 gactatattt ccttcatgtc atgtggtatg gagctgtatt tagaagacaa ggtaacagat
     9481 gtaaatgatg tacgtaattt cagaccagaa aactttccgc aatccaatgt tcatatttta
     9541 aataatcacg aagtaaaaac gatcgatgcc gataaaaaaa cagtaacggt tactagcgca
     9601 tcagataacg aaacaaaaga atatccttat gacaaattga ttttgagttc tggtgtcaaa
     9661 ccaaacaatc tgccagtacc aggagcagat ctagaaaatg tctacttgat gcgtggatac
     9721 aattgggcaa ccaaaatcaa agaaaaatta aatgatccgg ctattaaaaa aatcgctgtc
     9781 gtaggtgcgg gttacattgg gatcgaagca gcagaagcaa gccgaaaagc tgggaaagaa
     9841 gtcgtattgc ttgatgtgat cgatagacct ttaggcactt atttagatgc tgagatgaca
     9901 gatattttag aacaacacct aaatgaaaac ggtattgaag ttttgacaaa tgcaaaaatc
     9961 gaagctttta ctggtaacgg aaaagttgag gcaatcaaaa caagtgaaaa agaaatccca
    10021 gcagatctag tcattcaagc tgccggtgtg aaggcaaata cagaatggtt aaaagggatc
    10081 gtcgacttag atgaacgtgg ctggatccaa acaaatgaat acttgcaaac gaatcttcca
    10141 gatgtgtatg cagtaggaga tgctacactt gcttattcta tcccagcacg caaaaaaatg
    10201 ccgatcgctt tagcgactgt tgcacgtaga gaagcacgtt atgtagtaaa acatcttttt
    10261 gaagaagtac caaacaaacc gttcggcgga gtcgtaggtt cctctgcatt aagtgtcttt
    10321 gactatcatt ttgcagcaag cggattgaat agctttacag cagcaaaagc aggagtagat
    10381 gtacgagtgt cttattatga agatacgtta cgaccaaaat atgtaccaga agaacaagga
    10441 aatccaaaag tgtccatcca attattctcg gatccaatga cccatcaatt gctaggagga
    10501 gcagtattat ctacctatga tgttacaggt caaggaaatg tattggcact agcgatccaa
    10561 aacaaactga ctttagaaga actagcagaa gctgacttct tcttccagcc aggctttgac
    10621 cgacaatgga gcatgttgaa tctagccgct caacaagcgt taggagaaga accatttgta
    10681 gaataagaaa acgaaatatt tgaaaagagg ttgtgaaaaa gctgccttgc atcaagtaat
    10741 aagaacagcc aagtaaaaac agcttcttat gtttttaact tggctggact tattaccgca
    10801 gatgcaagct tttgaacacc gtttattttc aaaaaaggga ctgtgacacg atttgtgtac
    10861 cgacccccaa aagttagacc aaaaaatcta acttttggag gtcggtattt tttatggtta
    10921 aatatacttt tgaacttaaa ttaaagatcg ttcatgatta tttggatggc aaaggcgatt
    10981 ggaccgtaaa aatccagatc aagagattga agcggaaatg cttaaaattc gggagaagca
    11041 caaggattat ggctgtttac ggatgaccaa tgaactaaga aaccgcggtt tctctatcaa
    11101 taaaaagaaa gttcagcgct tgatcaagaa gctaggaata aaagtaacgg catacacgcg
    11161 taaatcacgt cgctacaatt cttatcgagg aaaagt
//
LOCUS       DAFKHN010000081        10936 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFKHN010000081 DAFKHN010000000
VERSION     DAFKHN010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.081"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..154
                     /locus_tag="LY912_002272"
     CDS             <1..154
                     /locus_tag="LY912_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBM6955927.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(235..1218)
                     /gene="istA"
                     /locus_tag="LY912_002273"
                     /pseudo
     CDS             complement(235..1218)
                     /gene="istA"
                     /locus_tag="LY912_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1613..2455)
                     /locus_tag="LY912_002274"
     CDS             complement(1613..2455)
                     /locus_tag="LY912_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBM6955928.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2780..3196
                     /locus_tag="LY912_002275"
     CDS             2780..3196
                     /locus_tag="LY912_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBM6955929.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3193..3663
                     /locus_tag="LY912_002276"
     CDS             3193..3663
                     /locus_tag="LY912_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6955930.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3677..4450
                     /locus_tag="LY912_002277"
     CDS             3677..4450
                     /locus_tag="LY912_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6955931.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4464..5276
                     /locus_tag="LY912_002278"
     CDS             4464..5276
                     /locus_tag="LY912_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBM6955932.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5330..6295
                     /locus_tag="LY912_002279"
     CDS             5330..6295
                     /locus_tag="LY912_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6955933.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6432..9155
                     /locus_tag="LY912_002280"
     CDS             6432..9155
                     /locus_tag="LY912_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBM6955934.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9168..9800
                     /locus_tag="LY912_002281"
     CDS             9168..9800
                     /locus_tag="LY912_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBM6955935.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10005..10232
                     /locus_tag="LY912_002282"
     CDS             10005..10232
                     /locus_tag="LY912_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HBM6955936.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10301..10567
                     /locus_tag="LY912_002283"
     CDS             10301..10567
                     /locus_tag="LY912_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBM6955937.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10557..10826
                     /locus_tag="LY912_002284"
     CDS             10557..10826
                     /locus_tag="LY912_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBM6955938.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3625 a         1742 c         2137 g         3432 t
ORIGIN      
        1 ttccttagaa aaattaggtt gtcaaaattt caactcacgt tctgttaaag ggctagagag
       61 tagatttgaa agcatattac tggcttacag tgttctatta agtcgagcac aacgacgttt
      121 tgaaggaact ttgagatatt ctttaggata ttaaaattaa ctagcaccac gggtaaaata
      181 aatagttttt ctatcaagta tattgaacta cgataaattt gttattttgt tttgtttaat
      241 ttcgttgtac ttattggctt tgacttcgat ttctttaaat actgggtaat cggtgtccgg
      301 caaagctagc aaatctgttt tttctgtgtt ccatagatca ttgataatga catgtttttc
      361 gtaatggatt cgctctcgat cgtgtgacag ctccaccgct aatgcctcgt tgaaactggc
      421 gaaatccttc ataatcggtg tagatgaaaa gaagttgtac cgtacatagc cgactttgtt
      481 ttccatacta cctttctcgt ttccgctacg tggattgcac acctgtgtct caaaaccata
      541 gtgcatagaa aatcggagga aaccgtcagt cagcaccgct tgttcagtct ttgtttttgt
      601 ctaagtaacg gccgttgaca tattatcaat ccgtattttc cgaggaacgc cacctgattg
      661 gctgaagagt tctttcatgc cttccaacaa acattcttga ttctcggcgg ggagtacaac
      721 ggcgaatcct gcattactaa aagggaaagt catcactaat accttcacat ctttaaacgc
      781 tccatcgtga caaacttcca tcgtaccaaa atcaagttgc gcttctgctg gcgggtgttc
      841 aagacgctca aagccttggt cttccagtgt ttccaagtag tgtgtcgctt tccaatcttg
      901 aatgaataca cagactgttc ggtaggatcc tggaaagcca tcggctttta aagcagtagt
      961 cattgcttca gcagtcctac gctttttatt tggcagctta gcatcttctg aaagccatag
     1021 ggaaacgatg cctccccact tttctgtata catcatacca gtctttttgc gtgctttagg
     1081 ttgcggcagc aaatcatcat ctgcatattt tttagccgtg cgccaattta catctagctc
     1141 ctttgcaata tgattaatgg atttatcatg attatttcgt aaatttctga tagtattaat
     1201 atcggtcatt gtgagcatac ctttcttacc tccagttaca gtgtcgagac tataacttta
     1261 gaggagtttc aggttgcccg caatggcttt ttatcttaac ttaatcgatt tgcggagttg
     1321 tgtagttttt cgttgcactt gtatgtactt ttattctgcc ataaacagct taatgaatgt
     1381 ccacttgaaa aagtgaataa acgaaataga tgactcgatt taataaggaa gtaaacccac
     1441 acagaaatat aggtgatttt ccttgaatga ccaagatatt gaaagttagt gaaaaaacac
     1501 aaaaaggtag ccctattcac agaaggtctg ccttttgtgt tatcgccagc aaacattaga
     1561 gggggtattt catatagctt ttgtcctctc gacagtccta tcagtttctc ttttaactta
     1621 tctctaagtg ctgtccagtt ttaatagctt ctagcttgtt tcctaactgt gtttttaata
     1681 tgttgaaggc ttttgaacct gtgcagtggc aagtaaggat tttttctact cgtgagtcat
     1741 tcaatttatt tccaattttc attacctctt gctcaggtag acctaaatta tttatataag
     1801 gtatgccaat catatggaag ccaccaatta ggtattttat gggtttagtc ggaaatgttt
     1861 caagagcaat ttccatcata tcgataatgc catgatgact acagccagta aagacaatca
     1921 gaccgtcttc ttgctcaatt acgaccaata attcatctga aaaatcatca taaacaaatt
     1981 tatcatccat ctttttgtat aaattcttgg tggtcgagtt tgctttgcct agggggatga
     2041 tatggaagct cggagcaagt tctgttttcg tttttattgt atgtaaattc tcatgcattt
     2101 taaggatttc atttttagga ataccaacat acagaaacgt ggttaaaatc tttaaataat
     2161 ggggtaaagt tacaccttca gctgtataaa taggggcgtt tcctgatttt aaatatctta
     2221 acccgccggt gtggtcagaa tgaccgtgtg aaataatcac tgcctccaga tcattcaaag
     2281 tttcccccat tttagtcgca ttatagacta attttttatt agcgccagca tcgaagagat
     2341 atttcttccc tgagtagtta attaagagag ataacccatg tccactttta aagttcaaat
     2401 ttattcttga gttttcaaat aaaaccttga tttccactat aacatctcct ttcacatgaa
     2461 cgtgtattca tatattgtag cacattaagt tctatttttt gttgtaatta ccgaaaaaaa
     2521 tattaatgga cgctttttac gctttatttc gtatgtggaa gaaaatttct taggatgtgg
     2581 cgggggattg gggcaaagct aaattccaat tacagtgatc atttaattag acacctttaa
     2641 atacccacac tttcatcaac actataattt agggaaagaa aagtgttggc atgatataga
     2701 aaaaccttta attaacagcg tttcctaaaa ttggcacgca tcttgcttat agaaaagcgt
     2761 aaggatagga ggaatgaaaa tggcaactat aattcttgcc agccatgggg aatttgctca
     2821 aggattaaag caaacagcga caatgattat tggagatagt gtaccaattc atgccttgtc
     2881 agcatttaga gatgaagatg aatctatttt ggtacaaata aaaaaacttt tagccacaat
     2941 agatatagaa gaaacctaca ttttaactga tattctaggt ggtagtgtga ataatgatat
     3001 gctcactatt attaaagagt atgagggatt gcaattaatt actggaatga acttaccttt
     3061 agttatttct attgcaacct ataatggaaa aattggggaa agtgagctag aaaagcttat
     3121 taaagagagt caacaatcag tgattgattg tagaaaatta ttagtagaac aacttactgg
     3181 aggagatgac ctatgattaa gttagtacgt attgaccatc gtttgttgca cggacaggta
     3241 gtattttctt ggagtaaatc attaaatatc aatcgtatta ttattgccaa taaagaggca
     3301 gcgaatgatg aattcaaaaa aatgtctttg aatttatcta aaccgactgg cattaaatta
     3361 acaatttttt cagttgaaca gttactagaa aaaatgccta aaatcgaaac acttaacgaa
     3421 aatatcatgc ttatttttgg taatacaaaa gaaattcgtc aattttgtga agcctatcct
     3481 aaagtacaag aaatcaacta tggagggata atcaaaaaag aaggttccaa gcaatttagt
     3541 aatgccattt tcttgaatga atctgagcaa gaagatgcca aaaaattaaa agctcttggc
     3601 attaaacaat ttattcaaca ggtaccaact tctaaaaaag aagatttgaa tacaatgtta
     3661 taaaggagga atgaaaatgc tcgttcagtc aattggttta gggttaatcg gtgttttttg
     3721 tattttagac tcaaggcttt taggaagaat gaattttgaa cgaccgttga ttgtcagtac
     3781 gcttgttggt ttggtacttg gagacatgga aaaaggatta attgttggag cctctttgga
     3841 attgatgtcc ttaggattag taaatatcgg agctgcttca ccacctgata tgaatatggc
     3901 atcaattatt gctacagcct ttgccatttt atcaaatgcg aatgcagaag cagcattaac
     3961 gattgccatt ccaatttcag tgttaggtca aatactaggt atcttaatgc ggacgatttt
     4021 gtcaaatttg actcacgttg cggatcgctt tatcgaacaa ggaaaattta gccaagcaag
     4081 gagaattcat atactttatg gctcgggatt atatgctctc atgtatttta ttcctatttt
     4141 tctagcaatt tattttggaa cgaatcttgt ttctcagatt gttgatgcga ttcctgagtg
     4201 gctaacaaat ggcttaacgg ttgcaagtaa aattttacca gcatatgggt ttgcgttgtt
     4261 attacaaacg atgttaacga aaaaaatggt gccattttta ttacttggat ttttaattac
     4321 tgcttattct ggattgggaa tcattggtat tgcagccttc gcatgtattg ttgcgtttgt
     4381 catggttcaa gttcaaggta aaaactcaaa tggtaaccaa aatgagccag atccattaga
     4441 tgacttataa ggaggtagat taagtgaaag agaaagatca aaatgcatgg aaatatcggc
     4501 agttcttatg gcgttcatgg gcaattcaag cctcatggaa ctatgaacga caaatgaaca
     4561 tgggttttat gtacggaatt gcaccaattc tagataacat ttacaagaat ccagaagatg
     4621 aagcaatgaa gaaagaagct tacgagcggc atatgatgta ctacaactgt acccctcaaa
     4681 caagtgcatt tgtgttaggg ttaactgctt ctatggagga gcaatactac gaagaccaag
     4741 aaaactttaa tccggaatca atcagtgcag tgaagacttc tctgatggga ccgctatctg
     4801 gtgttggtga ttctttcttt caaggaacga ttcgggtatt agcctttgga ctaggaatta
     4861 atttagccca acaaggtagt attttaggtc caattctagc aatgttaatt tcctttgtac
     4921 cttccttttt agttacttac tatggtggga aaattggcta taacatgggg aataaatact
     4981 tgtctaaact gtatcaagaa ggtttgatgg ataaagtaat gtatgtttgc tccattgtgg
     5041 ggttgatggt cattggttcg atgattgcca gcatgatcgg gattacaaca ccaattcaaa
     5101 tgggtaaagc ttttgtctta caagatgtat tagatagtat tatgccacaa tttttaccat
     5161 taggattaac cttcttcatg tactggttat tgcagaaaaa ggtcaaaaca ggatggatgt
     5221 tggcaatctg tttagtcgga ggaattattt ttagtttgtt aggtatctta caataaggga
     5281 ataaccaata aatttggttg aataatataa ataaggagga attcaattga tgaattcaaa
     5341 agaaattgtt aaagaaatcg tagcgaaaaa agaggtaaaa tcaatcgtat ttgttggctg
     5401 tggcgcttca aaagcggacc tttatcctgc aaagtatttt ctagaccaaa atgcgaagca
     5461 gttacggatt agtcattaca cagccagcga atttaactat gcaacaccag catctgtaga
     5521 tgagtcaact gtcgttattt cagcttcttt aggaggtacg actccagaaa cagttgaagc
     5581 taacgcagta gctaaagaaa aaggtgctac agttattagt ctaacacgaa gcattgactc
     5641 accgttaaca aaagatgcag attatgtaat ttatcatcga tttgcagaga actatgctgc
     5701 taaattagaa aaaacaggct actgtttaga attggcagta gaacttttac atcaagtaga
     5761 aggttatgac cattatgaag caatgcaaga aggatttgct actatctatg atcttgccca
     5821 aaaaagtgca gaatcagctc gtaaagatgc gaagaaattt gctgaacgct ttaaagatga
     5881 aaaagttatt tatgtaatga gtagtggtgc tacacatgaa gtagcatact caacatcaat
     5941 ttgcttgatg atggaaatgc aatggattaa ttctggtacc ttccattcag gagaattttt
     6001 ccacggacca ttcgaaattg tggataaaga cgtaccgttt atattattaa tgaatgatgg
     6061 aaaaactaga aatatagatg ctcgagcatt aactttcctt gaacgctttg atacgaaaac
     6121 agaagttgta gatgccttgg attatggctt gtcttcacat attgctaaag aagtcttaga
     6181 ctactttaac ccattcgtga ttactgcagt atttagagtt tatgcagaag aattgtcaga
     6241 agcaagagaa catccattaa ctaagagacg ttatatgtgg aaactaactt attaaaaaat
     6301 agatcaaact aaataaggtg gcttgagaaa ttaagccacc ttgttttctt caatgtgatt
     6361 ttatacatat ggtaaaataa ctagtacata tggtaaaata actagtacat attgtgaaag
     6421 caggtggcaa gatgcagcga ttaaatgact atctttatca actaacattg cttttgaaat
     6481 ctacgccttc agataattat tcagctcgca gtatttcgca agctctacag ttgaatagaa
     6541 gtacaatcag tagctactta aatgaaggtg ttcgtgaagg gcttttcata aaagtaaaaa
     6601 gttacccggt tttattttta catagaacag ctcttgaaga actacatatc acactgaata
     6661 actccgaaat agaatcaatt gaaagcttgt taacaatttc tcaaaaaccc gcattagatc
     6721 aagtaattgg ctctaaagga agtttgaaag aagcaattga tcaaattaaa acggcagtct
     6781 tatatcctgg aaaagggttg cctttattat tgatcggcgc tagtggatca gggaaaacct
     6841 ttctagcgaa taaaatatat gaatatgcag tagaagaaaa ggtcattcac acatcggcac
     6901 ctttcataga ttataattgt gcacaatatg tgagcaatcc agagttacta tcctctgctt
     6961 tatttggcta cacgaaagga gcatttaccg gagcaagcca ggagcatact ggtttgctag
     7021 aaaaagccga tggaggagta ttgtttttag atgaagtgca tcgcttatct gaagaagggc
     7081 aagagaaatt atttacattt atggatacgg gtgaattctc tcctatgggg gataatagta
     7141 ttcggaaaaa agccgatgtt cgattagtct ttgcaacaac agaaaatata tatacgactt
     7201 tcttaccaac ttttcttagg agattgccag ttattgttaa tctacctaga tttcaacaac
     7261 gtccgtcgtt tgaacgtctg tcattgattg atgaattttt tgtttctgag agccaaattt
     7321 tagctaagga actatctgtt tctgatgcat tgattcattt cttaatgaat agtgattttg
     7381 aaggtaacgt ggggaatatt aaaaatatta tcaagtatgc ttgcggaaac gcatatatcc
     7441 accagaagag tcagcaaaca attcaagtta aattattgga tatgccttta gagtacagtt
     7501 ataaattcaa ggagcaacta aataaaccca gaaagaaaag agcagatcga atctactatc
     7561 cagaagaaac acgacaagtg caactagaaa gaaacaatca gctttttgtt caattttttg
     7621 accaattact tactggattc tctgaagtga ttgaaaataa caaggatatt aaactatttt
     7681 tagaagaaat ggttaccaag gtaacacaag taatggatac gcttattttt caagaggatt
     7741 acgaaaaaga gcagtcttta tacgccattc taaactatca tattcgtcaa agtattgatt
     7801 ttatgcgaga aagctacggg tttgaacaag atggtaaccg ggtagtcgct ttggccaact
     7861 atctatatgt caaggataat caagtgattt ttgaaaatag tcttcaagaa aagaaaacca
     7921 aagatcagct taacgaattt tttgctaatg ttcttgaaac cccttattgg tatgcaaaaa
     7981 aaatcttaag ccttttatct gagtgtttag atcaacctgt gtatgaagag gacattttct
     8041 ttattacgct atatttttat agtttgaatg tcacgaatgt taaaacaggt attaagagta
     8101 ttgtgctagc tcatggttat tctacagcta gtagtatggc gaatgttgcc aaccgtatgc
     8161 tgaataagaa cgtttttcaa gcttatgata tgcctttaga tattacatta gagaaaattg
     8221 aagcaaaatt gattcaattc cttggagatt atcgaacaga ttcaggcttg attttattgg
     8281 tagatatggg ttcactaaac caactaggcg gtttattagt gaatcatcta aatggaccac
     8341 tgttaatcat tgatcatatc aatacaccgt tattattgga agtcggccaa caagtattaa
     8401 acaataaaag tatcaccgaa ataggagcag aaattgaaac aagtcttact ttcaaaaagc
     8461 agttactact tcccaagaaa aagaaaaaga aagccatcat tacttgttgt tatacaggga
     8521 ttggtagtgc gacccagatt caggagattt taacgaaatg cttgaaagat gcagttagag
     8581 aattagtaat tattccgtat gattacaaaa agctgttaga aaacaagaat tttgagactc
     8641 cttttcaatt atacgatgtc atcatgattg taggtacaga agatcccaaa attaatcaga
     8701 ttccatatat tggattagat cgcctgatta atgggggaag cattggcgaa tttgttcatt
     8761 acttggaaaa agagctgact attgaagtga acgatttaca aaaagaatta attttcaatt
     8821 tttcaattag taaaattgtc gaaaatttaa ccattttgga tccagataag gtgctatctt
     8881 ttgtacaaaa agcaattaaa gaattatcga agttattaaa ttttgatttt tctaataatc
     8941 agctgttttt gttgtacctt cactgtagtt gtatgattga acgaattgta cgtaaagaaa
     9001 gtgtggatga gcaagaggac attgaagaat atatgcaagc aaatggagaa ataatggata
     9061 aaattcatag cgcttttttt gagattgaaa gggaatacac aattgaaata ccagatttag
     9121 agttgcgatt attgagcgat attgttcaag gataggagtg aattcgaatg acaatgggag
     9181 taatttttga tatggatggg gtactcatag atagcgagac attttatttt gagagaagaa
     9241 tgaacttctt tcaagaactg gagatagatc caggatcaaa ccagattgat gattatgtgg
     9301 ggaaaacaga agctgcaata tgggaaacat tagttcctga ggacaaatca ttaagagagg
     9361 aactttatcc gaaatatgta gattatcgaa aaacgcatcc aattgatttc gctaaagctt
     9421 tacgaaaaga agtgaaaccg ttacttgact tcctcaagaa gcgggatata ccattggcac
     9481 tggcatcttc ttctccagct gtcgagatag agagtatgct cattcaatgt gaacttactg
     9541 aatatttttc ctttgttata agtggtgagt cattaaaaca aagcaaacca catcccgaaa
     9601 tatatttaaa agcgaaacag caattagact gtgacttctt tattgcagta gaggattcaa
     9661 cgattggtat taaatcagca aaggcagcaa atatctatac ggcggcacta aaacaaccaa
     9721 tgcaaatcga tcagagtgaa gcagacatac aaattgaaag tctacaagaa ctggaacaaa
     9781 ttgttttaga aaaaggttag tgaattaatg gaaataaggc tatatatctg tgctagctat
     9841 tttgactaac caaaaaaact tgctataatt caggtgtagt aaaaggtgct ggtaacacct
     9901 tttacgaaaa tgcttcggca gtgataatgg gattggcttt ttaagttttt tattttgttc
     9961 gcaatcccta aggtcatgtg aatgatccta gggattgcta gaatattttg caacagaacc
    10021 aaaatacgaa tagttatcaa gcagccatat tgactgcggt caatttagga ggggatactg
    10081 atactactgc tgccgtaact ggtgctcttg cgggtattct ttacgggggt gaagtgatcc
    10141 ctgaaaattg gagaaaatcg cttcaaaatg accagcttct taaaacgatc agtcagagat
    10201 tttgcgatac cgtgctatct caaagaattt gaataatgga tatgatgcaa atcttgtttg
    10261 tactaacgtt gtattgacaa aaaggatttt atttagtaca atgttagtac aaatgatgaa
    10321 cggaggtaga atcatgtctc aatcaaccat tacatttagg attcccgacg atgaaaaaga
    10381 actggtatta gaatatgcaa aagcacacaa ttcttcattg accgaacttt atcgaaatgc
    10441 tgtactggat aaaatcgaag atgaaatcga tctacggact ttacggagtg caattgaagt
    10501 ttccaaagag aaaaaagaga gtggtatttc tcaagaggaa atggagaaac tgctaaatga
    10561 attataaagt catctacatg ccgcaagccc agaagcaatt aaaaaaaatg gacagaaacc
    10621 aagctaaaat aattgtcgcc tggatcagaa agaatttaga aaacacgact gacccgcgtc
    10681 agcacggaaa aggtttgact ggaaataaga gtggggaatg gcgctatcga attggaaact
    10741 atcgaatatt ggctaatatt tgtgattctg aaattgaaat ccagatattc tcaattggac
    10801 atagaagtac aatatataaa agataaccgt ttttggaacg aagtagagtt tcgaaagtca
    10861 atgtataatc ttttgaattt tgcataatac cacaggtaga aactacccga tactatcggt
    10921 tggtttctgc tttttt
//
LOCUS       DAFKHN010000082        10689 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFKHN010000082 DAFKHN010000000
VERSION     DAFKHN010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.082"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            34..657
                     /locus_tag="LY912_002285"
     CDS             34..657
                     /locus_tag="LY912_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955939.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1148..2197
                     /locus_tag="LY912_002286"
     CDS             1148..2197
                     /locus_tag="LY912_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6955940.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2194..3075
                     /locus_tag="LY912_002287"
     CDS             2194..3075
                     /locus_tag="LY912_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6955941.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3078..3848
                     /locus_tag="LY912_002288"
     CDS             3078..3848
                     /locus_tag="LY912_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6955942.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4127..4981
                     /gene="aroE"
                     /locus_tag="LY912_002289"
     CDS             4127..4981
                     /gene="aroE"
                     /locus_tag="LY912_002289"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBM6955943.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5159..6322
                     /locus_tag="LY912_002290"
     CDS             5159..6322
                     /locus_tag="LY912_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBM6955944.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6439..6849
                     /locus_tag="LY912_002291"
     CDS             6439..6849
                     /locus_tag="LY912_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBM6955945.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            7023..9251
                     /gene="topB"
                     /locus_tag="LY912_002292"
     CDS             7023..9251
                     /gene="topB"
                     /locus_tag="LY912_002292"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBM6955946.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9422..9706
                     /locus_tag="LY912_002293"
     CDS             9422..9706
                     /locus_tag="LY912_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955947.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9866..10102
                     /locus_tag="LY912_002294"
     CDS             9866..10102
                     /locus_tag="LY912_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBM6955948.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10099..10498
                     /locus_tag="LY912_002295"
                     /pseudo
     CDS             10099..10498
                     /locus_tag="LY912_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
BASE COUNT         3734 a         1783 c         2259 g         2913 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattcta atctatgcta gacatgaaca ttgactgccg
     1021 catagattag aatctatgcg gttttttgtg taaagacaat gaccgctttg gccattgtct
     1081 ttttttgtag actggatact tgcctgatta taataaataa aaagattgac tttgcaggag
     1141 gaaaaaaatg aaaaacaaac gattaataac agttgtagta attattttag tttatttagc
     1201 aggtgcattt atttatggaa aagcctcagg cgaaaaagaa agtacttcga cgaaccagac
     1261 aaaaaaaaca acagttgttg gggtattgca atacgtgagc catccggcat tagatgagat
     1321 ttatcgagga atcaaagatg gtctgaaaga agaaggatta aaagaaggag aaaatcttga
     1381 gatcaaattt caaaatggac aagccgatca gagcaagcta gccacaatga gtcaacagct
     1441 agtacaatct gatccagatg ccttgattgg aatcgcaaca cctgccgctc aatcattagc
     1501 aaacacgact tcatcgatcc cagttgtgtt aggtgctgta acggatcctg tgggggctgg
     1561 attagtcgct tctttagaga aacctggtgg taatgtaaca ggtgtttctg atcagccgcc
     1621 tgttacttca caaatcaagc ttgcttctga tttgttgcca aatgcaaaaa aagtcggaat
     1681 cttgtatgct tcttcagagg ataattcaaa ataccaagta gcacaagcag aagaagctgc
     1741 aaaaaaagaa gggttagaat cagtaaaata tgcggtgcct tccactaatg agattgcaca
     1801 aacggttcaa gtgatgagcc gacaagtcga ttttatctat gttccattag ataataccat
     1861 tgccaatgcg atgcaaacag tggtaaaaga agcaaacaaa gcaaatatcc ccgtcattcc
     1921 atctgtggat acaatggtgg aacaaggtgg actagcaaca atcgggatca atcaatatca
     1981 attagggctt caaagcggta agatggcggc agaacttgcg agtggaaaag aaaaaccgga
     2041 aacgacgcct gtttatacat ttgatcaagg ggatacagtg atcaatcaat ctcaagctga
     2101 tcgcttagga atcattgttc cccaatcgat gaaggaaaaa gccaaaatca ttacagatga
     2161 ctcgcagcaa gaaacatcta aggaggatga caaatgatcg tatcagctat ttcacaaggc
     2221 atgctttggg caatattagg attagggatt ttcatgactt atcggatctt agactttcct
     2281 gatatgacga cagaagggtc cttcccatta ggtgctgctg tctgtgtgac agctattact
     2341 catggggtag cgccgattgt agctacatta ttaggcgtag gtgctggcat gatagcagga
     2401 ctcgttacgg ggttacttta tacaaaagga aagataccgg ttattttagc agggatttta
     2461 gtgatgtcag gattgaactc agttattttg tttgtgatgc gaacaccaaa tctttcttta
     2521 ttgaatcatc cgattctaca agacagcttc catcgctttg ggttacctga ttactttgac
     2581 acagtccttc ttggcttcat ctctttgggc atcttgattg ctgtactgct attcttcttc
     2641 aatacagatt tgggtcaagg ctatattgcg acaggagaca acgaaacgat ggctcggtcg
     2701 ttagggataa aaaccgatcg tatgaaaatt ttaggtttaa ctttgtcgaa cggtgtcatt
     2761 gcattatccg gtgcgctgat tgcccagaac gacggatatg cagatgtaaa taaagggatt
     2821 ggcgtaatcg tcatcggtct tgcttccatc atcatcggtg aagtgatctt ccaagaattg
     2881 acgctagcag aaagattgat tgctattgtt gtcggcagta tcatttatca gctattgatt
     2941 ttagtagtaa tcaaactagg gtttgacacg acttatctga agttgttctc cgctatcatc
     3001 ttagctattt gtctgatgat cccgcaattg aagaaagcac tgaacttaaa aacgggtttt
     3061 gagaaggagg catagtaatg actgatatat tgacaatcaa aaatggcaga aaagtcgtaa
     3121 acaatggaat gaatgaagag aaagtactat tggatgaaat taaccttaca atcagagaag
     3181 gggacttcat cactgtcctt ggcgggaatg gtgctggaaa aagcacactg ttcaatacga
     3241 tcgctggtac gcttcaactc agtcaaggat cgatctcttt taaagatcag ctgatcacaa
     3301 aagattcaga agaaaaaaga gcacgattcc tttctcgagt tttccaagac cccaagatgg
     3361 gaacggctcc tcggatgaca gtagcagaaa atttgctact tgcacaaaaa agaggtcaaa
     3421 aacggaaatt ccgtttacgt aacttgaaaa atcaaaaaga agattttttc agactatgtc
     3481 aagaagtcgg taatggccta gagcaacact tggatactcc agcgggtgaa ttatctggtg
     3541 gtcaacgcca agcattaagc ttgctgatgg cgacgatcac agctcctgag ttactattat
     3601 tagatgaaca tactgcagct ttagatccta aaacagctaa agcattaatg cgattaacaa
     3661 atcagcggat caatgaacaa aaattgactt gtctcatgat cacgcatcga atggaagacg
     3721 ccttgaaata cggaaatcgt ctgatcgtac tccaaaaagg gaaaatcgtt caagatattt
     3781 ctgaaaaaga aaagcaacat ttgacaatgg gcgacctttt gcagttcttt gaagaagtag
     3841 tggattgatt tcgacagaaa aattcctttc agtagaagga cttgaaaact cattgacatc
     3901 ttcctttgat tcatcctata cttaaaacaa taaacaatta aacatatttg ggtgttttgt
     3961 aggatcacgt agtcaatgat tttaacaatt aaatagaata ttctttgctc tgacaagtaa
     4021 acgatgagaa aagaatttgc tactttgcca cctagacgtt tcgtactttt tcgtatcaaa
     4081 cgctaagtgg ctttttttat tgaagtaaga acaaaggagg aataagatga tttctggaca
     4141 aaccaaatta gctgggctct ttgctgatcc ggcttctcac agtttatccc cattgatgca
     4201 caatactgct tttgaagcaa acaacatcga tgcggtgtat ttagctttcc aagtaaatcc
     4261 aatgaatttg aagcaagcag tcgaaagtat tcgaactttt gatatgttag gtgtaaatct
     4321 ttcgatgccg aataaaacag cggttattcc ttatctggat gaggtaagcc aggaagcgca
     4381 attgatcgga gcagtgaata cgatcgtgca cgaaaagggt cgtttgattg gctataatac
     4441 cgatggtgcg ggcttcatgc aatccgtgca agaagctggg atttcgatca aaaagaaaaa
     4501 aatgactcta ctgggagctg gaggtgcagc aaaggcagtc actgttcaag ctgcgttaga
     4561 cggcgctgag gaaatcgtag tttataaacg aaacaaccaa acattcgctc aagtaaaaga
     4621 aacattcgaa caactcagct atcgaacttc ttgtaagata aaagttcgtg actttgccga
     4681 tacgcatcaa ttaagaaaag acttgaaaga aagctgtctt ctagtcaatg caacagatat
     4741 cgggatggga aagaaaatca atcagtcacc gctcttagat ataagcatga tgcatgagaa
     4801 tctagcggtt tttgatttga tttatgcacc tagagaaaca cgtttattaa aagaagcaaa
     4861 aaaagtagga gcaaaaggat acaatggact tggcatgttg atctaccaag gagcaatcgc
     4921 gtttgaatta tggacaaagg aaaagatgcc gatccatgtg attgaaaagc tgtttgatta
     4981 aaaaaggata atagataaag atcttttatt ctcgcataaa cggtctcaag aaaagtaatc
     5041 ctttatgtat cgaagcattt atttcgttat tttttattaa attatcaaaa aatgataggc
     5101 ttttgtcgat tggttatcgt atcctttatt tatcagtaag aaacgaggag gaaccacaat
     5161 gagtcggatg gatcgctata aggacatcca taagaaggcg aaacctctga agcgggatac
     5221 ggggagtatt tttgctagaa gagaacgaaa acgaacgcgt atggaaaatg aggaagatgc
     5281 tacccgtatt tatgaaagag agcagcattc atttgaacat ttgaaccaat acgagcaaca
     5341 gatatacaga gatgcaccaa gagcagaaga acaacaaaaa aataaaaaat ttttcaatcg
     5401 gcaaaagaag aacaaaccgt taaaacctcg aagaaagcga tcgtggaaaa aaatcattct
     5461 atcgattttg cttgttttga tcctttattc aggtatctca ttttttattg gtaaatatgt
     5521 agctgaacat gacacaagct tagaggcagc gacttcagaa acctttcatg ggcaaaaagc
     5581 gacgaatggt gcgcataata ttttgatcct tggaagtgat acacgcggag aagatgccgg
     5641 gcgagccgat acgatcatgg tcttacagtt ggatggtcct tcccataagc cgaaactgat
     5701 ttcttttatg cgtgacagct tcgttacgat cccaggggta ggacaaaata agatcaattc
     5761 agcttatgca tacggaggag ccgatctagt gcgtcaaact ttagtagaaa attttggaat
     5821 cgattgtcaa tactatgcga aagtcgattt caaatcgttt gaaaaagtga tcgatgcctt
     5881 attcatgaac ggagtgaaga tcgatgcaga aaaagatctg aatctggatg gtgtagatat
     5941 taaaaaaggg gtccagaaga tggatggaca tgttcttttg cagtacgcac gtttccgaat
     6001 ggatgaacaa ggagactttg gccgtgtcag acgccaacag caagtaatga acgctatttt
     6061 cagccaattg aagaatccat tgaatctgat ccgtgcacct tatgcagctg gtaaagcttt
     6121 aggatataca tccacagatg tcactgcttg gttcttgacg aaaaacctct tttcgattgc
     6181 acgaggagct ggtggcattg atcgaataag tgtgccagta gacggttcgt ggaattatgg
     6241 gcaaagtgat tatgctggca gtattcttga aattgataat caaatgaatc aatctgctat
     6301 tacagatttt ttgaataaat gatcataaaa aagatcaaga agaagctgcg caaggctttt
     6361 gtcatgaatc aatcaaacga ttcactcgta aaaaacgctt tcttatggta gatttaacca
     6421 agagaggagc tgtttacatt ggatatctat ctgaacttca aaaatgagtc gcgtgaagcc
     6481 atcgcttttt atgaaaaagt ttttcagact gaagcatcag gtatcaccac atacggtgaa
     6541 atgcctggaa tagaacaaat gaacttgcca gaagaagcaa aaaatctaat cacgaatgca
     6601 cggctgaaca tttatgatac attagttatg tttgcagata cgccagaagg aattggtcct
     6661 gaattagttg tgggaaataa tgtttcttta gtcatccaga caagaaatga agaagaaacg
     6721 aagcgcctat ttgaaagctt agctgagggt ggtaagattg agatgccact ggatgctgtt
     6781 ccgtgggctc agttgtatgg gatggtaact gatcgatttg gcatcaactg gcagattaac
     6841 caagagtgac agctaaagat gaatattttc tggaaacatc aagcagcaaa cggatcatcg
     6901 tttgtttgct tgatgttttt gtgtctattt cgactatacg gtatcttttt tttattgcca
     6961 gatgcgaaaa tatgttccat aatagagaag tccgcaaaaa attaagtaac ggaggtcaga
     7021 agatgaagac ggtgatacta gctgaaaaac cttcacaagc aaaagcctat gccgaaacct
     7081 tccaacagca aaagcggcat gaagggtatt atgaaatcag cgatccattg tttgctggtg
     7141 aagtaaccat cacttatggt tttggacatt tggtagatat ggttgctcca ggagcttatg
     7201 aagagcgttg ggcaaaatgg tctttagaaa atttgcctat tttcccagaa accttccgtt
     7261 acgaagttcc aatggacaaa cgtgcacaat tttcgatcgt aaaacgagaa ttgcagtcag
     7321 ccgataccat cattattgca acagatggtg atcgagaagg tgaagccatc gcgtggtcga
     7381 ttattcgaca agcaaacgca ttttctaagg aaaagaacta tttacgttta tggatcaatt
     7441 ctcttgaaaa agaagcaatc tatgaaggtt ttaagaatct ccaacctgga aagaactatt
     7501 ttccaaaata taaagaagcg caagcaaggc agaacgctga ttggctgatt ggaatgaatg
     7561 gaagtccatt atatagcttg ctacttcaac gaaaagggat tgatggcagt ttttctcttg
     7621 gtcgtgtaca aacaccgaca ctctatatga tttatcagct gcaagaagaa atcaaacact
     7681 tcaaaaaaga aacgtacttt gaaggagaag gtttaattac gacaaacaaa gggcagtttt
     7741 ctggaaaaat cgtaccaaaa aaagcattta aaacccaaga agagttaacg aaggaaatag
     7801 aaaaacttgg agcgcattta ggtaagcaaa acggacggat tcttgaagtt acgaaaaagg
     7861 aaaagaggtt gcatagtcca cgtttatttt cgctatctag tttgcagaca aagatgaatc
     7921 agctaatgaa agcaagtgcc aaagctacac ttgatgctgc tcaaggattg tacgaaagca
     7981 agtttctaag ctatccaaga acggattcct tttacattac agaaaatgag catcagtatc
     8041 tggttaaaca tctgcaaaat tataaaaaat ttttaggaat agaagaagta cagacaactg
     8101 agatcaaagc aaagaaacga tatgtcgatg cgaaaaaagt tcaagaacat catgcaatta
     8161 ttccgacaaa gacgattccg actcctgcac gctttgcgaa gctttccaaa ttacagcaag
     8221 caatctattt gcaagttttg cgcactactg tggctatgtt tgctgcagat tatatctacg
     8281 aagagacgac cgtaatgacg ggcgtacagc aattaaagct aaaaagcatc ggaaagatcc
     8341 cattacagca aggttggcag gaaatcttac gcatcaagtc aaaaaagaaa gaagctcaga
     8401 ctcttcctcc tatcgtagaa aatgaagaag cagaagtaga actgaaaagt atggagaaag
     8461 aaacacaacc tccaaaaccc tataccgaag gaacgttgat cacagcaatg aaaactgcgg
     8521 gaaaaacgct ggataatgat gaagcgcaag aaattctcaa agaagtagaa ggaataggga
     8581 cagaagctac acgagccaat atcattgaaa atcttaagca gaagcattac atcgaagtca
     8641 ataaaaacga aataactgtt acgccaaaag gaatcactct ttgtaaggca gtagccaatg
     8701 aaccattact gacgagcgca gaaatgactg cgcgctggga agggtacttg agaaaaattg
     8761 gtaaacaaga ggggacacca tctgtttttt tagagaatat caaaaaattc atcctacatt
     8821 tattggcaga agttcctaat caaatcgaca aggtagactt ttcagatgag attagcggga
     8881 cacgtcagat aaaagcgatg gagaagaaaa acgatcaatt aggaagatgt ccaaaatgta
     8941 aaaagggaat agtcatgctt tatcctaaaa tcgctacatg cttgaatccg gaatgcgact
     9001 tcaaattgtg gccaacagta gctaaaaaga agctgactaa aacgaatctc agagatttgc
     9061 tttcaaaagg aaagacaagt aaagttgtca aaggttttac tggtaaaaaa gggaaattcg
     9121 atgcagtttt agtattaaaa gaagatatga caatcggttt ttcttttcca tggatcgaaa
     9181 acagtggaac aaaagcagtt gatggaaaca aagaaacatc aagaaaaaat aatgaaaacg
     9241 aagtagagta aatgaaaaca atgaaatagc ggaatattta ttccgaaaag tgagaatata
     9301 aataccaata aaactaaaaa atatcagtga atcaagcaaa aacgttgggg taggctgatt
     9361 ttatatagat agcaaggagt ttttttattt gaaaaaagtg cattcatttt taaattatct
     9421 tatgggagca atcacgattg tggctgtgta ccaagcattt ctaaagtatc ctgattacgg
     9481 gacgaagttg ttgtcattga cgcacaatca aacagcatat tcaccaacgt tgattttatc
     9541 gactttgact gcaggagcta aaagcgctac ttattttttt cataaaacga caagcatgct
     9601 aaagcgaaag aaacagcgaa aacaattgtt ggtggtggta gcggctatga tcattattta
     9661 ttttctacca gttattacac aagtatttca tcaatatttt ggttaagaat acgagagttt
     9721 gtgacaaaag tcatgtcaca aacttttttc tttgtcattt tttcgtaaga aaaagcaaaa
     9781 taaaagtata tacattgatt aaaagtatat acttggatat aatgtactta ctatagaatg
     9841 agaatggtat agagggtggc gaaatatgaa aaaaatgaaa aagtataaaa ttagaaaatc
     9901 tggcaatagc gatgtaacaa ctatcccacc agaagtaaaa gaattcatgg gtgtgcagac
     9961 aggtgacgca atcagttatg tttttcaatc tgatggttct gtacgaatga tcaaagcaca
    10021 agaagaacct gatattgatt cattagttga ttcgatcatg aatcaatatg aagacgcgtt
    10081 aaaagatttg gttgatttat gaggtatctt tcgactaaag aaattatcaa aatcaacgcg
    10141 aaagttattt taccgtcact cgccaggcga aatgatcggt gtaaaagatg caaatgcatt
    10201 agatatggcc gtcaaacagc cttcacaagc agtattcaat caagaactct atcctgaaat
    10261 ctatgaaaaa gcggcgattt tagcaattaa tttagctaaa aaacatcctt ttcataatgg
    10321 caataaacga actgctcttg ttgccatgtt gttgtttctt caattgaata attgtccagt
    10381 tgctttttct cgtcaagaag ctgttgattt tatcataatg attaccacta gttcattgga
    10441 tttcgattca ctaaagtcca agataaccag ttatttacga caaaccgcaa taaaatgaac
    10501 gaattaaaaa ctttatttct caattagatc agcatgtcat taaggaatat gctgattttt
    10561 ttatgtttaa tcatacaaaa tagttttttc ataaaaatat ggaaaatatg gattaatttt
    10621 gaaataattg atttaaaagg aatacaaaag agtgaatagt aggaaatagt ggtttagaac
    10681 tagtgggct
//
LOCUS       DAFKHN010000083        10579 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFKHN010000083 DAFKHN010000000
VERSION     DAFKHN010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.083"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..162
                     /locus_tag="LY912_002296"
     CDS             <1..162
                     /locus_tag="LY912_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBM6955949.1"
                     /translation="KFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEENRK
                     KAMRKRVSR"
     gene            complement(224..2035)
                     /locus_tag="LY912_002297"
     CDS             complement(224..2035)
                     /locus_tag="LY912_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBM6955950.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(2032..2397)
                     /locus_tag="LY912_002298"
     CDS             complement(2032..2397)
                     /locus_tag="LY912_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBM6955951.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(2560..2955)
                     /locus_tag="LY912_002299"
     CDS             complement(2560..2955)
                     /locus_tag="LY912_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBM6955952.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(2973..3935)
                     /locus_tag="LY912_002300"
     CDS             complement(2973..3935)
                     /locus_tag="LY912_002300"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBM6955953.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(3935..4147)
                     /locus_tag="LY912_002301"
     CDS             complement(3935..4147)
                     /locus_tag="LY912_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBM6955954.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(4168..4866)
                     /locus_tag="LY912_002302"
     CDS             complement(4168..4866)
                     /locus_tag="LY912_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBM6955955.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(4886..5428)
                     /locus_tag="LY912_002303"
     CDS             complement(4886..5428)
                     /locus_tag="LY912_002303"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBM6955956.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(5560..6564)
                     /locus_tag="LY912_002304"
     CDS             complement(5560..6564)
                     /locus_tag="LY912_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBM6955957.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(6561..7550)
                     /locus_tag="LY912_002305"
     CDS             complement(6561..7550)
                     /locus_tag="LY912_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBM6955958.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(7547..8353)
                     /locus_tag="LY912_002306"
     CDS             complement(7547..8353)
                     /locus_tag="LY912_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6955959.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8519..9475
                     /locus_tag="LY912_002307"
     CDS             8519..9475
                     /locus_tag="LY912_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBM6955960.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(9552..10070)
                     /locus_tag="LY912_002308"
     CDS             complement(9552..10070)
                     /locus_tag="LY912_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBM6955961.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(10158..10307)
                     /gene="rpmG"
                     /locus_tag="LY912_002309"
     CDS             complement(10158..10307)
                     /gene="rpmG"
                     /locus_tag="LY912_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBM6955962.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
BASE COUNT         3290 a         2309 c         1810 g         3170 t
ORIGIN      
        1 aaatttgtat ctggaatatt agtaggaagt ctggcaacag ccgctgccgt tgctggtttg
       61 gtcgcttctg tgaaaaaaac agtgatcgat ccaattgacg aaaaagaagc aatgatcgaa
      121 gaaaaccgta aaaaagcaat gcgcaaacgc gtttctcgtt aataattatt taaaaacacg
      181 catgaagact tgtgaaagaa cagataagtc atcatgcgta tttttatttg tcagtcaata
      241 taagttgtgc tattttatct gcctgtctca gattccatgg atctgtataa ggtctagcta
      301 ctgctgcagt tagccaatcc acaccttcaa caggtattcc atagcaataa aagtcagact
      361 ggatttcccc tgaagcatca atcacgcgat tcgtacctcg ctcaacatct atagcttctg
      421 aatgataact tcctgtatta tctgaaaatg aaaaagggcg aacaagtttg ttttccttca
      481 aattttttat gacaggatta cttgaacgag aaaagcttgt ttgtggcaat cgagcttcaa
      541 tcaaatagcg actgctgatt tctttatctt gtagagaaat aacatagcgg ttgtgctttt
      601 gctgaatatc aaatggcggt tcgaacaaat gaaaaatacc cgcatctatc agtgctgcta
      661 attctttcgt ccgaatgact ggcggaccga tcgttaaaaa gctatttaga tgagtaaacc
      721 atccccatag tatttctttg tattcctttg cagaaaaaac gtgccattca atagcctgcc
      781 ggattggatc acgccagtct tttaatgcat caaatgttga agcaaatgct cctgtgcaat
      841 tgcctttttc cgcttctttt atctgccctt caataaatgc tcggctagct tctgcaaagg
      901 actcatcctg ataggtaaga ggaatttcta aatacgacca atcccatcta taagggatta
      961 gtgctggatg ctttccgaga cactcctctg aagagaggga gagaaaatca tgctcaaaat
     1021 ttttctttgg aatcggcaaa tgatattctt cgatgatttt cttgtaataa aacaactcaa
     1081 cgtctttttt cagatagtca aaaaatgttt cgccagtcaa aaatcccgac tgatgccatt
     1141 gctccaggtt ttcttttgtt agtaaccgtg gccatgccat tgatccgcct tgcttttggt
     1201 ttcttcctcg agggtaataa gggagccccc ttcttgatcc actgtataca atcggttcct
     1261 tgcctgatgg atgatagaca agttttcctt tttcgttctc gaagcgccct tctcttgata
     1321 ctgtaaacaa tccgacataa tcaaaaaaac ttaagcctag acctcttaaa aagacatttt
     1381 ctttaggcgg tatcttcgaa agatcgacat ctgcaggatt agaaggaagc tgatacagta
     1441 aatcattttt ctttgcgtag tctacccaca ctctttcttc ttctgtctca tcattttccc
     1501 agtgaccgct tgctaaaaca agctgatcga tagaatagct ttgctgatct gtctgtaaaa
     1561 gataaccatc ttttcttttg ctgacttttt ttactaaaga ataaacaaac tgaatagaag
     1621 ctggaaattc ttcttgcaac tttgagaaaa accagcgttg atagagtccg tataaacatc
     1681 gagtagattg ctgatctttt tccagacgat tgatttcttc tataattagt tgcttatttt
     1741 tggttaccgt ctgttcgata taatctgtag caggtccttt actccattga aacaagttgg
     1801 gtccctgtgt taccaatcct ccactggaca atgtttcatc tgtaaaaagc gtcacttgtt
     1861 gagaaacaga attcattaat aactccggtg gctgattcaa ccgccaaact cgacctccag
     1921 gaccattggg atcgaaaaga aaaagttcaa gagaatgtct gtcctgatta ttatggagaa
     1981 tcctttctgc tatacttaat cctctaggtc cggcaccaat gatccctatt ttcatttgca
     2041 tgcctccatt tcgataaatt ttttcaataa aacagcatgg ttctgatgtt cattttttgc
     2101 accataaaca aaagtaatga ctggatgttc tttcataagt tgactgagtt taaaaatagc
     2161 ttgcttcttt tcttcttcga aaatcaattc ttgctggtat ttctttgcaa atgaagcaaa
     2221 tcgttctggt acatggtcaa aagttttgcg tgcttcatta ctaggtgcaa tttctttcaa
     2281 ccacagatct aactgcgctt tttcttttga aattcctcgt ggccagaacc tatccacgag
     2341 tattctatag ccatcctctt tttcagcatc aaggtaaaca cgttttaatt tgatcatagt
     2401 tgtttccttc tttctgcctt ttcgcttagc ttatatatgt agataatagc acaaaataaa
     2461 aaaaatgaac ggcacaacta tccattgcgc cgttcatgtg atcttggtca aaatctaatg
     2521 attgattcgg tttttaaagc tgtcatacaa tcatctgttt tatacttttt tacttttgat
     2581 ttttccagac catccgtcat atccaccctt aagtaaataa atctcttgat aacctgcttt
     2641 acgtaattta tttgctgtac ggatgctcaa gcttttcttt tgatcgtaaa tatagacagg
     2701 ctggtctttt cgaatagatc ctaatgaatc tttcaaaaca gtgtaaggga tgtttcttgc
     2761 acctaaaata tgcccagcat caaacacatc tttttcgcga acatcgatta cttgtgcttt
     2821 tctcattcct tctcgaaatt cttcttctgt caaagtcgtt gctgaacgct tggccattac
     2881 tcgtagatag acttcccaaa agatgattgc aagcacaatc aatagcaaaa tgatattaat
     2941 tacccataaa accatgtaat gcctccgttt ttttaagcaa atttcaaggc taatgaggca
     3001 gcaccaatga caccagcttc attaccaagc tctgctaatt tgatttttgt tgattctctt
     3061 acttgcggga aagtaaattc tttaaaatat ttctctacac ggctacgtaa aaattctcct
     3121 gctgccgata ctcctccacc taacacaata cttgacggat tcaatgtatt ccccaagttg
     3181 gcgcaagcta aacctaagta gaagcatacg cgatcaacaa ccatcaatgc aaacggatcg
     3241 tcttcttgag ccatttcaaa gatatcttta cttgttactt cttcaccgtt gtctaacatt
     3301 gctttcagtt ttgaatctcc tgcgtattct tctgccaagt aacgacctag acgtaccaca
     3361 ccagtagcgc tagacacagt ttctaaacat ccgcgtttac cgcaagtaca ttcgaaccct
     3421 tcaggatcca cagtgatatg gccgatctct ccgcctgctc cgctcacgcc gtgaatcaaa
     3481 tttccgccag caacgatacc accgccaaca cctgttccta gagtaacgaa tacaacgtct
     3541 ggatcgtttt ctccagcacc tttccatcgt tcacctaaag cagcaacatt cgcatcatta
     3601 tcgatagcga atttgattcc tgttcctgcc tcgatcagtt ttttcacaaa ttgaacttct
     3661 gtccagttta agttatacgc accaataacc gttccagctt cgctgtccac gcttcctggg
     3721 gtacccatgc cgattccgat aaagtcttcg gctttcatat tatataaatt caaacgatgg
     3781 ttgattgatt caatgatttc aggaacgata tgcttaccat catccaaaat attggtatcg
     3841 atgctccatt tttgttgaat ctctccttct ggtgttaaaa ttgcaaattt tgctgttgtt
     3901 ccacctaaat caatcccaat aatcttcttg tccattacaa atttcctttc tttcggcttt
     3961 cttcaattcg gtgctctctt tttaatatgc gccacgctgt catgtatgta tcatgatcaa
     4021 tcaaacggct atcatacaga ttacgcaatt cgatagtcat taattcaatg tcatagatgc
     4081 gtgcacccac atagataaag atgccaaatt ttttgaacag ctgctgtaca tcatataagc
     4141 tctccatctt taagcacttc cttcatatta tacaagtaaa ccatattttt ttaaacccag
     4201 taaaatacat attacaaaaa gaaatacaaa aactagtgta gaaagaatcc tttggtgtat
     4261 cgaatagctt gtctgttgtt tcggtagacc caaaacattc cctaacacta atccgccaat
     4321 tagcccaccg acatgtcccc aaacatctac agaggtatcc agaagaccaa aaacaaatgt
     4381 caacacaata aataaaagaa aatgtctgac tagctgctgg atcgctgggt tatgtttaaa
     4441 atgaaaccct aagataaaca acgcaccgaa caaaccgaat atcgaagtac tcgcaccacc
     4501 agacagaaca ttcgcttcgt taaaagcaaa gcttgctgta tttcccatta tcccgctgaa
     4561 catataaatc aagaaaaaac gccaatggcc atagattgcc tcgatttgct gccccataaa
     4621 atacagtatc agtgagttca ttacgaaatg catcagtcca aaatggatga agattggtgt
     4681 cactaaacgc caccattcat tgaagtgaac aagataagga ccatacattc cggcataata
     4741 agggatctca agtcgcggaa ataattccat catgaggaag accgctgtct gtatccctaa
     4801 aaaagcatag gtccataacg gtcgtcttaa ccatgcacgc aattttattt gctgttgata
     4861 attcatgaaa acctcccatt tcattttagt caataaacaa ttgttggatc ttctgatcaa
     4921 agctctccgg ttgccattgt tcattcaatt gttcacgaaa aacaaggcta catgtttttt
     4981 tatgaaaatt atttaaatac cggtcgtaat aaccaccgcc aaaaccgatt cgataaccgg
     5041 ctctattgta gataatacct ggtacaatga ggagatcgat catctccggc aaatagagct
     5101 tctctgattg tggctcaaga acaccaaaac tcgaacgtac aagaacggac tgttcatcca
     5161 tttcataaaa cgccatctga cgtttcggca aagttttagg tacaactatt ttcttttgtt
     5221 ctttttctgc tcgttggata accggctgtg tatccagttc aaattcattc gataaagtcg
     5281 tccctatcac ttttgctgac ttccagtact cgctggcgaa tagctgttta tagattcgct
     5341 gttctttttc ctttttcttg ccacttttgg ccagattttt cagcttttcg attcctttcc
     5401 ggcgtaatct tactttcaat tggtccaaaa actcaccctt ccttctctca taaaatggta
     5461 taggaaaaaa agaaaaatag caatcgaact ttcaaataaa tgcataaata gaataaaaag
     5521 aagacctaga aatgattggc cttccttttt taataaattt caactgttca gcgcgtgttt
     5581 ttgtctgata aaaagtgcat acagaaaata tggcgcacca aaaagggcaa tcaaaattcc
     5641 tgtaggtact tccccacttg gtagaatcac tctagcaacc atatctgcac taagcagaaa
     5701 aatggaaccg aacaaaccgc tcagaacaaa ggtccagtta ttttctttac gtacgactag
     5761 cttcgcagca tgaggagcta gtagtcctac aaaagataaa ctacctgtca ccgctacact
     5821 accgcttgcc aaagcaacag ctaacaacaa aaggattttt tgacttttag ccacgttaag
     5881 gcctaatcct tgcgcgcgtt cttgaccaaa tgatagcaat ccaatcctct gtgcataaag
     5941 tcctcctagc ggaattaaga taaccgccca tggaagcaat gcccaaacat aaggccagct
     6001 cgcaccccag attgatcccg ctaaccatgc attcacaaat ccataatttt ccttagataa
     6061 ttggatcgtg catagcaatg ttaatgcaga aaggccggca ttaacggcaa taccggacaa
     6121 taagattcga ttcataccca aaaagccatt tcgatcatag gccgcaagat agacacagca
     6181 agcagctaaa acaccaccta gaaaggctac aactagcaat agaaacggca gcgaatagtg
     6241 cgaaaagaaa cctaaataaa gcatcactaa aaatcctgct ccggcattaa tgcccaatat
     6301 actagaatct gccaattcat ttcttgttac tccttgcaag atataaccag aaacgccaag
     6361 acaagctcct gctaataaac tgatcagtaa tcgaggaact cgaaattctc taacaatcag
     6421 cgccaaagaa gatgattctt tccctatgaa cgtggcaaaa agctgatcca ggtaaataaa
     6481 aggcgtacca atcattaaac tacctataga caggatgaca agtacaaaaa gcaagaaata
     6541 gaacgtccaa tatatttttt tcaccgttgt tccctcctta cttgtatcag taaaaacgga
     6601 acgccaatca atgcaatgac taatccaaaa ggtgtttcaa aagggggatt gatcatcctc
     6661 gctgtaaaat ccgccaacat aaccaatcca ccgccaacta aaaaagagac aggtagaaca
     6721 taacgatagt ccgttccaac cattccgcga acaactggcg gaaccaacag cccaataaat
     6781 gaaacaggtc cgactaacga aacggcaatg gctgctaaca ctgcaactag acagaaaaca
     6841 atcaaccgcg ttcgtttagg atgacttcca agagctaatg catgtgtttc actcaaatga
     6901 atcaaagata ttgcttttcc taatgaaaaa gaaaccaaaa cagcaagtat atataaagga
     6961 aacaatactg ctaattgttt ccatgtgata ttggcagctc cgcctacaaa ccaaaaagca
     7021 agatcctgct gcagattaaa gaattgggta agtgcttggc tgatagcagt aaaaaaagaa
     7081 ctaatagcta cgccagctaa aatcagctgt aaaggattca tgcccatttt cgaaaactgc
     7141 aaaaaaccaa atacgagcaa agttacagca aaagaacctg ccaatgacat tagaaacaca
     7201 gaaaaatcag aagctttagg ccaaaaagca aaactaaggg ccattgccaa cgaagcaccc
     7261 gcgttgattc ctagtaagcc tgaatctgct aaaggatttc ttgtcactcc ttgcatcaat
     7321 gcaccgctca atgcaaaaca actccctaca agaaatgctc ccgccacacg aggcaaacga
     7381 atatttcgta tgatttggtg actttgtttt gatctatcaa aatcaaacaa cgcctgccaa
     7441 aaatctgctt ttcccacagt cgctgcgcca tttgaaagag caacaaaaaa aataatcaaa
     7501 agaacaaaac agaccaaaag caggagtcta tttttcttca tagtcctcat aattgatcct
     7561 cctgctcttt tggcaacaaa tcataggtta gaaaaactgg tttatttgtt cttggaagcg
     7621 tgacaatcgt tgcatcaatc tcaaatattt ttttcataca ctcttttgtg atcacttctt
     7681 caggtgtacc ttctgtgatc aacttaccgt ttttcattgc taataaataa tctgaaaaac
     7741 gtgaagcatg attaatgtca tgaatcgaca tcaagatcgt tgtttgtttc atttgattga
     7801 tttcagtcaa taactgtagg atctctaatt ggtgtgccgg atctaaaaat gttgtcggtt
     7861 catccaagat caagatatct gtttcctgag caagcgccat agcgatccag acacgctggg
     7921 tttgtccacc agacagcgtt gcgatatccc gcatacgaaa tccagctaga cctgtagcat
     7981 ccaacgccca ctcgattgct tcatgatctt gcgtgtccat gccactgaac agtttttgat
     8041 aagggtatcg tccgtaagat actacttctt ctactgtcat acctgtaggg tgttcactag
     8101 tttgtgctaa taatgtaatt ttttttgcaa gttcttttga actgtatgta gagatatcag
     8161 agttattgac aatgatcttt cctgatttca caggtagtat acgggtaaaa cttttcaata
     8221 aagtagattt tccacttcca tttggcccaa tcaaactagt gattttccct tcaggaatcg
     8281 taacagacat gttttcaatg atttttttgt tttcgtagcc ggctgcaatg tcagctgctc
     8341 ttaatctcgt catttcaccc atcctttcgc tgaaaatcat tctcaattat gacgctgttt
     8401 caacatttcg tcaagcgcta ctttcatatc tatagccaaa tgaagcggtt gacagcgttc
     8461 gaaatatcag gaataataac caatgagaaa gattctcaat tatgttagga ggaaagaaat
     8521 gaaattaaaa acaaaagtat tcacattatc tagcatattg ctgctggctg gagtactgag
     8581 cgcttgctcc ccctcttcag ataaagaaac agctacaact gccaattcga cgacttcatc
     8641 caatagtact catacagtca cagatacact tggacataaa gtagagattc caaacgcgcc
     8701 caaacggatc atcggcagtt acttagaaga ctatctgatt gcactagggg aaaaacctat
     8761 cgcccagtgg actgttggca gtggttccat tcaagattat ctgcaagatg atttaaagga
     8821 tgtcccaacg atttcttatg accttcctta tgagaaagtg ttaagctttg agcctgattt
     8881 gctgttgatt tcttcttccg ctactgtcga aggcgggaaa tacgaacaat atagcaaaat
     8941 cgcgccaact tatgttgtaa aaaacggaac agatgtcaca tgggaagaac aactaaaaga
     9001 tgtcggcaaa gctttggcaa aagaaaaaga ggcagaaaaa atcatttccg attatcaaaa
     9061 atccatcaag aaaactcgag aagaactagc agataaaatc gagaacaaga cagctgcagt
     9121 gttgtgggtg accaacaact cagcctttat ggtcagcaaa aatcggtcaa gtggaagaat
     9181 cgtatacgac gatctggaat ttggtgttcc tgatctagtg gaagaggtct ccaaaaaagc
     9241 cacttctgac tggtctgctg tttcctctga aaagctagct gaattagatg ctgactacat
     9301 catccttgtg aacagtgaca aagatgctgc catgttcaat gaaccaagct ggaagaatct
     9361 taaagcagtg acagacaatc atgtactgca attcggacct gaatctagtt ggctatataa
     9421 cggacctatt gccagtcagg aaatggtcaa tgatatcaaa gaaaaactaa attgatttta
     9481 actaaaaaaa gaatcttcac gattagtcgt gagatgcttt ttttcttatt aacaaactag
     9541 acgcatagat tttattcttc ttttgaagca accctatttt ttactctttc ccatttttga
     9601 aaacgatggg catatagatt ttcttgatcc gttatcccct catactcctc tataagggcg
     9661 aagtctgaaa aatcaatatt cccaatatac gtatcgcctt caaacgtgct atcgatcaat
     9721 gttcgccaga tccgaccagt gtaaggaaga agttcttgaa aaatccgact accacccgaa
     9781 acatagatat cttctgagat cgtttgacta tacgacaaaa gttcatcgat cgaatgcatt
     9841 acttccgcat tttctttcgt gcgaaaattt ggttgcgttg tcaacacgat gatatggcga
     9901 taaggaagtg aaagatcccc cattccttca taggtctttc ttcccatcac taaaattcga
     9961 tccattgtat gttcgcgaaa gaaacgcata tcatttggca atcgccatgg taacaaacca
    10021 tttttgccga tcagaccatt tttatcttgt gcccacatgg aaataaacat attatccgct
    10081 ccttatgatt ttagatgttt tgagataaaa aaagtctcaa ttctttgacc agcaaggaat
    10141 tgagaacttt aaaaacatta ttttgtttca cggtgcaaag taactttgcg ttcgcgtggg
    10201 caatattttt gtttttccaa acgatcagga ttgttacgtt tgtttttgct tgttagatag
    10261 ttacgttctt tacaagaagt acactctaaa gtgatgttta cgcgcatgtt tttccctccc
    10321 atttttacaa gaatcctcta agatgactct cagacttgat tatcttacca tgattttttc
    10381 tagattgcta gtgtttttca cgattttgtt aagtaaaact acttgacgat aaatacaacg
    10441 gttttacttc tcaaacaaaa tctttttctt tttgtataaa tacccttaca cttgtttata
    10501 tagattatgt tttttaataa agggggatac taatatgcca tggaacatga aggactttcc
    10561 tgcatcaatg aaaaactta
//
LOCUS       DAFKHN010000084        10456 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFKHN010000084 DAFKHN010000000
VERSION     DAFKHN010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.084"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(283..1131)
                     /locus_tag="LY912_002310"
     CDS             complement(283..1131)
                     /locus_tag="LY912_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBM6955963.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1130..2197
                     /gene="gnd"
                     /locus_tag="LY912_002311"
     CDS             1130..2197
                     /gene="gnd"
                     /locus_tag="LY912_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBM6955964.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKRTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            2199..3200
                     /locus_tag="LY912_002312"
     CDS             2199..3200
                     /locus_tag="LY912_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBM6955965.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3197..3481
                     /locus_tag="LY912_002313"
     CDS             3197..3481
                     /locus_tag="LY912_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBM6955966.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3514..4311
                     /locus_tag="LY912_002314"
     CDS             3514..4311
                     /locus_tag="LY912_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBM6955967.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4325..5158
                     /locus_tag="LY912_002315"
     CDS             4325..5158
                     /locus_tag="LY912_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6955968.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGGPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5176..6033
                     /locus_tag="LY912_002316"
     CDS             5176..6033
                     /locus_tag="LY912_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBM6955969.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            6055..6564
                     /locus_tag="LY912_002317"
     CDS             6055..6564
                     /locus_tag="LY912_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6955970.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6601..7002
                     /locus_tag="LY912_002318"
     CDS             6601..7002
                     /locus_tag="LY912_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955971.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7114..7467
                     /locus_tag="LY912_002319"
     CDS             7114..7467
                     /locus_tag="LY912_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955972.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7501..7944
                     /locus_tag="LY912_002320"
     CDS             7501..7944
                     /locus_tag="LY912_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBM6955973.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7961..9046
                     /gene="uxuA"
                     /locus_tag="LY912_002321"
     CDS             7961..9046
                     /gene="uxuA"
                     /locus_tag="LY912_002321"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBM6955974.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            9039..9752
                     /locus_tag="LY912_002322"
     CDS             9039..9752
                     /locus_tag="LY912_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBM6955975.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         3503 a         1631 c         2282 g         3040 t
ORIGIN      
        1 aattcaccaa aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag
       61 aaaagataaa ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg
      121 aataatacca atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta
      181 ttgatgttct gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg
      241 ctttttttgt tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga
      301 aatagtatgt cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa
      361 aatcacatat agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga
      421 tcggaattct gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga
      481 agaattagct tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc
      541 aatatggatt gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc
      601 cgtcaataaa gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat
      661 aggggaacgc aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc
      721 gaaaaaatag acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg
      781 ttgtaacaac ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc
      841 catagtgagc tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc
      901 attttcttgg atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt
      961 tgtaaattga aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg
     1021 actatgactt actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg
     1081 gctgaagtcg ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc
     1141 tcattttcat aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag
     1201 agtaggaaaa aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt
     1261 gtataatgag ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg
     1321 aaaaatggga ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact
     1381 cgacatttca agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga
     1441 gatctctgaa tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc
     1501 tggagagata accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat
     1561 tattattgaa ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca
     1621 gaaaaatgaa atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca
     1681 tcaagcctgc ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt
     1741 caaagatgta gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt
     1801 cttgaaaatg atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt
     1861 ccaacttgta caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa
     1921 tcatggttcg gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca
     1981 tcccaattta agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aacggacggt
     2041 tgaaacagcg ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag
     2101 gaatctttca caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg
     2161 gtttggcgga catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa
     2221 tcgttaattc cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag
     2281 ttggagacgt tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt
     2341 tacttaaagg attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt
     2401 ttgaaaacaa agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg
     2461 atttaaaagc agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac
     2521 gaaatgctgt agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac
     2581 aagcacaagc aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga
     2641 cgctgtttaa caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg
     2701 aaattttgcg taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt
     2761 tatacatcga aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag
     2821 atatcatttg tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag
     2881 aagtcgatca gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg
     2941 atgaagaagc gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg
     3001 ttttagaaga agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga
     3061 ttacgccaca tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg
     3121 tcagagatgt cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga
     3181 gcaactatat aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc
     3241 tcaattttat ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata
     3301 cggcgcgaaa agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa
     3361 attagtattt ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg
     3421 tagttatgct gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta
     3481 gttggcgttg gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga
     3541 atcgatttcg gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct
     3601 gtcatgtata aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct
     3661 gcttttttta taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc
     3721 gggttagcag atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt
     3781 ttgcaagatg aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag
     3841 attttgaatc attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag
     3901 ttcaaacagc tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat
     3961 aaatacgcaa gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg
     4021 gaaagccatc gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca
     4081 ctagaaggtc gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg
     4141 ccggtttctc tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg
     4201 gctgaattta ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa
     4261 tcactgatac agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg
     4321 acacatggaa acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt
     4381 tatgtcccgc tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac
     4441 tggattagtc gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc
     4501 tttgcaaatg atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc
     4561 tattgcagca gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc
     4621 gattgccgtt gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt
     4681 catcaatact tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc
     4741 tatggcccga tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct
     4801 tgttttcatt gctttatatt taggggggcc attgatcgct gatgtaatca aagctttaga
     4861 gggaacagtc gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat
     4921 cgcgacaact gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta
     4981 ttttatgagt gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg
     5041 gattattatc gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac
     5101 aagcaataac aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt
     5161 taggaggaat gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc
     5221 acgaaaaaag atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac
     5281 tcttttgaac gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa
     5341 ctttataaag atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac
     5401 actcaattaa gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa
     5461 agagcagaag aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac
     5521 acgaaagcgg gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc
     5581 gtccaatata tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc
     5641 gcactttttc cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca
     5701 agacaagctt tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag
     5761 acagcgattg aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac
     5821 tatgtaaaag tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag
     5881 gaaattcttg atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac
     5941 ttgttctata cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata
     6001 ttaattgtgc tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt
     6061 gtagtcaatt tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta
     6121 tctcaaaaaa gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa
     6181 tttatgagag atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt
     6241 acaccagaga aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt
     6301 ttgatcgcaa aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa
     6361 gaattgaata ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa
     6421 tctgtttatt taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc
     6481 gtaaagaata tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta
     6541 ttgaacaagt ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa
     6601 atgaagaaga acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag
     6661 cgccgtacaa aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt
     6721 atgagaacag atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt
     6781 tatgttggag atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt
     6841 catgcattag gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac
     6901 tctatattat tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat
     6961 aacaaaaatc ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta
     7021 gcatttggga gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa
     7081 acttttattc gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat
     7141 gatccgagtg tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac
     7201 agcgtgagat cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca
     7261 gatacaccgc tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa
     7321 gttgataagt tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg
     7381 cagttcttct atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc
     7441 aatcagatta ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta
     7501 atgttggaaa tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg
     7561 gaagtaattg tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac
     7621 atccaaacat tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc
     7681 atgctagtat ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc
     7741 aatgaactga ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca
     7801 atgttgttag aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa
     7861 caaattgtca aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa
     7921 aaattagatg aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg
     7981 gtatggtgaa aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa
     8041 tgggataatt ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat
     8101 tgaggagttg aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt
     8161 agcgatccac gatgcaatca aggcagggac agatgaacga gattactata ttgataacta
     8221 tatacgaaca atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa
     8281 accaattttt ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc
     8341 tcttttatac gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat
     8401 acacagccag tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt
     8461 cgctcagctg gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac
     8521 ttatttttta gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca
     8581 tccagatgat ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga
     8641 cttgaagaaa attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg
     8701 atctttaggg gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg
     8761 catccatttt gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac
     8821 ggcacatccc tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca
     8881 agaagggttc gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc
     8941 tatgcctgga tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata
     9001 tgaggcgata agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca
     9061 tctttgatat ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa
     9121 aatcagcaca aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc
     9181 aaacagaaat ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata
     9241 tcaaatggcg agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag
     9301 tatatacgaa aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata
     9361 caatcgtggc ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc
     9421 tatatgcctt gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac
     9481 cagagatctt tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat
     9541 ttgaagactc gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca
     9601 tcaaagatca tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg
     9661 taagtttata tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac
     9721 gatttttaga aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt
     9781 atttattgtc ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag
     9841 tatctacctt atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatcg
     9901 gctctataat ttatggggct gaagaatcaa ttctgattca tcagtcccat aaattataga
     9961 gccgaaaaaa ttcattggtc gttgaatggg ctgaatagta gtgtataaaa caattttgtg
    10021 gagcgtgaag cttttatggt agaggaaaat acgaataaag tgatgttgat aaaaagattc
    10081 ctatcttgaa tatgaatcga gatgtcttga aaatgaatga gtttgaccaa tcattatcct
    10141 atcgaaattt acagtttcgt tcgattggtc tgtcaattaa tgaaaaagta aaaaagaata
    10201 tgttctagga agagggcggc acatctaaat ttttaagtaa cggacagttc aaatatcaag
    10261 cattgaaaga ggctatccta ctgtttgaag gaatacgaat atataaaaac gacaaagagg
    10321 aaaaagtagt tcattaaatc ccttcaagtg atgaaagaat gagatctaat aaaacctgat
    10381 ctttcatctg tttttttaat aacgtaataa tttttttatt ttttgtgctt tcgccgttat
    10441 tgtagagtga tttagc
//
LOCUS       DAFKHN010000085        10335 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFKHN010000085 DAFKHN010000000
VERSION     DAFKHN010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.085"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            173..949
                     /locus_tag="LY912_002323"
     CDS             173..949
                     /locus_tag="LY912_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBM6955976.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            964..1167
                     /locus_tag="LY912_002324"
     CDS             964..1167
                     /locus_tag="LY912_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955977.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            1183..1521
                     /locus_tag="LY912_002325"
     CDS             1183..1521
                     /locus_tag="LY912_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBM6955978.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            1508..1687
                     /locus_tag="LY912_002326"
     CDS             1508..1687
                     /locus_tag="LY912_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955979.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(1730..2200)
                     /locus_tag="LY912_002327"
     CDS             complement(1730..2200)
                     /locus_tag="LY912_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955980.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            2287..2985
                     /locus_tag="LY912_002328"
     CDS             2287..2985
                     /locus_tag="LY912_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBM6955981.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            3163..3504
                     /locus_tag="LY912_002329"
     CDS             3163..3504
                     /locus_tag="LY912_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955982.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            3497..4168
                     /locus_tag="LY912_002330"
     CDS             3497..4168
                     /locus_tag="LY912_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBM6955983.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            4174..4860
                     /locus_tag="LY912_002331"
     CDS             4174..4860
                     /locus_tag="LY912_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955984.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            4863..5612
                     /locus_tag="LY912_002332"
     CDS             4863..5612
                     /locus_tag="LY912_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6955985.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            5624..5893
                     /locus_tag="LY912_002333"
     CDS             5624..5893
                     /locus_tag="LY912_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955986.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            5898..6062
                     /locus_tag="LY912_002334"
     CDS             5898..6062
                     /locus_tag="LY912_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955987.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            6055..6357
                     /locus_tag="LY912_002335"
     CDS             6055..6357
                     /locus_tag="LY912_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955988.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            6354..6515
                     /locus_tag="LY912_002336"
     CDS             6354..6515
                     /locus_tag="LY912_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBM6955989.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            6512..6817
                     /locus_tag="LY912_002337"
     CDS             6512..6817
                     /locus_tag="LY912_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955990.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            6817..7173
                     /locus_tag="LY912_002338"
     CDS             6817..7173
                     /locus_tag="LY912_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBM6955991.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            7160..7378
                     /locus_tag="LY912_002339"
     CDS             7160..7378
                     /locus_tag="LY912_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955992.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            7375..7794
                     /locus_tag="LY912_002340"
     CDS             7375..7794
                     /locus_tag="LY912_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBM6955993.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            7791..8348
                     /locus_tag="LY912_002341"
     CDS             7791..8348
                     /locus_tag="LY912_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HBM6955994.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            8345..8641
                     /locus_tag="LY912_002342"
     CDS             8345..8641
                     /locus_tag="LY912_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955995.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            8718..9131
                     /locus_tag="LY912_002343"
     CDS             8718..9131
                     /locus_tag="LY912_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBM6955996.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            9440..9592
                     /locus_tag="LY912_002344"
     CDS             9440..9592
                     /locus_tag="LY912_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955997.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(9589..9864)
                     /locus_tag="LY912_002345"
     CDS             complement(9589..9864)
                     /locus_tag="LY912_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6955998.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
BASE COUNT         3811 a         1570 c         2162 g         2792 t
ORIGIN      
        1 aaaaaacact attgatatgt aaatgcagac cgccaagaaa gctttaaaat caatgttttt
       61 atgtcttatt taattatgct cttagtatag agtattactc agatactgtc aattgaattt
      121 agaaaaaagt tgttaaattt gtttacgaat ataaaagaaa ggaatgagaa atatgaacac
      181 accgcaaatt tttaatttcg aacaaaacga agttcggaca attttagtaa atgatgaacc
      241 atattttgta ggcaaagacg ttgcgagtgt tttgggttat tcaaacacta aagatgcttt
      301 gtcgcggcat gtagatttgg aagataagat ggggtcgcga atcacgacct caggtcaatc
      361 aagagagatg acaatcatca acgaatctgg tttgtacagt ttaatcttaa aatcaaaact
      421 tccctctgcc aaaaaattta aacgttgggt aacaagtgaa gtgttgccag caattagaaa
      481 acatggaggt tatctaactc cagaaaaagt agaagaagct ttgcttaatc cagatacaat
      541 cattcaatta gcaactcaac taaaagaaga aagaactgga agattaatcg cagaacaaaa
      601 gattgcagag tacgaaccta aaatctccta tttagatagc atattatctt ctacagattc
      661 agtaacaatt agtcagattg cagcagatta tgggatgtct ccacaacaga tgaataaatt
      721 acttcataaa ctaggtattc agaaaaaagt cggtaaccaa tggttattgt gcaaaaaaca
      781 catgaaccaa ggatacacaa aatctcatac aactgagatc ccgaaagccg atggtggcac
      841 taaaattgta atgaatacca aatggacaca gaaagggcgt ctatttatct acgaattact
      901 aaaaaaagaa ggatattacc ctcaaatgga tttagaggaa attggttaga aaggagtttt
      961 agtatgactg acattgcaga aatcactcaa cgagatagag aaaaaatcaa agaatatgtc
     1021 gaaagttcaa agttcttaac ttacaccatg cttgctgaaa gatttggaat tagcaaaagc
     1081 tacttatctt taattttaaa cggtaaaaag acttctgcag aagcaaacag aattatagat
     1141 tcgattatca ctatgtacga attgtaaagg gaggaacagc taatgcaata tctagaagca
     1201 aaaatcccaa ttccagaagg ctatgtaatt atctcccaag tggattatga ggagttaaaa
     1261 aaagctgatg atactggtag atggatgacg ttgccagaag tgctagaacg gattaacaga
     1321 aaatatgatt ggtttacttc tagagtttta aagaacccaa gatatagaaa tattatcgat
     1381 atcgagaaaa acaaaaatgg atttgtctat tatccagttg aaggaagaga cacatatcta
     1441 tttttaagaa gtaaaacact tgaattttta gaaacaaatt tttcggaaat cttaaggagg
     1501 caagcggatg ggaaaattta atagagcgct agtgttcagc gcaccgctaa tcatctacgc
     1561 tttaggactt tggggaagca ggcaagcgtt gataggaacg attgtttaca tggtttggat
     1621 ttttatgggg cttgatgaag ctgaagctga gtacagagcg aaaaagccaa ccgagggggc
     1681 tgactaaaaa tgaatagaaa agagaaacta gaatgtatat tactattact cagtttaatt
     1741 ctttcactaa tttctctatt gggaagtttg tatttttgat atcaacaatt ttgtggattt
     1801 gggttctatt tagagtaaat atcatttttg tttggtgatt aaggagttta ttaaaattaa
     1861 ttttccctac ttcaaatgca aggtaacaag atatagcact tttaggagga atatttagcg
     1921 gtacagcttc agagtatatt ctattatcat cgactgatcc tcctttagca attaatttct
     1981 taaatggagt agctgaccat ctgcggttta agttagcgga tgaaagttct aaattaacta
     2041 acatagctgg ttctgttgaa tagttagaaa tgattacttt tgtataaatc atatctgcag
     2101 cgaagtaaga agcattaagt tcaacttcta gttgagggcg cattcctttt atttttatcc
     2161 ctgttaaaaa cgtactcaat ataaaactta ttattgacat ccattgaaaa attgttaagt
     2221 gaaaaaaatt caaaataaac accaccagtt tttaactaaa ttataccaaa aaggagagaa
     2281 gaaataatgc aagaattagt aattttgaaa aataaagaag ctgtgactac gagcttacaa
     2341 gtggcagaaa gcttcgagaa aaaacatcaa catgttttaa gagatattga tgcactaaaa
     2401 aaagatgtgt ccaattttgg acagatgttt gtagaaggta atgaaccaga ttcatatggc
     2461 agaaatcgac gagttttctt cattagtaga gatggatttt tcttgctggc tatggggttt
     2521 acaggaaaga aagctatcta cttcaaacaa aaatacattg aagcattcaa cgaaatggaa
     2581 gatgttattc gcaagaatac tgttcctcaa acaattgaag atatgatgat ctatcaatta
     2641 gaagaaatga aagatgttaa aaaagatgtt tccatgctta aagatactat gcgaattagc
     2701 ggacaacaag agtttgaaat taagcaaaaa ggaaatatga aagttatggg agttctaggg
     2761 ggaaaagaaa gccgagctta tgaagaaatc agcaaaaaag tattctcaaa attttggtct
     2821 gaatttaaac gtaccttttc aatcccaaga tatggcgagt tacctcgtaa gagattcgat
     2881 gatgctgttt catttattga aatgtggttg ccagaaactg cgatccgtat ggaaattgat
     2941 caactgaaca gacaacagag actttttggt gatgacaatg aatagagctg aagcgctaag
     3001 aatagggacg gcaattgcta attgctggtg gaaatactat aaaccaatca tcctaagcca
     3061 acaacatatt gacaagcaaa aagcatggca acaaataaaa aagtgactcc gccggcaagc
     3121 aaagagtcac aaagaaaaca catcataagg agattttagc atatggaaaa agaactttcc
     3181 actctagatc aatatttgat tgatcctgat tggggcaagc cgaaaattga ggaaacaagt
     3241 ggtcgaaaaa tcagacgaaa tcttttgacg aatgaagaac tagcttggga tcaagatgat
     3301 ttaggcaacc atgtaactat ttgggatcat gtttatctta tccatctatc gaagcattcg
     3361 aataaacctg aatatattta cgtcatcgaa gatggcttga ttgatgcgct agaagagtac
     3421 gacagagata acttgattga tatctcttat tacggaccag gtaagaaata cattgctgaa
     3481 atggaggcag aatttgatga gtgaaatcaa agggacaacg aactttgaaa aactttttag
     3541 tcgtaagtta aataaaattc tcaagaaaaa aggaaatttt gattatttat cttgggctca
     3601 cgcgtgggag attatgaaaa agaatgatcc acaggcaacg gtaactatta atgagtacaa
     3661 acactacagg gttgtttctg gaactcatca agactttctt gttgaggaat ataaaccttt
     3721 tcttatggat gaaactggga cttatgtatc tgtctcagta acggttaaag gacacacgga
     3781 aaccgaatta tttcctgttt tagattatcg aaaccaacca gttgttaaac caaatgcaat
     3841 gcaaatcaat aactcattga agcgatgctt tgtgaaagca ttggctctac acggactggg
     3901 attatatgta tttcaagggg aagatattcc aacaccacct agaatcgata caaagaaatt
     3961 aaacatgcta gagacgattc tagaagcttt caatgagcag atgggtaaag atatgaccaa
     4021 aaccttaatc gaatatgtta atgagcagac agataaatta gggctcttag ctgataacgt
     4081 tgaaactatt gaacagttaa gctatgagca atgtgccttg atggagcgag caatagcagc
     4141 taagagaaaa gaattagata agaagtgata tgagtgttta aaccattaat cgattcatat
     4201 tcagcggttc tgaaaaagtt caaaggaaaa gacataagcg caaccatcaa tgaggaagtg
     4261 aacattgatc gactaaagac gatgtatgac ggctacgatg gtgatcgagt cattgaaatt
     4321 cgttttattg atcctagacg tttcaccgta cagcaacgaa acttcatcta tgcgctgata
     4381 ggcgatattt ttatcgatac aggcatgcca acggacttct ggaaggaatt cttctacttt
     4441 cgttttgaag gtgtcacagg gcgcaaaata agcctgaaag acgaatcgaa tacaactgtg
     4501 agtgatgcca atgtcttagc aaatatcatc ttagatttca tctttgaaca tcatattcct
     4561 ttcaaagaag gctatgagat tttacctgcg aatcaagaat attacttcta caaatgcatc
     4621 acaaaaagag tctgctgcat ctgtggcaaa acaggagctg acatcgatca ctttgacaaa
     4681 gcgctaggaa gacgaaagcg caaagaagtt gatcatgcag agtacacatt tgcagcactc
     4741 tgcagaatcc atcacacaga gaagcacaaa ataggtgtga ttaatttcaa aaataaatat
     4801 caaatcaaag ggatcaaatt aaaccagaaa acaatcaaaa agttaaatat tggagggtaa
     4861 aaatgacaga acatcgaagt tattatgcga ttataccagc caacgtaagg tacgacaaaa
     4921 gacttaaacc aaatactaag ttgttatacg gagagataac ggccttgtgt aatgaaagag
     4981 gcttttgttg ggcaggcaat gagtactttg cagatttata tggtgtgaat aaagagacca
     5041 tatcgcgatg ggtaagtgat ttgattaagt ttggatactt gaatcgggaa atcatttaca
     5101 aagagggtac caatcaaata atcaataggt acctacgaat taatcaatac cctattgacg
     5161 aaaaacgcaa tacccctatt gacgaaaaag tcaaagataa taatacatct attaataata
     5221 catttaataa tacaaaagaa tatataagag agttaccgcc ttcgaaaaaa tcgaaggcta
     5281 agcccgtccg tcataaatac ggagagtata aaaatgttct tttgtcagat gagcagatgg
     5341 agaaactcaa aacagaattc cctaatgatt accaagagcg aatcgaacga ctgtcagagt
     5401 attgtgaatc atctggtaag acttataaaa actatttggc aactattcga agttgggcaa
     5461 ggaaagaaaa aagtgaacct aagaacgcaa gcagtggata caagcgcaca ggaagacgag
     5521 agaagcttcc tgaatgggca atcgaccaag aagcctatct caagaaaaaa gcgctagaac
     5581 gagctaatag acaatcaaaa gcaccattct aagaggtgga aaaatgaaga tcgattatct
     5641 agaactaatt aatgaaatag cgaattataa aaagggcgag gaattagacg tcctgagaga
     5701 cgtatatgat caactcgaag aagctggaat tgaaggaatt aagaatgatc gttcgagttg
     5761 gagtaagctc agatactatt tcgcacttta tatcgataca acacaattaa gaaatttagc
     5821 atataccaaa ttactatttg ttgattgtgt taaaggcttg caaaaacatc ttaatgaact
     5881 tgagcaggtg taatcagatg gacctaaaga catttacagc acagattgaa ctaatgcatc
     5941 aagaagcttt aagacaaagt gtatcgtacg aagacaagtg gctcaacacg ttccatggcg
     6001 gacgtgagag cgcacttgat caagtactca aattactgaa aggagaatgt cgggatggat
     6061 aagaaagcgg caatgcagcg aattatcgaa ttgacttatt cagaagattg gcaaaatgac
     6121 aaagaagctg cttcagaagt gatgaggctt ggaagagcga tgtgggcaga caagagcaac
     6181 aagccaagac cacgaaaaat cgcaatttgg cacggtgaca aacttctagt gatagggaca
     6241 gctgaacagt tagcaagtct cacaggcttg cacgagaaaa tcgtgaggaa aagagcaagg
     6301 tgtggctaca cagacgctaa gaagagaacg tttagatacg tggaggaatc atcatgacaa
     6361 cagaagaagt gattcaaatg cgtattcgaa gccttcagcg tgagattgac gatctggaac
     6421 gaacaaaggc agtgatggtc aatgaaacgg cgagaaaggc aatcgatttg cacatagaga
     6481 atttaagaag ggaaatccat cgattggagg aatgagcgtg gataagaaag cagcaatgaa
     6541 aagaattgct gaattaacca agtcagaatc ttggcaagaa gacaaagaaa tagttgcaga
     6601 agtccaaaag ctcggtaaat caatgtggac tgaaaagccc aaacggagaa cgccgagaaa
     6661 aattgcaatc tggcatgatg accgaatttt agtaacaggt actgctgaac agttatctga
     6721 aattactgga ttaagcaaaa acattatctg ggatagagct aggagcttat ggattgattc
     6781 aaaaggacga cagtttaggt atgtggagga gagataatgg atctcattac acaatacagt
     6841 gacatcatcc tcaagaaaat catgatgaag attcagaaag ataaaaaatc aaaagaacga
     6901 gctgaattag ttaagttaga aatggctgaa acaggagcag gagtgcgaag tagcaggcat
     6961 tggaaagcag cagcaaacat tgaattttat tacaacgaaa ttcaaaaagg gttcgatcag
     7021 atgcgtgagc tggatcggca aacaaattgg agcaagaaac ttcatcaaga tcgtttcaaa
     7081 tttgtagaga agtataaaga aatattagaa gagtatttga ggaggacagc aaatgataaa
     7141 aaaactcgtt caattcagca tggatttata tgatatcgaa tcaggagcaa cactatctgt
     7201 ggaatcggac catctaatca taaattttgg tggaaagcgc cagattattt tgtgggtagt
     7261 tgatgatgta ctgtttccag aaattgttca tgatttcgaa gaatcaaaag cggttgagtt
     7321 tgaaatagtg aaaaaagtaa tggaattgat tgaaaaatac gaggaggaca gcgaatgata
     7381 ccgaagttta gagcgtggga taaacgaaag aacgtaatga gagatgtagc cgtcttgcat
     7441 tttactaaaa acggcaaaac aaactttatt gaatattgga taaatcctac cgaattgaaa
     7501 tcatatcacg tgcgaaacat cgacctcatg caatccacag gaatgaaaga taagaatggt
     7561 gtggatatat ttgaagggga tatagtatta gtcagcgtgc gaaatggctt cgattactta
     7621 gataataaag tctgtattgt caaaaattca atagattatt ccggattagt ttgtgccact
     7681 gttgatgaag acttagagta tcaaattttt aacacagagc tgtttgaaga atacacgtac
     7741 gaagtcaccg gaaatatata cgagaatagc gagttattgg aggaacagcg atgaataaac
     7801 aggaagcaat caaaaagtta gaaagtatta aagcgatagg aaatgatgca atagctgctt
     7861 gctataacga gagtataaat tcaggtatta cgttaatgaa aaaaatagac gaaccgcaga
     7921 aaccagttat tccacaactc gtggccggtt ggcttgagaa atctacggac ccttttacaa
     7981 aagctgaaaa aatagcgtat ttaatcaaat ctaaagatgg tgattcatat tatttctgtg
     8041 attggtttgt acgagatggc atagtgacgc aagagcaagg agaagaatta ctcgcttggg
     8101 caacaagaca atcatatgaa acactattga gcctatacaa cggctacgag gttgagaaag
     8161 agccgttatg ggcaataaag aatgccgatg gaaactatct tactaaatgt gctttatggg
     8221 gaaaagatgg agtaaattat agttttgaat gcaatccatc tcatcgattg cttttcactg
     8281 ataaagcaac agcggatgct gcagcattgt tggtgaatgg aacagtggaa gaggtggtag
     8341 aaagatgaaa ctaaaagacg gattttacgc tagcagtcac ggtatcggcg gtttaatgct
     8401 agatatgccg acaaagaacc ctaaaacacg caagaaatca aaattcaaag tcggtgacat
     8461 ggtccgctgt gaagcagaag agttcgttta tccgttcaga ggatacgtta aaaagatact
     8521 gtcaaactca gcaatcattc gtattgaaaa tacaatgaag tgtgatcgtt cgactgcaaa
     8581 acacaagcat tatttagctg tagcgagatt agttgacatg gaagtaatca agagcaaata
     8641 aaaaaagccg gatcgctccg actgattcaa taaatccaac acatttatta tatcacataa
     8701 aggagcggtt tgacttgatg caattgttac gagaggtaga tttcaaacag acaagatgta
     8761 atgcgagaga tgtgctgaag aactttcggc gtttggagcg gatggcaggt cgctctttga
     8821 tagatattaa gtcgccgatt ataacggata tgccgaaggc accgaagcat ggcaataagg
     8881 cagaagacgc gattattcag atgatggata tagaaacgga gagagatgcg attctagcgg
     8941 ctttgatggc tcttagtctg attagtcgtc agatactcta ctacagcttc tgtgtgccag
     9001 atagcttctc aaactacaga attagccgtg aagtgggtta ttcagaaaga agtatacaac
     9061 ggatgaagtc ggaagctcta atagagtttg cagaagcata taaacacgga aaaataattg
     9121 cttataaata atttggcggt tttttggcgg aatgatggcg gtttttagac atttaccagt
     9181 gttattatgg tagtgtcgaa agattaggaa acaggatcga caaaataaac gaagggaggc
     9241 aatctccctc atcgttttaa acttcttctt agatagacag caactaatta tgaagaaaag
     9301 gatgtgaatt caactcctcc taaattcttc atcggttgct gtttattttg attagacagc
     9361 agcactcaca aaactaaaca tgttcttgtc gtctttcaac tgctgctgtc tattaattta
     9421 tgtattggag ggaagaaaaa tgaaattatc agtagaaggc actccagaag aaatacaaga
     9481 attgctccaa gctattggta gtagcaagga gcaaaaggta agtgtttcta attcagatat
     9541 tgacggtatt tgcaattgtt taaacagaga aaaaatatct aatccttact aagagaaaat
     9601 atgttcgtta atgaatttcc aattttcctc tgtagctcta ccttgataat ttttttgcag
     9661 ttcacagatg aataaggaat cgttattatc aagtactgta tttaattttt cacacatttg
     9721 atttggattc aaattagttt taactaacca aaaagatttt tgtagcttta tatatgcccc
     9781 aaattctttt attatttcaa atactttatc atacttttgc cctgggttat taagatcata
     9841 actaatcatg tagggtttat acatgttgtc ttgcacatcc ttgttttata tttcagcgga
     9901 ccactcgctg ataaataaaa ttatacgctt agtatttatt ttcacaatat taatttatcg
     9961 taataacttt tgagtaaata gaacaaaaaa cctgcactag tttccgctag tacaggcagt
    10021 gactatatcg gttgataatc tagcatatat taaaaataat tgcaagaaaa gaaatttata
    10081 gtggtttata ccaaattatc aaagcaatgt tattttgttg ctgtctattg ttttttaatt
    10141 attcacacga taactaaagg tgggtgaaga gaaatgattc cattaataat ttcaattttt
    10201 gcgctctgtc ttaatgtcta tatgattgga tttaaaaatg ggcaaaataa aaaatagtag
    10261 cagccaagaa taattttata gtgtcactgt ggcggaaagg gtagacgcta agcatgtgtg
    10321 ctaggtcaat gcttc
//
LOCUS       DAFKHN010000086        10210 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFKHN010000086 DAFKHN010000000
VERSION     DAFKHN010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.086"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1023
                     /locus_tag="LY912_002346"
     CDS             <1..1023
                     /locus_tag="LY912_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBM6955999.1"
                     /translation="ELKPKHERQNFLVGDDRLDHAVAFLWKDPQTGETVGASYQGTIV
                     DFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKFFESSIDLLSYAALNREKLQDAW
                     LVSMDGLKHHVISHYVEESISELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDP
                     FTNKKIRCERGIPNDWQVPKEYKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVS
                     AHDVQSTFGKMLAKGEPVETIDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKD
                     VNAGILLSYKAEQYYKGYKKHEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
     gene            1034..3043
                     /gene="topB"
                     /locus_tag="LY912_002347"
     CDS             1034..3043
                     /gene="topB"
                     /locus_tag="LY912_002347"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBM6956000.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELYSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            3159..3308
                     /locus_tag="LY912_002348"
     CDS             3159..3308
                     /locus_tag="LY912_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956001.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3389..3985
                     /locus_tag="LY912_002349"
     CDS             3389..3985
                     /locus_tag="LY912_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBM6956002.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3998..4897
                     /locus_tag="LY912_002350"
     CDS             3998..4897
                     /locus_tag="LY912_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBM6956003.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            4900..5031
                     /gene="ssb"
                     /locus_tag="LY912_002351"
     CDS             4900..5031
                     /gene="ssb"
                     /locus_tag="LY912_002351"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBM6956004.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            5053..5385
                     /gene="ssb"
                     /locus_tag="LY912_002352"
     CDS             5053..5385
                     /gene="ssb"
                     /locus_tag="LY912_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBM6956005.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            5407..5664
                     /locus_tag="LY912_002353"
     CDS             5407..5664
                     /locus_tag="LY912_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956006.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(5823..5945)
                     /locus_tag="LY912_002354"
     CDS             complement(5823..5945)
                     /locus_tag="LY912_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBM6956007.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            6135..6359
                     /locus_tag="LY912_002355"
     CDS             6135..6359
                     /locus_tag="LY912_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956008.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRNQLVIESMQIRNPDHFTRLMGI"
     gene            6807..7013
                     /locus_tag="LY912_002356"
     CDS             6807..7013
                     /locus_tag="LY912_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBM6956009.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7013..7264
                     /locus_tag="LY912_002357"
     CDS             7013..7264
                     /locus_tag="LY912_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956010.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            7280..7717
                     /locus_tag="LY912_002358"
     CDS             7280..7717
                     /locus_tag="LY912_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956011.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            7710..8405
                     /locus_tag="LY912_002359"
     CDS             7710..8405
                     /locus_tag="LY912_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956012.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            8786..8965
                     /locus_tag="LY912_002360"
                     /pseudo
     CDS             8786..8965
                     /locus_tag="LY912_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9027..9211
                     /locus_tag="LY912_002361"
                     /pseudo
     CDS             9027..9211
                     /locus_tag="LY912_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358324.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            9245..9676
                     /locus_tag="LY912_002362"
     CDS             9245..9676
                     /locus_tag="LY912_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBM6956013.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
     gene            complement(9850..>10210)
                     /locus_tag="LY912_002363"
     CDS             complement(9850..>10210)
                     /locus_tag="LY912_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBM6956014.1"
                     /translation="VDIENSINEWLQSVPKNLFKSITFDCGKEFSSWKSISNTNDIDI
                     YFSDPGTPSQRGLNEHSNGLLRKDGLPKEMDFNQVNQGFISSVASKRNHIPRKSLNYQ
                     TPLEVFLSYVNGKFCLA"
BASE COUNT         3641 a         1737 c         2128 g         2704 t
ORIGIN      
        1 gaactaaagc cgaaacatga acggcaaaat tttttagttg gagacgaccg tttagatcat
       61 gcggttgctt ttttatggaa agatccacag acaggagaga cagtaggggc aagttatcaa
      121 ggaacgatcg tcgattttaa tcgtttcggt aaacggggaa cgtataaaca cattgacaag
      181 aatcctacgc caaatcacgg atttaattta aaaataggcg atccgaagca tttaaaattc
      241 tttgaaagta gtattgatct gttaagttac gctgcattga atcgggagaa actacaagat
      301 gcctggttag tttcgatgga cgggttaaaa catcatgtaa tcagtcatta cgttgaagag
      361 tcgatttctg aattaagacg aaaacaaaca tttcctcaat cgattgaaat atgtgtggac
      421 aatgatcgtg caggacatat tttttatgaa aaagaacaga tgaagggaat cgttgatcct
      481 tttaccaata agaaaatccg ttgtgagcga ggaattccaa atgattggca agtacctaaa
      541 gaatacaaag ctacttatga agcagtcgca aaagaaatga gtgttgaacc tgaagcaatt
      601 atggccatac acaaaactga aactaattta cagctgacaa atcaattggt gtctgctcat
      661 gatgttcaat ctacgtttgg aaagatgttg gcgaagggcg aaccagtaga aacaattgat
      721 ttgaaagaag catgtaccac ggtcgcgaag gaactgaaag tatgtgaacg cgcagatgga
      781 acatacaact ttgatcgttt ttatagtaga aaagccaaca taaaagacgt taatgcagga
      841 atccttcttt cctataaagc agaacaatac tacaaaggct ataaaaagca tgaacatgaa
      901 tttgtacctg aagtgaaaaa ggattggaat gatcaattga agcatgagat ccagcaacaa
      961 gaaatcagaa agcaaaaacg tgcgatgttg tttcaacaag gcagacaaca agaaagggag
     1021 tgaagtcgtc actatgaaaa ccgtcatttt agcagaaaaa ccgtcacaag cgaaggctta
     1081 tgccgatagc ttttctaaag ctacccgaaa agatgggtat tttgagatcc aagatcgatt
     1141 gtttacagga gaaactgtga tcacgtatgg ttttggtcat ttagtcgagt tatattcgcc
     1201 cgatatgtac gatgaaaaat ggaaacaatg ggcattagaa catttgccta ttttccccaa
     1261 tcaataccac tatcatgttc ctaaagataa gaaaaagcag tttagtgtcg tcaaacgaca
     1321 gctgcagtca gctgatacga ttgtgatcgc gactgatagc gatcgtgaag gggagctgat
     1381 tgcctggtca atcattcaac aagcaggcgc caatcaagga aaaaccttta aaagactttg
     1441 gatcaactcc ttagaaaaag aagccattta tcagggattc caacagttac gagacgcaga
     1501 agagacctat ccaaaatttg aagaagtaca agcacgtcag atcgccgatt ggttaattgg
     1561 gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac caggaagttt
     1621 ttctttaggt agagtccaaa ccccaacact ctatatgatt tatcaattgc aggaaaagat
     1681 tagaaacttc caaaaagaac catattttga aggaaaagcc caagtaatcg ctcaaaatgg
     1741 cgcatttgat gcgaagcttg atccaaatga aacccaagcg acacaagaag catttgaagc
     1801 ctatttaaaa gaaaaaggtg ttcaattagg aaaacagcca ggtacgatcc ttcaagtcga
     1861 aacagagaaa aaaagtgcgg ctagcccacg tcttttttct ttatcgagcc ttcagtctaa
     1921 aatgaatcaa ctcatgaaag ctagtgccaa agatactttg gaagccatgc aagggttgta
     1981 tgaaggaaaa tatctaagct atccgcgaac ggatacccct tatattacgg aaggggaata
     2041 tgcgtatctg ttggatcact tagacgaata caagcatttt ttaaaagccg aagcgattcc
     2101 gactcctatt catacaccga atagtcggta tgtgaataat aagaaagtcc aggaacatta
     2161 cgcgatcatt cctacaaaaa cggttatgac agcagcggct tttgaacaac taagtccact
     2221 gcagcaggct atttatgaac aagtgttaaa aacaacggtg gccatgtttg cggaaaagta
     2281 tacctatgaa gaaacaacga tcttgacgca agttcagcag cttcagttaa aggcaatcga
     2341 aaaggtgccg ctagatctag gttggaagaa gttatttgga aaagagagcg acggaaaaga
     2401 gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga cggtggatct
     2461 acaagttctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta cgttgatcac
     2521 tgcaatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca tattgaaaga
     2581 agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct tgaaacaaaa
     2641 ggaatatatc aaggtagaga aaaataagct cgtggtgacg aataaaggga ttttgctttg
     2701 ccaagccgtg gaaaaagagc cgctgcttac gagcgccgaa atgaccgcca aatgggaaag
     2761 ctacttgtta aagatcggtg aacgaaaagg aacacaaacc acttttctag ccaatatcca
     2821 aaaatttgtc tctcacttat tggaagtcgt accagggcaa atccaatcca ctgattttgg
     2881 atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc gtcatttagg
     2941 aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg cagcttgtac
     3001 gtctgaagcc tgtgatttta aaaggtcaga agggttcatt tgaagcaacg attgttttaa
     3061 aagaagactt cactacaggc tttgaatttt ctgaaaagaa aaaaacgaac ttcaagaaaa
     3121 gaacacgccg cactgcaaaa taatggaggg ttaatcttat gcgtaatacc acacacaaac
     3181 aacaagaaat cgaaaatcaa aaagccaaaa ttcgttcaga acaggaaaaa atgcgtgcca
     3241 gcaaacgaag actgcagcaa ttgaagaacc agcagaggat tcaaaaagaa atcgaattag
     3301 atcgataaaa tcttcctaac tattgtatac gtataaactt atgttatact gtttttataa
     3361 gtttatacgt atacaaagga gggagaaaat gacaaaagca atggtataca agctgctaga
     3421 agaatttaat ggaactttgg ctttgaagga tgccaaaaaa gcgggcattt ctcctgtaac
     3481 gatcaaacgt atggtagatc gaggggagct ggatcgagag tatccaggtt ttttcacctt
     3541 acctggtcaa tttcctgatg aattgtttat ggcgcaaaaa aaatatgaac gcggcattat
     3601 ttcacatatt accgcgttag atttgtatga tttaacagat atgatcccta gacagatcga
     3661 tctgactgta ccttacggtt atcacgtttc tgaaaaagga ttgaaggaat tcgcagttga
     3721 gctacactat acaaaagcgg aatggtatga attaggtaag attgaaataa aaagtcgcta
     3781 tgggaatcct attatagctt atgatccaga aagaacttta tgtgacattt ggaatccctg
     3841 gtataccgtt gaggatgaaa tcaaagtaaa agcaatcaaa aactatatgg agtcggacag
     3901 aaaaaatctt agaaaattga atgagtatcg acgaatttta ccaacagaca aaacgatgcg
     3961 ttcttatatt atggctttaa attaaaggag aagatacatg acacctacgc agttaaaagc
     4021 aaaagtgaag aatatttcta gagaaaaaga agttgatccg cagcttgttt taagacattt
     4081 tatgatggaa aaattcttgg aaaaaatctc agagtctcct tatcgtgaaa attttgtgtt
     4141 aaaaggcggc ttcttgattg gctcaaagta tggcattgaa aatcgcacaa ccaaagatat
     4201 tgatacgact ttacgggaaa tgaaagtaac caaagaaaca ttaacaacgg ttctaaacga
     4261 aattttttca acgccgacga aagaaggcat tcaatttgag attcaaggaa tgaaagaaac
     4321 gagagaagcc gattactatc caggatttag cttacgtgtg ctggcacatt tggaaaacat
     4381 gcggccagat tttaaggtag atgtgactac aggtgactcg atctatcctg caacgatcac
     4441 tcacagtcat aaattgatgt ttgaggatcg aacgattcct ttggaatcct atcctacaga
     4501 acaaattatt gctgaaaaat taagtgcaac ctttgatttt ttaacagata attcgagagg
     4561 aaaagatttt tatgatctct atactattcc taaaatggag aagatcgatg agaagacctt
     4621 gaaagatagt gtgagaaata catttacacg tcgaggaaaa actgatccgt taaagatata
     4681 ctatgaaaag gatatggatg tactgaaaaa tagtcacgag ctaaaagata cctggaagaa
     4741 atatcaaaaa agcaatcctt atgctgcgtc gatcacgtac gatgagacaa tggattcgat
     4801 tagtaatttg atggaaaaag tgattcacgt cgaagaaaaa gagcgaaaac tagcttatca
     4861 aagacaccaa cagatgaata gagaaatgga gagataaaga tgattaataa tgtgacatta
     4921 gtaggacgct taaccaaaga tcctgattta cgttataccg caagtggtac tgcagtagcg
     4981 acttttaccc tagccgtcaa ccgaaatttc acgaatcaaa acggcaattg agaagccgat
     5041 tttattaact gcgtgatttg gcgcaaacca gcagaaacaa tggcgacatt agctaaaaaa
     5101 ggtagcttga ttggtgtagt tgggcggatt caaacgcgga cttacgacaa ccagcaagga
     5161 caacgtgtat atgtgactga agttgtagca gataactttc aactattaga aagtaaagca
     5221 gcgacagaga gccgtgcgca cgctgatcaa tcgtccacca gtccaagcac cgccaccttt
     5281 gaacaacgga atacagcgac gcctaacaac aatggattga acgcttcaca gaatccattt
     5341 ggtggacaat caatcgatat tagcgatgat gatctaccgt tttagtttga gaaagaagga
     5401 gtaagcatgg caaaaaaaat tagtctgacg atggatctat tgatacccgt aattgcattt
     5461 atagacggga tttctttggg cgtcactgaa aatcctttgg taaatagaat tgcgaaagga
     5521 tcactatttc ttgtattcgt gtatcttgtc tgttcttatc ttttaaaaag agcaggaaag
     5581 gataattcct tttggcgatt gactaaagtc acagtagcag cgacagctgt tatacttacg
     5641 gctattctac cgctttatat gtagagttaa cgggaaatcg ttgaacttct tgcgaaatat
     5701 tgctataatg aacatgaaaa agaggagttg cgctaacaac ccctcattaa cagcaccgat
     5761 taaagaacgg tggcagaata ttagttattt ggaaataacc gctgacctgc taaagtagac
     5821 ggttatttct ttttgtcatt tttaagcata tttacaatca aactaatcaa agcaatggta
     5881 aacataccaa aaccaagaat ggtttgaatt gtctcatatg cggacaaaag gcttactcct
     5941 ttcatagatt ttagcactta cattcataag caccaccacc tttccagaag tcgccaccgt
     6001 cttcaaactt tactgtcttg actattatag catatctaaa atcgaataaa aattctcaat
     6061 tttagctgtt tttgctataa ttttagcgag gtgatcgtga tggaacaata tattggttta
     6121 ctcgataaat tagggtgatc aagacacagc cattgcttgt gcgatttaca ttacgcacga
     6181 gtcatgaacc aatcaattgt gtagtggcca atatagaaat agcggataaa ttgctgattt
     6241 tggaagaagg caagtatact atttcagtga caggtcactt caataaacga aatcaactag
     6301 tcattgaatc aatgcaaatt agaaaccctg atcattttac gagattaatg ggcatataaa
     6361 taaaagaaga gctgcagtcc taaatgagga ttgcagctct ttttgtttta catagaaaca
     6421 agaaaaatga aaaggccttt ttaggaaggc gcaagcgcct tctcaattga aaaacctctc
     6481 tctcactcca accgccaccg ccgttcgaga agaaaggaag tgaacgttgc acgttcacta
     6541 agataagggg tcttgcaaag caagacaaaa tagaaaaaac ttcctctcac caaaaggttc
     6601 gttcctgttc gctatctctt tattgatttg ccagaccggc aacaagttgc cttttatcac
     6661 caaaaagcga caaggacaag ggtaaatggc acgctgcacg cccttgtcct tgtcgctttt
     6721 agttgattca ttctggccaa caaatcaata aagaaagaac taacgaaagg aagtaaaacc
     6781 tttcctaaga ggaggcagaa tcaatcatgc gaaagaaatt tgattattgg ggtgttccct
     6841 tcagcgaatt attcccaaac tatcatgcac catatactgt cgaatgcgat tgtggagaaa
     6901 gagcgaaatg tatcaaaagc tattgtttgt atcaatgtcc aacatgcggg aaaaaatata
     6961 ccttgtctta tggcgattat attttgattg atgagaaagg aaagaaacgc tgatgaaaac
     7021 acaacacaaa ttattgactg taaaagaagt cgttcaaatt ttggtggaca aagaagtcat
     7081 ttctgaaaaa gtagcagaag ctttacttat tccgcggtac tggacgatag aaaccccttt
     7141 agtagaggat gcaccgacta tgctatttga agacctagtg aagattgcag gatatgaact
     7201 gcattatcaa gaaaacatgg aaacttatga aaacgaatat tggttaacca aattagagaa
     7261 ctaaaaagga gaaaaaaata tggctcaaaa ttactatgac gaatttgtca aattaccttt
     7321 ggataaaatg gcacaaaaaa tggaggatat gacattccta tacaatgaga cacgtgttcc
     7381 aaaaaaacat tataaggaaa gattgtcggt agctgtggaa gaaatgattg aatcgggtgt
     7441 cgaaatgaat ctcattgcga cctactatcg aacgcttgaa gaactgaaaa agcaaaatgg
     7501 acaatggttt ttccaagcct tactatgctt ggaagcaggc gtcaagccaa acactatcaa
     7561 accttctgaa taccaagctt tagaactaac gtatgggaaa tttgtcgaaa cgaaaaaagc
     7621 caagactgtt tcaagtgaat ggttggacta cttagaaaat gtcaacaagt atggcgcatg
     7681 ttacatcatg aaaaaggagg acaacgaaaa tgaataaggt gatttatcaa ctaacaacgg
     7741 aagatgtgtc acacttttta acaaacaaag aacatttgaa tgaagtaatc agacggattc
     7801 aaaaagactt tagttgtatg gaagaaatga agtactttat tcaaagagtc gaagaacaat
     7861 tgtatttgga aagtgaaacg agtcaaacga aggttacagt cagcaataat tatttagacg
     7921 tgtataaacg tcgtcctgac acattaaaaa aaggagcgga gcttctacga ctagaaacag
     7981 aaaaatatat catgaatgtt tacctagaaa ggagtgaact ggtcgaaaac tttgtcagct
     8041 acacgatttg caggaaacac tattactcag aatcagaata ttattcaatt tttgagagca
     8101 tggaattaat ggaagagcta aacagcaaag atgcgacggt agacgattat taccttgtat
     8161 ttactaaatt tttgacgtgt gggacggaat ctatcgtgtt aatgggaatg gattatgaac
     8221 tcgctgtacc cgaagtattt ttgagggaat atgtagaaga agtagataac ccaggcgacg
     8281 actggtacac gactttaact gattttttag atacctacac ttacgacgat acagaagaaa
     8341 tccaaaatga acttgaccgt aaacgaatgc catatcaacg atttgaaagg aaaaaaggtc
     8401 aataaccatt tataccgaaa agtgagaatg tgtgaaataa aaacaaaaaa ccttgaaatt
     8461 aagggaatgg ttcttatttc gcaccaatcg ctccaaccgc ccccgccgct taggtggtgc
     8521 gaaataagcg agcaaagccc gaaaacctaa gagaaagaag gagatttata tgaacaaaat
     8581 tattccctta ttattagtcc tatttgttgg agaaatactt atgcgactta gtgcagctgt
     8641 acatttaaac ctcgcagtat ttttggtaat actaatgttt tgtttgatct tttggcgatt
     8701 tgtattagcc ctcgtaagtc tactattcaa gatgattgca gccatatttt tcataggatt
     8761 atttcgatga aaggagagag taccaatgcc aattgcaata ggaaataaac ggttacccgt
     8821 gacgttggat gaaaagagac aaaaagaatt gcagtaacca aagcagaagt acggcaaaag
     8881 tgaatccagg attatgtgta ttgcgttaga tttattgatt gcgcaagaaa aagcaggatt
     8941 tgacatacca gcactcaaaa agtgatcgca ctttgcgcac gtgttaatac gtgttataat
     9001 tattttgtaa ggaggtatag tgcacaatgc cacttacggg aaaagaaatg cttaagttat
     9061 tgaaaaaaat ggctgggttg agcgaaggca agagggattt catcatcatc tttataagga
     9121 tggtgttaga atcactgttc ctgttcatgc caatcaagat cttggccgag gacttgagcg
     9181 aaaaatttta aaggatgcgg gattgaaata atctcgcatt cgattaaaga aaggattgac
     9241 tgaaatgtta agtgagcctt tagcaaaaac ctatcctgct atttttagcc cagaagaagg
     9301 tggtgggtac tttattgaat ttcctgatgt tcaaggtgct tacacaggaa ttaacgaaga
     9361 cgatatatct tatggaattg ctatggcaca agaggtgtta ggtatggttt tagcagatta
     9421 tattgagcat gaagatctac ttccagaacc aacaccaatc aataagattt ctgttgaaga
     9481 tgattctttt actactttaa ttcgtgtaga tgttgccaaa tatttgaaag acacagaact
     9541 tgtcaaaaaa accttaacaa ttcctcaatg ggcggataag ctaggcaaaa gggctggcat
     9601 aaatttttca gtccttctaa cagaatcaat tgcagataaa gcagataaca ttcttcgttc
     9661 tggaagaaat aattagaact caaaagggtc agaaacttaa aaatctttgg cttctttttt
     9721 tactacaaag atggcttctt taaattattt gcctgattga tttaaaaaaa ttgcgcaaag
     9781 actacgagct aattaagttg ctcgtggtct ttttttatga aaacttttta gatcttatta
     9841 tttgtcaaat taagcgagac aaaactttcc atttacgtaa ctcaaaaaaa cttctaatgg
     9901 tgtttggtaa tttagtgatt ttctagggat atggtttctt ttggacgcaa cggatgagat
     9961 gaatccttga ttgacttggt tgaagtccat ttcttttggt agtccatctt ttcggaggag
    10021 tccgtttgaa tgttcattta atccccgttg ggaaggcgtt cctgggtctg agaaataaat
    10081 atcaatatca ttcgtattac taatactttt ccaactagag aattcttttc cacaatcaaa
    10141 ggtaattgat ttgaaaagat ttttgggtac ggattgaagc cattcattaa tcgaattttc
    10201 aatatcaact
//
LOCUS       DAFKHN010000087        10058 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFKHN010000087 DAFKHN010000000
VERSION     DAFKHN010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.087"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..621)
                     /locus_tag="LY912_002364"
     CDS             complement(<1..621)
                     /locus_tag="LY912_002364"
                     /inference="COORDINATES: protein motif:HMM:NF026247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpsG family protein"
                     /protein_id="HBM6956015.1"
                     /translation="MDTEASLEINQEKSVSQKKWSTSNKILSGVLLLIMWIIMAFNTQ
                     NADYYAYSVLYNGIAQFGMDFSSDSIEPGFRAVMYVCTFISSQYQIFLLIISTVLLSA
                     LLYVIRLFTTNVFLVLFLFFIFGFTSQAIQVRMFSALIFILLAFYHLTKLRGSKAIFK
                     YIFFILVAGLFHNLAYFYLPFFIVKINKKITGYVTILSLLLFSIGQS"
     gene            complement(593..1489)
                     /locus_tag="LY912_002365"
     CDS             complement(593..1489)
                     /locus_tag="LY912_002365"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBM6956016.1"
                     /translation="MKNKIGIIIVTYNPDNNIKLLVDTLIQEKQNKLIIVDNGSDNIN
                     SFQFEMMENLILKKMNENIGLATAQNIGIEIAKKEKCDYILLLDQDTIIQKNLSLKLL
                     EEFTNIEAKDKDIGIIVPNYFENSNDESVSFTCKNERGRYVKKHFASTSGSMKIAFAN
                     SSGMFFKSELIDDVGNMKDEFFIDQIDVEFCKRVANNGYNIYVTNQVYFYHHVGDGEN
                     LKIGSKKIKIDNHNSTRKYFIARNSTLVKRMYKSDKEFSRLMNKRLLKFFIAIAFETD
                     KLSRFRAAIRGVRDGYRGVIGD"
     gene            complement(1479..2639)
                     /locus_tag="LY912_002366"
     CDS             complement(1479..2639)
                     /locus_tag="LY912_002366"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956017.1"
                     /translation="MSENKKKWLLIHPFDYISRTNILEEILTENSIEYFNVVSDYSHI
                     RKQFLSSKERHMIKNRHVIKTIGYKKNISVMRILSHIWFSIKTLLFIRKEKPEIIYCR
                     IPPNTLVFFIAKFSRCNRVIFDVYDLWPESMPGIGNKYKFFTDLWKKLRDQYLSNSSL
                     VITECDYFKKFIKISGESKNMTIYPCSFNVDDQNDYGEKIVNKSLESTLNLAYLGTIN
                     NIVDLEAINELLKTCKRKFGNKINLYFIGKGESKTKLADICEKNHIEFVDCGVIYDNA
                     EKKVILDKCHFGLNLFKSNTIIGLSLKSIEYFRFGLPIISNLSGDTKEIVKRYNVGIN
                     YNSTVDENEMLKFYQCNKNINENVRKIYATIFSEQVLKMKWNEVYKVMNDEK"
     gene            complement(2632..3246)
                     /locus_tag="LY912_002367"
     CDS             complement(2632..3246)
                     /locus_tag="LY912_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_065828827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBM6956018.1"
                     /translation="MYEKFFKRLIDILFSILGLIMLWPLMTFVAILVRIKLGSPVIFK
                     QQRPGKHEKIFLMYKFRTMTDQRDEEGNLLSDDIRLTQFGKILRSTSLDELPELWNIL
                     KGDMSIIGPRPLLVEYLSLYSNEQRKRHFVRPGLTGLAQVSGRNAISWKEKFEKDIEY
                     VENISMMKDIKIFFLTLKKVIVRDGITSVASGTTEKFEGAKIDE"
     gene            complement(3254..4336)
                     /locus_tag="LY912_002368"
     CDS             complement(3254..4336)
                     /locus_tag="LY912_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_037946024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBM6956019.1"
                     /translation="MSDEGYEQEYVKEAFDTNWVAPLGMNVNGFEEELAEYVGASHAA
                     ALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPIIYQGAIPVFVDSDYETWNMN
                     PEHLRTALEKYPNAKAVLVVHLYGLSAELDEITKICKEHNVVLIEDAAESLGTTYKGK
                     YTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSREKARHYQHNEIG
                     YNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQFMPENNWNEPNYW
                     LSVITVKGINTNHLIDELDKNNIEARPIWKPMHLQPVFDKYEYIGTDVAQTLFEKGIC
                     LPSDSKMTDDDLYRVTNTIKRVMQNV"
     gene            complement(4374..5006)
                     /locus_tag="LY912_002369"
     CDS             complement(4374..5006)
                     /locus_tag="LY912_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBM6956020.1"
                     /translation="MKAIIVGAGGFGKEIAFLLESFSRYELIGFVDDSLKMQNQELVG
                     KTVLGTIDSLLELEEETAIFLGIASPDIKEKIYQKINKNNKLIFPNLVASSALVGINV
                     QLGIGNILMPYTTYTADVVLGNFNMINIGSTIGHDTQIGNYNSIFPSVNISGHVLLGD
                     KNEIGVGTKIIQNLRIGNMNIIGAGSVVIKNINNKTKNVGVPTKVIERWD"
     gene            complement(5017..6834)
                     /locus_tag="LY912_002370"
     CDS             complement(5017..6834)
                     /locus_tag="LY912_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBM6956021.1"
                     /translation="MFVLTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASAASSIIILLFINKQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYLSTDSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVIGFVDDDPNKRNTYLSGKKVLGSLKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSMEELASGKISVSKLKTIDVVELLGRDEVELDIESI
                     KDQITNKVILVTGAGGSIGSEICRQIIQFDPAKLLLLGHGENSIYLIDRELRTHHQKC
                     PTEIVPIIADIQDRKKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPVTVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSMQTVMEFVKSLPQDDEQLAKDIVTFANASNK"
     gene            complement(6847..7611)
                     /locus_tag="LY912_002371"
     CDS             complement(6847..7611)
                     /locus_tag="LY912_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBM6956022.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLQLGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVAQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(7639..8337)
                     /locus_tag="LY912_002372"
     CDS             complement(7639..8337)
                     /locus_tag="LY912_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBM6956023.1"
                     /translation="MARTQKQKATQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSRDAGYYYGN"
     gene            complement(8349..9128)
                     /locus_tag="LY912_002373"
     CDS             complement(8349..9128)
                     /locus_tag="LY912_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBM6956024.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNDKTAPSRRSRSRV"
     gene            complement(9144..9941)
                     /locus_tag="LY912_002374"
     CDS             complement(9144..9941)
                     /locus_tag="LY912_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBM6956025.1"
                     /translation="MERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMM
                     VATVSPEDKQTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPID
                     HYVSINMKGLKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDP
                     NGDYGRQERQRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYR
                     EAFGTIKQDQLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
BASE COUNT         2893 a         2000 c         1584 g         3581 t
ORIGIN      
        1 actttgtcca atagagaata ggagcaagct aaggattgta acatatccag taatcttttt
       61 attaattttt acaataaaaa aagggagata aaaatatgca agattatgga acagtccagc
      121 cactaagata aaaaaaatat acttaaatat agctttgctg cctcgcaatt tagttagatg
      181 ataaaaagct agtaatatga atatcaatgc gctaaacata cgtacttgta ttgcttgtga
      241 agtaaaacca aaaataaaaa acaagaacaa aactaaaaaa acattagttg tgaataatct
      301 gatgacatac aataaagctg agagtaagac agtagaaata atcaataaaa aaatctgata
      361 ctgactggaa ataaaggtac atacgtacat aacagctctg aatcccggtt caatactatc
      421 tgaactaaag tccataccaa attgtgctat cccattatac aagacagaat atgcataata
      481 atcagcgttt tgtgtgttaa atgccatgat gatccacatt atcaaaagta gcaccccaga
      541 caaaatcttg ttcgatgtac tccatttttt ttgtgaaaca ctcttttctt gattaatctc
      601 caatgacgcc tctgtatcca tctcgaaccc cccttatagc cgctctaaat ctactgagct
      661 tatcagtctc aaaagctatt gcaataaaaa atttcaataa tcttttattc ataaggcggg
      721 aaaattcctt atcactttta tacattcttt tcaccaatgt tgaatttctt gcaataaaat
      781 actttcgtgt tgaattatga ttgtctattt taattttttt tgatcctatt tttaaatttt
      841 ctccatctcc aacgtgatga taaaaataga cttgatttgt tacataaatg ttatagccat
      901 tatttgcaac ccttttacaa aattcaacat caatctgatc aataaaaaat tcatccttca
      961 tatttccaac atcgtcaatt aattcacttt tgaaaaacat tccagaggaa tttgcaaatg
     1021 ctattttcat ggaaccacta gttgaagcaa agtgtttttt tacgtatctc cctctctcat
     1081 ttttgcaggt aaaagagaca gattcatcat tgctattctc aaagtaattg ggaacaataa
     1141 tcccaatgtc cttatctttc gcttcaatat tggtaaactc ttctaataat tttaaagaaa
     1201 gattcttttg tatgatggta tcttgatcta gtaaaaggat ataatcacat ttctcttttt
     1261 tggcaatttc aatacctatg ttttgagctg tcgcaagccc aatgttctca ttcatttttt
     1321 ttaaaattaa gttttccatc atttcaaatt gaaaagagtt aatattatct gagccgttat
     1381 ccacgataat aagtttgttc tgtttctctt gtattaacgt atccactaat aactttatgt
     1441 tattatctgg attgtaggta acaataatta tcccaatttt atttttcatc gttcatcacc
     1501 ttgtacactt cattccattt cattttcaat acttgctcag agaatatagt ggcgtaaatt
     1561 tttctaacat tttcatttat gtttttatta cactgataaa atttcaacat ctcattttca
     1621 tcaacggtac tattataatt gattccgaca ttatatcttt taactatttc tttcgtatct
     1681 cctgataaat ttgaaattat aggtaatcca aacctaaaat actcaatcga tttcagactt
     1741 aaaccaatta tggtatttga cttaaataaa tttagtccaa aatgacattt atcgagtata
     1801 actttttttt ctgcattgtc atatataaca ccgcagtcaa caaattcaat atgatttttt
     1861 tcacaaatat cagctaattt agttttgctt tcaccttttc caataaagta aagatttatt
     1921 ttgtttccaa attttctttt gcatgttttc aataattcat taatcgcttc taaatctacg
     1981 atattattaa tcgtacctaa ataagcaagg ttcaacgtag actctaagct tttattgact
     2041 attttctctc cataatcatt ttggtcatct acattgaaag aacatggata aatggtcata
     2101 ttttttgatt ctccggaaat ttttatgaat tttttgaaat aatcgcattc tgttataact
     2161 agactagaat tactgagata ttgatctcgt agctttttcc ataaatcagt aaaaaattta
     2221 tatttgttcc ctattcccgg cattgactct ggccataaat catacacatc aaaaataact
     2281 cgattgcatc tactaaactt agcaataaaa aaaactaagg tattaggtgg tattctacaa
     2341 taaataattt caggcttttc ttttcgaata aataataatg tttttattga aaaccatata
     2401 tgagataaaa ttcgcattac ggatatattt tttttatatc cgatcgtttt tatcacatga
     2461 cgatttttaa tcatatgcct ttctttactg gatagaaatt gttttcttat atgtgagtaa
     2521 tcagatacaa cattaaaata ttcgatactg ttttccgtca gaatttcctc taatatattc
     2581 gttcgactga tataatcaaa aggatgaata agcagccact tttttttatt ctcactcatc
     2641 tatcttcgca ccctcaaatt tctcagtagt cccacttgct actgatgtta ttccatcacg
     2701 gacaataact ttctttagcg ttaaaaaaaa tatttttatg tctttcatca ttgaaatgtt
     2761 ctccacatat tcaatatctt tttcaaattt ttctttccaa ctaattgcat tacgaccact
     2821 gacttgagct aatccggtta aacctgggcg cacaaaatgt ctttttcgtt gttcattact
     2881 gtatagtgaa agatactcaa ctaacagagg acgcggtcca ataatactca tatctccttt
     2941 taaaatattc cataattctg gtagttcatc aagactagtc gaacgcaata ttttaccaaa
     3001 ttgagtcaat ctgatatcgt ctgataataa attaccttct tcatctcttt gatctgtcat
     3061 tgttcgaaat ttatacatca gaaaaatctt ttcatgtttt ccaggtcgtt gttgtttaaa
     3121 gatcactggc gatccaagct ttattcgaac taggattgca acaaacgtca tcagtggcca
     3181 taacattatt aaacctaaaa ttgaaaaaag aatatctatc aaacgtttaa agaacttttc
     3241 gtagatacct ctattagaca ttttgcatca ctcgcttaat tgtattagtt actcgataca
     3301 aatcatcatc ggtcatttta gaatctgaag gtaaacagat acctttttca aacaatgtct
     3361 gagcaacatc tgtaccaata tactcatact tatcgaaaac tggctgtaaa tgcattggtt
     3421 tccatatcgg gcgggcttct atattatttt tatctaactc atcaataaga tgattcgtat
     3481 ttattccctt tactgttatg acacttaacc aataatttgg ttcattccaa ttattttctg
     3541 gcatgaattg tatatttgac aatttagaca attctttttt ataaaaacta tgaatatatc
     3601 gttttttctc aattctttca tttaaaactt tcaattgtcc tcgaccgata cctgcaacga
     3661 tattgctcat tcgataatta tagccaattt cattgtgttg ataatggcgt gccttctcac
     3721 gagattgcgt agcccaaaac ctcacttttt ccaccttttc tttgtcatta gacacaagca
     3781 ttccgccacc tgaagtcgtg attatcttat ttccattaaa agaataaatt ccatagtcgc
     3841 cgaatgtacc agtatatttt cctttatatg ttgttcctaa tgattctgca gcatcttcaa
     3901 ttaaaacaac attatgttct ttgcatattt tagtaatttc atctagttca gctgataaac
     3961 cgtacaaatg cactactaat acagcttttg cgttaggata tttttctagc gctgttcgca
     4021 aatgttcagg gttcatattc caagtttcgt aatcactatc aacaaatact ggaatagctc
     4081 cttgatagat gattggattg gcagtagctg agaacgtcaa agactgacaa atcactatat
     4141 catctttacc gaccccagcc gcttttaaag ctagatgtat agctgctgtt ccagaagata
     4201 gtgcagctgc atgactagca ccgacatatt ctgctaattc ctcttcaaaa ccattgacat
     4261 tcatacccaa aggagccacc caatttgtat caaatgcttc ttttacatac tcttgttcat
     4321 atccttcatc actcatatga ggagatgcta ataatattcg tttattttcc aacttaatcc
     4381 catctttcta tgactttggt aggtacgcca acatttttag tcttattatt aatatttttt
     4441 attactacac ttcccgcacc tataatgttc atatttccaa ttcttagatt ttgtattatt
     4501 ttagtaccta ctccaatttc atttttatct cctaatagaa catgtcctga aatatttaca
     4561 cttggaaaaa ttgaattata attaccgatt tgagtatcat gtccgatagt agagccgata
     4621 ttgatcatat tgaaatttcc taaaactacg tcagcagtgt aagtcgtata gggcatcaaa
     4681 atattgccaa ttcctaactg aacatttatg cccactagtg cacttgatgc aactaaatta
     4741 gggaaaatca atttattatt tttatttatc ttttgatata ttttctcttt gatatctggc
     4801 gaagcgattc ccagaaaaat agcagtttct tcttctaatt ctaataacga gtctattgtt
     4861 cccaatacag tttttcccac taattcttga ttttgcattt ttaacgaatc atcgacaaaa
     4921 ccaatcaatt catatctaga gaaactttct agtagaaaag caatctcttt gccaaatcca
     4981 ccagctccta caataattgc tttcacttta ctccccctac ttattcgaag cattcgcaaa
     5041 agtgacaatg tctttagcca attgttcatc gtcttgcggc aggctcttga caaattccat
     5101 cactgtttgc atggaataac ctttgatgtt tcccacaaag atcttctcgt aaactgcttc
     5161 atcgtttctt tccttatcta acaatagttc ttcatatagt ttttcccctg gacggatacc
     5221 tgtttcaatg atttcgatct cgtcttcgct atatccgctc aatcggatca tgttttttgc
     5281 tagatctacg attttcactg gttcactcat atctaaaata aagatttcgc cgccttttgc
     5341 taacgcccca gattgaataa ctaaacgact tgcttcagga atcgtcatga aatatcgggt
     5401 catacgaaag tctgttacag tgactggccc tccttgagca atttgttccc ggaatactgg
     5461 aatcacacta ccgcgagaac caaggacatt cccaaatctg acagctgaga atttcgtaca
     5521 tccttcttca ttcaacccag tcacgatcat ttcagcgatt cgttttgttg aacccatgac
     5581 gtttggcgga ttgttggctt tatctgtcga gaccatgacg aagtttttta ctttcgctgc
     5641 tttggctgct tctgctacat tttttgtacc gaaaatattg tttttgactg cttcttttgg
     5701 gttatattcc atcaatggta catgcttatg agcggctgca tggtagacga tatctgggtg
     5761 gtattgttcc atgatctcat tgattttctt gcgatcttgg atatccgcaa tgatcggcac
     5821 gatttctgta ggacactttt gatgatgcgt gcgtaattca cggtcaatca agtaaatcga
     5881 gttctcccca tgacctaaaa gtaatagttt tgcagggtca aattggatga tttgccggca
     5941 gatttctgaa ccgattgatc ctcctgcacc ggtgacaaga atgactttgt ttgtgatctg
     6001 gtctttgatg gattcgatat ccaactctac ctcatctctt cccagtaatt ccactacgtc
     6061 gatggttttt aattttgata cgctgatttt ccctgaggca agttcttcca tagaaggcat
     6121 cgtattgact ttcacatgag cagattcgac taactcgaag attcttcgta atttttttct
     6181 tgataaagaa gggatagcga tcgttaccat ttggatgtca tatttttcga tcaattccgg
     6241 tatatctttt aatgacccca gtactttttt tcctgaaaga taggtatttc ttttattcgg
     6301 atcatcatcc acgaatccaa tgacatggat atcttgagcc gttttagaac caagaaagct
     6361 gttgtataaa atacgtccac cttcgccggc cccaacgatc aaggtatttt tagcggaatc
     6421 tgttgataga tacctcatat tttttgtttc gatatagata cgccagatca atcggctgcc
     6481 aatgatcagt aatagcgaaa gtaggtatgc aaagatcact aaacgtaaac tgtattgttt
     6541 atttatgaaa agcaatatga tgatacttga ggccgcactt gcagataacg aaccaaaaat
     6601 cgcaatgatc tctcttaaat ttgtataacg attgattcga gtaaaaactt tgaataaact
     6661 accatagaat aaataaaaac caatcgacaa accgatagag attaaaataa ggtccattgg
     6721 tatagctaca aacggcttca tgaatttagc tgctgcaata ttcgcagcaa tcaacaacaa
     6781 gctgtccaca aataccaatg tggcaatttt tcttcttctt gttaatacaa acaccctaca
     6841 ttccccctaa aataaaccaa acttcttctt ttttacctct tcatagactg gataactgat
     6901 ctcatccccg ttgatcaggt cctttgcgac ttgtttcatc tgtgctactt tttccttacc
     6961 aaagtccttg gcgatttgct cataacattc ttttaagtaa aaggtacgtt tagagacccc
     7021 atgggcatcg gaagcagcca tttgcacgag gttatgtttg accatcattt tggctgtttt
     7081 ctggatgtct tttccaaata caccgacata acttggtgcg gtgagttgag ccaagcatcc
     7141 catatctagg aatggcagca aatgatttgg gtcttctcga aaatgcgcgt tgcgttctgg
     7201 atggacgatc actggtgtct ttcctagttg taacaactca aaaaagagcc attctgcata
     7261 taacggcact tccagtgtcg gaaattcgat tagaagatat gtatcatcta aatctgtaaa
     7321 taaaatttca tctcggtgga tgtcttcaat cagtgttccg gtaatacgta cttcttgtcc
     7381 ttccaataac gtcaaaggca attgtctttt ctctaattct gcttgtaacg aagcgactag
     7441 agaaatgact tgtgattttt cattgctgta ttttccatta ttgtgatggg gtgtgcataa
     7501 aatatgtgtg atcccttgtt gaatcgcttt ttcagccatg gcgatactgg catctatgtt
     7561 ttctgctccg tcatcgattc ctggcaggat atggcaatgt agatcgatca tttctcttgt
     7621 ctcctctctt tttatttctt aattcccgta gtaatagcca gcatctctgc tgtgttctgc
     7681 tccattgtat acaacaccaa ggactcgcgc ttgtaccata tctaacagtt cttttgcttt
     7741 agtcaatgat tcttttcgtg acgtattttc ccgtacgacc aataaggtgc catccgtttt
     7801 tgaagacatg atctgtgcat ctgttacggc aacgactggt ggcatgtcga aaatcactac
     7861 atcaaatagt tgtcttgctt ctgctaaaat ctgatccatt cttggcgaac ttagtagttc
     7921 tgatggattt ggtggtttag gtccacttgg cagaatcgac aaattgtcga ctggtgttcg
     7981 ttggatctca tctgctacac ttcctgatga actaagaaca gtacttaatc cgcttgcgtt
     8041 gttcaacttg aacgttttat agatgacggg cttacgtaag tctgcatcga ctagcagtac
     8101 ccgttgacca gatttggcaa aaacaacggc aatgtttgct gcagtggtgg attttccttc
     8161 tccaggacct gatgaagtca cgacaatcgt tttgatttgc tgaccagctg cggaggcaaa
     8221 ctggatattc gtccggatcg tacgatattg ttcggcgatt ggtgaagatg ggtttgttaa
     8281 tgtgatcaaa ctgactgcat gagtttgagt tgctttttgt ttctgtgttc gtgccatttt
     8341 tcttcctcct agactcttga gcggcttctg cgtgatgggg ctgttttatc gtttgtagct
     8401 tttggtcgtg caggagctga tcctttttta cggataccag cgttcaattc ttttgctgac
     8461 atttctggaa ctgttcctaa gattgggaat cctaatgtat ccgtcacata tttttcatct
     8521 ttcactgtcc gatcaagtaa ttcgaataag aatgccagac ctacgcctac catcattcct
     8581 aacactaagc caatcactag attcaattta ttatttggcg aaacaggtgt cgtattggca
     8641 actgcacctg aaataatcga gattttatcg acattcatca cgtctttggc gttttcttgg
     8701 aaaacttgtg aagttgtatt agcgatctgt tgagcagtca ctgcattcgt gcttattgcc
     8761 tggatcgaga acatttgtga attttgtgac tgattgacgg agatcgcatc tttgatttgt
     8821 ccagcagtca ttttcacatt gtcttctgtt tctaaacgat ctttgacttc atttagtact
     8881 aaatcactga cgatcatatc tttatacgta ttgatcattt gcaggttcgt attgacatca
     8941 ttgacatttg ctgtgtctga ttgtggcagt gtcacgatca attgtgcttg tgaactgtat
     9001 tttggtgtca agatgaaaaa tgttacgatt cctgagatgg ccaagccagc aaacattgag
     9061 atgatgattg ttaccaagtg tttgcgtaat gtttcaaaaa tttctttcaa gctgattgtc
     9121 tcttccattt tttctccact ttcctattta ttctctagat tcatttgatc ttttaattct
     9181 tttttcacac gatcaagttc ttgatcgctg actttttgat aggagatatt atcttgcatg
     9241 aagccttctc cttgcagctg atcttgcttg atcgtaccaa atgcctcccg ataatctaaa
     9301 gcgatttttt tcatttcatc aaagctcatg tctgttttca tattcgactc tagagcattc
     9361 aaaacggatt gatagttgct gacaccgttt aaactcaata ctttttttgc tacaccttct
     9421 acgatctttc tttgacgctc ttgtctacca tagtcaccat ttggatcttc ataacgcata
     9481 cgagaataag ataatgcctg atccccgttc aatgtaattt taccgattgg aaagtcatag
     9541 ccatcttgtg agaaagtgag gtcattattg acttcgatac caccaactgc atcaacgagt
     9601 tcctttagcc ctttcatatt gatagagaca tagtgatcga ttgggatgtc tacatatttt
     9661 tgtagggtat ccatcgccat ggcagctccg ccgaatgcgt aagcgtggtt gatcttgtct
     9721 tttgtgtcac gacctacgat gtcgacatac gtatctcgag gaatgctgac gatcgttgtc
     9781 tgtttgtctt caggactgac tgtggcaacc atcatcgtat ctgatcttcc ttgatcgacc
     9841 cgacctaaat ctccagtatc aatgcccatc aatagaacag agaaagattc ttgtttgtcc
     9901 agatcaactg gtttcgttcg ttctccttgg gttcgttcca ctgattcgta agttttctca
     9961 atagaatgtg agagatccag atataatttt gctcctactc ctacaattgc taatactaat
    10021 acgataagaa ctgctaaaat aatcagaaat attttttt
//
LOCUS       DAFKHN010000088        10046 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFKHN010000088 DAFKHN010000000
VERSION     DAFKHN010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10046
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.088"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(509..733)
                     /locus_tag="LY912_002375"
     CDS             complement(509..733)
                     /locus_tag="LY912_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956026.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            924..3701
                     /locus_tag="LY912_002376"
     CDS             924..3701
                     /locus_tag="LY912_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBM6956027.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            3782..4201
                     /locus_tag="LY912_002377"
     CDS             3782..4201
                     /locus_tag="LY912_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBM6956028.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4213..4683
                     /locus_tag="LY912_002378"
     CDS             4213..4683
                     /locus_tag="LY912_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6956029.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4700..5479
                     /locus_tag="LY912_002379"
     CDS             4700..5479
                     /locus_tag="LY912_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6956030.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5466..6287
                     /locus_tag="LY912_002380"
     CDS             5466..6287
                     /locus_tag="LY912_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBM6956031.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6304..7353
                     /locus_tag="LY912_002381"
     CDS             6304..7353
                     /locus_tag="LY912_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6956032.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7366..8370
                     /locus_tag="LY912_002382"
     CDS             7366..8370
                     /locus_tag="LY912_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6956033.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            9003..10022
                     /locus_tag="LY912_002383"
     CDS             9003..10022
                     /locus_tag="LY912_002383"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBM6956034.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         3367 a         1656 c         2095 g         2928 t
ORIGIN      
        1 tgaaactcta tttacttctt ttttaatttg ttcttgcaat cttttttgct acgtaatttt
       61 tgtaaaaaag tgggttgaga gaaatctaat tgattttcaa agaaggagta tgaaaatgag
      121 aaaaatattt attcgtttat tgtgggtact atcttagagg aataaataat agtggagaaa
      181 actatggttt ggcgcagatt ctatcaggtt tgatggaacg aagacaacct cccgacatca
      241 agtcaaaagc tacttgagat tttgatctga aaataaaaaa agaaaacaag gtaggaacat
      301 caatgtttct accttgtttt cgtaatcaat gggaaaaaac taagagtggt gtacgtaatc
      361 aataaaaagg atggtgacaa cagtacctct ttactctctg aaagcatcat aactcgtttt
      421 tcctcattat gccaataaat tgttgttata ccacatataa ggatttgtaa tagctaaaaa
      481 cagacaggaa agttgaaatc tgtgaatctt attttgtatg gaaggattta tagaacgcaa
      541 aaatcaagat aaagatgaat aaaaatcctg tttcggctat atattgcgta tctacgccaa
      601 taaaacgagt ttgttctgtc atagccatat aaagcaaagg caaaaataca actacagcga
      661 gataagatcc gatgatttct cgaaaagttt tccaggaagt atgtttcctg tttttatatt
      721 tatccgattt cattgaatag tcatagcctc cttattcttt catatgttga aattccagta
      781 taaaaactgg aaggaactgt acgtttttta gaataaaaat tataagggat aagtaggctg
      841 ctgtctataa taagatatat ttttcaattc tttattaaag attttattga caaaatgaat
      901 ccgttttcta tgatggagga ggggtgaata agttgttgaa gaaggaaatt ttatgttact
      961 tagagaacca gacagccttt ttcgatttag aacatatgaa cgaggtcttt acagcacaaa
     1021 ggttagctga tcattttggg gtaaaaagaa acacagtcag tcattatttg aaccagttaa
     1081 atgatgagca actactagtc aaaatcaatt ctcgaccagt gatttatttc cacaaagaag
     1141 cttttgaaaa acaatttttt aagttacgca cgaattttta tttttctatc gatgatctca
     1201 aagaggaaca gccttttttc gcgcaaccaa aagacttatt ctcttttatg atcggatacg
     1261 acgccagttt gaaagaaagt atcgaacaaa tcaaaacagc tctttactat ccagatggcg
     1321 gattaccact tttgattaca ggcgaaagtg gcacaggtaa aagttattta gttaatttgg
     1381 tctatcagta ttgtctgctt catgatctgc tagaagattc tgcaccattc atcactttta
     1441 attgtgcaca atatgcagat aatcctgaac ttttgactag caatttgttt ggacatgtta
     1501 agggagcgta cactggtgca gaagaaaata aaaaaggggc ttttgaagca gcagatggtg
     1561 ggatcttgtt tttagacgag gtacatcgct taacaccaga aggtcaggaa aaactgttca
     1621 cctatcttga tcaaggtgtg atttatcgta tgggagaacc taatttgtca cgccggatca
     1681 aaacacgtct cttttttgct acgactgaag agattactag tcatttctta acaactttca
     1741 ttcgaagaat acctatccga atcgaactac ctgcacttaa tcagcgtagt cgtaatgaac
     1801 ggctagaact gatttactct ttttttctcg aagaacaaag aaaaatgggg agccctttgt
     1861 cagtcagtgg accagctttg tcacttttaa caagtcagaa attatccgga aacataggag
     1921 agctgaaaaa tatcgtcaaa gtttcagcag caaaagcata tgctgaacag cgtgaacagc
     1981 ctgaaatcca tgtcacgatc catcatttgc aaaaagaact acttgcgcag cctattacta
     2041 aaaatacagc acagcaagga atctatatta cgcaagacca gaccttagag caattaatgg
     2101 agaagcaaca gcccgaacag cagcgaatcg ttaaaagttt tgagcaaatc ctaattgatt
     2161 tcaagaaaaa taactgtctg ctatattctt gcgaaggaaa attaaagcaa gaagtgattc
     2221 aattatttga ttttttgctg tttgagacca gtagacaaga aaaacacgag ctgctggttt
     2281 attggacaca atctatccga gagacctttc gacaaatgga aactgcctat caaatcaaat
     2341 tcgatggaaa cagtgtctat gccttgagtt actatctcta tcagcgaagc actatcaaat
     2401 ggttaccgga agaacatgat attatccaac taatcaaaga attagaacaa caagtttctc
     2461 agtcttatcc atctagttat cactatgtcc aacgaattct ggaattaagt aagatcaaat
     2521 tagatattga agacacaagt atggatcgga ttttactgac gatctatcta aaaaaagcga
     2581 aatggtcaaa agaaaaacga ctgccaaaag cgatgattgc tgctcacggt tatgcaactg
     2641 ctagcagtat ggcaaatgta gtaaatcgtt tattacaaga ggatctattt gaatcatttg
     2701 atatgccact agatgtcaca ccacagcaga ttgcttcaga aatccttgat tattgcgaaa
     2761 acagcgatgt ttcaaatgga ttgatcatat tagtagacat gggatctctg aaagaaatcc
     2821 atcagttttt taaaaaacag ttatccgtac cgcttttgat tttgaataat gtgacgacac
     2881 ctttagcaat cacagtaggg gaatgcctgc aaaaaaatgt atcattagaa gagatagcag
     2941 aagagactgt tcgacagatc cagccagaat ggcgactgct ctatccagag gaaaacaaac
     3001 ccaaagcact cattactact tgcttcactg gaatcggtac ggcggtccac ttaagtgaac
     3061 tgctagaaaa aagcttacct acggcttgtc agttgaaaat catcccatat gaatatcagc
     3121 aattaaaaga taagaaaaac agtgacccat tattttccat atacgaagtc gtaggaatga
     3181 ttggcaccac agatcctgat atcaccaata tcgactatct ttcattagaa gacctcatct
     3241 cgggggaaaa gatgtctgta ctagctgaat ggttggacac tactatgaat gcttcagaga
     3301 aggaaatatt caatcagcgc atcattcgta atttttcatt ggaaaaagta ctggattccg
     3361 tgactattct agatacagag aaggtgatgg gagaaatcga tcattttatg agagaattag
     3421 aggtgcagtt gaatcgaagc atcagcaatc ccaaaaaatt agcgttgtat gtccatgtga
     3481 gctgtctcat tgaacgattg atccgacaaa tgccaatcga aacctatcaa ggattagaga
     3541 aatggaagca gtgtcaaaaa gaagggttat ctgctattaa atctgcgttt agtgtcattg
     3601 aagagcatta tagtgtcatg atccccaatt ctgagattgc ctatatctat gatattttga
     3661 gtgaagatac agagtttctc tcgatagaag aagaattttg aacataagca agttgttgcc
     3721 actaattttg gcatgcaact tgctttttta gtatgtgtaa gtgaaaagag gagatgaaaa
     3781 agtggataga gaaattatct tagcttccca tggaaaattt gcttcaggga tattagattc
     3841 attagagctg atctatggga aaaatcattc tattactgta ttcgattgct atactgatga
     3901 gaattttgat ttagcggaaa cagtaaggca gctttttatg aggtacaaag ataaagaaat
     3961 cattgttctg acggatcttt ttggcggaag tgtcaacaac gaattcttac aatatatcaa
     4021 tcgggatcat gtctatctcg ttgccggatt gaatttgcca ctattgattg agctagtatc
     4081 tcggttggac gctgaagtag agacaactgt tttgatccag caggtgctaa ctgattcaaa
     4141 aaaaatgatc cagttttgta acgagcggct caatcagaaa atagaagaag acgaatttta
     4201 ggaggaagaa aaatgattgt attgacaaga gtcgaccatc ggttattaca cggacaagta
     4261 gctttttcat ggacacaaac aataggcgca gactgtattt tgattgctaa tgatgatgta
     4321 cctacgaatg agatacgaaa gacaacgatc aaattagcca agccacaagg agtcaaacta
     4381 gtgatcaaat caattgatga ctcgattgcc gcgttgaaaa gcggggtgac agataaatat
     4441 aagttattca tcgtagtgga atcgatcgag gatgcatata agctggcaga agcgtatcca
     4501 gaaatcaaaa ccatcaactt aggagggatc aaggcaaaac ctggtactcg cagcatcgga
     4561 aaagcggtaa atattttacc agaagaggag gaacgcttga aacgattaat tgacaaacaa
     4621 atagaagtag aaatccgtca agtaccagca gataaaaaag tggatgtaag agaagttttg
     4681 taagaaagga agaacctcaa tgattgtaca agcagtctta ttaggaattg ttgcatttgt
     4741 cgcacaatca gaatatgcac tagggacatc gttgctttct cgtccgattg tgacggggct
     4801 gtttacagga atcgtgttag gtgatgtaaa aactgggatc attatgggcg caactttaga
     4861 gttagcattt atcggatcgt tctcagtagg tgcttcgatt ccacctgatg ttgtgaccgg
     4921 tgggatttta gggacggctt ttgctattac agctggagcc ggtacagaaa ccgcgctttt
     4981 actaggtttg ccgattgcta cgttgacatt gatattgaaa aatatttact tagggctttt
     5041 gattccaatt atgaaccata aagcagacaa ttatgcagaa gaaggaaatt ataaaggagt
     5101 cgagcatatg cacttgcttg ccggtatcgg tctttccttg atgcttggtg ttgtggtaat
     5161 ggtttcttat atggtgggaa gcaatacgat cggaaatcta ttaaatatga ttcctgactt
     5221 cgttcaaaag gggttgtcag tagctacagg gttgattcca gctcttggtt ttgcgatgct
     5281 tgctcgtttg ctgatcaaca aacaagttgc accatatttt ttcttaggtt ttgctatagc
     5341 ttcttactta gagattcctg tgaccggagt agctattttt ggtgcgattt tagcagttgt
     5401 ggtagtcaat attatgaatg tccgtcaact accacttcaa acaactgcag gggaggtaga
     5461 agaagatgaa gaattctgag atcaaaaaca gcaaaataac gaaaaaagag ctaaatcacg
     5521 tattttggcg ttcttttcaa atggagtttt cttggaatta tgaacgtcag atgaatatgg
     5581 cttatgttta tgcaatgatt ccgattttga aaaagttata tcagtcgaaa gaagaaatgg
     5641 cagcagcttt gaaacggcat ctagagtttt ttaacacgac cccacatatc gttacactga
     5701 ttttaggaat cacggctgca atggaggaag aaaataagga tgatcctgaa tttgatgtga
     5761 ctgcgatcga tagtatcaaa acatctttga tgggacctct tgcagggtta ggagattctt
     5821 tcttttgggg aactttgcga ttgattgcca caggtgtggg tacctcttta gccatgcaag
     5881 gaaatatttt aggccctatc ttgttcattt tgattttcaa tattccgcac attctgtttc
     5941 gctatctagc aacaggttgg ggatatcgct taggaacggg ttttttgaaa aagatccagg
     6001 caaacggtat gatggaaagt ttgacattag gcgcgtctat tattggactg atggtcgttg
     6061 gagcaatgac tgccacgatg atcaccatca atattccttt aaaaatcggt tcaggagaaa
     6121 atgctgtgac tgttcaaagt atttttgatg atatcgttcc aaatatctta tgtcttggag
     6181 catttggcat agtgttttat ctattgaaga aagaagtgaa accattaacg atcttgatcg
     6241 gactagcttt ctttggaatt tttggttcgt ggatagggat tttttaaaaa aggagcagag
     6301 aaaatgttta cgatgcaaga ttatatctat gaagaaaagg aagtactaag tacgatcttg
     6361 aaaaagaatg atttttcgac aagagaacat atgaaaaaaa cagtgaattt actgatctta
     6421 gcaacgggtt catcttataa cgcttgttta gcagcgaagc cagcattgga atcttatggt
     6481 gatcttactg tcgatattca agaacctttt tattttttca attatggaaa actttctcct
     6541 tcaatcgata ctgtgattgc tgtgtcacaa agcgggaaaa gtgcttctac tgttgaagca
     6601 gtaaaaatga tacaaaaaca agggttacct gttgttgcta tcacaaatga cgtgcaaagt
     6661 ccacttgctt tagaagctgc acaaattatt gatttaggtg ccggggtaga atcagtaggc
     6721 ttcgttacaa aaggctattc tgcgactgtt ttacagttac tactcttagg gataggaatt
     6781 ggaataagta aaaataaaat cagcaaaaaa atagaacaag actacatgca acagttgcgc
     6841 aaaataatca accatttacc agcgattatt caaaaaacgg aagaattttt tgatggatat
     6901 caaagtttat ttcgtttagc acagcgtttc gtcaccattg gatatggtcc aaactgggga
     6961 acagctaaag aagcagagac gaaattgact gaaacaatcc gcgttccgtc acaaggattt
     7021 gagttagaag cttatatgca cggcccatac ctggaggcag atgcttcgca tttgctattc
     7081 tttattgaag gggaaagtgt aaataaggaa cgttcgcaaa agttgcaaag atatatgagt
     7141 cggtacgttg gagagactct caccattacc acaaaaaaag caagaaacga gaaaacactt
     7201 ggattagcaa tagaatgtga tgaatatctg tctgtattag cgcttgtcgt tccgtttcaa
     7261 ctattcgctt ataaaaccgc agtagctaaa ggtattgact tgaacaaaaa gatttttgaa
     7321 gactttgata cagtcttgaa aagtaaatta taagaggtgg aaatcatgct gaaattcaat
     7381 gaagaagaac aaatcaaagc aataaaaggc gcactagctt tacgtccgca agtagaagaa
     7441 atcatcgata aactttatgc ggaaaaattt gacgctgtct attatctagg aatcggtgga
     7501 acgtatgctt cctcgatgca agctgtcact tatatgaatg ggaaaagcaa cttgcctgtc
     7561 tttgtacagc atgctgcaga atattacact actggaaaca aaagattaac aaaagattct
     7621 atcgttattt tgtcctctgt taccggtaca actcaagaag tagtgaaagc agtagaacaa
     7681 atcaagaaag taggagcgac actgattgga tttatcgata aagcgaacag taagttgtct
     7741 cagctatgcg attttgtggt cacttatcca gctcctggaa cagaacaaat caaatttttt
     7801 atggcagcag atcgattgat gtatttgaat ggagaattcg aagcttattc agaatactat
     7861 gaacagctcg aacgttattt accaacaggg ttagtggaag cagagaaaaa agcagatgca
     7921 tttggcttat catttgcaga aaaacatcga cgtgatagta tgcattattt tattggagca
     7981 gggaatcaat ggggagctgt ttattcatat gccatgtgtt actgggaaga acaaagctgg
     8041 cttccatcga aatctatcca tgctgccgag tttcttcacg ggacgttaga gatcgtagaa
     8101 gaaacaaccc cagtcacatt atttttaggc gaagatgaac agagagtgtt atctgaacgt
     8161 gtggctaaac ttttgccaaa aatttgcagc aattatacat tgatagacac aaaagactat
     8221 ccagtagaag gtatcagtga aaaatatcgc ggacgtgttt tgtctttctt attgatgcat
     8281 gtagtgacac aacgcatcga tgctcatgtg gagcagttga actgccatcc attagagata
     8341 cgccgctact atcgtcagtt tgattattag gatagactgg ataaaaagaa tataaaaaat
     8401 aaagagagca gcgataactg ctccctttat ttttttaaaa tattggcatc aattacgtta
     8461 taaaacacat tttttgcatt atctacagtt caacttataa tctgtttaat gggacatgtg
     8521 ggtgccaacc attttttgtt atgcaatagt actatttagt tgttgcatgg atccgtagta
     8581 aaagtccaag tacaacgagt tgcgccagtt tacatagcgt tttgtatcca gaatgttgac
     8641 taaaacaaaa gttcctatgt caaccgtcaa cagagacaat ctgtccgttg caggacctga
     8701 cagatttaga aatgttcaat ctgtctctta tgtattttaa atcaatactc actaggagaa
     8761 gtttcctaac ctcctaatag taatgctggt agtaacattg tcaaaactgc ttcctcttag
     8821 gaacaagcaa agcataacga gtgtaaaaat aaaatgtaga ctattgtaac atatcattga
     8881 ttatttcaag taaaaacgat aaaagaagta aacaaacact taaaaacaat ggaaattagt
     8941 cccaacttta agaaatgtat actataatgg aaattatcaa ttatttattt ggaggaatat
     9001 ccatgaaaca aaaaatcgca gttcttggtc ctggatcttg gggcactgct ttagcacaaa
     9061 cattggcaga aaacgggcat gatgtccgta tttggggaaa tgtacctgaa cagattgatg
     9121 aaatcaataa gtatcataca aatcagcatt ttttacctga tttgacgatc ccagaatcga
     9181 ttatcggata taaagaattg gcagaagcag tggataacgc agatgctatt ttatttgttg
     9241 ttccaacaaa agcgattcgt tcagtcgcac aggaacttat tggtaaaatg aatactaagc
     9301 caatcattat acatgcaagt aaaggactag aacaagatac gcataaacga atctcagaag
     9361 ttttggctga agaaattcca gaagaaaaaa gacaggcaat tgttgtatta tctggtccta
     9421 gccatgctga ggaagtggca gtacatgata tcacaacaat tacagctgca agtattgatc
     9481 aaaaagcagc agcctatgta caaaaactgt tcatgaatga ttatttcagg atttatacaa
     9541 ataatgatgt gattggcgta gaaactggtg cagcactgaa aaatatcatt gcaattggtg
     9601 ccggcgctat ccatggatta ggattcggag atgatgcaaa agcagcaatc atgactcgag
     9661 gattggcaga aatcagccgt cttggtgtcg cgatgggtgc caatcctctg acatttatcg
     9721 gtttgagtgg tgtgggggac ttgatcgtta cttgtacaag tgttcattct cgcaattggc
     9781 gtgccggtaa cttgttagga cagggacata agctggaaga agttctagaa aacatgggaa
     9841 tggtcgttga gggtgtggca acgacaaaag cagcagtaga gctagctcaa cagctaggtg
     9901 ttgagatgcc aattactcaa acaatctata atgttttgta taatggagaa gatatcaaaa
     9961 aagcagcaaa agaaatcatg ttacgtgacg gaaaaatgga gaatgaattt tctcttcgtt
    10021 aaatagatga tcaatagtta atcgtc
//
LOCUS       DAFKHN010000089         9806 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFKHN010000089 DAFKHN010000000
VERSION     DAFKHN010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.089"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(409..666)
                     /locus_tag="LY912_002384"
     CDS             complement(409..666)
                     /locus_tag="LY912_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBM6956035.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(659..928)
                     /locus_tag="LY912_002385"
     CDS             complement(659..928)
                     /locus_tag="LY912_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBM6956036.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(1059..1238)
                     /locus_tag="LY912_002386"
     CDS             complement(1059..1238)
                     /locus_tag="LY912_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956037.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(1619..2326)
                     /locus_tag="LY912_002387"
     CDS             complement(1619..2326)
                     /locus_tag="LY912_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956038.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(2319..2756)
                     /locus_tag="LY912_002388"
     CDS             complement(2319..2756)
                     /locus_tag="LY912_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956039.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            complement(2771..3022)
                     /locus_tag="LY912_002389"
     CDS             complement(2771..3022)
                     /locus_tag="LY912_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956040.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            complement(3022..3228)
                     /locus_tag="LY912_002390"
     CDS             complement(3022..3228)
                     /locus_tag="LY912_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBM6956041.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            complement(3665..3925)
                     /locus_tag="LY912_002391"
     CDS             complement(3665..3925)
                     /locus_tag="LY912_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956042.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            4000..4203
                     /locus_tag="LY912_002392"
     CDS             4000..4203
                     /locus_tag="LY912_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBM6956043.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            complement(4344..4829)
                     /gene="ssb"
                     /locus_tag="LY912_002393"
     CDS             complement(4344..4829)
                     /gene="ssb"
                     /locus_tag="LY912_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBM6956044.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(4832..5731)
                     /locus_tag="LY912_002394"
     CDS             complement(4832..5731)
                     /locus_tag="LY912_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBM6956045.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            complement(5744..6337)
                     /locus_tag="LY912_002395"
     CDS             complement(5744..6337)
                     /locus_tag="LY912_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBM6956046.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            complement(6413..6562)
                     /locus_tag="LY912_002396"
     CDS             complement(6413..6562)
                     /locus_tag="LY912_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956047.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            complement(6578..8782)
                     /gene="topB"
                     /locus_tag="LY912_002397"
     CDS             complement(6578..8782)
                     /gene="topB"
                     /locus_tag="LY912_002397"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBM6956048.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            complement(8793..>9806)
                     /locus_tag="LY912_002398"
     CDS             complement(8793..>9806)
                     /locus_tag="LY912_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBM6956049.1"
                     /translation="ELKPKYERQNFLVRDDRLDHAVAFLWKDPQTKETVGASYQGTFI
                     DYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLNDTW
                     LVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDP
                     FTNQKVRCERGIANDWQVPKEYKIIYEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVS
                     AHKVNAFFGQQLSVNDSIEAINLKDICREVAKELKVCERVDGTYDFDRFYQEKGDINA
                     QILFSYKAEQYYKGYKNHEHEFIPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQ
                     ERE"
BASE COUNT         2572 a         1995 c         1622 g         3617 t
ORIGIN      
        1 tgtaaataaa tcattaattt ttagctaaat tctatgagaa gtttattttt gttgtttttg
       61 ctaattaact aaaactagta caaaaaattt aaaatagatt attaaaccta ttgcttattc
      121 tattcagtca tatatataag cgtcatcctt tagtaactaa catcccacac tacaatagta
      181 ttataacata tctattcaac ttcaaattgt tgaaatttaa gccatttata tttacttttc
      241 ctcaacttta gaaatgattt tactaacctt atatccgtaa tacgcgtaac aaacacattc
      301 attaataaca atcaacacta agctatatta gctttttaaa tgactagggt aaataaaata
      361 aggatcaaaa acttttaagt ttctgaccct ttccttactt ccgattggtt aatagtgatc
      421 ttttgcagaa taaataaata tcgtttcatt ttcaactcta tatatcagtc tatgttcatc
      481 tgtaattctt ctggaccatt ttccagataa atcatgcttt aatggctcag gttttcctaa
      541 tccagcaaag ggggaacgat cgatatcttt tattaacttg ttaatctttt ttatattgct
      601 tttgtttcct tgctcatgcc aataaagata atcatcccaa gcatcatcag accaagcctt
      661 aatcatcaga ttcaacctcg attaagtcat gtgttttaaa tgcacctttg gagaattgtt
      721 catctcctcg acgaattttt tccatgacgt aattattaga aagtgttctc aacgtttctt
      781 gcatagaatc ataatctctt tttgataata caacaactgt atcttctaca tctttacttg
      841 ttacaataag tgtttcagca tcctcattaa cttgtttcat ataactacgt aaattttggc
      901 ggaaatttga ataagctact gcttccattc ctttcacccc ttatttattt ctataaaaca
      961 attgtacatt atattgtaca attaagcaaa tgattaatat tctaacttct tataattaaa
     1021 agtgctatca cttttagttt ttaggataaa aagtgacgtc actttttgag tgctggtacc
     1081 tcaaatcctg ctttttcttg ggcaatcaat aaatctaacg caatacacat aatcctggat
     1141 tcacttttgc cgtacttctg ctttagttgc tgcaattctt tttgtctctt ttcatccaac
     1201 gtcacgggta accgtttatt tcctattgca attggcatta gtactctctc ctttcatcga
     1261 aataacccta ttaaaaatat ggctgcaatc aacttgaata ttagactcac aagggttaac
     1321 acaaagcgcc aaaagatcaa acaaaatacc agtattccta agaatactac gaagtttaaa
     1381 tgtagagctg caccatgacg cataagtatc tcgccaacaa acagtacgaa caatagagga
     1441 atgattttat tcatatggat ctccttcttt ctcttaggtt atcgggcttt gcccgcttat
     1501 ttcgcaccac ctaagcggcg ggggcggttg gatcgattgg tgcgaaataa gaaccattcc
     1561 cttaatttca aggttttttg ttcttatttc acacatcctc acttttcggt ataaatggtt
     1621 attgaccttt tttcctttca aatcgttgat atggcattcg tttacggtca agttcatttt
     1681 ggatttcttc tgtatcgtcg taagtgtagg tgtctaaaaa atcagttaaa gtcgtgtacc
     1741 agtcgtcgcc tgggttatct acttcttcta catattccct caaaaatgct tcgggtacag
     1801 tgagttcata atccattccc attaacacga tagattccgt cccacacgtc aaaaatctag
     1861 taaatacaag gtaataatcg tctaccgtcg catctttgct gtttagctct tccatttctt
     1921 cttccattaa ttccatgctc tcaaaaattg aataatattc tgattctgag taatagtgtt
     1981 tcctgcaaat cgtgtagctg acaaagtttt cgaccagctc actcctttct aggtaaacat
     2041 tcatgatata tttttctgtt tctagtcgta gaagctccgc tccttttttt aatgtgtcag
     2101 gacgacgttt atacacgtct aaacgattat ggctgactgt aaccttcgtt tgactcgttt
     2161 cactttccat atacaactgt tcttccactc tttgaataaa gtacttcatt tcttccatac
     2221 aactaaagtc tttttgaatc cgtctgatta cttcattcaa gtgttctttg tttgttaaaa
     2281 attgcgaaac atcttctgtt gttagctgat aaaccacctt attcattatc tttctcctcc
     2341 gattcaatcg tataaaatgc accatttttt tcgatatttt caaaagtatc tagccagtcg
     2401 ctagccattg ctttagcttt cttaatctgt gcgaattttg cataagtcag ttctaaggct
     2461 tgatattcgg aaggtttgat agtgcttggt ttgacaccta cttccaagca tagtaaggct
     2521 tggaaaaacc attttccatt ttgttttttc agttcttcca gtgttcgata gtacgtcgca
     2581 atgagattca tttcgacacc tgattcaatc atttcttcca ctgcgactga caatttttcc
     2641 ttgtaatgtt ttttgggtac acgtgtttca tggtatagga acgtcatatc ctccattttt
     2701 tgtgccattt tatccaaagg taatttgaca aattcgtcat agtaattttg agccatattt
     2761 tttctccttt ttagttctct aatttggtta accaatattc gatttcataa gtttccatgt
     2821 tttcttgata atgcagttca tatcctgcaa tcttcactag gtcttcaaat agcatagtcg
     2881 gtgcatcctc tactaaaggg gtttctatcg tccagtaccg cggaataagt aaagcttctg
     2941 ctactttttc agaaatgact tctttgtcca ccaaaatttg aacgacttct tttacagtca
     3001 ataatttgtg ttgtgttttc atcaccgttt ctttactttc tcatcaatca aaacataatc
     3061 gccataagac aaggtatatt ttttcccgca tgttggacat tgatacaaac gatagctttt
     3121 gatacatttc gctctttctc cacaatcgca ttcgacagta tgtggtgcat gatagtttgg
     3181 gaataattcg ctgaagggaa caccccaata atcaaatttc tttcgcatga ttgattctgc
     3241 ctcctcttag gaaaggtttt atttcctttc gttagttctt tctttattga tttgttggcc
     3301 agaatgaatc aacgaaaagc gacaaggaca agggcgcgca gcgtgccatt tacccttgtc
     3361 cttgtcgctt tttggtgata aaaggcaact tgttgccggt ctggcaaatc aataaagaga
     3421 tagcgaacag gaacgaacct tttggtgaga ggaagttttt tctattttgt cttgctttgc
     3481 aagacaccat atcttagtga acgtgcaacg ttcacttcct ttcttctcga acggcggtgg
     3541 cggttggagt gagagaaagg tttttcaatt gagaaggcac ttgtgtcttc ctaaaaaggt
     3601 cttttcctgt ttctatgtaa aacaaaaaga gctgcaatcc tcatttagga ctgcagctct
     3661 tcttttatat gcccatcgat cgcgtaaaat gatcggggtt tctaatttgc atcgattcaa
     3721 tgactaattg attccgttta ttgaaatgac ctgtgacggc aatattgtat tttccatcat
     3781 ccataattaa caatttatcg ataatttcaa tatctgcaac tacacaatta atcgattcat
     3841 gaattgtttg taaagtaaag cgaaccaata atggttgtgt ttttattact cggattttat
     3901 caagcaaacc aacatatttg ttcatcacga tcacctcgct aaaattatag caaaaacagc
     3961 taaaattgag aatttttatt cgattttaga tatgctataa tgatcaagac agtaaagttt
     4021 gtgacggtgg ctatccgatt gaaagtgagg tggtgcgtat gtgcgtactt ccaaaatctt
     4081 acagaaagga gaagcctttt gcctgttgaa acggcgctag gattaatgat tagtttcggt
     4141 tctttgatcg caacaatcat ttttggaatc ttagcagttg taaacaacaa tcaaaaaaaa
     4201 taaccgtcag ctttagccgg tcgacgatta tttttcaaaa ataatattaa gctggtcacc
     4261 gtcttaaacg gtgctgttag gggagttgtt agcgcaactc ctcttttcgt atccattata
     4321 acaactttat tgatctttta caatcagaat ggtaaatcat catcactaat atcgattgat
     4381 tgtccgccaa atggattttg tgaagcgttc aatccattgt tgttaggcgt agctacatcc
     4441 cgttgttcaa aggtggtagg gcttggactg ctggacgatt gatcagcgtg cgcacggctt
     4501 tctgtcgctg ctttactttc taatagttgg aaattatcgg ccacaacttc tgtcacatac
     4561 acacgttgtc cttgttggtt atcgtaggtt cgggtttgaa tccgtccaac aacgccgatc
     4621 aaactgccct ttttagctaa tgtcgccatc gtttctgctg gtttgcgcca aatcacacag
     4681 ttaataaaat cagcttctcg attgccgttt tgattcgtga aatttcggtt gacagctagg
     4741 gtaaaagtcg ctactgcagt accactcgcg gtataacgta aatctggatc tttggttaag
     4801 cgtcctacta aagttacatt attgatcatc tttatctctc catttcttga ttcatttgtt
     4861 gtgatctttt aaactgccgt tttctttctt gattttcaat tttgatcaca cttttcatta
     4921 ggtgatcaat ttcgttgact gtatctgtaa atgaaatgga attcgcaaac gtgttaactg
     4981 agcgatattt ttcccactgc ttttccaaat agtcatttcc tctgatctta tccatttctc
     5041 tttcataata aaaggacaac ggttttgtat ccccacgttt tgtaaatgta tttcgaacac
     5101 ttttgtataa ctctttcgta tcgatatttt ctagtttcgg aatggtaaat aagtcgtagt
     5161 aatcttttgc tctcgaatta tctgtgccaa agctgaacgt agcacttagc ttttctgcaa
     5221 taatttgttc tgttggataa gctggaatct ccactttttt atcttcaaac attaattggt
     5281 gatagtgtgt atctacttca ggataaatag aatctcctgt tgtcacgtcc attttaaacg
     5341 gtacacgtac tttctctaaa ttagccacca atttaatttg aaatccagga taaaaatcgg
     5401 cttctcttgt ttccttcatt ccttgaatag agaaaacaat gccttctttt gtgggttttc
     5461 tagttaaatc attaaaaatg ctcttcaatt tttcttcagt taatttgcta tttctaaatg
     5521 tcgtatcgat atcaattgtt gtccttctat cgattccata ttttgatcct aataaaaagc
     5581 cgcctttcaa aatgaagtca tttttgtact ttgattcaga aatttgttca attagacgat
     5641 ccatcataaa atgccgttgc actaactgtg catttaatcc tgtactcttt gctaaatttc
     5701 ttgtttttgc tgcaaattgt gtcggtgtca tctttttcct ccatcaatat aagctttgca
     5761 tgtggtattt catttctttt tctacatgta gttttgtcat gtaatctctt aatttacttg
     5821 gatctctcaa tgggtcttcc atgtactctt ttaatgcttc taatttcatt tcatattcaa
     5881 attcatatct cggattccaa atatcacaaa gtgtacgctc tttatcatac atagtaatag
     5941 gatttccttg aaaggaagtt ccctctactt ttcctagttc ataaacttct ttcttcacga
     6001 aatgaaattg taactgctgc tcttttgtaa ttgaacgatc aacgttatag ccatggggaa
     6061 aagttaagtg aatgaatttc ggcatattcg tagaaagctg gtaaatatct aaagtcgttt
     6121 catgagagaa gattcccctg gaaaatcgtt gctgaagcca aaataaatca tctattccat
     6181 gaccatcctc tacataataa ccacgatcaa ctttgatcaa ttttccttga ttcaccaatc
     6241 tttgtacagt ggttgctgcg attccaaatt tcctggcttc cttcatagat aaatttccat
     6301 cgcgaatagc caacaattct ttcagtttat cttgcattta cttcccctcc cttcgttaca
     6361 aatacactac atcaaatata tcatagtagt ttatttgtaa caagattaac gtctatcgat
     6421 ctaattcgat ttctttttga atgcgctgct ggttctttaa ttgttgcagt cttcttttat
     6481 ttgcacgtaa tttctcttgt tctaaacgaa tttttgcttt ttgattttcg atttcttgtt
     6541 gtttgtgtgt tgtatttcgc ataggataac cccttcatta ttttgtagtg cggcgtgttc
     6601 ttttcttata gttcgttttt ttcttttcag aaaattcaaa gcctgttgta aagtcttctt
     6661 ttaaaacgat cgttgcttca aacgaacctt tctgaccttt tagtcctctg actgattggc
     6721 ttgttcggcc gttttgaatg atctctttca gttgtgtggc tgtgagtttc tttttggcaa
     6781 tcgttgtcca taatttaaaa tcacaggctt cagacgtaca tgccgccaca ttttgataaa
     6841 gcaagacttc ttgttcccga cattttggac aaacacctaa atgacgcgtt gcttcctgtt
     6901 tttcactggc tgctttcact tcttgtaacg tcgatccaaa atcagtggat tggatttgcc
     6961 ctggtacgac ttccaataag tgagagacaa atttttggat attggctaga aaagtggttt
     7021 gtgttccttt tcgttcaccg atctttaaca agtagctttc ccatttggcg gtcatttcgg
     7081 cactcgtaag cagcggctct ttttccacgg cttggcaaag caaaatccct ttattcgtca
     7141 ccacgagctt atttttctct accttgatat attccttttg tttcaaggtt tcaataatat
     7201 tcgcccgtgt cgcttctgta ccgattcctt ccacttcttt caatatggat tgcgcttctt
     7261 cactatcaac ggttttccca gctgttttca tcgccgtgat caacgtacct tcggtataag
     7321 gctgtggtgg cttggtttct ttttcaagga cttgtagatc taccgtcacc atttctcctt
     7381 ttgtcacttt aggaagtagc ggctcttctt ccttctcttt tccgtcgttc tctttgccaa
     7441 ataacttctt ccaacctaga tctatcggta cttttccgat tgcctttaac tgaagctgct
     7501 ggacttgcgt caagatcgtt gtttcttcat aggtatattt ttccgcaaac atggccaccg
     7561 ttgtttttaa cacttgttca taaatggcct gctgcagtgg acttagttgt tcaaaagccg
     7621 ctgctgtcat aaccgttttt gtaggaatga tcgcgtaatg ttcctggact ttcttgttat
     7681 tcacataccg actattcggc gtatgaatag gggttgggat tgattcggcc tttaaaaaat
     7741 gcttgtattc atctaaatga tccaacaaat acgcatactc cccttccgta atataagggg
     7801 tgtctgttcg tggatagctt agatatttcc cttcatacaa gccttgcatg gcttccaaag
     7861 tgtctttggc actagctttc atgagctgat tcattttaga ctgaaggctg gatagagaaa
     7921 aaagacgtgg acttgccgcg ctttttttct cggtttcaac ttggcgaatc atgcctggct
     7981 gttttcccaa ttgaaccccc ttttctttta aataatcttc aaatgcttct tgcgtcgctt
     8041 gggtttcatt cggatcaagc ttcgcatcaa atgcgccatt ttgagcgatt acttcggatt
     8101 ttccttcaaa ataaggttct ttcttgaaat ttctaatctt ttcctgcaat tgataaatca
     8161 tgtaaagcgt tggggtttgg actctgccta aggaaaagct tcctggtatg cctttttgct
     8221 gcaagagtaa actatacagt gggctaccgt tcatcccaat taaccaatcg gcgatctgac
     8281 gtgcttgtgc ttcttcaaat tttggatagg tctcttttgc gtctcgtaac tgctggaatc
     8341 cctgataaat ggcttctttt tctaaggagt tgatccaaag tcttttaaag gtttttcctt
     8401 gatcggcgcc tacttgttga atgatcgtcc aagcgatcag ttccccttca cgatcgctat
     8461 ctgtcgcaat aataatggtg tcggccgatt gaagttgctg tttcaccacc ttgaattgct
     8521 ttttcttatc tttaggaaca tgatagtgat aatgtgtagg gaaaataggc aaatgttcta
     8581 atgaccattg tttccaattt tcatcgtaca tatcgggcga atctaattcg actaaatgac
     8641 caaaaccata cgtgatcaca gtttcaccag gaaacaatcg atcttggatt tcaaaatacc
     8701 cgtcttttcg agtggcttta gagaagctat cggcataagc tttcgcttgt gacggctttt
     8761 ctgctaaaat aacggttttc atcatgacga tttcactccc tttcttgttg tctgccttgt
     8821 tgaaacaaca tggcacgttt ttgctttctg atttcttgtt gctggatctc atgcttcaat
     8881 tgatcgttcc agtccttttt tacttcaggt ataaattcat gttcatgatt tttatagcct
     8941 ttgtagtatt gttctgcttt ataagagaaa agaatctgcg cattaatatc ccctttttct
     9001 tgataaaaac gatcaaaatc gtacgtacca tccacgcgtt cacaaacttt taattctttt
     9061 gcgacttctc tacaaatatc tttcaaatta atggcttcta ttgaatcgtt aacagaaagc
     9121 tgctggccaa aaaacgcatt tactttgtga gcggaaacca gttggttcgt taattgcaga
     9181 ttgttttctg tcttgtgtat ggccataata gcttctggtg tgaccttttc ttcttttgcg
     9241 acttcttcat aaatgatttt gtattctttt ggcacttgcc aatcattagc gattcctcgt
     9301 tcacaacgta ctttctgatt cgtaaatgga tcgactgcgc ccattaattg ttctttttcg
     9361 tagaaaatat gtcctgcacg gtcattatcc acacaaatct cgatggattg aggaaaggct
     9421 tgtttctttc tcaattcaga tactgcctca ccaaaataat gactgatcac atggtgtttt
     9481 aacccttcca tagagactaa ccacgtatcg tttaactgat cacgattcag tgcagcatag
     9541 ctaagtaaat caatactact ctcaaaaaat tttaactgct tagggtcacc gatctttagg
     9601 ttaaagccat gattcgctgt cgaattttta tctatatgct tatatgtgcc tctctcacca
     9661 aaacgttcat aatcaatgaa cgttccttga taactcgccc ctactgtctc ttttgtctgt
     9721 ggatctttcc ataaaaaggc gaccgcatga tctaaacgat cgtctcgaac taagaaattt
     9781 tgccgttcat attttggctt tagttc
//
LOCUS       DAFKHN010000090         9525 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFKHN010000090 DAFKHN010000000
VERSION     DAFKHN010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.090"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            204..683
                     /locus_tag="LY912_002399"
     CDS             204..683
                     /locus_tag="LY912_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956050.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            716..2944
                     /locus_tag="LY912_002400"
     CDS             716..2944
                     /locus_tag="LY912_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBM6956051.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3073..4716
                     /locus_tag="LY912_002401"
     CDS             3073..4716
                     /locus_tag="LY912_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBM6956052.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4789..5334)
                     /locus_tag="LY912_002402"
     CDS             complement(4789..5334)
                     /locus_tag="LY912_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBM6956053.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5357..5842)
                     /locus_tag="LY912_002403"
     CDS             complement(5357..5842)
                     /locus_tag="LY912_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBM6956054.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5832..6644)
                     /locus_tag="LY912_002404"
     CDS             complement(5832..6644)
                     /locus_tag="LY912_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBM6956055.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6783..8315)
                     /locus_tag="LY912_002405"
     CDS             complement(6783..8315)
                     /locus_tag="LY912_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBM6956056.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIISLSPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8424..9455)
                     /locus_tag="LY912_002406"
     CDS             complement(8424..9455)
                     /locus_tag="LY912_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBM6956057.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWENMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3181 a         1788 c         1842 g         2714 t
ORIGIN      
        1 aatattccaa catcatcttg gactttctac atgttactaa tgagcgtgta aaagaacgag
       61 atggtgtttt tatttctatc aatgaagctc tttttctttg caatcctcac ttcaatcctc
      121 tataatgtcg catatagttt agtaaatgag taaactacta atttacttat ttactaaaaa
      181 taaaaggatg aggagttaaa ataatggaaa taccaacaaa tttaaaacat aaaccagtaa
      241 tcgttgtaga agactatgat aaagttgatg gaagaaatgc attaaatatg gatgcaaaag
      301 ggctttcact gggccttgct cagtggaatg atcgtggaaa agtcgatatc tcaggcaagg
      361 tatggcgaca tactggagaa aaatggtcac gacagtcgga agaattacca atcacacgta
      421 ttttagattt agcgatctta gctgcgcaag gaagtttata cttccaagat gcttatcgtt
      481 atgaaaaatt ttatgatcca gaaaatccag tcgtagacat cattggatta caagggaacc
      541 gaatgacggt agaagtagat accaaaaatc caaagatcga tgaagacatc attttgtatt
      601 acgatacact acaaaaagac ggagaactga ttggggaacg attccgtatt ttaaaacgtc
      661 ttttagatga gctaggatat taatagacag agatgatcaa aaggggaaga gaagcatgga
      721 gaatttctca ctaacagaaa accgaacctt ttcacggcta gaaaagcaaa tgatctggaa
      781 gaaaccgaaa agccatcgga caagtgcaga agaatggcgg atcgcctccg aaatcaaagg
      841 gaattggcaa gatcctgaaa tgaaaatcag taacgtactt ttggaaggag atgccgggtc
      901 ggggaagaca caattagcca aagcactatc tgctgatctg caacttccct atacaaaagt
      961 gacctgtttt gcagatatgg acaaatcaga tgttttcgga gccttattac ctgtagtaga
     1021 ttctaataag gaacaagacc aagaattact agaagctatt taccaaacag atacacttga
     1081 agctgtactg acactgatcc agaaccatta cggcattgat cctttttctg ctaaagaaaa
     1141 attagcagag ctagttcaaa ggatcgaagc tgattatcca gatgcaatcc attacagcta
     1201 ttacccttct gaaatcgttc gagcgattga aaaaggctat ttattagaga ttcaagagcc
     1261 gactgtcatc cgagatgcct ctgttcttgt ggcacttaac tcagcgctcg aaccaaatgg
     1321 gatgttgaat ttaccgacag gaatcattcg tcgccatcca gattgcgtca ttgtgatcac
     1381 tacaaatcga aattaccaag gaaatcgccc attaaatgaa tctttaagag atcggatgca
     1441 acatgcggaa aaaatggatc ttcctgcctt agaagtcatg gcagaacgtg cgatggcgaa
     1501 aactatgatc caaaaacaag aacttctctt aaagatggca gagattatcc gtttgttgga
     1561 tgaaactgca aaagctaacg ccatcaaagg tgtagcagga atgcgttctt atttttattg
     1621 ggcaaatacc tataagcaag gacaagattt actccagtcg atttatccaa aagttttgta
     1681 taaattatcc actgattcag atgaattggc aattcttgaa caagctttgt ctgacagtgg
     1741 attgctactg gaacttcagg acatattgag aaaagaaaaa tggggtcatc ctcaatctga
     1801 gcatacaaaa gaaagaacca ttagcgccga agaagcaaat gaacgaaaca tcactgaaaa
     1861 tgctgaagaa attctgcgct tagatgaaaa gaaatcgttg tctgctgaag aaccaaatga
     1921 gggagaagag aaacaagaag aaacaataga aaaaaacgag attcctcctc aaatgcaaaa
     1981 agaacgcagt agcgatatcg aaggaaaaaa tcaaaaagaa caacaaacag gagatgattc
     2041 tcaagaaatg tctgcttctg acatggaagc acatgataag gaaatcaaga agcaactgaa
     2101 taaagaagcg cgacaaatca tgaaggaaac gattcatgaa aaagaaggtc tcatcgttca
     2161 ccgaccagct ttccaaggaa aaacgccgga agcacgtgag ctacacatgc aagtaatgcc
     2221 aatagtagaa tcacttagcc ggcaaatttt agagttactg gataatgaac aaacagagac
     2281 gtaccaaaaa ggaaaatacg aaggtcagcg gttcaatgca agcaaagtag catatggtga
     2341 tttgagaaat tttgacaaaa agaacccgcc acatgagcaa ccttctttag cggtagctgt
     2401 acggatcgat gaatctgggt caatgatacg ggatgatcgg atcgaagcgg caaaaaaagc
     2461 agcgattgcc attgccgaat tttctaagaa agtcgatatc ccattgttga tttacggaga
     2521 tacagcagac cgttcgtcaa gagaaaagac ttctttgttt tcttataaag aatttgaaga
     2581 cggatttcaa tggttaaatg aaaaattagt cactatgaaa ccaaggcaaa acaatcgtga
     2641 tggtgctgca cttcgtttag cagcagaaaa attaaacaga caatccgcaa caaccaaact
     2701 gttgcttaat attagtgacg gtcagccaaa agcgttgccg gattatacag gcaaaaaagc
     2761 aaaagaagat atccagtctg ttttgaaaga atatgaacgt caaggaatcc tatttgtctc
     2821 cgcagctatt ggccaagaca aagaagaaat caagtcgatc tacggtgaaa gtcgttttgt
     2881 agatattact gacttgaatg aatttcccaa gcaaatgatt caactgattg cccgctatct
     2941 atgataaaat aaagctcagc gaacgcactt agcagattcg ttgagctttt cgtttctagt
     3001 taccggtaac aaggatactt ctaaaataga atcggttata atcaagaggg accgttaaag
     3061 gagtgaaacg atatgataca agaacaaaaa tggtggaaag aagcagtagg ctatcaaatc
     3121 tatcctgcta gtttcaaaga tagcaatggc gatggtcaag gagacatcaa tgggatccgt
     3181 gaaaaactta attatttgaa agatcttggt atcggcttta tctggatcaa tccgatctat
     3241 caatctccat ttgtcgataa tggttatgac gtaagtgact atcaagatat agaagagaga
     3301 ttcggaacga tggaagattt tgatttattg ctaaaagaag cacatgaatt agggatcaaa
     3361 gtgattatgg atcttgtcat caaccatagt tcggatcagc atcaatggtt tgaagaatcg
     3421 aaaaaatcta aagaaagccc gtatcgcgat tattacattt gggtcgacgg ggtagatggc
     3481 aaagaaccga ataattggac atcgattttc ggcggttctg cttgggagta ttctcatgaa
     3541 actggacagt attatctgca tgtttttgca aaagaacaac cagacttaaa ttgggaaagc
     3601 gagaaattga aagaagaact attcaatatg atccgatggt ggttggataa agggatagat
     3661 ggatttcgtt tagatgcgat ttctcatgta aaaaaagatg aatattcagt aaaagccaca
     3721 gagaaccctt tctcaccctt tcaaaatgtc tcaggaatcg aagaacattt gaccgatttg
     3781 aaacatgttt ttgaagagta cgatatcatg actgtcggag aagcaagtgg tgtcactgca
     3841 gaagaaggac cacaatgggt agggaaagac ggttatttcg atatgatatt cgaatttgat
     3901 catatccata tctggcagca agaaaaagaa gggcaattag atgtccttaa attgaaacat
     3961 gcattaagcg cttggcaaac ttcattggat ggtatcggat ggaacgcttt atatatggaa
     4021 aaccatgatg ttcctcgtgc cgtttcagtg tttggagata ctcgtcccga tttttgggct
     4081 atgtctgcaa aagcaatcgc tatgatgtat ttctttttgc aaggtacgcc atttatttat
     4141 caaggacagg aaatcggaat gacgaatatg ccctttgaat cgatcgatca agttgatgca
     4201 gtagattcga aaagacttta taaaaggctg cttgcggaag gtaagacaag agaagaagca
     4261 ttggatatca ttcgtgaaac aacgagagac aacagcagga cacccatgca atggacttcg
     4321 gaacaatatg ctggtttttc tacacatgaa ccttggctga tcactaatcc aaataccaaa
     4381 acgatcaatg tagaacaaca agaatatgaa ccagagtcgg tcctgcaatt ctataagaac
     4441 atgatccgca ttagacaaac caataaaggt ctgatatacg gttcttataa agaatatctt
     4501 catgaacatc cacaacttta tgtctatgaa agatatttag aagatgaaca atatcttatt
     4561 atggtaaact taacagaatc acttgctgac tatgaacttc caaaagaagc agatcagtcc
     4621 tggacattac tcttgtcaaa ttcctctagc ggagaatttg aagctaaagg catactagca
     4681 ccttatgaag ctcggttata taaaacaaac aagtaaaact tcctcgttaa agttcattag
     4741 ttggactttg cgaggaagtt tttcagattg ctctgtcaat tactcatttc aataattcgc
     4801 tctaggacca ccgatatatt taggacgaga gcgaagggct gtcacgtgag cttgtccaag
     4861 ggttttcaaa cgaggtctga caggtacttg gacatgcttg atatgcatac cgattgatgt
     4921 gtcaccgata tcgataccgg cttgtccaac tacgtgttcc acttcgacag gatcattgaa
     4981 ctggtcaaaa gcagcaacag aacaagcacc tccagcatgt agtgcaggaa caacagagac
     5041 aatttcgaaa ttttttgctt ctgccactgt tcgttctact actaatgctc ggttcaaatg
     5101 ttcacaacct tggacagcta gcgcaatttc tttaggatcc aacaactctt ttaacgtacg
     5161 gatgatccat tgaccaactt ccgcactgga attttttcca atatgtcctc caacgacttc
     5221 gcttgtgctg catcctaaaa caaaaagatc accttttttc aagtgtgcct cagccaatat
     5281 gtcattaact atttcagtca attggtcttt taattctttt tctgacaact tcattttcta
     5341 aaaccttctt tttcaattaa tattgcttcc gtgcttgaat acgttgaaga cttgcagtta
     5401 taggaaaggc aagtcccatt ccaatcagat tttggaagat gtttcctggt atagaagcca
     5461 ctccagccgg ccaatcatat aaaatccaac cggcgatacc atagccgatg atcataacta
     5521 agcttcctaa taaaagccct aatccccaca tacgagtaga agatttgctg aaagaaccag
     5581 caacatatcc ttgtaacccg tggatcacta atgaaaaaac tgcccactgc ggatatcctg
     5641 aaatcaaatc gatcaataga ccactggaag caccaacaac taatccaccc gttggaccat
     5701 aaagaaaagc agcggtatag atcccggcct cgcataatgt cacaaatcca ttcgtagccg
     5761 gtacagggat caaaattgtt aatgaaaggg caactgtcaa cgcaatcagc atagcataga
     5821 tcgttaattg cttagttttc atttctcatt cctccttttt gaataccgcc agaccagaca
     5881 cttccggtat gatcgttcat cagcacgcca ttagaaatac aatgggcaac aaatttttta
     5941 ctttctgcta ctgctttggt aaaatctgcc cctaacacaa gattcgctgt tattgcagaa
     6001 gaaaaggcac aaccggcccc gtttactgtt gtagtgtcga tttttttatg agaaaatacc
     6061 tcataatgat caattgaata gagaagatcc acagcttcat ctccagccat ccttgtgccg
     6121 cctttgatca caatgttttt tgttcctgaa gcagtgagtt ctttagcgag atggatcatt
     6181 tctgttaacg aagagggaag agcttgacca gaaagtaaag cagcttctgc caaattaggc
     6241 gtaatcatcg taacaagtgg aaaaagttct tcgatgagct gcgaaatata caattgattg
     6301 atcacagctt cagtttcttt gaatgccaaa acagggtcta aaatgattgg gatattttgt
     6361 tttgttttta tgaagtctcg aacaaccatg attgcttcac ttgaattcaa taacccaatt
     6421 ttgataccat ctaatgaagt cattttatca atcgaaacta actgtcgttt aagcaattcc
     6481 aaagatatag attccagcat aaatcgctca ttaatatcta gtgcccctat agaagtcaag
     6541 gcgcttagtc cgaatagacc aaaattctca aaagttttta aatctgtttg gattcctcca
     6601 ccagcaaatg gatcagaacc gccaattgtc aagattcttt tcataacatt ttcctccatg
     6661 aataagagta taacgaaatt ttcaaaaaag aaaaacagcc aattggcata tttttatctc
     6721 atccaattta aaaaaacaaa aagaaaagaa agaccaaaat ggatctttct ttccttaaat
     6781 agttaggact tttgtgattt taattctttc tcgatttgaa gccgttgcac tttcattgta
     6841 gctgttcgcg ggattgcatc aaaatcacgg atgataggga cgttcaagcg aggaagttca
     6901 tggacttgct cccaccatcg attccaatcc atttctttat caggagataa agaaataatc
     6961 ggttgtggag aatgattttt atcccttaca atcactactt ctgccaaaaa atctaacgaa
     7021 tctaataaaa agtcttcaat agctaatgta ctattgatcg tttcgatcaa atccacttgc
     7081 cgatctttca aaaataggtg gccatgctta tccataaaac cgtaatctcc gctatcccac
     7141 caatcgccat aaacattttc ctggaaccgt gcatcttcct tgtaataagt caaagcccgt
     7201 cctttagaca gtaattgtat atgaccatct gtgttttcag gtaggacatt cccaactgaa
     7261 tctgtaatcc gagcgcttgt catgtcttcc agtccaacgc ccatatctct tgcatcactt
     7321 gttttcaaac tctctagtgt atgagcctta agaatcattg gtccgcattc actttggcca
     7381 tatacttgaa gaaataccgc atcctgtgcc atcgacgttc gcaaaaatgt cttcattgtc
     7441 tggttgttta tagcatcaaa agtggagtga tagtatcgga tacccgaaaa agcttctgga
     7501 tgctccttag cagtaaaacg ccactgaaca aagttattcg gatgggtctc tagtgcaatt
     7561 ggccggtgag cttccaacat atgaacaact tttgaacttt gtgcgtttgc taaaggcatc
     7621 ataggaaatc ccatggacat caaagaagag ataccaatat tgaatctgga atgcactgga
     7681 gagatgtgaa aagcgattaa tttcttttcc gaaatttttg tgaaaactgt tttttgccat
     7741 ttcgtccgcc atcccataga atgagcagaa tgacaaataa gtttagggat accagttgta
     7801 ccagaagtat gggtcatata agaaatttca tttttgtcta aaaatgattg agaaacagac
     7861 aaagcaggtt gttccattaa ataaagaata ggaatctgtt ttgattttgt tccatttgaa
     7921 atttctctca ctcgcttttt tgtctcatca tcaaataaaa tgaaagggtc ttctaaacga
     7981 tcgataaata cttccattgt tgttgttggt agatgataag aagtcatgac aggcactgca
     8041 ccaaggtaag acacagaaac agctagaagg tatgtgtcaa aagcggaact cttataaata
     8101 ataactttgt ctccggattt cactccaaga tgagccaatt gataagcccg tttcaacaca
     8161 ctttcgcagc attttttgta agttgtttca agtcctaatt ctgggaaagc tgaaagtggc
     8221 tcatcaaaga taatcggggt ctcggaaaag ttagctgcag cttcttgaaa attcgtaaat
     8281 aagttcaaag gggaatacgt tatggtctcc atcattcaca ctccattatc ttttgttaag
     8341 taatatacaa attcaagata atcgtaacat aatcctttat ataataacat agtttattgt
     8401 gaaaaaaaga tcatacattt gttttatatg gaagaaaccc gaacgaatgc cgctaattcg
     8461 tgataagaaa aatcaaccat attttcccag atatcttgaa aagaatggga tgagaggtat
     8521 cgattaccac ataaataatt taccgcgtca gcatcatcta aatatagttc tgcataataa
     8581 cgatatgttt ttctgcatag ttctggcgat acgtttttat atactgtaat tttgctcaaa
     8641 atttggcgaa tagtccgagg agaaatttgc tgatcatgtg aggaacgaaa aacaaaagaa
     8701 ttttcgtccg tattttgtgc tgttaactta aaatagttct ccagaaatgg catcgcttct
     8761 tttggtattg gtactttatt cagtctgttt tcttttctat tcagattaag aatctgcttg
     8821 gtcaaagata catctttacg tttaagttct actacttcat ggatctttaa tccgcaatac
     8881 agaagaatgg cagtaattgc aaggttcctc ggtctattct tttcttcaaa gctagcttct
     8941 ctgcttgttt gaaagccttc aatcgggata aacaaatgct caaaatcttt gaaaagttct
     9001 gcatcgatat atcgcggagc tgctttggtt gtttccggta aacttgtacc caaaagagaa
     9061 atctcttctt caatcagtcc tttttgatac aaaaatcgta aaaaatgatt taatgaatat
     9121 tgcttccttg aaatcccgta atagctattt tcaaacaatt gctccgtttc ttggttcgct
     9181 gtagtttgga acgaacgagt atgtcgatag attttagcta agaaattctg ataatcttgt
     9241 ttttctaaat ggataatcag ctgatcatcc acttcttcag aaaatacttt tctcaaataa
     9301 tcagtaaaca gatgaaaatc ttttgcgtat tcatagcgac tgcctaatga aagggaagaa
     9361 cgattttctt ctaaaaactg ttgaaagacg gaagggagca agtgtgtacg ttgctttaac
     9421 ttttcttgca gttgttttct agttttgctg tccattacaa attccctcca atagtgttca
     9481 ttttctatat tttaccgcat ttcatcaaat gaagatagac agttt
//
LOCUS       DAFKHN010000091         9458 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFKHN010000091 DAFKHN010000000
VERSION     DAFKHN010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.091"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(198..1706)
                     /locus_tag="LY912_002407"
     CDS             complement(198..1706)
                     /locus_tag="LY912_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBM6956058.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            1865..2056
                     /locus_tag="LY912_002408"
     CDS             1865..2056
                     /locus_tag="LY912_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956059.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            2259..3176
                     /locus_tag="LY912_002409"
     CDS             2259..3176
                     /locus_tag="LY912_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBM6956060.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            3169..4242
                     /locus_tag="LY912_002410"
     CDS             3169..4242
                     /locus_tag="LY912_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956061.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            4390..4908
                     /locus_tag="LY912_002411"
     CDS             4390..4908
                     /locus_tag="LY912_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956062.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            4889..5281
                     /locus_tag="LY912_002412"
     CDS             4889..5281
                     /locus_tag="LY912_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBM6956063.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            5357..6292
                     /locus_tag="LY912_002413"
     CDS             5357..6292
                     /locus_tag="LY912_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBM6956064.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            6425..7204
                     /locus_tag="LY912_002414"
     CDS             6425..7204
                     /locus_tag="LY912_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBM6956065.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            7197..7514
                     /locus_tag="LY912_002415"
     CDS             7197..7514
                     /locus_tag="LY912_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBM6956066.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            7758..9368
                     /locus_tag="LY912_002416"
     CDS             7758..9368
                     /locus_tag="LY912_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBM6956067.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
BASE COUNT         2957 a         1658 c         1901 g         2942 t
ORIGIN      
        1 gttttgcaaa taaaatacta atctttagtg aaattttcat tactttttta gagtgaaacg
       61 cattcatttt ccattagaaa ataaagcgaa caaaataaaa ggtttaaaaa gtgtaacgtc
      121 ttagtaaagt ctataaaaaa acgaaactat cgattaagct aatagtttcg ttttcaacat
      181 ttataagtaa actttttcta ttggtaatat agattttcgg aagggtagac aggtgcgcag
      241 gtaatatcga ttcctagttt tttcaatgtt tgttcatcat ttttattgac catcacagta
      301 gagtgggctt gtgctccctc aagttcagct agtttatcat aagcaacttg agcgattgga
      361 ttcgttactg cactgattga taaagcgatc aagacttcat tgatgcttag tgcatccaaa
      421 gaggaatgaa gtgtctttga tttcaatcct tgtattgttt caagaactaa tggtgacaat
      481 aaaggaatgt catctgcgat atgggctaaa tgttttactg catttaagat aactgccgct
      541 gacgcatcca tcaatgaact tgtacgcccg gtaatgatga cttcatctgg taattcgatt
      601 gcaatcacag cagaaggatc ttttgtagga ctttgcgctt gaatcttatc tgcatagtca
      661 tgggcaggga ctaccacgtt tcggtcttca ggacgtaaac cgacttcttc cataatcagt
      721 ttgattcgat taactgcttc ttcgtcgatc aatccttttt tgaagtcgca ttctgtttgg
      781 aaataacgac ggatgatttc ttgtttagag gcttcttgga caacggtatc atccacgatc
      841 ccaaatccta cacgattcac acccatgtca gtaggagatt gataaacaga ttctttacca
      901 gtaatttttt caataatacg tttgattaca ggaaatgtct caacatcccg attatagttc
      961 acagctactt tattgtaggc atcaaagtgg aaggaatcga tcatattgac atcttttaga
     1021 tcgactgtgg ctgcttcata agcaatgttc agcggatgtt tcaacggaac attccatact
     1081 gggaaagttt cgaacttgga gtaaccagct gcatgtcctt tttggctttc atgatacagt
     1141 tggttcaagg aagtagcgag ctttccactt cctgggccag gagctgtcac tacaacgatt
     1201 ggtttagttg tttcaatata ctcatttttt ccaaaaccat cttctgagac gattttttct
     1261 acgttgactg gatagtcttc gatttctgag tgtttataga ccttgatgtt tcgtctttct
     1321 agtttattga taaagacttt cgtggcaggc tgtccactat agcgagtgat aacgacactg
     1381 ttgattaata agccataacc acgtaattca tcgattaacc gcaagatatc catatcataa
     1441 gtaatcccat aatcaccacg gatcttatta cgttcaatat ctccagcata gacgcaaatc
     1501 agtatttcag cttgatcttt caatttttgc agcaatttga ttttcgcatc ttcttcaaat
     1561 cctggaagta cacgtttcgc atgcttgtcg tcaactagct tcccaccaaa ttctaaatat
     1621 aatttgtcat agtggttcac tcgttccaaa atatacgctg actgctcttc aatatatttt
     1681 tctgaatcaa aaccaatttt tttcactagg ttccctcctt aagtactaaa gcattttttc
     1741 atttttttga ggattcgtca actggaagag cgaaattcct caaaaaaaca aagaaaatgg
     1801 tttaaaccaa cttgtctaga tagttattca ttggtatgat agtttttgat aaggaaggtg
     1861 ctacatgaaa aaaagacaga aaaagaaaaa cgcatataaa cactatatcc gttcgatttt
     1921 taccggttat gaaagaatgc ttgaagatcc cgaattggaa caattgacgt ttacttatct
     1981 aaacgaagaa acgcagctaa ctcgtgatga gcatcagcgc attcatttca caacaagaga
     2041 tctgcctagt aaataaaaaa taagataaag gtcatcggat tcgattctgt cctatcagat
     2101 ggaaagacta gttgatcgaa aaaaaggctg taccaaattt tggtgcagcc tgttttatgg
     2161 agcattgccc gctctttttt ataacaattt tttacagaaa atggtactat tgaagtatta
     2221 ataagtgaaa aacagatgag taagaggagg caagtagtat gaaagagcca gatacaaatg
     2281 caaattatga gccagacgaa ctagaggaga cgaatgcgga tcaggataca ggacaagaat
     2341 cgtcttcttt ttacgatatc aaagaaaaag caagcatgaa tctttcccaa ttattagaag
     2401 acttacaggc ttttgaaaaa gctgtccgcg aagaagatat ccctgagatc taccgtttat
     2461 acaatggccg attgaatgaa gaattaaaaa gaagctcaaa tgaaaatcac gagatcgatc
     2521 aattgctgat gcgtaagatc catgatcgtt ttttacagga atttcctttt atggaacaag
     2581 tagaaaacat ctcgccaacg atgagctatt acaaaatcgg cacttattac catgatcggc
     2641 ccacggtcgg tattgatgca agtctgccag aaatttttgt tttgcctaag atcgatgaag
     2701 agtgggagaa atattcccaa ccggagtcaa cggactatga caaaaaaatc aatgagctag
     2761 acgcaaaggt gatcactgct cagacagaaa ttgaacgttt agatgaacaa ataaaagaaa
     2821 tcaatcgaca aatgactgat ttgaacgaca ataaaggatt cttgaatcgt aaaaaaatcg
     2881 aggaagaaat tcaagaatta gagaagaaga agcaagtact atctaatgaa aaattaggct
     2941 ggcttcctta tattgagacg cctgaaacaa tccagcagca aaaagaagca ttgaagcaag
     3001 aagcaagagc agaccagctt cgtgcagcca tcgtagaaaa agaacaaagg caaatcagac
     3061 gctatttcgg tagcaaagag ggattcggtc aagcaatcca tgaattcttg atgaattatc
     3121 ttggcaatga gaatcctaat aatcaatcta atgaaggagg ttccgagtat gaatgaacac
     3181 gatgaagcag aatggacaaa aaatgaagaa caaacagaag atcatgaaga aacgaacact
     3241 tcattggaag aacaaacaag taatcctctg gatgacacag aagaaatccc tatgctagag
     3301 gaaacaaaaa tacacgaaaa agaaaaagta actccgacga atacgaatac tgcagaaaac
     3361 acccatgctt acgaaataac tgaaaatccc gggtatttag aaggaaaaga gcaagatcat
     3421 caagatatcg tcagtttgat tgaaacagcg gaagcagaat tagcggattt acgtatgaga
     3481 aaagatttga tcgaatcaga ttttccacaa ttattagaat catatgatcg ttttatattg
     3541 aatgaagaac caatctccac gatcggaaag acaagcctga tcgaatactt cacgtatgaa
     3601 ttactgaaac cgttgaatga tattggtctg gaacggtcaa attcagctta tgacacatgg
     3661 aaaacaagac atttttcgat caattatacg ttgaatggac aaaacgaatt agtcttttcc
     3721 tttgtattac cgaccatcga tcaacgatac caagtggaat cgatgagtct cctaaacgta
     3781 tcaccagaga caatggaaat caatgtccaa gatgaccggg tgctttcttt gatccgacac
     3841 tggtcagtgg atcgagtatt ctctgcaggg cagatcacga tattcaatca caaattgaat
     3901 caattattag cccatgcaag aacacttggt tttaccgtta atcagacatt actagacaat
     3961 acgaagccac ttcgtttgaa tcttcagagc gaatttgaat tgacgaatga agtattggat
     4021 gatattttta tcgtggcaat gaaaaatcca tcctacgata tggaaaagat caacgaaact
     4081 acttatcaag tacgattaga taaaggacag tctttaacga taacaacaaa cgaaaaagat
     4141 caaacagtct tgtcgatctc atctggagac tacccacgat ctgtcattga tttctttatc
     4201 aattacgaat tcttggtccc attaatggtg agaaagtcct gattggataa gttggattac
     4261 cagatgtcat tcagataatt ctgttccaaa ggacttgcgg cagttatcca gaataattgt
     4321 cacaagtctt ttctgtatgt actaaatgga cgtgaataac ttgctgatga aggagggatt
     4381 tcattaggaa tgtccacaaa taaaatagca cagcttagct tattgtctgc tgcttgtgta
     4441 gcaggtagga tcgcttttca atttattccg aatttccagc caatgactgc tattttttta
     4501 tttatagtac tttacttaag cttaaaagat gcgttaattg tcatgagtct ttctattgcg
     4561 atcagcagtt tttattttgg tgttggacca tgggtcatcg gccaatggat cagctatact
     4621 gttgttctga gtttgttttc aatcgtctgc ttgagaaaaa cagtgcaaag gaatctatgg
     4681 ttaaagggag tctgtttttt tctggcgggc atggtttacg gaataggtat gaccgttttt
     4741 gatacgctgt tatatcgttt gcctcaacct tggatctatt accttcaagg ggtgtcgttt
     4801 gatttgatgc acagtatagg caatgttgtg ttctttcttg tttttctgcc agtcgtcaaa
     4861 cgtttttaca atcattcagg aggaaaaaat gaaaaaaata atttatagtt tgcttgcaat
     4921 gagtgtcagt atactcattt tgacaagttg cagtacaacc tatacacaat cggcttccaa
     4981 ccaaaaggag gaagtaaaaa catcgcaaaa agcaacaatc acgttacaag aaaatggtca
     5041 aaacttttcg gaaaaagaag tgttcttcaa aaaaggcgat gatttactga gtattttgaa
     5101 acgaaatttt gaagtcaaag aagataacgg cttcatcact tcgcttgaag ggcactcaca
     5161 ggatgagaaa aatcaactct attggatgtt tactgtggac gggaaaagtg ctactactgg
     5221 tgccaaagag atcaaattga atgatggaca atcggtcatt ttcaatttgt ctaaactata
     5281 agtttcataa aaaactgtta aagggcgaat attgccataa ttcagtgagt tcagttgatg
     5341 aaagaaggaa aataacatgg aaaattttaa aaaaagcgga atgttttccg taattgctgc
     5401 tctaggggct aatattctag ttgctatcag caaatttgtc ggctatgcaa tcagtggcag
     5461 tgccgccatg ctaaacgaaa gcatccacag tatcgttgat tgcagcaatc agattttgct
     5521 gttattcggt gataaacaag ccaataaagg acagagcgag ttgcatcaat ttggtgaagg
     5581 acgagcaaaa tactttttca gtacaatcgt cgcaatgatg cttttcttcg gcggtggggc
     5641 acttggggtg atggaagctt ttgaaaagtt gacgcatcca tcccatgaag tgggtaatcc
     5701 gatcattgtt atagcaatac tgttatttgg tttggtaatc gaaggaagtt cgttacgcgt
     5761 ggcaatgaaa gaaatcaaag aattgaatac tgaaaaactt tccacgatgc gctttttgcg
     5821 cgaaagtcga cacagtgaaa tactgattat ttttacggaa gacttgtgtg ctgtaatcgg
     5881 tttggtcttg gctttagcag gaacaatatt gacttatgca accgggattg ctgcatttga
     5941 tgcgatcagc ggattgctga tcggtttctt gctgatggga gccgccattt tcctagcaaa
     6001 agaattttat agtctgatca tcggtgaaag cgtgacagca agcgatttat caaaaatcaa
     6061 gttagctttt gaacgtcctg agatcagtcg gctgatcgat ataaaaacag ttcatttaag
     6121 tccaacggag attttagttg cagcaaaagc agatatcgtt ggtaacaaag agaatgaagc
     6181 ttactcggtc atcaatgata ttgaaaaaaa tatgcgtcag tctcttcctg acaagaagat
     6241 gtatatatac attgaaacag ataaatatga cccaaattat tctcgtaaat aaaacgttta
     6301 ttcatgaatt gaagcaaaaa tgagaaaaat ataatcttgt ttttaaataa aacggctaca
     6361 atttagcgaa tttatgttac aatgagtccg ctgtttattt gttgtaatta aaggagatat
     6421 tttaatgaac aaaaagaaaa gtgcgccatg gcttcaagct ttgcatgcag tgatgccact
     6481 ttgtataagc tatataccag taggattagc ttgcggagta ttgttgcaaa aagttggatt
     6541 tgatcctctc ttatcaggac tgttatcgat tctggtcttt tccggtggcg cgcagttttt
     6601 agttgcatct atgcttacga cgcaagcatc atttgcaacg acattattga tggttttctt
     6661 tttagaatta cgctatacat tattaggagc aagtcttgcc ggttttatga aaaaagaaaa
     6721 gcggacgttt ttggctgtct tttctcaatc actgaatgat gaaaactatg cggtgaacta
     6781 cttaaagttt tcaactgacc cttcctggaa taaaagaaag gctttatatg tcaattggtt
     6841 ctcaatgact gcatgggccg gtagcaatat gatcggtaat tttttcggct cggtgattcg
     6901 agtagatgct gaccttgtcc attttgcttt gacggccatg ttcattttca tgtttatcat
     6961 gcagatgaaa agcgcactac tgatctttac aggtttattc tcaggcgtat taggggtcgt
     7021 attcatggta ttattccaaa atactttcgg attgattgca gcaacagtca ttgcttcatt
     7081 tgccggattt atgctggaga aggcattcaa aaaagaaaaa gctaagaaac taagagaccg
     7141 cggtaaagat gtcaatgagc cgctcttcaa cttcccggaa caggaggcca atcaccatga
     7201 ctaaactata tttgctactt ttagttgctt gtctgttcat cgtggcatat atcccgcgct
     7261 tgttcccgat gctttatttt actcatcgaa aagtgccatc ctggttcagt gactggatga
     7321 aatatgtacc ggtggcatta tttgcggcgt tagcttttaa agatgttttc attactcatg
     7381 aacatctgga tattgcttgg aatatcaaaa tagctgcaat gattctagta gcaggcgtgg
     7441 cttacaaaac acgttcgatg gcgttgtcag ttttgacagg acttgcgtct gtctttttgc
     7501 tgtctatgct ttaaactgtt ttattttatt aaaaacagag attgcgacat aagttgttca
     7561 aactgatcta tccgaactgc atttgcaaca gtcaattctg gatgcaagtt tattcgtagg
     7621 gataaaaaag attagtgttg gcttatgatg caagctcttt tttattttag gaattagaga
     7681 gggatttgtc cttctatgat tttttgctat aatagggaag atgtttattt tatgaaagaa
     7741 tagttgaggg aatttaaatg aataaaaaat tgatgcaagg aacattttgg ctaacctttg
     7801 ctaatcttct atgtaaagtt ttaggggtag tctatttgat tccctggcta agtatgatgg
     7861 ggaacaatca agatggtatg cttgctacga cattgtataa tgttggctat cttccttatg
     7921 gattgttcct gatgcttggt acagtcggat ttccaaatgc gattgcaaaa aaagtagctg
     7981 tagccacaaa agaaggagat aacgctgctt gtcggctgat ttttagaagt acgatcaata
     8041 tcatgtttgt catcggtatc gcctctgctg cactgatgta tttatttgct cctttactag
     8101 ccggaatcag tccgattgct aacgttaata atgggatact agctatcaga agtttatgcc
     8161 catctttgat tgctatccca attcttagtg caatgagagg atatttccaa ggaaaaaatg
     8221 atctgcggcc ttatggaact tctttgatta tcgaacaggc tgtgcgagtg atcgttatct
     8281 tggctggtac ttattacttg cgcgtattga ctgacggaac catattagaa gctgtattga
     8341 tcagtacagt cgcttctttc ttcggtgggt tagctgcgat tatccatatg tatatcgtcg
     8401 gacgcagaaa agacttcttc gaacttaaag attttttgat ttccagccgt tatttcgaaa
     8461 gagaaaaccg atctgcctct gtctctatca ttcgggaaac actaccgttt atttttgtcg
     8521 gctcagtcat tactatcgtt caaatgatcg accaagtaac gatgaaacca ctgcttcact
     8581 ttttccgtcc agagatcgca gatcagcaac tggaattctt attcagccgt gcttctgtca
     8641 atccaaataa attgacattg atcctgatct ccatggtagg aacagtagct ataagcagct
     8701 tgccaatatt aagcacgatg aagaaaaaag atcggataca aatcgaaaaa acagtaggag
     8761 atagtttttc gattgcgtta ttgattcttc ttccttcatt gactggaatg tctttattag
     8821 ctggaccact atacacattg ttttttggct atgatcctga aagtgtcgga tatttccaaa
     8881 tggctttgct agcttctttg tttttctctt tattcacgat cctatctacg atgcttcaat
     8941 ctttgaatca ccatcgtttt gcgatccgat taactgtaga agcaattatc ctgaaagtca
     9001 tcttccaagt aatcggatta ggattagttg gcggatacgg gatgagctta tcaaatggct
     9061 tagcattcgg tattgtcttt gttcgcggct atcactttat gtgcaaagaa taccgaatag
     9121 cacctttagc aaagatcagc aattttttct taaaaacttt ccgctccacc ctgattatgc
     9181 ttgcagtatg ttttgccgtt ttctttttgc tgaatcagcg attgtcaatg gaatcaaaaa
     9241 gctatgcaat gatttattgt gtggctgtag gaagtattgg cggcttagta tttttatttt
     9301 ctcaattcgg aaaaaatggg tttcgaatgt tgaaaaatgt taaacatcat agcagaagca
     9361 aagaataggt taactaatcg ttttttgctg tcacttgaaa aacggcaact cgtatgatta
     9421 cgcttgtcgt ttttctattt tccaatttta gtttcata
//
LOCUS       DAFKHN010000092         9399 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFKHN010000092 DAFKHN010000000
VERSION     DAFKHN010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.092"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..389)
                     /locus_tag="LY912_002417"
     CDS             complement(<1..389)
                     /locus_tag="LY912_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956068.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFIT"
     gene            complement(686..3067)
                     /locus_tag="LY912_002418"
     CDS             complement(686..3067)
                     /locus_tag="LY912_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBM6956069.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(3057..3704)
                     /gene="recU"
                     /locus_tag="LY912_002419"
     CDS             complement(3057..3704)
                     /gene="recU"
                     /locus_tag="LY912_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBM6956070.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3768..4307
                     /locus_tag="LY912_002420"
     CDS             3768..4307
                     /locus_tag="LY912_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBM6956071.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4397..4816
                     /gene="gpsB"
                     /locus_tag="LY912_002421"
     CDS             4397..4816
                     /gene="gpsB"
                     /locus_tag="LY912_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBM6956072.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4838..5205
                     /gene="rnpB"
                     /locus_tag="LY912_002422"
     ncRNA           4838..5205
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LY912_002422"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5414..6580
                     /locus_tag="LY912_002423"
     CDS             5414..6580
                     /locus_tag="LY912_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBM6956073.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6626..8122
                     /locus_tag="LY912_002424"
     CDS             6626..8122
                     /locus_tag="LY912_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBM6956074.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            8203..8886
                     /locus_tag="LY912_002425"
     CDS             8203..8886
                     /locus_tag="LY912_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBM6956075.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         3028 a         1651 c         1952 g         2768 t
ORIGIN      
        1 gtaataaaaa tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg
       61 gatttgggcg gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa
      121 aaagtgagaa tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt
      181 aaaagtacag aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat
      241 aataaacaaa atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa
      301 aaaagatggt gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag
      361 ccttctttca aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg
      421 ggattattaa gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata
      481 aacaagtaaa tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta
      541 agctaaatgt tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac
      601 agcttggtac atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac
      661 gcttgtagac gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg
      721 gtgtatggtc atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag
      781 gagcagatga agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag
      841 acgctggctc gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc
      901 tttgactagt agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct
      961 ggacatagct ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat
     1021 attgatcttt gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt
     1081 ctgtatttgt cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta
     1141 cgtgtgacga ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa
     1201 tcgaataatt tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac
     1261 caagttttgc atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata
     1321 acccagcgat ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg
     1381 tgatcatata agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt
     1441 ctgttccgtc ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat
     1501 tggcgaaagc cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat
     1561 cttgttcttc cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc
     1621 caagattttt taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg
     1681 ctggaacatt acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat
     1741 tatcccagtt tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag
     1801 tttttccagt agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca
     1861 tcgtagaacc aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt
     1921 ctgcgatgtg acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg
     1981 tggaggcaac ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat
     2041 catatagttt cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt
     2101 agacattctt atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga
     2161 cgatcttagt attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat
     2221 taacagcttg atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa
     2281 cagtatctcg tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg
     2341 cttgaggcat cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac
     2401 caaagtacat ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat
     2461 ttacgtagta ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc
     2521 acgcttcttg ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa
     2581 gtttgatcaa ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag
     2641 agagggcaga accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat
     2701 cttctaccga cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt
     2761 cacgcttttc tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag
     2821 atacggtagc gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga
     2881 aaagtcctac acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct
     2941 tgataaataa tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct
     3001 tcttcacact ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat
     3061 ttgccattct tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc
     3121 aaataaggaa tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa
     3181 gataaaggta gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga
     3241 acactattca aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc
     3301 ccattttgtt cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag
     3361 ggaaaagatg ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag
     3421 acgccattat agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca
     3481 cttctcttag gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc
     3541 gccaacccgc gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc
     3601 ccccgattgc cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag
     3661 gcattcttat aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct
     3721 aggccacatt atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa
     3781 aagtaatcta tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc
     3841 ctaaaatcca agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag
     3901 ggctggaatg ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag
     3961 tagcggaatt gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg
     4021 attttggtaa taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag
     4081 cagattatgt cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc
     4141 acactcgttt tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc
     4201 ctggaaaaac gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg
     4261 aaattcggct gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt
     4321 tgatttatca acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa
     4381 aactagaggt gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga
     4441 attcaaaaca aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat
     4501 catcaaagat tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg
     4561 attgagtgca aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca
     4621 acaaacagag gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc
     4681 aaatcttgaa cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc
     4741 agcacaacct aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa
     4801 aacacgtcaa ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga
     4861 cttgatcagg ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc
     4921 ttagcgaaac cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct
     4981 tcggctatgc ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat
     5041 ccggtggaac gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt
     5101 gtctggaaga agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg
     5161 ttttttctcc ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag
     5221 ggaattaggt cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta
     5281 tttttcaata cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta
     5341 ttcggaattt gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat
     5401 aaggagattg tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg
     5461 gctagaagca ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa
     5521 cggacgtgca cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg
     5581 tacagcagat cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt
     5641 gtttgaaaac gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc
     5701 tgtagctgga aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac
     5761 aaaaaaagca atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact
     5821 gacggaaact ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt
     5881 aactctggat acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg
     5941 agcaccattg aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga
     6001 ccgtccattt tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat
     6061 aggccataat atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt
     6121 cagtcaagaa atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat
     6181 tgaattagat attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa
     6241 tgcagaagaa atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt
     6301 caaaacggat aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg
     6361 agaagaagaa actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa
     6421 aacatggagt aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa
     6481 agcaaccaaa aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg
     6541 gggaactcgt ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc
     6601 aattggatgt ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga
     6661 aatcaatctt ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc
     6721 tgaaaaagct agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc
     6781 aaaaaaaatc ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga
     6841 attgtcggaa gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca
     6901 tcgcgtaccg gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca
     6961 atggcaaaaa gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa
     7021 tattgaatta acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga
     7081 tgttttgctg aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga
     7141 tcagcttaaa gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc
     7201 tgaaacagac tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa
     7261 agtaatcgaa caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc
     7321 atttatgact ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga
     7381 tttcaaaatg gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga
     7441 catcgatgat aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga
     7501 atcacaatcg ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca
     7561 atatcctttc tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt
     7621 ttatcgttca ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac
     7681 ttaccctctc catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt
     7741 agatgttgct gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg
     7801 accaacaaat gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg
     7861 ttattttccc tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca
     7921 gcaagaaata gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg
     7981 gatgtcagag catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga
     8041 tgcaacacat gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt
     8101 taatgtatat caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct
     8161 atagatgttt tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg
     8221 atcgctgatt atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat
     8281 accaaaagag ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc
     8341 tttgtgacgc ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat
     8401 gagaacgagg caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa
     8461 cagatctcga tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa
     8521 gcggccgaac tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta
     8581 ggagcaatcg gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt
     8641 gatcctgaac tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca
     8701 gtgatcaatc atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac
     8761 ggatatgaag aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt
     8821 ctggaatggt ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa
     8881 aaatgatgga ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta
     8941 aaagttactt ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt
     9001 cacaaggaac aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt
     9061 cggaattggc aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc
     9121 acagtccttt tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt
     9181 aaaaattgct gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa
     9241 taaattaaat attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt
     9301 tgtatttatc tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac
     9361 tatataagtc atttgaaagt aaaaagatac tgtaaataa
//
LOCUS       DAFKHN010000093         9326 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFKHN010000093 DAFKHN010000000
VERSION     DAFKHN010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.093"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(143..1087)
                     /locus_tag="LY912_002426"
     CDS             complement(143..1087)
                     /locus_tag="LY912_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBM6956076.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDMD
                     KQVTFIEGDVSDSQLMERIMKEYQFAYIFHLAAVASVADSVERPVETHRVNFDSALLL
                     LELARKYQSNLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKAEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILSGMERYLKTEI"
     gene            complement(1221..2612)
                     /locus_tag="LY912_002427"
     CDS             complement(1221..2612)
                     /locus_tag="LY912_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBM6956077.1"
                     /translation="MLNERFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFVINIFIQFS
                     FIALSGSRTTLVCLLITTFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAHAWAHVPHITEVKKDTSDSSGTTSSNKVDLKRPDTDSGDVSNLRFELWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKALRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            2738..3148
                     /gene="tagD"
                     /locus_tag="LY912_002428"
     CDS             2738..3148
                     /gene="tagD"
                     /locus_tag="LY912_002428"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HBM6956078.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGHFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            3324..3737
                     /locus_tag="LY912_002429"
     CDS             3324..3737
                     /locus_tag="LY912_002429"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956079.1"
                     /translation="MISISHSIKELFTIKDKNIEINSFQETFYKDKKAIVIEGPLVRT
                     FRHCLFCKESAKQIEKNGKKISMIILNRSGNKQTYLRLRKQHYHCQSCGKYFTAHTYL
                     VAPSCFISKQVHYTILEELTERQALKTIAKRCDFQ"
     gene            3894..4151
                     /locus_tag="LY912_002430"
     CDS             3894..4151
                     /locus_tag="LY912_002430"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956080.1"
                     /translation="MTFCPAGEKKDLIAYFMRFTRKAHMGVRYIVTDMNAPYFSLVKE
                     PFPNAQIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKCQRHL"
     gene            4238..5476
                     /gene="istA"
                     /locus_tag="LY912_002431"
     CDS             4238..5476
                     /gene="istA"
                     /locus_tag="LY912_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBM6956081.1"
                     /translation="MRKDIREGVMIYVINEIKPNYAALAKQYDCDYRTVKHAYEEAQV
                     KESKPPERKKRPSKLDPYREIIQDKIKDQCSAYSIFKFIEHKGFGGSYSLVKTYCRQI
                     KQAKVHKATVRVEHSPGLSAQVDWKEDMRLISNQGEIFEFNIFLYVLPYSKKKYVTLT
                     FDRKQDTLFECLDDAFYQTGGVPKEIWFDNMKTVVDHSRSQFSKPHFNKRFYAFSKDA
                     GFTPIACRPFRPQTKGCVEALARTVDRLRVYNHEFYDAVELCHLVNNLCVELNNEVSQ
                     STDQTPDERWQTNEKEHLHPYQKNLLNPYFEDFIRRKVTKEEMVIFRKCRYSVAPRYI
                     GKEVEIELSDKEDQVQIYYNGELIRSHPLTTKQLNYHEEDYFQILKSDVMSHKEDDGI
                     RAYTRESLKQYDLVEVADEE"
     gene            5466..6206
                     /gene="istB"
                     /locus_tag="LY912_002432"
     CDS             5466..6206
                     /gene="istB"
                     /locus_tag="LY912_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBM6956082.1"
                     /translation="MKNSHYQELMTNLETLGLNHMREYVPNYIEVANREELSLTEALL
                     ELTRREVDHQNKQKMNRVVARARFSKRTSLEEFDFAFQPSINKREVLDLRHMGFVEKH
                     ENLVFIGSPGVGKTHLTIALGIEACRQGYRTLFITCHELLLRLRTAYEKGTLERVLKR
                     YARYDVLIIDEIGYLPIQKQEADLFFQLLAMRYEHRSTIITTNIVLSRWGELFQSSEI
                     AAAILDRLVHHVKVFKITGKSYRMRDKI"
     gene            6616..6780
                     /locus_tag="LY912_002433"
                     /pseudo
     CDS             6616..6780
                     /locus_tag="LY912_002433"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6847..8274)
                     /locus_tag="LY912_002434"
     CDS             complement(6847..8274)
                     /locus_tag="LY912_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBM6956083.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFLQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIAGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIILFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPLFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTALSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVVLFFIVNLTLTTSAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEVRKIIRK"
     gene            complement(8271..>9326)
                     /locus_tag="LY912_002435"
     CDS             complement(8271..>9326)
                     /locus_tag="LY912_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBM6956084.1"
                     /translation="SSFGGRNYSGNPRVISEKIHEKKLNYRIIWLIKKEAIITDLPDY
                     IKRIDSDSFLAAFYLYTAKYWIDDSRKTIKYAKRKKQFYFQTWHGTPLKKIEFDAKDK
                     LPKRYLSYAKKDSESITYLLSGNRYSSEKYVSAFNIVPSKILEVGTPRNDELASSKEQ
                     VFDLKKKQINVLFAPTFRNNIEDNGITQLEWLGVDNLREFFKKQQQELNLMTKFHPNV
                     HSKLATDSKSIEYMKKHQITLINDGIPLEMLFEEIDVLITDYSSIFFDFALTKKPIIL
                     FNYDEKEYSLERGFYIQLSELPIISVQDSYGLVDVFKNQQEKLLKSSQELLDYIGNYE
                     TGASTEKVLELLERDIK"
BASE COUNT         3246 a         1685 c         1460 g         2935 t
ORIGIN      
        1 aaagttctct ttttcatgta aaatatttaa ttatatattt cctaaataaa aagtaaaaca
       61 agaattaaat agttggttat acaactttaa ttcttgtttt actttttaga attatttatc
      121 caaagatgca atcatttttt catcaaattt ctgtctttaa ataccgttcc attccgctca
      181 atatatcaaa tttaggctga tagcctaaag aacgaatttt tgaaatatcc gctaaggaat
      241 cacgaatatc ccctgaacgc tccgcttcat atttaagcgc tagctctgtt cctaagattt
      301 gatcaattga atggatcaat tcaagtagcg tagtgctttt tcctgtaccg acattgaatt
      361 gctgtcctaa agctttttct tccttggcaa caagtaaaag tgcttgtata acatcttcta
      421 tataaacaaa gtctctagac tgactcccat cgccaaataa agtaaattcc gctttttctc
      481 ctgccaattg ttttttgtaa cgatccacta gaatcgaaat gactccgcta tatggagagt
      541 ttggattttg atttggacca taaacgttaa aaaatcggac agcactagtc ggaacatcat
      601 ataaatgaca gtaatccaaa acatattgtt ctgctgcaaa tttatcgata gcatatggtg
      661 ttaatggacg gatgactgat tcttcttttt ttggcagtgt tggttcatca ccataaactg
      721 cagctgatga actaaatact aatcgtttta aattagattg atatttccgt gctaactcaa
      781 gcaataaaag cgcactgtca aaatttacac gatgtgtttc tacaggccgt tctacagaat
      841 ctgccacact agctacagca gctagatgaa aaatataggc aaactgatat tctttcatga
      901 ttctttccat caattgagaa tctgatacat ccccctcaat gaaagtcact tgtttatcca
      961 tatccaagtt ttcttttttt cccattgata aatcgtcaac tactacgatt ttgttttctt
     1021 ttcccaaata attcgctagc gttgaaccga taaaaccagc tccgccagta atcaatatag
     1081 tgtccatcaa attcactcca attgcacatt ttcgtatcaa ataatattag tttaccattt
     1141 ttatattgta aaaactataa aatttgttga agttgggata actagttttc ttttctactt
     1201 tcatatacct aaaaatagtt tcaattagtt actccttctt ctttagatat agttttttgg
     1261 atagaaccca gatatcccca aaaaataaat gaacctatcg tactaaccaa aatgagttct
     1321 gtgataaata atgccgaaac tgctattgta agaatcatta aaatagcaaa aaagtgctta
     1381 tcttttacta gatttggttg tgtgaaacaa taacgcaagg ctttaaagca ttggataaat
     1441 aagaaggtta acaatgtcaa tagacctaat cctcctgtag cagccatcac taagaaaata
     1501 aaattatgag cagttaaagt atcttttccc attaatgtat atggtagttt atcatgtgca
     1561 tattcaatat agtagcctgg agaacctccg gatatcggct tactcttgaa tatttcaatt
     1621 gcacttttcc aaagttcaaa ccttaaatta gaaacatccc cgctatcagt gtcagggcgt
     1681 tttaaatcaa ctttattgct gctagttgtt cctgatgaat cagatgtatc tttttttact
     1741 tctgtaatat gcggaacatg tgcccatgca tgagcagtta tatctgttac ataatacatc
     1801 gcaattatac ttagcaatcc tactactaat gcagttagcc atctttttaa agtattagtt
     1861 ttaagaaaac gactactata acttgtaaag aaactaaaaa caaaagttgt tattaataaa
     1921 caaactaatg tggtgcgtga acccgataaa gcaataaacg agaattgaat aaaaatatta
     1981 attacaaaaa atattttaaa tagaagattt aaatgcttgt aagtgaccaa ataatatata
     2041 gcaataatga tgacgattaa tgatataacc gcaccaaaat ttggatctgt atatacacca
     2101 aataaacggt tgcctaacca ccctaaacga actgggtaat acttatattt tattggaatt
     2161 tttatgccat attgaatgac aaaccagtat aatgatacta aattagctaa aaaccatacc
     2221 aatgaaagta tccaggtaaa tactttgaaa aaaaagttac tactatagtc tttgccaaac
     2281 tgataaatca taaagaaaaa gattaattgc cacatgatta acttaatatt ttcgctatat
     2341 ccatatttta aattcattaa actgcttact agcatcgcgc caataaaagc aattaatagc
     2401 caatcatatt tttttagatt tttttctcta aatgcaataa ttgcatctat aatgatcaag
     2461 acaactcccg ctattccagc aggccaaaaa agtaaagtat catatctagt aggtaatagt
     2521 aaatacgggc ctattgctcg taacattaaa ataaaaccaa aataaataaa ataccaacct
     2581 ttcacatatt ttaaaaatct ttcattcaac atttttcctc catccaccta tttctcataa
     2641 atatttctta tcctttttag gataaactgg tcctttcaat tctaacaaaa aaatgctaaa
     2701 ctaacaatgt atattaatga atttcgagag gtgaaagatg aaaagagtaa ttacttacgg
     2761 tacctttgat ttgcttcatt acgggcatat caatttactg aaacgagcaa aacaatacgg
     2821 agactatctt attgttgccc tttctacaga tgaattcaat tggaatgcga aacaaaaaaa
     2881 atgttatttt agttatgaaa aaagaaaaca gttacttgaa gctattcgct acgttgattt
     2941 agttattcct gaagaaaatt gggaacaaaa agtaaaagat ataaaagaat accatgcaga
     3001 ttatttcgtg atgggcgatg attgggctgg acattttgat gaacttgaac aactaacaga
     3061 tgcacaagtg atttatttac caagaacacc tgagatctct acaactcaaa taaagaacga
     3121 acttaattct ttaaatagtg ataaataata ttttttaaac aataaaagaa caatatatct
     3181 ggataagacg taaaaaaatg gctctataat ttctaggact gatagaattt tctgtcggtc
     3241 ctagattttt tgtaaaaaaa aacagacata aaaaaattcc gatagaatag agtcgtctaa
     3301 aacatcaatc tgaaaggaag tttttgatat ccatttctca ttctatcaaa gagctcttca
     3361 ctattaaaga taaaaatatt gaaattaatt cttttcaaga aactttttat aaggacaaga
     3421 aagccatcgt aatcgaaggt ccattagttc gcacttttag acattgtcta ttttgtaaag
     3481 aatctgcaaa gcagatcgag aaaaacggca agaagatttc aatgattatc ttaaatcgca
     3541 gtgggaataa acaaacctat ttgcgtctta gaaaacaaca ttaccactgc caatcatgcg
     3601 ggaaatattt tactgctcat acgtatcttg tcgctccttc atgttttatt tcgaaacaag
     3661 ttcattacac gatattagaa gagttgaccg agcgtcaagc attaaagaca attgcgaaac
     3721 gttgtgattt tcagtaacga cagttcaacg gacattatct gctctatcgg caacgctgcg
     3781 acagaagcta gactatttac ctcattgttt actattcgac gagtttcgct ctctttcaat
     3841 tttccatggg aagttctcct tttcttgtat gaattgagag acagggaagc tctttgacat
     3901 tttgtccagc cggagaaaaa aaagatttga ttgcttattt catgcgtttt acaagaaaag
     3961 ctcatatggg ggttcgatac attgtcacag atatgaatgc cccttatttt tcattagtca
     4021 aagaaccctt cccaaatgca caaatcatca ttgattgctt tcacattggg caacacttga
     4081 acaagttttt cgatcgtgtt cgaaaacgtg tgatgaagca gttgaatcaa aaatgtcaac
     4141 ggcaccttta aaatgtagga aaacggcaat ttaaaattgt tggtttacct acatttttgt
     4201 atgctcttct tatcccaaat gaaatggagg ctcagggatg agaaaagaca tacgcgaagg
     4261 agtgatgatc tacgtgatca atgaaatcaa acccaattat gctgcactag caaaacaata
     4321 cgactgcgac taccgaacag ttaagcatgc ttacgaagaa gcccaagtta aagaatcaaa
     4381 acctccagaa cgtaagaagc gtccaagtaa gttagatccc tacagagaaa tcatccaaga
     4441 caaaatcaaa gaccaatgca gtgcttacag cattttcaag tttattgagc acaaaggatt
     4501 tggaggaagc tacagtttag taaagaccta ttgtcgccag attaagcagg cgaaagtaca
     4561 caaggcaacc gtccgagtcg aacatagccc tgggctttct gctcaggttg actggaagga
     4621 agatatgcga ctaatcagta atcagggcga aatttttgag ttcaatatct ttttgtacgt
     4681 cttgccatat tccaagaaaa aatatgtcac actaactttc gaccgaaaac aagacacact
     4741 ctttgagtgc ttagatgatg cgttttatca aaccggtggc gttcccaaag aaatctggtt
     4801 cgataatatg aagacagtcg ttgaccattc tcgtagtcag ttttccaaac cgcatttcaa
     4861 caaacgtttt tatgctttca gtaaggatgc cggcttcaca ccaattgcct gtcggccatt
     4921 tcgtccgcaa acaaagggct gtgtcgaagc tttagccaga actgttgacc gcctacgggt
     4981 ctataatcat gaattttatg atgccgttga gctgtgtcat ttagtgaata acctttgtgt
     5041 tgagttaaat aacgaggttt ctcaatcaac tgatcaaaca ccagatgaac gttggcagac
     5101 gaacgaaaaa gagcacctgc atccatacca aaaaaacctt ttgaatccct attttgaaga
     5161 ctttattcgc cgtaaagtca ccaaggaaga aatggtcatt ttccgtaaat gcaggtactc
     5221 tgtggcgcct cgctatatcg gtaaagaagt cgaaatcgaa ctctccgata aagaagacca
     5281 agtacaaatc tattataacg gagaactgat tcggtcgcat ccattaacga caaaacagct
     5341 gaactaccac gaggaagact atttccaaat cttgaaatcc gatgtcatga gtcacaaaga
     5401 agacgatgga atcagagcgt atactcgtga aagtctcaag caatatgatc tggtggaggt
     5461 tgccgatgaa gaatagccat taccaagaac tgatgaccaa cttagagact cttggtttga
     5521 atcatatgcg ggaatatgtt cctaactaca tcgaagtggc caatcgagag gagctttctt
     5581 taacggaagc tcttctcgag ctgacacgca gagaagttga tcatcaaaat aagcaaaaaa
     5641 tgaatcgtgt ggtggcacgc gcccgctttt ccaagagaac cagcctggaa gagtttgatt
     5701 ttgccttcca gccaagtatc aataagcgcg aagtgctaga cttaaggcac atgggctttg
     5761 tggaaaaaca tgagaacttg gtttttatcg gcagtcctgg tgtaggcaag acacatctga
     5821 cgattgcatt gggaatcgaa gcctgtcgtc aaggctatcg gacactattc atcacctgtc
     5881 atgagctgct tttgcgtctg cgaacagcct atgaaaaagg taccctagag cgtgttctca
     5941 aacgatacgc tcgctatgac gtcttgatta ttgatgagat tggctatctt ccgattcaaa
     6001 aacaggaagc tgatttattc tttcagcttc ttgccatgcg ctatgaacac cgctctacga
     6061 tcattacgac gaacattgtc ttatctcgtt ggggggagtt gttccaaagt tctgagatcg
     6121 cagctgccat ccttgaccgt ttagtacatc acgtcaaggt gttcaagatc acaggcaagt
     6181 cttatcgtat gagagacaag atctaaagtg tcgattgtcg acaattacta ttgccgaaaa
     6241 cctacatttt tatcctgccc aaaacctaca attttaagct gcccttgaca tcaaaaagac
     6301 acttcacaag ctaagtgcta tcgacaattg aaacctttgt ataaattact tctataatca
     6361 gatgacgagt tggattatac aacattcaag aaatggcaga attttcaatg gcgctattta
     6421 acagaaagtg aagtagttga ttgtctaccc tcaatctctt atgaacttaa aatggcttag
     6481 cagtattatc aaaagctgct taacaattat cacaagaaac agctagctac ttcgagaaat
     6541 gaccaaagaa gttccctcga aacttcacta tcttaaaaag cctttttcat atctgaaaaa
     6601 ggcttttaac tagcattttc gaaaaagtat tttaatacaa aattagagaa tcttcgcaca
     6661 catatcaaaa cattgaaacg atttgcttat ggattttgca gttttaccaa tatgcgcttg
     6721 tggatttttc taatcaacgg gttaataagc tatgcattaa aagctagtaa atcttactaa
     6781 ctttgttgat cataaatgac cttatcagcc cgatttgaca aagaactact tttttacaac
     6841 attattttat tttcgaataa tctttcttac ttcatttcgt atatctggaa aaagaaaata
     6901 aacaaacgga agataaataa tgaaaatcat tattgattta attgccatat ctaaaaatga
     6961 agaagagaat aattgtggaa gaaagtaata ggccgaagta gtcaaagtaa gattgactat
     7021 aaaaaataag acaacgttct tcccaaagaa ataggatatt tttatttctt ttcgtacaaa
     7081 aaatactcta aagaaaaaga ctaataattc tactaccacg agtacgattg tagccgctac
     7141 agcgccataa gtaggcacaa aagctacatt tccaataata cttacaatcg caccaatgat
     7201 cattggataa gcatactcct tatctttttc tatagcaatt gcaaattggt tagcaaaaac
     7261 tccaccaatt ggactaacaa ctataattag acaagaaata agcatgttta ttgtcatcgg
     7321 tttgaaattc tccccaaaaa accatggaac aaattctttt gtattgataa acaccacact
     7381 aaaaagaatt aatgcaataa taatcgtgta atcaaaagat ttttttgtgt aaactaaaat
     7441 attttctgat tttccctctg cctgtgcttt agatatttta ggcaacataa caatagtaat
     7501 tgatgttaag actgccaata taatacgagc aattttttga gactgatcat aataagataa
     7561 tgctgttgga tccacaaaat acccaactat cgttttgtct aaagttgtgt acacttgcat
     7621 aaacaactga ggagtcaaaa taataaaagc tggtttccac aactgtttaa aaacattaga
     7681 gttaaagagt ggtttaccta cttttccgtg gatactcaac cagaaaacta aacttcctaa
     7741 aaagttagta attgaagtaa tgaacacata aatccacaaa tcatctttag ttgaaacaaa
     7801 aaggattatt aacaataccg atgataattt gataactgta tttctaataa ccactttcga
     7861 aaattcttca attccttgaa aaaaccaaga aatatctaat gttagccctg caataaatat
     7921 caattgaatt aagtataaat ttttatactt tacatcaaaa aaataaatat aggctatata
     7981 gagaaaggaa acactcaagc ctattaaaaa ttgaagaaag taaatattcc agaattgtaa
     8041 agatagtgct tttttatctt tccttgattt agcgatattt cgaatacgaa aaggattcat
     8101 tcccacagca atgacagtca ttaaaaattg tgatattgag aaaacatacc cataaatccc
     8161 taaaccagtt gaacctattc tacgactaag tataggtata gtaagtaagg gcaaaacaat
     8221 caaaaagact tgatatatcg cattataaaa tatatctttt actgtttttt tcactttata
     8281 tccctctcta acaactcaag aaccttttct gtacttgccc ctgtttcata atttccaata
     8341 taatcaagta actcttgaga acttttcaaa agcttttctt gttggttttt aaaaacatca
     8401 acaaggccat aactatcttg tacgcttata attggtaact cacttaactg tatataaaaa
     8461 cctctttcta agctatattc tttttcatca tagttaaaaa gaataattgg tttttttgtt
     8521 agcgcaaaat cgaaaaaaat agatgaataa tctgtgatta aaacatctat ctcttcaaaa
     8581 agcatttcaa gaggaatccc atcattaatt aaagtaattt gatgtttttt catatattct
     8641 atacttttag aatcagttgc taatttacta tgaacattag gatgaaattt agtcattaaa
     8701 tttaattctt gttgttgctt tttaaaaaat tcacgtaagt tatccacacc taaccattct
     8761 agttgcgtaa ttccgttgtc ctcaatatta tttcgaaaag ttggagcaaa taagacattg
     8821 atttgtttct ttttcaagtc aaacacttgc tctttactag aggctaattc atcgtttcta
     8881 ggagttccta cttctaatat tttagaagga acgatattga atgctgaaac atacttctca
     8941 gaactatagc gattaccaga taataaatat gtaattgact cactatcttt tttcgcatag
     9001 cttaggtaac gtttaggtaa cttatctttt gcatcaaatt caattttttt taaaggcgta
     9061 ccgtgccatg tttgaaaata aaattgtttt ttcctttttg catacttaat cgttttccga
     9121 ctatcgtcta tccaatactt agctgtatac aaataaaagg cagctaaaaa agaatcggaa
     9181 tcaattcttt taatataatc tggtaaatca gttataatcg cttctttttt gattaaccaa
     9241 ataattctgt aattcaattt tttttcatga attttctctg aaataactct tggatttcca
     9301 gaataattac gcccgccaaa acttga
//
LOCUS       DAFKHN010000094         9321 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFKHN010000094 DAFKHN010000000
VERSION     DAFKHN010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.094"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            273..1499
                     /locus_tag="LY912_002436"
     CDS             273..1499
                     /locus_tag="LY912_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956085.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            2349..3674
                     /locus_tag="LY912_002437"
     CDS             2349..3674
                     /locus_tag="LY912_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBM6956086.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            3667..4014
                     /locus_tag="LY912_002438"
     CDS             3667..4014
                     /locus_tag="LY912_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956087.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            4329..5186
                     /locus_tag="LY912_002439"
     CDS             4329..5186
                     /locus_tag="LY912_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBM6956088.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAERYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            5206..5766
                     /locus_tag="LY912_002440"
     CDS             5206..5766
                     /locus_tag="LY912_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HBM6956089.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            6732..7499
                     /locus_tag="LY912_002441"
     CDS             6732..7499
                     /locus_tag="LY912_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HBM6956090.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            7525..8070
                     /locus_tag="LY912_002442"
     CDS             7525..8070
                     /locus_tag="LY912_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956091.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            8071..8637
                     /locus_tag="LY912_002443"
     CDS             8071..8637
                     /locus_tag="LY912_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956092.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            8652..8900
                     /locus_tag="LY912_002444"
     CDS             8652..8900
                     /locus_tag="LY912_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956093.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            8920..9159
                     /locus_tag="LY912_002445"
     CDS             8920..9159
                     /locus_tag="LY912_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956094.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
BASE COUNT         3531 a         1235 c         1815 g         2740 t
ORIGIN      
        1 atacaattat ttctcgagat gtatagatag aaagttactg tttaaaaaag aaggattaga
       61 atttagtttt gatgaagatg aatttgaaaa attagtgatg gactggcgta agaatttact
      121 ggatacggta caattctaaa agcaattgag gtcgaaattc cgatacttga atcatgatct
      181 atattatcgt gttatgagtg aaatttctaa taaagataag atatttcatt tggacagtca
      241 tgtgaatatg agcttaacaa ttaaacgtat ttatgatctt ttatatgttt ataaacatta
      301 atgaggtgct aaaattgaca acaataacta tgacaaaaaa aatagaagta tatgttgatg
      361 gatcacaaga agaaagggat tccttttttg attttttttg gaaaaatagt agagaatatg
      421 taaaagcgtt gaatctggta tataaacagc taatgtttga agagttgata aaagatgcaa
      481 ttaaagaaat ggatcaaggt tatgctgaga gagaagaaag tattcaaaat cggattgaaa
      541 agttagcata tactgatcca atagatcaaa aaaaacttga taaagcaaaa gctgaattat
      601 ctaaattgag aaatgaaaaa aataaagaag cgagagaaat attaacgcaa gcgatagggt
      661 tgaagagtca aacgagaaca cgagatgtag caaaaaaatt agactttgac tttggagatt
      721 ttgttgattc cgcaaatatg aaagctagta aagattttgg caatgatttt atcggaattg
      781 tgaccggaca aagaacgcct agaatatata aaaatagaaa caaatatgga ttactacctt
      841 ttagaggtcg agatattaaa atccataaag atgataagtt ttatatttat ttacctaaag
      901 gctttaggtt taaagtgaat ttaggtagca agccaagaaa agcaagagat gttgcttcag
      961 ttttacaaca cattatggat ggcgattaca aattaaatca aagtaatctt atttttgatg
     1021 gaagaaaatt attttttaat ctaacaattt cttttgaaaa aagctataat gaaatggaat
     1081 tcaagaaagg taatgaattg atcgtaaact ttgcagattt gtgtagcggt gaatgtttaa
     1141 ttaatgataa atctgtaatg tcttttggtg atagccaata tataagaaac ttcaaaagta
     1201 aaattttagc aatgaaatca aaagaacaaa gccgaggagt cttttctaag ggcggtcatg
     1261 gtcgaaaaag aaaattagat caagatcgat gggaagcaat aaagaaaaga gaaagtaatt
     1321 ttgttaaaac ttataataat caatgttctg caaaaatcgt taaaactgct attcgcaata
     1381 aagctcaaat tattcgtatc attgaaccag ataaggctta tggcgaatgg gcttactatc
     1441 aattgaaaga acaactagta aacaaaggaa aaagatatgg gatagaagtc agaagttagt
     1501 aaattaaaca atcgttgatt tggcaacgaa atagtgaggg aaaatccact cactgaaggg
     1561 taaactccgt caagttgtgt gaccagacgg aaggacgaat gttgttgagg ttttagaacc
     1621 atataaaaca gcatgtttct caaattttta ggataaggga aattgctagc agtttgtttt
     1681 agaaccatat aaaacagcat gtttctcaaa tgagtacttt aaattaattg atggcgttcc
     1741 tgctttagaa ccatataaaa caacatggat ttaaaacaag aagtaagtca gttctccttt
     1801 tactttagta aggaaaaata aagtattctc aataaaactt aaaataagca aacctttgtt
     1861 ttaatagcta atcgaagtaa aacccaaagc catatgaacc cctgaatcag cgaaagttta
     1921 tgatgatttg gattactaat agtttaggaa ttagatggta aatctaaatt aaacaatcgt
     1981 tgatttggca acgaaatagt gagggaaaat ccactcactg aagggtaaac tccgtcaagt
     2041 tatgtgacca gacggaagga cgaatgttgt tgaggtttta gaaccatata aaacagcata
     2101 gttctcaaat tgtttaaaat gattgtcaag ttaaaaaaat ctgggatcat ataaaatagt
     2161 atagttctca aatatgatta gaaaccctat taaagagcaa tattaagcca acttacttaa
     2221 atcgtttaat taagaacaat aatctctttt agtcagactt ttagtctgac ttttttgtat
     2281 ttccaaaatt tattctttac aaaaacgaac atacgtttgt ataattgctt gtgaatgggg
     2341 gaataaaaat gtttgattac agtagagaac cggtgaatga ctatttttta atcgacatga
     2401 agtctttcta tgctagcgtg gaatgtattg aacgaaattt agacccaatg actacaccgt
     2461 taattgtcat gagtagatcg gacaacactg gttcaggtct gactctagct tcttcaccta
     2521 ctgcaaagaa aaaatatcat attactaatg ttagtagagc tactgattta ccttatccat
     2581 taccaaaaga acttcatatt gttccaccac gaatgaactt atatataaaa aaaaatatgg
     2641 aagttaatca gatttttaga aagtatgtcg cagatgaaga tttattgatt tattcgattg
     2701 atgaatcaat tttaaaagtg acaaaatcct taaatttatt tactagttca ggaacaagaa
     2761 gcgagagaag aagagaatta gctaaaataa tcaaagatga gattcagaaa gaaacaggtc
     2821 taatagcaac agtcggaata ggagataacc cattattagc taaacttgca ctggacaatg
     2881 aagcgaagag tagtaaagaa tttatagctg agtggactta tgagactgta cctgaaaaaa
     2941 tatggaaaat aaacgagatg actgactttt ggggcattgg atcacgcatg aaaaaaagat
     3001 tgaatcatat gggaattatg agtatagaag atttagcaaa ttggaatccc tacacaatta
     3061 aaagtcagtt aggtgtaatc ggactccagt tatatttcca taccaatgga attgatcgta
     3121 cggatattgc tattccacca gaaccaacca aagaaaagtc ttatgggaat tcacaagttc
     3181 taccaaaaga ttatacgagg agagaagaag tagaactagt agtcaaggag atggcagagc
     3241 aagtagccat tcgaattaga caacacaatt gcaaaactgg ttgtgtacgc ttagcaattg
     3301 gtacgtcaat tttggaagaa aaatcaggtt tctcgcacca gatgaaaata ccaattacag
     3361 ataatacgaa agaattacaa aattattgtc tttttttatt caataagttt tatgaggggc
     3421 aggaagtacg acatatagga gtaacttata gcagattagt atacacagat tccctacaat
     3481 tagatttatt tagtgatcca agaaaaaaga ttgctgaaga aaatttggat aggattattg
     3541 ataagattag acaaaaatat ggatttacag ctattataca tgcttcatct atgttagaag
     3601 gtgcaagaag tattacgaga agcactttaa taggaggaca cgcaggagga ttaggaggtt
     3661 tgcataatga ttgaatataa cgatagagga cgtttaaaat ggtcgggatt ttatttgtct
     3721 gatcatactg aaagaatcaa tgcagacaat gtacaacgtg ctaatcataa tttggcaaaa
     3781 gaacaaatga cgactgaaga gattgcgaaa atactgagaa ctgctgtcat aaaaaataga
     3841 cccgtctgca ttcaaaaaga ggaacgaaac gctgaaggtt actatccaga tgatgtagta
     3901 ggaaaaatta ttggatatga cgagcttggt gtatttgtgg aagaagaaaa agttcactat
     3961 gatgaaatta ggaatgtttc tttctcggaa ttattaaaat ggagtcagat atgaacatta
     4021 ttaaaaaata cgaattcggt tatattacgt atgaacagct aatagaggaa ttatggggat
     4081 atggtcaaca attaattaat gaagtgggga ttgattgctt ttgtttctat attgaatccg
     4141 gagcaggata ccataagaac agatactata tatttccata tccaccaaaa tagtctctta
     4201 gatattttta aattttctcc aaatactttc aattattgtg aaatatttcc ctttaattaa
     4261 tcaaattttt tataaaagta atatataaaa taaattgctt gaagtattat atttagatat
     4321 cataatttat ggaagaaaaa ttaattaaaa aggatgagat tataatgggg ttactggttc
     4381 cgagagctaa tacttatact atacctttaa cgaaacgcca attaattgct gaaagatatc
     4441 aaaggattac tagagccatc aatagagagt tttggaattc tgaaagtgat actgctcaca
     4501 gtttatacgt aggttcttat gggagaggaa cggcaattag tactagtgat atagatataa
     4561 tagttgaatt accgatggca gaatttgaca gattcaaaaa ttatttatca aatggcccgt
     4621 ctaagttatt acaagttata aaaaacgcat ttcaggaaat actaccaaat agtgatatta
     4681 gagctgatgg acaagttgtt aaaataaatt tccatgatgg aatcaaattt gaaatagttc
     4741 cagcttttaa tgaaaaagat tattggggtg agtcaaaagg gtttatttat ccagattcaa
     4801 acatgggagg gaactggaaa gctacaaatc ccaaaaaaga gcaagaagcc atgaaattaa
     4861 agaatacaaa aagtaataat ttattatatg ctacgtgtaa acattttcga catgtacgag
     4921 atacagaatt tacgagttat catctttcag gaatagtaat tgacagtttc gtatatgagg
     4981 ctatgggaaa ttggaaattc gttgaaaata acagtggggg tcaaaacatt agttctgtat
     5041 cttatgagac agctttatta gaatactata actcacataa agttatgggc ggtttaaatt
     5101 tatactctcc tggaagcaat caatttgtta attctgatag tagtatcata tgtttagaaa
     5161 aagtattaaa aaaaatagct ttataaagtt ttatggagga acaacatggg agacgaaaaa
     5221 aagcgcttgg aagttcaatt acgtgaagca tatggacgag taacgtatac ttacaccact
     5281 catttaaagc aagccgataa tattatttct gacaataaaa ttttaaggtg tcttcaaatt
     5341 ggtttgtcag cccttactac tggaggggta cttagtacca ttattactga taatagtgag
     5401 ttaacctttg ttgctggatt atgttcaaca atttctcttg gattaaactt atactttaag
     5461 aattttgatc ttgctgaaga agctaaaaat catcaaattg ttgccgataa attatggttg
     5521 atcagagaag aatacgtaag cttactaaca gatttaaatc gtttaagtgt tgaagatatt
     5581 gtgaaaaaaa gagatcaatt aatgaacgaa actcatgaag catataaaaa tgcccctaaa
     5641 acaaatagta aaagctatga atcagctcag aaagcattaa aatctgaaga agagcaattt
     5701 tttacagaag aggaattgga taagatgtta ccagagcatc ttagaaaaaa gagttctaaa
     5761 tattgaactc tttttttatg cttaaaattc tcttgtaatt tttctattca tctatattta
     5821 agaagaaata tgatgataga aacatctcct aaagccaccg caagccgttc taagcatagc
     5881 ttagcccgac attgctagat atgctcatct caccatgaac gtttcctaaa gccaccgcaa
     5941 gccgtcctag ccattgccta gtccgacatc gctagattag tgcatctcgc cataaaagtt
     6001 ttctaaagcc accgcaagcc gtcctagcca ttgcctagtc cgacatcgct agattagtgc
     6061 atctcgccat aaaagttttc taaagccacc gcaagccgtt ctaagcatag cttagcccga
     6121 cattgctaga tatgctcatc tcaccatgaa cgtttcctaa agccaccgca aaccgtccta
     6181 gccatcgcct agtccgattt tgcttgatcg gttccatttc tgtttattta gtgggtcaac
     6241 accgtaatct taaatagcca tcgcctattt aagattacta ggtctgcttt gaaggtaaaa
     6301 agtctttcat tcttcaagac ttttaggctt tcaagctacg cctgaaagca ttgaaattca
     6361 tcgctcttta tttggttttg ccatttataa ttccttacgc ccattatctt tttcgcctgt
     6421 cataccttgt cagaagtgtt tagagcttat ctcatctttg gattaataca agtggcgtaa
     6481 atttttttct aaacgcaagc gttacgaaaa taatttactt aaacacttgt attaatccgg
     6541 cagataagaa cgcattctaa tcactcccga caaggcaaga caggcgaaaa agataaataa
     6601 atgaacgaaa ggaagaaaca taaaatgcaa aaccaaatag cgatgaagaa aaaaccacct
     6661 ccctctaaaa caatccaaac aaaaaagaat tttgaaaaac caaaaatcaa aaacagaaag
     6721 aagcgttcaa catgagagat agaattttag aagttaatca agaaatggta aacaagttaa
     6781 caaatatcag tgggaactat gaaaagtacg atggtacttt acttgataac tatatttttc
     6841 acgatacaca aaatatcaga attggcagaa gtaaaccgag agcgttcatt ctcatcaaag
     6901 agaaatattt gaatgaatgg aatagcacct atgaaatggt tatgactgat aactttgaaa
     6961 aggtattgga tttcagaaat gctttgttgg gttctgatat gggaaatagc agtcttgaat
     7021 ctattgaagt tgaaaacaag accgagaatg aaggtgaagg attgattaag aatgtcttga
     7081 aaatcgaaca aaaatatatc agtgaagata gaagttttta tagagtcaca agctcggttg
     7141 gtctagcaaa ctttgctact aacttaattg gaaacaatgc tagtgaatct ttgctagtga
     7201 tgtgtctgaa tacaaagaat gaggtcattg cttatagcga agttttcaaa ggtggaatta
     7261 atcaatcagt agcgatacca agagagattt ttcaactagc tttgctaaac aattcagcaa
     7321 aaatcgcagt atcacataat catccgagcg gatatgaatt tccaagtgaa aatgacaaaa
     7381 gttttactac gaatttgaaa aacgcaggaa aaacaattgg tattgaattg ttagaccata
     7441 tcatcgtaac aagtaaaaac acaagctatt actcatttca agaaaatggt tctttataaa
     7501 aattagagaa aagaggaaaa caagatgggc gaaagaacac aagcgttaat tacagtcaaa
     7561 tatggtaaca gcaaaacgaa agcaagcgtg tcgattcatt atcagtgggg gtatggtcga
     7621 tatatgctga tggacgtatt gaatcaagga atttatttaa tcaataaagc atacgactta
     7681 cgagataaat caagagaaga attagcaaaa ggaatctttg atagaagtac aggagttatc
     7741 aattttgtta cctatgaatc tggagtgagt gcttatgatg aaacagggtt tggtgggcgc
     7801 tatgaacctt atcaagaaac gattgaagat gtgatgaagt tttcagataa caatgatggc
     7861 tatgctcatt tagagatggt gttcgatgaa aatggattta gtctagatga taaaaccaga
     7921 ttgcgattgt ttgattttga gggtcaacag ataggactaa acaagttttg tgaaagcgga
     7981 aaagagtttg ctacgaaaga ttttattaag ggatacagat tattgctaga aaattatgga
     8041 ataaacctag aagaagagag cgtgaaataa gtgtttgaaa aaagaaaaga ccagttccct
     8101 aatttagaag cgaaaagtca aaaagtgatt gatggtgaaa tgattgaatt attccaaaaa
     8161 agttatggaa ccatagaaac taccgcaagt tgcaaatact actttcaagg aaagagaaac
     8221 acgtttaaag gctttgccga ttctgatgaa gaattggcaa agaaaatcat tgattggctt
     8281 gtcagcagtg aacacgtagc aagggaagat accgttagaa caacgattaa tggggaagtc
     8341 ctaacaggta ctagatgtgt ttgttgtaat catgaatttg tagaagatga aggttgctac
     8401 cgaatcaatg aatatggtga ttttatttgc cagagttgcc acgagataga atttccaacc
     8461 gaaagaagtt ggtttgaata catgctacaa gattatgaga tggaaaaaga aaatggtgaa
     8521 gtagtttttt gtaccaaaga ggaattgagt aagagaagcg atgatgaaat tgaagattgg
     8581 tgtgtgtggt tagtaggggc agatgattgc gttgcatatt acacaacagc agaataggag
     8641 tgtgaatcag catggaagga atggattttc tagatcatga agatttggtt gattttggtt
     8701 atacatggaa aggaatggta ggtattagca gaagtcttgc taatgccttt tacgaaagaa
     8761 attatgcagt atatgttctt tatgatgacg atacagaaag ccttgttgac gaggaatata
     8821 aattggattt agagaatgtt ttatatggaa tagaaaagga agatttagca aaatatattt
     8881 tttcatggtt gggtcaataa gtgaaaggaa gatagaaaca tgacaaaatt taaaagtaag
     8941 ggtatgcaat ggtgttctta ttattatgtt ggaaatgatg aagatttatt gagaaaaacc
     9001 caacgaaaag gttatccaga taagatattg aaacaaatag gttattacat gccagaagag
     9061 aggatagaaa aagaattttg tgaggttctt tttgatagtg aacagctatt agttttgtta
     9121 acccaaaata aattgatttg ccaatttgaa aataattaag atgaggtggt gaaccatgaa
     9181 tgaagataag atggtattaa gtgaatatgc tagattgaga actattaatt ctttagcatc
     9241 tcatttaagt tgttctttcc taacaaaggt gctaaaatta atttacaaat gtgaagattt
     9301 tgtacaagag aagcacaaag a
//
LOCUS       DAFKHN010000095         9132 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFKHN010000095 DAFKHN010000000
VERSION     DAFKHN010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.095"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            19..771
                     /locus_tag="LY912_002446"
     CDS             19..771
                     /locus_tag="LY912_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBM6956095.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(865..1470)
                     /locus_tag="LY912_002447"
     CDS             complement(865..1470)
                     /locus_tag="LY912_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBM6956096.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(1526..2500)
                     /locus_tag="LY912_002448"
     CDS             complement(1526..2500)
                     /locus_tag="LY912_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBM6956097.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(2878..3597)
                     /locus_tag="LY912_002449"
     CDS             complement(2878..3597)
                     /locus_tag="LY912_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6956098.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(3724..4995)
                     /gene="celB"
                     /locus_tag="LY912_002450"
     CDS             complement(3724..4995)
                     /gene="celB"
                     /locus_tag="LY912_002450"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBM6956099.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            5148..6545
                     /locus_tag="LY912_002451"
     CDS             5148..6545
                     /locus_tag="LY912_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBM6956100.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            6626..7066
                     /locus_tag="LY912_002452"
     CDS             6626..7066
                     /locus_tag="LY912_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBM6956101.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            7213..7539
                     /locus_tag="LY912_002453"
     CDS             7213..7539
                     /locus_tag="LY912_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBM6956102.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            7540..8289
                     /locus_tag="LY912_002454"
     CDS             7540..8289
                     /locus_tag="LY912_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956103.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(8315..8725)
                     /locus_tag="LY912_002455"
     CDS             complement(8315..8725)
                     /locus_tag="LY912_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBM6956104.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         2916 a         1646 c         1847 g         2723 t
ORIGIN      
        1 gataatggag gggtcattat gtcagatgga cgtatgttat ttgagagaga acgacaggac
       61 atggcacgta tcgtaagagt gattttcgaa aggaaaaaca caaatgtcgc aggagggaat
      121 ttttccttta aaaccactga tgatcaaggg aaagactaca tcatcatgac gccgaccatg
      181 atgtcagaag cctatctagg agagatttct cctgcacagg ttctagtagt agaaccaaga
      241 acgcgtagaa tcgttgacgg agtcggtcat ttaactcggg agatcaatat gcatgaagcg
      301 atgtatgaga ctaatccagc tatcaaagct gtcctacatg ctcatgcgcc taatgcaatg
      361 ttctgggcga ctactgggtt gcctatgcct aatttgacag aagccacagc taaagtaaaa
      421 gagattcctg tcatggactt tgagcctaat tgctctgaag aacttgctga attgacaagc
      481 gactatgtaa aaaaacagca tctcgaatta ccgcatatgt tgctgctcaa ctctcatggc
      541 gtattgatca acacaggtgg agaatcagga atcgaagcta tccataaagc actgcaaatc
      601 cttgatacag ttgaatggaa tgcagaaatt gcctacaagc agacgatttt tcaagcatta
      661 gggattactg acggttttta ttcaaaaggt gagaaaatcg ggggattgga agagttgaaa
      721 cataaaacgg ctatttataa taaatctgtt attgcagctg gtggagacta acctatctga
      781 cacaaaaaac tacgactttc acaaaatctg atccagatcg atatctgctt caggttgtat
      841 tatgtaagtc gtagttcttt tcttttattt agttaagagg tggtctgtcc attccctcgc
      901 ttgctcgatt tcgtccatcg tcaactgatg acctgttaca gttagctgaa tagtcacatt
      961 tgcttggcgt gtttcgaatt gatcggccaa ttctttaaag gaagcagggg aaacgattgg
     1021 atcgttatca ccataagaaa tccagacggt tttatcctct aatgtggaac ggctttgatg
     1081 aacacctaga gacatcggat ggaaaaacaa ccctttattt agctcggtct cacgctccaa
     1141 taataaatga gcagcgatgt ttgcgccatt tgaatagccg acaagcagcc aatcacttaa
     1201 cggtatcagt tctttttcgc tgatttcttt gattttttca tggagtttat ctgtttcttt
     1261 ttccaaactg tccaggtcga attgattcaa tccattacgc ttgaaaaaac gattcatccc
     1321 atcttcttgg accgtgccac gaaaagaaag caatgtactg tttggtgcaa gaaagtgagc
     1381 gatatccagt aaagaatgtt catcgccacc tgtgccatga agtaagatca aatgcttgcc
     1441 acttgttcct ttttcaaaaa tgtaggtcat tttgttccct cttttctgtt tctatagatg
     1501 caaaaaatga agtagcatga agagattatt cacgtttttt atttgcatca cttgtatcga
     1561 aaggacggac ataggcttca atggcttcac gacgttcttc taagaatgga ggaagagata
     1621 gtttttctcc tgctgattct gctggttcat cttcaaggaa tccaggacaa tcagttgcta
     1681 attcaaacag tacgtgatga gcggctagga agtactcaga ttggaaatag aaacgatcga
     1741 cgaaaccaga atttggcaat tcaatcttat tgattacttg aatccagtat tccaatgctt
     1801 ctttgtctgc tacacgcaat gctaagtgat ggatatttcc aaatccttcg attgcttttg
     1861 gcaagtctgt ccgatgttca ataatgatgc ttgcaccatt tccgccttca ccgatttcaa
     1921 ataagtagaa atctcctgaa tggtctgttt ctttgaatcc taagattttt tcaagaatca
     1981 agcggatatg ctctaattga ctgacacgga caaagacagg tccaagtcct gtgatcgcaa
     2041 actctgtcgg tacattgctg tttttccaag gaatgccagc tgctacacct tgattgtttt
     2101 cgtcagagat caattgataa tactgattat cgaaatcttc aaattcgata tattttttgc
     2161 cgaaacgttc attgattgct gaatgagtaa cgtcatattt ttcaaaacgt tccaaccaaa
     2221 agtctaatgc tgcgtcactt ggcacacgga aagaagcacg agagatcgta tctgttcctt
     2281 tttttccttt tggctgattt ggaaaatcaa agaaagtcat atctgttcct ggcgcaccag
     2341 tatcgtctgt aaagtaaaga tggtaagttt cgatgtcatc ttggttaact gtttttttga
     2401 ttaagcgcat tcctaaaata tctgtaaaaa agcggtagat ttttgtagcg ctagatgtca
     2461 ttgctgtgac gtggtgaatt cctctgattt gtgtatccat gataaatttc ctcctgtcaa
     2521 cttacaaaaa gtaagtagtt gatttagaca tagtatagag ggtgcatctc tattttgcaa
     2581 ttaatttgtc ttctaaagta tcaggaagga atcaagaatg gaaaagagga gggacggatc
     2641 aataaaataa aaagacttac gactagctgt atcgatttca aaaaaactag ctttaaaaag
     2701 ctaactttag aatcattacg ggtggtcata agtcttttta tgctgagtta ttttttcatt
     2761 tttgagctaa tgcttaggat aggatagaat gttgatttca cgatctcttc ttgttacttg
     2821 aaactgctta ctactgtcac gatctcttgg taaacggctt tttcacaacc tcttcattta
     2881 agttgaacgc acatccagca cagaatagtt ccgaacatca aatcggtttc ggctggaaga
     2941 atattcaatc ggctgtccat ctttgagata gacgacttgc tgaacttcca gtacaggatc
     3001 gttttctgca cagttcaaat attgctgatc atattcatca cttttatctg cagaaatagc
     3061 acgataagcc cctgcaaaat ggacattcaa ttcttgatga agatgatcat agatagaggc
     3121 taacaaatgt tcttttttta aacccggcac aagatggact ggcataaaag tatgctctaa
     3181 aacatatggc tcgccatcta agatccttaa ccggtgaata ttgtagacag gttgctcggc
     3241 atcgatcatc aatcgttctt ggatatattg attagggaat tcaacatcaa aatgaatgat
     3301 ttgactcttc aaagaacgat gtctgcgttt catttggaga ctcaaacctt catactcgtt
     3361 agcgggcgat gtgtcttttt gcataaatgg atgattcaag attttcgttc ctgatcctcg
     3421 ctgcgaatag acaagtcctt ccattgctaa gatattgatg gcttttttga ttgtcatccg
     3481 gctcgcacca aattctttga ccaagtccac ttgattaggc aaaaaactat cgggaggata
     3541 ctcttttgaa cggatacgtt ctcttaaaat atttgcgatt tcttcgtatt ttggcacgtt
     3601 attcacctct tctagagtat aacgaaagat tatgcttccg acaactcgaa gtagcatctg
     3661 gaacattgtt tattcgaaaa aagaggtcgt gacaagtttt tgtcacaacc ccttaatgat
     3721 ctattaagca atatctaaat ctggttgttt atctagtact ttcaggaatg ggtaccagat
     3781 aaaggcaacg atgacaaagt cgatgacttg cagcatacca ccaagccatg aatttgttgc
     3841 taagacaccg cttgcaatga ttggcacagt ccatggaaca gagacgccag ttggtgcagg
     3901 gacaagtcca gcagccatta ccaaataatt gaacgtcgtt acgattagag gtgccacaac
     3961 ccaaggaata aggattgttg cattcaatac gatcggtaga ccgaagatcg ctggttcatt
     4021 tacattgaaa ataccaggtg ctaaagctaa tcgtccaaca tcacgatact gtttcttttt
     4081 aagaacaaag gccatcaata aaacgacagc taaagtcatt ccagagccac caataccaac
     4141 agtgaaggtt tccatgaatg gttttgtgat gatgtgtggt aattcttttc catgttgata
     4201 agcttctaag ttatcaagca tcagtgtatt ccaaatcggg tccattacag agttgacgat
     4261 gatttgtccg tgaagtccga agaaccataa gaattggaca aagaacaaag caatcaatgt
     4321 tgcaggtaaa ctacttccca aaccagttaa tggtttttgg atcacttcat aaacgacgtc
     4381 atgtaagtta gcattgaaaa taccagtcat cacagcattg attactaaga aaatagttag
     4441 tgtcactaca gcagggatca aagcggcaaa tgattttgtt actgcaggcg gaactccatc
     4501 aggcattttg atctgccagc cgcgtttcgt gattctgcag tagatttctc cagccaagaa
     4561 agcagcgatc attccaatga acattccttt tgcgccaaga cgatcaagtg aaagcacacc
     4621 agtcacatct tcaccgccag cggttttcat tgcaaaaggc gtaagaatca agaagctggc
     4681 aaaagacacg gcaccaccga aaataccttc aacgtcataa gattttgata aataatagcc
     4741 gataccaaaa gtaacaaaaa ccgacatgat gctcattgtt gcattttgcc cattaccgaa
     4801 taagttcgat aaagttccct ttgttgcgtc actgaaaaaa ggcaagttat tgataacgac
     4861 aacgatcgaa ccgaacatcg ttaaagggaa ggaaagcatg aaagcatccc gcagcactgt
     4921 aaggtaacga ttttgcccta ataaattagc taagggcatg attttctcag aaagcttgtc
     4981 cataaaaccg ttcattttta ttcacctcaa atttatttgc aatcgattac atacaaagta
     5041 taacgccaaa aattttaaat gtctagtcat tttcataaaa agtattgatt tattttttag
     5101 ggttcgttat gattacgata tcaagaaaaa agagaggaag taaaaaaatg aaaacctaca
     5161 cattcccaga aaatttttgg tggggttctg ctgctagcgg accgcaaaca gaaggaagag
     5221 taagtgatga tggtaaagga gaaaatattt ggaatcattg gtatgaatta gagcctgaaa
     5281 aattcttcga tcaagtagga cctgaaaaaa cttcgcaagt ttacacaaaa tacaaagaag
     5341 atgttcagtt aatgaaagaa actggccata acacatttcg tacatctatc caatggagtc
     5401 gtttgattcc agaagggaca ggtgaaatca atcaaaaagc tgtttctttt tatcgagatt
     5461 attttactga attgctggat aatggtatcg aaccttttgt gaacctttac catttcgata
     5521 tgccactacc actgcaagaa aaaggcgggt ggttatcaag agaaacggtc gacgcttatg
     5581 tttcttatgc agcagcgtgc tttgaactgt ttggagatct ggtcaaaaaa tggtttactc
     5641 ataatgaacc aatcgtacct gtagaaggag gctacttgta tcaattccac tatccaaatc
     5701 atatcaatat gaaagaagcg gtccaagtag gctatcatga gaatctagca agcgcaaagg
     5761 caatcaaagc ctaccatgaa ggcggacatg atggtgagat cggaatcatc ttgaatctga
     5821 caccaagcta tccgagagat gaaacgaacc cagaagatgt aaaagcggcg aagatcgctg
     5881 acgcattctt caaccgatca ttccttgacc ctgcagtgaa aggagagttt ccacaagagt
     5941 tgatcgaaat tgtcaaagaa ttggctataa tgccagagat ccatgaagga gacctagaac
     6001 tcatccgtga aaacacgatt gacctgctag gaatcaatta ctatcagcct cgtcgaatca
     6061 aagcaaaaga aactccaatc aatcacgaac atagccccat gccagatgat tattttgata
     6121 attacgacat gcccaataaa aaaatgaatc catatcgtgg atgggaaatt tacgaaaaag
     6181 gaatctatga tattttaacg aatacaagag aaaactatgg taatatcaaa tgctatattt
     6241 ctgaaaatgg gatgggggtc gaaggagaag aacgatttgt taacagcgaa ggaactattg
     6301 aagatgatta ccggattgag tttgttacgg atcatttgaa atacgtccat caagcaatcc
     6361 aagaaggaac caattgtgtg ggttaccaca tgtggacatg tatggacaac tggtcttgga
     6421 caaatgctta taagaatcgc tatggcttta tcgctgttga tttggcacaa gacggtaaac
     6481 ggacgatcaa aaaatcaggt cgctggttta aaacggtctc tgaaaaaaac ggatttgatg
     6541 cctgatattt tttgataaaa cgttcacaaa atgtttgttc taacactgta atcgtgctac
     6601 actaacagtg aaggaggcgt ttacaatggt agatacttat cgtaatattt tagtagcaat
     6661 tgatggttct gaaaaggcag aaaaagcatt tcttgaggca atcacgattg ccaaacgaaa
     6721 tcaggcaacg ttgcacatcc tgtatgtcaa tgaagtaaca ggcaattact ttggtgattt
     6781 tgcatttgtt acaacaagcc ttcaggaaga attggatgag gttgcggaaa accagatgaa
     6841 agaacatcga aacttggcaa ttgaaaaagg cttgacagat atcgagacat atgttcttta
     6901 cggttatcca aagacactga ttgctaattt ccatgaatcg aaagaaccaa tcgatctgat
     6961 tgtcatgggg gcgacaggtc tgaatgcggt agaacgtgca ctagtaggtt ccactacttc
     7021 ctatgtagtc aaccacgcat catgtaacgt catggttgta aaataaataa attaagggaa
     7081 cagaaagcaa aaaagcataa cgcttctttt gctttctgtt cctttaattt tttgtaaaaa
     7141 attactttac ctgatgaagt aatcatgcta ttctaattac aacgacagat ggagtaatat
     7201 ggaggaaaga aaatgatttc aagtgatgga atacgcggat acaatgatgc gattatttta
     7261 tcgatcctta acaaaaacga ttcttatgga tatgaaattt ctaaaacgat tcgtgagagg
     7321 acaaatgatt cctatgtgat caaagagaca acactttact ccgtttttgc ccgtttagaa
     7381 aagaatcaac tgattgtttc gtatcctgga gaagtgactc atggaaaaaa gcggacatat
     7441 tataaaatca ctgaaatagg gcgtaatctt ttagaagaaa aaaagcaaga gtggctgacg
     7501 acgaaagacg tagtcgatca atttttggag ggaaattaaa tggatacaat ccgtaattat
     7561 ttagacagtc tttttatcgg agtacctcaa agtaccgaga tagataagct gaaaactgat
     7621 ttgttggcaa atatggaaga ccattatcat gaattgatgg gagaaggaaa aaatgaacag
     7681 gaggccatcg gtacagtaat ttcgacattt ggttcaatcg atgaattatt agaagaacta
     7741 gatgtcgaaa aaaaacatca agctgacgag acggaaacaa acacagcttc tatttattta
     7801 agcgaagcag aaaactactg gaaagaatac agagcggcaa gtctccaagt ggcatcaggt
     7861 gttctattca ttagcttatc ttttgcaagt tttcttttct tttgttcagc agggtatgtg
     7921 ttcatgggta tttcttgtct gattttcggt atagcattag ctgtcggttt ttttattgct
     7981 tctggtatga aaatcacacg tttaaatcac tttttgcacc atcggaaaat acctgaaaaa
     8041 gtattagcag aagcaaaaga aaaagaagaa gagtatcagc gaagttttgg cttctcactg
     8101 attgcaggaa ttggattatg tattttttca cttttcccac ttttggcttc tttaatgtgg
     8161 tatatggatg gtagtatcgg tgcctctata ttttttgtta cggtaggaac gggagtcttc
     8221 ttgatcattt atggcagtct ggtccgtcat tcttatcgtc aattcactca aagtgcttat
     8281 tactggtgaa tgtattcaga tttgtaaaaa tattttattt attgcttacc catgtaaaat
     8341 cgttatagac agatttcagt tgacttctgc gccattgtac agggataaaa agacgcatac
     8401 tatcttcatt gaatccgact aataatttct ttccgtcagt aatgatggga cgttgtaaca
     8461 aagtaaaatg cgagacgatc agatcgacaa gctctgaggt cgtacattgg tcgatttgat
     8521 ctttcaaatt tttataatca atcgagcgtt tagctaatag atcgtcaaat ccgttttctg
     8581 ttaatgacaa taaataaaat atctctttcc ttgttaaagg ctgtttaggt gtgaaaattc
     8641 gttctctgta aggcatttga tggtctttca gccagtttgc catcagatgg taactatgtg
     8701 tgcgagaaga atagatcgta agcataaaaa aactccttaa atagtccatt aatttgttag
     8761 atctgttgag ataaataata ggtaaggagc tgtgcataag cattgatcaa aacaacccaa
     8821 acatcattag aaataacttt ctaaagtctt aaacttgcga cgagaaacaa ctagactaat
     8881 agaaaaaatg tcttagccat ttggcttcct gtttgttttt ttgcttatgc tgcagctcct
     8941 cgggaaaggg ttctaacaat ttgaagaagg ttgatgattg atctagttta aattgtgtga
     9001 aatttgaaat ctggtgtttt tactagatga atcacctaac aactatgatt ataacttata
     9061 gaacttctgt tttgtacttg gttttgttat agttgttata aagttttatt ttattacaga
     9121 acatttttaa tt
//
LOCUS       DAFKHN010000096         9001 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFKHN010000096 DAFKHN010000000
VERSION     DAFKHN010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.096"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(69..1208)
                     /locus_tag="LY912_002456"
     CDS             complement(69..1208)
                     /locus_tag="LY912_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBM6956105.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1607..2905)
                     /gene="eno"
                     /locus_tag="LY912_002457"
     CDS             complement(1607..2905)
                     /gene="eno"
                     /locus_tag="LY912_002457"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBM6956106.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(3021..3776)
                     /locus_tag="LY912_002458"
     CDS             complement(3021..3776)
                     /locus_tag="LY912_002458"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBM6956107.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3880..5070)
                     /locus_tag="LY912_002459"
     CDS             complement(3880..5070)
                     /locus_tag="LY912_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBM6956108.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5180..6181)
                     /gene="gap"
                     /locus_tag="LY912_002460"
     CDS             complement(5180..6181)
                     /gene="gap"
                     /locus_tag="LY912_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBM6956109.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6222..7313)
                     /locus_tag="LY912_002461"
     CDS             complement(6222..7313)
                     /locus_tag="LY912_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBM6956110.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7462..8796)
                     /gene="rpoN"
                     /locus_tag="LY912_002462"
     CDS             complement(7462..8796)
                     /gene="rpoN"
                     /locus_tag="LY912_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBM6956111.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8856..8927
                     /locus_tag="LY912_002463"
     tRNA            8856..8927
                     /locus_tag="LY912_002463"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8889..8891,aa:Arg,seq:ccg)
BASE COUNT         2336 a         1905 c         1658 g         3102 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtttatta
       61 aaaaaatctt acgctaagta ggataaaata attccttgat atttttcgat catatccaaa
      121 taattatcga tttcaacata ctcatctact tgatgaggca aagtaacgac accaggccca
      181 aagacgacaa agtcgaagga atggttagct ttcgtaaatt cggctgcatc cgttgttgct
      241 gccgctccaa ctaaaggtaa tggctggctg aattgttgct gaatgcaatg aatcaaagga
      301 gaatctggat cagctttgac aggtattttg ttgtaatcga tcatcaattc caaatgatag
      361 tctgtctctt gattcaattc attgacgatt gattgcagca atgcaatgat tttatcattt
      421 gggtattctg gaatcgatcg aatgttccct tggagctgcg catggcttgg gatgctgttg
      481 acttgattcc cgccactgat caatgtaaca ttatggattg tttttcctag gacaggattc
      541 tcgattgttt cagcgaggtg attcatttca gcatttgctt tcgtaatgaa ttcatttagg
      601 tgattgattg cattataacc ttggtctggc atagagctat gcgcttcttt tccgtgcgag
      661 gtgactgtat agttgattga tcccatgtgc gtatacatca aactgtaatt ggttggctct
      721 ccgatgatca aggcatctaa gtcatctaca tagcctgctt tcgtgagctg ttccccacct
      781 agttcaccca cttcttctcc gacagtggct aataatttga ctgttccgtt aaatggtttt
      841 cctgactctt tcagttcgat catggcaatc accattgctg ccaagccact cttcatatct
      901 gtagcaccac gtccgtacaa acggttccca tggatttctg ctgcaaaggg tgcataggtc
      961 caagacgatt catcaccagc cgccacgaca tccatatgcc cagataggcc taacactttt
     1021 cctgattggc ccttttggta acgagcaatc aaattatctc taccatctct gtaagaaaca
     1081 atctctcctg ttatgtcatg ctttgccaaa agcttattca aataggctgc tacttcacct
     1141 tcgtttccat tcactgattt aattcggata atctcttgta aaatcgcgat tttttcttct
     1201 tttttcatct aatcctctcc cttgccattt ctttttattg tatttgagtg tgctcgaatt
     1261 ttcaaatagg agcaaccaaa gtaaaaatga agaaagagag ccactttatg aaaaatatgc
     1321 tgctacttcc ctcctatttt atttatacga gaggacttgc ccatagattc ctattctact
     1381 gttctatcct taaaagctct tatatgatgc tagttattgt tagctttcct ttttcaagga
     1441 tgatcttttc ttgtaccatt ctttgtaaac atcatataca gaagctagtt gcaaaaaaac
     1501 tctctacctg ctgatatttc agcaagtaga gagttcgatt acttaactaa gtgatcatac
     1561 tcgactatct ttcaatagtc gatcatgtat cttcattaga aaagaattat ttgtttttta
     1621 agttgtagaa agatttcaaa cctttgtatt ctgcaacttc accaagttgg tcttcgatac
     1681 gtagtaattg gttgtattta gcaatacggt cagtacgtga tagagaacca gttttgattt
     1741 ggccagcgtt tgttgcaaca gcgatatcag agattgttga atcttctgtt tcaccagaac
     1801 ggtgagatac aactgctgtg tagccagctt ctttagccat ttcgatagct tcgaaagttt
     1861 ctgttaatgt accgatttgg ttcactttga taaggattga gttagcaatt cctttttcga
     1921 taccttcaga taatttttga gtgtttgtta cgaacaagtc gtcaccaact aattgaactt
     1981 tgtcgcctaa tacgtcagtt aatttcttga atccgtccca gtcgttttcg tctaatccat
     2041 cttcgattga gatgattgga tatttagaaa ctaattcttc gtagaatttg atcatttcgt
     2101 cagttgtttt ttcgccttcg cctgagtcag ctagtacgta aacacctttt tctttgtcgt
     2161 agaattctga agaagcagca tccatagcaa gaacaacgtc tttaccaggt acatagccag
     2221 ctttttcgat tgcttcgatg attacttcaa aaccttcttc gtttgaacca aggtttggag
     2281 caaatccacc ttcgtcacca acagaagttg ctaatccgcg agctttcaag attgaagcta
     2341 atgcgtggaa tacttcagca cccatacgta gagcttcttt gaatgttgga gcgccaacag
     2401 gcatgatcat gaattcttgg aagtcgattg agttatcagc atgtgatccg ccgttgatga
     2461 tgttcatcat tggtgttggc aatacttttg tgttgaatcc gcctaggtag tggtataaag
     2521 gtacttctag gtagtcagca gctgcacgtg caacagcgat agaaacacct aaaatagcgt
     2581 tcgcacctaa tttacctttg ttaggagttc cgtctaaagc gatcatagct ttgtcgatag
     2641 ccatttggtc acgaacatcg tagccaatga ttgcttcagc aatgatgttg tttacgttgt
     2701 cgacagcttt agttacacct ttaccgccat aacgagcttt gtctccgtca cgtaattcaa
     2761 ctgcttcgta ttcaccagtt gaagcacctg aaggaaccat tccgcggcca aaagctccgc
     2821 tttctgtgta tacttctact tcgattgttg ggttaccacg tgagtctaag atctcgcgag
     2881 cgtaaacatc agtaataatt gacatgtttt gtctctcctt tgagtttgtt ttttcctaag
     2941 ggatttccct catatacgat tttagttaat tttgctcatt agtgcaaaca tttcttgcat
     3001 ttttcgcaaa ttttcaacaa ttattttaca gcgtctaaca atgacaagaa tgaatctgct
     3061 tgcaagcttg cgccaccgac taaagcaccg tcaacatttt cttttgccat gtattcagca
     3121 atattttctg gttttacaga accgccgtat tggatacgaa ctgcttctga tacttctttt
     3181 ccataaagtt tttcaactgt ttgacgtaca actccacaaa tttcgtcagc gatttgtgcg
     3241 tcagctgatt taccagtacc gattgcccag attggttcat aagcaataac catgtttgac
     3301 acctgttcag ctgaaagatc agctaaacca gctgtaattt gtccttcgat ccattcagca
     3361 gttttgcctg cttcataggt ttctaaagat tcgccgcagc ataggattgg tgtcatacca
     3421 tttgcaaaga tagctttcgc ttttttattg atgtcttcgt ctgtttcatg gaaatattca
     3481 cgacgttctg aatgtccgat gatcacataa tgaacaccta gatcagcaag agctgctggt
     3541 gaagtttcac cagtgaacgc acctgagttt tcccagtagc agttttgtgc tgagattttt
     3601 agttctgtac cttcagctga tgtcattaat tcttgtaaga ataatgcagg agatccgatg
     3661 actgaatcaa ctttgtcatt tgaagggatt ttgtttttta ctgcttcagc aaattctttt
     3721 gcttctgatg cagttttgtt cattttccag ttacctgcga taataggttt acgcattgag
     3781 gaacacactc cttaatttat tgaaaaatgg ctagggagtc atgaaaactc ccttcacctt
     3841 ttgttcgatt actcgtcaga attgagcaaa cttggtcgtt tatttatcgt tgattgctgc
     3901 tagtcctggt aattctttac cttcaagcaa ttccaagctt gcgccgccac ctgttgagat
     3961 gtgtgtgaat ttgtcagcaa atcctaattg ttctgctgct gcggctgagt ctccgccacc
     4021 gatgattgtt gttgcgcctt ctaagttagc gattgcttca caaacaccga ttgtaccttt
     4081 agcaaagtta ctcatttcaa atacacccat aggtccgttc caaacaactg tttttgcacc
     4141 ttgtaatgta tcagcaaata attttactga tgctgggccg atgtctaaag ccatcaaacc
     4201 atcaggaatg tctccttcga ttacttgtgt ttcaacatca tttgaaaatt ctggtgcaca
     4261 gacattgtcg attggcaaga caagtttgtc gcctgctttt tcgattaatt cttttgctag
     4321 ttccacttta tcagcttcta ctagagagtt accgatcttg attccttttg cttcgtagaa
     4381 tgtgtaagtc attccgccac cgatcaagat tttatctgct ttaggaatca agttttcgat
     4441 tacgccgatt ttatcagaaa cttttgcgcc accaaggatt gcaatcattg gtcgttttgg
     4501 ttcttctact gcttcaccga tgaacttgat ttctttttcc atcaagaatc cagcaactgt
     4561 tgggatacca gttgaagcga tacctacgtt agaagcatgt gcacggtgag ctgtaccgaa
     4621 agcatcgtta acaaatacat cgcctaatga agcccagtat ttacctagtt ctgtatcatt
     4681 tttgctttct tttttaccgt caatatcttc aaatcgtgta ttttcgaata cgacaacgtc
     4741 gccgtcattc atgttgcgga ttgcttcttc taattgttct ccgcgagttt caggtacgaa
     4801 tgttacttct ttacctaata attcgcctag acgttttgca actggagcta aagattttcc
     4861 ttctttatct tcttctgttt ttacacgtcc aaggtgagag aaaaggattg cttttccgcc
     4921 ttgttctaga acgtagttga ttgttggcaa tgctgctttg atacgagtgt cgtcagtgat
     4981 cacgccgtct ttcaaaggaa cgttgaagtc aacacggaca agaacttttt tgtcttttaa
     5041 atcgatatct ttcactgttt tcttagccat tttatttcct cctgaataaa cttattatca
     5101 aaaaaagcgg aagaagcgcg attgcttccc cgcttttaaa tgtacatgtc tataatttac
     5161 acttgtacgt ttgtctatct tataagttag cgaagtattc taaagtacgt actaattgtg
     5221 cagtgtatga catttcgttg tcgtaccaag caacagtttt aactaattgt ttgtcgccaa
     5281 ctgtcattac tttagtttgt gtagcatcaa ataatgaacc gtaagtcata ccaacgatat
     5341 ctgaagaaac gatttcgtct gtgttgtatc cgtaagattc gtttgaagct tctttcattg
     5401 ctgcattgat ttcgtcaaca gttacttctt tttcaagaac tgttactaat tctgttaatg
     5461 aacctgttgg tacaggaaca cgttgagcag ctccgtctaa tttaccgttc aattcgggaa
     5521 ttactaaacc gatagcttta gcagcacctg ttgagttagg aacgatgttt gcagcagcag
     5581 cgcgtgcacg gcggaagtca cctttaggat gaggtccgtc tagagtcatt tggtcacctg
     5641 tgtaagcgtg gatagttgtc attaatcctt caacaacacc aaatttgtcg ttcaatgttt
     5701 tagccatagg agctaaacag ttagtagtac atgaagcacc tgagataact gtttctttac
     5761 cagttaatgt ttcgtggttt gtgttataaa cgattgttgg aacatcgttt ccgccaggag
     5821 cagagataac aacgcgttta gcaccagctg ttaaatgttt ttcagctgct gatttagaag
     5881 tgaagaaacc agtacattct agaacgatat ctacgcctag ttcgccccat ggtaattctt
     5941 ctgggttgcg gttagctaat actttaactt cttttccgtt tacgttgaat gaaccttcat
     6001 gaacttcaac tgttccgttg aaacgtcctt gagttgtgtc gtattttaac aagtgtgcca
     6061 acattttagc atctgtcaag tcgttgattg ctactacttc gattccatct acatcttgga
     6121 tacgacggaa tgctagacgt ccaatacgtc caaaaccatt aatacctact ttaactgtca
     6181 tttaagattt cctccttatg aaaatcaaaa aaatatttat tttaaagggt tacccctttt
     6241 aaaatctcat ttgcagcagc ttcatcagtg atgagccacg tttgttttgg tgcatttttc
     6301 atataagctc gaattgcttt agcttttgat tttccgcccg cgattgccat gatgatcggg
     6361 actttttcca aatcttgcaa ttctatgccg attctaggga ccttataaac gacttcacct
     6421 ttttcattga aaaagtagcc aaaagattcc gcaacagcat ttgcttgttt cagcatgact
     6481 aattcttttt cagtcatctt acgacgtgct gccatgtgta atgcacgccc aatactatga
     6541 ataacacaat tcgcttcact aatcaagttt aagacttctt ggatagatgg ctcattgagt
     6601 aaagaattgt aagttgccag acttaattgt tccggaacat aaagtgcgcg gtggttaccg
     6661 tttgctttag cagccattct tgcactgaca gaatttgcct gtacagttat cgcttcacca
     6721 atcccgcctc ttgcagggac aaacaggtta tgccgtttct tattttccag attagacaat
     6781 tgttcggcta ccacagccat agtagttcct cccatcacag cgatgatatt ctcgccttct
     6841 ggaagtagtc ggtctaaggc ttcgctcagc gcttcgccga atgcatcagc cactttggtc
     6901 tgctcttcgc tgtttcctga aacaacgata cagcgttggt taccaaaata ttctgccaac
     6961 tgttgttcgg tttgatgcgt acctaaaagc tgatccatga agttttcaag gctttgataa
     7021 acttcttcgc ccttagttgt cagcgtcata ccgctttttg aggtgtcgat caaattcaga
     7081 tttttcaaaa ggtctgtttc tgttcgtaag actcgttctg tgatccccat actttccgat
     7141 aaacttcgac gcccaatcgg ctgcatccaa tagatatttc gtaaaatttt atagcgttct
     7201 tgcaacactt cgataatatc tggtgcaaca gattcaatca tttttatttc atccagcata
     7261 gcgatctcct tagttggaca ctttacgtcc aatgtagact taaaacgacc catatacgat
     7321 aaaaaaagaa attaactatt cgaatttcac atcaataaag ggaaatctca acctcacgac
     7381 tgtaagtcta acagttttgc tctcgttttt caactaaaaa gactagaaaa agtgaaatac
     7441 tttttctagt cttttgactg attagttatc ataacgtttt ctttttgatg aactcgggat
     7501 tcctaataaa tcacgatatt ttgctactgt tcgtcttgag atcgctatct catctttttt
     7561 cagcaattca accaatttct ggtcagacaa cggcttgttt ttgtcttctt gatcgactaa
     7621 ttcctgcagc tttttcttcg ctgtatctgc tgaaaggtct tctgtctgtt ctgtactatt
     7681 cgtaggaatt cgtgtagtga aaaatttttt taattcaaat acaccgaagt ctgtttccaa
     7741 atatttcccg ttgactgcac gactgaccgt ggattcatgc acatctatct cagttgcaac
     7801 ttcctttaac gtaagaggct tgattggacg ttccttgtcg ataaagaaag ctttttgccg
     7861 ggaaacaatg acttgagcaa cccgcaaaat tgtatcccca cgttgtagga tcgttttctt
     7921 caaccattcg aattcctgtt tccgttcttt taaataattt tcagtttctt tatctgcttg
     7981 ttgtgacatt tgtttgaagt aactctcttg aaagcgtata tttggctgat tttttcggtt
     8041 tgagataact tgtacatttt tatcgtcgtc cactaatacc cggacatcag gaataatgta
     8101 caattcgctg ctacggtcga aaatccggcc agggcttgga ctcaacgttt gtaaatagtc
     8161 gaatatctgc tgaacagcat gtagatcaac agaaaaacgt tgtgcgattt ctttccattt
     8221 tcgctccacc agttcctcaa aacattcttc caacacgata taagctaatt ccggcgcata
     8281 atcatctcgt tctgtttgaa gcatgagaca ttcttgcaaa ctacgtgcac ctactccagc
     8341 tggttctaat tgctgaatca gagtcaacgc atcgagcatt tggataggcg tagctccaat
     8401 ctcttttccg gcttcttcta aactaatcgt caaaaatccg ttcaaatcga tgtattctac
     8461 aagataaaga acgattttcc tcaaaaaagt atctcggtaa ttcaaatgga cttgttcgat
     8521 caatgaatca aataaagacc cttttgtatc aggaatctga tttaggtaat ttgtctcttc
     8581 tccttcataa gaagatgaag aagcttttat gtaatctggc tgccattccg gctcaacaac
     8641 ttccaccaat ggattttcca ttgcttgatt ctcaacgaat gccaacagct cctcactgtt
     8701 atattgtaaa acttggatgg actgttgcaa ctgttgcgtc atggctagtt tctgtgtctg
     8761 ctgctgtttt tgtgaaaaat tttgctcaaa tttcattttt ttgtccaatc cccttgtaat
     8821 tttttatctg tttagttaca attatcccag tgcttgcgtc cttagtgtag tggatatcac
     8881 gtaagattcc ggttcttgag acgggggttc gattccctca ggacgcgttc tactgctatt
     8941 ttagcataat ttacgaatag ttgcttcttt atttttaagt gaaaactgtc cgccaaagaa
     9001 a
//
LOCUS       DAFKHN010000097         8942 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFKHN010000097 DAFKHN010000000
VERSION     DAFKHN010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.097"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            51..260
                     /locus_tag="LY912_002464"
     CDS             51..260
                     /locus_tag="LY912_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956112.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="LY912_002465"
                     /pseudo
     CDS             467..667
                     /locus_tag="LY912_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="LY912_002466"
     CDS             complement(1379..1984)
                     /locus_tag="LY912_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956113.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2166..2501
                     /locus_tag="LY912_002467"
                     /pseudo
     CDS             2166..2501
                     /locus_tag="LY912_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2666..2893
                     /locus_tag="LY912_002468"
                     /pseudo
     CDS             2666..2893
                     /locus_tag="LY912_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3019..3990
                     /locus_tag="LY912_002469"
     CDS             3019..3990
                     /locus_tag="LY912_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6956114.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4130..5443
                     /locus_tag="LY912_002470"
     CDS             4130..5443
                     /locus_tag="LY912_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBM6956115.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5486..6352
                     /locus_tag="LY912_002471"
     CDS             5486..6352
                     /locus_tag="LY912_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6956116.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6349..7197
                     /locus_tag="LY912_002472"
     CDS             6349..7197
                     /locus_tag="LY912_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6956117.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7211..8683
                     /locus_tag="LY912_002473"
     CDS             7211..8683
                     /locus_tag="LY912_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBM6956118.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8700..>8942
                     /locus_tag="LY912_002474"
     CDS             8700..>8942
                     /locus_tag="LY912_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBM6956119.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         2830 a         1515 c         1831 g         2766 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttta
     2041 ctgttatcat agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt
     2101 tttgaatgaa tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta
     2161 gctcggaaca gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg
     2221 gtagaaaagg caaactttat caaacttatt acgacggtat ggaggaacag ctcaacgcat
     2281 taggattagt aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg
     2341 aacaaattaa aacggaaggg ttcgactgtt ccgaagaagt gttacgcaag caatttccat
     2401 taattagtga tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat
     2461 cgaatggaat actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt
     2521 cctaccgtgc attttcgcac ggatgttcca gatactattt ttgaatgtat aaaattgaaa
     2581 acacaagaat actaataaat caacgattct tgtgttttta atttttcact accgtgcatt
     2641 ttcgtttcta tgttccatgt accccaatct tgaaaaatta attaaagact tagataaagc
     2701 cattgacgac ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat
     2761 tggtcctgtt taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga
     2821 tgaaataaaa ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc
     2881 tgaatacgaa aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat
     2941 attcctgcta atttggaatc gtttccttct tttggtataa taatacctga aattcttttg
     3001 agaggagttg ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt
     3061 ggtgtgggta cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa
     3121 aaagtaatgg ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg
     3181 aaaacgaata gtagcaatac aatagctctt attttaccta cgatttggca tcccttcttt
     3241 tccgagtttg cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg
     3301 tgtaatgcga acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt
     3361 aaagtagacg gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat
     3421 ttaccatttg tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat
     3481 aattatttag gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg
     3541 tgctatgttg ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt
     3601 tacaatattt gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt
     3661 agcaatttag aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt
     3721 tttaccatca atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag
     3781 gaagcaccta aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa
     3841 gactatttac tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa
     3901 acactcatgg cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc
     3961 tttcacgctg gagagacgac taaagagtaa aaaaccggtt tataacgatt tttttgagat
     4021 aggttgacag aaagtgattt caatgatatc ttaaaaccaa ttaattggaa acgttaccaa
     4081 ttaattgaaa aataaaacgg aaacgtttca aaaaatagga ggaacatcga tgaaaaagag
     4141 aatgttagca attgcagcaa ttttagcatt aacagctgga ggacttgcag gatgtggcag
     4201 taaggagaaa agttcaggta gcagtgatcc aggagaaatt aagatttggg ttcagttttc
     4261 tgatgaaacg cctgaaggaa aagcttgggc agagattgtg aacaatttta atgatgaata
     4321 cgagggtgaa tataaagctg ttactgagta tattcctcgt agcggaagcg gcggtggata
     4381 tgaggataaa gtaaatgctg caattacaac caataccctt cctgatgtta ttacgttaga
     4441 tggaccgaat actgcagctt atgctcattc aggagtcatt gctccattag atgattattt
     4501 gaaagatgcg gacatggatg atgtattaga cagcattatt cagcaaggaa cctacgatgg
     4561 caaaatgtat gcgtttggtt tctcagagtc cagtgtgggt gtctattaca ataagtcgct
     4621 gttcaaagat gctggaatta cagaagatca attgccgacg ttagaagatc cttggacttg
     4681 gacggaattt caagcaattt gccaaaagct gactgataaa tacaaaacgc ctgcaattga
     4741 tatgcaaatg gcgtcgggag acgaaatgct gacctacgca tatacaccat ttatatggtc
     4801 gaatggcggc gatgtcgtta atgctgatgg aaccaaagcc gaagactatt ttaacggtaa
     4861 aaaatccgtt gaagcgttgg aatttattca agaattggtt gaaaaaggtt acaccacaat
     4921 cagtcctatt gaaaaaggat ttgaaactgg caaatatgcc atgatgctga gcggttcttg
     4981 gacaatggca gatttagagg aaaactatca agagattgat tatggtattt tgccttaccc
     5041 cgtttcagat gcaactgggg agttagtttc accaaccgga agctggcagt tagcaatgac
     5101 tgagaaaaca gagaaaaagg atgcttctgc ggcctttatt aagtttgcaa ccagtacaga
     5161 atctagtcgt attatgagtt tagggaacag tgttctacct atcagaaatt caacagttga
     5221 tttaattaaa gatgaagtgt cggaaggaat gcaggtatta attaagcaaa accaactttc
     5281 tggacatgcc cgcccagtgg ttgtagctta tccgcaagta tctagagcat tccaacaagc
     5341 agttcaagat attagctact tcgaggaaaa cccagatgta caaaaagtag cagatagtcg
     5401 cgctgctgaa atgcaacagg caattgatac ttcactaaaa tagaagtttc taaagggggc
     5461 caatcaagtg ttaaaaaaac cgacaatgaa agacaatttg ataggttacg gctttctagc
     5521 gccagctttg ctgctgctga cgatttttct gatcataccc gtaatcatgg taatttatta
     5581 tgcctttact gattattatt tgttaacgcc agatgctaga caatttatcg gcttagaaaa
     5641 ttttaagcga ctgttcgctg atccaatttt tgtaaaaagt atttggaaca cggctaaatt
     5701 tgttgtttgg attattccgg tccaaatagg ggcagcttta ggaatggcac ttattatcaa
     5761 caaaaatcgt aaaggaaata tcttttttaa agtagccttt tttgcgccag tcgtgatgtc
     5821 cttagtcgtt atttcgattt tatggttgta cttgttaaat cctaatgaag gtctggttaa
     5881 tacgctattt gcaaagattg gaattgcttc gcagcctttt ttgactagtc ccaaacaagc
     5941 aatgtatacg cttgttttcg tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt
     6001 tttaggggga atgcaaaata ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt
     6061 ttctaagttt cagcaatttc gctatatcac catgccatta ttaaagccca cggcgatttt
     6121 tattttactt accacattga tttcggcctt taaactaatc attcagccaa tggtaatgac
     6181 tcaaggtgga ccaatgaatt ctactatgac aatggtttat tacatttacc aaactggatt
     6241 tacagaccgt atggtaggct actccagctc cattgcgtta atctttacca ctatgattgg
     6301 tttaattaca attgctcaaa gaaaattggt aaaggaggat gatccagcat gaccaagaaa
     6361 tttggaccgc taatgatcgt agaatattgt ttgctgttcc ttttagcggc attattcatt
     6421 ttcccgatgc tgtggatggt agtttcctct atgaagcctg aagcagatgt ctatcaaaat
     6481 ttagcttcct tcaaagcttt tttacctagt ttgaatccag ctaattggtt taaaacttat
     6541 caagaggtta tttcccggtt cagtgtggga acttatttat taaacagtat tttttatggt
     6601 ttaacctttg cctgtgggtc aatcattgta aactctttgg cgggttttgc ctttgcgaag
     6661 gttaattttt caggcaagaa aattatcttt ggagctttgt tagctctgct gattgtcccg
     6721 atggagacgg ttttaattcc gcaatttacc atcgttaatt cactaggctt agtgaatact
     6781 cgcttggcag tgattttacc agcgatggcc agcgcgttta atatctatct gtttagaaat
     6841 ttctttatcg cgattccaga agaaatcatt gaatcagcga aattagatgg tgcaaatatt
     6901 gttaaaattt tctttcacat catgctgcca atgtctaaac cagccatagc cacagtaggt
     6961 gtcttatcct ttatctccag ctggaatgat tatatttggc cgttaatggt cttaactgac
     7021 agcagcaaat tttcaatgca agtggcaatt actacgatca atactacaca gccagtttat
     7081 atcaatcaag tgatggctgt tttaaccatt gcaacgattc cactgattat tgtttatatc
     7141 gttgcacaaa aatatattct gcagggactt ggcggttctg gaacgggtat aaaataggag
     7201 tgaatagtga atgttgcaaa aacttttaaa ggccaatgag tttattgaga aaaatgctca
     7261 aacagtcaat caagaatacc ggaataaatt tcatttgatg gctccgattg gctggatgaa
     7321 tgatccaaat ggttttgttt attatcaaga ggagtatcac ttgttttatc aatattatcc
     7381 ttacgacagc atctggggac caatgcattg gggccatgct aaaagcaagg atctaattca
     7441 ctgggagcat ttgccagtag cactggcacc aggtgaaagc tatgacaagg aaggctgttt
     7501 ttccggcagt gccatagaaa aggatggcaa gctgtatttg atttatacag gacacaatgt
     7561 tgtggaaggg caagttcgac aagttcagtg tttggcagtt tcagaagatg gcattcactt
     7621 tgaaaaatat gccggaaatc caatcatcgc agaagatcac ttagcttctg ttgcaacgac
     7681 cgaagatttc cgcgatccca aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc
     7741 tactaaaact gcagatgctc gtggacaaat tgtgatgttc cattccaaag atttactaac
     7801 ttgggagttt tattccgtat tgctggaggg aactccagaa caaggcattg tatgggaatg
     7861 cccagacttg tttgaactag atggcaaaga agtcttgatt ctttctccta ttcaaatgac
     7921 tccacaaggc aatgcttacc aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga
     7981 ttggcaaaca ggcaaatttc tagtagagaa ttttcatgaa atcgatggcg gtttagattt
     8041 ttatgcaccc cagacctgtg aaaacgaagc aggccaaaga ataatgattg cttggatgca
     8101 aatgtggcag cgtaaaatac ctacgaatga tctgggccat ggttggtcag gttccatgac
     8161 cttgcctaga gagctgaggg tggctgataa tcaattgttg caacggccag tttcatcaat
     8221 ttatcaagta attgatccgc aggaaaggat tgaatgggcg aagactgaag agaatcgctt
     8281 cttactgaag gacttagtat atgaccagca ctatttacgc ttggaaatca atttaaaaca
     8341 ggcaacgaaa ctagaacttc actatgcgaa gggacccgac catacattac tgcttaacta
     8401 tgatgttgaa cgggagtgct ttactgcttc cagggaacac atgccgtatg atttatcagg
     8461 agctgaaaag gaagtgttga aaaagcgcag tgtgacgatt cctttggaaa ataattgtct
     8521 aaccatcgaa attttccgtg atacttcagc tattgagctt tttctaaatg atcgtctgac
     8581 tatgagtaca actttttatg agacagaaaa aggacaggat tttcttttgc tggcagacag
     8641 tgaagtaacc ttttcattgg aaagcggctt aattaatcta tagaagggag agctcagtga
     8701 tgatttatgg ttcaatcgaa gcaggcggca caaaatttgt gtgtgccatt agcgatgaag
     8761 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatacctt
     8821 tagtcattga cttcttcaaa caataccaag cagatttagc agggattggg attggctcat
     8881 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
     8941 aa
//
LOCUS       DAFKHN010000098         8883 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFKHN010000098 DAFKHN010000000
VERSION     DAFKHN010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.098"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(383..880)
                     /locus_tag="LY912_002475"
     CDS             complement(383..880)
                     /locus_tag="LY912_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBM6956120.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(920..1729)
                     /locus_tag="LY912_002476"
     CDS             complement(920..1729)
                     /locus_tag="LY912_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBM6956121.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2063..2920
                     /locus_tag="LY912_002477"
     CDS             2063..2920
                     /locus_tag="LY912_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBM6956122.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            2913..3815
                     /locus_tag="LY912_002478"
     CDS             2913..3815
                     /locus_tag="LY912_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBM6956123.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            3848..4198
                     /locus_tag="LY912_002479"
     CDS             3848..4198
                     /locus_tag="LY912_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBM6956124.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4247..5170
                     /locus_tag="LY912_002480"
     CDS             4247..5170
                     /locus_tag="LY912_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBM6956125.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            5248..6141
                     /locus_tag="LY912_002481"
     CDS             5248..6141
                     /locus_tag="LY912_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBM6956126.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6179..6742
                     /gene="amaP"
                     /locus_tag="LY912_002482"
     CDS             6179..6742
                     /gene="amaP"
                     /locus_tag="LY912_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBM6956127.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6756..6944
                     /locus_tag="LY912_002483"
     CDS             6756..6944
                     /locus_tag="LY912_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBM6956128.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            6957..7859
                     /locus_tag="LY912_002484"
     CDS             6957..7859
                     /locus_tag="LY912_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBM6956129.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            7891..8133
                     /locus_tag="LY912_002485"
     CDS             7891..8133
                     /locus_tag="LY912_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBM6956130.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8389..8760)
                     /locus_tag="LY912_002486"
     CDS             complement(8389..8760)
                     /locus_tag="LY912_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956131.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3095 a         1535 c         1720 g         2533 t
ORIGIN      
        1 agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaagta aaaacagctt
       61 cttatgtttt tacttggctg ttcttattac tgcagatgca agcttttgaa taccgtttaa
      121 ggaagaggtt gtgaaatcag cgttttgacc tgagtattag cttaacaaac ggaaaaatag
      181 ttcctcatat tttgccgttt gttaagctaa taccgagggt cagctgattg aacaccattt
      241 aagaaagagg tcgtgagcct gccgtttcac tctgtgtcat aaaaaagcca atctactttg
      301 atagaaaaag cacgtaggac taaaacagtt ctgcgtgctt tttttattgt gtgttaaata
      361 tcgtaaatga agatagatat ttttatgatt cgacgataga gacgttgaaa tctttcaaca
      421 gctctaaagc ggattctccg tgttttctac tggagactaa cattggatca acaaaaaagt
      481 ctgcttcagg aaaagcactc tgcaggccta tcagattaga gagtacacac aagtttgttt
      541 caatcccgac tacttcgatc tctttttgtt cttctttgct ttcaaataaa gtttcctgga
      601 tttcagctaa agtttcaggt ggaatcgtaa agtaatactt tttaatcact cgttcatttt
      661 cttgtggaga aagaagaggg atcaattgca aatcttctcg ttcttcttct ttgtccttca
      721 gttcaactgg tatatcccgt gtgaagagaa tatattcatt attttggcgt gctttagcta
      781 atctttgagc aatacgttct gccaattgat ctgactctgg aatataaaat tcgctgtttg
      841 gatcaagaat atgattttgc atatcaataa taactaacat tttctttcct cctacattca
      901 tatcgtcatt ttattctttt taatagaagt tttttaaaat ataagcaaca ccagcttctt
      961 cattcgtcag tgttacttgg tttgcaattt cttttacttg tcgctgtgca ttccccatcg
     1021 caatactcaa cccgctgtaa ttcaacatag caatgtcgtt ttcttgatcg ccaaaagcca
     1081 tgatgtcact cgattcgatt ccaaggtaat ccgccagaaa aacaagtgaa tgagctttag
     1141 tgatacctgt aggcgtgatt tctaagaaat gcggatcaga gaatactgat tggataccat
     1201 ctgcttgcag atctctttgt agcttctgta gtttttcttc actcttatct gttaatgcta
     1261 atttaagata gctaagagaa ggatcttcca acatatttaa aatttgatca aaagaatggt
     1321 tctgtaaatt gaaatgttca taataagggt catctttgac tagatttgat tcatcgaatg
     1381 tcagctgatc atcttgggtt tctcggctag caatgatgga tattttcgct tcttgagcat
     1441 agaagaaggc ttttctcagt gtatcgctat ctatttttga acgtctgaga actttcgcca
     1501 tttttccatc cttcatttca gcaatcagtg aaccattgga agaaatcaaa tagccaccga
     1561 ttcctaattc ggaaaaaata tctttagcag aaatgctgtt ccttccggta gcgacggtta
     1621 cgattccgcc attttcatca aatttccgaa gtgcttggat attttcttct ggtatctttc
     1681 catttcgatc aagcaaggta ccgtctaaat caatcgctgc tagtttcatt ttatcttcct
     1741 actttctttt tacatatcta ttttcctgtt accttaagat taaatgagaa tttaaaaaaa
     1801 tgaaactaac ttgctttgtc attatgaatt ttttcaaaaa acattcttaa gaaaaaggtg
     1861 gctatatata gtagtttttg gtcaatacct ttgaataaaa agccatgaaa aacgaatagt
     1921 tagcgcttac cgatgcgttt tgtgataaaa aaattttaaa atattcaatg aaaacaaagc
     1981 atatattttg ctttaaaacc aaatgaggaa tattctagat gtagaacagg ttagaaaaag
     2041 attagaaaaa ggagtgattt tgatggagaa gagatacggc gtagttcctg tggtaactgc
     2101 ttcagacgaa aattatgctc cttacttgag cgtgatgatc gcaactgcat tagaaaattg
     2161 caataaaaca agacgcataa aattttatgt gattgacgat ggtctatcag aatatagtaa
     2221 agaaggattg gaagaaacgg taaataaata ttcaagtaat gcaagtatcc aattcctgac
     2281 agtggaaaaa gatatctacg aagacttcct agtcagtgac catatcacaa ctaccgctta
     2341 cttaagaatt tctttaccaa acttattagc taaagaggat tataagaaag tcctttactt
     2401 agattcagat gtgttagtac tagacgatat cgtaaaacta tatgatgagc cgttaaatgg
     2461 aaaaacaatc ggcgctatta tcgatccagg ccaagtgaaa gctttggaaa gattaggaat
     2521 cgattccgat gacttgtact tcaattcagg agtgatggtg attgacattg atcaatggaa
     2581 taaaaaagaa attacagaaa aaactatcca ttacctcagt gaaaatggcg atcgaatcat
     2641 ctatcacgac caagatgctt tgaatgctgt actttatgaa gattgggaac aacttcatcc
     2701 aaaatggaac atgcagactt cgctgatttt tgaacgtcat ccagcaccaa atgaaaaata
     2761 tgaacgtcag tataaagaag gaaatgaaaa accttcgatc gttcacttta caggacatga
     2821 taaaccttgg aatacgttga aagatcatcc gtataccaat ttatacttaa aaaaattagc
     2881 acacagtact ctaacgaaag taggcgagat caatgaataa aaaagaaata gcagtagtcg
     2941 caagttgtaa cacaaaattc gtaccacatt tagctgcatt atttgtctca gtattagata
     3001 attgcaaccc gtctaaattt gttcggttct atgtgattga cgatgatatc gattttgaaa
     3061 gtaaacagct tttacgcttc tcagtgaaaa acgcacgaat gaactcagat gtggaattct
     3121 tgaaaatcaa taaagaattc tttacaaatg tggtaatcag cgatcgtatt ccagaaacag
     3181 cttattatcg tattgcgatt ccggaattgt tccgcggcac agaagttgaa cgtatcttat
     3241 atatggattg cgacatgatc gctttacaag atatctctaa attatggcgt cttgacttcg
     3301 gtgattcaat cgtagcagct gttgaagacg ctgggttcca tcaacgactg gaaaaaatga
     3361 aaatttcagc taaatcaatg cgttatttca actcaggttt gatgctgatc aatgtgaaaa
     3421 aatggttaga tgaaaatatt acgcaaaaag tattagattt catcgaacat aatccagaaa
     3481 aattacgatt ccatgaccaa gatgcattaa atgctatctt acatgaccgt tggttaccac
     3541 ttcatccgcg ttggaatgca caaggctata tcatggcaaa agcaaaaaaa catccaacag
     3601 cagcaggtga acgtgaatac gaagaaactc gcaacaatcc ttacattatc catttttcag
     3661 gacatgtgaa accgtggagc aaggattttg aagggccaac gaagaaatat tacgaaaaat
     3721 atgcagggat gacggctttc cgttgtgtag ctaaattccc taaatatcca aaatatgcaa
     3781 aagttcaacc aaaaacagat gtagttgtta aataatagaa gacaacaact gaagaggggg
     3841 agtaggaatg gaaattacaa tgtctaaaaa tgcagtagag acgttaattg aaaaggttgg
     3901 ggaaaataca aaaatcgcac tcgcgcttat caatgattcc gatccatttc taagggacaa
     3961 aggtgctttt gcaaaaggca gcttttttca aatcattcct tttgtttcgg aatttggaga
     4021 atatgcgact aaaatcgagc atccattatt ggacatctat acatctaaat tagagcaaaa
     4081 ttatttcggt aaacgattga acatggactt caacaaacag cttgacagct tttcattaga
     4141 aaatgaaatc gcagtactcg attataatat caaattaaag aactgcttct tcagctaata
     4201 gtttcgagaa agtccaaaaa ggaggtatac attgagatac tactttgtgg atgaagaaaa
     4261 gaatgtaata gaaacagatg aaaaaaaata taattggctc gtacttgata gtgcaaagcc
     4321 cgaagagatt gagcaagcaa tcgaagaatt cgagcttcct gatgatattt tcgtaggaac
     4381 cgaatatccg gaagaagttt ctcggatgga gcgcctttat gagacgaaac tagagcatcc
     4441 attttctttg gtagtgatta atctagatca gtcagataat cgtatcgaaa aaaaattaac
     4501 gccaatatct tttgtacttt ccgataatct cttgattact tgtatcgata gaaaaaccga
     4561 atttgtggat cggctgctga caaagcatgg aaatcattta aactcgtttg aaaagatcat
     4621 cacgtataca ttattagata tttacaccca ttacgtgaaa gaactaagag agatgaaaaa
     4681 gcgaattgac gctttggata aagcagctcg taaaacaacg gaaaatgaag aactgtataa
     4741 acaggcagat cttgaaagag acatcgtata tatcgatcat accttaagag atcaacggga
     4801 aacaatggat caattatgga attctgaaac tttcatcaaa cgtttagacg atgaacagct
     4861 actctatgat gtccatttga gacagcgaca aacagaaaaa atgatcgaga tctatcgaga
     4921 tttattagag agtattggtg atctattcaa cgggatgatg gacaataatc taaatcatat
     4981 catgaaatat ctagattcag ctgcattaat catttccgtt ccggcgttgt tcgcagggat
     5041 ttggggaatg aatacaggag gattaccggg taaaagttct gctctaggct ttatactcgt
     5101 agtctttggc tctttgatag cagcagtagt tttaggttac catttatacc ggaaagatta
     5161 tacaaattaa agaatctatt taaaacaggt atcaaacaaa gaaatttgtt ttggcaatac
     5221 aatttaaaaa ctaggaggaa tacagcaatg acagaaccaa aattaatcga cccgcgaaac
     5281 ttgtaccata cggagaaatt tcctaaacaa gatcaggata caccagcttt acagcagaat
     5341 atgattcctg ttcctgattg tggagaagaa tcctatgaag gcaataatca actagaaaac
     5401 cgccgtgtac taatcactgg tggagattca gggatcggtc gtgcagcagc gattgcattt
     5461 gctagagaag gggcagatat cgctcttcaa ttcttcccag gagaagaaaa agatgcagag
     5521 gaagtagcaa aatacgtgaa agttgcagga cgtaagattg tcttactacc ttttgatctt
     5581 cgtgacgaac aagcacctaa agaaatcata gataaagccg tgagtgaact tggcgggcta
     5641 gatacgatgg tactaaacgc aggacagcaa atttcttgtc agtctattgc tgagttacca
     5701 cttgagcaag tcaaagacac atttatgata aacatcatcg ctatgtttgc tttagtgaaa
     5761 gaagctgttc cgcatatccc agcaggagga gcaatcgtaa caacaacttc tgttcaagca
     5821 ttcaatccaa gcgaacattt attagattac gcagcaacaa aagcttcaat cgctaacttt
     5881 acgatcggtt tagcaaaaca gcttgcacct aaaggaatcc gtgtaaatgg tgtagcacct
     5941 ggtccaatct ggacaccatt acaactagac gaaggacaac cttctgattc gatccctgaa
     6001 tttggtcagc aaagtttact agaacgtgca ggtcagccag gagaattagc accagtttat
     6061 gttttcttag catcgaataa agcaagttat gttacagccc aaatttacgg agtaactggt
     6121 ggagaagcga tcaacttata agaagttgat cgtttcaccc ctatgaggag gtgcgaaaat
     6181 gaataaaggt gtaaaaacga tcggagtgat cggaacatta cttttgctat ctgtgctttt
     6241 gtttgcgata ctattaagtg caacctatcc attgcctttt cagctagaga agtttcgatt
     6301 cttttccatc actaattcat acgtgcaaca atatgtattt tggcttgccg ttgcatttgc
     6361 tattttgaca attatcacgt tacttgtttt cctgttttat ccaaaaacaa tcggaaactt
     6421 tctactgaaa catggtgatg gggagttgac gttggataaa aaagcaattg aaggaatggt
     6481 tcgttctcac ttgcatgaag atgaattcat ccattcacca aaagtaaatg tcaaagcaac
     6541 gaaaaacaag atcgccgtca atgtaaaagg ggagttgaaa cgaacttcag cactcattgg
     6601 taaaacagga acattgatga aagaaatcga aaatgaagta caacacatat tgggaacaaa
     6661 agagccagtg aaagtatcgg tgaaatacac aggctttgaa gaaccagcta aacgaagcaa
     6721 tgaccgcaaa cgagtagaat agggggggac caaaaatgaa agaactattt tcgacataca
     6781 agctccctat catctttggg gtacttggat tgatattagc cgttttatgg atcaccgtgg
     6841 gctttttcaa gaccttattg atcttgatca tggcagcgat cggcgtcgct atcggttttt
     6901 atctgaaaca aacgaaaatc ttagatcact attttaaatc ttaggaggaa acatccatga
     6961 ataacaataa caaaaataat aacaataaaa tgaacaacca aaaaccagtg tctgcacatc
     7021 cagacccaac gacaccaaac caatcaaatg gtgtgaacga tgaaaagaac aaaacagcac
     7081 cagtatctgc acatccagat ccagtagtcc ctaacgttca acaaggagta gaagagaaga
     7141 aacatgatgc agaaaagcat gcacctcatc atccaggaac tccagaatct aaagttccag
     7201 aacaacatga tgcaatcgat ccttctaaac ctgtggaaga gcaaaaacat ccttctgacc
     7261 atgcgaaagc acaagaaaaa cttagttctg accacacaaa cggacaagga aaacttggtt
     7321 ctgatcatac aaataaccaa ggaaagcatg attctgaaca ggaagattca atgcgcggtg
     7381 agctgaatta tgaagataaa gttgtgcaaa aaatcatcgg aatcgcaatt gaacaagtag
     7441 acggtttatt atctgcaaac ggtggtttct tctctaatgt ggcaggaaaa cttgtgaata
     7501 cagataatgt aacggctggg atcgaaacag aagtcggtaa aaaacaagta gcagttgata
     7561 tggatgtcat tgtggaatat ggcaaagata tcgaaaaaat ctttgaagaa atgcaagaag
     7621 taatcggcaa agaagtaaaa aatatgacac atttagaagt gatcgaagtc aacgctaacg
     7681 tagtggacat caaaacaaaa gaagaatttg aaaaagatca agaaacggtg caagacaaag
     7741 taactgacgc agcgaaaaaa accggtgaat ttgcttcgaa tcaaacagat aaagtaaaat
     7801 cagcagctgg aagcggcgca caaaaagtaa aagaaaatac agaaccacgg gttcagtaat
     7861 aaggaagtaa aacattagga ggaacgaaac atgggattta tttggtcact tatcgtcgga
     7921 ggaattatcg gagcaattgc aggagcaatc acgaataaag gttcttcgat ggggattatt
     7981 gcaaatgtcg tagcaggttt agttggatca gcacttggtc aagcattatt aggttcttgg
     8041 ggaccaagta ttgcaggaat ggcaatcgtg ccatcattga ttggtgccat cattttagta
     8101 ctaatcgtat cattctttgc tcgaaaactg taaaaagact tttaaaaaga ggtcgtgaaa
     8161 aagctgttct tcatcaagta ataagaacag ccaaacaaaa atagcttctc atatttttca
     8221 tttggttggg catattatcg aagatgcaag cttttgaaca ctgtttatac ggaataagag
     8281 gctgtgacaa gacttttgtc acagcctctt atttatgcgg gcaaattccc aattagattt
     8341 ttaaaagttt ttccttaaat gtgtctttat tgatacagag aagcttcttt aataaaacaa
     8401 tgcctcccta aattttcttg agataggaaa ggtgaacata caaaataata cgaccacttt
     8461 gaaaacccag atgatccaca aatggatcgt atgatactga tgaagtaaaa agcaatggat
     8521 cagaaactca aagagattga aaaagacaag gaagaaataa tatctctttt ttactcttgt
     8581 ctgttttagc caataatagc tcgtaaagta atctagacaa acaaatagaa gtaaacaaag
     8641 tttcgtaaga gcagcaatcg tatcatgttg ctctgctaga cgattgacga gcaggaaaaa
     8701 tgttggtaat ggaatataga tcacgagtaa tgaaagaaaa aagtaaacaa taaatggcat
     8761 actattcctc ctaattgtgt gagttcgccc tcattttaaa ataacgatat ttgtttgtga
     8821 agctttttcg tgtcgtaaca aatgttatct aatgtatttt taaataaata atcattatta
     8881 tca
//
LOCUS       DAFKHN010000099         8647 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFKHN010000099 DAFKHN010000000
VERSION     DAFKHN010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.099"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(41..637)
                     /locus_tag="LY912_002487"
     CDS             complement(41..637)
                     /locus_tag="LY912_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBM6956132.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            987..1331
                     /locus_tag="LY912_002488"
     CDS             987..1331
                     /locus_tag="LY912_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBM6956133.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            1332..1751
                     /locus_tag="LY912_002489"
     CDS             1332..1751
                     /locus_tag="LY912_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBM6956134.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1843..2193)
                     /locus_tag="LY912_002490"
     CDS             complement(1843..2193)
                     /locus_tag="LY912_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956135.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(2159..3490)
                     /locus_tag="LY912_002491"
     CDS             complement(2159..3490)
                     /locus_tag="LY912_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBM6956136.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3745..4311
                     /locus_tag="LY912_002492"
     CDS             3745..4311
                     /locus_tag="LY912_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6956137.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            4456..4543
                     /locus_tag="LY912_002493"
     tRNA            4456..4543
                     /locus_tag="LY912_002493"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4488..4490,aa:Ser,seq:cga)
     gene            4879..5853
                     /gene="bsh"
                     /locus_tag="LY912_002494"
     CDS             4879..5853
                     /gene="bsh"
                     /locus_tag="LY912_002494"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBM6956138.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            6178..8073
                     /gene="asnB"
                     /locus_tag="LY912_002495"
     CDS             6178..8073
                     /gene="asnB"
                     /locus_tag="LY912_002495"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBM6956139.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(8268..>8647)
                     /locus_tag="LY912_002496"
     CDS             complement(8268..>8647)
                     /locus_tag="LY912_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBM6956140.1"
                     /translation="IDIANALLDEGYPDNRAIPIAIDQAKKWYEDASESEKRTFEKEK
                     NPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKSKGAKKASNHFDTKKEAIEKGKQV
                     AQNKESTLFIYKKDGTKEKEIDY"
BASE COUNT         3051 a         1466 c         1617 g         2513 t
ORIGIN      
        1 ttaacattgt caatcaatga ctaattttac aaaataaata ttatccaaga agaccactta
       61 gatattgacc tccataaatc aaggccatac tatataagaa aatcgacagt ggtttagcaa
      121 tcaaaatgat tagtgtatat cgtttcactg acatgtttgt caatccagcc atcaaacata
      181 acgcatcgtc aggagcaact ggaagaaaaa tagctagagc aaacagcttc tcaaaacggt
      241 tttgattatc cagccagcca atatatttgt tatatgtctt atcgctaatc atggaaagta
      301 tgaatggctt tccataacga cgccctagca gaaaaatgat aatcgaacca atgcagattc
      361 caatatagtt atagataaat ccagcataag ggccaaatat caggacacca gctgcagtac
      421 tgatccctcc aggaatgatt ggaataacta cttgcaggat ttggatgaag acaaaaataa
      481 tcggtcctaa aatgatggaa tcacctacta atcctcttaa cgcattcaaa tctttgaaaa
      541 cacctaaatt aataaaataa atcgtcagcg cgattgatag gcctaatccg ataatggata
      601 tgaaatttat cagttttcga gaggcagcaa tattcattat tcatcaactc cttagaggtt
      661 ctttgttaac tatactttac tagaaaagca actaactgcg ccattttttg atatgacaga
      721 aaacaaacaa ttttgtaagt tcatcataag tataaaagat tgatctcaaa aaaacatcca
      781 actaaagact tatttaataa cttgtttttt ttaaaataaa aaaagcgtta gcaactatgc
      841 ttaaaaagca tatcgactga ataaactaag cattggacag gctgaaagac tacatttaaa
      901 atgaaatgcg aagaaacaat agaaaataaa gttgccttag aaccatagtt gaatcaccta
      961 acagtcgtga agggagaata agagaaatgg cagaaaaaca aaccgcagga cgagatcaat
     1021 taggagattt tgcaccaaaa tttgcagaat taaatgatga tgttttattt ggacaagtat
     1081 ggtccagaga agaattatct gctcatcagc gtagtatcat caccatatct gcattaattt
     1141 caggaggaaa ttttgaacaa ttgccagctc atctgaagat tggcaagcaa aatggcatta
     1201 ctagtgaaga aatagcagaa atcattaccc atttagcttt ttatgtagaa tggccaaaag
     1261 cttggtcagc ttttagttta gcaaaagaaa tctatttaga agaaaatagc gaagataaga
     1321 aagaggcgta aatgatgaca aaacacgaag aaatacacaa tggcgtgatt tttccagcag
     1381 gtgaaaaaaa cgaagcttac gctcaagtat ttaccgggca aagctatctg aatatgttag
     1441 tgaatgatcc cgaagtttct gttggtgtag gtaatgtaac ttttgaacca ggttgtcgca
     1501 atcactggca tgtccataca gacggctatc aaatcttact tgtgaccgga ggagaaggct
     1561 ggtatcagga agaaggaaag ccagcaagac gattaatggc tggagatgtc gtcgtaacgc
     1621 acaaagggat taaacattgg catggtgcga caaaagacag ttggtttgaa catttggcga
     1681 tcactgctgg taattcagag tttttagaac ctgtaacaga tgaagtgtat gaaggattgg
     1741 aaaatcaata atgtcaagct tgaacagctc ctgaaagtag attttaatcg aactttcagg
     1801 agctgctttt ttgattcagt cttttataaa tagaaaatag ggttaataat aggaatgaga
     1861 agcacgtcga aagatcttaa tattgataat cggctgggca tacatgattt ccacgtcatc
     1921 aatcaaacta cctaacagat gataatcttc ccgatcatgt cggggattac ctaatagttc
     1981 ttgatagtag atttccatac tagggtcccg aggattgttc agcaaatcag caagtacatc
     2041 taaatcttct ggctgagttt ctgccgtacc ctgtatctct atgaaaagcc cttcctcagc
     2101 aaattctact ccaatacgta tttcagttat ttcatgggaa tataaataag taagaagctc
     2161 atcgatgatt ctttttgata attctttttc caagtgtctt tttttccttt ctgacagcgg
     2221 taaagttatc tagtatcggt acaaggatac ctgcaacgaa accagttgaa aaaccactgt
     2281 tatatagatt tagtcctccg tgcaaagtgc tgacgttatg gacaagagca atatgtagca
     2341 caccagctat tacaccgtaa aaactgccgt aaaaaccgct tatgggcgca agacctgtcc
     2401 caaacacagc tgcaacaagc atgccagtac tggtgatctc atgaaaagtt ccaaacaaag
     2461 aagcaataaa tattccgact agtatcggaa aactgttttt taaatgacaa ccaaaagcac
     2521 tgaaacccac cgcagataaa atagcaccga tgacaggtcc atttaactga ccgccaacca
     2581 gcaaaacata agaagacagc atcagaccaa ctaagcccat gttgatcaaa gtagcaccaa
     2641 taccagaatt agcaatgaaa tcagttgtca attttccaga tgaatcgaaa atttctcgaa
     2701 tccccgaaag ccgaaaggaa ttataataga aaccaattcc gactgtcagc gaaaaaaagc
     2761 caaaaataat ccaaatgaga ggaaagtgat attcattgaa aaccaatgta ttttcgacga
     2821 ttgaatagct gaataacctc aaaacagcag taaaagtcat cgcaatcaac ccagaggtga
     2881 atccaatatt ataaagtgtg aatccacgat ggaaaactaa agtttgagca gctaagggcg
     2941 gaagaagtat accaattgct atgccagcta aattccccaa taaaatacct atcagtaaag
     3001 gaaaacgcat accaaaagtg atataactaa cgaccggtga taatacgcta ccaaacagtc
     3061 cgatcatgat gtactgagaa aaaggtttat tgacaaatac agcgtataga tacacaccta
     3121 aaatgattga gatagaatta taaaggtttt tgccaaaaaa agagaaaccg gtaactgtta
     3181 gaatcgaagc aaataaggga ccgtttaaaa tcaccttgtg ccgataagct aaaagcacag
     3241 aaagtaaggt caaaatccct acatttatga atgcgcttcc gaaaacacct aaagcaaaat
     3301 aatctgtcaa aagattgctt ggcgaggtaa gaatagttag caatccactc caattatcag
     3361 taggagtatt agaaagcaag ccaataaaaa gaaaaaaaac acctgtaaaa ccaagataaa
     3421 aatactttct tttctgtgaa acgattcgtt tttgaggatg aatataaata acgtcagttt
     3481 cgttttccat tacacacctt ctttttcatt ttctttaact ataacttgaa atgaaagatt
     3541 tggacaacta tcatttaggt caaaactaaa aatgtaaggg aacccattga atttaaccaa
     3601 atttttttaa ttttgcaaaa aaaagttaaa gaagactgaa aaaaatttaa aatataacgt
     3661 tttgagtaaa atgtttgcaa aaaatgctaa aaatagggta caataaaaca acatatactg
     3721 cagtaaagaa gtgggggagt tttaatgaga agaaaagtct ataccaagga tcaaattcta
     3781 aaagctgctt atgatgttgt tgcaaaggaa gggtttaaag gatttactgc gagaaatatt
     3841 gctaaaaaga tggggatttc gacacagccg atttatctgg aattcaaaaa catggaagat
     3901 ttaaaaaata cgttgctgga ttctatcttt gaacaactaa aagaagatgt tttccctatt
     3961 gaacgtactg gtgataaaat cattgatctc ggtttgaact atatctactt tgcaaaaaag
     4021 catcatagtc tttacatggc attgtacatt gatgaacatg gggacggaaa gaaaatgcat
     4081 gatttttcat acaattattt ccgtgaaata gttaaagaag atgaaagata caatcaatta
     4141 tcggatgaat atgtcgatgc tctgcatact ggtacatggg tagcagtgac tggcttagcg
     4201 tcattgatgt catcaaacat catgcatcca acagaagaac aaatcattgc actgatcaaa
     4261 cggacaattg actcgatttt agcattagat aatcctgaaa taatcagata gtgttctatc
     4321 agtatgaatt tgatcggtaa gtccgttggc tgcaaactgt caatggactt ttttgctaaa
     4381 aaaagcgatt tctgttattt atctattaga aataggcttg acatttcgtg aaaaaagttt
     4441 aaaaatagta cttacggaag gttggcagag tggtaatgca ccggactcga aatccggcga
     4501 accggctaat accggcgcgc aggttcaaat cctgtacctt ccttatatca acgattagag
     4561 gttgtgaaga agctgtcctg catcaagtaa taagaacggc caaacaaaaa tagcttttcc
     4621 tattttttcg tttggttggg cttattaccg cagatgcaag cttttgaaca ccgtttgttc
     4681 ggaataaggg gctgtgacaa gacttttgtc acagcccctt attgttgtac ttttaaccta
     4741 caatattttt tgattccccc tgagtactat tttttataaa tgctagtaaa tcaatcttct
     4801 ttggcctttt ttttgataaa aaaaaatact agatgtaaga taaaagtgta aaaacgattt
     4861 gttttaggag ggaaaacgat gtgtaccgca atcacttatg caacgaaaga ccattatttt
     4921 ggaaggaatt ttgattatga gatgtcttat aatgaagtag tcactattac tccaagaaat
     4981 tatcgtttcg attttagaaa ggtaaaaaat ttagataaac attatgcaat gataggaata
     5041 gcagctgggg tatccaacta tccactctat tatgaggcta caaatgaaaa agggttgagt
     5101 atggcaggac tgaattttcc tggcaatgct gattataaag aattacaaga aggaaaagat
     5161 aacgttgcac catttgagtt tattccatgg atactagggc aatgctcaac catagacgaa
     5221 gctaaagaat tattggctac tatcaatcta gtcaatatcg attttagtga aaaactaccc
     5281 ttgtcacctt tacactggtt attagctgat aaagaaaaat cgatagtaat tgaaagtatg
     5341 aaagatggac ttcatttata tgataatcct gtcggtgtgt tgacaaataa tccgccattt
     5401 gattatcaat tatttaatct gaacaattat cgctcgctat caaatggaac accagaaaat
     5461 catttttcaa accagatcag cttgaatgtt tatagtcgtg ggatgggagg attgggctta
     5521 cctggagatc tctcttctgt ttctcgattt gtaaaagcca catttactaa aatgaatgct
     5581 gcatcaggtg attcagaatc tgaaagtatc agtcaatttt ttcatatact aggctcagtc
     5641 gagcaacaaa aaggagtatg cgatactgga gaaggaaaat acgaatatac gatttattct
     5701 tcttgctgta acgttgataa agggatttat tattatcgta cgtatgaaga cagtcaaatt
     5761 actgctgtaa atataaataa agaagacttg gatcgtcatg aattggtcag ttatccagtc
     5821 ataaaagagc aacagataaa ctatgtcaat taattaatga atagatccgt ttggtatcat
     5881 attttctgat acagtcataa ttagacacga tctttaggtc gtgtcttttt ttgctgtttt
     5941 ttttggaaat agcatccact aatatttttt taacacgaag agaataaggt agcctcaaaa
     6001 aagaaaacat ggtaaattag atattgggac tttattttct gtaaaaacag aaactttcat
     6061 cttttgtttt cacgtgacga aattgtaaga gagaaaatat tcgtccgcta tttattctat
     6121 gataagatgc atatgaatga aataaacagt aattttatat taggatgtga aagttaaatg
     6181 tgcggtattg taggttttgt taacgacaag gacaacaaaa aaacaattat taatacaatg
     6241 atggatcgaa tcgttcaccg tggacctaat agttcaggag aatatatcga taaacatgtt
     6301 gctttaggat tcagaagatt aagtattatt gacttagagg gcggtactca gcctatttac
     6361 aatgaagatc ggacaaagat cattattttt aatggcgaaa tctataatta ccagcctttg
     6421 agagaagaat tgattgcagc tggccacgtt tttcaaacac atgcagatac agaagtcctt
     6481 ttgcatggtt acgaagaatg gggaacagaa ttattgcaaa agatccgcgg aatgtttgct
     6541 tttgctattt gggataatga aaagaatgag ttattcggtg caagagacca ctttgggatc
     6601 aaaccatatt attatgcaga aatgaacgga acatttatgt ttggttcaga aatcaaaagt
     6661 tttctgcctc atcctgattt taacaaagaa ttgaacaaag aagcgttgaa accttatatg
     6721 actttccaat attctccatt aaacggcgaa acattcttca aagatgtcta tcgtttgcct
     6781 gaaggccatt attatacgta taaagatgga aaactagaca ttcagcaata ttgggatgca
     6841 gattttgaaa caaaagaaac gcattcccga caagaatgga tcgaaaaaat cgacgaaacc
     6901 gttcaagctt ctattgaagc acatacggtc agtgatgtag aagttggttc tttcttatcc
     6961 agcggggttg attccagtta tgtaacctct gtattgaaac cagatcattc tttctcaatc
     7021 gggtttgatg ataaaaccta taatgaagcg attgaagcca gaaaactaac cgaactattg
     7081 gacttagata atacagcagc agtgatcgac ggagacatgt cgttcaaagc attccctttg
     7141 atccagtatc acttagatga acctgattca aatccttctt gcgtaccttt gtacttttta
     7201 gcaaatcttg cttcacaaag tgtgcgggta gtccaatctg gagaaggggc ggatgaactg
     7261 tttgcgggat accaaacgta tggattccat acgaattcaa aattcatccg tgtgattgct
     7321 caaggattga aaaaattacc aaaaggaaca cgctataatt taggacgtaa aatcggaaaa
     7381 atgaaaaatt tccatggacg gatccattta tatgaatcac ttgctcctgc aaaagaatat
     7441 tttatcggtc atgctcgagt gttcgaagaa tcagaagcat cagaagtgtt aacaccaaaa
     7501 tatcaaacag caccatctgt ggatgaaatc atgactgttc attacgagaa aacagaagga
     7561 atcaaagatg aagtcaataa gatgcaatat gtcgatcttc atcaatggat gccaaaagat
     7621 atcttgttaa aggcagataa actttctatg gcaagttctt tggaagtccg agtaccttta
     7681 ttggatatcg aagtcatgaa attggctcaa caaataccaa gtaagttttt attgaatcaa
     7741 aacaacacaa aagatatttt cagacaagct gcgaacaaac atcttccgga agaatggtcg
     7801 aatcgtgtga aattaggatt ccctgtgcca atcaaagctt ggttgaaaga agaacacggc
     7861 tacgaacaag tcaaagcatt attcgaagca gattttgcaa aagaattttt tgatcaagaa
     7921 aaaatcatga agttgctaga tgaccatcac gaaggacgta aagaagagca aagaaaaatc
     7981 tggacaatct tcagtttctt gacatggtat aaagtctact ttgtagatga aacgattccg
     8041 caagcagaag caatcgacta tgtgactgtt tgatgaaaat caaatatcaa taaaaaagag
     8101 gttttctcct accgtttaac actgagtgat aagaaacaat ttcaaaaaac agctcttccc
     8161 gttttataga tattatgact tatggttcgg agttggcaga ggaacaccat tgtttcgaac
     8221 ataagggggt tgtgacacga ttttcgtcac aaccccttta catatgttca ataatcgatt
     8281 tctttttctt ttgtcccatc ttttttataa atgaacaaag ttgattcttt gttttgtgct
     8341 acttgctttc ctttttcgat tgcttctttt tttgtatcaa aatggttgct tgcctttttt
     8401 gcccctttag atttcacgat ccattgttct tcctcatatt ctacgatcac atctgaatca
     8461 agcagttttc cagcacgagg attcgtatcg tgttcatccg tcttgcttgg atttttttct
     8521 ttttcgaaag ttcgtttttc tgattcacta gcatcttcat accatttttt tgcttgatca
     8581 atggcaattg ggatcgcacg gttatcaggg tacccttcat ctaataatgc atttgcgatg
     8641 tcgattg
//
LOCUS       DAFKHN010000100         8635 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFKHN010000100 DAFKHN010000000
VERSION     DAFKHN010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.100"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..485
                     /locus_tag="LY912_002497"
     CDS             <1..485
                     /locus_tag="LY912_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956141.1"
                     /translation="VSSKKNFNQKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIA
                     SLENKEHIIKHEAKIGSQWVNLPYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEIN
                     HQPVKEQVNANGLVQISGVKGVADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR
                     "
     gene            660..1493
                     /gene="msrA"
                     /locus_tag="LY912_002498"
     CDS             660..1493
                     /gene="msrA"
                     /locus_tag="LY912_002498"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBM6956142.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            1606..2562
                     /locus_tag="LY912_002499"
     CDS             1606..2562
                     /locus_tag="LY912_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBM6956143.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            2851..3549
                     /locus_tag="LY912_002500"
     CDS             2851..3549
                     /locus_tag="LY912_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBM6956144.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            3699..5015
                     /locus_tag="LY912_002501"
     CDS             3699..5015
                     /locus_tag="LY912_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6956145.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            5032..6447
                     /locus_tag="LY912_002502"
     CDS             5032..6447
                     /locus_tag="LY912_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBM6956146.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            6911..7231
                     /locus_tag="LY912_002503"
     CDS             6911..7231
                     /locus_tag="LY912_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6956147.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            7257..7574
                     /locus_tag="LY912_002504"
     CDS             7257..7574
                     /locus_tag="LY912_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBM6956148.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            7603..>8635
                     /locus_tag="LY912_002505"
     CDS             7603..>8635
                     /locus_tag="LY912_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6956149.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVL"
BASE COUNT         2871 a         1390 c         1809 g         2565 t
ORIGIN      
        1 ctgtttctag taaaaaaaat ttcaatcaaa aaataatttc tcagccggga catattgttg
       61 taaacaaaga aacagtagag gcgtatacca ctaaaggaat ggattatttt ttatatgatt
      121 attctcctat cgcttcattg gagaataagg agcatataat aaaacacgaa gcaaagattg
      181 gcagtcaatg ggtaaacctt ccttataaaa caactggtag ttctatcata tatagagtaa
      241 ctaatgagaa gagccaagta atcacacttc ctgtatatgc ttatttagga acgaatgtag
      301 aaataaatca tcaacctgta aaggagcagg tgaatgctaa tggattggta caaataagcg
      361 gagtcaaagg agttgctgat attaaagtaa gcacaagtta tacagtaacg actattattt
      421 cttatcttgt tacattaact gcatatttat gtttattttt taaaatagtt ttccataaaa
      481 ggtaaattaa cttttcattt ataaaataaa ttgattaaaa aggagaatct gtcgataagg
      541 attctctctt ttttatacga aaaatctgta gggggatgaa gtaatcgctt atttcctcac
      601 tttatgataa attacagcta aagtcactag cttgtcttct tcggaaagga ggagaatcta
      661 tggatgagga acaaatattc attcaaacac tttataatct gattttgaat ccgaatacac
      721 gagattggga acgaaaagta ttgattcaga caaagaatga cataagagaa aatatatccg
      781 ttaaagaaca gttatcaaaa ctagaagcaa cactacgtcc attagctatc cgaatgaatc
      841 tgacgcctga tgtaatggac ttttatttat tgattacgga aggatttgat aaggagcaaa
      901 aatatgactt ttccaagcat gccatgcaag atgctgacta tcaagaacgt gcagtatttg
      961 cagggggatg tttctggtgt atggtcgagc cgtttgaatc gaaaaaaggg atcctatctg
     1021 ttttgtcagg atacacgggc ggacatgttg aaaaaccaaa ttatgatcaa gtaagtggtg
     1081 gttacacagg tcatgtggaa gctgtggaga tcatttatga cacaagagaa ataagttata
     1141 gcgagttgct gacaatctat tggcaaatta ctgatcccac agatacattt ggacaatttc
     1201 aagatagagg gaagcaatat cgtccagtga ttttttatca agtcgaacga caaaaagaat
     1261 tagcggaaca atcaaaacag aaactagaca gttcaggaac tttccaccaa ccaatcgtca
     1321 caaaaatcga accagccggt acgttttggc cagcagaaaa ctatcatcag caattttaca
     1381 aaaaacaacc gaaacgttat aaaaaaatcc agcaagcacg taatcaattt ctgatctatc
     1441 aacgagtaaa aaacaaatgg caaaaaaata tacgaaaaaa tcattttgat taactccttt
     1501 tctttaaaat gtagtaaact aaaaatagaa aaaagaaagc gttttaaaaa gatttgatga
     1561 ggaggagaaa aattgtatat tgcagatagt gcacgttatg aaaaaatgga atatcgtaaa
     1621 tccggtcatt caggtttgaa attaccgatt ttatctctcg gattatggca aaattttggt
     1681 gattatgatc ctatccataa tcaaagagag attttaagag gcgcattcga catgggaatt
     1741 acccatttcg accttgcgaa taattatgga ggccctgctg gagctgcaga gaaaaacttt
     1801 gggcgtattt ttagagaaga ttttcaagcc taccgtgatg aactgattat ttctagcaaa
     1861 gcaggttatc atatgtggga agggccatat ggggaatggg gctctcgtaa atccatcatt
     1921 tcaagttgtg accaaagtct ccaaagaatg gggctagatt atgttgacat cttctatcat
     1981 catcgcccag accctgatac acctttggaa gaaacagcag aagctttgat gcaacttgta
     2041 agacaaggaa aagcattata tattggtata tccaactata atggagaaga tacaaaaaaa
     2101 atgactgaaa ttttaaaaag aaaggaagca ccgttcatta ttcatcagat gcgctacaat
     2161 atgttttctc gtgcactact agaagacgat ctatctccag tattagaaga agaagggcta
     2221 ggggcaatca cgttcagtcc gcttgctcaa gggttgctga caaatcgtta tctacatggt
     2281 attcctgaag attctagagc acatcgtaag gaaataccat tcctttcaga agaacaagtt
     2341 ggatcaactc tggaaaaaat caaagcactg caaacaatcg ccgtatcacg aggacaatca
     2401 ttagcgcaaa tggcccttgc atggaatttg cgacaaaaat ctgttacaag tgtactggtc
     2461 ggagcaagtc ggttaagtca gttacaagaa agtgttcgaa tgatggataa tttagatttc
     2521 tcaccagaag aagaattgag aatcgaccaa attctagaat agaaacgatg taatcaaact
     2581 ttttatccat atattaaaaa aaacaaaaga tgacatcaag aatcgaatga agatcgtctg
     2641 ttattgaaca tcatattttt tgtcgttcaa aataaaaatg atcgaaggct aggagtgaat
     2701 tttatcctag tcttttttat ggtaaatatc ttcttcgttt gtatgtctat gaacggatta
     2761 atcaattttg tatacaaaaa atcatcagat gattcaaacg tgttataata attacgaaaa
     2821 aatacatcag atgaaaagga ggtatgtggt ttggaagaaa ataaaaccct agtagaagta
     2881 actactgaca agatccttag atatttaaag gaaatgcagt tgcaagtagg agataaactg
     2941 ccgaatgaat atgaattgtc cgattattta gaggtggggc gaagcacggt gcgagaagct
     3001 gtgcgggctc tagcttccag gaatatcctt gaagttcggc aaggagcggg gacatttgtc
     3061 agtgataagc gagggattgc caatgaccca ctcggttttt ctttgattga agatcaggat
     3121 cggatgatac gagacttatt tgaactgaga tatttattgg agcctaagat ggcaggtttg
     3181 gcagcggaat atgcaacgaa gaatcaaatc gtccaaatga aaaaattaac gcaaaagatt
     3241 gaaacttctt ttcgagaagg cacacaagaa catgttcaat tagacatcga ttttcatacg
     3301 atgattgcag aagctagcgg aaacgtagcc ttgctgcata ttatcccaat cattaatgaa
     3361 tcaattgctt tgtttaataa aaattatgat atccagcatc tgaaaatcga gacgatcgat
     3421 attcatacag agatcgttca ggccatcgaa aggcggaatg cacttgctgc gtttgatgca
     3481 atgactgtcc atatggcaat aaatcggaga gaattacaga aaataatagg agaaaaagaa
     3541 actaattgac agttcatctg atgtatttta tgataaatac atcagatgaa tttttgtttt
     3601 atatttggta aaaaagagga gtaaatagtt tctgttcatc gaaatgtaag cgctgactaa
     3661 tagacaaaaa gagatgacgt caaggagaag aagcaggaat gaggggatct ggaatgagtt
     3721 ttatggataa attagccaat gttttaggga acgtggcaac gagaatcaat aatttaaggt
     3781 atatcatggt gataaaaaac gcatttgctg cattgattcc ggtaattatt acgggtgctt
     3841 ttggcacatt gttttcagca atggtctttg actcggaaaa tggcttagca cagataagtt
     3901 tcttgcgttt tttagaagaa ttaaagccta tcgcatctgc catcagctat gtcacactaa
     3961 gtttcttgac catctatgct gtttttctga tagggatcga attagccaag ctgaataaag
     4021 tggatggtgt attccctggt atcatcgcag tgatgtctta tttatctgtt aatccaactg
     4081 tttatgaatt agtgaatgaa aatcagactg ttatagtaga aaacgtattg gctaaacaat
     4141 atacagatac gaaagggtta tttttgggaa tgttggtctc catcctttct attgaacttt
     4201 attgctggtt gaggaaacag aagaaactac agctgagaat gcctgatacc gtgccaacga
     4261 atgtttctgc tagtttttct gctttattcc cgacgattct gactgtatcg ggtatcgcgg
     4321 ctgcgggatt tatcatcaaa gaacttacag gaatgtacct ttatgatatc atttacaatg
     4381 tcgtacaacg cccattagaa ggtgtcgtac aagggttacc gggtattttg ctattgatgt
     4441 ttattgcgca agtcttttgg gtgattggta tccatggaaa tcaaatggtg aagccgatac
     4501 gggaaccgtt gcttttagcg gcaattgctg taaatacgga agcttttgaa gctggaaaag
     4561 aagtaccgaa cattattact atgccatttt gggatatgta tatgagtatg ggcgggtctg
     4621 gagtcacgat cggtttactg attgcagtat tgttagttgg aaaacgggaa gatatgaaac
     4681 aaatcaccaa gttatccctt gctcctggga tcttcaacat caatgaacca gttatttttg
     4741 gtatgccgat catgctgaat ccaattttag ctattccgtt tatcttaacg cctcttatca
     4801 ctggaacgat tggttatttt gcaaccgctt taggatttgc ggcgaaagca gttgtaatgg
     4861 tcccttggcc aatgccgccg atcgtcaatg cttatctggc aacagcagga aatatcggtg
     4921 cagttattac gcaacttgtt tgtattattg tttctatttt gatctatctg ccatttgtaa
     4981 aagtagcaaa tcgtgtggaa aatgatggga tctaaaaaac aggaggaaat catgaaaatt
     5041 actattccaa aaaattttat tcttggtgct gcatcttctg cttggcaaac ggaaggttgg
     5101 aaaggaaaaa aagaaggaca ggattcgttt atagatagct ggtataaaaa tgaacatttt
     5161 gtttggcata atgggtatgg cccagccgta gcaactaatt ttatggaaca ataccagcag
     5221 gatgtggatc tgatgaaatc catccatctg acacattatc ggacttctat caattgggct
     5281 cgttttttta ctgattatga gaactgtata gtagatgaag aatatgctca gcatataagt
     5341 gaaatgatcg actctttgat cgaagcagac gtagaaccga tgatttgttt ggaacattat
     5401 gaagtcccag cttttctttt ggaaaaatat gatggctggt cttcaagaaa agtagttgat
     5461 ttttatgcta agtatgctca aattgccttt gatcgttacg gtgatagggt aaaaaactgg
     5521 tttacattca acgaaccaat cgttccccaa acgcgttgct atttggatgc tgttcgctgg
     5581 ccgcatgaac aaaacacaaa aaagtggatg atgtggaatt atcataaagt tttagcaacg
     5641 gctaaagcag tagagattta ccgcagcgga aattatggtg gaaggattgg ctgtatttta
     5701 aatcctgaaa tggtctatgc tcgatccaat tctccagaag accaaaaagc tgcttatatg
     5761 tatgatttgt tttataatcg agtatttttt gatccgatgg taaaaggata ctacacagaa
     5821 gagttcctgg agttgtgtca aaaacaatcg atttatttcg atcctgcaac agaggattta
     5881 gaaacgattc agcatcatac agtagatttc cttggaatca atcaatatta tcctaaacgc
     5941 gttcgcgccc ctcgttatca atggaatgaa gagacacctt tccatcctga acgatattat
     6001 gaagtctttg atttacctgg gaagaaaatg aataattcca ggggatggga aatctatccg
     6061 aaaatcatgt atgatatagc catgtatcta aaagaaaatt atcataatat cccttggctg
     6121 ataacagaaa acggtatggg aagagaatat gaagaacagt atatggatga gaaaggaatc
     6181 gtgcaagatg attaccgtat cgaatttatc ggacagcatt tgcattactt gatcaaagca
     6241 acagaagaag gcgcaaattg cgaaggctat atgttatggg cattcactga ctgtgtgtca
     6301 ccaatgaatg catttaagaa tcgatatgga ttagttcgaa tcgaattgaa cgatgaacga
     6361 agcagaacat tgaaaaaatc tgcttcgtgg tatcagactt tgattgataa gagagaattg
     6421 gatttgcctg acgaaatcta taaataaata gaagtttttt gtagatgttc attgtattta
     6481 ctggttattt gaaataaaag aggttgtgaa tccagcgttt tgagctaata cccagggtca
     6541 gctgattgaa caccgtttat tgagaggttg tgaaaaagct gtcctgcatc aagtaataag
     6601 aatagcaaag taaaaacaac atcttatgtt tttaacttgg ttggacttat taccgcagat
     6661 gcaagctttt gaataccgtt tatttgaaaa aagttgtgac aagttttgtg tcacaacttt
     6721 ttttgtgcac gttaaaagaa aaaaggtaat aaaaattaat ttgtgtgttt agtgtgcgct
     6781 ttctttttta gtgtgtatgc aacttggtat agaccttaaa tgtgatgata tcaacttttt
     6841 aaagcgcttt taaagttggc acgctacttg cttatataca agtgtaagta tagaaaggaa
     6901 cgtgtttaaa atggaaaaga aaacaatcat gcttgtatgt tcagctggaa tgagtacaag
     6961 tctcctagtc acaaaaatgc aaaaggcagc agaagcaaaa ggaatggaag cagacatctt
     7021 tgctgtatct gcttcagatg cggataatca actagaatct aaaaatgtag acgttttact
     7081 tttaggaccg caagtacgct ttatgcaaaa tcaatttgct gaaaagctag cacctaaagg
     7141 cattccttta gatgtaatca atatggctga ctatggcatg atgaatggtg aaaaagtact
     7201 cgaccaagca gaaaaactaa taaacaaata ataaaaatta tcggaggata caataaatgg
     7261 aagatcaaaa aaatctagaa gccatcatgg gtctgatcat gtttggcgga aatgcaaaaa
     7321 gcgatgcaat ggaagcgatt gctgctgcga aaaaaggtga tttcacttta gcagatgaaa
     7381 aaatcaaaga tgcagaggaa tctttagtcc aagcacatca ctctcaaaca gagatgctga
     7441 cacaagaagc acaaggaaat cacgttgaag tcacgctttt gacggtccac agtcaagatc
     7501 atctgatgac atctatagct tttacagatt tagcaaaaga gatcattgat ctgtatcgtc
     7561 gattgaacgc gtaatctaca gtaaagaaaa gagggaagat ttatggataa atttgttgca
     7621 tttatggaga aacattttat acctgtagca tcaaaaattg gtgcacaacg gcatttagtt
     7681 gcgattcggg actcatttat ggtgagtatg ccgttaatga tcttaggagc attagcagta
     7741 atgatcaata acttaccgat tcccgggttc caagaattga tgaactcaat ttttggtggt
     7801 gaatcatgga aaggattcgg ggctgctgct tggaacggta catttgccat tctttctgtc
     7861 ttgattgctt tcttgcttgc ttatcattta gctaacggct accgaaaaga cggtgtttcc
     7921 gcaggtgtga tttctttagg ctctttcttc gctttaggcg gagcattagg tatgagctca
     7981 aacggtttgt ttattgctat tattgttggg attatttcaa cagaaatctt tgtacgttta
     8041 agcggaaatg aaaaattgat catcaaaatg cctgatggtg tgccaccggc agttgcaaaa
     8101 gcatttgctt cattactacc agcaatgatc actatctctg cgtttgcttt agttgctgca
     8161 atttttgctg cattcggtgt tgatgatatc gtaggttctt tctatacagt ggtccaagaa
     8221 ccatttatgg gacttgcaaa ctcttatcca tctgccttac tgcttgcatt tatcacacca
     8281 ttcttatggt tctttggttt acacggagcg aatatggtcg atcctttgat gcaaacaatc
     8341 aatgcgccag ccattgaagc aaacgttaat gcaatcgcag ctggacatag cgcaccgttt
     8401 atcgtgaaca aacctttctt tgacagcttt gtcaacttag gaggaacagg tgcaacttta
     8461 ggtttactgt tagctattta tttagtagga cgtaaaaaca aaccatatat ggttgtaaca
     8521 aacttgtcga ttgcgccagg tgtcttcaat attaatgaac caacgatgtt tgggttacct
     8581 atcgtgttga acccgatcat gttcattcca tttattttga caccaatggt cttag
//
LOCUS       DAFKHN010000101         8421 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFKHN010000101 DAFKHN010000000
VERSION     DAFKHN010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.101"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(1..275)
                     /locus_tag="LY912_002506"
                     /pseudo
     CDS             complement(1..275)
                     /locus_tag="LY912_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(529..2164)
                     /locus_tag="LY912_002507"
                     /pseudo
     CDS             complement(529..2164)
                     /locus_tag="LY912_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2719..3282)
                     /locus_tag="LY912_002508"
     CDS             complement(2719..3282)
                     /locus_tag="LY912_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBM6956150.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(3297..4340)
                     /locus_tag="LY912_002509"
     CDS             complement(3297..4340)
                     /locus_tag="LY912_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956151.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(4473..4877)
                     /locus_tag="LY912_002510"
     CDS             complement(4473..4877)
                     /locus_tag="LY912_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBM6956152.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(5110..5745)
                     /locus_tag="LY912_002511"
     CDS             complement(5110..5745)
                     /locus_tag="LY912_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBM6956153.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSCNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(6011..7063)
                     /locus_tag="LY912_002512"
     CDS             complement(6011..7063)
                     /locus_tag="LY912_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6956154.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(7076..8014)
                     /locus_tag="LY912_002513"
     CDS             complement(7076..8014)
                     /locus_tag="LY912_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBM6956155.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
BASE COUNT         2704 a         1686 c         1330 g         2701 t
ORIGIN      
        1 aacattttac gccatgctcg cttcatttct tgtgggtatt taaatggttt cgcttctgga
       61 tgtttggctt tatatccttc gtaatcctta ctgttgataa ttgctttcat attaggaatt
      121 ggatcttcac ctggcatata ttgcagatta gaagcatgta attttttctc agaaacaaac
      181 cactcattgg aaaagacatg aatcaaatca tcacttactt gtgtaaaata gcgacgttta
      241 atgacaaaga tatcttcatt gctatctagt gtaccttcat ttctttgtgc ttaaattcaa
      301 agataatttt ctcaataaag atttttgatt ccagtaagat tcctttactc cttttacaac
      361 atagcgttgt cctttgtttt gaaacatctt cttcccctct ttgccattaa aaatagccca
      421 attctctata aagaagatta agcttcatta ttataatata aagtttaaat ttggtttatt
      481 acttactttt tcttattctc tagtaagcta atattgaaaa aaatgtaatc agatcattat
      541 ttttatatgt tgtaacttcc tgataagaaa actaattaaa agaaagaggt aactacataa
      601 actaattaaa aaagctaact tcatagttgg aggataaatg gaagaaactt caatgattgt
      661 ttctccttgt gttccttcaa tcgacactag tcctattatc aatctctctt ttttgtccat
      721 ttacttttgc gactgttccc caataatcaa atacaggaag cgttattttt tgtcctttag
      781 attcatgtac tgtatagact attttcgaat ccatcacttg ataaggcata gtatgccatt
      841 ccttgccaat tcttacttca tgattctgca aatgttcttt gtattgtaat gcttccgtgg
      901 gtgcatagtc ataaagtcct ccgggaagga gtgtcgtgta acgaataaga ttttcttgat
      961 tcattaccaa gtgatctctc tgagtgacaa ctttatgttc atagtttgct tttgttgcag
     1021 cagatacagc caacagtaat aaaacaattg ccgttatatt aactactttt ctttgcttag
     1081 ctgatgtgct cttcatgaaa acgaacgata aaatcaacga gccaaacagt acttgaaagc
     1141 ctaagattcg ccaaggaaat tgaatcattt gaatgggtgt attttgtaat aaagaccatg
     1201 gaaaaaattt ggtggataag agccaagaga ctaccgcact aaggtaaatc actttttctt
     1261 tgcgattaaa tcctttaaaa aagaagagtg gacagatcaa agaaataata ccaatgattc
     1321 ctaccgtaaa ggttgtcagg tcattattca tcgcaccaat caaactatcc gagacattta
     1381 atgcttggtg ttgtaaggtc gttttatctg gctcattaat cgattgaacc atgatttgtc
     1441 ggaacatcgg ataccaaaag tatgctgtta aaagaatcgt cattcctact gcctttgaca
     1501 actccacaat caaccggatg ctttcttttt ttcttgtttc acttactaca aagccgccta
     1561 agactagtaa gccaacggct attacactca taaaagtgga aagaacatgt gtataaatga
     1621 gtaagctcat actgactgct aatggaattg cacatggctt tttctcataa atcagtgcgt
     1681 aagcataata cataactatc ggtataaccg taagtgcaat cgcttcagca atagcagaac
     1741 gatgataaat atcaatcgta cggtacccat aaaatgtata taaacagcta aatataaaag
     1801 ccgcatcgat tctttttaaa aattttagtc cataatgaaa catcagcatg atagtacaaa
     1861 cattcaatag ccaaacatat aagatataac taacgattaa attattactt atccaataaa
     1921 aaatgactgc cggaaaaaag gtcaagtagg gataaaaata attcactccg ctcccataat
     1981 gattaaacgt cgtaaaattg attggaccag aaaaaattga agataaccct ttgactctag
     2041 caaaatggaa ggcaatatcc cccgatgtag aaatagtatg aacatttcta aaataattga
     2101 ttgaataaag tccagcaata attgctagga gaatggacaa tattattttt ttctttactt
     2161 gcattactta attatatact cctttcatgg attgctttat ctagtataac ttaaatttta
     2221 aataaatcgt tatttatttt tactctcact taaaaaagca ctaaaattat aagagaggga
     2281 ggtaatggtc tgaacaccaa gaattgttcc aacatcgaat tgcttaacta atgagttcaa
     2341 agcttaatta tgtggctctt atatttaccg agcgtggatt gcgatctctt tagcgaaaca
     2401 aacatctttc ataaaaaaaa cagccatatc cgctttcttg gatatgacta tttactacta
     2461 ctttactatc tttcattctt cttgtctcac ttatgataag gcgctgcgta tcatgagtga
     2521 atgatattag gaaaacttca taaaataaat cttttataca tttccacttc tagatggtca
     2581 ttcatgttag aagaatcaaa ctattttttt actgtcgtaa taatattaaa acactagaac
     2641 aaatcaatta aattccataa aatataaata atagacctag catcatctgg tataaaatgg
     2701 atgctaggtc cgttatattt actcaaaatt gattctacga atagatcttc ttatcatttc
     2761 tattttagta gtcatgcgtt gttgttcttc taaaggtggt aatggtataa gtagtttaga
     2821 taaatttgta ccatttacat ttggttgccc agttccgtaa gaaatttttt ctaataactt
     2881 ccaatataat ggcgagtcta agaagcagtc tacgtattct gataataatt tctcaactaa
     2941 cctaattcga atcaagtaag aagcaaaaac agattcctca cttatttcct taaccaagaa
     3001 actttttccc atagttcctc ctgtccttgc tatcaaaatg tcattttctt ccaatcttaa
     3061 atcaactagt ttagaattac taatatcaca gtaaggcaca ctggaccaat ttacacgtcc
     3121 ctcttgtata tctgtgattc tcaaaaactt aacattgcct tgttttttcg ccgaatctgt
     3181 atagccatat tgaatcttag tagaaatact tcctaaataa acccatagtc gaacatcgct
     3241 agatgatttt tcttgtcgtt ctttatgaac aacagtgatc atcttgagtt gtccgactat
     3301 tttttagttg cagcaatctt tttgggacgc ttatttgcat gaagcaacgt tgctaagtct
     3361 agtaataaaa cattggctaa cacaggattg gctttctcgc gatacgctgc ggcgccactt
     3421 tcaaacaata ctgctagacg atcttctaca acaacgattt gttccaaata cggtggaaat
     3481 ttgattcgtt ttaggatccg gctaggagag tcccgctcgg acactaagag ttccgaggta
     3541 taaggaccat aagaacgact ggctaagaga taatggccat aaaaagccac accttgaatc
     3601 ttatcagatg tttttctgct cattgtcacg gttggttgga ttttgtcttt gcggcgaatt
     3661 gctgttttca tttcagctat cgtcggcaat agatagaaag tcaactgtcc ttcacctttt
     3721 agtgtgaagt tgccagatac cagttgatca ttgttttgag tcaaatacga tgcttgtgga
     3781 atctctgaga gatcagttgt cagccaataa gcgattggct gtcccgtctc ttcagatgta
     3841 tctgctaaga tatcgatcaa acgtaaagcg gctactcgtc cagtagcaga tcctgtgatt
     3901 gtcaaccata aaagttcccg ttttgtatca tatactaagc cccctacatg tggccgttta
     3961 ggtaaaatca gcagtttgat cggctgtcct gtttctctat ccagtacatg aataatagaa
     4021 tgatgctgat ggtcatagca gtaggcagaa ataaacacaa aatcttgaga aaaagccaac
     4081 ccttgcggcg tcatccattg acaaacctca ttttcgccgg tttccggcac caccattctt
     4141 gtttctgtta atccaggaat gttatattgt tttgcttcag ccttttccca agctgcttga
     4201 acaataggat accgttttaa ctttttttca atatcctgat gtatccgttg ctgcttccaa
     4261 tgcttaaact ttaggacata gtaaacaaga aggccaatga ccagcaacac taaaatcatt
     4321 attgctaccc gctgtgtcat ttttttgcct ccttgttcta ttcgatcaat cgtccatata
     4381 ccgctattaa ttaccgtaac tacatgtttc ttttactagc gtttctttat aggatctttc
     4441 ataatctcat ttatagtaac attaagaatc ccttattcta ctatagtcac ttccacatca
     4501 atattgcctc ttgttgcttt agagtatggg caaaatgcgt gggcttcttc tgcgattttc
     4561 tctgcttggt ccttctcaag tcctggcaaa gaaacttcta aaacgacccc gatttggtag
     4621 cccccatctt ctaattgaaa taaagatacc cgtgctttga cttcagaatc agactcaaga
     4681 ttattttctt ccagcatgtg ttgaaccgcg ccgttgaagc aagatgcgta tccagccgca
     4741 aaaagttgtt ccggatttgt cccttcacta tggattcctg ggcggtcgat cttcatgtgc
     4801 atacttccgt ttggtgcctc aacttcgcca tcacggcctc cacgattgat cattgctgtt
     4861 tcgtacattt ttttcattga gatcatcctt tctttcgtcg ttctatatta agtgtaacga
     4921 gtatttttta atctgacaaa ggtaatgctt gcattcggcg acatcagtta gacaacatcg
     4981 atgatcagtg atagaagcag tttatctata caaaaaaaga agggttctat gatatttggt
     5041 gtccttactc gccttgagta acaacaccaa atatcataga accacttaat cagcttcaca
     5101 ctgctttttc tactttcgta gttgaaaaaa acttaaacaa atcatcggca aatagttaaa
     5161 gaaaaaactt aatcgttgaa agaagcccaa ttgcttaaag aaggcaaact gactaatcga
     5221 cggaatccgt gctaatccgt aaagacctgc aattagtaaa ctaataactg ttaaaacaag
     5281 ataaaaatgg ctaagcgtac cttgaccact ttgacgataa agcagaacaa gtaacaatgg
     5341 gaaaagtaga aagcctgcat agcctagccc agaacctata ttatggatcc aagtcgatag
     5401 attacaagag ctttcattcg tattgatact gaataagcca gtaaaaatac aatcacctat
     5461 cccatataaa ccaactgttg caacaacaag tattgcaagt gtttttgatg ttccaacaaa
     5521 taggtgatac aacgcaggca acgaaagaac aaaaaaaagt ccagatacaa ctgaccagac
     5581 caagaaagca cgtctgactg gactatctac gtcaccaaac acactaatta cggtagtcat
     5641 ttgattcagt ttgggataaa aaaggccaag gatatacggt gtcgataaat cactcatcac
     5701 acctaataat aaaaaataaa aaccatattt ttgcaaaaaa atcattttct tcccctactt
     5761 tttagtgatt attcgataca tccaacaatc aaattttttc tcattttaac acatattttt
     5821 attctagttg tcttttgaac aatcaataac ataaaggtga gtttcttcta cattttaaaa
     5881 aatcgaatgg cactgaagag ttcagttgtc agcatcaatc tcctactcaa aaaggcaaaa
     5941 aaacgtaagt cagatgttgt tgacatctca cttacgcatc cattgattga aaatttctta
     6001 gtaaaatcta ctagcctaaa aatttgaaga cttcttctcg atcatacagt ttaaatactt
     6061 tctcgcataa aaattgagta attagtgccg caaaaacagg gatgactaac caacaaagaa
     6121 caacaagaaa gccatttagc cctgcatcta aagaagccaa cggaccaaca agtccgacca
     6181 cgccgaaacc agcagaagca ggcgtacctg aaatagaaaa tagagcgaca ggaatagctg
     6241 taatcactgc actaactaaa caaggaataa gaatcacagg ttttctaaat agattaggca
     6301 tcatcatctt catagcgcct aaagcaatcg caattgtcac acctgactta ttaaccttcc
     6361 aagagttcac tactaaaaca aaagtggttg cagctacgcc catcgcagcc gcaccagcag
     6421 aaacaccatc tagttggatt gccattccga ttgctactgt tgaaatagga gagataatca
     6481 aaaaggcaaa ggaacaacca atcaagatag acattaacag cggttgtaag gtagtgaagt
     6541 tattaatcaa tgatccaatt gcagaagtaa ttgctgttac aaaagggaat aaataaaaac
     6601 caagtaaacc tgcacctaca cctacaacaa tcggtgttaa cacaatcgac actgacccaa
     6661 aactatttcc aatcagtaaa atcagcccga cagcaatcga tgctgtcagc atcgtattaa
     6721 taatatcgcc tgtaccagca ccaacgtaaa cacccgtttc acccaaatca ggtgtgaatt
     6781 tgactacacc agaaccaaca aaagaagctc cggctacaac catcattctc atcggatcaa
     6841 atccaaattg taaggcaatc aaaccaccaa tgatcaaagg tgttgctagt tgaaaaataa
     6901 ctgctaactg tgcgatcgtt accgcaaagg gatacgcact aaaatatttt aaaatggcac
     6961 ctaatactgc attaggaatc aatccaataa tgattcctgt tgctgtacca gcgaggactt
     7021 tattcagaaa aattttcggt gatatttttt gtgaagtttc cattcaatct ctcctttatt
     7081 ttacgttcaa actatcttct tttgcatgga caagctcagt caagaaatca caataaggcg
     7141 tcgcaacacc atatttcttc ccttttctag aaattgcgcc attgatataa tcgatttctg
     7201 ttaatcgatg gttcttaatc aagtcttgat acattgaagg ataatgtaac ccaattgttt
     7261 ccgggtcaaa acaagattca caatgtgcaa tgacttctgg gacatctagt tcaatcttct
     7321 ctactgctgc tactttggca aactcattga caatcgtcgc caccatttta tgagcagtcg
     7381 atgtttttcc tagctcagcc atattaacgt ctaagattgt gcatagtccg ttcattgttc
     7441 cgttcacaca tgctttgcga taaatagaat agtgaatatt gtcagaaaaa tgagcattta
     7501 atcctgattc agacaatttg tctgctaatt tttttgcagc tgcttctttt ccatcaccta
     7561 aattttgtaa ttctactgaa ccacttccaa ataatttgac ctgaccagga ccttcaagac
     7621 ctgccgtcca catggtattt ccaatataga tattttccat tggtacaaat ttctcaataa
     7681 tatcttcatg cccgatacca tttaatagac ataagacctc tgtatctttt ttgattaatg
     7741 attggatatc ctgcagcatt ttttccagct gcatcgcttt ggtaaataga ataatcagat
     7801 caacttgatc ttctttttct acttcggatt gaagaacgat tggtagtttt gcttctacct
     7861 ctttaccatt aaaatttgct tgtaatccat gttctttgat ttgttggaca tgttctgccc
     7921 agccatcgat taataatact tcgttcccac tttggtgaag catcaaccca aagcgacttc
     7981 ccattgcgcc agcgcctgca attgctattt tcattgattc ttcctccttt ttctttctat
     8041 tatactcatt tgagaatctt ttcacaacct cgttttgtta ttcttctctt atttatcatg
     8101 tttatatcca ccattcaagt tattttatca gcaaatcaat aaaaactgga atagaatccc
     8161 aatttcatcg taagagaaac tagactagca ataagaaaat agaaacattc atagaaaaaa
     8221 tctcactcct ctgattataa aagagggggc attaacctcg tgtatactaa aaccttccat
     8281 tcattcgatg gatgattttc tttttgtgaa aaaatattca ttgtagtacg atgttgcgca
     8341 acacagacgg atggtattgc ttattattta ttaaaatcga acaatacact tatttaaaaa
     8401 cttctttccc agattttctt c
//
LOCUS       DAFKHN010000102         8416 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFKHN010000102 DAFKHN010000000
VERSION     DAFKHN010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.102"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..1048)
                     /locus_tag="LY912_002514"
     CDS             complement(<1..1048)
                     /locus_tag="LY912_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBM6956156.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQL"
     gene            complement(1202..1732)
                     /locus_tag="LY912_002515"
     CDS             complement(1202..1732)
                     /locus_tag="LY912_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBM6956157.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(1831..2181)
                     /locus_tag="LY912_002516"
     CDS             complement(1831..2181)
                     /locus_tag="LY912_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBM6956158.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(2338..3867)
                     /gene="ahpF"
                     /locus_tag="LY912_002517"
     CDS             complement(2338..3867)
                     /gene="ahpF"
                     /locus_tag="LY912_002517"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBM6956159.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(3877..4440)
                     /gene="ahpC"
                     /locus_tag="LY912_002518"
     CDS             complement(3877..4440)
                     /gene="ahpC"
                     /locus_tag="LY912_002518"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBM6956160.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(4584..5246)
                     /locus_tag="LY912_002519"
     CDS             complement(4584..5246)
                     /locus_tag="LY912_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6956161.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            5430..7076
                     /locus_tag="LY912_002520"
     CDS             5430..7076
                     /locus_tag="LY912_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBM6956162.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7067..8149
                     /gene="uxuA"
                     /locus_tag="LY912_002521"
     CDS             7067..8149
                     /gene="uxuA"
                     /locus_tag="LY912_002521"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBM6956163.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(8257..>8416)
                     /locus_tag="LY912_002522"
     CDS             complement(8257..>8416)
                     /locus_tag="LY912_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HBM6956164.1"
                     /translation="QLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQS
                     KKENQVTS"
BASE COUNT         2757 a         1611 c         1511 g         2537 t
ORIGIN      
        1 tcaattgact ttgctgtcca atttgtaaaa tgatcaaagc catttctcca cgcgaaatca
       61 taccagcacc gaccatcaat gaactatgtt gagaaaaacc ggcaatctga gcaccaaaat
      121 aacctccaag caatttggtc aaaatcgcta caagcgtcaa tatagaaata aagagtagtt
      181 gttcactaaa gtcagaaaaa tcaacttcta atcctacact gacaaaaaat actggtataa
      241 atactgcata tcctaaagcc tctacattgt ggtatacttc ttctttaacc tttgtctgac
      301 tgacagctat cccagcaaaa aaagcaccaa tgacagagct aagcccaaca agatccgcta
      361 cgtaagacat tcctaaacaa ataactagcg atacgatgat aatagaagaa tttgcgtaca
      421 ctttttctgc aaatgaaagt aggaaaggcg caatccattt gactaataag aaaataaaaa
      481 caaaataaat tagctgttca atcaaaacaa gcggtaaaga agcattgcta gaagcttccc
      541 ccgttagaaa agataggctg aaacttagaa ctaaaacgac taaaatgtca tctaccacag
      601 aagcacccaa aattgttgat ccttcttttg tattcactac gtttagttct tttaatactt
      661 ctactgaaat actgacagaa gttgccgcaa gaataatccc aaagaaaatc gcttcatttc
      721 ccgaaacttg gaatgctttg cctgtcaacc agccaaaaac aaccgggaag atgatcccaa
      781 gcaaagcaac gaacatacca ggtcggaaat attttttcaa aagagataaa tcactttcca
      841 gaccagctaa aaacattaat aagatcacac caatctccga aaagtcatgg actagaatat
      901 caggtttgac ccaattcaat ccagcttggc ctagcaaaac accaacaagt aattgtccaa
      961 tcactgctgg gatacctaat ctccgcgaga tatgtgagcc aatcgttgtt gaaatcaata
     1021 tcaggcataa aataccaata aattccattc tcatcattcc tttgtataaa atatagcccg
     1081 aacttagcat aacatacatt attgaaaaaa taggaaaata tactcacaaa aaaaccaaca
     1141 atccaaaaga tttttttgga ttgttggttt ttatacggtc tattttaata actaaaaatg
     1201 attaacgtat agtcattttt cttattctga tgaaattgat aatctcctgg atgcccatga
     1261 aaatcaaaat aaagccgaat atttggaata gaagcatcaa acttttgaat ggattgaaca
     1321 ataagacgaa tccgccaatc aacaacagaa tactactata aacactccaa cttttagctt
     1381 ttgtattcat gctgaagaac aactggaaca agctgttgat gataacagct aatccaagaa
     1441 gaatcggcag gatagaaacg attgcaggtg caaaagcata gacgatcaga gctaagatca
     1501 ggaaaaaaag accactgaac agaccgatac tccaagaacc tgttttcctt ttaaaacggt
     1561 aagcctcaaa aagattcaac aacccaagca aaacaagata ggcggtgatc agataaccga
     1621 taaaatgaaa aacagcagaa gggtttagca caatcgcaat cccagaaata atataaacag
     1681 cagctcttaa taaggcgtat ttttgaatat tttgtttaat cgtctcaaac atataagaaa
     1741 acctcctttg acttatttta acgtgaacta gtcattttac caaattaaat gttacaaaat
     1801 gagcgaagga gaagaatatc tctggaaaaa tcaacttctg aggatctttt ccattttttt
     1861 gccttttgct agctcatcga tcattttatc taaataacga atttctttca tcaagttatc
     1921 ctcgatgtct tctactcgta caccacaaac aacacctgta atcaaggaac gtgaaggatt
     1981 ggggacaggg gcttccgcaa aaaattgttc gaaagtcact tgtttttgta gttgatattc
     2041 tagttctgtt tgggaataac ccgtcagcca acaaatgatt tcatctactt cctcttttat
     2101 acgatctttt ctctccgctt ttgctacata cataggataa acgcttgcaa aacttgtcgt
     2161 aaaaatacga ttttgcgcca taatcagtca cctttctttt tttcaaatta tttactactt
     2221 atagtatata agaaaaagag aagaaaaagc gattattcaa aaaaacaaaa aggatggtga
     2281 caaaattctt gtcaccatcc ttttttccgc tctctgactt tttacaatct tcatagctca
     2341 agtgcgcatc agataatcga atgctcctaa agctgcagta gctcctgaac ccattgaaac
     2401 aatgatttgt ttgtatggac tatctgtaca atcaccagct gcgaaaacgc cggggatatt
     2461 cgttgcgcca tttttctcgg tcactatttc atttcttgga ttcatttcga tcgttccatc
     2521 tagccaatcc gtattaggga gtaagccgac tagaatgaat actcctgaaa cagctagtgt
     2581 atgcatctcc atcgtacggc gatcgatata ggagagagat tctacctgat tcgtaccgct
     2641 gatttctttc gtcgctgcat gtttgataac agtgacattc gcaagagaga ctagtttatc
     2701 ctgtaagatt tgatctgctt ttaattctgg taagaattct agaacatata catgttttgc
     2761 taacccagcc aaatcgattg ctgcttcaac accagaatta ccaccaccga taacagcaat
     2821 ctcttttcct ttaaataaag ggccgtcaca gtgtgggcaa taagcaattc ctttattttt
     2881 aaactctttt tcacctggta cattgataga acgccagtgc gcacctgtcg cgatgatggc
     2941 ggtttttgct ttaagtgata taccgttagc taagccaata ttaataaaat gttgctcttt
     3001 atttaaggaa acggcctgtt gattcatcat aatgtcgata gggtaactac gcacatgact
     3061 ttctacttgc tgcatcaatt ttggaccttc tgtgtaagag gtaccaatca tattttcaat
     3121 ccctagtgtt tcaacgactt gtccgccgaa agaatcagcg acaagtcctg tacggattcc
     3181 tttacgtgct gcatagatag ctgcactact agctgctggt ccaccgccaa tcactaatac
     3241 atcataaggt tctttttcaa acaactcttc ttcaatcaaa gggccagtga ttttttcaac
     3301 aatttgttcg atcgtcatgc gtccgctact aaattcttct ccatttaaaa acacagttgg
     3361 cactgccatg atttttttat catcgatttc tttttggaac atcccacctt caatcatcgt
     3421 atgagtaata tttggattta atacagctaa tatattcaat gcctgtacaa cgtcggggca
     3481 attatgacaa gtcaagctaa cataactgtc aaaatgcaat gtttgtgtta tttttttgat
     3541 tttaagactc aaagattcac tgattttcgg tgcccgtcca ctaatttgta acatagccag
     3601 taaaaaagag gaaaattcat gaccgagggg gataccagca aaaacgattc cactttcttt
     3661 gccaactgga ttgatagaaa aactaggtgt gcgcatcgaa tctctttttt cccaagagat
     3721 tttaggagac atttctgcta tttccttcgt aaattcagct agtttttgac tattttcact
     3781 attatccaaa ctaacagaaa aaacaatagg agattcaatc agtgctaaat attgttcgag
     3841 attttgttta gtttctttgt ctaacatatc caccacctaa atctttccaa caagatcaaa
     3901 acttggtttc aatgtttcgc cactttcttt ccattttgcc ggacaaactt cacctgggtg
     3961 ggtacgtaca tattgagcag cgcgaatctt atcaatcagt gcactagcgt cacgaccgat
     4021 tccatctgca ttgatttcca tagcttgaac gattccgtct ggatcaataa taaatgttcc
     4081 tcgctgagct aatccttgct cttcatccaa aacatcaaaa atacgagaaa tctgatgaga
     4141 cggatcaccg atcatcacgt attcgatttt accgatagca tctgatgtat catgccatgc
     4201 tttgtgagta aagtgggtat cggtagagca agaaaagact tcaacaccta aagatttcaa
     4261 tgtactgtat tgttcttgta agtcttctaa ttcagtagga caaacaaaag taaaatcagc
     4321 tggatagaag caaagaatac tccagttccc cataagatct ttttcactga cttctaaaaa
     4381 ttctccttga tgataagcat gtgcattaaa ttcttcgatt tttttcccaa tcaatgacat
     4441 agtaaaacct ccaataataa ttatttattt ataattattg taatttagtt ggagttgcaa
     4501 agtcaatgga tattttgtta tttaataaag attactcaaa aacgaaggtt aattataaaa
     4561 atagaagagg tcgcaagaaa atgctactgc tggaaatact cgggataacg ttgagtaaca
     4621 gtttcctgtt ctttcagcat catgtgtaag tgcaatcccg tttgaaatcg agcttcttct
     4681 ggttttttat caactaaagc cttgagtaaa tcataatgtt gttccatgat cgtttcccat
     4741 ggaagcccct gaatggtcac tcgtaaccag cggaaacgtt ctaaatgggt attatggtca
     4801 tctaaccagt tccaaacttc ttttcttcct gcaatttcga aacaagcttc atgaaataaa
     4861 ttatctgcac ggaaaaaagc gcgttcgtca tttattttga ctgctttttc ttgttcttct
     4921 aaaatcgttt ctagcactat tcgtgtttgt gtgtccaatt tggaacaaca ttcaatcatg
     4981 atttgctctt ccaactgttc tcggacaaag cgagcatttt ctgcagaaac aagattaatt
     5041 ttggaaacat acgtaccact ttgaggtatc gtatacacga gttcttgctg acgtagttga
     5101 atcaatgctt cgcgaatggg agtccggccg atagcaagat gttcctccag tgccttttca
     5161 gatattttcc ttccaggttc taagtcagca tagataattt gtttacgaat cgcttgataa
     5221 gcttgtgatt gcaagctgct tttcatcttt attcctccaa aatcatttct atgaacgtag
     5281 tataacagaa gaggtctgaa aaacaatctg gtatgtcaca ttaactagta aatttgtata
     5341 aatagtaaaa ttttggttga catagcgatt tttattgcat aaaattcact tgaatacaaa
     5401 aactaatatg ttagtttagg aggggaaaaa tgattgattt aaacaactgg aggaacttta
     5461 tccctgaatt atctcaaaaa gaagtagaaa tacctcattt tgaccgtgca tcattaagag
     5521 aaaatggaca aaaaaatcct gtctggatcc atttcggtgg cggaaatctt tatcgaggat
     5581 ttcatgcaga aatcgctcaa cgtttagcgg atctaggcga attgtccact ggtgtcattg
     5641 tttgtgaaac attcgatgaa gaaataattg aaagggctta ccaagatttt gatgatttga
     5701 ttcttgaagt ggtcatgcca agcagtggag agttcgtcaa acgtatatta gctgcgacag
     5761 ctgacagtct gtattgtcat ccagattgtt ctgaacactt tgataagatg attcgacact
     5821 ttgaaaatcc tagtttacaa ttagttactt ttgctattac tgaaaaaggt tatcgattga
     5881 aagatacaaa taataaatat ataggaccga ttgcagtcga tataaaaaat ggtccaaaga
     5941 agccatcaca tacaatgagt attcttgctg tgctacttta taaacgtttt ttatctggag
     6001 cttggccgat tgcacttgtc tctacagata atttttcaca aaacggtagt caattacgta
     6061 cttctttgct aacgatcgca aaagaatggc aaaaggaagg ttatgtacaa aatacattta
     6121 tccaatactt atcgaatgaa gaaattgttg cgtttccatg gacgatgatt gatcgtatca
     6181 ccccgaatcc ttccttgtca gttagcaaaa tgttggcaaa agagggcttt tcaaatatgt
     6241 cgattttcca aaccgcaaaa ggaaataata ttgctccatt tgtcaataca gaggacatcc
     6301 attatttaat catggaagat cattttccca atggacgtcc gaaattcgaa aaagctgggg
     6361 tattcttgac tgatcgtgca acggtagata aagcagatac gatgaaggtg acgacttgcc
     6421 ttaatccttt gcatacgtct ttagctatta tgggttgttt actggggtat aggagcatag
     6481 ctgaggagat gaaagatcca gatttatcgc tgctagtttc tgaaatcggg tacaatgaag
     6541 gcctcccagt tgtggagtct ccaggtatca ttgatccaaa gatctttctg gaagaagtaa
     6601 ttactgtgcg cttttctaat ccaaatattc ctaatatgcc tcagcgaatc gccacggata
     6661 cctctcaaaa ggtggcgatt cgttatggtg agacgattaa aaaatatatg gaaatagaag
     6721 ttaaagaccc gcagacactt gtattcatac cattgactct cgctgcttgg cttcgatacc
     6781 ttattggcat tgatgatcaa ggaaaaccat tcatcccgag tccagaccca ctattgacag
     6841 accttcagca taagctttcc gatattcaac tgggtacgca agatacatca catattcatg
     6901 agaaaatggc tcctattttg tcaaataaag aaatttttgg tgtagatctt taccaagcag
     6961 agcttggcag aaaaatagaa gaaatgttca tcaagatggt agcaggacca aatgccgtac
     7021 gaaaaacatt acaggattac ttacaagaac atggaggaaa tttatcatgg aaatgacttt
     7081 tagatggtac ggatcacagg aagaaaagat taccttagat gaaatcagac agattcctgc
     7141 ggtcaaaggg attgtaggca cattgatgga tataccagta ggagaggtat ggcctaggga
     7201 gaggatcaaa gaactaaaag aagaaattga gtctcgtggg ttaacactaa aagtaattga
     7261 aagcgtcaat gtgcatgatg ccattaaaat tggattacct tcccgtgagc agtatatcga
     7321 aaactataag cagacaatcc gaaacttggc agaatatgga atagaagtca tctgctataa
     7381 ttttatgcct gtatttgact gggtgaaatc tgaccttgac taccgcttag aagacggctc
     7441 atccacgtta gcttttatat ctgatgatat tccagatgat ccaagagaaa tcgtcgcgcg
     7501 catcgaacat tccagcaatg aatttggatt gccgggatgg gaacctgagc gcttagctcc
     7561 tatcaaatcc ttgcttgaag cctatgcatc agtagacgaa gaaaaacttc gagaaaattt
     7621 tgcctatttt ctccaatcaa tcatcccaac atgtgaagag gtaggggtca aaatggctgt
     7681 acatccagat gatccgccat actcgatttt tggattagct cgaatcgtaa agaatcgaga
     7741 agatttagat tggttgtgtc gcatagtaga cagcccttat aacggaatca ctctttgtac
     7801 agggagtatt gcagaagatc cagaaaatga tgtatatggg attttagcag aattttgcca
     7861 aagagatcga atcccatttg cacatgttcg aaatattaaa tttttagcta atcgagattt
     7921 ctatgaggca ccacataaat ccgaatacgg ttcattagac atgtaccgca tactaaaaac
     7981 aatgtatgac aacggattta acggatacat ccgtcctgat catggaagaa tgatctggaa
     8041 tgagacagga agaccaggat acggcttata tgatcgagca ttaggtgctg tttatctaaa
     8101 tggattatgg gaagcaatcg aaaaaggaaa caaaagtaaa gataattagt gaaaaaaact
     8161 gtaattttat tatgtaaata agaaggatgt tcaaattctt gatacataaa tccggaggtt
     8221 gttaataagc attcggattt atgtatctta tttggtctag gaagtaactt gattttcttt
     8281 tttcgattga tccatgagtg cttcttcttt taattcaaag atatattctg agatcctcat
     8341 aatcactttt ttccagtctt ctggtgtgat gattcctttt aaaatataga tttttttgat
     8401 atgagaaggc aattgt
//
LOCUS       DAFKHN010000103         8362 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFKHN010000103 DAFKHN010000000
VERSION     DAFKHN010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.103"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..317)
                     /locus_tag="LY912_002523"
     CDS             complement(<1..317)
                     /locus_tag="LY912_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956165.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIF"
     gene            complement(368..1996)
                     /locus_tag="LY912_002524"
     CDS             complement(368..1996)
                     /locus_tag="LY912_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956166.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVIFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            complement(2016..2219)
                     /locus_tag="LY912_002525"
     CDS             complement(2016..2219)
                     /locus_tag="LY912_002525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956167.1"
                     /translation="MSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNA
                     YIARLKRFIDKYKENSDKFSKDK"
     gene            complement(2220..2909)
                     /locus_tag="LY912_002526"
     CDS             complement(2220..2909)
                     /locus_tag="LY912_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HBM6956168.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            complement(3164..3484)
                     /locus_tag="LY912_002527"
     CDS             complement(3164..3484)
                     /locus_tag="LY912_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956169.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            complement(3517..4635)
                     /locus_tag="LY912_002528"
     CDS             complement(3517..4635)
                     /locus_tag="LY912_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956170.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLRTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            complement(4664..5458)
                     /locus_tag="LY912_002529"
     CDS             complement(4664..5458)
                     /locus_tag="LY912_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956171.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            complement(5468..6343)
                     /locus_tag="LY912_002530"
     CDS             complement(5468..6343)
                     /locus_tag="LY912_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956172.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            complement(6560..6817)
                     /locus_tag="LY912_002531"
     CDS             complement(6560..6817)
                     /locus_tag="LY912_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956173.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            complement(6820..7044)
                     /locus_tag="LY912_002532"
     CDS             complement(6820..7044)
                     /locus_tag="LY912_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956174.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            complement(7217..8260)
                     /locus_tag="LY912_002533"
     CDS             complement(7217..8260)
                     /locus_tag="LY912_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBM6956175.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
BASE COUNT         2379 a         1706 c         1038 g         3239 t
ORIGIN      
        1 atgaaaatat aaaaaaacca aataaatgaa gggattaacc aagcaaaaat ttctaatatc
       61 acattaaatc ttttcatttt tccaaaacta ctaagacttg atactaattc aatcaaaagc
      121 ttatcgctac ttgctgattc atcatattta gttcctagat tatctaaact tagcatataa
      181 gaaatttttt cctgatctgt tagttttgaa aatgaacttt cttttaaact ttggattata
      241 caatcagcac taaatatttc gtttaataaa gcagttttct tttctaattc cttagaagat
      301 aaagttagtt ctctcatagt gacttaccta ctttccaaat tttgtgtcct atttatcact
      361 tctctcttta tataagtgat aaaagatcgt aaatacgttt aattgttaag ttcatattca
      421 catgattatc caaataaaat atcttatctt tattagaaat ttcactcata acacgataat
      481 atagaccatg attcaagtaa tctgtatata gaaaaatcgc atcacacgta ttcaaatttt
      541 taagtatctt tccattattt tcgcttacat caaacatttt aatatttggt aatagttcag
      601 ttaatttatt ttgaaaaatt acatgtcctc ccactaaaag aatgttttta tgttttagat
      661 aagctatcat ttcagacagt gaaggctctt cagttttacc atttaatgat tgtctatgtt
      721 cttgctcctg caattgcttt aatactttat tttcaaacct cagctgttca agttcttttc
      781 tgattccttt taattcttta atctcttgct tcaaaagttc ctcttctttt tttgccgatt
      841 tgactaaaga ttctaaccga ccgttttctt tactcgcaat acttaattct tttcttaatt
      901 tgattacttc agatttgttt tcttttctaa tacttgcaat ttgttttgct atttcataat
      961 cagaattcag gatcaattct tccttagcat ttttaaacaa ccgagttaaa acgaactgat
     1021 ataacaaact ataaaaaact agcaaatagt caatttgtcg gtactcggta ttctgatcaa
     1081 ttgcatatag agagattaaa acgaaataca caatatcatt cagctcgcta cccttgatct
     1141 caaaattatt gactaagtaa ctatcaatac ccatcaaatc tgcaaaatct ccatacaaag
     1201 aaaaatatga ttttgacaat atatctatat ctgaatcgtc aaacccattt actattttcc
     1261 catcattgtt agtagttgct aacgaagcaa tagtgacttt tgaattgggt tttacaaatc
     1321 ctatacctaa tagttctttc atctttttaa tttcaagttt gttatccttt tgttcggctt
     1381 tatgctgttt catattgtaa agcggataaa atgctgttcc gtaagcacct tttagtacgt
     1441 tatctataaa ataatcttca gaacctgttt tgaatagaaa gttaatcgca gccaaattag
     1501 ataacagctc ttcagtgttg tgcatcaatt ttttatcatt taataaatta tccccaagat
     1561 atttcattgc ataataaggg tttgtttcgc tacttatttt taatattttt tgatagctat
     1621 tcctcacgat attaaccaaa atatctgtct gattaattga attacagtac aaagccactc
     1681 ctaatgccat ataaacattc aaatcatgtt ttgccgtacc gttgaataaa acgtcttcaa
     1741 cttttgaatt atctcgtcta tactttttga tcatattttt gatattttga tcattctctt
     1801 ggtatatttt tttcactcgt tccaatgcct tgggtttgtt ggaaacagca acagcgaagt
     1861 ctagttcttt gaaatcaata tttagtatct gtacctcatc acctagatta taatctctat
     1921 ttacgctcgg aaaactgctg aaatctaact gttttttacc tatttttggc gaaaatattc
     1981 cttcgatttc tggcaaatgt aatcacactc tctccttatt tatctttaga aaatttgtca
     2041 ctattctcct tatatttatc aataaacctt tttaatcgag caatataagc gttaaccctt
     2101 ttaggttctt cttttcgcca ttcatcgttt acgtgaccat tttcaaagaa agaagctaaa
     2161 agagtttcca cttcattaac catatctgcg atcgtatatt tttctgtacc ctcactcaat
     2221 tattcatgaa ctgttaagtg ttcatagcta agttcattca taattttgtt atagcgtttt
     2281 cttgcttttt caaattcttt ctgttcgtca aattccactt gattcttcat gttgttcttc
     2341 ctctctgttt gatatttttt cacttcttca agtttagcat ctagttccgc tttaacttct
     2401 gtcacttctt taagcgcttg ggataactta tgagacaatt tcgcataagt ttctctcttg
     2461 tattcatttc ctactcccaa ctcttcggag tagaactctt ctagtagtct tgcaaaatta
     2521 acatttctcc tgccagcata gttttttagc ttctcaaaat cagattgaaa gacagcaaca
     2581 cttttgtaat ccttttcacc ctcaaaatca aaagcatagt catactttcc tgaaatcaat
     2641 tcatcaataa ctgtagcaat atattgagag atagaaatat tatcttcact tctatgtcgc
     2701 tctataagat tatatatatc agggctgaca tgaaacgtac ttctcttttt tgtttgcctt
     2761 tttctaactg ttacgaccac ttttggaact tcactatctc cattgatctc tttgtatttt
     2821 tcaataaata attttctagc ttgttctcga ctttttgccg gaatttcatc tacaatttta
     2881 tcttctaaat aaatatagtg tgttctcata cattcgtcct ctatcttctt tactctcaat
     2941 cttcatgatc ttagttctta ccttgtttac tcttaaacat tgcaaaaaaa tctagtcaaa
     3001 atcaaacttg aaatcatcgt ctatcacaac acccttaact tcatctttag atttcccaaa
     3061 ggaaccctta ttttcaaatc ctttattttt gaatgatgat ggttatggaa aacttccttt
     3121 gaaattctga caagcataac tagtcagaac tgttttactt agattaagct ttcaaaagat
     3181 actgatgaag aactaagttc tcagtacctt cccattcttc aataaaaaat atttctcctt
     3241 cttttaccca ctctatagct aatttcttat aatcaaataa accatatgtg tttaagcctt
     3301 tgtctttcat taaactcaaa aactgatccc cttttaatct ttctgtatca tccatcagaa
     3361 attcaactaa atctttatcc atgcgtgcaa ctttttcgtc ttttagtgcc attgatttag
     3421 catagtcagt tgaatctttt agaataataa cacctacatt tccttccaca attttcttct
     3481 tcatatttac ctcctaccat cttttccaaa gagtatttag tcaaaatcaa actcgaaatc
     3541 atcgtctatc acaacaccct taacttcatc tttagatttc ccaaaggagc ccttattttc
     3601 aaatcctttg tttttaaatt ctaaagcttt ttcgacttct tctttggata ttgtatgaac
     3661 ttttttctta actactccaa gtttatacag ctcttcaaac tctggtactt cggatctgaa
     3721 atacaatcca tcagtacgaa tttttaatag cccatatgcg ctatgaacgt atttctgttc
     3781 atatctaacc atacgatctc taaatacgcc tgctaccatg gaggaatacg ctcgattata
     3841 catactgtat ttatcgaagg tgcttgtttc tccttctctt aatgattttt gtccgatagc
     3901 accaaatact ttcgttctaa gatttttata aagcttcaac gtatcaggat cagtttttaa
     3961 tggctcgatt ctttcaaaat attctttgag taatcctttt ttcgtcaaaa atgtgtggct
     4021 atctaggact tccatctctt taatatcata ataatcaagg ataagtgtta gctcaatctc
     4081 cgataaccaa ataggctcat tagctgtttt gggattttcg ccataatccg caaacatcga
     4141 ctgtgatttt ggattagcat atgttccttc tttggctgtt ccttcaaaat taaccaaaaa
     4201 gaacatatac gttcttaaat tttcatacgg tcttactttt ggtctattta tcgctctcaa
     4261 aatagcttga tctgtattat attttgcttt caaataagtg tttgacggca aaggataatt
     4321 tctcatgatc ctcgaatagg cttcgttgaa atcatattcg atcatctttg ctccttcctc
     4381 aaacaaatcc aagttataca tgctaccgga ggtactggct ctataggctg aacttggaac
     4441 aaagaaaggt gcatcttccg gcttatcata gcccaaaaaa tgtattcctg tttgcttgtt
     4501 ctgacggtaa atgtccatca aaagatattt gatcgtacta aaagaatcta attttcctct
     4561 tgtcatccac cctaatccga caagtctttt aattttattc tgcatttcag gtgtgtatat
     4621 gctattgttt cccatttatc tgctcatctc cggctttttt attctagacc ctatatttgt
     4681 tcattacacc acttatctcg tctacaaagg ctcccagatc gtgtgtaaag gcatcatagt
     4741 aatcttcaat ctcactcgat tcagttctcc ggtttcttcc gtttttattt ctgaatagat
     4801 acatctgcgt ttctcttaaa tcccttgctt ttttcgcaag tgctaataaa tccgtaaaat
     4861 tatcaataac cataatgtca ttgatcataa aaccttcttc atgaccatac ttttcagcca
     4921 tctcgataaa atcattaaca tcgaacaact ccaataattc tgctttatat ttctctaaca
     4981 atgtatttaa atagcgattt ctcaattccc atgaactttc accagttccg tattcaacct
     5041 tgatccctaa attcttagtg tagccttttg ctgtgtatcg tccaatgaag tctcccttat
     5101 tccgattgct atcttcttct ttgaaaaact cacgccaaat cccctttttc ttcttaggaa
     5161 ttagacctct gctcttgaaa tcatcatatt tttttgaagc ttctcttcgt gtatctaagt
     5221 acctttgctt cagctctgta gctgattcat tcgttccata ttcaacagtg atccttaagc
     5281 gcctgctata accttttgct gtatatcgtc caacaaagtc accgccactt cgatcactac
     5341 tgacttcctt aacaaattct ctccatatac cttttttgtc ctttggtatt aatcctcgtc
     5401 ttttcatatc ttgatatttt tcagaagctt cttttagagt attctttttt gctaccatat
     5461 tttccactca ctctttgtta tctagtattt taataactgg tttcattttt gtaatatctt
     5521 ctttttcagc tatatacaac tccgttacgg taacgatctt agtatgattt agattaatta
     5581 ctttcacttg atcgccaatt ttgatttttc ctcgcaaccg tttgggaata aaccagttgt
     5641 ataatcgtga tttattatta tctacataag cttttattgc attttcagga aacaggttat
     5701 ttagtctttc aattttttta cttttaaaaa attcattcgc aaacttttca tcaacaacta
     5761 aattaaataa agtttcagaa tttacagctt ccatatctat tcctttgtag ataggagaaa
     5821 gcaatttttt atattttgcc agtaatgact ttccagaatt actaatctta atttggttac
     5881 ttaaatcttc ttgataaaga accccatatc gaagtaacgc cttaatataa tgttttaata
     5941 tgccgttgat accagaataa atatccatgc cgttctcaat atagtagaaa gtgtcgtctc
     6001 tccaaaacaa tttgaagcta ttattcaaat aaagtaacaa gatcaatata tgtttgtcag
     6061 aaattctgac aaatctatta ctttttagat actcaccaat ggcttcactt aactctttga
     6121 agccattgta ttttcccgat aaaaatgtcg taacattatc ttctctcttt ttcctatggt
     6181 gtgaacttac cctgaaataa tagagtctat tctcatttaa tattgaaaaa taaatacttt
     6241 cagttgtttg tgagcattgt atatagttga aatgatatcc atctggcatg acttttttaa
     6301 ctgtattttg tactagctct gaccaccttt tgttagtagt catatatttt tttccattaa
     6361 accaaacata aatatctttt ttaaaaattt tgttcccccc ctattgcgtt ttctttgaca
     6421 ttaaagccct ttgttttcat cacattcgta tagccctagc cactcataac ctgatgcttt
     6481 tgcgaagttt atttaaaagt gttttccttt gtaatctacc tttcccctcg tcctggtact
     6541 tttcttggcg actattaaac tattcaactt ttttagaatc attgtcagct tgaaatcctt
     6601 cacgtttcat tatgtcttct gcttttccaa tgctgattcc tttccaatca cgccatccta
     6661 cgcttccctt attttgacga taggctttaa tagctgattc ggatatttgc catcttgtag
     6721 ccaactcttt ggctgtgtac ttatttgaaa aaagtagctt ctctatcagt gaaatatcaa
     6781 tcattttatt ctcactcctg aaatcttcat taatcatctc tagctagcta tatcttcaat
     6841 caattctaat atgtcggata aaccatcaac agcttcttca agttgatcaa cggattcttc
     6901 tgctttttca tatctttctg atccctgtag atttttaggt atattttctt tgtactcttc
     6961 ttcttgaatt acttctaact catcctttag ctcggaaagt cgctcgctta tttcttctaa
     7021 cctttttctt cttctttggt tcatcaaaat cacctcttcg cataatctct acgattttaa
     7081 tataccactt ttgtgtacta cattcaatat tttttgttat agattcgtat tacaaaaatt
     7141 tcctctaaaa aaataagagc ctatttacca tttcagtaat taagctctta tttcatttag
     7201 ttgataattc tatcaattaa cgtacagcaa ccgccattcc agtcacatta aatgctctct
     7261 catacgtgct tgcattgatc cattttgcgc caaatacagg gtcaacaaca tggtatgcac
     7321 catttctgaa gccatccacg agaactacat gtccattcca tactgcacga ccccaaggca
     7381 tttgtttgaa ctctggcgta gcatagttat aagtaatcca agttacaacc ggattaccat
     7441 tgcgaatttc attcttgatt ccattcgttc ctgaaccagt gatattgacg gcattaccgc
     7501 caacgttttt tgcccattta actactgggt cagccatcat gccttgatac gttccattaa
     7561 cgttatgacg ccactctcct gagtaaccat gataaggatt attgtcatta gcttttggca
     7621 tatagtttac aaaactggtt aagctttgat ttgtggctac acctttgtag tgtaaacctt
     7681 ctaataaaga agctccttcg cataacattg tatttccttg ccatacaaca ggaacgttca
     7741 acactttttc agtgcttgga gcaggtgtag gatttggtac gctgtttggc attgcatacc
     7801 agcctgtacc ttcaatcttc caaccttgtt tactaattac gttcttttca ttttgatcta
     7861 acgtgtagtg atgccaattc acgtatttgt tatataaacg tgttacagga actctatttg
     7921 ctccgttgta ggaatagaac gcaacacctt cgtacgtcca tcctgtgtgt gaaatcttat
     7981 ctctttctcc ggcatcaact gtgtaaaaat gttcaccgtt ataccgatta tacaaacgat
     8041 aaacaggagt accacttgtt ggagcttgcc atgcgacacc ttcgtaatgc catccataac
     8101 gtttcagatt gtctctttct ccaacgcttc tagtgtatag atgctctccg ctattgggat
     8161 tatacatacg atacatggaa atagagcttt ctgctgaaac tgaaggtgat aataatacta
     8221 gccccattgt gaatagaatt cctactaaaa attttttcat ttgattttac cccttttcat
     8281 tttttattgt cattattgca tgaaaattat tcgtaagatt gccaattaca taaacgattg
     8341 ttttaagatc ataatcgttg tt
//
LOCUS       DAFKHN010000104         8071 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFKHN010000104 DAFKHN010000000
VERSION     DAFKHN010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.104"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            261..503
                     /locus_tag="LY912_002534"
     CDS             261..503
                     /locus_tag="LY912_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBM6956176.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            854..1108
                     /locus_tag="LY912_002535"
     CDS             854..1108
                     /locus_tag="LY912_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HBM6956177.1"
                     /translation="MLELSKQLPVSDPRHFDYEEIAIKILEELQKNYTTKRVNGSNGL
                     LLHAVYDKNSLKGVDECVIWGDYFYVEGITRLAKTWYCYW"
     gene            1137..2396
                     /locus_tag="LY912_002536"
     CDS             1137..2396
                     /locus_tag="LY912_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBM6956178.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            2449..3345
                     /locus_tag="LY912_002537"
     CDS             2449..3345
                     /locus_tag="LY912_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBM6956179.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            3356..4225
                     /locus_tag="LY912_002538"
     CDS             3356..4225
                     /locus_tag="LY912_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBM6956180.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            4235..4910
                     /locus_tag="LY912_002539"
                     /pseudo
     CDS             4235..4910
                     /locus_tag="LY912_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            5116..6780
                     /gene="alsS"
                     /locus_tag="LY912_002540"
     CDS             5116..6780
                     /gene="alsS"
                     /locus_tag="LY912_002540"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBM6956181.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            6793..7503
                     /gene="budA"
                     /locus_tag="LY912_002541"
     CDS             6793..7503
                     /gene="budA"
                     /locus_tag="LY912_002541"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBM6956182.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            7633..>8071
                     /locus_tag="LY912_002542"
     CDS             7633..>8071
                     /locus_tag="LY912_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBM6956183.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEK"
BASE COUNT         2629 a         1270 c         1717 g         2455 t
ORIGIN      
        1 ttcttagcat gtaatttgaa caccctgatc cagttttttt ctttaattat tggtagggga
       61 gaataatgga ttagaataaa tctacctata agtagtagta aaaaaaagag cactatgata
      121 atatctttct taagagtaac cgctttaata aaaaatccag aatattctaa cataaatgga
      181 gtattcttag aatcaaaagg agaaagaaga tggtttatac ttatacggag caagaaaaaa
      241 tgaaagtttg agacacattc atgaatgatg gaaaagtaaa acaagtacca agttcaacaa
      301 aaaagaaaaa catcctattg aaagaagtct tgaaacgctt tgaccatgga gtgacttata
      361 cagaaacaga ggttaattcg atactgctga acgtattttc tagtggcgat tatgtcgaac
      421 aaagacgtta tctaatcaca tttggctttt tcaaaagaag ttcagacggt cgggcatatc
      481 agatgatggg aattgaaaat tagaagtttt aatttatact cattgaaaaa agttcaagta
      541 tgcgatattg gttctacacc gcatacttga actttttttg tcatctgtat ctataataca
      601 aagccaagaa cgttattcaa aatatggata gctatgataa aagctaatga gcgattcgca
      661 gttaaataag caatcgtcag taaaatcgtt ccaggagcgt acatgaaaaa atcaattgga
      721 tgcgttacat gaataaagat aattctcttt tatttgtacg aataaatacc aaaacgtacc
      781 tcctaaaatt agattcaaag aagatagcaa agaggaaaaa gatagttctg cagcagctat
      841 agcggcatgt ggattgctag aactttccaa acaactgcct gtttcagatc ctcgtcattt
      901 cgattacgaa gagatagcaa tcaaaatctt ggaagaatta cagaaaaact atacaacgaa
      961 acgagttaac ggatcaaacg gtctgcttct ccatgccgtt tatgataaaa acagcttaaa
     1021 aggtgtagat gaatgtgtga tctggggcga ttacttttat gtagaaggaa tcactcgtct
     1081 agctaaaaca tggtactgtt actggtgatg tataagagaa gaggaggatt catataatga
     1141 agcgatggaa aaaaatgatg attggatcaa tagttttagg aatgtcactc gtatttggtg
     1201 cttgtggtaa tcaagaagac agtagtgaag aatcagcaaa tgaaattacc gtttcgacat
     1261 ggaattatga aacaacacct gaattcaaag cgctctttga agcattcgaa aagaaaacgg
     1321 gaatcaaagt gaaagcagta gatattgctt cagatgatta tgatacgaaa ctcaccacga
     1381 tgctttcttc tggagacacg acagatgtat tgacgatgaa aaatcttttg tcgtattcaa
     1441 attatgcttt acgagatcag ttagtcgatc aaacagaacg aattagagaa ttagacactg
     1501 atgctgctga agaaacatat gaaatgtatg atatcgatgg aaaaacatat gcattgccat
     1561 atcgaacgga cttttgggta ctatattaca ataagaaaat gtttgatgat gcaggaatcg
     1621 aatatccaaa aaatctaact tgggacgaat atgaagattt agcaaaaaaa cttagtaaaa
     1681 atgacggaca agtttacgga gcatatcaac atatctggcg ttcgacaatc caagctattg
     1741 cagctgctca aaacgaggcg aatcttgttg aaccagatta tcaatatatg actgattatt
     1801 atgatcgagc attgaggatg caaaaagaag gcgcgcagat ggattttggc acggctaaat
     1861 caacgaaagt aacctatcag tctcaatttg aagaacaaaa agcagcaatg atgtacatgg
     1921 gaacttggta tatggctggc atactcgcaa acaaagaagc aagtaagaca gaagtagaat
     1981 ggggaattac agctattcct cagaagaaaa aaggagaatc ggtcacgacg tttggctcac
     2041 caacagcatt tgctgtcaat aaaaactcaa agaaacaaaa agcggcgcaa gaatttattg
     2101 aatttgcagc cagtgaagaa ggagcaaaag tattagcagg agtaggagta gttccttcat
     2161 atcgtacgga tgagattgat cagctttatt ttaatctcgc tggaatgcca acggatgaaa
     2221 tttctaaaaa agctttttct cctgatgaaa tcaaacttga atttccgatt gatacgtatg
     2281 ggcctgcaat cgataagatt ttacaagaag aatatgactt agttttggtt ggagatgaaa
     2341 cgccggaaaa aggaacggta aatatggaga aacgtgtagc tgcggaaaaa gaataatcat
     2401 gaaaggagag aagccaagag ataaaacact cttggtttcg tcatcgaaat ggagaatagt
     2461 ataaataaga aagctacaaa tcatttgcgt agaaaacgaa cgtggatcgc ttattcgttt
     2521 atcgccccga atttcattgg ttttttcgtt tttacattaa taccaatcct gttttcgctt
     2581 gtactagcat ttatgaaatg ggattctttt tcaacgccag aatttgctgg actagataac
     2641 tttcgtaaaa tggccaacga tgagacattt tggatttctt tgaaaaatac ttttttatat
     2701 accgctgctg tagtgcctgg cacacttgtt tgttcgttag ggctagcttt actactaaat
     2761 cagaaaatta gagggatgaa gctttttcgt acgatatttt tctttccgta tgttacttcc
     2821 ttagtagcaa ttgctgttgt ttggaatatg ttgtttcatc caacagtggg acctattaat
     2881 atctttttaa gacgatttat tgaacatcct ccaggttgga cttcaagttc aaattgggcg
     2941 ctttgggcaa ttgtaattgt cagtatttgg cgagggatgg gttattacat gattctatac
     3001 cttgcaggac tacaaagtat ccaaaaagaa ctatatgaag cgtcttcgct agatggagca
     3061 aaccgttgga aacaattttt gaatgtgaca ttaccttcgt tgagaccaac aaccttcttt
     3121 gtaacgatca tgcttgtcat caattgtttc aaggtgtttg accttgtgca agtgatgacg
     3181 gatggcggcc ctggtcgagc gacaaatgtg ctggtttacc aaatctacaa tgaagcattc
     3241 aaaaaatttg attttggtta tgcttcagct atttcacttg ttttgttcgt aattgttttg
     3301 ggcgttacgg ttgttcaatt ttcttggaat aagcgtcgta cttaggaggt gtgatatgga
     3361 agagagtgtt cgaaatgaaa gaaaaaaagc aaaaattcgt tcaaaaaaca tgccctttat
     3421 tcaatggttg ggtatgattc tgctgattgt attagcttta ttgacgatca ttcctttttt
     3481 atggatggtt tctgcttcat tcaaagcaaa taatgaagtg ttaacgattc cgattcaatg
     3541 gatccctaaa acttggcatt tagagaatta tctggttatt tggtctcgta ttcctttagt
     3601 gacatttttt aagaatacag cttttttaag cgttgtgatc acgttgattc agttgtttac
     3661 ttctagtttt gctgtttacg ggttttctga actaaatttt aaagggcgcg atattttatt
     3721 tttagcatat atcggcacga ttgctgtccc ttggcagtct tatatgatcc cgcagttcat
     3781 tatgatgaga aaagtgggtt taacagatac gttgtggtcg ttggtgctat tacaagcgtt
     3841 caatgctttt ggtgtgttct tgttgaagca atattacagt agtatcccag attctttatg
     3901 tgagagtgcg cggatcgatg gcttatcaga gtgggaaatc tatcgcaaga tcattttacc
     3961 tcttacaaaa ccggcgattg ccagtttgac gatcatcaca ttcgttaata catggaacga
     4021 ttatatgggg ccattcattt atttgtcttc tacggaaaat aaaacaatcc agttagggtt
     4081 gaaaatgttt attgggctat ttgatgcaga gtacgcatta atcatggctg cctcagttgt
     4141 ttctgttctt cctgttgctt ttatattttt agcgatgcaa aaatattttg tagaagggat
     4201 cgcttcatca ggaatgaagg aataggaggt gattatgaaa gagcagcgtt ttgacaaaaa
     4261 tgtttatatg gaattctttt attggttgta tcaatcattg gcaagtagcc tttgtttttg
     4321 gtgtgtcaat atcttgtata tagcagctgc gttccttttg tcgatagatg gaaggaatgt
     4381 cttttccttt attttttctt tactttttat tggtccaggt tgcatcgtga tgataggtat
     4441 gacagaagaa ttagcaaaag aaaaaagttt ttcaccagta cgtttgttca taaagacgtt
     4501 tcgccaattt tggctaaagg gattttttta ttggctattt gcttggatag ttagtgtgat
     4561 aatgattttt gattgtttct tttttatacg tttttcttat ggaaaatggt tgattccgtt
     4621 gtttgtttta cttgcttgtt ttacttgctt gtttatcagt ttcctttagc atcaactgct
     4681 ggtattttca ggtgagaaat ccagcgtcga aaccaaatca agttctacgg atagcgttct
     4741 actatacgtt gaaaaaatgg tatgtgagtt tactagattt tttactattg acaagtttgt
     4801 ttctcttctt tttcgtaaag ccccaatggt gtattctact aggtccttct atcgtatttg
     4861 gtttgattta cttcaacaat cgtaaattga tgagaactat ggatctgtag actttataaa
     4921 ttgaaacttt caattaagaa tgacagtttt ttatgtaaaa actgtcattc tttttcattt
     4981 tttgaaacat atggctaaac aaatgaaata aaacatgcta tacttttgaa tgaaacaggt
     5041 ttagaaactg tatcacttat ttgtgattat ttctaactaa taattaaaaa taaagcataa
     5101 aaaggacgat gttcaatggc tgaaaaaatg aaacaaggtt cgaaatctgt agtagaaagt
     5161 ttgattaatc atcatgttga ttatgtattc ggtataccag gtgcaaaaat cgatggtgta
     5221 tttaatgaat tagaggatca aggtcctgaa ttaatcgtga ctcgtcacga acaaaatgct
     5281 gcatttatgg cacaagcaat cggacgtatt acaggagagc caggagtagt tatcgcaaca
     5341 agtggtcctg gtgctagtaa cttagctaca ggtttggtaa cagcgacagc agaaggtgac
     5401 ccagttttag caattgccgg acaagtaaaa cgaagcgatc tattgaagtt gacccatcaa
     5461 agcatggata atgcagcact gttccagcca atcacaaaat acagtgcaga aatccaagat
     5521 ccagaaacaa tttcagaagt gattgccaat gcttatcgta tggctaagag ttcaaaaaaa
     5581 ggcgcgagct ttatcagtat cccgcaagat gtagtggatg cacctgtcca aggtaatgtc
     5641 atcaagccat tgagcgatcc taaattaggt tctgcttctg cagatgatat ccgttaccta
     5701 gctgaacgca ttagagaagc aaaactaccg gtactattag taggtatgcg aggatcaagt
     5761 gaaaaagaaa cgttagccat caggcaatta gttgaaaaga cagcattgcc tgttgtagag
     5821 acattccaag cagctggagt gatctcacgt gaattagaag cgcatttctt tggtcgtgtg
     5881 ggtttattta gaaaccaacc aggagatatg cttttgaaac gaagtgatct agttattgca
     5941 attggctatg atccaatcga atatgaagca agaaactgga atgcggaaaa agatgcgcgg
     6001 atcattgtga tcgatgaagc gccagctgaa atcgatcctt ttatgcagcc tgaaagagaa
     6061 ttgatcggtg atatctcagc cactcttgat ttattgacag gttcattaga gcctcaacaa
     6121 gtgtcagaag atgcaaaaga atatttagca tctcttcaag caaaattaac ggagcgggac
     6181 attgttcaat caaaaggaga agcaggtatc ttgcatcctt tagaagttat taacacgctt
     6241 cagtcaaaag taacagatga tatgactgtt accgtagatg taggtagtca ttatatttgg
     6301 atggcacgcc actttagaag ttatgaacct cgtcatttgt tattcagtaa tggtatgcaa
     6361 acgcttggtg ttgcattgcc atgggcgatt tctgctgcat tggtgcgtcc aaatacacag
     6421 atcgtatcag tttccggcga tgggggattt ttattctctg cccaggattt agaaacggcg
     6481 gtacgtaaaa aattgaatat cgttcatttg atttggaatg atggacacta caatatggta
     6541 gagttccaag aaaaaatgaa atatcagcgg gcgtcaggtg tagactttgg tccagttgat
     6601 tttgtgaaat atgcagaagc ttttggcgct aaaggaatcc gagctacaag tgtagaggaa
     6661 ttagaaaaag ctttagaaga aggatttgcg acagaaggac ccgtaattat tgatattccg
     6721 attgattacc gtgataatga gaaattggga gaaacaatct taccagatca attctattaa
     6781 ggaagtgtcg acatgactga aaaaatctta taccagcacg ggacattagg agctttgatg
     6841 gccggcttga tggatggaac agaaacgatt gctcatatat tagaaaaagg aactctggga
     6901 ttgggaacat tgcatgggct tgatggtgaa gtcatctttt tagatggcgt agcttatcaa
     6961 ggaagatcag atggctcagt tgcccaatta gatggaagtg aacttacccc ctatgcagca
     7021 attacagatt ttacgccaga tactagtttt tctgtctcaa aaactgcaga tggagaacaa
     7081 ttgaaaaaag acatattagt aagagaagcc ggggaaaacc tatttttggc agtgaagata
     7141 actggattat tcaaaaatat gcacatccgt atcatgccga agcaagaaaa accttacaga
     7201 agactagcaa aaatttcaga gtctcaacca gaattccaac aaagcaatgt ccaaggaaca
     7261 ttagtcgggt tctttacgcc tgaattattc caaggagttg ctgcagcggg atttcacctg
     7321 cattttatcg atgatacaca tacatttggc ggacatgtaa tggattttga agtggctgaa
     7381 ggaaaagttg agattagccg catctcgtcc cttgtacagc attttccagt tgatgatccg
     7441 acttttgttc acgaaacgat tgattatgct gatttagcag cagaaatcca acaagcagaa
     7501 tagaaaaaga cagcgagatg cgttcaaggt gattaacctg acgtatctcg tttttttgag
     7561 gagaaaacct agcgtttaca aaaaaactga gctataatct tctccataga tcaaaaagga
     7621 gcggttttta tcatgtggac agaaaaacag aaaaaagatg catacgaaat tttattatta
     7681 cagcaacaag gattattaga agcagaagat aactggttag caaatttagc aaattcatct
     7741 gcattgttga atgagacttt gcctgagact gtctttgcag gatattattt attcgatggt
     7801 aatgaattga ttttaggacc gttccaaggg cgagtttctt gcacacgtat caagatggga
     7861 aaaggagttt gtggagaatc agctgaaaaa caagaaacat tgatcgttga tgatgtcaaa
     7921 acccatgcaa attacatttc ctgcgattca gccgcacaat cagaaatcgt agtgccaatg
     7981 gtaaaagaag gtaatttaat cggtgtttta gatatcgatt gcggagtaac gaaagggtat
     8041 gatgaaatcg atcaagcatt tctagaaaaa t
//
LOCUS       DAFKHN010000105         7874 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFKHN010000105 DAFKHN010000000
VERSION     DAFKHN010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.105"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            45..242
                     /locus_tag="LY912_002543"
     CDS             45..242
                     /locus_tag="LY912_002543"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956184.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(285..860)
                     /locus_tag="LY912_002544"
     CDS             complement(285..860)
                     /locus_tag="LY912_002544"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBM6956185.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1015..1541)
                     /locus_tag="LY912_002545"
                     /pseudo
     CDS             complement(1015..1541)
                     /locus_tag="LY912_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1998..3509
                     /gene="gadC"
                     /locus_tag="LY912_002546"
     CDS             1998..3509
                     /gene="gadC"
                     /locus_tag="LY912_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBM6956186.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            3522..4922
                     /locus_tag="LY912_002547"
     CDS             3522..4922
                     /locus_tag="LY912_002547"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBM6956187.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(5087..6522)
                     /locus_tag="LY912_002548"
                     /pseudo
     CDS             complement(5087..6522)
                     /locus_tag="LY912_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            6915..7508
                     /locus_tag="LY912_002549"
     CDS             6915..7508
                     /locus_tag="LY912_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBM6956188.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
     gene            complement(7492..>7874)
                     /locus_tag="LY912_002550"
     CDS             complement(7492..>7874)
                     /locus_tag="LY912_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBM6956189.1"
                     /translation="FSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKG
                     CPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVG
                     YRNQRLAQRILDNELGCANASEAV"
BASE COUNT         2455 a         1353 c         1442 g         2624 t
ORIGIN      
        1 tttgaaactg ctcttttctg cggctgtatt tcttgatttg tttattgaaa gattcgattg
       61 tagaaccaga aggaatggag aacacttttg aactttacaa caaaactact gttgataaat
      121 taattccaat tttagttcca actgatttaa atggtcatga tgttttactt cgttttaacg
      181 gatttttagg tgaggattat agatacctaa aaatttctga tcctcaacct ttaacagaat
      241 aataaaaaac gtgtaatcaa ttatttgatt acacgttttt tatttcaatc ttcgttgtag
      301 tagtggttgc gacataccga aaggtaatct tcattacctc ctactacaat ctgttcacct
      361 gaataaactg gaataccatc aacaatacga gcattcatta cagccttttt attgcaaaaa
      421 tggcaaatag ttttaatttc ctcaatttta tcagcaaatg tcaataatgc ttcggatccc
      481 ttgaagagat tattttgaaa atcattcttc aatccatagc aaattactgg tacttcctca
      541 ttcattacga taagtgatag atcaataata ttctctctac ttaaaaattg agactcatcg
      601 accaaaatac aatcaacttt tccgtactga tcaataatct ccactaattc tccgtacaca
      661 tccatttcag aagtaattgc aatagctggt ttcgaaacac ctatacgact ctcaactttt
      721 ccaaatcctg atcgagtatc tattgcgctt gtcattatga taactctctt cccttgttct
      781 tcataattat gagccacttt cagtagctca atactctttc cactattcat tgttccatat
      841 ctgtaaaata attgtgccat taaatttatt cccttctttt acaattcaat tattccttaa
      901 ttccatctgc ttttatgcag ctgctcgttt attccttgat atgtctataa catctactat
      961 ccctaaaacc aatttataag ccattagaga tggtattcct gaacatctct catattgttt
     1021 tttgagtggt atatcatctg aaaaactgaa ggaatcatga aaatagcgac atacttatca
     1081 tttagagttc taactttaaa tgcatttact tcttcagtca gcactttagt catgttggac
     1141 atggtttggg gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac
     1201 atggtaatac cttttcggaa gaggtgaatg acggtctcct ctaatgtgtc attcgtccgt
     1261 ctataagcag gaacagtctg ttgcttgaac tcgccattgc ggtcgcgcgg aatctggaga
     1321 tgaagttccc catactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc
     1381 gtgttaaaac caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg
     1441 agaagcgtat tgacagcttt ttccaaatgg acacggaata atccattcaa atcgcctttg
     1501 ttcgctagag tctttaggat ttctgtagta aaatcgttca tatggaagtc ctcttttctg
     1561 tgaatgtgtt gtggtaactc tattctacag aagggacttc cttttttcta tttacacaaa
     1621 atattttaca ctctcaacaa aagtatcttc gattaatact tgctcaagtt atgtgcagct
     1681 acgaaaaagt aggtaccgag gtactttctt tttcgcagct ttttttggac ttatgagaag
     1741 tacattcgct ggaagaatac gatataaaac gagctttttc actaaagata ttaatagagt
     1801 gaaagaaaca agcttttgtt gtcagttttt tcacttttct aaaaatgaaa ataaaaaatt
     1861 ctggaagtgg agaagaattt tgcttgctat actttgtctt gtagaaaaga ggtagacaaa
     1921 ataatgcaag ctcaaataag cgattttcca taaccttggt aggaatgaca aattaaatag
     1981 gaaagggaag taataatatg aataaaaaaa agttatctct attcggtttt tttgccctga
     2041 cagcttccat ggttttgact gtttatgagt atccgacctt tgcaacatca caattacatt
     2101 tggttttctt tcttcttttg ggaggtattt tatggtttct accagttgct ttatgtgctg
     2161 cagaaatggc aacagttgaa ggatggaaag atggtgggat tttcagttgg gttagtcaaa
     2221 ctttaggaga acgttttggt tttgcagcta tttttttcca atggtttcaa attacagtag
     2281 gttttattac aatgatctac ttcatactag gagcgctgtc gtatgtaatt aattttccag
     2341 agcttaatac agatccattt atcaagttta ttggtgtatt agtcattttc tgggtactga
     2401 ctttttcaca gttgggcggg accaatcgta ccgctaaaat tgctaaagca ggatttgtca
     2461 ttggaattgt tattccttcg atcattctct ttggtttagc agcagcctac tttatcggcg
     2521 gtaatccgat tcaaatggct attaatgcga aagcttttat tcctgacttt tctcagcttt
     2581 caactttagt agtatttgta tcttttatat tggcttatat gggcgtagaa gcttcagcat
     2641 cacatattaa tgagctggaa aatccccaaa gaaactaccc attggcaatg tttttactag
     2701 tgattttggc catcgcctta gatgcaatcg gcggtttctc agtagcagcg gttattccac
     2761 aacatgactt gtctctcagt gctggtgtaa tccaaacatt tgaaacgctt attttacatt
     2821 ttaacagtca tttacattgg ttggtaaaag tgattgctct catgattgcc tgtggcgtta
     2881 tgggtgaagt tagttcttgg gtagttggtc catcacgagg gatgtttgca gctgctcagc
     2941 gaggtctgtt accagttttc ttccggaaaa ctaataaaca agacgttcca gttccgttga
     3001 ttatgataca aggaattatc gttactattt gggcagcagt cttaactttt ggtggaggag
     3061 gcaacaattt atcattctta gtagcaatct ccttaactgt tgtcatttat ctcgtaggat
     3121 atttactatt tttcctaggt tactttgtat tagtttttaa gaaaaaagac ttaaaacgaa
     3181 cttacaatgt accaggaaaa actgttggca aaacgattat cggtggaatt ggttttattt
     3241 tatcagtgtt cgcattgctt atctcttttg taccaccagc ttcaattgca gctagtgagc
     3301 accgaacata ccaaatcata ctacttatta gctttgtagt gactgttctt ttacctttta
     3361 tcatttatga agtacatgat aaaagtgctc acacaactat tgaggaacct actcacgtga
     3421 aagctgaaga cgttaatccc gctgtttatc cagctgctag aggagagcac cacgttacaa
     3481 aaaatgatga acatatttta aaacattagg aggaattcat tatgttatac ggaaaagata
     3541 atcaagaaga aaaaaactat ttggaaccaa tttttggctc tgcaagtgag gatgttgact
     3601 tgcctaaata taagttaaac aaagaatcca ttgaaccacg aattgcttat caattagtac
     3661 aagacgagat gttggatgaa ggaaatgcgc gattaaactt agctactttt tgtcaaacgt
     3721 atatggaacc tgaagcagtg aaattgatga cccaaacgtt agaaaaaaat gcaattgata
     3781 aatcagaata cccacgaaca acggaaattg aaaaccgctg tgtaaatatg attgctgatt
     3841 tatggcatgc tccaaataat gaaaaattca tgggaacttc aacgatcggc tcttcagaag
     3901 cctgcatgct gggtggtatg gccatgaaat ttgcttggcg taaacgtgct gaaaaattag
     3961 gtcttgatat tcaagcaaaa aaacctaacc tggtgatctc ttctggttac caagtttgtt
     4021 gggaaaaatt ctgtgtatat tgggatgtgg aactgagaga agtcccaatg gatgaaaaac
     4081 atatgtcaat taatctagat actgtcatgg attatgtgga tgagtacaca attggtattg
     4141 taggtattat gggtattact tacactggtc gttatgatga tatcaagggt ctgaatgatt
     4201 tagttgaagc tcacaataaa caaactgact ataaagtata cattcatgtt gacgctgcat
     4261 cgggtggctt ttatgcacca tttactgaac ctgatctagt ttgggatttt caattgaaaa
     4321 atgttatctc aattaattct tcaggtcaca aatatggttt ggtatatcca ggtgtgggtt
     4381 gggtcttatg gcgtgaccaa caatacttac cagaagaatt agtatttaaa gttagttact
     4441 taggtggaga aatgccaact atggctatca acttctctca tagtgcagca caactaattg
     4501 ggcaatacta caactttgta cgctatggct ttgatggtta tcgtgatatt caccaaagaa
     4561 ctcatgatgt tgctgtttat ttagccaaag agatcgaaaa aactggtatt tttgaaatca
     4621 ttaatgatgg atcagaattg ccagttgtgt gctataagct gaaagaagat cccaatcgcg
     4681 aatggacact atatgattta tctgatcgtc tgttaatgaa gggatggcaa gtcccagcct
     4741 acccattacc taaagacttg gatcaattaa ttattcaacg cttagttgtt cgagcagact
     4801 ttggaatgaa catggctggt gattatgtac aagatatgaa ccaagcaatt gaagagttga
     4861 ataaagctca tattgtttat cataaaaaac aggatgtgaa aacgtacggc tttactcact
     4921 aaaattcttc agagaaatat aaaagaagtt aattaactaa taaaaggagt tgtgattacc
     4981 acacagctcc ttaaatctat ttgaataaat atatgatatt catttgttac actctcaatc
     5041 ttagctgttg ttctattcat cattactctt attgtaagta gttcagtcaa atttgcttgt
     5101 tcaattgatc gataacagta tgaattgttt gaaaagtaat cggatatata attgttttct
     5161 cactacctaa gccttcttgg tataaagaac tatcgcaaag tataatccgc tgagtacaaa
     5221 agaaagtgtc gtctactatt tctctaagtt gtttacaaat gatattacta atagaaaagt
     5281 gttctcccaa aatgtcttct aactgttgtc gatagtataa atacctaaag tctgacggag
     5341 ctactatgaa cacttcaatt ggagatttcc gtttatgctc atttaaaaga cttaaactaa
     5401 tggttagttt acgaatagaa ttctcattcc aacgcagaaa taaattgttt tgttttcgcc
     5461 attgttcaag aatttcatga acttctaagt acaaagcgcg ttgctcttca tttaacaagt
     5521 aagtcttatc aggttgaaat atctgaatat cagcccaaag tgagcggata aacgggagaa
     5581 gtgctttatc aaaaagtatc tgattttctt cagatatatt cagagataag ataagttttt
     5641 gactgagctc aatcaccaaa gggttatctg ctacatggtt ttgataaaca acgttcaagt
     5701 ctttttgtaa caattcaaag ttatcgcata gataatttct agagttgaat agaaagtaga
     5761 tataaaggca ttcatcttcg tcatgacata aagagaaaga aagttgctct aatcctttct
     5821 gtattagctg aaacaaggga gtatgtcggg caactctttt ttcttcctga ctaaaatata
     5881 ttgggttagt cttagatctc tgcaaaccga tagcgatacc taataaaata aattgttttt
     5941 caactgtagg gtaacttctt gaaaaaaatg tttttctaca taatcaatca attgttgacc
     6001 gctttgaata attgatttat ttagctggat caactctgtc cgatttgtct catagattat
     6061 cgttagtaac aaacttcgat aatccttttc aggaatttca aaatggccat cagcatttaa
     6121 gtactgcatt tgtttaaaaa aattaatcaa ctcatttcgt aagttgtaaa ctttgcttaa
     6181 cgaaatgaag gtagtatcag ctatattact ccaattgtgt tcccctgata aataatgtcc
     6241 tagtacattg aaaaagtcag agcgctgata gatgagttga gtgagtgcca acctcgaaaa
     6301 cgaagagtcg aatgcgactg taaagctact tctagatttc tccactgaaa taatttgctg
     6361 atggagtatg tcggtaatgc attccaagtc gttagtgaca gtgagtgggc aaacgttcaa
     6421 ttgatctgct atttcgcgaa tctgaatggt ccctttttcg tgtaattgct cacaaatgta
     6481 aacttgacga aaaatacttt tctccagata ggtttccaac atagtactcc tcctagtcat
     6541 tttatacata actattataa ctctaccaat cggaatagtc ctgtaatata ttgaatcaaa
     6601 aatataaatt ataaaataat tagatggggt atttggttta agtatccctt atatagtaat
     6661 aaatttatag gtgtgattct cgaattaata cccgaaaatg tgagagaatt tttatggatt
     6721 ttttaggata caaattaatt atttttgctt ttatcctgat taccagtcca gtactgtcgg
     6781 tatcccattt tgcagcaaaa tcatgttgat aaagtgacaa gaagactgat gagatatatt
     6841 atccaaattg agaagataat taatcggatt cttgagtata ccctactttt taagaaagta
     6901 gggtatacaa gcgtatgaat aaagacataa ctttccctgt gatggacgtt cggcttgttc
     6961 caattaccaa aatacaggcg aacgattata atcccaatcg agtagcgtct ccggaaatga
     7021 acttattgga gctttctatc attgaagatg gctttactca accattagtt tgttattaca
     7081 aggaaaaaga agagaagtat atcttggttg atgtgcttca taggtatcgt gttgctaagg
     7141 aaagactcaa cttaaaagtt gtaccggtaa cagttattga taaacccata gaagaacgta
     7201 tggcttcaac aattcgacac aatcgtgcaa gagggaccca tgaaataaga ggaatggaaa
     7261 ttgtcatcca aagattagta aaaaatggat ggtcagacaa gagaatatcc aaagaattag
     7321 gcatggacat tgaagaaatt tttcgcttta agcaagtgtc tggtggaatg gcaacagttt
     7381 ttttgacaaa ttttataagg tgcagaactt ctttccgtat gctattccga ttgtccttga
     7441 caatgagcct cctcggatgt gacgatcttc ggcaggagct aacagttaaa gttagactgc
     7501 ctcgctagcg ttagcacatc cgagctcatt atcaaggatt cgctgcgcca atctctggtt
     7561 acggtaacca accggtgtct cgtagccaag tgtaccgtgc aaccgaaggt ggttccacca
     7621 atttacatag tcaaataact ccaaatccaa ttgttgtaag gtttcaaatg tgtattgata
     7681 gacaaattct actttcaacg acttataagt tgattcagct acggcattat caaaaggaca
     7741 gcctttatga ctcaatgatc gattgatgtc aaaagttgtt aataattcat caatagcttg
     7801 gttatcaaac tcttttccac gatcagtatg aaaaatctca acctctgtca gaggttgttt
     7861 gatacggcta aatg
//
LOCUS       DAFKHN010000106         7839 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFKHN010000106 DAFKHN010000000
VERSION     DAFKHN010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.106"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..176)
                     /locus_tag="LY912_002551"
     CDS             complement(<1..176)
                     /locus_tag="LY912_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HBM6956190.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMIT"
     gene            complement(166..519)
                     /locus_tag="LY912_002552"
     CDS             complement(166..519)
                     /locus_tag="LY912_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBM6956191.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            complement(509..820)
                     /locus_tag="LY912_002553"
     CDS             complement(509..820)
                     /locus_tag="LY912_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956192.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            complement(817..1692)
                     /locus_tag="LY912_002554"
     CDS             complement(817..1692)
                     /locus_tag="LY912_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956193.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            complement(1702..2862)
                     /locus_tag="LY912_002555"
     CDS             complement(1702..2862)
                     /locus_tag="LY912_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBM6956194.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            complement(2862..3548)
                     /locus_tag="LY912_002556"
     CDS             complement(2862..3548)
                     /locus_tag="LY912_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBM6956195.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            complement(3511..4689)
                     /locus_tag="LY912_002557"
     CDS             complement(3511..4689)
                     /locus_tag="LY912_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBM6956196.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            complement(4709..6403)
                     /locus_tag="LY912_002558"
     CDS             complement(4709..6403)
                     /locus_tag="LY912_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBM6956197.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            complement(6381..6695)
                     /locus_tag="LY912_002559"
     CDS             complement(6381..6695)
                     /locus_tag="LY912_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBM6956198.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            complement(6798..7079)
                     /locus_tag="LY912_002560"
     CDS             complement(6798..7079)
                     /locus_tag="LY912_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956199.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            complement(7084..7428)
                     /locus_tag="LY912_002561"
     CDS             complement(7084..7428)
                     /locus_tag="LY912_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBM6956200.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            complement(7454..7621)
                     /locus_tag="LY912_002562"
     CDS             complement(7454..7621)
                     /locus_tag="LY912_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBM6956201.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
BASE COUNT         2266 a         1640 c         1126 g         2807 t
ORIGIN      
        1 gtgatcattt ctatttctcc tgtttcgaga atgaagtaat taaaatcatc aggtagctca
       61 tcctcgccta cggagtcttg aaagagtttg aggccaaaat gctcttctaa ggaagttttg
      121 atagcagaaa tttgcttatt taaacgttct ttttctttag aattatcaat caccatattc
      181 acccacactt tcaagataaa aatagatata aaaattatcg taatcggcat agataacgtt
      241 gtaacgcata ctatcgatta cgataaaata ttgatcttta ttaaatttct tggcgattgg
      301 atgaaatgga gtctttactt tcttagttaa tttcgatccc atcgcatcca tagctgttat
      361 atcactatct ctcatggaaa gatttctaaa ttttaaagaa gtgatttctg tatcttctac
      421 accaatcttt tttcctagtt catttctttt ggtagtttgc gtcaaaatct ttaaccaacc
      481 atcgttgaat gtttcttcga gtctacgatt attcgccatt cacatcacct gcaatatatt
      541 cttgtagcgc ataatgttga atgaaaccta ataactcact agcgaaattt tgttcaaact
      601 catctaaagc acgattccag tcgtatctac atctttcgat tagcaatccg tattctaagc
      661 tttcaggaga aaaagaaagt gttgtactca ctttactttg aagataaaca gcatttttag
      721 ctatcatctt tttaattgac tcatcttctt cgttccaggt aacgtaaata ttatccttca
      781 cagctattag caattcttca gtcacttgtt caggcgtcat ctaaccaccg ccttaattgc
      841 tttaacatat gcgtaagagc attttttctt gtttacaaat gataaatctt catcaaaagg
      901 cgtagaagtc acgtatctcc ctttgaaaaa taaatcttca tcgtttgttg ttactccagc
      961 attgtgtaag atttttactt ctttaacttt ttctattgga tcagtagcaa aacaaaagtc
     1021 taattcctcg tgaactttag gaccaatatt gaaatacatc atgttccaaa gctgtgccca
     1081 catctcggct gtccagattt gtatatttgt tttttgccct ctaaggtagc gatatagccg
     1141 attagaatcc agataaacct ttttccaata attcgcttta ggacggttaa taacccactg
     1201 tgcgcctcct gaattagtgt ttatagtttc caaagattct actgtaacat ttacaatgtt
     1261 tgccatatct tttagaatat tttctccgtt ttcacagctt ctaatataat caagacttag
     1321 ataactacag cagtcgctac aataccaaac atcatcttta gaaggcaatt tgcgcaaatt
     1381 aattctttta ttgaaaatga catccgaatc gatatagaaa tatcggtcgt cctcacgcga
     1441 atgatcttct tctaaatatt tccaccataa atatggttta atcgaaggaa tatactcttt
     1501 gtcgtcccgc agatcatcgt acacatgaac ttcaacacca tattccttct caaaaaaaat
     1561 aggaatctga tcatcgtgtc tgctgaaaag caatacgata tctttgattc ctagtttctt
     1621 cagattagtt aaacaaactt caagctccca tttaaaccga ttgattgccg gctgacaaag
     1681 aatatacttc attctgatca cctacgcttg tgttgtagtt gttgtggttg ttggttttgt
     1741 agttgtagta gtagttccca aagcgctaat atctaataca atgaaactat cgttacgttt
     1801 aggttgaccg tttgcatatt gtttagctag ataaatgcgt tcgtcttcaa caaaatggta
     1861 ttcatctgaa gcttcaattt ttagtgtaga tcctacaccc atgaagtaat ctgaggctac
     1921 cccaataact gcttttcctt ctggcacagc cgttgactgc aaatctgaaa ctggtactgg
     1981 caatacttgt acgtattctc cattagcagt tagtacagtc ttagctggga atactttaga
     2041 ccagtaatca gttggattca caattaggac cacatcagaa ggattcacat tacgataaat
     2101 cggatcattc acaccttcga tattgaattt tgatagtcgc gccatcaaac cgcccatagt
     2161 tacagcatct aaagctgtaa taggttctgc ttttttttca gcatattctc cgctagtttg
     2221 tttgctcatg tcacgcatca ttccgactgg catatcttta ccagtaccat caacaattgc
     2281 ttgttctaat gcaattctca atgattctac taaaacagta cggacataac gatctaacca
     2341 tactggacct aaatcaagca ttgccttaca tacaggaata taacctgata gcttgaactg
     2401 cttcatgtta attacatcaa agccattatc taaaactttt ttaacagctt cgcaaagttt
     2461 accccaccat gctggattga ctccacgtga cacaatccat tctgttacac cagttgtgtt
     2521 aacaaaagta attttttgca atagtggatg agattgttct aaatcttcaa atacacgttc
     2581 aaatacagta gctggcacta attcttcgac ccctgcaaaa ccttcgtttt tcactacttc
     2641 gttatagaat tttgtttctt gtgtagttaa tacacgctga ccacggttca ttaatactaa
     2701 ttgatcttga ttttttgctg ttgcttcttc taaaatttta tcctgaattt ccttagataa
     2761 gcttaccata gctgcgctaa aagattcttc gttaccatct ttaaaagctt tcatcaattg
     2821 gtcgcttgca gctgttacac cttttaaatt tttaactgtc attattttac atctccttgt
     2881 ccaaatgttt tatttaatgc tgctgtaaat gcagcaattt tttctgctct tttttcttta
     2941 acgtcattca aaatttcttc aacgctttgt tcttttttag cttcagtacc tgagctattt
     3001 tctgcatcga taatttcatc gaccaatcca taactcaaag ctgtttctgc atccataaac
     3061 gattcttttt caagaagttc ttgcaatgct tcatctgtgc cattgaatcg tgttttatat
     3121 gaagccttta ccgatttatc aattgattcc agttggtcag caatcgtacg gaagtcatcg
     3181 acatttcctt ctccgtatgt ggaagcgcgg tgaatcatca attgtgcatt gttgtagatt
     3241 tttatagtat cgccagccat tgcgataatt gaagcagcac tagcggctaa gccgttaatc
     3301 acaacgttaa cttttgcttt atttgactta agtaagttcc caatagcaat cccttgaaat
     3361 acgtctccac cgtttgaatt aattactact tcaatttctt cttgatcacc tagactatcc
     3421 aaaatatttt tgattccctt gtcagtattc ccttcaaaga accaactaga accaataaat
     3481 ccctgaataa aaatttgcgg tactgcgcct tcattcttta ctgctagaaa tgttttcatt
     3541 gtcgtcattc gcctcacctc ctttcgatac ttgttgattg tttttagtta taaatatttc
     3601 atctgccatc gccttatcag agcgatcatt tccaacgcgt tctcttcctt cgttgattgt
     3661 aaatactcca tttctaatgc ctacatcaat agcgtcaacc aaatctttga agctagtaat
     3721 cttgatcata gttgtatcca cacgtacaaa attccctgac aagtattctt ctacttcata
     3781 gagactagcg ttaaacgcat cctgaataag ttcagcaatc ggtatgattt cgaacattaa
     3841 aaaagcgtcc acttgatccg ataacccact catgtctccc tttagtaggt ttttcggaac
     3901 gtgaaacgct gctgctgtca tctcaaagat gtcgtctatt aagtttttta tatctcttga
     3961 attgctttgg aagtttccgc tgaaatcttc taatgtgtac tcattttgta attgaaatac
     4021 cgcacctgca ttatcagctt ccataaaagc cttaaattgt gatgtcatca ttttattgat
     4081 ttgatcttgt gttgtattgt cttgcggtcg gaataaattc cctttcagta cgtatctacg
     4141 agcgttagag cgcttgtaaa cattcatggc actagaaatg agtttcccat acgcttgata
     4201 atacgcatcg actagttgcc taatttgttg atctgcgtat tttatataga taacatcact
     4261 ttctagaaat tctctatcaa ggactatgtt gttaatttgc acttgagaaa acacatcatc
     4321 tttcaatgca tattctgtga catcccaact atccgcaata aatatttcgc tagaattatt
     4381 agacggagaa acgatcaata cttcattgta gaatattaat ctcctgatca gtttttttct
     4441 aaattctgtt gcattatttt tcttattagg agctacattc agcctatagt aaagatcatt
     4501 ctttttattt tttccatctt catatgactt gaattccgct ttactcatcg catttgcaat
     4561 caaatcaata caagtttcaa tcgcaaattt tcgatacaca aaatcaactt gcaatttaca
     4621 aaagtattct tctaaaggaa ccgttgcttt ttttgtgaag tatcctaccg ccttttgaaa
     4681 aatccccact ttctcacctc ctttcaagtt agaatactag aggagtaaat ccagttcctg
     4741 tattttctac tgagctattt gtgactgtta caggagcaga atcataaata tcatctaaaa
     4801 aattcaaacc atgaaggaat gaaaaaaagc catccgtttt tctagtttca ggttctattt
     4861 tttcatagcg tatatttcca ttagaaatat gctcttcata tacattcatg caataccaac
     4921 gcataatcgc atcgtcacca aaaaataaac gttgattaat aaaaaggtca tcaaccagat
     4981 cttttaacat accatgtgta acagatccgc ttcgaacaat ttccacagta aaacctgctt
     5041 cttctaaagc gggcttcaat atttttgcac ggtacatatc catagcgatt tttttaatat
     5101 aatatttatt actcatttca agaaaccaac ctacaatata atcagcttct atattttttc
     5161 catgaacgat ctgtgatttt ccttgatcta tagaaatatc tataacctct cgtttgatgt
     5221 tttgtaatcg aagggctgat tcgtggataa aagtatgttg tgtaaaataa acatctttat
     5281 cgtattttcc tagcaaccca acgctggcaa aatctcgtct atcagcaaaa tcgactgttc
     5341 ctatcacttc atccattttt tcaggaaatt ctttttcttt cgtatgcaga acatcatcat
     5401 atgaagcaac agcaaatcgt gtatcttcca taggtctgtt cattcgtttg gtcatgaacg
     5461 taagtcttaa accagcatta cgttgcattt gagagtattc ttgaaacatt ttccgtttta
     5521 aatctgcatt gtaattaata gttggacaag ctttttccca catgtcggga tcatcaactt
     5581 cattatcgtt atccaagcga caaataaatg gaaacaaact agaaaattct gctccatcct
     5641 tgtcaattcc aagttctcca gaaagaatca tttttgattc ttctataatg tcatcaagcg
     5701 gaccaccacg aacatgacca ttagttgtat cataaaattc tctataatct cgaattttac
     5761 caccaccaga agtagccaca tttatcattg aataatcttc attttcgtga atttcatcaa
     5821 agcggtttgc acctggtcgc ttcccatctt ttgttctagc atttgccgtg ttataacgaa
     5881 gtttgctgtt tgtagcgata ttttgaataa cttccttcgt agctttaaat acttttttat
     5941 ctaaatcagg atgatcttta attactttaa atacatcatc aaaactagtc tttgcttggc
     6001 tttcattatt ggcatagata tcaatatcat aatttttaat accgtgttta gcggttagta
     6061 gaaagaagtt gttccaagaa gcaaaaccag ttttaccatt accacgtccc attaatgaaa
     6121 gatatctatt gaacactagt gttttatctt ttttccatcg aacaccataa ataaaacatt
     6181 gtagaaattt ttcccacgga attaattcga atggaaagta ttgtgctggt atattgattg
     6241 aatcctctac catctgctta tcgaagtaaa tatcttctct agtaaagact ctttcttcta
     6301 gataattttt tagcaataat tgctctttgc ataccttgat agtgccttct tctatagctt
     6361 tgaaccaatt ttcaatatgc ttataactca ggaattgatt catttgcttc acctaccaat
     6421 tcaggagtaa tggcaagttt atccaacatc aatcccattt gtttgttgac agaaacaagc
     6481 aacgctactg attcattctt tttaccattc tccagtctaa tgccgttctc ggatatatct
     6541 tcttccagtg atatcgccgt ttcccataaa ctgatataac gatcaacatt atctaagaat
     6601 ggctcaatat ttgttttctg actttccaat tggcttatta aagagcggcg taatttttct
     6661 ctgtagcgat tttgagacaa ttcgttttta aacattttag ccctcctttc atgataaagt
     6721 tcgaaaaaat ctcttttcct gacagccccc tccgtttcat cacccccaaa aaatttgcga
     6781 tttattttaa gggggggtta tctcaccatc ggaatgaaag cttcagcgaa gtcaatgtaa
     6841 taattaatct cttcaatact atatccaaaa acatttttta ttctttcgac gttattatct
     6901 ttattcaacg cttctcttac ttgattcact ttgtatttac tacaacagtt atctgataac
     6961 agatccctaa tacctacata gcgaacgtat atcaaacgtt taattaatcc ctgagtataa
     7021 gatgaatact cttcaatctt ttctgtatca tactctctgc cattatcatt gatgatcatg
     7081 cacttaccac ctttcacttg catcgaagtt agcaaagctt tctatcttct tctcttgttt
     7141 atctaatgct gtaagatatc tgccatgaac ttcattatga tgttcaacac ataaacaaat
     7201 aagattatct aaatctaaag ctaagtcagg tctatccttg acttccttta tatgatgaac
     7261 gttctctact ctatgatact tacctagtct tctacactct tggcattcat agtgatctcg
     7321 tttcatcgct ttctctctaa gcctgcgcca tttaggagac tgatagaact taaccaaacg
     7381 atcttctctt gtcaactgta atagccatct atagaattcc tcggtcatgt tccgtctcct
     7441 ttcgcaatct tatttaatgc ttagctattc ttttgccata caatggaata acttcattgt
     7501 tttcctttcg tttatatgta tcgctcttta ttggtcttct atactcatat actttttcgc
     7561 cattaccttt atgaacagtg attacttcat acttctgttc taagtattgt ggtctataca
     7621 ttgttgtttc ctcctttgtg caaaaataaa aagaccactc aaagagtgat ctaatatgta
     7681 atagtaactt gcacgatgca caaaacgcgt acgaaattgc gcacccctat atttttaaac
     7741 cgccgatgcc tcggttgctt aaagtcgctg gagtgggatt gcaccactca cgagaactta
     7801 ccaggctctc acgaggctac tcgccattta ccgctgcgt
//
LOCUS       DAFKHN010000107         7803 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFKHN010000107 DAFKHN010000000
VERSION     DAFKHN010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.107"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            405..707
                     /locus_tag="LY912_002563"
                     /pseudo
     CDS             405..707
                     /locus_tag="LY912_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2481..3248
                     /locus_tag="LY912_002564"
     CDS             2481..3248
                     /locus_tag="LY912_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HBM6956202.1"
                     /translation="MVEEEQGRLIKSKKRVQKHGEVFTPQRTVKDMLDLPGIKEACEE
                     LQTTFLEPSAGEGAFLVEVLTRKMAMVAREYNESLEQYENYSLLALSTLYGVELLEDN
                     AQTCVMNMFQVFNDLYREQSKKHGTAMKRKVQDSAKTLISRNIKQGDFLTKRTPDDNP
                     IIFSEWTPKTLRKGQKKITVNRTEYSLEDIYSGVTREFGEAYSALPVFEQLDLFSFDD
                     EVDEEVSNDPILRYVAMPITEVYKEEMEEIDDDSVEI"
     gene            3226..7623
                     /locus_tag="LY912_002565"
     CDS             3226..7623
                     /locus_tag="LY912_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HBM6956203.1"
                     /translation="MTTALKSKAKYFDYLPKYGSKLEHFLGIPNLVDAINTYRVTVNQ
                     IPNEVAIGTRRYSEVAARKIASNVGIDQQSMKYVDVLRELRVRNNITPTIADLFHKLR
                     KYGNVAAHENGIIPVSEAVESLVTLDTLLRVFARNLSGDKSLNPKEEITDEMFVITYN
                     TFDRKLIYIQSAKDADGTWKMYQGLEKIGDASVPENYEADFTPNSEYLREYASRRIKQ
                     YMTTAGVPFVLHWAQLAVNKKNQFFRDHDVHEVLKRSGYNPQTIGEDDTGKPNEWFSV
                     TVDVAKKAIQAVKDGKGSLDSEKDDFDEFKINFRPEQKDAIEQTKTVFKTKDEMLWNA
                     KMRFGKTLSSLQVIKESQYKKVLIMTHRPVVSDGWFTDFKKIFTDGSYIYGSKQDGEK
                     IQNLVDTEKPFIYFASIQDLRGSEWAGGKAGDKNYEFLAIDWDFIIIDEAHEGNETEL
                     ANNVKAKLRKEHTKVLELSGTPFNLFDKYDEDNIFTWDYTMEQEAKEKWSVEHPNEPN
                     PYEGLPKVSMFTFEIPNKFDYFDENKAFNFREFFRVKEDDETKLLHEGDVRKFLDYIT
                     TNDEKTNFPFSKPEFRENLRHTLWLMPGVKEANAFERVLETHPIFKDYNIANVVKTGD
                     SEHASDSDLELVRKAIGNPAKSKTITLTVRKLTTGVNVPEWTGVFFLSNTESPTSYLQ
                     AAFRAQTPFNHAELGIKKNCYIFDFAPDRALKIMSGSVGLTSKKGKVNSSEQKKKLER
                     MLNFLPILGKQGNVMKEFSVDRMLTALKKAYAEKAVRTGFEDSSLYNDNLLNLDQADL
                     TKFEDLKKIVGSSKPTKVKDFIVSDNGMSEEEYEKASRAEKKPKRQRTKEEQEAIDRA
                     KRLREQRNKMISILRGVSIRIPMMIYGMDIDIKDDVTIEMFLNLVDEASWNEFMPEGL
                     SKGRFREFIEYYDADVFVEAGRIIRRRAKSYDELDVIERTRKIGELFSTFKNPDKETV
                     LTPWRVVNMHLGNTIGGLSFFDEEYQNSTENGQPIVRWRKTDCTDDIFKENRKILEIN
                     SKTGLYPLYAATSMYYVQLLKQSDINAGRVDSEAIWEKVLSEQIFVISKTPMAKTITK
                     RTLIGYNAWKVNVEYSSELVTSMKRSINDGLTNLKGVYKNVKFDVIIGNPPYQEKDGG
                     SGASATPLYNLFVETSVKLSERYVSMITPSKWFAGGKGLDKYRDFMLNSSSLKVMVDI
                     VNGKEIFPNTSIGGGVSYFLWDKKYNGLTQYTNQHDGVSNTQERKMNEFPVFVRYNEA
                     ISAIHKIGEHASVGDFVISRNPFGLPTKIRGEEVQDSRNSIKVISSGGVGFVPLEDIT
                     KGQDMVGKYKVISSSLTSEHAGEPNKNGMFKVISTNRVIKPNEVVTDSYLVLFSADTE
                     TEAINYLKYLRTRFYRFLLLQAVTSIHLSKDKFMFIPVQDFTSGSDINWNVGIEEVDM
                     QLFKKYSFDASEILFIDQTIVPILHEEYY"
BASE COUNT         2697 a         1193 c         1691 g         2222 t
ORIGIN      
        1 caggttgtag aaataaagat aaagatttct atggatattg gtcaggaact gctgagaaaa
       61 ttcctgtaga ctataatttt aaaataacta aagacagagt aatagaacta caaaaaaatg
      121 gtgaaatggt ggattttaag tatactctaa gacataaaaa atttgattca actacatttc
      181 gttcaatcat gatatcaaaa gatgaattag ttaaagcgat tccagaatta aaggaaacca
      241 cgggaataag caatataacg ttcatgccta ttgacggtga aaaagataaa ttaactgtgt
      301 tggtaaattt ggatgaacac ttatcaacag ccactcttta taggactacg aaagatgaga
      361 gtccaattgg taaggtagaa aagaaaaacg atacaatatc aagacaaact gtagataaaa
      421 aaattgatac gttcataaaa acatacgcgg ctataccacc tacttggaaa cttgtaaatg
      481 aagataaggg aataacgata aatactgata cagagattcc gactgatgct caatctttat
      541 cagatttatt agctaatcta acaggagtca gtaatgcggt gtcagagcaa gtcggtaaag
      601 atattccact taggttactt gaaaatggaa aaaaagatta ttctgtggta tttaagaacg
      661 gaaaggtaac tgattacaac gaaatatttg agaaagtcat tgaataatgg tttttctatc
      721 tttttattaa ctaccctacc ccgttgtttt ttgaccgtgt ttcgagagga atcattagaa
      781 agcataggct aactaggggt ttctttttct tttatttttt gggaatccgc ttaagtgaaa
      841 tgtatctgaa atgaaacgga gataaagtga ttttttgctg taatgacaag gttttagctg
      901 tttcagatac catgtaaccc aaaatagttt attgagaaaa taggagagta tttgatacta
      961 actagtaggg aaaaatgaga taaaaagtaa atggaatcat ttcaggtaat ctgaaataaa
     1021 aaaatataca gtcctgtggc actttaccta tgggactgta tattttttac tctcagcgtt
     1081 ttttgactcc gtgtctgact ccgttttatt gattttatat gttattcagt gaccctttaa
     1141 caggtcaatt tttatgtttt tgtcttcgta tgactcagtt tgatacctag tgatttccat
     1201 ggtaatacgg gatgttgaac aagctagaga agttctgcag gggttaattg caaacaattc
     1261 agataaacaa attacaatag attatttcaa gagggaaatt aaaaaatcag aggaaaaata
     1321 tttagattta aagtcggata tcctattagc agacgatata ggttcactaa ctgtcgaaga
     1381 agatagccta ttctacgtct attgtgcatt gacttcgtaa aagaagacgt cttttccagg
     1441 tatacagttc ttttatctac ttcatatgaa aatttgggta caaacgacaa ggaagtcagt
     1501 tttctggtca gactatcgta cgaacatctt gttgtggtat ttacactcag ctttgatgat
     1561 gagtacaaga gtttttcagc gaacaagaca gaacatcgaa agaggtttcc agacgaagtt
     1621 ttacaggctg ggctgaagta ttatcaagaa ggactcacca ttaagaagtc tttatcgaga
     1681 atataagaag atacaggtat agaagtcagt cggtcaacat tctgtgatta cctaaacagc
     1741 aaggagtaac aggtgaacgg gaaaaagagc acagggaggg ctatgttcac tggctgaaga
     1801 agcaagataa acctgtttat gacttgttct ttgaaataaa gaaagcttta gatagtcagt
     1861 cattagagaa cttcattgat gggtatgatg aaaagttatc taatgagcaa atgattgcga
     1921 taatgaaaga ggtgtttcgt cagtatgggt tatcaaataa acgtaggaaa gaggtttttg
     1981 accacgttaa gacaataatg agcttttacc acacgaccct cggctaaatc taaagagggc
     2041 gaaaaaggga cgagtggtaa aatttaatgg gaatagctaa aagtaaataa taataagtca
     2101 aagactgcct agtttggtgg tcttttttca tgttcataaa aataaaatag gacagacgaa
     2161 catcttcgct aactcccctg tgttgcaaga ggcaaactct ataattctcc agttaagcta
     2221 tattttgttc tttattttga gatagaggaa aaaacaaaaa tgtgttaaaa ttgaacataa
     2281 gcataattag aaattgtcga gttttttcaa gtaaaaatct tgacttgtaa ggaggaaaag
     2341 ggcatgatga cacgcaatca cagtactagc cagcagtctg cccaaaagcc catatatgaa
     2401 agtgataacc gattcgtagc atccgtttcg gttatttgtg ttgggaagat gggtgatttt
     2461 tagtggttga agatatggtg atggttgaag aggaacaagg acgactaatc aaaagtaaaa
     2521 aacgtgtcca gaagcacggt gaggtattta caccgcaaag aactgtcaaa gatatgttgg
     2581 atttgccagg cataaaagag gcttgcgagg agctgcagac gactttctta gagccttcag
     2641 ctggagaagg tgctttctta gttgaggttt tgactagaaa aatggcaatg gttgctcgtg
     2701 aatataatga gtccctagaa cagtatgaaa attactcctt actggcgctt tcaactctat
     2761 atggcgtgga gttactcgaa gacaatgctc agacctgtgt aatgaacatg tttcaagtat
     2821 tcaacgattt gtacagagaa caatcgaaaa aacatggtac cgcaatgaaa aggaaagtcc
     2881 aagacagtgc aaagactttg atttctagga atatcaaaca gggagatttt cttacaaaac
     2941 gaacaccaga tgataatccg attattttta gtgagtggac acctaagacg ctaagaaaag
     3001 gacagaaaaa aatcactgta aatcgaactg aatattcttt ggaggatatt tattcagggg
     3061 taacacgaga gtttggagag gcatactcag ctctgcctgt atttgaacag ctcgatttgt
     3121 tttcatttga tgacgaggtc gatgaagaag tttcaaatga tccaatatta cgttatgtag
     3181 cgatgccgat aactgaggtt tataaggaag agatggagga aattgatgac gacagcgttg
     3241 aaatctaaag ctaaatactt cgattactta cctaaatatg gttctaagct agaacacttc
     3301 cttgggattc ctaatttagt agatgcaatt aacacgtacc gtgtaaccgt taatcaaata
     3361 cctaatgaag ttgctattgg aactagacgt tattcggagg tagcagcacg gaagattgct
     3421 tcaaatgtgg gtattgacca gcaaagtatg aagtatgttg atgtacttcg cgagcttagg
     3481 gtcagaaata atattactcc tacgatagct gacttatttc ataagttgag aaaatatgga
     3541 aatgttgcag cacatgaaaa tggaattata cctgtttcag aggcggtcga atctttagtt
     3601 actcttgata ccttgctaag agtctttgca cgcaatctgt ctggggataa atcgttaaac
     3661 ccaaaggaag aaattacgga tgagatgttt gttatcacct ataacacctt tgaccgtaaa
     3721 cttatttaca tccagagtgc caaggatgct gacggcacat ggaaaatgta ccaaggactg
     3781 gaaaagattg gggatgcatc agtaccagag aattatgagg cagactttac tcctaatagc
     3841 gagtatttaa gagagtatgc aagtagaaga ataaagcagt acatgacaac agcgggggta
     3901 ccttttgtcc ttcattgggc gcaattggct gttaataaga agaaccaatt tttccgtgac
     3961 catgacgtgc atgaagtatt aaagcgttcg ggctataatc ctcaaacgat tggcgaagat
     4021 gacacaggga agcctaatga gtggttcagt gtaacagttg acgttgccaa gaaagcaatc
     4081 caagcggtta aagatggtaa aggtagtctt gactcagaaa aagatgactt tgacgagttc
     4141 aaaattaatt ttagaccaga acaaaaagat gctattgagc agactaagac tgtattcaaa
     4201 acgaaagatg agatgctttg gaatgccaag atgcgttttg gtaagacgct ttcttctctt
     4261 caagtgatta aagagagcca atacaaaaaa gttcttatca tgactcatcg acctgttgta
     4321 agtgatggtt ggtttacgga tttcaaaaaa atcttcacag atggttcgta catctatggt
     4381 tcaaaacaag atggagaaaa gattcaaaac cttgttgata ccgaaaaacc tttcatctat
     4441 tttgcaagta ttcaggactt acgcggttct gagtgggcag gtggaaaagc aggggataaa
     4501 aactatgaat tcttagcgat tgactgggat tttattatta ttgatgaagc tcacgaagga
     4561 aacgaaacgg aattagctaa taacgtaaag gctaagttgc ggaaagagca taccaaggtc
     4621 ttagagcttt cgggtacacc atttaacctt ttcgataagt atgatgagga taatattttc
     4681 acttgggatt atactatgga gcaagaagct aaggagaaat ggtcagtaga gcatcccaat
     4741 gaacctaacc catacgaagg tttaccgaaa gtatctatgt tcacctttga aataccaaat
     4801 aaatttgatt atttcgatga aaataaggca tttaacttcc gagaattctt tagggttaag
     4861 gaagatgatg aaacaaagtt gcttcatgaa ggtgacgtac gcaagtttct tgattatatt
     4921 actacaaacg atgaaaagac taattttcct ttctcaaaac cagagtttag agaaaactta
     4981 cggcatactt tatggctgat gccgggggtt aaagaggcaa atgcttttga aagagtgctc
     5041 gaaacgcacc ctatattcaa agattacaat attgcaaacg tagtcaagac aggtgacagt
     5101 gagcatgcta gtgattcaga tttagaattg gtgcgtaaag ctattggtaa tccagctaag
     5161 tctaagacga taaccttaac agttcgcaag cttacaacag gagttaatgt tccagagtgg
     5221 acaggggtat ttttcctttc aaacacagaa agtcctacat cttatctgca ggcagcgttc
     5281 cgtgcacaga caccttttaa ccatgcagag cttggaatta agaaaaactg ctacatcttt
     5341 gattttgcac ctgaccgtgc tttaaaaatt atgagtggaa gtgtcggact aactagcaag
     5401 aagggaaagg ttaatagttc agagcaaaag aaaaaactag agcgcatgct aaatttctta
     5461 cctatccttg gtaaacaggg gaatgtgatg aaagaattta gcgttgaccg aatgcttacg
     5521 gcactgaaga aggcttatgc agaaaaagct gtacggactg gctttgaaga cagctctctt
     5581 tacaatgaca acctattaaa tttagaccaa gctgatctta ccaaatttga agaccttaaa
     5641 aaaattgttg gctcaagtaa accaaccaaa gtgaaagact tcattgtttc agataacggt
     5701 atgagtgaag aggagtatga aaaagcttcg agggcagaaa agaaaccaaa acgtcaacgt
     5761 accaaagagg aacaggaagc aatagatagg gcaaagaggc ttcgagagca gcgaaataaa
     5821 atgatttcca ttttgagggg cgtttctatt cgcataccta tgatgattta tgggatggac
     5881 attgatatta aagatgacgt tactattgag atgtttctta atttggttga tgaggcttca
     5941 tggaatgagt tcatgccaga ggggttaagt aaagggcgat tcagagagtt tattgagtac
     6001 tatgatgcag acgtttttgt ggaggcagga cgcataatcc gtagacgtgc aaagtcttat
     6061 gatgagttag atgttattga acgtactagg aaaataggtg aattatttag cacttttaaa
     6121 aatccagaca aggaaaccgt attgactcca tggcgagttg ttaatatgca ccttggtaac
     6181 actatcggtg gactttcctt ctttgatgaa gaataccaaa attctacgga gaacggtcaa
     6241 ccaatcgtgc gatggaggaa aactgactgt acagatgata tttttaagga aaatagaaag
     6301 attcttgaga taaactcaaa aacagggcta tatcctttat atgcagcaac gagtatgtac
     6361 tatgttcagc tccttaaaca aagcgatatt aatgctggaa gggtagattc agaggcaata
     6421 tgggaaaaag tattatcaga gcaaattttt gtcatttcta aaactccaat ggctaagacg
     6481 ataacgaaga ggactttgat tggttataac gcatggaagg taaatgttga atactcaagt
     6541 gaattagtta cgagtatgaa acgttcaatc aatgacggtt taacgaattt gaaaggagtt
     6601 tataaaaacg tgaaatttga tgtgataatt ggtaacccac cttatcagga gaaagatgga
     6661 ggttcaggag ctagtgctac accgctatat aatctatttg tagaaacctc tgttaagtta
     6721 tcagaacgct atgtttcgat gattactcct tcgaagtggt ttgcaggtgg taaagggtta
     6781 gataagtacc gtgactttat gcttaacagc tctagcttga aggtgatggt ggatatagta
     6841 aatgggaaag aaatattccc aaacaccagt attggtggcg gtgttagcta tttcttgtgg
     6901 gataagaaat ataatggatt gacacagtat actaatcaac atgatggtgt atcaaataca
     6961 caagagcgaa aaatgaacga gtttccagtg tttgtgcgat ataatgaagc catttctgca
     7021 attcacaaaa ttggggaaca cgctagtgtt ggtgactttg ttatatcacg taacccattt
     7081 gggcttccaa cgaaaattcg aggggaagaa gtgcaggatt ccagaaattc aataaaagta
     7141 atctctagtg gtggggtagg ctttgttcca ctggaagata tcactaaagg acaggatatg
     7201 gttggaaagt ataaagtcat tagtagctca ctgactagcg aacatgcagg tgaaccgaac
     7261 aaaaatggta tgtttaaggt gatttctact aacagagtta ttaaacctaa tgaagtagtt
     7321 acagattcat acctagtgct attttctgct gataccgaaa ccgaagcaat taattatctg
     7381 aagtatttac gaacacgttt ttacagattt ttattacttc aagcagtgac atctattcac
     7441 ctatccaaag ataagttcat gttcatacca gtacaagatt ttacctcagg ttcagacatt
     7501 aactggaatg taggtattga agaagttgat atgcagttgt tcaagaaata ttctttcgat
     7561 gcaagtgaga tattgtttat tgaccaaaca atcgtcccga ttcttcacga ggaatattac
     7621 taagagaaca agctaacaaa tgaggcttag aaccctgttt tcttgattaa ttgccccact
     7681 ttaaatcaag atttaactgt ctattatcaa caggtcaagg taaaataaag gatgttagca
     7741 agtaaagaga ttgatttgag tctacatcga acaagggaat aatccaataa aaaatgattt
     7801 aga
//
LOCUS       DAFKHN010000108         7570 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFKHN010000108 DAFKHN010000000
VERSION     DAFKHN010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.108"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            8..1996
                     /locus_tag="LY912_002566"
     CDS             8..1996
                     /locus_tag="LY912_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBM6956204.1"
                     /translation="MQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLFVHKSYFLVAA
                     FFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLLLLISNRF
                     WYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVLLIVGGLI
                     LLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSPSFLLFNL
                     FKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYNTKADEIN
                     QTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLMLSVGYGG
                     GTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHPFTAALYR
                     RKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNTETSQFIQ
                     LSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKFIQEIDKI
                     DKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNKEVVAPNN
                     FGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTEDSQIIQE
                     KNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(2056..2772)
                     /locus_tag="LY912_002567"
                     /pseudo
     CDS             complement(2056..2772)
                     /locus_tag="LY912_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
     gene            complement(2999..3541)
                     /locus_tag="LY912_002568"
     CDS             complement(2999..3541)
                     /locus_tag="LY912_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBM6956205.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(3546..3773)
                     /locus_tag="LY912_002569"
     CDS             complement(3546..3773)
                     /locus_tag="LY912_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBM6956206.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(3852..5732)
                     /locus_tag="LY912_002570"
     CDS             complement(3852..5732)
                     /locus_tag="LY912_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBM6956207.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(5921..6535)
                     /locus_tag="LY912_002571"
     CDS             complement(5921..6535)
                     /locus_tag="LY912_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6956208.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            6677..7237
                     /locus_tag="LY912_002572"
     CDS             6677..7237
                     /locus_tag="LY912_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6956209.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
BASE COUNT         2312 a         1510 c         1237 g         2511 t
ORIGIN      
        1 attttatata caaaaaatcc gtttcattca tcgtttcatc gaatacttcg cttttgattc
       61 gattgaacaa ttaactcagc gttggaaaaa aagaattcat tggctttttg ttcataaaag
      121 ttatttttta gttgcagcat ttttttactg ctttaccttc gtgcagattt tcgttttaga
      181 accaaaagaa ggttggaaag aaactatcca ggttgcctta aaaatattta ctcagcgaca
      241 agcacccatg atcctgacaa tcatcattat tatgggattt ttcttcttac tattgttgat
      301 ttccaatcgt ttttggtacg ccttgactgc taccttgatc attaacttac tgctcactat
      361 ttcgacagta atcaaaatgg aaatgcggga agagcctgtc tttccttcag atttaaaaat
      421 gctgaccgga ttgtcagaac tattatcgat ggttagccca gtcttattaa tcgtgggcgg
      481 attgatcctt ctcctattat tgattactag tattattgta caacgtagac tacaaaaaca
      541 gtattccttg aagattcatt ggaaacgtcg atttatcagt atcgctgtat tattaggatg
      601 tttttcgggt gtctttttca ttaatcacaa aaattcgcct tctttcttgc tgtttaattt
      661 atttaaagta aacaagactt tctttaacca gcaaggcgcc gtaaaagata acggaccagt
      721 cattcaattc ctaaacaata tcgacattaa aatcatggaa gaacctgctg gctattcgaa
      781 agaaaaaatt aatggaataa tgaaaaagta caacacaaag gcagatgaaa tcaaccaaac
      841 aagaagtgac tggttaaaca atcagacgat cgttctcaat ttaagtgaaa gcttcagtga
      901 tcctgcacgt gtccctaatc tgacagtacc tacagaccct attccttaca tcaaaagcat
      961 tataacagaa ggaacaggag gattgatgtt atccgtcggt tatggtggcg gaacagctaa
     1021 catggaatgg gaaggactga caggcttgag tatcagtaac ctgtctgctt cgttagttac
     1081 accttatacc cagctagtgg agcgtcagaa aataagtcca aatattaccg atctattcga
     1141 tgaaaaaata gccatccatc cttttacagc tgctctttat cgcagaaaac aagtgtttga
     1201 taaatttggt tttgacaggt tctattattt agacagtccg gataaattaa cttatacgga
     1261 taaaatagaa caaagcccac gcatatcgga tgattcagca tacaaagaaa ccttgaaagc
     1321 tttacaaagc aatacggaaa cgtcacaatt catccaatta tccactatgc aaaaccatat
     1381 gccttatgat gattactata gtgaattgaa ctacactgct gaaggaactg ctgtcattcc
     1441 taatagaaga aaagaattac aaacttatat gcaaggcctt cactataccg atacagcagt
     1501 aaaaaaattc atccaagaaa tcgacaaaat cgataaaccg attacctttg ttttttatgg
     1561 tgaccattta cccgcaatct atagtgggaa tgattcgaaa aaatatggat tagaacagca
     1621 ccagacagat tatttcattt ataacaacaa gtatagtcgt gaacaagcag ctacgttaaa
     1681 taaagaagtt gttgctccta ataactttgg tgctatggct cttgagcatg cgaatatcaa
     1741 agtaactcct tactatgcgt tgttgacaga agtatctaat catctacctg cattaacaat
     1801 tgatcctaca gaaagcttgt ctaatcgttt taatggaaaa caggtctttg ttacagagga
     1861 tagtcaaatt atccaagaaa aaaatttaac tgagaaacaa aaagaaattc tagaagatta
     1921 tcgtctgata caatatgatc ttgttgcagg taaccagtac agtgcaacat gggcgacaca
     1981 aaaaataaaa gactaacaaa taaactgagc aaggggttgt gataaaagac atgtcacaac
     2041 cccttgttta tctcattaat ttgcttgtcc ataaacgatt tgattaaagc catttttcaa
     2101 ttcattattc gctgtctcgt tgaagtaaag ataattatcg ggattcccct gattttgttg
     2161 tgtcaccaat acttttggct gattttgctg aaacccgaat agatagacgt gctttttcag
     2221 ttatggttct gtctctgcat cggaatagac ggctgtgatt tgatagtctg cttgacctgt
     2281 cccactttct gaccattctg cagaaacagg cactccacca atagccatct tccactcccc
     2341 gttcaaaata gcttgaggga ctttaagacc atataagtcc acactcattt gattcgtata
     2401 acttttgtat tgttgtccca ttgtttggcc ccatttggtc ataaatgcct ctaattgtgc
     2461 ggatttgtct gcattccaca gtgtttgttc aacttgttcg ctgctttctg aagaggaaga
     2521 tgaagcctct acagaagaac ttgaagtaga tgtttgagtt gtttcagtcg ttttggaaga
     2581 ctctgacgaa gtagaggtat ctgctgtttc tgtacttgct gcagttgact tgctctctgt
     2641 gctagttgtt gtagtagttg caactgttgc tttcgctgtt tcttttgttg attctttttt
     2701 cgattcattc ccgttggtac aaccagctaa caaaaaagct agaccaattg ttactaaaat
     2761 cctttttttc aattaaaaaa ctcctttcga ttactcccac ttctttattc tatcaaataa
     2821 gcaatgtgat tttattgatt tttcgtattt tctcatcaat ctttcaaatc ttctaaaaac
     2881 tgagaagcac ccgctgatgt tgtctgtaat acatcagcgg gtgcttcttt tattttaatc
     2941 ttcgtgattt tccaatttac ctcacgcttt atatttgtat ttgaagaaac atagactttt
     3001 agtcatcatc gtcttcctca tccaaatctt gtcggacagt ttttccttgg agtctttgta
     3061 cttggtagat gatttcttta ttgaaactta aaagttcaac aagcaattgt tgcaagccat
     3121 atttttcttc tttttcagct aatttgattg cccgtgtgat aaagacattt tggaaatcaa
     3181 aatcttttgc aaagttttcc aacattgttg aggctggtaa atatttgttt tgaccatgtt
     3241 cgtaaatttt tccataacgc atgacttctt ctaaagtaga cggaacgatt tcattttcaa
     3301 tcactaactc atgagagatt ttattgaacc atctcgcttc ttgatcagca tattctgaaa
     3361 aaagggtact taattcttgc gaagatgtac ccaaaacata caattgtgct tggatcaatt
     3421 tcatttcttc taatttaaaa tttgctaata catgccccac catggcgcca gcagttggtt
     3481 tatgatggtc gatatctgct tgttttgttt cttgaacaaa tttttcttcc actatattca
     3541 ttgatttacg cctcttttac ttttgctgat tggacttcat aacctaattt ttccacaact
     3601 gcagctaatt gttcagggtg gacttcatct ggatcaaagt ttgctttgat tttgctcgca
     3661 ttaaacaaaa ctttcgtatt gcttacccca ggctgttgag aaaccgcatg ttcgattttt
     3721 tgcatacagc ttggacaagc tagtgtatct aattgcataa taattttttt catcgtagtt
     3781 cttccttcct ttttcttgat agtcttattc tagattacag cttccataaa aaaattgatt
     3841 cttatcaagt tttacgattt ttcttctttg ctttcgtgtc caaaatacaa taaacgcatc
     3901 gcgttaaaga taacgatcaa gatactagct tcgtgaacga acatcccact agccatgtaa
     3961 ataaacccgg caaataagcc gttgagtaaa aataagacga caccaatggc aatcactaca
     4021 ttttcacggg tatttaaaac agttttctta gccaagcggt aggcatgaac caacgattca
     4081 aaattagatt gcatcaagac aacgtcactc gtttcgatag caacatccgt tcctgatccc
     4141 atagcaatcc cgatatcagc cgcagccaaa gagggagaat cattgattcc atctccaata
     4201 aaagcaacgc gcaatccttg ttcttggtat tttttcacaa attgaacctt ttcgtctggt
     4261 aataattcag catggacttc atcaatgcct aacatatcag ctacataatc agcagtcatc
     4321 tgattatcac ctgtcagcat cactaactgt tttgctcctg cttgtttcaa cttagctaat
     4381 tgttcagcga cttctggtcg aatcacatct gacacaccta tgatttgagt gatttttttg
     4441 tcgattgcta caataatgac cgagctgcct gtttgttgta attgatgtaa atcttgtact
     4501 tgctttggtg tgagagaaag tttgtgagcg gcaatcaatt tggtgttgcc cgcacaaact
     4561 gtatgaccat caatctcagc tgtgattcct tgtcccttga ttgtctgatt atctttgact
     4621 gctaattgtt gaaaatcaat gtctttctcc tgagcataat ggatcacggc gcgccccaga
     4681 ggatgatcgg ataacgtttc taatcgagcc actaaagcta agctgtcccc ttcatcctct
     4741 gtatagttct tgatagtgga tacagcagta gttcctttgg tcaatgtacc agttttatca
     4801 aagacaaaag tatcgatttt ggaaaaagta tccattgctt caccgccttt gactaagatg
     4861 ccccgtttcg ctccattacc gattcctgct acattcgaaa caggcgcacc aatgactaaa
     4921 gcgccaggac aaccaagaac caaaacagtg attgctaaac gaaaatcacg actaatcaga
     4981 ccaacaacca acgcaataag taaaacggtt ggagtataat actgagaaaa tcgatcaatg
     5041 aatttttccg catgggattt ggtatcttgt gcttcttcta ctaattcgat aattttggca
     5101 aaggtcgtat catctccgac cttagttgct tcaatcgtca cgtagccatc tgctaaaatc
     5161 gttccagaga agacttcatc tccactgatt ttgacgactt gtcgtgattc accagtcact
     5221 gcggcttcat ccgcataccc tttcccgtca atgactcgtc cgtccacagg aatagctcca
     5281 ccagttttta ctaagacgat atcgccttct tccacgtcat cgatttccac ttcttcagtc
     5341 gttccatctt cttggacaac actagcagta gatggggcca tctcggtcaa agccttgatt
     5401 gactcccgcg ttttggtcaa tgttttttgt tccagatagc taccaaacaa aaacaagaat
     5461 gtaacgatag ctgactcctt gtattctccg atcataaagg caccaagcac agcaatagta
     5521 acgagtaaat caattgagat aactttgact ttcactgcct gatacgcatg gatcataata
     5581 ggtatgaccg caataataga agctatggct agagcaatgt tatagaacaa gacaaaacca
     5641 gtaaattttc cgataaaacc aaaaataatc aacacagctg ataaggcggt gatatgattt
     5701 cgatgctctt ggatccactt ttgtaatttc atctttctcc ctcttttcct ttcattctta
     5761 cgagactaag tatagatact tatccatcat aaaaaattga ccactatcaa gtttagtcaa
     5821 aaaggcggtt ttcttttggt agaatacact acaaaaaata gttagcaaga agactcacta
     5881 aaagtgatct tgccaactat tgtcgtttct atcgaaattt tcattgaatg attttcctgt
     5941 acagcataca tcggagatct atttctttat ctaagatttt tatcttgcta attttttcct
     6001 ttagtctttc aaatccacgt cgttcataga attgatacgt acagccacta tctgtaaaaa
     6061 ggaatatttc ttttcctttc tctctttttt caaattctgt tagcaacttg gtaccgatgc
     6121 cttttgtttt caaatcagga tttgcagcta aaaaaatgat ctctccatct ggcgaatgct
     6181 tctttaaata tgctgcaagc atttgttcat ttgctgtctc gtaagctcct ttactttctt
     6241 tagcaaatat attttgtaaa aaatcgaata tcttaacata tatttgctgt ccaaaagaac
     6301 gatgtttctt tttttctcct tttatctccg ccagcaaaac acctgccaac tcgtcctctg
     6361 catacaaagc aagaatttga gttgctcgat tcaactccat atacaaaaaa tatcttccgt
     6421 aaagattcag cagaagttca ttttccatat atctctcaaa gttcattcct tcaacagcaa
     6481 aatagatagc ttttttgtaa tctttctttt ctaagggttt aaaagttagt ttcatcattt
     6541 cgcctcctca acttcaatga ttgtgttata cttacattat aatagacaca gtgtctacta
     6601 tctataatca atcatctata agtttgtcga ttaagcgaca gctttgcttt gatatgtcgg
     6661 ataaggagat aggtaaatga aaaagacaga tagacgcgtc aaaaaaacag aaaaagcttt
     6721 ggctgaaaca ctatccacat tattagtaaa taaaaagatt caagcaatca ctatacgcga
     6781 actaacagaa acggcagatg tacatcgttc gactttttat acacattata aggatatcta
     6841 tgatctatat gatcaattag aaagcaactt ttttcgggat ctaaatgaaa ttctctctta
     6901 tgatccagcc catagctatg aggaactata cactcgcttg attgactatg tttacgcaaa
     6961 tactttttta tatcgcttat ttatcctcaa ccatggtgat atttcgtttc agaagaaagt
     7021 taaacaagtt attgaagaaa actatctgaa catatggcta tatgaagaca agaaaacgat
     7081 tatcacagaa gaaatgagat tctttactac gtaccacgtc caaggttgtc tatccgttct
     7141 caatcggtgg gtagaaagca attacaagta ctccaaaaaa gaattattag aactcttaca
     7201 gaaactgaat gatcacatag agaaaatcat gccttgaata aaaacatact aagcttagtt
     7261 aagaagaacc gtaaccttct cgtataacaa ctgaatctta tttagccaaa ttgtttactg
     7321 aagatttttt gagtaaaatt tctataattc ctacttattg aaaagtagtt tgtagtgctg
     7381 cttctccctc tctaagtgat atatcttgtt gtaccaatca aattcacctc atcattaata
     7441 aattactttt aggctaattt attacaactt ataggttgaa gctgtaacca atttatagtc
     7501 atattatatt tttatcatcc agtttattga attcttctcg tttacctcaa ttcattttaa
     7561 aggggaatca
//
LOCUS       DAFKHN010000109         7276 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFKHN010000109 DAFKHN010000000
VERSION     DAFKHN010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.109"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(170..3319)
                     /locus_tag="LY912_002573"
     CDS             complement(170..3319)
                     /locus_tag="LY912_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBM6956210.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3333..4550)
                     /locus_tag="LY912_002574"
     CDS             complement(3333..4550)
                     /locus_tag="LY912_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBM6956211.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4540..6135)
                     /locus_tag="LY912_002575"
     CDS             complement(4540..6135)
                     /locus_tag="LY912_002575"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBM6956212.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYSISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            6260..7045
                     /locus_tag="LY912_002576"
     CDS             6260..7045
                     /locus_tag="LY912_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HBM6956213.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
BASE COUNT         2128 a         1477 c         1198 g         2473 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcagattag
      361 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaaggcatga atcaaattat
      421 cacttgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
      481 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
      541 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
      601 ttcctagtaa ttgatcaata taagtagaat caatatcata caacttagtg gtattttcac
      661 tataaaattc gatcgttgaa aaatcttctc cctctttttc tggttcttcc tccatcaatg
      721 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
      781 aagttgaaga ttgcaccatg tcatcattgt aatcatcata agtcactaac gattcatacg
      841 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
      901 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgc ttgaatcttt
      961 ttttggattc ttggtaactt ggataaatca aacccgattc ttctttagct tctgaataca
     1021 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg ctttcggaaa gtaacaatta
     1081 gtccttttgt tttttcagga tacgtacggt tcgtacgtga aaaggcttgg atcaatcctg
     1141 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtca
     1201 atagacgatc cactacgatt actaaatcga tttgtttccc aaattgtttg aattccgctc
     1261 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctagtgacc
     1321 aggcagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     1381 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt gggaaatcag
     1441 gatcctccat cgttcgtcct tcacggatag gctgattggg aaactctttt attaaccaat
     1501 cagattcttt cgtcatctct ttgatggccc gataatactt tttggccata tcaatggaac
     1561 tcgtggttaa gatcgcagac ttcgttggac ggccatttcg aaaatcaaat tttgtatagg
     1621 cattgtctgg acggaacatt ttatgaatga ctttttggat atgttcctct gcttcaaaaa
     1681 cagtagggtc caaataactt tcttttttga cagactccat ttgatcgatc atacgattga
     1741 tctgttccgg tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     1801 tctctaatga agtcggctcc acggtgtttt catgctctac ttgaaatcct aaaaccgagc
     1861 catcttctaa tgcattcttg atggtatagg tgtgcaagac ctctccatac tgatcatggg
     1921 tcgtacgtgc caattgccct ttggcttgtt tccgattctc agggaaaatc ggtgtacctg
     1981 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     2041 ttaacgctcg atgacactca tcaactacaa acacgatatg ttgccccatt aatttttgga
     2101 agcgattggt tccttttttc tcttcctgtt tctttgcata tttcaacgcc gcatctagtt
     2161 tttgacgggt tgtaatgatc acaacattcg cattggcatc tgccaacaga gtttcactta
     2221 actctttggc acttcctgtt cccacgatca agctattcgc tttggcatta ccagaagaaa
     2281 ccccagtatt aaactccgaa gcaaatttcg taaactctgt ggtggtctga ttatctaaat
     2341 ctttgcggtc cactaacatg atcgttcgat cgatccccga ttttcgtgct aaaagcttag
     2401 tagatacaaa actagtcaac gtctttcctg aaccagtcgc atgccacaca taccctgatt
     2461 gatgtttatt tgcggcaata aacaaggctt gaatcgcatg cacttgataa ggatgtaaca
     2521 ccatgagggt tttattgtct tgatcttcac tgacaatcgt ataatccgca atcaagcgat
     2581 gggcatctgg gatatttagc acttgtttgc aaaactcata taagttttct acctttttat
     2641 tatctttcgt tcgccaacta aataaaaact taggatgcaa atccttcggt aaggcatttg
     2701 caaaataccg agtcgtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     2761 tgttccgaaa catgccttct tcagcatatt ttttgatttg attaaacgcc tgataaaaac
     2821 catcttttgc agttacttgt tttagctcga tttggataat cggtaagcca ttgatcaata
     2881 aggtgacgtc aaaacgtcga tcccgcgctt ctatgttact tccacgtttt gcaatttgat
     2941 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa aggataagtg
     3001 agacagaacc caattgcgga ttttcccgtt caatcgtgat ccgagccatc ccattttcac
     3061 cttttaacca tttcgcagca tcaaatgggg ttttcgtccg tagcaataat tcggttttga
     3121 tcgtttcaaa ctctttatcg gtcaaaggag aatcattcag ttctgcttga ttatttgaga
     3181 tgattttttg acgtaaattg ctccaaagat cttcttctga ttttagatcc ggacgatacg
     3241 tccactgatt atgtccttcc ccgaggacac gaatcaactg ttcttcgact tccgcttcct
     3301 cacggtgact aattttcatt cttcttccct ccctaaacaa acatcttttg caagaagcct
     3361 tttttcgttt ccttcagcaa atctaactta cgttgatgaa gagcgatcgt atcatctagc
     3421 tgcttgaaga aggcaccaat tttttgttgt tcatttatat ccggtggaaa ctgaaatgtc
     3481 ctttgttcta taccaccttt agtcacatgt accattgtcg ttccgttagt tgattcttta
     3541 attttctctt tatcagtcaa tagccaagta tatagatact gtttgtccaa ttccttagat
     3601 aaaaatttaa gtttccaaat atgataatgg tagattacac gttcttcatt ccacatttca
     3661 ggaccgaagc ttgttgccca taaatataag agatctcctt tattagcata cttgtcttcc
     3721 tctaattcta agtttgaata ataccatcta tcattagtat taaaattacc tactcttaaa
     3781 accctatatt ttccagaatc aagtaattct tgttgtttaa aagctctacc attcaaaaaa
     3841 actaccactt cccccaactt ccgctcttcc caatctcccg taaatcctgg aaaacgaact
     3901 tctggcactt ttgctccgtt tttagggaac attttttgta agaatccttt tttcgtttcc
     3961 ttcagcaaat ctaattcgtg ctggtgaagc atgatggtgt gatcaagttg tttgaaaaat
     4021 gaaccgatct tgatctgttc gtcataagtt ggaagtgaga taggtgtctt tttaccacta
     4081 tcaattgtat aggttccgac ggttccaatg cctgcaacgt cacggatata cttctgaatt
     4141 ttgttattta tgaacgagta gtaaaagaag tttccgtcaa ttttatgctc attcttgaac
     4201 caaatgatgt ttccatcctt aaagtaaatt gggttatcat cagtgattaa taaggggaca
     4261 cctattgatc cgacaccagt tacaagcaag tctccttgag aaactttacc tgaatttttc
     4321 gaatattcat tatatttttc ttctgaaatg taaagataat cggatggttc ctcatttttt
     4381 gcagctgaga caatatcacg agcacgtaaa aatctaatac ctgagttagt ccaatctgat
     4441 tgatgaattc gcttcacaga agtaacatcc atcatatctc ctaacttacg ctcttcccaa
     4501 tcttccgtaa aaccaggaaa ccggatttct ggtcgtgtat cattgctcat gtttgaacac
     4561 ctccagcgca ccttgtaacc acgcttcatt ttcaggtgtt gtttgcaggg aagagatagc
     4621 ttctaaaagt tctttttcta gcacttgctg ttcttgtcgt atcttcttga tgtcatttcc
     4681 gacatgaacc atatcaattg gttcttcttc ttcgaaagta tcgacatagc gtgggatatt
     4741 taagttatag tcattttctt tgatttcatc aaaggttgcc aaatgagcgt atttctcgac
     4801 atcttttctt tcagcgtagg tttcgaggat tttttgaatg ttttcttccg ataatttatt
     4861 ctgatttttc cctttaacaa attcacgact agcatcaatg aataatacat ctcgagtttg
     4921 acgattcttc ttcaatacaa tcaccgtcgt tggaatcgat gtaccaaaga acaagttcgc
     4981 aggcataccg atcacagcat aaatactgcc gtcttctaat aatttttgac gaatgacccc
     5041 ttctgcagca ccacggaata aaaccccgtg tggcaagacg atagccatag tccctgtttc
     5101 cttcaaatga tagaaaccat gaagaagaaa cgcaaaatct gctttggatt ttggcgctaa
     5161 tttcccgtag cgattaaacc gagaatcatc taagaaggtc gtatctgctg accaattagc
     5221 cgaataaggt ggattcatca ctactgcatc aaatgtgtaa ggttcatctg ttggccagtc
     5281 cttattcaac gtatccccat tgcggagatt catttcttcg gcatctaccc catgtaaaat
     5341 caagttcatt tttgctagat tgtatgtcgt tgtatttagt tcttgcccat gatatttaac
     5401 gttatctgga tgagttaagt agttacgtac atttaacatc aaggaacctg aacccatggt
     5461 tgggtcaaag acactaaaga atcgtcgttc tttttgatcc aacgtcacga tttgtgccat
     5521 catatcagaa accatatgag gcgtgtaaaa ttctccggct ttcttccctg cttctgaagc
     5581 aaattgactg atcagaaatt catacgcatc cccgatcaca tccccatcgt gacctaaaac
     5641 ttccacgtca ttcaatttct tgataacttc ggtaatcgtc acatttcgtt gttgctcatc
     5701 tgttcctagt ttttttgatt ggagatccac atcatcaaat aacccattaa attgattgta
     5761 ggtagatgcc aattgcacaa aggctttgtt tagatcgttc aattggaacg ttgcttgttt
     5821 tgcttgatcc gctaagacgt tgaaaagata ctctggtgag atcgaatacc ccaaaatatc
     5881 aacgattgtg gcaatcaggt cttcttttga ttcttcatct gaaagtaatt cacgatacaa
     5941 cattgtttgt ttgcttactg tgtcatattc ctctaaggat tcatctgcta aaagaaccac
     6001 ttgttccaac aaacggtcgg ataaatattt atagaaaatc agtcccaata aataattttt
     6061 atattctgac gcatccattt tactacggag attatctgcc gcactaaata atttttgatt
     6121 taattctgca cccaaaaaga tacactccta tctcttattt aaagttgcta tataccctct
     6181 tattttagca tactcccttt tagaaaaagc aaaaaaaaaa gaaaaaatct tattcttgat
     6241 aacaagctac gtgacgtata tgcctaacaa aaatagaact tttgaatcaa tcttaaatga
     6301 aggtttaacc acagaaccgg catccattat ttttgatgaa gttatcgatg acgttgaaga
     6361 tagtaagtat cataaaaatt taaaagaact tttttatttt gcactcaaca atggaccaag
     6421 tttgttcact ggtatatcag tacctgatag tgataatcca ttaattatgg caaaaattta
     6481 cttaacaaaa tggtgtaata aatacatcag ggataggaat aacccagcat taaaaaaacc
     6541 tcttaaaaca tttggcgaaa aagatgctgc tttaactact agagtagcag caaatgctaa
     6601 tattgatgat caaaaagtat tgaatgacta cttgcgtgga cattttttat atatgagcgc
     6661 tgagaacatg aacggaagta ttttagagga atatttagcc gaagtgttag aacctgaagg
     6721 ttggatttgg tgcgccggct ctgtatatcg agctgttgat ttctgttatt taggaacctc
     6781 accaattctt ttacaagtga aaaataaata caatacagaa agcagttcga gttcagctat
     6841 aagagtagga acaacaatta gaaaatggaa tcgtttaaat aagtcgacaa aaatttctgg
     6901 tttggatagc cctatcccca attggaaagc attaatagaa atgactgaag ctagtaagga
     6961 actggcagct aagttaactg aaaatagtta tttagcttat attaatgaaa aatccacacg
     7021 agaattatgg acactcgatg actaacaata tccttattag tatctatcca cgatacatgg
     7081 aaaaaattat aaacaaacaa aaaaactttg aatttagaaa tttctatctt acctcagatc
     7141 cttataatat cttttggatt tacgaaacaa tccccaccaa agctttaaag tataaattga
     7201 ttgtaaaaaa tccaattact aaacttaaga aaaatcaaca ctacttttta ggagacgatg
     7261 agtttgaaca attagt
//
LOCUS       DAFKHN010000110         7179 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFKHN010000110 DAFKHN010000000
VERSION     DAFKHN010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.110"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..321)
                     /locus_tag="LY912_002577"
     CDS             complement(<1..321)
                     /locus_tag="LY912_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBM6956214.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYE"
     gene            complement(318..560)
                     /locus_tag="LY912_002578"
     CDS             complement(318..560)
                     /locus_tag="LY912_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBM6956215.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            complement(1106..1636)
                     /locus_tag="LY912_002579"
     CDS             complement(1106..1636)
                     /locus_tag="LY912_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBM6956216.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFAK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1818..2474)
                     /locus_tag="LY912_002580"
     CDS             complement(1818..2474)
                     /locus_tag="LY912_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBM6956217.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(2601..3074)
                     /gene="dfrF"
                     /locus_tag="LY912_002581"
     CDS             complement(2601..3074)
                     /gene="dfrF"
                     /locus_tag="LY912_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBM6956218.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(3493..3711)
                     /locus_tag="LY912_002582"
                     /pseudo
     CDS             complement(3493..3711)
                     /locus_tag="LY912_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3742..4956)
                     /locus_tag="LY912_002583"
     CDS             complement(3742..4956)
                     /locus_tag="LY912_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBM6956219.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(5297..5539)
                     /locus_tag="LY912_002584"
     CDS             complement(5297..5539)
                     /locus_tag="LY912_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBM6956220.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(5571..6128)
                     /locus_tag="LY912_002585"
     CDS             complement(5571..6128)
                     /locus_tag="LY912_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBM6956221.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(6141..6329)
                     /locus_tag="LY912_002586"
     CDS             complement(6141..6329)
                     /locus_tag="LY912_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBM6956222.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(6342..6908)
                     /gene="amaP"
                     /locus_tag="LY912_002587"
     CDS             complement(6342..6908)
                     /gene="amaP"
                     /locus_tag="LY912_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBM6956223.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         2151 a         1496 c         1041 g         2491 t
ORIGIN      
        1 ttcatatatt ttatccatag caccaatatg ctccacaacc aaatatttat aagacggtat
       61 ttctttatac agaaagccct ctggggtaat ggttctttgg ggaatagaac agaaataata
      121 aagttttcca tttcttcttt ccataaaagc atattttacc caatttcctg attgtgaaag
      181 atacgctttt ttcaaactac tgttaaactt tctccaaaac tgtgtactaa tctgaatatt
      241 ctttttttga taattagtca gttctacttc ctgcccaata actgcaaatg cgtttaattc
      301 ctttatagaa aaatttatca ttttaccttg tgagcagtga taacggtata actgtacgca
      361 tttaccgtta taatacaatt atcaatcgtt atataccagt tttttccttt tcttgtgatt
      421 tccgcattag aaaggctaat tttttctttg caccattcaa ttacattttc tacattcaaa
      481 gataagttct ttttaattct aataacgcca agttcagttg tgtgaagtct tcctaagttt
      541 tccagtaatt cattttccat attttgatac ctcatttttc agcaaattta tttgtatgtt
      601 ttatacccca attataacat tctcatatca gcactacaat aaaaataatt aagcaccaat
      661 aatcttattg aacatctcca accgtaaatc tttcacacca tcagtgataa acactgagct
      721 gacagcaatt acgacaacta ccataattgc ctgcacttaa atttctgcaa aagaaaacga
      781 caatcaattt cttatttttt gaaatcaact gtctttctca tatttactat tcaattttca
      841 tagtgatata ggtacaattt atatcactac tgtaaaaatg gggttttgcc ttataaatac
      901 agcgttttcc gcttgttagt gtatagtgtt tcttgttttt tgtgcccccc ttgttagata
      961 acgggggctt tgaacggctc gcaagctcgc cgaaccgccg aagcgaaccg cccccttgca
     1021 agcatggcgg aaaaatctta aggattttcc cgccaacgtg gtcggatcgc tccgtcggtt
     1081 taacagcttt tctgtttctc tctagttatc tacgcatata aatcaaatcg gttattccgt
     1141 tataagtctg tgttttacaa agccttaact ttatttccct gtctatgttg cccaaaagac
     1201 gaaccccatt tcctaacaga gtaggaataa cagaaatgta atatttatca atcatatttt
     1261 tgcttaccaa ctgctgaaca agatttgctc cgccacaaat ccaaatatcc tttcctgctt
     1321 cttgttttag ccgttccaat aataaaacag gattttcact tgtaaaatga atttgttggg
     1381 aagaattgca ctctttatgt gttaatacat aagttgtaaa tttattatat acccattctt
     1441 gcggagaaag ttcagtaaca acctgatgag aagtattcca ccccattaag acagtatcta
     1501 tatctttggc aaattctgta taagtgtcga tgttttcatt gtcatttcca tgaccattta
     1561 gccaagctac tccaccatta ccgtccgcaa tatatccgtc aaggctcatg gcaataaata
     1621 aaactacttt tctcattttt tctcttttat aaatacaaac aggaatttat ttctcttttt
     1681 tactcataag ggaacaactg attgctacaa ataaacccat taaaatccat ggaaatgctg
     1741 ctcttataaa atcactaacc atactttatt cctccttaaa ttccaatttc cttagttcta
     1801 caaactgaaa tttttgccta tgaatgtatc ttgttcttta tacgcaaaca ggcttctgtg
     1861 tgcataatcc aatgtcttga aaacggcatt tgaattagtc cacaaatatc tttattacac
     1921 caataatcaa tcagccaaat tgctttttca ttgtcgttta ctacattcaa cgattctaag
     1981 tatccttttc tttctttcgg tatttttctt ttcaattcat cataagataa ccgttcaagc
     2041 attttctcag tgctttccca tacttcgaaa atatataaat ataattcttc cagattaagc
     2101 tgttttgaaa agtctgcaat ctgctgtttc atgagttcat ttcctgttgt aatgataggt
     2161 gaattgatac gctcttgata attgcctgca aaaaatactt gttcatcttc atttatcact
     2221 gtatgcacaa ctatatcttc aatgcggaaa atatgccaaa tagaataagc aatcgtctta
     2281 ctatgataac catcagcgtt tatgaagggg attgagttaa aatcttctct gcataattct
     2341 tctttgaaag atactaaggt ttgtattaac tgacttcgta aagtaagtaa agtatcaata
     2401 cccctcttat aagtatcttt cttttttatt tgtgcctgca ttgttttatt aagttcagac
     2461 cattccttat tcatattcaa tcctctctca aattctgatt ttatcgcccc atacaaactg
     2521 gaatttgtct tacaacaatt tatatatgca taaaaagcaa tatatttatg aaaacaccct
     2581 aaatccaaaa tttactcaat tcattttttc cttacataaa atgttctcgt atatttcact
     2641 tcctcaccaa gtgtttcccc tatcaaaact tcaaaatcat tgatatcaaa ttctggaaag
     2701 aatgtatctc catcttcaat atttaaatct acttctgtga tatacatttt atctactatt
     2761 tgcaaagctt ccttaaatag tccatatcca ccagatatgt atacatctcg tcctttagcc
     2821 aataataatg catcttctaa tgatttaact gaaactaaat tatctccttg atactctgtt
     2881 gtggtggaaa caacaatatt cattctatta ggcaacggat gaccgatttc ttcataagac
     2941 tttcgcccca taataaccac attacccgtt gttaactctc taaattgctt ttgttctccc
     3001 tttattttcc atggtatatt accattcttg cctataacat tattctttga cctcgcaaca
     3061 atcaaaccta tcatctattt catcctccat aatatgatgt cgtacctgtg attccatcaa
     3121 gtgcaccaca tcttaacaaa ctcaaaatta tctcgaacta accagctcga caaattcctt
     3181 ttttgtcttc atctgcatta tatcatattg ttataagcat tgccatttct tttctgcttt
     3241 tgaaaagtta cttatcagcc tatgttttgt aaagggtgat attcagcatt tctcacgcaa
     3301 caagcccttg acaaaccata gactaataag ttttaaggta atcaagcaga aatgaaatag
     3361 tctgctgttt cacggcaaca aaaaagagat accaacacac ttatgtagta tctcttagtc
     3421 tagtagcaat attcttttgt ttgcaagcag gtaaacatgg gctgtttctt aatatctttt
     3481 tgtttgggaa acaccttttt cccatccttt caccgttgcc atctctgctg cgcacaatgc
     3541 cacagggata aaccatagca aaccgcctaa taacaagaaa aatactaagc tgaagcctga
     3601 ggtcgcgaat gtgggatatt catataatga aacgaccatt gagatggtca tagccaaaaa
     3661 gccaaagaac gttaattttt ttgcaggaat tttcgttttg ctttgttgca tgaatcttcc
     3721 tcttttctat ttgaatttgt ttcaattgag tttgttgcca aagaagaaaa agtccaatcc
     3781 ttcttcttgt tcttcttttg tagtagtgat cgttgtaaag tgcatcgccg attttaaaat
     3841 cactgttgtc agcacatagg catacacggc agtaatgatg acaccaatca cttgaatccc
     3901 taagaagtac cagctgcttg gattcgttag taaatggctg ttagatgcaa agatccctat
     3961 cagaatcgta cctgtgaatc cgcccatgcc atgaacaccc cacacatcaa gtgcatcatc
     4021 ccattgtttc tttttacgaa aatcaacagc agcatgacag acgatacccg caatgatccc
     4081 aatcagcatg gcactttttg cttctacata accggcacaa ggcgtaatgg ctgccaatcc
     4141 agcaacggat cctgttagta cgtcgacaaa atcaaagcca tttcctttta cttttgcaat
     4201 gatcagccaa gtaatcatcg caaatgcaag agcgatgaat gttgaaccaa atgcattgac
     4261 tgcttgttca tctgctcgaa gtgcaccacc ggaattaaaa ccgaaccagc caaaccaaag
     4321 cagtcctgta ccgatagcag ctgccataag actgctatgc tgacttcttt ctcctaaagg
     4381 aatctttctt tgaccaagtg tgaggataca tgctaaagag ccgaatccag ctgtcgtgtg
     4441 gatgactgct ccaccagcga aatctctaaa tcccatctga tccaaaaatc cgccacccca
     4501 tatccagtgg caaacaggga aataaatcag cagattccaa aaaataacaa gtataatata
     4561 gccttttaaa ttcaatctcc ctgcaaaagc tcctgtcatc aaaggaacgg taatcacgat
     4621 aaacatcagt tggtaaagaa agaacattaa aaatggaatc gttgcaccat gaaacatgtt
     4681 ggggaagctt gtaacatgtc tcatcaaaaa gaaatctgcc gggtttccaa taacaccgcc
     4741 gatatcccgt ccaaaggcca atccgaatcc accaaatacc cacataatcg ttgttatccc
     4801 aacggagaga aaagattgag acatgatcgt tagtatatta ttcttccgtg ctaatccgcc
     4861 gtaaaaaaaa gctagaccag gagtcatcag gcaaaccatt gctgtacata aaatcatgaa
     4921 tgctgtatct cctgtattga taggtaatgt attcattttt ttcgcctcct ttctacgatt
     4981 acgagtataa aagaaggtgt agttgttttt ttcttctgtt tttttgaatt aatacttgca
     5041 tttataaaag acagacaatt aataaaagct tgatgtgttg tgctcttttt cgtttttcac
     5101 acaaataaag acaaaaaata aacggtcttc tttttataga aaaccgttta ttttcgtctt
     5161 tttttatttt taaagatatt ttttcataag gaataaagaa tacttcatat aaaatatata
     5221 aaaaagaacc gcagcgagtg tcgctacggt tctcaaattt gttcttcatt tcaacataag
     5281 tttttcttca atttgcttat aatttacgtg caaagaatga aacgactaat actaaaatga
     5341 ttgcaccgat caatgatgga atgatagcca ttcctgcaat tgttggtccc caagttccta
     5401 gtaaagcttg tccaattgct gaacctacta aaccagcaat gatgtttgcg atgatcccca
     5461 ttgatgatcc tttattcgtg attgctcctg caattgctcc aatgataccg ccgacgatta
     5521 atgcccaaat aaatcccatt ttaaattcct cctaactgac ttcttacttc ttattgtaca
     5581 cgtggttcgt tattttcttt gactttttgt gcacctttgc ctacagcaga ttttgcttta
     5641 tctgtttggc gtgaagcaaa ttgtcctgtg gattttgctg cttctgttac tttgtcttgt
     5701 actgtttctt gatctttttg gtattcttct tgtgttttga tgtctgcaac attcacattc
     5761 acttcgataa catctaaatg tgtcatattg tttacttcag tactgatcaa ttctttgatt
     5821 tggttgtaaa tatcttcgat gtctttaccg tattctacga tcacatctag atccacagct
     5881 acttgtttct tacctacttc tgtattgata cctgctgtta cgttatctgt gttgactaat
     5941 ttttcagcca tatttgagaa aaatccgcca tctaatgtca atagaccatc tacatctttc
     6001 aatgcataac cgatgatttt ttggatgact ttgtcttcat aagtcaattc accattcatc
     6061 atgcggtttt ctcctttttc atttgccaaa actgatccat ttgttgtatt catgtttttg
     6121 ttttccatct ttgtttcctc ctatgattta aaaaattgat caactattcc tgactgtttc
     6181 aaataaaaac cgattcctgc gccaattgct gtcatgatta tgatcaacaa tgtcttgaaa
     6241 aatccaatcg ttaaccataa aacagctagc agtagtccaa gacccccaaa gataataggg
     6301 agcttgtatg ctgaaaatag ttctttcatt atttggccct cctattccac tcgagagtgc
     6361 ttgtagtctc ttgtatcttc ttgttcttca taaccgctgt atgtgactgc cactttgacc
     6421 gtttcttttg ttccgagtac tttagttact tcttcttcga tatcttgcat caatacacct
     6481 gttttcccta ctaatgaaga agttcgtttc aagtctccgt tgacatggat atggattcga
     6541 tttttcgttg aacgtatccg tactttaggt gaatgaatga actcttcttc gtgtaaatgg
     6601 gaacgtacca acccttcgat cgcttttttg tcgattgtta gtttgccatc ttcccgtttc
     6661 ataacgaaag ttcctcttga ctttggatag aaaagaacga ctagcaagat gataatagca
     6721 agaacggcaa atactacagc tgcccagaaa atatattgtt gcatgtagta attcgttaaa
     6781 gtaaagaagc gaaatcgttc caattgttca ggcataatat acggcgcatt gatcaacgca
     6841 atcgctagaa atactgaaag tagcagtaaa ctcatgataa caccgattat ttttaacccc
     6901 ttattcattt tccacctcct ataaacttat ttttaccctg taaataactc taccgacaat
     6961 cacagtatag atagcgaaca gttagcatag catcagtaaa taaagcgcta ccaaacattg
     7021 ctggatcata acggcgtttt attgccagtc tgatactgaa ataacaattg cttacttatt
     7081 ctctatttac ttttgattgc tggctatact taaaggatat tattcaagat taaaaattgc
     7141 aaagattatg ctcagttatt attacaagat tctatttat
//
LOCUS       DAFKHN010000111         6872 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFKHN010000111 DAFKHN010000000
VERSION     DAFKHN010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.111"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..1329)
                     /locus_tag="LY912_002588"
     CDS             complement(<1..1329)
                     /locus_tag="LY912_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBM6956224.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIKPVVLVNFNILKNISKFL"
     gene            complement(1470..2072)
                     /locus_tag="LY912_002589"
     CDS             complement(1470..2072)
                     /locus_tag="LY912_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBM6956225.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            2317..2523
                     /locus_tag="LY912_002590"
     CDS             2317..2523
                     /locus_tag="LY912_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956226.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            2835..3554
                     /locus_tag="LY912_002591"
     CDS             2835..3554
                     /locus_tag="LY912_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBM6956227.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(3635..4318)
                     /locus_tag="LY912_002592"
     CDS             complement(3635..4318)
                     /locus_tag="LY912_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBM6956228.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            4536..6722
                     /locus_tag="LY912_002593"
     CDS             4536..6722
                     /locus_tag="LY912_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBM6956229.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         2522 a         1157 c         1301 g         1892 t
ORIGIN      
        1 aaggaacttt gagatattct ttaggatatt aaaattaact agcaccacgg gttttatttg
       61 tatataaatc gtttgagaaa aacgctggtt ttcaattgat gtttcaagga aaagataagg
      121 attggtcttt gtcaattcat ccaagataaa caagccaagg ccttcgtttt ttggatttgt
      181 ttttgttgag aacccttttt gtttcaactg gtttaacggt aatgtatttg ttgttgtatt
      241 gatcacacga atcatcacgg aatgattctt cttgagtatg gtcaattcga tttttttctt
      301 ctttgcagca ctagctcctt caatcgcatt gtccaagata ataccaagca tacgtacaag
      361 gtttaccgta tgtttcgtat ccagttcgat tggctcagga aaatgaagct ggacgatcaa
      421 ccctttttcc tgtgccatca tgagttttaa tgacagtaaa ctacggatct caggaacttt
      481 catattatcc aacatactta gattggccgg aaaaaggttc atcatctggc gtgtaggtaa
      541 tatcgtttga tcataataag accgtaatcc ttctaagtcg ccttctgaaa tatagctgtg
      601 aagagaaaaa agcagatttt ggtaatcatg tttgaattct ctcaagtctt gatagttttt
      661 ttctagatct ttgatataat cctgttgcat cctgacttgt tgctctaata actgatcagc
      721 taatttctta ttagagattt tccaataata aaccaagatg atcaggccaa cacacagata
      781 tagaatgaaa aaactcgtat tcaaagctaa gacatcaggt gtttcaccag aaaaacgggt
      841 ataaaaaata atgatatagt atgtaaataa tatcaatgtc ccgatcgtac cgatcatacg
      901 gcggtccaca gtgtgaaacc aagtctctaa cgattttttt aaacaaaaag ctaataaagc
      961 agataaaaaa gcggataaga caatgtgaaa atactgcaat gaatctcctg gttcaataac
     1021 cgaagatttc aaaacaaaaa aatcgccgat gcttgttaag tgatctccta aaagcgacgt
     1081 caataaccca aaaggaagcg cgtaaaccaa ttgttgacgc gaagtcgaaa agaagaaaaa
     1141 agtaagcatc agcattccta tagcaattag agcagtaaaa atccctaaaa tcgaatagac
     1201 ccatccaatc aaaatacaag aaatcagaat gactcccgca aacagatatt tgtatcggat
     1261 gtgatggtca atcaataaga tacaaattgt gtaaatcaaa tattgcaacg ctatggacca
     1321 taaaaacata aagtacagct cccattgatt tttaccaaat tatagcacaa ttggcgtatt
     1381 atttttttaa tttttcaggg attttgaatt cagaactcat accaaagcag cagccagata
     1441 caaaaaagtc agataagtta gttaattgtt taatgattgt ttttttcatg aaagattcct
     1501 ccaaaattca tcaagtagtt tgtaatagga agcaacgtag ctatttctaa aacaatccca
     1561 agtagcaaat aggtagaaaa gtaagaagct gagaaaaata acgtaatgag agaaaaaatt
     1621 agaaacatgc tgatcgcctt ctttaataat gggggacgtt tctcgggttc aatgggattg
     1681 attgctgtac ctcttgatcc atagcgaagc agtaacaaaa agcagctgat taacaaaaag
     1741 accatcattg ggaaggagat agtcaattgc agatgtttca tcaccaaggg aacgccccat
     1801 aaataaagta gtgtccacag cagacaaacg aattcagagt cggaatgcaa tccataagca
     1861 tatctgcgga tgcagatata agaaagaaag gtgattcctg tttccgccca tgagcctgtc
     1921 accagagaaa agactagaac gaccgctagt tttccaagat tattcaataa aacttctaag
     1981 acaaatttta cttggacata caccatatct tcttccgatt tgtctccgct gaataaggct
     2041 tctaataatt tgttcacaac tttatctttc atctcatacg tacctccacc acaaatttta
     2101 tgctaaaaaa aataaaaaac gtcttttgtt tcataaaaag tggttttgac atcaaaaccg
     2161 tcatgatctc ctaaaaaaat cttcgttttc caagaacctt accaaaaaaa gtgacagttt
     2221 tgatacgaaa agtacttttt atgacaagtt tgtgcttttt cgagtgattt atgttaaaaa
     2281 attactgacc ttataaaagg tgatggaggg attcttatgg aaaatgaaca attgtttgaa
     2341 gtcggcgaaa catatgcatt taaatctgat ttatttgaat caccaataaa aggaaaaata
     2401 gaaaaaatct atgaaaatag tgtgatgata cgtgtcatga aatgcgcagt agaagacaat
     2461 gataccgctc ataatctgca ctggcagtta gttgtacgca aatcaagtac aatagaagaa
     2521 taaaaacaga taaaatgttg agagcataaa gaggttgtga gtctcccgtt tagctctgag
     2581 ttacaaggaa taatgttaaa aaacagcttt tcatgtttta tgaatattgc cttgtgaccg
     2641 aggtgttggc aggagaatac tgtttatttg aaaaaagggc tgcgacaaga cttttgtcac
     2701 agcctttatt ttcatgaata ggagttactt ttggctactt ttagagaagt agcttttaag
     2761 gagcagataa agtcaaggct tttatttcta taaatgaagt agtaaaatga agaacagatt
     2821 ttattacagg aaggatgccg ataattgtga tcattgttgc aggaacgatc ggtgcaggga
     2881 aaagcacact aactgaaatg cttgcccaag atttagaaac aaaacctttt tatgagaacg
     2941 tggaagataa tgaagtattg ccgctatttt attctaatcc agaaaagtat acttttttat
     3001 tacagatttt ctttttgaac aaacgctttt tggcaatcaa agatgctttc agccatgatg
     3061 acaacgtact agaccgctcc atctacgaag atagtatgct gtttcatttg aatgcagatt
     3121 tagggcgtgt ttctgaagta gaagtaaagc agtatgaagg tcttttagaa acgatgctga
     3181 aggagttaga agaaatttcg ccacaaaaga aaccagatct actggtttat attcgtgtat
     3241 cctttgaaac tatgttagcg agaatcaaaa aaagaggccg ggaatatgaa cagctagaac
     3301 aagatcctga actctattcc tactataaag aactcaatcg acgatacgaa gagtggtatg
     3361 aacagtttga tatatgtccc aaaatagtga tcgatgggga caaatatgat ttcgtagccg
     3421 atccggcatg tggagaacaa atcgtacaag aaatcaagat gcgggcaaag aaaatgacag
     3481 aagaggcaga tgcccagtcg atccgctaca ctacaaataa cccgaaagca aagggaatct
     3541 ttacaactaa ataatataaa aactaagcaa attgctcact cgcagatatt tctctgtgag
     3601 cagcatcttg cttagttttt ttgattcatt gagatcaaat agtgaaccga ttcgtatgat
     3661 aaaattgcca taaatgaaat gtctgagtga gggccatgat caaaaataaa atggaaacga
     3721 tcaaaatcga atgggcgcca aacagatgat gacagaaaac aaggacaata gctcctgcga
     3781 taaaggcaag aacgacactt agatagtgga aaaatcgatc aaaatctgct ttttctttag
     3841 aaatacaata atcatataag ttcgttgcta ccccttttaa atttccagtt gtaaataaat
     3901 tagtgtaggc acgcccgttg attttatcaa aagctaccca ctggatcgat gcagtaaaag
     3961 caatcaaaat cgttactaat gcgggatgct catggacggg tgtcaaacta acaaagaaaa
     4021 aaatcactgc ttcataatat agaacaaaca agcgccagaa atgtttttct ttttttctaa
     4081 aataatcaat tagatacttt gttagaagaa tccctaagaa aaagaaaagg gtagacaata
     4141 cttttttacc aacacttagc cattctccgt caaatgcttg gatgatcgat agaatgatat
     4201 tgccagtttg agcagaggca aaagcaccat attggatata agtataactg tccatggctc
     4261 ctccgataaa tgtcagcaaa agtcctattg tacgcccctc gtgaaaggaa gtctgcattt
     4321 ttttcatcac cttttatgaa tatttttgtc ttccttatct tagcataaac gattgaaaaa
     4381 aaggaaaaat tttcagaaaa ctaaaatcat atcgcttccc attttcattt ttagaaaggt
     4441 ctgttagtat aaagaaaaaa tagacaacga aactttaaat aaccaacttg aaataaacaa
     4501 attcaaagaa gaaagatggg aaggaaatca atcagttgaa tgaaaaagaa attctccgat
     4561 tacaaaaaga attgaaacgc tgggagaaca agtataaaaa gcttcaacaa gtctttcggc
     4621 tacaagaaga aatcattgct acctatgaag cggcttatgg cgaagcaccc ggacttattg
     4681 aggaagaagt acaagtaaaa gaaagtgaag gaaacagctc tttctttaaa atgatggaga
     4741 aacgttccta taatcgcttc aatcaagaac aaaaagcagc tatcacatat gatatgaaga
     4801 aacatcttcg aatcatagca ggagctggga gcggcaaaac gcaaacaatc tgtgcaaaag
     4861 ctgtttatct gatgacgcaa aaacaagtag acgaagaacg catactaatg atcactttta
     4921 caaggaacgc tgcaaatgaa ctaaaaaaac gagtagataa tttcagccag agaaaaaccg
     4981 ctgtccatat cggaacattc catagtatct tttttaggat atacaatgaa atttgtcgaa
     5041 aatttcctga agtagcaatg caaggaatac aaggagactt ttcaaaggat actgcacaaa
     5101 aagtgaatgc tgttttgcaa cagctgatac gtaaatataa tctttatata tttgatcaat
     5161 atggagaaaa aacgattgct tctcggttag actattggca gaatatgaac ctttcagtag
     5221 aagaaatggt tcagttagtt aaagaaaaat atgattccat tgataagaat gcacgacagc
     5281 cgatatcaga acgactgtat ggattgctca cggaactcca agaacaaaaa agaagccagc
     5341 aattgctaga gttcaatgat gtactccaaa atctgaaaag cgctttggag aatgaggaga
     5401 tccagcatta tatcggccaa aaatatgatt atctattcat tgatgaattt caagatacta
     5461 atccacttca atgggaaatc gtgaaacgga tgacaaagga aaacaggatc aagttgattg
     5521 ttgttggaga tgatgatcag agtatctatg gattcagagg atcagagcca gcatacatca
     5581 agaactttga aaaagaatat cctaccaaaa ctcttttctt attaactaat tatcgttctc
     5641 gggcagctat tgtccaagga gcaaatagat tgatcagcta taataaaaat gatcggatac
     5701 caaaggcgat gattccagca caaaaagaag caggtgttat ggaagcctat ttgttttctg
     5761 atactaaagc agaaagtcag tggctaatca aacaaattca gacatttatt caaaaaaatg
     5821 ggaaatataa ggaatcaatc atattatacc gatcagcttc acaaacgcag cagcttgtcc
     5881 aatctctgct gaaaacgaat attccttttg tactggaagc agatagtcca tatgaaggta
     5941 tctttggtat caagtctttc caacatttct atcaaaaaat tgttcattgg caaacagcac
     6001 tgaatctgca aaagaaaaat caggcctacc agcaattgct ccggcagctg atggcagact
     6061 gctacctgaa aaaaagtgaa tgcgatcaat acttttctcc taaatatcaa aatatagccg
     6121 ttgcagatta tattttgtcg ataagcccca atttaaaatc gaaatctgca gaaatccgag
     6181 agtttgagga agcgttgcgt aaaacagacc agcatcaaga aatctattcg cttgttcaaa
     6241 gctatcttca tctgccacgt atagctaagg aaatcgacca gagtgatcaa gaatggatac
     6301 gagaagaagt aaagcagcat gctactttca gaagactcca agccttatcg caagaaaccc
     6361 aagcgacagc taaagaatta aaaacccgct tgattgctta cagacaagga aaacttgatg
     6421 cactatgtat ccagagcatt cacaaaagta aaggtcttag ttaccgaaat gtctttttga
     6481 ttggttgtaa cgaaggaagt ttgccttata acggagcgac agaaaagaaa gtaatcgact
     6541 ttaatgaaat aaaagcagaa ccagtaacga cgatagaaga agaacgaaga ctattttatg
     6601 ttgcgatgac tagagcaaga aatcgtctgt atctatgtgt acctcaaatg aaaaattcaa
     6661 gaaaattgaa agtatcgaga tttatcaaag aaaccgggag tcgtgtgaaa aaaggaaagt
     6721 gatagaagag agggtgtgac agaagtggtc agtttcaaga aagaagaagg aatgtacgaa
     6781 aattgcttct caaatttttg tgaaatttca gcttattttc gaagaagcta tttctggaac
     6841 acagtttatt cggaaaaggg aggtgtgaca ag
//
LOCUS       DAFKHN010000112         6731 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFKHN010000112 DAFKHN010000000
VERSION     DAFKHN010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.112"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            247..2922
                     /locus_tag="LY912_002594"
     CDS             247..2922
                     /locus_tag="LY912_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBM6956230.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            3104..3343
                     /locus_tag="LY912_002595"
     CDS             3104..3343
                     /locus_tag="LY912_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956231.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3359..4732
                     /locus_tag="LY912_002596"
     CDS             3359..4732
                     /locus_tag="LY912_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956232.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4736..6370
                     /locus_tag="LY912_002597"
     CDS             4736..6370
                     /locus_tag="LY912_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956233.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6533..>6731
                     /locus_tag="LY912_002598"
     CDS             6533..>6731
                     /locus_tag="LY912_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956234.1"
                     /translation="MKKMGKCILCEKYTQLTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2373 a         1079 c         1344 g         1935 t
ORIGIN      
        1 atggacagaa acatactatg agaaaatata taaagaaata attgaacaat attttcctaa
       61 ataatttaat aaggattgat ttatcgtaaa agaaaaaagt tgtgatttcc aaaatcacaa
      121 cttttttctt ttgtcaagat tttgagtggg atatattttt gtagaactga agatcatgaa
      181 attatgagag gttggaggta atgtagtcat acaaataaaa attttttaga aagtgagtgg
      241 taattaatga aaatgaatca cacttcaatt cagaagcatt tacaactgtt aaatacactg
      301 gggatttctt atgttaattt gagaactttt tctacattaa acaagaaaac cgtttctcat
      361 attttttcta ctgcagattc tcaagcaatt attaactatt tagaaaaaca gaaattgtct
      421 gaaggtacag taaacataac ttataatcct attaaacaag aggtgattac acaaaaaaag
      481 cattctgtga gagacaatga tattgaaaaa attcggtttg tatttattga tattgaccct
      541 aaaaggaaag agggaagtgc aacagatagc gaaaagaaaa aggcagaaaa tgttatggaa
      601 caagtagaac gttatttgaa agaaaagaga atagaatcat ttgtaaaagt tgatagtggg
      661 aatggctacc atatttttct tcccataaat gaacaaccaa ataatcacga gacgattctt
      721 actattcaga attttcttca attacttcac cgaagatttg gagtagaaga tgaagttgat
      781 attgatactt ctgtttataa tccttcaaga ttatgcaaat tagttggtac accagcggtc
      841 aaaggaaagt ccacaaaaga gcgtccgcat cgtttatcta gtttcctttc tattcccgat
      901 aacatagata gaagtaattg ttttaaaatt cttgaacaga tagttgaaga aaattccatg
      961 atgtcaacct ctagagtaaa aagccatcca tcttttagag aagtgttacc ttttattcaa
     1021 gcagactata aacaatggtt agctcactat cctgaattaa cttataccat aaaagagggc
     1081 gatcataaag gagttacctt acttatattt gacgaatgtc cattaagaaa acacacgaat
     1141 aattctaatg gttcttgttt gtctgttacg gctgataata agattcgatt tcattgtctg
     1201 catgcttcgg ataaaaataa agatattcaa gactttgtaa aaaaatatcc gttgccaaaa
     1261 cctgtaaatc cttctgtaga atcattagaa tccaatcaag aatattattt tgaccagttt
     1321 aaactgaatc aagaaggagt atttttggtg aaagaaggtc aagaagaaaa agttgcttgt
     1381 ccgatgttta ttaagcaaat acgcaaaaat atcgaacaaa aagtcattac acttgttctt
     1441 gcctattatg tcgatcattg ttgggatgaa atagaaatag aaggtggatg tttacaaact
     1501 aataatttta aacaattagc aaaacatggc ttaatcatta aagctagaag agaagctgaa
     1561 gtcgttgact ttttacagat tcaacgggag aatgctccaa tcttttttga acatgaatct
     1621 cttggctgga aaaaagaaaa tgaagcaatg atttttcagt tacaagattc ttttggacgt
     1681 gaaattcctt ctgtattaac taaaaactca tgctaccaat taacaactaa tggtacagaa
     1741 gcggaatttg acgcattggt tcataagtat gttttaggaa cgaacttaga acttgcttgg
     1801 tcgattggta ttgcttctat tgtgttaggc tatttaaacg ttacgaaggc taatactttt
     1861 ttgagtttac taattaacct acagggcaag agcacaacgg gtaaaaccac tacgttacac
     1921 tttattgcct ctttatttgg aaatccaact acggttctta gaaatatgaa tgctaccaat
     1981 aaagccatta taaagctagc atcaaacaat cagggaggtg ttccactaat actagatgag
     2041 ttaggagcag caactcaaaa taactttagc tcgttgatct atcaattagc ttcaggagaa
     2101 gaaaggctaa gattagattc taattgtcag cttatgccac aagagacttt ttctgttttg
     2161 acccttacct cttctgaaga gcgtttggaa aattatttca atgagaaatt aactggtttg
     2221 aaagttcgat atatcgaatt ttctgatatc aagtttacaa aggatgcgaa tcacgcagag
     2281 aaagttaaaa gtctttcttc taatactttt ggttggggta taaagttatt tcttttgaaa
     2341 ctctttgaac aagggattac aaaaattgaa gcaacttttg tcgaagctca aaaaaaacta
     2401 tgggctgttt tacctgaaca ttctttgaag caacgcattg gtaataatct agctttgatt
     2461 tatagtggag ccctcctaat tcaagatata ctgggctatc ctttacgatt agagcatata
     2521 cagacggtgc ttattaattc gtacgaacag ttaattgtag atactagttt aggaagtgag
     2581 caaacggtat ttgaccgagt gaaaacattg ttggtgatga atagccataa atttttaaca
     2641 aacagtgaca acaaacatac gcccagtacg atttggggaa aagtatcaat tcaaaaaaat
     2701 ggggatatta aggtaaatat ttttcctatc ccgtttgagg acttgttaag gcgagaattt
     2761 caagtaaagg atctaaccta tctttttagg caattgcttg attcgggtaa tatgtgtgca
     2821 gaaaaaggga gaagaacgaa acgtattcac atgaatcgtc aagttcttcc aacatacgag
     2881 attctattac cttcttcact caaatcgtat tttcgattgt aatttagaat aaaccaaagt
     2941 atgaaagtga ggcaccatgt tatggaaata tttcttattg atttagcaaa acaactgatt
     3001 acttatctgt atgatagcga gcaaacccaa acggaagtaa atgaagcttg atctatgctt
     3061 catttacttc attcaatcaa acatgaaaga aaggaaaatt ctaatgacta aaaataaaat
     3121 gacactaaaa gcagaggttc ttctgtatat tcaagaacat ttttcaaatc aagccttttt
     3181 tacaaaacca atttacttgg atttcgaaat aagaggggta tctgctggat ctatcggggg
     3241 tactcttcaa gcgttgaaga acgaaggata tttagaaaat cactttgtgc aacgttcgtt
     3301 caatagaaga gtcgtgaaaa aatggtattt agttcattca tagagagggg aatcaagcat
     3361 gcgtgtggct tgttatgatc gaacgtctgt ttatgaagaa gcgaaaatta gtaatgacgc
     3421 tcaatatgat gcagtgaaag agtatgtttt agagaaatat gaacaaattc cccaacgatt
     3481 ttcagacaaa ggagaatcag gggaaaaagc ggagcgtcca gcttttcgac agcttagagc
     3541 ttgggtttgt gcgtcagaag aagagggggt gatctatgtt tggcgttatg atcgattggc
     3601 acgtcaagcc aaaatagcct tagaatttat tgagttgtgc caacaacatc aggttcaagt
     3661 gtattcgatt tctgaacctc ttcctgcttc tttctcacac gcgtcaacga ataaactatt
     3721 tgtgcaatta ttgttcactt ttgcagaaca acaacgaaac gtcattattg agaatgttcg
     3781 tgccggactt tcctataaaa agcaacaacg gcaatatttg tcttctgcgg taccatatgg
     3841 gtatcgttta gtgaatggga aaatccaaca agaagtacac gaagcaagga ttgttcgcta
     3901 tatttttcaa ctttatttga ccaaaaaata tggctacaaa aagctttgtc aacgattgac
     3961 gcaacaaaag cttttcttcc gcgaacgtcc ttttcagccc tatcatattt atagtatcct
     4021 aaaaaatcca ttgtactatg gcgaaatcaa aggaggatct ttggggaagt atctaggaac
     4081 ctttgaaccg attctctcga aagcaacctt tttacaagcc caagagattc gccaatcaag
     4141 gtgtacagct aaaaaagata cgtatctgta cttattacgt caaaaaattc ggtgtccctt
     4201 ctgtggtcgt catctgagtt cgaagtatca atggaataca aagaagacga agacgcttca
     4261 ttattatcat tgtaccgacc gaagctgcca aggaattttt cttcgggcag aaagggttga
     4321 gtcagaagta ttggaaaaga tacaggcttt ttttcaatac gaaggcgtct atcaagcctt
     4381 gattgcccaa ttaacgcaac aattagccga aaagcgaaaa gatgaaaaac gcaaagtaat
     4441 ccaacaaaag aaacaagaag cacaatggat taaggcattt gaagagggca attgttcact
     4501 ggaagaactc aagcaacaac tgcaagctct tcaaaagccg atgtctactt cttcgtttct
     4561 ttcactccaa cagtgtgaag caaaagtgaa agaatggctt caactaaaag acctctctag
     4621 tcgacaatta ttatgtgact atgtttgtcg gattgaggta acaaaggata aaacagtttg
     4681 tgggatttac ttccgacaac tgacacaaaa tattttagaa aggaacgaat gatctatgga
     4741 aatgatacaa accaaacgag tcgcattgta tattcgcgtg agtacacaag aacaagcttt
     4801 agaaggacat agtattcaag cacaagaaca aaatggacga cagtttgccg aacggatggg
     4861 ctatgaagtg gtagaagttt atgccgatga aggaatcagt gggaaatcca caaaaaatcg
     4921 gttcgcctat caacgaatga tgaacgatgc tcggaaccat cgttttgatc tactagtgat
     4981 ttggaaattg acccgtctcg gacgcaatat gttagatgtc ttacaaacag tcgaggaatt
     5041 attgcgatat gacgtaggat tacattcgat ctcggaacaa tttgacgtga ccacttcgac
     5101 aggtaaattg atgttacaac tccttgggag tttcggtgaa tttgaacgca accaaattgc
     5161 ggagaatgtt caaatgtcaa tgcaaagctt agtgaaagat aaaaagcgtt atgcaggagg
     5221 ccgacgttta ggctatgtca gtggtattga cacgaatggt caaaaacaat tggtcattga
     5281 accagaagag gcgaaaattg ttcgtctgat ctatgcaaaa tatttaggcg gagcagggta
     5341 tcgagcgatt gccaattttt tgaatcgtca aggatatcaa acagtcaaaa agaatgcttt
     5401 ttctaccacg gcagtcaaag atatcttacg caataaaatt tatgcagggt atttagaata
     5461 tgcgcgctac atcaattggg aaaccaaacg acggaagggg aagaatccga gaccgatttt
     5521 agtgaaagga acccatgaac cgattatttc ggaagaagat tatcaaaaag tacaagaacg
     5581 ccttgcttta gaaggaaaac aacccaaatg gaaccataca ggtgaaaatg tattgacagg
     5641 cttgttacgt tgtccagaat gtggcgcacc gatggcagcg agtaatgtca caaataccct
     5701 aaaggatggc acaaagaaac ggattcgata ttattcttgt tcagtctttc ggaataaagg
     5761 agcaagtgtg tgtcatgcca attcgattcg tgccgaacaa gcggaaacat ttgtcgccga
     5821 ccgattaaag gagatcgttc agctaccaga agttcttccc cgattggtgg cagcgttaaa
     5881 tgaagaaata gtgcgacaaa gccaaccatt ggaacaagaa ctcgtggtgt tactggaacg
     5941 aaaggaagaa ttgaagacta aaattgaaaa atgggaagct gctttggaag atagtcctga
     6001 attgtttccg atgttaaaag accgcttaga cgaattgact gaaaaacgac gacagttgca
     6061 cattcgagaa aatgaaatct tagggatctt tcaacaagga gagccgattc aagtcaaaga
     6121 tgtccaacgg atattgacta gtttggatcg ttttcttgcc cagagtgaga agaagcaaat
     6181 caaagccttg tatcgtacct ttatagagaa aataaccttt gatcctaacc ataaggagat
     6241 gttggaaatt acgatgaaat tcacgcatgc cgtggtacaa caattgaatg agcaatatca
     6301 aatagccgta tccaaaacaa aggatacggc tatttttgtg ttaaaaacac cctttacgtt
     6361 aacgatctag tctaggttat atcaaacaac gttagagggg cgctaacgct tctctagcga
     6421 tttgaaatcg ttagagaagt agttagggag gtccttatca taaataggga tatttattaa
     6481 tgaatatttg aaatataatt gtatataaga attaaaaaga gtggggatag atatgaaaaa
     6541 gatgggtaag tgtattttat gtgaaaaata cactcaactt actaaagaac atgtaccacc
     6601 taaaaaatca gggaatactg gaggtaaaaa gaccagaact ggtaatttag atgatttcct
     6661 taagagcgat tttacaaaag gtgattttcc gaaggggatt aaaaggaaac ctcaaggaaa
     6721 tgtttattat a
//
LOCUS       DAFKHN010000113         6643 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFKHN010000113 DAFKHN010000000
VERSION     DAFKHN010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.113"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(1..859)
                     /locus_tag="LY912_002599"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LY912_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LY912_002600"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LY912_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBM6956235.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LY912_002601"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LY912_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="LY912_002602"
     CDS             complement(2603..3421)
                     /locus_tag="LY912_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBM6956236.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LY912_002603"
     CDS             3582..4271
                     /locus_tag="LY912_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBM6956237.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LY912_002604"
     CDS             4285..5787
                     /locus_tag="LY912_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBM6956238.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LY912_002605"
     CDS             5800..6276
                     /locus_tag="LY912_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBM6956239.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="LY912_002606"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="LY912_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DAFKHN010000114         6617 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFKHN010000114 DAFKHN010000000
VERSION     DAFKHN010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.114"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(30..572)
                     /locus_tag="LY912_002607"
     CDS             complement(30..572)
                     /locus_tag="LY912_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956240.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(593..1684)
                     /locus_tag="LY912_002608"
     CDS             complement(593..1684)
                     /locus_tag="LY912_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBM6956241.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(1692..3902)
                     /locus_tag="LY912_002609"
     CDS             complement(1692..3902)
                     /locus_tag="LY912_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956242.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(3918..6446)
                     /locus_tag="LY912_002610"
     CDS             complement(3918..6446)
                     /locus_tag="LY912_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBM6956243.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
BASE COUNT         1987 a         1463 c         1005 g         2162 t
ORIGIN      
        1 ataataaata tgagtgttca ttttttattt taatacgcac tccgtacata ataaatcttg
       61 atcgcatcaa tcttttgagc ttcttgatct actttcaatt gaagtaatac aaattgagta
      121 accttattca ttgtttcttc tccaaataac aaatattgat ccggattctc tatatcttgt
      181 gtcacctggt aaagtttccc agttgttttc atttgtacat gcgggtctac atcaatacta
      241 ttgtctttaa tacaacgatc tgtcatatag tccctcacag cttgattgcg tttataaaca
      301 tctgtgaaat tactccattt tctagcaaaa tcttttaaga aattttttgt catttcatct
      361 atttgcattt gttgcgctgt ctcgtcttct aatgaaccaa tttgactgtt actttcagta
      421 ctttgaagag ttccacttgt ttcttttact gcttcgattg tttcttctgt cgttctcaat
      481 tgtgtttttt gtttttcaga agaaaaccaa tgacaaccag taagacctat caaacataac
      541 caactaaata ctaaaattat cccttttttc acgtttctag tcactgcctt tcttatttca
      601 ccttacgaac cagactacga atttttgttt gattgtacgt gcgttgatac cgagccataa
      661 tccgtccttg ctcggcattc tgttccacac tagagaaatg ttgtccgcca tatgaaacat
      721 ctgttataat tccggtgtga ccatagattc caggagacaa tgcaccacct gcttgccaat
      781 tcaccacatc tcctgcttgt aaatcacttg gttttgggtt catgattact tgccaaccat
      841 aggttgtcca gttataatct tcccctatta acatcgcaaa catgtgtcca gaacccatta
      901 actgtgggcc acctaattga gatacatacc atgccgtacc accataacat tccccattat
      961 ttacggatcg tccaatgatc cgatccaaaa ccttcgcatt gcctttactt tttcctgcaa
     1021 taagcgaagt tttttttgtt ggtaggctat tccaatgctt gatcgcaaaa gtatcatatt
     1081 ccgttaagtt ataggacgtt atgatactca ttgctcctcg ataatacgga ctcccttcgg
     1141 taatacctgc tgccgcatag cctccacgac ctagaatcaa taaacaactt ccaggatctt
     1201 tattgcccac acattgatta aagttgcttt ggctcgccac cataaagcca taatagtcat
     1261 aacaagcttt taagttcgga aacttcatat agaaaccacc ttcagaacca ccaattccac
     1321 gtgcagaacc ttgtgggtag ggacaaccag gaaaccaggt aatcccaaaa aagttcgtat
     1381 cgtttcttcc agattgtgac tgtccataag ctgattcata gcctaattga gaaagaatca
     1441 cactcggtaa taactgatac tttacagctg caccaactgc tgcttgcgca tgttcatctg
     1501 tgattggacc acgtccttta atctctgaaa aaatcggtaa tccttcggta tattccccat
     1561 taaaagcgac agctagacct gtagcttctc ctccatgctc agaaagttct cctgaaaaaa
     1621 agaatggcaa tagaaaaaag ggaagaataa agaaaagaag acaacctaga caccctttct
     1681 tcatttcttc ctcatccttt cttcgataat ggtttttgga ctgttcgtcc ttttggtaaa
     1741 gtaaaatcag ttcctggttt tgcgtccaaa atcggcagtg ttttaggatc cttttctatt
     1801 ttttccgatt gctctgttgg cttatctaaa gaagaaaatg caggttgtaa cgattttggt
     1861 gcggaaatcg acggtttact ttcagacgaa cgttgccccg gttgttgcac agaacgattt
     1921 cctgatagag tggctaccga cgaattagga acagagtatt ggttcaataa ctgctgcatt
     1981 gctggataac tcccattttt cgcctgattt ttcacttggc gaatctgttg tgaaagagaa
     2041 ccagcagctg ttaattgtgg cacgggtact tttccagaag gcaacggaat cgattgacca
     2101 acaaaagcga tacctttatt taacaatggt tttctttgat tattcccttg ttgcttactc
     2161 aattgtgcca atgattgtac ctgttgtttt ggtcttactg aattcatgga cgaatttgga
     2221 atcaaaccat ttgaaagacc agaattccac tctgttttcg atttggtaga agacatttca
     2281 ggctctaccc catgataacg aacatgacga ccactataag gcaaggcttg atttgaacgc
     2341 ccacctagtt caaagggatt aaccacttgc ctccctttta ccgattcttg tggtgtacgt
     2401 ttttgttgaa acttttgaaa tccatgtatc gctgcagaag cgagtggatt cgttgctcga
     2461 tacacattcc ctgctaatcc tgcacctttg attgccaaat tttgtccagc agttgatagt
     2521 tgaccaggca gttgtttcat ttgagacaaa gaatgacttg ctatgttttt cgtgttgttt
     2581 atagtttgat ctgcagctcc taaccctagt ttctttaata aatctttccg ttttacaatg
     2641 agtaaaattg ataggagtgc tttgacaaac atatttccta aaaaaccaaa aacagtattc
     2701 attggaatta aatcgtctac tatgttatag atcaaaaatg ccaccaaaat aatcacactg
     2761 taaaaagatt tttgaaacat caagcccaaa aaggacttta aggtattcat gagcatataa
     2821 tcaaatactg gaacaaaaga agcgagtaat gaaaaaggaa tcacaagtaa taaacacaac
     2881 accaacattt gaaagataaa acgaatcatg ccaatcacta caagtggtaa tccaatactt
     2941 agattaagca atggcaccat agaaccaacg actgctttat aaacagcttt agttggttga
     3001 atatagacac gataagcctt ctttttccct ctatcttctc ctgcagcagt ggtcactttt
     3061 gtctcaatat cagataattc ttcacttgac gcttccttgg ctagaaattc ttgtggttca
     3121 atctctgctt gatacaattc ttctaaattt gttgtcccat aatttaacaa tatatacgga
     3181 tcaacaacag ccgctttata ataaagttgg cgcacttttt gaatggcttc cttttgtgtc
     3241 gttggcacta aaacaccatt gacatctttt gtcgccaatt catctagact atttgtagca
     3301 gaaaaaataa agccttctac ctccacggac aaatcattta accctttggt aaaagcttct
     3361 cctttactag gtacgttact accatagcca aaccaaacca ttgaaaaaat gacaacgaag
     3421 agaaatcgaa taaacaccat ttttgcgtaa tgtttccctc taaatatacg aagagtaaat
     3481 agatataaca catacaagac gacaatcccc gcaccaatag gatcgtatat ttttgaataa
     3541 atagtatccg aaaaagtgaa aaactggtga attaactcgt tcattgcagc tccttcatag
     3601 agcttctcaa tgacaaaatc aaggccttgc caaatcaatt tacttaaact aaagaacata
     3661 ttcgtcatca tttttagaaa atctgtgcca tttgccccaa ataacatttt gcctaatgaa
     3721 aattcactat cagataaata agaagaaaag gtatcaatat gaaatttccc aatctcatag
     3781 atcgattgat ccacctgctt ttctgccgca tacaccaatc caccaacaaa aagcagtccg
     3841 aatccaatcg ttaaaaaaaa caaaacgcac catttctttt ccttatgctt tatataagcc
     3901 attgtttcac ctcatttcta ttgcatgatt aacgtatcct gttcttctac ttgagagtga
     3961 cttgtttttt ccgttgtttg taatgcagcg gtcatttctt caaacaaact gtgtacattg
     4021 agttttccta cacgtccata gggatctaac atccaacact gtcctttaat catgtggctc
     4081 atttcagcta agttcgcttc atttacttcc aaacgtaaat gattcaaaat cttttctcgc
     4141 tcactgtctt catcaaaagc aaagacgaca ccaaaattcc ctttttcttt atctgaacct
     4201 aagtcaccaa taaattgtgt atctaacact aattgattca tctgggaacg ccccacacgt
     4261 gccattgctg caataatact acgtcctgcg ttcgaattat taaataccca tgcttctgta
     4321 aaataaatcg ctgttttctt actactatct cgttttccaa acatttcaca aaaacgacct
     4381 aaactaatca tcaaacacaa agactttcga tccgcatctg tatatagttc tggtcggaca
     4441 ttgtcatttg gtaatttcaa atcttggatc tctaaaatcg ttgttttggc attaaagtct
     4501 aatcccgggt tttctccata agaaaatcct aaacgtaaaa tcgaatcttc taccgtcaag
     4561 cgtaaaaact caccatattc tcgaacctct ttttgttcca tttgttctaa atagtcgacc
     4621 acatgcatca agccaacttg ttgtccggct tctttttgaa ctaaaacttc ttggattccc
     4681 tttaataccg ccccttttaa aaggtgattg gtacctaacg gacttaactc atcaatcata
     4741 tcctgggcta cttgtttcgc atctactcgg gataaacaaa caattggatc taatacacca
     4801 taattacggg gatttgtagc atctaacgtg acataactca ttttttgcaa atgttctaca
     4861 aacaaagggt aatgtttctg ataatacggg tcttgaatga gtttcgtaaa ccatttgcgc
     4921 ttttctcctt tgggatccac aaataaactt tgtacattca taaacgaact atacaaaaag
     4981 agcaagccaa ctaaaaaggt cttcccttta ccggtttttc cagttactgc tacatgaggc
     5041 gcatcaaaca acgcaccttt gattccttcc gcaatggcta gaagattcaa aaagacaaaa
     5101 cgatttgacg cataaattaa ttcttctaat ggtgtttttt ctcctcgaga accaccatcc
     5161 cctaatgtat cttgccgacc aatataccag ccggattcca tacctaattc tgatactgct
     5221 gaaaacaacc attcgccaac tgcttctaca gttgttcggt gcttccaatg taactgccgt
     5281 cccaatggtt gccctaataa acatttatag aacaattctc gttgatcatt ttttgcacgg
     5341 tggatatgga taatcgtatg aagttgttga ataaccgttg cactattttg acgaacttct
     5401 tcaaccgttt gaccgtatac aataaaacat gcgatccaat cgacgacagg ttgcccatta
     5461 tctactcgtt gctttaaatg ttttactaat cctcgaacag ttaataagcg ttcactaggt
     5521 tcttcatcat tttgaaccaa ttccttatgc tctgttttga accgttccga tagccaattc
     5581 agttttaaac caatacctcc ctgtcctttc aagcgtggat agtgaatttt cattcgcaat
     5641 tctgctggga aagaaagatc ctgagcaaat tgaaatagat cacaatttct catattttca
     5701 ggtgtttccc caataggcaa caatgctaaa taactactcc ctaactcatc ttctaattga
     5761 agaaggcctt tatgttcctt cggtatacgt acatacgttc cttgattgtc tttcagtact
     5821 tcccaattat tttgttcttc tactttgtga gccattcctc gaatatattg cagacgattg
     5881 agatacaaca gctctttttt tactaaggga cgaatagaaa agctataaag taattgtgtc
     5941 acttctttta cataaggatc actttcagaa aacaaagttt ccaaatcatc tacttctaat
     6001 ccaaataagc gtgctaaact tcctgctaaa tctaaccaga ttagatttat tacatcatga
     6061 aaactctcca ccgttgcttt ttctttgact ttgattccta aaataaatga aggacgatag
     6121 acttgacctt ctcgttccaa caatgtcact gtttcttttg cataatacgc accaattgct
     6181 tgactatcgg gagaaaatcc ctttcctaat gtgtcaaact tcgtccgtaa attcattgtt
     6241 cgtggataca tcaccaactc cacatcttca taatctgcta aaagcaacag taaacgagcc
     6301 atcatttctt ttatttcctg tgtctttttt ggtgtgtttt ttgaaattgt tcgtggaaaa
     6361 acatgatagt aggcccagat acaatcctct ccatttaaca aacaattttt cttgaatgct
     6421 tttactggtt cttttacaag caccaatgaa tttcacctcc caataaaaaa ggaacaacca
     6481 gttgattgtc cctttttcta atcctctaaa taaacatact tattcacaaa aagtaattct
     6541 tccaatgcat tgtttgatac cttgtcccag ttataataca cacaatcacc attcatcata
     6601 cgaatcatat aacaaaa
//
LOCUS       DAFKHN010000115         6607 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFKHN010000115 DAFKHN010000000
VERSION     DAFKHN010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.115"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(48..698)
                     /locus_tag="LY912_002611"
     CDS             complement(48..698)
                     /locus_tag="LY912_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956244.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(798..1307)
                     /locus_tag="LY912_002612"
     CDS             complement(798..1307)
                     /locus_tag="LY912_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBM6956245.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(1508..2377)
                     /locus_tag="LY912_002613"
     CDS             complement(1508..2377)
                     /locus_tag="LY912_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBM6956246.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(2397..3518)
                     /locus_tag="LY912_002614"
     CDS             complement(2397..3518)
                     /locus_tag="LY912_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBM6956247.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(3520..3915)
                     /locus_tag="LY912_002615"
     CDS             complement(3520..3915)
                     /locus_tag="LY912_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBM6956248.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(3934..4740)
                     /locus_tag="LY912_002616"
     CDS             complement(3934..4740)
                     /locus_tag="LY912_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBM6956249.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(4733..5521)
                     /locus_tag="LY912_002617"
     CDS             complement(4733..5521)
                     /locus_tag="LY912_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6956250.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(5535..6011)
                     /locus_tag="LY912_002618"
     CDS             complement(5535..6011)
                     /locus_tag="LY912_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6956251.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(6083..>6607)
                     /locus_tag="LY912_002619"
     CDS             complement(6083..>6607)
                     /locus_tag="LY912_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBM6956252.1"
                     /translation="ELRKENNILFIVGTLNPHLEDVEFFSIEDMILGMNISKFSNQLN
                     RHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDAIYILQNDLGISFDNN
                     TCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFKQSFSVVEHYYSVDIP
                     IHEVKYVYDYVKRA"
BASE COUNT         2052 a         1409 c          927 g         2219 t
ORIGIN      
        1 cttccatttt tacagttata actagtatta tcatgaaaaa tagcctttta ttgtctatgg
       61 gaataataat ttaaaattgg tactttttta ttaattagtt catcgcccaa taatctctcc
      121 agtttcttag catctcctga ctcaaccgga attatccaag cccagtctaa ataatttttt
      181 aaaatctcat catattttgc aaatatttca ttgccatatt ccgtccttaa aattatattt
      241 tcagtgccag acaagtgatt tatattgagt tgataaaaaa gatctccatc taaaaaaata
      301 tcattagaag aagatttccc cacagtaatg accattccat cagctctatg tgttacatac
      361 aaataattgt atgacctcat ttcacctaat gaatcaatta tttcttgccc tttagctcta
      421 atatattgat ctctattacc tatctcactc ttatttaaca aaagtttttt catgtcaaat
      481 ttaatcggct gttttatttt tgtaaattcg cttctactac taatccaatc cgagattaat
      541 ttttcaacat gtcccagagt aaactctgat ttattcgcta aatacttttt ttgttgtatt
      601 aaagacatct ttccccgaag ctcaaaattg agcctacatc gattctctat ctcttcaaaa
      661 agcatcttat cttcatcatt cttatattca tcattcataa aaccaatcca gctcctcgat
      721 taagataata ttttaatctc atacaaaaac tagctctcat caaaacaacc attgttttga
      781 tttctcatga aatttcttta tacttttctc cgattataaa ttcctaaccc cttgagaaaa
      841 ttacgcatat atttatctcc gcaaggctta aaatttcgtt ggccttcttt tctcaaaaat
      901 gccccgattt cgccttttga tggatagatt tctgcctcag caaaaacgtc taaaatatca
      961 tcagtggtca tagacaaggc gatttttaat ttttttagca acacattgtt gatatatttg
     1021 atttccttgc ttttttgcgg cgtgtctact atcggcttat ctttttgcgg accacgcgcc
     1081 aagagaatca ggccatttag gaatgcgtca aaaacttggt tgttgatggt tttttcatac
     1141 acattatttt ctgcattatc tttgttctta tcctgtactt tggtcagtac cgcctgagct
     1201 tcttctttag tcagtggtac accgcctagc tcaaaagctt taatcaaatc cgtatctttc
     1261 aaatcaatcg cataacgcaa tcgcaataac ctatcattgt tattcatttg ttcctccgaa
     1321 gtatttagtc tttactttct tacgtacttt ttgtcttgct aagattttta ggatcaatga
     1381 taaaaaccgc atcacttatg ataaggcgct gggtatcatg agtgaatgat attgctgaat
     1441 acaaatagtc cgaccacatt aagttgatcg gacttcataa gcattttatt gactaatact
     1501 tttttgctta agaattgatt ctaacatctt ttgctaaagt taagcatcct atagttcctg
     1561 cattatctgc taacttaggt gtgacaatgt attcttcgat atttggcgta tcgacatagc
     1621 cgttaattag ttctaaaaaa cgtctttgta ctttcttttt cagatgttct tgttgcatga
     1681 caccaccacc aaaaattata atatctggtg aaagcatcag ggtcgtatta caggcacatt
     1741 gtgcaatata atccgcctcg atttcccaga acggatcttc tatagaaaga tcttgtccct
     1801 tggttcccgt acgcatctcg atagcgggtc cagatgccaa cccttcgaga caatcatgat
     1861 gaaaaggaca agtaccagag aaagtatctc ctgaatgtct cttaactaac gtatgcccca
     1921 tttctggatg gctaaaccct tcaacaaaaa tcccatcttg tatagctcct ccaccaattc
     1981 cagttccaac agtgtaataa acaacactgg ataaaccttt tccatgacct gaaacatact
     2041 ccccgtaaca agcagcattc acatcggttg tccaggcaat tggaatttcg aaatgcttat
     2101 tcaacgttcc aacaaaatca aaatttttcc aggcagtttt tggagtagag gtgatatgtc
     2161 cataggtctt tgattcacga tggatatcaa tcggtccaaa tgaccctact ccaatgcttt
     2221 ctaattgttc tttatagtga ttaaagaaat caattaccaa actcattgtt tcattcggtg
     2281 tagttgtagg aaaactcact ctttctaaaa cctttaaatc atcattgcca atggcacaaa
     2341 caaatttagt cccacctgct tctattgagc catacatttc ttactccacc gtccttttat
     2401 ctaggaattc gttcttccct gtctaatagt ttttcgaaaa actcatgtgg ttccttttgg
     2461 taccaatagg caacagaaga aatatcgtct tgacgctcat aaagcttgat gtcatcattt
     2521 cctagggttt ggaaagtaac acgtaaattt tctttgaaac taatggggtc gggtaaatgc
     2581 cagcggtaca acccatgcat cggtaaagca tcatcgccaa aaccatgaac tggatttgga
     2641 ttaggttttc cagcactaaa ataatcccgg gtgtgatctc ttttagattg aaaaggatag
     2701 cccataaata gcgtattaaa attttgagca tatgcccttt ctccaaagtt ctttttatgg
     2761 aaagcccaag cgccgccaaa ataatcttct gctcctgtag atgttattgt agggaaatct
     2821 tcatctccat ctatataaaa cttaaattct ccttcccccc accagtatct ttccaatgcg
     2881 cacaaagcaa agtaggttcc tacataatac ccagtgcctt tgattccatc aataagggtg
     2941 taatcttttc cttttgtcgt gatgggttca cggttccatt tagcatgaaa atacatcgca
     3001 tcatccggta cttcagtcaa tgcataatta aatgtataaa aaatgtgctt aataaactca
     3061 ggatgttcat tcgttaaagt aatcttagct ttttttcgaa atggcatctc aaaatagcaa
     3121 ttcatccctg atgttggatt cactacgatt ggtaaggaat tcacttcgca tcttgtccca
     3181 aacccattac aaaaaaaatc tcctaatgga ctttctacag aaggagtgga ttcatcatcc
     3241 caataaatac gcaaaattaa atcacgtaag acgaaactcc cagcgattgt tttgtctgtc
     3301 actgtcatcc aaaaatgacg taaaattcca gggccttcca tttctgctaa agtaattgtc
     3361 tctccagcat ttatcggaac agaaggtgac ccttttctcc caattcctag atgactcgct
     3421 gtcattgccg ctttcccttt ttcaccattt ttattttctg gtgaaatagt tctactttcc
     3481 tctcccttgt ggagccatat attatttaaa caattcattt tattcgtcct ctatcctttc
     3541 ttcacttttt tgattattca tatagatgat ttgttgttgt gcctccgcaa taattgctcc
     3601 aatatctaaa ttatcatttc ctaactgcaa agcgattgac attgccaagg gaagattcat
     3661 tcctgcaatt acgtgcactc tgtcagaaat ataggtaaaa aacttttgat ttacacttcc
     3721 tccagccatg tcagttaaaa caattatttc gtctgtagta tccactaact ctttaatttg
     3781 ttcatctata tcatcaattt cttcgacata tgcacataag ctactaattt gattatgcat
     3841 acctgttaaa aactctagtg tctctttaaa accctcagct agtattgaat ggctagcaat
     3901 gatcaatctt ctcataattc aaatcctttt cctttacgct aatattccaa atgcagccat
     3961 aaccatcgca aaaacaataa cgagtagaat caaaatggtc atactgattt ttttcttact
     4021 gagtagataa tatgctgcag cagtaataat tactggaatt aatgttggta aaattttgtc
     4081 caacattggt tggattttca tactaacttc accaaaagtg aatttaagtg gcgttgaaac
     4141 actgataact gaagcaatta atgatccaac tactgttagc cccaatactg aagcagcttc
     4201 agttaaataa ttaatctttt caccgtattc agtaacaatc ttcattccct gcttataacc
     4261 aaattcaaag cctctcattc ggaaaaagaa gattaccatg attaaaatga accataaaaa
     4321 gattcctaca ggattatttt ctaaagccat ataagccgca attgatccca tgatggttgg
     4381 gatcatcgtc atcaaaagag agtccccaat accagcaatt ggacccatcg taccaacttt
     4441 aaagtcatta atcgcatctt ttgcttctaa tccttgcttt tcctccattg caacacaagc
     4501 acctaaaata atggctgcca gccaaggctg tgtattgtaa tactgaaagt gattatttaa
     4561 agcttcgatg tattcatcat catctttgta taattttctt aaaataggtg acaatgcgta
     4621 agtcacagat gcaccttgct gtgtttgata attaaaggta caaactgaca tcaaccaacg
     4681 atagttcgct ttcctaagat cctttttcgt tacttgatat ttttcgctca ttttattcat
     4741 cctccccaat aaacccaaca tcagaagctc ccgcagaagc agtgatttgt gcatcttttt
     4801 cagctctatg atacacatta aatgctaaag cgaatcctat gatcgccgct ccaataatag
     4861 gtaccttcaa aaaagcggct aagaaaaatc caacaagtaa ataactaatg tatcgacctg
     4921 taggcataaa gcgtaacaac atcgcaatac caacagcagg caacattttt ccggctaatg
     4981 ttagcccatc cataaaccaa ttaggtaaaa catccaaaac gtaattaaca gcagactgtc
     5041 ctaaagtaac ggcaataaat actggaattg ctgcagataa accaaagaaa attggcccca
     5101 accacaaaac actattcatt ttcttaaatt ctcgtttatt cgcatattcc tgtgatttgc
     5161 gaacaacaaa accatttaag attttgacaa ttacatctag ttgcacccct aacataccta
     5221 caggtagtcc tattgctaat ccggcttcta ctccaagctg gctaccaaat gccgttgcaa
     5281 taattgcgca cgttccatag tccggtacag atgagccacc aaaaccggca actcctaatg
     5341 acatcaattg aactgtaccg ccaactatca aacctgtttt tatatcaccc atcaaaattc
     5401 ctgtgaataa tccccaaaaa actgcgtaat ttacaaagat catcggaatc ccataataat
     5461 caacatgttt aataaatgct aatatagtca gcataataat ttgaaaaata gtaaaatgca
     5521 ttatccttac tcctttatcc taattttgat tgaatttcct gtgccttatc cgccggaaca
     5581 aattgtgtaa caatttctac accagaatcc aacaattttt tatacgtgct gatattttca
     5641 tctgatgcat aggctctaga agatagctgt aatgcattat ctttaacaac agtaccgcca
     5701 acaattagtc ggtcaattct aataccgtta tctactaaat gaaggattgt ttccggctct
     5761 ttcacgatga caaatacttt ttcctgatcg tatttcccct ttttaaaatt cgcaatcgct
     5821 gtttcttcag tgataattga tacagccatt ccagcaggtc tagctaaacg catacttgat
     5881 ttttggatgt cgttatttgc gacagaatca tcgatcacca tcactctgtt tgctttagac
     5941 attggtgccc attgcgtgac aataatccca tgcaataaac ggttatcaac tctcgacata
     6001 acaatactca taaatacttc ctcctttatc tttcattttc ttacaagcaa ttaccatgcc
     6061 aaaacaaaaa gaacttgata aatcaagctc tttttacata atcataaacg tatttaacct
     6121 catgaatcgg gatgtcgaca ctataataat gttcaacgac actgaaagat tgcttaaaat
     6181 gtgtctgaaa tttttgaaat tcctcactcg tttcattgaa ataaatttca tcttccaaag
     6241 tattttgttt tactaatcgt tcaattaagc aactaatgtg aacatataat ccgaaacacg
     6301 tattattatc aaatgaaatt cctagatcat tttgtaagat gtatatagca tctgaaaccc
     6361 gttctaataa tttagtcgga tttaatatgg tcaattgctc cattaaattc gttagactaa
     6421 aattcttcag aatattattg ttcaaaactt tcagttcatt atcattaaag tgtctattca
     6481 attgattgga gaatttactt atattcattc ctaaaatcat atcttcaatt gaaaagaatt
     6541 ctacatcttc tagatgtgga tttagtgttc caacaataaa aagaatattg ttctctttac
     6601 gaagctc
//
LOCUS       DAFKHN010000116         6566 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFKHN010000116 DAFKHN010000000
VERSION     DAFKHN010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.116"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..652
                     /locus_tag="LY912_002620"
     CDS             <1..652
                     /locus_tag="LY912_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956253.1"
                     /translation="LSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQFIRQNLTMSK
                     LFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYLFEVGFILTL
                     FGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTSIHEVTVKGI
                     RSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPYVLGKVVI"
     gene            696..965
                     /locus_tag="LY912_002621"
     CDS             696..965
                     /locus_tag="LY912_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956254.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1197..1493
                     /locus_tag="LY912_002622"
     CDS             1197..1493
                     /locus_tag="LY912_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956255.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1495..1917
                     /locus_tag="LY912_002623"
     CDS             1495..1917
                     /locus_tag="LY912_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956256.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1936..3528
                     /locus_tag="LY912_002624"
     CDS             1936..3528
                     /locus_tag="LY912_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956257.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            3549..3869
                     /locus_tag="LY912_002625"
                     /pseudo
     CDS             3549..3869
                     /locus_tag="LY912_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4030..5171)
                     /locus_tag="LY912_002626"
     CDS             complement(join(4030..4943,4943..5171))
                     /locus_tag="LY912_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBM6956258.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            5419..5613
                     /locus_tag="LY912_002627"
     CDS             5419..5613
                     /locus_tag="LY912_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956259.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
     gene            complement(5749..>6566)
                     /locus_tag="LY912_002628"
     CDS             complement(5749..>6566)
                     /locus_tag="LY912_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBM6956260.1"
                     /translation="TRYQLIKQLIRTKQHFLENLTYKCNTLAREMRDESTSLFSATLI
                     SLMTEDFTLDELAELPLEAFCDLLQEKGKGRFKQPEKIAKAIQRAITMSYRLGALAQE
                     SINVVLSVLVREIRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEI
                     GQIERFEDQTKLAKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYL
                     PEYKAFYQSKYKEVPKHQHKRALVLTARKFTRLVDTLLRKHQLYTPPRNVIEK"
BASE COUNT         2246 a         1053 c         1314 g         1953 t
ORIGIN      
        1 gttaagtgag ccaaaacaga tcgcggcgtc aaatattttc acggcagtaa tgacattaat
       61 gtgtgtcatg tgcttttcta tttttagtta cttactcgtc caatttatca ggcaaaattt
      121 aacaatgagt aaacttttca aaagtttatt ggacttactt atcttaggca gtatgttaac
      181 gactctaaca gatcggttcg aacaatctga aaaaacggta gaggggataa agaacttctt
      241 aacgacgatt gatcaattta taaatggata tatgtatttg tttgaagtag gctttattct
      301 cactttgttt ggttgtgtat ttataaaact cattaaaaga tcaatcgaaa aagaaatggt
      361 tattgatcta attccgacgc tgagcggcta tgagtattac gttgattttg gaaagtatga
      421 ggagttgatc catacggata tcgttcacac gagtatccat gaagtaaccg ttaagggcat
      481 cagatctact ttaaaagatg gacaggagac gaaaacaatc gaccgaagaa aagaggtcta
      541 caatttttat aaagttgaag caagtctacg atatggcatt gggaaattga ggttagatgg
      601 gagtaatatt caacaaaaca aaccatatgt tttaggaaaa gtggtgattt agaacttcct
      661 atgaaagatg aataaataag gagaatcttt tgaaaatgat tcttctttac agaattgtgc
      721 ttatagttgg cacggagtta aaaatcttaa agaaggagca gttattcaaa gtgaaagaac
      781 atcataatca gttactatgt attaaaacgg gtacgatgaa cattcaatac cgaacagaat
      841 atttagaatt aacgaatcaa actgattttt tgtcgattcg agagcaacat aagcaagaaa
      901 aattaatggc tacttatagc caattgattg atgagtggga acaattcaag gaatctaaaa
      961 cataaaattc catttaaaca ccttattttt taaagagcat aaggaaacgt gaccccactt
     1021 ttaaaaaaag tggttggata ggctgtgcct atcacgtttc tgaaaaaaat aaatgacccc
     1081 aaaataccaa tatataggat agtacaagga tagcaaagga tagtaaaagg atagaggtag
     1141 gatagcgaaa aggataggat ccttttcact atcctatatt atattggagg atatttatga
     1201 atgttaaaat tagagattta gatccaaaat tcatttctga aattgatcga agatgcgttg
     1261 aactaagtaa tcgtacagga aataaatgga gtcgtaatga ttatttaaag ctactcgttg
     1321 aaaatgattt tgatcgtcct ttgatggaat acaaacaaga aaagtttgac cagttattag
     1381 aaaagttttc agaaattcaa agttataaca caaagatatt agaagaatat gttagccaaa
     1441 ataatcgtat tatagaaatc ttgattgagc aaaatagagg aagtgaactt tgatatggca
     1501 aaggttatag acaaacacat ttactttcac caaacacata tcgatgtatt ggatgaaact
     1561 atttctactc atgcagaggt taaaaactat agtgaagctg ttcgcttttt atgtatgaac
     1621 tatgatccag aagtggagaa aaaagtaaat tccaatcaag caaagttgaa tggaatgagt
     1681 aaagaaattt ctattttaac cgaaatggtt tcagaatttg cggatcttca tttgaaagat
     1741 acaggaatat taattggtaa aaattcaact gtttatcaag aagcaaaaga acgagtggaa
     1801 ggaaaaatta aatccaatca aacaaaaaaa tattcccctc agttgaagaa acctgtgaat
     1861 gaatctgttc atgccagagt agatccattt gatccaacga agattctaaa aagataaaaa
     1921 tgaaggagga taataatgac tcaatcgcct tcagttattc tcacttgtca atttactttg
     1981 ccgaataaaa agtcattttc tacttatatt gactatatta caagggaaca ggctcttgaa
     2041 gaaaaggaac gacgtacgcc cgaagaagaa caggaacttc aacgaatcaa gaatgcttta
     2101 gaggagtttt atattcctga aggagaaact ttttcggaga gtaagacggg taaagaattc
     2161 agtgaaacgt cgaatgaagc tcaatcgttg atggaacatg gaatcaattt tgacaagtta
     2221 gaggaacaag attttaccaa ttatctttct tatatgacac gtcactatgc gttagaacaa
     2281 aagaaagaac tgacgcaaag tgaacaaaaa gaataccaac gcttgaacca agcaatgaaa
     2341 aaatatcaaa cagaacccca taaaaaagct tcaggaaatc ttcctggagt tttttctata
     2401 gcttcagacg aagtgaaagg aagtgatctg aaggagatta agcaaatctt ccaaagagga
     2461 caacaaaaag gctcaatcat ttatcaagat gttgtttctc atgataattc gtatcttgaa
     2521 aaaataggat tgtacgatcc caaaacagat actttagatg aagaagggtt aaaagcagct
     2581 ggaagaaaaa tgatggagac attattcgag aaagaacaat tgaatgaaac aggttactgg
     2641 atggcaacga ttcaccgtaa cactaaacat atccatattc attttgcagt tgttgaaaaa
     2701 gaaaatacgc gtaaacctta cacggaggtt gaaaatggtg tgagttatat cgtaccgaaa
     2761 ggtaagagaa gacaagcaac attagacgca atgaagacca attatgtaca tgagttagaa
     2821 cgtttttctt atgaaaagga tcgaatgatt ggtatggaga aacgaaattt attgacgcgg
     2881 aaaagtgatt tgcgtaacac cttaacaaaa gtggtaaaag agccagcgcg ttacgatcga
     2941 cacgcgatga acttattaaa tgaagtatat aaaaccctac ctgacaaacg ttcggaatgg
     3001 aattacgggg atgaaaaacg aaccaaactt tcaccataca caagagagaa actcgatgag
     3061 ttaaccaaat atgttttaac aaaagaacct gaatatcaag aatatataca gatttcaaaa
     3121 gcattgaaag aagaagcaaa aagtctttat ggggaaagca agagagaatc aaaggatgca
     3181 gagaaaaatg ctctctttga tttaaaaaag cgcacaggaa atgccatcct aacagagctg
     3241 aagagacagg atagtcaaat aaaaccatta atagaaagtg ttgatcagat gcaatctatt
     3301 tacaatgaac gatcctttcg aacgcttaaa caattgccaa cgaatgaata caaatatagt
     3361 tacgaagaat tcatgaagcg caggaaacaa ttccaacaaa gagttgtcac gcagcggagt
     3421 ttgcgtcaat taaatcgaac gattaatgcc catgaagaaa aataccacgc aagtaaagca
     3481 tacgaagagc aacaacgaag aattcaaatg gaacaagaaa gacagtaaag acagtaggag
     3541 gaatagcaat gaaacaatat ttagatcaat ggaaagttat agaaggatca ttaagagaag
     3601 aacgaatcga acaacttcct gattgtttag aaaaagagca tttgttccag ataagagaaa
     3661 tgttgagaaa cgaacagttt gatccaaatc aatttttagt cgttgagtac ccagctactg
     3721 gtgtgtattg ttgtaatcat gtgaatggtg aaaaatattt tatcattcaa gaatatgagg
     3781 gcaagttagc accttattat actacttggg aaatgaatga agagggaatc aataactttc
     3841 catgtaaaag cattggattt gagtcaatac ctcggacacg atttgtgaga attttttcga
     3901 gattccagcg ggtgagtatc tcatcgtttc gaccagcggt caaaccaaaa ccgtttgacc
     3961 gctgatcgaa gcgatgaagt tgaaaccctg tggaaatctc gccaaaaaaa tgtaagtggt
     4021 agctaggaac taagcttgca atgccaactc ctccatctga tttggtgtta aatagttgat
     4081 actactatgg attcgcttgc gattgtaaaa tccttcaatg tattgaaata acgctaaata
     4141 agcagcttca aagttttcat acgcttttga tggatagact tcttcttttt tgagtgaggc
     4201 gtgaaacgat tcgataccgg cattatcgta gggacagccc ttacgactga aggagtgccg
     4261 aatgttcaat tcattcagct ttgcctcata ggcttcgcta gtgtactgag aacccaaatc
     4321 tgagtggatg atcaagttct cggagggtgt ttggtttaag agcgcattgt caagggtttc
     4381 gataaccaat tctttcgtca tctgcttgcc aaacttccaa ccgatgactt tctttgtgtg
     4441 gaggtcttga atagtggaga ggtaggtcca gccatctttt agggtatgaa tataggtaat
     4501 atctgtcacc catttttgat tgatcgacgt agtggtaaaa tcttggttta acaggttttt
     4561 acgtccttca cttttaactt tcgcttgttt gccaggcttg tacttcttga gggtgactga
     4621 acgcaagcct aattttctca tcagtatttg tactttcttt aaggacaagg tctcgccacg
     4681 gccaacaaga atcttatgaa ttttaggcgc accatagata cccttgtttt caaagtagat
     4741 tcctgaaatc aagcggttta agcgtttgtt ttctgattgg cgcttggaag gtttcttttt
     4801 cttccagtca tagtagctgg atttcggtgc ttccaaaacg gtacacattt gttttacgtc
     4861 atgatcatga acatttgatt gaataaattc gaagacatca ctcattttta cttttgagcg
     4921 aatatggtta aagccttttt taggatagtg ttttcctcct gcatgcgggc catttccttt
     4981 ttcatcgcta ggatttctgc ctcagtcatg ccggttgcta cattctttgt atgaagcttc
     5041 ttccaacgat aaatcgtttg tgtagcgata ccatattgcg ctgccagttc ttcgaccgat
     5101 tggccagact ggtttaaatc taagatcatc ttcttaaagt cttcatcaaa ttttttcttg
     5161 gcttttgcca tcgtggacac gtccttttct tagtagttag attctaccaa atcgtgtcca
     5221 tgaaatcatc ctaacatcac attgaagagt ccatttcact cacagagtgt tagttgttaa
     5281 gtgaataaaa gaagtaaaag agtcctgaac gtgattgtcc aggactcttt ttttcaatga
     5341 attgttttcc gccaactcat tgagtggtgc gatttgcgac tacattatat caaaagaaag
     5401 agaagggagg aagcagaaat ggttcattca acgattggag ttgttgttga aaaaagcaga
     5461 gacaatctcg tttttgtgac agaaattcaa acaggcagat cttttgtcgt cacagacaaa
     5521 gcggcaaaag cttatcaaag tagcgatatt ttaacgttaa atctgactac gaagacgttc
     5581 gtcgatgcga cagaagatta tccatttgtt tagtctaatg gtgataagtc aagatgaaat
     5641 ttaagatttt ctttattgag taatatgttt tgaagcgcac gaaactagac ccgatcaaaa
     5701 tcaaattttt ttcgggttga ttcaaggatt tgcgtcaata acggattgtt atttctctat
     5761 cacattcctt ggtggcgtat agagttggtg tttacgtagt agcgtatcca ccagacgcgt
     5821 aaattttctt gcggttagga cgagtgcacg tttgtgttga tgctttggaa cctccttata
     5881 tttactttga taaaaagctt tgtattcagg aagataattt tttacagagt tggcagcttc
     5941 aactaagtag tatctaaaat atcgatttcc ttgttttgtc agaggtgtat tttgcgactg
     6001 atagtttcca gattggttca ctttccaact taatccagcg tattttgcca attttgtctg
     6061 atcttcaaat ctttcgattt gaccaatttc agcgattaaa ccggcagcat agactttacc
     6121 aacgcctgga atactggtta agcattgata ttctggaatg acaacaatta cttgttcgat
     6181 ggctttatct aattctttga tatttttttc aagtgctcgt atttctcgta cgagaacact
     6241 taaaacaaca ttaattgatt cttgtgcaag agcacctagg cggtaactca tggtaattgc
     6301 acgttgaatt gctttagcga ttttttctgg ttgcttgaaa cggccttttc ctttttcttg
     6361 aagtaaatca cagaaagctt ctaaaggaag ctcagcaagt tcatccaatg tgaaatcttc
     6421 cgtcatgagt gaaatgaggg ttgcactaaa aagactcgtc gattcgtctc gcatttctcg
     6481 agcaagcgta ttacatttgt acgttagatt ttcaagaaaa tgttgctttg tacgaatcaa
     6541 ttgcttaata agttgatagc gagtac
//
LOCUS       DAFKHN010000117         6559 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFKHN010000117 DAFKHN010000000
VERSION     DAFKHN010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.117"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            38..126
                     /locus_tag="LY912_002629"
     tRNA            38..126
                     /locus_tag="LY912_002629"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72..74,aa:Ser,seq:gga)
     gene            141..212
                     /locus_tag="LY912_002630"
     tRNA            141..212
                     /locus_tag="LY912_002630"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:174..176,aa:Glu,seq:ttc)
     gene            228..300
                     /locus_tag="LY912_002631"
     tRNA            228..300
                     /locus_tag="LY912_002631"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:261..263,aa:Val,seq:tac)
     gene            310..382
                     /locus_tag="LY912_002632"
     tRNA            310..382
                     /locus_tag="LY912_002632"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:343..345,aa:Asp,seq:gtc)
     gene            418..493
                     /locus_tag="LY912_002633"
     tRNA            418..493
                     /locus_tag="LY912_002633"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:451..453,aa:Phe,seq:gaa)
     gene            495..575
                     /locus_tag="LY912_002634"
     tRNA            495..575
                     /locus_tag="LY912_002634"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:529..531,aa:Tyr,seq:gta)
     gene            582..655
                     /locus_tag="LY912_002635"
     tRNA            582..655
                     /locus_tag="LY912_002635"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:614..616,aa:Trp,seq:cca)
     gene            658..730
                     /locus_tag="LY912_002636"
     tRNA            658..730
                     /locus_tag="LY912_002636"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:His,seq:gtg)
     gene            742..813
                     /locus_tag="LY912_002637"
     tRNA            742..813
                     /locus_tag="LY912_002637"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Gln,seq:ttg)
     gene            859..929
                     /locus_tag="LY912_002638"
     tRNA            859..929
                     /locus_tag="LY912_002638"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:891..893,aa:Cys,seq:gca)
     gene            950..1034
                     /locus_tag="LY912_002639"
     tRNA            950..1034
                     /locus_tag="LY912_002639"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:984..986,aa:Leu,seq:caa)
     gene            1096..1168
                     /locus_tag="LY912_002640"
     tRNA            1096..1168
                     /locus_tag="LY912_002640"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1129..1131,aa:His,seq:gtg)
     gene            1178..1249
                     /locus_tag="LY912_002641"
     tRNA            1178..1249
                     /locus_tag="LY912_002641"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1210..1212,aa:Gln,seq:ttg)
     gene            1267..1351
                     /locus_tag="LY912_002642"
     tRNA            1267..1351
                     /locus_tag="LY912_002642"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Leu,seq:caa)
     gene            1606..2481
                     /locus_tag="LY912_002643"
     CDS             1606..2481
                     /locus_tag="LY912_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBM6956261.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            2585..3349
                     /locus_tag="LY912_002644"
     CDS             2585..3349
                     /locus_tag="LY912_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBM6956262.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            3336..4778
                     /locus_tag="LY912_002645"
     CDS             3336..4778
                     /locus_tag="LY912_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBM6956263.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            4789..6119
                     /locus_tag="LY912_002646"
                     /pseudo
     CDS             4789..6119
                     /locus_tag="LY912_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            6132..>6559
                     /locus_tag="LY912_002647"
     CDS             6132..>6559
                     /locus_tag="LY912_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBM6956264.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEV"
BASE COUNT         2064 a         1083 c         1452 g         1960 t
ORIGIN      
        1 ctcattttga gaaagagtat tgagcttctt tcactctgga gagttgtccg agaggccgaa
       61 ggagcatgat tggaaatcat gtagatggtg caaactgtct caagggttcg aatcccttac
      121 tctccgtagc aaatttacct ggcccgttgg tcaagcggtt aagacaccgc cctttcacgg
      181 cggtaacacg ggttcgaatc ccgtacgggt cattttaatt gaatgttgga ggtttagctc
      241 agctgggaga gcatctgcct tacaagcaga gggtcagcgg ttcgatcccg ttaacctcca
      301 taatgaactg gttccgtggt gtaggggtta acatgcctgc ctgtcacgca ggagatcgcg
      361 ggttcgattc ccgtcggaac cgtcgttctt gttattcaat taataatttt aaaatatggc
      421 gcggtagctc agttggtaga gcaacggatt gaagctccgt gtgtcggcag ttcgattctg
      481 tcccgcgcca ccatggagga gtagcgaagt ggctaaacgc gacggactgt aaatccgttc
      541 cttagggttc agtggttcga atccactctc ctccatttta taggggcata gtttaaaggt
      601 agaacagcgg tctccaaaac cgttagtgtg ggttcaattc ctgctgcccc tgccatggcg
      661 aatgtggcga agtggttaac gcaccggatt gtggctccgg cattcgtggg ttcgattccc
      721 atcattcgcc ctttttattc ttggggtata gccaagcggt aaggcaaggg actttgactc
      781 cctcatgcgt tggttcgaat ccagctaccc cagtttctat aatttattct ttattttgta
      841 gattgataat agtataatgg cggtatagcc aagtggtaag gcagaggtct gcaaaacctt
      901 catcaccggt tcaaatccgg ttaccgcctt agtactaata aatcaacttg ccggcgtggc
      961 ggaattggca gacgcgctgg actcaaaatc cagtgcccgt tgagggcgtg ccggttcgac
     1021 cccggccgcc ggtattgact aagatgtctt catcttagtt ttttattgag aaattaaata
     1081 acatctttta tgatggcgaa tgtggcgaag tggttaacgc accggattgt ggctccggca
     1141 ttcgtgggtt cgattcccat cattcgccct ttattcttgg ggtatagcca agcggtaagg
     1201 caagggactt tgactccctc atgcgttggt tcgaatccag ctaccccagt tattattttt
     1261 aaatttgccg gcgtggcgga attggcagac gcgctggact caaaatccag tgtccgttga
     1321 ggacgtgccg gttcgacccc ggccgccggt ataattatca atatagcaac tttcttatag
     1381 agagttgcta tatttttttt gtttttatgt aattacctcc aaatcaattc gatacaagta
     1441 ttatcataaa acgagtaaaa aagatattga taacgctttt attatgtgtt aaactatttt
     1501 tgtaaattat gtagggtgct actattcaat taggcacgac ctaagaaagg gttctttctt
     1561 aggtcgtttt ttgtctttaa aaattgtttg gagacaaaaa tatgtatgaa ggagtctgca
     1621 agttgttttg ttttatcata tagtggaggt gaattaacgg tgtatgtgat gaaaaagctg
     1681 aatcataatg ctgtattgat cgatgacgat ggaatagaaa aaattgcgat ggggaaaggg
     1741 attggctttt ctgctaaagt gagtaagcca tttgatgttg aggatgctga caaattattt
     1801 gtattagatt ctaaagaaaa gatcaaacga ttcagtgaga tagtctcgca gattccaatc
     1861 gaatttatgg attttgcgga agaagtgatt gaactgataa cagctaggat ctcctctcca
     1921 ttagattcaa atatctatat tacattgaca gatcatattt attttgctat tcaacgaaaa
     1981 agagaagata gagatgtcac agcaattatg ttgccagaaa tgagattcct ttatccaaat
     2041 gaatatgata tagcaataga agtggtcgag cgaatcaatc atcgatatca aaccgagtta
     2101 gggtcaaatg aagtaggatt catcactatg catatcatta atgctgagct aggagagcct
     2161 aatagtttaa agagcttaaa aatagtagaa atgacgacca cgattttgtc ccatctagaa
     2221 aaatcctatt caaacgttta tgataaagaa tcactgactt atcatcgctt aatggttcat
     2281 atcaaattcc tggttaaacg cttgatttat caggaagaaa cgccagtaga aaatattggt
     2341 ttttttactg aaacatttaa acatagcaaa gcgtattgta cagcactaaa gattaaagat
     2401 atcatcgaac agcaatttca acttgccatt caagaaaatg aaatcatcta tttggcaatt
     2461 catctagcac gaatctatta aaataagggc gtaactatct ataggcgcaa ccaaatgaca
     2521 catagtaaat ggactatgat tatttggttg cgcctatttt agtagaaaaa agaaggagaa
     2581 tgaaatggga aaagtgattt ttaattcgga tgattttggc tatagccatg gtgtgaatta
     2641 tgggattatg gatgcttatc agcgaggaat tttgacatca actacattga tggcaaatat
     2701 gccgggtttc gagcacgctg tgaaactaag aaaggaaatg cctaggctag gtgtaggagt
     2761 ccatttaaca ttgacgtgtg gcaaaccact tctcaaaact gtcgatactc ttatcgaaag
     2821 cggagagttc agatccttat cttattatca gcatccattt aacattgaca aagatcaact
     2881 gtatcaggaa tggaatgctc agattcaaaa aatttatcat gcggggatca taccaactca
     2941 tttagacagt catcatcata ctcatacttt ggatgaaaac caggaggtag ttgttacatt
     3001 agcaaaaaaa tatgatttgc cggttcggag caactttgaa cgaaaagatg aagttcgtca
     3061 tgtcgattat tttgagcctt gtttcgatgt cgtaggagaa actgatgaaa aaaaacgaca
     3121 aatcaatacg agtgtggaag aatatttggc aagtttactc atgatattga gagaagataa
     3181 aacgatcgaa gtcatgtgtc acgcagcgta tttggatcag gaattgttaa atggttcaag
     3241 ttttgtgtat cctcgtactc accaagtcga atttttaatt cattcagcat ttgctcaaaa
     3301 agtgaaaaat gatcctttga ttgagttagt aacatatgag gatatttaat agaggaggaa
     3361 taaaaatgaa tgttaaatca aatgtgcaga agcttggaag agcgatgcta cttccagttg
     3421 cagcgatgcc attagcggga ttgatcatgc gtttatcagc tgatgatatg ctgaacatcc
     3481 cagtaattgg tgcagctgga aatgccgttt ttggaaactt ggatatctta tttgctatag
     3541 gagttgcaat cggttttgtc aaaaataagg acaaaggaat acctgcactt actggttttt
     3601 tagcgattgc taccttgaaa aaaggcttag aaatcatgga cccagaagtg aatatgggga
     3661 tttttggtgg aattatttcc ggtttagtag cggcatggac gtataatcgc tttaaagaac
     3721 aaaaattacc agtagttttt tcttattttg cgggcgaaaa attcccattg actatggtga
     3781 tgattctaca aacaatcgca gctatttttt tgggctttat ctggccgctc atccaaattg
     3841 ggattgataa ttttgcaaaa ctgctcgttg atatgggggc attaggtgtg gggatattta
     3901 tgtttttgaa tcgtttgctg atcccctttg gactgcacca tgtgttgaat acgtatattt
     3961 attacgattt aggaagctat acatctccta gcaaggaagt tttcagagga gagatgacac
     4021 gctttatcaa cggagatcct caggctggac tgtttttatc aggttttttt gtagtaatga
     4081 tgtttggtat accagctata tgtctagcta tctataaagc agcttataaa gaaaataaag
     4141 agatggtcaa aggaatcatg ggaagcggtg caggaacttc atttattgca aatatcactg
     4201 agcctgttga atttagtttc atgtttcttt ctcctatgtt gtacgtgatc catgcacttt
     4261 ttgccggttt agcagggatt gtctgttact tattcaatat acgaattggt tttacattcg
     4321 gagcatgtat tgttgattat ctcatcaatt ttcgaatcgc taccaatgct attttgattc
     4381 ttccaatcgg aattttcttt tttgccttgt attacgttac tttttattat ttgatcaata
     4441 agagaaacat tcagacatta ggacgtgaag ctaaggcaga gtttggcaat gaagtaacct
     4501 tagaagaaac agagttaggg ttagcaagta aaaattatga atatatggca acaaaaatgc
     4561 tacaagcgtt tggaggaaaa gccaatatcc tggatgtcta tagttgtaat acacgcctac
     4621 gggtagaggt agtggatccc accatggtcg aggaacagcg aatcaagcaa ttagggataa
     4681 gcgggatcat taaaccaact gaaaaaaatt atcaaattat catcggctta gaagtgactt
     4741 atgttatggc agaattcaat aaattattag aagaatagaa aggaaaagat gatgatgaaa
     4801 aaacagatta tcactatagc tggaggcggg agtacgtata caccaggaat cgttcaagcc
     4861 attttgaaca atgaaaaacg gttgccatta tctgaaatac gtttatatga tattgatgaa
     4921 gaaagaaata tggatatgta cttgattgtt aaatttatgc tgaaaaaaaa ggtttttcaa
     4981 atattcgcat tcgtgcaacg gatgatccaa agcttgcttt tacaggatgc gattttgttt
     5041 tctcacaaat tcgtgttgga ggattggaga tgcgagaaaa ggacgaaaag attccactta
     5101 aacatggatt agtaggacag gaaacgtgtg gactcggagg atttgcttat gggatgcgct
     5161 caatcaaagg tttattggaa attgtcgatc atatacaaga ctatgccccc aaagcatgga
     5221 ttttgaatta tacaaatcca gagtcgatcg tttctgaagc tgttcgtcgt aaatatccga
     5281 atgtaaaaat gattaatgcc tgtgatatga ctatttcaat tgaagaaacg attgcagtga
     5341 attacggtta tgatcgtaag aattggatcg ttacgtatta tggtttaaac cactttggct
     5401 ggtatacatc gatttatgat aaagaattgc aacgagaaat tatgccagag attattgaaa
     5461 aactaataac aaaagaaatg caagtcgccg attttaatat aggagacaaa acttggcaaa
     5521 aaacctttca aatgatgtca gtcatcacga aaaattttcc aagtaatatc ccgaataatt
     5581 acttagagta ttacttatat cctgatatgg tcgttgagca tactgacaaa gagtatacac
     5641 gtgctaatat ggtcatggat ggacgagaga aaaataccaa agaaatggct gataaaatac
     5701 gccgcggtat tgtggaagaa gtattgaact ttaattttgg ggagcatgga caatatatcg
     5761 tcgatatagc tatttccttg ttgaatgatg atcgtcgtcg ctttatgcta atcgttccta
     5821 atcaaggggc gattccgaat ctacggtcag atgcagttgt tgaaataccg gcatatgttg
     5881 gtgcaactgg tgtggagaca attacactaa gaaaaccaat cagtgatttt cataaaggat
     5941 tgatggaggc acaagttgca gcagagaagt tactagtaga tgcttacttt gaaggttctt
     6001 atcaaaaagc tttacaagca tttacattga atcaaaccgt accaaatgcc agagtcgcaa
     6061 aaaaaatact agatgaaatg atcaaagtaa acaaaaaata ttggccagca ttaaagtaga
     6121 ggtgataaaa agtgcatttc tttaaaacaa gaaacattct aaaagctgta gctagtggtc
     6181 aaattattcc attaacagca gtaaaagacg aggtcttttc ttcaaaaatg ataggagttg
     6241 gatacgctat aacgaatcat gatggatata tccatgcgcc agttaaagga ataatcgata
     6301 atatatttcc tacccgacat gccataacga tcgaaagtga atctggcaga aaaatactga
     6361 tccatatggg tttagataca gttgaactcg aaggaagtcc gtttcagata cgggttgaaa
     6421 gtaaccagga ggtaaaagaa gggacactgt tagctattat agatttgaag aagttggagc
     6481 aagcacaaaa agatacggtg atcattgtag tttctccagg catttttgaa ggaaatttat
     6541 taaaacaaaa ccaagaagt
//
LOCUS       DAFKHN010000118         6532 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFKHN010000118 DAFKHN010000000
VERSION     DAFKHN010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.118"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            254..592
                     /locus_tag="LY912_002648"
     CDS             254..592
                     /locus_tag="LY912_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956265.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNEQLG"
     gene            702..944
                     /locus_tag="LY912_002649"
     CDS             702..944
                     /locus_tag="LY912_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956266.1"
                     /translation="MVFDREKMLAHANEVLMSGLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTIDRKKGVLQ"
     gene            944..3106
                     /locus_tag="LY912_002650"
     CDS             944..3106
                     /locus_tag="LY912_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956267.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYQKEEKEAKAKK
                     AKVKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEEVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLLIPDDPNMFESEVEEATDFYSAVEQLEVATN
                     GLERLAETFNSSEEVEFEALAEDIPDEKEALFADDDKPTEAENQEVSIEETQTQIQTE
                     TYQQSKIDEKPESQSDKENYVYEVEKIVSESDVPKSLDADFLEKNFEQIIADKFQPVV
                     LDEINDPVDLNEEMLSIAELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGK
                     QMLADELLRIEQATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMA
                     KQAYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQN
                     QEAKEVVVERIINSLKPEIENSLTDVQEKTLEIVEKTKSENEAEFHDTKEKITDVVVK
                     YFANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYRSNSEKLAEQS
                     EALREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTIL
                     GSSYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVIS
                     IDGKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            3118..3351
                     /locus_tag="LY912_002651"
     CDS             3118..3351
                     /locus_tag="LY912_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBM6956268.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            3341..4207
                     /locus_tag="LY912_002652"
     CDS             3341..4207
                     /locus_tag="LY912_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956269.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            4222..6192
                     /locus_tag="LY912_002653"
     CDS             4222..6192
                     /locus_tag="LY912_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956270.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            6359..>6532
                     /locus_tag="LY912_002654"
     CDS             6359..>6532
                     /locus_tag="LY912_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956271.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARV"
BASE COUNT         2514 a          894 c         1272 g         1852 t
ORIGIN      
        1 gggcttatgc tggtaaagaa cagaattatt atctaaacaa aaacttgata aaccagcatt
       61 tttagccaat aaaaaaagtg aaataattta atggaaaatc tcttttaatc atcgaaaatt
      121 tatgttatta tgataacata aagatgtaaa tatcgagacg tctttttctt agttagatca
      181 ttgacaagtg aacaaataag atttgtcgat gatataatta acttattaaa aatattaaaa
      241 aggaggtttt tatatgttcg attctattaa aaatttggtt agcggaatga cgcctgatat
      301 gaaaacttta gtacaagttg ttttgtattt cttggcattc gttttttcgt tgaaaccagg
      361 attcactgca atgaaatttt ttggtgatgc aaaatgggga gatggattaa aatatgttgg
      421 ggcgattatt gcaatcttta ttattcctgt aattacaacc gttatgcttt acacaatggg
      481 tactaaaaca ggtaatgatt tgaaccaaaa agctaatatc atatcagcac ttattccagt
      541 tgttggtatc tatctagttt caaaatttcc aaaaaatgaa cagttaggtt aaaagtgaat
      601 tgaacaaatt tggataatat gccgatttgt tcaatttact ttttaccaca aaactacgct
      661 ccaagcgtag tttagaagtg agggaagaaa gtaaatgtaa gatggttttt gatagagaaa
      721 aaatgttagc tcacgccaac gaagtattaa tgagcggtct gaaaggtacc gaactggcaa
      781 agataatgaa tatgaatgtt aaccagttct atgattatcg gaatgggagt aaaaagattg
      841 aaaaagccag acttgaaacg cttattaaat tcgaaaaagc atatgtatat atgctagaca
      901 aacagaaaag aactattgac cgaaaaaaag gagttttaca ataatggcaa aattcaaaga
      961 tattaccgaa tctattaatt atgtggcaga aacagttcct gtagttgcac tctctttgaa
     1021 gccacaatta ctcgaagtgt accaaaaaga agaaaaagaa gcgaaggcaa aaaaagctaa
     1081 ggtaaaggta tggaaagaat tcgatgcgtt gctgaccaaa gatttaccaa agaaaaatta
     1141 tatggtaatt gaagatgtac aaaagctcaa cagtgaggaa gttatagatg aggatgatgc
     1201 tattctcgat tccgaaaagt atgtcgttct attgaagtca agtttgaatt atgtagctga
     1261 tctaccagaa aaatttaaag agaagctatt agcaggtgtc cgttttatgg atagtagtgg
     1321 tcaattatta cttattccgg atgatcctaa tatgtttgaa tcagaagttg aagaagctac
     1381 agacttctat agcgcagtgg agcaattaga ggtagctaca aatggattag aacgacttgc
     1441 tgagaccttc aactcttctg aagaagttga atttgaagcc ttagcagaag acataccaga
     1501 tgaaaaagaa gctctttttg cagatgatga caaaccaacc gaagcagaaa atcaagaagt
     1561 aagcatagaa gaaacacaaa ctcaaataca aacagaaacc taccaacaat caaaaattga
     1621 tgaaaaaccc gaatcccaga gtgataaaga aaattatgtt tatgaagtag aaaaaatcgt
     1681 atccgaaagt gatgtaccga aaagcttaga tgctgatttt ttagaaaaaa attttgaaca
     1741 gatcatcgct gataaatttc aacctgtagt tttagacgag attaatgatc ctgttgattt
     1801 aaacgaggag atgctatcca tagctgagtt gaaaccattg ctgtttttag ctaaagagag
     1861 tatgaatgct cgtatttcta tcgctaataa taaaatcaac agtgaattaa ataagacgaa
     1921 ggagcaattg atcctcaaag gaaagcaaat gttagccgat gagcttttgc ggatagagca
     1981 agcaacctca ttaaatggtc aaaatcagtt tacaaataca ttatcggttg ctaaagagag
     2041 ctacgaagca gaagcatcta agattgatga tttagtgatg gaaaaatcca gtatcattcg
     2101 taaagattat gatatggcga aacaggctta tttggatgct gaactaaaga aactagagca
     2161 acggtatgat gctgaacatt taccagaagt taaacaacaa gaagatgaat atagaaaagc
     2221 aactgaagaa agtcttgatc aacagtacca agaagcaatt gaatctatta aaaacgatgc
     2281 attgaaacaa aaccaagaag caaaagaagt tgtggtggaa cggattatca attcattgaa
     2341 accagaaatt gaaaactcat taacagatgt gcaagaaaaa acgttagaga ttgttgaaaa
     2401 aacaaagtca gaaaatgaag ctgagttcca tgatacaaaa gagaaaataa cagatgtggt
     2461 tgtcaaatat tttgcgaaca aagaagaagt tgaaaagcaa gtagctaaca acacgaaaga
     2521 attagaaaca aaacttgtag agcaacaaaa aactatcgaa gaatataaag atcgaatgaa
     2581 agaggtcaaa gatttagcag agggttatag atcaaatagc gaaaagttgg cagaacaaag
     2641 tgaagcttta agagaagact tatctcgttc ccgaagtgat ctagctcaaa tggcagaaaa
     2701 aacgaaatca ttagcagttg ctacagaaaa tcaatcaagt tcaaaacgtg attttacaag
     2761 taaaaagatg gctactatca tttctgtcgc tgcaatggct tgcggaacga tcttgggatc
     2821 gtcctacttt attagtcata ataatcaaca agcacaggct caaactcaaa catctatttc
     2881 gagagtggaa aattcgattg ggacaaatac gaactctgct tcaacaaata gtagctatga
     2941 agcaacacca actacagagt tcaaagttgg gaaagatgtt gtcatcagta ttgatgggaa
     3001 aacaactaag gctgaagtga tttctattga tggagaaaaa gcagttgtga aaactccaga
     3061 cggaaatcag tacaaaattc aagctcactt atctgataat aactaaggag ggctattatg
     3121 cgagaagaaa aaatagttta tccagtaatt caaaacaatc aagaaaacat gacctcttct
     3181 cagcacttac aggaagcaca gctcgtgtat caggtaaatg aactaccaca aacgaacgag
     3241 acaatgagca agtcaatatc tttaattggc ttgcttattg ttgcaatagt gataactgta
     3301 ggtgtttacc gtaagttgaa cgtgaaagga agtatttctg atggcagata actcaaacta
     3361 tggatttaaa cataacttac atcaaaaacc ttctgaaaca attgtcagag ttgaatggct
     3421 tgaaaagcat gtcaatagca cctattctgt tacagcaaaa agattaattg tatcagctat
     3481 agttgttgca gtcgttgttc ttggatcaat tgtttactta gtttctgata cgattaaact
     3541 gaaatttatt tttgttccaa cgttattaat gataattgga tttcttattc taattagcca
     3601 gtatatgttt attgatccat ctagtggttc attgatttct ggttctatta gactgttcaa
     3661 atcagtagtt aattcagcaa gagtatctat ggggaaaaag aaaccatttc gaggcacaga
     3721 gattttaaaa gtgaaacaag atggaacaat cgtatatcga gatgggagtg tagcattaat
     3781 gttcaatcta gatggggcta catcactaac cgcttttcca gaagaagtta tggctcagga
     3841 atcgaaatca atacaatatc aaaataccag agatcgttcc ttagctgaaa tcaaaatcac
     3901 ttcatctcaa cctcagaata cggaaagaca aactcgaaat atgaaaatac aaaaacgaaa
     3961 tgcaaggagt aacaaagcag tctttgacat aatagatcag caagaacgat ttgtatcaga
     4021 atatattgat ggtgtgaaaa caacagtaat ccaatatctt atcttgaaat ctcaatctaa
     4081 gatggtattg gatgaaggtg tggaacgttt agaaaactat acgagtagag gactttatta
     4141 tagtgtcact cagttgtcag ctaaacaaac aaaagaaata ttatctgata tttatgcact
     4201 gaaatagagg tgagagatta aatggaaatt atgggtagat cacaactatt aaatttcaaa
     4261 aaaaagagaa aaactaaaaa agaacaaaaa actagaaatt caaaggtagt gaataatacc
     4321 tttgttagtg atttaacatc tttagttggt tatcaattta caccatctta cattaggaca
     4381 ggtaagcggt ggggaacaat tgtgaaatta gtgaatactt atggaatgaa tagaaattat
     4441 ggatttggtt ggatggttaa agctattcct gaagtgagag tagaaggggt aaaagcctat
     4501 ctaattgaag cagataagcc agtgtcacaa aaagatcaac aagaaataat gcacgagaat
     4561 gttgggggat caacgaatag ttatgaaaat aatttagaag gaaaaaattc agatgctgaa
     4621 attagcaaaa ctgttatgcg gattatggat ttgaatacag catctttact agacagcatg
     4681 gcaaataaaa ttattgattg gaagctagaa atcctattag tatccgattc tcctaataaa
     4741 atcagcgaac agctaattaa actccaacgg ttgtatgatg aaaaaatgta tggattaaag
     4801 cttatgtcat atggaggaga tcaacgtgat ctgtttgata gacttttaag tgaaccaatc
     4861 gggaatgtct atgagtatac gtctatgagt tcggattttg caggaaatga tcatgcaatt
     4921 cgcaaaggtt tagatgatgc gaatggatgg gctatcggca ctatgtctac tagctacgca
     4981 agtggtgtag cttttatggc actggatgat tcttttacaa gtaaagtttt agtggcatca
     5041 cacaaaaacg ctacaattaa aggctatgat gaaaaaatct cagcatcatc actttggggg
     5101 caattgattg ctaataatgc aatggcaaat cataaacgaa cttttcatat tgtcttaaat
     5161 aaatttgatt actttggtga tccaactggt agaacatttg ttgccaaacc ttcgttaaac
     5221 agtgtaatag aaaaggttaa tttggctgaa gaaggtctta actctttgga gctttttggt
     5281 aatcaaaagg acattggtga tttatataga cggaatctcg ataaactaac tcagattttt
     5341 tatttgttag caggcagaac attagattct gcaactagag ttttattgaa aaaagaatta
     5401 ggtaactttt atataagtca gaaactttgg gatattaatt atgaagaacg ttcaaaactt
     5461 ttggtgaaca gtagtgatac aatgccagtt cttggggatt ttattagcta tttgactaat
     5521 gctgaaacaa aagccaaaaa atctggtact gaaaaagaag tcgatcgtat tattgtatta
     5581 aaagacacat tgagaacagc attagacagc ttctctagga tgtttaatca aagaacgaca
     5641 ctgaaagaaa tcggtaaaag tgacaaatta cagttttact ataacttagg tgatctaaga
     5701 gcagaaacca atgttatgga agctcaattt ttaaatacct ttgatttcat cacatcacaa
     5761 gcaaaaaaag atgatattgt tatgattcac ggcttcgata agttatctat tgaaaccgtt
     5821 gggctaatta aaaaaagatt aacaatgctt gaagaagatg gaattcgtct tgcctttcta
     5881 tttgatacaa tcggttcagg agaagacaat gaatacaaag aagatattga aacagctgat
     5941 atattcaata cagatggaaa aatttaccaa agttttgaaa gtgattttaa ttacactatc
     6001 attggaaaga tgaccagtgg agagttaatg aagtatgaaa aaaaagttgc tcctgctaga
     6061 aaaggagaag atgatcaaaa actttctgtt gatttgagac agtatttgac aacaggaaga
     6121 agtaataaat ttcagatcag gagaccagtg gatctgacta ataattttgt tattggagag
     6181 tttattcttt aagttttatc tttgattttg agtgtataag gaaaggataa gaaaaaacat
     6241 gtatatttga gactaaaaac agtcttagag aacatggtac gttttgtgaa aagagaacta
     6301 tagaaatttc ataaagtgaa accttactga gtgaaataat tatagtggag gttaaataat
     6361 gaaaccaaac ataaaaattt tagatcgaat atttctaggt agagacacag aagtaatcct
     6421 aattcaacat gaagaaggat ttgaagttag tataggtatt cagaaacttc aaaaacctca
     6481 ttattgtaat cagttgtata aaaactttac tgatgaagaa aaagcgagag tt
//
LOCUS       DAFKHN010000119         6475 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFKHN010000119 DAFKHN010000000
VERSION     DAFKHN010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.119"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(99..1229)
                     /locus_tag="LY912_002655"
     CDS             complement(99..1229)
                     /locus_tag="LY912_002655"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBM6956272.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="LY912_002656"
     CDS             complement(1878..3080)
                     /locus_tag="LY912_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBM6956273.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="LY912_002657"
     CDS             complement(3140..3343)
                     /locus_tag="LY912_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBM6956274.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="LY912_002658"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="LY912_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="LY912_002659"
     CDS             4880..5692
                     /locus_tag="LY912_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6956275.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1955 a         1317 c         1013 g         2190 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaa
//
LOCUS       DAFKHN010000120         6198 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFKHN010000120 DAFKHN010000000
VERSION     DAFKHN010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.120"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            207..725
                     /locus_tag="LY912_002660"
     CDS             207..725
                     /locus_tag="LY912_002660"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBM6956276.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            853..1536
                     /locus_tag="LY912_002661"
     CDS             853..1536
                     /locus_tag="LY912_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBM6956277.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1845..1918
                     /locus_tag="LY912_002662"
     tRNA            1845..1918
                     /locus_tag="LY912_002662"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1879..1881,aa:Arg,seq:tct)
     gene            2077..2436
                     /locus_tag="LY912_002663"
     CDS             2077..2436
                     /locus_tag="LY912_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBM6956278.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2559..4190
                     /locus_tag="LY912_002664"
     CDS             2559..4190
                     /locus_tag="LY912_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBM6956279.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4252..4893)
                     /locus_tag="LY912_002665"
     CDS             complement(4252..4893)
                     /locus_tag="LY912_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBM6956280.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5079..5155
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5175..5483
                     /gene="rplU"
                     /locus_tag="LY912_002666"
     CDS             5175..5483
                     /gene="rplU"
                     /locus_tag="LY912_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBM6956281.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5510..5854
                     /locus_tag="LY912_002667"
     CDS             5510..5854
                     /locus_tag="LY912_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBM6956282.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5867..6160
                     /gene="rpmA"
                     /locus_tag="LY912_002668"
     CDS             5867..6160
                     /gene="rpmA"
                     /locus_tag="LY912_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBM6956283.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         1953 a         1023 c         1310 g         1912 t
ORIGIN      
        1 tattcctttc taaaacttgt aatgttaggg taaacgtttt ttaaactaac gtcaattatt
       61 tataataaaa aatgagataa agatgaggaa atagaattag aaacatataa ttattaaagg
      121 gaaacatttt tacagctata atttgaaaaa aatttatcgt tattatatga ttaagaagga
      181 ttgaataaag aaagaagttg aaaacgatac ctgattacaa aaaaataact tttataagtt
      241 ctataacgtt gattatattt ttaattctta ttcttctcgt cgtcttggtt ccccgaattt
      301 ttggtttgac tccttatatt attgaggaca aagaaatgag tccatattat gcacaaggaa
      361 atctgatata tgtacgaccg aaaaatacaa atgagatttt agtcggagat attattacat
      421 attatgaaaa ttcaggaaaa aaaatctcga cgcgtcgcgt aatagccgtt gaaaacaacc
      481 acgaagattt ttatacaaaa gctgatacaa agacttatat tgagcctgga gtagtaaaaa
      541 agagaaatat tatcggtagt cccatctttc agattccata tattggacta gtcctttcaa
      601 aaacggcatt tgcatggatt caggggttat tctttacgat tgctttttgc ctaacaggaa
      661 tcacagcatg gaataccttt gtagagttga aaaagaagcg gagacgaaca cagaaatttt
      721 tgtaagaatg ttaaaaacat aaatgtattc cagagatcca acgactcttc tgaacatgaa
      781 acacgagaaa acactcatgc agcttgtaga tttagtcagt tgttcgtata atgtgtgaag
      841 aggaggagta gtatgcgcaa tgaaatgatg catcgtcctg tagtcaaaga agaactattg
      901 gattttatgc gtacccagca aaaaaaatta ccgggtgagc taggcaaact ggaagaagaa
      961 gctcatgtag cagaagtacc agttattccc catgaaacag ttgtattttt gaaattttta
     1021 cttggacagc ttcagcctga acgaatcttg gagatcggag cagctatcgg tttttcatca
     1081 agtgtcatgg ccacgacaat cggagaaaac gctcatgtta cgacaattga tcgtttcgat
     1141 gtcatgatcg agaaagctaa aaaaaactat gaacgtctag gactgacaga taaagtgact
     1201 ttgcttgaag gtcaagcagc agatatcttg ccggagttgt ctggtccgta tgactttatt
     1261 tttatggata gtgcaaaatc aaaatatatt gaatttttac ctgaatgctt acgtttgtta
     1321 agaaaaggtg gcgttttgat ggtagatgac atcttccaag gaggaacgat cttgctccca
     1381 gatgaagaga ttccccgtgg caaacgagct atccatcgta aattaaatga atttcttcgt
     1441 gttgtgatgg atcatcccga tttgacatcg acaatcttgc cattaggtga tggtgtgatc
     1501 ttaatgacaa aggaatcaga aacaatcgag ttgtgataca tgattatggc agcctgtaga
     1561 taatcgattg aatcgagggc tcaattcgaa cttgatgtaa aagtttctat atttgtaagt
     1621 caattaaagg atacaggaaa tctaaataaa caggagtagc atgaagtcaa tgtagctcct
     1681 gttttcaatt gataacctta gaacagctga aggagaatgt ctcgttttaa aagattgatt
     1741 tagtagttgg gccaaaataa ttcattattt gctaattaaa taactatttc gtattgacag
     1801 aagcaattta attatctata attattgatg ttccgctgat tcttgtcata gtagctcagc
     1861 tggatagagc atccgccttc taagcggacg gtcgggggtt cgaatccctc ctgtgacgct
     1921 aaaaaaccgt tagaaactga ggtttctaac ggtttttctt tgttttttgt gccaatattg
     1981 tttgttttca aaggcaaata aaataaaaaa acatccttat cgagtacaat tataaggagc
     2041 aaaaaaataa aactcatcag aaaagaggaa gaagatatga cgatactatc tagaatttta
     2101 gtgactctag ttgcaattga atttttttat atcatgtata tcgaaacggt gagaactgat
     2161 tctgacacga caagtagggt ttttaaaatg agtaaagaag agttaagcag aaaatctgtt
     2221 caaacattgt ttaagaacca aggagtgtac aatggactat taggagtggg actactttat
     2281 ggagcttatc tttcttccgc atctaaagaa atcacaagta tgctattaat atctattttt
     2341 tttgttgcat tatatggcag tttgactagc gatcgttgga ttttactcaa acaaggtggg
     2401 ctagctctgt tggcattgct ttctattttc ttataaatat agaaaaaata agaatttatc
     2461 taacaggaaa ctttgtgaaa aatattactt tatctcatga aatatgatat tctaatgaat
     2521 ggtattttag aaaatttcat gaaaaaggag ttagataggt gttcaaaaat tatgtttcct
     2581 cactaaaaaa agaattttca ggttatgatc tttcaagatt tcagaaagat cttttggctg
     2641 ggatcacagt agctgctgta gcattgcctt tagccttggc ttttggggta tcaagcggag
     2701 ctgatgcggc cgcaggtttg attacggcta tcattgccgg tatcgttatt ggcggtttat
     2761 caggcggttt ttatcaaata tcaggtccga caggtgcgat ggcagctatc ttgatgtcta
     2821 ttgcggcaac aaagggaatg caaggtgtat tgcttgctac ttttttagcg ggtctatttt
     2881 tacttgcagc aggacttttc cgattaggaa cactgacttc ttttatccca gcacccgtaa
     2941 ttacggggtt tacttcaggt attgctatca ttattgcatt aggtcagatc gataatttat
     3001 ttggtgttca ctcggaaggt acaaacgtta ttgaaaaact aagtagttat caaacgatag
     3061 gatttccgat aaacacagcc tctttgatca tgggagggct agtcatttta gggatgttta
     3121 tctatccaaa aaaatgggcg aaacgaatgc ctagttcgct gctggctatc attttggcaa
     3181 cagcagttat gctattgttc catttaccag tagcaactgt gggtaagatt ccacaaacat
     3241 tgatcagtag taatcgtttg aatatgggag attttagctt ttctgccttg caacaagtgg
     3301 cagttccagc tattagcatt gctttattag gaatgattga aagcttgcta tgtggtgctt
     3361 cggctggccg aatggcaaat aagcccttag atagcaatca agaattaatg gcgcaaggaa
     3421 ttggaaatct gttgcttcct ttctttggcg ggattcctgc tactgcggcc atcgcccgta
     3481 caagcgtggc catcaaatct ggtgcacaaa ctagattagc tggtatgata catgcagttg
     3541 tcttactgct ctccatgctt gtttttgcgc cagtgatgtc acagattcca atgccagcac
     3601 ttgcaggtgt tttgattgtg acggcttggc gtatgaatga atgggaaacg atcaaggagc
     3661 tatttactaa taaatattgg tcagcagttc tattgtttat ccttacgatg atttgtacag
     3721 ttatctttga tttaagtatt gctatcgtga tcggggtgat cggcggctgt gtattttttg
     3781 ttgtcaaaag cgctgctatc acgatttcat tagaaacgat cgattggcaa agaatggggc
     3841 tgccagaaac ggaaaagctg aataactgga cagtagtgta tattagtggt ccactgtttt
     3901 ttatgtcttc agaaaaactc aaaaataaat tggaagaact aaatcatcac gatggtgtca
     3961 ttttctccat gcgaggcgta ccaagtattg atttgacggc acgtgcagtt tttgatgaat
     4021 ttcaagaaaa agcagagcaa agaggacaaa cgattatcta tacttccttg cagccagaag
     4081 tagaaaaaca actttctcac ttgtgggaac atacattcac gcatcaacat caaacagttg
     4141 ctcatgcgtt gacagcttta catgcgaaat atactgcaat tagccattaa aacaatgaaa
     4201 aagaacagac aagactgtaa actgaagatt ttatggtctt gtctgttctt tttaatattg
     4261 ctgtaaaagt gaagctagta cttgccagtc ttgatggata acaggtacaa gggagcgatt
     4321 gtagaaaata gctgctggat gaaaaagtgg aagaattcga tagttttttt ctgaccattc
     4381 gtaggcatcc ttttgttctg ttaattgtaa gacaggccct gtatagagtt gaccatgatt
     4441 tttggtaacc gtatattctt tgccaagtaa acgttgaaga ccaatgtttc caagtgtcgc
     4501 aattaatttt ggctggacct tcatcagttc gtaatccaat attggtgcat gcgcaaatac
     4561 ttcggaacga gtaggtgtcc gatttggata aacagtttct gactgttgtg tccgtttatt
     4621 gatccgatga gtcacgcgat acgggcggct ccttacagca ctggtgatat acacctcttc
     4681 tcgtgttaag ccagttgaag aaagtgcctg catcaattct tttccagctt gaccgctaaa
     4741 aggaacatgc gtatcaatct ctgttttccc tggggcttct cccacgagca tcagtttagg
     4801 atgaagaggt ccttgcccag cgataaatcc ttctacagga cggccgttca ttcttaaaga
     4861 agcttcttgt atcagttctt ttgggtattc catttatgct cctccttttt cttttattat
     4921 aagaataaaa gaaacacaat gcgactattt tatttggtag aactgtgagg atagaaaagc
     4981 agaagtattg cttgaatttt tgttttactt tttgatttta aatttagttg actaacggtt
     5041 gctgttctgg taagctagta ctgttgtaat tgtggactcc acagctacaa ccgctcagaa
     5101 caagtaataa gcacagcata tgctgtcact tcggatggcg agtctaagta tatcagaagg
     5161 aggtgcttta tagcatgtac gcaattatta aaactggtgg taaacaagta aaagttgaag
     5221 tgggacaagc aatctatgtt gaaaaacttg acgttgaagc aggagaaaaa gttgtttttg
     5281 acgaagttat cttagtaggc ggagaatcta caaaagtagg cgctccaact gttgcaggtg
     5341 caactgttga aggtactgtt gaaaaacacg gcaaacaaaa gaaagtcgtt actttcaaat
     5401 acaaacctaa aaaacattca caccgtaaac aaggtcatcg tcaaccatat acaaaagtgg
     5461 ttatcgacgc gatcaacgct taatagcgtt tgagaaagaa ggcctatata tgatcaaagg
     5521 aacatttaag cgaaatgacg caggtcagat cgtttcattc actttgaccg ggcatgctga
     5581 tgctggtcct tatggaagtg atatcgtttg tgcgggtgtt tctgcgttag cgatcagcac
     5641 tgtcaacggg attgcctcat tagccggttt tgagccgatt gttgaaatga atgaagaaga
     5701 aggcggttat ctttataccg aagtcacttc aggaatgaca caagaacaaa acaatattgc
     5761 tgagattcta ttagaaaatc ttttattagg attacaatcg atagaagctg aaaactcaga
     5821 atatatccaa attaaaacaa ttaatgataa ataggaggtg cagaccatgt tgttatctat
     5881 gaatctacaa ttatttgccc acaaaaaagg tggcggttct acatctaacg gccgtgactc
     5941 agaatcaaaa cgtctaggtg ctaaacgtgc tgatggacaa acagttacag gtggatcaat
     6001 tctttaccgt caacgcggta caaaaatcta tccaggtgta aacgtgggta tcggtggaga
     6061 cgacacttta tttgcaaaag ttgatggcgt agtacgtttc gaacgtaaag gccgtaacaa
     6121 aaaacaagtg tctgtttatc cagtagctca agaagcttaa ttgaatctta tgattaaaga
     6181 ggttgtgaca agactttt
//
LOCUS       DAFKHN010000121         6173 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFKHN010000121 DAFKHN010000000
VERSION     DAFKHN010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.121"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            725..811
                     /locus_tag="LY912_002669"
     CDS             725..811
                     /locus_tag="LY912_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBM6956284.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="LY912_002670"
     CDS             complement(932..1621)
                     /locus_tag="LY912_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956285.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="LY912_002671"
     CDS             complement(1628..1906)
                     /locus_tag="LY912_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956286.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="LY912_002672"
     CDS             complement(1866..2780)
                     /locus_tag="LY912_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBM6956287.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="LY912_002673"
     CDS             complement(2762..3142)
                     /locus_tag="LY912_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBM6956288.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="LY912_002674"
     CDS             complement(3592..3879)
                     /locus_tag="LY912_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBM6956289.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="LY912_002675"
     CDS             complement(3899..4123)
                     /locus_tag="LY912_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBM6956290.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="LY912_002676"
     CDS             complement(4578..4748)
                     /locus_tag="LY912_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956291.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="LY912_002677"
     CDS             complement(4763..5296)
                     /locus_tag="LY912_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBM6956292.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="LY912_002678"
     CDS             complement(5317..6159)
                     /locus_tag="LY912_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBM6956293.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFKHN010000122         6021 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFKHN010000122 DAFKHN010000000
VERSION     DAFKHN010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.122"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            586..639
                     /locus_tag="LY912_002679"
                     /pseudo
     CDS             586..639
                     /locus_tag="LY912_002679"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            643..1242
                     /locus_tag="LY912_002680"
     CDS             643..1242
                     /locus_tag="LY912_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBM6956294.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            1258..1734
                     /locus_tag="LY912_002681"
     CDS             1258..1734
                     /locus_tag="LY912_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956295.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            1751..2653
                     /locus_tag="LY912_002682"
     CDS             1751..2653
                     /locus_tag="LY912_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956296.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIVIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            2726..2917
                     /locus_tag="LY912_002683"
     CDS             2726..2917
                     /locus_tag="LY912_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956297.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            3081..3668
                     /locus_tag="LY912_002684"
     CDS             3081..3668
                     /locus_tag="LY912_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956298.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            3668..4567
                     /locus_tag="LY912_002685"
     CDS             3668..4567
                     /locus_tag="LY912_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBM6956299.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            4567..5481
                     /locus_tag="LY912_002686"
     CDS             4567..5481
                     /locus_tag="LY912_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956300.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            5533..5748
                     /locus_tag="LY912_002687"
     CDS             5533..5748
                     /locus_tag="LY912_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956301.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
BASE COUNT         2306 a          769 c         1210 g         1736 t
ORIGIN      
        1 gaaccttggt cacaggcaga aattgataaa gcagtaaaat tgaaccgatt atcaaaattt
       61 aacgtattag gaaatgcctt ttaaaaatcg caatacacaa acagaaaaat accaaaaaat
      121 tagcaatgaa cgtaggtaag aacatgacaa taaataataa taaccctaaa aaatataatg
      181 ctcttgtcca atgctatatc gaaaacaaaa ttacaatgca agaagtcgct gatgaattag
      241 gcaaatcaaa gagcctagta tcacacgatt ttaagcacaa tgtttttccg aacccgattg
      301 agctgaggaa aaaatttcaa aagagagttt atcaagaaat aggtaagtgg attgatgaag
      361 ggaatgcaat tgacccttta attgaaaaat atcctttttt aaaaagcaaa aataaaattc
      421 aaaggttaat tcgtcaaggc gatattcaag ctaaagaacc tgttttgaca accaatgatt
      481 tggctaaaat aaatcttcat aaacaaatta ttgaagactt tgaaaaaaat ctttcaacaa
      541 ctgaaatttt aaaaaaatac aatattccga gaggaaagct aacatcgact ctttttagag
      601 aatatggaga atcggcagtt actaaagcaa aggaagtagc gaatgagaga aaaaaacaaa
      661 aatagtagtc gatacctagt agcgactgta gtttttgttt gtgtattgat tttcctgttt
      721 gattttttgc agattggaaa aagcataatt ggaaatacat tgagtgcaaa ggaaatggtt
      781 gctttaggtg gtttgtatga aggacacttg ttcccgaata tattcatttc tatcgtttct
      841 catattaact tgtaccattt aatttctaat ttattgttct tagtagttct tgaagaagca
      901 ctgaatgatc agtatgagtg gttaacatta ttgatcgttt taatcatatc aggatttcta
      961 ggaagcttag ttccttttct gctacacagc aacatcgtaa gtatggggct tagtggaggt
     1021 atttttggat ggattgcttt atttgcgatt gcatacatcc gttttgatag caagaaacat
     1081 ttattactaa gtgtttttgt attattgata atcggcattt tattggtatc tacttttgaa
     1141 tcaggcgagg caaatgtctt gtcacatgta atcggatttg tctgtggaat gatcttggga
     1201 tttattctaa agaacgtttc attgatcaaa caaaagaatt aaaagggagt gctaaaaatg
     1261 ccaaaaagaa aagaaaagaa aattccagtg tttttgtctg tctcagaaat gttatcactt
     1321 caaatactgt taagaaaaaa gattgaaaca atagacgaag aagttagaaa taaaagggct
     1381 atgtacgaac aacgtgaagc gctaagagaa cgaatccact attttgatga tatacacact
     1441 aaaatctatg aagcacgtac aaatcacgaa gacgaaagta aattaggatt agctcaacaa
     1501 cggatacttg aatggcttaa tacgaatact gatcaagaac cgttaagagt gattagtaat
     1561 ctttttgaat ttggaacgaa gcattggttt aatgctgtag agaaggatgc tgacttacaa
     1621 gaagcgtttg atacgctaag taaggatagc aaatccatgc gagatttatt gattacttat
     1681 ctaaatgagc atgagtttga acaaacgaaa accaaaaaga aaaataaaga atagaaagtt
     1741 gtgatgaatc atgctattaa ccctgttagg ttatttatgt ttaattcttg ctttttttgg
     1801 ggcaatcgct ataattattg gtcaatttca aacaaataat ccgattatgc gtaacatagg
     1861 cattgtaatt gtgattgtaa cctttattgt gtttaatgcc actaagattt ttggaagtaa
     1921 cgataaacaa tttggtatat cgggagttaa taatagttat gctccagatt ctttgggaag
     1981 ggtagtaata gatggaacat ttgaaaatgt aacgagttat aaaaatgttt cgctgacagt
     2041 gaaggaagat ggcaagaaag catcagacga cgttctcgct actattaagc cgtctcaatc
     2101 acaatttgaa gtgttttata cagttaaaga gaatagccct gtacacaagc tgacattggt
     2161 ttttaacgtt gatggagaag aatactataa agatgtaaaa ataaataaaa catcaacgaa
     2221 aaagattatc gaatcagcga aaaaagaagt agctacagaa gaaagtacaa ctgaatcaag
     2281 ttctactgtc gaagcggaac taccagataa aattgatttt gatcctgaaa aagtcaaatc
     2341 gtttgaatct gtttctggtt ctatggctga tcggtttaac actgaagtct tcaaagctat
     2401 caaaactgtt aaattggata ctgaaaagca aatgattaat gttaccttat tcaattcagt
     2461 tgaatctatg gatcaggata aaaaagttac ggttgcaaga gaactaggaa aaagagtaat
     2521 tggtttgtat cgtggtactg ctaaaccaga ttcagacggt gcagatttgc cagttcatgt
     2581 agtttatgaa gacggtaaag tttttggaga ttctacagca aacgaagcat taacgattaa
     2641 attggctaaa tagccagaaa gttataataa acaaatggtg tcacaccaat aatatatagg
     2701 tgtgacacct tggagatgat agctgatggt agtaaataaa gaaaaagtta gaaagtatgt
     2761 gactttaaaa atagcttctg ttaaatattt agaaaagcga gctaaagaag aagaaagagc
     2821 aagaggtaag aaagtaacag tttcagagtt gttagaagaa ttgatcgaga atgatcaaac
     2881 aataagacgt gcatttacta ataggtctat cagataacaa tataattaat aaaaaagaaa
     2941 gagtgatttg gtcttagact aaatcactct ttttatataa agtttcttta cactcattcc
     3001 gaataatgtt aaaattcttt atatgatata tagttccttg tcagaggaag agataaccag
     3061 caatattgga gggataataa gtggaaaaca ataatgatat tagacatttt agcattgggg
     3121 aaagagttac aacagtaagc gaattatcaa aggattatag agataaagag ggaacgatta
     3181 tttctcttaa taagaatcga agaggcgttt ggcaatatgt tgttgattta ggtgatggcg
     3241 ttacagttga gtgtaaagat agtcaactga tcagaaataa tggcagtcat tccattgaaa
     3301 aagcaattct tgtataccca aaagtatcaa gtaagatcat gaatgactgg ttgcttggaa
     3361 aatttggtga gtacaataaa aaagaaatcg cagaagtgat cggcaaatct tatccaacag
     3421 tattagggta tctaaaaaag ataacgagta aagaagcaaa aattgaggat gttttaacag
     3481 taagagagct tcaatcatta atcgagtatc ggaataaaca aataacaaat cctgagtacc
     3541 ttagaaaaga agatggtcta ttgaaacaat tggaacaagt aaataaaatc cggaagatgc
     3601 aaaaggtagc tcctttaagc cttgatacct ttaaaaaaat ctatttgaaa gagatcaaaa
     3661 aagactaatg tggactgtaa ctttaccgtt ccaacctgta tctgcaccaa gaccaagtgc
     3721 aagaaggaat gctgctgatg aaactaatga cgtagcagag aaaaggattt caacctacta
     3781 tgataaaaag tatcttgatt atttgaaaaa aataaagagc tttatcgaag atcaagattt
     3841 attagatgat gaattttact cgattgtaaa tgatcctatg ggcgcaatta tggaagtgga
     3901 cttttactac cagataccaa aaagctataa aaaagtctat aacattatga agacaacagc
     3961 gccagattta gataatttag taaaaagtgc tatggatggt atttttaaca tctcagctat
     4021 acgagatagc catatcacag gcttaattgc ttttaaatat aatgtggcga acgaaggaaa
     4081 aacagttgtg aggatcaaac gatattcaga atttgagtgg gatacttctg aaggattgaa
     4141 cggagatata tgggaagcta catttgattt taaaccagta gcaacgccaa gaccaaagtc
     4201 taaatttaga ggaaatggga ttatcactta ctatccaaaa gagtacaacg actatttgga
     4261 aaatatcaag aatacgctta aagagaaaga tttggtaaat gatcaactga aaaaggtaat
     4321 gaatgctcct atgggggtta tagctcagat agattatttt taccaagtga gaaaagataa
     4381 gaaaaagctt gattcactga tgcgtacttc acagccggat attgataatt tagtcaaagg
     4441 aacattggac ggaattttta acaaggaaat aggcatcaaa gatagcaggg ttgtagggtt
     4501 aattgctttt aaatacaata cttttgaaaa gtcgaaaaca aacgtgagac tacaggagat
     4561 gggctgatga ataataatga aaaaattctt catgtacttg atagctttga aataattcaa
     4621 gaagaactaa aaaaatatcg ggatgttttg gaacaaagat atgattttgt caatcagcaa
     4681 aagagtaatc acatggattt cattctcaat atgaatgact tgaagaagaa attagttgaa
     4741 cgaaaagaac aagaaaagtt gatcaaagct tactttgaac tcggtgaaaa agaagttaaa
     4801 aatgcaatgg aactgaatga agagcgcagg gttttagatc agctgttaga acaattattg
     4861 gtgatgtttc aaaaaggacg aatagatgag gatttaattg aagaaggatt gagaaaatat
     4921 ccttcaaact caggtatcgg aatagtgctg aaagcgattg atgaagaaga aattgaagct
     4981 ttcataccgc cagaggattt tgaatcggca atggaatata taaaatatta tagccaaggg
     5041 atcactgctt ttagagagtt tgatcctgaa gatgttattc atgacttgaa caacctaaaa
     5101 gaatggtgtg aaagttatgg agtcgatgat tccggattgg actacttgat cagtattatg
     5161 gaaatcgaag aagagatgcc ggataagcct gatccaacag atattttaga attgatccat
     5221 gaagctagaa atccaattgc ctatatttct agaggatata ctgtattgga atactataag
     5281 ccttatatat cagcgatgaa ccatttaaga cgtgtattaa gggaaaaacg tgaataccgc
     5341 tcagtgttga atgcaacgaa tagattagaa aaagctgttt cagagctaga tgcttattat
     5401 cgtgaacatt acctgcaagc aggtggtatg ccaagaaata cgaaagcaaa tatcagtagg
     5461 tatataaaaa aagctgagta ggcggagtta gcccataaaa tggcaaaagg taacctgaaa
     5521 ggggcatttt gaatgaaaag ggatgttttt gaattgtacg tattagaacg tctagaagac
     5581 ggcatgatgg cacaagagat aattgatgaa attgatgata tgatcagcag atttggtcaa
     5641 ttggagttga atgatggaaa caaaaattcg gtagtgctaa aacaattttg gttgaacaat
     5701 ttttcgtata aggattttat caaagaaaag gcaaatacat tgtactgact aaattcacga
     5761 ggagcagtga tgagagctta ttgctaagag cagttaggct cttttttgtt tgtgtaaaat
     5821 tatttgtttt ataatacaca tttatacaca aaaaatattg acagatagta cacaaatgtg
     5881 gtaggatata tttgtaagca agttagatta acaagttaaa ggaagagcag ttatgaaaaa
     5941 agaagaacta atagatatat ttcaaattgt tgaacgagca aataatatgg gaattatgtt
     6001 ttttgatcgt atttctttaa a
//
LOCUS       DAFKHN010000123         5871 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFKHN010000123 DAFKHN010000000
VERSION     DAFKHN010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.123"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            690..1658
                     /locus_tag="LY912_002688"
     CDS             690..1658
                     /locus_tag="LY912_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6956302.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="LY912_002689"
     CDS             1669..2484
                     /locus_tag="LY912_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HBM6956303.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="LY912_002690"
     CDS             2552..3262
                     /locus_tag="LY912_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6956304.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..4539
                     /locus_tag="LY912_002691"
     CDS             3298..4539
                     /locus_tag="LY912_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBM6956305.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKNESSPQSCVKVQPHQKH
                     NVLRCEPNCHAFLSEERGQEQ"
     gene            complement(4597..5784)
                     /locus_tag="LY912_002692"
     CDS             complement(4597..5784)
                     /locus_tag="LY912_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBM6956306.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT         1910 a          975 c         1175 g         1811 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaatgagtc aagtccacaa
     4441 tcttgtgtaa aagttcaacc tcatcaaaag cacaatgttt tgcgttgtga acctaactgc
     4501 catgcctttc tttctgagga gagaggtcag gagcagtagc gcagcgactc ttgatgtctc
     4561 tcctcagaaa gaagagactc gcacaggttc atggtgctaa atgttattcg aattaaattc
     4621 taaatatttt cgtggagaag ccagccactc agtgtctttt tccatcaaaa gtgttccaat
     4681 tatccgagtg atggaattga tatttggaaa aatccgaatc actcgttctc tccggcgaat
     4741 ctcttcgttc aaccgttcca acacattggt tgtacgaatc cttcggcgga tattttcagg
     4801 aaaagacaaa atttgaatag catcttcaaa gccgttttct aaaatgtcgc aagcagcact
     4861 taattttgaa tcacaaccat atttttccaa gaagtgctct tttctttcac gtgtcaattc
     4921 aagttcagag gctttaaaga tactcttcaa ctcgtctttt acatcagaag aaactttctt
     4981 tggcagctta tcaaaaatat ttctcaaaaa gtgggcttgg catctttgcc agctcgcacc
     5041 taaaaagttc ttgcgaacag ccttaactaa ccctttgtgt gcatcagaaa tgaccagttt
     5101 tacaccgaac aaacctcgtt gaacgaacga ttgaaaaacg gtatcccaat tatcttccga
     5161 ttcgccgtct tgaacatcaa aaccaagaat cgtacgtcgt ccatcagaat caatgccgat
     5221 accaatatat acaccttttg agacaatacg atgattttcc cttactttca tatacagggc
     5281 atcacacatg aaaaatggat attccgagcc ttctaggctc cggtttctcc actcaaaaac
     5341 aaatggatcc aactgtttca tcagatttga aacgaatgat ttagaaacag tcgcaccatc
     5401 cgttagcagt tcaactgttt tagttacttt gcgagtggag acaccagaaa tgaccatttc
     5461 aatcatggca gcgatcaaag ctttttcgct tcgctgatat ctttcaaaga tagtaggact
     5521 aaacttaccg tctctggttc gtggaacatg aagttctaac gtaccaattc gagttgtaaa
     5581 cgaacgatcg tagtaaccat ttctttgtga ttgccgttct tctgaacgtt cataggcatt
     5641 tgcctgaata tattgatttc gttgttcttc catcagctga ttaaacatga tagtcataag
     5701 tgtttttgcg gtatcattcg caccgctttc gtttataatt gcttgaattt cttcgctttc
     5761 aaaagtaaaa tgtacttgag tcattgatat cagtcctatt cgagtatgtt ttctgcaaaa
     5821 aacattgtac tcctaactga gatcaatggc ttttttgatg cttcactttt a
//
LOCUS       DAFKHN010000124         5829 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFKHN010000124 DAFKHN010000000
VERSION     DAFKHN010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.124"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..573)
                     /locus_tag="LY912_002693"
     CDS             complement(<1..573)
                     /locus_tag="LY912_002693"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBM6956307.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVE"
     gene            complement(657..2084)
                     /gene="uxaC"
                     /locus_tag="LY912_002694"
     CDS             complement(657..2084)
                     /gene="uxaC"
                     /locus_tag="LY912_002694"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBM6956308.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(2158..3237)
                     /gene="uxuA"
                     /locus_tag="LY912_002695"
     CDS             complement(2158..3237)
                     /gene="uxuA"
                     /locus_tag="LY912_002695"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBM6956309.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(3240..4871)
                     /locus_tag="LY912_002696"
     CDS             complement(3240..4871)
                     /locus_tag="LY912_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBM6956310.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            5181..>5829
                     /locus_tag="LY912_002697"
     CDS             5181..>5829
                     /locus_tag="LY912_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6956311.1"
                     /translation="MKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRTPI
                     REALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQKK
                     RILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERFRW
                     LRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK"
BASE COUNT         1858 a         1176 c          820 g         1975 t
ORIGIN      
        1 ttcaacagaa gccaataaat tcccacctac accaactgca acaactccta cttcaaacca
       61 atcttctaag ttctctatac ttactccgcc agtaggcatt atatttacgt gtggtaatgg
      121 agcttgatag gcttttacaa tggatggacc aaaagcagaa cctgggaata gtttaatgat
      181 atctacgcca gcagtaagtg cctcctttat ctcagtaatt gtcatacaac ctggtaaata
      241 aggaatttga tataaattac aaatctcagc tgtttgtcga tcaaaagatg gactaacgat
      301 atattctgcc ccagccataa ttgcgatacg agcagtaaac gcatctaaaa ccgtaccggc
      361 tccgattatt acatcttttt gatcagcata ttttttagca atttctttga ttatttcttc
      421 agcattagga actgtaaaag ttagttcaat ccctttaatt ccacccgcaa taattgaatt
      481 tattgcttta atggcctcat ccttattttt cccacgtaca accgcaatga ctccagccgc
      541 ttctaactta cttaaaattt ctactttttt catatctatc tccttccttt atggatacat
      601 actttgtcta gctgtactaa cttacaaaga ataaatttaa gcttttattt caagtattat
      661 tttctacttc cgatttcaaa aaaattaaaa taattatacg cattacgata acaaatattc
      721 tccactatct gactaagata catttcatca tctggaattc ggcctgcttt aacccactcg
      781 cttagtaatt gacataatac tcgacgaaaa tactcatggc gaggatagct tagaaaactt
      841 cgagaatcag tcaacatacc tgtaaaattc gacaacaaac tttgttgtgc catcgtagtc
      901 aactgttgac gcattccttc agctgtatca ttgaaccacc aagcacatcc caattggatt
      961 ttttgaatca tacccccttg gaagctttgc attgctgttg ctagtggaag ccaatcagtt
     1021 ggatttaatg aatataaaat tgtttttggt aagcacccac tcttttcagc ggtatcgaac
     1081 aatgctacaa cattttgtgt caaactagct tgatccccca tcgaatcacc accgacatct
     1141 actccaattt gttcctttaa tatacttgaa ttatttctta aagcatttaa atgcatttgc
     1201 atcgtccaac catatcttgt atactcagac atcaaatgta attgaatacc tgtaacaaat
     1261 tgtgcaattt ctgataaatg gaaatccgtt tttcctgcta aagcttttat taacagattg
     1321 tcgagtattt tttcatctgc tatttcataa aaataagtat tcaaaccgtg atctgctaat
     1381 cgacagccaa tttgatgaaa atgatccact cgttggctca atgcttgctt caacccatta
     1441 aagtctttga ttggtatagc cgctgtttga ctaagtttta aaatatagtt cgaaaagcct
     1501 gatgatttga tactccagac cttatctgga cggaaagtag gtaatacctt gaaagaatta
     1561 tcctgtttag aaagctcagt atgataccac aagtcatctg taggatcatc cgttgtacag
     1621 atggctttca catccatcat ctccaacaat tctttcgggc gataggaatc cgtttgaatt
     1681 ttttcgttag cacgtcgcca aatttctggt gcattcttct cagaaattgt caaatcaata
     1741 tcaaagtaac gttgtaattc caaatgagac cattcaaaaa taggattacc tggcgccttc
     1801 tccactgttt ttacaaaagc taaaaatttt tcataatcat cacctggacc actgatcaac
     1861 tcttcttcta taccattagc tcgcatcaat cgccatttat aatgatctcc agctccttta
     1921 tcatttaacc atacctgagt caaattcttg tattgcttat tttctagcaa atatgctggg
     1981 tctaaatgac aatgatagtc gataattggt tggtgttttg caaatttatg aaaaagtctt
     2041 ttagctattt cattctctaa taaaaagttc ttatctaaaa acatatttaa acactccttt
     2101 ccttccgtta gtttttagaa gagaaaattt ttcctctaaa taaactccct tatataatta
     2161 tttactcgcc cccttttcaa gcgcttccca aataccattt aaataaactg cacctagagc
     2221 tcggtcatat aatccataac caggtctacc ggtttctccc caaatcatcc gaccatgatc
     2281 tggacgaata tagccattaa atccattatc gtacattgtt tttaatatct tatacatatc
     2341 tagagaacca tattctgatt tatgcggcgc ttcgtaaaaa tcgagtccat tgtcacttaa
     2401 atatttgata ttacgaacat gtgcaaaagg aatccgatcc cgttgacaaa attcagatag
     2461 aatttcatag acatcattat ctggtcgttc tgcaatactt ccagtacata atgtaatacc
     2521 attagaagga gaatccacta cattacacaa ccaatctaaa tcgtcacgat ttttaacaat
     2581 acgaggtaat ccgaaaatgg aatatggtgg atcatctggg tgaactgcca ttttaatccc
     2641 aacttcttca catgtcggga taattgcttt gagaaaatat gcaaagttct ctcgtaattt
     2701 ctcttcatca acttctttat aggcttctaa taattgctta atttgtgata accgatgagg
     2761 ttcccaaccc ggcaattcaa aattattagt agaattttct acttctctaa taatttcctc
     2821 cggatcagta gggatatttt ttgaaatata ggctaacgta gaagacccat catctaaacg
     2881 ataatccaaa tccgatttta cccaatcaaa tactggcata aaattataac agataacctc
     2941 aatcccaaat tctgccaaat tgcgaatcgt ctgtttataa ttctcaatgt attgatctcg
     3001 tgttggtaaa ccaattttga tatcatcatg aacattaaca ctctcaataa ctttcaaggt
     3061 aagtccattg gcttcgactt catcttttaa agatttaatt cgttctctcg gccaaacctc
     3121 tccggctggt atatccatta atgttccaac aattcctttc attgctggga tctgacgaat
     3181 ttcttgtagt gagatttttt cttcatttgc cccataccat ctaaaagtca tttccatagt
     3241 tactttcctc caacttctgt tatatattta ttgattgttt tacgaactgc ttgaggacct
     3301 actagcattt cgcaaaagat tttttcagtt ttctttccta ccccaacttg atataaatct
     3361 aaaccaaaga tttctttatt ttctaaaatt tcctgtaccg cacaatgaat ctttgaagga
     3421 tcttgttcac ctaatttcaa tactgataat ttatcctgca actctaccaa taacggatca
     3481 ggacttggca caaaattttc cccttgatca tcgactgcca gtaaataacg taaccaagca
     3541 gcaatagcga taggaataaa tgttagattt tctgcatttc cgtctttttc gacatacttt
     3601 ttaattgttt caccatagcg aatcgctact ttttgagaag tatctgttgc aattcgttgt
     3661 ggtgtatctg gaatataggg attaggcaaa cgtttattaa ttacttcatc aataaattgt
     3721 tttggatcaa taatgcctgg attttcaact actggtaaac cttctaaata acctattcct
     3781 ttgattaaac caaccaaatc atcatcctgc atctctgctg aaattgattg atatcctagc
     3841 agacaacctg ttactgccaa agcagtatga agtggattca agcttgtcgt aaccttcatg
     3901 atgtctgctt tatcaaccgt ctctctatct gtcataatca caccagcctt ttccaattta
     3961 ggccggccat ttggaaaact atcttcaata actaaataat gaactacctc agtattagtg
     4021 aaagcagcaa tattggtatg tttttttgtg tgaatgatat ctaaatcctc gagccccatc
     4081 atcaatagat cttcctttac attctctgaa ggatttggcg taattcgatc aatcatactc
     4141 caaggaaaag tcactttttc tttatccttt aaataagcaa taaatttttc agaaacatat
     4201 ccttcttttt gccaagcttc tgcaatcgta aaaatactat cttgaaaacg ttgaccattc
     4261 tgtgagaaat tatcagtaga aaccatcgca atcggcaact ctccagcatt aaatctgcta
     4321 tataacaagg atgttacaat actcatcgta tgttgaggat tgctaggtcc agatttgata
     4381 tcagctttga ctaccgaaaa gaattgccct ttagaatctt ttaaactgta acctttttca
     4441 gtaatagtaa acgttgtaaa ctgtaattta ggatcttcaa aatatttaac cactctttga
     4501 tagtccgcta tattcttcgg attgcaatat aaactatcag ccgttactgc caaaagtctt
     4561 tttttgagtt caccatctcc actcataaca atttccaaaa tgtcattgtt atagtcatga
     4621 taagcttttt ccactacttc ttcatcaaat gtttcacaca caactactcc tgtttctaat
     4681 tcattttgat ctgctaagca ttgagcaatt tctgcatgaa atcctcgata aagatttcct
     4741 ccaccaaaat gaagccatac tggatgttgc tggccttctt gcttaacttc tttgacatca
     4801 aaacacggca gtagaatctg catttcattg aattcttcga tagaattttg ccaattttta
     4861 atcgaaacca taattaacct cctcaaactg atatgttagt tttgatacat tttatatttt
     4921 aaaacccatt gtaaccgttg tcaatataaa aagggaataa acttgctttt ttctaccata
     4981 tcagaatgat tgtatttttt attcagaaaa ataaaatact ccttcttttt ggactgattt
     5041 tatcgaaact tattttttct ttttttcatg tattctttta tttttataac tagtgtatta
     5101 cttcaaaatt tgatattata tggcatgaac agaattaaaa tatcagttaa aataaaagtt
     5161 aaggagcatt gtgtatgaca attaaaacta gtctccaaaa tcaagcttac caatctattc
     5221 gccgacaaat tatctatgct gacttagaac ctggaaaaaa agtatcagaa aaaaaattag
     5281 aagaaacact ttctattggt cgtacaccaa tacgtgaagc actgattcaa ctccgacaac
     5341 aaggtcttgt tgatacaatt cctcaaagcg gaaattatat ctcattaatt gatttagatt
     5401 cggccaaaaa tgctcgattt gtcagagaac atttggaacg acaaattatg ttagagtgtt
     5461 gtgccaaaat gaataaccaa aaaaaacgga ttttagaaac tataatttca gaacaagaaa
     5521 aagctgttag tcaaaaaaat gctcgtagtt tttttcataa tgataattta ttccataaag
     5581 cttgttttga aattgcagag cgagaagaag tatggcaatg gttagaaaat aacaatacac
     5641 acttagaacg atttcgatgg ctacgagtaa aaacggaagg attaaagtgg gaaaaaatta
     5701 tggaacaaca ttatcaacta tttgaggcat taacaaaaca agatccagaa gaagctaact
     5761 ttctaacatc gttgcatctt catttaatgc ttaatgagca aaatattgtt ttagctactc
     5821 atccaaaat
//
LOCUS       DAFKHN010000125         5802 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFKHN010000125 DAFKHN010000000
VERSION     DAFKHN010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.125"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(906..1079)
                     /locus_tag="LY912_002698"
     CDS             complement(906..1079)
                     /locus_tag="LY912_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956312.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1082..1480)
                     /locus_tag="LY912_002699"
     CDS             complement(1082..1480)
                     /locus_tag="LY912_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956313.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1696..2751
                     /locus_tag="LY912_002700"
     CDS             1696..2751
                     /locus_tag="LY912_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBM6956314.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2771..3124
                     /locus_tag="LY912_002701"
     CDS             2771..3124
                     /locus_tag="LY912_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956315.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3306..3602)
                     /locus_tag="LY912_002702"
     CDS             complement(3306..3602)
                     /locus_tag="LY912_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956316.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3606..4424)
                     /locus_tag="LY912_002703"
     CDS             complement(3606..4424)
                     /locus_tag="LY912_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBM6956317.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAVNENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWMVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4650..4871
                     /locus_tag="LY912_002704"
     CDS             4650..4871
                     /locus_tag="LY912_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HBM6956318.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            4873..5139
                     /locus_tag="LY912_002705"
     CDS             4873..5139
                     /locus_tag="LY912_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBM6956319.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5252..5791
                     /locus_tag="LY912_002706"
     CDS             5252..5791
                     /locus_tag="LY912_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956320.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVGTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKLQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVT"
BASE COUNT         2038 a          966 c          864 g         1934 t
ORIGIN      
        1 gctccatgtt attttatatt tcctttttca tgttattttt atccagaaac cgatcaagtt
       61 tttacctatt cccaaaatcc atttattcgt tatttttttc actgattaag aataattatt
      121 tgatgcttaa attagctaaa aaagcgattt gttactgata taatcatgat attgcagctg
      181 aattaggcgg aaagataaaa tgttcgcaaa atcaaagtat caattatctt gtttttttat
      241 aaatttgtaa gtaaaaatct aaaaaagttt tcttttaatt ggtatatgta ttaaaatcac
      301 atttaatcac ccataaagta tgcgctttca tttttttgga tgagattaat atcaataaat
      361 aacgatgtaa aaatcattta ttatgctctt ttataaggat attaattgat ctaatttgaa
      421 aaaaaatcaa aatttaaatg ttttaatatt acaaataaaa tcatgttatt gtaaaatggt
      481 ataaaaaagc taaatattct atttttgtta ttttattagc aggaaaattt aaatagtttt
      541 acaagaatcc gtagaaatat attggttttg ccttcagatt aatactggat catattaatc
      601 tgaatataat atatgaacta ataaatagct taacctcgct attttgtttt ttctgatcac
      661 tatctataca gcattagtaa atagaatttt aaaaataaaa aaattaagac aaaaaagtat
      721 caacataaac atatacatat acacgtttat gttgattcac ttaatttgtc ctttaaaaag
      781 cacttatttt aatataatgt tattttataa tcttattaca agctgattgt taggcgttgt
      841 cctttcatta catttattaa cggttatttt attgtttaat ttattaatta tttttgatct
      901 aaaacttagc ttaacaaata aataattaac caaccgccag ataaaaatgc gatcattgct
      961 aatacataag caaagataaa aatatgttcg atcagcttaa accctgatgc gattaagcag
     1021 accaagtaaa atagaaattc tcttacagat aatggtaatt ttctaactag catactcata
     1081 attaacaccc caaagtaata ttgtattttg aacattttac atccaataca gcatcaatca
     1141 accattgcca atcaaaaata caaggcttca ttgaagtatg tttttcagat gaaaagatat
     1201 aatataattt cttcggaata atattttcag ttgttgggat caagctaaat ctaataccgt
     1261 ctaactcata gctaccagct ttctctccat taaaaatttc cttagcactt tcttctaaag
     1321 aatcaaaata tttttcgaca gcaatctttg aagcttttac tattgaagca tttccctttt
     1381 cgataaaatc tgcttttgtt ttaccgacaa taagtaattc ttgatcagta aaatcttcta
     1441 aaataatggt agtgtaattc ttatttcttc tcaatcgcat caggatcact ccttaatata
     1501 atttatgttt ttataatatc ataataagat aaatttgcaa gcatttattt acaccttttt
     1561 atttacactt tattataatt aattagactt ttatgattgc atttttttct tataaacagt
     1621 tgcaactaat agtaaatagg tgtaaactat tttcgtaccg aaataccata aacacaaaca
     1681 gaaagaggtc ataccatgaa agaaccatta ttgttttccg ttgacttagg gaataaatca
     1741 gtaaaagaaa tgagtacaca cgtttctcca ctctcacttc cctctcgtat tttgaacaaa
     1801 aatatcatta attcaggacg tttttctaat ataggttcct cattaaaacg atcactaaac
     1861 gtttctgaat atagcctagt aaacactact gaaagctatt actttgggaa ggatatacac
     1921 gagctaggaa aagatgacta cgtgatagaa tcactaggtt ttgggatcag cagatacaag
     1981 caggaaacct accaaaatat cctatctttc tctttagcta acctagcacg tttagaagat
     2041 caatctgatg acgttttaac cgctaatcta gttttaggtc tgccttcatc cgactatacc
     2101 gaaacaatcg tcaaatacgt gatgcaacaa gccacacgac aacattcagt tgaagttgac
     2161 ggtaaagctt ataatataaa cgtagatacc gtttgggtac tgccacagcc gattggaaca
     2221 ctatataacc tcctacttgc tgatgatggt agtgtacaag atgaaacatt gatcagtcag
     2281 aagatcggtt ttgttgatat tggcggtggc acgaaacttt ttgatgttgt ccaaaatttt
     2341 gaaattgacg aaaacaatcg tgaacaaaag gataccggca tttttacttt atataatcgt
     2401 atcgtaaata tgcttgacct tccgatcagt cctaatgctt tccaacttga aaagattatc
     2461 cgagaaggca aagaaaaagg cgtatatcta tttaagccaa gcggaaatga aagttttgat
     2521 atttcagaag tagttgaaag agaaataaaa acatacacca atatggttgt tgcagaagtt
     2581 ttagctacat tcaaaaactt cacaacctta gataaagttg tctttactgg tggtggagct
     2641 tctattatcg acaaacaact tgtaaaagat aaaattccgc ataccttgtt tgttgaagac
     2701 agtgaatttt ctaatgtaaa aggcttttac aagtttggtt taactcaata aaacagcgaa
     2761 ggagatcaac atgaataagg gaaaatcaga gcgttatgta gttataatca atagagaaaa
     2821 ggttagcgag ttacctttag cagagtttct tgaatccgaa tatgaaacac taggcgttaa
     2881 atactctcag acgatcaaaa aagctttgaa cctatatcgg cgtgtaaaga acaatgaagt
     2941 tacaattatt gaagcaggca acgatagaaa cgatagcaaa gtagcagaag taaagaataa
     3001 accaactgat cataacccta ttcaacaaga gcatccttca acggttacat ccgatcattc
     3061 agcaaagaaa gaaaagccaa tgctgaaagg gttcaatgca ccaagtaaca aagacttact
     3121 ttaaaaataa aaaggcgagg ttacaatacc tagccttttt attatgtaca aatataaaca
     3181 taaacatata cgtatacatg tatataaaca tgtatacgta tatatccata aacacgtata
     3241 ttaaatttag ttaagctata cctaaccgct tattccaata aaaaaagtga tcagctttaa
     3301 actgatcact caccaaaaac ttcatcatac aagttatcta tcatttcacc aagtaaagct
     3361 gaatctgatc gaattcctaa cttttcgctg attttagata gtttctttct ttgcgatggt
     3421 tgaagcgtga attgataatt tttcttcttt tcagaactat cactttttag tttagctacc
     3481 aaagaacttg ttgtttcttt aggtgtttgt ttaggttctt caactgcttc aaccacttca
     3541 ggaacttctt ctacttcagc ttcagcgaat tttttaaatc tattttcttt cacttcaatc
     3601 actccttatt cttgtgccgt atcaattatt ttgttgtata gcgtaaacgt gctttcaaag
     3661 aaatccttat tcttacgata gatattctta tccttagcga actcagcaat attcttacct
     3721 tctaagctag ttgcattaag caattccttc tcttgtacat atccaagata attagataac
     3781 gttggtacca gttctaggaa ctcacgactt gaattagtat tatgtttgat cctgctaccg
     3841 atcgtagcgt atttagtttc catcagtgtt tcaccagtct taatatcaat caactgtttt
     3901 gctagtgcat caatatcttt accaagcttc agcaaagctt caaaaccatc tttagatgga
     3961 tcagaaatgc ctacgacaag atcagataca gcccaagcat tttgagctag tagacctgca
     4021 tcattatgag tatcaatcag aattagatca tacttctctt taagctgttc atagttaaca
     4081 accatccatc taaacagtag ggttctgttg ttaggcatat cacgcatttg catctcaact
     4141 tgttttaaat cttcacctgc tactaaaata tccatgttct catttacagc taaaggttca
     4201 gctgatccat gaagatataa atgattgatt gtattctctc ttttcgcttt actgaaagca
     4261 tcaggaaatc gttttgatag gttttgcgac ttatcttcat caatatacag caccttcata
     4321 cctaaatttt cgacagcata tccacctaga ttgtagattg ttgttgtttt acctgttcca
     4381 cctttttcaa tgtttccagt aatgattgac aacttctttt ccatgattaa acctccctta
     4441 ttaacctttt gtaactccat tatacactat aaacacgttt atgtatatgt ttatatacat
     4501 aaacgtgttt atatttatat ttgcttttat attctacaac ataaacatat atatgtatat
     4561 gtttatgttt atgtatatat tcatatatat aactattgca tttgtcatac aatcgtagta
     4621 caatgtaatt gaaaaggagt tgataaacta tgccagtaat aagtattcgt gtatctaaag
     4681 aagaaaaaga ttttcttgaa aaagttgctg aattcaacgg agataacatt tctgaattta
     4741 tgcgtagtaa ttccctgcaa acagcagaaa cgttagtaga ctttgccacc tacaagcaac
     4801 taatgaaaga gcatgaggaa aacgatcaaa gtatttccca cgaagatatg ctaaaagagt
     4861 taggcttata agatgactta ccaagtaaga tatgaacgtg aagctcaaaa agcgctaaaa
     4921 aaaatggata agtttcaggc aaaggttatc ctaaactgga tcgagaaaaa tcttgtaggc
     4981 actgatgatc caagaaagca tggtaaaggt ctaacagcta ataaatcagg ctactggcga
     5041 tatagggtag gtgcataccg tataatagct gatattagcg agcatgaagt gacaattctt
     5101 atattgtcta ttggtcacag aagtgaagtt tataagtaac agacaagctg ataaggcttg
     5161 tctgtttttt tgttaaccca acaaaatcac tgtttacgat cccactttac ctaaaaaaga
     5221 acaatatcct cttgatatta tacacaccag tgtgtataat ataagtgtaa acaagctaat
     5281 taactttcaa aaggagcgat tttttatggg atggtatggt gattattcat cagcaaatga
     5341 agtgatcgaa gaaaagaaag ggtacgccaa aaatggtttg gaaatcgtag gtaccaaagt
     5401 aacgaagacc tatggaatta tccttttcaa agatgcagaa ggaacctacg atattgacag
     5461 cttcatcttt cgagatgaaa tgtacaaacc aatctacttc ttaaatgaca gtcctgctta
     5521 ctttaagaaa attccgaaaa aatggttgaa attctttgtc ggtgatcaag aaaaaatggt
     5581 taagctacaa ctagatagaa ttaaagaaga aagcaataaa ccaaaacttg atgacttatt
     5641 agttgcaggt aaaacttact caatctggga tggatcgtat gtcgctgtct atcagtataa
     5701 actcaaacgt agctttattt ttcgactaca agatggatca ctcactcggt tcactcgact
     5761 atcagcagga gatgttaagg aagtaaccta aaacttaaat ac
//
LOCUS       DAFKHN010000126         5727 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFKHN010000126 DAFKHN010000000
VERSION     DAFKHN010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.126"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            196..921
                     /locus_tag="LY912_002707"
     CDS             196..921
                     /locus_tag="LY912_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956321.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="LY912_002708"
     CDS             911..1420
                     /locus_tag="LY912_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956322.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="LY912_002709"
     CDS             complement(1490..2938)
                     /locus_tag="LY912_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBM6956323.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="LY912_002710"
     CDS             complement(2938..3654)
                     /locus_tag="LY912_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBM6956324.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="LY912_002711"
     CDS             complement(3635..3985)
                     /locus_tag="LY912_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBM6956325.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="LY912_002712"
     CDS             4129..4902
                     /locus_tag="LY912_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBM6956326.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="LY912_002713"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="LY912_002713"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1662 a         1124 c          994 g         1947 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt tttttta
//
LOCUS       DAFKHN010000127         5689 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFKHN010000127 DAFKHN010000000
VERSION     DAFKHN010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.127"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(488..1297)
                     /locus_tag="LY912_002714"
     CDS             complement(488..1297)
                     /locus_tag="LY912_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBM6956327.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="LY912_002715"
     CDS             complement(1297..2043)
                     /locus_tag="LY912_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6956328.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="LY912_002716"
     CDS             complement(2061..2528)
                     /locus_tag="LY912_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6956329.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="LY912_002717"
     CDS             complement(2528..2938)
                     /locus_tag="LY912_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBM6956330.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="LY912_002718"
     CDS             complement(2949..3962)
                     /locus_tag="LY912_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6956331.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="LY912_002719"
     CDS             4179..4913
                     /locus_tag="LY912_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6956332.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="LY912_002720"
     CDS             4897..5607
                     /locus_tag="LY912_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6956333.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAFKHN010000128         5295 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFKHN010000128 DAFKHN010000000
VERSION     DAFKHN010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.128"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            331..1254
                     /gene="truB"
                     /locus_tag="LY912_002721"
     CDS             331..1254
                     /gene="truB"
                     /locus_tag="LY912_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBM6956334.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1258..2199
                     /gene="ribF"
                     /locus_tag="LY912_002722"
     CDS             1258..2199
                     /gene="ribF"
                     /locus_tag="LY912_002722"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBM6956335.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2594..3379
                     /locus_tag="LY912_002723"
     CDS             2594..3379
                     /locus_tag="LY912_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBM6956336.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3392..4243
                     /locus_tag="LY912_002724"
     CDS             3392..4243
                     /locus_tag="LY912_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBM6956337.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4367..4819)
                     /locus_tag="LY912_002725"
     CDS             complement(4367..4819)
                     /locus_tag="LY912_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6956338.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
BASE COUNT         1803 a          858 c         1089 g         1545 t
ORIGIN      
        1 tgattaagaa actgaaaaaa taaataaaaa aaaacggaaa aaagactgga agaatggaca
       61 gtcttttttt tcgtttttgg gaagtgaaaa ccaaactatt tacctgtaag ccacccataa
      121 atccaatcaa atggtgcaaa gaaaaaatct tccattctat tccctccttt aaaaaaaaca
      181 taacatgatt tctatttacg tgagcatgaa ttttgttacg tttttattgc cgaaaaataa
      241 aaaccgttca ttatgatgtc aaattcgtca gtaattgatg caatgtgtta taataattca
      301 gttaaatcaa aaatgaaatg gagaaaagac atggacgggt tattaacttt atggaaagaa
      361 cgcggaatga caagtcatga ttgcgtattc aaattaagaa aaatcttaca tacgaaaaaa
      421 atcggacatg ggggtacgct tgacccagac gtagacggtg tgttgcccat ttgtattgga
      481 aaagccacaa aagttatcga atatttgaca gattctggga aaatctatgt aggcgagata
      541 actctaggtt tcagtacaac gacggaagat cgatccggag aacgggtaga aacaaaacca
      601 gtagatatgt ctttatctga agaaaaaata gatgaagtga tggcttcatt tattggtgag
      661 atcacccaga taccaccaat gtactcagcg gtaaaagtca acggtaagcg gttatatgaa
      721 tatgcccgca ataatgaaac agtggagcgt cctgttagaa aggctcagat ttaccgtttt
      781 atccggacaa gtgaattgac aagagacgaa gtgacaggaa ccatttcttg gcgcttcgaa
      841 gtagaatgcg ggaaaggaac ctatgtccgc acattagctg tagatacagg caagaaactt
      901 ggttaccctg cgcacatgtc tgatctgacc cgaacagcaa gtgccggtat gtcccagaaa
      961 gatgctctga cattagaaga agtagctcaa gctgtgaaaa atgggacaat cgatgattgt
     1021 ttgctgccaa tagaaaaagg agtgaaacga ttcaaacgag tagatattac tgatgaagta
     1081 tggcagaaag taaaaaacgg tatgagactt aattatactg tatttgcgct cccagaaatg
     1141 ccgtcagaag aaattgcttt gttttataaa ggcaaagttg tcagtatcta tcagccaaac
     1201 ccgaaagaaa aaaacaaatt aaaacctagt aaagtattga gaaatgagga ataacgaatg
     1261 aatatcatca agatcagaca tccttaccaa tcagaacaaa ttccagaaga cgatgtcgtt
     1321 ttagtactag gattttttga cggcgtgcat attggacacc agaaagtcat aaagacaggt
     1381 atggaaattg cacaaaaaga aggattgaaa ttagcattga tgactttcaa tcagcatcca
     1441 tcgattgtct ttaaaaagat cgatcctagc agcgtgaaat atttgactag ccttaagcaa
     1501 aaagaagaaa aaatggccgc tttgggtata gattatttat atgaagttga ttttacttct
     1561 tcttttgctc atttagcacc gcaggaattt gttgatcaat acatcgtagg gttacatgca
     1621 aaatatgctg tttccggttt tgattatacg tatggaccaa aagacattgc agatgtcgct
     1681 cattttcctg aatatgccaa aggaagattc aaaatcgtca cagtttctaa agaagaagaa
     1741 caaggtgaaa aaatcagctc tacccgtatt cgaggattac tagacagcgg acaagtaaaa
     1801 gaagcagcaa aactattagg ttgcacatat gaggtagaag gggtagttgt ccatggcgat
     1861 gcacgaggca gactactagg attccctaca gcaaatgtca aagtaaagag cacagttcat
     1921 ttgcctaaag aaggtgttta tgtatcggaa ataaaaattg gggaaatttg gtatccagcc
     1981 atgggttcaa ttggacataa tgatacattc ggtgaaggac gggagctgac tgtagaattg
     2041 tatattttgg actttaatca agatatctat ggtgaacatg tcgcagtacg ctggaatcaa
     2101 tttttaagag atcaagtgaa attttctagt gtagaggaat tgattgaaca actcaaagag
     2161 gatgaacaag caacagctga atatttttct cagcaataaa acattatgca taaaatctct
     2221 tgtttatgta taactagcaa tttcaataaa atgggtgata aataagccca ggaaaggggc
     2281 tgtgacaaaa gtcttgtcac agcctttttt tccaaataaa tggtttttca gaagtagctt
     2341 cttcggaaat aagccgaaat ttcacaaaaa tttgagaagt aatttttgta aattacttct
     2401 tatttcttga agctggccac ttctgtcaca acctctttct ttatagaaat aaaaggacac
     2461 tagcaattca tgaaaacgat tgctaaagcg tatcatttgc tttagactat atatcttggt
     2521 gtacactcac tttaagacgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa
     2581 aggagtgggt actatgtata aggaattaga aaacaaagtc gcagtagtaa ctggtggctc
     2641 aaaggggatt ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt
     2701 caactataac tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg
     2761 cggaaaagca gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact
     2821 tgatacggct ttagaaaatt ttgggacact ggacgtttgg attaataatg ctgggatgga
     2881 aaatcagcat ccaacccatg aacttagcct tgaagattgg gaaagagtat taaaagtcaa
     2941 tttgactggc gtttttatcg gaacgaaagc ggctttaaat tactttacag agaatgataa
     3001 aaaaggaaat atcatcaata tgtcttctgt tcatgaacaa atcccatggc caacgtttgc
     3061 tcattacgct gcttcaaaag gcggagtaaa actattcacc gaaacggtag caatggagta
     3121 cgcaccaaag ggaatcagaa tcaatagtat aggacctggt gctatccgta cacctattaa
     3181 tgcggcaaaa tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg
     3241 acgcgtaggt gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc
     3301 cagttatgtt acaggtatta cactatttgc agatggtggg atgactttat atccttcttt
     3361 ccaaggtgga aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc
     3421 agttgggtgg gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga
     3481 gatattagga actggtattg gagccgtgct cgttggctta cttgttcaat tattcgcttc
     3541 tccagctggt atttcagtga ctacattttt gattagttta ctttctggtg cattctgggt
     3601 catcggacaa acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc
     3661 aatttcgact gcattacagt tagtcggaac ctcattgatt ggtgtcttcg cttttggaga
     3721 atggtctgga agtatgggaa aaatcattgg tgcagcagca atcattcttc ttgtatttgg
     3781 ttctgcttta acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat
     3841 cagtctatta gcatcaacaa gtattggtta ttgggtttac agtgcattgc ccaaactagt
     3901 tgatgcaagc ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt
     3961 gatttatgtg attttccgaa aaccaaccgc attttctgaa gacaagagtt ggaaagcaac
     4021 aatagttgga gccatcttca gtgtgtcagc attggcttat attttttcag caaatgaaaa
     4081 tggggttgct actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg
     4141 tatgtacatc ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt
     4201 attgctgatc gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa
     4261 tctcatttat taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc
     4321 gctagaattt ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaagtg
     4381 aaatatctgt ctgcatcaat aatttttcat tgatccattg actaaaattt acgacatgat
     4441 tgaagttacc accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa
     4501 gacggtcttt tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggattt
     4561 gattgattgc tgtaaaatca cgatactgaa ggttgaaacg catcgtgatt ggtgcattta
     4621 gcatgaatcg ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa
     4681 aaagattacg ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt
     4741 catgaagata atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta
     4801 ctgagtaaaa atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga
     4861 tatttgctta atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca
     4921 agtcagaaaa ttctaacttt tctttctcta aagaaattcg ttctctccta aagtgatatt
     4981 atatttaaat atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg
     5041 tattttttcc ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt
     5101 ggaaaattca aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa
     5161 aatagcagat actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga
     5221 acaaaacctg tataagctga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa
     5281 gctttatcgc caaaa
//
LOCUS       DAFKHN010000129         5231 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFKHN010000129 DAFKHN010000000
VERSION     DAFKHN010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.129"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(67..282)
                     /locus_tag="LY912_002726"
     CDS             complement(67..282)
                     /locus_tag="LY912_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBM6956339.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            506..1306
                     /locus_tag="LY912_002727"
     CDS             506..1306
                     /locus_tag="LY912_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBM6956340.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            1325..3193
                     /locus_tag="LY912_002728"
     CDS             1325..3193
                     /locus_tag="LY912_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBM6956341.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            3186..3677
                     /locus_tag="LY912_002729"
     CDS             3186..3677
                     /locus_tag="LY912_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBM6956342.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            3665..4219
                     /gene="srlA"
                     /locus_tag="LY912_002730"
     CDS             3665..4219
                     /gene="srlA"
                     /locus_tag="LY912_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBM6956343.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            4237..>5231
                     /locus_tag="LY912_002731"
     CDS             4237..>5231
                     /locus_tag="LY912_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBM6956344.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         1836 a          831 c         1070 g         1494 t
ORIGIN      
        1 tgaaaaaacc ttcccaataa agggaaggtt catgaagata ataacttttt taataattat
       61 agctttctaa tatctttcat caacttttct agtaatcatt gggaaaaatt tcaagcagta
      121 gatcgcacaa atacctacga cgatataaat gatcttcgca aaaatagttg ttgaaccacc
      181 agcaatcata gctactaaat caagttcgaa caagcctacc aacagccagt tcaaccctcc
      241 cacaatcaat aaagttaatg caatagcatc taaagttttc attagaattc tcctttctta
      301 aatgataaaa caattatata tcaaaaagag aaacattgct tatataacgc tcaggaattt
      361 tagcaatcta tgcaaaaaga tgaaaatttt ttttgctctt ccattagtac acatttttta
      421 gctgaagctg taaatttcat gtcttaattt tttttagtga gcttttatac tggatttgta
      481 agaaaaaaga aggagaggat cacatatgtc ggattggttg gatattgcag gaaaagtagt
      541 aattgtaact ggaggttcct caggaattgg aagaagtatc gtcgaaaatt tgttgaagca
      601 gaatgcacaa gtagcgaatt ttgatgtaac tgaatgccgt atacagcatg aaaacctact
      661 atctttaaaa gtcgatgtgt cttctaaaac ggacatagaa gaagggatat ataaagtaat
      721 gaaacatttc aagacgatcg atggtctagt caataatgca ggaataaata ttccttctct
      781 tctaatagat agaaatcatc caaaaagcaa gtatgaatta tcagaacaag tttttgataa
      841 gatgatcgct gtcaatcaaa aaagtgtata tttgatgagc caagcagttg gaagaatctt
      901 ggtgcaaaag ggatcaggag tgatcgtgaa tctttcttct gaatcaggat tggaaggatc
      961 agaaggacag agctgttatg ctgctacaaa agcagcgatg aacagtttta ctcgttcttg
     1021 ggcaaaagag ttaggaaaga ggaatgttcg tgtggtaggt gttgcaccag ggatactgga
     1081 agaaaccggt ttgagaacac aagaatatga agaagctctt tcttatacga gaggtataag
     1141 cgtcgaacag ctgagaaacg gttacagtcg aacaagtacg atccctctag gaaggagtgg
     1201 taagctgcaa gaagtggcgg atctagtctg ctattatctt tcagaaagat caagttatat
     1261 cactggagtc acgactaata tttcaggagg taaaacaaga ggataaagga taggggggac
     1321 gcacgtgacg ctagtaaaca gatggtacca attattgaaa ttactagtca ctcacaagaa
     1381 agtttcaatc caggaagtgc aaaaagaaat caaaaccagt aatcaaacca taaaaaaaga
     1441 tattggggag ttgaatgaag aaattgccgg tattgcaaaa atcatccaaa aaaacaaaca
     1501 ttttgaactt gaaatttatg attttgattt ttttgatgag atcatgcaag gaaaattgaa
     1561 aacagccagt gatttcaatt cggcatccaa aagaatcgct tatttactaa ataggctgat
     1621 cgaaacagag gatttcttac gtatggatga tttgtctgaa gaagtcggtg tcagcagagg
     1681 aacagtggtc aaggatctaa agacattaaa agagatgatc aatgattttg atgtaaagat
     1741 tacaggcaca ccaaataaag gactaagaat aataggagat gagctagaat tacgactact
     1801 tttattttat tttgtttctc cctacttttc agagacgaaa acagaacagt ttctagaaga
     1861 aaaacaagca atcaaacatt ttcagaagaa gacgaatgct agtaaacaag aaatcaccct
     1921 tttaacgaaa gttatcggta tttctttgaa tagaatctct agtaactatc tgttgaagaa
     1981 gcccatcaat cgttacagtg ggtgttttga atatatccaa gaattcaatg aactgatcaa
     2041 tcagttggaa gaaatctatg aactaacttt gagccaatat gaaaaagatt ttatcagttt
     2101 tcctttgaac atcatcaaca caagtataac gatgataagg aaagctaact ctgatttgcg
     2161 cttatatttc gaccccatga tgatgcgtat tcgacgatta gatctcattg atctggatga
     2221 gtccttctta tatcaagaga tgaaacagca cctctcttta ttgataaatc gggtaatttt
     2281 tcgttatcga ttgactgatt tattttatgg tgagatagaa aaaaagtatc ctttttctta
     2341 ccaaatcgct agcgaatgca tacaagcatt agaagctatc ttgcaacata agatctctaa
     2401 agtagagatc agctacctaa cgttgtattt ggagttagca tttcgatatc aaaaagagca
     2461 tttttcctct aaaaaagtag ccattgttca tacgacagga aaaggaacag cattaatgat
     2521 ccaaagacaa atcaaaagga tattggggag ggatatacaa ataacacatg tttcagaaga
     2581 acaatatgaa aaagtagatc taaacaaata tttcgctgtt tttacaacga ttccgttaaa
     2641 aaatgtaaat gaagagacac cggtgatcca tttgactaat ctttttgatg actcttggtt
     2701 aagggcacaa tggcaaaaag caaaaaaaaa gcgattagcc gggtttcatt ctactgtttt
     2761 tttctatcaa atatggaaag aaaaaaagac gtatcaagaa tatttaaaca aattagtcgc
     2821 tcctttgatc agaggctatt atgtggatga agaatttgaa aaaaggatct tgaaaagaga
     2881 atatcagcaa agcacatttg ttaacaaaga atttgctttt cctcacacaa ccaaccagct
     2941 atctcaacac attgttttat cagtagggct aataactgat caaggtttag cagaaacagg
     3001 aggaaatgga gttatttttt tatttgccat acctgaagaa atgacggctg aagttgagaa
     3061 tgaattattt gagctatacg atatcctatt tgaactcata aaaatgggaa tagatgagtt
     3121 tattgaatta gcaccgacac aagaatcatt tttaaaacta atcaaaagta aaggagagag
     3181 acttcatgaa tgatatgtat ctattcatag ttttcgcagc ttcagcttat gtgctgcaag
     3241 cagttatcag ttggaagcaa ctaaagcatt tcaatcaaac atatagcgaa ctgcgaagaa
     3301 aaggaaaagt agcgattggt aaacgacctg ggaaaatccg ttcaggcacg attgttatgc
     3361 tagctataga cgatcatgat caagttttag aagtcagaaa aatgcaaggg gttacatctt
     3421 tggcaaaatt tcattcatta cctgtctatg cgggtgaaga tatccattac atcgatcgtt
     3481 accatccctc agttcgagcg gaagatcgtt tgacacaagc agctttagaa aatgccagag
     3541 aagtatactt acgaatagag gcaggaaatg aaaaaagtga acaaccttca ttgcctttta
     3601 ttgctatgct caataatttt cggatatgga aaagtacgat caaagaaaaa aggagtgaca
     3661 aacgatggat atcataacaa aatttgctga gggatttatg aggctgttcc aaacaggtgc
     3721 agaaacattc ataagctgga tgacaggaat cgtaccagtt gtcttgatgc tgatggttgc
     3781 aatgaatacg ctgattgctt ttttaggtga agaccgagta acgaaagtag ccaaattatc
     3841 agcgaaaaat ccgcttactc gttaccttgt gttaccgttc ttatctgctt ttatgttggg
     3901 aaatcctatg tcatttacaa tggctcgttt ccttccagaa tactacaaac caagctatta
     3961 tgctgctcaa gctcaatttt gtcatacgag caatggtgta ttcccccata ttaatcctgg
     4021 agaattgttt gtatggatgg ggattgctca agggatcgaa accttagggc taaattcgat
     4081 ggagctggct atccgatact tgcttgtggg actgctgatg aactttattg gtggttggat
     4141 aactgatttt actactggat ttgtatgcag acagcaagga atcgttctta gcaaaaaagt
     4201 agagctttca gttgattaga gaaaggagag ttttaaatgt atggtgatat taagatcgta
     4261 agaggaaacg gcgggtatgg aggtcctttg attattaggc cgacaaaaga taaacacaag
     4321 ttcatctatg tcacaggtgg aggtgagagg ccaatgatcg tagataaaat agaagaactg
     4381 acaggtatgg agtctatcaa tgggttcaaa acatcaatac ctgatagtga aatcgcgctt
     4441 gcaatcgttg actgtggagg gactcttaga tgtggaattt atcctaaaaa agggatacca
     4501 accatcaata tcgtttccac aggaaaaagt ggcccattag cacaatatat cactgaagat
     4561 atttatgttt cagcagtagg gttagaacaa atacagccac taatggaaac tgatgataac
     4621 aaagaaacag taaatactgc atctccagat aaaaagtaca aatatgatac ttctaaaaag
     4681 ataaccgagc aaaaagcaga gcagcaaaac tggatagcaa aaattggaat gggcgcggga
     4741 aaagtagttg ctacattcaa tcaatcagca agagaagcag tagatacgat gatccggaca
     4801 gtgatccctt ttatggcttt cgtttccctt ttgattggtg tgatacaagg ttctgggatc
     4861 ggtaatgtat ttgctaacat tatggcacct ttagcaggaa atgcagttgg attaacaatc
     4921 attggcttta tttgttcact gccattttta tctcctttgc ttggtccagg ggcagttatt
     4981 agccaagtga ttggaacatt gatcggtgta gagattggga aaggaaatat tcctccccaa
     5041 ttagcattac cggcactatt tgctatcaat actcaaaatg catgtgattt tattccagtc
     5101 ggtctaggtt tggaagaagc aaaagctgag acagtagaag taggtgtacc atcagttctt
     5161 tattcaagat ttcttaacgg catcccacga gttatcattg cttgggtagc aagttttgga
     5221 ttatatagct g
//
LOCUS       DAFKHN010000130         5226 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFKHN010000130 DAFKHN010000000
VERSION     DAFKHN010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.130"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            118..1107
                     /locus_tag="LY912_002732"
     CDS             118..1107
                     /locus_tag="LY912_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6956345.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="LY912_002733"
     CDS             1089..1550
                     /locus_tag="LY912_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBM6956346.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="LY912_002734"
     CDS             1600..2064
                     /locus_tag="LY912_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6956347.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="LY912_002735"
     CDS             2078..2827
                     /locus_tag="LY912_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBM6956348.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="LY912_002736"
     CDS             2827..3657
                     /locus_tag="LY912_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBM6956349.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="LY912_002737"
     CDS             3657..4304
                     /locus_tag="LY912_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBM6956350.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="LY912_002738"
     CDS             complement(4402..5178)
                     /locus_tag="LY912_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBM6956351.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
BASE COUNT         1782 a          706 c          941 g         1797 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaaa tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tattgtaaag ttatatgact ttataatact tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtatcaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattaatttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgcatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatggatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttaataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgacttca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgc taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtaaat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaa
//
LOCUS       DAFKHN010000131         5191 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFKHN010000131 DAFKHN010000000
VERSION     DAFKHN010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.131"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            137..748
                     /locus_tag="LY912_002739"
     CDS             137..748
                     /locus_tag="LY912_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBM6956352.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="LY912_002740"
     CDS             821..1750
                     /locus_tag="LY912_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBM6956353.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1819..2645
                     /locus_tag="LY912_002741"
                     /pseudo
     CDS             1819..2645
                     /locus_tag="LY912_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            complement(2693..3871)
                     /locus_tag="LY912_002742"
     CDS             complement(2693..3871)
                     /locus_tag="LY912_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBM6956354.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERG
                     VKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
     gene            3969..4067
                     /locus_tag="LY912_002743"
     CDS             3969..4067
                     /locus_tag="LY912_002743"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956355.1"
                     /translation="MKERGLSGVKMVISDAHIGLTKAVKEYLLCAS"
     gene            4098..4499
                     /locus_tag="LY912_002744"
     CDS             4098..4499
                     /locus_tag="LY912_002744"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956356.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(4706..>5191)
                     /locus_tag="LY912_002745"
     CDS             complement(4706..>5191)
                     /locus_tag="LY912_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBM6956357.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
BASE COUNT         1641 a          879 c         1003 g         1668 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtctcct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gcttccttta a
//
LOCUS       DAFKHN010000132         5188 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFKHN010000132 DAFKHN010000000
VERSION     DAFKHN010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.132"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            59..913
                     /locus_tag="LY912_002746"
     CDS             59..913
                     /locus_tag="LY912_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBM6956358.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="LY912_002747"
     CDS             1010..3259
                     /locus_tag="LY912_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBM6956359.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..4437
                     /locus_tag="LY912_002748"
     CDS             3262..4437
                     /locus_tag="LY912_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6956360.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4440..>5188)
                     /locus_tag="LY912_002749"
     CDS             complement(4440..>5188)
                     /locus_tag="LY912_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBM6956361.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKL
                     ALMGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKGLES
                     RFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1789 a          764 c          946 g         1689 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actagagtaa cccgtggtgc tagttaattt
     4441 taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg acttaataga
     4501 acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac agaacgtgag
     4561 ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac tgtttttctt
     4621 tgttttccaa gtaagctgtg gtctagtttt tctgatttat ccatgttttt acgtggcgga
     4681 acggatatag taatgcccat aagggcaagc ttttcatgga ttttatggct aatatatcct
     4741 ttgtccccta ggatattggg aagattcgct tcttccgata aagtctctaa cactttcacg
     4801 tcatggacac ctggattcgt gattgagtaa gtaatcggaa agccagtctt agtaacgatc
     4861 atatgaattt taagaccata aaaataagat ttttttgttg agttatagcc aactttggct
     4921 atttgattca atagttttgc ttgtctattt ctaactggtt tacataatgg actaggaaaa
     4981 ctatctataa ttccgactag ttcacctttg gtgagcttct tgatgaaaaa gtatcgaata
     5041 atcttgatag tgtaagctaa gtttgaactt aagcgagtga atcgactcct actaggaaag
     5101 tcaccattag gaaataagac ggaacaaacc gctctatacg tggctctttg gctagtatag
     5161 ccattaatta tgccccatat aacacaag
//
LOCUS       DAFKHN010000133         5179 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFKHN010000133 DAFKHN010000000
VERSION     DAFKHN010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.133"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(139..1101)
                     /locus_tag="LY912_002750"
     CDS             complement(139..1101)
                     /locus_tag="LY912_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6956362.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1103..2542)
                     /locus_tag="LY912_002751"
     CDS             complement(1103..2542)
                     /locus_tag="LY912_002751"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBM6956363.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2727..4673
                     /locus_tag="LY912_002752"
     CDS             2727..4673
                     /locus_tag="LY912_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBM6956364.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4937..>5179
                     /locus_tag="LY912_002753"
     CDS             4937..>5179
                     /locus_tag="LY912_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBM6956365.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         1669 a          878 c          855 g         1777 t
ORIGIN      
        1 ggatttctcc actccaaaaa agtctaactt ttgggggtca ctacaagttg acaactcctt
       61 tttgtttaca aatcaattgg atatctacaa attgtatttt ctaacgaatt ttatagacat
      121 taaaaaatta atttaacgtt aaatacttcc tccagaaagt attgagattg gtaaaatata
      181 atccttattt gtcttttcgc ctttaatttt tttcagaaga atatcaacaa taagacttgc
      241 aatttcatca attggttgtc ttattgttgt caattgtggg aaaaatttct caataaaaga
      301 ggtaccatcg tatccaataa tttttaaatc ttctgggata ttaagtttaa gttgatgagc
      361 aattttcata gtgagaatgg ctgttaaatc atcagaaaca aaaataccat ctggtttgtg
      421 atttataata gttgacttta tttccatttc acgacggata gtagacagat tattaggaat
      481 tttgaaaatt tttccatttg gattttgaaa agaaaaacct agtgcacgta attctgtggg
      541 agaatccgtg ttatcatttc ctgtaatcat aatggtattt tgacaaccat ttttttgtaa
      601 agtcttagct gcaagttttc ccccttcaaa gttatctgaa gaaacaatgg aaacattagg
      661 agctaaattt ctatcaaaag caacaatagg tgctctcaca cgctcataat cagcaattcc
      721 aagattatgg cttgatgaga ttatgccatc aacttggttg gcttcaagca tttcaatgta
      781 ttctctctct ttagcaggat cattttgact attgcaaata atcgttttat atccatgttt
      841 aaataactct atttcgagat actcaatgag ttcagagtaa aagatattac taatattagg
      901 aaaaataaga ccaataagct gaggtgactt tccttgaagt ccacgtgcta aattatttgg
      961 tttataacca agagttttca tagcttcatg aactttttgt tttgtttttt ctgataaata
     1021 tcccttatta ttaatgacgc gtgaaacggt tgttgggcta actccagcta attcagcgac
     1081 atcagttaat tttgctacca ttttaatatt ttaattcaaa gtattttcca gtaggttcgc
     1141 ctgatttgat ttgaatacca ttttggtgat tttcagggaa tacacgacta gtaaacactt
     1201 tttctccttt attaataaaa atctcaatga ttgagttatc tacaaaaatg ttagcagttg
     1261 tttctttagt atcaattgag cattcacgaa tcgtaccaaa gtcagtggca tattgaatgc
     1321 ctgctttgct gcgatctaaa ataatttttc cttctttggt atctacaatc aagctaagtc
     1381 catttccttt actatcagag aaaagaagta actccgattt ctgatttgga ggaaaagtta
     1441 gttcaagctc ataagtatta tttgtttctg cttttgctgt aaattgttca gaactagcac
     1501 gtaatgatgt aatagcttct actggatatt ggtaaagttt accatctttt attgaaagtt
     1561 cttttacaag actcattgct ccctgataat catacttatc agttggataa tcgatatcag
     1621 gtagtccaat ccaactgaca atcagagcac gaccatcagg agtattgaat ccttgagtcg
     1681 catacgcttc aaatccataa tcaagatttt gaatttctga agcgcccaca agttttactt
     1741 tttctatgtc aagcgattga cagatcttaa aagtattcgg atagatattc ccataattta
     1801 gctcagattt atccaaccct tgaggacaat aaatgagaac aggttttttg tctacaaata
     1861 ctagatttgg acactcaatc atgtattctg aaccagtgcc gccaaaatca aggttgccaa
     1921 cttcctccca tgtttccacg ttattgtcat ccgctttgta aagtttgata aagcctgatt
     1981 tttctaaatt ttgtgctcca acaatcgcat acaattgtcc ttcataatta aacatttgtg
     2041 gatcacgaaa atgatcagtt acatcagcag gtttatgaat aagaacattc tcacctttcg
     2101 taatgttgta gtctttatcc atccatgctc cgatttgaag tgtatcacgt tcccaatttt
     2161 catttcgaac gtttcctgta tagagtaaga atagattccc ctctatttca tatgcagaac
     2221 cggaataagc gccgtggcta tctcgttttg tgtctggaag aagttctgct cctgttacat
     2281 gaaaatgaac taaatcatct gattcattgt gtacccattc tttcaaccca tgagcagctc
     2341 caaatggcca attttgataa aaaagcgtat attttccgtt aaaaaaagaa aaaccattag
     2401 gatcgtttaa caatcctgtt ttaggttcga tatgatagct agcacgccaa ggtgatcgtt
     2461 ttacattatc cttaatttta tccatctcat ctttagtcca atcagaataa gcacgatatc
     2521 gtatttctcg aggtaagttc atattttact ccttcaattt atctttttac aactagtatg
     2581 gtaaacgttt tccgttgaaa aatcaatcat ttcatttaaa aaaataaact atatgacaaa
     2641 cgtttgacat atttttaaga tatgctaaaa taaatttgca tttcagtgaa ccgttttcac
     2701 gtaaaaataa aaaaggagtg attcgaatga attacagtaa agtagcttcc gacgtaatac
     2761 aagcggtcgg aaaagataac cttattgcag ctgcacactg cgctacacgt cttcgtctcg
     2821 tactaaaaga tgacacgaaa gtgaatcaaa aagctttaga cgaaaatcca gatgtgaaaa
     2881 gcacatttaa aattaatgga caatatcaag tgattatcgg tgcaggtgat gttaatttcg
     2941 tttatgacga acttatcaaa aaaactggac tttcggaaat ttcaacagat gatttaaaac
     3001 aaattgctag taaagataaa aaattcaacc ccattatggc attaattaaa ttattatcag
     3061 atatttttgt tccaattata cctgcccttg ttgcaggtgg tttattaatg gcattacaaa
     3121 actttttaac agctgctgga ctttttggac caaaatcaat tgaagaaatg tatcctgcga
     3181 ttgaaggtat ttcctcaatg atccaactga tgtccgctgc accattcatg ttcttaccaa
     3241 ttttagtagg tatttcagct gctaaacgtt ttggagcaaa ccaatttctt ggtgctgcaa
     3301 ttggtatgat catgacaaca ccagatcttg gtggctcaac tgaatattgg aatatttttg
     3361 gttatcatgt ttcacaaaca aactatgctt atcaagttat tccagtttta gcagctgttt
     3421 ggatattatc tatattagaa aaattctttc ataaaaaatt gccatcatct attgacttta
     3481 cattcacgcc attattatca gtaatgatta ctggattttt gactttcaca gttattggcc
     3541 ctgtaatgtt attgttgtct aatggaatta cagacattat tgtttggcta tataacacta
     3601 ctggatttat tggaatgggt atttttggag gaacatattc acttatagtc atgactggtt
     3661 tacatcaatc atttccagct attgaaactc aattactttc agcgtggaca aatggtatcg
     3721 gacatggaga ctttatcttt gtagttgcat ctatggcaaa cgttgctcaa ggtgctgcaa
     3781 catttgccat ttggttctta actaaaaatt ctaagacaaa aagtcttgct tcctctgcgg
     3841 gtgtctcagc acttcttgga attacagagc ctgccttgtt cggagttaac ttaaaatacc
     3901 gctttccatt cttttgtgct ttaattggtt caggaattgc tacagcagta gcaggattac
     3961 ttaaagtagt tgctgtttca cttggttcag caggtttctt gggatttctt tcaattaatg
     4021 caacatctat tccattttac gtattgtgtg aattgattag ctttgtagtt gcttttgcaa
     4081 ttacttactt ctacggtaaa acaaaagctg ctggtatctt taaagcagaa gaaattgctg
     4141 aacaaacacc agttaattct tcaaaagtag caacaacaga tccaatatct actgatgttg
     4201 aatcaacaca aacaaaagtt tcatcagaaa caattgttag tcccatttct ggtaaagtga
     4261 ttagtctttc ttcagtaaat gatccagtct tttcatcaga agctatggga aaagggattg
     4321 ccattaaacc aaatggaaac acggtccatt ctccagtaga tggtactatt caactcacgt
     4381 ttgaaactgg acatgcttat ggtattaaat caaataatgg tgctgaagtt ctaattcata
     4441 ttggtattga tactgtatca atgggaggaa aaggatttac acaaaaagtt actactaatc
     4501 aaaaagttag aaaaggcgat attcttggag catttgaccg ttcaatgatt gagaaagaag
     4561 gtcttgatga tacaacaatg attattgtga ccaatacttc ggattattca gaagtaaata
     4621 tagtagctga aaatacagtc actgagggta ctgatttact tgaaatcaaa taaatatatt
     4681 tccctgagta aagatggaat tttctttcca aaatcaaata atatagatta atcaaatatt
     4741 tgagaataac attttattta atcttttcat atatcaattg tatgaaaaat tattagaatt
     4801 ttaaaaaatg ataaaaattc aaaaagaaaa aatagtagtt atttacttgt catgttacta
     4861 aataaaaaaa taatttaaat atgatatata gtcatttatt tagtgatttc attctaaaat
     4921 aaagggagaa atgtctatgc tatacggtgc aattgaagca ggcggcacaa aatttgtgtg
     4981 tgccattggc gatgaagaaa tgacgatcaa ggaaagagtg agctttccga caacgacacc
     5041 tgaggaaaca atgcctttag tcattgactt cttcaaacaa taccaagcag atttagcagg
     5101 gattgggatt ggctcatttg ggcctatcga tatccatcgc gattccgcca cttatgggta
     5161 cattacctcg accccgaaa
//
LOCUS       DAFKHN010000134         5178 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFKHN010000134 DAFKHN010000000
VERSION     DAFKHN010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.134"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(32..1180)
                     /gene="nagA"
                     /locus_tag="LY912_002754"
     CDS             complement(32..1180)
                     /gene="nagA"
                     /locus_tag="LY912_002754"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBM6956366.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1256..2092)
                     /locus_tag="LY912_002755"
     CDS             complement(1256..2092)
                     /locus_tag="LY912_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956367.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSQDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2276..3493)
                     /locus_tag="LY912_002756"
     CDS             complement(2276..3493)
                     /locus_tag="LY912_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBM6956368.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     ITSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3642..3821)
                     /locus_tag="LY912_002757"
     CDS             complement(3642..3821)
                     /locus_tag="LY912_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956369.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3876..3959
                     /locus_tag="LY912_002758"
     tRNA            3876..3959
                     /locus_tag="LY912_002758"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3910..3912,aa:Leu,seq:gag)
     gene            complement(4199..5167)
                     /locus_tag="LY912_002759"
     CDS             complement(4199..5167)
                     /locus_tag="LY912_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956370.1"
                     /translation="MNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQ
                     EQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGNALRAAHEINK
                     WFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTA
                     LPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIAT
                     LVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYIL
                     YVVIAILVLMAVKELMKSMSLQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1601 a         1054 c          829 g         1694 t
ORIGIN      
        1 aagtttagtt ttaaggttaa cttaaattat attatgcgtg gaaacgttcc acgccatcta
       61 gataagttgc ttccaatgtc atatcagggt tcaatacgat aaagtctgca tcgcgtcctt
      121 gagcgatttt tccacatgta tcatcgattt tacagctgat tgctggaatc agactagcca
      181 tcatgactgc ttgttctggt gttgctaatc cccaatctac aacattttta attgcttctt
      241 tcaatttcaa tatacttcca gctaagttgc cagattctag acgtgctgtt ccttctttta
      301 ctactactgg aaattcgcct aaattgtaat ttccatcagg catcccaccg gccatcatac
      361 agtctgtaat taatgcgaca tgatcatgtc ctgctttttc cattaggatt cccgcagcat
      421 ttggatgtac atgatggcca tcacaaatca attcagaaaa gacatgttct aaagataata
      481 acgcacccac catacctggt tcgcgatgat tcaatccacg cataccattg aaagcatgga
      541 caaatacact ggcgccagct tcaacagctt tttgcgcttc ttctagcgta gcgttactgt
      601 gacctagaga aacaactact ccttcttcag tcacttgttt gacaaactct tctacacctt
      661 gacgttccgg tgctaaagca atttttttga ttaaaccgcc tgaagcttct tgccattcat
      721 ggaaagtatc caaatcagga tccccgaaat aacttgggtt ttgtgcccct ttgtgttctt
      781 ctgtgaagaa aggaccttca aaatagattc ctttgatttt agctcctggt gcttcctgat
      841 acattttgcc gattgtctca gctacatctt ttaaacgttc tttgcttgac gtcaatgttg
      901 ttggtaaaaa tgaagtcact ccacaagata acagaccttc agacatcact ttgatgcctt
      961 ctgcatcatt atccattaca tcatgattca tatagccgtg aatatgtgta tctaccaaac
     1021 caggagcaat ccatttgccg ctttggtcaa tgatgttgac ttctccctca ggtagttctt
     1081 tggtgtattc accaaaaagt ccatcggtaa tttcaagata gcctgcatgt ttgacacctg
     1141 acgctaaaaa gaatttgtca gcatagataa aagttctcat tctattctct ccctttgttt
     1201 ttctacctct aaagtactct tatttagaga agaagtcaag aatggtctac accatttaca
     1261 aattttttga aatttgtttc acagcttgtg ctaagccttc atagaatgct gctctttctg
     1321 gttcttcttt acgcttgtat attaagcttt taagcacaaa taaatcattg aggtaatagt
     1381 agctattctt ctcttgagcc caatagattc cttgattcac ctgttctaac gcttcgtcga
     1441 tttcattttg atggaataag aaatttccat aattataaaa aatttgcgaa aattcacttt
     1501 ttgatcgttc gtcagctgat tggtgcaaca gttgaatgct tcgactcaaa taatagcgtg
     1561 cttcagccgt ttttcctgca acaccatata tttttccaat gcaactgatc agttgtattt
     1621 ctgtgtcaga aacatggatt ctttcttttt ggctagagta gcttaatgct tctttcaaat
     1681 aataaaggga ctgagagata ttttgacgca acgtgaattc gcaaacaccg agataataat
     1741 aatagcgttg aaagtcagtt gcttgataca gattttcaga aatatcagaa gattttagta
     1801 cttgttctaa cttccgataa tcacgttttt ggaaacaact atccaacagt tcaaataatt
     1861 tatcgtttgt ccgagtagtt tttcgagaga gattcatcac atgatcaatc gttaccccta
     1921 gccgttgaca aatctgcatc atcaccaata cattcggcag ttcctcatta ttttcgatcc
     1981 gacttaatac actttgtgaa caaatatctt gcgaaagcat tttttgcgtc attttttgtt
     2041 cttttcgaat ctctttaatg atcgtgccaa aggactcgat taacgtttcc ataagtatcc
     2101 tccccaaaat atgcgtattc gcattctatt cgtattttac tttaggaagt cgcaaacttc
     2161 aagaaaagac ttgcaactaa ataatatact ttagttattt aagaaaactc cactagaaag
     2221 agagcctcag tgtgtttgtc tgtggccctc ctactgaaaa atttggtttt taaaatcatt
     2281 tttggcgata ggttgctagg aattctctca ttttcttagc tgtttgtttc aaatcatcca
     2341 ttttaggaag ataaacgatt cgaaaatgat ctggctggtt ccaattaaat ccaccaccat
     2401 gtacaagtag aatatgatgt tcatgtaaaa agtccaaaac gaatttttca tcatccaaaa
     2461 tattgaatcg ctttgtatca atttttggga atatataaaa agcagctttt ggttttacgg
     2521 ctgaaagacc aggaatatca ttgattgcat tatagatata ttctctttgt tcatagatcc
     2581 ttccgcctgg caggagcagc tcatcgacac tttgataacc gcctagcgcg gtttggataa
     2641 tttgctgaga caatacattg gaacacaaac gcatggagga caacatattc agcccttcta
     2701 tatagccttt aacgtgtgac ttatctccac ttaggaccat ccagcctact cgaaatcctg
     2761 ctacacgatg agatttggat agaccattca gcgtaacaac gaacaaatca ggcgctaatg
     2821 tagcaatcgg aatatgttct agaccatcca tcactaagcg atcatagatt tcgtcggaat
     2881 aaataatcag gttattttgt cgagctactt caacgatttc ttctaataat tcttttggat
     2941 aaagtgcccc agtaggatta ttaggattaa tgataacaat agcttttgtc cgactcgtta
     3001 tttttgatgt gatatcatca atatcaggat accattctgc ctcttcatcg caaatataat
     3061 gaacaggtgt gcctccagct aatgcaatag aagccgtcca caacggatag tccggcattg
     3121 gaaccagtac ttcatctcca ttgtccagca acccctgcat acacatcgtg atcaattcgc
     3181 tcactccgtt gccggtgtag atatcattga tcgtcacatt cggaaaatgt ttcagttggc
     3241 aatattgctc aattgctttt ctagcagaaa agatcccctt ggaatctgag tagccttctg
     3301 agtcacgggc attcatgatc aaatcacgaa tgacttcgtt tggtgcttca aatccaaaag
     3361 gtgcgggatt tcccgtgttc aattttaaaa tactaatgcc ctcttcttgc atccgctccg
     3421 cttcttctag aacgggaccg cgaacatcgt aactgacacc ttctaatttg ttggattttt
     3481 caaattctct catcacttag ccaatccctc atttcaaaaa gttagaactt tccaaatttt
     3541 ttgttattta ctatttcaat atcatactcc atcctagaaa attttgccac ttatttagga
     3601 aaaacgtaag tattaaaaaa acacaaacaa gcgttaagaa cttaattgtc atgatagtca
     3661 ttccatagat tcgctgccca atccattgca attccacaaa tgattcctag cataaaacca
     3721 agcaaaaaac gtccgaatgc aagtccaatc aatacaccta agatcattcc cagtcctgaa
     3781 aattctccgt catatttctc catcttaata agtcctccca tttttgagct tgacaactat
     3841 gtaaaacctc gctatcatta ttgtgttatt attacgcaga tgtgttggaa ttggcagaca
     3901 agcatgattg agggtcatgt gagcgttagc tcgtgtgggt tcgagtccca tcatctgcac
     3961 tacaactcgt gaagttaatt ttgcttcacg agtttttttg tttgaacgtt tctttatgcc
     4021 attatataca tatcactgta tcctttacaa aaagaacgta caatcatgta aacagcctga
     4081 ggtgagtata tgaaggtcgg aaacaagcta ctcgtagaaa cttgcaagtg ttaaaacaat
     4141 taatcgaaaa acgagtaaaa tccctcacct aatactagag cgagggattt tttgtatatt
     4201 atctgtttat caccgttatt ataaaggtac aaataccaag cacggttaat ccaaattgca
     4261 taaattcatt tttttgtaaa ctcatgcttt tcattagctc tttaactgcc attagtacta
     4321 agatggcgat aacaacataa agtatatagt acgtccgcat tccggaagcc catactgtgg
     4381 gagaaaatcc cataattaac cttgaacaaa atcccattat catcaaaata actaaaaaaa
     4441 tagaagtttt cttattgtca aaacttaaat aaattccaac aattaaacat agtaataatg
     4501 ccaagactac taaagtagct atccaagtac ctggataaaa aagtgacagt ttcgttccta
     4561 actctgtaaa gagattattc aggttactac tactccaaat cattgccctt ttatttccat
     4621 tgacgtaagt aaagctttga cccattgtat taccaaaata aataatcagg tttaagaaaa
     4681 acggtaatgc agtcaatata cgcacataat agttttgaca tttcctatat gttagaagga
     4741 aaattaagaa aaatagcaat aaaaataaga tattcatgtc taaaaaaaac ggctttccaa
     4801 atgatgaaat acctaaatct aacttattaa gaaagttgaa atttttatat tcaggaaacc
     4861 atttattaat ttcatgtgca gcacgtaatg cattccctgg agttgtcaaa gagaaaatta
     4921 attctgctaa gcttattatt gaaaatactg ataacttata attatatcgt ccattgacaa
     4981 tcaaatataa actaactata cttgttagaa caaaaaaaca ggcgttgact tgttcttgat
     5041 tagttaaaaa tatcaataaa ggaatactta cccaatatat ttttctattt atttcttctc
     5101 ctcttaagag ttgaaaaaac ggataaaaag ttagtaaact aaatgctact ggccactgat
     5161 agttcaaggt ggttgctc
//
LOCUS       DAFKHN010000135         5089 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFKHN010000135 DAFKHN010000000
VERSION     DAFKHN010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.135"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(205..660)
                     /locus_tag="LY912_002760"
     CDS             complement(205..660)
                     /locus_tag="LY912_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956371.1"
                     /translation="MKKQLFKTFLLSTSILTFGSAITPSGAVFANENNISDIATYSDD
                     EYYYVLDEPVIQTRTWSKPQSWSIAKGSRTYLGIETHSRGTKLSVSANVFGMKIEIAR
                     NTSASGKFKKYRQNARITVTYRVYRKVDNKYIRTQTSTANTQYIDYIPA"
     gene            complement(1269..1685)
                     /locus_tag="LY912_002761"
     CDS             complement(1269..1685)
                     /locus_tag="LY912_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956372.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTITTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            complement(1687..1968)
                     /locus_tag="LY912_002762"
     CDS             complement(1687..1968)
                     /locus_tag="LY912_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956373.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            complement(2415..3383)
                     /locus_tag="LY912_002763"
     CDS             complement(2415..3383)
                     /locus_tag="LY912_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBM6956374.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            complement(4551..4706)
                     /locus_tag="LY912_002764"
     CDS             complement(4551..4706)
                     /locus_tag="LY912_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956375.1"
                     /translation="MKLTKLTISLVIIAGIILYFVLPANQFFLYFGIPTILIVNGVRI
                     FEQRKKM"
     gene            complement(4725..>5089)
                     /locus_tag="LY912_002765"
     CDS             complement(4725..>5089)
                     /locus_tag="LY912_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBM6956376.1"
                     /translation="FSVLFLINILNTSFSEGINPNEVNGSLLLFFLNAATYGAFLEEG
                     IFRFCMIDPQANKKQQYISILISSFLFSIVHGGGLSIFFIGIILSFVYIQTKNIWYSI
                     VAHGFYNTIGILIYLISI"
BASE COUNT         1596 a          838 c          839 g         1816 t
ORIGIN      
        1 aaaaaaaact atatttaaag agttttttta gatttacttc tttgaattca cgaatgaagg
       61 tagaatgaaa tagtataatt attagcacta aaaaaaatat atcactatgt tcaaataaaa
      121 aatatatatt tgacggtact cctaatgatg ggatagcaaa ggtcaaaacc aagtaagcaa
      181 tactaattat ccattttatt gtcattaggc aggaatataa tcaatatatt gtgtatttgc
      241 tgtagaagtt tgagtacgaa tatatttatt atctacctta cgataaactc tgtaggttac
      301 agttattctt gcattttgac gatatttttt aaattttcca cttgcagaag tgtttctggc
      361 tatttcgatt ttcatcccaa atacatttgc actgacagat aactttgtac ctcgactatg
      421 agtttctata cctaaataag tgcggcttcc tttagcaatt gaccagcttt gaggtttaga
      481 ccaagtcctt gtttgaataa ctggttcgtc taacacatag tagtactcat catcagaata
      541 agtggctata tcagaaatgt tgttctcatt agcgaatacc gctccgctag gagtaatagc
      601 agaaccaaaa gttaaaatag aagtagataa taaaaaggtt ttaaataact gttttttcat
      661 caaaatcacc tcgaatataa gatacttaag aaaacgcttt ctttatataa ttagaataat
      721 caggaaattt aatgttgtca agagggttta ttttataaaa gctgttatat taaaggttag
      781 tagacataat gtacatacta ccaagttgcc cctctaccaa tggatagaga cgctaacttt
      841 gtgatttcta attggtctag cttaaacact tcagccaatg cttgatttta tgcacttttc
      901 ttttttcatt tctttgtgca ttttgaccgg tcatttttta gagatttgtt atttttgtga
      961 gcatttgata tgctcttttt atacctcaat ctcttctttt ctaatgttaa tgaataggat
     1021 aatctcattt ttagctgctc gtgagagcag tctttttttg tttcagggta cgtcctattc
     1081 tttggatttc cgcgctatta aataaccgat acttggggat tggggtagcg ccccaaaata
     1141 caaaaagaag aagttgcata agcggatttt tctttttttt cgcaagttgg taccaacttg
     1201 caaatcttgc tggaagactg atccctaaaa agaaatcgag gaattttttt agggatcggt
     1261 ttcttttttt atctttttag aaagtttgtt gggtcaaaat ttccagaagt aaaggtttga
     1321 ttggtttctt tttgacgatt tttgggttga tttcgtcggg aaggattgag ttgattttca
     1381 attttttctt tcacttcttg atacacttta gaatttgtac cgataagaac accagtatct
     1441 tttagatata aatcagcaaa ttctgccatg atttctgtca tgatagaaat ttcttttccc
     1501 atggcattga gttttgcttg gttactggtt gtgattgtat tggtatcagg ttcataactc
     1561 atacataaaa aacgaatggc ttctgaataa ttgttgacgt ctggattttt ttcgatgatg
     1621 gaatctaaaa cgtcaacgtg actgggataa agggttacgt gtttttgaac agaagttttt
     1681 ctcatgttat attcctccga taagtgtttc aatgagttgg ttgtttgtgt gaacatagtc
     1741 attcagtatg ttcgtatttt ctgtttgaat ggcaataaat ttttcgagta ataaatcgaa
     1801 ttgatctttt ttgtaattca taagttgacg gtcaaaatca ctttcgatta gaacttttag
     1861 atatttattt cgactccatt ttttgcccgt tttggttgtg agttcctgac aacgtttatc
     1921 tattcttgca ataattttgg gattgatatt tcgaactaaa atgtccatgg aaattttcct
     1981 ttcgtatcag cgtataattt atgtatatca tacaaatata gtatttgtat agctattttt
     2041 cgccaaaaca ctatacatag cctagccaca atggcaaaaa agtgatagca aatttttttc
     2101 tgagaaacgt gataggcaca gcctatctag caccttttgt aagaaagtga taccacgttt
     2161 ccttatgctc tttcaaaatt cagaaaaatc agctgtaaaa cgagtgcagt ccgagtaaga
     2221 ttcaacgaaa aaacggggat tggggcgcca ccaaaatatc gcaacatggg tccatgttgc
     2281 tctgctcgca aaagcaaaaa gaagaataaa accagcaatt taaattaata aaaattgctg
     2341 gttttattgc cagaattgcc accatttttt ctccgtcttt gattgttttt tctgtcataa
     2401 aatctaaaaa cccctcaatc tttgaataag ttttgaagat tgtctaataa gtcttttttt
     2461 agttctgaag gaatatcgga atttatctct gatttttgtg cattattttc tttattttgg
     2521 gtattttgtt ctctttctaa cttttctaac tgttgtaaaa gttccaattt tcgcttttgt
     2581 tctttgattt tttcttgtaa tgaagtaggt gctttttcag attgaacttg ttggttagct
     2641 agttctaatg ctttgttttg ttcttctttt gttggggcat gtttgttaaa gtcgtctgat
     2701 ttttttatct caggtttaaa tgtaaattga tagccaatga caggctttcc ccgtcctttt
     2761 ccgtatttct ttttgattgt taaaccttta aagattgcag ttagttcttg tcgtattgga
     2821 ttgaacacac gttgatcaat cgtaccttgg ttgtaacttt taggaatatc aagtaattca
     2881 tgaaagtctt cttttgaaaa ataagcgaaa cctttggttc tgtattgttt tagtaatcga
     2941 aacattgttt ttgaataact gctttctaat tcattgaatt gttggagaga atagcgcacc
     3001 cattcttcaa gattattaag taagggtaag gctttttcat gaacttgtat ttcagcaaaa
     3061 ggaatatcag attttccgtc gattttaaat tgattaaata aaacaaaacg ttcacgttgc
     3121 aaaccgtcag cacttcttct accaaaacgt aaatccatta atttgtcata cgttgtttct
     3181 aaatcatcta tgaatcgaac atttgcagtt gctttataat tgcttaaatc ttttaattgc
     3241 tcgaatgtaa attgtacttt tttatcacct acatcacgca ttcttgatac gatagaaaag
     3301 aacaaattca tttcgactgg tgtaaatttt cgcaacggaa ttgtatttaa ttcatgatga
     3361 tactttacga tttcattaga catatttaaa atagctcctt tcttactcgc acaagagata
     3421 cacgttatga aatacaaaat gcctatttat ctacatctta tattaacatc gtcgatgtac
     3481 taattcaatg tacaaacaga caaaacgatg tagataaaca gacaaaacga tgtagataaa
     3541 cagacaaaac gatgtagata aacagacaaa acgatgtaga taaaagcgtc attcccttgg
     3601 gagagtaagg atatagccga cggtaaagag gtttaaaaag aggtttaaaa agagattata
     3661 aaagaggggg acaaaatttc ccgcctaaaa aaccacttct tttttctcca aacagattcg
     3721 cgcatttttc tcaactggga atcttactcc ctacagtcgc ttaaaaaggt gtgatcgctc
     3781 tgctctcaca ttatactgcg cagtcgcttc cggctccttt gctaaaaata ttcataagga
     3841 actctttgag aagctatgag ccttcgtttg agacgtttta agacagtctt agtataaatc
     3901 ccttatcttg ttcttaaagc gccttacagg cggtcagggc aagccctaac aaccctaaag
     3961 ttgtctgaat gccctctaaa attcgattta agcactctta aacctattct tatataattt
     4021 atatacttag acgtttcaaa cgtcttaaaa cgcaaattag agcttgataa agatatttgc
     4081 tcgtgtgccg acttttttaa aagtctaggc acacgccatg acaaagctga aataaactgc
     4141 ttcagctttg tcatggcgga ttcgctcact tgaaaaagtg ttcatttcgc tcgattatta
     4201 gcatatattt tttaactttt tttgctagcc aaattttgca ttagttcgct cataaatccc
     4261 accctttcag tacgtcctac ggacgtatcg ttcgtaatgt gaaagtacct ttaaaggtac
     4321 tttctacaaa actcactaaa gggtttggca agctctatat ttgctagcca aatacctacg
     4381 tatttggtgc aaataaccgc ttgtcaaagg ggcgcaagct cccccttgaa tcccccctca
     4441 aaacccacgc tccacaatac aaaaaaggct agcaaatgct agccactttt tgtaaagttt
     4501 cgcttgtttc accttcggtg aaattgttgc tttgcaacga tcaggtagag ctacattttt
     4561 tttcgttgtt caaatattct tacgccattt actattaaaa tcgtaggtat tccaaagtaa
     4621 agaaaaaatt gattagcagg taatacaaaa tataaaataa taccagcaat aattaccaaa
     4681 cttatagtaa gttttgttaa tttcatgaag tatgccacct tatcttatat agatatcaaa
     4741 tagattaata tgccgattgt attataaaat ccatgagcaa ctatggaata ccatatattt
     4801 tttgtttgta tataaacaaa acttaaaata ataccaataa agaaaatact taggcctccc
     4861 ccatgaacaa tagaaaacag aaaagaagaa attagtattg aaatatattg ttgttttttg
     4921 tttgcttgag gatcaatcat acaaaatcga aaaattcctt cttctaaaaa agctccataa
     4981 gtagcagcat ttaaaaagaa taaaaggaga gaaccattta cttcattagg atttatacct
     5041 tctgaaaaag atgtatttag aatattgatt aggaataaaa cagagaatg
//
LOCUS       DAFKHN010000136         5077 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFKHN010000136 DAFKHN010000000
VERSION     DAFKHN010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.136"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..804
                     /locus_tag="LY912_002766"
     CDS             <1..804
                     /locus_tag="LY912_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956377.1"
                     /translation="LFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLF
                     NHTPVKSLQFVWRLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGV
                     SNSIHANKDSLTLIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPT
                     THFMSNKLTIELDNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPG
                     INKVVITYQYTKLAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(949..1689)
                     /gene="truA"
                     /locus_tag="LY912_002767"
     CDS             complement(949..1689)
                     /gene="truA"
                     /locus_tag="LY912_002767"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBM6956378.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(1880..2515)
                     /locus_tag="LY912_002768"
     CDS             complement(1880..2515)
                     /locus_tag="LY912_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBM6956379.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(2662..3903)
                     /gene="sstT"
                     /locus_tag="LY912_002769"
     CDS             complement(2662..3903)
                     /gene="sstT"
                     /locus_tag="LY912_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBM6956380.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4101..>5077
                     /locus_tag="LY912_002770"
     CDS             4101..>5077
                     /locus_tag="LY912_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956381.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLI"
BASE COUNT         1667 a          979 c          766 g         1665 t
ORIGIN      
        1 ttattcttat ttctcggatt gattggtgct tttattttta taaaaaaatt aactgctgat
       61 gatttattta ttttctttct tggtgtattt gttctttttt gttcaaccaa tttatttcct
      121 tggcaacttt ttaaccatac accagttaag agtctacaat ttgtctggcg gttaaatggt
      181 ttttcttctt tatttatagc ctatacgatg agtatagtga tctattatat tttttctact
      241 aaaaataatt catggaaaat aatggtcttt acgtttcttg cactaatatt gcatctctca
      301 ggagtaagca attctatcca tgctaacaaa gattcattaa cacttatagc acctgaagac
      361 gctgttgcta tagctgaaaa ttacaatcat actgattatg caaacaaaga gtcaatctat
      421 catcctgata tgattaataa tgatcaatat ttactaggta accaggaaat aaatccaaca
      481 actcatttta tgagtaacaa acttacaatt gaattagata attcgaataa taaaaatact
      541 gtcttgacga cacctattta tcgttataaa gggcaagtgg cttctattaa tggcaaacta
      601 gtacaaacaa aattatctaa gtttggcaca actgaattaa ctattcctcc aggtataaat
      661 aaagtcgtta ttacttatca gtacacaaaa ctagcaattg cttcaagata tttatctatc
      721 gttactttga ttttattttt actttatcga tttacttttt ctaaacaaaa acaaccgaga
      781 agagaagtac aacattctca ctagattttt atttaagaaa gactttttag ctgtacacat
      841 aaacaggcta aaaagtcttt ttttatattt ctttaatttg cttcatacat tatttaacat
      901 cgatatttat actgtgaaac atgcgtttca tccattatca aagtattttt atcgataata
      961 aacttcatcc aaaaacagac cttgtgcagg gacggtttct cctgcatgtt gccgcacttt
     1021 gctttcaaat atttcatcga ttgtttctat cggcatggca cctgtgccga tttctagtaa
     1081 tgtccccatg ataatccgca ccattttata taagaatccg tctccgacaa aagtaaaatg
     1141 aagcatttct ccctttcgtt cgatagataa ttcatcaatc gtacgcactg tggatttttt
     1201 tgattttttc aatgcagaaa aaccaatgaa atcatgtgta cccactaatt tttcgcaagc
     1261 tgcattcagc ttgtccatat ccaactcttg agggaaataa aagctgtggt ttcgctcaaa
     1321 tgctgaagga atcacgttgt tccaaacata atagctgtat tttttgccca ccgcattata
     1381 tcttgaatgg aagcgctcag gcatttcttc gattcttttg atgacaatat cccgcggaag
     1441 gtaacgattc ataaagtcga tcatttctgc cagtccaatt tctgtgtttg ttttaaaatt
     1501 tgctacttgt cctcgcgcat gggtgccagc atctgttctt cctgatccaa taatttctat
     1561 ctcttcattt gtcatctgat gcaatacttt ttcgattttt ccttgaatgg ttttatcgtc
     1621 atctccaagt ctttgccatc ctgaatatct ttttccgtca tattcgattg tcaacttgat
     1681 gtttctcata ttttagtggc tcctctgtct tccatttggt cttctctcta cctttttaag
     1741 attgtagcac aaaatatagc tccttgcttc tctaagacag aagctataca agaaaactgt
     1801 ggaaatatat atttcagaaa aacaaaaaac agccaccgga tgaagtatcc gctgactgtt
     1861 caatttgacg gctcaagttt tactgtttga gatgcaagat actcaaccag gcaatgggca
     1921 cataattaaa gaaaaaactg attctttggc aaaaacctat tttattcagt aatggccaag
     1981 aatttataga aggaattctt gccagtccat aaatcgccgc aaaaagcaaa ctgatcacag
     2041 acagtccaag gtataagtgg cttacgtcca tttgcccatt ttttcgatag atcaagaaaa
     2101 gaagaactgg aaacaataaa aaaccactgt aacctaaacc tgatccgata ttatggaccc
     2161 atgtcgagac attccacgaa gattcatggg tattgatact gaacaaacct gtaaagatac
     2221 aatcacctat accatagaac gcgatggctg ctgtaactag ggtagctaac acacgagatg
     2281 tactaacaaa tgcagcatac aatgcaggca atgacaggat gaaaaagatc cctgaaacca
     2341 cagaccaaat aagaaacgct tttcttacag gactggaaac ctctccaaat acactgatca
     2401 cgctcttcat ttgatctaat tcaggataat acaatcctaa tacgtacgga gtcaaaaaat
     2461 cactcagcac gcctaataat aaaaagaaaa aaccaaattt acgtaaaaaa tccatgatac
     2521 gcctccaata acaattacct atgcttttaa ttgttattat aaacgacttt atcttgattt
     2581 aacagaaacc tctatttaca cgaacatcta tataactcat taaaaactcg aatcatttta
     2641 aaaatactaa atatctaacg ttcaacgttc acttaatcca tctaaacaat ctttcaattt
     2701 gattttttcc ccacttcttt tacgcgcgcc tagctctcct attgcagtaa acaacagatc
     2761 acttgacgaa tttaaggcag tttccattga atcctggata acaccgataa taaatccaat
     2821 accgacgatt tgcatcgcga catcattaga gataccaaac aaactacatg ctaatggaat
     2881 caataacagt gaaccgcccg caacacctga agctccacaa gcagctaaag cagacaaaat
     2941 acataaaagg actttcaaaa caaaaggtgc ttcaatccct aaagaatgta cagcagtcaa
     3001 cgtcatcaag gaaatggtaa tcgcggcacc gcccatattg atcgtagcac ctaacgggat
     3061 cgatatggaa taagactctt ttgtcaattt caatctttca gccaacatca tgtttatcgg
     3121 gatatttgcg gcagaacttc gggtaaagaa agcgggaagt gcgctttctt tcaaacaaaa
     3181 gaaaatcaat ggatagggat tttctttaat aaacaaaaac gtgaggaatg ggtacacaac
     3241 taatgcgaca aacagcatcg taccgatcaa aacaagtaaa agctgcagat actctgccaa
     3301 tccagcgatt ccagtcgtag caattgattg ataaaccaat cctaaaatcc ctatcggagc
     3361 aaatgcaata atcacttgta cgacttgtga caacgctata gatatctgat ccaccaactc
     3421 ttttgtcgat tctgaacgtg ctcgaaaagc tagtcccaac aatacagccc agaataagac
     3481 gccaaggtaa ttcgcatcaa taagagattg aacaggattt tgtgtgacat tcgtcaacat
     3541 agtagataaa acactttcca aactttgcgg tgctttttca gatactgttt cttgtaaagt
     3601 aataggaaca gtaaaaattg aacttacaat aactgctaca agtgcagaaa gcaatgttcc
     3661 cactaaatat aagatcaaaa taggcttcac gaatgtctta ttcccaattt tatgcttggc
     3721 aattgacgcc atcgtcaaga aaaaaaccag aataggtgcg attgccttca agcaactgac
     3781 aaacaacgtt cccaatattg aaataaatgt ccatgtgggg aaaaagatac caaacaatat
     3841 tccgactaaa ataccaacaa caatacgttg aactaacgac atatccaaaa acttctctaa
     3901 caaatgacca ccctttcaca attttaacaa tcattgtatc attttatgca aagaaactaa
     3961 aggtataatt ttctaaaaat tctaacaata caaacaacca tttcttgcta attttgtact
     4021 ttttctgtct acacgttgtt ttttgagata ttctaagtta ggatgttatt aatgggcaac
     4081 ttatcaggaa acgttttctt atgtttttgt ccaatttttt tgtgaggtgt ttattcttga
     4141 aaaaaataaa gaaggagagt tatggcttcc tgacaatctt tgtcgcttgt ataatgatgg
     4201 ttttacagcg tatattgatt tcagcagtca ctattcctac atatgcaaca aaccctggtc
     4261 gattctacat ctatacattt ttacaaactt ccgttgttat tggtgcaaat ttgatcccac
     4321 tttacatggg ttaccaatat caaaaaatcg cccgtttaaa agttttacat tatttaagtc
     4381 gttttgcctt tatattccta atagccacac tagtttgcaa tatctttttt tacgtacaag
     4441 ctggcagctt gaatattcgt gattattggc ttatcctaac acctatcagt cagaattact
     4501 ttacttatgc tgtttcttgt actttgcttt tttgtagtat tccttataca gttggatttt
     4561 taaataaatt atcgaaaaca acaattaaat atctactatt atttttaaca attggattag
     4621 ttggctgctc tactctattt aataaagacc cgtttgcatt acagaatgga cagagtattt
     4681 tatggatttt ttatttattt ttaatgggtt atggtttgaa agaatggaac tggaaagaaa
     4741 aggtccgcta taagcttcct caagtattta tcagcttgat tgttttattc ggtttgatta
     4801 ttttgatgac acaaatttca ctcatcatca gaggaaatac agatacagcg ctgaggtttt
     4861 ctaaaccata ttctctcttc gcaatgtatt atactttctc ttcgttttta tttttagaaa
     4921 tgctatctga taaattaggt ataaaaggaa gaggaaattt tcttgctgta tttttgattg
     4981 tcactcaagt tatatgtaat ttccctttag tttcttatcg cgtatctaca tttatgaaac
     5041 gtgaatttcc aaactcaggg aaggcatggc tgataaa
//
LOCUS       DAFKHN010000137         5002 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFKHN010000137 DAFKHN010000000
VERSION     DAFKHN010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.137"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..743)
                     /locus_tag="LY912_002771"
     CDS             complement(<1..743)
                     /locus_tag="LY912_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBM6956382.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVL"
     gene            929..1633
                     /locus_tag="LY912_002772"
     CDS             929..1633
                     /locus_tag="LY912_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBM6956383.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            1673..2230
                     /locus_tag="LY912_002773"
     CDS             1673..2230
                     /locus_tag="LY912_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6956384.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            2238..3377
                     /locus_tag="LY912_002774"
     CDS             2238..3377
                     /locus_tag="LY912_002774"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBM6956385.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            3389..3820
                     /locus_tag="LY912_002775"
     CDS             3389..3820
                     /locus_tag="LY912_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBM6956386.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            3834..>5002
                     /locus_tag="LY912_002776"
     CDS             3834..>5002
                     /locus_tag="LY912_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBM6956387.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKIS"
BASE COUNT         1662 a          756 c         1052 g         1532 t
ORIGIN      
        1 atcaaaacga ttttttgttt attgtattct ttacgaacct tttcaggaat ttcttctgaa
       61 ataagatagg taaggtcttc aattggaccg acgatatgat tactgatggt gccgaattta
      121 tcattagtta tcatcccaag tacttcagta gaaatacgta tcatctcacg tttaatgtcg
      181 gattcttgca tagttggcac gctcgttcca acatctagat ctatgttata aatacccata
      241 atataaaggt cggctcgaat gttttgtagt tgcttataag cttgtacccc aatattgatc
      301 atagattgtt tataaaaagt accgccaata ttgataattt ccaaattagg atgctgtgct
      361 aatgctatgg caatcggcgg gctattggta atgattgttg cacgaaaatc ttgtgggatt
      421 tcttttgcta aagccaagtt agttgtactt ccatcaatga tgatgacaga ttcttctttt
      481 aaaaaaggga gggctttatg agctaatgca gttttttgtt cgctagctac agtttctcgg
      541 tagttaaaat tggtaattgg cggaccaaca cgtaaagcgc cgctgtgtac tctttttaag
      601 agaccttggc tatccaaatc tttcaaatct cgtcgaatcg tgtcttcgga tacattgaaa
      661 cgttgactta aatcactagc gataactttt tgttctgcgt ttaataaatc tagaattttt
      721 tgatgacgtt ctaatttcaa catgttgcgt gctccttctt atttattctt gtttatcatg
      781 tcatttatgc gtttttatgt caataatttc cgtttttaat acactaaaaa ggcataaaca
      841 agcaaaaaca aaatattttt atgcagtttt atgttgacta gtatttgtta agcggttaca
      901 atgagggggt aattaaagga gggaatgtat ggagaaaaaa attattttgt cgccttcact
      961 tatgtgtggg gatctagcaa atttggaagg aagcatccaa gaactagaaa gtattgggat
     1021 ggattccttg catattgacg tgattgacgg ttcttttagt cccagtatgc ctttagggat
     1081 cgaaacaatc aaaagaatta gagaaatcac ttcaatgaat tttgatgtac acatcatggc
     1141 taaggataac gataacgaat tttttattgg agaaatgttg aaaattggcg tagagagcat
     1201 tacttttcat tatgaaacaa gcctccatat tgatcgatat atccagctca tcaagaattc
     1261 tggaacaaaa gtagggatag ctttgaatcc agcaactccg ttaaatgtat tacaatatat
     1321 tttacccgag attgatagga tttgtttgat gctgattaat ccaggttttg caacaaacaa
     1381 gtcagaaaaa caagtttctt acgcgctaaa aaaaattaca gatctttgcc agttagtaaa
     1441 tgagaaagag ttagcagtag atatccaagt ggatggacgg gtatcgttag aaacgatccc
     1501 gggattatta gatgcaggcg caacaaatct ggtattagga agtacaagtt tgtttcttaa
     1561 aggaaataca ttagcagaaa atcaaaaact actttatcaa gcgatgaagc aatcagttag
     1621 gaaaaatcaa tagatgtagt ggtcctgaat aatagaaatg gaggggaaat agttgagtta
     1681 taaggcggcg aaacaaaata ttgtaagaga aattactgaa acattagacc gtatttcttc
     1741 aaaagatgtg gaacaattga taaagaaaat tgaaaaagcg gaacgagttt ttttcgtggg
     1801 ggttggcaga gtactgttag cgctagaagg aatggcaaaa cgcttagggc atctaggaat
     1861 tcagacagta gtcgtaggac aaatcactga accggcaatt acagataaag atttattgat
     1921 tgttggttct ggtagtgggg aaagtgcttt cccactaact attgcaaaaa aagcaaagga
     1981 atttgggtcc caagttgccc atataggatc aaacccagac agcacaatga aagaatattc
     2041 agatcttttt attcgtatac ccgtacaaac aaaattagcg ttaccagagg aaatttcttc
     2101 tatacagcca atgactagcc tgtttgaaca aagtgttctt ttgttaggag atagtattgc
     2161 tttagtgatg atagaagaaa aagcaattga tatgtcaaag ttgtggcaat accatgctaa
     2221 cttagagtag gtgaaaaatg aaagcggtac attttggagc agggaacatc ggcagagggc
     2281 ttattggaca aattctacat cagaatggat tcgatctatg ttttattgat acgaatcctg
     2341 aactgatcca tcaattaaat caagataagg gttatactat cgaaattatt gatgaaatga
     2401 acaggagtga tttcattgat catgttgtgg cactgaatag tttatccgag ctagaagagg
     2461 tgattacagc aacaaaaaat gcagatatct taacaacatc tgttggcgca ataaatttag
     2521 taaaaattgc accgatcatt gcgcaagcct taagtaagcg atttgaacaa aagcatagca
     2581 tcaatatcgt agctaatgaa aatgtgataa atgcaagtga tgtgttgaaa aaagaaattt
     2641 attctttgct gtcagaaaaa gaacaagaga attttgatga atatgcatat tttgtgaata
     2701 cggcaatcga tcgacaatct ttaggaaaag ttcttggagg aaaaatgatc tctgttgtcg
     2761 aaccttatta tgaatggata atggatcgac agcagttaga tccaactaca tcttttgata
     2821 tgaaaaatgt aaatttggtt gatgatatgg agccttacat tgagcgaaag ctttatatcg
     2881 ttaatgctgc tcatgcggca gtagcttatt taggcgcact gaaaggatat aagacgattc
     2941 aagaagcaat ccaaaatatg gagattttca atctagtcaa gcaattttta atggagaata
     3001 tagagtactt tgtacaaaaa tatcattttt ctagagaaga attaacatct tttgtggaaa
     3061 aaacattaaa ccgtcatggg aatcagaaac tctccgatga aattactcgt gtaggaagtt
     3121 cccctattcg aaaattaggc cctaatgatc gtttaattgc tcccatagta aaactagatt
     3181 catatcattt accttacgat gcaggaataa aagtaattgc tgcgggatat cattatcgga
     3241 atcttgctga tccagaagct gaacaactac gtcgaatgat tgtaaatgat gggttgaaag
     3301 caacgattaa aaagatttct cgtttggaag gtaagctgct gaatgaagtt gtcgctgctt
     3361 atgagtccca gatttagagg aggagaatat gctaaaagaa caattgtcag gaaatacaat
     3421 gtttatggat gcgatcgatt catggcaaga ggcaatccga gtaagtgcgc gtcctttgat
     3481 aggaaaggga ataatagagg aaagctatgt acaagcgatg atacaaaatg tgttggataa
     3541 cggaaattat attatattac tgccactagt agcaatgcct catgcgcgtc cagaatttgg
     3601 gagcaaaggg gtcgggatga gctttttatg tttagataag ccagtcatgt tcccaagtga
     3661 agaaccagta aaattcttct ttaccttttc ttctgattcg ccaaagggac atttagactt
     3721 aatggccaat cttggagaat tgctgagtga tgaaaaaatg tatcaaaaat tattcgatgt
     3781 gaagacagaa aaagcattgt tagatttgat aaagaagtaa aggagagaag aaaatggagg
     3841 tagcaaacaa aaaaaaacga gtctccatgc gagctaaagt tcaagcgatt ggcggtttct
     3901 taacaaatat ggtattgcca aatataggcg catttattgc atggggaatt gttactgcat
     3961 tattcattcc aactgggtgg ttcccaaatg aatctctgaa tgaactcgta agtccgacag
     4021 tcagctatct attgccgtta ctacttgcct atactggtgg tcggatggtt ggtggtacac
     4081 gtggagctgt tttaggtaca atcggaacaa taggtttgat tattggtgct gacataccaa
     4141 tgttcatggg agcaatgatt atggggccac ttggtgggtg gatgatgaaa aaaacagatg
     4201 attttttaga tgggaaagtt cctgctggtt ttgaaatggt cgtcaataat ttttctatag
     4261 gaattattgg tttcatactg atgtgccttt cttatctggt agttggacca ataatccaat
     4321 cagctaatca atttgtaacg agtgcaattg aagcattagt ttcaactggt tttttaccga
     4381 tactgtcctt aatcaacgaa ccggcaaaag tcttattttt aaataatgtt attgaccaag
     4441 gtgtttatta tccattaggt atgcaacaaa cattagaggc aggcagatca atttatttca
     4501 tggtagcatc aaatcctggc cctggcttag gactattgtt agcttattct ttatttggta
     4561 aaaaggcagc aaaacagaca gcaccaggtg caatcatcat ccattttttc ggcggaatac
     4621 atgagattta ttttccatat gtattaatga aaccactcac tatattatct atgattgctg
     4681 gtggaatgac aggaatcatc acttttgaat tatttgatgc gggcctggta gcaggtccaa
     4741 gtccaggttc tattttttct tatttagctc taacgcctcg gggaaatttt ttgggtgtca
     4801 tggcgggagt ggtcacagca acactggttt ccttttttgt aacatcagta attttaaaag
     4861 cagataaatc aacagatgaa gacagaaatt ttgaactatc agttcaaaaa tcgaaaacga
     4921 tgaaatcaga aggaagaaaa ttattaaaag aagaaaatgc tagagaaata tgtaccgaga
     4981 aaaaagagat gaataaaatt tc
//
LOCUS       DAFKHN010000138         4933 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFKHN010000138 DAFKHN010000000
VERSION     DAFKHN010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.138"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            85..972
                     /locus_tag="LY912_002777"
     CDS             85..972
                     /locus_tag="LY912_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBM6956388.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="LY912_002778"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="LY912_002778"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBM6956389.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="LY912_002779"
     CDS             2274..2720
                     /locus_tag="LY912_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBM6956390.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="LY912_002780"
     CDS             2993..4345
                     /locus_tag="LY912_002780"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBM6956391.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="LY912_002781"
     CDS             4516..4803
                     /locus_tag="LY912_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956392.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1395 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt ttt
//
LOCUS       DAFKHN010000139         4835 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFKHN010000139 DAFKHN010000000
VERSION     DAFKHN010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.139"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            59..174
                     /gene="rrf"
                     /locus_tag="LY912_002782"
     rRNA            59..174
                     /gene="rrf"
                     /locus_tag="LY912_002782"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(227..697)
                     /locus_tag="LY912_002783"
     CDS             complement(227..697)
                     /locus_tag="LY912_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBM6956393.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(856..1314)
                     /locus_tag="LY912_002784"
     CDS             complement(856..1314)
                     /locus_tag="LY912_002784"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBM6956394.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1485..2630)
                     /locus_tag="LY912_002785"
     CDS             complement(1485..2630)
                     /locus_tag="LY912_002785"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBM6956395.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2643..3560)
                     /locus_tag="LY912_002786"
     CDS             complement(2643..3560)
                     /locus_tag="LY912_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBM6956396.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3988..4551
                     /gene="efp"
                     /locus_tag="LY912_002787"
     CDS             3988..4551
                     /gene="efp"
                     /locus_tag="LY912_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBM6956397.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4652..4822
                     /locus_tag="LY912_002788"
     CDS             4652..4822
                     /locus_tag="LY912_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956398.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
BASE COUNT         1515 a          885 c          923 g         1512 t
ORIGIN      
        1 tgacttcaaa tccagttttg agtgaacaaa atttactcaa taaaagataa caccacagtg
       61 tggtggcgat agcgagaagg atacacctgt aaccatgccg aacacagaag ttaagcttct
      121 tagcgccgat tgtagtgagg ggttgcccct tgtgagagta ggacgtcgcc acgcaaaggc
      181 aaaaagatga actagaaata gttcatcttt ttttattttt attaagttaa agaacggatt
      241 caattgcagc ggtcattttc aatggagaag tttgtggtgc aaatcgttcg attactttgc
      301 catttctatc aatcaaaaat ttagtaaaat tccattttat tgctttagtg acagtaccag
      361 gagcttcatt tttaagataa gtaaaaagag gatctgtatt ttctccattt acgtcaatca
      421 attgatgcat agggaaggta acgccataag tggttttaca agcttctgct gcttcagtcg
      481 ctgaatctag ctcttgttta aattgattgg aaggaaagcc taagataacc agaccttgtg
      541 tctgataagc ttggtaaagt tcttctaatt gtttaaattg aggtgctaga ccgcattttg
      601 ttgcagtgtt aacaatgatt atcggtttgc ctgcatattt tttcaatgaa tagacagtgc
      661 cgtcttctaa agtagtttca aaattataaa tagacataaa gttttctcct ttctatttta
      721 tataataaaa agagcgctaa actgaaaact agctatttgt tttcccgttt agaactcttt
      781 tcagacaata aatatttaat aaaatacgaa gataagatag ctatattgct tctcatcttt
      841 acgttctttt agaaactatg cttctacttc agaccattca tcgcgttttg ctaaaaattc
      901 acgagccaaa gcttgtgcac cttctagtgt atggctggca gcccagccac attgtgtttc
      961 attgcttgca ggtacttcag tagcttcaag aacatctttc attgttgctt caagaacatc
     1021 taaaatgtct tcgtagcttt catgattcaa tacagtcaag taaaagcctg tttggcatcc
     1081 cattggagac cagtctacga tgtaatctgc gtgattgcgg attagttcgg cagtcaagtg
     1141 ctcaagtgaa tgtagacttg gcatgtccat gtgttcttta tttggttgtt taaagcggac
     1201 gtcgtattta atgatgacat cgccatgcgc acccgttttt cgatcagcta cacgtacata
     1261 aggtgctttg acttttgtat ggtcaagatt aaaactttcg acattcattc tcatttgtaa
     1321 gactcctatc tgtttgttca ttcgttttga tgcttttcac taaagaatta tttagtgaaa
     1381 tttacaaaaa cgtctttcta cttgattcta acacttatcg tttccaaggt gtagcaatct
     1441 gaaatatttt ttagattttt ctgctaagtc gtttattggg acttctagtt cttgattctg
     1501 tcaaatgcct gagctaaatc gtttatgaga tcctgaccat actcaattcc tacagaaaga
     1561 cggatcaagc cgtcctttat gccagcctct tctcgttttt cttttggaat agacgcatga
     1621 gtcatgacag aaggaatttc cactaaactt tctacgccac ctaaactttc tgctaaagta
     1681 aatagttgga gtgattcaac aaatggaata gcagattctt cattttttaa agtaaaagaa
     1741 atcattccgc taaagccgct catctgctgc ttagcaactc catggagttc atgatcgggt
     1801 aatcctggat agtagacctt ttctactgct ggatgagaaa atagaaaatc agctaccaca
     1861 aaagcatttt tttgatgttc ctccatacga acacttagtg tcttgattcc gcgctgaagt
     1921 aaccagctat cttggggacc aagtacggct ccgatagcat tttggtaaaa tccgatctga
     1981 tcggctagat ctttatggtt agaagtcact aaaccagcta ctacatcgct gtgtccgcct
     2041 agatatttgg taccgctatg gacaacgata tcagaaccga gatctaaagg tctttgaaaa
     2101 taaggagtag caaatgtatt gtcagcaata actatcaatc catgttgatg agccagagtg
     2161 gcactttttt ctaaatcagt aatctttaga agcggattgc taggtgtttc aagataaagt
     2221 gcttttgtat tgggtttgat ggattgttct attttatcaa gattactcgt atctatgatc
     2281 gtgtactcga gaccattttt agtaagaact ttgtcaaata gacggaatgt tcctccatag
     2341 acatcatctc ctaataagat atgatcgcca gcttgaaaaa gagaaaaaac ggcatgaatc
     2401 ccagaaagac cagaagaaaa agcgaatcct cgaacaccgc cttccaaatc agcaatcagt
     2461 tcttccaatg caaaacgagt aggattacca gatcttgaat attcatattg tttaggctgg
     2521 ccgacgccat cttgccgata agtggatgtt tgataaatag gtacactgac agctcctgtt
     2581 gtgggatctt cactgatgcc tccgtggatc aattttgttt gaatgtgcat gtttctttcc
     2641 tcctataagt aaatgttttt tgataaatag cggtctgctg cgtctggaaa aatcgtaacg
     2701 acacgatgac caggtggtaa acgacgaatt tctcttaatg ctgctgcaaa agccgcacca
     2761 ctcgaacttc caactaatag tccttgttct cgtgctaact gcctagtata gttaaaccct
     2821 tctacatcag agattgtctc gatctgattg attgaaaggg gagaaagaaa cggcggaatg
     2881 aattctacac cgataccctc aatttcgtga ggggctggat caccaccatt taacacagag
     2941 ccctctggtt ctacaccgat tattcgaatg tcgggatatt tttctttcaa aaaggtagaa
     3001 gttccagcaa aggttccacc actcccaatt cctgctacaa aactatggat attttctttg
     3061 atttcatgaa agatttctgg ccctaacgta tgatagtaag cagcaggatt atctttattt
     3121 tcaaattgaa gaggcagata gctgtttgat atctcctctg caagtttttt acttttgctg
     3181 atggcaccga tgattccttg ctcactagga gaatggatga tctttgctcc caatgctttc
     3241 atcaattgtt gtttttctaa gctaaacttc tctggaacaa caaaaaccgt tcttaatttg
     3301 tatgtgagtg cggccagagc gatcccaatt cctgtatttc cggcagttgg ttcgatgatc
     3361 gtcgtttttt cattgatttt tccttgggca aatccttctt tgatcaaata actgcccaat
     3421 ctatctttga tacttcctcc aggatttaaa tattctagtt ttgcataaat agcagaacct
     3481 ttaggcatag aatagtgctg attgtcaaag cgataaagcg gtgtggaacc aatagcttct
     3541 gtaattgtcg agataatcat gtgggcctcc taaaaaaaga taataaaaaa aggagctgac
     3601 tattaaatca gctccttgaa agacatagag aaaaattgag tagataaaaa gataagttac
     3661 ctggtactca ttctatgaag ggcaattaat agacatgaca aatagtatgc tgcttttatg
     3721 caccatacaa cagcaacgat tcaattgttt ttggttgctg actgtcatgt gtatccctcc
     3781 aagtaaaatt tttattaacg atagcatgaa aaaaaataaa agtcaaaggc ttgaaagaaa
     3841 aaaatatttc gatagcatcg tttacccgtg tttatttttc tgacaaatag gcatgagacc
     3901 ttaaaagata gagaatactc tagttttctg gccggttgtc tgatacaata aagttgatta
     3961 tgataaagaa aagaaggagc aaaaataatg atctcagcaa gtgatttaag agccggtatg
     4021 actttcgtac aagacggcaa actgattaaa gttctggatg caagccacca taaacctggt
     4081 aaaggaaata cagttatgcg tatgaaactg aaagatgtcc gttcaggtgc aacatacgac
     4141 acaacgttca gaccagaaga aaaatttgaa aaagcacata tcgacacaaa acctgtacaa
     4201 tatttgtaca cgatggatga tacagctttc ttcatggatt tggaaacata tgagcaatat
     4261 gaaattcctg tagaaacagt agaagaagaa atgaaatata tcctagaaaa catggaagta
     4321 aaaatccaat ttttcggtag cgaagtcatc ggcgttcaat taccaacaac tgtcgtatta
     4381 cgtgttgtgg aaacacaacc ttccatcaaa ggtgcaacag tcactggttc aggtaagcca
     4441 gcgacaatgg aaactggctt agtagtcaat gttcctgact tcatcgaaac agatgaattg
     4501 ttggaaatca atacagcaga aggttcttat gtaaaacgtg cgtcaaaata attcgctaac
     4561 ggattgataa gaatttgaaa acagagcttg acctcttgaa aggcagatca tcggatctgc
     4621 ctttcaagag gttttttgtg gaatcagcaa attgaaaaat aaaaaagtat ttgattttat
     4681 ttatattttg aaagatgaat ggcaaaagct agagaaagaa aaaactgcac ttatttatga
     4741 agaaattgaa atgattcata aaattgaaaa tatccgaact attccgaact atattgaagc
     4801 gaaaatattt tttcatcact aaatagtgtt gaatt
//
LOCUS       DAFKHN010000140         4744 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFKHN010000140 DAFKHN010000000
VERSION     DAFKHN010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.142"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..142)
                     /locus_tag="LY912_002789"
     CDS             complement(<1..142)
                     /locus_tag="LY912_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956399.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQ"
     gene            complement(183..437)
                     /locus_tag="LY912_002790"
     CDS             complement(183..437)
                     /locus_tag="LY912_002790"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBM6956400.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKPIMDRLQLTRQKN"
     gene            complement(548..802)
                     /locus_tag="LY912_002791"
     CDS             complement(548..802)
                     /locus_tag="LY912_002791"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956401.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(995..1270)
                     /locus_tag="LY912_002792"
     CDS             complement(995..1270)
                     /locus_tag="LY912_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBM6956402.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(1242..2195)
                     /locus_tag="LY912_002793"
     CDS             complement(1242..2195)
                     /locus_tag="LY912_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBM6956403.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2807..4300
                     /locus_tag="LY912_002794"
     CDS             2807..4300
                     /locus_tag="LY912_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBM6956404.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            4435..4731
                     /locus_tag="LY912_002795"
     CDS             4435..4731
                     /locus_tag="LY912_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBM6956405.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
BASE COUNT         1531 a          795 c          827 g         1591 t
ORIGIN      
        1 attgctttac ccatttgtca aatgctgaag ccgttagttc atattctcga atgatttcta
       61 cacgtggctt tccagctaag taaagattga cgatttgttg cttgaattct tgtgaaaaag
      121 ttcttcgtgt tctcttagac ataaaaattc ctcctggtat gttttcttct agtctacaca
      181 ccttaatttt tctgtctagt taattgtagc ctatccatga tcggtttatt agacctttga
      241 ggtctatatt ttttaactac aatcgacctt aaatttaatt gtttcattag cttttggaca
      301 tgtttaagag atactgaaat cccttctttt aataaaactt gatggatctt tgtggcacca
      361 tagcgttgtt tattcgtaaa aaaaattgtt gaaatcttct ttttcaactt attatttctg
      421 atttctgtag ctgtcaacgg tttattctta taaaaataat agacacttct agggatttct
      481 aataaccgac acaacaaaga aacagtgtaa tccttacacc atttttcaat aaattgaaca
      541 agcgaattta ggttttccga gagaatatgg ctgcggcttt ttttaagatt tcaagttcct
      601 catttaaacg agcattttct tttctcagtt cagctacttc ttttccagtc agtcctgtgg
      661 actgatcagg taaatataaa ttcttccatt tgtaaatcgt tgcttcagat aagccatatt
      721 ctttcgctaa ccctcgaaca gaacgtccag tttgattcag ttcaacaatc atttgtttaa
      781 aattttcttc atatcgggtc ataaaaattc atcctctcgt agataagttt aatttattct
      841 tgtctctacg aaaagctgtc taagatttga tactaacacc aaatgttgta tacccccaaa
      901 caatacacat attttgaagg attaggatta ataaagctaa aaatatagta agtatactaa
      961 atatatttac tatatctagt atacttacta tattttaatc ttttgatcgt ctattatata
     1021 taatccgttc ctcgtcgttt aaagtatcaa cataggcgtc cattgcaagt ttgactattt
     1081 catacatagg aatatctttt gcataactaa gatcccgaat ggtttttagt acgggaggat
     1141 ctacttgaac tggttttctt tctttcgcag tgtactttcg ttcccctaac tcgacattaa
     1201 tatcatcttt aattgaaata tcttcagcac caattttctt cttatctttg ttcgttggta
     1261 ataatgccat ttagtttaat ctcctttcca agaggtagga tatgattggc cattgagtca
     1321 gcatatttag gtgtataatc aaatccttca atatcaccat gttgttcata gtattcaatt
     1381 ctttcttcta attctgtaaa gatgtctgca aaaatagccc accatcttcg atctacataa
     1441 tcatttaatt ggataccatt ctcaccatac atttctaacc gatccgagcc tttaacaatg
     1501 cttttaaaaa tgtttgattc accatactta tcaattgttt tttgatagtt tgcgtgttga
     1561 gaggaacgtc gcactgagaa aagaacaggc aaaattccaa tgatttgaag atgagactct
     1621 tcaaaattcg tgacaatcgg aactaaaact ttattaataa aatcttctgt tccttccatt
     1681 gcgtaccgtt ttaattcttg cattgcaata atataatctg cagcagttaa gaatgcacga
     1741 accacattat ctgttgatgg tgggcagtcg ataaagatat aatcgaaatt ttttctcaat
     1801 tcttctaaag gtttaatgaa ggccaatgat ctcttacgac gatcaggata tttttcggac
     1861 aagtattcat taagttcttc agatccagga gagccagcca taatatataa atgtggactt
     1921 acttgagtaa tacctgaaac ccagtcccct tttttgattg ctgcagacat ggatcgatca
     1981 aagctagtaa tttgatacgt tgatccaatg ttggaagtag tatttctttg ttggtcataa
     2041 tcaattagca acacgtcttt ttcaaaaagt tgactagaaa caatcgctaa taaatcattg
     2101 tctgtagtct taccaatgcc gccttttcta cctgtaagca ttacaacttt tcctagttta
     2161 tctgatgttt taaatgcagt ccgtaagttt tccatagttc cctccaattt cctatactaa
     2221 atatatttag tatacttcat atacttaata tattcgatat atctaatata ctccaaattg
     2281 ataagaattc agactttata aggaatatag tggatatact aaatatattt gctatattca
     2341 gtatatcaga tatattcaaa atgtcaaaat atatttgtgc gttttgcgtt gacaatttag
     2401 agtgaaaaga ggtaaactta attctataga aaccacagat aattcactat ttacaaagta
     2461 gcaaaagcag tggtactctt taaacagaaa aattacataa aaaaaagaga cggaaataat
     2521 tgattttagc agaatcaatt atttctgaat cacatggtta ggacatgtgt tcacgctcgt
     2581 ctcaagaata tgtaagtagc taccaactac ttatattaaa agttgatcgg ataccttttc
     2641 cgattgcctt tattctacca aaaaaaggcg agcaactcaa cagaagaacg tttatttagt
     2701 gtacttaaat taaatattct taaacactga agagagaaca catactatgg ctgagattaa
     2761 agctaaactg tgttctcttt ttgtttgaga aaggacgtta caatcgatgt tgagcgaaat
     2821 ttattcagct attcttaaaa acggcttacg tacatacaaa tatcgaaaca gcaccatgaa
     2881 acctgcaggt catattgatt ccagtaggag tggtgctatc tttgcgtacc gtagcaagca
     2941 attaatgaat gttgggcgtg gtatggtcat tacttcggaa gaagctattt tagagaacga
     3001 aaagaaacta acgcattgga cacctaatac ctatcgcttt ggtacttatg cggatgatta
     3061 tcgaacagtg gttaaaggtc attctgagaa aaacttaagt caaatcaaca catttgtagt
     3121 tgatatcgat tcaaaagaga accatcaagg cgaaattatt ttagcctgtt tagatcaagt
     3181 gggctacatg ccaacgctaa ttttagaatc agatcatggt tatcaagttt attttgtact
     3241 aaagacacca ggctatgtca caaagaaaag caatttcaag gtgatcgatg tagcaaaaaa
     3301 aatttcaaaa acaattcgtc tacagttggc tgaaaaattg tccggagtgg atctaggatg
     3361 taaccacttc ggaattgctc gattcccaca agaaaataat attgttttta aagaaatgaa
     3421 ctatcagtat tcttttgctg actggattca atggtcgatg aagcttgaat cagatcaaaa
     3481 aacaaaagaa gatcgagaac gaaaactaat tgtctttcct gagaaaaaag aaattcgtca
     3541 agtagatgaa ccgtggttcg atatgttact tcataaagca aacatcgtcg gcggagaagg
     3601 acgtcttggt cgaaataatg tgattttcac gctttcttta gcttattact cttcaggtta
     3661 tgcattggat acttgcgaat acaatatgtt cacattcaac gaacggttac aggaaccgct
     3721 atctgaagca gaattagtaa agattgtacg tagtgcttat tctggtaatt atcaagcagc
     3781 aagcagagaa ttcattattg aattgtgcca gcaatgggtt tcaccaacct taaaaaataa
     3841 tgatctgttc attcaacgac gtggctggtg gaaatttaaa aagccacgag atcaaagaaa
     3901 atatagtcat aaaaatgaat ggaaagaaga tctattggct tatctaagcg aaaaaagtct
     3961 tgctagtgag ccttatttga acctgtcaaa aaaagaattg gcttcacaac taacgatgcc
     4021 caagcgaaca cttgataaga tcttaaatga gttacgagag gagaataaag tcttctacaa
     4081 ggtaacacga ggaagaaatg gcggaatgat cattgcttca gtcaaaacgt tgttcgcgag
     4141 ggttattcaa ctaagtaaag aaaagagact agattattca acaaggatca cagaggtatt
     4201 tggactcaac gagagcttag tagaagagac atttagacaa ttatcaaccc ccttgaaccc
     4261 tcttaaagaa gtgaatcttt ttgaagtaga tacaggttga aaaataaaag gtgcaaattg
     4321 ccttatacaa tatatctatg atacttctgt aggtgttgct ccctttgcct agctacgtgt
     4381 aggtggtata cttataactg cgtatgcagt cttatgtatc atggaggaag ttgtatgtcg
     4441 ttaaaaaatt atgtctattc acatcctgtt aatgtgttta tcattggtcg tttgggatta
     4501 tctgtggaag tgttctgtga gctttatggt tttaagcagg ggactttgtc ttcttgggtt
     4561 accagggaaa aaacagttgc ttctttgccg attgagtttc ttcatgggtt gtccttagct
     4621 tctggggaga ctatggatca ggtatatgat tgtttgtgtg tgttagagca ggagtatatt
     4681 gagtataaaa tagctaacga gttaagaaaa aggaagaagt atatccagta gtagttttta
     4741 ttta
//
LOCUS       DAFKHN010000141         4729 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFKHN010000141 DAFKHN010000000
VERSION     DAFKHN010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.143"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(1..355)
                     /locus_tag="LY912_002796"
                     /pseudo
     CDS             complement(1..355)
                     /locus_tag="LY912_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            425..586
                     /locus_tag="LY912_002797"
     CDS             425..586
                     /locus_tag="LY912_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBM6956406.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            605..1882
                     /locus_tag="LY912_002798"
     CDS             605..1882
                     /locus_tag="LY912_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6956407.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1892..2548
                     /locus_tag="LY912_002799"
     CDS             1892..2548
                     /locus_tag="LY912_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6956408.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2548..3924
                     /locus_tag="LY912_002800"
     CDS             2548..3924
                     /locus_tag="LY912_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBM6956409.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(4210..>4729)
                     /locus_tag="LY912_002801"
     CDS             complement(4210..>4729)
                     /locus_tag="LY912_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956410.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSLEQLLSTVCDVGDISFSIRNQLRFKRSLPVSGNINVYFTKARFKRLIAITVSSIV
                     MFLWLFRMGVIP"
BASE COUNT         1777 a          586 c          833 g         1533 t
ORIGIN      
        1 tgacgagaaa tatttagaat tttgcacatc gctgatatgg aatatttatg cttgttggca
       61 tcaattactt gtcttttcgt ccgaatatca gcgccgcttg ctttaaaata tcattctcca
      121 tttcgagttg cttatttttc tttcttagtg cgatcaattc tgcttgttct ggtgttaagt
      181 tgtctctttc tttgaatgag cccgttgatt gtgcttgctt catccattta tcgaaagaag
      241 aaggcgtaag ctcatactct cgaataattt ctgcgcgagg cttaccagcg agatagagat
      301 cgacgatttg ttgtttgaat tcttttgaat aggttcttcg ttgacgtctt ggcatgaaaa
      361 atcctccagt gtgtttttta ttattctaca caccttattt tttctgtcta gtctagtgta
      421 gccgattcag gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat
      481 gaataaagat tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa
      541 aaatgcttgt ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag
      601 gaaagtgata aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat
      661 ttttatcata ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc
      721 aagcaatgaa atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa
      781 aaaagatggt aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat
      841 tgaagaaaaa ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag
      901 cggagaacaa agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact
      961 cgaagctaca aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa
     1021 agaaggtaaa aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc
     1081 taaacaaaac aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa
     1141 aagtggaaaa ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca
     1201 ggaaacatat acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc
     1261 aacaagccaa gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat
     1321 gtattctggt agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat
     1381 tgatgagtca aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc
     1441 agtgagtgga ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat
     1501 ggttgttctt tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat
     1561 attcttatct attggaacat ctaagataca aattataatg caatttatat tcgagttaat
     1621 attcatatcg ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt
     1681 aattgtagat ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa
     1741 taatagtagt tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag
     1801 tattattgtt ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga
     1861 aatcttatca aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc
     1921 atatagttat gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact
     1981 tgggaagttt tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt
     2041 acttgctgga cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca
     2101 aaataaagga tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa
     2161 tttaatagat tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga
     2221 aagtatcttg tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt
     2281 atctggtgga cagcaacaaa gagtagctat tgctagagca ttggtatcag atgctccaat
     2341 aatactagct gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa
     2401 tatattaaag acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa
     2461 ggaagtagca gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt
     2521 aaataaaatg aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga
     2581 aaaagtttaa aatcattaat tatcatatta gttattttat ctatgtcaac tttaagtctc
     2641 attagtttat ctattaaaga tgctacggac agagcttcaa aagaaacatt tgctaatata
     2701 acaaatagtt tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg
     2761 ggaaatgtaa aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat
     2821 gtaaaaagaa taaacagtgt tgcagattta gttgattatg atattattga aactcaagag
     2881 actcttgcga atcaatcacc tgaaagagca aagaatttta aaagaacagt tatgttaact
     2941 ggggttaacg actcaacaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa
     3001 ggaaagcatt tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa
     3061 aaaaataacc ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat
     3121 aatgagaaag gtgcagatga aacagtagaa gtagaaatta aaggtctatt cgatgggcat
     3181 aatagcggtg tagtaagtgc agcacaagaa ctatacgaaa atacattaat cactgatatt
     3241 catacagctg ctaaagttta tggtaatacc gaagatacag ctgtatacca agatgcaaca
     3301 ttctttgtaa aaggtgataa gaatcttgat agtgtaataa aagatcttgg gaaattagat
     3361 ataaattgga gagaatataa tttgattaaa agttcatcaa attaccctgc attacaacaa
     3421 tctatatcag gtatttactc aatttcaaat aaattatttt ttggctcatt aatatttgca
     3481 ggagttgtag tttcattatt attattctta tggatgaatg ctagaaagaa agaaatagca
     3541 gtattactat cattaggtat atcaaaatta gaaatttttg gtcaattcct aattgagatg
     3601 gtatttatat caatccccgc attcgttggt tcctatttct tagctcaata tacagctgac
     3661 aagcttggga ataatatatt gaataaggtt actggtgata tagctaaaca aatagctaaa
     3721 caatctgcat ctagccaatt aggtggtggg gcagaagctg aaggatttaa caagacatta
     3781 tcaagtttag atatcaatgt attacctaaa ttcatgattt atgtagttat atttatgagt
     3841 ttagtacttc ttgtatcatt gattatttct tcattcaata tattaagaag gaatccaaaa
     3901 gaattattaa ttgacaataa ttaaaatttt cggtgctttt tagcaccaaa aatgagagtg
     3961 taatataaac cgtgtaagta accatcaatc ctaggcgggt ggttgcttca cggtttttat
     4021 ttttctaaaa taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat
     4081 gctgagaagt tagctgaatc cattttgaat acttatcaac ccgaatctgt agaggatatg
     4141 caagatgttt taaaagatgt gtttggtccc ttatttgaaa aaatgcttca aggagaattg
     4201 aataaccatt tagggtatga cgcccattct aaagagccaa agaaacatga caatcgacga
     4261 aacggttatg gcaataagac gcttaaaacg agctttggta aagtaaacat tgatgttccc
     4321 agagaccggg aggcttcttt tgaacctgag ttgattccta atagaaaacg agatgtctcc
     4381 gacatcgcag actgtagaca aaagctgttc caaactcgta actcgagctt ggaacagctt
     4441 tttatctact tcgtttcgaa tttttgaaca aaaaaataaa ggctccttgc ctttccatag
     4501 ccaggtggct aatttcttta aattcattgc agcaaacact agcatcgtat gcgtcgcgac
     4561 tttttccaag cctcgatact tggtccaacg catcccatgc ttttcttttg catccgcaaa
     4621 tattcgttca atcgtttgtt tccgtttttt gtaaattgat ttattcagat ctgttaggcg
     4681 aagatgttcc acttcatcca tcagatctcc ccaaacatgt ctcgtgatg
//
LOCUS       DAFKHN010000142         4598 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFKHN010000142 DAFKHN010000000
VERSION     DAFKHN010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.144"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..1180)
                     /locus_tag="LY912_002802"
     CDS             complement(<1..1180)
                     /locus_tag="LY912_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HBM6956411.1"
                     /translation="MNHQEAKQFFLKTSSFFSTSLPNYIDLSVGIEKAVDLLKNKSFT
                     ELVRHKRSLSEAVDVNHRILANKDGNYAWRPLQILHPLVYVDLVNGITQKNNWNHIKN
                     KFEEFQADKRIECISLPVESISSKSDTAETILNWWENLEQAQISYALEYDYCIHSDIT
                     DCYSSMYTHTIPWAVHSKEWAKTHRKDTQGVGNLIDSKIRYLQNGQTNGIPQGNVLMD
                     FVAEIVLGYADKMLLNKIEKTEIKEFKILRYRDDYRIFSVRKDQAEVIIRLLSEVLSD
                     LNLKLNSNKTFLSDNIILDAIKPDKIYWDLKHASFTEKSNNKWKFKLSLQKHLLQVKL
                     LGDKYPNCGSLSKALSEVYTHRVSTLNKRPDDIYQLISILVNIMQKNPRTLEACIVIL
                     G"
     gene            complement(1352..1597)
                     /locus_tag="LY912_002803"
     CDS             complement(1352..1597)
                     /locus_tag="LY912_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956412.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRIRLEKGIGQTELIRDLQLHKIA
                     ITRETLVKIEGGRQHIKLDQLRAIRDILQVSYEDLLQ"
     gene            1702..2475
                     /locus_tag="LY912_002804"
     CDS             1702..2475
                     /locus_tag="LY912_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956413.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSETSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAKLYTEKVEQFFKSGANKDFSKISDYSENFFNETQDEIMNSTFMA
                     EDMYNMTLKKIKAYDHPLNLTLNNGLLSFVLAGYVDYEYSPDYLEKPLQHENNDINFR
                     FVYESKSKTWLVDQLSTINTSFHELPKPENEVEMVIKIF"
     gene            complement(2705..2953)
                     /locus_tag="LY912_002805"
     CDS             complement(2705..2953)
                     /locus_tag="LY912_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBM6956414.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDLMKNEKEDDFKVV"
     gene            complement(3052..3402)
                     /locus_tag="LY912_002806"
     CDS             complement(3052..3402)
                     /locus_tag="LY912_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956415.1"
                     /translation="MIFENESEEIGRMTEENKVDLLETLVINKKEFEQLFLDFFVQYD
                     RIYDFNSSLDLFELEAEIIENSREKNGKIIISVEKFNELFSETFEIDADYYQPQEVFR
                     EFRNKIIGFSQTTK"
     gene            complement(3443..3937)
                     /locus_tag="LY912_002807"
     CDS             complement(3443..3937)
                     /locus_tag="LY912_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956416.1"
                     /translation="MFKVYFPFQWLVKGIFFVLLGLILFGSYLTIKARYFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIELTEKRNEFAQHDRVLQVTYTMKNDTENPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESGKSETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFNL"
     gene            complement(3930..4232)
                     /locus_tag="LY912_002808"
     CDS             complement(3930..4232)
                     /locus_tag="LY912_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956417.1"
                     /translation="MSDPYIKVYCSKETKKLFDSFYEKNKGTLGTKANMFRVMVSNLP
                     MLASQSNKKFSDPESIKLEQTISELESSIMKKLDGIDQKLSCSLKTKYKTEEKKDV"
     gene            complement(4255..>4598)
                     /locus_tag="LY912_002809"
     CDS             complement(4255..>4598)
                     /locus_tag="LY912_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="HBM6956418.1"
                     /translation="DVFGENKNQFFGFAVEEEPLKYKKKCVNLVYKKVVYDIAESLST
                     DYDQFNIQDTEPALKRNFKKRYIQETKRVLYLFNRAIDDGTIEKARREYEETARGIDY
                     QKQQNQYDMDF"
BASE COUNT         1472 a          854 c          586 g         1686 t
ORIGIN      
        1 tacctaaaat cacaatacaa gcctccaaag ttctaggatt cttttgcatt atattaacaa
       61 gaatactaat caattggtag atatcatctg gtcttttgtt taaagtagaa actctatgtg
      121 tatagacttc acttagcgct ttacttaaac tcccgcaatt tggatatttg tctcctaaaa
      181 gctttacctg tagcaaatgc ttttgaaggc taagcttaaa cttccactta ttattacttt
      241 tctctgtaaa acttgcatgt ttaagatccc agtaaatttt atcaggctta attgcatcta
      301 aaattatatt atccgataag aatgttttat ttgaatttag cttcaaattt agatccgata
      361 atacttcaga taacaatctg ataatcactt cagcttgatc ttttcgaacc gaaaaaattc
      421 tataatcatc tctgtaacga agtattttga actctttaat ctctgttttt tctatcttgt
      481 tcagtaacat tttatcagca tacccaagta ctatttcagc tacaaaatcc atcaatacat
      541 ttccttgagg tataccgttc gtttgtccat tttgtaaata tcgtatttta gaatctatta
      601 agtttccaac gccttgagta tcttttctat gtgtcttagc ccattctttt gaatgtactg
      661 cccacgggat agtatgtgtg tacattgagc tataacaatc ggtaatatct gaatgaatgc
      721 agtagtcata ctccaaagca taactaatct gtgcttgttc aaggttctcc caccaattta
      781 aaatagtttc cgcagtatcg ctctttgaag aaatagattc cacaggaagt gatatacatt
      841 caattcgctt gtcggcttgg aattcttcaa acttattttt gatgtgattc caattatttt
      901 tctgtgtaat cccgtttact aagtctacat atactaatgg atgtaatatt tgaaggggtc
      961 tccaagcata attaccatct ttattagcta atattcgatg attaacatca actgcctcag
     1021 agagcgatct cttatgtcta actagttcag taaatgattt gttttttaat aaatccactg
     1081 ctttctcaat gcctactgat aaatcaatat aattgggcaa cgatgtacta aaaaaacttg
     1141 atgtttttaa aaagaattgc tttgcttctt gatgattcat ctctaaaata ctttttctag
     1201 tcctagtcaa attcaaaatc tcctagatca attaagttgt aatgtaagag gataccctaa
     1261 cgttacatat ctcattcatt attataccag tatttcttca tgacacataa gggtgtaaca
     1321 taataatttt aaacgaaatg actacaagta gtcattgaag taagtcttca taagatacct
     1381 gtaggatatc cctaattgct ctcaattgat ctaacttaat gtgttgccgg ccaccttcaa
     1441 ttttaaccaa tgtttcccta gttatagcaa ttttatgaag ctgtaggtct ctaatcagct
     1501 cggtttgacc aattcctttt tctaatcgga ttcgtctaat attgctaccg attacatttt
     1561 ctttatcaat aattttttcc tctttcaaga atagcacacc ttttggacta aaattagtcc
     1621 tttttcttat taatcttaaa gattcggtat gctacaatgg gactagtatt agtccacatt
     1681 caattttaag gaggaatttt tttgaagaaa tttgcaatca ttctaacctg cgctttactc
     1741 atcggaacta taagcgggtg taccacttct gaaacaagtt ctacaagtac ggaaactagt
     1801 acaacaacct cagaaaagaa ttacccaata catttttttc cggttccaga tggatttgaa
     1861 gcttattatc atgataaaaa actagatgtc cctttatcag aaactgaatc tactgaaaag
     1921 attttgccaa ttgaaattga aagaaatcaa gacgatataa aactaaaagc tgatcttccc
     1981 ttactgaaca gcacacaaat tgatagacat gaaaatatta aagttaatat tgaaaaagga
     2041 gcgttagcaa aactttatac tgaaaaagtt gaacaatttt ttaagtctgg tgccaataaa
     2101 gacttttcaa aaataagcga ttattcggag aactttttta atgaaaccca agatgaaatc
     2161 atgaactcaa cttttatggc tgaagatatg tacaatatga cattaaaaaa aataaaagct
     2221 tacgaccatc cgttaaatct gacactaaat aatggactgc tttcttttgt attagcaggt
     2281 tacgttgact atgaatattc accagattat ttggagaaac ctcttcaaca cgagaacaat
     2341 gatattaatt ttagatttgt ctacgagtca aaaagtaaaa catggttagt tgatcaatta
     2401 agcacgataa acacaagctt ccatgaatta cctaaacctg aaaatgaagt tgagatggtc
     2461 attaaaatct tctaaaaaag aagcgttgaa ggagaaatat tcctttcaac gctctttttt
     2521 atatgcttag aaacataaat aaattgtata ctttcttttt agcccctatt acttttcacg
     2581 aaaaatatct ttttttcgac gctagcgttt ctctacttct aatactgtac acagtttttg
     2641 tattattgaa aaattactca ttatttagca ttaatccaca tcgttttatc aatcgacctt
     2701 catactaaac tactttaaag tcatcttcct tctcgttttt cattaaatca gacacataag
     2761 cccatgtacc cgttcgttgt aaataaagtt cttcttgtaa caactcccat tttctcttag
     2821 aaatcataat gacgccatcg ttcaatccat ttttagaatc cctagtaatt tctatttcag
     2881 aatttgaatg aactacttct tgcaacactt tacctatatt ttctttgaag tttgttggag
     2941 taatagtatc caaaatgaac acctctcttc tctatacctc tattatgaag cgcccatcaa
     3001 ataaagcaag cgttgaggaa taattctatc aacacttgct ttattaagct ttcattttgt
     3061 agtttgacta aaaccaataa tcttatttct aaactctcga aaaacttctt gtggctgata
     3121 atagtctgca tctatttcaa atgtttctga gaataattca ttgaattttt ctactgaaat
     3181 aatgatttta ccattcttct ctcgactgtt ttctattatt tctgcttcta attcaaataa
     3241 atctagtgac gaattaaaat cataaatcct gtcatattga acaaaaaaat caagaaaaag
     3301 ttgctcaaac tctttcttat ttatcactag tgtttcaagc agatcaactt tattttcttc
     3361 agtcattctt ccaatttcct cactttcgtt ttcaaaaatc acaaaaatga tattaactta
     3421 aaagccacta acaaaataag acttacaaat taaagggtaa tccaacaaaa taaccattcg
     3481 ctctacgtac tacgatttgg tagtcctgcc tttcaatcgg taattcataa tagtaattta
     3541 ctgtttctga tttaccactt tcaatatact caggattatc caatatcata gcatactcat
     3601 aaagctcttc accatcctta ttttcaatcg accattgttg cggacgtatc ggattttctg
     3661 tatcattttt cattgtatag gtcacttgta atacacgatc atgctgtgca aattcatttc
     3721 ttttttcggt cagttcaata tttttaaatg ttagttcaac cccatctgcc tgataagttt
     3781 cacctatttt taaatctttt gttacaattt ttattggctt ttcttctgga aaatacctgg
     3841 ctttaattgt tagataactt ccaaaaagaa tcaatcctag tagcacaaaa aaaattcctt
     3901 taacgagcca ctgaaacggg aagtaaactt taaacatctt ttttctcctc cgttttgtat
     3961 ttggttttta gagaacacga taacttttga tcaataccat ccaacttttt cattatactt
     4021 gattctagtt ctgaaattgt ttgttcaagt ttaatgcttt caggatcact aaatttttta
     4081 tttgattgac tagccaacat tggtaaattt gaaaccatca cacggaacat atttgctttc
     4141 gttccaagag ttcctttatt cttctcataa aagctgtcaa acaatttttt tgtttccttt
     4201 gaacaatata ctttaatata cggatcagac attcttttcc ctctccctgt ttacttaaaa
     4261 atccatatca tattgatttt gttgtttttg ataatcaatt cctcttgctg tttcttcata
     4321 ctctctccga gctttttcaa tcgtaccatc atcaattgca cgattaaata aataaagaac
     4381 acgttttgtt tcttgaatat aacgcttctt aaaattacgt tttaaagcgg gttcagtatc
     4441 ttgaatgtta aattggtcat aatcagttga taaactctct gcgatatcat aaacaacttt
     4501 tttatacacc aaatttacac atttcttctt atattttaaa ggttcctctt ccactgcaaa
     4561 tccaaagaat tggtttttat tctcaccaaa aacatcca
//
LOCUS       DAFKHN010000143         4466 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFKHN010000143 DAFKHN010000000
VERSION     DAFKHN010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.146"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            575..1009
                     /locus_tag="LY912_002810"
     CDS             575..1009
                     /locus_tag="LY912_002810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956419.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2299..3222
                     /locus_tag="LY912_002811"
     CDS             2299..3222
                     /locus_tag="LY912_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBM6956420.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3238..3777
                     /locus_tag="LY912_002812"
     CDS             3238..3777
                     /locus_tag="LY912_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBM6956421.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1672 a          670 c          754 g         1370 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacggagaa cttaaattaa attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagagacg gataaataat aaaaaagact
      181 gctctttcga gcagccagtt aaaaaaataa tgagagttta ttcttgaaaa agcaacgcgc
      241 ttataaagcg ctaccaaaat tttatcatat tttataaaaa ataacaatcc agtaaaaaat
      301 gactggtaaa aattcacaaa gaaacggaaa gaagcaacta cagaaaatca agccttaaaa
      361 agagcttttt acctagacca attaaaaatc acaaagtgag cgtctctatc cattggtaga
      421 ggggcaactt ggtctagtcg acattatgtc tactaacctt taaaataaca cgttttataa
      481 aataaaccct cttgacaata tttaattttc tgattattct aaatatatac agaaagcgct
      541 ttcctaggat tttatatcta aggaggaagt aacaatgaaa aataaaatta ttaaaattat
      601 tacttgtcta tttttgttcg gtatgattgt tggagcaagt actccgttaa atctgtttcc
      661 ttttagtgct agaggtataa aagtggaagc tgcaagttca cgatataatc ataatcatcg
      721 tggatttact tgctataaaa tgaactatta tgttactaat aaaatgtgta gagatttgaa
      781 aaaaaattat aataagctaa agactcctgc tcaaattgca tcttttattc ctattggtgg
      841 agttggaaca tgggttatta caaatgcttt tagtagtgct gttgatgcaa tgaatgtctt
      901 tgtaagagct gcaaatcaag gaaaaggtgt acaattaaca tataatgctc actttagcaa
      961 tacaacatca tatcaataca atgattacgc tcgttatgta ataaaataat cagaaagtga
     1021 aactatctca tgaataaaaa gattttagct gtaattattt caataatagt tttaatcact
     1081 atgttcttca tatttaggct aattttcaat ataagcttac aaaaaagtat tctttatcta
     1141 attcctatag catttatctt agcaattttt agaagtattt acggaaataa aaactctaaa
     1201 tagctaaaaa taaatcatac taaattttac aaaaagtggc tagcattttc tagccacttt
     1261 ttgtattgtg gagcgtgggt tttgaggggg attcaagggg gagcttgcgc ccctttgaca
     1321 agcggttatt tgcaccaaat acggaggtat ttggctagca aatatagagc ttgccaaacc
     1381 cttttagtga gttttgtaga aagtaccttt aaaggtactt tcacattacg aacgatacgt
     1441 ccgtaggacg tactgaaagg gtgggactta tgagcaaatt aatgcaaaat ttggctagca
     1501 aaaaagctaa aaaatatatg ctaataatcg agcgaaataa acactttttc aagtgagcga
     1561 atccgccatg acaaagctga agcagtttat ttcagctttg tcatggcgtg tgccgacttt
     1621 tttaaaagtc taggcacacg agcaaatatc tttatcaagc tctaatttgc gttttaagac
     1681 gtttgaaacg cctaagtata taaatatata agaataggtt taagagtgct taaatcgaat
     1741 tttagagggc atttagacaa ttttagggtt gttagggctt gccctgaccg cctgtaaggc
     1801 gttttaagaa caagataagg gatttatact aggactgtct taaaatgtct taaacgaacg
     1861 ctcagagctt ctcaaagggt tccttatgaa cggcttttag caaaggagcc ggaggcgact
     1921 gcgcagtata atgtgagagc agagcgatca caccttttta gcgaaccgta gggagcaagg
     1981 tttggaattg gcagttttga taaattcgcg aacctgttta gagaaaaaag gagtgatttt
     2041 ttaggcggga aaattagcct cccctctttt tatatctctt tttatatctc tttttatatc
     2101 tcttttatgt cggctgtgtc cttactctcc caagcaattc agagtttttt caagtaggtt
     2161 ttctacgctt ttcaagtagg ttttctacgc ttttcaagta ggttttctac gcttttcaag
     2221 taggttttcc gacattattg agtattttta taaagtatgt tacttttatt tcatacttta
     2281 taaaagtagg agaagcttat ggcaaatgaa attgtaaaat atgaaaatag attaaatcat
     2341 attcctctga gaaaatttaa tagtcgtgaa atgaacttat ttttttcaat tgcttcacgt
     2401 gtacgtgaaa aaggtgtaga tgagattatt ttttcatttc acgatttgaa aaaactaagc
     2461 ggttatacag aacgtgggga acaatttata aaagatctta gtagcacgta tgacaaatta
     2521 ttaagtatta atgcttggaa tgatgatgga aatactttaa ctaaatttgt tgctttcaca
     2581 aaatatagca ttatacgaga taaacaactt gttataattt cagttaatcc agaatttaaa
     2641 ggacttttta atcaattaaa gaactggaca agatttaatc tagagcaatt tactaatttg
     2701 gatagcacat attcaaaaac tatgtttcga ttattaaaac aatatcgaac tcaaggctgg
     2761 actgaatttt ccaaagaaaa attttttgat ttactagata ttcctaaaag ttattggaat
     2821 agtccgtcaa atattgacaa atttatctta aggccaatta aagaagaact cactccctta
     2881 tttaaaggat taactattcg taaaaaatat ggtaaaggtc gaggtaaacc tgttatcggt
     2941 tatcgtttta cttggaaagc tgaaattaac catgctgacg atttttccaa agggaaacaa
     3001 gaagatttac gtataaaatt atttaatatt gatcacaatg gagaattaac acgagaagaa
     3061 aaatggcgcg ctaaagatcg aatactaaat cttcccttag gcactcatga agctgatttt
     3121 aaacaacaac aacaaactga agaaaaacag gcagaaaaac gagaactttc aaacaaactc
     3181 aaacaagatt tactaggaaa tttacaaaac ttattcgatt aagcttaagg agtatttatg
     3241 gcagataaaa caatcaaaga acttgcggaa gaattaggag ttagtaaaac agcaattaac
     3301 aaaaaagttt ctgacaaaaa tcgaaaactt tggtttgcaa aaaacggaaa caagtttgtg
     3361 attaacgaaa ccggtcaaaa agctataaaa tcaatgtttt tagtcgataa cgcaaactta
     3421 aatcgaaaac tagttggcga aaaatcaaaa accaaaaacc ataaaaacac caaccaagtt
     3481 tccgaattaa aactcctttc tttcctagaa aaacagttaa atcgaaaaga tatacagcta
     3541 caagaaaaag ataatcaaat aaaacaaatg caaaaattac tcgaccagca acaacaactc
     3601 actctacaag cgaaccaaca aattgagaac ctacaagaac agctccattt aacttataca
     3661 gaagaaactc caacaaccga atcaactgcc ttttctgaaa aaaaagcaga caatacacaa
     3721 ccacttattg aaaaaaagtg gtggcaaatt tggaaatcta atagaaccaa tctctaaaat
     3781 tttctagaag ttagttcgga tagtagagga aaaagttgta ctacctgatg gggagatcac
     3841 tcaaattttt atgagaaaga aaaaatagtt tacaactgta aacaatcaat gtttatagtt
     3901 gtaaactatc aaactatatg gtgacttatt gcttaaaata ggttgaaatc tcactcaatt
     3961 tttggtggaa aaacaaaata aattctaatc gattttgttg aaaaagtcat aaaaaaacaa
     4021 atgtgatttt aacaaaattt caaaaaaatc gtttgaaatt tcgtttattt tttttgagaa
     4081 ttttgatcat cgtagggtca ttgtagaatc attatgagat catcgtggga tcatcgaata
     4141 aagtatggga aaggcttgcg gtgcttggta ttaagggcat tctccgcctc ccaggttctt
     4201 gaccattttc tctcaacgtg gtaaaaatcc cacttataag agaaaatggt caagaaccta
     4261 aacggtcggc gaagaaaaca taccaagcac cacaagcaaa aaaagttaga gtaacttcca
     4321 aaaaagaaaa attttttaga acaacttttg aaaatttaat tttgatttat atccgttcaa
     4381 tttaaacatt tgataaactg aaggctagta tttaaaatgt gtatacaagt ggtagcgtta
     4441 aaaaaagtgg aggtataacc tatgtt
//
LOCUS       DAFKHN010000144         4406 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFKHN010000144 DAFKHN010000000
VERSION     DAFKHN010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.148"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..329)
                     /locus_tag="LY912_002813"
     CDS             complement(<1..329)
                     /locus_tag="LY912_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBM6956422.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSS"
     gene            complement(459..1043)
                     /locus_tag="LY912_002814"
     CDS             complement(459..1043)
                     /locus_tag="LY912_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBM6956423.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(1374..1607)
                     /locus_tag="LY912_002815"
     CDS             complement(1374..1607)
                     /locus_tag="LY912_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBM6956424.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(1622..2572)
                     /locus_tag="LY912_002816"
     CDS             complement(1622..2572)
                     /locus_tag="LY912_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBM6956425.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(2569..3411)
                     /locus_tag="LY912_002817"
     CDS             complement(2569..3411)
                     /locus_tag="LY912_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBM6956426.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(3413..4132)
                     /locus_tag="LY912_002818"
     CDS             complement(3413..4132)
                     /locus_tag="LY912_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBM6956427.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
BASE COUNT         1506 a          798 c          545 g         1557 t
ORIGIN      
        1 gaggataata attcattgct agtatagaca ctaaccaaca accatgagat cattacgacc
       61 ggcaacattc gaaatacaat atataaggat gtcgcaaaaa atatagtaaa aaactctatc
      121 ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa gatgaaataa
      181 atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat gaaacacccc
      241 acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat atttaaagta
      301 atcaaggtta acggattgat ttttgacact ctttcacctc caaaaaataa gatcgcactg
      361 ttatcttaag ctgataaaaa tgcaccgtta ttcagataac agtgcgatct tatcaaaaag
      421 cataactgag aacaattctc aatgcaagct ttttttaatt aactcagtaa ttcaatccac
      481 ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc ttttgaatag
      541 ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa gtggatttct
      601 tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt atctagacaa
      661 cagactgtct ttttcgtcac aaatgatgta attttttcaa caatatcttg atatttggtt
      721 ccagctgatt ggaataaaat caaatcgaat atacgtttat tctcaaaaat ataattaata
      781 aatggatcta attcattgaa gttctctctc caacttttct ctatatctat attttctaag
      841 tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt aatatgcggc
      901 tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa agcacccgta
      961 gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc ttctttttca
     1021 aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc tctggtttct
     1081 atgggtactt cctcctaata agatgaatta actttattat cttacacagg acttgaagtt
     1141 tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg agaaagagca
     1201 gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa atcattcacc
     1261 ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta ggataagtcc
     1321 tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt cttttactta
     1381 aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg aaatcctata
     1441 tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc tggactaaca
     1501 cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga taattcctga
     1561 attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc taccctccaa
     1621 attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc gcatagtaac
     1681 tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa tagataggaa
     1741 tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt tctacgaata
     1801 aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga tctggtgttc
     1861 cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac gctttcgaga
     1921 aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga attgaagcaa
     1981 atttagattt agcttctttg tctagagaat ccaatttttc aatatactta tctagatttt
     2041 ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca atatttttag
     2101 cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc cctttctcac
     2161 tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag tctttgtttt
     2221 cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca gtttccaagt
     2281 taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct tcaggcaaag
     2341 gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca attttatctt
     2401 ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact tttaattttt
     2461 cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg aatataaaaa
     2521 gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc ataacgatct
     2581 ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta caaataagaa
     2641 tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac caataaacaa
     2701 tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag ttttcaagct
     2761 atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa ttaatatagt
     2821 tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca atagataatg
     2881 ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag aagtgattaa
     2941 taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc caattgtaat
     3001 ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa ataaatccgt
     3061 tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac tgaaagtaat
     3121 accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa taatgataga
     3181 agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa tataagaaat
     3241 tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca ttcctcttaa
     3301 aataataaaa caacctactg ttccagaaac aatccctata actacagatg taattagagc
     3361 attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca tattattccc
     3421 cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca ttaaatacag
     3481 attctacact tccgtgagca attagatttc gattcaaaag aataatatta tcaaaatact
     3541 tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga tgtttcaatt
     3601 tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca aatggttcat
     3661 ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca cgttgaaatt
     3721 gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg accttttcca
     3781 aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact ttcattccgg
     3841 catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa tcaatatcag
     3901 ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca ttattaatgg
     3961 agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg gattttccag
     4021 caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa gaaatctcgt
     4081 tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac ataactttct
     4141 ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata ttttagtcaa
     4201 ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga caaaactatt
     4261 tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg ttctcaaatg
     4321 agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg aagtggatag
     4381 cgggttgaat aagttgataa gcatca
//
LOCUS       DAFKHN010000145         4381 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFKHN010000145 DAFKHN010000000
VERSION     DAFKHN010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.149"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..1657)
                     /locus_tag="LY912_002819"
     CDS             complement(<1..1657)
                     /locus_tag="LY912_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /protein_id="HBM6956428.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKL"
     gene            1803..2378
                     /locus_tag="LY912_002820"
     CDS             1803..2378
                     /locus_tag="LY912_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956429.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            2592..3287
                     /gene="vanR"
                     /locus_tag="LY912_002821"
     CDS             2592..3287
                     /gene="vanR"
                     /locus_tag="LY912_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBM6956430.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            3265..>4381
                     /locus_tag="LY912_002822"
     CDS             3265..>4381
                     /locus_tag="LY912_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBM6956431.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVEL"
BASE COUNT         1402 a          826 c          842 g         1311 t
ORIGIN      
        1 atagctttcc tttttcaaga gaaaccccat ctaacttatt ggaattggca gctaaccact
       61 ttaacctttc attaaagctg ctggttctct ccgttatata atcttcgaat gataaactaa
      121 ctgataatct cgtattcccc ttcgattgat tccatgtatc ttccgaaaac aaatattcct
      181 caaaatccct atattgtctg ctgccaacaa tggaaacatc tcctgcccga acatgctccc
      241 gaagttctgt taaaacagcc atttcatagt aatgacgatt aattgttgta ccatcatcct
      301 cgtataaatg tcttttccat cgttttgaaa taaaatccac aggtgagtca tcaggcactt
      361 ttcgctttcc agattcgttc attcctcgga taatctcaac agcttgtaaa agtggctcat
      421 ttgcctttgt agaatgaaat tccaatactc ttaatagcgt tggcgtatat tttcttagtg
      481 aataaaaccg tttttgcagt aagtctaaat aatcatagtc ggcaggacgt gcaagttcct
      541 gagcctcttc tactgaagag acaaaggtat tccattcaat aaccgattct aaaaccttaa
      601 aaacgtctaa tttttcctct cttgctttaa ttaatgcttg tccgatgttc gtaaagtgta
      661 taactttctc atttagcttt ttaccgtttt gtttctggat ttcctcttga gccttacgac
      721 cttttgataa caaactaagt atttgcctat catgaatttc aaacgcttta tccgttagct
      781 cctgagtaag ttgtaataaa tagatggtta atatcgaata acgtttattt tcttgaaagt
      841 cacggaatgc atacggctcg tatcttgagc ctaagcgaga cagctgcaac aggcggttac
      901 ggtgcaaatg actaatttgc actgtttcta aatccattcc tcgtatgtat tcgagtcgtt
      961 ctattatttt tagaaaagtt tcgggtgaag gatgacccgg tggctctttt aaccaaccca
     1021 atatcgtttt attggattcg gatggatgct gcgaggtaat aatcccttca agcttttctt
     1081 tttgctcatt tgttagagat ttactaaccg tattaaatag cttcttttca gccattgccc
     1141 ttgcttccca caccattctt tcaagtgtag tgatagcagg cagtataatt ttgttttttc
     1201 ttagaaaatc tatgcattca tgcagtagat gaatggcatc accattttcc aaagctaatt
     1261 gatgaaggta cttaaatgtc attcgatatt cactcagggt aaaagttaca aagtcgtatt
     1321 cacttcgaat ttctttcaaa tgatcccaaa gtgtattttc cctttgagga taatgatcaa
     1381 gcgaggatgg actaacacca atctgtttcg atatatattg tatgaccgaa tctgggatgc
     1441 ttttgatatg agtgtatggc caaccgggat accgaagaac agctaattga acagcaaatc
     1501 ctaaacggtt ttcttccctc cttcgcttat taactatttc taaatcccgt ttggaaaaag
     1561 tgaagtaggt ccccagtatc cattcatctt cagggatttg cataaaagcc tgtctctgtt
     1621 ccggtgtaag caattctcta cctctcgcaa ttttcattca gtatcattcc atttctgtat
     1681 tttcaattta ttagttcaat tatatatcaa tagagtgtac tctattgata caaatgtagt
     1741 agactgataa aatcatagtt aagagcgtct cataagactt gtctcaaaaa tgaggtgata
     1801 ttttgcggaa aatcggttat attcgtgtca gttcgactaa ccagaatcct tcaagacaat
     1861 ttcagcagtt gaacgagatc ggaatggata ttatatatga agagaaagtt tcaggagcaa
     1921 caaaggatcg cgagcaactt caaaaagtgt tagacgattt acaggaagat gacatcattt
     1981 atgttacaga cttaactcga atcactcgta gtacacaaga tctatttgaa ttaatcgata
     2041 acatacgaga taaaaaggca agtttaaaat cactaaaaga tacatggctt gatttatcag
     2101 aagataatcc atacagccaa ttcttaatta ctgtaatggc tggtgttaac caattagagc
     2161 gagatcttat tcggatgaga caacgtgaag ggattgaatt ggctaagaaa gaaggaaagt
     2221 ttaaaggtcg attaaagaag tatcataaaa atcacgcagg aatgaattat gcggtaaagc
     2281 tatataaaga aggaaatatg actgtaaatc aaatttgtga aattactaat gtatctaggg
     2341 cttcattata caggaaatta tcagaagtga ataattagcc attctgtatt ccgctaatgg
     2401 gcaatatttt taaagaagaa aaggaaacta taaaatatta acagcctcct agcgatgccg
     2461 aaaagccctt tgataaaaaa agaatcatca tcttaagaaa ttcttagtca tttattatgt
     2521 aaatgcttat aaattcggcc ctataatctg ataaattatt aagggcaaac ttatgtgaaa
     2581 gggtgataac tatgagcgat aaaatactta ttgtggatga tgaacatgaa attgccgatt
     2641 tggttgaatt atacttaaaa aacgagaatt atacggtttt caaatactat accgccaaag
     2701 aagcattgga atgtatagac aagtctgaga ttgaccttgc catattggac atcatgcttc
     2761 ccggcacaag cggccttact atctgtcaaa aaataaggga caagcacacc tatccgatta
     2821 tcatgctgac cgggaaagat acagaggtag ataaaattac agggttaaca atcggcgcgg
     2881 atgattatat aacgaagccc tttcgcccac tggagttaat tgctcgggta aaggcccagt
     2941 tgcgccgata caaaaaattc agtggagtaa aggagcagaa cgaaaatgtt atcgtccact
     3001 ccggccttgt cattaatgtt aacacccatg agtgttatct gaacgagaag cagttatccc
     3061 ttactcccac cgagttttca atactgcgaa tcctctgtga aaacaagggg aatgtggtta
     3121 gctccgagct gctatttcat gagatatggg gcgacgaata tttcagcaag agcaacaaca
     3181 ccatcaccgt gcatatccgg catttgcgcg aaaaaatgaa cgacaccatt gataatccga
     3241 aatatataaa aacggtatgg ggggttggtt ataaaattga aaaataaaaa aaacgactat
     3301 tccaaactag aacgaaaact ttacatgtat atcgttgcaa ttgttgtggt agcaattgta
     3361 ttcgtgttgt atattcgttc aatgatccga gggaaacttg gggattggat cttaagtatt
     3421 ttggaaaaca aatatgactt aaatcacctg gacgcgatga aattatatca atattccata
     3481 cggaacaata tagatatctt tatttatgtg gcgattgtca ttagtattct tattctatgt
     3541 cgcgtcatgc tttcaaaatt cgcaaaatac tttgacgaga taaataccgg cattgatgta
     3601 cttattcaga acgaagataa acaaattgag ctttctgcgg aaatggatgt tatggaacaa
     3661 aagctcaaca cattaaaacg gactctggaa aagcgagagc aggatgcaaa gctggccgaa
     3721 caaagaaaaa atgacgttgt tatgtacttg gcgcacgata ttaaaacgcc ccttacatcc
     3781 attatcggtt atttgagcct gcttgacgag gctccagaca tgccggtaga tcaaaaggca
     3841 aagtatgtgc atatcacgtt ggacaaagcg tatcgactcg aacagctaat cgacgagttt
     3901 tttgagatta cacggtataa cctacaaacg ataacgctaa caaaaacgca catagaccta
     3961 tactatatgc tggtgcagat gaccgatgaa ttttatcctc agctttccgc acatggaaaa
     4021 caggcggtta ttcacgcccc cgaggatctg accgtgtccg gcgaccctga taaactcgcg
     4081 agagtcttta acaacatttt gaaaaacgcc gctgcataca gtgaggataa cagcatcatt
     4141 gacattaccg cgggcctctc cggggatgtg gtgtcaatcg aattcaagaa cactggaagc
     4201 atcccaaaag ataagctagc tgccatattt gaaaagttct ataggctgga caatgctcgt
     4261 tcttccgata cgggtggcgc gggacttgga ttggcgattg caaaagaaat tattgttcag
     4321 catggagggc agatttacgc ggaaagcaat gataactata cgacgtttag ggtagagctt
     4381 c
//
LOCUS       DAFKHN010000146         4053 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFKHN010000146 DAFKHN010000000
VERSION     DAFKHN010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.150"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            594..926
                     /locus_tag="LY912_002823"
     CDS             594..926
                     /locus_tag="LY912_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956432.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
     gene            1051..1308
                     /locus_tag="LY912_002824"
     CDS             1051..1308
                     /locus_tag="LY912_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBM6956433.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            1540..1944
                     /locus_tag="LY912_002825"
     CDS             1540..1944
                     /locus_tag="LY912_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBM6956434.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            1963..>4053
                     /locus_tag="LY912_002826"
     CDS             1963..>4053
                     /locus_tag="LY912_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBM6956435.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIE"
BASE COUNT         1488 a          553 c          748 g         1264 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa tacgttatgt agtaaatgta atagtttttt tggtagtgag tatgttgagg
      241 aatatattag atttgcagaa gacaataaaa atttccttta taacaataca agtttaaaga
      301 atggtaagtc tgatttaaca cattcaataa agaaaatgaa ttcacttaga gttgcaaaag
      361 caattgtagg aatgtttttt agtttaaatg gggatgaaga ttcaatggat aagccattct
      421 tagattcggt acgagaatat cttagcaatc ctaaaagtac tttatttcct catgaagact
      481 acaaaattat aatgaattat tatcttccaa taggtgctcc acagaattct aaaatcaaaa
      541 ttcctaatga cattgtaaat gatggtgaca ctcacaatgt aataaaaggt tttctgcccc
      601 ttgatctatc aactgggaga aaaattcgat tttcagaaat tcagtatgaa ggaattggtt
      661 ttactcttat agatttaaaa aattcaactt ttgaaataaa agaaggatta gatttaaaaa
      721 atctcctttg tgcagatgat aaaatcaaaa aaatacaatt gtacaaagtc cctatattaa
      781 caccaacagt acttacaatg ttggagatgg aaaataatat taattatatt gactcaggtt
      841 cagatttgct gattaggtgg caggtaataa ctaattttct tatggaatta aaaaaataca
      901 gtaatactca aacgaagttc tcttgaagtt ataaagaata caataaatat aaatttcctt
      961 tagactatat taaaatcagc aatcgaagga aaataaaaga agaaaatggt acgcaaaatc
     1021 taactattag agcaaaaaca ggaagctgct ttggaagata gtcccgaatt gtttccgatg
     1081 ttaaaagatc gtttaaatga attgactgaa aaacgaagac agttacaaat tcgagagaat
     1141 gaaatcttag ggatctttca acaacaaggg gaaccgattc aagtcaaaga tgtccaacag
     1201 atattgacta gtttggattg ctttcttatc cagagtgaga agaagcaagt taaagctttg
     1261 tatcacacct ttattgagaa aatcaccttt gatcctaatc agaagtagat attgccgatc
     1321 ccgatgagat tcacacctac tgtgatttga taattgaatg agtaatatca aatagccgta
     1381 tccaaaccaa aggatatggc tatttttgtg ttagggatat acgtcacgta gcttgttatc
     1441 aagaataagt ttctttattt ttttgctttt tctaaaactg agtatgctaa aataagaggg
     1501 tatatagcaa ctttaaataa gagataggag tgtatctttt tgggtgcaga attaaatcag
     1561 aagttattta gtgcggcaga taatctccgt agtaaaatgg atgcgtcaga atataaaaat
     1621 tatttattgg ggctgatttt ctataaatat ttatccgacc gtttgttgga acaagtggtt
     1681 cttttagcag atgaatcctt agaggaatat gacacagtaa gcaaacaaac gatgttgtat
     1741 cgtgaattac tttcagatga agaatcaaaa gaagatctga ttgcaacaat cgttgatatt
     1801 ttggggtatg cgatttcgcc agagtatctt ttcaacgtct tagcggatca agcaaaacaa
     1861 gcaacgttcc aattgaatga tctaaacaaa gcctttttag caagtcatat ttatggaaaa
     1921 atactgtcgg caaaattcga atagtgtcga ggaggtgctg tgatggaaga attaaaagaa
     1981 cgcattgtca attatgtcat agagaactct gagattaaaa ataaatgggg gaacaataca
     2041 gcacagaaaa tatctgaaaa attaaatgtt agtcgtaata ttgtctctca atatttgaat
     2101 gaattcgtaa aagatggaga atttggaaaa atcaatactc gtccagtaat cttcttttct
     2161 ttaccggaga aagttccaaa tcaacaaatt tttagctctt cagaggaagc ggaaaaatgg
     2221 tatgatagct cttttagggt tggaatagaa agggttatcg gaagtcaagg aagtctgcga
     2281 aatgtaattg ctcaaattaa agcagcaatc tactatccgc caaatggctt acccatttta
     2341 cttcatggcg agactggaac tggaaaaagc tatttagcaa attatgtgta taaggatttg
     2401 ttggccaata attatataga agagaaggca tctttcattt cagttaattg tagtgaatat
     2461 gccaataatc cagaactttt cttgtccaat ttttttgggc atgtaaaagg tgcatataca
     2521 ggagccgaag atggaagaaa gggtttagca gaattagcta ataatggagt cttattttta
     2581 gatgaaattc atgcattgag caatgaatgt caggagaaac tttttcagtt tatggatacg
     2641 aggaaatttc atcggatggg tgataatgaa aactggtaca catcaagttg ctggattata
     2701 tttgcaacat cagaaccacc tgaggataaa ctattatcaa ctttgttgag aagaatacct
     2761 gtaaagctaa cacttccaac attagacagt cgttctcttt atgaaagaaa acagttaatc
     2821 aagatatttt ttaaatcaga agaagaaaga ctagcaaaga aaatactgat atctcaacaa
     2881 ttattagatt ttttattaaa ctatcgcttt agtgaaaatg ttggcaattt gaaaaatatc
     2941 attcaattga cctgtgccaa tgccttttat ttcttagatg atttggaaga actttatatt
     3001 cagatgtatc atttaccaca atgggtgaat ttcaacggca tgaaggttat gaaaagacag
     3061 aatgaattaa aatatattca aatggatgat ttggaaaaag tagacgaagt ttttaatatc
     3121 aacgaactta tagagtatct ttatcaaacg tggaagaaag acactgataa gcagcagctt
     3181 tttgagaaat atgatagata ttttagacaa aagaatgttg atatccaaaa taattcagct
     3241 ttaacatatc ccacctatca agagattcga tttagacagt atgttaagga aatagagaga
     3301 gattttcaaa tagaatttga ctattattat cttcaaataa cgtctatctt tttgaattct
     3361 tggatttatc aaatccaatt aacatcggac gataaattat attccttcat caatgatatt
     3421 aatagttggt gtagtcgaga agttcaatta gtcaatcgtt ttattcaaat aggggatatt
     3481 tatttaacaa aaattcaaaa aaatgttttg gttattttat ttaagttaat gtgtagtaaa
     3541 gaatttcagc aaaaacgttt agcactgatt ttggctcatg gagatctaac ggcaacctgt
     3601 atagcaagta ctgctaatag gatcgttgag agatatatat acgacgccat tgatatgcca
     3661 ctaatgactt caagtagtga gattgcagac aaaattaata gatacttaca agagtgtacc
     3721 ggatatgaag aaattatttt acttgttgat atgggttcac tggagaaaat ttatctaaat
     3781 ttggaactag acgctcaaaa aaaattcgga ctactaaaca atgtttcaac aagaatggct
     3841 attgatgttg caaatcagat attattagat ttaccgctta aacagattct tgaacaagta
     3901 aaagaaaatc aaaatgtgga ttatatttat gaatcatcaa atattaagaa ggatatgatt
     3961 gtctgttctt gtgcaagcgg attaggaact tcgtttaaat taaaaaagat acttgaagat
     4021 agctttccaa gggatactga tcttgtcata gaa
//
LOCUS       DAFKHN010000147         3889 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFKHN010000147 DAFKHN010000000
VERSION     DAFKHN010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.151"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..316
                     /locus_tag="LY912_002827"
     CDS             <1..316
                     /locus_tag="LY912_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HBM6956436.1"
                     /translation="LTIPGAMSPTEIFKMFEMGADIVKVFPANCLGPEYFNQVQAPLG
                     SLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKSAVHQLNYERLMELAESFIDSLR
                     VE"
     gene            complement(710..1717)
                     /locus_tag="LY912_002828"
     CDS             complement(710..1717)
                     /locus_tag="LY912_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBM6956437.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
     gene            2184..3590
                     /gene="lacG"
                     /locus_tag="LY912_002829"
     CDS             2184..3590
                     /gene="lacG"
                     /locus_tag="LY912_002829"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBM6956438.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            3613..>3889
                     /locus_tag="LY912_002830"
     CDS             3613..>3889
                     /locus_tag="LY912_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBM6956439.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLREL"
BASE COUNT         1282 a          579 c          757 g         1271 t
ORIGIN      
        1 tctaacaatt cctggggcca tgtcgcccac agagatattc aaaatgtttg agatgggtgc
       61 tgatattgtt aaggtgttcc ccgccaactg tcttggaccg gaatatttca atcaagtgca
      121 agccccttta ggaagtttac ctttgatggc tgtaggaggg gtagatcaga ctaatgcaca
      181 aaactatttg aacaatggag cctcttatgt aggaattggt tcaaaatttt ttgaaaaaag
      241 tgctgttcac caactaaatt acgagaggct aatggagttg gctgaatctt ttatagatag
      301 tttaagagtt gaatagaacc catttgcgga atacaacttg ttttataata tggcgttatc
      361 tgtataaaac atagtatcac agtgaatgag attgaactgg tagattgatt tttcgaccag
      421 ttctttttgc gcgctctgat gcttgatata ttcccaacga gataaaaaat cccccaagat
      481 actaagatga agcgtttatc caacctcata cttagataaa aaggaggaaa tgttctgaat
      541 gataaacaaa aattagcgcg cacaatttgg cgatgaaaaa atcatattgt atttacgtca
      601 aaatatcacc atcaaattat ttatggaaaa cataataggc ataaacccga ttgctcggct
      661 actatgtgga cacaattata gttttaaaga taagtttcaa ttacttattt tacacctctt
      721 ctttagggat aaaacttttc ctaacggtca attttgcgcc gattaatgtt ttctttgata
      781 tgtcccgcga atataccagt tgatcactta ataaatctac acaggtttta gctatctctt
      841 cgatatctat cttaaaagtt gtaagtggtg gtgcaacgaa ttttgcgatg tcgtcatcat
      901 taatacttat tactgccata tctttaggga tgttaatacc caattcatgg cagccctgaa
      961 gaacgccggc agctatagtg tcagatggta tgaaacatgc ctcgggcata tcttcattta
     1021 actcagcttt cattttaaga gttaattgat acccttcgtc aacagtaaat gatccttggg
     1081 agaaaatata cttttcattg agtagtccgc tcttttctaa atgatatcgg aaggcatatt
     1141 cacggctatc aatctcttct ttacccgttt ctaggttaaa gaaatttcct ccaataaatc
     1201 caatttttgt gaaaccttca ttaataaagt agttaattgc ttgtctggcc atttcgtgga
     1261 aatcaggttc tacagtatcg aagtgttcag gtaatgggtt tattcctcgg attaccccct
     1321 tatacccttt ttgatttaag tagtacaatt ccttttttgt caattgtcct attgcgataa
     1381 atccagtaat atcgtcagga atgcttttta caccatcgtt tttagagatg aaaatcaaat
     1441 ctagattagc ttttttacta taatttttca aatcatcttt gacatgttga tagtagacat
     1501 ccttttttaa ctgttcctct gagatccaaa aaagaatggc aatcttgtac agagtagtct
     1561 taatttttgt cagatcatat cctaaagatt tggctgtaac gattattttg tttttagtat
     1621 cagatgtaat agagagtgac tcatcacctt taaaaagtct tgatatagta gccgttgagt
     1681 aaccagattt ttttgcaata tctctaatag taaccattgt tcatcctcct agggatataa
     1741 taatcctttt ctttgttaaa gtaaatcgaa actgctcttt tagtaactta aattactttt
     1801 tctagcagga aacgaaactc tgatatcagc agagagccta atccattaac agagaagatt
     1861 gaatcgataa tggatagcca cttggagaat gattagtagg tgggattgat tttagtggga
     1921 atcagtccgt tttcttgttt cgtgtaaatt aaattagtaa aaagataaat ttattttaca
     1981 aaaaaacgtt tacaaaacgg tttttgaatg gtatatttat tttacatcaa gggatataag
     2041 tgcttgtata tcgcaataaa atagatattc gaggtcggtt tttcgttgtg taaaaaaatt
     2101 tacttataca tgttaaaatt atgctgaggt gatttatggg ttattggcat attgatcaaa
     2161 ctaattttca aggagagatt aaaatgaatt ataaaacttt accagaagac tttattatgg
     2221 gaggagctac ggcagcttat caagcagaag gctctacaaa agaaggtgga aaagggcaag
     2281 tagcgtggga tactttcctt gtagaaaagg gacgctatac tgctgatcca gctagtgatt
     2341 tttataatca atatccagtt gatgctgaat tatgcaaaaa atttaaaatt gatagtatta
     2401 ggatgtctat tgcatggagc cgtatttttc caaaaggcta tggggaagtg aaccaaacag
     2461 gagtggaata ttatcataag gtatttgctg aattgaataa gcatggtatt attccttttg
     2521 taactcttca tcattttgat acccctaaag aactatttga taatggagat tttttaaatc
     2581 gagaaaatgt tgaacatttc gtaaactatg cacagttctg tttcgatgaa ttttctgagg
     2641 ttcattattg gagtacattt aatgagattt atccagttgc ttcaaatcaa tatttgatcg
     2701 gatcgtttcc tccagaagtt caatttgata tagagaagac tgtaacttgt ttacacaaca
     2761 tgatgtatgc gcacgcaaag acagtaaaca tttttaaaga tggtggatat aaaggggaaa
     2821 ttggtgttgt tcactcgcta gagacaaaat atccagcaag tgacaaagaa gaagataagc
     2881 atgctgcgaa attagatgat gcgttatcaa ttaagttctt attagatgct acttatttag
     2941 ggtattactc agatgaaaca atggcacata ttaatgagat tttagcagca aatgggcaat
     3001 ctgcagatat tgattctaat gattttagag agatgaaaaa agcagcaaat cgaaatgatt
     3061 ttcttggtat caataactat ggtagccatt gggttaaaga gtacaaagga gaaagcacac
     3121 ttcactacaa cactaccgga gaaaaaggta gccaagtcta ttgcattaaa gggattggcg
     3181 agagaatcgt gcgtgaggat cttccgaaaa ccgattggga ttggatcatt tatccaaaag
     3241 ggttatatga tttacttgta cgaatccaag acgaatatcc aaattataat aaaatataca
     3301 ttactgaaaa cgggctaggg tataaggata attttgaaga tgggattatt ctagatgatg
     3361 atcgaatcga ttatttacgc cagcatttta atgcgatttc cgatgctatc aaaatgggag
     3421 ttaatgtaaa ggggtatttc atttggtcat taatggatgt tttctcttgg gttaatggat
     3481 acactaagcg ttatggacta ttctatgtag atttcgatac acaaaaaaga tatccgaaag
     3541 agtctgcata ttggtataaa tttgttagcg aaacaaaaac gataatataa aaatagttag
     3601 gagggcaagg aaatggatag gaaagaattg caattattag gatttgaaat tgttgcttat
     3661 gcaggagatg ccagaagttc attattaaca gtgttgaagg aagtgagaga aggtaatttt
     3721 gataatgttg aacgattatt agcggatgct gatgaaaatt taaccttagc gcataactca
     3781 caaacgaaat gtttagctga agaagcgtca gggaacgaaa tggaagtagg cgtaattttt
     3841 attcatgggc aagaccattt aatgacaacg attctattaa gagaactta
//
LOCUS       DAFKHN010000148         3863 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFKHN010000148 DAFKHN010000000
VERSION     DAFKHN010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.152"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(247..468)
                     /locus_tag="LY912_002831"
     CDS             complement(247..468)
                     /locus_tag="LY912_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956440.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(566..811)
                     /locus_tag="LY912_002832"
     CDS             complement(566..811)
                     /locus_tag="LY912_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956441.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1051..1665
                     /locus_tag="LY912_002833"
                     /pseudo
     CDS             1051..1665
                     /locus_tag="LY912_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2035..3036)
                     /locus_tag="LY912_002834"
     CDS             complement(2035..3036)
                     /locus_tag="LY912_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBM6956442.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3195..3461)
                     /locus_tag="LY912_002835"
     CDS             complement(3195..3461)
                     /locus_tag="LY912_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956443.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3451..3807)
                     /locus_tag="LY912_002836"
     CDS             complement(3451..3807)
                     /locus_tag="LY912_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBM6956444.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1222 a          698 c          512 g         1431 t
ORIGIN      
        1 ttttactata tacttcttcc cagaacttgt ccgtctcctt caaattatct ctacctctcg
       61 agttcattgg gtggtttgcc catttattaa acatggaatc acctttctca tactcatata
      121 tttatgtcct atttcaatta tatttatata tgcttaaata aatttgtatc ctgaaattta
      181 ttgtaatatg aagctgtatt ttacatatag taaccaaaga gttaataaaa taaaaagagc
      241 gaaccattat agatcagctc ttttttcatt gctgttttta atcttatcta gaatcacttc
      301 aaatgtttca aaggtattta catctaactg acataaccaa agcaagtact tcttttcttt
      361 gtaagtccaa tcaatattac ggtaagagga cattagatta tggtaccttg ctctttgttc
      421 aactgaagcc aattcccagc gtttttcaaa tattttttct tcttccatta ttgatccctc
      481 gcaagacgct acctcaaact taaataatgg gcagcgaaag tctaattcct tagatctaag
      541 tatagcaaac aaatatgaaa aaaacttaga aggtagtaaa agttcttccg tcttttgctt
      601 tgcttctatt cttaatgtgt ttcgttatcg gtgccctaca aagattttca ttaattacac
      661 actcatttat tgttgtgtat tttctgacat ttctctcttg atcaattatt ttaattccat
      721 gggcatcctg atagttcata ggagaggagc ggctatcaga aatagttgca cctatctctt
      781 gaacttcttt tacaacttct ggaaaatcca tccatcctgc ttcagctgtc aaaagtaata
      841 atctataata tttatctttc cttttcaatc taagaaatcg tcaccccatt ctttttcttc
      901 tattataaac tatttaactt ttagaattca aaaaccgttt gtctatttag agtttaccct
      961 aaatagacaa aaatataaca ttgaaaaatt tagagttcta acgtatgatt agggtgtatt
     1021 ataaacgtta tagaaaagta gggaataaat ttgaaaattg cttatattag agtttcatcc
     1081 atcgatcaaa atgaacaacg tcaaattgaa gaaatgaaaa agtttggcgc tgaaaaaatt
     1141 tttatcgaaa aacaatctgg agcgacgatt agtcatcggc cgattttcca ggaagcttta
     1201 gattttgtca gagagcaaga tatttttatt gtagaagcca ttgatcgact tggacgcaat
     1261 tatgacgaga ttatcgattc agtgaattat ctaaagaaga agaatgtgcg acttattatc
     1321 accagtttac cgatcatggc tgaagcaatt ggaaatcctc tcctagataa attcatcaaa
     1381 gacttaatca tttaaatctc agccatgatt gctgaacaag aacgtactga atcgaaacga
     1441 cgccaggcac aaggaattaa aatcgctaaa gcaaacggcg tctataaagg tcgtcctaag
     1501 ttatacagtg cagacaccaa agatcctcaa cgtcgccttg tctataggag tatcgttcag
     1561 gatcttgaga atggggttgc tatctcaaag attgcaacag actacaatgt gactaggcaa
     1621 acaatttacc gaataaaaaa agaaatcgac caactaattg tatgatttct tttttgaatc
     1681 acgtaattat taattagctt tgtcatcaat acagacaatc attttagatt catctagcta
     1741 agttgattac atttatgtta aaaagaattt agttaacata aatataattg atgcataaat
     1801 cgtccttatt taaaggcatt taacattgac aacttagtat aatgtatctt atgtaaacta
     1861 ataagatttg aattttattt tatacacact cgataataga tcaattttat ggtcccccgc
     1921 atttacgatt gcacaagaga aacataaagt cgacctatta gcatttcttt tcaattcaaa
     1981 cattaaaaaa gtttatacct ctgctactaa aaaatgaaat tatctattta aaatttaaaa
     2041 cggtaaatct gattcatcca aattggaaaa tggatcagcc tgtattggag ctttgtattt
     2101 ctccataata acagatatct ttttttcatt ttttaaaaaa taccttttaa atttcttata
     2161 gtcctctgaa atcaaaatat agcgtgatgg atactcatca aaagaagaat cgtattcttc
     2221 ctttaaaatt cccgatttac ttaatttttc tagtacatca aatactctat cactcaagta
     2281 actccttaaa ttgttatcac tttcccattg aactactttt ctataagttg aattatcagt
     2341 tgaaaagata gaattttcat ccataaacgc atatattagc agcaatcttt catcattgtc
     2401 aaattctatt ggatcaaaaa tatctaagtt gtcatcaaaa tctttatcag ttccggtaac
     2461 ttttttgtta attactgaag gtgtcttgta agaaatagaa tctaaatcaa agcgttttga
     2521 ttctaaatta ttttgtgctt tctcaattaa ataattcact ttttttgtga gaaaccttct
     2581 gatattgtct ttgctatatg ttccataaaa acccttatct tctaaagagt ccctgtactt
     2641 cttaacttct atatactctt cagccaaaac ttgtggaact ggttcatcta agaaaaaaac
     2701 ccctacctcg cctttgctat ttttataaaa gtaatcaatt tctgctatag ttcccgatct
     2761 ataattatca actggagaac ccaacttatg gccaaaaatc gctaataata tatcactatt
     2821 ttctacaatt tgtttattaa taacactttg cccagagcta ttatttatat aagtaggaat
     2881 cgcattcgtt tcccatcgaa ttggcatcaa aattactttt gtattatctg tattttctat
     2941 attccatcta tatatggttt cttctacttc attcctcttt gctgctatat cacctggtga
     3001 tgctataaat acttttatta gatttatggt tttcatttat tgtacctttc tctttatgtc
     3061 tctttaaagt aatttttgta taaaatttat tgacttttac actataggac aacttttatc
     3121 tatttagtac aaaaaggccc actaaactaa ttgattagtt aggagcctat tacaggtata
     3181 ttttcaactc gcttttaagc aaattctact accagctttt tgcctaatgc cctagcgata
     3241 tcatcaagtt tatcgaaaga tacgttatcc cctctctcaa ttcgagcaat agtagattga
     3301 gttgtatgtg ctttttgtgc aagctccgct tgagttaggc ctgcttcctc ccgtgcatga
     3361 taaagagcaa ccgcagtttc gagttttctt ccttcacggt catatgcttc tgcaaaatct
     3421 ttgtcttttt gcttttcttc aatcaatttt ttaatcatca tttgtgaacc actcctctct
     3481 aagttctttt gcatgtttaa gttcacttat tggtgttttc tccgtttttt tagtaaatcc
     3541 atgggtaatg acataccttc cattgaccac atggaaatag atagctcttt ggatgtttga
     3601 tcctacctta cttcttaatt cgtacaaatt agtgtctaat tttttcaccc atttcaaccg
     3661 ttgagctact agcatcccat tcttttctgt ttcttctatt gtacgtaaaa gcttcgcact
     3721 atcttttttt ggtaatgttt ccaaccattc taaaaattca tcatgaccat taggtctttt
     3781 aaatgtttca aaagatattt tttccatacc caattatatc atatattgat tttatattat
     3841 agtatataac ataaaaattc gaa
//
LOCUS       DAFKHN010000149         3718 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFKHN010000149 DAFKHN010000000
VERSION     DAFKHN010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.153"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..2339)
                     /locus_tag="LY912_002837"
     CDS             complement(<1..2339)
                     /locus_tag="LY912_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956445.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATP"
     gene            complement(3011..3279)
                     /locus_tag="LY912_002838"
                     /pseudo
     CDS             complement(3011..3279)
                     /locus_tag="LY912_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT         1057 a          812 c          578 g         1271 t
ORIGIN      
        1 ggtgtcgcat ctaattcata ccctattggc gcttgagttt ctaccagctg atatgctcct
       61 ggtgctaaac cgtcaattgc cagttttcca tcttctcctg tagttaaacc ggtttgtagc
      121 gtttctcctt ctcggttctg taactcaaaa acagctcctt gaaggacttc accactgcct
      181 tcagcatgtt taattagttc aacaccaccc gtatcaagga tgttttcaat ggttaacgtc
      241 acttcttcta tggagtattc atttataaaa acatcatgta ccgtcgcatc taaaagatac
      301 ccttccggtg cttctgtttc tcggacttga tagctaccta caggaagcgg ttcacttaaa
      361 aattctccgt tttctgccgt tataccttct tgtatcactt gtgaatcgct tgataaaatt
      421 tcaaattttg ctcctgccag cctttggcca ttctcatcag ttttaattac tttaatacgc
      481 ccatcgattt tccttgttct tacagtactc gtattcaatc gattgtcact attcacaagc
      541 gttgcaaagt ttaaaatttg atcgccgacc gcatacgcct ctacattgac cttaaaagag
      601 agggtaaaac ttgtcggacc accaatcgta ttattcgcac tgaaacgaac tattccatta
      661 ttgacttcgg catcaatgaa agagggaata tctgatagaa atgacacaaa ttccatgcct
      721 tcttccaaaa catcttcaat aacaagcgta ttgcttgttc cagaaaacat cgagacatgc
      781 agagtatacg ttagttcatt ttcattgaga ttgataacat ttttgtccac actttttctt
      841 aaagagattg ccggaagatt actttcaggg attctcaagc ggtagtctcg gctcattacc
      901 tgattattgt aggtcatact cgctcgattc cgagaaaacc catcctcttg tcttccttca
      961 ttgaacaagt cgacatcggt cacttcaaga gcatattcaa taaaatacga ttgaccctct
     1021 gctagattac caaagtccac aacaagtgta ttcgtttcct tattaaaaga tactttgtcc
     1081 acaaattcct cggaaacata atgagttcta acgtttgctt cacctggatt cgttacttct
     1141 gcgatccgaa ccccacctga aataggttct ctatttccag tggaactcca tgtagtcgga
     1201 ttcggtgcca aagttgttcc ttgcggtagt acatcggtaa ccactacacc gtcttttcgt
     1261 gatccttcat aatttacctg caaaataaat ttattactgt tggtcacgtc ttgcccgtca
     1321 atcagcagat tcccaagatt tccttggctg tcgatttctc tagagccata gtataatttc
     1381 gaaaaaatgg gtcttgatga aggaataggc gtaattgaaa attccgtgtt tgctgctcgc
     1441 tcagcataag taagactcac ttgaaagtca ttatttggct cagtaccgcc tgattgaaag
     1501 aaagcaactt caaacgtgat actgaatgta tacgactgag cggcttcatt taatccttca
     1561 taatcaaagg taaatggaaa aacaacgtct gtgccttctt ggtaaaatgc cagtggcttt
     1621 aaaggtgaat catcagcgac ctccactcta atgaactcaa ttaagccaat cgatgctcta
     1681 ggaactcgta cgaccatctc cccatattct tcaagaatat cgccagcgcc tccttgaatg
     1741 tatcccttta acgtttgtgt atgcctgctc ggcaaagtgg ggcgctcagc agagatgccg
     1801 atgtcataat tcaagagctc ctcttgtctt tcaatctgag attcctgcgt tatagatggc
     1861 tcagatgatc tggcttcatt aaaagattca cttaagcttt cttctggtat attaaaagat
     1921 tcacttgtgc tttcttctgg tacattaaaa gactcacttg tgctttcttc tggtacactg
     1981 atttctattg agaccgtatt tgattgaata tcaccgcttc ttgcggtcaa ttcgtattta
     2041 cctgaatgct gggaagaata agtaatcaga cgttcgtaat cattgagttg cttcacttcc
     2101 ccttcaatca aatcctcact cttatcaatg accaatgcat ttagcaggtc tggtgttcct
     2161 ctgactcgca actggaactg ctcacccaaa gcagcctcct cttgatcaac ttcgatcgtc
     2221 agcgaacgct ctggctgttc tgctaaagac tcagctagaa ccgttatgtt cccaaattga
     2281 ttgatcacaa taagcataac tagaaacata cttaacagtt tatgaaattt gttcctcact
     2341 attactcccc cttataattt tgactaaaca acaaggtacc cgataatttt ctaaaaagat
     2401 tccccaactc aaaatggctg cgttacctcc ctcgtatttt cggttcaact caagcgttgc
     2461 aatgtaagct gtaaacaaag ctaatgattg ccgattgtct tctgttgatt gattcgatag
     2521 ctttgtatga cttttagttg tccgtgtggc ttaaccataa ttatgatttc acgattcctc
     2581 ctgccagtgc cttgcacaag ctggagcgta accctaatag ttattttgtt aatgtactta
     2641 tatactttta tacttttcca ttagaaacaa tcactaaatc gttgatacca aggtcagact
     2701 ctagaatttc atcagtgagt ccctgtattg gttaaccttc atcaatccca aaaaaatata
     2761 tcaatgctta gcatcaaaat gaatatatag tttagaatac ttgggattca tcgataactg
     2821 atcgcttatt tggccatatt atttggcact tggttcaact aaacgcattt aggatgttcc
     2881 ttcattctcg tcatggatgt tctcaaaccg tcattactaa taaactgtcc accgaatcga
     2941 tggttcattt cttgcatttt ccacgtccaa ttactctttt tgctctttat ttgggcgtag
     3001 ttttactttc ttaacttgta tcgtcttcca tcaactcctt aatcatcttc ttagctttat
     3061 tggctcggtt tccttgtaaa aggtatctac aaatagtgac aatctgtatt aaatcttcat
     3121 cattttctgt aatgtcaata atttctatat tctgtaccat atattgcaaa gggtttcact
     3181 aagttcataa ccgaagcgaa ttaaacaact tttgtataga ataactacct tttctatttt
     3241 tccattggta attctatcta ttaattggtt taatcctttt gttgtagttg attccactac
     3301 caagatgatt ctctcgaatt ttaaagcttg aagatgtatt gctatttttg ctaactggcg
     3361 tatttgcaac tatttttccc ttctattctt ccttcattga ttcccctcta aaattactat
     3421 ccataaaaaa ttgcataaat gacaatagta tttatattag tcatactgct ttttaacaca
     3481 gcaaattcca gaaaaacatt cgttacatat ttgtgaattt ttccaaaaaa taacattttt
     3541 ataaaacaac gaaaaataaa tcactaccag tcaacttcta taatattacc aaataacaaa
     3601 ctaactatcc atcaataacg tgttttattt tttaaaattt ctataaaaaa ataatcattc
     3661 ttaaaaagaa tatataaaaa taacaataac ctttgtgatt tttcttgttt gaagaatg
//
LOCUS       DAFKHN010000150         3711 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFKHN010000150 DAFKHN010000000
VERSION     DAFKHN010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.154"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            58..510
                     /locus_tag="LY912_002839"
     CDS             58..510
                     /locus_tag="LY912_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956446.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            524..1213
                     /locus_tag="LY912_002840"
     CDS             524..1213
                     /locus_tag="LY912_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956447.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1338..3689
                     /locus_tag="LY912_002841"
     CDS             1338..3689
                     /locus_tag="LY912_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBM6956448.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
BASE COUNT         1265 a          482 c          772 g         1192 t
ORIGIN      
        1 caattatctt atcgtagata tatattataa atttaataag aaagcgaggt gagaatcgtg
       61 aaaaaaacga tactaagtat tttttcagta tttacaatat taattggggg ctattttctt
      121 ttgaatttag attctgttaa ttcaaacgct caaataaaag atcaaagagt agctgaacat
      181 aataataaaa aaatgagttt gaccaaaaat atctattcta tgtcagatga agaattgtat
      241 aaagaatttg gtgatttatc cggggaacag ttagaagaaa gtattccagg aattagtgac
      301 tcagataaaa ttgttgtctt gtctgctggt gggcaattaa tgggagatgg caaatccgaa
      361 ttagttagtt ataaacaaaa tcacagacag tttattgatg ttaatactga ttccaacgct
      421 atttcgatta aggatctaaa agagctttta aatagtaaaa gaaatgaatt aaagcagata
      481 aaagaaacta attcagtgga attagagtaa aggaagattc attatgaaaa agatttttgg
      541 tgtttctgtt gggctactta tgatgttaac atttggaaat gcagtatatg ctgctgagaa
      601 agaagttatt tcagatccag agcagtacgc ctcacgatac tttgctgatt ttgaagaaga
      661 agataaagta cttgcattgc cagaaggtgg ttttttaaaa ggggaagcta aaattgtatc
      721 tatggataat ccagatataa ttcaaggttc atataattca gaaactgatc ctgcttcagt
      781 ttcagtgaca gaagcaaaaa aaattgttgc tgaaaaattc aaaaatgata ttgaaactac
      841 tccaattatg cctcgaggag catttccacc cgatgttggt actagcggac accttcttgt
      901 actagcagga ggaggaagct ataaatcaca gccatttagt ggtgcgggat ggcgttttgg
      961 aggtatgggt gtaaaaccag ctgatggtac aggcaacttt ttacgttgga aatcctacat
     1021 tgacgatgga agagtaggaa atgtaaatca agccaacgca actaaatctg gttctattca
     1081 aggaatggca ttgtatgctc gtgaaggatt caaatacttt gcaccaaacg ggcctggttg
     1141 gacaatgaat ataggtattt attacactta taatcctgtt gcaggtacgt attatgttgt
     1201 tcaaaatatt taataaaaca gcacaaagag atttctttgt gctgttttat tatttttagt
     1261 tgttgacaaa cactaaaata taaaatataa tcaacacata aacgaacgta tgttcggcaa
     1321 gaaagcaggg gatttttatg gatgagatgg ttttaagtac tcagaaatgg ctaaacaaga
     1381 aatacagtaa tgttacaggg tttgataagg ttccagaaaa tgggcgaaca gggtggccta
     1441 caatctatgg acttattgaa ggactacaag tagaacttgg tattactaat ctagtagcta
     1501 attttggacc taccactgaa aaaatgtacg ataatcaggt tactcctaaa tggggcaaaa
     1561 atctacctaa aaatattgta tttcttattc aaggtgcctt ttggtgtaag gggattaatc
     1621 caggtggctt cgatggggta tatactccat atttagatac tgctgtaaaa gagttgcaga
     1681 ctgatgcagg gtttaatgga agcgctgtaa ctggagtttt ggatgcgaaa tgggccaaag
     1741 cgttatttga tatgagtgct tttgttcttg ttcccggcgg agatagtaaa attagaaaaa
     1801 tgcagcaatg gttaaatgta aattatttag aatacacggg aataatgcct tgtgatggta
     1861 tttatcaaag aaattcaaat caagcattaa tttttgcatt acaagctgaa ctaggatatt
     1921 ctcccagtga agcaacaggg tcttatggta atgggacaac tagtaaaact tatcctgtgt
     1981 ctgaaggtaa ctcgggaaac tatgtaagaa taattcaata tggattatat gttaatggtt
     2041 attttgaaga cggtacattc gatggtattt tcactaaata tatgggttta gaagtactgg
     2101 cattccgaaa atttatggta ttgcctgaat atactgaaat agcagatgtt gttgtaataa
     2161 aaggactatt gtctagcgct ggagatatta gaagatctgc agatggcgca gatacttcta
     2221 cgcaattaac tagatctcaa atccaaacat tggttgataa tgatataaaa atagttggta
     2281 gatatcttac tggtactgtt ggaattggaa aagatgaacg aaataagtat ctaactacag
     2341 aggaattgaa taatattttt tctaaaaatt tatctgtgtt tcctatctat caagatggag
     2401 gtgcagcatt agcttatttt acttatgatc gtggcttatc agatggtaag aaggctatag
     2461 atgcagcaaa aaatctaaat ataccattaa caacagttat ttattttgct gttgatctag
     2521 acatgttagg ggaagaaatt cttgcatatg ctggagaata ttttaagggg gtatctgctg
     2581 taatgtcata tagcgggtat caaacgggtg tttacggaac aagaaatgtt tgttctcaaa
     2641 taatcaataa cgggtatgct tcgtttgcat ttgtttcaga tatgtcgact ggttatagtg
     2701 ggaatttagg ttttcctatg cctagacaat ggtcttttga tcaatttgtt gaatttacca
     2761 taggaagtgg caacggagct gttggtatcg atttaatcgc tacatcgggt agagatagcg
     2821 gatttaatga gttatcaaat gatactaata atgataatta cattgccaaa tacaatcaga
     2881 aggttataaa tcagatggta cgtgcgtatc aatatctatc acaagctggt cttgataatc
     2941 cttggaaccc tcatttgaca ttttatagat atgtaaatta ttctggtttg tcatgggaca
     3001 tcatttcttc tcctgtaaca gagcatgata gaaaaattta tgatgaatat aggaataaat
     3061 taactaatag cgagggcctg tataattatt ttatagatcc taatactggt tcaataatag
     3121 gtttgcctca cttaattgtg acgttacaat cacagatgtt tctagccgac acaatcaatg
     3181 atagtgtttc tgactttgca ggttggttag gagatttaat gacttgctgg ggtgaagtta
     3241 agaaattagg aatacaaatg gagcaaggtg tatttgcatt agtaggtacg gctgcaggtg
     3301 gaacatttag tctagaagat ttataccaag atgttgacgc ggtaaatgtt tataccttag
     3361 caaaaagaaa ttctgattca acagctttat cggctttaaa aacgtactat tgtgataagg
     3421 gtgctattga tagatttaat caatttgtta agaacagatt tggttcttca gataaaatcg
     3481 cttcagtaac aaatagttta ttagaaaatg acgaaacagt tgatatctta ggtgtaggga
     3541 taatttcatt tttcattgat aaaatagtta ataattcact tgggacagat tttacttatc
     3601 ttgattttat tggagatgag gggaaagttg caaatggatt ttctgaaaaa attattcaat
     3661 ttcaagaaaa tagaagtaaa cttaattaag aatcgtttac tatttaaaca g
//
LOCUS       DAFKHN010000151         3685 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFKHN010000151 DAFKHN010000000
VERSION     DAFKHN010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.155"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            163..1878
                     /locus_tag="LY912_002842"
     CDS             163..1878
                     /locus_tag="LY912_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6956449.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            1881..3644
                     /locus_tag="LY912_002843"
     CDS             1881..3644
                     /locus_tag="LY912_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6956450.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
BASE COUNT         1099 a          723 c          733 g         1130 t
ORIGIN      
        1 ttttttttaa aaaaaatagt ctattcaatt tctaaagctt cttcataata aaactttcat
       61 ttatgaaaag gcttgttctc ttttcattct aaatttccta agctacaatg tggtagtact
      121 tgttttttca attgtggaca aataaataat aggaggaatc atatgattca gttattacgt
      181 tatgcaaaag actatcgtaa gcaaatcatt ttgggcccgt tcttcaaatt tcttgaagct
      241 gtcttcgaac ttgtcctgcc tttaatgatg gcttccttga tcgataatgg actaaaaatg
      301 aatgaccgag gaaaaatcat tgaaatgggc ttatggatgg tcgctatgtc tgtgattggt
      361 ctgatttgtg ctatcatttg ccaatactat gcttcagtag cttcacaagg atttggtaca
      421 gagttacgta atcagctaat caaaaaaatc aatactttct ctcacaacga gttgaatcat
      481 tttggaacag ataccttgat cacccgaatg acaaacgaca tcaatcagct tcagctagct
      541 ttagcaatgg tcattcgttt attgatcaga gcaccgtttt taagtatcgg gtcagtggtc
      601 atggcttttg tgatcgactg ggaagtaggt ctgtttttct tagcattatt gcctattttc
      661 tcaatcattt tattttttat catcaaaaaa accgttcctc tctaccaaaa agtgcaagaa
      721 aaactagatc agctcaatga acacgttagt cagaatctta gcggtgttcg tgtcatccgc
      781 gcatttgcgc agacaaaaaa agaaacagag aagttcgata aaagcacaaa tgatctagcg
      841 aacaattatt tacgtgtttc caatatctct gccctattat cacctgctac aaccttgatc
      901 atgaatgtcg ggatcatctg tttgctgaca gttggcggga tcaaagtaaa tattggtagc
      961 ttgcaacaag gacaagttct tgctttgatc aattatatga atcaaatgct tttggcactg
     1021 atcgttgttt caaacctcgt cgtgatcttc acacgtgccg aagcttcagg aaatcgggtg
     1081 aaagaggtgc tagacacaga aaattcgatt cttgaagctg aggtcagtac tactcccgat
     1141 ttttcttctg aagcaattat cgcttttgac catgttgact tccgttatac tcctgattct
     1201 ggtctttctc tccaaaatat tacatttcag ctgaagcgaa atacagtcct tggaatcatt
     1261 ggtccaaccg gaagcgggaa aacgactttg acacaattga ttccgcgttt ctatgatgtc
     1321 agttccggta cagttataat ggacggaatg gatgttcgtt cttggcagct ggatcatctc
     1381 cgtcagcaaa ttgctcttgt tccccaaact tctgtactat ttaccgggac tattcgtgaa
     1441 aaccttcaat ggggtaagaa agacgccaca gaaaaagaat gttgggaagc tctgaaaatc
     1501 gctcaggcag aagaatttgt ccgtcagctt ccaaatggtt tagatacaaa agtcatggaa
     1561 aatgggaaaa atttctctgg cggacaaaaa cagcgactga cgattgcaag agctttgatt
     1621 gccaagccag cattactgat tttagatgac tctttaagtg cgttggatta tcaaacagac
     1681 ttggatttgc gtaaggcgct acagacttat cttggcagta cagtgattat tatctcccaa
     1741 cgtgtccgct ctattcaaga agcacatcat atcttagtga tggatcaagg taagattgct
     1801 gctcagggta cccatgaaga attacttgct caatcagcag aatatcagga aatcgtcgca
     1861 tcacaggagg aagaatagtt atgaaagtaa aaaaattatc cttgcagacg ctccgccgat
     1921 tcattcctta ccttactgcc tatgcaaaag acatttggct agctgtgata ctaggaatca
     1981 tcaatgggat tgcaacagtt gtgatgacgt tacaaattgg tcaaagtatc gatcaaatga
     2041 ttggagaagg acaggtccgc ttcaatcgac tgttccattt acttattcta ttcggtggta
     2101 tcgttttaat caacgtagtc agtcaatggc tcatccaagt gttaagcaat cggttagctt
     2161 acttatccgt tgcaaaatta agaaaagatg catttgctca tctgaatcga ttgccacttc
     2221 gttattatga tcaaaactcc cacggaaata tcgtcagtcg atttacaaat gatatggaca
     2281 atatttccat tgcaatttct gcggccttca atcaattatt ttctggagtg gcaatcatca
     2341 ttctttcgtt tatttttatg atgcgtctaa gtccacttct gacattggtc gttctttgtt
     2401 ctacaccaat tattttcctt gtgagttgga tcgttgctcg tgcttcacaa acaaatttcg
     2461 atagacagca aaggattatt ggggatatct cgggctttgt gaccgaacga atcggtaacc
     2521 agaaaatcgt gaaagctttt cagcaagaag aagctagtca acagcaattt gaactgctaa
     2581 atgctgatct atatgaaaaa ggacaacggg cacaattttc ttcttccttg acaaacccgt
     2641 cttctcgttt tgtagatcac cttgcttatt tatcgattgg tttagttggc ggcctattgg
     2701 cattgaagag tggttcgtca atcactgttg gtgtgatttc cagctttacg atctactcaa
     2761 gtcagttttc taaaccattt atcgaacttt ctggaatcac gacacaactg caaaccgctt
     2821 tttctggtct agaacgagca tttgatttga tcgatcagcc agaagaaaag cctgatttgc
     2881 cagatgccta tgccttggaa cccaaaaata tcaaaggaaa agtctctttt gatcatgttt
     2941 ctttttctta tgaccccaag cagcgtttga tcgaagattt caattttact gcttatccag
     3001 gtcaaaccat tgctatagta ggaaaaacag gggccggaaa atccacactt gttaatttgc
     3061 tgatgcgttt ttatgacaca acaaaaggaa caattacagt cgatgaccat gacatccgct
     3121 ctatccaacg tgatacatta cgtaaaagtt ttggaatggt gttacaagat acttggctat
     3181 ttgacagtac attgcgagaa aatcttcgtt ttgggaatcc ggaagcaagt gacgcagaaa
     3241 tcaatgatgc cctaaaagcc tcttatatgt atgaatttgt agaacgtttg ccggaaaaat
     3301 tagatactaa gattggcggt caagggttaa agatatcaga tggacaacgc caactgttga
     3361 cgattgctcg aacgatgatc agtaatcccc ctatgttgat cttagatgaa gctaccagct
     3421 cagtcgatac attgacagag aaaaaaatcc aacaagcctt cttagcaatg atggaaggaa
     3481 aaaccagttt tgtgattgcc catcgcctgt ccacaatcaa aaatgcggac cagatattag
     3541 tgatggatca gggagctatt gtcgaaatgg gcacccatga tgagctgctt caaaaagatg
     3601 gttattaccg acggctctat caagcacaat tcacagcaca ataaaaacaa gcagtcttct
     3661 gggatgggaa gactgcttgt ttttt
//
LOCUS       DAFKHN010000152         3633 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFKHN010000152 DAFKHN010000000
VERSION     DAFKHN010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.156"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(132..716)
                     /locus_tag="LY912_002844"
     CDS             complement(132..716)
                     /locus_tag="LY912_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956451.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(927..1130)
                     /locus_tag="LY912_002845"
     CDS             complement(927..1130)
                     /locus_tag="LY912_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956452.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(1140..1562)
                     /locus_tag="LY912_002846"
     CDS             complement(1140..1562)
                     /locus_tag="LY912_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956453.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1800..2414
                     /locus_tag="LY912_002847"
     CDS             1800..2414
                     /locus_tag="LY912_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956454.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2579..3403)
                     /locus_tag="LY912_002848"
     CDS             complement(2579..3403)
                     /locus_tag="LY912_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956455.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(3427..3582)
                     /locus_tag="LY912_002849"
     CDS             complement(3427..3582)
                     /locus_tag="LY912_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956456.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
BASE COUNT         1203 a          635 c          517 g         1278 t
ORIGIN      
        1 aatattaaca aatgaataaa atccttacaa catttgagaa taagttatca gtagacactt
       61 acaaaaaatt ctcatactat tgtcactttt ctagataaat ggcaaaaatt ttcagcatta
      121 aatgacaaaa actaatgaga atttgtcttt ccatttttct cctccatttt tgccaaataa
      181 cgataaatgg tggttcttga gacgttccac cgttccgcaa tagtcttaat aggtgtaccg
      241 ctatccacta aagtcttcag taattccaaa tcttgttcag acaatttttc aggacgacca
      301 ccaaaccgtc ctcttgcacg agcagctgct cgtcctgctg cggatcgttc caggatcaaa
      361 ttacgctcaa attctgcaaa tgccgcaaac aaatgaaaca tgagctgtcc tgtagaactt
      421 gatttgtcca tcgtaatatt ttcttgaata ctatgaaaac tcacaccacg ctcattcagt
      481 cgattgacga ttgaaatcaa atcttccata tttctaccta aacgatctaa gcgccaaacg
      541 acaagtgtat cgccagagcg aacaaaatca atggccattt ctaatcctgg tcgattactt
      601 tttgccccac tcatatgatc agtaaaaatt ttttcacaac caaatttatt taggctgtct
      661 tcttgtaaat ccaaattttg taaaccagta gatacccggg cgtatcctat tttcaaaaaa
      721 atcactcctt cattaatttt attgtaacat aactttatcc atatagttta actgaacata
      781 gatattgtta tgggtttatg aacatgaaat gaattgtttt tttgaaaaat aaagcaaaaa
      841 aagaaagtgt ccagaaatgg gtgattttat gaacactttc aattagaaaa aaagaatgtc
      901 gactagacac tcttttttta aaatcattat ttttcttttt gatatgtttt ttggtctctt
      961 ttttttcttt tttcttcaga atcttctaga ttagaaattg atttttgaat tttttgtgtc
     1021 tcctgtaaag ttcgctgaac ttgtaaagct gattcttctt tcggtaaatt aattttactt
     1081 agaatatcgc tatcttgata aaaatttggt gtgttcacaa attctggcat aaaaaatccc
     1141 tactttctag ttaaggttcc tgaataagtc gcaatccaat tgtttccagc tgatttataa
     1201 ctttgtaaat acaattttcc atagtaccaa taaccatttc ttttttcttt ccaattccgt
     1261 gattgaggag gtctagaagg ccaaccaact ttatcaaaaa tcatcgttcc tgtcactcgt
     1321 atcgttttag aagctgctag agcaagtaat ggagaaacta ttaaataatt ttcagtaaca
     1381 gttaagtcgt tagttgggtt accaatggct attccgtccc tatctaaagg agttaattct
     1441 tggttattat ctactacagt agttggttca tttgtactat cagcaaatgt aggaattgta
     1501 gttccagtta cactaattcc aatagttaaa atacctaaag ataaaataaa cttatttttc
     1561 attgtctatc acctcgaaat caaaactaag aaaacgtttt cttaataaat cttaacagat
     1621 aaatcaagtt atatactaga aaattcataa aatatatttt taatgtcata atcgtttaaa
     1681 ttttcttgat tgacatttat ttacaaaaaa tattgccatt taaaaagaaa agtgacatat
     1741 ggcttcctcg tgtatgatta gggtgtattt taaatagttg cagaaagtag gtaaaagttt
     1801 tgagagttgc atacatacgt gtctcatcga tcgatcaaaa tgaacaacgc cagattgaag
     1861 aaatgaaaaa attcggtgca gagagaattt tcatcgagaa acaatctggc gcaacgatta
     1921 ctcatcgacc tgttttccaa gaagcattag attacgtccg agatcaagat atttttattg
     1981 tggaagctat tgatcgactt ggaagaaatt atgacgagat catcgcttca gtcaattact
     2041 tgaagaagaa aaatgtgaag ctgatcatta ctagtttacc gatcatggct gaagcaattg
     2101 gcaatcctct cctggataaa ttcattaagg atctgatcat ccaaattttg gccatgatcg
     2161 ctgaacaaga acggactgaa tcgaaacgtc gccaggcaca aggaattaag atcgcaaaag
     2221 caaacggcgt ctacaaaggg cggcccaaat tatacagtgc agacgcaaaa gatccccaac
     2281 gtcgccttgt ttacaaaagc atcgttgaag atcttaaaaa tggtgttgcg attgctaaga
     2341 ttgctaaaga ctacaatgtt acgagacaaa ccgtgtatag aataaaaaaa gacagcatgg
     2401 tcaatgacaa atagttgatc atgctgcttt tattatcttc tcatctttaa tttcctacat
     2461 ataattacta tctataaaat taagtcttac tcagaacaga taaagcataa aattccaaca
     2521 aaccattttt tacttaacta aataaagagt ctgttaatat aatcttcact tatttacgtt
     2581 aatcccctac tgtatttgtt ggttccttat ctatattttc tacaaaatcc ttattatctt
     2641 gtgatttagc ttcgtataat tctttgtatg tcgacacatt ggttatacta attcctatag
     2701 ctagttcttg agactctact tttctctcta gctcctttga caaagtgatt tgagatttat
     2761 ttggttccgt tggagtcaat tctatagatt cttcataaaa atctctatac ataaagctat
     2821 cattaatttt ataaaaaaaa ttaaatgttt ttagcactgc catataacat tcaaaacatt
     2881 cttctatagt tggtttactt ccttgaggag aatgaaccaa tttattacgt ttttctatga
     2941 aatttttaat ttcctttctt atttctttcg gaaactcaat attaaagtac cctttaaaca
     3001 tgctccctaa taatttgtct acagggggag attgtaaatt ctcaaatatt agagttaaat
     3061 caggtttctc ttgttgataa aattccttta cccctatttc acaggctgta attatcgaaa
     3121 taaacctatc tctagtattt gatatatttt tacttctttt aaggagtata agagaaaagg
     3181 ggatactttc gtgtccatgc atgtaattaa ctaattgttg agcttcagaa gttatatctc
     3241 taattatata gttaacggaa ttaggaagtg tctttaactc taatgaaatt tctatccaat
     3301 tactatcttc taatctgtat atgctcgaag tataatttga ttcgtcagca agcatcgcta
     3361 catcccaaac actgatcata aaatctttta aacgttcaat catttcagca atattgctaa
     3421 aatcagctaa tttttcttta gaataaaaaa aacatttata tcagaatcaa taaattctat
     3481 tttttttatt actatatcgt catcattatc ttgaccattt atgtttattg ttccctgagt
     3541 ggggagtact tctttcaaat tcaagttaaa tttatattcc attacttctc ctccaatata
     3601 taaaaattac ttaactgtat ccaaatttaa tat
//
LOCUS       DAFKHN010000153         3607 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFKHN010000153 DAFKHN010000000
VERSION     DAFKHN010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.157"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(228..905)
                     /gene="nth"
                     /locus_tag="LY912_002850"
     CDS             complement(228..905)
                     /gene="nth"
                     /locus_tag="LY912_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBM6956457.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(912..1610)
                     /locus_tag="LY912_002851"
     CDS             complement(912..1610)
                     /locus_tag="LY912_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBM6956458.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            1878..3062
                     /locus_tag="LY912_002852"
     CDS             1878..3062
                     /locus_tag="LY912_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBM6956459.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3068..3511)
                     /locus_tag="LY912_002853"
     CDS             complement(3068..3511)
                     /locus_tag="LY912_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBM6956460.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
BASE COUNT          929 a          722 c          606 g         1350 t
ORIGIN      
        1 tactggactt attttatagg tatattggaa ggcattattt tctacatcgg gtattttccc
       61 aataaaaata acaactttta tttttatcgc aataaattgt aataagttac catcctagct
      121 actgagtatg tacatttact ttttcatgca aaaaagataa acgaaacagc ttttctccat
      181 aataacaaga taattcatac atttatttgc aattaaagaa accacgtcta caggcgtggt
      241 ttctttttta gcgccttttc ttttagacgc atccgatttt tcccatcttg acatattgat
      301 agcaaaggac atacctcgca cttgggattt cttgccgtgc aatgatatct accaaaaaaa
      361 atcagtgtat gatgtgtctt tacccataat tcttgtggta ctttccgcat cagtgtttct
      421 tctacttcca tgaccgtagc atctagtttg cagatcctca ggcgttttga gacacgttcc
      481 acgtgggtat ctactgcgat tgctggtatc ccgaatgcat cccccaatac gacatttgct
      541 gtctttctgc ctacaccagg aagagacatc aattcttctc ttgacgttgg cacttgccca
      601 tcgaaacgtt caatcagctg ctgtgcacac gctttgatgt tttttgcttt atttcgatac
      661 aaaccaatcg tttttatttt aagaatgatt tcatcgattg aagcttctgc taacgcatcg
      721 ggtgtcggaa aagaggcaaa caaatctggc gttgctttat tcactgatac atctgtcgcc
      781 tgggcactta agatcactgc aatcaataac tcaaatggat tattgtgctt gagttctcca
      841 tgtgcttcgg gaaacattcc atacatcgtt tctagagctt ccattgtttt ttgtttgctt
      901 aacatattcc gctactcctc caaccaattt ttcagtgaga ctttcggcaa ttcttcttgt
      961 tgagctgact gttctacttc tctttgaaga agctgctgtt ttcttcgttt ttggtcttct
     1021 tccacttgtt gttttgtacg tagatttttt ctttcccacg atagcaaaat gcggtcaacg
     1081 taattaaaac tataagcctg atttaatacg gcttcccgca gtgctagctt caaaatttcc
     1141 ggctgataat ggtcttcttc tagccattgt ccgatccgct ggaactcgat cgaagaaagc
     1201 gggcgtccaa attcttgttc aaataattga tacactgact ggatttcttt ttcttgtgtt
     1261 ttttcttcgt attttttttc ttgtgttttt aaatactcac ctaatagatc atagatgggg
     1321 taaagattat atcgatctgc ttttttaccg ttgacaatcg tcgtttctat cttgataaat
     1381 ccatttgtta cgagacgatc cagtatttga aaaatctgat cttgtttgat tcccatatcc
     1441 atagcaatca tctgcaaatc agggaaagta tctccttcaa gctgtgccat atgcaactgt
     1501 agaacaaata aaaattcttc agattgtaga ccgatcctat gataattttt aagtaaaaga
     1561 ttagatatga ctgtttgtcc agcgcttaag taattttcta aattcaacat gatttctcct
     1621 ccgctcaatc acagtatacg taaaaaaaac atgggaagca agaacaggtt tcttttctat
     1681 ttacttcact gatcggtcag atttacaatg tcgtctactt gatttttgtt tgttcatgtt
     1741 tttgatgcgt atcttcactt ttcggaataa ataaattaag tagatttcgc tgttccttag
     1801 aatgttgaca aggaaacaaa attactatac actatttttg tttccaagtt aacattattg
     1861 cataaaggag tttttacatg tacagtttca caaataaaca ttctaaagtt tttggatacg
     1921 tctctgtctt attcactgga ttaggattta ctatcgtcag tcctgtactt ccgtttttaa
     1981 cgctgcctta ttctcactcc atacatcagc aagctttcta tatcactttg ctcatgtctg
     2041 tttatgctct agctgccttc ttatctgccc ccattctcgg tagcttaagt gatcattttg
     2101 ggcgtcatcc gatccttatt atcagtttat taggatcaag tatcggatat ttgctttttg
     2161 gtttaggaaa ttcgatatgg atgttgttcc ttggtcgtat cattgaagga ttgacggcag
     2221 gagaaatctc caccttatat gcttactttg ccgacatcac ggaacctaat gaaagaacca
     2281 aagtttttgg atggatgggt gctttagtcg gtataggaac aacgctgggt cctattatag
     2341 ggggtctatt agctgagttg gggaattctg ttcctatatt tattggagca ctctttactt
     2401 tcttaaatgc cgtttatggc tacacattta tgctagaaag ccttccaata aaaaaacgtt
     2461 cagtagattt aagtttctcc catgtaagac cttttcacca attacaacaa ttattcaaga
     2521 tttcatccgt tattccttta ttgacagcag gttttgctgt ttggttggca gctggctctc
     2581 ttcaatctat cttttctcaa ttttcgattg acgcctttca gtggaaggct gggttggttg
     2641 gtttaagctt ctctttgatt ggaatcttgg atactgtctc gcaattgttc attatgcctc
     2701 gattgctcaa aaaattttca gaacagcaga tcacaagaat agggatgttc agtgaaatcc
     2761 tcgcctatct attcatcaca ttatctggaa ttcttctact gccgattttg tttttatttg
     2821 ggattatctg ttatggtttc ggtgattcta tttttactcc tgtattcaat ggccaactat
     2881 ccaattctgt ctcagataac cagcaaggtc ttgtaatggg cggtacccaa agtatacaat
     2941 ctctatcgcg cgtcatcggc ccgctaatcg caggacagct ttatgctgca gcaccatttc
     3001 ttccgacggt attcggattt ttgcttatga tttttgccta ttatcactac aataaaaaat
     3061 agtagcttca tttgctactt cgtataaatt ctctgtatcg accgataaaa cgaaatactg
     3121 tgtcaaattc ttcttttgac atattttcaa atacagtagc atctcgctgt acccattttt
     3181 gatggagttg ctcgtgtcta ttccttattt tttgtccgat tggcgtcaat tgaaaataga
     3241 tttctttttt attctcttcg ctttgataag tgtttatgat ccctctagct atcagttttt
     3301 ttgttagctt actgatggct cctctagtca tgtaactagc attcgctaat tttgtcacgt
     3361 taggatcagg gattttcccg atatgttcaa tcacttctag ttcatttaga gtaaatcctg
     3421 caaattcttt ttccatttct ggtttattac gatgaataat ctcattagct aaatccagat
     3481 attcttctat tagcagttgt cttttatcca tttctacacc ttctttttct ttcattatat
     3541 tgtttttttg tttcctattc aacaaagata aaaatatttt gtaggaaaac ccaatctgaa
     3601 accaaga
//
LOCUS       DAFKHN010000154         3545 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFKHN010000154 DAFKHN010000000
VERSION     DAFKHN010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.158"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            191..1129
                     /locus_tag="LY912_002854"
     CDS             191..1129
                     /locus_tag="LY912_002854"
                     /inference="COORDINATES: protein motif:HMM:NF016640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF616 domain-containing protein"
                     /protein_id="HBM6956461.1"
                     /translation="MGRQELYSLAINELEKRNLEIHELNQKNNSILGMKIRNKINQLN
                     QMKKRDNLLPAKYTLKSMTGKGPIKDYSNRENRSDELRKKELTNQGTPKRIAVYSCIT
                     GNYDSIKEPDFSHPLVDYYLYTDNVITSEHWNIREIPKYISELKNNILINRYIKFHPN
                     ELFTDYDFTLYVDGNVTITSDITGLLNSSSKLGLSMHKHSERKSLYSEADALIAVGKG
                     NKESIIEQISKYREEGFPDNFGLAEATVILVDLNNSIAENLLDLWWREYLNSESGRDQ
                     LAFPYVLWKSGHAMKEVTTLGNNVYKSAKLRIISHY"
     gene            1375..2391
                     /locus_tag="LY912_002855"
     CDS             1375..2391
                     /locus_tag="LY912_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase"
                     /protein_id="HBM6956462.1"
                     /translation="MKMKILITGGAGFIGFHLSRKLLKETENQIVAIDNLNDYYDVQL
                     KEDRLTILYDYNNFKFIRMDLLEKEKLDSLFESEGFDIVIHLAAQAGVRYSIENPYAY
                     IDSNIIGFLNILEACRNFPVKHLLYASSSSVYGGNTKVPFSTEDSVDHPVSLYAATKK
                     SNELMAHTYSHLYKIPTTGLRFFTVYGPFGRPDMAYFSFTKNILSGKEIKIFNHGKME
                     RDFTYIDDIVEGITRLINKVPEPNSDWTDIDDLSSESWAPYKIYNIGNNKPVALLEFV
                     ETIEKYLGVKANKIFLDMQPGDVVRTYADIEDLEEKINFKPNITLDEGIKKFVEWYTV
                     YYLS"
     gene            2759..>3545
                     /locus_tag="LY912_002856"
     CDS             2759..>3545
                     /locus_tag="LY912_002856"
                     /inference="COORDINATES: protein motif:HMM:NF014051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBM6956463.1"
                     /translation="MDSSSNKSHSIAKKAFIYAIGTLSSKMISVIIIPIYAVYISVAD
                     LGSFDYQNTIAQFLSPVIFGAIWEAILRMGLGKEKNIQKKVVTNSICFVIANTVILAI
                     FLPIIYRMIFPNLEYYQLFVFQLIFTPILSVFQYIVRALGESKIFVMSGIIAAGINLL
                     LLTIFVVTMGMGILGLLLSIIISNVINLIFLIFRGQIFQYFATSSFDFLFLKSMLKYS
                     IPLTLNLTFGWLIVGFSRFYIGTYIGVTENGIFSFAMKFSSIIL"
BASE COUNT         1238 a          460 c          635 g         1212 t
ORIGIN      
        1 agtaaagaat tatatctact tgcttgcgta tttctttttt atcattgtgt gtttgatatt
       61 catcaatata agaggaactg cttttgtaaa tggaatccta ccattattta gagaaaatat
      121 tatttttaag gctgtttact atttttttga gtaagaataa atagcactta aaaatagaga
      181 tgagggattt atgggaagac aagaattata tagtttagct atcaatgaat tggaaaaaag
      241 aaatcttgaa atacatgaat taaatcaaaa aaataattct attttaggca tgaaaatacg
      301 aaataaaatt aatcaactta accaaatgaa aaaacgagat aatctgttgc cagcaaaata
      361 tacccttaaa tcgatgaccg gtaaggggcc tattaaagac tattcaaaca gagagaatcg
      421 cagtgatgaa ctaagaaaaa aagagttaac taatcaagga acacctaaaa ggattgctgt
      481 gtatagttgt atcactggta attatgattc tattaaagaa ccggattttt ctcatccatt
      541 ggtagattac tatttgtata cagataatgt gattacaagt gagcattgga atattagaga
      601 gatacctaaa tatatatcgg aattaaaaaa taatattttg atcaatagat atattaaatt
      661 tcatcctaat gagctattta ctgactacga ttttactttg tatgttgatg gtaatgtaac
      721 aataacttct gatattaccg gattactgaa cagttcttcc aaacttgggt taagtatgca
      781 taaacatagt gaaagaaaat ctttatattc tgaggcagat gcattaattg cagttggcaa
      841 aggtaataag gaaagtatta tagagcaaat tagtaagtac agagaagaag gatttcctga
      901 taattttgga ttggctgaag ccacggttat tttagttgat ttaaataatt caatcgctga
      961 gaatcttcta gatttgtggt ggagagagta tttgaactca gaaagtgggc gagatcagct
     1021 cgcatttcct tacgtgttgt ggaagtccgg acatgcaatg aaggaagtga ctaccttagg
     1081 caataatgta tataaaagcg ctaaattaag aatcataagt cattattagc cctaaatgat
     1141 ttctaaacta ttctttcaaa tcctagtaaa tatttggaga tagaagattt cctttttaaa
     1201 gtcataaaaa attaagttat attttttgag tgaatggaga agacgcatag tatcataaac
     1261 ttcgttatat cttaaattat ggggtatgcc taaataataa atgtaatacg agtataaaga
     1321 agaaagcaat tttgggttta accctattgg ttcctttcag aaaaaggtgg atgaataaaa
     1381 atgaaaatat taataacagg tggagcagga tttattggtt ttcatttgtc tagaaaatta
     1441 ctcaaggaaa ctgaaaatca aattgtagcg attgataatc tcaatgatta ttatgatgtc
     1501 caattaaaag aagatcgatt aacgatactg tacgattata ataattttaa atttatcaga
     1561 atggatctat tagagaaaga aaaattagat tctctatttg aaagtgaagg ttttgacata
     1621 gtaattcatt tagctgctca agcaggtgtt agatattcta ttgaaaaccc ttatgcttat
     1681 attgattcta atattatcgg ttttcttaat attcttgaag cctgccgaaa cttccctgta
     1741 aagcatctat tatatgcatc atctagttca gtatatggtg ggaacacgaa agtaccgttt
     1801 tcaacagaag attcggtgga tcatccagtt agcctttatg cggctaccaa aaaatcgaat
     1861 gaattaatgg ctcatactta tagccacctt tataaaatac caacaactgg gctgagattt
     1921 ttcactgtct atggtccatt tgggcgacca gatatggcct atttctcttt taccaagaat
     1981 attttatctg gaaaagaaat taagattttt aaccatggaa agatggaaag agatttcact
     2041 tacatcgatg atatcgtaga gggaatcact agattaatca ataaagtacc tgaacccaac
     2101 tccgactgga cagacatcga tgatttgagt agtgaaagtt gggcaccata taagatatac
     2161 aatattggaa ataataagcc ggttgcattg ttggagtttg ttgaaacaat tgaaaagtat
     2221 ttaggtgtta aagcgaacaa gatttttttg gacatgcagc cgggtgatgt cgttagaact
     2281 tatgccgata ttgaagattt agaggaaaaa atcaacttta aaccgaatat aaccttggat
     2341 gagggcatta aaaaattcgt tgaatggtat acagtgtatt atttgagtta attttgaaag
     2401 gaatattgaa gatgggtaat tcatacgatt tttttagctt tgttaggtat tttaggaaat
     2461 tctactttca aacgtgacga actttctcgc cgaatagata ttttctataa ctaaaagaat
     2521 ttctataaaa caaaattgtg tatcaagatg tgtgaactgg attctgactg ccaatattga
     2581 ttgatgagat tgaagaaata tatagttgat catggatatc tttatttgaa aagatcttag
     2641 ctattcacat attcaaaaaa atttttacta cgaggactca cacgatacag aggaatttag
     2701 gtagttctaa ttaaaccaga aagtcatcta tagatgtgag ttgagggagg tcatacggtt
     2761 ggatagtagc agtaataaat cacattcaat agctaaaaaa gcttttattt acgcaatagg
     2821 aacattatca tcaaaaatga tatctgtcat tataatccct atctatgcag tatatatttc
     2881 tgttgccgat ttaggaagct ttgattatca aaatacaatt gctcaatttc tttctccagt
     2941 tatttttgga gcaatatggg aagcaatttt acgcatggga ttaggcaaag aaaaaaatat
     3001 tcagaaaaaa gtagtgacga acagtatttg ttttgttata gcaaatacag tgatattagc
     3061 cattttttta ccaataatat atagaatgat tttcccgaat ttagagtatt atcaattgtt
     3121 tgtttttcaa ttaattttca ctcctatcct aagtgttttt caatatattg taagagcact
     3181 aggtgaatca aagatttttg tgatgagtgg tataatcgct gcgggtatca acctgttact
     3241 ccttactatt tttgttgtta caatgggtat ggggatactt ggtctcttac tctctatcat
     3301 aatttctaat gttataaatt tgattttttt gattttcagg gggcagatct ttcaatattt
     3361 cgcaacgagt tcttttgatt ttttattttt aaagtccatg ctgaaatact ctatcccact
     3421 cactttgaat ctcacttttg gatggctaat agttggtttt tcaagatttt atattggaac
     3481 gtacatcgga gtaacagaaa atggtatttt ttcttttgcg atgaaatttt catctataat
     3541 tttaa
//
LOCUS       DAFKHN010000155         3482 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFKHN010000155 DAFKHN010000000
VERSION     DAFKHN010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.159"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            149..382
                     /locus_tag="LY912_002857"
     CDS             149..382
                     /locus_tag="LY912_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBM6956464.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            379..786
                     /locus_tag="LY912_002858"
     CDS             379..786
                     /locus_tag="LY912_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBM6956465.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(1923..2441)
                     /locus_tag="LY912_002859"
     CDS             complement(1923..2441)
                     /locus_tag="LY912_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBM6956466.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1181 a          590 c          527 g         1184 t
ORIGIN      
        1 gggagcaatc taaatttttt gaattttctt aattaattat atagaaagaa caatctttct
       61 atagagttag acatgagagg gactatgctt gatttaaaat caacaagcgt atatactgta
      121 tatacaaaga aaaaggaggg agaagactat ggcaattaaa gaaagaaaat ttagggaagt
      181 ggggaactca gtagtattaa ctatttcaaa ggagtttctt aaagaaaatg ggttaaatcc
      241 cggagatacg gtttttttag atgaagaaaa acttcgagcg gcaattacaa aaaaacaagc
      301 cttatctgat gaaattgatt tagcaatatc tcaagcatta actgaatatg atactacttt
      361 tagagagctt gtcgataaat gagtattcat tacctagaag ccaaagatat tataaaaatg
      421 aatgtaatcc aaataaaaaa atactctcct aatgaacccc ttggtgtaaa ggatgcgaat
      481 gctttagaaa tgtgtgtagg gcaacttcga gcctcagctt ttggtgaaga ggtttatcct
      541 tcgatttatg aaaaagcagc tatcctactt atacaattga taaagaaaca tccttttcac
      601 aatgcaaata aacgtactgc tttcttagct acttttgtct ttttgaaaat caatggacag
      661 cttttagcta ttgatcaaaa agatgctgta aatttagcgg tatatattgc tacgtatgat
      721 aaggatttcg atcaactaaa atatgaagtg atcaacacta taaagacaca tacgcagccc
      781 atttaaggag ttactgtatg tgtctttata gggttattag ctgctatagc gaaataattg
      841 aagtaaatta caaatagcta taattcaaat ccaactatat agaaaacgta aattttctat
      901 atagttggat taagataacg actatttatt ttatcatatt tttactatac cctatacttt
      961 tacttggtat atttatgaat aatcgcaaat ttacccctat actactagtt tgtaagttag
     1021 attaataaaa atactaaagt tatttgttct tttattaaat acacctacaa cttataaatt
     1081 gatggtattt agataacacg aaagaataaa aataacagct gatagtaaag tttgttgacg
     1141 attgctactc aatcgaaagt gagttagtgc gtatgaactt gcttctgaaa acttatgaaa
     1201 tgaaagacct tttacatctt gcagaaatcg gtactgggat taaactaagc aataaaaact
     1261 aatgttcccc tcattctttg aacttctact atttgattta tttattctga taaatgacga
     1321 tttcaccttc aggatcttca aatcccgtat agaatttatt taagatctct tcagtatcag
     1381 taataggata ggcgataggc cacataccct ttgatggtta gaataaactg ctcaaaatct
     1441 gtatcgtatg ttggctttag catattaaca aaggctatct ccaaattata aaccataagc
     1501 gttgaatcgt tcttaacaat ttcaattctt cctaacccaa agtcagaaga tataattacc
     1561 ggacttgcct tacccttcat gtgggttgtt gagattccat atttaaaggg aattgtcggt
     1621 actatcggcg gtctgaaaaa catcccaaaa ataaaaaaat ctttcccctg ctagtctcct
     1681 aagtcccttt gtagcggata tggcaccata atctcatttt atcgaagtga gtcatggttt
     1741 atctgttggc caaccaaaat tgatacaatc taacgatgca ccctctacgg cattctaggg
     1801 gagtgcactt gcattcaccc aataaaaacc ggcagttagc aaagaactta tgtagtcgta
     1861 tgttcttact gttaacatac aagaggtctc ctttccacaa ttgcttagca gtaaacggga
     1921 atttacaaag ctaatctctt ccattttctt atctttgttc taaaagtccc aaatggagca
     1981 actgtattta catgaataaa tttatatact tcccatacag ccgttttggt tgcctcgtct
     2041 gcccattttc ttttgtgtgc agtgaataga tcttcatcac tcattgaatc aatcatcatg
     2101 ttaatatcat caatattacg attgagaatt tcctctaatt ctttcaatgg tagatgtgca
     2161 taggtatttg taaaccactt atataactct cctaactgat tccatttaaa ttgatcagaa
     2221 ggcgttttaa cagataatcc atttctttca tcattttccc attttagaat taaattcgtc
     2281 caaccaactt gatatgctaa attttcagca ggtgttctat ccacttcctc aactctttta
     2341 tccttcaatt cttcaggaat agtttcaaat tctaaaatat atttagtata agtcctattt
     2401 atttcttttt ttaattcttc tttattttta tatgttctca ttatattacc tccataaatt
     2461 cctaattgtc tcctttaatt catctataat ttcatccacg atattttaat ccgttctaca
     2521 atgcatatct gatatgcatt gactgtctaa ctcatatgtg aatgatttat aaaatatccc
     2581 aacgtctcat ctaaagaaat gttgatcgtc agcaaggagc taaaaaatac gaatatattt
     2641 cttttgtagt aaaatcggac tggtttgcat atcattttct tcgtaaatat caaaatcatg
     2701 ttaactacta tcaattacta ataaaaacta ccactttaag cgttaagaac tgttaagttt
     2761 agttaagtga ggatagttca caaaatccat tgttaaactt cacgaaagtg gtaaaactca
     2821 aaatgcttta tataggatta cagcatcgct ctttcttcga ttgcgcgttg ggtaaaaaat
     2881 attatgaagt aaaaattgac gatgacacgt tccttacggc tcatcagatg aaacagctac
     2941 aaaaacgaaa tgatcaactc gaagaaaatt taattctaaa aaagcgattg ccatattcac
     3001 gcctcgctcg acgaactatt aaaggtcaag atttacctga agatcatcct ttttaggaaa
     3061 ttgaagcttt ttatgttgca caatgcattt ataatactac aatgatgttt tcaccagata
     3121 ttcttctagg gtgcggtgta atgaaacaga tacacttgca aaagaaaatt caccgcgaat
     3181 ttactaaaat tatgaataat tatgttaatc ttccgaaatt tttttccaaa attaagggat
     3241 caagctggtg ttatagattg tttaaggttg gcaaaaaaat aacttctttt taaacaatta
     3301 tagaaaaccg atactctgtt aagttggttg acacggtgtc gatttttatg actttcttat
     3361 tctgaaactt cactaacgga cagtacctaa aaagtctata gtatggacgt ttacgagtac
     3421 tattttatca aaaatgctgc tcatttcaac ttatatgttt tagtgaacta cccccactta
     3481 gc
//
LOCUS       DAFKHN010000156         3399 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFKHN010000156 DAFKHN010000000
VERSION     DAFKHN010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.160"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..277
                     /locus_tag="LY912_002860"
     CDS             <1..277
                     /locus_tag="LY912_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HBM6956467.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            420..641
                     /locus_tag="LY912_002861"
     CDS             420..641
                     /locus_tag="LY912_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956468.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            657..1499
                     /locus_tag="LY912_002862"
     CDS             657..1499
                     /locus_tag="LY912_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956469.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1562..3364
                     /locus_tag="LY912_002863"
     CDS             1562..3364
                     /locus_tag="LY912_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HBM6956470.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
BASE COUNT         1230 a          469 c          702 g          998 t
ORIGIN      
        1 agaactcatc aagctggcta ataagggtca agattatgaa catctagcag atgagattga
       61 tgagctgaga gacaagcgac agctcctttt agtagaagat gcctccctca gtggcgagaa
      121 cgagcgaatc aatgagctga ttgaatttat ccgcaagaac aaattccgta ccttagagta
      181 cgatgataag cttgtaagga agataatcca gagcgttaca gtctatgaag aacacttcgt
      241 catatccttc aaatctggca tcgaaatgga aatatgaaaa ccagaagtaa atagcccatg
      301 attctacagt agagtcgtgg gttttctttt gcttgctgat tataataata ttttaataac
      361 tattgttatt ataaaccaaa tgatttataa tattcttagc gtaaacttgg aggtgctgta
      421 tgactacggc agaaatgatt aaagaactgt gtgagcaaat gaatataagt gtttccgaac
      481 ttgctagacg tattggacag actccacaga atttcaataa gaaattacaa cgagaaacgg
      541 taaccttaga tgagttgaaa gcgattgctg atgtgctagg tgtcaagttt gtgcaggctt
      601 ttatattgcc tgatggcaat gaaataaaga taggtaatta ggaggtgtaa tttgtattga
      661 aaatcataac aataaatgat gttgagtatg ctgtatttgc tgctaatgaa ggtacttcca
      721 aaccacaacc tcatatcata gaaacgaaat ctggtactat tccagaagga aaacaactga
      781 gtttattaaa agaatatctt aagcagaatg atatttcccc aataaaagga gcaacaacat
      841 attggtgcat tgacaaggtt cttaagcttg attcaagtaa agaaaaaact ataagtgaaa
      901 caatccataa acaaaaatac ttatctttaa ctgaagaaaa tattgagaaa cagcataagt
      961 ttgtaggtgc aagctctaat tatgggaaag aaggtctaat aatacatgat gttttgaatg
     1021 catttcctct tcataatgat ttaaatacta ttgcgatgaa gattgcggta attgatgtaa
     1081 caaattcaac acatctttct caatataaga gcaggttgtc tctatatgat ttggctaaag
     1141 taattctgga gattccaaat tttgatgatc ggttggcaaa aggagatcct cagttgataa
     1201 atattatcgc aaggaacatt ggtgcagtta atatgttctc atttgcatcc aagtactgta
     1261 catatcataa tgtggaagtg tgtgggagag atgattactc catctttgat ggtatcgtta
     1321 aaaatactct tccacactat atccaaggac taactacgaa taagattgat acgtggcgaa
     1381 gaagttttga ttacgaggca tttaacgaat gtgttggaaa actacttgat gaaaataata
     1441 tacatattcc ttttagaaga agaaagttag atcacttctt gtggtatgcg aataggtaga
     1501 atataagaaa aaggcatcgt aaaagtgatt ctggataaaa ttaatggggg aggaaataat
     1561 agtgggatta tttgattttc taaagaaaaa acaaggaaag gttagtaaac acgttgatta
     1621 tcaactggct tctagtctat ttcgtactgg taaagttttt gctgaaaaat tggaagtgga
     1681 catatcaaat gtagatgagt ttcgtaaaac ttttatcgct tttgatgtgg aaacaactgg
     1741 cctaaattct tcttcagata gaattgtaga gattggtgcg gtgctattta aagaaggagt
     1801 tccaattcaa tcattcggaa ctcttgtcaa tccaaaagtt agaattgcag cctcagcttc
     1861 ggcaataaat aatataacta atgaaatgct aaactctgct ccaaatgagc aggaagttta
     1921 cccccagttg gtagaatttt taggagatgc actagatgga aaaatcacta tgtgtgcaca
     1981 caatgcaagt ttcgattttg gatttttaag taacacattt tctagacttg ggtatgatgc
     2041 taaaattaag tatgttgata ctctgagtct ctctagaaaa catataaaag gcattgtaaa
     2101 tcataagcaa gagactgtag cggaatattt cggattaata aatgacactg cccatagagc
     2161 ggaatcagat gcagatatat gcggaaagat tttttggggt gttttagata ttattgagga
     2221 gtcgttggaa gaacaaaaaa agcaaataga aaagatgact ccagacataa aagaacttga
     2281 agcttgtgct tttattcaag atattattga gaaaaaagga tgcgacacca gttggatcag
     2341 gtatcgaaaa aacagtaata attatgtcga tgtaacttgt ctatatacat tcttaaagtt
     2401 taagtttgct aagaagggaa attacatcat tattagaaaa gatgctacaa atggaattga
     2461 tttacctata gaaccttgta ctgtaagtga aggcggtaca acaaatgtgc gagtctattt
     2521 tcgtagcccc tttgacttaa cgcctctttc aaattatatt ttcagtgctt atagcgattg
     2581 ttataattct atgaatgaat atatgagtgt tagtaattac actaaaaaag aagcagagca
     2641 aagccttagt atgctgaaat ctatttcaaa atcagcgatg aaagagttat tattcgatgc
     2701 aaaaaatcgt ggatatgatg agactgaagt taacctaaat attgaaaaag tgatatctag
     2761 agaagatgta attattaacg ggttgcataa tcgagtttca ttaaacaaga tacgaaatat
     2821 agggaattgg gagaaaggat ttgatgcagg ttatccatat tgggaacgtg gagaaactgc
     2881 taggaaaaat ggcaaagtag atgaagctat tgcacttttt gataaagctc gatataacgg
     2941 ctatgatgct cctgcgctat atgattctta tgctaaagct tatcgaaaaa ttaaggatta
     3001 cgataatgaa attctcattc ttgatgaagg aattatgcgt aaaacacggc acgatgttgg
     3061 tactttagag gctcgtaggg ataaggcaat taagctatta tttgctaaac aagaggcaga
     3121 gcggatagct aaggaaaaat ctgattttct aaaagcgaac aaaaaagagg atgcgattag
     3181 tgagcctagc aagaagcgtg gaagacagat tattcaaatg actgatgatg gaacaataat
     3241 aaaagaattc gatactatag cttctgctgt aaaagaagtt ggcgttaact caaaaagtat
     3301 tagggatgct gcaaatggag ttcaaaaaca tgctggagga tactactgga aatacaaaga
     3361 ttagcagata atctaagata acctaggatc ttcttaata
//
LOCUS       DAFKHN010000157         3376 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFKHN010000157 DAFKHN010000000
VERSION     DAFKHN010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.161"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            247..432
                     /locus_tag="LY912_002864"
     CDS             247..432
                     /locus_tag="LY912_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956471.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALVGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            445..693
                     /locus_tag="LY912_002865"
     CDS             445..693
                     /locus_tag="LY912_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956472.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKITPKEFIEKHLVDL"
     gene            724..894
                     /locus_tag="LY912_002866"
     CDS             724..894
                     /locus_tag="LY912_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956473.1"
                     /translation="MGKFNRALVFSTPFIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            complement(992..1657)
                     /locus_tag="LY912_002867"
     CDS             complement(992..1657)
                     /locus_tag="LY912_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956474.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDHLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            1712..2410
                     /locus_tag="LY912_002868"
     CDS             1712..2410
                     /locus_tag="LY912_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBM6956475.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFSEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLKEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            2588..2929
                     /locus_tag="LY912_002869"
     CDS             2588..2929
                     /locus_tag="LY912_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956476.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            2922..>3376
                     /locus_tag="LY912_002870"
     CDS             2922..>3376
                     /locus_tag="LY912_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBM6956477.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDT"
BASE COUNT         1268 a          496 c          639 g          973 t
ORIGIN      
        1 attagttaaa ggtgttgaca actaataaaa ttgttagtat actgttttcg taagctaaaa
       61 tattagctaa aaagacttga taactaataa acacttcacg gtcggcaaac tctgaaatgt
      121 aaattactag gcatttctgt gtcttattta gctatatcta tatactaata aaaatattag
      181 ttattgtcaa cgaatattag ctaatttttt agcttacaga ctatttttta gaaaggagct
      241 atttttatgt ctgagaattt agacttaaaa attcgagcgg agatgagaaa aagaagaatg
      301 actttcaaag aactagctgc gcttgttggt atttcaggag cttatttatc agatattcta
      361 aacggcaatc gtgatggaaa gaaagcacaa cagcatatcg aaacagtgaa aaaaatattg
      421 gacatccgat agggggggta ggcgatgaca aaactaaaaa aacaagattt tgtaaaaaaa
      481 tacaattatt ctccatctac ttatcaacgt cgaatgtcgg aactaaaaaa tacagcaatt
      541 ttctcagcgg cgtatgaacg ggtcacagga caagaagttt ggatcaatac agaattatac
      601 gataaatttt tgtctttcaa atcctataac aggttacgca caagaaagat aacacctaaa
      661 gaatttatcg agaagcattt agttgattta taaaaaacag aacattttga gaggtgaagg
      721 ttaatgggca aattcaacag agcactagta ttcagcacac cattcatcat ctacgcttta
      781 ggcctctggg gaagcagaca agcgttgata ggaacgattg tttacatggt ttggattttt
      841 atggggctgg atgaagctga gtacaaaaca aaaaagccag tcgggaggga ctgactaatg
      901 aaaaaaagtt taatgactat aaacgaaaaa caattgaaag aaaattttaa tgatctcatc
      961 aaagaatttg taaaagaaac tggagaattt cctaatcaaa ttcatctagt tgcggagggg
     1021 catagccagt atcaagctgt gaaatttgag atgaagaaac aaatctattg aatttagcag
     1081 tacctctact tgtaagaaca tttattgtaa tgtttttttc gactaaagat tcatcgtatc
     1141 taaaaaccaa cgtagtaatt tttgactcat acggtggaat ggtaataggt aatgacaacg
     1201 gaggaaattt tgatagatca gcaccttttt ttaaagattt accagaatac gcacgtatac
     1261 catgtggaag ttcgtcatac attgatttta ccgttacaga ataattatca ccaatcattg
     1321 taaaagcatt taaatgatca ggaattccag aaatcgaaaa ctcaataatt gtaacaggta
     1381 aagaactgtt atttgttaac aatacagaat ctataatcct gaatttattt tgatggtaaa
     1441 catctggttt ggaatcactt tctctatcta tcaaccattc ttcgcattca gcgaagaaat
     1501 ccaattttaa attaaatttt ttgttttttc tatctgtata ggagatataa aaagcaaatg
     1561 ttgaaaatac tagagacgta ataggcaaaa taaaatcttt aatggtttta acaatgttat
     1621 tccagtcaaa ttgtttaata aagtcaataa gactcaattt ataccaccac cattttttat
     1681 ctacattata tcaaagagga gagaagaaat aatgcaagaa ttagtaattt tgaaaaataa
     1741 agaagctgtg actacgagtt tgcaagttgc agaaagtttt gagaaaaagc atcaacatgt
     1801 tttaagagat attgatgcac tgaaaaaaga tgtgtccaat tttggacaga tgttttctga
     1861 aggtaatgaa ccagattcat acggcagaaa tcgacgagtt ttcttcatta gtagagatgg
     1921 ttttttcttg ttggctatgg gttttacagg aaagaaagct atttacttca aacaaaaata
     1981 cattgaagca ttcaacgaaa tggaagatgt tattcgcaag aatactgttc ctcaaacaat
     2041 tgaagatatg atgatctacc aactaaaaga aatgaaagat gttaaaaaag atgtttccat
     2101 gcttaaagat actatgcgaa ttagtgggca acaagagttt gaaattaaac aaaaaggaaa
     2161 tataaaagtt atggaagttc tagggggtaa agaaagccga gcttatgaag aaatcagcaa
     2221 aaaagtattc tcaaaatttt ggtctgaatt taaacgtacc ttttcaatcc caagatatgg
     2281 cgagttacct cgtaagagat tcgatgatgc tgtttcattt attgaaatgt ggttaccaga
     2341 aactgcgatc cgcatggaaa tcgatcaact gaacagacaa caaagacttt tcggtgatga
     2401 aaatgaatag agctgaagcg ctaagaatcg ggacggtaat tgctaatcgc tggtggagac
     2461 acaataaacc aatcatccta agccaacaac atattgacaa gcaaaaagca tggcaacaaa
     2521 taaaaaagtg actccgccgg caagcaaaga gtcacaaaga aaacacatca taaggagatt
     2581 ttagcatatg gaaaaagaac tttccactct agatcaatat ttgactgatc ctagttgggg
     2641 caaatcgaat atcaaggaaa caaataatcg aaaaatcaga cgaaatcttt tgacggatga
     2701 agaactagca tgtgatcaag acgatttggg aaattttgtg agtatttggg atcatgtcta
     2761 tcttatccat ttatcgagga agtccaaaaa acctgaatat atctatgtca tcgaagatgg
     2821 cttgattgat gcgctagaag agtatgacag agataacttg attgatatct cttattacgg
     2881 atcaggtaag aaatacattg ctgaaatgga ggcagaattt gatgagtgaa aacaaaggga
     2941 caacgacttt tgaaaaactt tttagtcgca agttaaataa aatactcaag aaaaaaggaa
     3001 attttgatta tttatcttgg gctcacgcgt gggagattat gaaaaagaat gatccacagg
     3061 caacggtaac tattaatgag tataaacact acagggttgt ttctggaact catcaagact
     3121 ttcttgttga ggaatataaa ccttttctta tggatgaaac agggacttat gtatctgtct
     3181 cagtaacggt taaaggacac acggaaaccg agttatttcc tgttttagat tatcgaaacc
     3241 aaccagttgt taaaccaaat gcaatgcaaa tcaataactc attgaagcga tgctttgtga
     3301 aagcattggc tctacacgga ctgggattat atgtatttca aggggaagat attccaacac
     3361 cacctagaat cgatac
//
LOCUS       DAFKHN010000158         3282 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFKHN010000158 DAFKHN010000000
VERSION     DAFKHN010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.162"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            3..587
                     /locus_tag="LY912_002871"
     CDS             3..587
                     /locus_tag="LY912_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBM6956478.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(663..1856)
                     /locus_tag="LY912_002872"
     CDS             complement(663..1856)
                     /locus_tag="LY912_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBM6956479.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1920..2300
                     /locus_tag="LY912_002873"
     CDS             1920..2300
                     /locus_tag="LY912_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBM6956480.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2374..2736
                     /locus_tag="LY912_002874"
     CDS             2374..2736
                     /locus_tag="LY912_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956481.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1115 a          538 c          621 g         1008 t
ORIGIN      
        1 atatggcatt cccacaacta gatttaaaaa gtgaaaaagg accaaaagct gttatcaaaa
       61 caaaccgtgg tgacattact gttcaattat tccctgaact agcaccgaag acggttcaaa
      121 atttcattga actttccaaa aaaggttatt atgatggcgt gatttttcac cgcgttattc
      181 ctgatttcat gatccaaggc ggcgatccaa ctggaacagg aatgggtggc gaaagtattt
      241 atggcgaaag ttttgaagat gaattcagtc gtgaactgtt caaccttcgc ggagctttat
      301 ctatggcaaa ttcaggtcca aacacaaacg gaagccaatt ctttattgta aataacacaa
      361 atgtgccagc taatatgctt ggacaactag aaggtgctgg attcccatca gaaatcattg
      421 aagcgtataa aggtggcgga actccttggc tagatttccg acatacagtc tttggacatg
      481 tactagaagg gatggacaca gtagatgaaa tcgcaaatgt acaacgtggt ccacaagacc
      541 gacctgtaca tgatgtagtg attgaaacaa ttgaaatttc agaatagttt ggtatggtac
      601 ggagtaatta tgaaaaagga cgaaacctag taaggtctcg tccttttatt ttgaataaat
      661 atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag taaagtttct
      721 tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa cgtgatgcca
      781 ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg gtcgtctgaa
      841 atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat tattctcact
      901 ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc tagataagga
      961 atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc aatcagtcca
     1021 aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc agctttcatc
     1081 tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa agtcttggtt
     1141 gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag catggaagta
     1201 aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag aatcacttga
     1261 tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac acgccctcca
     1321 ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat ttttttctcc
     1381 atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct tcgaacgatg
     1441 tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc atgaatcaaa
     1501 atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt taacacacca
     1561 cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg ttcccaatga
     1621 atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc atgtttgatg
     1681 tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc tgctacccac
     1741 aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt tacactttct
     1801 gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc agtcattttc
     1861 gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga gggaagtaga
     1921 tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag ccttatggcg
     1981 cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa gtacaatccg
     2041 gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca gttcagatca
     2101 tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta gaaaaaacaa
     2161 atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt aagatcggat
     2221 ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct gaactagaac
     2281 ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga atttttatgt
     2341 aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt tgctggtaca
     2401 attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat tgatgacaag
     2461 ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa tatacttaat
     2521 ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga attgacaaat
     2581 acacatatta aagaggaaaa tgttccgttg tttgtctttg aaactgaaca aaagaatcaa
     2641 agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg ctctgttctt
     2701 ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc gaacaaagaa
     2761 gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac aatgaaatgt
     2821 tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa acggttgtat
     2881 aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa tttatagttg
     2941 accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga tgttatatca
     3001 catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg ataagataac
     3061 tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa cttcaaaaaa
     3121 gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag atttcgaaaa
     3181 acgaaatcga aaaaaacttt taaaaaagag ttgacaatcg cttgtctctc tgatatgata
     3241 taaaagttgc tacggcagcc aaaaacgaat cgggaaacac tc
//
LOCUS       DAFKHN010000159         3218 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFKHN010000159 DAFKHN010000000
VERSION     DAFKHN010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.163"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(435..1049)
                     /locus_tag="LY912_002875"
     CDS             complement(435..1049)
                     /locus_tag="LY912_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBM6956482.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1655..2032)
                     /locus_tag="LY912_002876"
     CDS             complement(1655..2032)
                     /locus_tag="LY912_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956483.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2332..3213)
                     /gene="galU"
                     /locus_tag="LY912_002877"
     CDS             complement(2332..3213)
                     /gene="galU"
                     /locus_tag="LY912_002877"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBM6956484.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          978 a          660 c          498 g         1082 t
ORIGIN      
        1 tgtattttat ttctattaga aaaaggtatc ctgttggaca attttgttat atcaggtaaa
       61 cttcattgca ataatgataa caaatgtact ataattactt tgtaaagagt tttggggaag
      121 actctttcat caacgtgtat taagagacaa gaaagaatcc atatggattc tttcttgtct
      181 ctttttccac tactttttat ttttctgaca ctacatattc ttataactca tttctcataa
      241 ctgtgaaaca acttataaaa ataacaaact ttaaacaaaa caagcttaaa atcaaagatg
      301 atccatctta aaataactaa aacaaaaaaa gtagtcgttg ttaatcctca ttaataatcg
      361 ttttcttttt ttcaaacgct ccatttttat gtggaacatt atttttttaa ggaactttgt
      421 caacatgtgg ataactattt tccacttgtg tcctggacta gctgttttgc tgtaaaatac
      481 aaaacttgct gcagcaaaaa gatcgttgca agagaggctg ttccgcagat cgctggatct
      541 agatttggca aagtcaagac tgcatcatgt aaattggcgt ggttgtccaa aaccaaatca
      601 gcaaattcaa ataatcgcaa accactgcta tgttgcgatt tgatacttcg tgacaaatca
      661 aatccagtaa caatgattaa tggatgacca ttttctttga tccactgagc tagttcgatg
      721 attgccgggt ttcttccttc attcgaaaga agaagaaaaa tgtcttctga tttgacagaa
      781 agctgatcaa taattgcctg tcctgcacct tctagcgttt catagacacc tccggctgga
      841 ttttcaatca atatacttgg tacaagatcc ggggtttgat cccaaaattc aaatgctaca
      901 ccacttagtg tgcggctagc atatatctgc aatctaccac cttgattaat ttgtttcgcg
      961 atccaagtgc cagcttgaag catcagcggc tcttctatcc ttaatttctc ttccaattgg
     1021 tgataatagt caaaataaca taaactcatt tatctctccc gcctagctat acttgacatg
     1081 aatagaaaca gctgcctaat ctaaggaagt acataaaaaa acagtagtta gacagtaaca
     1141 catgtggtct ttgctgtttc aaacacaaaa aaggcattga acgaatacgc ccaatacctt
     1201 gacatagcaa ataaaacaac gtgcagacca tggaaaatat ctacataggg gtagaatttt
     1261 caccctagat taggtacaat aaattaggtc gatgcactgc attgactatg gcaaaatgat
     1321 cggtcagggt gtatgtgtgt gactggtcat tccctgattc ttagcgccaa ctaagggtca
     1381 gggagccttt ttttattcag ctgtttctat ctgaatttat tgtaagtaat ctcttatcca
     1441 agtgcaagca agaaaataca aaaaaacatt ggtatgattt atatatatat aaataacata
     1501 aaaaaaggaa tggcttatcc cgatacaaca agcattcctt taaaaaagat tcttttatat
     1561 aagtgaaaaa agcttttttc caccaattaa ataaatctct catctcaata gtttatccat
     1621 tattttatct ttttttgcgt atacctacta aatattaccg tcttcttctc gttcttctac
     1681 tttgttcgag agaatctgta ctagaaaaag tagttgtatg tctacctttt ctgcctatcc
     1741 gagactttct tttcatatat gggatataaa tgattagata cagtacagca aaaaataaag
     1801 caaatacgca agcttcccaa ctacctaacg ccaattcaac catcaaggta gcaaccccaa
     1861 cggatgctgc ataccagata aaaatcagaa acgtttcttt ttttctgacc atgcgaaaca
     1921 tgataaatag actaataagc aatagtggca acacaaatat ccaattgctt ccttccatca
     1981 gccacttgag tatatcaagc agcgactgtg caacagcgac taattttccc atagtgaaca
     2041 cacacctttt tttataatta aaaaattcgc ctttttattc tactatgaat cttctggctt
     2101 ggctttcatt tctcttatgt aatcattttc ttttatacaa cttaaaaaaa aattaaacca
     2161 ttagcataat attttctgaa tctattcacg aaagtctttt tctatctttc gttttccacg
     2221 actcaactga tctagagtca aaaaactaaa acgacagttg cgcaaatgac gcacaagctg
     2281 ccgctttaat aacaaatagc ctttcattct cagcaggcca cttatttcca gttaactttc
     2341 tgttcttagc tttttactca actggataat atatgcactt aatgaagtcc caatttccga
     2401 atgttgaagt ccatattcaa tatttgtctt catatatcct aacttatcgc ctacgtcgta
     2461 tctttttcct ttaaactctc tcgcatagac cgcctctgtc tggttaagag tctgaagtgc
     2521 atccgttagc tgtatctcgt ttcctgctcc tggttcttga gtttctaata tctcaaatat
     2581 tttaggagtc agtagataac gtccgataat ggctaaatta cttggtgctt ttcccatttc
     2641 aggtttttct acaaaccctt ttactctgca acgacccttt tcgctatctg ttttaggatc
     2701 aataattccg tatttagatg tttcattttc tggtacacgc atgacggcaa cagcggaagc
     2761 ttgtgtttct tcataatcca tcatcaattg ttgagtcaat gggatatcat ctttcatcaa
     2821 atcatccccc agcatgacga caaacggttc atttcctata aatgcttttg cttgaagcac
     2881 ggcatccccc agtcctcttg gatgagattg acggatgaag tgaagattga cttgagtcgt
     2941 ttcttcaact aaagcgagta attctgtttt ttccttttcc cgcaaattgt tttccaattc
     3001 gatatttgca tcaaagtgat cttcaatggg tcttttttct tttcccgtta cgatcaagat
     3061 gtcttcgatt cccgaatcca atgcttcttc cacaataaac tggatcgttg gtttatccac
     3121 gattggaagc atttcttttg ccatggcttt tgttgccggc aaaaaacgtg ttcctagccc
     3181 agcggcagga atgactgctt ttttgacctt cacttgct
//
LOCUS       DAFKHN010000160         3150 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFKHN010000160 DAFKHN010000000
VERSION     DAFKHN010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.165"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..561)
                     /locus_tag="LY912_002878"
     CDS             complement(<1..561)
                     /locus_tag="LY912_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956485.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYS"
     gene            complement(548..2416)
                     /locus_tag="LY912_002879"
     CDS             complement(548..2416)
                     /locus_tag="LY912_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956486.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVL
                     YYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIK
                     FVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNN
                     DITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPIS
                     LLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAK
                     VIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKY
                     KAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENK
                     IEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            2382..>3150
                     /locus_tag="LY912_002880"
     CDS             2382..>3150
                     /locus_tag="LY912_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956487.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIFYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELS"
BASE COUNT         1058 a          511 c          458 g         1123 t
ORIGIN      
        1 gctgtacact agcaaactca tactcaatgc tagctttaca gacggatact tttcttcttt
       61 tccagagatg atttgataag cataaaataa tacagggata acaagtgtta ttgcgatagc
      121 ttcggcaatt gcggaacgat agtagatgtc tactgtccga taagcagaga aaatatagag
      181 acaactaaat aaaaatgccg cttttttttg ttttaaaaac cgctcgccat aatgataagc
      241 tacgagtgtt gtacacaagt tcaataacca aacgtaaata atatagctta caatcaaatt
      301 ttttgtcatc caatataaca ttacagctgg aaaaaaagtc agaaagggat aaaaataatt
      361 tacaccatat ccagtataat tgaatgtctc ataattaatc ggactggtaa aaatagtcga
      421 taaccccttg attcgagata agtgaaaaga aagatctcca gtggtataaa tactctgtgt
      481 atttttgaaa aagatgaaag aatatatact actaactata attaatccac tcaatattac
      541 tactttttta tttattttca ttcttcttgt ttatctcctt tttagtcaca tatcgagaat
      601 ctttcaactt attaggtgca aatcgtttaa aacttgaata caccactaaa caataagtca
      661 gaatactgat ccataaagcc atgagagcag ttggagtata ttttgttgta atttctatct
      721 tattttctcc agcatttaca tccacattca ctaagccatg ttttttataa gagtcattta
      781 cgactttacc gtttactttt acctgtgtac ctaaataagc atatactggt actgtcactt
      841 tttgcttttt gttgcttgcc actgtgtaag taatgttatt atctgcagct ttatacttcc
      901 ctttttccca cgattctcct acttttactt catgtttttc taagtgaggc ctttctttta
      961 tcgcttctgt tggggcgtaa tcgtataatc ctcccatatc tgatgttgta taacgtggga
     1021 gtgtttcttc attgataaca atatgaccgt gttttgattg gataactttt gcgtaatttt
     1081 cttttgctgc tatagacgtg acgagtagaa acaccacagt agcgccaatg attaaccatg
     1141 aatatttttt attcatagtc tttttcataa aaacaagcgt tatgatcatt gaagaaaaaa
     1201 agatttggat acctaagata cgccaaggaa actggagtaa gcttatcggt gttttttgaa
     1261 acaaaaacca tggaaataaa ttagttacgc atacccatgt agaaactacg ccaacataga
     1321 tgattttttc ttttttctcc atttctttca gtatgaataa aggaaaaatc aacgcaacca
     1381 atcctaataa ccccatagtg tatgttgtaa tatcgttatt taacgcttga atgatactat
     1441 ctgaaataga aagtgcttct agctgcaaat ctgttttgaa gggactgtgt atttcttgat
     1501 aattcatctg ctgcaacata ggataccaaa aatagctagt taatgcacaa gtcaaaaaaa
     1561 cagcctttac taaattcacg accacaaatt ttatatcgtt ttttatttgc ttgcttaaaa
     1621 acaaacgaac tataatcata caagcaatca atgcactaca caatagtgta gttaagacat
     1681 gagtatacac aagtagactt atactgacag ataaagcgat gacttttttt tctctattga
     1741 atatcaatcc ataagcataa tataaaacag ctgggataat cgtaagagcg attgcttctg
     1801 caattgcgga tcgataatag atatcaactg ttcgataagt tgcaaaagta tataaacaac
     1861 taaataaaaa agcagcatct atctttttaa aaaacttttc tccataataa aaactaatca
     1921 gaatcgtaca aatatttaat aaccaaatat atagaacata acttaatatt aagttatttg
     1981 aaattccata aaaaacgact gcaggaatta ttgtaagaaa aggataaaaa tagttcagtc
     2041 catctccata attgttaaat gttgtatagt tgattggccc ttcaaaaata gaagataacc
     2101 ctttgattcg tgaaagatga aaagataaat cacctgttgt ataaatttct tgagcatttc
     2161 tcataaaatt tactgaatat aaagtactaa gtaagataag aactactaaa agaaatgctt
     2221 ttttacttat tttcatagat ttgttgttct ccttttttaa ttctattttc agtatactag
     2281 aattgtcttt ttttaataag ttttgcgtta aatttttcat agcactagta tgatatacta
     2341 gaaaagaatc aatttttatt acttttaaat aggagaaaaa aatgaaaaaa aacaaaaacc
     2401 aaataataga tatcattttt atgttatttc taagttttgc ttacgtcatc cctctattca
     2461 tgtctaaggg aatctatcat agtgtcaatc aggatactta ctttcattta tctcgaatca
     2521 taggactaga taatgtatgg agttctccag taaacttcaa taacttcgat catcatggaa
     2581 caatgatgaa tattttttat ccatggctta ctctttatcc agctttttta ttttataaaa
     2641 tgatgggaaa tcttgtttta agttataata tcttctattt ttttatcact tttttaacaa
     2701 tggtcgtttc ttatttttct atgaaacaaa taaaaaacaa tcgttatatt tcgctgttat
     2761 tttcgattat ttatacattt tccgcctatc gtgccattga catattccat cgtgcttcat
     2821 tgggagaagc tgtcgcttta acatttttgc ctttgatact aatggggtgt tacgaaattt
     2881 atattagaga ttaccaaaaa tggtactggt tgtctattgg catgacgcta gtagtgtata
     2941 ctcatttact ttctgtcgct atggtttctg tatttattgg aggaacgttg tttctttctt
     3001 tttatttttg ggaccaaaaa atcgctagac tcttaagtct tttaaaagct accgtcctca
     3061 cctttttttt aagtgcggga ttcttaattc cttttattca acaatctaga gcacaagaat
     3121 tgaaagtccc actgggaaaa gaattaagtg
//
LOCUS       DAFKHN010000161         3075 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFKHN010000161 DAFKHN010000000
VERSION     DAFKHN010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.168"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            256..1224
                     /locus_tag="LY912_002881"
     CDS             256..1224
                     /locus_tag="LY912_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBM6956488.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1217..2248
                     /gene="vanA"
                     /locus_tag="LY912_002882"
     CDS             1217..2248
                     /gene="vanA"
                     /locus_tag="LY912_002882"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBM6956489.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2254..2862
                     /locus_tag="LY912_002883"
     CDS             2254..2862
                     /locus_tag="LY912_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBM6956490.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          906 a          588 c          754 g          827 t
ORIGIN      
        1 ttccagcgat gccagacttg gttgataaaa ggaggtccta agagatgtat ataatttttt
       61 aggaaaatct caaggttatc tttacttttt cttaggaaat taacaattta atattaagaa
      121 acggctcgtt cttacacggt agacttaata ccgtaagaac gagccgtttt cgttcttcag
      181 agaaagattt gacaagatta ccattggcat ccccgtttta tttggtgcct ttcacagaaa
      241 gggttggtct taattatgaa taacatcggc attactgttt atggatgtga gcaggatgag
      301 gcagatgcat tccatgctct ttcgcctcgc tttggcgtta tggcaacgat aattaacgcc
      361 aacgtgtcgg aatccaacgc caaatccgcg cctttcaatc aatgtatcag tgtgggacat
      421 aaatcagaga tttccgcctc tattcttctt gcgctgaaga gagccggtgt gaaatatatt
      481 tctacccgaa gcatcggctg caatcatata gatacaactg ctgctaagag aatgggcatc
      541 actgtcgaca atgtggcgta ctcgccggat agcgttgccg attatactat gatgctaatt
      601 cttatggcag tacgcaacgt aaaatcgatt gtgcgctctg tggaaaaaca tgatttcagg
      661 ttggacagcg accgtggcaa ggtactcagc gacatgacag ttggtgtggt gggaacgggc
      721 cagataggca aagcggttat tgagcggctg cgaggatttg gatgtaaagt gttggcttat
      781 agtcgcagcc gaagtataga ggtaaactat gtaccgtttg atgagttgct gcaaaatagc
      841 gatatcgtta cgcttcatgt gccgctcaat acggatacgc actatattat cagccacgaa
      901 caaatacaga gaatgaagca aggagcattt cttatcaata ctgggcgcgg tccacttgta
      961 gatacctatg agttggttaa agcattagaa aacgggaaac tgggcggtgc cgcattggat
     1021 gtattggaag gagaggaaga gtttttctac tctgattgca cccaaaaacc aattgataat
     1081 caatttttac ttaaacttca aagaatgcct aacgtgataa tcacaccgca tacggcctat
     1141 tataccgagc aagcgttgcg tgataccgtt gaaaaaacca ttaaaaactg tttggatttt
     1201 gaaaggagac aggagcatga atagaataaa agttgcaata ctgtttgggg gttgctcaga
     1261 ggagcatgac gtatcggtaa aatctgcaat agagatagcc gctaacatta ataaagaaaa
     1321 atacgagccg ttatacattg gaattacgaa atctggtgta tggaaaatgt gcgaaaaacc
     1381 ttgcgcggaa tgggaaaacg acaattgcta ttcagctgta ctctcgccgg ataaaaaaat
     1441 gcacggatta cttgttaaaa agaaccatga atatgaaatc aaccatgttg atgtagcatt
     1501 ttcagctttg catggcaagt caggtgaaga tggatccata caaggtctgt ttgaattgtc
     1561 cggtatccct tttgtaggct gcgatattca aagctcagca atttgtatgg acaaatcgtt
     1621 gacatacatc gttgcgaaaa atgctgggat agctactccc gccttttggg ttattaataa
     1681 agatgatagg ccggtggcag ctacgtttac ctatcctgtt tttgttaagc cggcgcgttc
     1741 aggctcatcc ttcggtgtga aaaaagtcaa tagcgcggac gaattggact acgcaattga
     1801 atcggcaaga caatatgaca gcaaaatctt aattgagcag gctgtttcgg gctgtgaggt
     1861 cggttgtgcg gtattgggaa acagtgccgc gttagttgtt ggcgaggtgg accaaatcag
     1921 gctgcagtac ggaatctttc gtattcatca ggaagtcgag ccggaaaaag gctctgaaaa
     1981 cgcagttata accgttcccg cagacctttc agcagaggag cgaggacgga tacaggaaac
     2041 ggcaaaaaaa atatataaag cgctcggctg tagaggtcta gcccgtgtgg atatgttttt
     2101 acaagataac ggccgcattg tactgaacga agtcaatact ctgcccggtt tcacgtcata
     2161 cagtcgttat ccccgtatga tggccgctgc aggtattgca cttcccgaac tgattgaccg
     2221 cttgatcgta ttagcgttaa aggggtgata agcatggaaa taggatttac ttttttagat
     2281 gaaatagtac acggtgttcg ttgggacgct aaatatgcca cttgggataa tttcaccgga
     2341 aaaccggttg acggttatga agtaaatcgc attgtaggga catacgagtt ggctgaatcg
     2401 cttttgaagg caaaagaact ggctgctacc caagggtacg gattgcttct atgggacggt
     2461 taccgtccta agcgtgctgt aaactgtttt atgcaatggg ctgcacagcc ggaaaataac
     2521 ctgacaaagg aaagttatta tcccaatatt gaccgaactg agatgatttc aaaaggatac
     2581 gtggcttcaa aatcaagcca tagccgcggc agtgccattg atcttacgct ttatcgatta
     2641 gacacgggtg agcttgtacc aatggggagc cgatttgatt ttatggatga acgctctcat
     2701 catgcggcaa atggaatatc atgcaatgaa gcgcaaaatc gcagacgttt gcgctccatc
     2761 atggaaaaca gtgggtttga agcatatagc ctcgaatggt ggcactatgt attaagagac
     2821 gaaccatacc ccaatagcta ttttgatttc cccgttaaat aaacttttaa ccgttgcacg
     2881 gacaaactat ataagctaac tctttcggca ggaaacccga cgtatgtaac tggttcttag
     2941 ggaatttata tatagtagat agtattgaag atgtaaggca gagcgatatt gcggtcatta
     3001 tctgcgtgcg ctgcggcaag atagcctgat aataagactg atcgcataga ggggtggtat
     3061 ttcacaccgc ccatt
//
LOCUS       DAFKHN010000162         3056 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFKHN010000162 DAFKHN010000000
VERSION     DAFKHN010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.169"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..290)
                     /locus_tag="LY912_002884"
     CDS             complement(<1..290)
                     /locus_tag="LY912_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HBM6956491.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSV"
     gene            440..922
                     /locus_tag="LY912_002885"
     CDS             440..922
                     /locus_tag="LY912_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBM6956492.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            959..1969
                     /locus_tag="LY912_002886"
     CDS             959..1969
                     /locus_tag="LY912_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBM6956493.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(2084..2797)
                     /locus_tag="LY912_002887"
     CDS             complement(2084..2797)
                     /locus_tag="LY912_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956494.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
     gene            2947..>3056
                     /locus_tag="LY912_002888"
     CDS             2947..>3056
                     /locus_tag="LY912_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956495.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT         1038 a          497 c          609 g          912 t
ORIGIN      
        1 acacttttcc aaggaacttt gatgacgtta tccgtatata cgtagcctgc ttcttggata
       61 tttttttcaa gggcacgaat cgctgctttt tccggtgcga tagaaaaatg atttttagca
      121 aaactaaatg caataataaa ggtaccatgg tcagtaaaca taggttggtt ccattttaca
      181 gttgtgtcta gctggggata cgtttctgtt atcttagcaa aaaggtcttt gatcttttgt
      241 tgatgttctt tttctttgat ctgattgatg atcggctgaa atttttccat tctaaaacgc
      301 ctccattaag tggtttgatt tattttacca gaaaaacaat agttatgtat aaaaaacgaa
      361 caaaacacaa gtaatgttgt aaccgctata tttatatgat aagatgtctc aaataataaa
      421 atagaaaaga gacataaaaa tgattgactt ggcaaagaaa ttcttacacg aaaatatata
      481 ttttgagttg tatcatcatc gagccattta tacaaatgaa gatgctttgg taataaagaa
      541 agaacaagga tttacaggta cagagaccaa aagcttattc ttaaaagata aaaaagataa
      601 taactacgta tatctgactt ttactacgaa acaaacggat ttcaaagcat tagggaagat
      661 cgtcggtaaa aggctttcta ttgtttcatc agaacgcatg gaagaacaaa cgggacaaaa
      721 gcagggcgct gtttctccgt ttggttatga aaaacagatt ccgattatta ttgatgaaga
      781 gctcttatca aatgaaaaac ttgtttttgc accaggtaga ccagatcaaa cgatggtcat
      841 ccaaacggtt gacttaaaca aaatcatcca gctacttgag atgccgatat ttttgatgcc
      901 ggcaaacgaa aaaaacaatt aaccaagtaa aatagtgcat acttggaggt gaagcaacat
      961 gataagttat ccattattag aaagaaatgc aacgattggg gttactgcac catcctcagg
     1021 cgtatcagag gaacaccatt cgttactcga atcagcttta aagagaatgg aagaaaaatc
     1081 tttccaagta gttactggaa agacgctttg gacgcaagat aaggaaaaat caggtccagc
     1141 aagaaaacga gcagatgaat tcaatcaaat gatgcaagat gaaaatatcc aaatgatctt
     1201 tccgccttgg ggaggagaat tattgattga gattctcgat tttgtcgatt ttgatgctct
     1261 acaaccaaaa tggatagtag gttattcaga tattagtacg ttgctacttg ctgtcacatt
     1321 aaaaacaggg atagccactg cacatggaac caaccttatt gatttaagag gagagtactt
     1381 ggatgaaacg acagcaatgt gggaaagtgt actgaaaaca agagaaggag aatcgattct
     1441 acagcaacct tctgaaaagt atcaaaaaga gtggccccat gagcattcat catcttctgt
     1501 tttccatctc actgaaccaa caaattggca atcagtcagc ggagatgcag taaggatgaa
     1561 gggacgatta ttaggtggct gtattgatac gatcagtcat ttaatcggta ccccttatgg
     1621 agatgtccaa tcttttaaaa gaaagtataa tgatggaaag ccgatcttgt ggtttctaga
     1681 aaattgtgag ctatcgtcag ttgatttaag aagatcactt gttcagatga aactggcagg
     1741 atggtttgat ggcagctcgg ggatcatgtt cggtagaagt gcagcagagg atttgttaga
     1801 ttataaaatg aaggatgtat atgaagatct gtcaaaggaa ttaaaactac cgatcttgta
     1861 tgatattgat tgtggtcatg taccgccaca actgacattg atcaatggtg cctatgcaga
     1921 agtagcggta gaagatagaa aagcgactgt tttgcaaacg tttatttaaa aaattttttc
     1981 ctgccttgga gtttatcaaa gaccaacaaa tctaaataga aaagaaaatg aaagaagctg
     2041 acagtatttt gccagcttct ttttgtatga tctattagaa attttaatta tccataacta
     2101 tcacattgat cagctgtttc acatcatttg gattacctgt aggaatagct actacagatg
     2161 cattatcaat aatttcttga gttgtttctc taatgaacgc tggataagat gtttgatctg
     2221 caggcatttg ccaatgtgaa ggaactggat aactagtgat tgtcccgtca tggttacttg
     2281 aatacactaa aactccctgg taactgtatt tcccagtgag cataaccaca tctttcggat
     2341 agactgcact ccctgcatca taaggggcga taggtgttcc tgcaggataa tgaataacat
     2401 gtagttcgaa atcacccgat gtatctctaa aagtattacc tctaattgct agccaaacac
     2461 gtgcgtactc aatttgtaga tcagaatatc ctgctaacgg atctattgac tgagaagact
     2521 gtgaggaagt tgtgtctatt gttgaagaag aaatatttgt ctcaactgta ctactagatg
     2581 tagaagaagt attgggctct gagactttac tgcttgttga agatgtattc gtttcagtag
     2641 aagctgattt ctgagtactt gatttttcag ctgaactggt ttgtttgatt gaacttttgt
     2701 ctgtggtcgc agatggatca ctattttctt tactaggaga cgtacatcct acaaggaata
     2761 aagagaccaa caataaaata aaacctaact ttttcatata aaatacctca ttattttttt
     2821 aataccagta tagcataatc ctgaattttt gaatccgtaa aaccttgtct atggataggc
     2881 tacaattaac tagacagaaa aattaaggtg tgtagactag aagaaaacat accaggagga
     2941 atttttatgt ctaagagaac acgaagaact ttttcacaag aattcaagca acaaatcgtc
     3001 aatctttact tagctggaaa gccacgtgta gaaatcattc gagaatatga actaac
//
LOCUS       DAFKHN010000163         3048 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFKHN010000163 DAFKHN010000000
VERSION     DAFKHN010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.170"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            99..569
                     /locus_tag="LY912_002889"
     CDS             99..569
                     /locus_tag="LY912_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBM6956496.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            791..1894
                     /locus_tag="LY912_002890"
     CDS             791..1894
                     /locus_tag="LY912_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBM6956497.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            2115..>3048
                     /locus_tag="LY912_002891"
     CDS             2115..>3048
                     /locus_tag="LY912_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBM6956498.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVT"
BASE COUNT         1057 a          515 c          653 g          823 t
ORIGIN      
        1 aatctctgaa gaataaatca cgtgatcgtg acgataaaat acacttacgt caggtgataa
       61 aaaatacata agtagaaaac taagaggagg aacagaaaat gaaagaagtt caattgatca
      121 gaaaaagcga actatcagaa ggtggttgca atgcatgcgg cgtagtagaa gcaacaagct
      181 atacattaaa gcttggtgcc aacaaagcga taatctctga gttgacagta ggcggtcttg
      241 tggacagtct ggcgcttgct gaaggtttta ttggagaaga tatttatgag atgttttcag
      301 aaatccgtca gttaaaaaaa ggggaaaact gcatagaggt tcatcatgag agcccgaatg
      361 tgagattcaa acgtggtgat aatgagatga tcttcaataa tcatgtgtcc gatcacaccg
      421 agctatatgg aatcgtgaat caaatactaa ctgagctttt tggattggga ccttatgcgt
      481 tcaaggaaga aaacggtaat ccaaaattaa acgaagaatg gcaagaaacg attgaaatac
      541 aaagaaacaa cccgcactta tttcaatagg catccacagt atttcgtaaa agggactttg
      601 acacgacttt tgtcaaaatc ccatcgtttt ttatctattt gtgttctaaa catttctttc
      661 agagtagtaa caactggaat gactgaaatg taaacagatt atttgcctgt atcaatacgg
      721 aagagtaata taaagtgtgt aaacgctatc atattattca ttcaattttt tatagaggga
      781 aggcattgaa atggaaaaaa cgtatcaagc aggtacaaat gaaggaatag tggattttat
      841 caatatggaa gatttagaaa tagccgcttc acaagtgatt ccagctggtg gttatggtta
      901 catcagcagt ggtgctggcg acttatttac ttatcaagaa aatgaacggg cattcaatca
      961 tcagctgatt attcctcatg tattaagaga tgtagaatta cccgatacaa ctacacattt
     1021 tgacaaagaa acgctgactg caccaatcat catggcacca gttgctgctc atggcttagc
     1081 tcatgtgaag gcggagaaag cttctgcaaa aggtgtagca gattttggga cgatctatac
     1141 agcaagttct tacgcttctt gtacattaga agagataaga gaagcaggcg gggagaaagc
     1201 accgcaatgg tttcaatttt atatgagcaa agatgatggg atcaatttgg atattcttga
     1261 agtggccaag cgtaatggag caaaagcaat cgtattgaca gcggatgcaa cagttggcgg
     1321 aaaccgtgaa acagaccgca gaaatgggtt taccttccca ctgccaatgc cgatcgttca
     1381 ggcttatcaa tcaggagtag gccaaacgat ggatgctgtg tacaaatctt ccaaacagaa
     1441 gcttagtcca aaagatgtag aatttattgc tgctcattct gatttgccag tctatgtgaa
     1501 aggtgtccag tcagaagaag atgtctatcg ttcattagaa tctggtgctg gcggaatctg
     1561 ggtatctaat catggtggcc gtcaactaga tggtggtcca gcagcgtttg attcgttgca
     1621 atatgtggca gaagcagtag ataaacgtgt accaatcgtg tttgacagcg gtgtacgacg
     1681 cggacagcat gttttcaaag caatcgcatc aggtgcagat cttgttgcta ttggcagacc
     1741 cgttatttat ggattgtctt taggaggaag tacaggagtc catcaagtgt ttgatttctt
     1801 taaaacagaa ttggaaatgg tcatgcaatt agctggaaca caaacagtag aagatatcaa
     1861 aaaaataaaa ttgcgtgaga atcgttttat ttaagaaaca aatgacgaaa aaaataggag
     1921 tgcggcagat gatgccgtac tcctattttt atagttcaag gatgtcacta atagaataat
     1981 ttgaaacgaa aaaataaaat tgaaatattt tttcatactt cgccgattgt aaaattaagc
     2041 tagacaacta aaaaaagtca tttgtgctac actcaaaata gttccgacga aagaattata
     2101 aggagtgagt acaaatgacc tataaccatc ttacaccaac tgaactcgta atgatagaag
     2161 cttatttcaa tcaatcacaa cctgtttcaa aagtagccaa tctgttacaa cgttctcgac
     2221 aaactattta taaggtctat cgttttctta aatctggtgg aagcgcaatg agctactata
     2281 aacaatataa gaaaaacaaa cgtaactgcg gaagacatcc gattgtttta cctgatgagc
     2341 aacaggaata cattcaaaaa aaggttgttc aagggtgggc tcctgatgtc cttattggtc
     2401 gagcagagtt tcctattgct tgttcggtac gcacactgta tcgaatgttt aaagataaaa
     2461 cctttgacac tcacgattta ccaatgaagg gaaaaagaaa accaaacggt cataaagaaa
     2521 aaagaggaaa acaagggttt cgccggtcaa tccgagacag aaagacagac tatacccagt
     2581 ttgatcatga atttggtcac ctggaaggtg acactatcgt gggtggaaaa cataaaagcg
     2641 cggtcatcac attagttgaa cggctatcta aagtcatcat taccttgaaa cccgaaggca
     2701 gacaggctaa agacattgaa aataggctga atcaatggtt tcgttgtgtc ccaaaaaact
     2761 tatttaaatc catcacattt gattgtggaa aagaattctc aaattggaaa aagattagta
     2821 ataccaacga tatttcaatt tattttgcgg atccaggaac accttctcaa cgaggattga
     2881 atgaacattc aaatggctta ttacgtaaag atggtttgta taaagctatg gattttaatg
     2941 gtgtatctga aacctttatc caatcggtgg catcgaaacg aaatcatatt cctagaaaat
     3001 cattacacta tcggacacca atggaagtat ttttgagtta cgtcacaa
//
LOCUS       DAFKHN010000164         3012 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFKHN010000164 DAFKHN010000000
VERSION     DAFKHN010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.171"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(551..2164)
                     /locus_tag="LY912_002892"
     CDS             complement(551..2164)
                     /locus_tag="LY912_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBM6956499.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNNYTSARILAGLGIKAILIEE"
     gene            complement(2305..>3012)
                     /locus_tag="LY912_002893"
     CDS             complement(2305..>3012)
                     /locus_tag="LY912_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956500.1"
                     /translation="EVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFSIDQEITSII
                     TFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCLQKIQLSSLP
                     RHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLLEQLAQIFFI
                     SPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGFHSIHHFSSA
                     FKKYTGLSPSKYYLSLK"
BASE COUNT          970 a          533 c          524 g          985 t
ORIGIN      
        1 taaataaata ggaacaaaaa aattaaatta tttaatacac acattaggga tcattcattg
       61 aaggattaga agacaacgag gatggcgaaa aatatgatta caatagaaaa gtcgttctaa
      121 accaatcagt tcctagtatc acacaacgca agccagtcga tttggtgaga ttagaggagt
      181 gaaagcaaac tttattatat aagaaaaaat attcgaaagg gatgctagtt taggtactag
      241 tgctgataga ttaatatgat gcctcgtaat attaggcgta gttactctag agacatcact
      301 atggactatg atttgtctca gagtcacaac atgttttttt atgaaaagaa acagctaaaa
      361 taattaaatt gcgcaatgtt taaactttct taaactataa cctaataaat gtgaagaaat
      421 aatgcacaat ttcttcacat ttatcttcta ttctatatac ataccaacca acaaccctat
      481 atactttttc atttttactc ctcaagtaaa aataactcct agaccgcggc tacccaccgc
      541 ggtcgttttt ttattcttca atcaaaatcg ctttgatacc caaacctgcc aagattcggg
      601 cagaagtata attattcaat cctcttctga aagtaatgta aactttttta tcttttggga
      661 tttcattgat tcgatctcgt aactcattca ttggaatatt ttttgttgcc gagatactgc
      721 cagaaggtgc tttattaggt tcacgtatat ctaaaaagaa cgcttctttc aaatcgtttt
      781 cgggtatatc acttgctttg atcgtttcta cgatattcgt catttgattg attgcgacat
      841 aaccagctat attcaacggg tcacgggtag tagaatacgg tggagagtaa ggcaactcca
      901 aatcaggcaa atcaaagact gtcaagtttc cggtgattgc tacagaaagt tctcccatcc
      961 gtttatcgac acctttttct ccaaatgctt gtccacctaa aatacgaccg ctatctgcat
     1021 caaaaatcag ctttagattt aatcttgtag cttctggata gaaataggca tggtcaaagg
     1081 gagtgataaa aacagtttta taatttgtta tgcctgatgc ttttaattca tgttctgtca
     1141 ttcccgcata acttgctgta tgatcaaaga tttttgcgac acctgcacca atatatccgc
     1201 gatagcgcat aggcgtacca tttaaaatat ctgccagcat atgtccttga cgattggccg
     1261 cactggaaag catactttgg atcggctgac cagtcactac actagtcgtt tcgataatat
     1321 cgccaatcgc atagatgtcc ggcagattgg tttgtaactg gtcatcaaca atgatctgac
     1381 ctgtatctga taattgtatg ccggttgctt tcaccacttc attcttcgga gaaacaccaa
     1441 cagcaaaaat tagcatatca gcagaaagga cggagccatc tgataatact atttctcgac
     1501 ctttatcacg gatctcagta actcttgttt ctaaatgaac ggctaatcct tctttcagca
     1561 atttgtcata aactaaatta gcaatttctg gatcataagg gaaagcgact tgtggcaatt
     1621 gatcgattaa agtcacgtct aagccgcgat gcttgaaatt ctcagctaat tccagaccca
     1681 taacacctgc accaagaatg acgacatgtt gtggattttt ttcttcaagg aacgatttga
     1741 ttcgatccgc atccgtcaca ctacggagga caaagccgtt ttctgcttca aaaactccgg
     1801 gaatatccgg ataatctggt ctagcaccag aagagatgat caacttatcg taatctgttt
     1861 ttatttcttc atttgtggat aggtctttaa ctgttaatcg cttagtagaa ggatcgattg
     1921 ctgttacttc gtgtttagta aagacatcga tgttgttttt tgttttcaat atttctggtg
     1981 tacgttcgat cagcgagtca cggtcagtga tcacacctcc taaataataa ggcaaagcac
     2041 aacttgcata agaaatattt tctccgcgtt catagataat gatttcgtgc gcttcattca
     2101 atcgacggaa acgagtggca aatgaaggac cgccagctac accgccaatg acaacaactt
     2161 tcataaaaac atctcctttt ctacgttgat cgtactatgt tatggtaaaa aacagcaaat
     2221 aattgtgccg gaaaattatt gtttattttg aatagacaga aaatatagag aaataatttg
     2281 tggataaaac ctaaaaattt ttttctattt taaggataga taatactttg aaggggataa
     2341 ccctgtatat tttttaaaag ctgaagaaaa atgatggatc gaatgaaatc ctaatatatc
     2401 tgcaatttct gtataggtta attcattttc tagcacgaga cgttttgctt tttccatttt
     2461 tagttcttta aaatagctaa taacactttt tccattcact tttctaaaat gtttttttaa
     2521 gctggctgga ctgataaaaa aaatttgggc taattgttca agcaaaaaat tttctgaaag
     2581 atgttcttct aaatatcgta tgattggatc aactaattca tctgaataaa gaatatgctt
     2641 ttttttagga atgactttct catttgaagg tattgtcaat aaagcaagtt cctgttgata
     2701 atgccttggt aaggaagaca attgaatttt ttgcagacaa taagtaacta ataaggaaag
     2761 caaatgaatg ctcatctgtt ggcatagtat gaaaaaagaa ttgatttcct gatcatagga
     2821 aatagctggc ttactatgtt ttagataatc aattttgaac tgttcatttt tcagaaaagt
     2881 aatgatagat gttatttctt gatctataga aaaagattgt cccgtaatat gtgctaataa
     2941 ttgctcatca aaataaaact ggataatgat aaaagtttgt gtttcctttt gagtagaaaa
     3001 gatttggact tc
//
LOCUS       DAFKHN010000165         2963 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFKHN010000165 DAFKHN010000000
VERSION     DAFKHN010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.172"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(37..1257)
                     /locus_tag="LY912_002894"
     CDS             complement(37..1257)
                     /locus_tag="LY912_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBM6956501.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1888)
                     /locus_tag="LY912_002895"
     CDS             complement(1277..1888)
                     /locus_tag="LY912_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBM6956502.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="LY912_002896"
     CDS             complement(1931..2863)
                     /locus_tag="LY912_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBM6956503.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
BASE COUNT          810 a          620 c          515 g         1018 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttg
//
LOCUS       DAFKHN010000166         2943 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFKHN010000166 DAFKHN010000000
VERSION     DAFKHN010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.173"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            557..>2943
                     /gene="esp"
                     /locus_tag="LY912_002897"
     CDS             557..>2943
                     /gene="esp"
                     /locus_tag="LY912_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBM6956504.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVS"
BASE COUNT         1065 a          450 c          583 g          845 t
ORIGIN      
        1 tcaataattt aatgaggctg tgacaaatgt cattttttgt ttcgctaaaa acgagtgaaa
       61 aaatgttgat aactccaatc attcgtttaa gattctagga atcattcaga aatgctgtga
      121 aaccgatact ttataattat aaagaaggtg atttcaaatt ccgaagaagg aatttgaagt
      181 caccttttta cttatgtcac agtctcattc agtaatgcgg gataaggctc cttattccgt
      241 tatttgaata ctctgaagtt taatctaaga aagggtaata ttttgaaaac atgcttcatc
      301 gcatagaaat gaacttaatt tcagaaagaa tacatacata tctttttata tgttttcagc
      361 tgctgaatgg ttaaaaagca caaatatccg aaaaaaacat gaagaaatgt actttttttg
      421 ttgtaatgtt catgaaattc tctaagtaaa ttagttaaca taaggttagt aagattccta
      481 ttctgtgaat aatacgcatc agatttatct tttattctta ctaggaaagt aattattaag
      541 ggagttgatt tgaataatgg ttagcaagaa taataagaga gtatttctag aaaaaacaaa
      601 gaaacgagta ttgaagtaca gtatcaaaaa attaagtgtt ggggttgcat ctgttttgat
      661 tggtgttggt cttgtcttgg gaacaactga actagttaaa gcacaagatg aaatttctcc
      721 aagcagccca cttgaaacag cgataagctc cgtacaagta ggtgacaaag tagcttcggg
      781 gaatactttt caggagaatc ctggttatac gaaaaattat aacttttcgg atttacaatt
      841 tagtcctcaa gaactaactg gagacacact aaaaggcaat acaattggat ttgaagttta
      901 cggaaaacat aatattgcag catcaactaa aaactgggaa atccgtcttc aattagatga
      961 acgattagct aaatatgtag aaaaaattca ggtcgatcca aagaaaggaa ttggatcttc
     1021 tagacggacc tttgtaagaa ttaatgattc gctgggtaga cctacaaata tttggaaggt
     1081 caattatatt cgtgcaagtg atggattatt tgctggggca gaaacaaccg atacgcaaac
     1141 cgctcctaat ggggtaatta cgtttgaaaa gagcctagat gaaattttta aagagatagg
     1201 catagacaat ctcaagaccg atcgtttaat gtatcgaatc tacttggtaa gtcatcaaga
     1261 cgatgataaa attgtaccgg gtattgatag tacgggctac tttttaacag attcagatga
     1321 tttctataat agcttagatg tatctgaaaa taatcctgac cagtttaaac atggatcagt
     1381 aagtgcaaaa tatgagaaac ctaatactca aacaaaagat ggttcaggat ccacaggtgc
     1441 taatggagct ataatcttag atcataagtt aacgaaaaat tataatttct catattcatc
     1501 ttccgcaaag ggcacgcctt ggtatgctaa ttacaaaatt gatgaacgat tagttccata
     1561 tgtagcgggt atacagatgc acatggttca ggctgacaaa gtaacatatg atgtttcgtt
     1621 tgaatccgga acaaaagtag ctgatttagc aatcgagcga cgggaaggtc atgaaaatta
     1681 tggcataggt tcaataacta ataatgattt aactaaactt atcgattttg ctaatgcaag
     1741 tccacgtcca gtcgttattc gatatgtttt acaattgact aagccattag atgaaatctt
     1801 agaagatatg aaagcaacag cacaagttga agaaaataaa ccatttggtg aagatttcat
     1861 ctttgattct tggttgtcgg atacgaataa aaaattaatc cagaacactt atggaacagg
     1921 ttattattat ttgcaagata ttgatggtga tggaaaccct gacgataaag aagagagcgg
     1981 agacacgaat ccatatatcg ggaaacctga attagaagaa gtatatgatg ttgacacaac
     2041 agttaagggg aaagtattca tccacgagtt agcgggaaca ggtcacaaag cccaacttgt
     2101 tgataaagaa ggtactgtat tagcagaaaa aactatcgct ccaaatgaaa aagatggggc
     2161 tccaatttca gatactgtag aatttgaatt tacgggtgta gattcaagta aattaatcgc
     2221 gaaagatgaa ttaaaaatcc aaatcgtttc tccaggtttt gataaaccag aagaaggttc
     2281 aaccgttatt aaggaatcac caaaagcggt tgataaacaa accgtggtag ttggatttaa
     2341 accagatgct aaagaatcaa ttcggaataa taaaaactta cctgaagatg cagagtattc
     2401 atggaaaaca gagcctgata cttctaacgt tactgatagt acgaaaggta ttgtaactgt
     2461 taagatcgga aatcgaactt tcgacgtgga tgtagagttt gctgtaaaag cttctcaagc
     2521 tatggaaaat gatgcaacat acgtacctat aacaacaact ccagaaacga cagttcaaag
     2581 tggaaaacct acatttgata aaccagatgt tcctttagct aaagatgcct tttcaatttc
     2641 agatgtctat aataagtact tcggtaatgc aagtgttgat gcaaacactg gtattgttac
     2701 attcactcca gctaaaggtg taggagaatc ggagccgatt actggaacaa ttcctattaa
     2761 aattgtttac caagatggtt ctgtaggcac gaccgattta gcagtaactg taagtaaaga
     2821 tatttatgaa aatccaggag aaaacattcc tgcaggctac cacaaagtaa ccttcaccgc
     2881 aggggaagga acaagtattg aaagtggaac aacagtcttt gcagtgaaag acggcgtaag
     2941 ctt
//
LOCUS       DAFKHN010000167         2935 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFKHN010000167 DAFKHN010000000
VERSION     DAFKHN010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.174"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            204..1595
                     /locus_tag="LY912_002898"
     CDS             204..1595
                     /locus_tag="LY912_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBM6956505.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAESAFPKEKTYR"
     gene            1633..2463
                     /locus_tag="LY912_002899"
     CDS             1633..2463
                     /locus_tag="LY912_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBM6956506.1"
                     /translation="MENKNISILLSLYDKEKPEYLKEALASIFEQTVMPAEIVLVYDG
                     PINEKLQAVVTYFQQKVPHLFTVVKLEKNQGLGIALATGLEHTKNRLVARMDTDDIME
                     PHRLEKQLEIFQEYPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFN
                     HMTVMFDKNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYAR
                     RGGSKYLLPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN
                     "
     gene            2435..>2935
                     /locus_tag="LY912_002900"
     CDS             2435..>2935
                     /locus_tag="LY912_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBM6956507.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLRRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNYGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNHPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNK"
BASE COUNT         1020 a          424 c          579 g          912 t
ORIGIN      
        1 gcaggagaat actagttcag cataaaggaa gtgatgggac ttctgagaca actttctgtt
       61 atgcagaaat acacatataa acagacaata aacgcttttc cccgtttctt ttaatttcct
      121 ttacaatttg gttattcact aggtttttaa actttgctat ggtaagatga tagaggcatt
      181 attttatggt taggagtgta tatatgaata aaaatgggga gtggaatgcg gcacgcagaa
      241 tattcattat tcttatggat gtacttgtat taaatgtatc gatctatctt agttttttgc
      301 tgaaattcca gggagaagta ccagtgagaa acttagaaac ctttcagcat tcagcaattt
      361 ttatttccat catctttatt gcgttgaata ttttgttagg agcttatgta ttctataacc
      421 gaatgatcag tgatattgtc ttcattactg ttattggaca agtactaata gcattgggga
      481 tcatggtagt tacttttgct ggccgatggt ttgcatttcc gcgtggcgtc attttgatct
      541 cgtttatcct aggtacgata ttacttagtg tttaccggat agtcgtttac aaactgtact
      601 taagagtcag tcgtgataag aaagtcctta tcgtgggttt ggagaaagat gtcgcaccag
      661 ctatccaaaa ttttcaatct aagaaaaaca ataaacataa ggttgaagca gtggcaatcg
      721 ataattatta cgaaaataca aaaaaattga tcgatgatat ggatatcgtc tatttggctt
      781 ctaaaatccc agaagatgaa aaaatcaaca tttatcaatt agtgactaaa aaagagaaga
      841 aattattttt aaatacgact tttgagaatc tgacaatgat aaatccgaat attatgaatt
      901 ttgaagatga aagcatcatt gaagcttctg ggttcagaat ccaaccagaa tacgaactat
      961 tcaagcgtct ctttgatatc atcgtttcgc ttattttact gatcctcgcc tcacctttta
     1021 tgctaatcac agcgattttg gtaaaaacaa cttcacctgg accaatcatc tataaacaag
     1081 tacgtattac gaaaaatcaa aaggaatttt caatctataa attccgttcc atgagtgcga
     1141 cagctgaagc aaaatcagga ccagtcttgg ctaaaagtaa cgatgcacgt gtgacaccag
     1201 taggtaaatt tatccgtgct gtacgttttg acgaattacc tcaaatcttt aatgtattga
     1261 aaggcgatat gtcgattgtc ggtccaaggc cagaaagacc atttttcgtt gatcagttca
     1321 atgaagaaaa tccttattat tacttaagac acaatgtacg tgcgggaatt accggatatg
     1381 cacaagtata cggaaaatat gtatcagatt ataacagtaa actacgtttt gatttgttgt
     1441 atatcaaaaa gtattcctta ctattagatt tgaagatttt acttcaaaca atcaaaatct
     1501 tatttgataa gatgtcctca caaggactag atgaagatga aaatatcagt tcattagcag
     1561 aaagtgcatt tccaaaagaa aaaacgtatc gttagattgg aaaaattttg agcaaagaag
     1621 taggagagaa cattggaaaa taaaaatata agtatactgc tttctttgta tgataaagaa
     1681 aagccggaat atttaaagga agcattagct agtatctttg agcaaacggt gatgccggca
     1741 gaaatcgtat tggtttatga tggccctata aatgagaagc ttcaggcagt tgtcacttat
     1801 ttccagcaaa aagttcctca cttgtttaca gttgtaaaat tagaaaaaaa tcaaggattg
     1861 gggattgctt tagcaactgg attagaacat actaaaaatc gcttagtggc cagaatggat
     1921 acagatgaca tcatggaacc acacagattg gaaaaacaat tagagatctt ccaagaatat
     1981 ccagaaatag cgattgttgg gagtaatatt gaagaattta ctggcacact tagcaatgtt
     2041 atcggaagaa ggattgtacc tgagtataat gatgaaatcc gtgtgttttc gaaaagaaga
     2101 aaccctttta atcatatgac agtcatgttt gataaaaatg ctattttaga agtgggaaac
     2161 tatcgcccat taattggatt tgaagattat tatttgtggg taagactatt gaaggcggga
     2221 tataaaggat ataatatcca agagattcta gtacatgcta gagcaggtgc tgacatgtat
     2281 gctagacgtg gaggaagtaa atatctttta ccaggaatta aaggccgata tcgcgtatgg
     2341 aaagatggtc taggatcact aaaagatttt ctgatagtta tttgcggaca tcttgtaatt
     2401 agtttattac cgaataaaat taggggaaaa gtatatgaat caaaacttag aaaaacaaac
     2461 taaactttct ataatcatac ctttttacaa tgcaaagaat actttaagaa gagctgtaga
     2521 cagcgtctta acgcaaggtt atcccaatat tgaaatcttg ttaattgatg atggatctac
     2581 agatggtagt agtgacattg gtgacgaaat tgctaatcta gagagtaaag tagcatgtta
     2641 tcacttggaa aacgctggtc catcagttgc taggaactat gggataaaag aagcaactgg
     2701 aaatttggta ggatttttag atagtgacga ttatttttta cctgattgtt ttaataatgt
     2761 tttgaaagac taccatagga atcaccccga tatcattgct tttggattaa gtaaaggaaa
     2821 aaatatagaa aatgcaaatt tatttgttcc cgaaaagaag attggttgtt caagtgaaga
     2881 agcaattgag caaatgttta gaagtaaggc agtggacttt tacgtatgga ataaa
//
LOCUS       DAFKHN010000168         2873 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFKHN010000168 DAFKHN010000000
VERSION     DAFKHN010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.175"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..461
                     /locus_tag="LY912_002901"
     CDS             <1..461
                     /locus_tag="LY912_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBM6956508.1"
                     /translation="SNAPKKMVEFINLSCPYCRQWFEESYELLEEAVQSGQLQRVIKL
                     FDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQDEWKHLSLQEVADFAVDKLKL
                     TEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDESISIEELKELIQTK"
     gene            complement(1160..1725)
                     /locus_tag="LY912_002902"
                     /pseudo
     CDS             complement(1160..1725)
                     /locus_tag="LY912_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1904..2560)
                     /locus_tag="LY912_002903"
     CDS             complement(1904..2560)
                     /locus_tag="LY912_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956509.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
BASE COUNT          940 a          611 c          402 g          920 t
ORIGIN      
        1 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
       61 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
      121 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
      181 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
      241 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
      301 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
      361 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
      421 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
      481 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
      541 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
      601 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
      661 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
      721 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
      781 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
      841 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
      901 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
      961 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
     1021 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
     1081 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
     1141 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
     1201 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
     1261 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
     1321 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
     1381 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
     1441 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
     1501 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
     1561 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
     1621 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
     1681 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
     1741 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
     1801 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
     1861 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
     1921 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
     1981 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
     2041 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
     2101 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
     2161 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
     2221 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
     2281 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
     2341 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
     2401 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
     2461 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
     2521 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
     2581 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
     2641 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
     2701 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
     2761 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
     2821 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cag
//
LOCUS       DAFKHN010000169         2692 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFKHN010000169 DAFKHN010000000
VERSION     DAFKHN010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.176"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            154..417
                     /locus_tag="LY912_002904"
     CDS             154..417
                     /locus_tag="LY912_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBM6956510.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="LY912_002905"
     CDS             417..689
                     /locus_tag="LY912_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBM6956511.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="LY912_002906"
     CDS             766..1095
                     /locus_tag="LY912_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBM6956512.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1085..1371
                     /locus_tag="LY912_002907"
                     /pseudo
     CDS             1085..1371
                     /locus_tag="LY912_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            1656..2513
                     /locus_tag="LY912_002908"
     CDS             1656..2513
                     /locus_tag="LY912_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBM6956513.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            2514..>2692
                     /locus_tag="LY912_002909"
     CDS             2514..>2692
                     /locus_tag="LY912_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956514.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRG"
BASE COUNT         1003 a          358 c          541 g          790 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa acatgtcatt aagtatttaa aaagctaaaa
     1141 gagaagccat tgaaagaaaa atttttgaat ttaatttatg atgaaattgc gattgatcca
     1201 tataagggtg aacaaaaaac tggggattta tcaggtattt ggtctagtgg gttcaaatat
     1261 gcgggcacaa catatagagt agcttacgag attatagaaa acaaggttat tccagtattg
     1321 ttatgtggaa cgcatgaaaa cttttatgaa cagttgaaaa aattaatcta gtgatttgtt
     1381 gtcgttctta agaaggacgg cttctttttt atcgaaaatc tgattcgtct acatgactaa
     1441 agtcgcgagt attctctgct tctcgataaa ttaaataacg tcattacttt gaggaaagct
     1501 ataaatcaat atatttcagc ttttccttat ttatgtacta ccttttactt attaattata
     1561 aggtagtaca tatatatctt tttttggtag taactaaaaa taaatatgtt ataatagtat
     1621 caaatgaata ttgctaaaag aaaagaggta ggaacgtggt agcgaagaaa tatgtaatcg
     1681 gtaattttaa aggtggcgta ggtaaaagta cgtgcgcgca aatgttaggg tttgaatcag
     1741 cagttaatga aggaaaaaga accttgataa ttgacttgga tatgcaagga aatacttctg
     1801 atgtgatgaa cttaacgcat atgaacttca ctaacgaaga aggaggcgga gaaggtgaac
     1861 cgattgttta cgaaaatact gtgactgacg tgttgataaa caatcttcca cctaaagagg
     1921 ctgtctataa agtaatcaat aacctctata tacttccagc agacatgtcc tttgaaatgt
     1981 atgatgattg gatcaaagac caatataatg attcattatc ccaattcaaa tatatgaaag
     2041 aaaagctaga accattattt gatgagtttg acgtcatcta tttagatgtc ccaccttcta
     2101 tttctgtata tagtaaatcc gcgatgtaca ttgcggattg ggcaatcgtc gtcttacaga
     2161 cccaagtaaa atcgatgaga aatgcgatgc aatatcttga gtatatggac ttttttgtga
     2221 aagaatttga tacaaattta tatgttgctg gtgttattcc tttcatgttg gaaagcggtg
     2281 acgcagtaga tcaggaaatg tataaacaag cccaagagat ttatggggaa catttgatta
     2341 aaaatgttgt actcaaaaat gcgcgcttaa aacgatacga cggatcaggt attacgatgg
     2401 agaagacaaa gaaaggtctc ttaaaacaat gggatcgcaa aagccacgaa ttatttatca
     2461 gtattttgaa agaattggaa gaacacgaga attggtatgc ggaggtggag taattggctg
     2521 acatcaaagg acttgatatt tttgggaaca acaaaggact cgccaaaata aaaaaagaag
     2581 cagaagcaaa gaaaaagcag caagcaatta caccatctga aaataagcaa ttagaagtgc
     2641 accaagttca agaaataaaa acttcctcca atgttgaaag acagagtaga gg
//
LOCUS       DAFKHN010000170         2689 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFKHN010000170 DAFKHN010000000
VERSION     DAFKHN010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.177"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            172..2544
                     /locus_tag="LY912_002910"
     CDS             172..2544
                     /locus_tag="LY912_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956515.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VREIEATPEDKKRIESGQIEVIKKTYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTLEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
BASE COUNT         1074 a          423 c          580 g          612 t
ORIGIN      
        1 gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga gaaatcacac
       61 aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa tctagaaaca
      121 ttttgaataa aaactattag acaaatgata ttttacgagg aggaaacgga catggcagaa
      181 gaaaaagaac cactagacaa tagtcgcttg ggaaaatcca aaagaaaatt agtacgattg
      241 caaaatgaat taaacgaaca aattgagaag atgtttgaac accagagaaa gaccaacggt
      301 cagccaatga acgataagag aaatgggcat tcttggttta ggcaacaaga acgtttagaa
      361 aacaaagtgc atagtctgag agaagagatc aagcaacaag aaaaacaggt agaaaaactt
      421 gaaagacaag aagagctaaa ggaaatgggc tataacaagt acggcggact ggatatgacg
      481 atcgataata ttccaagaat caaagaagaa atcgaacgct ttgaaaaagg tgaatcgact
      541 ttttcagccg ccacgatccg aaaatatcaa cggaagttgg aaacattaga acagctgaaa
      601 gaaaaatcag aaaaaggaaa agaaaatatc ctccctgaag tacaagcgat cattgacagc
      661 ggacgagtga cgcaatggaa aaaaaatcca accatttatt ttttgaaagg ctatcgaaaa
      721 gttgctttag aactgaatga aaacggggga tttgaggaat caaaaaaata ccaagccacg
      781 tcggaagagg aaaaagcagc tgttcgtgaa ttacttgaag aggctgcacc aactgattct
      841 ctgaaggaga aagaaaaaga tcatttctat cgagtagaat tcaacgaaaa tgatccagaa
      901 aaaggattga aaagttatgg tggggagatc gtaacattag aattgatcga tcaacttaaa
      961 acgttggata accaatacgc tgcagaagca ggttattata aattctattt tgaagaagtg
     1021 aagaacggag aagtagtaga tcagatccga atggatctag gggatggcgt caacagtaat
     1081 caccccatct atttagagtt agcaaaattg tgcgaacaag tacctgagaa ggaacaaaaa
     1141 caatcggtca aaaatgaacc tgtttcgaaa gaacaaatgc agtcgaaaga aacaaaaaca
     1201 aaacaaaagg gctatcaaaa acgaacggca gaagagatta aacaagaagt taaatccctt
     1261 tcgcaacagg cactggatgc ggtgaaaaag catactcatt ctcctgaaga cgtcaaagaa
     1321 cttttgaact ttatgtctcg ttttccagaa cgatccttta gaaatcaatt attgattgag
     1381 gaacaatttc caggtgcaac ggcttgttta ggtcgtgccg cgttgaaaaa agaaggaatc
     1441 tatatcaaaa aaggggaaca agggaacaag atctttgtca gaaaaacggt caaaggattt
     1501 tatgagaaag gacgtggctt tgttcgagaa atagaagcta caccagaaga taaaaaacga
     1561 atcgaaagtg gtcaaatcga agtgatcaaa aaaacttact acacgattga aaaagtgttt
     1621 gatatcacac aaacacagtt aaaacctgaa gactatccga aaatctttcc gaaccgtgtc
     1681 tttgattttc aattggataa aaaaggacag tcagaacttc aagctgggat tcaagcggta
     1741 gccaacaata ttggaataca aattcgagat atgacagaaa gtgaagtcta tcaaagagaa
     1801 ttaggacaag cacgtggggc gtatgttcgt aacgaattta ctggcgaaga agaaatcgtc
     1861 atgaatactc gaaatactcc tacgcagcat ttagctacaa gtattcatga attagcccat
     1921 gcaagaatgc acaaattttc agaattagat accgcaacta aagaattgca ggcagaaatg
     1981 acttcttata ttgtgtgcaa acattttgga atggacacgt tggagaaagc tattccttat
     2041 attgcagcat ggacgaagaa tggtcagacg ttggatgata aggaagctgc ggaacgtggg
     2101 aaaatcatga atgatgtcag ccgtgtcgca aatgaattca ttcaaaccat ttctaatgaa
     2161 atcaatcaat acagagaaag agaaccagag atccaaccag cagaagtgaa gcaggagcat
     2221 aaaaatactg tagaaacggc agaacaaaag aatattgttc ctgttggttc actttggatc
     2281 gacaagaaag acgggaaagt aatggaagaa gatacgggtc gaacgttaca tttgaaggat
     2341 gcggcgttta ttgaagatcc acagcataat caagtaattt taaaaggaaa aagttatgga
     2401 aaagagatcc aaacggcgtt accttcagaa gaatttgcgc taggaaattc attccgattt
     2461 tcacttgaga cagtgtcaga agtggccaaa cgaaaaaatg aaatctatta tgaacaacaa
     2521 ttgtcacaaa aagaacgtgt ataaaacaag taaaaaagac tatctgaaaa acggatagtc
     2581 ttttttcttt tgggaggttt taaaatgacc gagaaaaaaa tgagtcttat tgatcgatgt
     2641 aaacagatcg atatagtgga ttttgctcga aacaatggaa tggctgtag
//
LOCUS       DAFKHN010000171         2647 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFKHN010000171 DAFKHN010000000
VERSION     DAFKHN010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.178"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1350
                     /locus_tag="LY912_002911"
     CDS             <1..1350
                     /locus_tag="LY912_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBM6956516.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..>2647
                     /locus_tag="LY912_002912"
     CDS             1484..>2647
                     /locus_tag="LY912_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBM6956517.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIV"
BASE COUNT         1044 a          363 c          523 g          717 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagta
//
LOCUS       DAFKHN010000172         2406 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFKHN010000172 DAFKHN010000000
VERSION     DAFKHN010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.179"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..103)
                     /locus_tag="LY912_002913"
     CDS             complement(<1..103)
                     /locus_tag="LY912_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBM6956518.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQEL"
     gene            complement(177..458)
                     /locus_tag="LY912_002914"
                     /pseudo
     CDS             complement(177..458)
                     /locus_tag="LY912_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
     gene            920..2302
                     /locus_tag="LY912_002915"
                     /pseudo
     CDS             920..2302
                     /locus_tag="LY912_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          875 a          412 c          400 g          719 t
ORIGIN      
        1 acaattcctg aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa
       61 taatgacgtc ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt
      121 cttttttctc aattttacac taaaatagat tttttggaaa actttgcaac agaaccgaaa
      181 tgagtatagt atgaattagt aatttggttt tcatctaagt ttagctttga tttactaaaa
      241 ttgatatctc gatacatgtt caatacatct aatacaaatc gagaatcttc tttcggaaat
      301 ggctcagaaa gatcactcca aatttcatca tcataatgat actcgtaacc ttctctcaat
      361 atttcgattt ttctttcata ataagatctg ttttggtcct caaatttagc caataactca
      421 aattgattta ctagtgacaa tctctgaaaa ctgtccatta aatgtttctt cctatcttgt
      481 tcattaacaa aaaattataa gcccttacaa cgaatattat atattaaatt taattgtagg
      541 tgaacacgaa ttttataaat atttatggtg ttaatgacaa atgatatccg actcctcttc
      601 atacgttctg gactatttgc taatagatta aaatttcagc atctatttct gaccataaat
      661 aaatgagctg ccgaaaagct gccaaatcag acttgaaaat aaaggatcaa aaacttttaa
      721 gtttctgacc ccgtaactca cacttcaaaa tcttacttaa aaaggagtct gaaagaaaaa
      781 aagagtattc aaaatttttt tctaactagc tacatcacat ctatgcattg acactcaaag
      841 aaccagaata agtcatcaga aagcaagggg gtgcggacat aatcctggac gaaaaaataa
      901 acttaggagg aatgtccgtg tgttttccca caaagagcgt gtaagggcaa ttcagttatt
      961 tttaaaatac gattgctctt atgctgcaac cattcgagaa ttagggtatc cgtcgattgg
     1021 tgcactacgg aaatggtata aagagtattt ggaatccgga gagctccatc aggagcaccg
     1081 aaaaaaatca aagtattctg aagaacaaaa acgaatagcg gtgaatcatt attttgaata
     1141 tggtcaatgt tatgcacgaa ccattcgcat gcttggttat cctaatagag agtccttgcg
     1201 gcagcggtgt gaagaacttg caccaggagc tagaaaactc cgaaaaagtg cggtaaagtt
     1261 aacacaagat caaaaagaag ctgtgttgaa aaaattctat aaaccgcaaa ctaataggaa
     1321 aaatttagcc gaatctggag gaattagtag agttactcta tatcaatgga aaaacacggt
     1381 tcttggaaag gattttccat tgtgtatgac tttaaaaaat caggaaaaac aaaaagagct
     1441 acttttaaag gaagtagaag acttacaaaa acaagtacac caattacagc tcgaaaaagc
     1501 attactcgaa ggagcggctg aactgctaaa aaaagaaaaa ggcgtcaatc ttctttgtct
     1561 atcaaatcaa gaaaaaacga tattgattga tgccttacga aatcagttca ccttgaaaga
     1621 gcttcttcaa cagctccagt ttcctaaaag cagctatttt tatcaaaaac aagcacttga
     1681 gaaaccagat aagtattaca aagaacgtca aattaattat cacgattttc aatcataact
     1741 tctgtgcgta tggttaccgt agaattcacc aagctttaaa aaatatgggt aaaaagcttt
     1801 ctgaaaaagt tgtacgtaga ttgatgactg aggaaaatct atttgttaaa ttttctagac
     1861 gaaaaaagta ttcttcgtat gctggggaaa tttctcctgc acaccccaat ttattaaatc
     1921 ggaattttaa agcaaagaag ccaaatgaaa aatggttaac agatattact gaatttagaa
     1981 ttctcgcagg gaaaatctac ttatcaccac ttgtcgattg ttacgatggt gctattgtta
     2041 gttggactat tggaacaaag ccaacttgct tcactctatg tctaaaaaga gttattcacc
     2101 agataattca gcgtgcgaag gtttctttgg acgattaaaa aacgagatgt tttatcaacg
     2161 tgactggaag aatacaacaa tcaatcagtt tataaacaaa ttggatgatt atattcattg
     2221 gtataataat caacgaatta agttatcttt aggaaggcta agccctcttc aatatcggaa
     2281 gaagcaaaga tatatttgtt aaaaaggtcc aaaaaaaata tccgcacccc cttttttttg
     2341 taaaaaacta ttgcacaata caagtagcct acggctatcg aaatttccat aactttcgag
     2401 caagaa
//
LOCUS       DAFKHN010000173         2356 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFKHN010000173 DAFKHN010000000
VERSION     DAFKHN010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.180"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(117..707)
                     /locus_tag="LY912_002916"
     CDS             complement(117..707)
                     /locus_tag="LY912_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBM6956519.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
     gene            1230..1391
                     /locus_tag="LY912_002917"
     CDS             1230..1391
                     /locus_tag="LY912_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBM6956520.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLA"
     gene            1410..1904
                     /locus_tag="LY912_002918"
     CDS             1410..1904
                     /locus_tag="LY912_002918"
                     /inference="COORDINATES: protein motif:HMM:NF018154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBM6956521.1"
                     /translation="MIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGYSF
                     ILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEMFI
                     NAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPIQYTSKELEE
                     ELHD"
     gene            1897..2058
                     /locus_tag="LY912_002919"
     CDS             1897..2058
                     /locus_tag="LY912_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956522.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
BASE COUNT          842 a          360 c          393 g          761 t
ORIGIN      
        1 atgaatataa atagagtgta tcttctttga taaatgtcag aaaaagtgtg acaaataacc
       61 atcagtaaaa ttacttgtca tactattgat aaggagtatt taattgaaga gaatgattag
      121 gagaaaggat ctccgtactt tttatagtaa tcatagaatc caagtttgta tagacgaatc
      181 tttttttctc ttatttcttc tgtttcaaaa tggactgctt gaagaatcaa gtctgtgaat
      241 tctataggag ctgttccatt cgcagtaatc aaattacgat ctttcacagc ttgttgttct
      301 ataaaatctt ctttattctg ataattttcc gattctaacc aaggaaattg cgcatttccg
      361 gtgtgtttgt aaccttgcaa taatccgctc tgagctaaat aatcaactgc cccacaaata
      421 gcagctactg gtacgtctgt ttttaacaat ttatcgatta tttgatataa atgatgattt
      481 tttatgtccc atgaattgcc accgatcata ataaaaaggt caactttttc aggtatttgt
      541 tcgattaagt aatcgatttt tgtttttaat cctccaatgg aagtgacctc tgattggata
      601 gaagcagttt tgttttgcca tccctctttt tggtttagtg tgctagtaat ataagcacct
      661 tcccaatcgg catattcctc taatagaaac gtaatcgcag ttttcatttt caagctctcc
      721 tttactatct atgacaagga caacagtttt aacatacaga cattcattaa atttggatag
      781 cgacagcgaa aacaacaatt cttaagtttt agacagagta tacagacagt caacttaatt
      841 aaatacgaac taaataaaaa tgacaggtaa tcatttttgt ttaccagcat tataacattt
      901 tgcatacatg gatgacaaaa gaaccaattc ccacttgctt gagtacaatc ttaaaagaaa
      961 ctggaaggca aaaagtaatt atagaaacga aaaataaatc atatcgggca ctcagacatg
     1021 aaaacaaccc tagaaatata taactagtcc aatgaaaaaa aagcgaatgc cgtagaaaac
     1081 aaggattctg cgtacattca tatctcattt tgcgagcata tctgctatta ctgtgactaa
     1141 atgttaatat ggttaaaatg accgttatat tttttatata aatatcgtat aattagtatg
     1201 aatatagaag aaggaaagaa ggtgcaatct tggaacctaa agacaagtat ttagattacg
     1261 ctagggtcaa taaagataaa tttattgaaa caatcatcaa gggaaaaatc cctgatgatg
     1321 aaaaagatgc ggtattcatg gctggaagcc caggagcagg taaaacagag gttgcactag
     1381 gtttagctta aaattatgac aaccatgttg tgattgatgc ggactatttt agagcacaat
     1441 ttccagaata caatggaaag aactcaagtg tttttcagaa agcttcttct tggttagttg
     1501 aacaatcatt aaaatatgta ctggaacatg gctattcttt catactagag gatacttttg
     1561 ctatccttag tgcagagaaa aatattattc gagcccttaa aaataacttt cgcgttacga
     1621 ttttctatgt ttaccaagat cccaaagttg cctgggattt cactcgaaaa cgtgaactag
     1681 ctgaaggacg tcatgtgcca aaagaaatgt ttatcaatgc gttttttaag tccagagaga
     1741 atattgaaaa agtcaaaaat agacatcctg aagtagtcct tcacataatg attaaggatt
     1801 atcaaaacga catttctgaa gtgcattatg cagcagataa tattcaatta gtactaccaa
     1861 tacaatatac ttcaaaagag ttggaggagg aattacatga ctgagaaaga acaagtacaa
     1921 caaatcgtga agaagtataa taaaagtatc gctgatttat cagaaaacgc ctcagcgaaa
     1981 gaatttaaaa cagtaatgaa ttacgtagca gatgaagcaa atcggaagca gcgaaaacta
     2041 gttgggttgg ataaataaat tttttaaacc atatccttgt aaagttgagt tttttatttt
     2101 aatgaattaa gactattaaa tagataatta ttgtaactta aaaaacacag ctaaaaatta
     2161 gttgtgtttt ttattaggtt tacttttctg gtataaaagg aactagctac tttttcaaaa
     2221 tttctaaatc attcaatatg tagcgcttac taaattattc gccataaaat tttataattg
     2281 gatcactcat tgttttacct aagtcatatt taagtaataa ccggtgtttt tacataagaa
     2341 gactttgggt attttt
//
LOCUS       DAFKHN010000174         2350 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFKHN010000174 DAFKHN010000000
VERSION     DAFKHN010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.181"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..543
                     /locus_tag="LY912_002920"
     CDS             <1..543
                     /locus_tag="LY912_002920"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBM6956523.1"
                     /translation="ISKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLH
                     TKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNK
                     IRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIH
                     SSIHYLTPQEFEELAKEKMA"
     gene            complement(1016..1588)
                     /locus_tag="LY912_002921"
     CDS             complement(1016..1588)
                     /locus_tag="LY912_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956524.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENCVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1604..2209)
                     /locus_tag="LY912_002922"
     CDS             complement(1604..2209)
                     /locus_tag="LY912_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBM6956525.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          741 a          467 c          359 g          783 t
ORIGIN      
        1 atttcaaaag agaatctctt aaatcaggac ttttctactg aaacgatctg tgagaaatgg
       61 gcagctgaca ttacgtacat tcctactaag aaaaatggtt ggtgttactt atcttcaatc
      121 atggatttac acacgaaaag aattattagt tatacatttt caaaacgaat gactgtggat
      181 tgtgtcattc aaacattgaa taaagcaaaa atacattatc acattccaga aggaatgatt
      241 ctacacactg acttgggcag ccaatacaca gcaagagaag tggaacaatg gcttaaaacc
      301 aacaaaataa ggcattctta tagtagaaaa ggaacacctt atgataatgc tggaatcgaa
      361 tctttccatg cctcattgaa aaaagaagaa gtctacacga ctagctactc agattttgaa
      421 gaagcaaatc gagcgctatt tagctacatt gaaggatttt ataaccgaaa tcgaatccat
      481 agctcgattc actatctaac cccacaggaa tttgaagaat tagcaaaaga aaaaatggct
      541 taaccgtctc tactaaaatg tgtccaagat attgactcaa atccagtaat atcacaatag
      601 gaatgctgtt tattatatta gcagcagtgc tgatttttat gatagttatt tggttcttaa
      661 atgaaagatc taaagacaat caacaccgta gggatatgga gataaaatca atagagtcaa
      721 tagattattt atcgataata acactaaaaa agccacgttc ctaaacgtga cttacgctga
      781 acgatatgtg ttgtttggta gacgaacaaa tcgttcatta taaatatatg atggtatcct
      841 aatatagtaa gcgtggctag cataccttta attactttac cttttacagt taccatacac
      901 attttttgag cagaaatcaa gtaaataaaa aaatattata tttcacaaca tgctaataga
      961 ctcatatcta gaacgcatta agtatttacc tgtctggttc gctgagactt cttttttaac
     1021 tttcttcaat tttcttcttt attctaaaaa gcgtactgcg actgaaaccg gttatagctt
     1081 caacttcctt atacgattta cctgaagtaa gcagttcata tgcgtgcctc ttcttcggtg
     1141 tgattgttgc tttcggacgt ccttctctga aattaggatt attctttctt gcaaacattt
     1201 ttccttcttg ggtacgttcc acaatcatat cacgttccat ttctgctaca ctcaacaacg
     1261 tccgtgtcac cattcgcccc atggacgtat tttcaatcgt tcctagattc aaaaccttga
     1321 tcgttacgtt atcatcgagt aaaggttcaa tgatctctaa tgcttctctc gtgttacgag
     1381 caaatcgatc aagcttcgta acaactattt catctccagg cttcagacca gccaacagct
     1441 gattgaattt tggccgatcc cgttttgtac ccgtaaattt ttctgaaaaa atattcttct
     1501 tctctacgca gttctcaagc aactgttgaa tttgttcttt tgtactttga gaagcggttg
     1561 agacacgtgc atatccatat ttcgtcattt ggtccaccta cttttacaaa tcatctatcg
     1621 tatactcaga atacccttca tagaaatagc tgacatcgat tcctttcata tataactcgc
     1681 gatcgtcaat tttatcagtc agagcattgg aaattagata gcgtatttcc aaatcgttta
     1741 tgggacttcg ctccattgca gaaagatagt ctgctttatc gattaagttc caatctacaa
     1801 ctttttgcaa ttcttccttt aaaatgagat ccagccaaat tctagtactt cggccatttc
     1861 cttctcgaaa tgggtgagcg atattcatct ccacatattt cttgataatc tcttcaaaag
     1921 aagtttgtgg catctgatca atatgctgta acgaatgttc taaatacata actggtgcaa
     1981 atcgaaaatt tccttttgca atattgaccg atcggatttt tccggcaaaa tcgtaaatat
     2041 ccgaaaatag aaattcatga atttcagata aacctttaaa tgtaccaact tcgatttcat
     2101 ttatttttcc acaatcgtac aattctttcg ctttttgttt actgagtttt tcttcaacct
     2161 tagccaactc aacttgattg gttaatccca atttattctc taaaatcatg cgaaatctcc
     2221 ttaactttat gacataagtt tatgaaacac tctcaacccc attatatcgc gattttgttt
     2281 atgtgtcaaa aactattaag tttctgaccc ccgatagatt tttcaagtgt ctctattttg
     2341 cacagtctag
//
LOCUS       DAFKHN010000175         2335 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFKHN010000175 DAFKHN010000000
VERSION     DAFKHN010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.182"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(51..1598)
                     /locus_tag="LY912_002923"
     CDS             complement(51..1598)
                     /locus_tag="LY912_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBM6956526.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="LY912_002924"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="LY912_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBM6956527.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="LY912_002925"
     CDS             complement(2043..2237)
                     /locus_tag="LY912_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956528.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          653 a          483 c          420 g          779 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga agacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agtaaggtac tgttctatgg ggcgcttacg ttaaaaatgt tttgc
//
LOCUS       DAFKHN010000176         2272 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFKHN010000176 DAFKHN010000000
VERSION     DAFKHN010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.183"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            212..394
                     /locus_tag="LY912_002926"
     CDS             212..394
                     /locus_tag="LY912_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBM6956529.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            497..781
                     /locus_tag="LY912_002927"
     CDS             497..781
                     /locus_tag="LY912_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956530.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            797..1033
                     /locus_tag="LY912_002928"
     CDS             797..1033
                     /locus_tag="LY912_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956531.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            1055..1309
                     /locus_tag="LY912_002929"
     CDS             1055..1309
                     /locus_tag="LY912_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956532.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            1391..1576
                     /locus_tag="LY912_002930"
     CDS             1391..1576
                     /locus_tag="LY912_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBM6956533.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            1643..2038
                     /locus_tag="LY912_002931"
     CDS             1643..2038
                     /locus_tag="LY912_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBM6956534.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
BASE COUNT          792 a          388 c          404 g          688 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acccgtttat gtttatgtat atgtatatga
       61 atataaacgt attaggtacg aacactttta aattcttttc tgggctttgt ttttagggta
      121 gggctaaaaa aaacatcacc atctgatcca aaacagctca gaaacgcatt taaacgtatc
      181 tgataccaat attacagaag gagtgtatcg tatgattaac ctatttcttt tagtgacagc
      241 tagtacatta ttctttactg gaatatcact gataatttcc tatttgatct ataagaaagc
      301 cgaaaatcac acaagcaaag caatcggact agccgtttca tcctttttaa ctttgctgac
      361 tttatttgtt actttatcgt tttcttttgt ttagaacagc tgatccatta gcaccttttt
      421 ctctttacat tatacacact gttgtgtata atgtatttgt aaacaagcta attaactttt
      481 aggaaggagt gacaagatgc taacagctac tttacagcaa cctactcacg ttgctattgc
      541 agaaagttat acaattaatg cagggatcgt taaacagctg atcaaggatc gagaattcaa
      601 aaagtttaac agtcggcaag cgtataacag acagctaaag aaagctattc taaagcacaa
      661 agattccttc atcgggaact tggaaagtgt agatgttaaa actgtttcaa cggcattttc
      721 agttgttgaa gtgactattg acggtcgctt gatttctcta tttgcttttg gaattaattg
      781 atagggagtg tgaactttgg aaggtaagac ttttgcagaa atttggactg aatttattga
      841 ggtaccaact cgcattgatc cgataacttc tgaaaaggta ttggatgcag acttctacaa
      901 tctcaaagca ggtactagcc ttgaatgcgt ttggatgtat ttagaagagc atttcaaagg
      961 cgtaacgctc ggtcacgtct tataccacaa tggtgccgag tgggatgcaa ttggaaatat
     1021 ccatttttct taatataaga aaggagaaca caatatgaat tataccgatg aagaacaaat
     1081 cgctttggaa tacgttttca caaatgaaga aggggaggaa attgaaaaag tcttgatcat
     1141 ttcatcaaaa gacttggaga aggctttggc ttatgaacca tacgaatcaa ccgtaactgt
     1201 cattgaattc ttagatacct atacttctaa tgatacttgg gaaattatga atatttgcaa
     1261 cgctaataac attcaatttg ctgaaaaaac caataaatca ttttattagt tttgcaataa
     1321 aacatcctct ttttctattg attccataca caacaatgtg tataatagat tttgtaaagg
     1381 gagggtagct atgcctaaga cagcaagaga aattgtaaaa attctcaaat ctaacggctt
     1441 caaaaagact ggacaaactg gcagtcatgc aaaattttat aattccaaga ctaaaagaac
     1501 ggtcgttgtt ccgatccaca atggtgatgt accactagga acagaagcta atatctggaa
     1561 gcaagcaggg ctttaacagc cttgccttcc tatttggtat taggcatact atcctctctt
     1621 acactagaaa aggagcgagg aaatgaagac aaaaaatatt ttttatccgg caatcttcga
     1681 gaaagaagga gaagcttata acatcgtttt ccctgactta ccggaaatat ctacctttgg
     1741 aaatagtctt gaagaagcat atttaaacgc taaggatgct ttaggattag cgctatatag
     1801 tgtaccagat gcagaatttc ctaaaccatc agcagtggaa gaattaactt tgaaagccaa
     1861 ccaagtggta gtaatcatcc aactaaacat taaacttttc cgaagaagct taaatacaaa
     1921 aacaattaga aaaaatgtta gtgttccgga atggttagtt cttttaggga aggagaaaaa
     1981 cataaacttc tctcaactac ttcaaaaagc actagaagaa gagttgcttg aaaagtaaaa
     2041 aggagaccga acctatgaaa gctacacact taaactattt ctctcgaacg ttaatcaata
     2101 atctattaaa agatacaact ggcattagcg ttagtaccaa acactttgcc aatgatctaa
     2161 ttatttttga ggataataac ttgcgaattg agatgtttat tgaacaggca acccctaact
     2221 caatacctga attctgctat acgcacactg aaaaaatgaa acatgcaaaa tc
//
LOCUS       DAFKHN010000177         2263 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFKHN010000177 DAFKHN010000000
VERSION     DAFKHN010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.184"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(148..2145)
                     /locus_tag="LY912_002932"
     CDS             complement(148..2145)
                     /locus_tag="LY912_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBM6956535.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          576 a          507 c          411 g          769 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caa
//
LOCUS       DAFKHN010000178         2115 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFKHN010000178 DAFKHN010000000
VERSION     DAFKHN010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.185"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..423)
                     /locus_tag="LY912_002933"
     CDS             complement(<1..423)
                     /locus_tag="LY912_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956536.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYT"
     gene            complement(554..1276)
                     /locus_tag="LY912_002934"
     CDS             complement(554..1276)
                     /locus_tag="LY912_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956537.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            complement(1282..1527)
                     /locus_tag="LY912_002935"
     CDS             complement(1282..1527)
                     /locus_tag="LY912_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956538.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            complement(1538..>2115)
                     /locus_tag="LY912_002936"
     CDS             complement(1538..>2115)
                     /locus_tag="LY912_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956539.1"
                     /translation="KQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGYMIL
                     DWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMTTDT
                     GYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANIKTA
                     FGDIETSIKELREYVQNPYNFQYLAGRINLV"
BASE COUNT          624 a          381 c          285 g          825 t
ORIGIN      
        1 tgtgtagtta tacatgggct ttcctgatgt cttgtagtca tttaagcttg gatatatttc
       61 agttttccat ttttcttctg aacgttgatc aataattctt aatttttcag gtaaatcaat
      121 ttcatagtat tcttcaattt tcagctcacg ataaagtaga tgtttttcct tttctttttc
      181 aattacaaaa gaattatttc ccttcagttt agctatttct tcacttgtga gaccaagcct
      241 aattttttct acttcacttc taagttcacg aatacttgtt gcctttaacc acttcccatt
      301 tgcaccatta ttgtaaccgg taagtaactg tattttataa attccttcac catgaagcac
      361 cttatatata ccaacctgat tcttttgcgg aatatgagct tcatttgcac tgatttcttt
      421 cattacgcat tctcctttat aatctagtta attagcttgt gtgtttcgag tagttgagta
      481 agaacgtttg tttcagaaat catttatttg ttatcactta attttaaaaa aatagggctt
      541 acgccctaaa gatctattta actttggatt gatcgtccat aacaggctct gattgttgat
      601 ataatttata tgctcccaaa tccatataat atttagttgt actttcaatc atttcatcag
      661 ttgtatttgt tgtcattccc attacatccc agtatagtgt gccgttaact ttctttggtg
      721 ttactactgc aactgttggc gtatgatatt gattgttctc atcagccaga ccaggaatgt
      781 tttgtaccca ctcaggtaca ccatcagtaa tatctacagc aactgcgtaa tactcgtaag
      841 ctggtttatt tatggtaata tcatgcatta atgttggagc ataactaaat ccttctttta
      901 tttcttgcat gatttttgat tctgcttttt gacaatctgg acaatcaggt ttgtaaagaa
      961 cgatagtcag atttttattt tgcaatggat cattcccata attttcatca ttttttactg
     1021 tattaataaa gttgttataa acttcatccg gcttttgacc tttattaatg tcttcgtatt
     1081 tttgatactt ttcagcatta ttttcagtca ttgaagacat tgttgttgat gccgatgtag
     1141 tgctgttttt agtaaccatc gtactactag actttgtgtc tttgttatta ttagcactat
     1201 tagttgtacc acatgctgta agggttatta atgctgctgt cgataacaat acaaccttca
     1261 atttagttga tttcatttta ttcacctatc cttttttctt ttgtttaaca ataaaagaat
     1321 aacccgtact atccaataaa acaacagcat caatatggaa acccaaacca tttgtacaat
     1381 ccaagcataa agactaaata ataggtattg tggatttttt tgaatgattg tatttgagat
     1441 gccatttcct acagtaaaat acattgttac gaaaataaca ccttcaatta tcaagtgatt
     1501 tgttggttga tttataattt ttttcatatt tttactccta aactaaattt attcttcctg
     1561 ctaaatattg aaaattatat gggttctgca catattccct aagttcctta atacttgttt
     1621 caatatcacc aaaggctgtt ttaatgtttg ctgacccatc tttatataca atcatttccc
     1681 cttcacccat acaaaaagaa atttcagtat tagaattgat tgttttttca gcacgaccat
     1741 tgataatttc ttgaccatca cgccatataa aatacataag ataaaatacc tcataagcgt
     1801 tgtatccagt atccgttgtc attgatacca aaacatcagc atcttgtatt cctgataaag
     1861 ctaatccaat ttcatggatc acatcaactt cattttcttc ccaatctcca ctttcgaaga
     1921 cggtataggt ttgattgtta gcaaatggtt ttctttctat atcgaacatt cctttccaat
     1981 caagaatcat gtacccgatt aaattgtgaa agaaaattag ataaaataaa tacaataaga
     2041 tgctaactac aaaaatatca gccattattg acataggatt atcaggatat aaccagatgt
     2101 aaaacgattg tttca
//
LOCUS       DAFKHN010000179         2113 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFKHN010000179 DAFKHN010000000
VERSION     DAFKHN010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.186"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            23..508
                     /locus_tag="LY912_002937"
     CDS             23..508
                     /locus_tag="LY912_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956540.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            964..1377
                     /locus_tag="LY912_002938"
     CDS             964..1377
                     /locus_tag="LY912_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBM6956541.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            1892..>2113
                     /locus_tag="LY912_002939"
     CDS             1892..>2113
                     /locus_tag="LY912_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956542.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFS"
BASE COUNT          663 a          336 c          351 g          763 t
ORIGIN      
        1 atctatttta ggaggagcta tcatgcataa agggatttac gcaggcttgt tgggaactgt
       61 aatacttttt tctgcctgtg gatataaaac aaagaattct gttaaagaat cttcagcagc
      121 catttcaaca actgaggttg gttcaactaa aagtacttct actacttcca ttactaatac
      181 ttctactggt aatgtagatt cgcaacatag ccaatcaagt attcagtcgt ttagcatttc
      241 ttcaacatct gaaatgcaag aaagcactgt accttctctt ccattagaaa actctgacaa
      301 agcacttcta tttcttattg cccaccgttc cgaattacaa agtgacgata ttgttattag
      361 cttttatcaa aaaattgatc gagattattt gttcacagct tccagcaaac aaatccgttc
      421 ccaaggagga tctggaagcg ttggttttta tcgagtgtca cccgaaggat cgattacgat
      481 gacagatgca aatggaacac cattttgatt agatgatatt atacggattt acagtactag
      541 caagtcatta ttggtatcat tttttctgag aaagttatac ggagtataaa taagcatttg
      601 cattaaccta ataattcgtt acagctattt ctcttatgaa tatactcact tctctacttg
      661 ctctcttgat aaatttttgg tatctacttc attttcggtc aactgagtta atgaaattta
      721 ttgtcgggcg gttttctaga ttcaattttt ctatatttgg atagaagaat ttactttttt
      781 accttttgac atattttctt cttattattt taatgatccc tttttcaaat tagaaagata
      841 gcctttgtat cgtattagat gaaatattca caaagctaac cattatactt gcattttttt
      901 caaaatagag ttattacgta aatagggata aataaaaaat acttattgaa aggatgatca
      961 aaaatggcaa atgtacctag cattcgcgac atgttccctg atttcaatga cgtgtttagt
     1021 ccagcattca atgatttttt aggtgtttca agttatccaa aagtagattt agtcgaaaat
     1081 gaaaaagaat acaaactaac tgctgatatg cctggctgtg acaaagaaga cacgacagtt
     1141 gaatattcag ataatacttt gacgatctcc gccaatcatg agtcccatac agaagataaa
     1201 gaagatggca actatgtacg gaaagaaaga cattcggtct cttacaaacg ttcattctat
     1261 cttcctaatg ttgatgaaga aaaaatcact ggaaccttta aaaacggtgt gctgaaattg
     1321 gtattaccta aaacagctta tcagccaaaa gaaacaaaaa aaattgagtt aaattagaac
     1381 ttatcgcctc tcgatgaatg aggggcgatt tttatatatt tggataagaa cgagtatgtt
     1441 taaattttca aaatgagcaa aaaaatattt tgtttttacg ataaagatgt tatgatctct
     1501 cttggtaaaa aatatgggag ttgatcattt gattgtctta agtaaacttt tgttttggat
     1561 accatttatc ataatgacca gtgctttctt ttacttattc aaaaggccta acaaatactt
     1621 actcttatct gcttgtccga tgatctattt tatccataag attagaggat tttattatta
     1681 cgactctggt atctcattgt tttgctacga aatcggctta ttagcttcgg ccatcttttt
     1741 catatttgtg ttagaatatt tcagaaaaaa ataaacttcc agtcagtttt ggctggaagt
     1801 tttttatttg gtgcagatct tttcagctgt tattcataca agttgatcca tttttctatt
     1861 attaagtaca taccattgtt actctttgaa tgtgggggag aaaaaaataa aaggagctgg
     1921 tattttgtta gttatgagta aagctttgtt tttacttccc tgcacgttca tgtttattgt
     1981 tttatgttat ttcaaaagaa gaaaaaaatg gtgctggatc gatgttctac tattccttcc
     2041 ctttttcccg cttatttatt ttcttgaaga aatatgggat gatatggcat gtgattctgc
     2101 ttttcttttt agt
//
LOCUS       DAFKHN010000180         2067 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFKHN010000180 DAFKHN010000000
VERSION     DAFKHN010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.187"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(589..954)
                     /locus_tag="LY912_002940"
     CDS             complement(589..954)
                     /locus_tag="LY912_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956543.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1030..1275)
                     /locus_tag="LY912_002941"
     CDS             complement(1030..1275)
                     /locus_tag="LY912_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956544.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1345..1599)
                     /locus_tag="LY912_002942"
     CDS             complement(1345..1599)
                     /locus_tag="LY912_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956545.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1763..1975)
                     /locus_tag="LY912_002943"
     CDS             complement(1763..1975)
                     /locus_tag="LY912_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956546.1"
                     /translation="MIFQGVITLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIIL
                     SFLVNAIVLFLYVLNYLDINPLIFSR"
BASE COUNT          762 a          353 c          368 g          584 t
ORIGIN      
        1 ttttttaaag aatatttaga aattattaat tttcgtctga aaacaaaaaa agaaagcgtt
       61 attattttag tctattttca gggggggaac cttatgataa aaaaactatt tttactatca
      121 atattaacgc tagcaatggc aggttgttct gactctggct tagcaactga actgatcaca
      181 aaatcaactg aagccacgac agaggagtta aaatgtggaa acgatcacag tgactacaga
      241 ggcttaaatc gacgatgcat gggaatatta ggcagaagca attgtaagca tcgatgtagt
      301 aatcgaagaa ggtgtagaag aagcaacaga aaaatcaaaa gaaagatcaa aagaagcaat
      361 ctgtgctgtg catcgtatac agacgtcgaa gatgcggtac ttttaaacca cgtcaggaga
      421 tgttcattta tgtctaggga agttggcgat gaaccaaaac tagagtacgc ttttagtttt
      481 gcacgtgagg atgaagataa ccctaaaact tacgacattt tagcttgatc taagatggtt
      541 aaagcttttt aatgaagtaa gaggagatag aaggcttttc tagttatatt aggtaagata
      601 aattcctttt tgctccaaat ttgctaaaca ttctgctaga taaacttcat cgtgttccgg
      661 ataaatcggc acgttgcgct ctacagtagg taaatcaaaa aatgcttcgc atgatttgcc
      721 acgatacata ggatttttcc actctggtgc tgggctgtaa ccacgttttt ccatttcatc
      781 catgacaagc tgatgatatt ggaataatct ataaggagaa tagtgaaaaa cataatccac
      841 agtagcatgt ttctttcccc agccatttcc tcttaatgca cagcattccc gatgttgtcc
      901 taaaagctgt tgacgaggaa gctttgaaat caatttttca tgccataatc gcatagaaat
      961 gtctccttta tatatagatt gttaacctta gacgttaaat gaaaaaacca gcaccaaggc
     1021 tggaaaaaat cacttcagtt tgcttgctgt ttctgagcga ccaattaggt aatcaacgga
     1081 aatatcgtaa aagtcagcga tatagattaa ttcaatgatg cttggaattt cttctccttc
     1141 ttcgtactta cgatatttga ataaaggaat acttaacgcg ctagaaacag ctacttgaga
     1201 taaagatcgg ccagttctta agaaattcag acgacaacgt aaagtatcca gtaaaatagc
     1261 ttcttcgata ctcatttaat cacctttcat tatagtagaa tagttataat gactatagaa
     1321 agctacacat gcaatcaata gtactcaatg ttttttattt aaacgtatca aataaagaat
     1381 gacgatcaat aaagacaaaa ccagtcctga taattcttct ataaaaacac tatcgggttc
     1441 aaagtagttg taattaaaaa ctttccacat aaagtagata gccggaagag tcaaaatagc
     1501 taaataaaac cgttctttgt tccaattcat aagataaaca atacttgcga ccagtgcgac
     1561 cgcaggcacc caaaacaaaa ctctcaccaa cgtaatcatg taacggactc ctcaacgatt
     1621 catataataa aagataacat gttattgcat acatcacaaa tgaaatgcta ggaaaataaa
     1681 agaagaatag atcaatgaaa aatgaaaaag cagaacagtt ttctgctgat aagcaggaac
     1741 tgttccgctg aatgtgtctt atctatcgag aaaaaatcaa tggattgata tctaagtaat
     1801 tcaatacata taaaaagagg acgatcgcat tcactaaaaa ggaaagaatg atgatcccat
     1861 agcgaatgga aacatattta acaaatactt ttgtttgaat acgggcatat ctttttcctt
     1921 tatagctgag catcatgaca agaagcaaaa gggtaatcac accttgaaaa atcattccaa
     1981 taaacagaat tcctgaggtt tgataattta attggagaaa ataagctgct gccgcaacta
     2041 aatcgaataa aatcgcaata aatggca
//
LOCUS       DAFKHN010000181         2001 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFKHN010000181 DAFKHN010000000
VERSION     DAFKHN010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.189"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..377
                     /locus_tag="LY912_002944"
     CDS             <1..377
                     /locus_tag="LY912_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBM6956547.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            425..1825
                     /gene="yfcC"
                     /locus_tag="LY912_002945"
     CDS             425..1825
                     /gene="yfcC"
                     /locus_tag="LY912_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBM6956548.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1858..>2001
                     /locus_tag="LY912_002946"
     CDS             1858..>2001
                     /locus_tag="LY912_002946"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956549.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          553 a          339 c          432 g          677 t
ORIGIN      
        1 aaaatgtttc cacagaggac ttctttaatt attgtcgatt agaggaaagt ggtgtaacag
       61 tcactagcgg tacagattta ccgctgttta ttactgatat tcctgaatcg attataagag
      121 cagtattccg tcgttttcct gaaggagaag aagtctggga gaaagaaaca agcttcacga
      181 caaccgagct gctgaaaagt tttacaagca acagcttcaa agtaaatggt ttatcggagt
      241 acggagaaat aaaagtaggg aaaagcgcca gcttagctgt tttcagcgag gacctctgta
      301 ctgatgactg gcaaaaagtg atggctgcgg aagttatcgc tacctatctt gatggtgact
      361 tagtttacaa gaaataatgc ttttcgatat aacgttataa aacgaattaa agagaggtta
      421 aaaaatggaa acaatgaaaa gaaaattcac cttcccacat agttatacat tgatttttat
      481 cttaattatt ttggctgcaa ttttaacttg gataattcct agtggtcagt ttgagacagt
      541 tgttgaaaac gtcgcaggta tggaaaaaac aacggttgtt ccgggaacct atcaccaaat
      601 cgataaggca gattatggac aaggtttttc ctctatacta atggcaccag ctgaagggat
      661 tatttcagct gttgaggttg ttgcttttgt tctcatcgtt ggtggtgcct tcgggattat
      721 cctaaaaacg ggagccatcg atcgagggct gtttacctta gcaaaagttc tgggagacaa
      781 ggggatctta gttattccga tgtcgatgat tctattcagc ttaggaggat caacctttgg
      841 catgagcgag gaagtcattc ccttatttgc ggtgtttatt tctctgatgt tttctcttgg
      901 ctatgattcc atgactgcga tcttgattct atttttaagt acacaagcgg gatatgttgg
      961 gtcgacgatt aatcccttca acgttttaat cgcacaggga gtagctggcg tttacggaaa
     1021 tcccctgctt tggtttcgga tgctatcctg gattgtcatt actgggattt caattgtttt
     1081 caccatgctt tatgctagca gagtcaaaaa gaatccactg tcctctattg tttatgagag
     1141 tgatttaaag gttaagcata agtttcaaaa ttttgacact gaaaaagagt tttcaacaca
     1201 agataaacta attatcgccg gttttatcgt aggtttagga atcatgattt ggggtatcat
     1261 ttccaaggga tggtatatgg ttgaaatttc tgcactattc ttaggattag gtctttttgc
     1321 tgggggcatc gctagatttt ctcaaaagga aattgctgaa gcttttgtcg aaggctgttc
     1381 agatttcgcc tatgctgctg taatcattgg gctagctaga ggagtcttgg taatcttgga
     1441 aggtggaatg attattgaca ctattctaaa cagcttggct aaccttttag gtggtcttcc
     1501 aaaattcctg ttcactacga ttctactcat ttctcaagta attgtttcct tttttgttcc
     1561 atcctcctca ggagctgcgg cattaacgat gccggttatg gcaccattgg gtgatctaat
     1621 gaatgtaagt cgtgatgttg ttgttctaag taaccagttt ggaaatggtt taatgaatat
     1681 tatctcccca actagtggtg tattactggc aggattagcc atcgcagaga ttaatttctc
     1741 taaatggttt aaggttggct tcaaaatatt tgccatctta acccttgttt ctgctgtttt
     1801 gttatacatt gctacactct tttagtctta atcatccatt aataggaggc aatagttatg
     1861 attaaaataa atcaattagc aggaatgaat atccactatt tattttattc tctcaaagaa
     1921 tttttcgctt atcaacagaa aattggtatt tcttctgttg aactttgggg aggtgctccg
     1981 cattttttca tagatgcttt t
//
LOCUS       DAFKHN010000182         1985 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFKHN010000182 DAFKHN010000000
VERSION     DAFKHN010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.190"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..741)
                     /locus_tag="LY912_002947"
     CDS             complement(<1..741)
                     /locus_tag="LY912_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBM6956550.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGICYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEA"
     gene            complement(745..1803)
                     /locus_tag="LY912_002948"
     CDS             complement(745..1803)
                     /locus_tag="LY912_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBM6956551.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT          635 a          424 c          327 g          599 t
ORIGIN      
        1 agcttcatta tcttgaagct ctccacgggc tgtattgatc aagatgctgc cttttttcat
       61 ttgagctaaa aatccttcat tgatcatttg atcgttttca cctgggatat gaggtacatg
      121 aatactgacg atatcgcttt tggctaataa ctcttcaagc gagtggaacg tcaatacttt
      181 tttagcagct tctgtctgat gaatatcgta gccgataact ttggctccta gtcccttaaa
      241 caaaacagct tccgtcaacc ctatcctgcc tgttcctatg atccctactg tgcaatttct
      301 gatttcacga ctaaacattt gctcatccac tcgaaaatct ttgaaagatg ttcggatcgt
      361 cgtatacgca gtatttctca aaagcatcat ggcaaaagtc aaagataact ctgctatcgc
      421 atttggcgaa tacgatggta cacgggctac tgtcatacca aaatcagctg ccgcttgtag
      481 atcgatatga ttgactccca cagtccgtgt aaaaacataa caaatcccat attcctgcat
      541 ttttgcaaga ttggtctcat ctgctataca atttcccctc aacaatacag catcatggtc
      601 ctttgctgac acgatattgt catgtgtcaa cagttcttca taaagactga gatcataatg
      661 gtaaatattc aatttttcaa aaaaatctat ctcgttcgga cgaacaccgt aacatgcgat
      721 tctcatactt tcttcctcca tttcttatga aaataaacct atgccatgaa tcatttgtaa
      781 tacaacgatc catacaggtg tcagtaccac agcaaaaata gttgacagta aggatgcatt
      841 ggaggctaaa agtgcctccc tatcaaaact gatagcatag gctgctgcca ctgttgcagc
      901 tggtgtagcc atcatgataa cgattgttgc cagtgcttca aaattgactg gtagaatatt
      961 cgttgccgtc aaaactgcta gaatcacgat attcaatgca ggtacaaata ccactttgac
     1021 tagactgtaa taccatgaag ttttttcaga tgcagctttt ttgaagctta cttcacctaa
     1081 tgttgcgccg attgctagcc acgccaatgg tgaacttaaa ccagctaaat aatccatcgg
     1141 ctgaaatagc cacggtgcag tctggtcaat tcgcaaaaac gctacttggc ttatctctcc
     1201 ttctgcacct gtaactgaca cttgtggcag atacccttgg aacagccaaa tgaaaaggcc
     1261 ggcaaaagta gcgataatga ttggattgac gaacatcgct ttgatatttt tagcttccat
     1321 cttcaagcca ctcattttta tgtatccata agaatacaaa aagattcggt agccaatatt
     1381 gaaaattgag gaatacatca cgccgacagg accataaatc gcactgacga taggcgttcc
     1441 gaaaaaggtc gtagaaccaa agatcgtcag gacacgcaac gttgtttgct tatccccttt
     1501 atagcttaag aaaaaaggtt ttgaaactag aataagaata atataaataa ctaatcccca
     1561 aatcaagaca ttgattcctt gcatcagtaa ttctgtattg atatcttgca tgaaagctcg
     1621 aaatgccagt gctggcaaag ccactgttaa gacgactttc gatagaattt ttccaacaga
     1681 ttcagaaaaa atcccctttt ttctacaaac aaaccctaat aatataataa aaactgttga
     1741 agtgattgca ctgacaatcg acatatctgt caaagtcgat cgaaaaatgt caaataagtt
     1801 catctttctc ctcctaatta tgttcattta ttcacaataa aaaaacgctt ttattttgct
     1861 aatacgtatt aacattttta attttatctt tacattgtta cttattgaac aataggaaat
     1921 taaagaaact tttgaaactt atgtaaagtg atttttacta gaacacaaaa aaaaccttaa
     1981 aacca
//
LOCUS       DAFKHN010000183         1967 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFKHN010000183 DAFKHN010000000
VERSION     DAFKHN010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.191"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(180..632)
                     /locus_tag="LY912_002949"
     CDS             complement(180..632)
                     /locus_tag="LY912_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956552.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(639..1187)
                     /locus_tag="LY912_002950"
     CDS             complement(639..1187)
                     /locus_tag="LY912_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBM6956553.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(1232..1564)
                     /locus_tag="LY912_002951"
     CDS             complement(1232..1564)
                     /locus_tag="LY912_002951"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956554.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(1578..1835)
                     /locus_tag="LY912_002952"
     CDS             complement(1578..1835)
                     /locus_tag="LY912_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956555.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
BASE COUNT          661 a          403 c          201 g          702 t
ORIGIN      
        1 gtgaagtagt tattttgaac tttaactttt aaaaacttta aaaataatct tatttgttct
       61 tctaaacaat catctatact catataatca ctccactaat taatctcccc aaaaagacac
      121 agcattaaga gatataccaa cacaacagtg caaataactc tacatcttcc ttcgcaacct
      181 tatttcaata aaccataaaa attatttttt aatagaaact gaaaattaaa actagaaaaa
      241 gtagttttac cgaatgtaag agcatcatca ccatcaatat agaaatacat tcttttccag
      301 ttacatttaa tttttaaaca aaattctccc caaaaaggaa ctttttctag tgaaaacttg
      361 gtaatctctt tgtaattaat tcttgttaaa gaataattaa acacttcatt tttacttgtt
      421 attttttcat tgactataac tagttcatct ggtaaaaaaa ttaaccaaca aacatcgaca
      481 aacagtaaat gatataatcc atttccacct ccaagcatat tcaatactgg tgaacatgcc
      541 ttagaaacac gaatatagtt atggtttaaa tagatatttt ctttaaacat tgcttgttta
      601 aaagccatat gctcttgttc taaacttttc ataaactttt actctaatgc acagctagca
      661 gcagctgctg caattcctgc tacaatattt accttagcta actctttagc tgcagctttt
      721 cctaattgtt tttctgcaat ttttaataat aaatccgcag ctttttcaaa attaaaagct
      781 tttaatgctt caataaaatc tccctgcgta cctatagccc aagccactcc tcctccagga
      841 agagaattaa tggctacaca tccagcatat cgtttccaat caactttctc cattctagga
      901 acaataatat gttcataaaa gactcttgct gctcttcctt gttcgttatc ttgactgatt
      961 cgttcacgaa tagcaccaaa atcctttata tggtatacac catgttcgtc taaaaaacca
     1021 actgtatcaa aataaaaagt taattcatct actaatttat tctttatttc taaatcaact
     1081 gtattcactt tttctgtggc atacacactt gttccagtac taacaaaagt acttaaacct
     1141 aataagaaaa cacctaaaac accaaatatt ttaattattc ttttcataat ttctcctcca
     1201 taaaaaataa gttacttttt aaatatcttg tttatgaatt cattccccaa aggcctttta
     1261 agattgatac agcagtccgt tcacttcttt tagacttgtc atacaagtct tttaaatgat
     1321 cccatatcag actagtttgt ctatctagct tcaatccatt aaacgctaat gaacggttca
     1381 ttttttctat tactttagat aaagctacag aaatttttat accttcacaa cgcgcatctt
     1441 ggatttcaat aatagtatca tcaattagtt tttgaatttc ttgcctatca acatattcaa
     1501 tcttagaaag agaatctttt aaagctacta atgattcaac gatttctttt ttctcttcag
     1561 acattttctt cctccttcta gtgacccgta aagccatgta gagcagagtc cattgaacca
     1621 gtaattacac tatctacaac gccattccaa tttactctac attttccatt tttcagattt
     1681 gtcggtccat acggatagcc tttttgacat tcaatgttcg gattatacca gataggatta
     1741 taccattcag ccgcagaagc agattcagtc gatacaaaca atcccacacc aacaaatcca
     1801 atacacatca cactatagcc aattagtttt ttcatctcgt atccatctcc taaaaaatag
     1861 aatagttctt atagttattc ataagacata ttttttccgt ttttgtttta tcctttctgt
     1921 cctataacaa cttttttcaa gtaaagaatg acatagtttt tcttaaa
//
LOCUS       DAFKHN010000184         1963 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFKHN010000184 DAFKHN010000000
VERSION     DAFKHN010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.192"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..203)
                     /locus_tag="LY912_002953"
     CDS             complement(<1..203)
                     /locus_tag="LY912_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956556.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEES"
     gene            complement(225..1586)
                     /locus_tag="LY912_002954"
     CDS             complement(225..1586)
                     /locus_tag="LY912_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBM6956557.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            complement(1659..1958)
                     /locus_tag="LY912_002955"
     CDS             complement(1659..1958)
                     /locus_tag="LY912_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBM6956558.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
BASE COUNT          640 a          436 c          299 g          588 t
ORIGIN      
        1 attgattctt ctattttccg ttttcttttt tcatcgtact ctctgaataa aacgtgattt
       61 ccatatttat agatcactag tgcgaaaaaa atgaccaata gattgatgat gatattttga
      121 gtaaagagtc catatagaaa tagcagaagt gtaccacaaa gagcgactgt ccattttatt
      181 ttatctgtct cttctctttt cattactttc ccaccatttc aatgctattt ttgtagttca
      241 gcataacgtt cactcggtac tttcgctttt atcatatatt tataaagtag aacaaacagt
      301 cctagaaaaa tcacgcatcc tacaatagcg agaatattcc tattaaatgc ctccgcaaat
      361 aaaaccctga actccggtcc ttctatggat gaccatgtga tcaactgtcc tttcttgatt
      421 ccctcgactg ctccgctttt ttctgctgaa tcactgagta ttggcgcaag gtaagtggcc
      481 ccgtacaaat aaataggcat cgtgaggatt cccaagatca gcatacgagc caagtttcct
      541 cctgttaaaa gtaatccgcc gaccgcaatc gaatagttga taatccctgc taatggtaat
      601 acttggtttc ctggcaaaat aatggcataa ccaataaaca caggaacaag taaaatagca
      661 gtaacccaaa tttctgaacg accagctaat atcggccagt ccaatccgat atatacttca
      721 cgatccttaa accgcttttt cataaattct gacatagcgt ctgctagagg agacaaagat
      781 tgcatgaaca ttttagagat cataggaaac aaacttaatg ctgtagctgt ttggatcgct
      841 agattaagag aacctgaaac gccatacgca gcagcaaagc caagccccaa tccaataatg
      901 aatcccatta cagagttttc agagaagatc ccaattttct tcttcaatgc attcgtatcc
      961 gctcgtttat ttaaagcagg aattttatcc atgatcatat tgaaaagcag caataagaca
     1021 gcggcagatg tcataaaatg agtcactgtt actaatggaa tccctgtgag atcttgtata
     1081 tgtttttgaa acatatcacc aagctttaat tccaatataa cttggaccat tgcagtaaga
     1141 aagcctgcag ccaaactacc ggaaacataa taaactaaat aagcagttaa agctttcccc
     1201 caaacattcc acatatcaac atttaacgtc ttcgtccaat taaaaagtaa cagtacaaaa
     1261 ttgaccccaa tcgttactgc aaaaaatata aaagcataac tccacgacca tgtgatgctt
     1321 gctgcacctg tccacccaag atcaagtgca ggcaaactga ttcccgtatt tttagccaat
     1381 gcttctgatg ctggacttac tgcgttagac atatagccaa tgaccataga cattccgcta
     1441 aaagcaatcc ctaaagtcaa agcagacagg aatgcttttt ttaatttcat ccctgccaac
     1501 aatccaagta tcaaaataat caggggaaca aaaatggctg atcctaagtt caaaacataa
     1561 ttgataatgg tttggaaaac ttccataaat aaaccttctt tctttcgaaa tatagtaaat
     1621 aaaactatga accaactttt ttatccaaca atcctccttt actgtactaa ctctttgata
     1681 ctgtcataaa taggttctac acccattcca gttaaaaatg gaattcctgg aaatacttca
     1741 atacccaaat cttttgcttg ttcaagtact tcctcatcag gttgtgcgac atacacatag
     1801 attccagcag ttagaagctc attttgaatc gatttgtaat caactgcttc tacaggaaat
     1861 gcgatgccgt catcttctaa catactttgg atcttactag cgattgtctg actcgttgct
     1921 actccacttc cacatgcgac aattaaccga tttttcattt ttt
//
LOCUS       DAFKHN010000185         1919 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFKHN010000185 DAFKHN010000000
VERSION     DAFKHN010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.193"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(33..1481)
                     /locus_tag="LY912_002956"
     CDS             complement(33..1481)
                     /locus_tag="LY912_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013189598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HBM6956559.1"
                     /translation="MDYEIQKFISEKEDQYFDRKSARIKPRDIIKHIVAFANADGGKL
                     VIGIEDDGTISGFKFQGAIDPDEYVLAINSMTKPNPTFKKEMKSIKNARGEDDILFII
                     DVEPSISHVIFNSNGDCFLRIGDKSVHQTHDQISKLEYDKGQRMFEDIEILDSTLDDI
                     DESLMDSYKKLKKAEAISTETILTGRGLMRNGHLTNAGMLLFGKNTFLALPNSRIRFL
                     RYDGKRNETGRRLNIVKEFDYEGAIPKLIESITRDVKTQLREFQYLNDDGKFSIIPEY
                     PEFAWFEGIVNALTHRDYSYKGDYVRINMYDDRLEIFSPGALPNIVTLQNMRRTRYAR
                     NPRIARTLSEFGWVKELNEGVNRIYDEMQLLFLNEPKYSEPNNNSVLLVLENSITSRH
                     LRERDRLDDYLGEFEVDSLSTSEKMIVSHLFNNEKISVKEASEVLKKGVGYSRKVLKE
                     MLRKKIIQWHGTSTKDPTQYYSLNRVKQSKIE"
     gene            complement(1627..>1919)
                     /locus_tag="LY912_002957"
     CDS             complement(1627..>1919)
                     /locus_tag="LY912_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956560.1"
                     /translation="EINLYLDKILRKFVNTPNTDIVEIWLQRLSLIHSREKSYSAKLC
                     KKVSNPKGFTLWNSDWLKKGFDESGIVNETFISNLSLTTPAKDLELFISQYE"
BASE COUNT          582 a          383 c          230 g          724 t
ORIGIN      
        1 tcttactctg tcttactcta tcttactctg tcttactcta tcttactctg ttttactcta
       61 tttaaagaat agtattgagt cggatctttg gtactagtac catgccactg aattattttt
      121 ttccttaaca tttcctttaa taccttacgg ctatatccga cccctttttt taatacttct
      181 gaagcttctt ttaccgaaat tttttcgtta ttaaataaat gtgaaacaat catcttctca
      241 gaagtagaca aagagtctac ttcaaattct ccaagataat catctagtct gtctctctct
      301 cttaaatgtc tagaggttat actattttct aagactaata aaaccgaatt attatttggc
      361 tcactatatt taggttcatt taaaaatagt aattgcattt cgtcatatat tcgattcaca
      421 ccttcattaa gttccttaac ccatccgaat tcagataatg tcctagcgat tctgggattc
      481 ctagcatacc tagttcggcg catattttgt aaagtgacta tattaggtaa agctcccggg
      541 ctaaaaattt ctaacctatc atcatacata ttaattctaa cgtaatcccc tttataagaa
      601 tagtctctat gcgttaaagc attgactata ccttcaaacc atgcaaattc aggatattca
      661 ggtatgatac taaactttcc atcatcattt aaatactgaa attctcttag ttgcgttttt
      721 acatccctag ttatagattc gattagcttt ggaattgcac cttcatagtc aaattcttta
      781 actatattta atctccgtcc agtttcatta cgcttaccat catatctcaa aaaacgaatt
      841 ctagaattag gtaaggctag aaatgtattc ttaccaaata gaagcatgcc agcatttgtc
      901 aagtgaccat ttctcattaa ccctcttcca gtgagtatgg tttctgtgga tatcgcttca
      961 gcttttttta attttttata tgaatccatg agagattcat caatatcatc aagagtactg
     1021 tctaaaattt ctatatcttc aaacattctc tgtcctttgt cgtattctag tttggatatt
     1081 tggtcatgag tttgatgaac acttttatcc ccaattctca agaaacaatc accgttcgaa
     1141 ttaaaaatca catggcttat gctaggttca acgtctataa tgaataatat atcgtcttct
     1201 cctctagcat tcttaatact cttcatttct tttttaaaag ttggattggg ttttgtcatt
     1261 gaatttatag ctagtacata ttcatctgga tcgatcgcac cttgaaattt aaacccagaa
     1321 atagtcccat catcttctat accgattacc agcttacctc catcggcatt tgcaaacgct
     1381 actatgtgtt ttataatatc tctaggctta atccgtgcac tttttctatc aaaatactga
     1441 tcttcttttt cacttataaa cttttgaatc tcataatcca tttaaaattt cccttcttaa
     1501 atttttttat tatagagccg tatattcaat ttccacaaaa aaataatcta aaacaaaaca
     1561 gacaccttca ttttgatatg ttctcccaca tatgaatcgg tcgctataca gcattacata
     1621 tagtaattat tcatactgcg aaataaatag ctccaaatct ttagctggcg tagttaagct
     1681 taaattcgaa atgaaagttt cattgactat tccactttca tcaaatccct tcttcaacca
     1741 atcagagttc cacaacgtaa atcctttagg attagaaact ttcttacata attttgcact
     1801 ataggatttc tctcttgaat gaattaaaga aagtctttgt aaccaaattt caactatatc
     1861 cgtattagga gtattaacaa attttcttaa gattttatcc aagtataagt tgatttctt
//
LOCUS       DAFKHN010000186         1833 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFKHN010000186 DAFKHN010000000
VERSION     DAFKHN010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.194"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            235..495
                     /locus_tag="LY912_002958"
     CDS             235..495
                     /locus_tag="LY912_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956561.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(857..1096)
                     /locus_tag="LY912_002959"
     CDS             complement(857..1096)
                     /locus_tag="LY912_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956562.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            1382..1696
                     /locus_tag="LY912_002960"
     CDS             1382..1696
                     /locus_tag="LY912_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956563.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          654 a          245 c          312 g          622 t
ORIGIN      
        1 aacaaaaaaa gtgagtggta tcaataaaca tacaaaaaga tattttcttt tgttaagatc
       61 agtattagtc atataaaata agagaaaaaa gaaaaagttt cccacgaaca ttcttaatag
      121 ataagctttt gtatcgatag taatcaagag atcccctcct gattttagga tatcataaaa
      181 aaaattttag ttacactttt taaataatga aaaaacatta aggatggatg aaatatgaat
      241 aacgaaacta tcattttagg aaaaaaatat atttgccaac ctattggctt gaaacaaaaa
      301 gtgattggag aagtaatcag taaattagaa aattgtgttg tgatctgcgt agacgaatat
      361 catgacgtcg atcgcaatga aatattagaa aaatgcggaa aagtagtggc aaaatatact
      421 cacgtttatg agttggaaac aacagaatat ctatataact atagcaacaa atatgaacat
      481 actttagttt cataaagatt taaataaagt gccttcaaaa gcgagaagac caagcttttg
      541 aaggcacttt atttagttgg cagtgattgt tcatgatttt tgatttattc aaaaggttcg
      601 cctagagaat ctgtctctgt aacgaggcct ggtggagaaa ctcgataaaa acctatactg
      661 ccagaactgt cctattttcg gatagacaaa ctagtagttt taaaaagatc atccgatcca
      721 atcatttcaa aaaatgcaaa actgatatca ggatcattta gctcaggctt gttatcgtaa
      781 agcatttgta aaggttgcat ttagttagga gtaaacgcga aactatcatc attatttgct
      841 gaagaagatg aagaagctaa ttcagagttt gtttgaaata aaggagacgt gctgacagtt
      901 tctttaccct gttttttgca gaggtagaaa cttttatatc ggaagtttct accggagaat
      961 ttttctcatt tgtagaaatt gttgaatcga tactattcga aatttgcgta tctgaaggta
     1021 tgttctttga tgcagaagtc ccacaagcag taagtaacaa taaatttgat aaactgataa
     1081 acagaattct tttcattatg tacacactcc ttatagtatc gtttagcata cacctatgct
     1141 cagtattagg caaaatcaat gcaaaactat caagtctttt atagtatcta ttagtcttag
     1201 taatacatat atggagaggg tgatatccca gttcaaacca gatacattgg ttaccatctg
     1261 tattaacgat tatgcctcta aacgcttttt ttatgaaaaa atttataagt gaaaacgtag
     1321 gtatgatatt atctagaggt aatttttttg ggtatttaaa tagttgctag gaggatagct
     1381 tttggatttt tacagtaatt ttatcttaat aatagcaata ttattacttc taaatatttg
     1441 gttttttgat aagagtagaa atgcagggat aggttttaga accaaacgaa gtacgtcttc
     1501 tgaaaaaaag tgggtatatt cacagactat tttttacgga ggggttattt caatcagttt
     1561 actttcttca acactttatt cttttaatgt tatagacgtt tccatgtcaa attttatatc
     1621 tattattgga atccttattt ctgcaattat tacacaacta cttcttgtgt ttgaagagaa
     1681 gtcaaaaaat aattaaagca attatgcctt ttagtacagg aattattact tcttacaaat
     1741 gtatagcgaa tgtgaagcct gctgttttaa ttgttctaga aaaacttttg agtgaacaat
     1801 tattttatgt taggatgaat taatttctct aga
//
LOCUS       DAFKHN010000187         1825 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFKHN010000187 DAFKHN010000000
VERSION     DAFKHN010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.195"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(598..888)
                     /locus_tag="LY912_002961"
     CDS             complement(598..888)
                     /locus_tag="LY912_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956564.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1096..1299)
                     /locus_tag="LY912_002962"
     CDS             complement(1096..1299)
                     /locus_tag="LY912_002962"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956565.1"
                     /translation="MNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLE
                     KAKDEVEDTADKSQQIVEEHLRK"
     gene            complement(1396..1788)
                     /locus_tag="LY912_002963"
     CDS             complement(1396..1788)
                     /locus_tag="LY912_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HBM6956566.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEIN"
BASE COUNT          491 a          355 c          282 g          697 t
ORIGIN      
        1 aagaaatcta cgatagtcaa caaaaaaaat tttcattata tccagaaaaa tttttcttag
       61 ttaaggacct atggattgca gtaatgcaga attcgtcgaa taaactgcca aagacataca
      121 atcatattgc ttttaaaatt gacgaacaag atatagattc gtttgtctca aaaatccaaa
      181 tgttaggttt aactgtcgaa ccaggacgtt ctcgtgtgaa agacgaggct tcttcaattt
      241 acttttacga ctatgataat cacctcttcg agttacatac cggtactctc caggaacgtt
      301 taaaatccta caattccact acctgagact agtaatgact agtctctttt tatggcctct
      361 gatcccccca ttgagcgaat actaataggg cttcgaattg atctgttcaa tctttaagca
      421 atatccctca aatgagtttg gaaagtttag tgattcatca caaatactta aatacatgta
      481 gttatatata gattgaggtt cttgtgagcg tatgctcgtg tgggttcaaa tcccatcgtc
      541 tgaatccatc tttccaaaac aagcggctag gacatttttg tctcagccgc ttgttttcta
      601 gtttattctt tcatcttgtc ggaccttttt tcttgggtat agacttttct catattctac
      661 cacaattttg ggtttcccta acacatgata ggatctcaca acaaattgct ttctattatt
      721 ataataacct gtaacgacta acttcatccc ttcgtctact tcagctagga agttcaaact
      781 atgggaagca atcaaacaat tgaccccatt taaactgaaa cggatcaacg gtctggcact
      841 aacttgcaaa gtacggatct tatctactgt tccatatttt ttctccataa ccttcacctc
      901 aataccatta tacgaacata cattcccttt gtaaagaaga aactctgttt tatctttttg
      961 actttttgtc tattaccttt cttaaaatca tattggcact tcctgcgaag atgaaggaca
     1021 tgtactaaaa aaaagaggca gcagtataga ttactgttgc ttctttacta atttaggttt
     1081 acttgttaag aaagattatt tacgcaaatg ttcttcaaca atttgctgag atttatcagc
     1141 tgtatcttcc acttcatctt ttgctttttc taacttttga atatattgtt tcaagcttga
     1201 gttttcagca gttgcttcgt ctaatttctt ttgtgtatct gttaactgag tttctacatt
     1261 tgttttttct tgtgtcagtg ttgcgatttg ttgattcaaa ccatttacag tattttgtaa
     1321 ttctgaaagt tttgcttgtg cttcttgtag tcttgctgtc caatctgcat tcagatgatt
     1381 gatttcatca tttttttagt tgatctcatc tagtttgaca ttgatttcat tttgcttgct
     1441 ttgtagttgt gcatccttgc tgactaattg actttctaag ttttgttttt ctgctgccga
     1501 ttgatttttt tggttttcta attcatttac ttttgtttgg tattcttgga catctgcctt
     1561 tgaatcttgc aatgtctgtt ctttttgtgc tagtcgagcg gtaagatctg taatcgcttg
     1621 ctctttatct gtcaatgtat gatcaagctg tgtcagattc tcattgattg tatcaatatc
     1681 tgtctctcca ccccacaaaa taatttcatt tgcgtaccgc gtgcctgtgt agccaattag
     1741 acatagaaat gcaacgacaa tcccaccagt aataaatttc tttttcattt gcatagctcc
     1801 ttaatccaat acttttacat actaa
//
LOCUS       DAFKHN010000188         1775 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFKHN010000188 DAFKHN010000000
VERSION     DAFKHN010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.196"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1632
                     /locus_tag="LY912_002964"
     CDS             <1..1632
                     /locus_tag="LY912_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBM6956567.1"
                     /translation="NYTEEQYNIEKEKALKVGYSEEQFKQIMEIPTNLSNENSETRIV
                     NYTMTSNQTKVINKAMEQIGKPYEWGASGPNSFDCGGLVKYVYKQAVNIELPMGTTNQ
                     EQYGTEVSLNSLKPGDLLFYGNRGATYHVGIYKGNGVMIHAPQPGETVKEVNIQYFYP
                     NFAKRILPDEPDYPYIDYNKMVTVTKAWSIWNDLQFSHEIKKAIIGDNYKIGKVYTNP
                     ENNNKYGEILVSNKVYGYINFYAVKELTSVQINRYLTSKDSGQPTWGNLECTISKGQT
                     TKDKIYFVKGAYNLGDGKYLYSIYKDQDSSEWLGYLKAHVSLAYTPIEEINKNVTVTK
                     NWSIWNNLQWEKEIEKPQIGSVFSARLKLTNVSNNAVYYKLYKSGKFYGYINAEAVKD
                     LTTTKLNKYVTFSVNNEDFWSSLDVNYSKGKTERGRVFYISISYNTADNQPIYSVYTD
                     ETCTEWRGYYKGNNFEDTQITMLENKSVKVTKSGYTVWGDLNFWTKSGISNTGDIYTT
                     DRKFYNFTNNAYYYELKKDGRVYGYINSEAAVEMN"
BASE COUNT          691 a          218 c          323 g          543 t
ORIGIN      
        1 aactacacag aagaacagta taatatagaa aaagaaaaag ctttaaaagt tggttatagt
       61 gaagaacagt ttaagcagat tatggaaata cctacaaatt tatcaaatga aaatagtgaa
      121 acaagaatag taaattatac tatgacttct aatcaaacca aagtcattaa taaagcaatg
      181 gagcaaattg gaaagccata cgaatgggga gcatcgggac caaattcttt tgactgtggt
      241 ggtttagtga aatatgttta caaacaagct gtaaatattg aactgcctat gggaaccacc
      301 aatcaagagc aatacggtac agaggtaagt ttaaattcac ttaagcctgg tgatttatta
      361 ttttacggca atcgaggtgc aacttatcat gtaggtatat ataaaggtaa cggtgtaatg
      421 attcatgcac cgcaacctgg agaaactgta aaagaggtta acatacaata tttttatcct
      481 aactttgcaa aaagaatttt gcctgatgaa cctgactacc cttatattga ctataataaa
      541 atggtaactg ttacaaaagc ttggtcaata tggaatgatt tacaatttag tcatgaaatt
      601 aagaaagcta ttattggaga taattacaag atagggaagg tttatactaa tccagaaaat
      661 aataataaat atggagaaat attagtaagt aataaagtat atggatacat taatttttat
      721 gctgttaaag agttgacctc tgttcaaata aacagatatt taacttctaa agatagtggt
      781 caaccaactt ggggaaatct agagtgtact ataagtaaag gacaaactac aaaagataaa
      841 atatattttg ttaaaggagc atataattta ggggatggaa agtatctata ttctatttat
      901 aaagatcagg attcctctga atggttaggg tatttaaaag cacatgttag tttagcctat
      961 actcctattg aagaaattaa taaaaacgta actgttacta aaaattggtc gatttggaat
     1021 aatctacaat gggaaaagga aattgaaaag cctcagattg gttctgtatt ttcagctaga
     1081 ttaaagttaa ccaatgtatc gaataatgct gtctattaca agctttataa atctggaaaa
     1141 ttttatggtt atatcaatgc tgaggctgtc aaagacctta caacaacaaa gcttaataag
     1201 tatgttacat ttagtgttaa taatgaagat ttttggtctt ctttagatgt aaattattca
     1261 aaaggaaaaa ctgaaagagg ccgagtattt tacattagta tttcatataa taccgcagat
     1321 aaccaaccga tttattcagt atatacagat gaaacatgta cggaatggcg agggtattat
     1381 aagggaaaca actttgaaga cactcaaatt actatgcttg agaataaaag cgtgaaagta
     1441 acaaaaagtg ggtatacagt atggggagac ttgaattttt ggactaagtc aggaatatcg
     1501 aacacaggag atatatacac cactgaccga aaattttata attttaccaa caatgcttac
     1561 tattatgaat tgaaaaaaga tgggagggtc tatggctata taaatagtga agcagctgta
     1621 gagatgaact aaaatattgc tgtcccttaa tcttatgggg cagcaatatt tttatattat
     1681 taatcatttt tctgaagcga gggtagaaga attaatcaat agtttttctt gttttgtaat
     1741 ataatagttt aattaccaaa aattatttaa gtaaa
//
LOCUS       DAFKHN010000189         1687 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFKHN010000189 DAFKHN010000000
VERSION     DAFKHN010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.197"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(594..>1687)
                     /locus_tag="LY912_002965"
     CDS             complement(594..>1687)
                     /locus_tag="LY912_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBM6956568.1"
                     /translation="SLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQNTFSK
                     IWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLSFVGK
                     ISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKMRSPK
                     IWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKKILFI
                     GDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLGTNGV
                     ITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYSESKN
                     HPEFFYDDETHLNESGRTAYAKYIASVIQ"
BASE COUNT          543 a          312 c          243 g          589 t
ORIGIN      
        1 taacttttga atagagtaac taaattcaaa agctattata gtataaaaat acactttttg
       61 ttgttcaaat ttttcatcta attgtgcagt aattttgaac tctatatttt ttaatattta
      121 atgcttaagc aatcatttat aaaaaaagac tggacgataa ttaaaataac aaaaaaggct
      181 gtgacacgtc ttttgtcaca gtcccttcta gcattatatt actattattt attcactgca
      241 tcttcttaag agtaaaacat acttgatcgt ttgtttcttt actaacagcc ttctttactt
      301 ggttcctacg atccttaatt ttatctaagc tgattgctgc ttgtaaccat aaaacttcga
      361 tcagaacata catcctagta ttgtcgtctc gctcatgttc tgtataacaa agaggataaa
      421 tccaaagcga tttctttcca agaagctctc agttaacgac ctcgcccatc tcttttttac
      481 cacgaatatt aaaaagctcc tcctcttaaa caccgtttat catatgaagt attttttatt
      541 taaattgatt cacctattag gaaaaagtaa ggttaacaca cgtaatcact accttattga
      601 ataactgaag caatatactt tgcataagct gtacgtccac tttcattcaa atgggtttca
      661 tcatcataaa aaaattcagg atgatttttg ctctcactat accaatcgat catcgttata
      721 ttagaatact gatttggcaa tgtagctaat gtggcattta tcgtatcttg ccagccagtt
      781 ggtgctttta tatttaccca gtatactttt ttatctttca gcaaagacat tgtttgttct
      841 atagcttcat ctgttatcac accattggtt cctaacccga tcactatttg ttggtaagaa
      901 actaaatctt tatgctcctt taagatttct ggtaacgcag tgatttgtct tgattctttt
      961 gcatctacca atgcttcttt tttaaatgtc tcctttagtt cctgatacgc ccccagcata
     1021 acagaatcac cgataaataa tattttcttc tcttgtgaca acagattttc tcctgcattt
     1081 gctttactag agttttcttt taataaactt tgcaactgat tttggtcagc ggtcagtcga
     1141 ctggcaggag cacgtaatac cagtacagaa actccgatta tcattagtgc catagctgtc
     1201 caaattttgg gtgatctcat cttttgcact ccttttctaa agcaagtaat catgagtaat
     1261 gtacataaaa acacagtgaa tagacctgcg atatccaaat atttccaatg gtgatgtttg
     1321 aatagatttg tcagagcaat caatactggg aaatgcacca aataaagttc ataactgatt
     1381 tttcctacaa aagaaagttt tgtactagcg attttggtct tttttgcaat gttcatatca
     1441 tcgacactgg ctaacaatag agcaaaacaa atactgatca gtagttcatt tagtgtataa
     1501 ggaaaaatcg ggaacagaat cagacaaaga ctagctagta ataaaagcca gattttacta
     1561 aaagtgtttt gttcaaagaa acggccaata gttattcgat taaaataccc ccaaactcct
     1621 aataaaaatg gaaaaagttt agctatcgta tgataatatg ccttagttga aggtaaaaac
     1681 aaactaa
//
LOCUS       DAFKHN010000190         1686 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFKHN010000190 DAFKHN010000000
VERSION     DAFKHN010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.198"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            186..410
                     /locus_tag="LY912_002966"
     CDS             186..410
                     /locus_tag="LY912_002966"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956569.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            414..599
                     /locus_tag="LY912_002967"
                     /pseudo
     CDS             414..599
                     /locus_tag="LY912_002967"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            793..963
                     /locus_tag="LY912_002968"
     CDS             793..963
                     /locus_tag="LY912_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956570.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1387..>1686)
                     /locus_tag="LY912_002969"
     CDS             complement(1387..>1686)
                     /locus_tag="LY912_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBM6956571.1"
                     /translation="DGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKEN
                     RKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT          518 a          309 c          272 g          587 t
ORIGIN      
        1 tcctttcttt ttacttttat tttttacagt catctatgac aggttgtaaa tactatggaa
       61 catcatatgg cgttgtcatt ttcttgtcaa ctatttttcc tattcatgtt tttataaaaa
      121 aacatatcgt tttcttgtat gattaaatca ccacaaaata aacaactgag agaacgatat
      181 gctttatgaa tggttctatc aaaaaaattc tgagatcaat agacaaaaat ttgatgatta
      241 cagaggtctc ttacgaaacc ttacagaaga aaaaaacatt gatcgttgct gcagttctct
      301 tccctgctcc atgtgtctgt agaaattgtg gttctgctgt ggtagatgga aataggaaat
      361 taatggtggt gaaaaacaag aagaaggaaa ccattgtcca ctttgaataa tataatcata
      421 tgccaatggt tatacgccta aaaaagcagc gctatacctg taaaaactgt cgaagccatt
      481 ggaacgctca aagttatttt atccgtccaa ggcactcgat ttcaaatcat gtcagacata
      541 aaatcacttc tttactgact gaaaaagtgt cgttattttt tatttcgaaa agttgttagg
      601 tatctttgac aaccgttatt cgcacattga aagagttgag aagctattta ccaaagtctt
      661 ccaaaagaat tctgtcttga gtgttgaggg ttgtgaattt cgttctcacg tttccgttga
      721 ggataaactg agttttattt ccgcggatgg cgagacagaa aaattaatcg agaaaattta
      781 cctacacaaa aaattcctcg attaacaaac tatttcctta gctgcactaa tcctaaagaa
      841 atagaattct tagttacaga catgaacgcc acctactttc agctcaccaa acatgttcta
      901 ccaaatgcga aattggtgat tgatcgatta cttggttttt ccacgccttt caaggaggcg
      961 taacctttat tcacgagttg gttgaagctt tccgagacaa aagacccgac ttgtttttct
     1021 ccttattgac aaagagccat taaaactaga gaaaaaatta caactgatcg ctgattattt
     1081 gtagaaagaa aatcaaagta ttacccaata aacttgagtc attaggcaaa aaacactgcg
     1141 aaactcaaga atgattttcg cagtgttttt gtatattttt tattaactag tattactaca
     1201 aaggtttatt tttcacttct caacgcagca caaaattgtc tttacttatt tactggttgg
     1261 gttcaacctt ctctactccg atactaatat ttgtttgtat accccttcta aaatcggtag
     1321 tttccattca attgatgggt actagttgat tttaaaaact atgcttattc aattttttat
     1381 tttagctcat atatttcgtt tctttctaaa ttttatactg atgaaaacaa gtagcacacc
     1441 caatattgac aatataaact ggctaatgat ggtttctcca gtttttggaa gatgcttatt
     1501 tccactgctt gttggattgt ttcctcttat atctgagcta tcagcaactt ttctattctc
     1561 ttttgttaaa aagatcgcca cttcttgttc tttttcgatc ttgaaagtta ctggtgtcgc
     1621 atccaattca taccccgttg gcgcttgagt ttctaccagc tgatatgctc ctggtgctaa
     1681 gccatc
//
LOCUS       DAFKHN010000191         1684 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFKHN010000191 DAFKHN010000000
VERSION     DAFKHN010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1684
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.199"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            716..1189
                     /locus_tag="LY912_002970"
     CDS             716..1189
                     /locus_tag="LY912_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBM6956572.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1198..1425
                     /locus_tag="LY912_002971"
     CDS             1198..1425
                     /locus_tag="LY912_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956573.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          551 a          279 c          254 g          600 t
ORIGIN      
        1 ttggactact acattatggg aatctctatt ctttttcatc ttcgtatttt tgttacaaaa
       61 ttatcgaaaa aaataaacat gtgccatcta tctgttggca catgttttag gatttatggt
      121 actttttatt cggcaatcca ttttattttt ctacttcttc ttaatacctc taacactttt
      181 gatttataaa ctaatccaat gcatctactt gcgcttatta agctatttca gctagatagt
      241 accaccccat gcgtcaatgc ttgattttcc ttttgtataa cattgtataa gcaataaagg
      301 acaaataagt ggtgattaca ccaaaccatt gaataagaaa aattctgata cgtaaataaa
      361 catgaacttg aaaaaattaa tgaatcggtt agctactacg tagttgtctt ttttctcata
      421 cagttctgtt aacttacact tctcttcgct agataataaa aaatcctcca actgtattgt
      481 ccaatataat cccaggcatc taaactagca ttatagaaga gacacacata gaatctaaaa
      541 taactggttt taaatgtttc ttacaatcaa aaaaagctgt taaatgcact ccacaccttc
      601 atactctatc attttttata aacgatatat ttttattgtt tttcgataaa aaatagttgt
      661 tttacaataa ttattctgct atattttagc tatcaaagat aaaagaggga taaaaatgaa
      721 atttaaaaca ttgctattaa aatttgtcgt tttaggtata agtgccgtat ttattttgtt
      781 cggcgtactt ttttatactc agatcgctac aagcgaaaaa ggattcaatt ttgattggca
      841 gaccacatta tttgtttctg tcatttactt tgcccttctc ctagggatcg ttattgctta
      901 tttcttattg aaactattga aaaaaatcga agataaccaa gctttttcca ctcaaagctt
      961 aaacatacta aaaaaaatcg aacgaaccat tttgtttatt ggtttcgcct tttttggctt
     1021 acttcctaaa tttatgaaag tagcggattt agacgatgct ccaggtttga tgttggtagg
     1081 aatcgctgtc gtattcattc cttttgcagt atacacatta acaagcgtgc tggaaaaact
     1141 gcttgaacat gcgattttac ttaagacaga tcatgatttg acagtgtgag gtgcgacatg
     1201 gcaattatcg ttaatttaga tgtagtatta gctcaaaaaa aaatgagtgt gactgaattg
     1261 agtgagaaag tgggcattac gatggcaaac atctctattc taaaaaatgg aaaagcaaaa
     1321 gccatccgtt tttccactct cgaaaaaatc tgccaagttt tggagtgtca accaggtgat
     1381 ttgttgacct ataaaaatga ctcgaatact ataccagaag aataaaataa agtagaacaa
     1441 acagtaaata aaaaataatc tgaatgatag atgtgtgaga cttttagaag ttatttacgt
     1501 ctattattca gattttttat ttcgattgaa taccgtttta tctataaata agatatgtac
     1561 tgactcatac aaagggggcc ttttcttctc catgtactat cacttttcct gatacaactg
     1621 gtttcctgtt acgttgtagt tggatctgct tttagtataa tactttattc attccaccag
     1681 actg
//
LOCUS       DAFKHN010000192         1650 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFKHN010000192 DAFKHN010000000
VERSION     DAFKHN010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.201"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            2..412
                     /gene="spx"
                     /locus_tag="LY912_002972"
     CDS             2..412
                     /gene="spx"
                     /locus_tag="LY912_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBM6956574.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            426..782
                     /locus_tag="LY912_002973"
     CDS             426..782
                     /locus_tag="LY912_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBM6956575.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            1455..>1650
                     /locus_tag="LY912_002974"
     rRNA            1455..>1650
                     /locus_tag="LY912_002974"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          587 a          266 c          322 g          475 t
ORIGIN      
        1 aatgataaaa gtatatactt cgcctagctg tacttcctgt agaaaagcaa gagcatggtt
       61 gcaagcgaat caacttgaat ttgaagagaa gaatattttt gccgaaccgt taacagaaag
      121 tgagatcaaa aagatcttgg cagcgactga aggaggagtt caagatatta tttccactcg
      181 gtcgaaaatt tacgaaaagc tgggcataga ttttaacgaa ttaactttaa agcaaatgat
      241 cgtcttattc aaagaatatc cttcattatt gagacgacct attttgattg atgaaaaaag
      301 aatactaatc ggatttaatg aagatgagat ccggtcattt gtccctcgtg aaattcgatg
      361 tgttgccaga aatctgatct atttacaaaa caataacatc ttaaattcat agggagggag
      421 ccttcgtgga agtgaaagtc tatggatcag cgcactgtgt aacaagtctg aaggcgaaac
      481 aatggttaga acaccatcaa ttgccttatc aatttgttga cttagaagaa cgcgatctaa
      541 gtacagaaga agcagaagaa ttatgcagtt ttgaagaagt gcaagcagaa cagctatttg
      601 cgacttggtc tgaggctttt cacaacattg cgattgacct ttcctgtgta ggaaaaaaac
      661 aactgatttt tttatgcaca caacatacca atctcctcag acgtcctttg attattatcg
      721 atgaagttct atttattgga tacaatgagc agttgatgga acagcttatc ttaaataaat
      781 agactttaac tgttttaatc aagtcactga gcatttcata cagttgtaac agtcgaacac
      841 ttagcatcaa gcgtgttatg tgttcttttt ttgactttat ttttctacta tagagacatg
      901 ctcaatttat gtggtcaaaa ttcaaatcta ggtggggata tagagttaaa aatatattga
      961 catgtgtaaa tttacatgat atattcattt ctgttgtttt aagtagcaaa gcaataaaat
     1021 agtattttaa aaaacatata aaatagttgt tgacatgtta gaaatgacat gataagataa
     1081 ctgagttgtt aaaaaagaac cacttgtgaa gcttgattct atcgaaaaaa acttcaaaaa
     1141 agttcttgac aaataacaaa tgataagtta tgataaatga gttgctgtaa gatttcgaaa
     1201 aacgaaatca aaaaaacttt taaaaaagag ttgacaatta cttgtctctc tgatatgata
     1261 taaaagttgc tacggcagcc aaaaacgaat cggggaacac tcctgatgaa gtagaccttt
     1321 gaaaactgaa caaagtaaga caaaccaaat gtgtagggcg tcttgattca attcaagaca
     1381 acaaacattt tttaacaagc aagcaatatg ctagcaaaca aattgagctt aacaatcgca
     1441 agattgttcg aactttttat gagagtttga tcctggctca ggacgaacgc tggcggcgtg
     1501 cctaatacat gcaagtcgaa cgcttctttt tccaccggag cttgctccac cggaaaaaga
     1561 ggagtggcga acgggtgagt aacacgtggg taacctgccc atcagaaggg gataacactt
     1621 ggaaacaggt gctaataccg tataacaatc
//
LOCUS       DAFKHN010000193         1625 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFKHN010000193 DAFKHN010000000
VERSION     DAFKHN010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.202"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            1..1152
                     /locus_tag="LY912_002975"
     CDS             1..1152
                     /locus_tag="LY912_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBM6956576.1"
                     /translation="MASEKYQKTFPNRQLAIKAENDMKKKIEKVLREENANSLELKGK
                     ITFKKFYESKWLPRYELGQTIRSNRPPSDITISNTKDIFRLHILPMFGEYAMNYLNIN
                     TEIISDELTKKSKEYANIKIIKGYVRSMFDIAEILNYIEFNRTTKIIQSITAPKKNAL
                     EEKRIQEGKQALSSKELTNWIEAVNDDFNNHLLTFHDYTLFMITLYLGDRKSETYALQ
                     WKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTVIQVPEVVMTLLSEWKSVQADQLLKL
                     KIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRINSIKRRHPDLVHLSPHKLRHTYATI
                     ARQGGADMNQISNALTHSDISTTKIYVNTPDIVDKAVFEAFQRGLNKCD"
BASE COUNT          597 a          257 c          243 g          528 t
ORIGIN      
        1 attgcatcag aaaagtatca aaaaacattt ccaaataggc aattggcgat taaagccgaa
       61 aatgatatga agaagaaaat agaaaaagtt ttgagagagg agaatgcaaa ctcattagaa
      121 ttaaaaggaa aaataacgtt taaaaaattt tacgaatcta aatggcttcc tagatatgaa
      181 ttaggtcaaa caattagatc aaacaggcct cctagtgata taaccattag taatacaaaa
      241 gatatatttc ggttgcatat tttacctatg tttggtgaat acgcaatgaa ttatctaaat
      301 atcaatactg agataatatc agatgaatta accaaaaaat cgaaagaata tgcaaatata
      361 aaaatcataa aaggatatgt tcgttccatg ttcgatattg cagaaatact aaattatatc
      421 gaatttaatc gaactactaa aattattcaa agtatcactg cacctaaaaa aaatgcttta
      481 gaagaaaaaa gaatacaaga aggtaagcaa gcactatcat caaaagaact tactaattgg
      541 atagaagcag taaatgatga ttttaataat catttactta cttttcatga ttacacactt
      601 tttatgatta ccctgtatct tggtgataga aaaagtgaga cttacgcttt gcaatggaaa
      661 tatattgatt ttgaaaaaca aacggtccgt cttaaacata ctttagataa atatcaaaga
      721 aaaaagttta caaaaggtcg aaaagatacc gtcattcaag taccagaagt tgtaatgaca
      781 ttgctaagtg aatggaaatc ggtacaagct gatcaattgt tgaaattaaa aattaagcaa
      841 acgttagatc agtatctctt tacttatact aaaccatctg gagaagtaaa ttgtcctgtt
      901 catgccgatt acctaaacta tcgaatcaat tcaattaaaa gaaggcatcc tgacttagtt
      961 catttatctc cacacaaact ccgtcatact tatgcaacta tagctagaca aggtggagca
     1021 gatatgaatc aaatttcaaa tgctttaaca cactcagata tttctacaac aaagatatat
     1081 gtgaacacac cagatatagt tgataaggct gtttttgaag cttttcagag aggattgaat
     1141 aagtgtgatt gatatgtgtt cttaaatgtg ttcttaaaaa caaaagaagc actttccaaa
     1201 taattgaaaa gtgccagaaa cgttgatata taaaggatat taacgttttg agaattgtga
     1261 agctttacgt gctttcttaa gacctggtta aacaaacttt tcatttataa tgttttacag
     1321 agatatatgt cgtatgaaat taatgttctc ttgttcatga agttttacag aattgtatag
     1381 ggttatctgt tgtcattacc tcaaatcatt accacaactt ggcgagttgg ctgattgaag
     1441 aagtactctg ttttactcta tcttactctg ctttactcta tcttactctg ctttactcta
     1501 gcttactctg ctttactcta gcttactcta tcttactcta tcttactctg ctttactcta
     1561 tcttactctg ctttactcta gcttactctg ctttactcta tcttactctg ctttactcta
     1621 tctta
//
LOCUS       DAFKHN010000194         1598 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFKHN010000194 DAFKHN010000000
VERSION     DAFKHN010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.203"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1087
                     /locus_tag="LY912_002976"
     CDS             <1..1087
                     /locus_tag="LY912_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBM6956577.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..>1598)
                     /locus_tag="LY912_002977"
     CDS             complement(1305..>1598)
                     /locus_tag="LY912_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBM6956578.1"
                     /translation="SIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLR
                     HSHVAFLIEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
BASE COUNT          560 a          281 c          297 g          460 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattga
//
LOCUS       DAFKHN010000195         1589 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFKHN010000195 DAFKHN010000000
VERSION     DAFKHN010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.204"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            89..940
                     /locus_tag="LY912_002978"
     CDS             89..940
                     /locus_tag="LY912_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956579.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            961..1244
                     /locus_tag="LY912_002979"
                     /pseudo
     CDS             961..1244
                     /locus_tag="LY912_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          595 a          207 c          320 g          467 t
ORIGIN      
        1 acttaaaaaa ttggttcatt gagcaaccta tcgctgctaa agtagcaaag gaaaacgtta
       61 aaggaaagaa tttagggaag aaatcgaaat gaaatcggac gactggattg aacacacctg
      121 gcttcctctg aaaagaaata gcaaacgaaa gaaattttgg gtattgcaat tatggccatt
      181 aggaaaactt tgtagttacg gggcacgact tattcttgat ttaaccgttt actcgattgg
      241 agtatttgga acggcttatt acttgataaa tgatcccaat aggattgcag catcagacat
      301 ttttacagtg ctaatgacgt tgatttttgt catgctattg tctattttta ctcaattagt
      361 catgcaattt accaggcaaa aattaacagc aggaaaactt ttcaaaagcc tattcgattt
      421 aattgttgta aatgcaattc tagcgacttt aataaaacaa attgaacaat ctggaagaac
      481 aacaaaagga gtgaaggatt ttttattgac gtttattcac tttgtaaatg gacacatgta
      541 tttgtttgaa gtgggtatta ttctcttttt tgtcgggtat gtatccacga aacttattaa
      601 acgttcaatt gaaaaagaaa ttgaaattga cctgattccg acacttcttg gttatgagta
      661 caatgttgat tttggaagat atgacgaatt gatcaatacg gatatcgttc acacgagtat
      721 ccatgaatct actgttaagg gcatcagatc tattttaaaa aatggccagg aaatgaaagc
      781 aatagatcga agaaaagaga tctacaattt ttatgaagtc gaagcaagcc tacgatatgg
      841 catcggaaaa ttgtggttag atggaagtaa tattcgtcaa aacaaaccat acattttttg
      901 gaacagtagt gatttagaac ttccaatgaa agataaataa ttatggagaa tcgtttgaaa
      961 atgattcctc tatacaggat tgtgcttata gttggcatgg agttaaaaac cttaaagaag
     1021 gagcagttat tcaaagtgaa agaacgtcat aatcagttac tatgtagtaa aacgggtacg
     1081 atgaacattg aataccgaac agaatattta gaattaacga atcaaactga ttttttgttg
     1141 attcgaaagc aacaagagca agaaaaaaat taatggctac ttatagccaa ttgattgatg
     1201 aatgggaaca attcaaggaa tctaaaattc cagaacgtct ctaaaagcct ttatttgtaa
     1261 agagcataag gaaacgtggg aacacttttt aaaaaaagtg ttccaatagg ctgtgcctat
     1321 tacgtttctc aaaaataaat gtgggaacaa aatatttaaa aataggatag tgaaaggata
     1381 gtgaaggata gtaaaaggag ggtagtagga tagcaaaaag gataggctcc ttttcgctat
     1441 cctttttaaa ttggaggaat taatatggaa gtaagaataa gaaatgtgga tgagaaaatc
     1501 gtaagagaaa ttgatcgaag atgtgacgaa cggttctgtt gcaaagtttt aaatctacta
     1561 tcaaataagg tagaataata gaaaaagat
//
LOCUS       DAFKHN010000196         1536 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFKHN010000196 DAFKHN010000000
VERSION     DAFKHN010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.206"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..>1536)
                     /locus_tag="LY912_002980"
     rRNA            complement(<1..>1536)
                     /locus_tag="LY912_002980"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          321 a          476 c          337 g          402 t
ORIGIN      
        1 gggaaatctc atcttgaggt gggcttcaca cttagatgct ttcagcgttt atcccttccc
       61 tacatagcta cccagcaatg cccttggcag aacaactggt acaccagcgg taagtccatc
      121 ccggtcctct cgtactaagg acagctcctc tcaaatttcc aacgcccgcg acggataggg
      181 accgaactgt ctcacgacgt tctgaaccca gctcgcgtgc cgctttaatg ggcgaacagc
      241 ccaacccttg ggaccgacta cagccccagg atgcgacgag ccgacatcga ggtgccaaac
      301 ctccccgtcg atgtggactc ttgggggaga taagcctgtt atccccaggg tagcttttat
      361 ccgttgagcg atggcccttc catgcggaac caccggatca ctaagcccga ctttcgtccc
      421 tgctcgactt gttggtctcg cagtcaagct cccttctgcc tttacactct tcgaatgatt
      481 tccaaccatt ctgagggaac ctttgggcgc ctccgttacc ttttaggagg cgaccgcccc
      541 agtcaaactg cccatctgac actgtctccc accacgatta gtggtgcggg ttagagtggc
      601 cataacgcag gggtagtatc ccaccagcgc ctccatcgaa actagcgttc cgatttctac
      661 ggctcctacc tatcctgtac atgcggtaca gacactcaat atcaaactac agtaaagctc
      721 catggggtct ttccgtcctg tcgcgggtaa cctgcatctt cacaggtact aaaatttcac
      781 cgagtctctc gttgagacag tgcccaaatc gttacgcctt tcgtgcgggt cggaacttac
      841 ccgacaagga atttcgctac cttaggaccg ttatagttac ggccgccgtt tactggggct
      901 tcaattcgta ccttcgcttg cgctaagcac tcctcttaac cttccagcac cgggcaggcg
      961 tcagccccta tacttcatct tacgattttg cagagacctg tgtttttgat aaacagtcgc
     1021 ttgggcctat tcactgcggc tgatcgtatg atcagcaccc cttctcccga agttacgggg
     1081 tcattttgcc gagttcctta acgagagttc tctcgctcac cttaggattc tctcctcgac
     1141 tacctgtgtc ggtttgcggt acgggccgct gttttctcac tagaagcttt tctcggcagt
     1201 gtgacatcag gaacttcggt actattattt ccctccccat cacagcttgt ccttaagaaa
     1261 agaagcattt gactcctctt cagacttact gcttggacag acatttccga tcgtctgcat
     1321 tccttagcct cctgcgtccc tccattgctc aaacaaaaac aacgggtaca ggaatatcaa
     1381 cctgttatcc atcgcctacg cctgtcggcc tcggcttagg tcccgactaa ccctgggcgg
     1441 acgagccttc cccaggaaac cttagtcatt cggtggacag gattctcacc tgtctttcgc
     1501 tactcatacc ggcattctca cttctaagcg ctccag
//
LOCUS       DAFKHN010000197         1524 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFKHN010000197 DAFKHN010000000
VERSION     DAFKHN010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.207"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            124..1500
                     /locus_tag="LY912_002981"
     CDS             124..1500
                     /locus_tag="LY912_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBM6956580.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
BASE COUNT          500 a          184 c          289 g          551 t
ORIGIN      
        1 ttaggagaaa aaacaaataa tactctgaaa tgtaaaaaat aaatactgac tctttacgct
       61 tcagagtata gtacgtactt tcatcagaat gaaaacgctt aacaacagaa gggagagaat
      121 tgtatggaaa gaaaatttgg tataagagac aaaataggat atatgtttgg agattttgga
      181 aacgatttta ctttcatttt tgctagttct tttttaatga tcttttatac aaaagtattg
      241 gggataagcg gagctgccgt tggaacatta tttttagtag caagatttat cgatgcagtt
      301 actgatgtaa ctatggggcg tattgttgat agatcgaaag caactaagca gggtaagttt
      361 aaaccgtgga ttttaagaat gagtggtcca gtcgctttag caagtttttt aatgtatcaa
      421 acttctatga tttcagcttc tatgagcgtt aaggtagtat acatgtatgt tacgtatata
      481 ttatggggga gtatttttta cacatctata aatattcctt atggatcaat ggcatcagct
      541 attacttcta ttacagaaga aagaacaatg ctatcgacat tccgaaatgt tggagctact
      601 ttagcaagtt tggtcattgg tgtattaaca ccattattta tttatacaag agatgattca
      661 ggcgctcaaa tagttcgtgg tggatcaact tttacaattg ttgcgggaat attttcgata
      721 tgtgcactta tttgttattt aatatgttat aaactaacta ctgaacgagt aagaattgac
      781 caatctcaat acaaagtttc attgttaaaa tctttaaaag ggttagttaa aaatagggca
      841 ttactttcta taattggtgc ggctattttc ttactccttg ctcaattatt aattatgagt
      901 atgaataatt atgtatttcc tgattactat aatgatgcac agggaatagt tttaatgaat
      961 tttatcaatc ctattttggt tttaatagtt gtttcgcctt taactttgtt tttaagtaaa
     1021 aaatatggaa aaaaagaact ggcatcagta ggaatgttct tttcagcaat agtatatttg
     1081 atcttatttt tgataaaagc tagtaatatg tatgtattct taattcttag ttcggttggc
     1141 tatatgggtt tgggtgtgtt taatactgtt atttgggcaa atattactga tgttattgat
     1201 gatcaagaag taaagtctga tcaaagagaa gatgggaccg tatatgcggt atattctttt
     1261 gctagaaaaa taggtcaagc tctagctgga ggcgtcggag gttggactct ttctattata
     1321 ggctatgact ctttagcaaa tgtacaaacg ggagatgttt tagaaaagtt atataacgct
     1381 tcaacattaa ttccatcaat ttgttttctg attgtaggat taattttatt tttcctttat
     1441 ccattatcta aagataaagt cttagaaaat tgcgagcttt taaaacaaaa acataaatag
     1501 gagagaaata tgaataattg gata
//
LOCUS       DAFKHN010000198         1523 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFKHN010000198 DAFKHN010000000
VERSION     DAFKHN010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.208"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            144..758
                     /locus_tag="LY912_002982"
     CDS             144..758
                     /locus_tag="LY912_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956581.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(782..1132)
                     /locus_tag="LY912_002983"
     CDS             complement(782..1132)
                     /locus_tag="LY912_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBM6956582.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1126..1389)
                     /locus_tag="LY912_002984"
     CDS             complement(1126..1389)
                     /locus_tag="LY912_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBM6956583.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
BASE COUNT          491 a          283 c          236 g          513 t
ORIGIN      
        1 tgacacatac tatttcctcc atcattagtt tttgtctata taaggtatac cctaactaga
       61 cacgaccgcg acattgaaaa atctggtttt ctcgtgtatg attagggtgt tttttaaata
      121 gttgcagaaa gtaggtaaaa attttgagag ttgcatacat acgtgtctca tccatcgatc
      181 aaaatgaaca acggcagatt gaagaaatga aaaaattcgg tgcagagaga attttcattg
      241 agaaacaatc tggcgcaacg attactcatc gacctgtttt tcaagaagca ctggatttcg
      301 tccgagatca agatattttt attgtggaag ctattgatcg acttggaaga aattacgacg
      361 agatcatcgc ttcagtcaat tacttgaaga agaaaaatgt gcagctgatc atcacaagtc
      421 taccgatcat ggccgaagca attggcaatc ctctcctgga taaattcatt aaagatttga
      481 tcattcaaat tttggccatg atcgctgaac aagaacgtac cgaatctaaa cgacgtcagg
      541 cacaaggcat taagattgca aaagcgaacg gtgtttataa aggacgtcct aagctataca
      601 gtgccaatgc aaaagatccc caacgtcgtc ttgtttataa aaacatcgtt gaggatctaa
      661 aaaaaggtgt tgcgatcgct aagattgcaa aagactacaa tgttacgaga caaaccgtat
      721 atagaataaa aaaagacagc atggtcaatc acgaatagtt gatcatgctg ctgtttctat
      781 tttatttgct tactttttga aaaactgttc taactttcat caataactcc tcaactaaac
      841 tatcatgcgc tttttccaaa aaaatacact ctctggcttc ataatcaatt gtcgttagtt
      901 gatctaataa tacttttcct gttgtcttca tttcatattc tgagtttata tttacatata
      961 gcggatagtt tctagttgta ctagaaattg gagcaactgt aacaacgtta ctataatccg
     1021 caataatatc atgacttaaa acaatataag gtcttttacc tgtctgttcg tgtccagatc
     1081 gaggtgctgt attcaataat agaatatcgc cttgtctagg ttttctcacc atttttcatt
     1141 acctactgct tcacctaaat tttgaatcgt cacatgattt ctttcatcag tgtaattttc
     1201 aaataactgt tcaattgtta attcattttc tatattagcc gcttcgataa ttagccgctt
     1261 ctgaccgttt acttcttctt gtattatctt cactttgtct tctgtatgaa ttccaagata
     1321 ttccataata tactttggca atctaaggcc attactattt ccccattttt ttataggtaa
     1381 catttccata gtagacacct ctttctgtat atacatagta taacatacat aagaaaaaac
     1441 gtatatactt aattatcctt ttctattaaa ttagattaac attccatgaa tccataaact
     1501 atgttaacat ttatatgaaa ata
//
LOCUS       DAFKHN010000199         1510 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFKHN010000199 DAFKHN010000000
VERSION     DAFKHN010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.209"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            178..1509
                     /locus_tag="LY912_002985"
     CDS             178..1509
                     /locus_tag="LY912_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956584.1"
                     /translation="MELLEKAYSSTELIDSYEYEDLKYIKDQRNYSAHPVVTYNGNTW
                     ELRDITKETCQDVIRKSYEIIFLKNPILGKKVTIEIIQYASRIHAMSVTPEEFHSALK
                     NSYLNKLSEKAKENLCKTAFKFVFQLSYGNEEADRDRESTFRLLNALIFDNKEFYLNI
                     LKKEIAKYRFTAESREEINKSLGENQQITYTKGFFLLTFIATHPELQHDFSDETIQNL
                     QISINDFKPKQQVLTEIEYYYRLRSLAVLGNNNEELQNHLNSLVDPILQQKMRVSSLP
                     SSTLETIYNQYLYFGEKEMFIDFMIEHLTDASSFRLADKDMEVLPWIYNKLNQEQFNK
                     LLYNLNGNNQFYKNSNFPPFISNLLDFYNQKFQVNLRKHYSGLLYPNAVTMDQGFQLK
                     DKELKKLYELAESKSDMYLDIIDNIINKSEDYLRKEINSEKELLNYVHKIK"
BASE COUNT          615 a          211 c          223 g          461 t
ORIGIN      
        1 agtttttatc agggaaatta tcgttctgca atagctgtca attacagtgc gcttatttta
       61 gatttaattg ataaattatc tgatttagca aatatttacg aggataatac ttctaagaaa
      121 attttagaag atatagctag actaagaaaa agtgatccaa actctccaaa atgggaaatg
      181 gaactactag aaaaagctta tagttcaact gagctaattg atagctatga atatgaggat
      241 ttaaaatata ttaaggatca aagaaattat tcagctcatc ctgtagtcac ttacaacggt
      301 aatacttggg aattaagaga tataacaaaa gaaacttgtc aggatgttat acggaagtcc
      361 tatgaaatta tattcctaaa aaatccaata ttaggaaaaa aagtaacgat cgaaattata
      421 caatatgcaa gtcgcataca tgctatgtct gttacacctg aagaatttca ctctgcacta
      481 aaaaatagct atctaaataa actaagcgaa aaagccaaag aaaacctatg taagacagcc
      541 tttaagtttg tttttcaatt atcttatgga aatgaggaag cagatagaga tagggaaagt
      601 actttcagac tacttaatgc cctaattttt gataataaag aattctattt aaatattcta
      661 aaaaaagaaa ttgcaaagta taggttcaca gctgaatcaa gagaggaaat taataaatca
      721 cttggtgaaa atcaacagat cacgtataca aaagggttct ttttacttac ttttatagct
      781 acccatccag aattacaaca tgatttttca gacgagacaa ttcaaaattt acaaatatca
      841 ataaatgatt ttaaaccgaa acaacaagta ctaacagaaa tagaatatta ctaccgttta
      901 cgttcccttg cagttctagg aaacaacaat gaagaattac aaaatcactt aaatagtcta
      961 gttgatccta tactccagca aaaaatgaga gtttcttcgc taccatcttc aacattagaa
     1021 acaatatata atcaatattt atattttggt gaaaaagaga tgttcataga ttttatgatc
     1081 gaacatctta ccgatgctag ttcattcagg ttagcagata aggatatgga agtattacca
     1141 tggatttaca ataaattaaa tcaggagcaa tttaacaaat tactatacaa cctaaatgga
     1201 aataatcaat tttacaaaaa cagtaatttt ccgcctttta tttctaatct gttagacttt
     1261 tataatcaga aattccaagt gaatttacgt aaacattata gtgggcttct atatccaaat
     1321 gcagtgacta tggatcaggg ttttcaatta aaggataaag aattaaaaaa actgtatgaa
     1381 ttagctgaat cgaaaagtga tatgtatcta gacataatag ataatattat taataagtct
     1441 gaagactatt taagaaaaga aatcaattcc gagaaagaat tgttaaatta tgttcacaaa
     1501 ataaaataat
//
LOCUS       DAFKHN010000200         1494 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.210, whole genome shotgun sequence.
ACCESSION   DAFKHN010000200 DAFKHN010000000
VERSION     DAFKHN010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.210"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            292..909
                     /locus_tag="LY912_002986"
     CDS             292..909
                     /locus_tag="LY912_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956585.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            950..1249
                     /locus_tag="LY912_002987"
     CDS             950..1249
                     /locus_tag="LY912_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBM6956586.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            1283..1450
                     /locus_tag="LY912_002988"
     CDS             1283..1450
                     /locus_tag="LY912_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBM6956587.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
BASE COUNT          523 a          223 c          310 g          438 t
ORIGIN      
        1 caaattctga tgtgaaaaat aaaatatacc atggaagaca taaaagaaaa actggataac
       61 tagtttattt aatggcagac cgttaaggcc tgccattttt atgtatttta gcggaataaa
      121 tataatcatg cgggagtgta aacttactgt ttcaaaaagt atactttttg acatgccttg
      181 attttctttg tttatgtatg gcataataac cacataatac aatttgaaac gtttctgatt
      241 taatctgatt gttttgaaac aattttagtg aaaaaagggt agataaaaac gatgagaaaa
      301 tttttttata tccgggtcag tagttatgat caatcgatcg aacgacaact gatttccgcg
      361 aaggaattag gaatccctga agaatatata tttgtagaaa aagccagcgg caaagatttt
      421 aaacgccctg aatatcaatt aatgaaacgg atgtttcgaa aaggagattt actctatcta
      481 caatcattag atagactagg cagaaataaa caaatgattt tagaagaatg gcgagaatta
      541 actaaggaaa agcagattga tatttctgtg ttagacatgc ctctgttaga tactgctagt
      601 tacaagcaac tagatgggtt agagacgctt atctctgact taattctgca attactcagc
      661 tatatggccg aagacgagcg gaaacgaatt aatagccggc aaagagaagg cgtagaagct
      721 gcgaaacaaa agggtgtaaa attcggcaga aagaaaattg ctttacctcc tgaatttcct
      781 gcgatctatt ctgactggaa agcaggaaag ataactgcag tctatgctat ggatcaattg
      841 ggcatgaaac gaaatacctt ttatcgacgg gtgaaagaat atgaacatac cttgcaccac
      901 ttttcttgat agatataaca gctattagac gggaagggag agtttgaaaa tggacttaac
      961 gaatcaaagg gtcgttttta ctggaacgct gcagcaaatg acacgaaccc aagccatcgg
     1021 tttggttcac tctttaaacg gccattgtca atcaagtgtt acttcaaaaa caaatttcct
     1081 ggtttgtggt cagtattcta agtcgttgtt tgatgattct ctctatacaa aaaaggaaca
     1141 aaccgcgcgg gacttgattg cgttaggtca tgagattacc attttatcag aagtcgaatt
     1201 ttatgcgtta attagtcaac agttgaaaga atggcaacgg tatttataat cgttagtaaa
     1261 atttacaagg aggaaaattt ttatgaagcg aaaatcttat gatcgttggg gcattgaaat
     1321 aactagtttt aatcgaaata ttgcttttca cgtggagtgt gactgtgggg aattagcaaa
     1381 aagtgtttat caaaaaaatt acttttactg tcctaaatgc catcgccgat acggggtaca
     1441 tggaacatag aaacgaaata gtgcggtaga aaagcgaatg aatgtagtat attt
//
LOCUS       DAFKHN010000201         1476 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFKHN010000201 DAFKHN010000000
VERSION     DAFKHN010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.211"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            72..557
                     /gene="vanZ"
                     /locus_tag="LY912_002989"
     CDS             72..557
                     /gene="vanZ"
                     /locus_tag="LY912_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBM6956588.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(844..1173)
                     /locus_tag="LY912_002990"
     CDS             complement(844..1173)
                     /locus_tag="LY912_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956589.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
BASE COUNT          509 a          223 c          222 g          522 t
ORIGIN      
        1 aaaacccacg ttaactagga cattgctata ctaatgatac aacttaaaca aaagaattag
       61 aggaaattat attgggaaaa atattatcta gaggattgct agctttatat ttagtgacac
      121 taatctggtt agtgttattc aaattacaat acaatatttt atcagtattt aattatcatc
      181 aaagaagtct taacttgact ccatttactg ctactgggaa tttcagagag atgatagata
      241 atgttataat ctttattcca tttggcttgc ttttgaatgt caattttaaa gaaatcggat
      301 ttttacctaa gtttgctttt gtactggttt taagtcttac ttttgaaata attcaattta
      361 tcttcgctat tggagcgaca gacataacag atgtaattac aaatactgtt ggaggctttc
      421 ttggactgaa attatatggt ttaagcaata agcatatgaa tcaaaaaaaa ttagacagag
      481 ttattatttt tgtaggtata cttttgctcg tattattgct cgtttaccgt acccatttaa
      541 gaataaatta cgtgtaagat gtctaaatca agcaatctga tctttcatac acataaagat
      601 attgaatgaa ttggattaga tggaaaacgg gatgtgggga aactcgcccg taggtgtgaa
      661 gtgaggggaa aaccggtgat aaagtaaaaa gcttacctaa cactatagta acaaagaaag
      721 cccaattatc aattttagtg ctgaggaatt ggtctcttta ataaatttcc ttaacgttgt
      781 aaatccgcat tttcctgacg gtacccccaa actaagattt catagataga ttttctgata
      841 actttaaaaa acacgaatag cggaaaggat gtcttcattc gctaaagagt aataaactac
      901 ttttccatct tgacgtgatt ttgccattcc atgttttttt aaaaaacgta aatggtgtga
      961 cgttgtagcg acactagcag taagtatttc tgctaaatca cagacgcaca tttccttata
     1021 ggtttctaaa gcatagaaaa ttttaattct agaaaaatcg ctgaaacatt tccctaacac
     1081 aagtaagttt gaaaaatctt tttgatccaa tttatttttt attccattta ctttttcttt
     1141 atgtacgaca gtcacttggc aaactttttt cattcatctc acctcacatt caaacgatta
     1201 tttgaatgaa gtatacctat ttgatcactc ttttgtcaat ctaccttaat tccaatacac
     1261 tattataagc aatttcatgt attgaagtaa acttacttgc aagtgcgttt ttgattccaa
     1321 gttaaaaaca tattattatt ctacataatt tcctaatcaa ataaaactcc tttgaaaatt
     1381 gttctaaagg agttttatta ttttgtattt ctactaaaaa tagcgtacaa tgtaattact
     1441 aagtaattac gaaatgtaaa ataatggagg aaataa
//
LOCUS       DAFKHN010000202         1438 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFKHN010000202 DAFKHN010000000
VERSION     DAFKHN010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.212"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            191..445
                     /locus_tag="LY912_002991"
     CDS             191..445
                     /locus_tag="LY912_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBM6956590.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="LY912_002992"
     CDS             446..763
                     /locus_tag="LY912_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBM6956591.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          515 a          207 c          281 g          435 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaagga
//
LOCUS       DAFKHN010000203         1421 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFKHN010000203 DAFKHN010000000
VERSION     DAFKHN010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.213"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="LY912_002993"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="LY912_002993"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBM6956592.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          496 a          184 c          236 g          505 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctattactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctggactaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatacta t
//
LOCUS       DAFKHN010000204         1407 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFKHN010000204 DAFKHN010000000
VERSION     DAFKHN010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.214"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            110..1282
                     /locus_tag="LY912_002994"
     CDS             110..1282
                     /locus_tag="LY912_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBM6956593.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          513 a          253 c          240 g          401 t
ORIGIN      
        1 tttttacaga taaagtccgt ataattgtgt aaaagtaaaa aggccatata acagtccttt
       61 tacggtacaa tgtttttaac gacaaaaaca tacccaggag gacttttaca tgacccaagt
      121 acattttaca ctgaaaagcg aagagattca aagcattatt gaatattctg taaaggatga
      181 cgtttctaaa aatattttaa caacggtatt taatcaacta atggaaaatc aacgaacaga
      241 atatattcaa gcaaaagaat atgaacgaac agaaaaccga caaagtcaac gaaatggcta
      301 ttatgagcgc agctttacga cacgtgtagg cacgctagaa ttaaaagtac ccagaacacg
      361 tgatggccat ttttcaccca cagtgtttga acgttatcaa cgaaacgaaa aagccctcat
      421 ggcttcaatg ttggaaatgt atgtatcagg cgtttcaact cgtaaagtat caaaaattgt
      481 ggaagaactt tgtggtaaat ccgtctctaa gtccttcgtt tctagcttaa cagaacagct
      541 agaacctatg gttaacgagt ggcagaatcg tttattatca gaaaaaaatt atccttactt
      601 aatgaccgat gtactctata taaaagtacg agaagaaaat cgagtactct caaaaagctg
      661 tcatatagcg attggaataa ccaaagatgg cgaccgtgaa attatcggct tcatgattca
      721 aagtggcgaa agcgaagaga cctggacaac attttttgaa tacctaaaag aacgcggttt
      781 acaaggtacg gaactcgtta tttctgatgc gcacaaagga ttagtctctg ccattagaaa
      841 atccttcacc aacgtaagtt ggcaaagatg ccaagttcac ttcctaagaa atatctttac
      901 caccattcct aaaaaaaatt caaaatcttt cagagaagct gttaaaggaa tttttaagtt
      961 cacagatatt aacttagcgc gtgaggctaa aaatcgattg attcatgatt atatcgatca
     1021 accaaaatat tcaaaagctt gcgcatcatt ggatgatgga ttcgaagacg cctttcaata
     1081 taccgtacaa ggaaattccc acaatcgact aaagagtacc aatctaattg aacgactgaa
     1141 tcaagaagta cgcagaagag aaaagattat tcgcatcttc cccaatcaaa catcagccaa
     1201 tcgcttaatt ggagccgttc ttatggacct acatgatgaa tggatttatt cttcaagaaa
     1261 atacatcaat tttgataagt agaaatggta aaaacattgt atagcatttt acacaggagt
     1321 ctggacttga ctcacttcct ttattatttt tcattttttt aaactattta atactaatgt
     1381 cttttataat agcttttcat atattat
//
LOCUS       DAFKHN010000205         1403 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFKHN010000205 DAFKHN010000000
VERSION     DAFKHN010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.215"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            19..351
                     /locus_tag="LY912_002995"
     CDS             19..351
                     /locus_tag="LY912_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBM6956594.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            967..1308
                     /locus_tag="LY912_002996"
     CDS             967..1308
                     /locus_tag="LY912_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBM6956595.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          499 a          182 c          317 g          405 t
ORIGIN      
        1 aattgggtgg tttattttat gtcatataca ggaattttga gtctcaaaga tatttgtcac
       61 tacggtaaac ggtgtaccgc tacagagaaa atcacgaaga aactatcaac tggccaaagt
      121 aaaaccgttg tgcagtgtaa gaaatatata atccagaaag acaaagtctc agaggaaatg
      181 atttattaca ttgggaaaca aaagcaaata attttaaaag atcctatccc cttaaaagag
      241 ctatatccaa caatcaaaca tgtttatgac caaaacggtg tactgattgg tcgaagaaaa
      301 aatggagtct tgcgttgtac cgcaaaaggg atggggcgtt tgatcggctg aattgatcat
      361 tctcataact tgtattttat cgtttttcgc ttgcttgaaa atattgtcga gacttctaaa
      421 ggaacttaga gtcactagaa aaataaggag tagacttgat ctatcaacaa ttcccttcgg
      481 ggagtgacgg ggtaggtttt aacgattggt aacgtaaaaa attggtcaat cgagtaaatg
      541 cgcttgtttg gatagtggtg aaatgaattt gtgtaaataa taagcgcaga gtaaacaaga
      601 gggaatttag aagttagaca agttagaata gcgtctagat taatcatgag cagctactaa
      661 gggatctaga ctttgacgca aactcatgga ataaggagta ggtcttctcg taatggggag
      721 gacgcacaag aaattgtgtc gtgtgctgca gtacatgtag atacttgcga ggacgttgat
      781 tattggatca atcgagcatt taccgctgtc tagggtttct cgtttcggac gccataaacg
      841 agtcgaaatt ttttatgtat ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct
      901 gaataaagtg aaaaaattaa tataaagcat agagaaaatg aaatttacgt aatggaggaa
      961 tgacaaatga aaaattatga tccgaatata cgattgggca cacatactat taaggtttct
     1021 ttccaacgtt gggattacaa aggatttgtg acgtttagaa ggggcggaaa ttgtaaagga
     1081 ttagatgttt tagcattaga cgaggatgat ttatacgatc aaacattgac tgataatcca
     1141 attggattcg gcttgctacc tgaagatgat gaaggtaatg aatggtttaa aatgacgctt
     1201 atgaatgata atggagacga attatctgtt gaagatactt ggtcatattt gagtgattat
     1261 attgtcagct ttgaaatcat tgaatttgta gcggataaag aagaataaaa actggaggaa
     1321 taaattttac agataaaggc ttagaaggag tcacgacgat taataaaaag gtagtattac
     1381 cttaggcatt gagtaaggaa ttt
//
LOCUS       DAFKHN010000206         1379 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFKHN010000206 DAFKHN010000000
VERSION     DAFKHN010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.216"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            102..1271
                     /locus_tag="LY912_002997"
     CDS             102..1271
                     /locus_tag="LY912_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBM6956596.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          506 a          201 c          220 g          452 t
ORIGIN      
        1 taaaatattt tgtgtaaata gatatttagg gtagaaaaaa agaaagtcca ttctgtaaaa
       61 ttaaagttac cacaaccgaa attttatagg aggactttct catgcccaat tttactacag
      121 aaattatgga aacactaatc aataaaggtg atttagatga attatttcga tgtcatttag
      181 aattagctgt taattcatta ttgcaggctg aattaacagc ttttcttgat tatgaaaaat
      241 atgatcgtgc tgggttcaat tcaggtaatt cccgtaatgg gaattattca cgttcattca
      301 gaacagagta tggagaatta aatttggtaa ttcctagaga tagaaatggt aagttttctc
      361 aacaaacttt acctgcttat aaaagaacca atgactcttt agaaaccact attattcagc
      421 tatttcaaaa aggaattact atgtctgaaa tctctgaatt gattgaaaaa atgtacgggc
      481 atcactatac gccacaaacc atttcaaata tgactaaaat agtttctgaa gatattattg
      541 cctttaaaga aaggtcctta gaatccagat actctgtcat ttttatggat gctactcaca
      601 ttcctttaaa aagacaaact gtttcaaaag aagcagttta tattgtaatt ggcattcgat
      661 tagatggaac caaagaggtt cttgggttta gtcttgctcc aactgaatct gcttatgttt
      721 ggaaagagat tcttcaagac ctaaaagacc gtggtttaaa agaggtttta ttagtcgtaa
      781 ctgatggttt aagtggcatt aacgatagta ttcatagtgt ttatccaaat gctcaatttc
      841 aacaatgttg tgtccatata tctagaaata tcgctcataa ggttcgtgtt agtgatcgac
      901 aagaaatctg tagcgatttc aaattagttt atcaagcaag ttcaaaagaa gaagcaaata
      961 atcaaataag gtttatgata gataaatgga aaaagcagta tccacgagtg gttaaattgc
     1021 tcatgaatcc tgctatatta accttttata atttccctcc gtcaatcaga agaactattt
     1081 attcaactaa tttgattgaa ggttttaaca aacaattaaa gaaatatacc aaaagaaaag
     1141 agcaatttcc taatgaagaa tctctggaga gatttctagt atctcaattc aacaactata
     1201 atcaaaagtt tctatgccga gttcataaag gttttaaaga aatacatgat acattagaat
     1261 caatgtttta acttgatcaa cagaatgggc ttttccattt acacaaaatt attgacgctc
     1321 ccgacaaaat tatgatcttg cgtaaagtta taaaatatta ataaaaatat tttattaat
//
LOCUS       DAFKHN010000207         1362 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.217, whole genome shotgun sequence.
ACCESSION   DAFKHN010000207 DAFKHN010000000
VERSION     DAFKHN010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.217"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1111
                     /locus_tag="LY912_002998"
     CDS             <1..1111
                     /locus_tag="LY912_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBM6956597.1"
                     /translation="LFQDHLERAINSLLQAELTAFLDYEKYDRNGFNSGNSRNGNYSR
                     TFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLETTIIQLFQKGITMAEISKLIE
                     KMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVIFMDATHIPVKRQTVSKEAVY
                     ITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRGLEEVLLVVTDGLSCIEESIH
                     SVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLVYQANSKEEALDHIDFMTRKW
                     KKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEGFNKQLKRYTRRKEQFPNEES
                     LERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          472 a          229 c          227 g          434 t
ORIGIN      
        1 attatttcag gatcatttag agcgagcgat taattcactt ctacaagcag agctaactgc
       61 ttttttagat tacgaaaaat atgatcgaaa tggattcaat tcaggaaatt cccgtaacgg
      121 gaattattca cgtacattta aaacagaata tggcgagttg aatttaacta ttcctagaga
      181 tcggaatggc gaattttctc aacaaacact accagcatat aagcgaacca atgattcatt
      241 agaaacgacc attatccaat tatttcaaaa aggcattact atggctgaaa tctccaaatt
      301 aattgaaaaa atgtatggtc accactatac gccacaaaca atctccaaca tgagtaaatt
      361 ggtggctgaa gatgttttag cttttaaaga aagaacgtta gaagccaatt attccgttat
      421 atttatggat gcgacgcata tccctgtgaa gcgacagact gtttcgaagg aagcagtgta
      481 tattacgatt ggtattcgtt tggatggaac caaagaagtt cttgggttta ctattgcccc
      541 aactgagtct gcttatattt ggaaagaagt tcttcaagat cttagaaaac gtgggttaga
      601 agaagtttta ttagtagtga cagacggatt aagctgtatt gaagaaagta tccatagtgt
      661 gtatccgaat gcccaatttc aacaatgttg tgtgcatgta tctagaaata tcgctcataa
      721 agttcgtgtt cgaggtcgaa aagaaatttg tgaggatttc aaattggttt accaagcgaa
      781 ttcaaaagaa gaggcattgg atcacatcga ctttatgact aggaaatgga aaaagcagta
      841 tccaagagtc gtcaatttac tcttgaatcc tgccctatta accttttata atttccctca
      901 cgccatcaga cgaacaattt attcgacgaa cctgattgaa ggctttaata agcagctaaa
      961 acgatatact cgaagaaaag aacaattccc taatgaagaa tctctagaga gattcttcat
     1021 ttctcaattt aatcaatata accaaaaatt tttaggtaga attcacaagg gatttaaaga
     1081 aattcaggat acattagagt cgatgattta actgtaatta acagaatgga ttttccattt
     1141 acatataatt cttgacgcta ccataatcta aataaccatc atattcatct actacttata
     1201 taattgagtt ttattaaact ttttaagttt ctattctatc aaatatttaa acaatctctg
     1261 catccgaaaa gactacctcg tatagtttta ctaacaatat ttttattagc gtgttcaaat
     1321 cctgatttct tgtatcaatt attttctgtt cactttcaat aa
//
LOCUS       DAFKHN010000208         1356 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFKHN010000208 DAFKHN010000000
VERSION     DAFKHN010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.218"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            82..>1356
                     /locus_tag="LY912_002999"
     CDS             82..>1356
                     /locus_tag="LY912_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBM6956598.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLIN"
BASE COUNT          461 a          261 c          257 g          377 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaat
//
LOCUS       DAFKHN010000209         1302 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFKHN010000209 DAFKHN010000000
VERSION     DAFKHN010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.219"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            52..>1302
                     /locus_tag="LY912_003000"
     CDS             52..>1302
                     /locus_tag="LY912_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBM6956599.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          403 a          260 c          252 g          387 t
ORIGIN      
        1 cctgaaatcc tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat
       61 actcagctta tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat
      121 tgtttaacta aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg
      181 tacaagccag aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg
      241 gggacgacaa ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag
      301 ctgaagaaac aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct
      361 gttgctgaaa aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta
      421 aaagagaata cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc
      481 tatcgtgtca tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag
      541 gtcttatgct ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc
      601 atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat
      661 ttagaacgct atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt
      721 attgatatgt atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg
      781 atcatcgatc gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg
      841 aaagaaacca cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa
      901 ttgaagcgct attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg
      961 gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta
     1021 gctgcttgtc ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta
     1081 aagaaaagag atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca
     1141 gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg
     1201 cttcactaca gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta
     1261 aaacgcaatg cgtacggctt tcgcaacttt tacaatttca aa
//
LOCUS       DAFKHN010000210         1297 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFKHN010000210 DAFKHN010000000
VERSION     DAFKHN010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.220"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(7..441)
                     /locus_tag="LY912_003001"
     CDS             complement(7..441)
                     /locus_tag="LY912_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956600.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(458..>1297)
                     /locus_tag="LY912_003002"
     CDS             complement(458..>1297)
                     /locus_tag="LY912_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBM6956601.1"
                     /translation="SLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKI
                     DNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKN
                     YSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEI
                     GKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNY
                     ISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFN
                     NIS"
BASE COUNT          446 a          223 c          142 g          486 t
ORIGIN      
        1 gaataattaa ttgctttcac tcaaatactt ataatctatt aacttgtagt tgtttaactt
       61 ttctgaaaaa gttagaccca cgtaataatc ttcccagctt tctctttcaa ttaactgatc
      121 caatttttga taatccataa attcatcatg tatcaaaaag aataaataac ttgatatttt
      181 agcatctagc ttaatcagat taaataatgt ttgtttaaaa ttgctaccat taatatgact
      241 gatagattct ctagcttctt cacataaact ttttacttta ttaattacta ctttgtcata
      301 ttcatttaac acactattat taccattact tagacgctca gattctacga aacaactcaa
      361 atcagaaatt tcccaaaaaa attttttgtt aaaatccaat ttcctcaact cctccaaact
      421 acgtaaatga tatagtctca taataaaata aaacctctca gctaatgttg ttgaaattgt
      481 ccactaaacc taattgatat tgcttaggag atacacctgc gtactttttg aatactctcg
      541 aaaagtgtga agaatctgaa aatcctaaac ctaaagaaac ttcactgata gtatggtttg
      601 atttcaacat tattttagcc gtagaaattt ttcgcttaga gatataatta taaatcgtaa
      661 tatgcatttc attcttaaag ctttctctta atttagtttc acttacagaa aaataattag
      721 ctatttcctt tacagtaatt cttttataga tatttaagcc gatgaattga acgacagaag
      781 aaattaaggg agaaagatgc tctatcttag tttttccgat ttccttagta taataaacaa
      841 tcccagaatc cctcactttt aagacctcag gtaacgatac agctaattcg ttttcttgta
      901 tcaaagcatc tctactttga tacgcttcta ttatatccat tcctaatgtt atagacgttt
      961 gtgctaactt ttcaaaaaca atgatagaat aatttttttc agaccgaatc gtatctccac
     1021 taacacttgg aattattcca ttactcagat taaaaaccat gttttctaaa tttcgaatat
     1081 ctccattttt aacatattcc agtattttat tttcataaag aaacagatat atttctggat
     1141 cgtaattttg tgataacaga ttatctattt tgatttgctc gatagtttta cttagatttt
     1201 ctgtatattc aattaacggt tcatggaata gatcttctat ttttccagta aaaaaataat
     1261 gaactaaaat cagaatatct cgaatgtctc ctaaaga
//
LOCUS       DAFKHN010000211         1294 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.221, whole genome shotgun sequence.
ACCESSION   DAFKHN010000211 DAFKHN010000000
VERSION     DAFKHN010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.221"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(469..810)
                     /locus_tag="LY912_003003"
     CDS             complement(469..810)
                     /locus_tag="LY912_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBM6956602.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIEKLQRKV"
     gene            complement(800..1081)
                     /locus_tag="LY912_003004"
     CDS             complement(800..1081)
                     /locus_tag="LY912_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBM6956603.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
BASE COUNT          366 a          267 c          158 g          503 t
ORIGIN      
        1 ctcacccacc gcaagcggtt ggttgagttg tggctcctat tcaaaattca ctaatctgtt
       61 attttttatt tctattcaaa taggtaacgt tcgtttgcaa gcaaactctc tctatgtaac
      121 ttgccagtta catcagcggt aacgctacgt cgcaagcgac ttgctctaat gaaactgccg
      181 tttcattctg cctgttcgtt cgtagcaagc tacttcactc accgtatccg tctgaattat
      241 tgttatttat tgctattcaa tatccgtcag acattttatt tatttacata cattttatat
      301 aaaatatata ttataattcg tatattacta aatatcatta tttaacaatt cttaacgttt
      361 tattaatgtt tataaccacg tatatattta cgtatatttt catatacata aatacgttta
      421 tataaacgta tatcttaata tacatataaa caaaaaagaa aagccttgtt agacttttct
      481 ttgtaatttc tcgataaacc tatttagctt tttcgtatca ctagctgata acataccaac
      541 ctttttgaat gatatgttct ctcggctttt gggaatagcc tttaaagacc ctacgtcaat
      601 ccatgattgc tttttaagtc ctgctttttc ccattctgca ataggaaaat acaccctctt
      661 tatttggtct gattttttct catattgact tgtgattcca aagaattcta ctctatcttc
      721 tttatcacta accaccaaaa taggtcttct tttaccacca tttttatctg taaatgcaac
      781 atataccgtt actatctcat taggcttcat cgaaccactc ttctaacttt tcatctgtat
      841 ctagaacatc tactggcatg tccttagtta gctgttgcaa tctgattcct tgcttctcct
      901 cttcacttag ctttatctct actggaaact cacctctagc gactacttgt ttgtaaagaa
      961 ttgttattgc tgttgtagga tttaaaccta gctcttccaa tatcatttct gcgttctctt
     1021 ttaaattctt gtctattccg acttggattc tgcttttttc agttggattt ttgaccttca
     1081 tttcatccac tccttttgag tataaaacac tcattattta tcaaattgtc cacatttatg
     1141 attatattat actcttaata aactacattg caagtaatct aatcaaatta agatgctata
     1201 tcatacggta attgaacaaa ttgtcgctaa cccacacata cggaatcgta atgaatgaaa
     1261 aaaagacaag cctattcgca gtaggcttgt cttt
//
LOCUS       DAFKHN010000212         1246 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFKHN010000212 DAFKHN010000000
VERSION     DAFKHN010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.223"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            200..742
                     /locus_tag="LY912_003005"
     CDS             200..742
                     /locus_tag="LY912_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956604.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="LY912_003006"
     CDS             898..>1246
                     /locus_tag="LY912_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBM6956605.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAFKHN010000213         1239 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.224, whole genome shotgun sequence.
ACCESSION   DAFKHN010000213 DAFKHN010000000
VERSION     DAFKHN010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.224"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(241..1101)
                     /locus_tag="LY912_003007"
     CDS             complement(241..1101)
                     /locus_tag="LY912_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956606.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT          373 a          237 c          179 g          450 t
ORIGIN      
        1 aacaaacaac acatttttgt gtgttgctta tttccctcta actatcgttt tctatttgat
       61 ggttaaccta cttaaaataa atactgcaac gacaaacgga gatcaagcat gctttgtaac
      121 gtattttacg ataattacga ctttatttta ttactctatc ttgctgccat acccgtctat
      181 ccctaatcat ctttggtgaa ttttttcaaa gttagcataa caaaaataag tattttttcc
      241 ttagttaatc aatagtatca tttttttcat atgatttaat tcatcaatta attttttgtt
      301 tttattaatt ttagcaaaag ctagtgcatc ttgaatcaat tcgagcactt ctgccttcga
      361 cttattttta gcctgtgcgt tcttcgctaa ttgggcagca gctcgtgcta agtaataagt
      421 caaatggtta tccgaacaaa tatcgattgc gtaatttagt agtgcatcac ttgtttccaa
      481 atcaccgtct tgcgcaaaaa aaacaccaca atgaaagacg atatttaaca cccgccagat
      541 atcttctgtt gtacgaatcg gatacgtata aattttttca aacactcgat tgaaataaac
      601 ttctgctttt tccaactctt tttctctagc atagaccatt ccaatacctg tatatgccaa
      661 taaacgaaac aacgtgttgg ctgtttctgc catcaacaac tgatcaaaat ggaacaacac
      721 atccgtaatt ggtgcattcg taaaaatcat ttcaaatcct tttagatagt agtaacgtgc
      781 aatcagctca gactcgtcaa ttaccttggg atcaatggct gctaaaatct gtgtcaattg
      841 ttcatattca ctcgtaatca gtgaaaactc tgctttttct agctgttcat caagttgtgt
      901 attgatcacg ttcatcgaag aaaaaagttc aactaacgga agattgattc gattacataa
      961 tttgattaaa atttttaacg aagggacttg accattgttc tcaaatttac ttaatgttgc
     1021 ttgtgtacaa attccttcag acacttcttt ttgagataag ttggcagcct ttcttgccgt
     1081 aataaatttt tcaatgttca ttattttctc tccaatcaga cctcacacga aaatcatttc
     1141 tgtctcgatt ttagcatgtt ttctttggga atgctttagg ttctgttgca aagttttaaa
     1201 taaagaataa agtcccttac ggtatctatg atttaagct
//
LOCUS       DAFKHN010000214         1215 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.225, whole genome shotgun sequence.
ACCESSION   DAFKHN010000214 DAFKHN010000000
VERSION     DAFKHN010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.225"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            2..>1215
                     /locus_tag="LY912_003008"
     rRNA            2..>1215
                     /locus_tag="LY912_003008"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          368 a          242 c          352 g          253 t
ORIGIN      
        1 ataagggcgc acggtggatg ccttggcact aggagccgat gaaggacggg actaacaccg
       61 atatgctttg gggagctgta cgtaagctat gatccagaga tttccgaatg ggggaaccca
      121 acatctttaa taggatgtta cgattgtgtg aatacatagc acattcgagg tagacgcaga
      181 gaactgaaac atctaagtac ctgcaggaag agaaagaaaa ttcgattccc tgagtagcgg
      241 cgagcgaaac gggaaaagcc caaaccagca agcttgcttg ttggggttgt aggactccaa
      301 tatggtagtt ctttcagata gtcgaatgac ttggaaaagt cagtcaaaga gggtaaaaac
      361 cccgtagacg aaatgtggaa gacacctagg aggatcctga gtacggcgga acacgagaaa
      421 ttccgtcgga atccgggagg accatctccc aaggctaaat actccctagt gaccgatagt
      481 gaaccagtac cgtgagggaa aggtgaaaag caccccggaa ggggagtgaa atagaacctg
      541 aaaccgtgtg cctacaacaa gtcaaagccc gttaatgggt gatggcgtgc cttttgtaga
      601 atgaaccggc gagttacgat tgcatgcgag gttaagttga agagacggag ccgcagcgaa
      661 agcgagtctg aatagggcgt ttgagtatgt agtcgtagac ccgaaaccat gtgatctacc
      721 catgtccagg ttgaaggtgc ggtaaaacgc actggaggac cgaacccacg tacgttgaaa
      781 agtgcgggga tgaggtgtgg gtagcggaga aattccaaac gaacttggag atagctggtt
      841 ctctccgaaa tagctttagg gctagcctcg gaattgagaa tgatggaggt agagcactgt
      901 ttggactagg ggcccatctc gggttaccga attcagataa actccgaatg ccattcattc
      961 atatccggga gtcagactgt gagtgataag atccatagtc gaaagggaaa cagcccagac
     1021 caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg atgtggggtt gcacagacaa
     1081 ctaggatgtt ggcttagaag cagccaccat ttaaagagtg cgtaatagct cactagtcga
     1141 gtgaccctgc gccgaaaatg taccggggct aaacatatta ccgaagctgt ggagtacacc
     1201 tttaggtgta ttggt
//
LOCUS       DAFKHN010000215         1204 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.226, whole genome shotgun sequence.
ACCESSION   DAFKHN010000215 DAFKHN010000000
VERSION     DAFKHN010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.226"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..455)
                     /locus_tag="LY912_003009"
     CDS             complement(<1..455)
                     /locus_tag="LY912_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956607.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRA"
     gene            563..847
                     /locus_tag="LY912_003010"
                     /pseudo
     CDS             563..847
                     /locus_tag="LY912_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
BASE COUNT          372 a          181 c          219 g          432 t
ORIGIN      
        1 gctctggatt taaaggcatt tacttcttca gtcagaactt tagtcatgtt ggacatggtt
       61 tgtggagtat agtgatgacc gtacattttt tcgatcaaat cagcaatttc agacatcgta
      121 acaccttttt cgaataaatg gataatagtg gtttccaatg tatcgtttgt tcttttgtag
      181 gctggtaaag tttgttgttt aaactcacca ttacgatctc taggtatttc caatgttaat
      241 tcaccatatt cggttttgat tgatcgaaag taagaaccgt ttctcgaatt acctgaatta
      301 aaaccagtgc gatcatattt ttcgtaatct aaaaaagccg ttaattcagt ccgtaggagt
      361 gtgtttatcg ctttttctaa gtgcgaacgg aataattcat ttaaatcgcc tttagtgact
      421 agagtttgca caatttctgt agtaaaatca ttcataggga agtcctcttt tctgtgaatt
      481 ggttgtcgtt aactttattc tacagaaggg acttcctttt ttgtatggat tttttcattt
      541 acacaaaata ttttatactc tcattttaat acaagatgat ttacaccata cgcatcggtt
      601 atggttaatg aataaaatta atctgtattt tgggcattct tatgtttttg ctttttatga
      661 ttacaggaca aatataactg aagtagattt ggttatttct aattactaca tcgacactgg
      721 aaaaacgcca ttactgttaa tgaaaaatat acctaccgaa agaaactggc gtttgttcga
      781 gaaaacgatt tatcaattga aaaaagaaaa agaggttgtg aaatcagcgt tttgtcctga
      841 gtattagaga aacaaacgga aaaatagttt ttcatatttt gccgtttttg agctaatacc
      901 gagggacagc tgattgaaca ccatttattg agagattgtg aaaaaactgt cctgcatcaa
      961 gtaataagaa cagccaagta aaaacagctt ctcatgtttg ttgaatattg tgacttgtga
     1021 ccgaggagtt ggcaagagaa caccgtttat tcggaaaaag ggactgtgac actacatgtc
     1081 acagtccctt tttgattgaa ttatctcatt tgttttctaa ttttttcttt atttgagaaa
     1141 atagttgaac tggataaaaa gtactggacg tgtcaaaatt attttggatc aaattagatc
     1201 tatt
//
LOCUS       DAFKHN010000216         1203 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.227, whole genome shotgun sequence.
ACCESSION   DAFKHN010000216 DAFKHN010000000
VERSION     DAFKHN010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.227"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(73..984)
                     /locus_tag="LY912_003011"
     CDS             complement(73..984)
                     /locus_tag="LY912_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBM6956608.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          350 a          250 c          173 g          430 t
ORIGIN      
        1 agctaacgtt accccaaaag tgctagtaca ataatgctgt tcattaattt cgttggtttc
       61 attccgccat ccttacctcc ttgaattagt atgtgttgat ccgggaaaca ctgtcacaat
      121 tacaccgtct atattgtttc ctgatatctc ataacgaaga ttagtcggca catgaatggt
      181 ggtattttta gtaacaggat aataaaagat ctcatatttt tccccattta cactaacaga
      241 aatggttttt tcttctttta ggtaatccat atattcctcg agaacgaaat tcttttcttt
      301 cataatcgca ctatgtggta aaccaacata gcgaatatgc catggttcat attgaattcc
      361 tgttaactct gttttgtcct ctggataacg taaaatgaac ccgtatttcc aagcattttc
      421 ttctatccac tttccttcag gggctcgttc cattttcgtc aagcttgatc ctacatctag
      481 tgataaacct gaattatgct cactataacc tgctggtaag gcatactcag cccccatttc
      541 ttggtaaagc acactttgct catcaaagtc tcgatagcca ctattaataa taaaatgact
      601 aacgccaccc tttacagcat cattgaccat ctctgaaaat ttttgtgcta tttcttttga
      661 catataaata ttactatcaa gcaacccgta tccatttatt aattcgtcat gtttagataa
      721 attcacgata tctgacttca cactttcttg gcgaacagga tatttactat tgattaatag
      781 cagatttcct tgataaacct gttcttctgt aattgttttc tcttgggtat tttcagaagt
      841 cccactattt tctaaatgtt ctttgggatt ttgatcataa ttttgaaatt cgactttttc
      901 ctgagaaaac agtgcttcat taacgtagtc ataacctaag tatattaaga ataacaataa
      961 caataaaaaa aacaacttct tcattttcag tctcctcctt aactatatag ttggaagtat
     1021 gaaatatttc tagaatcttc cccttaaacg gcacaatctc gtttgagatt gtgccgtttt
     1081 gccccgtaaa ttacagtcaa ttatttcgcc ctactggatt tactattatc accaatgtag
     1141 atgaattttc ataagtgata cccatgctga atttaacgag gctgaactgc ctgttgacaa
     1201 tgg
//
LOCUS       DAFKHN010000217         1164 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFKHN010000217 DAFKHN010000000
VERSION     DAFKHN010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.228"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            66..800
                     /locus_tag="LY912_003012"
     CDS             66..800
                     /locus_tag="LY912_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HBM6956609.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          431 a          184 c          179 g          370 t
ORIGIN      
        1 aaataagtgg ttataatgga ttgttaatat aaacattcat tataacctca taggagtggg
       61 ttataatgaa caaaaaaaat ataaaagata gtcaaaactt tattacttca aagcatcata
      121 taaatgaaat tttgagaaat gtacatttaa atacaaatga taatattatt gagattggtt
      181 cagggaaagg tcatttcacg tttgaattag ctaaaaggtg taattatgta accgccattg
      241 aaatagatcc taaattatgt aggataacta aaaacaaact tattgaatat gagaacttcc
      301 aggttatcaa taaagatatt ttacaattta agtttcctaa aaataagtca tataagatat
      361 atggaaatat accctacaat ataagtacag atataattcg aaaaattgtt tttgaaagca
      421 cagctacaga aagttattta atagtggaat atggatttgc taaaaggttg ctaaatacaa
      481 atcgttcact agcactattt ttaatgacag aagttgatat atccatatta agtaaaatcc
      541 ctagagaata ctttcatcca aaacctagag ttaatagctc gttaattgta ttaaaaagac
      601 acccttcaaa aatatcactc aaagatagaa aacaatatga aaattttgtt atgaaatggg
      661 ttaacaaaga atacataaaa ctattttcca aaaaccaatt ttatcaagcc ttaaaatatg
      721 caagaattga cgatttaaac aatattagct ttgaacaatt cttgtctctt ttcaatagct
      781 ataaattatt taatagataa gttaaggggt gcataaactg catcccttaa cttatcttat
      841 tttgcttaaa caatcttggc ccgtaaactg cataactcat atgtaaatcg ctccttttta
      901 ggtggcacaa atgtgaggca ttttcactat ttccggcaat tacttccatg taaagtataa
      961 cccactatac tttgcaagca aagtgtgggc tcgccgaggg gtcttgcaga cggctctttc
     1021 ggctcttttg agccgagtat cagcgcaccc ttatggtgca attagctgat acctgtttga
     1081 cgatttgctg ccctaccttt tcggtaggta tgcaaacctc aaaccaaaat aaaaaccccc
     1141 ttcgacttcg tcagggggtt ttta
//
LOCUS       DAFKHN010000218         1158 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.229, whole genome shotgun sequence.
ACCESSION   DAFKHN010000218 DAFKHN010000000
VERSION     DAFKHN010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.229"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..>1158
                     /locus_tag="LY912_003013"
     CDS             <1..>1158
                     /locus_tag="LY912_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="HBM6956610.1"
                     /translation="DQHLSFSINSLGTEEWDNSFGKVYSGLIEAGLPSIMAGHIHMPA
                     YSKHFNPDLKDEDLLPATLSKELITDLLRGKLGFNGLVVTDASHMLGMTGAMKRSELL
                     PTSIAAGCDLFLFFNDPDEDFNYMMEGYRKGIITDDRLLDALKRILGLKAKLGLHKKA
                     KEQILLPKQEALEKIGLIENKSIFKEVADQAITLVKDKQDIWPIVPEKYKRILLVDVH
                     GVKGGFGEVVAGNRPQAIDLLKQILSAKGFEVEKYISPEEELKGLSQEEKIKNIAGIY
                     AAKRPIKNLTKKYDLIINIANVNPGTVQRIVWPASKGTPDIPFYIHEIPTIFVSVQCP
                     FHLADVPQVKTYINTYDGKQETLEILVDKLMGLSEFKGVSPIDAYCGLKDT"
BASE COUNT          426 a          151 c          220 g          361 t
ORIGIN      
        1 agatcagcat ctatctttta gtattaatag tttaggtacg gaagaatggg ataattcttt
       61 tggaaaagta tactcaggct taatagaagc tggattacct tcaattatgg caggtcatat
      121 ccatatgcca gcttattcaa aacattttaa tcctgatctg aaagatgaag atttacttcc
      181 tgcaacttta tcaaaagaat taatcactga cttacttaga ggaaaactcg gatttaatgg
      241 attagtagtt actgatgcta gtcatatgtt aggaatgact ggggcaatga aacgatcaga
      301 attattgccc acttctattg cagctggatg tgatctattt ctatttttta atgatccaga
      361 tgaagacttt aattatatga tggaaggcta tcgtaaagga attatcactg atgatcggtt
      421 attagatgcc ttaaaaagaa ttttagggtt aaaagctaaa ttgggattac acaaaaaagc
      481 aaaagaacaa attttattac ctaagcaaga agctctggaa aaaattggtt taattgaaaa
      541 taaatcaatt tttaaagagg tggctgacca agcaattaca ttagttaaag ataaacaaga
      601 tatttggcct attgtaccag aaaaatataa aaggatttta ctagtagatg tacatggggt
      661 aaaaggtggg tttggtgaag tagttgctgg aaatagacct caagccattg atttattgaa
      721 acagattttg tcagcaaaag gatttgaagt tgaaaaatac atttcacctg aagaagaatt
      781 gaaaggatta tcgcaagaag aaaaaattaa aaatatagct ggaatatatg ctgctaagag
      841 accaattaaa aatttaacta aaaaatatga cttgatcatt aatatagcta atgttaatcc
      901 aggcacagtt caacgaattg tctggccagc aagtaaagga actccggata taccgtttta
      961 cattcatgaa attccaacaa tttttgtatc tgtacagtgt ccgtttcatt tggctgatgt
     1021 acctcaagta aagacttata ttaatactta tgatggaaaa caagaaactt tagaaatatt
     1081 ggtggacaaa ctaatgggtc tttctgaatt taagggagta agtccaatag atgcttattg
     1141 tggtttaaag gatacatt
//
LOCUS       DAFKHN010000219         1145 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFKHN010000219 DAFKHN010000000
VERSION     DAFKHN010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.230"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            66..467
                     /locus_tag="LY912_003014"
     CDS             66..467
                     /locus_tag="LY912_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBM6956611.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            461..706
                     /locus_tag="LY912_003015"
     CDS             461..706
                     /locus_tag="LY912_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6956612.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            1060..>1145
                     /locus_tag="LY912_003016"
     CDS             1060..>1145
                     /locus_tag="LY912_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBM6956613.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKE"
BASE COUNT          431 a          154 c          209 g          351 t
ORIGIN      
        1 tttcgaaaaa aaggggcttt ctgattgttg tattagtgga aagggggaaa aaggagcata
       61 ttatcatgca acaacattac aatgacatat ctatacaaca ccaatttgat gcctactgta
      121 aaaaagtatt acgaaacgaa gctaagtcta ttcgaaaacg aaacgctaac ataaaggata
      181 atgaggaacc attggcagat tcaaatgaag gcaggtattc ccaaactcat tttgatgaac
      241 aagatgtcta tttcttattt ggaatggaaa tattaatttc agatcaaaag ttatcagcag
      301 caattgatca gttatcggag ataagaagaa agattatcct actttattat tttgcaggtt
      361 ttaatgatgc tgaaatcggt aaaattctca atatgagcac aagtggtatc tggtatcaac
      421 gaaagaaggc agttgaacaa ttgaaaatgg ggtatgacct atggtagata aatctaaaaa
      481 gcggcagtac ctattagttc cactatccat tatcttatct gctctagaag gagatccaat
      541 ttcgatcaag atgatactca aacattatca ttcttatatg gctaagttat gtttgacaaa
      601 tggatttaac gaggtaggtc aattcgttac ctatgtagat gaatatatga taagtcagct
      661 agaaattaaa ttaatagaag cgatcttaaa atttaaaatt aactaattaa aaaaatcccc
      721 tttccacttt ttctgtttaa aagaatcttc taatagttaa ggaattagta gattctttta
      781 ggtagaaaac ctattgttca ttgaaaatta aatagattct atcagtacgt taacacttta
      841 aggagcatat tttagttgcg ccatgatttc ttgctgtaaa gaaggagcga taaatattct
      901 aaaataattt ttatagtcaa taaaaagcga tgatttaaag ttgggataat gatacttccg
      961 taaggctcgc cgtaaacttg gggagaggtg aaattcctat gtgcttttga caaaagcagc
     1021 tgatagaaat aaatgaaaaa aagtaaggaa ggtgctataa tgaaaacagc tactcgaaaa
     1081 gatttgatta atctaggttt ttctcagtac tatgctaata aaatcttcaa ggaatgtaaa
     1141 gaaaa
//
LOCUS       DAFKHN010000220         1133 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.231, whole genome shotgun sequence.
ACCESSION   DAFKHN010000220 DAFKHN010000000
VERSION     DAFKHN010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.231"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..434)
                     /locus_tag="LY912_003017"
     CDS             complement(<1..434)
                     /locus_tag="LY912_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBM6956614.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVD"
     gene            785..1084
                     /locus_tag="LY912_003018"
     CDS             785..1084
                     /locus_tag="LY912_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBM6956615.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT          415 a          163 c          185 g          370 t
ORIGIN      
        1 cagtctacaa aatctgcgct tgataagaca gagtgctcaa aggtactttc ttttatgttt
       61 gaaccagata aatttacata gtccatttta caattctcga ataacgtgtt cccaatataa
      121 ctttccatca atttagtacc tgttaattta caattgacaa atttcacgcg atgcaacatg
      181 ctttttgtca atatacagcc tgaaaaatca cagttttcga atatacagtc ggtaatctcc
      241 attctttgaa aatcattgga agcaaaaaat gcatacttga aaatagattt gtaaataatt
      301 ggatggcaga ttatttggtt ttcgatgacc tctttttgtg aaaggatatt atacagttca
      361 aaatcttcgt tttcatagat atgaaaaaag gatcctttat tcaagcttgc ttcattaact
      421 ttaggaaaaa tcatatttaa ttacctccat tttcataaag tcatattaac aaaagctaaa
      481 ccaacttaca ttagcagaaa atgagatagg ttttcgcctt tttcgataac gatagtgtcg
      541 ctatctcttg aaacgttctt agaattgccc tgagagacac aaattaggcg taattctaat
      601 aaaaatctta gaataaaaat ttttactgat ttaatttaga atgtttttaa aataaaaatc
      661 gttgccataa cagtgtattg aaaggtttta acaatccagt aatgatttaa aaaaatctag
      721 atgtagcgta tactttgttt atagaatgta gtgggaagaa atatattttt gggaggaaat
      781 cgtgatgtct aaaagtgaag aaatagaaaa catggtacta aaattatatg atctcgtttt
      841 aaatccagag atcaaagaaa aggaacgtat acttttgata gacgcaaaga caggcttaga
      901 aaaaggtcag tattatccta aagtcataaa taatttggaa cgtagtttac gtccgttagc
      961 aatcagggga gaattgtcta aaccagtatc accgttttat atggagatat caacaatagg
     1021 aaaatttgaa aaagaattag gtcgaggaat ggcttcggca ccgattactt ttgggcattt
     1081 ataaaaacga gttattcatc tcaatgaatt aaaaagtata gtcaatctca taa
//
LOCUS       DAFKHN010000221         1109 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.232, whole genome shotgun sequence.
ACCESSION   DAFKHN010000221 DAFKHN010000000
VERSION     DAFKHN010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.232"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            244..>1109
                     /locus_tag="LY912_003019"
     CDS             244..>1109
                     /locus_tag="LY912_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBM6956616.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQGFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHKKLNL"
BASE COUNT          421 a          132 c          221 g          335 t
ORIGIN      
        1 ataaaaaaag cacctgaaaa ggtgtctttt tttgatggtt ttgaacttgt tctttcttat
       61 cttgatacat atagaaataa cgtcattttt attttagttg ctgaaaggtg cgttgaagtg
      121 ttggtatgta tgtgttttaa agtattgaaa acccttaaaa ttggttgcac agaaaaaccc
      181 catctgttaa agttataagt gaccaaacaa ataactaaat agatgggggt ttcttttaat
      241 attatgtgtc ctaatagtag catttattca gatgaaaaat caagggtttt agtggacaag
      301 acaaaaagtg gaaaagtgag accatggaga gaaaagaaaa tcgctaatgt tgattacttt
      361 gaacttctgc atattcttga atttaaaaag gctgaaagag taaaagattg tgctgaaata
      421 ttagagtata aacaaaatcg tgaaacaggc gaaagaaagt tgtatcgagt gtggttttgt
      481 aaatccaggc tttgtccaat gtgcaactgg aggagagcaa tgaaacatgg cattcagtca
      541 caaaaggttg ttgctgaagt tattaaacaa aagccaacag ttcgttggtt gtttctcaca
      601 ttaacagtta aaaatgttta tgatggcgaa gaattaaata agagtttgtc agatatggct
      661 caaggatttc gccgaatgat gcaatataaa aaaattaata aaaatcttgt tggttttatg
      721 cgtgcaacgg aagtgacaat aaataataaa gataattctt ataatcagca catgcatgta
      781 ttggtatgtg tggaaccaac ttattttaag aatacagaaa actacgtgaa tcaaaaacaa
      841 tggattcaat tttggaaaaa ggcaatgaaa ttagactatg atccaaatgt aaaagttcaa
      901 atgattcgac cgaaaaataa atataaatcg gatatacaat cggcaattga cgaaactgca
      961 aaatatcctg taaaggatac ggattttatg accgatgatg aagaaaagaa tttgaaacgt
     1021 ttgtctgatt tggaggaagg tttacaccgt aaaaggttaa tctcctatgg tggtttgtta
     1081 aaagaaatac ataaaaaatt aaaccttga
//
LOCUS       DAFKHN010000222         1032 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.233, whole genome shotgun sequence.
ACCESSION   DAFKHN010000222 DAFKHN010000000
VERSION     DAFKHN010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.233"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1001
                     /locus_tag="LY912_003020"
     CDS             <1..1001
                     /locus_tag="LY912_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBM6956617.1"
                     /translation="YIVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRT
                     LASLIPMTKVKRNWLPRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKAL
                     VSYFMQFERRARLKVKVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIR
                     VRIMKSFDRNDPTQAKYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVD
                     RLLSISDELRIAYFYYQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYES
                     GIRLALELPYSNAKIENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          328 a          207 c          193 g          304 t
ORIGIN      
        1 cctacattgt cgatagaaac tgctttatcg ctaaacaagt gcgctataaa attttagaag
       61 agctaactga aaaacaagca atgacgacaa ttgctaagca ttgcggcgtt tcttggtcga
      121 ccgtttctcg gacactcgct tctctgatcc ccatgacaaa agtaaaaaga aattggttac
      181 cgcgttgttt attaatggat gaatttcgtt cactgaaaaa tcaagtcggt ccctactcct
      241 tttcttgtat ggatggcgat actggaaaat tactggatat tcttccttca cggaagaaaa
      301 aggctctcgt ttcttatttt atgcaatttg aacgacgcgc acgattgaag gtaaaggtca
      361 tcgtgacgga catgaatgtt tcttatgcct ctctgataaa ggaatgtttt ccaaaggcaa
      421 aactcgttgt ggatcgtttt cacattgtca aacatctcat tcgtaaattt gaggatattc
      481 gcgtacgaat catgaaaagc tttgatcgaa acgatccaac acaagccaaa tattatcgac
      541 aattaaaggc gttgtctcgg cttctgatca aacgacagga caagcttgtt tatgacaaat
      601 ggaccaaatg gcgcaatttt ggttgggcgt atctcaccga aagtgaagtg gtggatcgtc
      661 tgctttcgat ctctgacgaa ttacgaatcg cctattttta ctatcaagaa attcttcaag
      721 cgtttcacga caaagaggcg gacactttct ttaaacttgt aagaacgatg cccaattccg
      781 ttccaaaaga actgcattct ataaaaaaag cttttataaa ctatgaatcc ggcattcgtt
      841 tagccctcga attgccttat tcaaatgcca aaatagaaaa tctgcatacc cacatcaaag
      901 cattgaaacg agtcgcttat ggctttcgaa gctttcggaa aatgaagacc agaattttct
      961 tactaaataa tctgattacc tatgaatcaa aaaacatcta aagtagaaaa ggaattctac
     1021 cttagatgtt ct
//
LOCUS       DAFKHN010000223         1008 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.234, whole genome shotgun sequence.
ACCESSION   DAFKHN010000223 DAFKHN010000000
VERSION     DAFKHN010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.234"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..498)
                     /locus_tag="LY912_003021"
     CDS             complement(<1..498)
                     /locus_tag="LY912_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956618.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPA"
     gene            complement(623..>1008)
                     /locus_tag="LY912_003022"
     CDS             complement(623..>1008)
                     /locus_tag="LY912_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956619.1"
                     /translation="RKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIE
                     NQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTY
                     NQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          315 a          155 c          162 g          376 t
ORIGIN      
        1 tgctggatag ttttctctaa aaaaagaaac atcaagtgga aattcatcag ctttattaat
       61 agtgtaatgc aaaagtttaa aatgtatttt ggttaactct cttcggatca attggctcgt
      121 ctcttctcgc aacagattaa actgattttc aaaactttca atgaatcgtt cattcaacca
      181 ttcgattgtt tcatcttcat tttttctcaa gtatttttga tccaatttat catgaagata
      241 aagccaagag agtgtcttat tgataaaaat aacggatttt tctcctaata ctccttttaa
      301 gtggtaaaat cctatatccg aaaaaaatag cgactgattg ctagcaatat ctaaagaatc
      361 agcttgttca gccaacaggt tgattgctaa aaagtggaat aatttctttt tttcataagc
      421 agacagagga taatactgtt ttaaatcttt taacattttt tctgttttta taattatagg
      481 tagcgtatac aattccacaa aacttatctc tgttgagtta aaaagattat ataaaaaaag
      541 ccgaatgttt ttaggattcc ctgtcaactt gggagcgtca ataattttgt gtaaataaat
      601 tgtcctcctg caaaataatt agttactcag taaacattga aactaatgta tcggttacct
      661 gttgaaaacc tttatggctt ctgtttagaa atttttgatt gtatgtatca aaaatgctga
      721 ctagaaagcg ttctagtgat tcttcatttt gaaactgctc ttttctacgg ctgtatcttt
      781 taatttgctt attgaaagac tcgattagat tggttgagta aatggttcta cgaatgctag
      841 gtggaaaatc ataaaaagtt aataagtctt ggttttctat gagtgactgc gtcactttag
      901 gatagttttt cttccatttc tcaatcatgc cggataagaa ggtattcgct tcttcttttg
      961 agttagcttg ataaacagcc ttaaagtcat cacagatttc ttttcggt
//
LOCUS       DAFKHN010000224          994 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.235, whole genome shotgun sequence.
ACCESSION   DAFKHN010000224 DAFKHN010000000
VERSION     DAFKHN010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.235"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..>994)
                     /locus_tag="LY912_003023"
     rRNA            complement(<1..>994)
                     /locus_tag="LY912_003023"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          209 a          307 c          225 g          253 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatg
//
LOCUS       DAFKHN010000225          910 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.237, whole genome shotgun sequence.
ACCESSION   DAFKHN010000225 DAFKHN010000000
VERSION     DAFKHN010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.237"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..355
                     /locus_tag="LY912_003024"
     CDS             <1..355
                     /locus_tag="LY912_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956620.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
     gene            615..910
                     /locus_tag="LY912_003025"
                     /pseudo
     CDS             615..910
                     /locus_tag="LY912_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          353 a          106 c          190 g          261 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtaggtgaaa aagtttaaaa agaaaatata tttaggattg gttgttgggg
      661 tgagtatgtt tgggttcatg gctcatacta aacaagtaac tgcagatact aaccaaaaag
      721 aaaggattat gagccaatta gatgactctc aaataagtat gtacccaatg agctaattgt
      781 cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa atttattggg
      841 tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg attgtaataa
      901 gcgagatcaa
//
LOCUS       DAFKHN010000226          904 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.238, whole genome shotgun sequence.
ACCESSION   DAFKHN010000226 DAFKHN010000000
VERSION     DAFKHN010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.238"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            25..873
                     /locus_tag="LY912_003026"
     CDS             25..873
                     /locus_tag="LY912_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBM6956621.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT          315 a          152 c          183 g          254 t
ORIGIN      
        1 ctttgaaacg aggaaattaa acacatgaaa cttgcagtag ttacagatag ttcggcatat
       61 ctgccggaac gtatcaagaa ccatcccgac ttattcgtta ttccaatccc tttgattatg
      121 gatgggaaaa tttataacga aggaatcgat atcgaagcgg atgaatatta tggactttta
      181 aaaaacagta aagattttcc tactacttca caacctgtcg taggggaagt tttgggttta
      241 tatgaggaat tgaaagagaa agggtatgac acgattttaa gtatccatct ttcttcaggg
      301 atttctggct ttgtcaacac attatttgcg atgaaagatg acatcagcgg agtaacggtc
      361 attccttatg actctaagat cactagtatg ccgatgggac acatggtaga agctgcctta
      421 gacttaaatg atgaaggtca gtcccttgat gaaatacttg cacatatcga tcgaatccga
      481 gataatacct atgcttatct gattgtagat gatttgaaca atttagtacg aggaggacgt
      541 ttgacaaatg gtgcagcgct gattggcagc ttattaaaaa tcaaaccgat cctgacattt
      601 tctgaaggga aaattgtttt attcgaaaaa atccgttcaa gtaaaaaagc atttgctcga
      661 gctgaagaaa ttattggtag aagaaataac gaaatacaac cgccagtcaa actttacgtg
      721 atacatgcaa ataatttaga agtagcgatt gcggagaaag agaaattgca gaaaaaatat
      781 ccaaatgcag aaatcgaaat tggtcatttc ggaccagtca ttggtacaca tttaggtgaa
      841 aaagccatcg gcattgccat ttcagcgcaa taattccttt tattcaaaaa acataccaaa
      901 aata
//
LOCUS       DAFKHN010000227          890 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.239, whole genome shotgun sequence.
ACCESSION   DAFKHN010000227 DAFKHN010000000
VERSION     DAFKHN010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.239"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..888
                     /locus_tag="LY912_003027"
     CDS             <1..888
                     /locus_tag="LY912_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBM6956622.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DAFKHN010000228          863 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.241, whole genome shotgun sequence.
ACCESSION   DAFKHN010000228 DAFKHN010000000
VERSION     DAFKHN010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.241"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..846
                     /locus_tag="LY912_003028"
     CDS             <1..846
                     /locus_tag="LY912_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBM6956623.1"
                     /translation="LMKWIGANSFRTSHYPYSEEIMRLADREGIVVIDEVPAVGLHLN
                     FMATLLDDNVEKHNTWKEIRTENSHKTVIKELIERDKNHPSVVMWSIANEPDSDSEGA
                     KEYFEPLVELTKELDPQKRPVTIVTYLKSTPDVCKVGDIVDVLCLNRYYGWYVSGGDL
                     AHAKYLLKKELDGWMERCPDTPIMFTEYGADTVAGFHDTVPTMFTEEYQVAYYEANHE
                     VIDTCENFVGEQVWNFADFATSQGILRVQGNKKGIFTRDRKPKMIAYYLQKRWSSIPN
                     FSYKK"
BASE COUNT          315 a          113 c          183 g          252 t
ORIGIN      
        1 ttaatgaaat ggataggtgc taattctttt agaacatcac attatcctta ctcagaagaa
       61 attatgcgat tagcagatcg agaaggtatt gtagttattg atgaagtacc tgcagtaggg
      121 ttacatttaa atttcatggc cactttatta gatgataatg tggaaaaaca taatacgtgg
      181 aaagagatac gaacagaaaa ttctcataaa acggtgatca aggaattgat agaacgcgac
      241 aagaaccacc caagtgttgt aatgtggtct attgcaaatg aaccagattc ggattccgaa
      301 ggtgctaaag aatattttga acctttagtt gaattaacta aagaacttga tccgcagaaa
      361 agacctgtaa caatcgttac ttatctaaaa tcaacgccag atgtttgtaa ggtaggagat
      421 attgtcgatg ttttatgttt aaatcgttat tatggttggt atgtttcggg aggggatctg
      481 gcacatgcaa aatatctgtt gaaaaaagag ctagatggat ggatggaaag atgtcctgat
      541 acgccaataa tgtttacaga atatggagca gatacagtag ctggatttca tgatacagta
      601 ccaacaatgt ttacagaaga gtatcaagtg gcttattacg aagcaaatca cgaagtaata
      661 gatacatgtg aaaattttgt tggtgaacaa gtgtggaatt ttgcagattt tgcaacaagt
      721 caagggattt taagagtgca aggaaataag aaaggaatct ttactagaga tagaaaacct
      781 aaaatgattg cttactatct acagaaacga tggtcatcaa tacccaattt cagttataaa
      841 aaataatttg gattttttaa gaa
//
LOCUS       DAFKHN010000229          856 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.242, whole genome shotgun sequence.
ACCESSION   DAFKHN010000229 DAFKHN010000000
VERSION     DAFKHN010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.242"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            19..>856
                     /locus_tag="LY912_003029"
     CDS             19..>856
                     /locus_tag="LY912_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBM6956624.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDE"
BASE COUNT          292 a          149 c          166 g          249 t
ORIGIN      
        1 tataaggagt gagtacaaat gacctatacc catcttacaa cggatgaact tgtaatgata
       61 gagtcttatt tcaaaataaa tcaatctgtt gcgaaaactg cgcatttctt gaatcgttca
      121 agacaaacga tccataaagt atacctgttc ttcaagcaag gaaaatcagc cttagagtac
      181 tatcaacagt ataagaaaaa caaatcaaac tgtggtagac gcccgcttgt tttacctgag
      241 gaacaatcag aatatattca aagaaaggtt gttcaaggat ggacacccga tgtgattgtt
      301 ggtcgtgcag cgtttcctat tcgttgttct gctcgtacca tttatcgtat gttcaaaaag
      361 gggctattta atccttctga cttaccgatg aaaggcaagc gtaaaccaaa tggacatcaa
      421 gaaagacgtg gaaaacaagc tttccgtcgc tctattcatg aacgtgaaaa agattatagc
      481 caattctcaa atgagtttgg tcaccttgaa ggtgacacta tcgtaggttt gaaacataaa
      541 agtgctgtaa ttaccttagt tgagcgatta tcaaaagtta tcatcacatt gaaaccgtgt
      601 ggtagacaag cgattgatat tgaaaacaaa ttaaatcatt ggtttgaatc tgtaccgaaa
      661 aatctattca aatccatcac ttttgattgt ggaaaggaat tttcaaattg gaaacagatc
      721 agtaatgcca atgatattgc catttatttc gctgatccag gaacgccgtc tcaaagaggc
      781 ctaaacgaga attctaacgg attgttacgt agagatggtt tattgaaatc tatggatttc
      841 aattcagtag atgaat
//
LOCUS       DAFKHN010000230          828 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.243, whole genome shotgun sequence.
ACCESSION   DAFKHN010000230 DAFKHN010000000
VERSION     DAFKHN010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.243"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..805
                     /locus_tag="LY912_003030"
     CDS             <1..805
                     /locus_tag="LY912_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HBM6956625.1"
                     /translation="KQKAIAIKKELESFGLLLQKQMGFNKQLGKNNPNRLYLAELKVS
                     ENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAESLGAQEGMKIIPCQNVDKSEG
                     MKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFETIMTNDSIATFVPERVLNLIKT
                     FSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDSYYVNAEQELYTTLLKAYQKLK
                     TEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYASSPSTITKDWLE"
BASE COUNT          345 a          130 c          142 g          211 t
ORIGIN      
        1 aaaacaaaaa gcgatagcaa tcaaaaaaga gttggaatcc tttggtttat tattacaaaa
       61 gcagatggga tttaacaaac agttagggaa aaataatcct aatagactat atctagcaga
      121 attaaaagtc tcagaaaatg atatctactt actcgaaaaa tttgatagag agaataggga
      181 aaacgttgat aaatcagagg gtatgaaaat catacccacc ctcgacgaaa aatcagacgc
      241 tgaatccctt ggggctcaag agggtatgaa aatcataccg tgccaaaacg ttgataaatc
      301 agagggtatg aaaatcatac cagaacttaa taataatata ttagacacta atagacacaa
      361 tatagacact gaaaaagacc gcctacaaga tcaattgttg ttagacaatt ttgagacaat
      421 tatgacaaac gacagcattg ctacgtttgt ccctgaacga gtattaaatt tgataaaaac
      481 attttcttca agttacagtg aagctcaaaa aaccgtccag actattcata atgcaaagaa
      541 aaaagctgaa atagaaagtg atatttcgat agtttttgaa gaactcgata gttattatgt
      601 caatgcagaa caagaattat acacgacact gttaaaagcc tatcaaaaat taaaaaccga
      661 aaaagtcgaa aatatccaga acctgatttt tgtctatgta aaaaattggt ttatcgaaaa
      721 accaatagct gctaaagtat caagtgaaaa acgtttgaat tatgcaagct ccccaagcac
      781 tattacgaaa gactggttag agtgaaactt tactgacaaa gtgattgt
//
LOCUS       DAFKHN010000231          828 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.244, whole genome shotgun sequence.
ACCESSION   DAFKHN010000231 DAFKHN010000000
VERSION     DAFKHN010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.244"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..89
                     /locus_tag="LY912_003031"
     rRNA            <1..89
                     /locus_tag="LY912_003031"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            183..298
                     /gene="rrf"
                     /locus_tag="LY912_003032"
     rRNA            183..298
                     /gene="rrf"
                     /locus_tag="LY912_003032"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            312..384
                     /locus_tag="LY912_003033"
     tRNA            312..384
                     /locus_tag="LY912_003033"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:345..347,aa:Val,seq:tac)
     gene            388..460
                     /locus_tag="LY912_003034"
     tRNA            388..460
                     /locus_tag="LY912_003034"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Lys,seq:ttt)
     gene            468..549
                     /locus_tag="LY912_003035"
     tRNA            468..549
                     /locus_tag="LY912_003035"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:502..504,aa:Leu,seq:tag)
     gene            567..639
                     /locus_tag="LY912_003036"
     tRNA            567..639
                     /locus_tag="LY912_003036"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:600..602,aa:Thr,seq:tgt)
     gene            651..722
                     /locus_tag="LY912_003037"
     tRNA            651..722
                     /locus_tag="LY912_003037"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:683..685,aa:Gly,seq:gcc)
     gene            739..824
                     /locus_tag="LY912_003038"
     tRNA            739..824
                     /locus_tag="LY912_003038"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:773..775,aa:Leu,seq:taa)
BASE COUNT          214 a          181 c          230 g          203 t
ORIGIN      
        1 cctgagagat gatcaggtag ataggtcagg agtggaagta cagtgatgta tggagcggac
       61 tgatactaat cgatcgagga cttaaccaat aggttaaaag aaaagaactc ggaaaaaact
      121 tatgtaactt caaatccagt tttgagtgaa caaaatttac tcaataaaag ataacaccac
      181 agtgtggtgg cgatagcgag aaggatacac ctgtaaccat gccgaacaca gaagttaagc
      241 ttcttagcgc cgattgtagt gaggggttgc cccttgtgag agtaggacgt cgccacgctt
      301 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
      361 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      421 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      481 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      541 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      601 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      661 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      721 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      781 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttc
//
LOCUS       DAFKHN010000232          811 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.246, whole genome shotgun sequence.
ACCESSION   DAFKHN010000232 DAFKHN010000000
VERSION     DAFKHN010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.246"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..672
                     /locus_tag="LY912_003039"
     CDS             <1..672
                     /locus_tag="LY912_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBM6956626.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          298 a          126 c          152 g          235 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac cgtcaggttt a
//
LOCUS       DAFKHN010000233          770 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.248, whole genome shotgun sequence.
ACCESSION   DAFKHN010000233 DAFKHN010000000
VERSION     DAFKHN010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.248"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(109..>770)
                     /locus_tag="LY912_003040"
     CDS             complement(109..>770)
                     /locus_tag="LY912_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HBM6956627.1"
                     /translation="RIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQ
                     PLEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLT
                     DVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQY
                     QFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEA
                     A"
BASE COUNT          213 a          177 c          148 g          232 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgttttcg cttcattaca agctgttcgt tgccctttaa aatgagcgat
      721 cgtataggta gatgtcaatc cgcggcgttt catgattcga ccgattcggc
//
LOCUS       DAFKHN010000234          766 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.249, whole genome shotgun sequence.
ACCESSION   DAFKHN010000234 DAFKHN010000000
VERSION     DAFKHN010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.249"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(246..620)
                     /locus_tag="LY912_003041"
     CDS             complement(246..620)
                     /locus_tag="LY912_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956628.1"
                     /translation="MKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLWKYKILFL
                     FWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
BASE COUNT          246 a          120 c          126 g          274 t
ORIGIN      
        1 agacaaatta tcaaagaata tattaaaagc tctcagaagc cttctgagag cttttaaatt
       61 gctatgtatt gtactgcatc tgctcaaatt gattttcttt tcatgcttac catgtatcta
      121 attttccatc aagtaatttt tagatatgta ttgagtaata aatagcaaat ttgcttgata
      181 taagctcgaa ttaggtgctt tgtaatgtgt taggataaaa ttatacaaga aaatgtcaaa
      241 agctctcaga acgcttctga gagcttttta tcggtaggct tgtttaacgt gatcttgaag
      301 gatacccttt tgatgtttct ctcgatccct gcatcgctaa ttactaagtg ttcttcaagt
      361 gtgatgtagg tatataaatt aagcatcaaa atggtgtaga taagcaaaaa actccctaaa
      421 actaagtgtt gattataaaa atctgactta taaaaaagaa ctgagaatgt tagtgttgat
      481 tcccaaaaaa gaaacaaaat tttgtatttc caaagatagt ggatcaagcg ctgtgcttta
      541 cccatctcaa ataatttata ataacctgct aattgatcag caagcgtatc gttaacggtt
      601 tctgtttgtg tttgtttcat ctttctcttc tcctgtttca attaatctaa aatttcagat
      661 tgagcaagca actcattgtg gtagtcggtt tgaaattcaa ataacaattt tgccttctta
      721 acgaggttta aagcgttcgt tagtgattca cttaatgctt caacat
//
LOCUS       DAFKHN010000235          749 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.250, whole genome shotgun sequence.
ACCESSION   DAFKHN010000235 DAFKHN010000000
VERSION     DAFKHN010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.250"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            1..660
                     /locus_tag="LY912_003042"
     CDS             1..660
                     /locus_tag="LY912_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBM6956629.1"
                     /translation="MIGLMLVIFSGKQYADNILLWGGEDNIEKINNNLTILDTALENK
                     EQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKTNLENQLSAKDS
                     ELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQSTINSLNQQINQM
                     LSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTANKAQQIVNEHTI
                     Q"
BASE COUNT          350 a           94 c          109 g          196 t
ORIGIN      
        1 attataggat tgatgttagt aattttctcc ggaaagcaat atgctgataa tattttatta
       61 tggggagggg aagataatat tgaaaagatc aacaacaatt taactatatt agacacagct
      121 ctagaaaata aagagcaaaa aattagtatt ttaaattcac aattgtcttc aaacaaccaa
      181 actcttgaac aactaagaac taatattgaa gtttccaaac aaaaagtggc atctttagaa
      241 aacgacaaga atcaattagt atcagagaaa actaatttag aaaatcaatt gtcagcaaaa
      301 gactctgaat tgcaaggaaa acaaaatgaa attaatgcga aaatagacga aattaaccaa
      361 aaagtagctg aaataaatcg attaaatagc gattggaata atcgtttaca aaatgaaaag
      421 aacaaattta atgaagaaca atctactatt aatagtttaa accagcaaat taatcaaatg
      481 ttgagtgaaa aaaataacat tcaaaatcaa ctgcaagcta ctcagcaaaa gctagaagaa
      541 gaaaagtcaa aaaatagtag tttgaataat tacattgaaa agcttcaaaa agctaaaaat
      601 gatgtagagg ataccgcaaa taaagcacaa caaattgtaa atgaacatac aatccaatag
      661 atatagtttt aatttaacaa atggtatgtt tggagataat gagatagaat ataaatgtca
      721 taatattata caatctaaac accgtttcc
//
LOCUS       DAFKHN010000236          704 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.251, whole genome shotgun sequence.
ACCESSION   DAFKHN010000236 DAFKHN010000000
VERSION     DAFKHN010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.251"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(14..400)
                     /locus_tag="LY912_003043"
     CDS             complement(14..400)
                     /locus_tag="LY912_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956630.1"
                     /translation="MKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRFEVLKIQKNE
                     LLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTDVVMITDIYV
                     EDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          221 a          130 c           84 g          269 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg ttcctttatt tttattaaca agttttatca
       61 caggcttcat atatttgatt atatcttcat cttctacata gatatctgtt atcattacga
      121 catctgtact atttcgattg agtactttca cttgatctcc agcattgatt ttccctctaa
      181 atcttttagg aatgaaccaa ctatacatat gattagcatc accaaaatgt gcttttatcg
      241 cattctcagg atataactta ttcaatagtt cattcttttg aattttcaaa acttcaaatc
      301 tatacttatc atcttctgct aatctaaata aatcttctaa acgcatgttt tctaactgta
      361 agttttgaaa atcttccggt ataaattttc tatatttcat taataatgaa cgcccagccc
      421 gatttattag aatctggcca ttttggtcat ctctataaag aattccgtaa cccatcaacg
      481 ccaatagcac acgtgacgtt ttgttacttg taatattcat atttccttga ttacctgagg
      541 caatgaaaga cttatctact tgaattaggg tgaaattctc attcaaatat ggtagtaaaa
      601 ttaatatatg tgaaaatcga atcttgagat agctattccc cttgagatat tcactgatac
      661 ttctactcaa atcatttaaa tttttataat tatttgtatg gaac
//
LOCUS       DAFKHN010000237          703 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.252, whole genome shotgun sequence.
ACCESSION   DAFKHN010000237 DAFKHN010000000
VERSION     DAFKHN010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.252"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..594
                     /locus_tag="LY912_003044"
     CDS             <1..594
                     /locus_tag="LY912_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBM6956631.1"
                     /translation="KKEFPIPISWTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGG
                     GALQEGRFIEGFSHPEMGHMLVVPHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKG
                     QEVAEDDPYWEIEASYIAQCAYNTTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVN
                     GYVETPELSKYIVTPALEDNAGTLGCLALAREAVLHS"
BASE COUNT          198 a          138 c          179 g          188 t
ORIGIN      
        1 aaaaaagaat ttccgatccc gatttcttgg acaacagatg tcaatgcggc tgcctatggt
       61 gagtatgtct tcggcagtgg caaaggattg agcagtgtcg tttactatac gatcggtacg
      121 ggtgttggcg gcggtgcctt acaagaaggg cgctttatcg aagggtttag tcatccagaa
      181 atggggcata tgctcgtcgt ccctcatcca aaagatgact ttgctggcag ctgtccattt
      241 catggcaact gtttagaagg gatggccgct ggacccgcca tcgaaaaacg cttagggaaa
      301 aaaggacaag aggttgcaga agatgatcct tattgggaaa tcgaagcctc ctatattgct
      361 caatgtgcct acaatacaac cttgatgttt tctccagatg tgatcatttt tggcggtggt
      421 gtgatgaaac aacgccatat gctgcaaaac gtccacgacg catttgcaaa attggtcaat
      481 gggtatgtcg aaacacctga gttaagcaaa tatatcgtga ccccagcatt agaagacaac
      541 gctggaacgc tcggttgttt ggcattggct cgagaagcgg tcttacattc ataaacgaaa
      601 aaaggctctt cgacatttag tgttggtaga gaaagataca actgaaaatt tagtcataac
      661 cagttaggca gagtgcttaa ctggtttttg ttttacttgg aag
//
LOCUS       DAFKHN010000238          695 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.253, whole genome shotgun sequence.
ACCESSION   DAFKHN010000238 DAFKHN010000000
VERSION     DAFKHN010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.253"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(53..628)
                     /locus_tag="LY912_003045"
     CDS             complement(53..628)
                     /locus_tag="LY912_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBM6956632.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          124 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaac
//
LOCUS       DAFKHN010000239          670 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.254, whole genome shotgun sequence.
ACCESSION   DAFKHN010000239 DAFKHN010000000
VERSION     DAFKHN010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.254"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..360)
                     /locus_tag="LY912_003046"
     CDS             complement(<1..360)
                     /locus_tag="LY912_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBM6956633.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDK"
     gene            complement(371..>670)
                     /locus_tag="LY912_003047"
     CDS             complement(371..>670)
                     /locus_tag="LY912_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBM6956634.1"
                     /translation="ITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQYLEFLLVP
                     VLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFLSILI"
BASE COUNT          228 a          116 c           96 g          230 t
ORIGIN      
        1 tttatccata tgctcttttg taaatccaaa gttttccatc gaaaatacta actcactcgt
       61 tgtatttgtt gtaaagaatt gtcctctagg atcttgactt acgtagccaa tattttttga
      121 tatactttct tgtgttaagg attgtagcga gttattttca aataaaattt ccccaaccaa
      181 ttttccgtca taaagtcttg gaataagtcc attcattaac tttaatagtg tggatttccc
      241 actcccagaa gaaccagtaa tcaatgtaag actgcctttt tttattgaaa aattaaggtc
      301 aacaagcgct tgttccttaa catccttata tgaaaaagaa acattgttaa attcaaacaa
      361 ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt aacggaaaac aggatgatat
      421 agtctaataa gctcatgttt gttttatagt aagaacttct tttcacagga gattctatcc
      481 cctttgttat tgcattagcg gtcatttctt cagcaatcat agttgcacgt ataagaacgg
      541 gaactaacag aaattccaaa tattgcagag gctgaaaaaa agacaagcga atgtttctca
      601 tttttaaaga ttctttaatc attcttattt cagaacgata agtcggaaag aatctgatca
      661 ctactgtaat
//
LOCUS       DAFKHN010000240          666 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.255, whole genome shotgun sequence.
ACCESSION   DAFKHN010000240 DAFKHN010000000
VERSION     DAFKHN010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.255"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..>666)
                     /locus_tag="LY912_003048"
     CDS             complement(<1..>666)
                     /locus_tag="LY912_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBM6956635.1"
                     /translation="DKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFE
                     QLDPGEQKRFFEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNV
                     FNRQELLWLQDKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLA
                     VKKDEWTAYSDKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVIS
                     ERD"
BASE COUNT          171 a          141 c           90 g          264 t
ORIGIN      
        1 aatcacgctc cgatataaca acatttttgg ttggtttctt ttctgttttc attatttctt
       61 ttcccaaacc aaacatggac ttttcacccg ttggcacttc aacacttttc atgtgtcgtt
      121 tcgctggtac ttctaaatct gatttaactt tatcgctata agcagtccat tcatcttttt
      181 taactgctaa atttttttct agaaaatcaa tctctttttc caaagtttgt tttttaaatt
      241 tagctgtctc aatatgttta cggtcagagc cacgttcacc acgcttcaac tcaaaaccct
      301 gttttttcat atgctcgggg aatttatctt gtagccataa cagttcttga cgattaaaca
      361 cattttttcc ttgcagtttt ccatcacgca taggcacaac acctaaatgc atgtgagggg
      421 tttgctcatc attatgaact gttgcataag caatattttg cttgccatat cgttcggaaa
      481 ataatttata actttcctca aaaaatcgtt tttgttctcc tggatccagt tgctcaaaaa
      541 aatctcggtc agatgttact agcaactcat ttacaagaac agcatctttc ctcgtttttc
      601 ttgtacctgt tttttgtgat tcaataattt ctttgacacg ttcgttgtaa tcaatatttt
      661 tatcat
//
LOCUS       DAFKHN010000241          664 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.256, whole genome shotgun sequence.
ACCESSION   DAFKHN010000241 DAFKHN010000000
VERSION     DAFKHN010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.256"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..>664
                     /locus_tag="LY912_003049"
     CDS             <1..>664
                     /locus_tag="LY912_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBM6956636.1"
                     /translation="NIEIIVVDDGSPDRSGEIAEEYKKKDMRLKVIHQVNGGLSAARN
                     SGLDSATGDFVCFIDSDDWIEPDYLELLYFGTQTYGADISVLKIKKISSLEQLKEHTI
                     AERKWEIFDREQAMKNLFINNKIGYSANNKLFNRNLFDNIRFPLGKLMEDKATTYLLI
                     DHSEKVAVNSSAKYHYYQSPKSILRGSFNPRIFDSFEVHEDILVFIDKFYPELSINVR
                     TRY"
BASE COUNT          249 a           84 c          125 g          206 t
ORIGIN      
        1 aaatattgaa ataatagtag tcgatgatgg ttccccggat cgaagtgggg aaattgcaga
       61 agaatataaa aagaaagata tgcgattaaa agtgatacat caagtgaatg gtggtttaag
      121 tgcggctagg aattctggtc ttgattctgc aacaggagat tttgtgtgct ttattgacag
      181 cgatgattgg atagaaccag actatcttga gttactatat tttggtacgc aaacttatgg
      241 agcagatatc tcggtgctaa aaataaaaaa gatttcaagt ttagaacaac taaaagaaca
      301 tacaattgct gagagaaaat gggaaatatt tgatagagaa caagcaatga aaaacttatt
      361 tataaataat aaaattggct attctgcaaa taataaatta ttcaatagaa atttatttga
      421 taatataaga ttcccactgg gtaaattaat ggaagataag gctactactt atttgttgat
      481 cgatcattcc gaaaaagttg ctgtcaattc atctgctaaa tatcactatt accaaagccc
      541 taaaagtata ctgagaggaa gcttcaatcc tagaattttt gattcttttg aagtccatga
      601 agatatacta gtattcatag ataagtttta tccggaatta tcaattaatg ttagaactcg
      661 ctat
//
LOCUS       DAFKHN010000242          656 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.257, whole genome shotgun sequence.
ACCESSION   DAFKHN010000242 DAFKHN010000000
VERSION     DAFKHN010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.257"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            245..>656
                     /locus_tag="LY912_003050"
     CDS             245..>656
                     /locus_tag="LY912_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBM6956637.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYW"
BASE COUNT          214 a           83 c          123 g          236 t
ORIGIN      
        1 cctaatataa aaaggttgtg acatggcttg tgtcgcaacc tttttttgtc gcacaaataa
       61 ttaatcggat attttatgtt catatttttt gtgatcaacg agaactgatg gggcaaagat
      121 acattttaga tacttttaac tgttaattta caaaacaagg tgaaacgaat agaaaaatga
      181 aaaaatcgat acggaagaat atgtttgatt aaaacatgca tgaagagaag gaggttgatg
      241 atacatgaaa aaaatatatt caaaggaaat cgattgtttt agaggcattg ctgttttagc
      301 agtgatattt tatcatttgc caaatagttt gctgccaggc ggattgcaag gagtaacgat
      361 cttttttgtg gtttctggtt ttttaatggc taaaaatacg ataagagatg aaaaaaacag
      421 acaattcagt tttttacatt tttactataa gcgtatcaaa cgtatttatc catttttact
      481 gttttctttg gtcgtattca ttttcatact agggattagc aacattcgat tgataggaaa
      541 cattcgtagt gagctaccca gtttgatttt tggctataac aattggtggc agctgaatca
      601 aggagtatct tattttgact cttactttaa tgcttcttta tttaaacatt attggt
//
LOCUS       DAFKHN010000243          647 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.258, whole genome shotgun sequence.
ACCESSION   DAFKHN010000243 DAFKHN010000000
VERSION     DAFKHN010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.258"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..641
                     /locus_tag="LY912_003051"
     CDS             <1..641
                     /locus_tag="LY912_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBM6956638.1"
                     /translation="LYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPD
                     NYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWF
                     SRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNG
                     LPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT          221 a          124 c          107 g          195 t
ORIGIN      
        1 cactttatcg tttattttct aaaggaatat ttgatattga cacactaccg atgaaaggta
       61 aaagaaaacc caatggccat caggaaaaac ggggaaaaca acagtatcag cgctcaatcc
      121 atgatcgacc tgataattat cctgatttca attctgagtt tggtcacctt gaaggtgata
      181 cgatcgttgg cattcatcat aaaagtgccg tcattacttt agttgaaaga ttatctaaag
      241 tcattatcac gattaaaccc aacggccgta aggcattaga tattgaaact gcccttaatc
      301 aatggttttc tcgcttccct aaaaacttct ttaaatctat tacgtttgac tgtggaaaag
      361 aattttctaa ctggaaagcc attagtaacc aacatgatat tgatatatat tttgcggacc
      421 ctggaacacc ttctcaacgc ccattaaacg agaattctaa cgggattctg cgtcgtaatg
      481 gactgccgaa atcaatggat tttagaaaag tgaatcagac atttatttcc agtgtcagca
      541 atcaacgtaa tcatattcca agaaaatcat tgaattacag aacaccaatc gaaatatttt
      601 tgagctatgt acaagaagca ttttattcta gcttaatttg acaaatc
//
LOCUS       DAFKHN010000244          636 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.259, whole genome shotgun sequence.
ACCESSION   DAFKHN010000244 DAFKHN010000000
VERSION     DAFKHN010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.259"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..149
                     /locus_tag="LY912_003052"
     CDS             <1..149
                     /locus_tag="LY912_003052"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956639.1"
                     /translation="KKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDYSALGLFS
                     IGYW"
BASE COUNT          251 a           76 c          103 g          206 t
ORIGIN      
        1 taaaaaagat aggcagtggt atttcttcag taagattaaa agagaaagaa tatactcaaa
       61 agattattca tattcctaag cctgaaatta agcgttttga gataaaagac tattctgctt
      121 tagggctgtt ctcaattggt tactggtgat aaaaaataag aatactaaaa ctatacgtag
      181 aatataagta atcggcatca atcctaatta tgtgattgaa tgccgatttt tgttacgcgc
      241 tatttttaat tatctgtaag aagaataatt ttattttact catattcgtt ttcactttga
      301 agaagtaaat tgcaatttct tataagttaa gcagctatgc aaaaggctat ttattctatt
      361 gtgaaatata agatgtagtt gaaacaggat atatagaatc aaaatacgaa tcttattttg
      421 atttttctag ttttttgaaa aaagcaccct ttgatcgttg tattagtgga aaagagaaaa
      481 aggagcatac ttatcatgtc acaaaactac aactaaatat ctaaacaaca ccaatttgat
      541 gcctattgaa aaaaagtatt gcgaaatgaa gccaagtcta ttagaaaatg aaataataga
      601 ataaaagaaa atgggaaacc gctgaatgat gtaaat
//
LOCUS       DAFKHN010000245          593 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.261, whole genome shotgun sequence.
ACCESSION   DAFKHN010000245 DAFKHN010000000
VERSION     DAFKHN010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.261"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            1..593
                     /locus_tag="LY912_003053"
                     /pseudo
     CDS             1..593
                     /locus_tag="LY912_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          234 a          100 c          112 g          147 t
ORIGIN      
        1 agaaaaagat aatcttacgc ctgaacaaaa agaattgtta gaactacgta aaagaaacca
       61 gcaattagaa atggaaaatg atattttaaa gcaagcagcg ctgatattcg gacgaagaga
      121 caagtaatcg atgcgaataa gcatctttac cctatatcag cgatgtgcag aatattaggt
      181 ctatcacgtc agtcctatta ttatcaatca aaaccaaaga aagacgaatc agaacttgaa
      241 gaagtagtcg ctgaagaatt tatccgcagc cgaaaggcct acggctcaag aaaaataaaa
      301 aaagccttat caaaacgagg cattcagatc agccgacgaa aaattagtag aatcatgaaa
      361 aatagaggat taaaatcgag ctatactgtt gcttatttta aagtacatca ttctacttgc
      421 aatgaagcca aaacgacaaa cgtattgaat cgtaaattct taagagacaa cccattagaa
      481 gcgatcgtaa cagacttgac ttatgtacga gtcgggaaaa aatggaatta tgtctgtttc
      541 attttggatc tgttcaatcg agaaattctc ggctattctt gtggagaaca taa
//
LOCUS       DAFKHN010000246          591 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.262, whole genome shotgun sequence.
ACCESSION   DAFKHN010000246 DAFKHN010000000
VERSION     DAFKHN010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.262"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            26..>591
                     /locus_tag="LY912_003054"
     CDS             26..>591
                     /locus_tag="LY912_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBM6956640.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTT"
BASE COUNT          210 a          101 c          117 g          163 t
ORIGIN      
        1 gaaaaagata gcaggaggaa tgacgatgaa tcattttaaa ggaaagcaat ttcagcagga
       61 tgtgattatt gtagccgtgg gctactatct tcgttataac cttagctatc gtgaagttca
      121 agaaatctta tatgatcgtg gcattaacgt ttctcatacg acgatttatc gttgggtgca
      181 agaatatggc aaactactct atcaaatttg gaaaaagaaa aataaaaaat ccttttattc
      241 atggaaaatg gatgaaacgt acatcaaaat taaaggaaaa tggcattatt tgtatcgagc
      301 catcgatgca gatggtttaa ccttggatat ttggttacgt aaaaaacggg acacacaagc
      361 agcctatgct tttcttaagc ggttagtgaa gcagtttgat gaaccgaagg ttgtagtcac
      421 agataaagcc ccctctatta caagtgcctt taagaaacta aaagaatacg gcttttatca
      481 agggacagaa catcgtacca ttaaatacct gaataatttg attgaacaag accatcgtcc
      541 agtaaagaga cgcaataaat tctatcgaag tttacgcact gcctctacca c
//
LOCUS       DAFKHN010000247          584 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.263, whole genome shotgun sequence.
ACCESSION   DAFKHN010000247 DAFKHN010000000
VERSION     DAFKHN010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.263"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            44..379
                     /locus_tag="LY912_003055"
     CDS             44..379
                     /locus_tag="LY912_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956641.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
BASE COUNT          226 a           66 c          105 g          187 t
ORIGIN      
        1 aatttcctag gaaaaatagt taacataaaa ggaatgaatt gttatgaaac aatatttaaa
       61 tgaatggaaa gcgatagagg ggtcattagt aacgcaaaga ataaaggaat tacctgattg
      121 cttagagaag gatcatttgt ttcaaatacg agaaatgttg aaaaaagaac agtttgatcc
      181 agaccaattt ttagtagtcg agtatccaac tattggagtg tactgttgta accatatcaa
      241 tgatggaaaa tattttatta ttcaggagta tggaggacag ttaactcctt tctatactac
      301 atgggaaatg agtgaagaag gaatcaataa ttttccatgt gaaagcatcg aagattcaat
      361 ttcacacacc gaatgttaat tgattataac tataaaaaag gattgaacat tatgttcaat
      421 ccttttttca atgaaatgtt ttccgccatt tcattgtttg gtgcgatttc tattttatta
      481 tatcaaaata aagagagatt ctaaagaaag aagagggaaa tatataaatc aagcgacagt
      541 atatttatta ttaaatgcta ttgtgagaat ataactaatt agtt
//
LOCUS       DAFKHN010000248          578 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.264, whole genome shotgun sequence.
ACCESSION   DAFKHN010000248 DAFKHN010000000
VERSION     DAFKHN010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.264"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(73..267)
                     /locus_tag="LY912_003056"
     CDS             complement(73..267)
                     /locus_tag="LY912_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956642.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(367..453)
                     /locus_tag="LY912_003057"
                     /pseudo
     CDS             complement(367..453)
                     /locus_tag="LY912_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          199 a          105 c           87 g          187 t
ORIGIN      
        1 caatacataa attatcatat ctgtatatgt catttaggta tttcagttat gttataatag
       61 ttttgctgtc tgctaccccg gcctaatctg gcaaggggag gaggagatat aatgaaatac
      121 ctttttgatt ttgtttttgc aatcaagcca cttgcagatg tagtgtgcag ttacctctgc
      181 aaatggcttg attgcaaaat tgccaaaaaa gacagtaagc ctacccgtta attctataat
      241 atagaaacgt aaaaaaaacc ccatcagcct gcacgctgat ggggtttggt gatataatga
      301 aatacctctt tgttactcat aattatacca taattagtca cgaatgcaac caatagaaaa
      361 aactacttag aacggtagat catcgctaat aacaatgcat tgtccaccaa atggattttg
      421 tgaagcatta aatacattgt tattaattgt cgctgctttt aactaggcct ctccccttct
      481 attataaaag aagatatata tcatttctta attacctact accttaaacc aaaatttaag
      541 tactacctaa tttaagtagt acttaaacaa tctaaaaa
//
LOCUS       DAFKHN010000249          557 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.265, whole genome shotgun sequence.
ACCESSION   DAFKHN010000249 DAFKHN010000000
VERSION     DAFKHN010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.265"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
BASE COUNT          205 a           88 c           64 g          200 t
ORIGIN      
        1 cacgataggt aactttaaac aaacatgaag agactttaat aagacttctt tatctgaaaa
       61 cacttttgtt tctctctttc ctttctacat cattaaatag tattttatac gttatctaaa
      121 atactattcc tctgtcaaaa taagctaact tacttcatta taaaatatcc acttatcgct
      181 ttcatgtata ttccaccgta aaaagtacat tttatcaccg agaactcatc atttttcatc
      241 atgatgaata ctatttacat atatctagtt caaagacaat aattattatg atccgttatt
      301 atctaagcac tatacagata ataggaattt ttcgtttcta aatattccaa tttgggaatc
      361 caataaaaat tttcgttcaa atacgtgtct attcgaactc ttttctagtt gttaattatg
      421 aagggggaag aaataaaaaa tacaatctat acacgaataa gaatattatc caaaaggagg
      481 ttttagaaaa gatttattat acgtaaaaag ctcaagacat tttcttagcc ataaggacat
      541 gtttgatatt taagaag
//
LOCUS       DAFKHN010000250          549 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.266, whole genome shotgun sequence.
ACCESSION   DAFKHN010000250 DAFKHN010000000
VERSION     DAFKHN010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.266"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            331..489
                     /locus_tag="LY912_003058"
     CDS             331..489
                     /locus_tag="LY912_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBM6956643.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
BASE COUNT          193 a           85 c           89 g          182 t
ORIGIN      
        1 tgtcttttta tacatgttta tcgttattaa tagtgaatag gaaaaaaact atttttgatc
       61 attgacaatt aaatacaatt tttgaataac gatccctgct attcgagcta gaaactcaag
      121 tacgccatga cctgattagc gacaaatact tagagatttc tttttgttct gggaaaacaa
      181 aatgccatga caatagcagc aaataatgat acttccgtaa ggctcgccgt aaactgggga
      241 gaggtgaaat tcctatgtgc ttacccaaag caattcaaaa atttcataac tactatttta
      301 ggagatgatt ttatagaatc cagagtctac ctgaataaaa aacaaacctg tgcatttcta
      361 ggaatcgata ataatactct agataagtgg attcgtatat ataatttccc agtaataaga
      421 gttggtggtg tagttcgctt tgacgtagaa gatattaaag actttatgaa tacatttaaa
      481 ataacttgaa attttcttct cgccgcatat actaaaatta gtgaaatata ctgccttact
      541 ttttttaag
//
LOCUS       DAFKHN010000251          544 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.267, whole genome shotgun sequence.
ACCESSION   DAFKHN010000251 DAFKHN010000000
VERSION     DAFKHN010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.267"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..>544)
                     /locus_tag="LY912_003059"
     CDS             complement(<1..>544)
                     /locus_tag="LY912_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBM6956644.1"
                     /translation="LDTNDDLQEELALEPINEKESYPISVPSSYNDLFETENIRNHVG
                     WVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNGKFITQHKGGFTPFESEINRFVK
                     DGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKKENLVNFDFFNYAGIHRPVKLYT
                     TPKDYISDITINTRITDLDA"
BASE COUNT          170 a          105 c           65 g          204 t
ORIGIN      
        1 cttgcatcca aatcagttat tcttgtatta atagtaatat cacttatata gtctttcgga
       61 gttgtatata acttaacagg tctatgaata cctgcataat tgaagaaatc aaaattaact
      121 aagttttcct tttttatatc cccattttcc tgtactgttt ccttcataat ccccacaggt
      181 aaagtactat cgtcaataat attgtttaca gcaactgtaa ttcgattatt cccgtctttt
      241 acaaaccgat taatttcaga ctcaaatggt gtaaacccac ctttgtgttg agtaataaac
      301 tttccattca aaaaaacttt tgcttcatgt gttgcagatc caaaacgaag aactaatctt
      361 tcttctaata atcttttagg aagagtcact tctttttcat accacaccca tccaacatga
      421 tttctaatgt tctctgtttc aaataaatca ttataagaag agggaactga aatcggataa
      481 ctctcttttt catttattgg ttctaaagca agttcttcct gtaagtcatc atttgtatct
      541 aatt
//
LOCUS       DAFKHN010000252          544 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.268, whole genome shotgun sequence.
ACCESSION   DAFKHN010000252 DAFKHN010000000
VERSION     DAFKHN010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.268"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..>544
                     /locus_tag="LY912_003060"
     CDS             <1..>544
                     /locus_tag="LY912_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBM6956645.1"
                     /translation="GERQKISIGCSLSLNSKLIILDEPSSNLDFKATKKLADLLCDLK
                     NKGFTIVIAEHRFYYLKELIDQVLFVKNRTVKTTTIQLLKTENNNALRKFDIFNSSIE
                     VPYIEKVSADVLKVEEITYENILKDINFDVKVGDVIGLVGKNGVGKTTLLRILMKIIR
                     PTKGKIIENKKNLSSPFLVM"
BASE COUNT          208 a           65 c           95 g          176 t
ORIGIN      
        1 gtggtgaacg gcagaaaatt tctattggat gtagtttatc gctaaactct aaattaatta
       61 tattggatga accgtcttca aatttggact tcaaagcgac taagaaactt gctgacttac
      121 tttgtgattt aaaaaataaa ggatttacta ttgttatagc tgaacatcgt ttttactatt
      181 tgaaagaatt aattgatcaa gttctatttg ttaaaaatag aactgtaaaa actacaacta
      241 ttcagttgtt aaaaactgaa aacaataacg cattaaggaa atttgacatt tttaatagtt
      301 cgattgaagt tccctatatc gaaaaggtaa gtgcagatgt attaaaagtt gaagaaatta
      361 cttatgaaaa tattctaaaa gacataaatt ttgatgtcaa agttggagat gttattggtt
      421 tggtagggaa aaacggtgtg gggaaaacaa ccttactaag aatactcatg aagattattc
      481 gccctaccaa aggaaagata atcgaaaata aaaaaaattt gtcatcgccg tttttagtaa
      541 tgca
//
LOCUS       DAFKHN010000253          539 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.269, whole genome shotgun sequence.
ACCESSION   DAFKHN010000253 DAFKHN010000000
VERSION     DAFKHN010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.269"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            400..>539
                     /locus_tag="LY912_003061"
     CDS             400..>539
                     /locus_tag="LY912_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBM6956646.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DL"
BASE COUNT          184 a           85 c          120 g          150 t
ORIGIN      
        1 aaaaccgaaa gacaataaaa attttattct tgctgagtct ggctttcggt aagctagaca
       61 aaacggacaa aataaaaatt ggcaagggtt taaaggtgga gattttttga gtgatcttct
      121 caaaaaatac tacctgtccc ttgctgattt ttaaacgagc acgagagcaa aacccccctt
      181 tgctgaggtg gcagagggca ggtttttttg tttctttttt ctcgtaaaaa aaagaaaggt
      241 cttaaaggtt ttatggtttt ggtcggcact gccgacagcc tcgcagagca cacactttat
      301 gaatataaag tatagtgtgt tatactttac ttggaagtgg ttgccggaaa gagcgaaaat
      361 gcctcacatt tgtgccacct aaaaaggagc gatttacata tgagttatgc agtttgtaga
      421 atgcaaaaag tgaaatcagc tggactaaaa ggcatgcaat ttcataatca aagagagcga
      481 aaaagtagaa cgaatgatga tattgaccat gagcgaacac gtgaaaatta tgatttgaa
//
LOCUS       DAFKHN010000254          533 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.270, whole genome shotgun sequence.
ACCESSION   DAFKHN010000254 DAFKHN010000000
VERSION     DAFKHN010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.270"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            120..365
                     /locus_tag="LY912_003062"
     CDS             120..365
                     /locus_tag="LY912_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956647.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
BASE COUNT          191 a           62 c           82 g          198 t
ORIGIN      
        1 agttatcaaa tttcctgtaa attttcttga aactacagca tattattact tcaaaacaat
       61 ctacattttt tataaaaaag gaaatgaata actgaaaaaa ttattatagg agagaaaaaa
      121 tgtcaaaatc taaaaaaaat atcaccataa ttggtttagg cttaaccgta tatttattta
      181 cagaatttgt ttatagacat gtgaatttat ttgcagaacc tttatttgta ttatacgaat
      241 caaattcctc aatcgtcagt gaacttgcta atttaatgat agcattgctg tttactcccg
      301 cgttgagagt cataactatt ttggtctgtt tagtgctatt gttttttgtt aataaaaaga
      361 aataacgtag tatttcaaaa gacaaagaag tgggatgatg attgctatag tatgttatac
      421 gtggtgctag gtaagtgaga ataaacaaaa aaggaaacac gcaataaagt ttatttcaaa
      481 actttattgc gtgtttcttt tttagatttt ttatatctgt tgctttagta gtt
//
LOCUS       DAFKHN010000255          491 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.271, whole genome shotgun sequence.
ACCESSION   DAFKHN010000255 DAFKHN010000000
VERSION     DAFKHN010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.271"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..359
                     /locus_tag="LY912_003063"
     CDS             <1..359
                     /locus_tag="LY912_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956648.1"
                     /translation="TLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKRKLSHGYFVSYEL
                     YEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGNICPGFMDQIIEN
                     ESIESIENYVPVDLPK"
BASE COUNT          203 a           57 c           72 g          159 t
ORIGIN      
        1 gtacattatt ttactatgag gaagttagaa atattgtaaa acatagaaaa aaagaaatgc
       61 ctatacgttg tccaaattgc aatgaagtta ttaagcgaaa gttgtctcat ggttattttg
      121 tcagctacga actatatgaa gaaagtaaaa taaatctgaa aaaaaaacca aaatactata
      181 aaaatttgaa aactggagct attataactg aaaaagaatt taaaaattta gtgactgaag
      241 aagaaagcag gttttataat ttgtctggta atatttgccc tggatttatg gatcagatta
      301 ttgaaaatga gtcaattgaa tcaattgaaa actatgttcc tgttgactta ccaaaataga
      361 aaaaataatc ctgtttttac agtgaattat tttaattttg attttcaata aaaatatatt
      421 acaataataa tcgtaatagc taatgaaaca atttctcaat ctttttacca ctccaaacag
      481 ggagcgtcaa t
//
LOCUS       DAFKHN010000256          489 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.272, whole genome shotgun sequence.
ACCESSION   DAFKHN010000256 DAFKHN010000000
VERSION     DAFKHN010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.272"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            7..>489
                     /locus_tag="LY912_003064"
     CDS             7..>489
                     /locus_tag="LY912_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956649.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     G"
BASE COUNT          181 a           66 c          100 g          142 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggg
//
LOCUS       DAFKHN010000257          485 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.273, whole genome shotgun sequence.
ACCESSION   DAFKHN010000257 DAFKHN010000000
VERSION     DAFKHN010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.273"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..>485
                     /locus_tag="LY912_003065"
     CDS             <1..>485
                     /locus_tag="LY912_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956650.1"
                     /translation="NINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKW
                     AKSNETYSQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKRED
                     FIETLRILKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYIN
                     S"
BASE COUNT          200 a           50 c           90 g          145 t
ORIGIN      
        1 aatattaata aaacagtgga aaagaatgga gtttataaag gtgattttca ttttcaaaat
       61 gctgagacta ttgaacgaga acatcattat ttcgatttat tagtgaatac agtggtagaa
      121 ttagcgaaat gggcaaagtc aaacgaaact tatagtcaag tacttaaaag aattatgagt
      181 caagaaactt catttatcta tgagttaagc aagtcaaatt tgaaatatac ttataatgaa
      241 gatgaacttg aaattttaga taatccagaa aattcacaat ggattaaaga gttgaagaga
      301 gaagacttta ttgagacact aagaattcta aaatcgttat ttgatttgaa attagccaaa
      361 gctaccatca tgggaattga aagagattca tattattggg aggaaattgg actatatgct
      421 ccccagattg aaggtgaaga taaagagaaa aggatagaca acattattaa ctatattaat
      481 agttt
//
LOCUS       DAFKHN010000258          472 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.274, whole genome shotgun sequence.
ACCESSION   DAFKHN010000258 DAFKHN010000000
VERSION     DAFKHN010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.274"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            69..>472
                     /locus_tag="LY912_003066"
     CDS             69..>472
                     /locus_tag="LY912_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956651.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANS"
BASE COUNT          182 a           47 c           91 g          152 t
ORIGIN      
        1 atgagttttt ttcgattttt caagttatct aatgcaatta tattgatatc attaggagct
       61 gcattgttat gaatccaaca ttgattacta agaaagaatt actaaaaaaa ttagatattt
      121 ctactggtgt attagctaat ttaattagaa atggcatgcc aaaagaggga gaaatgttta
      181 atcttgataa gattattaca tggcgagaaa attggtctaa aaacatatta ggtgagttag
      241 aagttggtag agtatatact aacaaagaaa tttcagagaa gtttaaatgt tccaaacagg
      301 gtggaatgag aagatctcat caaactaata ctcttgtact gtttagtgat caaacaggaa
      361 gtaatgttta taaagataag tggttaaatg gtattttaca atataccggt atggggctaa
      421 aaggggatca agtattggat aagaatcaaa ataaagtttt agccaattca aa
//
LOCUS       DAFKHN010000259          463 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.276, whole genome shotgun sequence.
ACCESSION   DAFKHN010000259 DAFKHN010000000
VERSION     DAFKHN010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.276"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..231)
                     /locus_tag="LY912_003067"
     CDS             complement(<1..231)
                     /locus_tag="LY912_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBM6956652.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQS"
BASE COUNT          167 a           62 c           51 g          183 t
ORIGIN      
        1 actttgtata attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg
       61 ttcggaagcc tgatcaatta atattgggat actagctgat aagactattt ttataatatt
      121 tccgatacca attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga
      181 atcaatagat tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa
      241 atcattaaca aaaatattat aataggattt aagtaagttc taactaatca catataaaaa
      301 taaaaaaaca tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatccta
      361 aaatataagc tatttgttta cttctgtaga atatatactt tgttgttaga taagttgcac
      421 atgtttatag aatctaaata ataaattttt atgtaccgcc cct
//
LOCUS       DAFKHN010000260          462 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.277, whole genome shotgun sequence.
ACCESSION   DAFKHN010000260 DAFKHN010000000
VERSION     DAFKHN010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.277"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..430)
                     /locus_tag="LY912_003068"
     CDS             complement(<1..430)
                     /locus_tag="LY912_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBM6956653.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DAFKHN010000261          459 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.278, whole genome shotgun sequence.
ACCESSION   DAFKHN010000261 DAFKHN010000000
VERSION     DAFKHN010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.278"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..>459
                     /locus_tag="LY912_003069"
     CDS             <1..>459
                     /locus_tag="LY912_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBM6956654.1"
                     /translation="TSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQP
                     ITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYT
                     WKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          187 a           68 c          106 g           98 t
ORIGIN      
        1 aacaagtatt gaaagtggaa caacagtctt tgcagtgaaa gacggcgtaa gcttaccaga
       61 agataaactt ccagtgttga aagcaaaaga tggttataca gatgcgaaat ggccagagga
      121 agcaactcaa ccaattacag cagatgatac agaatttgta tcaagtgcaa caaaactgga
      181 tgataaatct gacgctgaca aatataatcc tgaaggtcaa aaagtgacta cagaattgaa
      241 taaggaacca gacgcatttg agggaattaa gaacaaagaa gatttaccaa aagatactaa
      301 gtatacttgg aaagaaaaag tagatgttag cgcagctgga aataaaaaag ggactgttgt
      361 agtgacatat ccagatggat catctgatga agttgaagta gatgttacag tgacagacaa
      421 tcgttctgac gccgataaat atgagccaac agtagaagg
//
LOCUS       DAFKHN010000262          456 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.279, whole genome shotgun sequence.
ACCESSION   DAFKHN010000262 DAFKHN010000000
VERSION     DAFKHN010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.279"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(<1..441)
                     /locus_tag="LY912_003070"
     CDS             complement(<1..441)
                     /locus_tag="LY912_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HBM6956655.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFN"
BASE COUNT          134 a           92 c           58 g          172 t
ORIGIN      
        1 attgaatatc tgtttaatat aatttggtga taatggttgc tcaatgccct tttttacaac
       61 atggattttc gataaaaact gttgaaattc ctgtatatga attggtcgaa tctttacaac
      121 ctgcatttct ccaaaaaaat ccaatgcacg ttgtaaaata tgatctgttt tcatatatgt
      181 tttttctaca gttcccaact tataccaagg aaaaaaatac tctcgataaa aatcatgaaa
      241 cgttattcct tgcagataaa ttccttgtga atcagaaaaa ctttgtttta actcttcgag
      301 tccccttcta gcttctcctt gagttttgaa gcctcttctg gtcacttgaa ttctttttcc
      361 aaagcgatct tgtcctaaag ttgcagaaaa aaaccaagtg cctctttttc tgtctttata
      421 aacattcgca attttcctca ttttactatt cctccc
//
LOCUS       DAFKHN010000263          455 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.280, whole genome shotgun sequence.
ACCESSION   DAFKHN010000263 DAFKHN010000000
VERSION     DAFKHN010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.280"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(28..426)
                     /gene="spxA"
                     /locus_tag="LY912_003071"
     CDS             complement(28..426)
                     /gene="spxA"
                     /locus_tag="LY912_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBM6956656.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNFFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          129 a           93 c           82 g          151 t
ORIGIN      
        1 gtcttttcca agtttcgtat tatccttcta taatccagcc atcaattgtg cttgacgtaa
       61 ttctaattgt cgtacatcgc gcggtaggaa ccgacgaatt tcatcttcat taaaaccaac
      121 ttgcagacgt ttatcatcaa tcatgattgg acggcgaagc aatccaggat tgttttgcac
      181 aagttccaat aattcttgta acggcagatc atctaaatcc atgttcagtt tttggaatac
      241 tttggaacgt gtcgagatga tttcttctgt tccgtcttct gtcatttgta aaatcgcttt
      301 taattcagaa ctgttcaatg gttctgaaaa aaaattacgt tcaacaaatg gaatctgatg
      361 ttcttgcaac cacgcacgag cctttctgca ggaagtacaa cttggggaag tatataatgt
      421 taacaacgtg caccactcct tttcgtgata agaat
//
LOCUS       DAFKHN010000264          435 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.283, whole genome shotgun sequence.
ACCESSION   DAFKHN010000264 DAFKHN010000000
VERSION     DAFKHN010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.283"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..>435
                     /locus_tag="LY912_003072"
     CDS             <1..>435
                     /locus_tag="LY912_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBM6956657.1"
                     /translation="NLVTAARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSG
                     LVERFNENVNDYNELLEENKSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVF
                     KGFVDKVKDKTAQFQEKHDLEPKKNEFELTHNREVKKERSRD"
BASE COUNT          187 a           52 c           91 g          105 t
ORIGIN      
        1 aaaacttagt gactgctgcg agagataacg ataggttaaa acagcatgtt agaaatctca
       61 tgagtactga tatggcgaga gaatataaaa aattaagtaa agaacatggg caagttaaag
      121 aaaaatatag tggtcttgta gagcgattta atgaaaatgt aaatgattat aatgagttgc
      181 ttgaagaaaa caagtcttta aagtctaaaa taagcgattt aaagcgtgat gtgagtttaa
      241 tctatgaaag cactaaggaa ttccttaagg aacgtacaga cggcttaaaa gcctttaaaa
      301 acgtttttaa ggggtttgta gacaaggtaa aggataaaac agcacaattc caagaaaaac
      361 acgatttaga acctaaaaag aacgaatttg aactaactca taaccgagag gtaaaaaaag
      421 aacgaagtcg agatc
//
LOCUS       DAFKHN010000265          433 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.284, whole genome shotgun sequence.
ACCESSION   DAFKHN010000265 DAFKHN010000000
VERSION     DAFKHN010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.284"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
BASE COUNT          149 a           60 c           71 g          153 t
ORIGIN      
        1 tttataagtt aaaatattat gataaaaatc acaaacgtag ccttttacgt cataagtgtt
       61 aaaagaaata attaatttca aatatagaaa agggaacgta tgtttgcata ctcctttttt
      121 ttgagttata ataatacgcg aagagagata atttcattat ttaaacaagc taaaaatctt
      181 gatattactt cttttcaggc aatacgaata ttattcgctt acattttttg tataaattta
      241 attgtctgct atgcttgtga tgaattgatt ttcgttttgc acttttggat gataaatttg
      301 gacaattgaa aatacaaaaa aaagaaaggc ggtatgaact cggaaggctg gtaaccttcg
      361 tcagcgttca tacacggcat taagatttgg cccttaatgc gttaaccttt cagtgttacg
      421 gtattacccg caa
//
LOCUS       DAFKHN010000266          423 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.denovo.286, whole genome shotgun sequence.
ACCESSION   DAFKHN010000266 DAFKHN010000000
VERSION     DAFKHN010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.denovo.286"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..421
                     /locus_tag="LY912_003073"
     CDS             <1..421
                     /locus_tag="LY912_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956658.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT          158 a           65 c           86 g          114 t
ORIGIN      
        1 atcactagat cgtttaggaa gagattatga agatataaaa aatacagttg cttttatgaa
       61 acagaaaaaa gtagcgttaa aaatattaga tgcacagttt ttagatttta atactggaaa
      121 tgaactcctg gataccgcta tgttcgatat gtttttatca ctgctaagtt atattgcaca
      181 aaacgagcgt gagaaaattc gtgaacgtca gcggcaagga gtattattgg ctcaaaaagc
      241 cggccgatat aagggacgac caatcgagta ttctattaac tcaacagatc cgcaaaaacg
      301 cttagttttt aaaaccgtgg tggacatgtt aaagcaaggc attccagttg cagagattgc
      361 aaaagaaaac gggatctctc gaccaactat ttataaaata aagaaagcga atgatttgta
      421 gaa
//
LOCUS       DAFKHN010000267         4767 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.140, whole genome shotgun sequence.
ACCESSION   DAFKHN010000267 DAFKHN010000000
VERSION     DAFKHN010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.140"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1046
                     /locus_tag="LY912_003074"
     CDS             <1..1046
                     /locus_tag="LY912_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBM6956659.1"
                     /translation="WEDRKGRKINVPIADGGENTAEAIYYALGGTWRTIDGMDLLFRQ
                     RKISYLLTNWQGKNTAVIESAQVLGLDLLDKPTDQTIRLASSYALGELIKDTLLQEVE
                     QIIVTLGGSGCSDGGLGLLQSLGASLEGYTEGNPLLSTRKLHLDRRNVLVSKVKVIIA
                     ADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLDKQAEKIAQQIKDVWEVDLDDIPGSGA
                     AGGIGGALFLLGAKMVSGFELVSQITGLEKQIEQADVIITGEGRIDQQTIHGKVPYGV
                     AVLAKKYRKPIIAICGSRDRELEGLFDFLPIVLSIQLGPIDLEEAMEHRQTLEKTEIL
                     GQTLSRFFNILPK"
     gene            1304..2806
                     /gene="eat(A)"
                     /locus_tag="LY912_003075"
     CDS             1304..2806
                     /gene="eat(A)"
                     /locus_tag="LY912_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBM6956660.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            2834..3400
                     /locus_tag="LY912_003076"
     CDS             2834..3400
                     /locus_tag="LY912_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBM6956661.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            3612..4673
                     /locus_tag="LY912_003077"
     CDS             3612..4673
                     /locus_tag="LY912_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBM6956662.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4676..>4767
                     /gene="murQ"
                     /locus_tag="LY912_003078"
                     /gene_synonym="yfeU"
     CDS             4676..>4767
                     /gene="murQ"
                     /locus_tag="LY912_003078"
                     /gene_synonym="yfeU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="catalyzes the cleavage of the lactyl ether moiety
                     of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form
                     N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate;
                     involved in MurNAc dissimilation pathway; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBM6956663.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAV"
BASE COUNT         1630 a          818 c         1068 g         1251 t
ORIGIN      
        1 gttgggaaga ccgtaaagga agaaaaatca atgtgccgat tgcagatggc ggagaaaata
       61 ctgcagaagc aatctattac gcgctcgggg gaacctggcg tacgattgat gggatggatc
      121 tcttatttcg tcagcgaaaa atcagttatt tattgacgaa ctggcaagga aaaaataccg
      181 cagtcattga atctgcacaa gtattaggat tagatttact tgataaacca acggatcaaa
      241 ccatccgact tgcttctagt tatgccttgg gagagcttat caaagataca ctgcttcaag
      301 aagtggaaca aatcattgtc actttaggag gaagcggatg tagcgatggt ggtctaggat
      361 tactccaatc tttgggtgct tctttagaag ggtacacaga aggaaatcct ttgttatcta
      421 ctagaaaact tcatttggat cgaaggaacg ttcttgtttc taaagtaaaa gtgatcatcg
      481 ctgcagacgt gaccaaccca tatacaggtc aacaaggagc tgcttggcaa tttggaagac
      541 aaaaaggagg aacggatacg acgttagctt tcttggataa acaagctgaa aagattgctc
      601 agcagataaa agatgtttgg gaggtggatt tagatgacat cccaggaagc ggagcagcag
      661 gcggtattgg cggagccctt tttttgttag gagcgaagat ggtctctggt tttgagttgg
      721 tcagccaaat cactggatta gaaaaacaga tcgaacaagc ggatgtcatc attacaggag
      781 aagggcggat tgatcagcaa acaatccacg gaaaagttcc atatggcgta gcagtgcttg
      841 caaaaaaata tcgaaaacca ataatcgcta tttgcggaag tagagaccga gagctggaag
      901 gactctttga ttttctcccc attgtcttaa gcattcaatt aggaccaatc gatttagagg
      961 aagcaatgga acacaggcaa acattagaaa aaacagaaat cttaggacag acactcagca
     1021 gatttttcaa cattctcccg aagtagttga caaaaacaat ttctttatgc tatcgtaatt
     1081 tcaaatatag gacaaagtga gggatccgtg cattgaaaaa ttaagtcgat tgatgaaagc
     1141 tgcattcaga ctgtaccttg tggagacaag ggagcagtgt gcagattttc gggattggct
     1201 tggttctttc gatgtatggg tctttttgtg tgccccaacc cttgcatcct ctttagccag
     1261 ttctgaaaat aggactggtc tttttttacg aggtgatgga ataatgtcta aaatcgaaat
     1321 aaaaaatctg acattcggct atgacagcca aggcacatta ttatttgaac aagccaatct
     1381 aaactttgac acacaatgga aactaggact tatcggacga aacggtcgag gaaagacaac
     1441 tttactgaat atcctgcaaa acaaactccc ttatcaaggg caagtgatcc atcagcaagc
     1501 gtttgtctat ttcccgcagc aaacaaaaga taaagagcgt ttgacctatt atgtgttaaa
     1561 tgagattatg gattttgaga tatgggaaat tgaaagagag ctccaactga tgcaaacaga
     1621 tcctgaaatc ttatggagag aattcagcac actatcagga ggagagaaga caaaagtcct
     1681 actggcactc ttatttgtgg atgacactca tttcccgtta atcgatgaac caacgaatca
     1741 tttggatatc tctggcagaa aacaagtagc ggcttacttg aaaaagaaaa aacaaggatt
     1801 catcgtggtg agtcatgatc ggggatttat cgatgaagta gtggaccatg ttttagcaat
     1861 cgaaaagagc caactggaac tttatcaagg gaatttctct atctatgaag aacagaaaaa
     1921 acttcgtgat gaatttgaaa tagctaaaaa tgaaaaattg aaaaaagaag tcagcaggct
     1981 aaagaaaaca gcagctgaaa aagcagaatg gtctcgttcc cgagaagggg acaaaacaaa
     2041 gaaaaaagtc ggattcatcg atacggaatc taggcgagtg aataaaggag cagtaggcgc
     2101 tgatgctgca cggacgatga aacgatctaa agcaatcgtg aatcggatgg aaacccagat
     2161 cagtgagaaa gaaaaattat taaaagatat cgagtatatc gatgctttga cgatgaatag
     2221 ccaagtgtct catcataaac ggctgttaag cgtagaaaat cttcaattag ggtatgaaaa
     2281 tctgttattc gagccagttc attttacgat cgaacctcat cagcggatgg caatttcagg
     2341 tcctaacggc gcgggaaagt catccattat ccattatctt ctggggacat tcaacggcaa
     2401 ggttgtagga gaaaaatccc agcccaaaca tttgaccatt agttacgtac gccaaaatta
     2461 tgaagacaat cgagggacat tggcggaatt cgcgaagaaa aaccgagtag actatcaagc
     2521 atttttgaat aatctccgaa agcttgggat ggaaagagat gtttttcata ataaaatcga
     2581 acagatgagt atgggacaac ggaaaaaagt ggaattggct aaatctttat cccaaccagc
     2641 tgagctctat atatgggatg aaccattgaa ttatttggat gtcttcaatc aagaacaatt
     2701 agaacaactg attttgaacg tgaaacctgc tatgttacta gtggaacatg atcaaacctt
     2761 tctagataaa gtatctactg agattatttc tcttgagaaa atctaaacct tgtaatctca
     2821 aagacaacaa ggtatggtta aggagaactt tgtcaacgaa ggagagaatc acatgcttta
     2881 tgtaacgaga cacggagaaa caacttggaa cgcacaagga ttagtttgcg ggcgagcaga
     2941 tgtgccgctg actgaaaaag gacagatgca ggcacaggca ctagcagaaa aggtagtaga
     3001 tttgcctgtt ccaatcacga aaatcatcca ttcccctctt caacgagcaa gagatacagc
     3061 acaagcagta gttgatcgtc tcaatttgcc gatgaccgct gatgagcgat tggtagaaat
     3121 ggattttggg gattatgacg gactgccaag caaagatgaa aactttcaaa aagcgcgttt
     3181 agcgtttgct gtacgtttcc caaatggaga gtcggtctta gatgtgtacg cacggatcgt
     3241 tcctttattg aaagaatgca tggaagacga agaaaatgtc tacttgttag tctgtcataa
     3301 tgccttgata agagtgatca atgcttattt tcatccaatg cctaatgaag ggttctttac
     3361 attcatggta gacaatacag aattaatttc ttatgagtaa ttagactttt gtgttattta
     3421 aataaaatgt ttcaaggcac tgcttttgct tagcagtgcc ttttttgtgg ctgtgtcaat
     3481 tcttttggca ttataaatcc aatttttaga aataaaattt aattatttta acaaaagtat
     3541 tgaaattttg tttctttaga tatatactct agtcatagaa atgaagacgg atacagaaaa
     3601 agagggataa tatgtttggc ttttcaatat ttatgaatga ttctttgtca gaagagaaga
     3661 aacagtatat ccgccaaatg gcatccaatg gctttgtcgg tattttcact tccatgcata
     3721 taccggaaga tgatgtttcg gcttatcaaa atcgattgat cgaactagga agcgaagcga
     3781 aaaagaataa actagagttg atggtcgata tttcaggaga ggcattgaaa cgagctggct
     3841 tttcattaga agatctaaca cccttgaaag caattggtgt aacagggtta agaatggatt
     3901 atcatatttc taatcagcag atcgccgact ggtcacatca attgaaaatc agtttgaatg
     3961 ccagcacgat cacgcctaat gatatcgatg agttgaaaga agcagcggct gatttctcac
     4021 agattgaagc ttggcataat tattatccac gtcttgaaac agggttggac aaagaatggt
     4081 atcaggaaaa aaatcaatgg ctcaaaactc aaggattcct tgtacaaggc tttgtaccag
     4141 gagatacaga gttgagaggt ccactgtatc aaggattacc aactttggaa gaacatcgag
     4201 ggatccatcc tctggcaggt gctcttgatc tattagcaag taacacggat attgtttata
     4261 tcggagatgc aggtctgtca gaacacgttc aggagcaatt tgcttctttc caaaaagaac
     4321 agacagtctt gctccatacg gaacctgtag atgaagtttt ttacgaatat atattaggaa
     4381 aacatacgaa tcggcaagat gatgcaagag atgtcatacg aagcgcagat gcgcgttttc
     4441 gagagattcc gccaatccca gtaagaaata cagctaagcg tatgaaagga tctattactt
     4501 tagataacga aaagtatttg cgctatatgg gtgagatcca attaactaaa tatgatttgc
     4561 cagcggatga aaaagtgaat gtagtagcca aagtcatcaa agaagaacta ccgctgatca
     4621 accaaatcaa agctggtatg aactatcaat ttataagaaa agaaggaaga taaaaatgag
     4681 caaaatcaat ttagagaacc taacaacgga acgcagaaac caagaaactt ttggattaga
     4741 tgaaatgagt atttctcaag cagtcca
//
LOCUS       DAFKHN010000268         4767 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.141, whole genome shotgun sequence.
ACCESSION   DAFKHN010000268 DAFKHN010000000
VERSION     DAFKHN010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.141"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..1046
                     /locus_tag="LY912_003079"
     CDS             <1..1046
                     /locus_tag="LY912_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBM6956664.1"
                     /translation="WEDRKGRKINVPIADGGENTAEAIYYALGGTWRTIDGMDLLFRQ
                     RKISYLLTNWQGKNTAVIESAQVLGLDLLDKPTDQTIRLASSYALGELIKDTLLQEVE
                     QIIVTLGGSGCSDGGLGLLQSLGASLEGYTEGNPLLSTRKLHLDRRNVLVSKVKVIIA
                     ADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLDKQAEKIAQQIKDVWEVDLDDIPGSGA
                     AGGIGGALFLLGAKMVSGFELVSQITGLEKQIEQADVIITGEGRIDQQTIHGKVPYGV
                     AVLAKKYRKPIIAICGSRDRELEGLFDFLPIVLSIQLGPIDLEEAMEHRQTLEKTEIL
                     GQTLSRFFNILPK"
     gene            1304..2806
                     /gene="eat(A)"
                     /locus_tag="LY912_003080"
     CDS             1304..2806
                     /gene="eat(A)"
                     /locus_tag="LY912_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBM6956665.1"
                     /translation="MSKIEIKNLTFGYDIQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            2834..3400
                     /locus_tag="LY912_003081"
     CDS             2834..3400
                     /locus_tag="LY912_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBM6956666.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            3612..4673
                     /locus_tag="LY912_003082"
     CDS             3612..4673
                     /locus_tag="LY912_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBM6956667.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4676..>4767
                     /gene="murQ"
                     /locus_tag="LY912_003083"
                     /gene_synonym="yfeU"
     CDS             4676..>4767
                     /gene="murQ"
                     /locus_tag="LY912_003083"
                     /gene_synonym="yfeU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="catalyzes the cleavage of the lactyl ether moiety
                     of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form
                     N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate;
                     involved in MurNAc dissimilation pathway; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBM6956668.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAV"
BASE COUNT         1630 a          818 c         1067 g         1252 t
ORIGIN      
        1 gttgggaaga ccgtaaagga agaaaaatca atgtgccgat tgcagatggc ggagaaaata
       61 ctgcagaagc aatctattac gcgctcgggg gaacctggcg tacgattgat gggatggatc
      121 tcttatttcg tcagcgaaaa atcagttatt tattgacgaa ctggcaagga aaaaataccg
      181 cagtcattga atctgcacaa gtattaggat tagatttact tgataaacca acggatcaaa
      241 ccatccgact tgcttctagt tatgccttgg gagagcttat caaagataca ctgcttcaag
      301 aagtggaaca aatcattgtc actttaggag gaagcggatg tagcgatggt ggtctaggat
      361 tactccaatc tttgggtgct tctttagaag ggtacacaga aggaaatcct ttgttatcta
      421 ctagaaaact tcatttggat cgaaggaacg ttcttgtttc taaagtaaaa gtgatcatcg
      481 ctgcagacgt gaccaaccca tatacaggtc aacaaggagc tgcttggcaa tttggaagac
      541 aaaaaggagg aacggatacg acgttagctt tcttggataa acaagctgaa aagattgctc
      601 agcagataaa agatgtttgg gaggtggatt tagatgacat cccaggaagc ggagcagcag
      661 gcggtattgg cggagccctt tttttgttag gagcgaagat ggtctctggt tttgagttgg
      721 tcagccaaat cactggatta gaaaaacaga tcgaacaagc ggatgtcatc attacaggag
      781 aagggcggat tgatcagcaa acaatccacg gaaaagttcc atatggcgta gcagtgcttg
      841 caaaaaaata tcgaaaacca ataatcgcta tttgcggaag tagagaccga gagctggaag
      901 gactctttga ttttctcccc attgtcttaa gcattcaatt aggaccaatc gatttagagg
      961 aagcaatgga acacaggcaa acattagaaa aaacagaaat cttaggacag acactcagca
     1021 gatttttcaa cattctcccg aagtagttga caaaaacaat ttctttatgc tatcgtaatt
     1081 tcaaatatag gacaaagtga gggatccgtg cattgaaaaa ttaagtcgat tgatgaaagc
     1141 tgcattcaga ctgtaccttg tggagacaag ggagcagtgt gcagattttc gggattggct
     1201 tggttctttc gatgtatggg tctttttgtg tgccccaacc cttgcatcct ctttagccag
     1261 ttctgaaaat aggactggtc tttttttacg aggtgatgga ataatgtcta aaatcgaaat
     1321 aaaaaatctg acattcggct atgacatcca aggcacatta ttatttgaac aagccaatct
     1381 aaactttgac acacaatgga aactaggact tatcggacga aacggtcgag gaaagacaac
     1441 tttactgaat atcctgcaaa acaaactccc ttatcaaggg caagtgatcc atcagcaagc
     1501 gtttgtctat ttcccgcagc aaacaaaaga taaagagcgt ttgacctatt atgtgttaaa
     1561 tgagattatg gattttgaga tatgggaaat tgaaagagag ctccaactga tgcaaacaga
     1621 tcctgaaatc ttatggagag aattcagcac actatcagga ggagagaaga caaaagtcct
     1681 actggcactc ttatttgtgg atgacactca tttcccgtta atcgatgaac caacgaatca
     1741 tttggatatc tctggcagaa aacaagtagc ggcttacttg aaaaagaaaa aacaaggatt
     1801 catcgtggtg agtcatgatc ggggatttat cgatgaagta gtggaccatg ttttagcaat
     1861 cgaaaagagc caactggaac tttatcaagg gaatttctct atctatgaag aacagaaaaa
     1921 acttcgtgat gaatttgaaa tagctaaaaa tgaaaaattg aaaaaagaag tcagcaggct
     1981 aaagaaaaca gcagctgaaa aagcagaatg gtctcgttcc cgagaagggg acaaaacaaa
     2041 gaaaaaagtc ggattcatcg atacggaatc taggcgagtg aataaaggag cagtaggcgc
     2101 tgatgctgca cggacgatga aacgatctaa agcaatcgtg aatcggatgg aaacccagat
     2161 cagtgagaaa gaaaaattat taaaagatat cgagtatatc gatgctttga cgatgaatag
     2221 ccaagtgtct catcataaac ggctgttaag cgtagaaaat cttcaattag ggtatgaaaa
     2281 tctgttattc gagccagttc attttacgat cgaacctcat cagcggatgg caatttcagg
     2341 tcctaacggc gcgggaaagt catccattat ccattatctt ctggggacat tcaacggcaa
     2401 ggttgtagga gaaaaatccc agcccaaaca tttgaccatt agttacgtac gccaaaatta
     2461 tgaagacaat cgagggacat tggcggaatt cgcgaagaaa aaccgagtag actatcaagc
     2521 atttttgaat aatctccgaa agcttgggat ggaaagagat gtttttcata ataaaatcga
     2581 acagatgagt atgggacaac ggaaaaaagt ggaattggct aaatctttat cccaaccagc
     2641 tgagctctat atatgggatg aaccattgaa ttatttggat gtcttcaatc aagaacaatt
     2701 agaacaactg attttgaacg tgaaacctgc tatgttacta gtggaacatg atcaaacctt
     2761 tctagataaa gtatctactg agattatttc tcttgagaaa atctaaacct tgtaatctca
     2821 aagacaacaa ggtatggtta aggagaactt tgtcaacgaa ggagagaatc acatgcttta
     2881 tgtaacgaga cacggagaaa caacttggaa cgcacaagga ttagtttgcg ggcgagcaga
     2941 tgtgccgctg actgaaaaag gacagatgca ggcacaggca ctagcagaaa aggtagtaga
     3001 tttgcctgtt ccaatcacga aaatcatcca ttcccctctt caacgagcaa gagatacagc
     3061 acaagcagta gttgatcgtc tcaatttgcc gatgaccgct gatgagcgat tggtagaaat
     3121 ggattttggg gattatgacg gactgccaag caaagatgaa aactttcaaa aagcgcgttt
     3181 agcgtttgct gtacgtttcc caaatggaga gtcggtctta gatgtgtacg cacggatcgt
     3241 tcctttattg aaagaatgca tggaagacga agaaaatgtc tacttgttag tctgtcataa
     3301 tgccttgata agagtgatca atgcttattt tcatccaatg cctaatgaag ggttctttac
     3361 attcatggta gacaatacag aattaatttc ttatgagtaa ttagactttt gtgttattta
     3421 aataaaatgt ttcaaggcac tgcttttgct tagcagtgcc ttttttgtgg ctgtgtcaat
     3481 tcttttggca ttataaatcc aatttttaga aataaaattt aattatttta acaaaagtat
     3541 tgaaattttg tttctttaga tatatactct agtcatagaa atgaagacgg atacagaaaa
     3601 agagggataa tatgtttggc ttttcaatat ttatgaatga ttctttgtca gaagagaaga
     3661 aacagtatat ccgccaaatg gcatccaatg gctttgtcgg tattttcact tccatgcata
     3721 taccggaaga tgatgtttcg gcttatcaaa atcgattgat cgaactagga agcgaagcga
     3781 aaaagaataa actagagttg atggtcgata tttcaggaga ggcattgaaa cgagctggct
     3841 tttcattaga agatctaaca cccttgaaag caattggtgt aacagggtta agaatggatt
     3901 atcatatttc taatcagcag atcgccgact ggtcacatca attgaaaatc agtttgaatg
     3961 ccagcacgat cacgcctaat gatatcgatg agttgaaaga agcagcggct gatttctcac
     4021 agattgaagc ttggcataat tattatccac gtcttgaaac agggttggac aaagaatggt
     4081 atcaggaaaa aaatcaatgg ctcaaaactc aaggattcct tgtacaaggc tttgtaccag
     4141 gagatacaga gttgagaggt ccactgtatc aaggattacc aactttggaa gaacatcgag
     4201 ggatccatcc tctggcaggt gctcttgatc tattagcaag taacacggat attgtttata
     4261 tcggagatgc aggtctgtca gaacacgttc aggagcaatt tgcttctttc caaaaagaac
     4321 agacagtctt gctccatacg gaacctgtag atgaagtttt ttacgaatat atattaggaa
     4381 aacatacgaa tcggcaagat gatgcaagag atgtcatacg aagcgcagat gcgcgttttc
     4441 gagagattcc gccaatccca gtaagaaata cagctaagcg tatgaaagga tctattactt
     4501 tagataacga aaagtatttg cgctatatgg gtgagatcca attaactaaa tatgatttgc
     4561 cagcggatga aaaagtgaat gtagtagcca aagtcatcaa agaagaacta ccgctgatca
     4621 accaaatcaa agctggtatg aactatcaat ttataagaaa agaaggaaga taaaaatgag
     4681 caaaatcaat ttagagaacc taacaacgga acgcagaaac caagaaactt ttggattaga
     4741 tgaaatgagt atttctcaag cagtcca
//
LOCUS       DAFKHN010000269         4470 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.145, whole genome shotgun sequence.
ACCESSION   DAFKHN010000269 DAFKHN010000000
VERSION     DAFKHN010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.145"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..698
                     /locus_tag="LY912_003084"
     CDS             <1..698
                     /locus_tag="LY912_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBM6956669.1"
                     /translation="TTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGW
                     FGFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLA
                     AITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILI
                     GIFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQE
                     EGLDFFFFGNKLN"
     gene            729..947
                     /locus_tag="LY912_003085"
                     /pseudo
     CDS             729..947
                     /locus_tag="LY912_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1366..1839
                     /gene="dfrF"
                     /locus_tag="LY912_003086"
     CDS             1366..1839
                     /gene="dfrF"
                     /locus_tag="LY912_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBM6956670.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            1966..2622
                     /locus_tag="LY912_003087"
     CDS             1966..2622
                     /locus_tag="LY912_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBM6956671.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            2804..3334
                     /locus_tag="LY912_003088"
     CDS             2804..3334
                     /locus_tag="LY912_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBM6956672.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFAK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            3880..4122
                     /locus_tag="LY912_003089"
     CDS             3880..4122
                     /locus_tag="LY912_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBM6956673.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            4119..>4470
                     /locus_tag="LY912_003090"
     CDS             4119..>4470
                     /locus_tag="LY912_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBM6956674.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEII"
BASE COUNT         1552 a          619 c          946 g         1353 t
ORIGIN      
        1 acacgacagc tggattcggc tctttagcat gtatcctcac acttggtcaa agaaagattc
       61 ctttaggaga aagaagtcag catagcagtc ttatggcagc tgctatcggt acaggactgc
      121 tttggtttgg ctggttcggt tttaattccg gtggtgcact tcgagcagat gaacaagcag
      181 tcaatgcatt tggttcaaca ttcatcgctc ttgcatttgc gatgattact tggctgatca
      241 ttgcaaaagt aaaaggaaat ggctttgatt ttgtcgacgt actaacagga tccgttgctg
      301 gattggcagc cattacgcct tgtgccggtt atgtagaagc aaaaagtgcc atgctgattg
      361 ggatcattgc gggtatcgtc tgtcatgctg ctgttgattt tcgtaaaaag aaacaatggg
      421 atgatgcact tgatgtgtgg ggtgttcatg gcatgggcgg attcacaggt acgattctga
      481 tagggatctt tgcatctaac agccatttac taacgaatcc aagcagctgg tacttcttag
      541 ggattcaagt gattggtgtc atcattactg ccgtgtatgc ctatgtgctg acaacagtga
      601 ttttaaaatc ggcgatgcac tttacaacga tcactactac aaaagaagaa caagaagaag
      661 gattggactt tttcttcttt ggcaacaaac tcaattgaaa caaattcaaa tagaaaagag
      721 gaagattcat gcaacaaagc aaaacgaaaa ttcctgcaaa aaaattaacg ttctttggct
      781 ttttggctat gaccatctca atggtcgttt cattatatga atatcccaca ttcgcgacct
      841 caggcttcag cttagtattt ttcttgttat taggcggttt gctatggttt atccctgtgg
      901 cattgtgcgc agcagagatg gcaacggtga aaggatggga aaaaggtgtt tcccaaacaa
      961 aaagatatta agaaacagcc catgtttacc tgcttgcaaa caaaagaata ttgctactag
     1021 actaagagat actacataag tgtgttggta tctctttttt gttgccgtga aacagcagac
     1081 tatttcattt ctgcttgatt accttaaaac ttattagtct atggtttgtc aagggcttgt
     1141 tgcgtgagaa atgctgaata tcacccttta caaaacatag gctgataagt aacttttcaa
     1201 aagcagaaaa gaaatggcaa tgcttataac aatatgatat aatgcagatg aagacaaaaa
     1261 aggaatttgt cgagctggtt agttcgagat aattttgagt ttgttaagat gtggtgcact
     1321 tgatggaatc acaggtacga catcatatta tggaggatga aatagatgat aggtttgatt
     1381 gttgcgaggt caaagaataa tgttataggc aagaatggta atataccatg gaaaataaag
     1441 ggagaacaaa agcaatttag agagttaaca acgggtaatg tggttattat ggggcgaaag
     1501 tcttatgaag aaatcggtca tccgttgcct aatagaatga atattgttgt ttccaccaca
     1561 acagagtatc aaggagataa tttagtttca gttaaatcat tagaagatgc attattattg
     1621 gctaaaggac gagatgtata catatctggt ggatatggac tatttaagga agctttgcaa
     1681 atagtagata aaatgtatat cacagaagta gatttaaata ttgaagatgg agatacattc
     1741 tttccagaat ttgatatcaa tgattttgaa gttttgatag gggaaacact tggtgaggaa
     1801 gtgaaatata cgagaacatt ttatgtaagg aaaaaatgaa ttgagtaaat tttggattta
     1861 gggtgttttc ataaatatat tgctttttat gcatatataa attgttgtaa gacaaattcc
     1921 agtttgtatg gggcgataaa atcagaattt gagagaggat tgaatatgaa taaggaatgg
     1981 tctgaactta ataaaacaat gcaggcacaa ataaaaaaga aagatactta taagaggggt
     2041 attgatactt tacttacttt acgaagtcag ttaatacaaa ccttagtatc tttcaaagaa
     2101 gaattatgca gagaagattt taactcaatc cccttcataa acgctgatgg ttatcatagt
     2161 aagacgattg cttattctat ttggcatatt ttccgcattg aagatatagt tgtgcataca
     2221 gtgataaatg aagatgaaca agtatttttt gcaggcaatt atcaagagcg tatcaattca
     2281 cctatcatta caacaggaaa tgaactcatg aaacagcaga ttgcagactt ttcaaaacag
     2341 cttaatctgg aagaattata tttatatatt ttcgaagtat gggaaagcac tgagaaaatg
     2401 cttgaacggt tatcttatga tgaattgaaa agaaaaatac cgaaagaaag aaaaggatac
     2461 ttagaatcgt tgaatgtagt aaacgacaat gaaaaagcaa tttggctgat tgattattgg
     2521 tgtaataaag atatttgtgg actaattcaa atgccgtttt caagacattg gattatgcac
     2581 acagaagcct gtttgcgtat aaagaacaag atacattcat aggcaaaaat ttcagtttgt
     2641 agaactaagg aaattggaat ttaaggagga ataaagtatg gttagtgatt ttataagagc
     2701 agcatttcca tggattttaa tgggtttatt tgtagcaatc agttgttccc ttatgagtaa
     2761 aaaagagaaa taaattcctg tttgtattta taaaagagaa aaaatgagaa aagtagtttt
     2821 atttattgcc atgagccttg acggatatat tgcggacggt aatggtggag tagcttggct
     2881 aaatggtcat ggaaatgaca atgaaaacat cgacacttat acagaatttg ccaaagatat
     2941 agatactgtc ttaatggggt ggaatacttc tcatcaggtt gttactgaac tttctccgca
     3001 agaatgggta tataataaat ttacaactta tgtattaaca cataaagagt gcaattcttc
     3061 ccaacaaatt cattttacaa gtgaaaatcc tgttttatta ttggaacggc taaaacaaga
     3121 agcaggaaag gatatttgga tttgtggcgg agcaaatctt gttcagcagt tggtaagcaa
     3181 aaatatgatt gataaatatt acatttctgt tattcctact ctgttaggaa atggggttcg
     3241 tcttttgggc aacatagaca gggaaataaa gttaaggctt tgtaaaacac agacttataa
     3301 cggaataacc gatttgattt atatgcgtag ataactagag agaaacagaa aagctgttaa
     3361 accgacggag cgatccgacc acgttggcgg gaaaatcctt aagatttttc cgccatgctt
     3421 gcaagggggc ggttcgcttc ggcggttcgg cgagcttgcg agccgttcaa agcccccgtt
     3481 atctaacaag gggggcacaa aaaacaagaa acactataca ctaacaagcg gaaaacgctg
     3541 tatttataag gcaaaacccc atttttacag tagtgatata aattgtacct atatcactat
     3601 gaaaattgaa tagtaaatat gagaaagaca gttgatttca aaaaataaga aattgattgt
     3661 cgttttcttt tgcagaaatt taagtgcagg caattatggt agttgtcgta attgctgtca
     3721 gctcagtgtt tatcactgat ggtgtgaaag atttacggtt ggagatgttc aataagatta
     3781 ttggtgctta attattttta ttgtagtgct gatatgagaa tgttataatt ggggtataaa
     3841 acatacaaat aaatttgctg aaaaatgagg tatcaaaata tggaaaatga attactggaa
     3901 aacttaggaa gacttcacac aactgaactt ggcgttatta gaattaaaaa gaacttatct
     3961 ttgaatgtag aaaatgtaat tgaatggtgc aaagaaaaaa ttagcctttc taatgcggaa
     4021 atcacaagaa aaggaaaaaa ctggtatata acgattgata attgtattat aacggtaaat
     4081 gcgtacagtt ataccgttat cactgctcac aaggtaaaat gataaatttt tctataaagg
     4141 aattaaacgc atttgcagtt attgggcagg aagtagaact gactaattat caaaaaaaga
     4201 atattcagat tagtacacag ttttggagaa agtttaacag tagtttgaaa aaagcgtatc
     4261 tttcacaatc aggaaattgg gtaaaatatg cttttatgga aagaagaaat ggaaaacttt
     4321 attatttctg ttctattccc caaagaacca ttaccccaga gggctttctg tataaagaaa
     4381 taccgtctta taaatatttg gttgtggagc atattggtgc tatggataaa atatatgaaa
     4441 cttatggcaa gatttatgaa gaaattattc
//
LOCUS       DAFKHN010000270         4463 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.147, whole genome shotgun sequence.
ACCESSION   DAFKHN010000270 DAFKHN010000000
VERSION     DAFKHN010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.147"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            complement(22..1698)
                     /locus_tag="LY912_003091"
                     /pseudo
     CDS             complement(22..1698)
                     /locus_tag="LY912_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
     gene            1844..2419
                     /locus_tag="LY912_003092"
     CDS             1844..2419
                     /locus_tag="LY912_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBM6956675.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            2633..3328
                     /gene="vanR"
                     /locus_tag="LY912_003093"
     CDS             2633..3328
                     /gene="vanR"
                     /locus_tag="LY912_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBM6956676.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            3306..4457
                     /locus_tag="LY912_003094"
     CDS             3306..4457
                     /locus_tag="LY912_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBM6956677.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPGFCCKVLNKE"
BASE COUNT         1431 a          838 c          855 g         1339 t
ORIGIN      
        1 agggatttta ttctttattt aaaactttgc aacagaacct gatagctttc ctttttcaag
       61 agaaacccca tctaacttat tggaattggc agctaaccac tttaaccttt cattaaagct
      121 gctggttctc tccgttatat aatcttcgaa tgataaacta actgataatc tcgtattccc
      181 cttcgattga ttccatgtat cttccgaaaa caaatattcc tcaaaatccc tatattgtct
      241 gctgccaaca atggaaacat ctcctgcccg aacatgctcc cgaagttctg ttaaaacagc
      301 catttcatag taatgacgat taattgttgt accatcatcc tcgtataaat gtcttttcca
      361 tcgttttgaa ataaaatcca caggtgagtc atcaggcact tttcgctttc cagattcgtt
      421 cattcctcgg ataatctcaa cagcttgtaa aagtggctca tttgcctttg tagaatgaaa
      481 ttccaatact cttaatagcg ttggcgtata ttttcttagt gaataaaacc gtttttgcag
      541 taagtctaaa taatcatagt cggcaggacg tgcaagttcc tgagcctctt ctactgaaga
      601 gacaaaggta ttccattcaa taaccgattc taaaacctta aaaacgtcta atttttcctc
      661 tcttgcttta attaatgctt gtccgatgtt cgtaaagtgt ataactttct catttagctt
      721 tttaccgttt tgtttctgga tttcctcttg agccttacga ccttttgata acaaactaag
      781 tatttgccta tcatgaattt caaacgcttt atccgttagc tcctgagtaa gttgtaataa
      841 atagatggtt aatatcgaat aacgtttatt ttcttgaaag tcacggaatg catacggctc
      901 gtatcttgag cctaagcgag acagctgcaa caggcggtta cggtgcaaat gactaatttg
      961 cactgtttct aaatccattc ctcgtatgta ttcgagtcgt tctattattt ttagaaaagt
     1021 ttcgggtgaa ggatgacccg gtggctcttt taaccaaccc aatatcgttt tattggattc
     1081 ggatggatgc tgcgaggtaa taatcccttc aagcttttct ttttgctcat ttgttagaga
     1141 tttactaacc gtattaaata gcttcttttc agccattgcc cttgcttccc acaccattct
     1201 ttcaagtgta gtgatagcag gcagtataat tttgtttttt cttagaaaat ctatgcattc
     1261 atgcagtaga tgaatggcat caccattttc caaagctaat tgatgaaggt acttaaatgt
     1321 cattcgatat tcactcaggg taaaagttac aaagtcgtat tcacttcgaa tttctttcaa
     1381 atgatcccaa agtgtatttt ccctttgagg ataatgatca agcgaggatg gactaacacc
     1441 aatctgtttc gatatatatt gtatgaccga atctgggatg cttttgatat gagtgtatgg
     1501 ccaaccggga taccgaagaa cagctaattg aacagcaaat cctaaacggt tttcttccct
     1561 ccttcgctta ttaactattt ctaaatcccg tttggaaaaa gtgaagtagg tccccagtat
     1621 ccattcatct tcagggattt gcataaaagc ctgtctctgt tccggtgtaa gcaattctct
     1681 acctctcgca attttcattc agtatcattc catttctgta ttttcaattt attagttcaa
     1741 ttatatatca atagagtgta ctctattgat acaaatgtag tagactgata aaatcatagt
     1801 taagagcgtc tcataagact tgtctcaaaa atgaggtgat attttgcgga aaatcggtta
     1861 tattcgtgtc agttcgacta accagaatcc ttcaagacaa tttcagcagt tgaacgagat
     1921 cggaatggat attatatatg aagagaaagt ttcaggagca acaaaggatc gcgagcaact
     1981 tcaaaaagtg ttagacgatt tacaggaaga tgacatcatt tatgttacag acttaactcg
     2041 aatcactcgt agtacacaag atctatttga attaatcgat aacatacgag ataaaaaggc
     2101 aagtttaaaa tcactaaaag atacatggct tgatttatca gaagataatc catacagcca
     2161 attcttaatt actgtaatgg ctggtgttaa ccaattagag cgagatctta ttcggatgag
     2221 acaacgtgaa gggattgaat tggctaagaa agaaggaaag tttaaaggtc gattaaagaa
     2281 gtatcataaa aatcacgcag gaatgaatta tgcggtaaag ctatataaag aaggaaatat
     2341 gactgtaaat caaatttgtg aaattactaa tgtatctagg gcttcattat acaggaaatt
     2401 atcagaagtg aataattagc cattctgtat tccgctaatg ggcaatattt ttaaagaaga
     2461 aaaggaaact ataaaatatt aacagcctcc tagcgatgcc gaaaagccct ttgataaaaa
     2521 aagaatcatc atcttaagaa attcttagtc atttattatg taaatgctta taaattcggc
     2581 cctataatct gataaattat taagggcaaa cttatgtgaa agggtgataa ctatgagcga
     2641 taaaatactt attgtggatg atgaacatga aattgccgat ttggttgaat tatacttaaa
     2701 aaacgagaat tatacggttt tcaaatacta taccgccaaa gaagcattgg aatgtataga
     2761 caagtctgag attgaccttg ccatattgga catcatgctt cccggcacaa gcggccttac
     2821 tatctgtcaa aaaataaggg acaagcacac ctatccgatt atcatgctga ccgggaaaga
     2881 tacagaggta gataaaatta cagggttaac aatcggcgcg gatgattata taacgaagcc
     2941 ctttcgccca ctggagttaa ttgctcgggt aaaggcccag ttgcgccgat acaaaaaatt
     3001 cagtggagta aaggagcaga acgaaaatgt tatcgtccac tccggccttg tcattaatgt
     3061 taacacccat gagtgttatc tgaacgagaa gcagttatcc cttactccca ccgagttttc
     3121 aatactgcga atcctctgtg aaaacaaggg gaatgtggtt agctccgagc tgctatttca
     3181 tgagatatgg ggcgacgaat atttcagcaa gagcaacaac accatcaccg tgcatatccg
     3241 gcatttgcgc gaaaaaatga acgacaccat tgataatccg aaatatataa aaacggtatg
     3301 gggggttggt tataaaattg aaaaataaaa aaaacgacta ttccaaacta gaacgaaaac
     3361 tttacatgta tatcgttgca attgttgtgg tagcaattgt attcgtgttg tatattcgtt
     3421 caatgatccg agggaaactt ggggattgga tcttaagtat tttggaaaac aaatatgact
     3481 taaatcacct ggacgcgatg aaattatatc aatattccat acggaacaat atagatatct
     3541 ttatttatgt ggcgattgtc attagtattc ttattctatg tcgcgtcatg ctttcaaaat
     3601 tcgcaaaata ctttgacgag ataaataccg gcattgatgt acttattcag aacgaagata
     3661 aacaaattga gctttctgcg gaaatggatg ttatggaaca aaagctcaac acattaaaac
     3721 ggactctgga aaagcgagag caggatgcaa agctggccga acaaagaaaa aatgacgttg
     3781 ttatgtactt ggcgcacgat attaaaacgc cccttacatc cattatcggt tatttgagcc
     3841 tgcttgacga ggctccagac atgccggtag atcaaaaggc aaagtatgtg catatcacgt
     3901 tggacaaagc gtatcgactc gaacagctaa tcgacgagtt ttttgagatt acacggtata
     3961 acctacaaac gataacgcta acaaaaacgc acatagacct atactatatg ctggtgcaga
     4021 tgaccgatga attttatcct cagctttccg cacatggaaa acaggcggtt attcacgccc
     4081 ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc gagagtcttt aacaacattt
     4141 tgaaaaacgc cgctgcatac agtgaggata acagcatcat tgacattacc gcgggcctct
     4201 ccggggatgt ggtgtcaatc gaattcaaga acactggaag catcccaaaa gataagctag
     4261 ctgccatatt tgaaaagttc tataggctgg acaatgctcg ttcttccgat acgggtggcg
     4321 cgggacttgg attggcgatt gcaaaagaaa ttattgttca gcatggaggg cagatttacg
     4381 cggaaagcaa tgataactat acgacgttta gggtagagct tccagggttc tgttgcaaag
     4441 ttttaaataa agaataaaat ccc
//
LOCUS       DAFKHN010000271         3157 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.164, whole genome shotgun sequence.
ACCESSION   DAFKHN010000271 DAFKHN010000000
VERSION     DAFKHN010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.164"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            297..1265
                     /locus_tag="LY912_003095"
     CDS             297..1265
                     /locus_tag="LY912_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBM6956678.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1258..2289
                     /gene="vanA"
                     /locus_tag="LY912_003096"
     CDS             1258..2289
                     /gene="vanA"
                     /locus_tag="LY912_003096"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBM6956679.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2295..2903
                     /locus_tag="LY912_003097"
     CDS             2295..2903
                     /locus_tag="LY912_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBM6956680.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          935 a          601 c          767 g          854 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccg cttccagcga tgccagactt
       61 ggttgataaa aggaggtcct aagagatgta tataattttt taggaaaatc tcaaggttat
      121 ctttactttt tcttaggaaa ttaacaattt aatattaaga aacggctcgt tcttacacgg
      181 tagacttaat accgtaagaa cgagccgttt tcgttcttca gagaaagatt tgacaagatt
      241 accattggca tccccgtttt atttggtgcc tttcacagaa agggttggtc ttaattatga
      301 ataacatcgg cattactgtt tatggatgtg agcaggatga ggcagatgca ttccatgctc
      361 tttcgcctcg ctttggcgtt atggcaacga taattaacgc caacgtgtcg gaatccaacg
      421 ccaaatccgc gcctttcaat caatgtatca gtgtgggaca taaatcagag atttccgcct
      481 ctattcttct tgcgctgaag agagccggtg tgaaatatat ttctacccga agcatcggct
      541 gcaatcatat agatacaact gctgctaaga gaatgggcat cactgtcgac aatgtggcgt
      601 actcgccgga tagcgttgcc gattatacta tgatgctaat tcttatggca gtacgcaacg
      661 taaaatcgat tgtgcgctct gtggaaaaac atgatttcag gttggacagc gaccgtggca
      721 aggtactcag cgacatgaca gttggtgtgg tgggaacggg ccagataggc aaagcggtta
      781 ttgagcggct gcgaggattt ggatgtaaag tgttggctta tagtcgcagc cgaagtatag
      841 aggtaaacta tgtaccgttt gatgagttgc tgcaaaatag cgatatcgtt acgcttcatg
      901 tgccgctcaa tacggatacg cactatatta tcagccacga acaaatacag agaatgaagc
      961 aaggagcatt tcttatcaat actgggcgcg gtccacttgt agatacctat gagttggtta
     1021 aagcattaga aaacgggaaa ctgggcggtg ccgcattgga tgtattggaa ggagaggaag
     1081 agtttttcta ctctgattgc acccaaaaac caattgataa tcaattttta cttaaacttc
     1141 aaagaatgcc taacgtgata atcacaccgc atacggccta ttataccgag caagcgttgc
     1201 gtgataccgt tgaaaaaacc attaaaaact gtttggattt tgaaaggaga caggagcatg
     1261 aatagaataa aagttgcaat actgtttggg ggttgctcag aggagcatga cgtatcggta
     1321 aaatctgcaa tagagatagc cgctaacatt aataaagaaa aatacgagcc gttatacatt
     1381 ggaattacga aatctggtgt atggaaaatg tgcgaaaaac cttgcgcgga atgggaaaac
     1441 gacaattgct attcagctgt actctcgccg gataaaaaaa tgcacggatt acttgttaaa
     1501 aagaaccatg aatatgaaat caaccatgtt gatgtagcat tttcagcttt gcatggcaag
     1561 tcaggtgaag atggatccat acaaggtctg tttgaattgt ccggtatccc ttttgtaggc
     1621 tgcgatattc aaagctcagc aatttgtatg gacaaatcgt tgacatacat cgttgcgaaa
     1681 aatgctggga tagctactcc cgccttttgg gttattaata aagatgatag gccggtggca
     1741 gctacgttta cctatcctgt ttttgttaag ccggcgcgtt caggctcatc cttcggtgtg
     1801 aaaaaagtca atagcgcgga cgaattggac tacgcaattg aatcggcaag acaatatgac
     1861 agcaaaatct taattgagca ggctgtttcg ggctgtgagg tcggttgtgc ggtattggga
     1921 aacagtgccg cgttagttgt tggcgaggtg gaccaaatca ggctgcagta cggaatcttt
     1981 cgtattcatc aggaagtcga gccggaaaaa ggctctgaaa acgcagttat aaccgttccc
     2041 gcagaccttt cagcagagga gcgaggacgg atacaggaaa cggcaaaaaa aatatataaa
     2101 gcgctcggct gtagaggtct agcccgtgtg gatatgtttt tacaagataa cggccgcatt
     2161 gtactgaacg aagtcaatac tctgcccggt ttcacgtcat acagtcgtta tccccgtatg
     2221 atggccgctg caggtattgc acttcccgaa ctgattgacc gcttgatcgt attagcgtta
     2281 aaggggtgat aagcatggaa ataggattta cttttttaga tgaaatagta cacggtgttc
     2341 gttgggacgc taaatatgcc acttgggata atttcaccgg aaaaccggtt gacggttatg
     2401 aagtaaatcg cattgtaggg acatacgagt tggctgaatc gcttttgaag gcaaaagaac
     2461 tggctgctac ccaagggtac ggattgcttc tatgggacgg ttaccgtcct aagcgtgctg
     2521 taaactgttt tatgcaatgg gctgcacagc cggaaaataa cctgacaaag gaaagttatt
     2581 atcccaatat tgaccgaact gagatgattt caaaaggata cgtggcttca aaatcaagcc
     2641 atagccgcgg cagtgccatt gatcttacgc tttatcgatt agacacgggt gagcttgtac
     2701 caatggggag ccgatttgat tttatggatg aacgctctca tcatgcggca aatggaatat
     2761 catgcaatga agcgcaaaat cgcagacgtt tgcgctccat catggaaaac agtgggtttg
     2821 aagcatatag cctcgaatgg tggcactatg tattaagaga cgaaccatac cccaatagct
     2881 attttgattt ccccgttaaa taaactttta accgttgcac ggacaaacta tataagctaa
     2941 ctctttcggc aggaaacccg acgtatgtaa ctggttctta gggaatttat atatagtaga
     3001 tagtattgaa gatgtaaggc agagcgatat tgcggtcatt atctgcgtgc gctgcggcaa
     3061 gatagcctga taataagact gatcgcatag aggggtggta tttcacaccg cccattgtgg
     3121 ttctgttgca aagttttaaa taaagaataa aatccct
//
LOCUS       DAFKHN010000272         3079 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.166, whole genome shotgun sequence.
ACCESSION   DAFKHN010000272 DAFKHN010000000
VERSION     DAFKHN010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.166"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..731
                     /locus_tag="LY912_003098"
     CDS             <1..731
                     /locus_tag="LY912_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBM6956681.1"
                     /translation="TIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIENLKAY
                     LTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGENTKTV
                     HSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINEFLTT
                     FFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEYIDQQ
                     TKATQVSQFDLVLEKNGSNWKIIE"
     gene            976..1092
                     /locus_tag="LY912_003099"
     CDS             976..1092
                     /locus_tag="LY912_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBM6956682.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            1108..3027
                     /gene="tet(M)"
                     /locus_tag="LY912_003100"
     CDS             1108..3027
                     /gene="tet(M)"
                     /locus_tag="LY912_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBM6956683.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLMQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT         1054 a          495 c          624 g          906 t
ORIGIN      
        1 ccaccatcat agaaaaggaa tatgtcgata ctcatcatgt ggaaaatttt gtagagaact
       61 ttgcgaaagt ctactattca tgggaactaa acgacaagtc cattgataat cgcatagaaa
      121 acctgaaagc atatctgaca gaggaacttc aagctctgaa tgtcgataca gttcgtaaag
      181 atattcctgt atcgtcttct gtaaaaggat ttcagatatg gacggtagaa gcagatggcg
      241 acaatcaatt tgatgtaacc tacagtgtag accaactcat tacagagggg gaaaatacaa
      301 agaccgtcca ctctgcttat atagtgagtg tctatgtaga cagtactgga aatatggtcc
      361 tcattaagaa tccgaccatt actagcatac caaagaaatc agactataaa ccaaaagcta
      421 ttgaaagtga gggtacggtt gattccatta caaccaatga aatcaatgag tttttaacga
      481 cgttcttcaa gctctatcct acagcgacag ccagtgaact ttcctactat gtgaatgacg
      541 ggatattaaa accaatcgga aaagagtaca tctttcaaga actggtaaat cctatttaca
      601 atcgtaagga taatcaagtc acggtatcgc tgacagtgga gtatatcgac cagcagacca
      661 aagcaacgca ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga
      721 ttatagaata acaaatattg gtacattatt acagctattt tgtaatcacg tactctcttt
      781 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtatcta
      841 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
      901 tgggaacaaa taattggatg tcctttttta ggagggctta gttttttgca cccagtttaa
      961 gaataccttt atcatgtgat tctaaagtat ccggagaata tctgtatgct ttgtatgcct
     1021 atggttatgc ataaaaatcc cagtgataag agtatttatc actgggattt ttatgccctt
     1081 ttgggctttt gaatggagga aaatcacatg aaaattatta atattggagt tttagctcat
     1141 gttgatgcgg gaaaaactac cttaacagaa agcttattat ataacagtgg agcgattaca
     1201 gaattaggaa gcgtggacaa aggtacaacg aggacggata atacgctttt agaacgtcag
     1261 agaggaatta caattcagac aggaataacc tcttttcagt gggaaaatac gaaggtgaac
     1321 atcatagaca cgccaggaca tatggatttc ttagcagaag tatatcgttc attatcagtt
     1381 ttagatgggg caattctact gatttctgca aaagatggcg tacaagcaca aactcgtata
     1441 ttatttcatg cacttaggaa aatggggatt cccacaatct tttttatcaa taagattgac
     1501 caaaatggaa ttgatttatc aacggtttat caggatatta aagagaaact ttctgccgaa
     1561 attgtaatca aacagaaggt agaactgtat cctaatatgt gtgtgacgaa ctttaccgaa
     1621 tctgaacaat gggatacggt aatagaggga aacgatgacc ttttagagaa atatatgtcc
     1681 ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa gcataagatt tcagaattgc
     1741 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
     1801 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
     1861 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
     1921 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
     1981 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
     2041 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
     2101 ctattgccac agagagagag aattgaaaat ccgctccctc tgatgcaaac aactgttgaa
     2161 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
     2221 gacccgcttc tacaatatta tgtggattct acgacacatg aaattatact ttctttctta
     2281 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
     2341 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
     2401 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
     2461 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
     2521 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
     2581 tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
     2641 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
     2701 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
     2761 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
     2821 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
     2881 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
     2941 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
     3001 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
     3061 tgttaaataa gatgaaata
//
LOCUS       DAFKHN010000273         3079 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.167, whole genome shotgun sequence.
ACCESSION   DAFKHN010000273 DAFKHN010000000
VERSION     DAFKHN010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.167"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..731
                     /locus_tag="LY912_003101"
     CDS             <1..731
                     /locus_tag="LY912_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBM6956684.1"
                     /translation="TIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIENLKAY
                     LTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGENTKTV
                     HSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINEFLTT
                     FFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEYIDQQ
                     TKATQVSQFDLVLEKNGSNWKIIE"
     gene            976..1092
                     /locus_tag="LY912_003102"
     CDS             976..1092
                     /locus_tag="LY912_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBM6956685.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            1108..3027
                     /gene="tet(M)"
                     /locus_tag="LY912_003103"
     CDS             1108..3027
                     /gene="tet(M)"
                     /locus_tag="LY912_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBM6956686.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT         1053 a          496 c          624 g          906 t
ORIGIN      
        1 ccaccatcat agaaaaggaa tatgtcgata ctcatcatgt ggaaaatttt gtagagaact
       61 ttgcgaaagt ctactattca tgggaactaa acgacaagtc cattgataat cgcatagaaa
      121 acctgaaagc atatctgaca gaggaacttc aagctctgaa tgtcgataca gttcgtaaag
      181 atattcctgt atcgtcttct gtaaaaggat ttcagatatg gacggtagaa gcagatggcg
      241 acaatcaatt tgatgtaacc tacagtgtag accaactcat tacagagggg gaaaatacaa
      301 agaccgtcca ctctgcttat atagtgagtg tctatgtaga cagtactgga aatatggtcc
      361 tcattaagaa tccgaccatt actagcatac caaagaaatc agactataaa ccaaaagcta
      421 ttgaaagtga gggtacggtt gattccatta caaccaatga aatcaatgag tttttaacga
      481 cgttcttcaa gctctatcct acagcgacag ccagtgaact ttcctactat gtgaatgacg
      541 ggatattaaa accaatcgga aaagagtaca tctttcaaga actggtaaat cctatttaca
      601 atcgtaagga taatcaagtc acggtatcgc tgacagtgga gtatatcgac cagcagacca
      661 aagcaacgca ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga
      721 ttatagaata acaaatattg gtacattatt acagctattt tgtaatcacg tactctcttt
      781 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtatcta
      841 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
      901 tgggaacaaa taattggatg tcctttttta ggagggctta gttttttgca cccagtttaa
      961 gaataccttt atcatgtgat tctaaagtat ccggagaata tctgtatgct ttgtatgcct
     1021 atggttatgc ataaaaatcc cagtgataag agtatttatc actgggattt ttatgccctt
     1081 ttgggctttt gaatggagga aaatcacatg aaaattatta atattggagt tttagctcat
     1141 gttgatgcgg gaaaaactac cttaacagaa agcttattat ataacagtgg agcgattaca
     1201 gaattaggaa gcgtggacaa aggtacaacg aggacggata atacgctttt agaacgtcag
     1261 agaggaatta caattcagac aggaataacc tcttttcagt gggaaaatac gaaggtgaac
     1321 atcatagaca cgccaggaca tatggatttc ttagcagaag tatatcgttc attatcagtt
     1381 ttagatgggg caattctact gatttctgca aaagatggcg tacaagcaca aactcgtata
     1441 ttatttcatg cacttaggaa aatggggatt cccacaatct tttttatcaa taagattgac
     1501 caaaatggaa ttgatttatc aacggtttat caggatatta aagagaaact ttctgccgaa
     1561 attgtaatca aacagaaggt agaactgtat cctaatatgt gtgtgacgaa ctttaccgaa
     1621 tctgaacaat gggatacggt aatagaggga aacgatgacc ttttagagaa atatatgtcc
     1681 ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa gcataagatt tcagaattgc
     1741 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
     1801 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
     1861 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
     1921 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
     1981 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
     2041 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
     2101 ctattgccac agagagagag aattgaaaat ccgctccctc tgctgcaaac aactgttgaa
     2161 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
     2221 gacccgcttc tacaatatta tgtggattct acgacacatg aaattatact ttctttctta
     2281 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
     2341 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
     2401 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
     2461 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
     2521 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
     2581 tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag ccctgttagt
     2641 accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt aaaaaaagct
     2701 ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca ggaatatctt
     2761 tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa
     2821 aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga atatcgtagt
     2881 gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa agggtaccat
     2941 gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat agataaagta
     3001 cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa tatggtttct
     3061 tgttaaataa gatgaaata
//
LOCUS       DAFKHN010000274         2038 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.188, whole genome shotgun sequence.
ACCESSION   DAFKHN010000274 DAFKHN010000000
VERSION     DAFKHN010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.188"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..75
                     /locus_tag="LY912_003104"
     CDS             <1..75
                     /locus_tag="LY912_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBM6956687.1"
                     /translation="SIGKAVEEGYESVRLAPEKITMFE"
     gene            429..1907
                     /gene="msr(C)"
                     /locus_tag="LY912_003105"
     CDS             429..1907
                     /gene="msr(C)"
                     /locus_tag="LY912_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBM6956688.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1954..>2038
                     /locus_tag="LY912_003106"
     CDS             1954..>2038
                     /locus_tag="LY912_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBM6956689.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNL"
BASE COUNT          716 a          325 c          432 g          565 t
ORIGIN      
        1 tcaataggaa aagcggtaga agaaggttac gagtctgttc gtttagcacc agaaaagatc
       61 actatgttcg aataaaaggt tttcagttac tattcagtag ctattgcttt ttttgaatcg
      121 tgtgtggtaa cctaataaaa aaggaggtcg gaaaaatgac tgcatcgatg aaattacgtt
      181 tcgaactttt gaataacaac taaataaatt caaaagacat gtataaacaa caatttcatg
      241 gatggagtat gtccattttt tcgaacgaca gtagaatagg tgaaagctat gacagatttg
      301 gtgatttagt catagttatt tcgttcagag taggaaaaga tgtgatgcag tttttttgca
      361 aacagatttt tctgctcttt tttagtatcg ataattgttg ttttacatga aataggagtg
      421 taaaacatat ggaaaattta gcagtaaata taacaaatct acaagtcagc tttggcaacc
      481 agctagaact atctattgat tctcttcgtg tctatcagca agatcgtata gggatcatag
      541 gagaaaatgg tgtcggtaaa tcgactttgc tcaaactaat agccggtgaa ctttttcccg
      601 atcatgggaa aatccaaaca gagatcacct tcaactacct gcctcaatta acctatctcg
      661 ctgaagcaaa ggacctaaat ttggaattag ccagtcattt ccagttaaga ctggaagaaa
      721 cttcagagcg gaaatggagc ggaggggaag aacgaaagat cgagttgata cgtcttcttt
      781 cttcttatga acaagggatg cttctagacg agccaacaac ccatctagat agaaaaagta
      841 ttgatcgact gattgaagag cttcgttatt attatggtac gctggttttt gttagtcatg
      901 atcgctattt tctagatgag ctagcatcga aaatctggga agtaaaagac ggagaaatcc
      961 gagagttttc ggggaattat agtgcctatc tcactcaaaa ggaattggag aaaaagactc
     1021 agctacgaga agcagagtcg atcatgaaag agaaaaaacg attggaaaaa tcgatccaag
     1081 aaaagaaaaa acaagcggaa aagttggaaa aagtgtccag taaaaagaaa aagcaacaaa
     1141 tcagactgga tcggttgtct tcctctaaac aaaaagacag tgtacaaaaa gccatccaaa
     1201 agaatgcgaa aacattagag agaagactcc aaaaaatagg agaaacaacc aagccgcagc
     1261 agatgaaaca aatccgtttt ccagtaccaa aatctcttga actccacagc cgctatccca
     1321 tcatgggaca aaatgtccaa ttggaaagaa gtgggagaac attactggta aatggtgatt
     1381 ttcagttttc tttaggtaaa aaaatcgcga ttgtcggtga aaatggttca ggtaagacaa
     1441 ccttattaga acatatccgc aaacaaggag aaggaatcct tctctctccg aaagtaagct
     1501 ttcaagtata tcagcaaaag ggttatcaaa tgacatctga agaatccatc attcgttttg
     1561 tcatgagaca aacagagttt tcagaatcgc ttgtccgtag tttgctgaat cacttagggt
     1621 ttgctcagga aactttgacg aaaccgttat gtacattaag tgggggagaa gcgacccgtc
     1681 tgacgattgc tttgcttttt actaagccaa gtaatgtgtt gctgttagat gaaccgacta
     1741 attttattga tatggcaacg atcgaagctt tagagaagct aatgcaaata tatccgggaa
     1801 cgattttgtt tacttctcat gattcttact ttgtcgagcg tacggctgat gaagtttatg
     1861 aaataaaagg gcagaaaata aaaaaagtac ttacgagaaa tttttaaatg tgctacgatg
     1921 attttcgtga caaatttaaa ggagtggtac agattgccta caaataaaaa agaaggaata
     1981 atttttacaa caatgatgtg ttttttgatg gtcttgggga tgagcgcgta taatttat
//
LOCUS       DAFKHN010000275         1660 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.200, whole genome shotgun sequence.
ACCESSION   DAFKHN010000275 DAFKHN010000000
VERSION     DAFKHN010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.200"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            85..1458
                     /gene="tet(L)"
                     /locus_tag="LY912_003107"
     CDS             85..1458
                     /gene="tet(L)"
                     /locus_tag="LY912_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HBM6956690.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT          480 a          239 c          328 g          613 t
ORIGIN      
        1 gttatataaa tatggtttct tgttaaataa gatgaaatat tttttaataa agatttgaat
       61 taaagtgtaa aggaggaatt aattatgaag tgtaatgaat gtaacagggt taaatacaac
      121 caaattttaa tttggctttg cgttttatct ttttttagcg tattaaatga aatggttttg
      181 aacgtctcat tacctgatat tgcaaatgat tttaataaac cacctgcgag tacaaactgg
      241 gtgaacacag cctttatgtt aaccttttcc attggaacag ctgtatatgg aaagctatct
      301 gatcaattag gcatcaaaag gttactccta tttggaatta taataaattg tttcgggtcg
      361 gtaattgggt ttgttggcca ttctttcttt tccttactta ttatggctcg ttttattcaa
      421 ggggctggtg cagctgcatt tccagcactc gtaatggttg tagttgcgcg ctatattcca
      481 aaggaaaata ggggtaaagc atttggtctt attggatcga tagtagccat gggagaagga
      541 gtcggtccag cgattggtgg aatgatagcc cattatattc attggtccta tcttctactc
      601 attcctatga taacaattat cactgttccg tttcttatga aattattaaa gaaagaagta
      661 aggataaaag gtcattttga tatcaaagga attatactaa tgtctgtagg cattgtattt
      721 tttatgttgt ttacaacatc atatagcatt tcttttctta tcgttagcgt gctgtcattc
      781 ctgatatttg taaaacatat caggaaagta acagatcctt ttgttgatcc cggattaggg
      841 aaaaatatac cttttatgat tggagttctt tgtgggggaa ttatatttgg aacagtagca
      901 gggtttgtct ctatggttcc ttatatgatg aaagatgttc accagctaag tactgccgaa
      961 atcggaagtg taattatttt ccctggaaca atgagtgtca ttattttcgg ctacattggt
     1021 gggatacttg ttgatagaag aggtccttta tacgtgttaa acatcggagt tacatttctt
     1081 tctgttagct ttttaactgc ttcctttctt ttagaaacaa catcatggtt catgacaatt
     1141 ataatcgtat ttgttttagg tgggctttcg ttcaccaaaa cagttatatc aacaattgtt
     1201 tcaagtagct tgaaacagca ggaagctggt gctggaatga gtttgcttaa ctttaccagc
     1261 tttttatcag agggaacagg tattgcaatt gtaggtggtt tattatccat acccttactt
     1321 gatcaaaggt tgttacctat ggaagttgat cagtcaactt atctgtatag taatttgtta
     1381 ttactttttt caggaatcat tgtcattagt tggctggtta ccttgaatgt atataaacat
     1441 tctcaaaggg atttctaaat cgttaaggga tcaactttgg gagagagttc aaaattgatc
     1501 ctttttttat aacaggaatt caaatctttt tgttccatta aagggcgcga ttgctgaata
     1561 aaagatacga gagacctctc ttgtatcttt tttattttga gtggttttgt ccgttacact
     1621 agaaaaccga aagacaataa aaattttatt cttgctgagt
//
LOCUS       DAFKHN010000276         1557 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.205, whole genome shotgun sequence.
ACCESSION   DAFKHN010000276 DAFKHN010000000
VERSION     DAFKHN010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.205"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            113..598
                     /gene="vanZ"
                     /locus_tag="LY912_003108"
     CDS             113..598
                     /gene="vanZ"
                     /locus_tag="LY912_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBM6956691.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(885..1214)
                     /locus_tag="LY912_003109"
     CDS             complement(885..1214)
                     /locus_tag="LY912_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBM6956692.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
BASE COUNT          534 a          234 c          238 g          551 t
ORIGIN      
        1 aagaaccgtc aggtttagct aagtggtgag tagttcactt taaaacccac gttaactagg
       61 acattgctat actaatgata caacttaaac aaaagaatta gaggaaatta tattgggaaa
      121 aatattatct agaggattgc tagctttata tttagtgaca ctaatctggt tagtgttatt
      181 caaattacaa tacaatattt tatcagtatt taattatcat caaagaagtc ttaacttgac
      241 tccatttact gctactggga atttcagaga gatgatagat aatgttataa tctttattcc
      301 atttggcttg cttttgaatg tcaattttaa agaaatcgga tttttaccta agtttgcttt
      361 tgtactggtt ttaagtctta cttttgaaat aattcaattt atcttcgcta ttggagcgac
      421 agacataaca gatgtaatta caaatactgt tggaggcttt cttggactga aattatatgg
      481 tttaagcaat aagcatatga atcaaaaaaa attagacaga gttattattt ttgtaggtat
      541 acttttgctc gtattattgc tcgtttaccg tacccattta agaataaatt acgtgtaaga
      601 tgtctaaatc aagcaatctg atctttcata cacataaaga tattgaatga attggattag
      661 atggaaaacg ggatgtgggg aaactcgccc gtaggtgtga agtgagggga aaaccggtga
      721 taaagtaaaa agcttaccta acactatagt aacaaagaaa gcccaattat caattttagt
      781 gctgaggaat tggtctcttt aataaatttc cttaacgttg taaatccgca ttttcctgac
      841 ggtaccccca aactaagatt tcatagatag attttctgat aactttaaaa aacacgaata
      901 gcggaaagga tgtcttcatt cgctaaagag taataaacta cttttccatc ttgacgtgat
      961 tttgccattc catgtttttt taaaaaacgt aaatggtgtg acgttgtagc gacactagca
     1021 gtaagtattt ctgctaaatc acagacgcac atttccttat aggtttctaa agcatagaaa
     1081 attttaattc tagaaaaatc gctgaaacat ttccctaaca caagtaagtt tgaaaaatct
     1141 ttttgatcca atttattttt tattccattt actttttctt tatgtacgac agtcacttgg
     1201 caaacttttt tcattcatct cacctcacat tcaaacgatt atttgaatga agtataccta
     1261 tttgatcact cttttgtcaa tctaccttaa ttccaataca ctattataag caatttcatg
     1321 tattgaagta aacttacttg caagtgcgtt tttgattcca agttaaaaac atattattat
     1381 tctacataat ttcctaatca aataaaactc ctttgaaaat tgttctaaag gagttttatt
     1441 attttgtatt tctactaaaa atagcgtaca atgtaattac taagtaatta cgaaatgtaa
     1501 aataatggag gaaataatat ggttctgttg caaagtttta aatctactat caaataa
//
LOCUS       DAFKHN010000277         1281 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.222, whole genome shotgun sequence.
ACCESSION   DAFKHN010000277 DAFKHN010000000
VERSION     DAFKHN010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.222"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            261..1172
                     /locus_tag="LY912_003110"
     CDS             261..1172
                     /locus_tag="LY912_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HBM6956693.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          456 a          190 c          261 g          374 t
ORIGIN      
        1 accttatttg atagtagatt taaaactttg caacagaacc cccattgtca acaggcagtt
       61 cagcctcgtt aaattcagca tgggtatcac ttatgaaaat tcatctacat tggtgataat
      121 agtaaatcca gtagggcgaa ataattgact gtaatttacg gggcaaaacg gcacaatctc
      181 aaacgagatt gtgccgttta aggggaagat tctagaaata tttcatactt ccaactatat
      241 agttaaggag gagactgaaa atgaagaagt tgtttttttt attgttattg ttattcttaa
      301 tatacttagg ttatgactac gttaatgaag cactgttttc tcaggaaaaa gtcgaatttc
      361 aaaattatga tcaaaatccc aaagaacatt tagaaaatag tgggacttct gaaaataccc
      421 aagagaaaac aattacagaa gaacaggttt atcaaggaaa tctgctatta atcaatagta
      481 aatatcctgt tcgccaagaa agtgtgaagt cagatatcgt gaatttatct aaacatgacg
      541 aattaataaa tggatacggg ttgcttgata gtaatattta tatgtcaaaa gaaatagcac
      601 aaaaattttc agagatggtc aatgatgctg taaagggtgg cgttagtcat tttattatta
      661 atagtggcta tcgagacttt gatgagcaaa gtgtgcttta ccaagaaatg ggggctgagt
      721 atgccttacc agcaggttat agtgagcata attcaggttt atcactagat gtaggatcaa
      781 gcttgacgaa aatggaacga gcccctgaag gaaagtggat agaagaaaat gcttggaaat
      841 acgggttcat tttacgttat ccagaggaca aaacagagtt aacaggaatt caatatgaac
      901 catggcatat tcgctatgtt ggtttaccac atagtgcgat tatgaaagaa aagaatttcg
      961 ttctcgagga atatatggat tacctaaaag aagaaaaaac catttctgtt agtgtaaatg
     1021 gggaaaaata tgagatcttt tattatcctg ttactaaaaa taccaccatt catgtgccga
     1081 ctaatcttcg ttatgagata tcaggaaaca atatagacgg tgtaattgtg acagtgtttc
     1141 ccggatcaac acatactaat tcaaggaggt aaggatggcg gaatgaaacc aacgaaatta
     1201 atgaacagca ttattgtact agcacttttg gggtaacgtt agctttttaa cagaattagg
     1261 cagaagtcgc ccatcctcta t
//
LOCUS       DAFKHN010000278          945 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.236, whole genome shotgun sequence.
ACCESSION   DAFKHN010000278 DAFKHN010000000
VERSION     DAFKHN010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.236"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            107..841
                     /locus_tag="LY912_003111"
     CDS             107..841
                     /locus_tag="LY912_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HBM6956694.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          380 a          124 c          133 g          308 t
ORIGIN      
        1 tgatgaggtt gaacttttac acaagattgt ggacttgact aaaataagtg gttataatgg
       61 attgttaata taaacattca ttataacctc ataggagtgg gttataatga acaaaaaaaa
      121 tataaaagat agtcaaaact ttattacttc aaagcatcat ataaatgaaa ttttgagaaa
      181 tgtacattta aatacaaatg ataatattat tgagattggt tcagggaaag gtcatttcac
      241 gtttgaatta gctaaaaggt gtaattatgt aaccgccatt gaaatagatc ctaaattatg
      301 taggataact aaaaacaaac ttattgaata tgagaacttc caggttatca ataaagatat
      361 tttacaattt aagtttccta aaaataagtc atataagata tatggaaata taccctacaa
      421 tataagtaca gatataattc gaaaaattgt ttttgaaagc acagctacag aaagttattt
      481 aatagtggaa tatggatttg ctaaaaggtt gctaaataca aatcgttcac tagcactatt
      541 tttaatgaca gaagttgata tatccatatt aagtaaaatc cctagagaat actttcatcc
      601 aaaacctaga gttaatagct cgttaattgt attaaaaaga cacccttcaa aaatatcact
      661 caaagataga aaacaatatg aaaattttgt tatgaaatgg gttaacaaag aatacataaa
      721 actattttcc aaaaaccaat tttatcaagc cttaaaatat gcaagaattg acgatttaaa
      781 caatattagc tttgaacaat tcttgtctct tttcaatagc tataaattat ttaatagata
      841 agttaagggg tgcataaact gcatccctta acttatctta ttttgcttaa acaatcttgg
      901 cccgtaaact gcataactca tatgtaaatc gctccttttt aggtg
//
LOCUS       DAFKHN010000279          814 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.245, whole genome shotgun sequence.
ACCESSION   DAFKHN010000279 DAFKHN010000000
VERSION     DAFKHN010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.245"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            201..749
                     /gene="aac(6')"
                     /locus_tag="LY912_003112"
     CDS             201..749
                     /gene="aac(6')"
                     /locus_tag="LY912_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBM6956695.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          287 a          122 c          176 g          229 t
ORIGIN      
        1 cagagttttt tcctccaatt gatggctttc ctgatctttc ctattttgaa taaagtgttt
       61 ctgtataatt tttttatttt ataagtaaga taaataatga aagaatagag atactgattg
      121 gtagctaaag atttttgagc gagaacattt cgttttttca aaaggactgt tagaataagc
      181 aagaacaagg gggaagacgt atgataatca gtgaatttga ccgtaataat ccagtattga
      241 aagatcagct ttctgattta ctgagactga cttggccgga agaatatgga gacagctcgg
      301 cagaagaagt agaagaaatg atgaatccag aacgaatcgc ggtagcagcg gtagaccaag
      361 atgagttagt aggatttatt ggtgcaatcc ctcaatacgg tatcacaggt tgggaattgc
      421 atccattagt tgtagaaagc tcccgacgaa agaaccaaat aggtactcga ttagtcaatt
      481 acttagaaaa agaagtagct tccagaggag gaatcacgat ttatttaggt acggatgatt
      541 tagaccatgg aacaacgtta agtcaaacgg acctgtatga gcatacattt gataaagtgg
      601 cttccatcca gaaccttcgt gaacatccgt atgaattcta tgaaaaatta ggttataaaa
      661 tcgtaggtgt cttaccaaat gcaaatggct gggacaaacc ggatatttgg atggcaaaaa
      721 cgattattcc tcgaccaaat tctcaataat aaaaagaggt tgtgacagaa gtaatcagct
      781 tcaagaaata agaaggaatt tacgaaaatt actt
//
LOCUS       DAFKHN010000280          622 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.260, whole genome shotgun sequence.
ACCESSION   DAFKHN010000280 DAFKHN010000000
VERSION     DAFKHN010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.260"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..515
                     /locus_tag="LY912_003113"
     CDS             <1..515
                     /locus_tag="LY912_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family
                     protein"
                     /protein_id="HBM6956696.1"
                     /translation="HGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIES
                     FMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLE
                     DSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGR
                     KEIYKRTYKD"
BASE COUNT          269 a           38 c          111 g          204 t
ORIGIN      
        1 tgcacggttt agattataca gatattagtg aatgtactat tgataataaa caaaatgtat
       61 tagaagagta tatattgttg cgtgaaacta tttataatga tttaactgat atagaaaaag
      121 attatataga aagttttatg gaaagactaa atgcaacaac agtttttgag ggtaaaaagt
      181 gtttatgcca taatgatttt agttgtaatc atctattgtt agatggcaat aatagattaa
      241 ctggaataat tgattttgga gattctggaa ttatagatga atattgtgat tttatatact
      301 tacttgaaga tagtgaagaa gaaataggaa caaattttgg agaagatata ttaagaatgt
      361 atggaaatat agatattgag aaagcaaaag aatatcaaga tatagttgaa gaatattatc
      421 ctattgaaac tattgtttat ggaattaaaa atattaaaca ggaatttatc gaaaatggta
      481 gaaaagaaat ttataaaagg acttataaag attgattata taatatatga aaagctatta
      541 taaaagacat tagtattaaa tagtttaaaa aaatgaaaaa taataaagga agtgagtcaa
      601 gtccagactc ctgtgtaaaa tg
//
LOCUS       DAFKHN010000281          420 bp    DNA     linear   BCT 30-DEC-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate Hospitalised patient
            SAMN20285599-rid13665153.guided.287, whole genome shotgun sequence.
ACCESSION   DAFKHN010000281 DAFKHN010000000
VERSION     DAFKHN010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20285599
            Sequence Read Archive: SRR15186359
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 29-DEC-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001213510.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001213510.1
            Genome Coverage       :: 51x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/30/2021 01:39:21
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,114
            CDSs (total)                      :: 3,047
            Genes (coding)                    :: 2,970
            CDSs (with protein)               :: 2,970
            Genes (RNA)                       :: 67
            rRNAs                             :: 2, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 3, 3 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 35 of 77
            Pseudo Genes (internal stop)      :: 19 of 77
            Pseudo Genes (multiple problems)  :: 10 of 77
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20285599-rid13665153.guided.287"
                     /isolate="Hospitalised patient"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Ireland: Dublin"
                     /lat_lon="53.34 N 6.26 W"
                     /collection_date="2018-06-11"
                     /collected_by="National MRSA Reference Laboratory,
                     Ireland"
     gene            <1..>420
                     /locus_tag="LY912_003114"
     CDS             <1..>420
                     /locus_tag="LY912_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBM6956697.1"
                     /translation="YIKIKGRWHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFE
                     FLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYD
                     DNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAY"
BASE COUNT          167 a           40 c           82 g          131 t
ORIGIN      
        1 ctatatcaaa attaagggac gttggcatta tccaaaaact gatgagatag tctatggtat
       61 ggatcaattt ataggagagc caaattattg gagtaaagga attggtacaa gatatattaa
      121 attgattttt gaatttttga aaaaagaaag aaatgctaat gcagttattt tagaccctca
      181 taaaaataat ccaagagcaa taagggcata ccaaaaatct ggttttagaa ttattgaaga
      241 tttgccagaa catgaattac acgagggcaa aaaagaagat tgttatttaa tggaatatag
      301 atatgatgat aatgccacaa atgttaaggc aatgaaatat ttaattgagc attactttga
      361 taatttcaaa gtagatagta ttgaaataat cggtagtggt tatgatagtg tggcatattt
//
